locus-tag	class	description
G8E00_RS00015	COG0594	ribonuclease P activity
G8E00_RS00020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G8E00_RS00025	COG0706	membrane insertase activity
G8E00_RS00050	COG1230	cation diffusion facilitator family transporter
G8E00_RS00055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G8E00_RS00060	COG2261	transglycosylase associated protein
G8E00_RS00070	COG0402	S-adenosylhomocysteine deaminase activity
G8E00_RS00090	COG0754	glutathionylspermidine amidase activity
G8E00_RS00110	COG0861	Integral membrane protein TerC family
G8E00_RS00120	COG2388	GCN5-related N-acetyl-transferase
G8E00_RS00130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G8E00_RS00150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G8E00_RS00155	COG2951	lytic endotransglycosylase activity
G8E00_RS00205	COG1012	belongs to the aldehyde dehydrogenase family
G8E00_RS00210	COG3738	Protein conserved in bacteria
G8E00_RS00215	COG0733	neurotransmitter:sodium symporter activity
G8E00_RS00225	COG0428	transporter
G8E00_RS00320	COG0129	dihydroxy-acid dehydratase activity
G8E00_RS00335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G8E00_RS00345	COG0583	DNA-binding transcription factor activity
G8E00_RS00350	COG2233	PERMEase
G8E00_RS00355	COG3706	GGDEF domain
G8E00_RS00370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E00_RS00395	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS00400	COG0546	phosphoglycolate phosphatase activity
G8E00_RS00405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G8E00_RS00420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G8E00_RS00420	COG1017	nitric oxide dioxygenase activity
G8E00_RS00445	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G8E00_RS00455	COG1368	sulfuric ester hydrolase activity
G8E00_RS00465	COG3023	N-Acetylmuramoyl-L-alanine amidase
G8E00_RS00470	COG0728	peptidoglycan biosynthetic process
G8E00_RS00495	COG1596	polysaccharide export
G8E00_RS00500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G8E00_RS00520	COG0438	transferase activity, transferring glycosyl groups
G8E00_RS00540	COG1215	transferase activity, transferring glycosyl groups
G8E00_RS00555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G8E00_RS00570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G8E00_RS00575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G8E00_RS00630	COG0271	Belongs to the BolA IbaG family
G8E00_RS00640	COG1192	Involved in chromosome partitioning
G8E00_RS00655	COG0586	Pfam SNARE associated Golgi protein
G8E00_RS00665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G8E00_RS00665	COG0519	Catalyzes the synthesis of GMP from XMP
G8E00_RS00670	COG1715	Restriction endonuclease
G8E00_RS00675	COG3706	GGDEF domain
G8E00_RS00745	COG4266	Belongs to the allantoicase family
G8E00_RS00750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E00_RS00765	COG2233	PERMEase
G8E00_RS00770	COG2351	hydroxyisourate hydrolase activity
G8E00_RS00815	COG1393	Belongs to the ArsC family
G8E00_RS00820	COG0708	Exodeoxyribonuclease III
G8E00_RS00830	COG0456	acetyltransferase
G8E00_RS00850	COG2720	vancomycin resistance protein
G8E00_RS00855	COG2226	methyltransferase
G8E00_RS00860	COG0189	ligase activity
G8E00_RS00880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G8E00_RS00910	COG4942	peptidase
G8E00_RS00930	COG2119	membrane
G8E00_RS00935	COG0426	domain, Protein
G8E00_RS00935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E00_RS00960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G8E00_RS01025	COG1902	pentaerythritol trinitrate reductase activity
G8E00_RS01030	COG1519	Transferase
G8E00_RS01035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G8E00_RS01040	COG0668	transmembrane transport
G8E00_RS01045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G8E00_RS01070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E00_RS01090	COG0784	Response regulator, receiver
G8E00_RS01090	COG2205	protein histidine kinase activity
G8E00_RS01095	COG3162	membrane
G8E00_RS01120	COG3706	GGDEF domain
G8E00_RS01135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G8E00_RS01145	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G8E00_RS01155	COG2814	Major facilitator Superfamily
G8E00_RS01160	COG0629	single-stranded DNA binding
G8E00_RS01210	COG0778	Nitroreductase
G8E00_RS01220	COG1733	regulation of RNA biosynthetic process
G8E00_RS01235	COG1335	isochorismatase
G8E00_RS01245	COG0493	'glutamate synthase
G8E00_RS01270	COG3158	transport of potassium into the cell
G8E00_RS01295	COG2207	Transcriptional regulator
G8E00_RS01300	COG0107	imidazoleglycerol-phosphate synthase activity
G8E00_RS01305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G8E00_RS01310	COG1278	Cold shock
G8E00_RS01320	COG2329	Antibiotic biosynthesis monooxygenase
G8E00_RS01355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G8E00_RS01395	COG0427	acetyl-CoA hydrolase
G8E00_RS01400	COG2205	protein histidine kinase activity
G8E00_RS01405	COG0745	RESPONSE REGULATOR receiver
G8E00_RS01435	COG0659	secondary active sulfate transmembrane transporter activity
G8E00_RS01450	COG0583	DNA-binding transcription factor activity
G8E00_RS01455	COG4221	oxidoreductase activity
G8E00_RS01460	COG2873	o-acetylhomoserine
G8E00_RS01465	COG0488	(ABC) transporter
G8E00_RS01510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G8E00_RS01540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G8E00_RS01545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G8E00_RS01555	COG2226	methyltransferase
G8E00_RS01605	COG0067	glutamate synthase
G8E00_RS01605	COG0069	glutamate synthase activity
G8E00_RS01605	COG0070	glutamate synthase
G8E00_RS01610	COG0493	'glutamate synthase
G8E00_RS01620	COG0307	riboflavin synthase, alpha
G8E00_RS01630	COG2212	antiporter activity
G8E00_RS01640	COG0651	ATP synthesis coupled electron transport
G8E00_RS01645	COG1006	Multisubunit Na H antiporter MnhC subunit
G8E00_RS01650	COG2111	Na H antiporter
G8E00_RS01650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G8E00_RS01655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G8E00_RS01665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G8E00_RS01680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G8E00_RS01710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G8E00_RS01715	COG1074	ATP-dependent DNA helicase activity
G8E00_RS01720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G8E00_RS01735	COG1185	polyribonucleotide nucleotidyltransferase activity
G8E00_RS01740	COG0598	Magnesium transport protein CorA
G8E00_RS01745	COG2841	Protein conserved in bacteria
G8E00_RS01760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G8E00_RS01770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G8E00_RS01790	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G8E00_RS01795	COG4535	Mg2 and Co2 transporter CorC
G8E00_RS01810	COG3501	Rhs element vgr protein
G8E00_RS01835	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G8E00_RS01835	COG0644	oxidoreductase
