locus-tag	class	description
IC780_RS00010	COG0592	DNA-directed DNA polymerase activity
IC780_RS00020	COG0187	DNA topoisomerase II activity
IC780_RS00030	COG0586	Pfam SNARE associated Golgi protein
IC780_RS00035	COG0488	(ABC) transporter
IC780_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC780_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC780_RS00110	COG1047	Peptidyl-prolyl cis-trans
IC780_RS00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC780_RS00125	COG0196	riboflavin kinase activity
IC780_RS00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC780_RS00140	COG1309	transcriptional regulator
IC780_RS00145	COG1116	anion transmembrane transporter activity
IC780_RS00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_RS00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_RS00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_RS00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_RS00170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC780_RS00170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC780_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS00190	COG0546	phosphoglycolate phosphatase activity
IC780_RS00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC780_RS00250	COG0728	peptidoglycan biosynthetic process
IC780_RS00275	COG1596	polysaccharide export
IC780_RS00280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC780_RS00290	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC780_RS00295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC780_RS00305	COG1086	Polysaccharide biosynthesis protein
IC780_RS00340	COG1216	Glycosyl transferase, family 2
IC780_RS00340	COG0463	Glycosyl transferase, family 2
IC780_RS00345	COG0110	maltose O-acetyltransferase activity
IC780_RS00360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC780_RS00365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC780_RS00390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC780_RS00400	COG2186	Transcriptional regulator
IC780_RS00410	COG0277	FAD linked oxidase domain protein
IC780_RS00415	COG1448	Aminotransferase
IC780_RS00425	COG1802	Transcriptional regulator
IC780_RS00440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC780_RS00510	COG0564	pseudouridine synthase activity
IC780_RS00550	COG0251	oxidation-reduction process
IC780_RS00555	COG1113	amino acid transport
IC780_RS00560	COG1113	amino acid transport
IC780_RS00580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC780_RS00585	COG1960	acyl-CoA dehydrogenase activity
IC780_RS00590	COG1024	Enoyl-CoA hydratase
IC780_RS00595	COG1024	Enoyl-CoA hydratase
IC780_RS00600	COG0477	Major facilitator Superfamily
IC780_RS00605	COG3916	Acyl-homoserine-lactone synthase
IC780_RS00615	COG2197	response regulator
IC780_RS00625	COG1960	acyl-CoA dehydrogenase activity
IC780_RS00630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC780_RS00630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC780_RS00630	COG3321	synthase
IC780_RS00630	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC780_RS00670	COG0271	Belongs to the BolA IbaG family
IC780_RS00680	COG1192	Involved in chromosome partitioning
IC780_RS00695	COG0586	Pfam SNARE associated Golgi protein
IC780_RS00700	COG2259	Doxx family
IC780_RS00705	COG4399	Belongs to the UPF0754 family
IC780_RS00710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC780_RS00710	COG0519	Catalyzes the synthesis of GMP from XMP
IC780_RS00715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC780_RS00725	COG0735	belongs to the Fur family
IC780_RS00760	COG0281	malic enzyme
IC780_RS00770	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS00780	COG1280	lysine exporter protein (LysE YggA)
IC780_RS00790	COG1121	(ABC) transporter
IC780_RS00840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC780_RS00845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC780_RS00855	COG0386	Belongs to the glutathione peroxidase family
IC780_RS00870	COG1309	transcriptional regulator
IC780_RS00875	COG0697	spore germination
IC780_RS00885	COG0758	DNA mediated transformation
IC780_RS00920	COG1309	transcriptional regulator
IC780_RS00955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC780_RS00970	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC780_RS01015	COG2814	Major facilitator Superfamily
IC780_RS01025	COG1253	flavin adenine dinucleotide binding
IC780_RS01035	COG2860	membrane
IC780_RS01040	COG0477	Major facilitator Superfamily
IC780_RS01050	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_RS01065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC780_RS01080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC780_RS01085	COG0235	Class ii aldolase
IC780_RS01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_RS01095	COG0431	NADPH-dependent FMN reductase
IC780_RS01100	COG0606	chelatase, subunit chli
IC780_RS01110	COG0347	Belongs to the P(II) protein family
IC780_RS01115	COG0004	ammonium transporteR
IC780_RS01125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC780_RS01125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC780_RS01160	COG0795	lipopolysaccharide-transporting ATPase activity
IC780_RS01165	COG0795	lipopolysaccharide-transporting ATPase activity
IC780_RS01170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC780_RS01175	COG0793	Belongs to the peptidase S41A family
IC780_RS01190	COG2197	response regulator
IC780_RS01200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC780_RS01210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC780_RS01215	COG4974	Belongs to the 'phage' integrase family
IC780_RS01245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC780_RS01250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC780_RS01260	COG0494	nUDIX hydrolase
IC780_RS01280	COG0697	spore germination
IC780_RS01290	COG1538	Outer membrane efflux protein
IC780_RS01310	COG3275	phosphorelay sensor kinase activity
IC780_RS01320	COG0181	hydroxymethylbilane synthase activity
IC780_RS01365	COG1716	ATPase activity
IC780_RS01370	COG0546	phosphoglycolate phosphatase activity
IC780_RS01465	COG0596	Alpha beta hydrolase
IC780_RS01470	COG2056	Na+-H+ antiporter family
IC780_RS01485	COG0326	Molecular chaperone. Has ATPase activity
IC780_RS01500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC780_RS01565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC780_RS01580	COG1289	transmembrane transporter activity
IC780_RS01595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC780_RS01605	COG0497	DNA recombination
IC780_RS01615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC780_RS01625	COG0237	dephospho-CoA kinase activity
IC780_RS01675	COG0195	Participates in both transcription termination and antitermination
IC780_RS01685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC780_RS01690	COG1320	monovalent cation:proton antiporter activity
IC780_RS01695	COG2212	antiporter activity
IC780_RS01700	COG1863	multisubunit Na H antiporter MnhE subunit
IC780_RS01705	COG0651	ATP synthesis coupled electron transport
IC780_RS01710	COG1006	Multisubunit Na H antiporter MnhC subunit
IC780_RS01715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC780_RS01715	COG2111	Na H antiporter
IC780_RS01730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC780_RS01745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_RS01760	COG2226	methyltransferase
IC780_RS01785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC780_RS01790	COG1074	ATP-dependent DNA helicase activity
IC780_RS01795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC780_RS01800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC780_RS01810	COG1185	polyribonucleotide nucleotidyltransferase activity
IC780_RS01815	COG0598	Magnesium transport protein CorA
IC780_RS01820	COG0789	Transcriptional regulator
IC780_RS01825	COG0484	heat shock protein binding
IC780_RS01835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC780_RS01840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC780_RS01840	COG0475	glutathione-regulated potassium exporter activity
IC780_RS01845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC780_RS01870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC780_RS01880	COG4535	Mg2 and Co2 transporter CorC
IC780_RS01895	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC780_RS01895	COG0644	oxidoreductase
IC780_RS01905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC780_RS01920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_RS01925	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC780_RS01935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC780_RS01935	COG0493	'glutamate synthase
IC780_RS01965	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC780_RS01980	COG0534	Mate efflux family protein
IC780_RS01990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC780_RS01995	COG4221	oxidoreductase activity
IC780_RS02000	COG0583	DNA-binding transcription factor activity
IC780_RS02015	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_RS02020	COG1530	ribonuclease E activity
IC780_RS02035	COG2378	regulation of single-species biofilm formation
IC780_RS02040	COG0625	glutathione transferase activity
IC780_RS02050	COG0583	DNA-binding transcription factor activity
IC780_RS02095	COG0583	DNA-binding transcription factor activity
IC780_RS02120	COG0473	3-isopropylmalate dehydrogenase activity
IC780_RS02175	COG1301	dicarboxylic acid transport
IC780_RS02185	COG1560	Kdo2-lipid A biosynthetic process
IC780_RS02190	COG1280	lysine exporter protein (LysE YggA)
IC780_RS02200	COG0488	(ABC) transporter
IC780_RS02205	COG2900	Belongs to the SlyX family
IC780_RS02215	COG1733	regulation of RNA biosynthetic process
IC780_RS02240	COG0210	DNA helicase
IC780_RS02245	COG0724	RNA recognition motif
IC780_RS02265	COG4651	solute:proton antiporter activity
IC780_RS02265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC780_RS02290	COG0788	formyltetrahydrofolate deformylase activity
IC780_RS02395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC780_RS02395	COG2813	Specifically methylates the guanine in position
