locus-tag	class	description
G8D99_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G8D99_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D99_RS00025	ENOG4108821	RND type efflux pump
G8D99_RS00030	ENOG4108821	RND type efflux pump
G8D99_RS00035	ENOG4108821	RND type efflux pump
G8D99_RS00050	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
G8D99_RS00055	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G8D99_RS00060	ENOG4105C5H	ABC transporter
G8D99_RS00075	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G8D99_RS00095	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
G8D99_RS00150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8D99_RS00225	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G8D99_RS00230	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G8D99_RS00235	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G8D99_RS00240	ENOG4105DTN	riboflavin biosynthesis protein ribF
G8D99_RS00255	ENOG4108W9H	Tetr family transcriptional regulator
G8D99_RS00260	ENOG4108VM9	ABC, transporter
G8D99_RS00265	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8D99_RS00270	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
G8D99_RS00275	ENOG4105GVF	(ABC) transporter
G8D99_RS00280	ENOG4105GVF	(ABC) transporter
G8D99_RS00285	ENOG4107QZM	n-acetylglutamate synthase
G8D99_RS00315	ENOG4105F27	Major Facilitator
G8D99_RS00330	ENOG4108R3E	Dna-3-methyladenine glycosylase i
G8D99_RS00345	ENOG4105CEN	a g-specific adenine glycosylase
G8D99_RS00365	ENOG4108ZZ3	UPF0260 protein
G8D99_RS00375	ENOG4105D1H	recombination factor protein RarA
G8D99_RS00390	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G8D99_RS00395	ENOG4108RWI	nicotinamidase
G8D99_RS00400	ENOG4105C09	Bile acid
G8D99_RS00405	ENOG4105EWC	Purine nucleoside phosphorylase
G8D99_RS00410	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G8D99_RS00420	ENOG4108ZAI	phosphatidylglycerophosphatase a
G8D99_RS00425	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G8D99_RS00435	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G8D99_RS00440	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G8D99_RS00450	ENOG4105EAC	phosphoserine phosphatase
G8D99_RS00480	ENOG4105KHC	sulfurtransferase
G8D99_RS00490	ENOG4105BZU	Histidine kinase
G8D99_RS00495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G8D99_RS00515	ENOG4105IJJ	transcriptional regulator, crp fnr family
G8D99_RS00535	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
G8D99_RS00540	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8D99_RS00545	ENOG4105D7T	ABC transporter
G8D99_RS00555	ENOG4107QJQ	Mate efflux family protein
G8D99_RS00560	ENOG4105CHM	Aminotransferase
G8D99_RS00565	ENOG4106BRA	Membrane
G8D99_RS00580	ENOG4105D9M	gamma-glutamylcysteine synthetase
G8D99_RS00585	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
G8D99_RS00600	ENOG4105IPS	esterase
G8D99_RS00605	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D99_RS00610	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
G8D99_RS00615	ENOG4105C32	Amino acid ABC transporter (Permease)
G8D99_RS00625	ENOG4105C0Z	ABC transporter
G8D99_RS00630	ENOG4108IV0	ABC, transporter
G8D99_RS00650	ENOG4105DHG	Allantoate amidinohydrolase
G8D99_RS00655	ENOG41061H0	Monooxygenase
G8D99_RS00660	ENOG4108Z7F	N-acetyltransferase
G8D99_RS00675	ENOG4105VT2	5-hydroxyisourate hydrolase
G8D99_RS00710	ENOG4105BZU	Histidine kinase
G8D99_RS00725	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
G8D99_RS00730	ENOG4105CGK	Exodeoxyribonuclease III
G8D99_RS00735	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G8D99_RS00750	ENOG4105D7Z	glutathione synthase
G8D99_RS00760	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G8D99_RS00765	ENOG4105DFU	Cell wall formation (By similarity)
G8D99_RS00775	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G8D99_RS00780	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G8D99_RS00785	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G8D99_RS00790	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8D99_RS00805	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G8D99_RS00810	ENOG4107QSN	dihydrolipoamide acetyltransferase
G8D99_RS00830	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G8D99_RS00835	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G8D99_RS00845	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G8D99_RS00870	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8D99_RS00875	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G8D99_RS00890	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G8D99_RS00895	ENOG4107T8P	acyl-Coa dehydrogenase
G8D99_RS00905	ENOG4105FBW	Monooxygenase
G8D99_RS00910	ENOG4108UZX	fmn reductase
G8D99_RS00915	ENOG4108W5X	Transcriptional Regulator, LuxR family
G8D99_RS00925	ENOG4105BZU	Histidine kinase
G8D99_RS00930	ENOG41062QD	Membrane
G8D99_RS00935	ENOG4107QN1	sodium solute
G8D99_RS00945	ENOG4108HWY	Beta-lactamase
G8D99_RS00950	ENOG4105BZU	Histidine kinase
G8D99_RS00960	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G8D99_RS00965	ENOG4105RA2	Membrane
G8D99_RS00970	ENOG4105ETU	transcriptional activator (TenA
G8D99_RS00980	ENOG4107RDB	Major Facilitator
G8D99_RS00985	ENOG4108UUM	single-stranded DNA-binding protein
G8D99_RS00990	ENOG4105D3R	alkyl hydroperoxide reductase
G8D99_RS00995	ENOG4105CC0	LysR family Transcriptional regulator
G8D99_RS01000	ENOG4105CHJ	isochorismatase hydrolase
G8D99_RS01005	ENOG4105EUB	pirin domain protein
G8D99_RS01035	ENOG4105DFH	Transport of potassium into the cell (By similarity)
G8D99_RS01055	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
G8D99_RS01115	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G8D99_RS01120	ENOG410631K	Membrane
G8D99_RS01145	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G8D99_RS01185	ENOG4105CYC	Transferase
G8D99_RS01190	ENOG4105E0F	Histidine kinase
G8D99_RS01210	ENOG4105CHH	sulfate transporter
G8D99_RS01220	ENOG4105PDP	Short chain dehydrogenase
G8D99_RS01230	ENOG4105C5H	ABC transporter
G8D99_RS01265	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G8D99_RS01270	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G8D99_RS01290	ENOG4105CJN	penicillin-binding protein
G8D99_RS01295	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G8D99_RS01300	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G8D99_RS01305	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
G8D99_RS01310	ENOG4105DHI	Methyltransferase
G8D99_RS01315	ENOG4108JQC	penicillin-binding protein 1A
G8D99_RS01340	ENOG4105E4G	Type IV pilus
G8D99_RS01345	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G8D99_RS01360	ENOG4105CBC	glutamate synthase
G8D99_RS01365	ENOG4105BZ8	glutamate synthase
G8D99_RS01375	ENOG4108R6K	riboflavin synthase, subunit alpha
G8D99_RS01380	ENOG4105KJM	monovalent cation h antiporter subunit g
G8D99_RS01385	ENOG4105W4C	monovalent cation H antiporter subunit F
G8D99_RS01390	ENOG4105SC1	monovalent cation H antiporter subunit E
G8D99_RS01395	ENOG4107R4Z	monovalent cation h antiporter subunit d
G8D99_RS01400	ENOG4108ZE9	Monovalent cation H antiporter subunit C
G8D99_RS01405	ENOG4105D65	subunit l
G8D99_RS01420	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G8D99_RS01435	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G8D99_RS01455	ENOG4105CSR	polyphosphate kinase 2
G8D99_RS01465	ENOG4105DSY	exodeoxyribonuclease V, gamma
G8D99_RS01470	ENOG4107QKA	exodeoxyribonuclease V beta
G8D99_RS01475	ENOG4107QYX	exodeoxyribonuclease v alpha
G8D99_RS01490	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G8D99_RS01495	ENOG4107QUT	magnesium and cobalt transport protein CorA
G8D99_RS01500	ENOG4105Z2P	Protein of unknown function (DUF465)
G8D99_RS01515	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G8D99_RS01520	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G8D99_RS01525	ENOG4105C25	Primosomal protein n'
G8D99_RS01530	ENOG4105D7Q	type ii secretion system
G8D99_RS01535	ENOG4108VAU	general secretion pathway protein G
G8D99_RS01545	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G8D99_RS01550	ENOG4108JU5	Magnesium and cobalt efflux protein
G8D99_RS01560	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
G8D99_RS01620	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G8D99_RS01630	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G8D99_RS01645	ENOG4105C5X	domain protein
G8D99_RS01650	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
G8D99_RS01675	ENOG4105WMR	Protein CrcB homolog
G8D99_RS01680	ENOG4105NRA	50s ribosomal protein l31 type b
G8D99_RS01690	ENOG4107QI1	Mate efflux family protein
G8D99_RS01700	ENOG4105CSA	Coproporphyrinogen iii oxidase
G8D99_RS01715	ENOG4105CSU	acyl-Coa dehydrogenase
G8D99_RS01730	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G8D99_RS01740	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G8D99_RS01745	ENOG4105ECY	inositol monophosphatase
G8D99_RS01750	ENOG4105C1J	atp-dependent rna helicase
