locus-tag	class	description
IC800_RS00010	COG0592	DNA-directed DNA polymerase activity
IC800_RS00020	COG0187	DNA topoisomerase II activity
IC800_RS00030	COG0586	Pfam SNARE associated Golgi protein
IC800_RS00035	COG0488	(ABC) transporter
IC800_RS00060	COG0596	Alpha beta hydrolase
IC800_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC800_RS00100	COG0625	glutathione transferase activity
IC800_RS00110	COG0733	neurotransmitter:sodium symporter activity
IC800_RS00150	COG2233	PERMEase
IC800_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS00200	COG2814	Major facilitator Superfamily
IC800_RS00205	COG2814	Major facilitator Superfamily
IC800_RS00210	COG0656	L-ascorbic acid biosynthetic process
IC800_RS00215	COG0583	DNA-binding transcription factor activity
IC800_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC800_RS00235	COG1064	alcohol dehydrogenase
IC800_RS00240	COG2818	Glycosylase
IC800_RS00255	COG1194	a g-specific adenine glycosylase
IC800_RS00270	COG5487	UPF0391 membrane protein
IC800_RS00275	COG2983	Belongs to the UPF0260 family
IC800_RS00280	COG2133	pyrroloquinoline quinone binding
IC800_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC800_RS00290	COG2116	formate transmembrane transporter activity
IC800_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC800_RS00315	COG1335	isochorismatase
IC800_RS00320	COG0385	Bile acid
IC800_RS00325	COG1683	Conserved Protein
IC800_RS00340	COG0346	lactoylglutathione lyase activity
IC800_RS00345	COG0625	glutathione transferase activity
IC800_RS00355	COG1113	amino acid transport
IC800_RS00365	COG0523	cobalamin synthesis protein
IC800_RS00375	COG2188	Transcriptional regulator
IC800_RS00405	COG0010	Belongs to the arginase family
IC800_RS00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC800_RS00460	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC800_RS00465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC800_RS00475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC800_RS00480	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC800_RS00575	COG0534	Mate efflux family protein
IC800_RS00580	COG0436	Aminotransferase
IC800_RS00585	COG2733	membrane
IC800_RS00600	COG2918	glutathione biosynthetic process
IC800_RS00670	COG3150	esterase
IC800_RS00680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC800_RS00690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC800_RS00705	COG2351	hydroxyisourate hydrolase activity
IC800_RS00740	COG3706	GGDEF domain
IC800_RS00755	COG1393	Belongs to the ArsC family
IC800_RS00760	COG0708	Exodeoxyribonuclease III
IC800_RS00780	COG0189	ligase activity
IC800_RS00800	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC800_RS00810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC800_RS00825	COG4942	peptidase
IC800_RS00835	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC800_RS00845	COG2119	membrane
IC800_RS00850	COG4774	siderophore transport
IC800_RS00855	COG0426	domain, Protein
IC800_RS00855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC800_RS00900	COG1902	pentaerythritol trinitrate reductase activity
IC800_RS00905	COG1519	Transferase
IC800_RS00910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC800_RS00915	COG0668	transmembrane transport
IC800_RS00925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC800_RS00930	COG1335	isochorismatase
IC800_RS00935	COG1522	sequence-specific DNA binding
IC800_RS00965	COG3162	membrane
IC800_RS00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC800_RS01000	COG1309	transcriptional regulator
IC800_RS01020	COG0300	oxidoreductase activity
IC800_RS01030	COG0352	thiamine-phosphate diphosphorylase activity
IC800_RS01030	COG0351	phosphomethylpyrimidine kinase
IC800_RS01030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC800_RS01040	COG2814	Major facilitator Superfamily
IC800_RS01055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC800_RS01065	COG1113	amino acid transport
IC800_RS01075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC800_RS01080	COG1012	belongs to the aldehyde dehydrogenase family
IC800_RS01090	COG1335	isochorismatase
IC800_RS01125	COG2814	Major facilitator Superfamily
IC800_RS01130	COG0583	DNA-binding transcription factor activity
IC800_RS01155	COG0667	Aldo Keto reductase
IC800_RS01190	COG1733	regulation of RNA biosynthetic process
IC800_RS01195	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC800_RS01265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC800_RS01280	COG2329	Antibiotic biosynthesis monooxygenase
IC800_RS01310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC800_RS01340	COG0427	acetyl-CoA hydrolase
IC800_RS01365	COG0659	secondary active sulfate transmembrane transporter activity
IC800_RS01370	COG4221	oxidoreductase activity
IC800_RS01385	COG0028	Belongs to the TPP enzyme family
IC800_RS01390	COG0488	(ABC) transporter
IC800_RS01460	COG0833	amino acid
IC800_RS01505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC800_RS01510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC800_RS01525	COG2226	methyltransferase
IC800_RS01575	COG0067	glutamate synthase
IC800_RS01575	COG0069	glutamate synthase activity
IC800_RS01575	COG0070	glutamate synthase
IC800_RS01580	COG0493	'glutamate synthase
IC800_RS01590	COG1704	LemA family
IC800_RS01595	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC800_RS01610	COG3307	-O-antigen
IC800_RS01645	COG0194	GDP metabolic process
IC800_RS01695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC800_RS01705	COG0335	large ribosomal subunit rRNA binding
IC800_RS01715	COG5380	lipid catabolic process
IC800_RS01735	COG5006	permease, DMT superfamily
IC800_RS01740	COG5006	permease, DMT superfamily
IC800_RS01745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC800_RS01750	COG0277	FAD linked oxidase domain protein
IC800_RS01760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC800_RS01765	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC800_RS01785	COG1289	transmembrane transporter activity
IC800_RS01795	COG0628	permease
IC800_RS01800	COG1192	Involved in chromosome partitioning
IC800_RS01835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC800_RS01840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC800_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
IC800_RS01890	COG0583	DNA-binding transcription factor activity
IC800_RS01900	COG0583	DNA-binding transcription factor activity
IC800_RS01920	COG0752	glycyl-tRNA synthetase alpha subunit
IC800_RS01945	COG0617	tRNA 3'-terminal CCA addition
IC800_RS01945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC800_RS01945	COG0517	IMP dehydrogenase activity
IC800_RS01950	COG1983	PspC domain protein
IC800_RS01960	COG1960	acyl-CoA dehydrogenase activity
IC800_RS01975	COG0408	coproporphyrinogen oxidase activity
IC800_RS01995	COG0513	Belongs to the DEAD box helicase family
IC800_RS02005	COG1127	ABC transporter
IC800_RS02010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC800_RS02020	COG2854	intermembrane phospholipid transfer
IC800_RS02030	COG0598	Magnesium transport protein CorA
IC800_RS02040	COG0494	nUDIX hydrolase
IC800_RS02045	COG1040	competence protein
IC800_RS02050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC800_RS02065	COG2937	Belongs to the GPAT DAPAT family
IC800_RS02070	COG1946	Acyl-CoA thioesterase
IC800_RS02075	COG1301	dicarboxylic acid transport
IC800_RS02090	COG1959	2 iron, 2 sulfur cluster binding
IC800_RS02095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC800_RS02095	COG1017	nitric oxide dioxygenase activity
IC800_RS02100	COG0433	COG0433 Predicted ATPase
IC800_RS02105	COG0626	cystathionine gamma-synthase activity
IC800_RS02120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC800_RS02125	COG0088	Forms part of the polypeptide exit tunnel
IC800_RS02260	COG1960	acyl-CoA dehydrogenase activity
IC800_RS02265	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC800_RS02295	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC800_RS02300	COG0339	signal peptide processing
IC800_RS02350	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC800_RS02355	COG2169	Transcriptional regulator
IC800_RS02365	COG1295	ribonuclease BN
IC800_RS02400	COG1702	phosphate starvation-inducible protein PhoH
IC800_RS02410	COG0739	heme binding
IC800_RS02410	COG0741	lytic transglycosylase activity
IC800_RS02410	COG1196	nuclear chromosome segregation
IC800_RS02440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC800_RS02445	COG1183	phosphatidylcholine synthase activity
