locus-tag	class	description
IC785_RS00010	COG0592	DNA-directed DNA polymerase activity
IC785_RS00020	COG0187	DNA topoisomerase II activity
IC785_RS00030	COG0586	Pfam SNARE associated Golgi protein
IC785_RS00035	COG0488	(ABC) transporter
IC785_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC785_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC785_RS00100	COG0625	glutathione transferase activity
IC785_RS00110	COG0733	neurotransmitter:sodium symporter activity
IC785_RS00150	COG2233	PERMEase
IC785_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS00200	COG2814	Major facilitator Superfamily
IC785_RS00205	COG0656	L-ascorbic acid biosynthetic process
IC785_RS00210	COG0583	DNA-binding transcription factor activity
IC785_RS00230	COG1064	alcohol dehydrogenase
IC785_RS00235	COG2818	Glycosylase
IC785_RS00250	COG1194	a g-specific adenine glycosylase
IC785_RS00265	COG5487	UPF0391 membrane protein
IC785_RS00270	COG2983	Belongs to the UPF0260 family
IC785_RS00275	COG2133	pyrroloquinoline quinone binding
IC785_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC785_RS00285	COG2116	formate transmembrane transporter activity
IC785_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC785_RS00310	COG1335	isochorismatase
IC785_RS00315	COG0385	Bile acid
IC785_RS00320	COG0534	Mate efflux family protein
IC785_RS00325	COG1683	Conserved Protein
IC785_RS00340	COG0346	lactoylglutathione lyase activity
IC785_RS00345	COG0625	glutathione transferase activity
IC785_RS00355	COG1113	amino acid transport
IC785_RS00365	COG0523	cobalamin synthesis protein
IC785_RS00375	COG2188	Transcriptional regulator
IC785_RS00405	COG0010	Belongs to the arginase family
IC785_RS00415	COG0546	phosphoglycolate phosphatase activity
IC785_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC785_RS00425	COG1280	lysine exporter protein (LysE YggA)
IC785_RS00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC785_RS00465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC785_RS00470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC785_RS00565	COG0534	Mate efflux family protein
IC785_RS00570	COG0436	Aminotransferase
IC785_RS00575	COG2733	membrane
IC785_RS00590	COG2918	glutathione biosynthetic process
IC785_RS00605	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC785_RS00605	COG1388	LysM domain
IC785_RS00625	COG4372	Transposase
IC785_RS00670	COG3150	esterase
IC785_RS00680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC785_RS00690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC785_RS00700	COG2233	PERMEase
IC785_RS00705	COG2351	hydroxyisourate hydrolase activity
IC785_RS00725	COG0666	response to abiotic stimulus
IC785_RS00725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC785_RS00740	COG3706	GGDEF domain
IC785_RS00755	COG1393	Belongs to the ArsC family
IC785_RS00760	COG0708	Exodeoxyribonuclease III
IC785_RS00785	COG0189	ligase activity
IC785_RS00805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC785_RS00815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC785_RS00830	COG4942	peptidase
IC785_RS00840	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC785_RS00850	COG2119	membrane
IC785_RS00855	COG0426	domain, Protein
IC785_RS00855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC785_RS00880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC785_RS00900	COG1902	pentaerythritol trinitrate reductase activity
IC785_RS00905	COG1519	Transferase
IC785_RS00910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC785_RS00915	COG0668	transmembrane transport
IC785_RS00925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC785_RS00930	COG1335	isochorismatase
IC785_RS00935	COG1522	sequence-specific DNA binding
IC785_RS00960	COG2198	Histidine kinase
IC785_RS00960	COG0784	Response regulator, receiver
IC785_RS00960	COG2205	protein histidine kinase activity
IC785_RS00965	COG3162	membrane
IC785_RS00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC785_RS00980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC785_RS01000	COG1309	transcriptional regulator
IC785_RS01020	COG4221	oxidoreductase activity
IC785_RS01030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC785_RS01030	COG0351	phosphomethylpyrimidine kinase
IC785_RS01030	COG0352	thiamine-phosphate diphosphorylase activity
IC785_RS01040	COG2814	Major facilitator Superfamily
IC785_RS01075	COG0154	amidase activity
IC785_RS01120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC785_RS01130	COG1113	amino acid transport
IC785_RS01140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC785_RS01145	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS01155	COG1335	isochorismatase
IC785_RS01190	COG2814	Major facilitator Superfamily
IC785_RS01195	COG0583	DNA-binding transcription factor activity
IC785_RS01215	COG0667	Aldo Keto reductase
IC785_RS01235	COG1733	regulation of RNA biosynthetic process
IC785_RS01265	COG1733	regulation of RNA biosynthetic process
IC785_RS01270	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC785_RS01335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC785_RS01380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC785_RS01410	COG0427	acetyl-CoA hydrolase
IC785_RS01440	COG0659	secondary active sulfate transmembrane transporter activity
IC785_RS01445	COG4221	oxidoreductase activity
IC785_RS01455	COG0028	Belongs to the TPP enzyme family
IC785_RS01460	COG0488	(ABC) transporter
IC785_RS01530	COG0833	amino acid
IC785_RS01575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC785_RS01580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC785_RS01595	COG2226	methyltransferase
IC785_RS01645	COG0069	glutamate synthase activity
IC785_RS01645	COG0067	glutamate synthase
IC785_RS01645	COG0070	glutamate synthase
IC785_RS01650	COG0493	'glutamate synthase
IC785_RS01660	COG1704	LemA family
IC785_RS01665	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC785_RS01675	COG4969	Belongs to the N-Me-Phe pilin family
IC785_RS01685	COG3307	-O-antigen
IC785_RS01705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC785_RS01720	COG0194	GDP metabolic process
IC785_RS01735	COG4969	Belongs to the N-Me-Phe pilin family
IC785_RS01760	COG4969	Belongs to the N-Me-Phe pilin family
IC785_RS01775	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC785_RS01785	COG0335	large ribosomal subunit rRNA binding
IC785_RS01795	COG5380	lipid catabolic process
IC785_RS01800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC785_RS01820	COG5006	permease, DMT superfamily
IC785_RS01825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC785_RS01830	COG0277	FAD linked oxidase domain protein
IC785_RS01840	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC785_RS01845	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC785_RS01860	COG1289	transmembrane transporter activity
IC785_RS01870	COG0628	permease
IC785_RS01875	COG1192	Involved in chromosome partitioning
IC785_RS01905	COG0833	amino acid
IC785_RS01910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC785_RS01915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC785_RS01925	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS01965	COG0583	DNA-binding transcription factor activity
IC785_RS01970	COG1794	racemase activity, acting on amino acids and derivatives
IC785_RS01975	COG0583	DNA-binding transcription factor activity
IC785_RS01995	COG0752	glycyl-tRNA synthetase alpha subunit
IC785_RS02020	COG0517	IMP dehydrogenase activity
IC785_RS02020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC785_RS02020	COG0617	tRNA 3'-terminal CCA addition
IC785_RS02025	COG1983	PspC domain protein
IC785_RS02035	COG1960	acyl-CoA dehydrogenase activity
IC785_RS02050	COG0408	coproporphyrinogen oxidase activity
IC785_RS02070	COG0513	Belongs to the DEAD box helicase family
IC785_RS02075	COG1127	ABC transporter
IC785_RS02080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC785_RS02090	COG2854	intermembrane phospholipid transfer
IC785_RS02100	COG0598	Magnesium transport protein CorA
IC785_RS02110	COG0494	nUDIX hydrolase
IC785_RS02115	COG1040	competence protein
IC785_RS02120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC785_RS02135	COG2937	Belongs to the GPAT DAPAT family
IC785_RS02140	COG1946	Acyl-CoA thioesterase
IC785_RS02145	COG1301	dicarboxylic acid transport
IC785_RS02160	COG1959	2 iron, 2 sulfur cluster binding
IC785_RS02165	COG1017	nitric oxide dioxygenase activity
IC785_RS02165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC785_RS02170	COG0433	COG0433 Predicted ATPase
IC785_RS02175	COG0626	cystathionine gamma-synthase activity
IC785_RS02190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC785_RS02195	COG0088	Forms part of the polypeptide exit tunnel
IC785_RS02330	COG1960	acyl-CoA dehydrogenase activity
IC785_RS02335	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC785_RS02365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC785_RS02370	COG0339	signal peptide processing
IC785_RS02375	COG0557	exoribonuclease II activity
IC785_RS02420	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC785_RS02425	COG2169	Transcriptional regulator
IC785_RS02435	COG1295	ribonuclease BN
IC785_RS02470	COG1702	phosphate starvation-inducible protein PhoH
IC785_RS02480	COG0739	heme binding
IC785_RS02480	COG0741	lytic transglycosylase activity
IC785_RS02480	COG1196	nuclear chromosome segregation
IC785_RS02510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC785_RS02515	COG1183	phosphatidylcholine synthase activity
IC785_RS02580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC785_RS02585	COG1309	transcriptional regulator
IC785_RS02600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC785_RS02605	COG1960	acyl-CoA dehydrogenase activity
IC785_RS02610	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC785_RS02610	COG1024	Enoyl-CoA hydratase
IC785_RS02645	COG2969	positive regulation of protein catabolic process