G8E00_RS01845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G8E00_RS01860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G8E00_RS01865	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G8E00_RS01875	COG0493	'glutamate synthase
G8E00_RS01890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G8E00_RS01895	COG0254	rRNA binding
G8E00_RS01900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G8E00_RS01905	COG0534	Mate efflux family protein
G8E00_RS01915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G8E00_RS01920	COG2194	sulfuric ester hydrolase activity
G8E00_RS01925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G8E00_RS01935	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS01950	COG0408	coproporphyrinogen oxidase activity
G8E00_RS01955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G8E00_RS01970	COG0513	Belongs to the DEAD box helicase family
G8E00_RS01975	COG1127	ABC transporter
G8E00_RS01980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G8E00_RS01985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G8E00_RS01990	COG2854	intermembrane phospholipid transfer
G8E00_RS02000	COG0598	Magnesium transport protein CorA
G8E00_RS02010	COG0494	nUDIX hydrolase
G8E00_RS02015	COG1040	competence protein
G8E00_RS02020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G8E00_RS02040	COG2937	Belongs to the GPAT DAPAT family
G8E00_RS02045	COG1946	Acyl-CoA thioesterase
G8E00_RS02055	COG1301	dicarboxylic acid transport
G8E00_RS02070	COG4993	Dehydrogenase
G8E00_RS02075	COG1959	2 iron, 2 sulfur cluster binding
G8E00_RS02080	COG1017	nitric oxide dioxygenase activity
G8E00_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G8E00_RS02085	COG0433	COG0433 Predicted ATPase
G8E00_RS02090	COG0626	cystathionine gamma-synthase activity
G8E00_RS02100	COG0051	transcription antitermination factor activity, RNA binding
G8E00_RS02105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G8E00_RS02110	COG0088	Forms part of the polypeptide exit tunnel
G8E00_RS02125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G8E00_RS02155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G8E00_RS02175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G8E00_RS02180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G8E00_RS02190	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G8E00_RS02225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G8E00_RS02230	COG0202	RNA polymerase activity
G8E00_RS02235	COG0203	ribosomal protein L17
G8E00_RS02240	COG2072	flavoprotein involved in K transport
G8E00_RS02245	COG3971	2-oxopent-4-enoate hydratase activity
G8E00_RS02250	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G8E00_RS02270	COG0583	DNA-binding transcription factor activity
G8E00_RS02275	COG4638	Rieske (2fe-2S)
G8E00_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS02295	COG3384	dioxygenase
G8E00_RS02300	COG0446	pyridine nucleotide-disulphide oxidoreductase
G8E00_RS02340	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS02345	COG0300	oxidoreductase activity
G8E00_RS02370	COG0494	nUDIX hydrolase
G8E00_RS02385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8E00_RS02415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G8E00_RS02435	COG0473	3-isopropylmalate dehydrogenase activity
G8E00_RS02460	COG0252	asparaginase activity
G8E00_RS02500	COG1560	Kdo2-lipid A biosynthetic process
G8E00_RS02505	COG3594	Acyltransferase
G8E00_RS02530	COG0804	urea catabolic process
G8E00_RS02545	COG0494	nUDIX hydrolase
G8E00_RS02565	COG0830	nickel cation binding
G8E00_RS02585	COG2900	Belongs to the SlyX family
G8E00_RS02595	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS02600	COG1733	regulation of RNA biosynthetic process
G8E00_RS02625	COG1929	Belongs to the glycerate kinase type-1 family
G8E00_RS02635	COG0210	DNA helicase
G8E00_RS02670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G8E00_RS02670	COG4651	solute:proton antiporter activity
G8E00_RS02695	COG0788	formyltetrahydrofolate deformylase activity
G8E00_RS02805	COG2813	Specifically methylates the guanine in position
G8E00_RS02805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G8E00_RS02810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G8E00_RS02815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G8E00_RS02830	COG4774	siderophore transport
G8E00_RS02835	COG4774	siderophore transport
G8E00_RS02845	COG0740	serine-type endopeptidase activity
G8E00_RS02865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G8E00_RS02865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G8E00_RS02875	COG0857	belongs to the CobB CobQ family
G8E00_RS02875	COG0280	phosphate acetyltransferase
G8E00_RS02880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G8E00_RS02905	COG0793	Belongs to the peptidase S41A family
G8E00_RS02915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G8E00_RS02930	COG0084	hydrolase, TatD family'
G8E00_RS02945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G8E00_RS02955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G8E00_RS03040	COG2814	Major facilitator Superfamily
G8E00_RS03075	COG0583	DNA-binding transcription factor activity
G8E00_RS03080	COG1053	succinate dehydrogenase
G8E00_RS03095	COG0004	ammonium transporteR
G8E00_RS03110	COG3622	Belongs to the hyi family
G8E00_RS03115	COG2084	Dehydrogenase
G8E00_RS03120	COG1024	Enoyl-CoA hydratase
G8E00_RS03125	COG2205	protein histidine kinase activity
G8E00_RS03125	COG5002	protein histidine kinase activity
G8E00_RS03125	COG0784	Response regulator, receiver
G8E00_RS03145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G8E00_RS03160	COG3956	TIGRFAM MazG family protein
G8E00_RS03165	COG1555	photosystem II stabilization
G8E00_RS03170	COG0617	tRNA 3'-terminal CCA addition
G8E00_RS03175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G8E00_RS03190	COG1660	Displays ATPase and GTPase activities
G8E00_RS03195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G8E00_RS03210	COG0318	PFAM AMP-dependent synthetase and ligase
G8E00_RS03225	COG0069	glutamate synthase activity
G8E00_RS03245	COG0625	glutathione transferase activity
G8E00_RS03250	COG1238	metal cluster binding
G8E00_RS03300	COG0072	phenylalanine-tRNA ligase activity
G8E00_RS03305	COG0776	regulation of translation
G8E00_RS03325	COG0248	Ppx GppA phosphatase
G8E00_RS03335	COG0037	tRNA processing
G8E00_RS03395	COG1764	response to oxidative stress
G8E00_RS03400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G8E00_RS03415	COG2853	Lipoprotein
G8E00_RS03450	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS03455	COG1309	transcriptional regulator
G8E00_RS03470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G8E00_RS03475	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS03480	COG1024	Enoyl-CoA hydratase
G8E00_RS03480	COG1250	3-hydroxyacyl-CoA dehydrogenase
G8E00_RS03515	COG2969	positive regulation of protein catabolic process
G8E00_RS03520	COG0625	glutathione transferase activity