G8D99_RS01755	ENOG4105DHJ	ABC, transporter
G8D99_RS01760	ENOG4105CY3	ABC transporter, permease
G8D99_RS01765	ENOG4107PE3	Mammalian cell entry related domain protein
G8D99_RS01780	ENOG4105D7N	magnesium and cobalt transport protein CorA
G8D99_RS01785	ENOG4108URH	decarboxylase
G8D99_RS01795	ENOG4105MJ2	Competence protein
G8D99_RS01800	ENOG4105CB5	ATP-dependent DNA helicase recG
G8D99_RS01805	ENOG4105E55	glycerol-3-phosphate acyltransferase
G8D99_RS01810	ENOG4105C29	acyl-CoA thioesterase
G8D99_RS01830	ENOG4105DZG	Dehydrogenase
G8D99_RS01835	ENOG4105KPV	Transcriptional regulator
G8D99_RS01845	ENOG4105D7A	ATP-binding protein
G8D99_RS01850	ENOG4105C28	cystathionine
G8D99_RS01860	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G8D99_RS01870	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G8D99_RS01885	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G8D99_RS01915	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G8D99_RS01930	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G8D99_RS01935	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G8D99_RS01940	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G8D99_RS01950	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G8D99_RS01960	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G8D99_RS01965	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G8D99_RS01975	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G8D99_RS01985	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G8D99_RS01990	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G8D99_RS01995	ENOG4108ZT0	50S ribosomal protein l17
G8D99_RS02000	ENOG4105CT3	Monooxygenase
G8D99_RS02005	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS02030	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G8D99_RS02040	ENOG4105VKU	nucleicacid-binding protein
G8D99_RS02045	ENOG4105DGW	oligopeptidase A
G8D99_RS02050	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G8D99_RS02085	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
G8D99_RS02090	ENOG4107S2Z	UPF0761 membrane protein
G8D99_RS02095	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G8D99_RS02105	ENOG4105GVF	(ABC) transporter
G8D99_RS02135	ENOG4105D64	Mechanosensitive ion channel
G8D99_RS02145	ENOG4105C9A	Phoh family
G8D99_RS02150	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G8D99_RS02155	ENOG4105E4C	Lytic transglycosylase catalytic
G8D99_RS02190	ENOG4105D6S	protein involved in catabolism of external DNA
G8D99_RS02195	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G8D99_RS02230	ENOG4107QN2	dihydrolipoyl dehydrogenase
G8D99_RS02260	ENOG4105NAU	thioesterase Superfamily protein
G8D99_RS02280	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
G8D99_RS02285	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
G8D99_RS02295	ENOG4105K9H	YciI-like protein
G8D99_RS02305	ENOG4105DB7	PHP domain protein
G8D99_RS02310	ENOG4105FFC	UPF0187 protein
G8D99_RS02315	ENOG4105W5Q	DNA repair protein (RadC
G8D99_RS02320	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G8D99_RS02330	ENOG4105VW4	glutaredoxin 3
G8D99_RS02340	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G8D99_RS02345	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G8D99_RS02360	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G8D99_RS02365	ENOG4105CS6	Rhs element vgr protein
G8D99_RS02380	ENOG4105CNA	YD repeat protein
G8D99_RS02415	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D99_RS02420	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G8D99_RS02425	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G8D99_RS02450	ENOG4105C7K	acetolactate synthase
G8D99_RS02455	ENOG4108ZP8	Acetolactate synthase small subunit
G8D99_RS02475	ENOG4105WVQ	Fe-S assembly protein IscX
G8D99_RS02495	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
G8D99_RS02515	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G8D99_RS02535	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G8D99_RS02540	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G8D99_RS02545	ENOG4105VIE	preprotein translocase, subunit YajC
G8D99_RS02560	ENOG4108V0P	LemA family
G8D99_RS02575	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G8D99_RS02585	ENOG4105BZU	Histidine kinase
G8D99_RS02590	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G8D99_RS02595	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G8D99_RS02645	ENOG4105C9M	aspartyl-trna synthetase
G8D99_RS02655	ENOG4105UGU	tonB-dependent Receptor
G8D99_RS02675	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
G8D99_RS02685	ENOG4105CSU	acyl-Coa dehydrogenase
G8D99_RS02690	ENOG4105CSU	acyl-Coa dehydrogenase
G8D99_RS02700	ENOG4105EB3	Histidine kinase
G8D99_RS02705	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G8D99_RS02710	ENOG4105C85	amino acid
G8D99_RS02720	ENOG4105MSB	protein, conserved in bacteria
G8D99_RS02730	ENOG4105CNG	UPF0061 protein
G8D99_RS02745	ENOG4108WBT	adenosyltransferase
G8D99_RS02770	ENOG4105TW1	Carbohydrate-selective porin OprB
G8D99_RS02775	ENOG4105DZG	Dehydrogenase
G8D99_RS02780	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
G8D99_RS02790	ENOG4105CHU	acetyl-coa acetyltransferase
G8D99_RS02810	ENOG4108IQI	permease
G8D99_RS02820	ENOG4105C2W	permease
G8D99_RS02825	ENOG4105CI3	gtp-binding protein typa
G8D99_RS02830	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G8D99_RS02845	ENOG4105TW1	Carbohydrate-selective porin OprB
G8D99_RS02855	ENOG4105TW1	Carbohydrate-selective porin OprB
G8D99_RS02860	ENOG4105CHB	tonB-dependent Receptor
G8D99_RS02865	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8D99_RS02885	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
G8D99_RS02890	ENOG410633P	Hydantoin racemase
G8D99_RS02910	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G8D99_RS02915	ENOG4108I0Z	Aconitate hydratase
G8D99_RS02945	ENOG4105BZU	Histidine kinase
G8D99_RS02950	ENOG4105D3G	Pseudouridine synthase
G8D99_RS02965	ENOG4105DSF	transport protein
G8D99_RS02970	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G8D99_RS02990	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G8D99_RS03010	ENOG4106KVJ	cytochrome C assembly protein
G8D99_RS03015	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G8D99_RS03020	ENOG4105MJ9	esterase
G8D99_RS03030	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G8D99_RS03040	ENOG4105HF0	Membrane
G8D99_RS03050	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G8D99_RS03060	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G8D99_RS03065	ENOG4105C94	Transporter
G8D99_RS03085	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
G8D99_RS03090	ENOG4108UWD	Iron-storage protein
G8D99_RS03095	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G8D99_RS03100	ENOG4105FE9	pseudouridine synthase
G8D99_RS03105	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G8D99_RS03110	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
G8D99_RS03115	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
G8D99_RS03120	ENOG4108BPE	-transporting atpase
G8D99_RS03125	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
G8D99_RS03130	ENOG4105VGS	50s ribosomal protein l32
G8D99_RS03145	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G8D99_RS03150	ENOG4105CHR	reductase
G8D99_RS03160	ENOG4109066	lysm domain bon superfamily protein
G8D99_RS03165	ENOG4108IGT	Dipeptidase
G8D99_RS03170	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
G8D99_RS03285	ENOG4105D06	uba thif-type nad fad binding protein
G8D99_RS03295	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G8D99_RS03300	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G8D99_RS03305	ENOG4107EXC	regulatoR
G8D99_RS03310	ENOG4105JJR	Histidine kinase
G8D99_RS03335	ENOG4105GKE	subunit e
G8D99_RS03340	ENOG4107QIZ	NADH dehydrogenase
G8D99_RS03345	ENOG4108IEH	NADH dehydrogenase subunit g
G8D99_RS03355	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8D99_RS03360	ENOG4107UFS	subunit j
G8D99_RS03365	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8D99_RS03370	ENOG4105D65	subunit l
G8D99_RS03375	ENOG4105C8S	subunit m
G8D99_RS03385	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G8D99_RS03405	ENOG4105DUM	transcriptional regulator, lysR family
G8D99_RS03410	ENOG4105DP0	ferredoxin-NADP reductase
G8D99_RS03440	ENOG4105CBX	hi0933 family
G8D99_RS03495	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G8D99_RS03525	ENOG4105D1F	ATP-binding protein
G8D99_RS03580	ENOG410624X	efflux transporter, rnd family, mfp subunit
G8D99_RS03590	ENOG4108UNF	response regulator
G8D99_RS03595	ENOG4105M3Z	response regulator
G8D99_RS03600	ENOG4108ZGA	chew protein
G8D99_RS03605	ENOG4105C8Q	Methyl-accepting chemotaxis
G8D99_RS03610	ENOG4105CBS	Chea signal transduction histidine kinase
G8D99_RS03625	ENOG4107PEH	Entericidin EcnA/B family
G8D99_RS03635	ENOG4105WD1	Membrane
G8D99_RS03695	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
G8D99_RS03705	ENOG4105EM2	membrane