IC800_RS02495	COG1960	acyl-CoA dehydrogenase activity
IC800_RS02500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC800_RS02505	COG1309	transcriptional regulator
IC800_RS02520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC800_RS02525	COG1960	acyl-CoA dehydrogenase activity
IC800_RS02565	COG2969	positive regulation of protein catabolic process
IC800_RS02575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC800_RS02580	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC800_RS02585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC800_RS02590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC800_RS02595	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC800_RS02615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC800_RS02625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC800_RS02630	COG1408	metallophosphoesterase
IC800_RS02640	COG2199	diguanylate cyclase activity
IC800_RS02700	COG1607	acyl-coa hydrolase
IC800_RS02735	COG2350	Protein conserved in bacteria
IC800_RS02750	COG3781	membrane
IC800_RS02760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC800_RS02765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC800_RS02775	COG1862	Preprotein translocase
IC800_RS02825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC800_RS02840	COG2194	sulfuric ester hydrolase activity
IC800_RS02850	COG0726	polysaccharide deacetylase
IC800_RS02855	COG0463	Glycosyl transferase, family 2
IC800_RS02860	COG0438	transferase activity, transferring glycosyl groups
IC800_RS02900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC800_RS02935	COG1960	acyl-CoA dehydrogenase activity
IC800_RS02940	COG1960	acyl-CoA dehydrogenase activity
IC800_RS02950	COG2205	protein histidine kinase activity
IC800_RS02955	COG0745	RESPONSE REGULATOR receiver
IC800_RS02965	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC800_RS02985	COG2096	Adenosyltransferase
IC800_RS03060	COG0450	alkyl hydroperoxide reductase
IC800_RS03075	COG0477	Major facilitator Superfamily
IC800_RS03080	COG1272	protein, Hemolysin III
IC800_RS03090	COG2153	protein acetylation
IC800_RS03110	COG0183	Belongs to the thiolase family
IC800_RS03120	COG2207	Transcriptional regulator
IC800_RS03140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC800_RS03155	COG0183	Belongs to the thiolase family
IC800_RS03165	COG2885	chlorophyll binding
IC800_RS03165	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC800_RS03175	COG1690	Belongs to the RtcB family
IC800_RS03180	COG0833	amino acid
IC800_RS03190	COG2233	PERMEase
IC800_RS03195	COG1217	gtp-binding protein TYPA
IC800_RS03220	COG2094	Belongs to the DNA glycosylase MPG family
IC800_RS03225	COG4772	TonB-dependent receptor
IC800_RS03230	COG1902	pentaerythritol trinitrate reductase activity
IC800_RS03235	COG0679	Auxin Efflux Carrier
IC800_RS03250	COG0354	folic acid binding
IC800_RS03260	COG3189	MarR family transcriptional regulator
IC800_RS03265	COG2824	Alkylphosphonate utilization operon protein PhnA
IC800_RS03270	COG3422	double-strand break repair
IC800_RS03310	COG0840	transmembrane signaling receptor activity
IC800_RS03325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC800_RS03350	COG2832	Protein of unknown function (DUF454)
IC800_RS03355	COG1376	ErfK ybiS ycfS ynhG family protein
IC800_RS03395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IC800_RS03405	COG1289	transmembrane transporter activity
IC800_RS03410	COG2814	Major facilitator Superfamily
IC800_RS03430	COG1115	amino acid carrier protein
IC800_RS03435	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC800_RS03440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC800_RS03485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC800_RS03495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC800_RS03500	COG1077	Cell shape determining protein MreB Mrl
IC800_RS03505	COG1792	Involved in formation and maintenance of cell shape
IC800_RS03510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC800_RS03515	COG0424	maF-like protein
IC800_RS03520	COG1530	ribonuclease E activity
IC800_RS03530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC800_RS03550	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC800_RS03575	COG2207	Transcriptional regulator
IC800_RS03610	COG3046	protein related to deoxyribodipyrimidine photolyase
IC800_RS03615	COG2816	NAD+ diphosphatase activity
IC800_RS03620	COG1113	amino acid transport
IC800_RS03625	COG2828	Protein conserved in bacteria
IC800_RS03630	COG0142	geranyltranstransferase activity
IC800_RS03635	COG2315	Protein conserved in bacteria
IC800_RS03650	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC800_RS03680	COG2194	sulfuric ester hydrolase activity
IC800_RS03685	COG0745	RESPONSE REGULATOR receiver
IC800_RS03690	COG0642	Histidine kinase
IC800_RS03700	COG0004	ammonium transporteR
IC800_RS03705	COG0583	DNA-binding transcription factor activity
IC800_RS03730	COG0525	valine-tRNA ligase activity
IC800_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS03755	COG0393	Putative heavy-metal-binding
IC800_RS03760	COG1538	Outer membrane efflux protein
IC800_RS03770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS03775	COG0671	phosphoesterase, PA-phosphatase related
IC800_RS03805	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC800_RS03820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC800_RS03820	COG1648	precorrin-2 dehydrogenase activity
IC800_RS03825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC800_RS03830	COG1733	regulation of RNA biosynthetic process
IC800_RS03840	COG0531	amino acid
IC800_RS03855	COG0321	lipoyl(octanoyl) transferase activity
IC800_RS03860	COG2921	Belongs to the UPF0250 family
IC800_RS03895	COG2009	succinate dehydrogenase
IC800_RS03900	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC800_RS03905	COG1053	succinate dehydrogenase
IC800_RS03910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC800_RS03955	COG2354	Protein conserved in bacteria
IC800_RS03960	COG2321	neutral zinc metallopeptidase
IC800_RS03980	COG2843	Capsule synthesis protein
IC800_RS04000	COG0589	response to stress
IC800_RS04020	COG0505	Belongs to the CarA family
IC800_RS04035	COG1534	Rna-binding protein
IC800_RS04045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC800_RS04100	COG0477	Major facilitator Superfamily
IC800_RS04120	COG1597	lipid kinase activity
IC800_RS04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC800_RS04150	COG0584	glycerophosphoryl diester phosphodiesterase
IC800_RS04155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC800_RS04180	COG0741	lytic transglycosylase activity
IC800_RS04200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC800_RS04205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC800_RS04220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS04240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC800_RS04275	COG3811	Belongs to the UPF0386 family
IC800_RS04320	COG1309	transcriptional regulator
IC800_RS04325	COG1902	pentaerythritol trinitrate reductase activity
IC800_RS04330	COG0596	Alpha beta hydrolase
IC800_RS04330	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC800_RS04335	COG0596	Alpha beta hydrolase
IC800_RS04335	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC800_RS04340	COG0596	Alpha beta hydrolase
IC800_RS04350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS04355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC800_RS04360	COG0778	Nitroreductase
IC800_RS04375	COG1929	Belongs to the glycerate kinase type-1 family
IC800_RS04380	COG0243	molybdopterin cofactor binding
IC800_RS04385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC800_RS04415	COG1115	amino acid carrier protein
IC800_RS04420	COG1113	amino acid transport
IC800_RS04430	COG0019	diaminopimelate decarboxylase activity
IC800_RS04445	COG1280	lysine exporter protein (LysE YggA)
IC800_RS04450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC800_RS04470	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC800_RS04480	COG0463	Glycosyl transferase, family 2
IC800_RS04500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS04540	COG1136	(ABC) transporter
IC800_RS04545	COG0658	competence protein
IC800_RS04545	COG2333	competence protein COMEC
IC800_RS04555	COG0616	signal peptide processing
IC800_RS04555	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC800_RS04560	COG0596	Alpha beta hydrolase
IC800_RS04565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC800_RS04575	COG0628	permease