IC785_RS02655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC785_RS02660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC785_RS02665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC785_RS02670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC785_RS02675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC785_RS02695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC785_RS02705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC785_RS02710	COG1408	metallophosphoesterase
IC785_RS02720	COG2199	diguanylate cyclase activity
IC785_RS02755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC785_RS02780	COG1607	acyl-coa hydrolase
IC785_RS02815	COG2350	Protein conserved in bacteria
IC785_RS02825	COG0613	PHP domain protein
IC785_RS02830	COG3781	membrane
IC785_RS02840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC785_RS02845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC785_RS02855	COG1862	Preprotein translocase
IC785_RS02890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC785_RS02915	COG2194	sulfuric ester hydrolase activity
IC785_RS02925	COG0726	polysaccharide deacetylase
IC785_RS02930	COG0463	Glycosyl transferase, family 2
IC785_RS02935	COG0438	transferase activity, transferring glycosyl groups
IC785_RS02975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC785_RS03010	COG1960	acyl-CoA dehydrogenase activity
IC785_RS03015	COG1960	acyl-CoA dehydrogenase activity
IC785_RS03025	COG2205	protein histidine kinase activity
IC785_RS03030	COG0745	RESPONSE REGULATOR receiver
IC785_RS03040	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC785_RS03060	COG2096	Adenosyltransferase
IC785_RS03065	COG4206	TonB-dependent receptor
IC785_RS03115	COG0285	dihydrofolate synthase activity
IC785_RS03135	COG0450	alkyl hydroperoxide reductase
IC785_RS03150	COG0477	Major facilitator Superfamily
IC785_RS03155	COG1272	protein, Hemolysin III
IC785_RS03165	COG2153	protein acetylation
IC785_RS03185	COG0183	Belongs to the thiolase family
IC785_RS03190	COG2207	Transcriptional regulator
IC785_RS03210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC785_RS03235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC785_RS03235	COG2885	chlorophyll binding
IC785_RS03245	COG1690	Belongs to the RtcB family
IC785_RS03250	COG0833	amino acid
IC785_RS03260	COG2233	PERMEase
IC785_RS03265	COG1217	gtp-binding protein TYPA
IC785_RS03290	COG2094	Belongs to the DNA glycosylase MPG family
IC785_RS03295	COG4772	TonB-dependent receptor
IC785_RS03300	COG1902	pentaerythritol trinitrate reductase activity
IC785_RS03305	COG0679	Auxin Efflux Carrier
IC785_RS03315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC785_RS03320	COG0354	folic acid binding
IC785_RS03335	COG2233	PERMEase
IC785_RS03340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC785_RS03345	COG0251	oxidation-reduction process
IC785_RS03350	COG1335	isochorismatase
IC785_RS03355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC785_RS03365	COG0596	Alpha beta hydrolase
IC785_RS03370	COG3189	MarR family transcriptional regulator
IC785_RS03375	COG2824	Alkylphosphonate utilization operon protein PhnA
IC785_RS03380	COG3422	double-strand break repair
IC785_RS03420	COG0840	transmembrane signaling receptor activity
IC785_RS03435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC785_RS03460	COG2832	Protein of unknown function (DUF454)
IC785_RS03465	COG1376	ErfK ybiS ycfS ynhG family protein
IC785_RS03515	COG1289	transmembrane transporter activity
IC785_RS03520	COG2814	Major facilitator Superfamily
IC785_RS03540	COG1115	amino acid carrier protein
IC785_RS03545	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC785_RS03550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC785_RS03555	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC785_RS03585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC785_RS03595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC785_RS03600	COG1077	Cell shape determining protein MreB Mrl
IC785_RS03605	COG1792	Involved in formation and maintenance of cell shape
IC785_RS03610	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC785_RS03615	COG0424	maF-like protein
IC785_RS03620	COG1530	ribonuclease E activity
IC785_RS03630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC785_RS03650	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC785_RS03675	COG2207	Transcriptional regulator
IC785_RS03705	COG3046	protein related to deoxyribodipyrimidine photolyase
IC785_RS03710	COG2816	NAD+ diphosphatase activity
IC785_RS03715	COG1113	amino acid transport
IC785_RS03720	COG2828	Protein conserved in bacteria
IC785_RS03725	COG0142	geranyltranstransferase activity
IC785_RS03730	COG2315	Protein conserved in bacteria
IC785_RS03745	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC785_RS03765	COG2194	sulfuric ester hydrolase activity
IC785_RS03770	COG0745	RESPONSE REGULATOR receiver
IC785_RS03775	COG0642	Histidine kinase
IC785_RS03785	COG0004	ammonium transporteR
IC785_RS03790	COG0583	DNA-binding transcription factor activity
IC785_RS03810	COG0525	valine-tRNA ligase activity
IC785_RS03820	COG0525	valine-tRNA ligase activity
IC785_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS03840	COG0393	Putative heavy-metal-binding
IC785_RS03845	COG0393	Putative heavy-metal-binding
IC785_RS03850	COG1538	Outer membrane efflux protein
IC785_RS03860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS03865	COG0671	phosphoesterase, PA-phosphatase related
IC785_RS03895	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC785_RS03910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC785_RS03910	COG1648	precorrin-2 dehydrogenase activity
IC785_RS03915	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC785_RS03920	COG1733	regulation of RNA biosynthetic process
IC785_RS03930	COG0531	amino acid
IC785_RS03945	COG0321	lipoyl(octanoyl) transferase activity
IC785_RS03950	COG2921	Belongs to the UPF0250 family
IC785_RS03985	COG2009	succinate dehydrogenase
IC785_RS03990	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC785_RS03995	COG1053	succinate dehydrogenase
IC785_RS04000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC785_RS04025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC785_RS04045	COG2354	Protein conserved in bacteria
IC785_RS04050	COG2321	neutral zinc metallopeptidase
IC785_RS04070	COG0589	response to stress
IC785_RS04090	COG0505	Belongs to the CarA family
IC785_RS04115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC785_RS04120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC785_RS04170	COG0477	Major facilitator Superfamily
IC785_RS04175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC785_RS04190	COG1597	lipid kinase activity
IC785_RS04195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IC785_RS04215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC785_RS04220	COG0584	glycerophosphoryl diester phosphodiesterase
IC785_RS04240	COG0741	lytic transglycosylase activity
IC785_RS04260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC785_RS04265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC785_RS04325	COG0644	oxidoreductase
IC785_RS04325	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC785_RS04330	COG1960	acyl-CoA dehydrogenase activity
IC785_RS04335	COG1024	Enoyl-CoA hydratase
IC785_RS04340	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC785_RS04345	COG0183	Belongs to the thiolase family
IC785_RS04350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC785_RS04370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS04375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC785_RS04390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC785_RS04410	COG3811	Belongs to the UPF0386 family
IC785_RS04475	COG1309	transcriptional regulator
IC785_RS04480	COG1902	pentaerythritol trinitrate reductase activity
IC785_RS04485	COG0596	Alpha beta hydrolase
IC785_RS04485	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC785_RS04490	COG0596	Alpha beta hydrolase
IC785_RS04490	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC785_RS04495	COG0596	Alpha beta hydrolase
IC785_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS04505	COG0583	DNA-binding transcription factor activity
IC785_RS04510	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC785_RS04515	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS04535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS04540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC785_RS04545	COG0778	Nitroreductase
IC785_RS04560	COG1929	Belongs to the glycerate kinase type-1 family
IC785_RS04565	COG0243	molybdopterin cofactor binding
IC785_RS04570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC785_RS04575	COG3339	Conserved Protein
IC785_RS04600	COG1115	amino acid carrier protein
IC785_RS04605	COG1113	amino acid transport
IC785_RS04615	COG0019	diaminopimelate decarboxylase activity
IC785_RS04630	COG1280	lysine exporter protein (LysE YggA)
IC785_RS04635	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC785_RS04655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC785_RS04665	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC785_RS04675	COG0463	Glycosyl transferase, family 2
IC785_RS04695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS04730	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC785_RS04735	COG1136	(ABC) transporter
IC785_RS04740	COG2333	competence protein COMEC
IC785_RS04740	COG0658	competence protein
IC785_RS04750	COG0616	signal peptide processing
IC785_RS04750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC785_RS04755	COG0596	Alpha beta hydrolase
IC785_RS04760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC785_RS04770	COG0628	permease
IC785_RS04805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC785_RS04825	COG0823	Involved in the tonB-independent uptake of proteins
IC785_RS04845	COG0824	Thioesterase
IC785_RS04850	COG1473	amidohydrolase
IC785_RS04875	COG0047	phosphoribosylformylglycinamidine synthase activity
IC785_RS04875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC785_RS04880	COG2814	Major facilitator Superfamily
IC785_RS04895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC785_RS04900	COG1024	Enoyl-CoA hydratase
IC785_RS04905	COG1051	belongs to the nudix hydrolase family
IC785_RS04905	COG1056	cytidyltransferase-related domain