IC780_RS02405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC780_RS02415	COG4774	siderophore transport
IC780_RS02425	COG0740	serine-type endopeptidase activity
IC780_RS02445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC780_RS02445	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC780_RS02450	COG0857	belongs to the CobB CobQ family
IC780_RS02450	COG0280	phosphate acetyltransferase
IC780_RS02455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC780_RS02465	COG0800	Aldolase
IC780_RS02475	COG3265	gluconokinase activity
IC780_RS02480	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS02490	COG2267	carboxylic ester hydrolase activity
IC780_RS02505	COG0793	Belongs to the peptidase S41A family
IC780_RS02540	COG1426	Protein conserved in bacteria
IC780_RS02580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC780_RS02590	COG1162	GTPase activity
IC780_RS02595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC780_RS02610	COG1538	Outer membrane efflux protein
IC780_RS02615	COG0577	efflux transmembrane transporter activity
IC780_RS02615	COG1136	(ABC) transporter
IC780_RS02645	COG0028	Belongs to the TPP enzyme family
IC780_RS02650	COG0440	acetolactate synthase activity
IC780_RS02655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC780_RS02690	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC780_RS02705	COG0084	hydrolase, TatD family'
IC780_RS02715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC780_RS02725	COG0583	DNA-binding transcription factor activity
IC780_RS02735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC780_RS02840	COG2814	Major facilitator Superfamily
IC780_RS02855	COG1230	cation diffusion facilitator family transporter
IC780_RS02880	COG2814	Major facilitator Superfamily
IC780_RS02890	COG0697	spore germination
IC780_RS02925	COG3622	Belongs to the hyi family
IC780_RS02930	COG2084	Dehydrogenase
IC780_RS02935	COG1024	Enoyl-CoA hydratase
IC780_RS02940	COG0784	Response regulator, receiver
IC780_RS02940	COG2205	protein histidine kinase activity
IC780_RS02940	COG5002	protein histidine kinase activity
IC780_RS02960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC780_RS02970	COG3956	TIGRFAM MazG family protein
IC780_RS02975	COG1555	photosystem II stabilization
IC780_RS02980	COG0617	tRNA 3'-terminal CCA addition
IC780_RS02985	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC780_RS03010	COG3028	Belongs to the UPF0307 family
IC780_RS03015	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_RS03030	COG0625	glutathione transferase activity
IC780_RS03035	COG1238	metal cluster binding
IC780_RS03045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC780_RS03075	COG0072	phenylalanine-tRNA ligase activity
IC780_RS03105	COG0248	Ppx GppA phosphatase
IC780_RS03155	COG1764	response to oxidative stress
IC780_RS03160	COG1846	Transcriptional regulator
IC780_RS03170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC780_RS03230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC780_RS03235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC780_RS03240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC780_RS03250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC780_RS03300	COG1214	PFAM Peptidase M22, glycoprotease
IC780_RS03315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC780_RS03325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC780_RS03330	COG0561	phosphatase activity
IC780_RS03340	COG2132	Multicopper oxidase
IC780_RS03365	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS03375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC780_RS03380	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC780_RS03410	COG1063	alcohol dehydrogenase
IC780_RS03415	COG0583	DNA-binding transcription factor activity
IC780_RS03420	COG1960	acyl-CoA dehydrogenase activity
IC780_RS03425	COG2814	Major facilitator Superfamily
IC780_RS03430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC780_RS03440	COG1309	transcriptional regulator
IC780_RS03455	COG1053	succinate dehydrogenase
IC780_RS03460	COG0583	DNA-binding transcription factor activity
IC780_RS03475	COG0583	DNA-binding transcription factor activity
IC780_RS03485	COG0583	DNA-binding transcription factor activity
IC780_RS03500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_RS03545	COG0583	DNA-binding transcription factor activity
IC780_RS03550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC780_RS03580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC780_RS03600	COG0745	RESPONSE REGULATOR receiver
IC780_RS03615	COG3706	GGDEF domain
IC780_RS03640	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC780_RS03655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC780_RS03670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC780_RS03675	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC780_RS03700	COG0583	DNA-binding transcription factor activity
IC780_RS03720	COG0668	transmembrane transport
IC780_RS03730	COG2081	HI0933 family
IC780_RS03735	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC780_RS03770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC780_RS03770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC780_RS03780	COG0489	protein tyrosine kinase activity
IC780_RS03785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC780_RS03830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC780_RS03840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC780_RS03855	COG0730	response to heat
IC780_RS03865	COG1196	nuclear chromosome segregation
IC780_RS03885	COG2223	nitrite transmembrane transporter activity
IC780_RS03890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC780_RS03895	COG1877	trehalose-phosphatase activity
IC780_RS03900	COG0596	Alpha beta hydrolase
IC780_RS03900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC780_RS03900	COG2226	methyltransferase
IC780_RS03915	COG4106	trans-aconitate 2-methyltransferase activity
IC780_RS03930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC780_RS03935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC780_RS03940	COG0009	L-threonylcarbamoyladenylate synthase
IC780_RS03945	COG3101	peptidyl-lysine hydroxylation
IC780_RS03950	COG1399	metal-binding, possibly nucleic acid-binding protein
IC780_RS03975	COG1652	LysM domain
IC780_RS03980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC780_RS03980	COG0352	thiamine-phosphate diphosphorylase activity
IC780_RS03980	COG0351	phosphomethylpyrimidine kinase
IC780_RS03990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC780_RS04020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC780_RS04050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC780_RS04065	COG0358	DNA primase activity
IC780_RS04075	COG0564	pseudouridine synthase activity
IC780_RS04100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC780_RS04120	COG0583	DNA-binding transcription factor activity
IC780_RS04125	COG0473	3-isopropylmalate dehydrogenase activity
IC780_RS04135	COG0657	acetylesterase activity
IC780_RS04140	COG4638	Rieske (2fe-2S)
IC780_RS04145	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS04165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC780_RS04165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC780_RS04175	COG1981	membrane
IC780_RS04190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC780_RS04200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC780_RS04220	COG0456	acetyltransferase
IC780_RS04230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC780_RS04235	COG0492	ferredoxin-NADP+ reductase activity
IC780_RS04240	COG1674	ftsk spoiiie
IC780_RS04245	COG1280	lysine exporter protein (LysE YggA)
IC780_RS04260	COG2894	cell division
IC780_RS04275	COG0204	Acyl-transferase
IC780_RS04280	COG2885	chlorophyll binding
IC780_RS04285	COG0210	DNA helicase
IC780_RS04295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC780_RS04310	COG0121	glutamine amidotransferase
IC780_RS04325	COG2914	Belongs to the UPF0125 (RnfH) family
IC780_RS04330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC780_RS04335	COG0735	belongs to the Fur family
IC780_RS04355	COG1968	undecaprenyl-diphosphatase activity
IC780_RS04365	COG0420	3'-5' exonuclease activity
IC780_RS04385	COG1090	epimerase
IC780_RS04400	COG2050	protein possibly involved in aromatic compounds catabolism
IC780_RS04410	COG2814	Major facilitator Superfamily
IC780_RS04415	COG0405	Gamma-glutamyltransferase
IC780_RS04450	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS04480	COG3586	endonuclease activity
IC780_RS04485	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC780_RS04510	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS04530	COG0477	Major facilitator Superfamily
IC780_RS04535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC780_RS04555	COG0531	amino acid
IC780_RS04560	COG2040	homocysteine
IC780_RS04585	COG1309	transcriptional regulator
IC780_RS04590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC780_RS04595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC780_RS04605	COG1607	acyl-coa hydrolase
IC780_RS04615	COG0523	cobalamin synthesis protein
IC780_RS04625	COG4681	YaeQ
IC780_RS04635	COG1649	PFAM Uncharacterised BCR, COG1649
IC780_RS04635	COG0726	polysaccharide deacetylase
IC780_RS04640	COG1215	transferase activity, transferring glycosyl groups
IC780_RS04650	COG1024	Enoyl-CoA hydratase
IC780_RS04680	COG1414	Transcriptional regulator
IC780_RS04715	COG2271	Major facilitator Superfamily
IC780_RS04725	COG2267	carboxylic ester hydrolase activity
IC780_RS04730	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS04745	COG0028	Belongs to the TPP enzyme family
IC780_RS04760	COG0242	peptide deformylase activity
IC780_RS04765	COG2066	Belongs to the glutaminase family
IC780_RS04770	COG2207	Transcriptional regulator
IC780_RS04775	COG2223	nitrite transmembrane transporter activity
IC780_RS04810	COG0306	phosphate transporter
IC780_RS04830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC780_RS04875	COG4181	ATPase activity