IC800_RS04610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC800_RS04630	COG0823	Involved in the tonB-independent uptake of proteins
IC800_RS04650	COG0824	Thioesterase
IC800_RS04655	COG1473	amidohydrolase
IC800_RS04685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC800_RS04685	COG0047	phosphoribosylformylglycinamidine synthase activity
IC800_RS04690	COG2814	Major facilitator Superfamily
IC800_RS04705	COG1024	Enoyl-CoA hydratase
IC800_RS04710	COG1051	belongs to the nudix hydrolase family
IC800_RS04710	COG1056	cytidyltransferase-related domain
IC800_RS04735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC800_RS04750	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC800_RS04755	COG0602	queuosine metabolic process
IC800_RS04765	COG4625	pathogenesis
IC800_RS04770	COG0583	DNA-binding transcription factor activity
IC800_RS04775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC800_RS04780	COG4208	sulfate ABC transporter
IC800_RS04785	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC800_RS04795	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC800_RS04800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC800_RS04835	COG0481	GTPase activity
IC800_RS04840	COG0681	Belongs to the peptidase S26 family
IC800_RS04855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC800_RS04865	COG1381	Involved in DNA repair and RecF pathway recombination
IC800_RS04870	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC800_RS04880	COG4221	oxidoreductase activity
IC800_RS04905	COG0436	Aminotransferase
IC800_RS04925	COG3706	GGDEF domain
IC800_RS04930	COG0556	nucleotide-excision repair
IC800_RS04985	COG2070	2-Nitropropane dioxygenase
IC800_RS05025	COG1215	transferase activity, transferring glycosyl groups
IC800_RS05050	COG1252	NADH dehydrogenase
IC800_RS05055	COG1686	Belongs to the peptidase S11 family
IC800_RS05070	COG1187	pseudouridine synthase activity
IC800_RS05095	COG0477	Major facilitator Superfamily
IC800_RS05100	COG0583	DNA-binding transcription factor activity
IC800_RS05105	COG1823	symporter activity
IC800_RS05115	COG0612	Peptidase, M16
IC800_RS05140	COG0352	thiamine-phosphate diphosphorylase activity
IC800_RS05175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC800_RS05210	COG3961	Belongs to the TPP enzyme family
IC800_RS05230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC800_RS05235	COG0573	inorganic phosphate transmembrane transporter activity
IC800_RS05245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC800_RS05250	COG0616	signal peptide processing
IC800_RS05265	COG3647	Membrane
IC800_RS05290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC800_RS05295	COG1686	Belongs to the peptidase S11 family
IC800_RS05320	COG0583	DNA-binding transcription factor activity
IC800_RS05325	COG1067	ATP-dependent peptidase activity
IC800_RS05365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC800_RS05370	COG1966	Carbon starvation protein
IC800_RS05375	COG2879	small protein
IC800_RS05415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC800_RS05430	COG2964	Protein conserved in bacteria
IC800_RS05440	COG1741	Belongs to the pirin family
IC800_RS05455	COG3739	integral membrane protein
IC800_RS05475	COG0302	gtp cyclohydrolase
IC800_RS05485	COG2080	2 iron, 2 sulfur cluster binding
IC800_RS05485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC800_RS05495	COG2840	Smr protein MutS2
IC800_RS05510	COG0512	Glutamine amidotransferase of anthranilate synthase
IC800_RS05525	COG0174	glutamine synthetase
IC800_RS05535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC800_RS05570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC800_RS05575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC800_RS05580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC800_RS05600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC800_RS05605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC800_RS05610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC800_RS05625	COG1960	acyl-CoA dehydrogenase activity
IC800_RS05630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC800_RS05635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC800_RS05645	COG2223	nitrite transmembrane transporter activity
IC800_RS05655	COG0024	Methionine aminopeptidase
IC800_RS05660	COG0052	Belongs to the universal ribosomal protein uS2 family
IC800_RS05700	COG2951	lytic endotransglycosylase activity
IC800_RS05705	COG0772	Belongs to the SEDS family
IC800_RS05720	COG0842	Transport permease protein
IC800_RS05765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS05780	COG4215	(ABC) transporter
IC800_RS05785	COG4160	amino acid transport
IC800_RS05790	COG4598	ABC transporter
IC800_RS05800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC800_RS05805	COG0826	peptidase U32
IC800_RS05810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC800_RS05815	COG0384	phenazine biosynthesis protein PhzF
IC800_RS05835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC800_RS05850	COG0642	Histidine kinase
IC800_RS05860	COG0494	nUDIX hydrolase
IC800_RS05870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC800_RS05875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC800_RS05880	COG3139	Protein of unknown function (DUF1315)
IC800_RS05890	COG1301	dicarboxylic acid transport
IC800_RS05895	COG1960	acyl-CoA dehydrogenase activity
IC800_RS05915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC800_RS05925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC800_RS05930	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC800_RS05950	COG1690	Belongs to the RtcB family
IC800_RS05955	COG1234	tRNA 3'-trailer cleavage
IC800_RS05985	COG2363	Small membrane protein
IC800_RS06005	COG0513	Belongs to the DEAD box helicase family
IC800_RS06015	COG0778	Nitroreductase
IC800_RS06075	COG1610	YqeY-like protein
IC800_RS06105	COG2815	serine threonine protein kinase
IC800_RS06105	COG0515	serine threonine protein kinase
IC800_RS06130	COG2831	hemolysin activation secretion protein
IC800_RS06135	COG3210	domain, Protein
IC800_RS06135	COG3210	domain, Protein
IC800_RS06345	COG0786	glutamate:sodium symporter activity
IC800_RS06350	COG0475	glutathione-regulated potassium exporter activity
IC800_RS06350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC800_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS06405	COG1309	transcriptional regulator
IC800_RS06415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC800_RS06415	COG2169	Transcriptional regulator
IC800_RS06430	COG2985	domain, Protein
IC800_RS06455	COG2995	paraquat-inducible protein a
IC800_RS06460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC800_RS06460	COG3008	intermembrane lipid transfer
IC800_RS06470	COG2351	hydroxyisourate hydrolase activity
IC800_RS06485	COG5002	protein histidine kinase activity
IC800_RS06510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC800_RS06525	COG0642	Histidine kinase
IC800_RS06530	COG0745	RESPONSE REGULATOR receiver
IC800_RS06550	COG1794	racemase activity, acting on amino acids and derivatives
IC800_RS06585	COG1301	dicarboxylic acid transport
IC800_RS06600	COG2011	ABC-type metal ion transport system permease component
IC800_RS06605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC800_RS06610	COG1464	Belongs to the NlpA lipoprotein family
IC800_RS06615	COG0151	Belongs to the GarS family
IC800_RS06620	COG0138	bifunctional purine biosynthesis protein purh
IC800_RS06625	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC800_RS06655	COG2308	Evidence 4 Homologs of previously reported genes of
IC800_RS06665	COG1305	Transglutaminase-like
IC800_RS06690	COG0305	Participates in initiation and elongation during chromosome replication
IC800_RS06715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC800_RS06725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC800_RS06760	COG1215	transferase activity, transferring glycosyl groups
IC800_RS06765	COG3658	cytochrome
IC800_RS06775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC800_RS06795	COG2890	protein-(glutamine-N5) methyltransferase activity
IC800_RS06810	COG1960	acyl-CoA dehydrogenase activity
IC800_RS06815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC800_RS06820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC800_RS06845	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC800_RS06850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC800_RS06855	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC800_RS06860	COG2205	protein histidine kinase activity