IC785_RS04920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC785_RS04935	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC785_RS04940	COG0602	queuosine metabolic process
IC785_RS04950	COG4625	pathogenesis
IC785_RS04955	COG0583	DNA-binding transcription factor activity
IC785_RS04960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC785_RS04965	COG4208	sulfate ABC transporter
IC785_RS04970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC785_RS04980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC785_RS04985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC785_RS04990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC785_RS05010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC785_RS05020	COG0481	GTPase activity
IC785_RS05025	COG0681	Belongs to the peptidase S26 family
IC785_RS05040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC785_RS05050	COG1381	Involved in DNA repair and RecF pathway recombination
IC785_RS05055	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC785_RS05065	COG4221	oxidoreductase activity
IC785_RS05090	COG0436	Aminotransferase
IC785_RS05110	COG3706	GGDEF domain
IC785_RS05115	COG0556	nucleotide-excision repair
IC785_RS05170	COG2070	2-Nitropropane dioxygenase
IC785_RS05185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC785_RS05200	COG1215	transferase activity, transferring glycosyl groups
IC785_RS05215	COG0415	Belongs to the DNA photolyase family
IC785_RS05225	COG1252	NADH dehydrogenase
IC785_RS05230	COG1686	Belongs to the peptidase S11 family
IC785_RS05245	COG1187	pseudouridine synthase activity
IC785_RS05435	COG5484	DNA packaging
IC785_RS05435	COG3728	DNA packaging
IC785_RS05525	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS05580	COG4372	Transposase
IC785_RS05895	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS05920	COG1196	nuclear chromosome segregation
IC785_RS05920	COG0739	heme binding
IC785_RS05920	COG0741	lytic transglycosylase activity
IC785_RS06015	COG0477	Major facilitator Superfamily
IC785_RS06020	COG0583	DNA-binding transcription factor activity
IC785_RS06025	COG1823	symporter activity
IC785_RS06035	COG0612	Peptidase, M16
IC785_RS06060	COG0352	thiamine-phosphate diphosphorylase activity
IC785_RS06095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC785_RS06120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC785_RS06125	COG0076	glutamate decarboxylase activity
IC785_RS06135	COG1522	sequence-specific DNA binding
IC785_RS06140	COG3961	Belongs to the TPP enzyme family
IC785_RS06145	COG1113	amino acid transport
IC785_RS06150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC785_RS06155	COG0573	inorganic phosphate transmembrane transporter activity
IC785_RS06165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC785_RS06170	COG0616	signal peptide processing
IC785_RS06185	COG3647	Membrane
IC785_RS06210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC785_RS06215	COG1686	Belongs to the peptidase S11 family
IC785_RS06240	COG0583	DNA-binding transcription factor activity
IC785_RS06245	COG1067	ATP-dependent peptidase activity
IC785_RS06270	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC785_RS06285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC785_RS06290	COG1966	Carbon starvation protein
IC785_RS06295	COG2879	small protein
IC785_RS06325	COG2814	Major facilitator Superfamily
IC785_RS06365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC785_RS06370	COG2423	ornithine cyclodeaminase activity
IC785_RS06380	COG2964	Protein conserved in bacteria
IC785_RS06385	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC785_RS06385	COG2755	lipolytic protein G-D-S-L family
IC785_RS06390	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS06395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC785_RS06405	COG1741	Belongs to the pirin family
IC785_RS06420	COG3739	integral membrane protein
IC785_RS06440	COG0302	gtp cyclohydrolase
IC785_RS06450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC785_RS06460	COG2840	Smr protein MutS2
IC785_RS06475	COG0512	Glutamine amidotransferase of anthranilate synthase
IC785_RS06490	COG0174	glutamine synthetase
IC785_RS06500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC785_RS06535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC785_RS06540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC785_RS06545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC785_RS06565	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS06575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC785_RS06580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC785_RS06585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC785_RS06600	COG1960	acyl-CoA dehydrogenase activity
IC785_RS06605	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC785_RS06610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC785_RS06620	COG2223	nitrite transmembrane transporter activity
IC785_RS06630	COG0024	Methionine aminopeptidase
IC785_RS06635	COG0052	Belongs to the universal ribosomal protein uS2 family
IC785_RS06650	COG2207	Transcriptional regulator
IC785_RS06675	COG2951	lytic endotransglycosylase activity
IC785_RS06680	COG0772	Belongs to the SEDS family
IC785_RS06695	COG0842	Transport permease protein
IC785_RS06700	COG1131	(ABC) transporter
IC785_RS06705	COG0582	viral genome integration into host DNA
IC785_RS06980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IC785_RS07035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS07050	COG4215	(ABC) transporter
IC785_RS07055	COG4160	amino acid transport
IC785_RS07060	COG4598	ABC transporter
IC785_RS07070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC785_RS07075	COG0826	peptidase U32
IC785_RS07080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC785_RS07085	COG0384	phenazine biosynthesis protein PhzF
IC785_RS07095	COG1720	tRNA m6t6A37 methyltransferase activity
IC785_RS07105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC785_RS07120	COG0642	Histidine kinase
IC785_RS07140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC785_RS07145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC785_RS07150	COG3139	Protein of unknown function (DUF1315)
IC785_RS07160	COG1301	dicarboxylic acid transport
IC785_RS07165	COG1960	acyl-CoA dehydrogenase activity
IC785_RS07185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC785_RS07195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC785_RS07200	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC785_RS07220	COG1690	Belongs to the RtcB family
IC785_RS07225	COG1234	tRNA 3'-trailer cleavage
IC785_RS07230	COG4650	regulator
IC785_RS07255	COG2363	Small membrane protein
IC785_RS07275	COG0513	Belongs to the DEAD box helicase family
IC785_RS07285	COG0778	Nitroreductase
IC785_RS07345	COG1610	YqeY-like protein
IC785_RS07375	COG0515	serine threonine protein kinase
IC785_RS07375	COG2815	serine threonine protein kinase
IC785_RS07480	COG1335	isochorismatase
IC785_RS07485	COG0583	DNA-binding transcription factor activity
IC785_RS07505	COG0596	Alpha beta hydrolase
IC785_RS07515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC785_RS07525	COG0786	glutamate:sodium symporter activity
IC785_RS07530	COG0475	glutathione-regulated potassium exporter activity
IC785_RS07530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC785_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS07610	COG1309	transcriptional regulator
IC785_RS07620	COG2169	Transcriptional regulator
IC785_RS07620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC785_RS07635	COG2985	domain, Protein
IC785_RS07660	COG2995	paraquat-inducible protein a
IC785_RS07665	COG3008	intermembrane lipid transfer
IC785_RS07665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC785_RS07675	COG2351	hydroxyisourate hydrolase activity
IC785_RS07690	COG5002	protein histidine kinase activity
IC785_RS07715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC785_RS07725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC785_RS07730	COG0642	Histidine kinase
IC785_RS07735	COG0745	RESPONSE REGULATOR receiver
IC785_RS07760	COG2175	clavaminate synthase activity
IC785_RS07765	COG3246	L-lysine catabolic process to acetate
IC785_RS07770	COG2814	Major facilitator Superfamily
IC785_RS07785	COG2855	membrane
IC785_RS07830	COG1301	dicarboxylic acid transport
IC785_RS07845	COG2011	ABC-type metal ion transport system permease component
IC785_RS07850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC785_RS07855	COG1464	Belongs to the NlpA lipoprotein family
IC785_RS07860	COG0151	Belongs to the GarS family
IC785_RS07865	COG0138	bifunctional purine biosynthesis protein purh
IC785_RS07870	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC785_RS07900	COG2308	Evidence 4 Homologs of previously reported genes of
IC785_RS07910	COG1305	Transglutaminase-like
IC785_RS07920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC785_RS07925	COG0305	Participates in initiation and elongation during chromosome replication
IC785_RS07950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC785_RS07960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC785_RS07990	COG1649	PFAM Uncharacterised BCR, COG1649
IC785_RS07990	COG0726	polysaccharide deacetylase
IC785_RS07995	COG1215	transferase activity, transferring glycosyl groups
IC785_RS08000	COG3658	cytochrome
IC785_RS08010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC785_RS08030	COG2890	protein-(glutamine-N5) methyltransferase activity
IC785_RS08035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC785_RS08040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC785_RS08055	COG1960	acyl-CoA dehydrogenase activity
IC785_RS08060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC785_RS08065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC785_RS08090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC785_RS08095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC785_RS08100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC785_RS08105	COG2205	protein histidine kinase activity
IC785_RS08110	COG0745	RESPONSE REGULATOR receiver
IC785_RS08115	COG0174	glutamine synthetase