G8D99_RS03710	ENOG4105C2C	drug resistance transporter, Bcr CflA
G8D99_RS03725	ENOG4105D6U	Sodium Glutamate Symporter
G8D99_RS03730	ENOG4105D78	K07001 NTE family protein
G8D99_RS03740	ENOG4108S4H	thioesterase Superfamily protein
G8D99_RS03755	ENOG4105CKI	cobalamin synthesis protein
G8D99_RS03760	ENOG4108VWS	Yaeq family
G8D99_RS03775	ENOG4107BJW	polysaccharide deacetylase
G8D99_RS03780	ENOG4105CND	Glycosyl transferase, family 2
G8D99_RS03840	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G8D99_RS03850	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G8D99_RS03860	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G8D99_RS03870	ENOG4108Z03	MAF-like protein
G8D99_RS03875	ENOG4105C03	ribonuclease
G8D99_RS03885	ENOG4105D8T	Acyltransferase
G8D99_RS03895	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
G8D99_RS03920	ENOG4105C85	amino acid
G8D99_RS03925	ENOG4105C7F	AcnD-accessory protein PrpF
G8D99_RS03930	ENOG4105BZU	Histidine kinase
G8D99_RS03935	ENOG4105CTB	Polyprenyl synthetase
G8D99_RS03940	ENOG4105CK7	Sodium proline symporter
G8D99_RS03955	ENOG4105D78	K07001 NTE family protein
G8D99_RS03990	ENOG4107VMU	Membrane
G8D99_RS04000	ENOG4105D4T	Citrate transporter
G8D99_RS04005	ENOG4105C37	(CBS) domain
G8D99_RS04015	ENOG4107RET	Isocitrate lyase
G8D99_RS04020	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
G8D99_RS04025	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
G8D99_RS04040	ENOG4107S78	Band 7 protein
G8D99_RS04055	ENOG4105CKW	Inner membrane protein yedI
G8D99_RS04060	ENOG4105CGZ	zinc metallopeptidase
G8D99_RS04125	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G8D99_RS04130	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G8D99_RS04145	ENOG4105HBR	Rna-binding protein
G8D99_RS04155	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G8D99_RS04160	ENOG4105EEI	dihydropteroate synthase
G8D99_RS04195	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G8D99_RS04250	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
G8D99_RS04255	ENOG4105BZS	acriflavin resistance protein
G8D99_RS04270	ENOG4105E4C	Lytic transglycosylase catalytic
G8D99_RS04275	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G8D99_RS04285	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
G8D99_RS04290	ENOG4108RRZ	Transcription elongation factor GreB
G8D99_RS04300	ENOG4105C2I	pirin domain protein
G8D99_RS04315	ENOG4105NX3	Membrane
G8D99_RS04335	ENOG4105BZU	Histidine kinase
G8D99_RS04345	ENOG4105EUJ	GTP cyclohydrolase i
G8D99_RS04380	ENOG4107QYG	anthranilate phosphoribosyltransferase
G8D99_RS04385	ENOG4105DDQ	anthranilate synthase
G8D99_RS04415	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
G8D99_RS04450	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8D99_RS04455	ENOG4107QNR	UPF0135 protein
G8D99_RS04460	ENOG4105C0H	protease
G8D99_RS04470	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G8D99_RS04480	ENOG4105BZG	amino acid carrier protein
G8D99_RS04485	ENOG4105C85	amino acid
G8D99_RS04495	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G8D99_RS04500	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G8D99_RS04510	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8D99_RS04520	ENOG4105EW9	transcriptional regulator AsnC family
G8D99_RS04525	ENOG4105N14	lysine exporter protein LysE YggA
G8D99_RS04530	ENOG4105BZJ	Electron transfer flavoprotein
G8D99_RS04535	ENOG4105C10	Electron transfer flavoprotein
G8D99_RS04545	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D99_RS04555	ENOG4105CK2	sodium dicarboxylate symporter
G8D99_RS04570	ENOG4107KET	secretion protein, HlyD family
G8D99_RS04600	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
G8D99_RS04605	ENOG4105EKE	dihydroorotase
G8D99_RS04625	ENOG4105DAA	L-lactate
G8D99_RS04630	ENOG41073TP	transcriptional regulator
G8D99_RS04640	ENOG4105CXG	d-lactate dehydrogenase
G8D99_RS04650	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8D99_RS04660	ENOG4105F1S	paraquat-inducible protein a
G8D99_RS04665	ENOG4105F1S	paraquat-inducible protein a
G8D99_RS04670	ENOG4105DY2	Paraquat-inducible protein b
G8D99_RS04685	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
G8D99_RS04695	ENOG4105C6K	Malic enzyme
G8D99_RS04700	ENOG4105BZU	Histidine kinase
G8D99_RS04705	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G8D99_RS04710	ENOG4105SYT	Methylenetetrahydrofolate reductase
G8D99_RS04715	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G8D99_RS04735	ENOG4107QPN	acyl-Coa dehydrogenase
G8D99_RS04740	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G8D99_RS04750	ENOG4105DSW	Fusaric acid resistance protein
G8D99_RS04755	ENOG4105DSW	Fusaric acid resistance protein
G8D99_RS04760	ENOG4105EUB	pirin domain protein
G8D99_RS04765	ENOG4105EJC	lysr family transcriptional regulator
G8D99_RS04775	ENOG4105C57	major facilitator superfamily
G8D99_RS04785	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G8D99_RS04790	ENOG4105CE9	30S ribosomal protein S2
G8D99_RS04815	ENOG4105CVE	Lytic murein transglycosylase
G8D99_RS04820	ENOG4105CNI	cell division protein FtsW
G8D99_RS04835	ENOG4105E3A	(ABC) transporter
G8D99_RS04840	ENOG4105DA5	(ABC) transporter
G8D99_RS04850	ENOG4105C85	amino acid
G8D99_RS04885	ENOG4105NXH	GreA GreB family elongation factor
G8D99_RS04920	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G8D99_RS04925	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G8D99_RS04935	ENOG4105M8F	Biopolymer transport protein exbD tolR
G8D99_RS04940	ENOG4105E02	MotA TolQ exbB proton channel
G8D99_RS04945	ENOG4107YD3	Thioesterase
G8D99_RS04960	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G8D99_RS04975	ENOG4105ERU	peptidase
G8D99_RS04985	ENOG4107QTF	adenylosuccinate lyase
G8D99_RS04995	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G8D99_RS05015	ENOG4108Z0R	Transferase
G8D99_RS05020	ENOG4105DZ1	carboxypeptidase
G8D99_RS05040	ENOG4108K5P	(LipO)protein
G8D99_RS05045	ENOG4105JQN	Transcriptional regulator
G8D99_RS05050	ENOG4105C8Y	Acetylornithine aminotransferase
G8D99_RS05055	ENOG4105M2J	Glutaredoxin
G8D99_RS05060	ENOG4105DAN	ATP-dependent protease
G8D99_RS05075	ENOG4105DHU	Bile acid
G8D99_RS05095	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
G8D99_RS05100	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G8D99_RS05105	ENOG4105D22	carbon starvation protein
G8D99_RS05120	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G8D99_RS05130	ENOG4105F8C	transglutaminase domain-containing protein
G8D99_RS05140	ENOG4105E9K	Isocitrate dehydrogenase
G8D99_RS05160	ENOG4105DDY	UPF0142 protein ycaO
G8D99_RS05165	ENOG4105C7N	Xanthine uracil vitamin C permease
G8D99_RS05170	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
G8D99_RS05180	ENOG4105CPW	cytochrome b561
G8D99_RS05190	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G8D99_RS05200	ENOG4105CFH	Aspartokinase
G8D99_RS05205	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G8D99_RS05210	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G8D99_RS05225	ENOG4108UMN	azlc family
G8D99_RS05230	ENOG4105EW9	transcriptional regulator AsnC family
G8D99_RS05240	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G8D99_RS05245	ENOG4105ERG	peptidase m48, ste24p
G8D99_RS05260	ENOG4105CPC	Aldo Keto reductase
G8D99_RS05265	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
G8D99_RS05270	ENOG4108UKZ	OsmC family
G8D99_RS05280	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
G8D99_RS05285	ENOG4105D7W	serine acetyltransferase
G8D99_RS05290	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8D99_RS05310	ENOG4105CXT	aspartate transcarbamylase
G8D99_RS05315	ENOG4105CD3	dihydroorotase
G8D99_RS05320	ENOG4108ZG0	Ompa motb domain protein
G8D99_RS05335	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G8D99_RS05340	ENOG4105CHH	sulfate transporter
G8D99_RS05345	ENOG4108K3A	Glutathione S-transferase
G8D99_RS05360	ENOG4105M08	Membrane
G8D99_RS05365	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8D99_RS05380	ENOG4105C1J	atp-dependent rna helicase
G8D99_RS05390	ENOG41069NU	Nitroreductase
G8D99_RS05415	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G8D99_RS05425	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G8D99_RS05440	ENOG4105C5I	Dehydrogenase
G8D99_RS05445	ENOG4105ERG	peptidase m48, ste24p
G8D99_RS05460	ENOG4105KTH	gatB Yqey
G8D99_RS05560	ENOG4108UMI	ABC transporter, permease
G8D99_RS05565	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G8D99_RS05570	ENOG4105D01	(LipO)protein
G8D99_RS05575	ENOG4105D01	(LipO)protein
G8D99_RS05600	ENOG4105C12	Phosphoribosylglycinamide synthetase
G8D99_RS05605	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G8D99_RS05610	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
G8D99_RS05665	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G8D99_RS05670	ENOG4105CDU	Replicative dna helicase
G8D99_RS05680	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G8D99_RS05695	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