IC800_RS06865	COG0745	RESPONSE REGULATOR receiver
IC800_RS06870	COG0174	glutamine synthetase
IC800_RS06890	COG0729	surface antigen
IC800_RS06920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC800_RS06925	COG2814	Major facilitator Superfamily
IC800_RS06935	COG0583	DNA-binding transcription factor activity
IC800_RS06970	COG0802	atpase or kinase
IC800_RS06975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC800_RS06985	COG1923	regulation of RNA biosynthetic process
IC800_RS07005	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC800_RS07015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC800_RS07020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC800_RS07020	COG0519	Catalyzes the synthesis of GMP from XMP
IC800_RS07025	COG4302	ethanolamine ammonia-lyase activity
IC800_RS07030	COG4303	Ethanolamine ammonia lyase large subunit
IC800_RS07035	COG0531	amino acid
IC800_RS07055	COG1454	alcohol dehydrogenase
IC800_RS07060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC800_RS07070	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC800_RS07090	COG0308	aminopeptidase N
IC800_RS07145	COG1605	Chorismate mutase
IC800_RS07190	COG4264	IucA IucC family
IC800_RS07200	COG4264	IucA IucC family
IC800_RS07205	COG2423	ornithine cyclodeaminase activity
IC800_RS07210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC800_RS07220	COG0668	transmembrane transport
IC800_RS07270	COG0488	(ABC) transporter
IC800_RS07275	COG0589	response to stress
IC800_RS07300	COG3135	benzoate transporter
IC800_RS07305	COG1522	sequence-specific DNA binding
IC800_RS07315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC800_RS07320	COG0583	DNA-binding transcription factor activity
IC800_RS07330	COG0183	Belongs to the thiolase family
IC800_RS07335	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS07340	COG2030	dehydratase
IC800_RS07345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC800_RS07350	COG3226	Transcriptional regulator
IC800_RS07370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC800_RS07385	COG0824	Thioesterase
IC800_RS07390	COG1454	alcohol dehydrogenase
IC800_RS07415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC800_RS07445	COG0069	glutamate synthase activity
IC800_RS07500	COG0511	ligase activity, forming carbon-carbon bonds
IC800_RS07520	COG1116	anion transmembrane transporter activity
IC800_RS07520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC800_RS07525	COG0745	RESPONSE REGULATOR receiver
IC800_RS07535	COG2146	nitrite reductase [NAD(P)H] activity
IC800_RS07535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC800_RS07540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC800_RS07545	COG0243	molybdopterin cofactor binding
IC800_RS07560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC800_RS07575	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC800_RS07575	COG0315	cyclic pyranopterin monophosphate synthase activity
IC800_RS07580	COG0303	'Molybdopterin
IC800_RS07590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC800_RS07595	COG0697	spore germination
IC800_RS07615	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC800_RS07620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC800_RS07640	COG0596	Alpha beta hydrolase
IC800_RS07690	COG2204	response regulator
IC800_RS07695	COG3852	Histidine kinase
IC800_RS07715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC800_RS07720	COG0575	Belongs to the CDS family
IC800_RS07755	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC800_RS07770	COG2137	regulation of response to DNA damage stimulus
IC800_RS07800	COG1522	sequence-specific DNA binding
IC800_RS07810	COG1113	amino acid transport
IC800_RS07820	COG0659	secondary active sulfate transmembrane transporter activity
IC800_RS07855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC800_RS07855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC800_RS07855	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC800_RS07860	COG1105	Belongs to the carbohydrate kinase PfkB family
IC800_RS07865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC800_RS07865	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC800_RS07895	COG0024	Methionine aminopeptidase
IC800_RS07900	COG0583	DNA-binding transcription factor activity
IC800_RS07910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC800_RS07915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC800_RS07920	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC800_RS07945	COG0552	protein localization to endoplasmic reticulum
IC800_RS07955	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IC800_RS07970	COG4890	Cyd operon protein YbgT
IC800_RS07975	COG1294	oxidase, subunit
IC800_RS07990	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC800_RS08000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC800_RS08005	COG4774	siderophore transport
IC800_RS08020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC800_RS08025	COG0569	domain protein
IC800_RS08030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC800_RS08060	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC800_RS08065	COG0542	response to heat
IC800_RS08090	COG1902	pentaerythritol trinitrate reductase activity
IC800_RS08090	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC800_RS08135	COG2323	membrane
IC800_RS08145	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC800_RS08155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC800_RS08160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC800_RS08165	COG0183	Belongs to the thiolase family
IC800_RS08170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC800_RS08175	COG0596	Alpha beta hydrolase
IC800_RS08180	COG2271	Major facilitator Superfamily
IC800_RS08185	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC800_RS08190	COG3485	protocatechuate 3,4-dioxygenase
IC800_RS08195	COG3485	protocatechuate 3,4-dioxygenase
IC800_RS08200	COG0710	3-dehydroquinate dehydratase activity
IC800_RS08210	COG3659	wide pore channel activity
IC800_RS08215	COG4993	Dehydrogenase
IC800_RS08225	COG2391	methyltransferase activity
IC800_RS08240	COG1414	Transcriptional regulator
IC800_RS08245	COG0583	DNA-binding transcription factor activity
IC800_RS08250	COG1960	acyl-CoA dehydrogenase activity
IC800_RS08275	COG2814	Major facilitator Superfamily
IC800_RS08285	COG0154	amidase activity
IC800_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS08325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC800_RS08335	COG3733	amine oxidase
IC800_RS08350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC800_RS08360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC800_RS08365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC800_RS08375	COG4829	muconolactone delta-isomerase
IC800_RS08380	COG4948	Mandelate Racemase Muconate Lactonizing
IC800_RS08385	COG0583	DNA-binding transcription factor activity
IC800_RS08415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC800_RS08455	COG1309	transcriptional regulator
IC800_RS08470	COG4774	siderophore transport
IC800_RS08485	COG4689	acetoacetate decarboxylase
IC800_RS08495	COG1902	pentaerythritol trinitrate reductase activity
IC800_RS08550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC800_RS08555	COG1120	ATPase activity
IC800_RS08575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC800_RS08715	COG3539	Fimbrial protein
IC800_RS08740	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC800_RS08750	COG0753	catalase activity
IC800_RS08760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC800_RS08765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC800_RS08775	COG2205	protein histidine kinase activity
IC800_RS08780	COG0745	RESPONSE REGULATOR receiver
IC800_RS08785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS08860	COG1535	isochorismatase
IC800_RS08860	COG3433	isochorismatase activity
IC800_RS08865	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC800_RS08870	COG1169	isochorismate synthase
IC800_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS08885	COG3251	PFAM MbtH domain protein
IC800_RS08890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC800_RS08915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC800_RS08920	COG4149	molybdate abc transporter
IC800_RS08925	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC800_RS08935	COG4638	Rieske (2fe-2S)
IC800_RS08940	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC800_RS08945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC800_RS08945	COG0543	2 iron, 2 sulfur cluster binding