IC780_RS04880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC780_RS04905	COG0583	DNA-binding transcription factor activity
IC780_RS04915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_RS04920	COG1773	rubredoxin
IC780_RS04970	COG2851	Citrate transporter
IC780_RS04975	COG1253	flavin adenine dinucleotide binding
IC780_RS05015	COG0804	urea catabolic process
IC780_RS05025	COG0830	nickel cation binding
IC780_RS05045	COG0742	ribosomal rna small subunit methyltransferase
IC780_RS05050	COG0768	penicillin binding
IC780_RS05075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC780_RS05080	COG2878	Part of a membrane complex involved in electron transport
IC780_RS05085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC780_RS05095	COG3384	dioxygenase
IC780_RS05135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC780_RS05165	COG1674	ftsk spoiiie
IC780_RS05495	COG0006	proline dipeptidase activity
IC780_RS05500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_RS05505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_RS05530	COG0583	DNA-binding transcription factor activity
IC780_RS05575	COG0741	lytic transglycosylase activity
IC780_RS05575	COG1388	LysM domain
IC780_RS05585	COG4174	ABC transporter (Permease)
IC780_RS05590	COG4239	(ABC) transporter, permease
IC780_RS05595	COG4172	Belongs to the ABC transporter superfamily
IC780_RS05620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC780_RS05630	COG4251	negative regulation of phosphorylation
IC780_RS05630	COG3706	GGDEF domain
IC780_RS05630	COG2203	Gaf domain
IC780_RS05630	COG5001	Diguanylate cyclase
IC780_RS05640	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC780_RS05640	COG1902	pentaerythritol trinitrate reductase activity
IC780_RS05655	COG0251	oxidation-reduction process
IC780_RS05665	COG0583	DNA-binding transcription factor activity
IC780_RS05685	COG4269	membrane
IC780_RS05735	COG1846	Transcriptional regulator
IC780_RS05785	COG1113	amino acid transport
IC780_RS05795	COG0531	amino acid
IC780_RS05815	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS05835	COG1113	amino acid transport
IC780_RS05855	COG0697	spore germination
IC780_RS05875	COG1960	acyl-CoA dehydrogenase activity
IC780_RS05885	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS05890	COG1024	Enoyl-CoA hydratase
IC780_RS05895	COG2814	Major facilitator Superfamily
IC780_RS05910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_RS05930	COG1944	ATP diphosphatase activity
IC780_RS05960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC780_RS05975	COG0583	DNA-binding transcription factor activity
IC780_RS05980	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC780_RS05985	COG2072	flavoprotein involved in K transport
IC780_RS06000	COG1309	transcriptional regulator
IC780_RS06005	COG1741	Belongs to the pirin family
IC780_RS06020	COG2072	flavoprotein involved in K transport
IC780_RS06030	COG2252	PERMEase
IC780_RS06035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC780_RS06040	COG3038	cytochrome b561
IC780_RS06050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC780_RS06060	COG0527	aspartate kinase activity
IC780_RS06070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC780_RS06085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC780_RS06100	COG0667	Aldo Keto reductase
IC780_RS06110	COG1765	OsmC-like protein
IC780_RS06170	COG0625	glutathione transferase activity
IC780_RS06175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC780_RS06195	COG3634	alkyl hydroperoxide reductase activity
IC780_RS06215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_RS06230	COG1643	Atp-dependent helicase
IC780_RS06250	COG2814	Major facilitator Superfamily
IC780_RS06255	COG3135	benzoate transporter
IC780_RS06260	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS06265	COG0543	2 iron, 2 sulfur cluster binding
IC780_RS06265	COG0633	Ferredoxin
IC780_RS06270	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC780_RS06275	COG4638	Rieske (2fe-2S)
IC780_RS06285	COG0583	DNA-binding transcription factor activity
IC780_RS06295	COG2871	sodium ion transport
IC780_RS06380	COG1570	exodeoxyribonuclease VII activity
IC780_RS06415	COG1280	lysine exporter protein (LysE YggA)
IC780_RS06420	COG1278	Cold shock
IC780_RS06450	COG2814	Major facilitator Superfamily
IC780_RS06460	COG0667	Aldo Keto reductase
IC780_RS06480	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC780_RS06480	COG0517	IMP dehydrogenase activity
IC780_RS06485	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC780_RS06495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC780_RS06500	COG1137	ATPase activity
IC780_RS06505	COG1538	Outer membrane efflux protein
IC780_RS06535	COG4122	O-methyltransferase activity
IC780_RS06545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC780_RS06590	COG1560	Kdo2-lipid A biosynthetic process
IC780_RS06610	COG1469	GTP cyclohydrolase I activity
IC780_RS06620	COG1294	oxidase, subunit
IC780_RS06625	COG1271	oxidase subunit
IC780_RS06635	COG0583	DNA-binding transcription factor activity
IC780_RS06640	COG0402	S-adenosylhomocysteine deaminase activity
IC780_RS06655	COG2814	Major facilitator Superfamily
IC780_RS06675	COG4774	siderophore transport
IC780_RS06680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC780_RS06690	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS06700	COG1522	sequence-specific DNA binding
IC780_RS06705	COG0626	cystathionine gamma-synthase activity
IC780_RS06715	COG1278	Cold shock
IC780_RS06720	COG1309	transcriptional regulator
IC780_RS06800	COG3209	COG3209 Rhs family protein
IC780_RS06845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC780_RS06850	COG3713	MltA-interacting MipA family protein
IC780_RS06865	COG2076	Multidrug Resistance protein
IC780_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS06895	COG3220	belongs to the UPF0276 family
IC780_RS06905	COG1595	DNA-templated transcription, initiation
IC780_RS06915	COG0583	DNA-binding transcription factor activity
IC780_RS06920	COG1914	H( )-stimulated, divalent metal cation uptake system
IC780_RS06940	COG4770	biotin carboxylase activity
IC780_RS06945	COG0038	chloride channel
IC780_RS06990	COG1063	alcohol dehydrogenase
IC780_RS07005	COG0439	Biotin carboxylase
IC780_RS07010	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_RS07015	COG1733	regulation of RNA biosynthetic process
IC780_RS07030	COG0864	Transcriptional regulator
IC780_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC780_RS07045	COG1116	anion transmembrane transporter activity
IC780_RS07070	COG0477	Major facilitator Superfamily
IC780_RS07175	COG0590	tRNA wobble adenosine to inosine editing
IC780_RS07180	COG2807	transmembrane transport
IC780_RS07195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_RS07200	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC780_RS07210	COG0789	Transcriptional regulator
IC780_RS07220	COG1760	l-serine dehydratase
IC780_RS07225	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS07225	COG2030	dehydratase
IC780_RS07230	COG3396	Phenylacetate-CoA oxygenase
IC780_RS07235	COG3460	Phenylacetate-CoA oxygenase
IC780_RS07240	COG3396	Phenylacetate-CoA oxygenase
IC780_RS07245	COG2151	metal-sulfur cluster biosynthetic enzyme
IC780_RS07250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_RS07255	COG1024	Enoyl-CoA hydratase
IC780_RS07260	COG1024	Enoyl-CoA hydratase
IC780_RS07265	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_RS07275	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC780_RS07280	COG3327	negative regulation of DNA-templated transcription, initiation
IC780_RS07290	COG2050	protein possibly involved in aromatic compounds catabolism
IC780_RS07300	COG0406	alpha-ribazole phosphatase activity
IC780_RS07320	COG3179	chitinase
IC780_RS07370	COG1309	transcriptional regulator
IC780_RS07375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC780_RS07390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC780_RS07395	COG0531	amino acid
IC780_RS07400	COG0753	catalase activity
IC780_RS07405	COG3038	cytochrome b561
IC780_RS07420	COG0583	DNA-binding transcription factor activity
IC780_RS07430	COG1414	Transcriptional regulator
IC780_RS07435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_RS07450	COG1840	ABC-type Fe3 transport system, periplasmic component
IC780_RS07455	COG3842	ATPase activity
IC780_RS07470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC780_RS07475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC780_RS07480	COG2814	Major facilitator Superfamily
IC780_RS07485	COG1960	acyl-CoA dehydrogenase activity
IC780_RS07490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC780_RS07500	COG1024	Enoyl-CoA hydratase
IC780_RS07515	COG2814	Major facilitator Superfamily
IC780_RS07525	COG0183	Belongs to the thiolase family
IC780_RS07530	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS07540	COG1024	Enoyl-CoA hydratase
IC780_RS07545	COG1960	acyl-CoA dehydrogenase activity
IC780_RS07565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC780_RS07570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC780_RS07580	COG2814	Major facilitator Superfamily
IC780_RS07590	COG1960	acyl-CoA dehydrogenase activity
IC780_RS07605	COG0583	DNA-binding transcription factor activity
IC780_RS07615	COG4770	biotin carboxylase activity
IC780_RS07620	COG1024	Enoyl-CoA hydratase
IC780_RS07625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC780_RS07630	COG1960	acyl-CoA dehydrogenase activity
IC780_RS07635	COG1309	transcriptional regulator
IC780_RS07640	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_RS07660	COG0583	DNA-binding transcription factor activity
IC780_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS07725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC780_RS07745	COG0784	Response regulator, receiver
IC780_RS07745	COG2205	protein histidine kinase activity
IC780_RS07785	COG0765	amino acid transport
IC780_RS07790	COG0765	amino acid transport
IC780_RS07800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC780_RS07805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC780_RS07815	COG1280	lysine exporter protein (LysE YggA)