IC785_RS08135	COG0729	surface antigen
IC785_RS08165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC785_RS08170	COG2814	Major facilitator Superfamily
IC785_RS08180	COG0583	DNA-binding transcription factor activity
IC785_RS08195	COG1187	pseudouridine synthase activity
IC785_RS08215	COG0802	atpase or kinase
IC785_RS08220	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC785_RS08230	COG1923	regulation of RNA biosynthetic process
IC785_RS08260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC785_RS08265	COG0519	Catalyzes the synthesis of GMP from XMP
IC785_RS08265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC785_RS08270	COG4302	ethanolamine ammonia-lyase activity
IC785_RS08275	COG4303	Ethanolamine ammonia lyase large subunit
IC785_RS08280	COG0531	amino acid
IC785_RS08300	COG1454	alcohol dehydrogenase
IC785_RS08305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC785_RS08315	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC785_RS08335	COG0308	aminopeptidase N
IC785_RS08365	COG0625	glutathione transferase activity
IC785_RS08425	COG4264	IucA IucC family
IC785_RS08435	COG4264	IucA IucC family
IC785_RS08440	COG2423	ornithine cyclodeaminase activity
IC785_RS08445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC785_RS08455	COG0668	transmembrane transport
IC785_RS08500	COG0488	(ABC) transporter
IC785_RS08505	COG0589	response to stress
IC785_RS08530	COG3135	benzoate transporter
IC785_RS08535	COG1522	sequence-specific DNA binding
IC785_RS08545	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS08555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC785_RS08560	COG0583	DNA-binding transcription factor activity
IC785_RS08570	COG0183	Belongs to the thiolase family
IC785_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS08580	COG2030	dehydratase
IC785_RS08585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC785_RS08610	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC785_RS08620	COG0824	Thioesterase
IC785_RS08625	COG1454	alcohol dehydrogenase
IC785_RS08635	COG1335	isochorismatase
IC785_RS08650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC785_RS08680	COG0069	glutamate synthase activity
IC785_RS08720	COG2814	Major facilitator Superfamily
IC785_RS08735	COG0511	ligase activity, forming carbon-carbon bonds
IC785_RS08755	COG1116	anion transmembrane transporter activity
IC785_RS08755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC785_RS08760	COG0745	RESPONSE REGULATOR receiver
IC785_RS08770	COG2146	nitrite reductase [NAD(P)H] activity
IC785_RS08770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC785_RS08775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC785_RS08790	COG0243	molybdopterin cofactor binding
IC785_RS08795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC785_RS08810	COG0315	cyclic pyranopterin monophosphate synthase activity
IC785_RS08810	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC785_RS08815	COG0303	'Molybdopterin
IC785_RS08830	COG0697	spore germination
IC785_RS08850	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC785_RS08855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC785_RS08910	COG2204	response regulator
IC785_RS08915	COG3852	Histidine kinase
IC785_RS08940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC785_RS08945	COG0575	Belongs to the CDS family
IC785_RS08960	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC785_RS08980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC785_RS08995	COG2137	regulation of response to DNA damage stimulus
IC785_RS09005	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC785_RS09010	COG1011	Hydrolase
IC785_RS09025	COG1522	sequence-specific DNA binding
IC785_RS09035	COG1113	amino acid transport
IC785_RS09050	COG0659	secondary active sulfate transmembrane transporter activity
IC785_RS09070	COG4372	Transposase
IC785_RS09105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC785_RS09105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC785_RS09105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC785_RS09110	COG1105	Belongs to the carbohydrate kinase PfkB family
IC785_RS09115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC785_RS09115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC785_RS09145	COG0024	Methionine aminopeptidase
IC785_RS09150	COG0583	DNA-binding transcription factor activity
IC785_RS09160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC785_RS09165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC785_RS09170	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC785_RS09195	COG0552	protein localization to endoplasmic reticulum
IC785_RS09220	COG4890	Cyd operon protein YbgT
IC785_RS09225	COG1294	oxidase, subunit
IC785_RS09240	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC785_RS09250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC785_RS09255	COG4774	siderophore transport
IC785_RS09270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC785_RS09275	COG0569	domain protein
IC785_RS09280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC785_RS09310	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC785_RS09315	COG0542	response to heat
IC785_RS09340	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC785_RS09340	COG1902	pentaerythritol trinitrate reductase activity
IC785_RS09380	COG0148	phosphopyruvate hydratase activity
IC785_RS09385	COG2323	membrane
IC785_RS09395	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC785_RS09405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC785_RS09410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC785_RS09415	COG0183	Belongs to the thiolase family
IC785_RS09420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC785_RS09425	COG0596	Alpha beta hydrolase
IC785_RS09430	COG2271	Major facilitator Superfamily
IC785_RS09435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC785_RS09440	COG3485	protocatechuate 3,4-dioxygenase
IC785_RS09445	COG3485	protocatechuate 3,4-dioxygenase
IC785_RS09450	COG0710	3-dehydroquinate dehydratase activity
IC785_RS09455	COG3420	alginic acid biosynthetic process
IC785_RS09460	COG3659	wide pore channel activity
IC785_RS09465	COG4993	Dehydrogenase
IC785_RS09475	COG2391	methyltransferase activity
IC785_RS09490	COG1414	Transcriptional regulator
IC785_RS09495	COG0583	DNA-binding transcription factor activity
IC785_RS09500	COG1960	acyl-CoA dehydrogenase activity
IC785_RS09525	COG2814	Major facilitator Superfamily
IC785_RS09535	COG0154	amidase activity
IC785_RS09555	COG4638	Rieske (2fe-2S)
IC785_RS09565	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS09575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC785_RS09585	COG3733	amine oxidase
IC785_RS09600	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS09605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC785_RS09610	COG0183	Belongs to the thiolase family
IC785_RS09615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC785_RS09620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC785_RS09630	COG4829	muconolactone delta-isomerase
IC785_RS09635	COG4948	Mandelate Racemase Muconate Lactonizing
IC785_RS09640	COG0583	DNA-binding transcription factor activity
IC785_RS09670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC785_RS09695	COG1309	transcriptional regulator
IC785_RS09780	COG2188	Transcriptional regulator
IC785_RS09795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC785_RS09810	COG2271	Major facilitator Superfamily
IC785_RS09820	COG1566	PFAM secretion protein HlyD family protein
IC785_RS09850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC785_RS09855	COG1120	ATPase activity
IC785_RS09875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC785_RS09995	COG2175	clavaminate synthase activity
IC785_RS10000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC785_RS10015	COG0667	Aldo Keto reductase
IC785_RS10020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC785_RS10035	COG2175	clavaminate synthase activity
IC785_RS10065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC785_RS10070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC785_RS10075	COG4771	TonB-dependent receptor
IC785_RS10105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC785_RS10110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC785_RS10115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC785_RS10120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC785_RS10135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC785_RS10140	COG0805	protein transport
IC785_RS10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC785_RS10185	COG1132	(ABC) transporter
IC785_RS10205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC785_RS10210	COG0601	transmembrane transport
IC785_RS10240	COG3539	Fimbrial protein
IC785_RS10265	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC785_RS10275	COG0753	catalase activity
IC785_RS10285	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC785_RS10290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC785_RS10300	COG2205	protein histidine kinase activity
IC785_RS10305	COG0745	RESPONSE REGULATOR receiver
IC785_RS10310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS10315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC785_RS10375	COG4771	TonB-dependent receptor
IC785_RS10385	COG3433	isochorismatase activity
IC785_RS10385	COG1535	isochorismatase
IC785_RS10390	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC785_RS10395	COG1169	isochorismate synthase
IC785_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS10410	COG3251	PFAM MbtH domain protein
IC785_RS10415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC785_RS10440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC785_RS10445	COG4149	molybdate abc transporter
IC785_RS10450	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC785_RS10460	COG4638	Rieske (2fe-2S)
IC785_RS10465	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC785_RS10470	COG0543	2 iron, 2 sulfur cluster binding
IC785_RS10470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC785_RS10485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC785_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS10515	COG2207	Transcriptional regulator