G8E00_RS03530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G8E00_RS03535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G8E00_RS03540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G8E00_RS03545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G8E00_RS03550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G8E00_RS03575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G8E00_RS03585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G8E00_RS03590	COG1408	metallophosphoesterase
G8E00_RS03595	COG0477	Major facilitator Superfamily
G8E00_RS03600	COG1272	protein, Hemolysin III
G8E00_RS03615	COG0456	acetyltransferase
G8E00_RS03620	COG1011	Hydrolase
G8E00_RS03630	COG1024	Enoyl-CoA hydratase
G8E00_RS03630	COG1250	3-hydroxyacyl-CoA dehydrogenase
G8E00_RS03635	COG0183	Belongs to the thiolase family
G8E00_RS03645	COG2207	Transcriptional regulator
G8E00_RS03695	COG0285	dihydrofolate synthase activity
G8E00_RS03715	COG0450	alkyl hydroperoxide reductase
G8E00_RS03730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G8E00_RS03735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G8E00_RS03760	COG2885	chlorophyll binding
G8E00_RS03765	COG2199	diguanylate cyclase activity
G8E00_RS03800	COG2814	Major facilitator Superfamily
G8E00_RS03805	COG1126	abc transporter atp-binding protein
G8E00_RS03810	COG0765	amino acid transport
G8E00_RS03815	COG0765	amino acid transport
G8E00_RS03820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G8E00_RS03845	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G8E00_RS03855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G8E00_RS03905	COG0494	nUDIX hydrolase
G8E00_RS03920	COG1968	undecaprenyl-diphosphatase activity
G8E00_RS03935	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G8E00_RS03955	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G8E00_RS03965	COG2132	Multicopper oxidase
G8E00_RS03970	COG3667	copper resistance
G8E00_RS03975	COG2076	Multidrug Resistance protein
G8E00_RS03995	COG0028	Belongs to the TPP enzyme family
G8E00_RS04000	COG0352	thiamine-phosphate diphosphorylase activity
G8E00_RS04000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G8E00_RS04000	COG0351	phosphomethylpyrimidine kinase
G8E00_RS04025	COG0251	oxidation-reduction process
G8E00_RS04030	COG1113	amino acid transport
G8E00_RS04055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G8E00_RS04080	COG0456	acetyltransferase
G8E00_RS04090	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G8E00_RS04095	COG0492	ferredoxin-NADP+ reductase activity
G8E00_RS04100	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G8E00_RS04100	COG1674	ftsk spoiiie
G8E00_RS04135	COG0204	Acyl-transferase
G8E00_RS04140	COG2885	chlorophyll binding
G8E00_RS04145	COG2885	chlorophyll binding
G8E00_RS04150	COG0210	DNA helicase
G8E00_RS04155	COG0756	dUTP diphosphatase activity
G8E00_RS04160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G8E00_RS04165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G8E00_RS04170	COG0121	glutamine amidotransferase
G8E00_RS04185	COG2914	Belongs to the UPF0125 (RnfH) family
G8E00_RS04190	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E00_RS04195	COG0735	belongs to the Fur family
G8E00_RS04230	COG0420	3'-5' exonuclease activity
G8E00_RS04250	COG2050	protein possibly involved in aromatic compounds catabolism
G8E00_RS04255	COG1566	PFAM secretion protein HlyD family protein
G8E00_RS04260	COG2814	Major facilitator Superfamily
G8E00_RS04265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G8E00_RS04275	COG1401	restriction endodeoxyribonuclease activity
G8E00_RS04290	COG4771	TonB-dependent receptor
G8E00_RS04295	COG1429	ligase activity, forming nitrogen-metal bonds
G8E00_RS04325	COG4774	siderophore transport
G8E00_RS04380	COG3706	GGDEF domain
G8E00_RS04395	COG3706	GGDEF domain
G8E00_RS04400	COG0242	peptide deformylase activity
G8E00_RS04410	COG2066	Belongs to the glutaminase family
G8E00_RS04420	COG2376	Dihydroxyacetone kinase
G8E00_RS04445	COG0306	phosphate transporter
G8E00_RS04460	COG4607	ABC-type enterochelin transport system periplasmic component
G8E00_RS04475	COG4771	TonB-dependent receptor
G8E00_RS04500	COG4181	ATPase activity
G8E00_RS04505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G8E00_RS04525	COG0583	DNA-binding transcription factor activity
G8E00_RS04530	COG2267	carboxylic ester hydrolase activity
G8E00_RS04535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E00_RS04540	COG1773	rubredoxin
G8E00_RS04545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G8E00_RS04575	COG0175	sulfate reduction
G8E00_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS04625	COG3338	carbonate dehydratase activity
G8E00_RS04660	COG0525	valine-tRNA ligase activity
G8E00_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS04680	COG0393	Putative heavy-metal-binding
G8E00_RS04685	COG0393	Putative heavy-metal-binding
G8E00_RS04700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E00_RS04705	COG0671	phosphoesterase, PA-phosphatase related
G8E00_RS04720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G8E00_RS04730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G8E00_RS04740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G8E00_RS04745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G8E00_RS04745	COG1648	precorrin-2 dehydrogenase activity
G8E00_RS04750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G8E00_RS04760	COG0531	amino acid
G8E00_RS04775	COG0321	lipoyl(octanoyl) transferase activity
G8E00_RS04800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G8E00_RS04860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G8E00_RS04890	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G8E00_RS04905	COG0358	DNA primase activity
G8E00_RS04915	COG0564	pseudouridine synthase activity
G8E00_RS04930	COG3293	Transposase
G8E00_RS04940	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G8E00_RS04950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G8E00_RS04985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G8E00_RS04985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G8E00_RS04995	COG0714	Associated with various cellular activities
G8E00_RS05000	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G8E00_RS05015	COG0300	oxidoreductase activity
G8E00_RS05020	COG2072	flavoprotein involved in K transport
G8E00_RS05035	COG2009	succinate dehydrogenase
G8E00_RS05040	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G8E00_RS05045	COG1053	succinate dehydrogenase
G8E00_RS05050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G8E00_RS05065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8E00_RS05075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G8E00_RS05085	COG0742	ribosomal rna small subunit methyltransferase
G8E00_RS05090	COG0768	penicillin binding
G8E00_RS05115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G8E00_RS05120	COG2878	Part of a membrane complex involved in electron transport
G8E00_RS05125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G8E00_RS05135	COG3384	dioxygenase