IC800_RS08960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC800_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS08995	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS09000	COG2610	gluconate transmembrane transporter activity
IC800_RS09005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC800_RS09030	COG0583	DNA-binding transcription factor activity
IC800_RS09045	COG2031	fatty acid transporter
IC800_RS09050	COG0183	Belongs to the thiolase family
IC800_RS09055	COG0583	DNA-binding transcription factor activity
IC800_RS09060	COG0583	DNA-binding transcription factor activity
IC800_RS09075	COG1027	Aspartate ammonia-lyase
IC800_RS09085	COG0477	Major facilitator Superfamily
IC800_RS09095	COG3708	Transcriptional regulator
IC800_RS09095	COG2207	Transcriptional regulator
IC800_RS09120	COG0730	response to heat
IC800_RS09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC800_RS09135	COG3453	Protein conserved in bacteria
IC800_RS09145	COG3781	membrane
IC800_RS09150	COG1063	alcohol dehydrogenase
IC800_RS09160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC800_RS09165	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC800_RS09170	COG0022	dehydrogenase e1 component
IC800_RS09175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC800_RS09180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC800_RS09195	COG3706	GGDEF domain
IC800_RS09210	COG0133	tryptophan synthase activity
IC800_RS09220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC800_RS09260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC800_RS09285	COG2226	methyltransferase
IC800_RS09335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC800_RS09360	COG0730	response to heat
IC800_RS09365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC800_RS09380	COG0406	alpha-ribazole phosphatase activity
IC800_RS09385	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC800_RS09400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC800_RS09405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC800_RS09420	COG1960	acyl-CoA dehydrogenase activity
IC800_RS09425	COG1960	acyl-CoA dehydrogenase activity
IC800_RS09430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC800_RS09435	COG2207	Transcriptional regulator
IC800_RS09445	COG0776	regulation of translation
IC800_RS09470	COG0822	iron-sulfur transferase activity
IC800_RS09475	COG0316	Belongs to the HesB IscA family
IC800_RS09505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC800_RS09525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC800_RS09530	COG0702	epimerase
IC800_RS09560	COG4172	Belongs to the ABC transporter superfamily
IC800_RS09565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC800_RS09570	COG0601	transmembrane transport
IC800_RS09620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC800_RS09625	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC800_RS09655	COG0776	regulation of translation
IC800_RS09720	COG0084	hydrolase, TatD family'
IC800_RS09740	COG1663	tetraacyldisaccharide 4'-kinase activity
IC800_RS09745	COG1132	(ABC) transporter
IC800_RS09755	COG0811	peptide transport
IC800_RS09760	COG1475	DNA binding
IC800_RS09765	COG1192	Involved in chromosome partitioning
IC800_RS09775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC800_RS09790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC800_RS09815	COG0424	maF-like protein
IC800_RS09820	COG2850	peptidyl-arginine hydroxylation
IC800_RS09830	COG0640	Transcriptional regulator
IC800_RS09840	COG3619	membrane
IC800_RS09845	COG3122	Protein conserved in bacteria
IC800_RS09850	COG1132	(ABC) transporter
IC800_RS09870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC800_RS09875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC800_RS09890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC800_RS09905	COG3698	Phosphodiester glycosidase
IC800_RS09915	COG2353	YceI-like domain
IC800_RS09930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC800_RS09970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC800_RS09970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC800_RS10010	COG0697	spore germination
IC800_RS10020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC800_RS10095	COG1522	sequence-specific DNA binding
IC800_RS10105	COG1126	abc transporter atp-binding protein
IC800_RS10110	COG0765	amino acid transport
IC800_RS10115	COG0765	amino acid transport
IC800_RS10145	COG1464	Belongs to the NlpA lipoprotein family
IC800_RS10150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC800_RS10155	COG2011	ABC-type metal ion transport system permease component
IC800_RS10160	COG0012	GTP binding
IC800_RS10185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC800_RS10225	COG0386	Belongs to the glutathione peroxidase family
IC800_RS10235	COG0436	Aminotransferase
IC800_RS10240	COG1301	dicarboxylic acid transport
IC800_RS10275	COG3634	alkyl hydroperoxide reductase activity
IC800_RS10290	COG0583	DNA-binding transcription factor activity
IC800_RS10295	COG0431	NADPH-dependent FMN reductase
IC800_RS10300	COG0798	PFAM Bile acid sodium symporter
IC800_RS10305	COG0640	Transcriptional regulator
IC800_RS10320	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IC800_RS10330	COG0583	DNA-binding transcription factor activity
IC800_RS10355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC800_RS10360	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC800_RS10365	COG4521	taurine ABC transporter
IC800_RS10375	COG0477	Major facilitator Superfamily
IC800_RS10395	COG1271	oxidase subunit
IC800_RS10400	COG1294	oxidase, subunit
IC800_RS10410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC800_RS10430	COG1346	cytolysis
IC800_RS10440	COG0583	DNA-binding transcription factor activity
IC800_RS10445	COG0625	glutathione transferase activity
IC800_RS10450	COG0625	glutathione transferase activity
IC800_RS10455	COG0583	DNA-binding transcription factor activity
IC800_RS10470	COG1045	serine acetyltransferase
IC800_RS10475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC800_RS10480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC800_RS10485	COG1280	lysine exporter protein (LysE YggA)
IC800_RS10495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC800_RS10500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC800_RS10510	COG0765	amino acid transport
IC800_RS10515	COG0765	amino acid transport
IC800_RS10535	COG0784	Response regulator, receiver
IC800_RS10535	COG2205	protein histidine kinase activity
IC800_RS10555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC800_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS10620	COG0583	DNA-binding transcription factor activity
IC800_RS10630	COG2814	Major facilitator Superfamily
IC800_RS10645	COG0318	PFAM AMP-dependent synthetase and ligase
IC800_RS10650	COG1309	transcriptional regulator
IC800_RS10655	COG1960	acyl-CoA dehydrogenase activity
IC800_RS10660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC800_RS10665	COG1024	Enoyl-CoA hydratase
IC800_RS10670	COG4770	biotin carboxylase activity
IC800_RS10680	COG0583	DNA-binding transcription factor activity
IC800_RS10695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC800_RS10715	COG3842	ATPase activity
IC800_RS10720	COG1840	ABC-type Fe3 transport system, periplasmic component
IC800_RS10740	COG1414	Transcriptional regulator
IC800_RS10750	COG0583	DNA-binding transcription factor activity
IC800_RS10805	COG1073	alpha beta
IC800_RS10810	COG1073	alpha beta
IC800_RS10820	COG0531	amino acid
IC800_RS10825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC800_RS10840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC800_RS10845	COG1309	transcriptional regulator
IC800_RS10860	COG0406	alpha-ribazole phosphatase activity
IC800_RS10870	COG2050	protein possibly involved in aromatic compounds catabolism
IC800_RS10880	COG3327	negative regulation of DNA-templated transcription, initiation
IC800_RS10885	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC800_RS10890	COG0183	Belongs to the thiolase family
IC800_RS10895	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC800_RS10905	COG1024	Enoyl-CoA hydratase
IC800_RS10910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC800_RS10915	COG2151	metal-sulfur cluster biosynthetic enzyme
IC800_RS10920	COG3396	Phenylacetate-CoA oxygenase
IC800_RS10925	COG3460	Phenylacetate-CoA oxygenase
IC800_RS10930	COG3396	Phenylacetate-CoA oxygenase