IC785_RS10520	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS10525	COG2610	gluconate transmembrane transporter activity
IC785_RS10530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC785_RS10560	COG2814	Major facilitator Superfamily
IC785_RS10585	COG0583	DNA-binding transcription factor activity
IC785_RS10600	COG2031	fatty acid transporter
IC785_RS10605	COG0183	Belongs to the thiolase family
IC785_RS10610	COG0583	DNA-binding transcription factor activity
IC785_RS10615	COG0583	DNA-binding transcription factor activity
IC785_RS10630	COG1027	Aspartate ammonia-lyase
IC785_RS10640	COG0477	Major facilitator Superfamily
IC785_RS10650	COG3708	Transcriptional regulator
IC785_RS10650	COG2207	Transcriptional regulator
IC785_RS10665	COG0730	response to heat
IC785_RS10675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC785_RS10675	COG3453	Protein conserved in bacteria
IC785_RS10685	COG3781	membrane
IC785_RS10690	COG1063	alcohol dehydrogenase
IC785_RS10700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC785_RS10705	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC785_RS10710	COG0022	dehydrogenase e1 component
IC785_RS10715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC785_RS10720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC785_RS10735	COG3706	GGDEF domain
IC785_RS10750	COG0133	tryptophan synthase activity
IC785_RS10760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC785_RS10795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC785_RS10820	COG2226	methyltransferase
IC785_RS10875	COG0842	Transport permease protein
IC785_RS10880	COG0842	Transport permease protein
IC785_RS10885	COG1131	(ABC) transporter
IC785_RS10900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC785_RS10905	COG4773	Receptor
IC785_RS10925	COG0730	response to heat
IC785_RS10930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC785_RS10945	COG0406	alpha-ribazole phosphatase activity
IC785_RS10950	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC785_RS10965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC785_RS10970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC785_RS10985	COG1960	acyl-CoA dehydrogenase activity
IC785_RS10990	COG1960	acyl-CoA dehydrogenase activity
IC785_RS10995	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC785_RS11000	COG2207	Transcriptional regulator
IC785_RS11005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC785_RS11010	COG0776	regulation of translation
IC785_RS11035	COG0822	iron-sulfur transferase activity
IC785_RS11040	COG0316	Belongs to the HesB IscA family
IC785_RS11090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC785_RS11095	COG0702	epimerase
IC785_RS11125	COG4172	Belongs to the ABC transporter superfamily
IC785_RS11130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC785_RS11135	COG0601	transmembrane transport
IC785_RS11160	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC785_RS11185	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC785_RS11305	COG4695	Portal protein
IC785_RS11390	COG0305	Participates in initiation and elongation during chromosome replication
IC785_RS11405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC785_RS11450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC785_RS11465	COG2431	L-lysine efflux transmembrane transporter activity
IC785_RS11480	COG0776	regulation of translation
IC785_RS11545	COG0084	hydrolase, TatD family'
IC785_RS11570	COG1132	(ABC) transporter
IC785_RS11580	COG0811	peptide transport
IC785_RS11585	COG1475	DNA binding
IC785_RS11590	COG1192	Involved in chromosome partitioning
IC785_RS11600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC785_RS11615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC785_RS11640	COG0424	maF-like protein
IC785_RS11645	COG2850	peptidyl-arginine hydroxylation
IC785_RS11665	COG3619	membrane
IC785_RS11670	COG3122	Protein conserved in bacteria
IC785_RS11675	COG1132	(ABC) transporter
IC785_RS11695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC785_RS11700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC785_RS11710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC785_RS11710	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC785_RS11710	COG0506	proline dehydrogenase activity
IC785_RS11715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC785_RS11730	COG3698	Phosphodiester glycosidase
IC785_RS11740	COG2353	YceI-like domain
IC785_RS11755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC785_RS11795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC785_RS11795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC785_RS11820	COG3539	Fimbrial protein
IC785_RS11825	COG3121	Chaperone
IC785_RS11845	COG0697	spore germination
IC785_RS11855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC785_RS11865	COG0583	DNA-binding transcription factor activity
IC785_RS11870	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS11890	COG2197	response regulator
IC785_RS11915	COG1522	sequence-specific DNA binding
IC785_RS11925	COG1126	abc transporter atp-binding protein
IC785_RS11930	COG0765	amino acid transport
IC785_RS11935	COG0765	amino acid transport
IC785_RS11965	COG1464	Belongs to the NlpA lipoprotein family
IC785_RS11975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC785_RS11980	COG2011	ABC-type metal ion transport system permease component
IC785_RS11985	COG0012	GTP binding
IC785_RS12010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC785_RS12045	COG2207	Transcriptional regulator
IC785_RS12045	COG1917	Cupin 2, conserved barrel domain protein
IC785_RS12050	COG0386	Belongs to the glutathione peroxidase family
IC785_RS12060	COG0436	Aminotransferase
IC785_RS12065	COG1301	dicarboxylic acid transport
IC785_RS12100	COG3634	alkyl hydroperoxide reductase activity
IC785_RS12115	COG0583	DNA-binding transcription factor activity
IC785_RS12120	COG0431	NADPH-dependent FMN reductase
IC785_RS12125	COG0798	PFAM Bile acid sodium symporter
IC785_RS12130	COG0640	Transcriptional regulator
IC785_RS12145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC785_RS12165	COG1953	Uracil, thiamine, allantoin
IC785_RS12175	COG2175	clavaminate synthase activity
IC785_RS12180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC785_RS12185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC785_RS12190	COG4521	taurine ABC transporter
IC785_RS12200	COG0477	Major facilitator Superfamily
IC785_RS12220	COG1271	oxidase subunit
IC785_RS12225	COG1294	oxidase, subunit
IC785_RS12235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC785_RS12255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC785_RS12275	COG3052	prosthetic group binding
IC785_RS12280	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC785_RS12305	COG1346	cytolysis
IC785_RS12315	COG0583	DNA-binding transcription factor activity
IC785_RS12320	COG0625	glutathione transferase activity
IC785_RS12325	COG0625	glutathione transferase activity
IC785_RS12330	COG0583	DNA-binding transcription factor activity
IC785_RS12345	COG1045	serine acetyltransferase
IC785_RS12350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC785_RS12355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC785_RS12360	COG1280	lysine exporter protein (LysE YggA)
IC785_RS12370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC785_RS12375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC785_RS12385	COG0765	amino acid transport
IC785_RS12390	COG0765	amino acid transport
IC785_RS12430	COG0784	Response regulator, receiver
IC785_RS12430	COG2205	protein histidine kinase activity
IC785_RS12450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC785_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS12515	COG0583	DNA-binding transcription factor activity
IC785_RS12535	COG0318	PFAM AMP-dependent synthetase and ligase
IC785_RS12540	COG1309	transcriptional regulator
IC785_RS12545	COG1960	acyl-CoA dehydrogenase activity
IC785_RS12550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC785_RS12555	COG1024	Enoyl-CoA hydratase
IC785_RS12560	COG4770	biotin carboxylase activity
IC785_RS12570	COG0583	DNA-binding transcription factor activity
IC785_RS12585	COG1960	acyl-CoA dehydrogenase activity
IC785_RS12595	COG2814	Major facilitator Superfamily
IC785_RS12605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC785_RS12610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC785_RS12615	COG2814	Major facilitator Superfamily
IC785_RS12620	COG1960	acyl-CoA dehydrogenase activity
IC785_RS12625	COG1024	Enoyl-CoA hydratase
IC785_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS12635	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC785_RS12640	COG0183	Belongs to the thiolase family
IC785_RS12650	COG2814	Major facilitator Superfamily
IC785_RS12665	COG1024	Enoyl-CoA hydratase
IC785_RS12675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC785_RS12680	COG1960	acyl-CoA dehydrogenase activity
IC785_RS12685	COG2814	Major facilitator Superfamily
IC785_RS12690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC785_RS12695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC785_RS12710	COG3842	ATPase activity
IC785_RS12715	COG1840	ABC-type Fe3 transport system, periplasmic component
IC785_RS12730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC785_RS12735	COG1414	Transcriptional regulator
IC785_RS12745	COG0583	DNA-binding transcription factor activity
IC785_RS12760	COG3038	cytochrome b561
IC785_RS12765	COG0753	catalase activity
IC785_RS12770	COG0531	amino acid
IC785_RS12775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC785_RS12790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC785_RS12795	COG1309	transcriptional regulator
IC785_RS12835	COG3179	chitinase
IC785_RS12855	COG0406	alpha-ribazole phosphatase activity
IC785_RS12865	COG2050	protein possibly involved in aromatic compounds catabolism
IC785_RS12875	COG3327	negative regulation of DNA-templated transcription, initiation
IC785_RS12880	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC785_RS12890	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC785_RS12895	COG1024	Enoyl-CoA hydratase