G8E00_RS05145	COG2234	aminopeptidase activity
G8E00_RS05155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G8E00_RS05165	COG2217	Heavy metal translocating P-type atpase
G8E00_RS05180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G8E00_RS05185	COG0022	dehydrogenase e1 component
G8E00_RS05190	COG0508	dehydrogenase complex catalyzes the overall conversion of
G8E00_RS05195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8E00_RS05210	COG0640	Transcriptional regulator
G8E00_RS05280	COG0280	phosphate acetyltransferase
G8E00_RS05280	COG0281	malic enzyme
G8E00_RS05290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G8E00_RS05295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G8E00_RS05300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G8E00_RS05330	COG0583	DNA-binding transcription factor activity
G8E00_RS05335	COG0596	Alpha beta hydrolase
G8E00_RS05340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E00_RS05345	COG1335	isochorismatase
G8E00_RS05350	COG0251	oxidation-reduction process
G8E00_RS05355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E00_RS05360	COG2233	PERMEase
G8E00_RS05375	COG0183	Belongs to the thiolase family
G8E00_RS05410	COG0833	amino acid
G8E00_RS05425	COG0833	amino acid
G8E00_RS05430	COG1671	Belongs to the UPF0178 family
G8E00_RS05450	COG1136	(ABC) transporter
G8E00_RS05480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G8E00_RS05485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G8E00_RS05490	COG0628	permease
G8E00_RS05535	COG3634	alkyl hydroperoxide reductase activity
G8E00_RS05540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G8E00_RS05550	COG0640	Transcriptional regulator
G8E00_RS05555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G8E00_RS05560	COG0798	PFAM Bile acid sodium symporter
G8E00_RS05565	COG0431	NADPH-dependent FMN reductase
G8E00_RS05590	COG1720	tRNA m6t6A37 methyltransferase activity
G8E00_RS05600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G8E00_RS05620	COG0642	Histidine kinase
G8E00_RS05640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G8E00_RS05645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G8E00_RS05650	COG3139	Protein of unknown function (DUF1315)
G8E00_RS05655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G8E00_RS05680	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
G8E00_RS05685	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS05700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G8E00_RS05715	COG1522	sequence-specific DNA binding
G8E00_RS05750	COG3209	COG3209 Rhs family protein
G8E00_RS05775	COG0415	Belongs to the DNA photolyase family
G8E00_RS05785	COG1252	NADH dehydrogenase
G8E00_RS05790	COG2885	chlorophyll binding
G8E00_RS05795	COG1686	Belongs to the peptidase S11 family
G8E00_RS05810	COG2351	hydroxyisourate hydrolase activity
G8E00_RS05840	COG0612	Peptidase, M16
G8E00_RS05870	COG1309	transcriptional regulator
G8E00_RS05875	COG1132	(ABC) transporter
G8E00_RS05900	COG0352	thiamine-phosphate diphosphorylase activity
G8E00_RS05940	COG1022	Amp-dependent synthetase and ligase
G8E00_RS05950	COG0583	DNA-binding transcription factor activity
G8E00_RS05955	COG1309	transcriptional regulator
G8E00_RS05975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G8E00_RS05980	COG0076	glutamate decarboxylase activity
G8E00_RS06000	COG0573	inorganic phosphate transmembrane transporter activity
G8E00_RS06010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G8E00_RS06015	COG0765	amino acid transport
G8E00_RS06025	COG1126	abc transporter atp-binding protein
G8E00_RS06030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G8E00_RS06035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G8E00_RS06040	COG4935	Belongs to the peptidase S8 family
G8E00_RS06040	COG2234	aminopeptidase activity
G8E00_RS06045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G8E00_RS06045	COG0047	phosphoribosylformylglycinamidine synthase activity
G8E00_RS06065	COG0583	DNA-binding transcription factor activity
G8E00_RS06070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G8E00_RS06070	COG3323	Protein of unknown function (DUF1653)
G8E00_RS06075	COG0778	Nitroreductase
G8E00_RS06080	COG1024	Enoyl-CoA hydratase
G8E00_RS06085	COG1056	cytidyltransferase-related domain
G8E00_RS06085	COG1051	belongs to the nudix hydrolase family
G8E00_RS06090	COG0583	DNA-binding transcription factor activity
G8E00_RS06100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8E00_RS06110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G8E00_RS06115	COG0602	queuosine metabolic process
G8E00_RS06130	COG0583	DNA-binding transcription factor activity
G8E00_RS06135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G8E00_RS06140	COG4208	sulfate ABC transporter
G8E00_RS06145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G8E00_RS06155	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G8E00_RS06160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G8E00_RS06165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G8E00_RS06185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G8E00_RS06215	COG0571	ribonuclease III activity
G8E00_RS06220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G8E00_RS06230	COG1381	Involved in DNA repair and RecF pathway recombination
G8E00_RS06235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G8E00_RS06285	COG0436	Aminotransferase
G8E00_RS06310	COG0556	nucleotide-excision repair
G8E00_RS06315	COG3040	lipid binding
G8E00_RS06320	COG2962	Rard protein
G8E00_RS06345	COG0702	epimerase
G8E00_RS06350	COG1733	regulation of RNA biosynthetic process
G8E00_RS06360	COG1278	Cold shock
G8E00_RS06365	COG2814	Major facilitator Superfamily
G8E00_RS06405	COG2318	DinB family
G8E00_RS06470	COG1643	Atp-dependent helicase
G8E00_RS06555	COG0402	S-adenosylhomocysteine deaminase activity
G8E00_RS06560	COG4521	taurine ABC transporter
G8E00_RS06565	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G8E00_RS06570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E00_RS06575	COG2175	clavaminate synthase activity
G8E00_RS06585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G8E00_RS06590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G8E00_RS06610	COG1116	anion transmembrane transporter activity
G8E00_RS06610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E00_RS06620	COG2223	nitrite transmembrane transporter activity
G8E00_RS06625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E00_RS06630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E00_RS06635	COG0243	molybdopterin cofactor binding
G8E00_RS06645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G8E00_RS06655	COG0314	molybdopterin synthase activity
G8E00_RS06660	COG0521	Mo-molybdopterin cofactor biosynthetic process
G8E00_RS06660	COG0315	cyclic pyranopterin monophosphate synthase activity
G8E00_RS06665	COG0303	'Molybdopterin
G8E00_RS06670	COG0725	ABC transporter, periplasmic molybdate-binding protein
G8E00_RS06675	COG4149	molybdate abc transporter