G8D99_RS05700	ENOG4105CCU	oxidase (Subunit III)
G8D99_RS05705	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G8D99_RS05710	ENOG4105E2S	oxidase) subunit II
G8D99_RS05740	ENOG4105CND	Glycosyl transferase, family 2
G8D99_RS05760	ENOG4108Z12	YiaAB two helix domain-containing protein
G8D99_RS05765	ENOG4105DEN	Luciferase family
G8D99_RS05785	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G8D99_RS05790	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G8D99_RS05800	ENOG4105D06	uba thif-type nad fad binding protein
G8D99_RS05830	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
G8D99_RS05835	ENOG4105CFU	surface antigen
G8D99_RS05860	ENOG4107QIJ	Aconitate hydratase 2
G8D99_RS05885	ENOG4105EW9	transcriptional regulator AsnC family
G8D99_RS05890	ENOG4105EYW	Ion transport protein
G8D99_RS05895	ENOG4105D6U	Sodium Glutamate Symporter
G8D99_RS05900	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
G8D99_RS05905	ENOG4105DZ2	Transcriptional regulator
G8D99_RS05910	ENOG4105CUY	Mechanosensitive ion channel
G8D99_RS05915	ENOG4108VMM	UPF0756 membrane protein
G8D99_RS05920	ENOG4105I08	Pseudouridine synthase
G8D99_RS05940	ENOG4105K8N	protein family UPF0079, ATPase
G8D99_RS05945	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G8D99_RS05950	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G8D99_RS05955	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G8D99_RS05960	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G8D99_RS05965	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G8D99_RS05970	ENOG4105EHM	Aminoglycoside phosphotransferase
G8D99_RS05975	ENOG4108S0S	Nucleotidyl transferase
G8D99_RS05985	ENOG4107QJE	Chromosome Partitioning Protein
G8D99_RS05990	ENOG4105FA0	parb-like partition protein
G8D99_RS06005	ENOG4105BZ1	(ABC) transporter
G8D99_RS06010	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G8D99_RS06020	ENOG4107QRG	dna polymerase iii
G8D99_RS06030	ENOG4105F8V	Hydrolase, tatD family
G8D99_RS06040	ENOG4108VAU	general secretion pathway protein G
G8D99_RS06055	ENOG4108RTD	type II secretion system protein K
G8D99_RS06065	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G8D99_RS06075	ENOG4108Z6B	deaminase
G8D99_RS06090	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G8D99_RS06095	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G8D99_RS06130	ENOG4105ZED	uncharacterized protein ygaH
G8D99_RS06135	ENOG4108UMN	azlc family
G8D99_RS06145	ENOG4105C3G	gtp-binding protein
G8D99_RS06150	ENOG4108UMI	ABC transporter, permease
G8D99_RS06155	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G8D99_RS06160	ENOG4105D01	(LipO)protein
G8D99_RS06175	ENOG4107T8P	acyl-Coa dehydrogenase
G8D99_RS06180	ENOG4108RXX	maleylacetoacetate isomerase
G8D99_RS06200	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
G8D99_RS06260	ENOG4107IIZ	CRISPR-associated helicase, Cas3
G8D99_RS06280	ENOG41067CV	Integrase
G8D99_RS06425	ENOG4107QI6	Cysteine desulfurase
G8D99_RS06440	ENOG4105CNU	cell division protein FtsK
G8D99_RS06450	ENOG4105D01	(LipO)protein
G8D99_RS06455	ENOG4108UMI	ABC transporter, permease
G8D99_RS06485	ENOG4107T8P	acyl-Coa dehydrogenase
G8D99_RS06490	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G8D99_RS06495	ENOG4108UMI	ABC transporter, permease
G8D99_RS06500	ENOG4105D01	(LipO)protein
G8D99_RS06510	ENOG4105C54	Major Facilitator superfamily
G8D99_RS06540	ENOG4106NZI	LysR family Transcriptional regulator
G8D99_RS06545	ENOG4105C26	Dehydrogenase
G8D99_RS06550	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8D99_RS06560	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS06565	ENOG4105E39	Enoyl-CoA hydratase
G8D99_RS06575	ENOG4105CSH	Transporter
G8D99_RS06590	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G8D99_RS06595	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G8D99_RS06600	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
G8D99_RS06615	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
G8D99_RS06630	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G8D99_RS06640	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G8D99_RS06655	ENOG4108YYC	ycei family
G8D99_RS06660	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
G8D99_RS06665	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G8D99_RS06670	ENOG4107GJV	short-chain dehydrogenase reductase
G8D99_RS06680	ENOG4105DQ4	alcohol dehydrogenase
G8D99_RS06690	ENOG4105CPD	ethanolamine ammonia-lyase
G8D99_RS06695	ENOG4107R55	ethanolamine transporter
G8D99_RS06705	ENOG4107RR1	TRANSCRIPTIONal
G8D99_RS06725	ENOG4107QUV	Domain protein
G8D99_RS06750	ENOG4105CD8	aminopeptidase N
G8D99_RS06765	ENOG4105EW9	transcriptional regulator AsnC family
G8D99_RS06770	ENOG4105CK7	Sodium proline symporter
G8D99_RS06775	ENOG4108IJ0	Aspartate ammonia-lyase
G8D99_RS06785	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G8D99_RS06790	ENOG4108MXF	Alpha Beta Hydrolase
G8D99_RS06800	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8D99_RS06835	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G8D99_RS06840	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G8D99_RS06880	ENOG4108RCM	Nitroreductase
G8D99_RS06925	ENOG4105CR8	Transcriptional regulator
G8D99_RS06930	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G8D99_RS06940	ENOG4105CZN	Potassium uptake protein
G8D99_RS06945	ENOG4107ZYR	domain protein
G8D99_RS06955	ENOG4105C7B	Threonine dehydratase
G8D99_RS06960	ENOG4105E66	phosphoriboisomerase A
G8D99_RS06995	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G8D99_RS07000	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8D99_RS07025	ENOG4105CR4	methylisocitrate lyase
G8D99_RS07030	ENOG4105BZN	citrate synthase
G8D99_RS07040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D99_RS07045	ENOG4105CUX	Signal transduction histidine kinase
G8D99_RS07055	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G8D99_RS07065	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G8D99_RS07070	ENOG4105KNE	Phosphatidate cytidylyltransferase
G8D99_RS07080	ENOG4105DZP	Membrane-associated zinc metalloprotease
G8D99_RS07085	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8D99_RS07105	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8D99_RS07120	ENOG4105Y3E	Modulates RecA activity (By similarity)
G8D99_RS07125	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G8D99_RS07130	ENOG4105VEJ	Heat shock protein
G8D99_RS07135	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
G8D99_RS07140	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
G8D99_RS07150	ENOG4105CSH	Transporter
G8D99_RS07160	ENOG4105K4T	epimerase
G8D99_RS07165	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
G8D99_RS07180	ENOG4108JA2	transcriptioN-repair coupling factor
G8D99_RS07190	ENOG4105F8J	Adenylate Guanylate cyclase
G8D99_RS07195	ENOG4108ZIT	Ferredoxin, 2FE-2S
G8D99_RS07210	ENOG4108Z4V	iron-sulfur cluster assembly
G8D99_RS07215	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
G8D99_RS07225	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
G8D99_RS07240	ENOG4105K70	DNA-binding protein
G8D99_RS07250	ENOG4105E7U	AraC family transcriptional regulator
G8D99_RS07265	ENOG4108MJ3	acetyltransferase
G8D99_RS07270	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS07275	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS07290	ENOG4105VEQ	Cold shock protein
G8D99_RS07295	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
G8D99_RS07355	ENOG4105BZU	Histidine kinase
G8D99_RS07365	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G8D99_RS07370	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G8D99_RS07380	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G8D99_RS07400	ENOG4105CS6	Rhs element vgr protein
G8D99_RS07470	ENOG4105CNA	YD repeat protein
G8D99_RS07495	ENOG4105CNA	YD repeat protein
G8D99_RS07535	ENOG4105CNA	YD repeat protein
G8D99_RS07585	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
G8D99_RS07590	ENOG4105CMR	udp-glucose 4-epimerase
G8D99_RS07605	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
G8D99_RS07620	ENOG4105CZM	Major Facilitator
G8D99_RS07635	ENOG4105KK6	nuclease
G8D99_RS07640	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS07680	ENOG4107RZC	phospholipase d
G8D99_RS07690	ENOG4105CGF	Aromatic amino acid aminotransferase
G8D99_RS07695	ENOG4105EV9	Alpha Beta Hydrolase
G8D99_RS07700	ENOG4105BZU	Histidine kinase
G8D99_RS07705	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G8D99_RS07710	ENOG4105CZX	twitching motility protein
G8D99_RS07720	ENOG4108R6W	Transcriptional regulator, ARAC family
G8D99_RS07730	ENOG4105BZ1	(ABC) transporter
G8D99_RS07775	ENOG4105CS6	Rhs element vgr protein
G8D99_RS07795	ENOG4105CNA	YD repeat protein
G8D99_RS07805	ENOG4105CNA	YD repeat protein
G8D99_RS07845	ENOG4105CNA	YD repeat protein
G8D99_RS07885	ENOG4105CNA	YD repeat protein
G8D99_RS07935	ENOG4105DDW	LysR family Transcriptional regulator
G8D99_RS07945	ENOG4105EXW	epimerase dehydratase