IC785_RS12900	COG1024	Enoyl-CoA hydratase
IC785_RS12905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC785_RS12910	COG2151	metal-sulfur cluster biosynthetic enzyme
IC785_RS12915	COG3396	Phenylacetate-CoA oxygenase
IC785_RS12920	COG3460	Phenylacetate-CoA oxygenase
IC785_RS12925	COG3396	Phenylacetate-CoA oxygenase
IC785_RS12930	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS12930	COG2030	dehydratase
IC785_RS12935	COG1760	l-serine dehydratase
IC785_RS12945	COG0789	Transcriptional regulator
IC785_RS12955	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC785_RS12960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC785_RS12975	COG2807	transmembrane transport
IC785_RS12980	COG0590	tRNA wobble adenosine to inosine editing
IC785_RS13085	COG0477	Major facilitator Superfamily
IC785_RS13100	COG1116	anion transmembrane transporter activity
IC785_RS13105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC785_RS13115	COG0864	Transcriptional regulator
IC785_RS13130	COG1733	regulation of RNA biosynthetic process
IC785_RS13135	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC785_RS13140	COG0439	Biotin carboxylase
IC785_RS13155	COG1063	alcohol dehydrogenase
IC785_RS13205	COG0038	chloride channel
IC785_RS13210	COG4770	biotin carboxylase activity
IC785_RS13230	COG1914	H( )-stimulated, divalent metal cation uptake system
IC785_RS13235	COG0583	DNA-binding transcription factor activity
IC785_RS13245	COG1595	DNA-templated transcription, initiation
IC785_RS13255	COG3220	belongs to the UPF0276 family
IC785_RS13270	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS13285	COG2076	Multidrug Resistance protein
IC785_RS13300	COG3713	MltA-interacting MipA family protein
IC785_RS13305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC785_RS13350	COG3209	COG3209 Rhs family protein
IC785_RS13430	COG1309	transcriptional regulator
IC785_RS13435	COG1278	Cold shock
IC785_RS13450	COG1522	sequence-specific DNA binding
IC785_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS13470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC785_RS13475	COG4774	siderophore transport
IC785_RS13495	COG2814	Major facilitator Superfamily
IC785_RS13510	COG0402	S-adenosylhomocysteine deaminase activity
IC785_RS13515	COG0583	DNA-binding transcription factor activity
IC785_RS13525	COG1271	oxidase subunit
IC785_RS13530	COG1294	oxidase, subunit
IC785_RS13540	COG1469	GTP cyclohydrolase I activity
IC785_RS13605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC785_RS13615	COG4122	O-methyltransferase activity
IC785_RS13645	COG1538	Outer membrane efflux protein
IC785_RS13650	COG1137	ATPase activity
IC785_RS13655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC785_RS13665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC785_RS13670	COG0517	IMP dehydrogenase activity
IC785_RS13670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC785_RS13700	COG2814	Major facilitator Superfamily
IC785_RS13805	COG4397	Mu-like prophage major head subunit gpT
IC785_RS13825	COG2369	cell adhesion
IC785_RS13830	COG4383	Mu-like prophage protein gp29
IC785_RS13840	COG4373	Mu-like prophage FluMu protein gp28
IC785_RS13875	COG0681	Belongs to the peptidase S26 family
IC785_RS13990	COG1278	Cold shock
IC785_RS13995	COG1280	lysine exporter protein (LysE YggA)
IC785_RS14030	COG1570	exodeoxyribonuclease VII activity
IC785_RS14115	COG2871	sodium ion transport
IC785_RS14125	COG0583	DNA-binding transcription factor activity
IC785_RS14135	COG4638	Rieske (2fe-2S)
IC785_RS14140	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC785_RS14145	COG0633	Ferredoxin
IC785_RS14145	COG0543	2 iron, 2 sulfur cluster binding
IC785_RS14150	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS14155	COG3135	benzoate transporter
IC785_RS14160	COG2814	Major facilitator Superfamily
IC785_RS14175	COG1643	Atp-dependent helicase
IC785_RS14190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC785_RS14210	COG3634	alkyl hydroperoxide reductase activity
IC785_RS14230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC785_RS14235	COG0625	glutathione transferase activity
IC785_RS14280	COG0542	response to heat
IC785_RS14295	COG1765	OsmC-like protein
IC785_RS14305	COG0667	Aldo Keto reductase
IC785_RS14320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC785_RS14335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC785_RS14345	COG0527	aspartate kinase activity
IC785_RS14355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC785_RS14365	COG3038	cytochrome b561
IC785_RS14370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC785_RS14375	COG2252	PERMEase
IC785_RS14385	COG2072	flavoprotein involved in K transport
IC785_RS14400	COG1741	Belongs to the pirin family
IC785_RS14405	COG1309	transcriptional regulator
IC785_RS14420	COG2072	flavoprotein involved in K transport
IC785_RS14425	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC785_RS14430	COG0583	DNA-binding transcription factor activity
IC785_RS14445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC785_RS14475	COG1944	ATP diphosphatase activity
IC785_RS14495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC785_RS14510	COG2814	Major facilitator Superfamily
IC785_RS14515	COG1024	Enoyl-CoA hydratase
IC785_RS14520	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS14530	COG1960	acyl-CoA dehydrogenase activity
IC785_RS14550	COG0697	spore germination
IC785_RS14570	COG1113	amino acid transport
IC785_RS14575	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS14595	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS14615	COG0531	amino acid
IC785_RS14625	COG1113	amino acid transport
IC785_RS14675	COG1846	Transcriptional regulator
IC785_RS14725	COG4269	membrane
IC785_RS14745	COG0583	DNA-binding transcription factor activity
IC785_RS14755	COG0251	oxidation-reduction process
IC785_RS14770	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC785_RS14770	COG1902	pentaerythritol trinitrate reductase activity
IC785_RS14780	COG4251	negative regulation of phosphorylation
IC785_RS14780	COG5001	Diguanylate cyclase
IC785_RS14780	COG3706	GGDEF domain
IC785_RS14780	COG2203	Gaf domain
IC785_RS14790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC785_RS14815	COG4172	Belongs to the ABC transporter superfamily
IC785_RS14820	COG4239	(ABC) transporter, permease
IC785_RS14825	COG4174	ABC transporter (Permease)
IC785_RS14835	COG1388	LysM domain
IC785_RS14835	COG0741	lytic transglycosylase activity
IC785_RS14880	COG0583	DNA-binding transcription factor activity
IC785_RS14905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC785_RS14910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC785_RS14915	COG0006	proline dipeptidase activity
IC785_RS15245	COG1674	ftsk spoiiie
IC785_RS15275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC785_RS15315	COG3384	dioxygenase
IC785_RS15325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC785_RS15330	COG2878	Part of a membrane complex involved in electron transport
IC785_RS15335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC785_RS15360	COG0768	penicillin binding
IC785_RS15365	COG0742	ribosomal rna small subunit methyltransferase
IC785_RS15385	COG0830	nickel cation binding
IC785_RS15395	COG0804	urea catabolic process
IC785_RS15435	COG1253	flavin adenine dinucleotide binding
IC785_RS15440	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS15445	COG2851	Citrate transporter
IC785_RS15495	COG1773	rubredoxin
IC785_RS15500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC785_RS15510	COG0583	DNA-binding transcription factor activity
IC785_RS15535	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC785_RS15540	COG4181	ATPase activity
IC785_RS15585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC785_RS15605	COG0306	phosphate transporter
IC785_RS15640	COG2223	nitrite transmembrane transporter activity
IC785_RS15645	COG2207	Transcriptional regulator
IC785_RS15650	COG2066	Belongs to the glutaminase family
IC785_RS15655	COG0242	peptide deformylase activity
IC785_RS15670	COG0028	Belongs to the TPP enzyme family
IC785_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS15690	COG2267	carboxylic ester hydrolase activity
IC785_RS15700	COG2271	Major facilitator Superfamily
IC785_RS15735	COG1414	Transcriptional regulator
IC785_RS15765	COG1024	Enoyl-CoA hydratase
IC785_RS15775	COG1215	transferase activity, transferring glycosyl groups
IC785_RS15780	COG1649	PFAM Uncharacterised BCR, COG1649
IC785_RS15780	COG0726	polysaccharide deacetylase
IC785_RS15790	COG4681	YaeQ
IC785_RS15800	COG0523	cobalamin synthesis protein
IC785_RS15810	COG1607	acyl-coa hydrolase
IC785_RS15820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC785_RS15825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC785_RS15830	COG1309	transcriptional regulator
IC785_RS15855	COG2040	homocysteine
IC785_RS15860	COG0531	amino acid
IC785_RS15880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC785_RS15885	COG0477	Major facilitator Superfamily
IC785_RS15915	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS15925	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC785_RS15930	COG3586	endonuclease activity
IC785_RS15990	COG0405	Gamma-glutamyltransferase
IC785_RS15995	COG2814	Major facilitator Superfamily
IC785_RS16005	COG2050	protein possibly involved in aromatic compounds catabolism
IC785_RS16020	COG1090	epimerase
IC785_RS16040	COG0420	3'-5' exonuclease activity
IC785_RS16060	COG4372	Transposase
IC785_RS16065	COG1968	undecaprenyl-diphosphatase activity
IC785_RS16085	COG0735	belongs to the Fur family
IC785_RS16090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC785_RS16095	COG2914	Belongs to the UPF0125 (RnfH) family
IC785_RS16110	COG0121	glutamine amidotransferase
IC785_RS16125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC785_RS16135	COG0210	DNA helicase
IC785_RS16140	COG2885	chlorophyll binding
IC785_RS16145	COG0204	Acyl-transferase
IC785_RS16160	COG2894	cell division
IC785_RS16175	COG1280	lysine exporter protein (LysE YggA)
IC785_RS16180	COG1674	ftsk spoiiie