G8E00_RS06680	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G8E00_RS06695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G8E00_RS06695	COG0517	IMP dehydrogenase activity
G8E00_RS06700	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G8E00_RS06710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G8E00_RS06715	COG1137	ATPase activity
G8E00_RS06725	COG1132	(ABC) transporter
G8E00_RS06750	COG4122	O-methyltransferase activity
G8E00_RS06760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G8E00_RS06810	COG0436	Aminotransferase
G8E00_RS06815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G8E00_RS06820	COG0386	Belongs to the glutathione peroxidase family
G8E00_RS06830	COG2431	L-lysine efflux transmembrane transporter activity
G8E00_RS06840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G8E00_RS06845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G8E00_RS06870	COG1253	flavin adenine dinucleotide binding
G8E00_RS06895	COG0024	Methionine aminopeptidase
G8E00_RS06900	COG3135	benzoate transporter
G8E00_RS06910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G8E00_RS06915	COG0583	DNA-binding transcription factor activity
G8E00_RS06930	COG0183	Belongs to the thiolase family
G8E00_RS06935	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS06960	COG0824	Thioesterase
G8E00_RS06965	COG1454	alcohol dehydrogenase
G8E00_RS06970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G8E00_RS06995	COG0069	glutamate synthase activity
G8E00_RS07000	COG2850	peptidyl-arginine hydroxylation
G8E00_RS07020	COG0126	phosphoglycerate kinase activity
G8E00_RS07040	COG0697	spore germination
G8E00_RS07065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G8E00_RS07070	COG0730	response to heat
G8E00_RS07090	COG4773	Receptor
G8E00_RS07095	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8E00_RS07120	COG3121	Chaperone
G8E00_RS07175	COG2814	Major facilitator Superfamily
G8E00_RS07205	COG4589	Belongs to the CDS family
G8E00_RS07220	COG2453	phosphatase
G8E00_RS07220	COG0671	phosphoesterase, PA-phosphatase related
G8E00_RS07225	COG2267	carboxylic ester hydrolase activity
G8E00_RS07230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G8E00_RS07255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G8E00_RS07305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G8E00_RS07325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G8E00_RS07335	COG0133	tryptophan synthase activity
G8E00_RS07350	COG0517	IMP dehydrogenase activity
G8E00_RS07380	COG0612	Peptidase, M16
G8E00_RS07385	COG0552	protein localization to endoplasmic reticulum
G8E00_RS07420	COG4890	Cyd operon protein YbgT
G8E00_RS07425	COG1294	oxidase, subunit
G8E00_RS07440	COG1585	Membrane protein implicated in regulation of membrane protease activity
G8E00_RS07450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G8E00_RS07455	COG2153	protein acetylation
G8E00_RS07460	COG3539	Fimbrial protein
G8E00_RS07520	COG2031	fatty acid transporter
G8E00_RS07525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G8E00_RS07540	COG4770	biotin carboxylase activity
G8E00_RS07545	COG1024	Enoyl-CoA hydratase
G8E00_RS07550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G8E00_RS07555	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS07560	COG1309	transcriptional regulator
G8E00_RS07565	COG0318	PFAM AMP-dependent synthetase and ligase
G8E00_RS07570	COG2226	methyltransferase
G8E00_RS07570	COG0596	Alpha beta hydrolase
G8E00_RS07570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G8E00_RS07575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G8E00_RS07600	COG0318	PFAM AMP-dependent synthetase and ligase
G8E00_RS07605	COG2072	flavoprotein involved in K transport
G8E00_RS07615	COG1073	alpha beta
G8E00_RS07625	COG0642	Histidine kinase
G8E00_RS07630	COG0745	RESPONSE REGULATOR receiver
G8E00_RS07635	COG2194	sulfuric ester hydrolase activity
G8E00_RS07660	COG0500	methyltransferase
G8E00_RS07670	COG2223	nitrite transmembrane transporter activity
G8E00_RS07675	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G8E00_RS07690	COG1024	Enoyl-CoA hydratase
G8E00_RS07695	COG1250	3-hydroxyacyl-CoA dehydrogenase
G8E00_RS07700	COG0183	Belongs to the thiolase family
G8E00_RS07705	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS07710	COG1846	Transcriptional regulator
G8E00_RS07715	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS07720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G8E00_RS07730	COG0318	PFAM AMP-dependent synthetase and ligase
G8E00_RS07755	COG0439	Biotin carboxylase
G8E00_RS07760	COG1196	nuclear chromosome segregation
G8E00_RS07765	COG0864	Transcriptional regulator
G8E00_RS07780	COG0583	DNA-binding transcription factor activity
G8E00_RS07795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G8E00_RS07800	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS07805	COG1024	Enoyl-CoA hydratase
G8E00_RS07815	COG0477	Major facilitator Superfamily
G8E00_RS07820	COG4628	conserved protein (DUF2132)
G8E00_RS07865	COG0583	DNA-binding transcription factor activity
G8E00_RS07880	COG1741	Belongs to the pirin family
G8E00_RS07885	COG1335	isochorismatase
G8E00_RS07890	COG2259	Doxx family
G8E00_RS07895	COG1741	Belongs to the pirin family
G8E00_RS07945	COG3209	COG3209 Rhs family protein
G8E00_RS07970	COG3209	COG3209 Rhs family protein
G8E00_RS07980	COG2706	6-phosphogluconolactonase activity
G8E00_RS07985	COG1944	ATP diphosphatase activity
G8E00_RS07990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E00_RS07995	COG1116	anion transmembrane transporter activity
G8E00_RS08025	COG3209	COG3209 Rhs family protein
G8E00_RS08035	COG3501	Rhs element vgr protein
G8E00_RS08055	COG3122	Protein conserved in bacteria
G8E00_RS08080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G8E00_RS08110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G8E00_RS08130	COG1132	(ABC) transporter
G8E00_RS08155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G8E00_RS08160	COG5001	Diguanylate cyclase
G8E00_RS08160	COG3300	MHYT domain
G8E00_RS08165	COG0596	Alpha beta hydrolase
G8E00_RS08180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G8E00_RS08190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8E00_RS08195	COG0697	spore germination
G8E00_RS08240	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS08245	COG0583	DNA-binding transcription factor activity
G8E00_RS08250	COG3152	Membrane
G8E00_RS08260	COG1294	oxidase, subunit
G8E00_RS08265	COG1271	oxidase subunit
G8E00_RS08280	COG2814	Major facilitator Superfamily
G8E00_RS08295	COG1598	PFAM Uncharacterised protein family UPF0150
G8E00_RS08310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G8E00_RS08315	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G8E00_RS08350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G8E00_RS08360	COG0511	ligase activity, forming carbon-carbon bonds
G8E00_RS08365	COG0439	Biotin carboxylase
G8E00_RS08375	COG3706	GGDEF domain
G8E00_RS08380	COG2814	Major facilitator Superfamily