G8D99_RS07955	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8D99_RS07970	ENOG4105WAB	arsR family transcriptional regulator
G8D99_RS07980	ENOG4105C94	Transporter
G8D99_RS07985	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
G8D99_RS08010	ENOG4105CC0	LysR family Transcriptional regulator
G8D99_RS08025	ENOG41080HT	Transcriptional regulator, arsr family
G8D99_RS08050	ENOG4105GR3	Histidine kinase
G8D99_RS08065	ENOG4105VT2	5-hydroxyisourate hydrolase
G8D99_RS08085	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
G8D99_RS08125	ENOG4105CZJ	Aldehyde dehydrogenase
G8D99_RS08145	ENOG4107EJG	GntR family transcriptional regulator
G8D99_RS08150	ENOG4105C5I	Dehydrogenase
G8D99_RS08160	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G8D99_RS08165	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G8D99_RS08170	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D99_RS08175	ENOG4105CSU	acyl-Coa dehydrogenase
G8D99_RS08185	ENOG4105CHU	acetyl-coa acetyltransferase
G8D99_RS08190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8D99_RS08200	ENOG4107RGD	Major Facilitator superfamily
G8D99_RS08215	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8D99_RS08240	ENOG4105MRR	Transcriptional regulator (By similarity)
G8D99_RS08255	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G8D99_RS08270	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
G8D99_RS08275	ENOG4105E0C	molybdate abc transporter
G8D99_RS08280	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
G8D99_RS08285	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G8D99_RS08290	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G8D99_RS08295	ENOG4108ZAF	Molybdopterin
G8D99_RS08320	ENOG4108IFG	nitrite reductase, (NAD(P)H)
G8D99_RS08325	ENOG4107QZF	nitrite reductase NADPH large subunit
G8D99_RS08330	ENOG4107RNU	major facilitator superfamily MFS_1
G8D99_RS08335	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G8D99_RS08355	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D99_RS08360	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS08365	ENOG4108IPT	Naphthoate synthase
G8D99_RS08375	ENOG4108SY4	MarR family Transcriptional regulator
G8D99_RS08380	ENOG4107RGD	Major Facilitator superfamily
G8D99_RS08385	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G8D99_RS08390	ENOG4105EQ0	Major Facilitator superfamily
G8D99_RS08395	ENOG4107QNJ	CoA-transferase subunit B
G8D99_RS08405	ENOG4107RGD	Major Facilitator superfamily
G8D99_RS08410	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS08415	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS08430	ENOG4105D2S	major facilitator superfamily
G8D99_RS08435	ENOG41090HR	transcriptional regulator
G8D99_RS08440	ENOG4108KB2	LysR family Transcriptional regulator
G8D99_RS08445	ENOG4105DTQ	mandelate racemase muconate lactonizing
G8D99_RS08450	ENOG4105NN7	muconolactone delta-isomerase
G8D99_RS08460	ENOG4105FUY	alpha subunit
G8D99_RS08465	ENOG4108UKV	benzoate 1,2-dioxygenase
G8D99_RS08470	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
G8D99_RS08475	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
G8D99_RS08480	ENOG4105DKK	Benzoate
G8D99_RS08485	ENOG4107QP7	CoA-transferase subunit A
G8D99_RS08490	ENOG4107QNJ	CoA-transferase subunit B
G8D99_RS08495	ENOG4105F2Z	3-oxoadipate enol-lactonase
G8D99_RS08505	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G8D99_RS08510	ENOG4105CHU	acetyl-coa acetyltransferase
G8D99_RS08515	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8D99_RS08520	ENOG4105E39	Enoyl-CoA hydratase
G8D99_RS08525	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS08530	ENOG4107RGD	Major Facilitator superfamily
G8D99_RS08535	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G8D99_RS08550	ENOG4105GVF	(ABC) transporter
G8D99_RS08560	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
G8D99_RS08565	ENOG4106UW1	Major Facilitator superfamily
G8D99_RS08595	ENOG4105QNF	Outer membrane lipoprotein
G8D99_RS08605	ENOG4105DIJ	Phosphoethanolamine transferase
G8D99_RS08610	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8D99_RS08615	ENOG4105DHQ	Histidine kinase
G8D99_RS08645	ENOG4105H3G	oxidoreductase
G8D99_RS08650	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D99_RS08655	ENOG4105CYC	Transferase
G8D99_RS08660	ENOG4105CHU	acetyl-coa acetyltransferase
G8D99_RS08665	ENOG4105CSU	acyl-Coa dehydrogenase
G8D99_RS08670	ENOG41062JF	Transcriptional regulator
G8D99_RS08675	ENOG4105C6T	cysteine synthase
G8D99_RS08690	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D99_RS08695	ENOG4105R8C	Transcriptional regulator
G8D99_RS08700	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS08705	ENOG4107QX3	carboxylase
G8D99_RS08710	ENOG4105E39	Enoyl-CoA hydratase
G8D99_RS08730	ENOG4107QNJ	CoA-transferase subunit B
G8D99_RS08735	ENOG4105CRW	Short chain fatty acid transporter
G8D99_RS08750	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
G8D99_RS08755	ENOG4105HDD	phospholipase
G8D99_RS08765	ENOG41082BV	acetyltransferase
G8D99_RS08780	ENOG4105PV3	Inner membrane protein yqiJ
G8D99_RS08800	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G8D99_RS08805	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G8D99_RS08840	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
G8D99_RS08875	ENOG41080XP	Cbs domain
G8D99_RS08880	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G8D99_RS08910	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G8D99_RS08920	ENOG4105C28	cystathionine
G8D99_RS08940	ENOG4105K59	histidine triad (HIT) protein
G8D99_RS08960	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G8D99_RS08965	ENOG4108YZT	Adenosylcobinamide kinase
G8D99_RS08985	ENOG4105EYM	Major Facilitator superfamily
G8D99_RS09015	ENOG4108Z66	YbaK ebsC protein
G8D99_RS09020	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
G8D99_RS09025	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
G8D99_RS09030	ENOG41077RS	Phosphatase
G8D99_RS09045	ENOG4108HPI	phosphatidate Cytidylyltransferase
G8D99_RS09055	ENOG4105D2S	major facilitator superfamily
G8D99_RS09105	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8D99_RS09115	ENOG4107TSN	permease
G8D99_RS09120	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G8D99_RS09140	ENOG4108TZV	Membrane
G8D99_RS09145	ENOG4105D2N	Aldolase
G8D99_RS09155	ENOG4105BZA	Phosphoglycerate kinase
G8D99_RS09165	ENOG4108UHJ	MAF-like protein
G8D99_RS09235	ENOG4105EZE	Cupin 4 family protein
G8D99_RS09240	ENOG4105CBC	glutamate synthase
G8D99_RS09265	ENOG4105C0A	alcohol dehydrogenase
G8D99_RS09275	ENOG4107QMP	dna polymerase iii subunits gamma and tau
G8D99_RS09290	ENOG4105CHR	reductase
G8D99_RS09295	ENOG4105CHU	acetyl-coa acetyltransferase
G8D99_RS09310	ENOG4105DUM	transcriptional regulator, lysR family
G8D99_RS09315	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G8D99_RS09320	ENOG4108NIW	Leucine export protein LeuE
G8D99_RS09325	ENOG4105DKK	Benzoate
G8D99_RS09330	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G8D99_RS09335	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
G8D99_RS09355	ENOG4105EE5	Membrane protein terC
G8D99_RS09380	ENOG4107QP3	malate synthase g
G8D99_RS09385	ENOG4105D6Z	AFG1 family ATPase
G8D99_RS09390	ENOG4107RN6	Monooxygenase
G8D99_RS09395	ENOG4105DWU	Membrane
G8D99_RS09405	ENOG4108V06	Glutathione peroxidase
G8D99_RS09410	ENOG4105E0X	reductase
G8D99_RS09415	ENOG4105CHM	Aminotransferase
G8D99_RS09420	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G8D99_RS09440	ENOG4105C0B	DNA polymerase III (alpha subunit)
G8D99_RS09475	ENOG4108Z4U	Ferredoxin
G8D99_RS09500	ENOG4108KSA	LysR family transcriptional regulator
G8D99_RS09520	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
G8D99_RS09525	ENOG4105BZ1	(ABC) transporter
G8D99_RS09535	ENOG4108IUZ	ABC transporter
G8D99_RS09540	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
G8D99_RS09555	ENOG4105C2X	Arabinose 5-phosphate isomerase
G8D99_RS09675	ENOG4105CHR	reductase
G8D99_RS09680	ENOG4105EUB	pirin domain protein
G8D99_RS09695	ENOG4105CQ7	ATP-dependent helicase
G8D99_RS09700	ENOG4105D3R	alkyl hydroperoxide reductase
G8D99_RS09725	ENOG4108JU3	Alkyl hydroperoxide reductase
G8D99_RS09735	ENOG4105CK2	sodium dicarboxylate symporter
G8D99_RS09755	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G8D99_RS09770	ENOG4105MUA	Resistance protein
G8D99_RS09810	ENOG4105DAX	Pfam:DUF2983
G8D99_RS09845	ENOG4108M24	von Willebrand factor, type A
G8D99_RS09850	ENOG4107QS8	(LipO)protein
G8D99_RS09865	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G8D99_RS09895	ENOG4105KVH	Transcriptional regulator
G8D99_RS09900	ENOG4105ECR	NmrA family
G8D99_RS09935	ENOG4105QNF	Outer membrane lipoprotein
G8D99_RS09940	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G8D99_RS09950	ENOG4105BZU	Histidine kinase
G8D99_RS09955	ENOG4105BZU	Histidine kinase
G8D99_RS09995	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
G8D99_RS10000	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