IC785_RS16185	COG0492	ferredoxin-NADP+ reductase activity
IC785_RS16190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC785_RS16200	COG0456	acetyltransferase
IC785_RS16220	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC785_RS16230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC785_RS16245	COG1981	membrane
IC785_RS16255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC785_RS16255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC785_RS16275	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS16280	COG4638	Rieske (2fe-2S)
IC785_RS16285	COG0657	acetylesterase activity
IC785_RS16295	COG0473	3-isopropylmalate dehydrogenase activity
IC785_RS16300	COG0583	DNA-binding transcription factor activity
IC785_RS16320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC785_RS16345	COG0564	pseudouridine synthase activity
IC785_RS16355	COG0358	DNA primase activity
IC785_RS16370	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC785_RS16400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC785_RS16430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC785_RS16440	COG0352	thiamine-phosphate diphosphorylase activity
IC785_RS16440	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC785_RS16440	COG0351	phosphomethylpyrimidine kinase
IC785_RS16445	COG1652	LysM domain
IC785_RS16470	COG1399	metal-binding, possibly nucleic acid-binding protein
IC785_RS16475	COG3101	peptidyl-lysine hydroxylation
IC785_RS16480	COG0009	L-threonylcarbamoyladenylate synthase
IC785_RS16485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC785_RS16490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC785_RS16505	COG4106	trans-aconitate 2-methyltransferase activity
IC785_RS16520	COG2226	methyltransferase
IC785_RS16520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC785_RS16520	COG0596	Alpha beta hydrolase
IC785_RS16525	COG1877	trehalose-phosphatase activity
IC785_RS16530	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC785_RS16535	COG2223	nitrite transmembrane transporter activity
IC785_RS16555	COG1196	nuclear chromosome segregation
IC785_RS16565	COG0730	response to heat
IC785_RS16580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC785_RS16590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC785_RS16635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC785_RS16640	COG0489	protein tyrosine kinase activity
IC785_RS16650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC785_RS16650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC785_RS16685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC785_RS16690	COG2081	HI0933 family
IC785_RS16700	COG0668	transmembrane transport
IC785_RS16720	COG0583	DNA-binding transcription factor activity
IC785_RS16745	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC785_RS16750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC785_RS16765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC785_RS16780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC785_RS16805	COG3706	GGDEF domain
IC785_RS16820	COG0745	RESPONSE REGULATOR receiver
IC785_RS16840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC785_RS16870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC785_RS16875	COG0583	DNA-binding transcription factor activity
IC785_RS16915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC785_RS16930	COG0583	DNA-binding transcription factor activity
IC785_RS16940	COG0583	DNA-binding transcription factor activity
IC785_RS16955	COG0583	DNA-binding transcription factor activity
IC785_RS16960	COG1053	succinate dehydrogenase
IC785_RS16975	COG1309	transcriptional regulator
IC785_RS16985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC785_RS16990	COG2814	Major facilitator Superfamily
IC785_RS16995	COG1960	acyl-CoA dehydrogenase activity
IC785_RS17000	COG0583	DNA-binding transcription factor activity
IC785_RS17005	COG1063	alcohol dehydrogenase
IC785_RS17035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC785_RS17040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC785_RS17045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC785_RS17065	COG2132	Multicopper oxidase
IC785_RS17075	COG0561	phosphatase activity
IC785_RS17080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC785_RS17090	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC785_RS17105	COG1214	PFAM Peptidase M22, glycoprotease
IC785_RS17155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC785_RS17165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC785_RS17170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC785_RS17175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC785_RS17235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC785_RS17245	COG1846	Transcriptional regulator
IC785_RS17250	COG1764	response to oxidative stress
IC785_RS17290	COG0037	tRNA processing
IC785_RS17300	COG0248	Ppx GppA phosphatase
IC785_RS17330	COG0072	phenylalanine-tRNA ligase activity
IC785_RS17360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC785_RS17370	COG1238	metal cluster binding
IC785_RS17375	COG0625	glutathione transferase activity
IC785_RS17390	COG0318	PFAM AMP-dependent synthetase and ligase
IC785_RS17395	COG3028	Belongs to the UPF0307 family
IC785_RS17420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC785_RS17425	COG0617	tRNA 3'-terminal CCA addition
IC785_RS17430	COG1555	photosystem II stabilization
IC785_RS17435	COG3956	TIGRFAM MazG family protein
IC785_RS17445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC785_RS17465	COG5002	protein histidine kinase activity
IC785_RS17465	COG2205	protein histidine kinase activity
IC785_RS17465	COG0784	Response regulator, receiver
IC785_RS17470	COG1024	Enoyl-CoA hydratase
IC785_RS17475	COG2084	Dehydrogenase
IC785_RS17480	COG3622	Belongs to the hyi family
IC785_RS17515	COG0697	spore germination
IC785_RS17525	COG2814	Major facilitator Superfamily
IC785_RS17550	COG1230	cation diffusion facilitator family transporter
IC785_RS17565	COG2814	Major facilitator Superfamily
IC785_RS17670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC785_RS17680	COG0583	DNA-binding transcription factor activity
IC785_RS17690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC785_RS17700	COG0084	hydrolase, TatD family'
IC785_RS17715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC785_RS17750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC785_RS17755	COG0440	acetolactate synthase activity
IC785_RS17760	COG0028	Belongs to the TPP enzyme family
IC785_RS17785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC785_RS17790	COG1136	(ABC) transporter
IC785_RS17790	COG0577	efflux transmembrane transporter activity
IC785_RS17795	COG1538	Outer membrane efflux protein
IC785_RS17810	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC785_RS17815	COG1162	GTPase activity
IC785_RS17825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC785_RS17865	COG1426	Protein conserved in bacteria
IC785_RS17900	COG0793	Belongs to the peptidase S41A family
IC785_RS17925	COG1012	belongs to the aldehyde dehydrogenase family
IC785_RS17930	COG3265	gluconokinase activity
IC785_RS17940	COG0800	Aldolase
IC785_RS17950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC785_RS17955	COG0280	phosphate acetyltransferase
IC785_RS17955	COG0857	belongs to the CobB CobQ family
IC785_RS17960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC785_RS17960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC785_RS17980	COG0740	serine-type endopeptidase activity
IC785_RS17990	COG4774	siderophore transport
IC785_RS18000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC785_RS18010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC785_RS18010	COG2813	Specifically methylates the guanine in position
IC785_RS18105	COG0788	formyltetrahydrofolate deformylase activity
IC785_RS18130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC785_RS18130	COG4651	solute:proton antiporter activity
IC785_RS18150	COG0724	RNA recognition motif
IC785_RS18155	COG0210	DNA helicase
IC785_RS18180	COG1733	regulation of RNA biosynthetic process
IC785_RS18190	COG2900	Belongs to the SlyX family
IC785_RS18195	COG0488	(ABC) transporter
IC785_RS18205	COG1280	lysine exporter protein (LysE YggA)
IC785_RS18210	COG1560	Kdo2-lipid A biosynthetic process
IC785_RS18220	COG1301	dicarboxylic acid transport
IC785_RS18275	COG0473	3-isopropylmalate dehydrogenase activity
IC785_RS18345	COG0583	DNA-binding transcription factor activity
IC785_RS18355	COG0625	glutathione transferase activity
IC785_RS18360	COG2378	regulation of single-species biofilm formation
IC785_RS18375	COG1530	ribonuclease E activity
IC785_RS18380	COG0318	PFAM AMP-dependent synthetase and ligase
IC785_RS18395	COG0583	DNA-binding transcription factor activity
IC785_RS18400	COG4221	oxidoreductase activity
IC785_RS18405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC785_RS18415	COG0534	Mate efflux family protein
IC785_RS18430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC785_RS18460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC785_RS18460	COG0493	'glutamate synthase
IC785_RS18470	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC785_RS18475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC785_RS18490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC785_RS18500	COG0644	oxidoreductase
IC785_RS18500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC785_RS18515	COG4535	Mg2 and Co2 transporter CorC
IC785_RS18525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC785_RS18550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC785_RS18555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC785_RS18555	COG0475	glutathione-regulated potassium exporter activity
IC785_RS18560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC785_RS18570	COG0484	heat shock protein binding
IC785_RS18575	COG0789	Transcriptional regulator
IC785_RS18580	COG0598	Magnesium transport protein CorA
IC785_RS18585	COG1185	polyribonucleotide nucleotidyltransferase activity
IC785_RS18595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC785_RS18600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC785_RS18605	COG1074	ATP-dependent DNA helicase activity