IC800_RS10935	COG1012	belongs to the aldehyde dehydrogenase family
IC800_RS10935	COG2030	dehydratase
IC800_RS10940	COG1760	l-serine dehydratase
IC800_RS10955	COG0789	Transcriptional regulator
IC800_RS10965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC800_RS10970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC800_RS10985	COG2807	transmembrane transport
IC800_RS10990	COG0590	tRNA wobble adenosine to inosine editing
IC800_RS11125	COG1116	anion transmembrane transporter activity
IC800_RS11140	COG0864	Transcriptional regulator
IC800_RS11155	COG1733	regulation of RNA biosynthetic process
IC800_RS11160	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC800_RS11210	COG0038	chloride channel
IC800_RS11215	COG4770	biotin carboxylase activity
IC800_RS11235	COG1914	H( )-stimulated, divalent metal cation uptake system
IC800_RS11240	COG0583	DNA-binding transcription factor activity
IC800_RS11250	COG1595	DNA-templated transcription, initiation
IC800_RS11260	COG3220	belongs to the UPF0276 family
IC800_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS11290	COG2076	Multidrug Resistance protein
IC800_RS11305	COG3713	MltA-interacting MipA family protein
IC800_RS11310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC800_RS11400	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC800_RS11420	COG1309	transcriptional regulator
IC800_RS11425	COG1278	Cold shock
IC800_RS11435	COG0626	cystathionine gamma-synthase activity
IC800_RS11440	COG1522	sequence-specific DNA binding
IC800_RS11460	COG2814	Major facilitator Superfamily
IC800_RS11475	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IC800_RS11510	COG1271	oxidase subunit
IC800_RS11515	COG1294	oxidase, subunit
IC800_RS11525	COG1469	GTP cyclohydrolase I activity
IC800_RS11545	COG1560	Kdo2-lipid A biosynthetic process
IC800_RS11590	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC800_RS11630	COG1538	Outer membrane efflux protein
IC800_RS11635	COG1137	ATPase activity
IC800_RS11640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC800_RS11650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC800_RS11655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC800_RS11655	COG0517	IMP dehydrogenase activity
IC800_RS11710	COG1686	Belongs to the peptidase S11 family
IC800_RS11730	COG3561	AntA/AntB antirepressor
IC800_RS11805	COG3566	protein conserved in bacteria
IC800_RS11820	COG3567	Phage-associated protein, HI1409 family
IC800_RS11825	COG5410	chromosome segregation
IC800_RS11990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC800_RS12005	COG0667	Aldo Keto reductase
IC800_RS12015	COG2814	Major facilitator Superfamily
IC800_RS12045	COG1278	Cold shock
IC800_RS12050	COG1280	lysine exporter protein (LysE YggA)
IC800_RS12080	COG1570	exodeoxyribonuclease VII activity
IC800_RS12165	COG2871	sodium ion transport
IC800_RS12175	COG0583	DNA-binding transcription factor activity
IC800_RS12185	COG4638	Rieske (2fe-2S)
IC800_RS12190	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC800_RS12195	COG0633	Ferredoxin
IC800_RS12195	COG0543	2 iron, 2 sulfur cluster binding
IC800_RS12200	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS12205	COG3135	benzoate transporter
IC800_RS12210	COG2814	Major facilitator Superfamily
IC800_RS12240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC800_RS12250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IC800_RS12260	COG3634	alkyl hydroperoxide reductase activity
IC800_RS12280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC800_RS12285	COG0625	glutathione transferase activity
IC800_RS12330	COG0542	response to heat
IC800_RS12345	COG1765	OsmC-like protein
IC800_RS12355	COG0667	Aldo Keto reductase
IC800_RS12370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC800_RS12385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC800_RS12395	COG0527	aspartate kinase activity
IC800_RS12405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC800_RS12415	COG3038	cytochrome b561
IC800_RS12420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC800_RS12425	COG2252	PERMEase
IC800_RS12435	COG2072	flavoprotein involved in K transport
IC800_RS12450	COG1741	Belongs to the pirin family
IC800_RS12455	COG1309	transcriptional regulator
IC800_RS12475	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC800_RS12525	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC800_RS12540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC800_RS12555	COG2814	Major facilitator Superfamily
IC800_RS12560	COG1024	Enoyl-CoA hydratase
IC800_RS12565	COG1012	belongs to the aldehyde dehydrogenase family
IC800_RS12575	COG1960	acyl-CoA dehydrogenase activity
IC800_RS12615	COG1113	amino acid transport
IC800_RS12635	COG1012	belongs to the aldehyde dehydrogenase family
IC800_RS12655	COG0531	amino acid
IC800_RS12670	COG1113	amino acid transport
IC800_RS12730	COG3209	COG3209 Rhs family protein
IC800_RS12815	COG4269	membrane
IC800_RS12835	COG0583	DNA-binding transcription factor activity
IC800_RS12845	COG0251	oxidation-reduction process
IC800_RS12865	COG1902	pentaerythritol trinitrate reductase activity
IC800_RS12865	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC800_RS12885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC800_RS12915	COG4172	Belongs to the ABC transporter superfamily
IC800_RS12920	COG4239	(ABC) transporter, permease
IC800_RS12925	COG4174	ABC transporter (Permease)
IC800_RS12930	COG4166	transmembrane transport
IC800_RS12935	COG0741	lytic transglycosylase activity
IC800_RS12935	COG1388	LysM domain
IC800_RS12935	COG0741	lytic transglycosylase activity
IC800_RS12935	COG1388	LysM domain
IC800_RS12980	COG0583	DNA-binding transcription factor activity
IC800_RS12985	COG1279	arginine transmembrane transporter activity
IC800_RS13005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC800_RS13010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC800_RS13015	COG0006	proline dipeptidase activity
IC800_RS13050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC800_RS13110	COG3384	dioxygenase
IC800_RS13120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC800_RS13125	COG2878	Part of a membrane complex involved in electron transport
IC800_RS13130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC800_RS13155	COG0768	penicillin binding
IC800_RS13160	COG0742	ribosomal rna small subunit methyltransferase
IC800_RS13180	COG0830	nickel cation binding
IC800_RS13230	COG1253	flavin adenine dinucleotide binding
IC800_RS13235	COG2851	Citrate transporter
IC800_RS13285	COG1773	rubredoxin
IC800_RS13290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC800_RS13300	COG0583	DNA-binding transcription factor activity
IC800_RS13325	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC800_RS13375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC800_RS13395	COG0306	phosphate transporter
IC800_RS13430	COG2223	nitrite transmembrane transporter activity
IC800_RS13435	COG2207	Transcriptional regulator
IC800_RS13440	COG2066	Belongs to the glutaminase family
IC800_RS13445	COG0242	peptide deformylase activity
IC800_RS13450	COG0477	Major facilitator Superfamily
IC800_RS13460	COG0028	Belongs to the TPP enzyme family
IC800_RS13475	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS13480	COG2267	carboxylic ester hydrolase activity
IC800_RS13490	COG2271	Major facilitator Superfamily
IC800_RS13525	COG1414	Transcriptional regulator
IC800_RS13555	COG1024	Enoyl-CoA hydratase
IC800_RS13565	COG1215	transferase activity, transferring glycosyl groups
IC800_RS13570	COG0726	polysaccharide deacetylase
IC800_RS13570	COG1649	PFAM Uncharacterised BCR, COG1649
IC800_RS13580	COG4681	YaeQ
IC800_RS13590	COG0523	cobalamin synthesis protein
IC800_RS13610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC800_RS13615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC800_RS13620	COG1309	transcriptional regulator
IC800_RS13645	COG2040	homocysteine
IC800_RS13670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC800_RS13675	COG0477	Major facilitator Superfamily
IC800_RS13685	COG1404	Belongs to the peptidase S8 family
IC800_RS13740	COG1401	restriction endodeoxyribonuclease activity
IC800_RS13750	COG0405	Gamma-glutamyltransferase
IC800_RS13755	COG2814	Major facilitator Superfamily
IC800_RS13765	COG2050	protein possibly involved in aromatic compounds catabolism
IC800_RS13780	COG1090	epimerase
IC800_RS13810	COG1968	undecaprenyl-diphosphatase activity
IC800_RS13830	COG0735	belongs to the Fur family