IC780_RS07820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC780_RS07830	COG1045	serine acetyltransferase
IC780_RS07845	COG0583	DNA-binding transcription factor activity
IC780_RS07850	COG0625	glutathione transferase activity
IC780_RS07855	COG0625	glutathione transferase activity
IC780_RS07860	COG0583	DNA-binding transcription factor activity
IC780_RS07870	COG1346	cytolysis
IC780_RS07895	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC780_RS07900	COG3052	prosthetic group binding
IC780_RS07920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC780_RS07940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_RS07950	COG1294	oxidase, subunit
IC780_RS07955	COG1271	oxidase subunit
IC780_RS07975	COG0477	Major facilitator Superfamily
IC780_RS07985	COG4521	taurine ABC transporter
IC780_RS07990	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC780_RS07995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_RS08000	COG2175	clavaminate synthase activity
IC780_RS08010	COG1953	Uracil, thiamine, allantoin
IC780_RS08020	COG0583	DNA-binding transcription factor activity
IC780_RS08030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC780_RS08045	COG0640	Transcriptional regulator
IC780_RS08050	COG0798	PFAM Bile acid sodium symporter
IC780_RS08055	COG0431	NADPH-dependent FMN reductase
IC780_RS08060	COG0583	DNA-binding transcription factor activity
IC780_RS08075	COG3634	alkyl hydroperoxide reductase activity
IC780_RS08110	COG1301	dicarboxylic acid transport
IC780_RS08115	COG0436	Aminotransferase
IC780_RS08125	COG0386	Belongs to the glutathione peroxidase family
IC780_RS08130	COG1917	Cupin 2, conserved barrel domain protein
IC780_RS08130	COG2207	Transcriptional regulator
IC780_RS08165	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC780_RS08190	COG0012	GTP binding
IC780_RS08195	COG2011	ABC-type metal ion transport system permease component
IC780_RS08200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC780_RS08210	COG1464	Belongs to the NlpA lipoprotein family
IC780_RS08240	COG0765	amino acid transport
IC780_RS08245	COG0765	amino acid transport
IC780_RS08250	COG1126	abc transporter atp-binding protein
IC780_RS08260	COG1522	sequence-specific DNA binding
IC780_RS08285	COG2197	response regulator
IC780_RS08305	COG0583	DNA-binding transcription factor activity
IC780_RS08315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC780_RS08325	COG0697	spore germination
IC780_RS08345	COG3121	Chaperone
IC780_RS08350	COG3539	Fimbrial protein
IC780_RS08375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC780_RS08375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC780_RS08415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC780_RS08430	COG2353	YceI-like domain
IC780_RS08440	COG3698	Phosphodiester glycosidase
IC780_RS08455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC780_RS08460	COG0506	proline dehydrogenase activity
IC780_RS08460	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC780_RS08460	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC780_RS08470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC780_RS08475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC780_RS08495	COG1132	(ABC) transporter
IC780_RS08500	COG3122	Protein conserved in bacteria
IC780_RS08505	COG3619	membrane
IC780_RS08525	COG2850	peptidyl-arginine hydroxylation
IC780_RS08530	COG0424	maF-like protein
IC780_RS08570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC780_RS08580	COG1192	Involved in chromosome partitioning
IC780_RS08585	COG1475	DNA binding
IC780_RS08590	COG0811	peptide transport
IC780_RS08600	COG1132	(ABC) transporter
IC780_RS08625	COG0084	hydrolase, TatD family'
IC780_RS08690	COG0776	regulation of translation
IC780_RS08705	COG2431	L-lysine efflux transmembrane transporter activity
IC780_RS08720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC780_RS08770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC780_RS08785	COG0305	Participates in initiation and elongation during chromosome replication
IC780_RS08865	COG4695	Portal protein
IC780_RS08985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC780_RS09010	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC780_RS09035	COG0601	transmembrane transport
IC780_RS09040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC780_RS09045	COG4172	Belongs to the ABC transporter superfamily
IC780_RS09075	COG0702	epimerase
IC780_RS09080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC780_RS09100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC780_RS09130	COG0316	Belongs to the HesB IscA family
IC780_RS09135	COG0822	iron-sulfur transferase activity
IC780_RS09160	COG0776	regulation of translation
IC780_RS09165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC780_RS09170	COG2207	Transcriptional regulator
IC780_RS09175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_RS09180	COG1960	acyl-CoA dehydrogenase activity
IC780_RS09185	COG1960	acyl-CoA dehydrogenase activity
IC780_RS09200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC780_RS09205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC780_RS09220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC780_RS09225	COG0406	alpha-ribazole phosphatase activity
IC780_RS09240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC780_RS09245	COG0730	response to heat
IC780_RS09270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC780_RS09285	COG1131	(ABC) transporter
IC780_RS09290	COG0842	Transport permease protein
IC780_RS09295	COG0842	Transport permease protein
IC780_RS09345	COG2226	methyltransferase
IC780_RS09370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC780_RS09405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC780_RS09415	COG0133	tryptophan synthase activity
IC780_RS09430	COG3706	GGDEF domain
IC780_RS09445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC780_RS09450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC780_RS09455	COG0022	dehydrogenase e1 component
IC780_RS09460	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_RS09465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_RS09475	COG1063	alcohol dehydrogenase
IC780_RS09480	COG3781	membrane
IC780_RS09490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_RS09490	COG3453	Protein conserved in bacteria
IC780_RS09500	COG0730	response to heat
IC780_RS09515	COG3708	Transcriptional regulator
IC780_RS09515	COG2207	Transcriptional regulator
IC780_RS09525	COG0477	Major facilitator Superfamily
IC780_RS09535	COG1027	Aspartate ammonia-lyase
IC780_RS09550	COG0583	DNA-binding transcription factor activity
IC780_RS09555	COG0583	DNA-binding transcription factor activity
IC780_RS09560	COG0183	Belongs to the thiolase family
IC780_RS09565	COG2031	fatty acid transporter
IC780_RS09580	COG0583	DNA-binding transcription factor activity
IC780_RS09605	COG2814	Major facilitator Superfamily
IC780_RS09635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_RS09640	COG2610	gluconate transmembrane transporter activity
IC780_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS09650	COG2207	Transcriptional regulator
IC780_RS09670	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS09680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_RS09695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_RS09695	COG0543	2 iron, 2 sulfur cluster binding
IC780_RS09700	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC780_RS09705	COG4638	Rieske (2fe-2S)
IC780_RS09715	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC780_RS09720	COG4149	molybdate abc transporter
IC780_RS09725	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC780_RS09750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC780_RS09755	COG3251	PFAM MbtH domain protein
IC780_RS09765	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS09770	COG1169	isochorismate synthase
IC780_RS09775	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC780_RS09780	COG1535	isochorismatase
IC780_RS09780	COG3433	isochorismatase activity
IC780_RS09785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_RS09790	COG4771	TonB-dependent receptor
IC780_RS09850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_RS09855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_RS09860	COG0745	RESPONSE REGULATOR receiver
IC780_RS09865	COG2205	protein histidine kinase activity
IC780_RS09875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC780_RS09880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC780_RS09890	COG0753	catalase activity
IC780_RS09900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC780_RS09925	COG3539	Fimbrial protein
IC780_RS09955	COG0601	transmembrane transport
IC780_RS09960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC780_RS09980	COG1132	(ABC) transporter
IC780_RS09985	COG1132	(ABC) transporter
IC780_RS10005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_RS10015	COG0805	protein transport
IC780_RS10020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC780_RS10035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_RS10040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_RS10045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_RS10050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_RS10080	COG4771	TonB-dependent receptor
IC780_RS10085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_RS10090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_RS10120	COG2175	clavaminate synthase activity
IC780_RS10135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_RS10140	COG0667	Aldo Keto reductase
IC780_RS10155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC780_RS10160	COG2175	clavaminate synthase activity
IC780_RS10280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC780_RS10300	COG1120	ATPase activity
IC780_RS10305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC780_RS10335	COG1566	PFAM secretion protein HlyD family protein
IC780_RS10345	COG2271	Major facilitator Superfamily
IC780_RS10360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_RS10375	COG2188	Transcriptional regulator