G8E00_RS08385	COG3042	response to heat
G8E00_RS08390	COG0589	response to stress
G8E00_RS08420	COG1278	Cold shock
G8E00_RS08440	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS08445	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS08475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G8E00_RS08480	COG2207	Transcriptional regulator
G8E00_RS08485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G8E00_RS08515	COG0822	iron-sulfur transferase activity
G8E00_RS08520	COG0316	Belongs to the HesB IscA family
G8E00_RS08550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G8E00_RS08570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G8E00_RS08575	COG0702	epimerase
G8E00_RS08595	COG1011	Hydrolase
G8E00_RS08600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G8E00_RS08605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G8E00_RS08610	COG2137	regulation of response to DNA damage stimulus
G8E00_RS08625	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8E00_RS08635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8E00_RS08645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E00_RS08660	COG0575	Belongs to the CDS family
G8E00_RS08665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G8E00_RS08685	COG3852	Histidine kinase
G8E00_RS08690	COG2204	response regulator
G8E00_RS08705	COG0372	Belongs to the citrate synthase family
G8E00_RS08735	COG0542	response to heat
G8E00_RS08740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G8E00_RS08765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G8E00_RS08770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G8E00_RS08780	COG0569	domain protein
G8E00_RS08785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G8E00_RS08795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G8E00_RS08800	COG0583	DNA-binding transcription factor activity
G8E00_RS08825	COG0667	Aldo Keto reductase
G8E00_RS08830	COG0583	DNA-binding transcription factor activity
G8E00_RS08880	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G8E00_RS08895	COG0778	Nitroreductase
G8E00_RS08905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G8E00_RS08915	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G8E00_RS08920	COG0148	phosphopyruvate hydratase activity
G8E00_RS08955	COG1902	pentaerythritol trinitrate reductase activity
G8E00_RS08955	COG0446	pyridine nucleotide-disulphide oxidoreductase
G8E00_RS08965	COG2267	carboxylic ester hydrolase activity
G8E00_RS08980	COG2814	Major facilitator Superfamily
G8E00_RS08985	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS08990	COG0583	DNA-binding transcription factor activity
G8E00_RS08995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G8E00_RS09005	COG1027	Aspartate ammonia-lyase
G8E00_RS09010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G8E00_RS09020	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G8E00_RS09020	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G8E00_RS09020	COG0506	proline dehydrogenase activity
G8E00_RS09030	COG0308	aminopeptidase N
G8E00_RS09065	COG4115	mRNA cleavage
G8E00_RS09075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G8E00_RS09105	COG0531	amino acid
G8E00_RS09110	COG4303	Ethanolamine ammonia lyase large subunit
G8E00_RS09115	COG4302	ethanolamine ammonia-lyase activity
G8E00_RS09135	COG1064	alcohol dehydrogenase
G8E00_RS09150	COG0405	Gamma-glutamyltransferase
G8E00_RS09155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G8E00_RS09155	COG0519	Catalyzes the synthesis of GMP from XMP
G8E00_RS09180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G8E00_RS09190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G8E00_RS09230	COG1254	Belongs to the acylphosphatase family
G8E00_RS09235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G8E00_RS09235	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G8E00_RS09270	COG3433	isochorismatase activity
G8E00_RS09270	COG1535	isochorismatase
G8E00_RS09275	COG1021	2,3-dihydroxybenzoate-AMP ligase
G8E00_RS09280	COG1169	isochorismate synthase
G8E00_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS09305	COG0477	Major facilitator Superfamily
G8E00_RS09330	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G8E00_RS09335	COG4771	TonB-dependent receptor
G8E00_RS09350	COG0204	Acyl-transferase
G8E00_RS09395	COG1464	Belongs to the NlpA lipoprotein family
G8E00_RS09405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G8E00_RS09410	COG2011	ABC-type metal ion transport system permease component
G8E00_RS09415	COG0012	GTP binding
G8E00_RS09425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G8E00_RS09435	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G8E00_RS09445	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G8E00_RS09455	COG0436	Aminotransferase
G8E00_RS09500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G8E00_RS09525	COG2165	general secretion pathway protein
G8E00_RS09535	COG0084	hydrolase, TatD family'
G8E00_RS09555	COG1663	tetraacyldisaccharide 4'-kinase activity
G8E00_RS09560	COG1132	(ABC) transporter
G8E00_RS09570	COG0811	peptide transport
G8E00_RS09575	COG1475	DNA binding
G8E00_RS09580	COG1192	Involved in chromosome partitioning
G8E00_RS09590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G8E00_RS09595	COG3178	'Phosphotransferase
G8E00_RS09605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G8E00_RS09610	COG1923	regulation of RNA biosynthetic process
G8E00_RS09620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G8E00_RS09625	COG0802	atpase or kinase
G8E00_RS09645	COG1187	pseudouridine synthase activity
G8E00_RS09660	COG2707	UPF0756 membrane protein
G8E00_RS09665	COG0668	transmembrane transport
G8E00_RS09670	COG0583	DNA-binding transcription factor activity
G8E00_RS09685	COG0786	glutamate:sodium symporter activity
G8E00_RS09700	COG2132	Multicopper oxidase
G8E00_RS09735	COG2911	Protein conserved in bacteria
G8E00_RS09740	COG0729	surface antigen
G8E00_RS09780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G8E00_RS09790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E00_RS09795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E00_RS09800	COG2890	protein-(glutamine-N5) methyltransferase activity
G8E00_RS09820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E00_RS09825	COG4682	membrane
G8E00_RS09845	COG1215	transferase activity, transferring glycosyl groups
G8E00_RS09850	COG1649	PFAM Uncharacterised BCR, COG1649
G8E00_RS09850	COG0726	polysaccharide deacetylase
G8E00_RS09880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G8E00_RS09885	COG1845	cytochrome c oxidase, subunit III
G8E00_RS09890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G8E00_RS09910	COG1505	serine-type exopeptidase activity
G8E00_RS09915	COG0360	Binds together with S18 to 16S ribosomal RNA
G8E00_RS09920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G8E00_RS09930	COG0305	Participates in initiation and elongation during chromosome replication
G8E00_RS09940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G8E00_RS09955	COG1305	Transglutaminase-like