G8D99_RS10005	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
G8D99_RS10015	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G8D99_RS10030	ENOG4105C3F	Signal peptidase i
G8D99_RS10045	ENOG4105C0H	protease
G8D99_RS10050	ENOG4108IYU	L-aspartate oxidase
G8D99_RS10065	ENOG4105HHA	aminodeoxychorismate lyase
G8D99_RS10075	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G8D99_RS10085	ENOG4108I5D	sulfate abc transporter
G8D99_RS10090	ENOG4105ECW	sulfate abc transporter
G8D99_RS10095	ENOG4108IJ6	ABC transporter
G8D99_RS10100	ENOG4107R11	Transcriptional regulator
G8D99_RS10115	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G8D99_RS10125	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
G8D99_RS10135	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8D99_RS10145	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
G8D99_RS10155	ENOG4108IPT	Naphthoate synthase
G8D99_RS10165	ENOG4105EGD	dinuclear metal center protein, YbgI family
G8D99_RS10175	ENOG4108ETH	Formylglycinamide ribotide synthetase
G8D99_RS10185	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
G8D99_RS10190	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G8D99_RS10210	ENOG4105DY8	decarboxylase
G8D99_RS10215	ENOG4108JPW	Aminotransferase
G8D99_RS10240	ENOG4105EJ2	Transcriptional regulator
G8D99_RS10245	ENOG4108IQE	Amp-dependent synthetase and ligase
G8D99_RS10250	ENOG4105C0A	alcohol dehydrogenase
G8D99_RS10275	ENOG4105C09	Bile acid
G8D99_RS10280	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
G8D99_RS10285	ENOG4105D3G	Pseudouridine synthase
G8D99_RS10305	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G8D99_RS10315	ENOG4105I7R	Adenylate cyclase
G8D99_RS10325	ENOG4108IND	Tetr family transcriptional regulator
G8D99_RS10330	ENOG4107RTG	Major Facilitator superfamily
G8D99_RS10355	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G8D99_RS10375	ENOG4108R99	pseudouridine synthase
G8D99_RS10385	ENOG4105DZC	cytosine deaminase
G8D99_RS10395	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
G8D99_RS10405	ENOG4105DZ1	carboxypeptidase
G8D99_RS10410	ENOG4105CEP	NADH dehydrogenase
G8D99_RS10415	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G8D99_RS10420	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G8D99_RS10450	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G8D99_RS10455	ENOG4105CQC	Prephenate dehydratase
G8D99_RS10465	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS10470	ENOG4107QYG	anthranilate phosphoribosyltransferase
G8D99_RS10475	ENOG4105VUT	cytoplasmic protein
G8D99_RS10480	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G8D99_RS10485	ENOG4105BZ4	penicillin-binding protein
G8D99_RS10495	ENOG4105M6F	mutator MutT protein
G8D99_RS10505	ENOG4105DHQ	Histidine kinase
G8D99_RS10510	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8D99_RS10520	ENOG4105WXI	Bacterial OB fold (BOF) protein
G8D99_RS10525	ENOG4107QHF	type ii secretion system protein e
G8D99_RS10540	ENOG4108R96	Methyltransferase, YaeB family
G8D99_RS10545	ENOG4105DP0	ferredoxin-NADP reductase
G8D99_RS10550	ENOG4105CAU	Arsenical resistance protein, ArsH
G8D99_RS10555	ENOG4105D6J	arsenicaL-resistance protein
G8D99_RS10560	ENOG4107WAU	Protein tyrosine phosphatase
G8D99_RS10565	ENOG41082YX	Transcriptional regulator, arsr family
G8D99_RS10575	ENOG4108JU3	Alkyl hydroperoxide reductase
G8D99_RS10615	ENOG4105C02	permease
G8D99_RS10620	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G8D99_RS10625	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G8D99_RS10645	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
G8D99_RS10650	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G8D99_RS10655	ENOG4105D60	lipoprotein releasing system transmembrane protein
G8D99_RS10670	ENOG4108UPT	UPF0178 protein
G8D99_RS10675	ENOG4108IQI	permease
G8D99_RS10690	ENOG4108IQI	permease
G8D99_RS10710	ENOG4107S01	Repressor protein MetJ
G8D99_RS10720	ENOG4108JQ5	ABC transporter
G8D99_RS10725	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
G8D99_RS10730	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
G8D99_RS10735	ENOG4105E43	Extracellular solute-binding protein, family 5
G8D99_RS10740	ENOG4105E9H	Lytic Murein transglycosylase
G8D99_RS10745	ENOG4107RZZ	dna polymerase iii epsilon subunit
G8D99_RS10755	ENOG4105E09	nadh pyrophosphatase
G8D99_RS10765	ENOG4105W4M	Transport-associated protein
G8D99_RS10780	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G8D99_RS10790	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
G8D99_RS10795	ENOG4105D0A	hydroxylase
G8D99_RS10800	ENOG4105BZU	Histidine kinase
G8D99_RS10805	ENOG4107RAQ	aminopeptidase
G8D99_RS10810	ENOG4105E07	UPF0149 protein
G8D99_RS10855	ENOG41079YP	Citrate utilization protein b
G8D99_RS10860	ENOG4107EFR	Flavocytochrome c
G8D99_RS10865	ENOG4106P55	Transcriptional regulator
G8D99_RS10870	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
G8D99_RS10875	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
G8D99_RS10900	ENOG4107QF7	multi-drug
G8D99_RS10915	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G8D99_RS10925	ENOG4107VAM	peptidase, m28
G8D99_RS10930	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G8D99_RS10935	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
G8D99_RS10945	ENOG4105D82	Glutamate dehydrogenase
G8D99_RS10950	ENOG4108R3D	Electron transport complex
G8D99_RS10955	ENOG4105CSM	endonuclease III
G8D99_RS10980	ENOG4105CJN	penicillin-binding protein
G8D99_RS10985	ENOG4106H78	methyltransferase
G8D99_RS11015	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
G8D99_RS11025	ENOG4107QN2	dihydrolipoyl dehydrogenase
G8D99_RS11030	ENOG4105C7S	Dehydrogenase
G8D99_RS11035	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
G8D99_RS11040	ENOG4105E33	succinate dehydrogenase
G8D99_RS11050	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
G8D99_RS11055	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
G8D99_RS11065	ENOG4105F95	Monooxygenase
G8D99_RS11085	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
G8D99_RS11090	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
G8D99_RS11100	ENOG4105C4K	Nad synthetase
G8D99_RS11130	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G8D99_RS11140	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G8D99_RS11160	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G8D99_RS11165	ENOG4105C34	Pseudouridine synthase
G8D99_RS11170	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8D99_RS11175	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G8D99_RS11190	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
G8D99_RS11220	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G8D99_RS11225	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G8D99_RS11270	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8D99_RS11280	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G8D99_RS11295	ENOG4105CUB	amino acid
G8D99_RS11305	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G8D99_RS11310	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G8D99_RS11335	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G8D99_RS11350	ENOG410841Q	phosphoesterase PA-phosphatase related protein
G8D99_RS11355	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G8D99_RS11360	ENOG4105BZS	acriflavin resistance protein
G8D99_RS11365	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8D99_RS11370	ENOG4105K8R	UPF0145 protein
G8D99_RS11375	ENOG41083A2	UPF0145 protein
G8D99_RS11380	ENOG4105CHR	reductase
G8D99_RS11390	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G8D99_RS11400	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
G8D99_RS11420	ENOG4105BZU	Histidine kinase
G8D99_RS11445	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
G8D99_RS11455	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
G8D99_RS11460	ENOG4108IY8	ABC, transporter
G8D99_RS11465	ENOG4106FTQ	Taurine ABC transporter, periplasmic
G8D99_RS11470	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
G8D99_RS11475	ENOG4105C11	sulfate adenylyltransferase), subunit 2
G8D99_RS11485	ENOG4108MRJ	
G8D99_RS11500	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G8D99_RS11505	ENOG4105VCQ	rubredoxin
G8D99_RS11510	ENOG4107QZF	nitrite reductase NADPH large subunit
G8D99_RS11520	ENOG4105C5Q	Transcriptional regulator
G8D99_RS11535	ENOG4107U91	Rhomboid family
G8D99_RS11540	ENOG4105CV6	ABC transporter, permease
G8D99_RS11545	ENOG4108I0Y	(ABC) transporter
G8D99_RS11550	ENOG4108UJV	acyl-CoA thioesterase i
G8D99_RS11555	ENOG4108V9Q	carbonic anhydrase
G8D99_RS11575	ENOG4105D05	Receptor
G8D99_RS11600	ENOG4105CJ3	phosphate transporter
G8D99_RS11605	ENOG4105C3R	Methionine synthase
G8D99_RS11615	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
G8D99_RS11620	ENOG4105CMT	Dihydroxyacetone kinase
G8D99_RS11635	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G8D99_RS11645	ENOG4105BZU	Histidine kinase
G8D99_RS11670	ENOG4105E9F	Enoyl-CoA hydratase