IC780_RS10455	COG1309	transcriptional regulator
IC780_RS10480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC780_RS10510	COG0583	DNA-binding transcription factor activity
IC780_RS10515	COG4948	Mandelate Racemase Muconate Lactonizing
IC780_RS10520	COG4829	muconolactone delta-isomerase
IC780_RS10530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC780_RS10535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC780_RS10540	COG0183	Belongs to the thiolase family
IC780_RS10545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC780_RS10550	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS10565	COG3733	amine oxidase
IC780_RS10575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_RS10585	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS10595	COG4638	Rieske (2fe-2S)
IC780_RS10615	COG0154	amidase activity
IC780_RS10625	COG2814	Major facilitator Superfamily
IC780_RS10650	COG1960	acyl-CoA dehydrogenase activity
IC780_RS10655	COG0583	DNA-binding transcription factor activity
IC780_RS10660	COG1414	Transcriptional regulator
IC780_RS10675	COG2391	methyltransferase activity
IC780_RS10685	COG4993	Dehydrogenase
IC780_RS10690	COG3659	wide pore channel activity
IC780_RS10695	COG3420	alginic acid biosynthetic process
IC780_RS10705	COG3485	protocatechuate 3,4-dioxygenase
IC780_RS10710	COG3485	protocatechuate 3,4-dioxygenase
IC780_RS10715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC780_RS10720	COG2271	Major facilitator Superfamily
IC780_RS10725	COG0596	Alpha beta hydrolase
IC780_RS10730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC780_RS10735	COG0183	Belongs to the thiolase family
IC780_RS10740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC780_RS10745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC780_RS10755	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC780_RS10765	COG2323	membrane
IC780_RS10770	COG0148	phosphopyruvate hydratase activity
IC780_RS10810	COG1902	pentaerythritol trinitrate reductase activity
IC780_RS10810	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC780_RS10835	COG0542	response to heat
IC780_RS10840	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC780_RS10870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC780_RS10875	COG0569	domain protein
IC780_RS10880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC780_RS10895	COG4774	siderophore transport
IC780_RS10900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC780_RS10910	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC780_RS10925	COG1294	oxidase, subunit
IC780_RS10930	COG4890	Cyd operon protein YbgT
IC780_RS10955	COG0552	protein localization to endoplasmic reticulum
IC780_RS10980	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC780_RS10985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC780_RS10990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC780_RS11000	COG0583	DNA-binding transcription factor activity
IC780_RS11005	COG0024	Methionine aminopeptidase
IC780_RS11035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC780_RS11035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC780_RS11040	COG1105	Belongs to the carbohydrate kinase PfkB family
IC780_RS11045	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC780_RS11045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC780_RS11045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC780_RS11080	COG0659	secondary active sulfate transmembrane transporter activity
IC780_RS11095	COG1113	amino acid transport
IC780_RS11105	COG1522	sequence-specific DNA binding
IC780_RS11120	COG1011	Hydrolase
IC780_RS11125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC780_RS11135	COG2137	regulation of response to DNA damage stimulus
IC780_RS11150	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC780_RS11170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC780_RS11185	COG0575	Belongs to the CDS family
IC780_RS11190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC780_RS11215	COG3852	Histidine kinase
IC780_RS11220	COG2204	response regulator
IC780_RS11275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC780_RS11280	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC780_RS11300	COG0697	spore germination
IC780_RS11315	COG0303	'Molybdopterin
IC780_RS11320	COG0315	cyclic pyranopterin monophosphate synthase activity
IC780_RS11320	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC780_RS11335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC780_RS11340	COG0243	molybdopterin cofactor binding
IC780_RS11350	COG0243	molybdopterin cofactor binding
IC780_RS11355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_RS11360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_RS11360	COG2146	nitrite reductase [NAD(P)H] activity
IC780_RS11370	COG0745	RESPONSE REGULATOR receiver
IC780_RS11375	COG1116	anion transmembrane transporter activity
IC780_RS11375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_RS11395	COG0511	ligase activity, forming carbon-carbon bonds
IC780_RS11455	COG0069	glutamate synthase activity
IC780_RS11485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC780_RS11500	COG1335	isochorismatase
IC780_RS11510	COG1454	alcohol dehydrogenase
IC780_RS11515	COG0824	Thioesterase
IC780_RS11530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC780_RS11555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC780_RS11560	COG2030	dehydratase
IC780_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS11570	COG0183	Belongs to the thiolase family
IC780_RS11580	COG0583	DNA-binding transcription factor activity
IC780_RS11585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC780_RS11595	COG1522	sequence-specific DNA binding
IC780_RS11600	COG3135	benzoate transporter
IC780_RS11625	COG0589	response to stress
IC780_RS11630	COG0488	(ABC) transporter
IC780_RS11675	COG0668	transmembrane transport
IC780_RS11685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC780_RS11690	COG2423	ornithine cyclodeaminase activity
IC780_RS11695	COG4264	IucA IucC family
IC780_RS11705	COG4264	IucA IucC family
IC780_RS11750	COG1605	Chorismate mutase
IC780_RS11765	COG0625	glutathione transferase activity
IC780_RS11795	COG0308	aminopeptidase N
IC780_RS11815	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC780_RS11825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC780_RS11830	COG1454	alcohol dehydrogenase
IC780_RS11850	COG0531	amino acid
IC780_RS11855	COG4303	Ethanolamine ammonia lyase large subunit
IC780_RS11860	COG4302	ethanolamine ammonia-lyase activity
IC780_RS11865	COG0519	Catalyzes the synthesis of GMP from XMP
IC780_RS11865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC780_RS11870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC780_RS11895	COG0697	spore germination
IC780_RS11900	COG1923	regulation of RNA biosynthetic process
IC780_RS11910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC780_RS11915	COG0802	atpase or kinase
IC780_RS11935	COG1187	pseudouridine synthase activity
IC780_RS11950	COG0583	DNA-binding transcription factor activity
IC780_RS11960	COG2814	Major facilitator Superfamily
IC780_RS11965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC780_RS11995	COG0729	surface antigen
IC780_RS12015	COG0174	glutamine synthetase
IC780_RS12020	COG0745	RESPONSE REGULATOR receiver
IC780_RS12025	COG2205	protein histidine kinase activity
IC780_RS12030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC780_RS12035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC780_RS12040	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC780_RS12065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_RS12070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC780_RS12075	COG1960	acyl-CoA dehydrogenase activity
IC780_RS12090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_RS12095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_RS12100	COG2890	protein-(glutamine-N5) methyltransferase activity
IC780_RS12120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_RS12130	COG3658	cytochrome
IC780_RS12135	COG1215	transferase activity, transferring glycosyl groups
IC780_RS12140	COG0726	polysaccharide deacetylase
IC780_RS12140	COG1649	PFAM Uncharacterised BCR, COG1649
IC780_RS12170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC780_RS12180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC780_RS12205	COG0305	Participates in initiation and elongation during chromosome replication
IC780_RS12210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC780_RS12220	COG1305	Transglutaminase-like
IC780_RS12230	COG2308	Evidence 4 Homologs of previously reported genes of
IC780_RS12260	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC780_RS12265	COG0138	bifunctional purine biosynthesis protein purh
IC780_RS12270	COG0151	Belongs to the GarS family
IC780_RS12275	COG1464	Belongs to the NlpA lipoprotein family
IC780_RS12280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC780_RS12285	COG2011	ABC-type metal ion transport system permease component
IC780_RS12300	COG1301	dicarboxylic acid transport
IC780_RS12345	COG2855	membrane
IC780_RS12360	COG2814	Major facilitator Superfamily
IC780_RS12365	COG3246	L-lysine catabolic process to acetate
IC780_RS12370	COG2175	clavaminate synthase activity
IC780_RS12395	COG0745	RESPONSE REGULATOR receiver
IC780_RS12400	COG0642	Histidine kinase
IC780_RS12405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC780_RS12415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC780_RS12440	COG5002	protein histidine kinase activity
IC780_RS12455	COG2351	hydroxyisourate hydrolase activity
IC780_RS12465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC780_RS12465	COG3008	intermembrane lipid transfer
IC780_RS12470	COG2995	paraquat-inducible protein a
IC780_RS12500	COG2985	domain, Protein
IC780_RS12515	COG2169	Transcriptional regulator
IC780_RS12515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC780_RS12525	COG1309	transcriptional regulator
IC780_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS12615	COG0475	glutathione-regulated potassium exporter activity