G8E00_RS09965	COG2308	Evidence 4 Homologs of previously reported genes of
G8E00_RS09975	COG2814	Major facilitator Superfamily
G8E00_RS10005	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G8E00_RS10010	COG0138	bifunctional purine biosynthesis protein purh
G8E00_RS10025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G8E00_RS10040	COG1464	Belongs to the NlpA lipoprotein family
G8E00_RS10045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G8E00_RS10050	COG2011	ABC-type metal ion transport system permease component
G8E00_RS10130	COG1610	YqeY-like protein
G8E00_RS10140	COG4783	chaperone-mediated protein folding
G8E00_RS10195	COG0778	Nitroreductase
G8E00_RS10205	COG0513	Belongs to the DEAD box helicase family
G8E00_RS10210	COG1278	Cold shock
G8E00_RS10225	COG2363	Small membrane protein
G8E00_RS10230	COG0625	glutathione transferase activity
G8E00_RS10235	COG0659	secondary active sulfate transmembrane transporter activity
G8E00_RS10240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G8E00_RS10260	COG2885	chlorophyll binding
G8E00_RS10260	COG3047	cAMP biosynthetic process
G8E00_RS10280	COG0540	Belongs to the ATCase OTCase family
G8E00_RS10320	COG0542	response to heat
G8E00_RS10330	COG1765	OsmC-like protein
G8E00_RS10340	COG0667	Aldo Keto reductase
G8E00_RS10360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G8E00_RS10370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G8E00_RS10380	COG0527	aspartate kinase activity
G8E00_RS10390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G8E00_RS10400	COG3038	cytochrome b561
G8E00_RS10410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G8E00_RS10415	COG2252	PERMEase
G8E00_RS10475	COG0714	Associated with various cellular activities
G8E00_RS10485	COG1966	Carbon starvation protein
G8E00_RS10490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G8E00_RS10495	COG1509	lysine 2,3-aminomutase activity
G8E00_RS10525	COG2211	Major facilitator Superfamily
G8E00_RS10530	COG1067	ATP-dependent peptidase activity
G8E00_RS10540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G8E00_RS10545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G8E00_RS10550	COG0583	DNA-binding transcription factor activity
G8E00_RS10575	COG1686	Belongs to the peptidase S11 family
G8E00_RS10580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G8E00_RS10600	COG0482	sulfurtransferase activity
G8E00_RS10625	COG0616	signal peptide processing
G8E00_RS10645	COG2255	four-way junction helicase activity
G8E00_RS10655	COG0824	Thioesterase
G8E00_RS10675	COG0823	Involved in the tonB-independent uptake of proteins
G8E00_RS10680	COG2885	chlorophyll binding
G8E00_RS10695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8E00_RS10725	COG3040	lipid binding
G8E00_RS10760	COG1113	amino acid transport
G8E00_RS10770	COG1131	(ABC) transporter
G8E00_RS10775	COG0842	Transport permease protein
G8E00_RS10790	COG0772	Belongs to the SEDS family
G8E00_RS10795	COG2951	lytic endotransglycosylase activity
G8E00_RS10815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G8E00_RS10820	COG0052	Belongs to the universal ribosomal protein uS2 family
G8E00_RS10825	COG0024	Methionine aminopeptidase
G8E00_RS10840	COG2175	clavaminate synthase activity
G8E00_RS10845	COG0583	DNA-binding transcription factor activity
G8E00_RS10860	COG1289	transmembrane transporter activity
G8E00_RS10865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8E00_RS10870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G8E00_RS10875	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
G8E00_RS10890	COG4172	Belongs to the ABC transporter superfamily
G8E00_RS10895	COG4239	(ABC) transporter, permease
G8E00_RS10900	COG4174	ABC transporter (Permease)
G8E00_RS10910	COG1388	LysM domain
G8E00_RS10910	COG0741	lytic transglycosylase activity
G8E00_RS10915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G8E00_RS10925	COG2816	NAD+ diphosphatase activity
G8E00_RS10945	COG3107	peptidoglycan biosynthetic process
G8E00_RS10960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E00_RS10965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E00_RS10980	COG0006	proline dipeptidase activity
G8E00_RS11005	COG0730	response to heat
G8E00_RS11010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E00_RS11065	COG4774	siderophore transport
G8E00_RS11085	COG4580	involved in the transport of maltose and maltodextrins
G8E00_RS11100	COG0183	Belongs to the thiolase family
G8E00_RS11105	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G8E00_RS11110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G8E00_RS11115	COG3485	protocatechuate 3,4-dioxygenase
G8E00_RS11130	COG0673	inositol 2-dehydrogenase activity
G8E00_RS11135	COG4213	ABC transporter substrate-binding protein
G8E00_RS11145	COG4214	carbohydrate transport
G8E00_RS11150	COG0673	inositol 2-dehydrogenase activity
G8E00_RS11170	COG0446	pyridine nucleotide-disulphide oxidoreductase
G8E00_RS11170	COG1902	pentaerythritol trinitrate reductase activity
G8E00_RS11175	COG0277	FAD linked oxidase domain protein
G8E00_RS11185	COG2186	Transcriptional regulator
G8E00_RS11190	COG1620	l-lactate permease
G8E00_RS11195	COG0737	Belongs to the 5'-nucleotidase family
G8E00_RS11205	COG4251	negative regulation of phosphorylation
G8E00_RS11205	COG3706	GGDEF domain
G8E00_RS11205	COG2203	Gaf domain
G8E00_RS11205	COG5001	Diguanylate cyclase
G8E00_RS11210	COG4251	negative regulation of phosphorylation
G8E00_RS11210	COG3706	GGDEF domain
G8E00_RS11210	COG5001	Diguanylate cyclase
G8E00_RS11210	COG2203	Gaf domain
G8E00_RS11215	COG2203	Gaf domain
G8E00_RS11215	COG5001	Diguanylate cyclase
G8E00_RS11215	COG3706	GGDEF domain
G8E00_RS11215	COG4251	negative regulation of phosphorylation
G8E00_RS11225	COG0418	dihydroorotase activity
G8E00_RS11230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G8E00_RS11255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G8E00_RS11265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E00_RS11280	COG1301	dicarboxylic acid transport
G8E00_RS11310	COG1280	lysine exporter protein (LysE YggA)
G8E00_RS11315	COG1522	sequence-specific DNA binding
G8E00_RS11350	COG0019	diaminopimelate decarboxylase activity
G8E00_RS11360	COG1113	amino acid transport
G8E00_RS11365	COG1115	amino acid carrier protein
G8E00_RS11385	COG1794	racemase activity, acting on amino acids and derivatives
G8E00_RS11390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G8E00_RS11400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G8E00_RS11435	COG0772	Belongs to the SEDS family
G8E00_RS11440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G8E00_RS11465	COG0174	glutamine synthetase
G8E00_RS11480	COG0512	Glutamine amidotransferase of anthranilate synthase
G8E00_RS11485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G8E00_RS11490	COG0134	indole-3-glycerol-phosphate synthase activity
G8E00_RS11510	COG0302	gtp cyclohydrolase
G8E00_RS11520	COG3706	GGDEF domain
G8E00_RS11535	COG3739	integral membrane protein