G8D99_RS11725	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
G8D99_RS11730	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G8D99_RS11735	ENOG4105CW7	secretion protein, HlyD family
G8D99_RS11740	ENOG4108VUY	thioesterase Superfamily protein
G8D99_RS11745	ENOG4105D52	delta-aminolevulinic acid dehydratase
G8D99_RS11750	ENOG4108DN8	FAD dependent oxidoreductase
G8D99_RS11765	ENOG4107RH8	nuclease SbcCD subunit D
G8D99_RS11770	ENOG4105EYH	Exonuclease
G8D99_RS11780	ENOG4105DFA	alanine racemase domain protein
G8D99_RS11785	ENOG4105CZX	twitching motility protein
G8D99_RS11790	ENOG4105CZX	twitching motility protein
G8D99_RS11795	ENOG41090R7	Ferric uptake
G8D99_RS11805	ENOG4105VDB	UPF0125 protein
G8D99_RS11820	ENOG4105E7A	Glutamine amidotransferase
G8D99_RS11830	ENOG4107QKV	phosphomannomutase
G8D99_RS11835	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G8D99_RS11840	ENOG4105C4R	Atp-dependent dna helicase
G8D99_RS11845	ENOG4108ZG0	Ompa motb domain protein
G8D99_RS11850	ENOG4108ZG0	Ompa motb domain protein
G8D99_RS11855	ENOG4106HNH	Acyl-transferase
G8D99_RS11865	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
G8D99_RS11870	ENOG4107QMS	site-determining protein
G8D99_RS11890	ENOG4105CNU	cell division protein FtsK
G8D99_RS11895	ENOG4105C3M	thioredoxin reductase
G8D99_RS11905	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
G8D99_RS11915	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
G8D99_RS11940	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G8D99_RS11955	ENOG4108YXA	Membrane
G8D99_RS11965	ENOG4105EW9	transcriptional regulator AsnC family
G8D99_RS11970	ENOG4107XGZ	Hydrolase
G8D99_RS11975	ENOG4105DWF	phosphomethylpyrimidine kinase
G8D99_RS11985	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G8D99_RS11995	ENOG4105KPY	Small multidrug resistance protein
G8D99_RS12005	ENOG4105E3B	Multicopper oxidase
G8D99_RS12015	ENOG4105DJV	ribulose-phosphate 3-epimerase
G8D99_RS12030	ENOG4108M3P	Membrane
G8D99_RS12050	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G8D99_RS12055	ENOG41072GX	Peptidase M22 Glycoprotease
G8D99_RS12060	ENOG4108Z0R	Transferase
G8D99_RS12065	ENOG4105P8F	nudix hydrolase
G8D99_RS12115	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G8D99_RS12120	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G8D99_RS12150	ENOG4105EAD	ABC transporter
G8D99_RS12155	ENOG4105DRP	amino acid AbC transporter
G8D99_RS12160	ENOG4105CDA	abc transporter atp-binding protein
G8D99_RS12200	ENOG4108KHX	Diguanylate cyclase
G8D99_RS12230	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
G8D99_RS12235	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G8D99_RS12250	ENOG4105D3R	alkyl hydroperoxide reductase
G8D99_RS12270	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G8D99_RS12290	ENOG4108ZX5	transcriptional regulator
G8D99_RS12315	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G8D99_RS12320	ENOG4108R6W	Transcriptional regulator, ARAC family
G8D99_RS12330	ENOG4105CHU	acetyl-coa acetyltransferase
G8D99_RS12335	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8D99_RS12355	ENOG4108UT2	hemolysin iii
G8D99_RS12360	ENOG4105CSH	Transporter
G8D99_RS12365	ENOG4105DIN	metallophosphoesterase
G8D99_RS12370	ENOG4107RZC	phospholipase d
G8D99_RS12385	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G8D99_RS12395	ENOG41067MG	lrgb family
G8D99_RS12410	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
G8D99_RS12415	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G8D99_RS12420	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G8D99_RS12425	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G8D99_RS12430	ENOG4108UJD	30S ribosomal protein S9
G8D99_RS12440	ENOG4105KB2	stringent starvation protein b
G8D99_RS12460	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS12465	ENOG4107QX3	carboxylase
G8D99_RS12480	ENOG4108RZE	Tetr family transcriptional regulator
G8D99_RS12490	ENOG4105C1G	acyl-Coa dehydrogenase
G8D99_RS12520	ENOG410903C	(LipO)protein
G8D99_RS12540	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G8D99_RS12555	ENOG4107QHF	type ii secretion system protein e
G8D99_RS12575	ENOG4105C2M	dna polymerase I
G8D99_RS12580	ENOG4108VIA	integral membrane protein
G8D99_RS12585	ENOG4105II7	pyrroline-5-carboxylate reductase
G8D99_RS12590	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G8D99_RS12600	ENOG4105C9X	ppx gppa phosphatase
G8D99_RS12610	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G8D99_RS12620	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G8D99_RS12625	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G8D99_RS12630	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G8D99_RS12675	ENOG4105CYM	Glutathione S-transferase
G8D99_RS12685	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G8D99_RS12695	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D99_RS12705	ENOG4105N42	UPF0307 protein
G8D99_RS12715	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G8D99_RS12720	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G8D99_RS12730	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G8D99_RS12735	ENOG4105DJ0	Poly(A) Polymerase
G8D99_RS12740	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
G8D99_RS12745	ENOG4105DXN	mazG family
G8D99_RS12750	ENOG4105EMU	Dehydrogenase
G8D99_RS12755	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G8D99_RS12770	ENOG4105C6T	cysteine synthase
G8D99_RS12775	ENOG4105BZU	Histidine kinase
G8D99_RS12780	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
G8D99_RS12785	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8D99_RS12790	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
G8D99_RS12815	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G8D99_RS12820	ENOG4105W8H	transhydrogenase (subunit alpha
G8D99_RS12825	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G8D99_RS12845	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G8D99_RS12850	ENOG4105CUZ	uba thif-type nad fad binding protein
G8D99_RS12855	ENOG4105F8V	Hydrolase, tatD family
G8D99_RS12870	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G8D99_RS12875	ENOG4105BZU	Histidine kinase
G8D99_RS12880	ENOG4105CN1	protease
G8D99_RS12905	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
G8D99_RS12910	ENOG4108DNC	Involved in acetate metabolism (By similarity)
G8D99_RS12915	ENOG4107GFK	fumarate
G8D99_RS12940	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G8D99_RS12950	ENOG4108ESX	Receptor
G8D99_RS12960	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G8D99_RS12965	ENOG4105DWV	Homoserine O-trans-acetylase
G8D99_RS12970	ENOG4105DWV	Homoserine O-trans-acetylase
G8D99_RS13065	ENOG4105SG9	biopolymer transport protein, ExbD
G8D99_RS13080	ENOG4105CIY	formyltetrahydrofolate deformylase
G8D99_RS13085	ENOG41062JF	Transcriptional regulator
G8D99_RS13090	ENOG4107RGH	Aldehyde dehydrogenase
G8D99_RS13105	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G8D99_RS13125	ENOG4105C4R	Atp-dependent dna helicase
G8D99_RS13130	ENOG4105BZW	Glycerate kinase
G8D99_RS13140	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
G8D99_RS13155	ENOG41069P5	Protein slyX homolog
G8D99_RS13160	ENOG4105C5H	ABC transporter
G8D99_RS13175	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G8D99_RS13200	ENOG4105CQM	Urea amidohydrolase subunit alpha
G8D99_RS13220	ENOG4105D1S	lipid A biosynthesis
G8D99_RS13245	ENOG4105HDK	L-asparaginase
G8D99_RS13270	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G8D99_RS13285	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G8D99_RS13305	ENOG4105CY2	Citrate transporter
G8D99_RS13325	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
G8D99_RS13335	ENOG4105CSU	acyl-Coa dehydrogenase
G8D99_RS13355	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
G8D99_RS13360	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
G8D99_RS13365	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
G8D99_RS13380	ENOG4105FUY	alpha subunit
G8D99_RS13385	ENOG4108W5M	transcriptional regulator
G8D99_RS13395	ENOG4105EPF	Outer membrane porin
G8D99_RS13400	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
G8D99_RS13405	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
G8D99_RS13410	ENOG4105IKQ	hydratase
G8D99_RS13420	ENOG4105EI2	Pseudouridine synthase
G8D99_RS13425	ENOG4105C03	ribonuclease
G8D99_RS13430	ENOG4105J5T	Amp-dependent synthetase and ligase
G8D99_RS13460	ENOG41067S9	phage shock protein C, PspC
G8D99_RS13485	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G8D99_RS13515	ENOG4105C5I	Dehydrogenase
G8D99_RS13565	ENOG4105IPI	Membrane
G8D99_RS13570	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8D99_RS13575	ENOG4105EM2	membrane
G8D99_RS13585	ENOG4107QF7	multi-drug
G8D99_RS13605	ENOG4105CQB	FAD linked oxidase domain protein
G8D99_RS13610	ENOG4108JQ1	Dehydrogenase
G8D99_RS13615	ENOG4107AQZ	Membrane
G8D99_RS13620	ENOG4107AQZ	Membrane