IC780_RS12615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC780_RS12620	COG0786	glutamate:sodium symporter activity
IC780_RS12630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC780_RS12640	COG0596	Alpha beta hydrolase
IC780_RS12660	COG0583	DNA-binding transcription factor activity
IC780_RS12665	COG1335	isochorismatase
IC780_RS12770	COG2815	serine threonine protein kinase
IC780_RS12770	COG0515	serine threonine protein kinase
IC780_RS12800	COG1610	YqeY-like protein
IC780_RS12860	COG0778	Nitroreductase
IC780_RS12870	COG0513	Belongs to the DEAD box helicase family
IC780_RS12890	COG2363	Small membrane protein
IC780_RS12915	COG4650	regulator
IC780_RS12920	COG1234	tRNA 3'-trailer cleavage
IC780_RS12925	COG1690	Belongs to the RtcB family
IC780_RS12945	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC780_RS12950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC780_RS12960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC780_RS12980	COG1960	acyl-CoA dehydrogenase activity
IC780_RS12985	COG1301	dicarboxylic acid transport
IC780_RS12995	COG3139	Protein of unknown function (DUF1315)
IC780_RS13000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC780_RS13005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC780_RS13025	COG0642	Histidine kinase
IC780_RS13040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC780_RS13050	COG1720	tRNA m6t6A37 methyltransferase activity
IC780_RS13060	COG0384	phenazine biosynthesis protein PhzF
IC780_RS13065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_RS13070	COG0826	peptidase U32
IC780_RS13075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC780_RS13085	COG4598	ABC transporter
IC780_RS13090	COG4160	amino acid transport
IC780_RS13095	COG4215	(ABC) transporter
IC780_RS13110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_RS13150	COG1131	(ABC) transporter
IC780_RS13155	COG0842	Transport permease protein
IC780_RS13170	COG0772	Belongs to the SEDS family
IC780_RS13175	COG2951	lytic endotransglycosylase activity
IC780_RS13200	COG2207	Transcriptional regulator
IC780_RS13215	COG0052	Belongs to the universal ribosomal protein uS2 family
IC780_RS13220	COG0024	Methionine aminopeptidase
IC780_RS13230	COG2223	nitrite transmembrane transporter activity
IC780_RS13240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_RS13245	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC780_RS13250	COG1960	acyl-CoA dehydrogenase activity
IC780_RS13265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC780_RS13270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC780_RS13275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC780_RS13295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC780_RS13300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC780_RS13305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC780_RS13340	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC780_RS13350	COG0174	glutamine synthetase
IC780_RS13365	COG0512	Glutamine amidotransferase of anthranilate synthase
IC780_RS13380	COG2840	Smr protein MutS2
IC780_RS13390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC780_RS13400	COG0302	gtp cyclohydrolase
IC780_RS13420	COG3739	integral membrane protein
IC780_RS13435	COG1741	Belongs to the pirin family
IC780_RS13445	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC780_RS13450	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS13460	COG2964	Protein conserved in bacteria
IC780_RS13470	COG2423	ornithine cyclodeaminase activity
IC780_RS13475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC780_RS13515	COG2814	Major facilitator Superfamily
IC780_RS13545	COG2879	small protein
IC780_RS13550	COG1966	Carbon starvation protein
IC780_RS13555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC780_RS13570	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC780_RS13595	COG1067	ATP-dependent peptidase activity
IC780_RS13600	COG0583	DNA-binding transcription factor activity
IC780_RS13625	COG1686	Belongs to the peptidase S11 family
IC780_RS13630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC780_RS13655	COG3647	Membrane
IC780_RS13670	COG0616	signal peptide processing
IC780_RS13675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC780_RS13685	COG0573	inorganic phosphate transmembrane transporter activity
IC780_RS13690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC780_RS13695	COG1113	amino acid transport
IC780_RS13700	COG3961	Belongs to the TPP enzyme family
IC780_RS13705	COG1522	sequence-specific DNA binding
IC780_RS13715	COG0076	glutamate decarboxylase activity
IC780_RS13720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC780_RS13745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_RS13780	COG0352	thiamine-phosphate diphosphorylase activity
IC780_RS13815	COG0612	Peptidase, M16
IC780_RS13825	COG1823	symporter activity
IC780_RS13830	COG0583	DNA-binding transcription factor activity
IC780_RS13835	COG0477	Major facilitator Superfamily
IC780_RS13910	COG1196	nuclear chromosome segregation
IC780_RS13910	COG0739	heme binding
IC780_RS13910	COG0741	lytic transglycosylase activity
IC780_RS14020	COG5484	DNA packaging
IC780_RS14020	COG3728	DNA packaging
IC780_RS14210	COG1187	pseudouridine synthase activity
IC780_RS14225	COG1686	Belongs to the peptidase S11 family
IC780_RS14230	COG1252	NADH dehydrogenase
IC780_RS14240	COG0415	Belongs to the DNA photolyase family
IC780_RS14255	COG1215	transferase activity, transferring glycosyl groups
IC780_RS14270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC780_RS14285	COG2070	2-Nitropropane dioxygenase
IC780_RS14340	COG0556	nucleotide-excision repair
IC780_RS14345	COG3706	GGDEF domain
IC780_RS14365	COG0436	Aminotransferase
IC780_RS14390	COG4221	oxidoreductase activity
IC780_RS14400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC780_RS14405	COG1381	Involved in DNA repair and RecF pathway recombination
IC780_RS14415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC780_RS14430	COG0681	Belongs to the peptidase S26 family
IC780_RS14435	COG0481	GTPase activity
IC780_RS14445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC780_RS14465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC780_RS14470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC780_RS14475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC780_RS14485	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC780_RS14490	COG4208	sulfate ABC transporter
IC780_RS14495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC780_RS14500	COG0583	DNA-binding transcription factor activity
IC780_RS14505	COG4625	pathogenesis
IC780_RS14515	COG0602	queuosine metabolic process
IC780_RS14520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC780_RS14535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC780_RS14550	COG1051	belongs to the nudix hydrolase family
IC780_RS14550	COG1056	cytidyltransferase-related domain
IC780_RS14555	COG1024	Enoyl-CoA hydratase
IC780_RS14560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC780_RS14575	COG2814	Major facilitator Superfamily
IC780_RS14580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC780_RS14580	COG0047	phosphoribosylformylglycinamidine synthase activity
IC780_RS14605	COG1473	amidohydrolase
IC780_RS14610	COG0824	Thioesterase
IC780_RS14630	COG0823	Involved in the tonB-independent uptake of proteins
IC780_RS14650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC780_RS14685	COG0628	permease
IC780_RS14695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC780_RS14700	COG0596	Alpha beta hydrolase
IC780_RS14705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC780_RS14705	COG0616	signal peptide processing
IC780_RS14715	COG0658	competence protein
IC780_RS14715	COG2333	competence protein COMEC
IC780_RS14720	COG1136	(ABC) transporter
IC780_RS14725	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC780_RS14760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_RS14780	COG0463	Glycosyl transferase, family 2
IC780_RS14790	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC780_RS14800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_RS14820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC780_RS14825	COG1280	lysine exporter protein (LysE YggA)
IC780_RS14840	COG0019	diaminopimelate decarboxylase activity
IC780_RS14850	COG1113	amino acid transport
IC780_RS14855	COG1115	amino acid carrier protein
IC780_RS14980	COG0681	Belongs to the peptidase S26 family
IC780_RS15015	COG4373	Mu-like prophage FluMu protein gp28
IC780_RS15025	COG4383	Mu-like prophage protein gp29
IC780_RS15030	COG2369	cell adhesion
IC780_RS15050	COG4397	Mu-like prophage major head subunit gpT
IC780_RS15140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC780_RS15145	COG0243	molybdopterin cofactor binding
IC780_RS15150	COG1929	Belongs to the glycerate kinase type-1 family
IC780_RS15165	COG0778	Nitroreductase
IC780_RS15170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_RS15175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_RS15195	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS15200	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC780_RS15205	COG0583	DNA-binding transcription factor activity
IC780_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS15215	COG0596	Alpha beta hydrolase
IC780_RS15220	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_RS15220	COG0596	Alpha beta hydrolase
IC780_RS15225	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_RS15225	COG0596	Alpha beta hydrolase
IC780_RS15230	COG1902	pentaerythritol trinitrate reductase activity
IC780_RS15235	COG1309	transcriptional regulator
IC780_RS15295	COG3811	Belongs to the UPF0386 family
IC780_RS15315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC780_RS15330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_RS15335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_RS15355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC780_RS15360	COG0183	Belongs to the thiolase family