IC785_RS18610	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC785_RS18635	COG2226	methyltransferase
IC785_RS18650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC785_RS18665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC785_RS18680	COG2111	Na H antiporter
IC785_RS18680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC785_RS18685	COG1006	Multisubunit Na H antiporter MnhC subunit
IC785_RS18690	COG0651	ATP synthesis coupled electron transport
IC785_RS18695	COG1863	multisubunit Na H antiporter MnhE subunit
IC785_RS18700	COG2212	antiporter activity
IC785_RS18705	COG1320	monovalent cation:proton antiporter activity
IC785_RS18710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC785_RS18720	COG0195	Participates in both transcription termination and antitermination
IC785_RS18770	COG0237	dephospho-CoA kinase activity
IC785_RS18780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC785_RS18790	COG0497	DNA recombination
IC785_RS18800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC785_RS18815	COG1289	transmembrane transporter activity
IC785_RS18830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC785_RS18895	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC785_RS18910	COG0326	Molecular chaperone. Has ATPase activity
IC785_RS18925	COG2056	Na+-H+ antiporter family
IC785_RS18930	COG0596	Alpha beta hydrolase
IC785_RS19025	COG0546	phosphoglycolate phosphatase activity
IC785_RS19030	COG1716	ATPase activity
IC785_RS19075	COG0181	hydroxymethylbilane synthase activity
IC785_RS19085	COG3275	phosphorelay sensor kinase activity
IC785_RS19105	COG1538	Outer membrane efflux protein
IC785_RS19115	COG0697	spore germination
IC785_RS19135	COG0494	nUDIX hydrolase
IC785_RS19145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC785_RS19150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC785_RS19155	COG0772	Belongs to the SEDS family
IC785_RS19180	COG4974	Belongs to the 'phage' integrase family
IC785_RS19185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC785_RS19195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC785_RS19205	COG2197	response regulator
IC785_RS19220	COG0793	Belongs to the peptidase S41A family
IC785_RS19225	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC785_RS19230	COG0795	lipopolysaccharide-transporting ATPase activity
IC785_RS19235	COG0795	lipopolysaccharide-transporting ATPase activity
IC785_RS19270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC785_RS19270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC785_RS19280	COG0004	ammonium transporteR
IC785_RS19285	COG0347	Belongs to the P(II) protein family
IC785_RS19295	COG0606	chelatase, subunit chli
IC785_RS19300	COG0431	NADPH-dependent FMN reductase
IC785_RS19305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC785_RS19310	COG0235	Class ii aldolase
IC785_RS19315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC785_RS19330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC785_RS19345	COG0318	PFAM AMP-dependent synthetase and ligase
IC785_RS19355	COG0477	Major facilitator Superfamily
IC785_RS19360	COG2860	membrane
IC785_RS19370	COG1253	flavin adenine dinucleotide binding
IC785_RS19380	COG2814	Major facilitator Superfamily
IC785_RS19390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC785_RS19425	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC785_RS19440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC785_RS19475	COG1309	transcriptional regulator
IC785_RS19510	COG0758	DNA mediated transformation
IC785_RS19520	COG0697	spore germination
IC785_RS19525	COG1309	transcriptional regulator
IC785_RS19540	COG0386	Belongs to the glutathione peroxidase family
IC785_RS19550	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC785_RS19555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC785_RS19605	COG1121	(ABC) transporter
IC785_RS19610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC785_RS19615	COG1280	lysine exporter protein (LysE YggA)
IC785_RS19625	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS19635	COG0281	malic enzyme
IC785_RS19670	COG0735	belongs to the Fur family
IC785_RS19680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC785_RS19685	COG0519	Catalyzes the synthesis of GMP from XMP
IC785_RS19685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC785_RS19690	COG4399	Belongs to the UPF0754 family
IC785_RS19690	COG4399	Belongs to the UPF0754 family
IC785_RS19695	COG2259	Doxx family
IC785_RS19700	COG0586	Pfam SNARE associated Golgi protein
IC785_RS19715	COG1192	Involved in chromosome partitioning
IC785_RS19725	COG0271	Belongs to the BolA IbaG family
IC785_RS19765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC785_RS19765	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC785_RS19765	COG3321	synthase
IC785_RS19765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC785_RS19770	COG1960	acyl-CoA dehydrogenase activity
IC785_RS19780	COG2197	response regulator
IC785_RS19790	COG3916	Acyl-homoserine-lactone synthase
IC785_RS19795	COG0477	Major facilitator Superfamily
IC785_RS19800	COG1024	Enoyl-CoA hydratase
IC785_RS19805	COG1024	Enoyl-CoA hydratase
IC785_RS19810	COG1960	acyl-CoA dehydrogenase activity
IC785_RS19815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC785_RS19835	COG1113	amino acid transport
IC785_RS19840	COG1113	amino acid transport
IC785_RS19845	COG0251	oxidation-reduction process
IC785_RS19885	COG0564	pseudouridine synthase activity
IC785_RS19955	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC785_RS19970	COG1802	Transcriptional regulator
IC785_RS19980	COG1448	Aminotransferase
IC785_RS19985	COG0277	FAD linked oxidase domain protein
IC785_RS19995	COG2186	Transcriptional regulator
IC785_RS20005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC785_RS20025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC785_RS20030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC785_RS20050	COG0463	Glycosyl transferase, family 2
IC785_RS20050	COG1216	Glycosyl transferase, family 2
IC785_RS20085	COG1086	Polysaccharide biosynthesis protein
IC785_RS20095	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC785_RS20100	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC785_RS20110	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC785_RS20115	COG1596	polysaccharide export
IC785_RS20140	COG0728	peptidoglycan biosynthetic process
IC785_RS20145	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC785_RS20200	COG0546	phosphoglycolate phosphatase activity
IC785_RS20205	COG1028	Short-chain dehydrogenase reductase Sdr
IC785_RS20220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC785_RS20220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC785_RS20225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC785_RS20230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC785_RS20235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC785_RS20240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC785_RS20245	COG1116	anion transmembrane transporter activity
IC785_RS20250	COG1309	transcriptional regulator
IC785_RS20255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC785_RS20265	COG0196	riboflavin kinase activity
IC785_RS20270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC785_RS20280	COG1047	Peptidyl-prolyl cis-trans
IC785_RS20320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC785_RS20325	COG0657	acetylesterase activity
IC785_RS20365	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS20385	COG2951	lytic endotransglycosylase activity
IC785_RS20390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC785_RS20405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC785_RS20415	COG0671	phosphoesterase, PA-phosphatase related
IC785_RS20420	COG0861	Integral membrane protein TerC family
IC785_RS20430	COG0754	glutathionylspermidine amidase activity
IC785_RS20440	COG0402	S-adenosylhomocysteine deaminase activity
IC785_RS20455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC785_RS20655	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS20675	COG0501	Belongs to the peptidase M48B family
IC785_RS20715	COG4372	Transposase
IC785_RS20740	COG0589	response to stress
IC785_RS20745	COG0659	secondary active sulfate transmembrane transporter activity
IC785_RS20775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC785_RS20880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC785_RS20955	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS20965	COG2826	transposase and inactivated derivatives, IS30 family
IC785_RS21065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC785_RS21115	COG1192	Involved in chromosome partitioning
IC785_RS21130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC785_RS21205	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC785_RS21240	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC785_RS21245	COG0659	secondary active sulfate transmembrane transporter activity
IC785_RS21260	COG3328	transposase activity
IC785_RS21265	COG0583	DNA-binding transcription factor activity
IC785_RS21270	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC785_RS21275	COG0604	alcohol dehydrogenase
IC785_RS21275	COG3321	synthase
IC785_RS21285	COG0697	spore germination
IC785_RS21290	COG0477	Major facilitator Superfamily
IC785_RS21320	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC785_RS21335	COG1979	alcohol dehydrogenase
IC785_RS21345	COG1902	pentaerythritol trinitrate reductase activity
IC785_RS21355	COG1309	transcriptional regulator
IC785_RS21360	COG2130	NADP-dependent
IC785_RS21375	COG0582	viral genome integration into host DNA
IC785_RS21420	COG0210	DNA helicase
IC785_RS21440	COG0210	DNA helicase
IC785_RS21530	COG2217	Heavy metal translocating P-type atpase
IC785_RS21535	COG3174	membrane
IC785_RS21540	COG2205	protein histidine kinase activity
IC785_RS21555	COG2132	Multicopper oxidase
IC785_RS21580	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC785_RS21620	COG0789	Transcriptional regulator
IC785_RS21780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC785_RS21985	COG1525	nuclease