IC800_RS13835	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC800_RS13840	COG2914	Belongs to the UPF0125 (RnfH) family
IC800_RS13855	COG0121	glutamine amidotransferase
IC800_RS13870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC800_RS13880	COG0210	DNA helicase
IC800_RS13885	COG2885	chlorophyll binding
IC800_RS13890	COG0204	Acyl-transferase
IC800_RS13905	COG2894	cell division
IC800_RS13920	COG1280	lysine exporter protein (LysE YggA)
IC800_RS13925	COG1674	ftsk spoiiie
IC800_RS13930	COG0492	ferredoxin-NADP+ reductase activity
IC800_RS13935	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC800_RS13945	COG0456	acetyltransferase
IC800_RS13965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC800_RS13975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC800_RS14035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC800_RS14085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC800_RS14110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC800_RS14140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC800_RS14150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC800_RS14150	COG0351	phosphomethylpyrimidine kinase
IC800_RS14150	COG0352	thiamine-phosphate diphosphorylase activity
IC800_RS14155	COG1652	LysM domain
IC800_RS14180	COG1399	metal-binding, possibly nucleic acid-binding protein
IC800_RS14185	COG3101	peptidyl-lysine hydroxylation
IC800_RS14190	COG0009	L-threonylcarbamoyladenylate synthase
IC800_RS14195	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC800_RS14200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC800_RS14215	COG4106	trans-aconitate 2-methyltransferase activity
IC800_RS14230	COG2226	methyltransferase
IC800_RS14230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC800_RS14230	COG0596	Alpha beta hydrolase
IC800_RS14235	COG1877	trehalose-phosphatase activity
IC800_RS14240	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC800_RS14300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IC800_RS14315	COG1196	nuclear chromosome segregation
IC800_RS14325	COG0730	response to heat
IC800_RS14340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC800_RS14350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC800_RS14395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC800_RS14400	COG0489	protein tyrosine kinase activity
IC800_RS14410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC800_RS14410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC800_RS14455	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC800_RS14460	COG2081	HI0933 family
IC800_RS14470	COG0668	transmembrane transport
IC800_RS14490	COG0583	DNA-binding transcription factor activity
IC800_RS14515	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC800_RS14520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC800_RS14535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC800_RS14550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC800_RS14575	COG3706	GGDEF domain
IC800_RS14590	COG0745	RESPONSE REGULATOR receiver
IC800_RS14610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC800_RS14645	COG0438	transferase activity, transferring glycosyl groups
IC800_RS14660	COG0110	maltose O-acetyltransferase activity
IC800_RS14715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC800_RS14720	COG0583	DNA-binding transcription factor activity
IC800_RS14770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC800_RS14785	COG0583	DNA-binding transcription factor activity
IC800_RS14805	COG0583	DNA-binding transcription factor activity
IC800_RS14840	COG1309	transcriptional regulator
IC800_RS14850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC800_RS14855	COG2814	Major facilitator Superfamily
IC800_RS14860	COG1960	acyl-CoA dehydrogenase activity
IC800_RS14870	COG1063	alcohol dehydrogenase
IC800_RS14905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC800_RS14910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC800_RS14925	COG3667	copper resistance
IC800_RS14945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC800_RS14970	COG1214	PFAM Peptidase M22, glycoprotease
IC800_RS15030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC800_RS15035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC800_RS15040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC800_RS15100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC800_RS15110	COG1846	Transcriptional regulator
IC800_RS15115	COG1764	response to oxidative stress
IC800_RS15155	COG0037	tRNA processing
IC800_RS15165	COG0248	Ppx GppA phosphatase
IC800_RS15195	COG0072	phenylalanine-tRNA ligase activity
IC800_RS15225	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC800_RS15235	COG1238	metal cluster binding
IC800_RS15240	COG0625	glutathione transferase activity
IC800_RS15255	COG0318	PFAM AMP-dependent synthetase and ligase
IC800_RS15260	COG3028	Belongs to the UPF0307 family
IC800_RS15285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC800_RS15290	COG0617	tRNA 3'-terminal CCA addition
IC800_RS15295	COG1555	photosystem II stabilization
IC800_RS15300	COG3956	TIGRFAM MazG family protein
IC800_RS15310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC800_RS15330	COG2205	protein histidine kinase activity
IC800_RS15330	COG5002	protein histidine kinase activity
IC800_RS15330	COG0784	Response regulator, receiver
IC800_RS15335	COG1024	Enoyl-CoA hydratase
IC800_RS15340	COG2084	Dehydrogenase
IC800_RS15345	COG3622	Belongs to the hyi family
IC800_RS15380	COG0697	spore germination
IC800_RS15390	COG2814	Major facilitator Superfamily
IC800_RS15550	COG3646	Phage regulatory protein
IC800_RS15590	COG0629	single-stranded DNA binding
IC800_RS15620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC800_RS15640	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC800_RS15650	COG0084	hydrolase, TatD family'
IC800_RS15665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC800_RS15690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC800_RS15695	COG0440	acetolactate synthase activity
IC800_RS15700	COG0028	Belongs to the TPP enzyme family
IC800_RS15725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC800_RS15730	COG0577	efflux transmembrane transporter activity
IC800_RS15730	COG1136	(ABC) transporter
IC800_RS15735	COG1538	Outer membrane efflux protein
IC800_RS15750	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC800_RS15755	COG1162	GTPase activity
IC800_RS15765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC800_RS15805	COG1426	Protein conserved in bacteria
IC800_RS15840	COG0793	Belongs to the peptidase S41A family
IC800_RS15865	COG1012	belongs to the aldehyde dehydrogenase family
IC800_RS15870	COG3265	gluconokinase activity
IC800_RS15880	COG0800	Aldolase
IC800_RS15890	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC800_RS15895	COG0857	belongs to the CobB CobQ family
IC800_RS15895	COG0280	phosphate acetyltransferase
IC800_RS15900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC800_RS15900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC800_RS15920	COG0740	serine-type endopeptidase activity
IC800_RS15930	COG4774	siderophore transport
IC800_RS15950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC800_RS15950	COG2813	Specifically methylates the guanine in position
IC800_RS16045	COG0788	formyltetrahydrofolate deformylase activity
IC800_RS16070	COG4651	solute:proton antiporter activity
IC800_RS16070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC800_RS16090	COG0724	RNA recognition motif
IC800_RS16095	COG0210	DNA helicase
IC800_RS16120	COG1733	regulation of RNA biosynthetic process
IC800_RS16130	COG2900	Belongs to the SlyX family
IC800_RS16135	COG0488	(ABC) transporter
IC800_RS16145	COG1280	lysine exporter protein (LysE YggA)
IC800_RS16150	COG1560	Kdo2-lipid A biosynthetic process
IC800_RS16160	COG1301	dicarboxylic acid transport
IC800_RS16215	COG0473	3-isopropylmalate dehydrogenase activity
IC800_RS16240	COG0583	DNA-binding transcription factor activity
IC800_RS16285	COG0583	DNA-binding transcription factor activity
IC800_RS16295	COG0625	glutathione transferase activity
IC800_RS16300	COG2378	regulation of single-species biofilm formation
IC800_RS16315	COG1530	ribonuclease E activity
IC800_RS16320	COG0318	PFAM AMP-dependent synthetase and ligase
IC800_RS16335	COG0583	DNA-binding transcription factor activity
IC800_RS16340	COG4221	oxidoreductase activity
IC800_RS16345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC800_RS16355	COG0534	Mate efflux family protein