IC780_RS15365	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_RS15370	COG1024	Enoyl-CoA hydratase
IC780_RS15375	COG1960	acyl-CoA dehydrogenase activity
IC780_RS15380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC780_RS15380	COG0644	oxidoreductase
IC780_RS15440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC780_RS15465	COG1002	Type II restriction enzyme, methylase subunits
IC780_RS15470	COG1061	Type III restriction enzyme res subunit
IC780_RS15480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC780_RS15495	COG4372	Transposase
IC780_RS15540	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IC780_RS15560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC780_RS15585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC780_RS15605	COG0741	lytic transglycosylase activity
IC780_RS15625	COG0584	glycerophosphoryl diester phosphodiesterase
IC780_RS15630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_RS15655	COG1597	lipid kinase activity
IC780_RS15670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC780_RS15675	COG0477	Major facilitator Superfamily
IC780_RS15725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC780_RS15730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC780_RS15755	COG0505	Belongs to the CarA family
IC780_RS15775	COG0589	response to stress
IC780_RS15795	COG2321	neutral zinc metallopeptidase
IC780_RS15800	COG2354	Protein conserved in bacteria
IC780_RS15820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_RS15845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC780_RS15850	COG1053	succinate dehydrogenase
IC780_RS15855	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC780_RS15860	COG2009	succinate dehydrogenase
IC780_RS15895	COG2921	Belongs to the UPF0250 family
IC780_RS15900	COG0321	lipoyl(octanoyl) transferase activity
IC780_RS15915	COG0531	amino acid
IC780_RS15925	COG1733	regulation of RNA biosynthetic process
IC780_RS15930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC780_RS15935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC780_RS15935	COG1648	precorrin-2 dehydrogenase activity
IC780_RS15950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC780_RS15980	COG0671	phosphoesterase, PA-phosphatase related
IC780_RS15985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_RS15995	COG1538	Outer membrane efflux protein
IC780_RS16000	COG0393	Putative heavy-metal-binding
IC780_RS16005	COG0393	Putative heavy-metal-binding
IC780_RS16015	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_RS16025	COG0525	valine-tRNA ligase activity
IC780_RS16035	COG0525	valine-tRNA ligase activity
IC780_RS16055	COG0583	DNA-binding transcription factor activity
IC780_RS16060	COG0004	ammonium transporteR
IC780_RS16070	COG0642	Histidine kinase
IC780_RS16075	COG0745	RESPONSE REGULATOR receiver
IC780_RS16080	COG2194	sulfuric ester hydrolase activity
IC780_RS16100	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC780_RS16115	COG2315	Protein conserved in bacteria
IC780_RS16120	COG0142	geranyltranstransferase activity
IC780_RS16125	COG2828	Protein conserved in bacteria
IC780_RS16130	COG1113	amino acid transport
IC780_RS16135	COG2816	NAD+ diphosphatase activity
IC780_RS16140	COG3046	protein related to deoxyribodipyrimidine photolyase
IC780_RS16170	COG2207	Transcriptional regulator
IC780_RS16195	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_RS16215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC780_RS16225	COG1530	ribonuclease E activity
IC780_RS16230	COG0424	maF-like protein
IC780_RS16235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC780_RS16240	COG1792	Involved in formation and maintenance of cell shape
IC780_RS16245	COG1077	Cell shape determining protein MreB Mrl
IC780_RS16250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC780_RS16260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC780_RS16290	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC780_RS16295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC780_RS16300	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC780_RS16305	COG1115	amino acid carrier protein
IC780_RS16325	COG2814	Major facilitator Superfamily
IC780_RS16330	COG1289	transmembrane transporter activity
IC780_RS16380	COG1376	ErfK ybiS ycfS ynhG family protein
IC780_RS16385	COG2832	Protein of unknown function (DUF454)
IC780_RS16410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC780_RS16425	COG0840	transmembrane signaling receptor activity
IC780_RS16465	COG3422	double-strand break repair
IC780_RS16470	COG2824	Alkylphosphonate utilization operon protein PhnA
IC780_RS16475	COG3189	MarR family transcriptional regulator
IC780_RS16480	COG0596	Alpha beta hydrolase
IC780_RS16490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_RS16495	COG1335	isochorismatase
IC780_RS16500	COG0251	oxidation-reduction process
IC780_RS16505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_RS16510	COG2233	PERMEase
IC780_RS16525	COG0354	folic acid binding
IC780_RS16530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC780_RS16540	COG0679	Auxin Efflux Carrier
IC780_RS16545	COG1902	pentaerythritol trinitrate reductase activity
IC780_RS16550	COG4772	TonB-dependent receptor
IC780_RS16555	COG2094	Belongs to the DNA glycosylase MPG family
IC780_RS16580	COG1217	gtp-binding protein TYPA
IC780_RS16585	COG2233	PERMEase
IC780_RS16595	COG0833	amino acid
IC780_RS16600	COG1690	Belongs to the RtcB family
IC780_RS16610	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC780_RS16610	COG2885	chlorophyll binding
IC780_RS16620	COG0183	Belongs to the thiolase family
IC780_RS16635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_RS16655	COG2207	Transcriptional regulator
IC780_RS16660	COG0183	Belongs to the thiolase family
IC780_RS16680	COG2153	protein acetylation
IC780_RS16690	COG1272	protein, Hemolysin III
IC780_RS16695	COG0477	Major facilitator Superfamily
IC780_RS16710	COG0450	alkyl hydroperoxide reductase
IC780_RS16730	COG0285	dihydrofolate synthase activity
IC780_RS16780	COG4206	TonB-dependent receptor
IC780_RS16785	COG2096	Adenosyltransferase
IC780_RS16805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC780_RS16815	COG0745	RESPONSE REGULATOR receiver
IC780_RS16820	COG2205	protein histidine kinase activity
IC780_RS16830	COG1960	acyl-CoA dehydrogenase activity
IC780_RS16835	COG1960	acyl-CoA dehydrogenase activity
IC780_RS16870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC780_RS16910	COG0438	transferase activity, transferring glycosyl groups
IC780_RS16915	COG0463	Glycosyl transferase, family 2
IC780_RS16920	COG0726	polysaccharide deacetylase
IC780_RS16930	COG2194	sulfuric ester hydrolase activity
IC780_RS16945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC780_RS16955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC780_RS16990	COG1862	Preprotein translocase
IC780_RS17000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC780_RS17005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC780_RS17015	COG3781	membrane
IC780_RS17020	COG0613	PHP domain protein
IC780_RS17030	COG2350	Protein conserved in bacteria
IC780_RS17065	COG1607	acyl-coa hydrolase
IC780_RS17090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_RS17125	COG2199	diguanylate cyclase activity
IC780_RS17135	COG1408	metallophosphoesterase
IC780_RS17140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC780_RS17150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC780_RS17170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC780_RS17175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC780_RS17180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC780_RS17185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC780_RS17190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC780_RS17200	COG2969	positive regulation of protein catabolic process
IC780_RS17235	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_RS17235	COG1024	Enoyl-CoA hydratase
IC780_RS17240	COG1960	acyl-CoA dehydrogenase activity
IC780_RS17245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC780_RS17260	COG1309	transcriptional regulator
IC780_RS17265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC780_RS17330	COG1183	phosphatidylcholine synthase activity
IC780_RS17335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC780_RS17365	COG1196	nuclear chromosome segregation
IC780_RS17365	COG0739	heme binding
IC780_RS17365	COG0741	lytic transglycosylase activity
IC780_RS17375	COG1702	phosphate starvation-inducible protein PhoH
IC780_RS17410	COG1295	ribonuclease BN
IC780_RS17420	COG2169	Transcriptional regulator
IC780_RS17425	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC780_RS17470	COG0557	exoribonuclease II activity
IC780_RS17475	COG0339	signal peptide processing
IC780_RS17480	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC780_RS17510	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC780_RS17515	COG1960	acyl-CoA dehydrogenase activity
IC780_RS17565	COG1841	ribosomal large subunit assembly
IC780_RS17650	COG0088	Forms part of the polypeptide exit tunnel
IC780_RS17655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC780_RS17670	COG0626	cystathionine gamma-synthase activity
IC780_RS17675	COG0433	COG0433 Predicted ATPase
IC780_RS17680	COG1017	nitric oxide dioxygenase activity
IC780_RS17680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_RS17685	COG1959	2 iron, 2 sulfur cluster binding
IC780_RS17700	COG1301	dicarboxylic acid transport
IC780_RS17705	COG1946	Acyl-CoA thioesterase
IC780_RS17710	COG2937	Belongs to the GPAT DAPAT family
IC780_RS17725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC780_RS17730	COG1040	competence protein
IC780_RS17735	COG0494	nUDIX hydrolase
IC780_RS17745	COG0598	Magnesium transport protein CorA
IC780_RS17755	COG2854	intermembrane phospholipid transfer
IC780_RS17765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC780_RS17770	COG1127	ABC transporter
IC780_RS17775	COG0513	Belongs to the DEAD box helicase family
IC780_RS17795	COG0408	coproporphyrinogen oxidase activity
IC780_RS17810	COG1960	acyl-CoA dehydrogenase activity