G8D99_RS13635	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G8D99_RS13640	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
G8D99_RS13645	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8D99_RS13650	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8D99_RS13655	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8D99_RS13660	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G8D99_RS13670	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G8D99_RS13675	ENOG4105K5M	30s ribosomal protein S16
G8D99_RS13685	ENOG4108VAU	general secretion pathway protein G
G8D99_RS13775	ENOG4105X0D	Fimbrial protein
G8D99_RS13810	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G8D99_RS13815	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G8D99_RS13820	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G8D99_RS13825	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G8D99_RS13830	ENOG4105KME	endoribonuclease L-psp
G8D99_RS13835	ENOG4105W53	bacterioferritin-associated ferredoxin
G8D99_RS13840	ENOG4108UQY	Iron-storage protein
G8D99_RS13845	ENOG4108YSG	O-Antigen polymerase
G8D99_RS13855	ENOG4105KHS	type IV fimbrial pilin protein
G8D99_RS13865	ENOG4105HA9	of methanol dehydrogenase type
G8D99_RS13870	ENOG4108V0P	LemA family
G8D99_RS13880	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G8D99_RS13890	ENOG4105CHV	Transcription elongation factor NusA
G8D99_RS13895	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G8D99_RS13920	ENOG4107EJC	Preprotein translocase subunit SecG
G8D99_RS13930	ENOG4107QHF	type ii secretion system protein e
G8D99_RS13945	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G8D99_RS13955	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G8D99_RS13970	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G8D99_RS13980	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G8D99_RS14010	ENOG4105BZ1	(ABC) transporter
G8D99_RS14015	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G8D99_RS14030	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
G8D99_RS14045	ENOG4108QCI	YvbH-like oligomerisation region
G8D99_RS14055	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8D99_RS14060	ENOG4105CHU	acetyl-coa acetyltransferase
G8D99_RS14085	ENOG4105BZU	Histidine kinase
G8D99_RS14095	ENOG4107ZXU	DSBA oxidoreductase
G8D99_RS14115	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
G8D99_RS14130	ENOG4105D3Y	Na H antiporter
G8D99_RS14160	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G8D99_RS14165	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G8D99_RS14170	ENOG4108VZM	50s ribosomal protein L10
G8D99_RS14175	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G8D99_RS14180	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G8D99_RS14185	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G8D99_RS14190	ENOG4105PM1	preprotein translocase subunit SecE
G8D99_RS14230	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G8D99_RS14240	ENOG4105GVR	general secretion pathway protein D
G8D99_RS14255	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
G8D99_RS14280	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G8D99_RS14285	ENOG4108NEV	two component transcriptional regulator, LytTR family
G8D99_RS14290	ENOG4108HRK	Histidine kinase
G8D99_RS14305	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G8D99_RS14335	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
G8D99_RS14345	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G8D99_RS14355	ENOG4105CNI	cell division protein FtsW
G8D99_RS14370	ENOG4105CE1	Ferrous iron transport protein b
G8D99_RS14380	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8D99_RS14385	ENOG4105T95	Thiol disulfide interChange protein
G8D99_RS14390	ENOG4105D6E	homoserine dehydrogenase
G8D99_RS14400	ENOG41061WM	D-Alanyl-D-Alanine
G8D99_RS14410	ENOG4105BZU	Histidine kinase
G8D99_RS14415	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8D99_RS14420	ENOG4105CN1	protease
G8D99_RS14425	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G8D99_RS14430	ENOG4108K5H	permease YjgP YjgQ family protein
G8D99_RS14435	ENOG4108M8S	permease YjgP YjgQ family protein
G8D99_RS14455	ENOG4105DQR	SNARE associated Golgi
G8D99_RS14470	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G8D99_RS14475	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G8D99_RS14480	ENOG4105BZU	Histidine kinase
G8D99_RS14485	ENOG4108YZA	Nitrogen regulatory protein pii
G8D99_RS14495	ENOG4105C0P	Mg chelatase subunit ChlI
G8D99_RS14510	ENOG41090KI	Outer membrane porin
G8D99_RS14515	ENOG4105F0N	pyrophosphate phospho-hydrolase
G8D99_RS14530	ENOG4105CEY	Amp-dependent synthetase and ligase
G8D99_RS14535	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8D99_RS14540	ENOG41079KZ	Major Facilitator Superfamily
G8D99_RS14545	ENOG4105EN6	Membrane
G8D99_RS14555	ENOG4105EE5	Membrane protein terC
G8D99_RS14560	ENOG4108URH	decarboxylase
G8D99_RS14580	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G8D99_RS14595	ENOG4105CCT	upf0313 protein
G8D99_RS14605	ENOG4105D94	Major Facilitator Superfamily
G8D99_RS14610	ENOG4107RKG	DJ-1/PfpI family
G8D99_RS14625	ENOG4105D2S	major facilitator superfamily
G8D99_RS14670	ENOG4108WZM	domain protein
G8D99_RS14675	ENOG4105C79	DNA protecting protein DprA
G8D99_RS14695	ENOG4108V06	Glutathione peroxidase
G8D99_RS14730	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G8D99_RS14740	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G8D99_RS14780	ENOG4105FDK	ABC transporter
G8D99_RS14785	ENOG4105FAV	ABC, transporter
G8D99_RS14790	ENOG4108NIW	Leucine export protein LeuE
G8D99_RS14795	ENOG410829K	Lysine exporter protein (Lyse ygga)
G8D99_RS14800	ENOG4105EZR	dyp-type peroxidase family protein
G8D99_RS14820	ENOG4105CS6	Rhs element vgr protein
G8D99_RS14825	ENOG4107R1I	NAD-dependent malic enzyme
G8D99_RS14855	ENOG4105EUB	pirin domain protein
G8D99_RS14870	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G8D99_RS14875	ENOG4108VBZ	doxx family
G8D99_RS14880	ENOG4105DQR	SNARE associated Golgi
G8D99_RS14900	ENOG4105M85	Bola protein
G8D99_RS14915	ENOG41084CK	capsule polysaccharide
G8D99_RS14920	ENOG4105E12	capsule polysaccharide
G8D99_RS14950	ENOG4107V1M	polysaccharide export protein
G8D99_RS14955	ENOG4105ECX	polysaccharide export
G8D99_RS14965	ENOG41090SZ	ABC-2 type transporter
G8D99_RS14975	ENOG4107QKV	phosphomannomutase
G8D99_RS14980	ENOG4105CMR	udp-glucose 4-epimerase
G8D99_RS14990	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G8D99_RS14995	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G8D99_RS15000	ENOG4105D3Q	Sugar transferase
G8D99_RS15010	ENOG4107QPH	glycogen) synthase
G8D99_RS15020	ENOG4105CG5	Glycosyl transferase (Group 1
G8D99_RS15035	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G8D99_RS15040	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
G8D99_RS15045	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
G8D99_RS15050	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G8D99_RS15060	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G8D99_RS15065	ENOG4107WZ3	Transferase
G8D99_RS15070	ENOG4105D3Q	Sugar transferase
G8D99_RS15075	ENOG4105CGN	Glycosyl transferase (Group 1
G8D99_RS15080	ENOG4107T8Q	Glycosyl transferase (Group 1
G8D99_RS15085	ENOG4105CG5	Glycosyl transferase (Group 1
G8D99_RS15110	ENOG4107QQG	Dehydrogenase
G8D99_RS15115	ENOG4105DAY	polysaccharide export protein
G8D99_RS15125	ENOG4105D75	Capsular exopolysaccharide family
G8D99_RS15130	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G8D99_RS15135	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G8D99_RS15140	ENOG4105CJR	Integral membrane protein (MviN
G8D99_RS15150	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G8D99_RS15185	ENOG4108Z33	Thiol disulfide Interchange Protein
G8D99_RS15190	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G8D99_RS15195	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G8D99_RS15200	ENOG4105UBK	short-chain dehydrogenase reductase
G8D99_RS15235	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G8D99_RS15245	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
G8D99_RS15255	ENOG4105C2W	permease
G8D99_RS15300	ENOG4105X0I	Fimbrial
G8D99_RS15335	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G8D99_RS15345	ENOG4105C8J	)-transporter
G8D99_RS15350	ENOG4108XC3	NADH ubiquinone oxidoreductase
G8D99_RS15395	ENOG4105CVE	Lytic murein transglycosylase
G8D99_RS15400	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G8D99_RS15405	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G8D99_RS15415	ENOG4105DFU	Cell wall formation (By similarity)
G8D99_RS15435	ENOG410830R	acetyltransferase
G8D99_RS15440	ENOG4105F27	Major Facilitator
G8D99_RS15445	ENOG4105DU1	integral membrane protein, terc
G8D99_RS15455	ENOG4107QUY	Guanine deaminase
G8D99_RS15460	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G8D99_RS15485	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G8D99_RS15490	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)