IC800_RS16370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC800_RS16400	COG0493	'glutamate synthase
IC800_RS16400	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC800_RS16410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC800_RS16430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC800_RS16440	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC800_RS16440	COG0644	oxidoreductase
IC800_RS16455	COG4535	Mg2 and Co2 transporter CorC
IC800_RS16465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC800_RS16495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC800_RS16495	COG0475	glutathione-regulated potassium exporter activity
IC800_RS16500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC800_RS16515	COG0789	Transcriptional regulator
IC800_RS16520	COG0598	Magnesium transport protein CorA
IC800_RS16525	COG1185	polyribonucleotide nucleotidyltransferase activity
IC800_RS16540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC800_RS16545	COG1074	ATP-dependent DNA helicase activity
IC800_RS16550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC800_RS16575	COG2226	methyltransferase
IC800_RS16590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC800_RS16620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC800_RS16620	COG2111	Na H antiporter
IC800_RS16625	COG1006	Multisubunit Na H antiporter MnhC subunit
IC800_RS16630	COG0651	ATP synthesis coupled electron transport
IC800_RS16635	COG1863	multisubunit Na H antiporter MnhE subunit
IC800_RS16640	COG2212	antiporter activity
IC800_RS16645	COG1320	monovalent cation:proton antiporter activity
IC800_RS16650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC800_RS16660	COG0195	Participates in both transcription termination and antitermination
IC800_RS16710	COG0237	dephospho-CoA kinase activity
IC800_RS16720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC800_RS16735	COG0497	DNA recombination
IC800_RS16745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC800_RS16760	COG1289	transmembrane transporter activity
IC800_RS16775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC800_RS16845	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC800_RS16860	COG0326	Molecular chaperone. Has ATPase activity
IC800_RS16875	COG2056	Na+-H+ antiporter family
IC800_RS16880	COG0596	Alpha beta hydrolase
IC800_RS16975	COG0546	phosphoglycolate phosphatase activity
IC800_RS16980	COG1716	ATPase activity
IC800_RS17025	COG0181	hydroxymethylbilane synthase activity
IC800_RS17055	COG1538	Outer membrane efflux protein
IC800_RS17065	COG0697	spore germination
IC800_RS17085	COG0494	nUDIX hydrolase
IC800_RS17095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC800_RS17105	COG0772	Belongs to the SEDS family
IC800_RS17130	COG4974	Belongs to the 'phage' integrase family
IC800_RS17135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC800_RS17145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC800_RS17155	COG2197	response regulator
IC800_RS17170	COG0793	Belongs to the peptidase S41A family
IC800_RS17175	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC800_RS17180	COG0795	lipopolysaccharide-transporting ATPase activity
IC800_RS17185	COG0795	lipopolysaccharide-transporting ATPase activity
IC800_RS17220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC800_RS17220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC800_RS17230	COG0004	ammonium transporteR
IC800_RS17235	COG0347	Belongs to the P(II) protein family
IC800_RS17245	COG0606	chelatase, subunit chli
IC800_RS17250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC800_RS17255	COG0235	Class ii aldolase
IC800_RS17260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC800_RS17275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC800_RS17290	COG0318	PFAM AMP-dependent synthetase and ligase
IC800_RS17300	COG0477	Major facilitator Superfamily
IC800_RS17305	COG2860	membrane
IC800_RS17315	COG1253	flavin adenine dinucleotide binding
IC800_RS17325	COG2814	Major facilitator Superfamily
IC800_RS17335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC800_RS17370	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC800_RS17385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC800_RS17420	COG1309	transcriptional regulator
IC800_RS17455	COG0758	DNA mediated transformation
IC800_RS17465	COG0697	spore germination
IC800_RS17470	COG1309	transcriptional regulator
IC800_RS17485	COG0386	Belongs to the glutathione peroxidase family
IC800_RS17495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC800_RS17500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC800_RS17555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC800_RS17560	COG1280	lysine exporter protein (LysE YggA)
IC800_RS17565	COG2837	iron assimilation
IC800_RS17575	COG0281	malic enzyme
IC800_RS17610	COG0735	belongs to the Fur family
IC800_RS17625	COG0519	Catalyzes the synthesis of GMP from XMP
IC800_RS17625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC800_RS17630	COG4399	Belongs to the UPF0754 family
IC800_RS17630	COG4399	Belongs to the UPF0754 family
IC800_RS17635	COG2259	Doxx family
IC800_RS17640	COG0586	Pfam SNARE associated Golgi protein
IC800_RS17665	COG0271	Belongs to the BolA IbaG family
IC800_RS17705	COG0300	oxidoreductase activity
IC800_RS17705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC800_RS17705	COG4221	oxidoreductase activity
IC800_RS17705	COG3321	synthase
IC800_RS17730	COG3916	Acyl-homoserine-lactone synthase
IC800_RS17735	COG0477	Major facilitator Superfamily
IC800_RS17740	COG1024	Enoyl-CoA hydratase
IC800_RS17745	COG1024	Enoyl-CoA hydratase
IC800_RS17750	COG1960	acyl-CoA dehydrogenase activity
IC800_RS17755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC800_RS17775	COG1113	amino acid transport
IC800_RS17780	COG1113	amino acid transport
IC800_RS17785	COG0251	oxidation-reduction process
IC800_RS17825	COG0564	pseudouridine synthase activity
IC800_RS17895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC800_RS17910	COG1802	Transcriptional regulator
IC800_RS17915	COG1448	Aminotransferase
IC800_RS17920	COG0277	FAD linked oxidase domain protein
IC800_RS17930	COG2186	Transcriptional regulator
IC800_RS17940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC800_RS17970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC800_RS17975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC800_RS18005	COG2244	polysaccharide biosynthetic process
IC800_RS18015	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC800_RS18020	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC800_RS18030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC800_RS18035	COG1596	polysaccharide export
IC800_RS18065	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC800_RS18120	COG0546	phosphoglycolate phosphatase activity
IC800_RS18125	COG1028	Short-chain dehydrogenase reductase Sdr
IC800_RS18140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC800_RS18140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC800_RS18145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC800_RS18150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC800_RS18155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC800_RS18160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC800_RS18165	COG1116	anion transmembrane transporter activity
IC800_RS18170	COG1309	transcriptional regulator
IC800_RS18175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC800_RS18190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC800_RS18200	COG1047	Peptidyl-prolyl cis-trans
IC800_RS18240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC800_RS18245	COG0657	acetylesterase activity
IC800_RS18295	COG2951	lytic endotransglycosylase activity
IC800_RS18315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC800_RS18325	COG0671	phosphoesterase, PA-phosphatase related
IC800_RS18330	COG0861	Integral membrane protein TerC family
IC800_RS18340	COG0402	S-adenosylhomocysteine deaminase activity
IC800_RS18355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC800_RS18370	COG0706	membrane insertase activity
IC800_RS18390	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IC800_RS18460	COG0582	viral genome integration into host DNA
IC800_RS18490	COG2026	Addiction module toxin, RelE StbE family
IC800_RS18500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC800_RS18540	COG2076	Multidrug Resistance protein
IC800_RS18575	COG1396	sequence-specific DNA binding
IC800_RS18655	COG4683	PFAM Phage derived protein Gp49-like (DUF891)