IC780_RS17820	COG1983	PspC domain protein
IC780_RS17825	COG0517	IMP dehydrogenase activity
IC780_RS17825	COG0617	tRNA 3'-terminal CCA addition
IC780_RS17825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC780_RS17850	COG0752	glycyl-tRNA synthetase alpha subunit
IC780_RS17870	COG0583	DNA-binding transcription factor activity
IC780_RS17875	COG1794	racemase activity, acting on amino acids and derivatives
IC780_RS17880	COG0583	DNA-binding transcription factor activity
IC780_RS17920	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS17930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC780_RS17935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC780_RS17940	COG0833	amino acid
IC780_RS17945	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS17975	COG1192	Involved in chromosome partitioning
IC780_RS17980	COG0628	permease
IC780_RS17990	COG1289	transmembrane transporter activity
IC780_RS18005	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_RS18010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC780_RS18020	COG0277	FAD linked oxidase domain protein
IC780_RS18025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC780_RS18030	COG5006	permease, DMT superfamily
IC780_RS18050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC780_RS18055	COG5380	lipid catabolic process
IC780_RS18065	COG0335	large ribosomal subunit rRNA binding
IC780_RS18075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC780_RS18090	COG4969	Belongs to the N-Me-Phe pilin family
IC780_RS18115	COG4969	Belongs to the N-Me-Phe pilin family
IC780_RS18130	COG0194	GDP metabolic process
IC780_RS18145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC780_RS18165	COG3307	-O-antigen
IC780_RS18175	COG4969	Belongs to the N-Me-Phe pilin family
IC780_RS18185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC780_RS18190	COG1704	LemA family
IC780_RS18200	COG0493	'glutamate synthase
IC780_RS18205	COG0070	glutamate synthase
IC780_RS18205	COG0069	glutamate synthase activity
IC780_RS18205	COG0067	glutamate synthase
IC780_RS18255	COG2226	methyltransferase
IC780_RS18270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC780_RS18275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC780_RS18320	COG0833	amino acid
IC780_RS18395	COG0488	(ABC) transporter
IC780_RS18400	COG0028	Belongs to the TPP enzyme family
IC780_RS18410	COG4221	oxidoreductase activity
IC780_RS18415	COG0659	secondary active sulfate transmembrane transporter activity
IC780_RS18445	COG0427	acetyl-CoA hydrolase
IC780_RS18475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC780_RS18520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC780_RS18585	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_RS18590	COG1733	regulation of RNA biosynthetic process
IC780_RS18620	COG1733	regulation of RNA biosynthetic process
IC780_RS18640	COG0667	Aldo Keto reductase
IC780_RS18660	COG0583	DNA-binding transcription factor activity
IC780_RS18665	COG2814	Major facilitator Superfamily
IC780_RS18700	COG1335	isochorismatase
IC780_RS18710	COG1012	belongs to the aldehyde dehydrogenase family
IC780_RS18715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC780_RS18725	COG1113	amino acid transport
IC780_RS18735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC780_RS18785	COG2814	Major facilitator Superfamily
IC780_RS18795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC780_RS18795	COG0352	thiamine-phosphate diphosphorylase activity
IC780_RS18795	COG0351	phosphomethylpyrimidine kinase
IC780_RS18805	COG4221	oxidoreductase activity
IC780_RS18825	COG1309	transcriptional regulator
IC780_RS18845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC780_RS18855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC780_RS18860	COG3162	membrane
IC780_RS18865	COG2205	protein histidine kinase activity
IC780_RS18865	COG2198	Histidine kinase
IC780_RS18865	COG0784	Response regulator, receiver
IC780_RS18890	COG1522	sequence-specific DNA binding
IC780_RS18895	COG1335	isochorismatase
IC780_RS18900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC780_RS18910	COG0668	transmembrane transport
IC780_RS18915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC780_RS18920	COG1519	Transferase
IC780_RS18925	COG1902	pentaerythritol trinitrate reductase activity
IC780_RS18945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC780_RS18970	COG0426	domain, Protein
IC780_RS18970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_RS18975	COG2119	membrane
IC780_RS18985	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_RS18995	COG4942	peptidase
IC780_RS19010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC780_RS19020	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC780_RS19040	COG0189	ligase activity
IC780_RS19065	COG0708	Exodeoxyribonuclease III
IC780_RS19070	COG1393	Belongs to the ArsC family
IC780_RS19085	COG3706	GGDEF domain
IC780_RS19100	COG0666	response to abiotic stimulus
IC780_RS19100	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC780_RS19120	COG2351	hydroxyisourate hydrolase activity
IC780_RS19125	COG2233	PERMEase
IC780_RS19135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_RS19145	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC780_RS19155	COG3150	esterase
IC780_RS19195	COG1388	LysM domain
IC780_RS19195	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC780_RS19210	COG2918	glutathione biosynthetic process
IC780_RS19225	COG2733	membrane
IC780_RS19230	COG0436	Aminotransferase
IC780_RS19235	COG0534	Mate efflux family protein
IC780_RS19330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC780_RS19335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC780_RS19345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC780_RS19380	COG1280	lysine exporter protein (LysE YggA)
IC780_RS19385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC780_RS19390	COG0546	phosphoglycolate phosphatase activity
IC780_RS19400	COG0010	Belongs to the arginase family
IC780_RS19430	COG2188	Transcriptional regulator
IC780_RS19440	COG0523	cobalamin synthesis protein
IC780_RS19450	COG1113	amino acid transport
IC780_RS19460	COG0625	glutathione transferase activity
IC780_RS19465	COG0346	lactoylglutathione lyase activity
IC780_RS19480	COG1683	Conserved Protein
IC780_RS19485	COG0534	Mate efflux family protein
IC780_RS19490	COG0385	Bile acid
IC780_RS19495	COG1335	isochorismatase
IC780_RS19500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC780_RS19520	COG2116	formate transmembrane transporter activity
IC780_RS19525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC780_RS19530	COG2133	pyrroloquinoline quinone binding
IC780_RS19535	COG2983	Belongs to the UPF0260 family
IC780_RS19540	COG5487	UPF0391 membrane protein
IC780_RS19555	COG1194	a g-specific adenine glycosylase
IC780_RS19570	COG2818	Glycosylase
IC780_RS19575	COG1064	alcohol dehydrogenase
IC780_RS19595	COG0583	DNA-binding transcription factor activity
IC780_RS19600	COG0656	L-ascorbic acid biosynthetic process
IC780_RS19605	COG2814	Major facilitator Superfamily
IC780_RS19640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_RS19655	COG2233	PERMEase
IC780_RS19695	COG0733	neurotransmitter:sodium symporter activity
IC780_RS19705	COG0625	glutathione transferase activity
IC780_RS19735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC780_RS19740	COG0657	acetylesterase activity
IC780_RS19790	COG2951	lytic endotransglycosylase activity
IC780_RS19795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC780_RS19810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC780_RS19820	COG0671	phosphoesterase, PA-phosphatase related
IC780_RS19825	COG0861	Integral membrane protein TerC family
IC780_RS19835	COG0754	glutathionylspermidine amidase activity
IC780_RS19845	COG0402	S-adenosylhomocysteine deaminase activity
IC780_RS19860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC780_RS19915	COG4372	Transposase
IC780_RS19940	COG0589	response to stress
IC780_RS19945	COG0659	secondary active sulfate transmembrane transporter activity
IC780_RS19975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC780_RS20080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC780_RS20155	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS20165	COG2826	transposase and inactivated derivatives, IS30 family
IC780_RS20265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC780_RS20315	COG1192	Involved in chromosome partitioning
IC780_RS20330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC780_RS20365	COG0739	heme binding
IC780_RS20545	COG0501	Belongs to the peptidase M48B family
IC780_RS20645	COG2217	Heavy metal translocating P-type atpase
IC780_RS20655	COG2205	protein histidine kinase activity
IC780_RS20670	COG2132	Multicopper oxidase
IC780_RS20695	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_RS20735	COG0789	Transcriptional regulator
IC780_RS20890	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC780_RS20925	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC780_RS20930	COG0659	secondary active sulfate transmembrane transporter activity
IC780_RS20945	COG3328	transposase activity
IC780_RS20950	COG0583	DNA-binding transcription factor activity
IC780_RS20955	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC780_RS20960	COG3321	synthase
IC780_RS20960	COG0604	alcohol dehydrogenase
IC780_RS20970	COG0697	spore germination
IC780_RS20975	COG0477	Major facilitator Superfamily
IC780_RS21005	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC780_RS21020	COG1979	alcohol dehydrogenase
IC780_RS21030	COG1902	pentaerythritol trinitrate reductase activity
IC780_RS21040	COG1309	transcriptional regulator
IC780_RS21045	COG2130	NADP-dependent
IC780_RS21060	COG0582	viral genome integration into host DNA
IC780_RS21105	COG0210	DNA helicase
IC780_RS21125	COG0210	DNA helicase
IC780_RS21185	COG1525	nuclease
IC780_RS21270	COG1475	DNA binding
IC780_RS21285	COG3853	Toxic anion resistance protein (TelA)
IC780_RS21465	COG0741	lytic transglycosylase activity
IC780_RS21500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process