G8E00_RS11540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G8E00_RS11550	COG1741	Belongs to the pirin family
G8E00_RS11560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G8E00_RS11595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G8E00_RS11605	COG0583	DNA-binding transcription factor activity
G8E00_RS11610	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G8E00_RS11620	COG0037	tRNA processing
G8E00_RS11625	COG0741	lytic transglycosylase activity
G8E00_RS11625	COG0739	heme binding
G8E00_RS11625	COG1196	nuclear chromosome segregation
G8E00_RS11630	COG0501	Belongs to the peptidase M48B family
G8E00_RS11645	COG2239	Acts as a magnesium transporter
G8E00_RS11650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G8E00_RS11655	COG0584	glycerophosphoryl diester phosphodiesterase
G8E00_RS11675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G8E00_RS11680	COG1597	lipid kinase activity
G8E00_RS11685	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G8E00_RS11690	COG0477	Major facilitator Superfamily
G8E00_RS11705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G8E00_RS11740	COG2304	oxidoreductase activity
G8E00_RS11745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G8E00_RS11750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G8E00_RS11775	COG0505	Belongs to the CarA family
G8E00_RS11780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G8E00_RS11790	COG0110	maltose O-acetyltransferase activity
G8E00_RS11835	COG2321	neutral zinc metallopeptidase
G8E00_RS11840	COG2354	Protein conserved in bacteria
G8E00_RS11850	COG1585	Membrane protein implicated in regulation of membrane protease activity
G8E00_RS11855	COG2268	Band 7 protein
G8E00_RS11870	COG3023	N-Acetylmuramoyl-L-alanine amidase
G8E00_RS11895	COG1253	flavin adenine dinucleotide binding
G8E00_RS11910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E00_RS11925	COG0805	protein transport
G8E00_RS11960	COG0004	ammonium transporteR
G8E00_RS11980	COG1752	Esterase of the alpha-beta hydrolase superfamily
G8E00_RS11995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G8E00_RS12000	COG0142	geranyltranstransferase activity
G8E00_RS12010	COG2828	Protein conserved in bacteria
G8E00_RS12015	COG1113	amino acid transport
G8E00_RS12045	COG0560	Phosphoserine phosphatase
G8E00_RS12055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G8E00_RS12065	COG1530	ribonuclease E activity
G8E00_RS12070	COG0424	maF-like protein
G8E00_RS12075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G8E00_RS12080	COG1792	Involved in formation and maintenance of cell shape
G8E00_RS12085	COG1077	Cell shape determining protein MreB Mrl
G8E00_RS12090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G8E00_RS12100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G8E00_RS12155	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G8E00_RS12170	COG1215	transferase activity, transferring glycosyl groups
G8E00_RS12175	COG0726	polysaccharide deacetylase
G8E00_RS12175	COG1649	PFAM Uncharacterised BCR, COG1649
G8E00_RS12190	COG4681	YaeQ
G8E00_RS12200	COG0523	cobalamin synthesis protein
G8E00_RS12215	COG1607	acyl-coa hydrolase
G8E00_RS12225	COG1752	Esterase of the alpha-beta hydrolase superfamily
G8E00_RS12230	COG0786	glutamate:sodium symporter activity
G8E00_RS12245	COG2814	Major facilitator Superfamily
G8E00_RS12250	COG1289	transmembrane transporter activity
G8E00_RS12260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G8E00_RS12320	COG2832	Protein of unknown function (DUF454)
G8E00_RS12345	COG2198	Histidine kinase
G8E00_RS12345	COG0643	Histidine kinase
G8E00_RS12345	COG0784	Response regulator, receiver
G8E00_RS12350	COG0840	transmembrane signaling receptor activity
G8E00_RS12375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E00_RS12385	COG0442	prolyl-tRNA aminoacylation
G8E00_RS12415	COG1045	serine acetyltransferase
G8E00_RS12430	COG0489	protein tyrosine kinase activity
G8E00_RS12455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G8E00_RS12455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G8E00_RS12465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G8E00_RS12515	COG2081	HI0933 family
G8E00_RS12530	COG0668	transmembrane transport
G8E00_RS12550	COG0583	DNA-binding transcription factor activity
G8E00_RS12560	COG1278	Cold shock
G8E00_RS12570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G8E00_RS12580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8E00_RS12585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G8E00_RS12590	COG0713	ATP synthesis coupled electron transport
G8E00_RS12600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8E00_RS12615	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G8E00_RS12650	COG0745	RESPONSE REGULATOR receiver
G8E00_RS12660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G8E00_RS12710	COG3152	Membrane
G8E00_RS12715	COG2314	TM2 domain
G8E00_RS12720	COG1652	LysM domain
G8E00_RS12730	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS12740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G8E00_RS12745	COG1399	metal-binding, possibly nucleic acid-binding protein
G8E00_RS12750	COG3101	peptidyl-lysine hydroxylation
G8E00_RS12755	COG0009	L-threonylcarbamoyladenylate synthase
G8E00_RS12765	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G8E00_RS12770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G8E00_RS12790	COG4106	trans-aconitate 2-methyltransferase activity
G8E00_RS12815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8E00_RS12825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G8E00_RS12835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G8E00_RS12845	COG1196	nuclear chromosome segregation
G8E00_RS12855	COG0730	response to heat
G8E00_RS12860	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G8E00_RS12860	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G8E00_RS12865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G8E00_RS12875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G8E00_RS12880	COG4137	Cytochrome C assembly protein
G8E00_RS12885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G8E00_RS12900	COG0494	nUDIX hydrolase
G8E00_RS12915	COG3422	double-strand break repair
G8E00_RS12920	COG2824	Alkylphosphonate utilization operon protein PhnA
G8E00_RS12930	COG0628	permease
G8E00_RS12945	COG0564	pseudouridine synthase activity
G8E00_RS12975	COG3293	Transposase
G8E00_RS13005	COG0354	folic acid binding
G8E00_RS13045	COG4772	TonB-dependent receptor
G8E00_RS13050	COG3659	wide pore channel activity
G8E00_RS13060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G8E00_RS13065	COG1011	Hydrolase
G8E00_RS13070	COG1970	mechanosensitive ion channel activity
G8E00_RS13080	COG2233	PERMEase
G8E00_RS13090	COG0833	amino acid
G8E00_RS13110	COG0183	Belongs to the thiolase family
G8E00_RS13130	COG0484	heat shock protein binding
G8E00_RS13140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E00_RS13185	COG4206	TonB-dependent receptor
G8E00_RS13190	COG2096	Adenosyltransferase
G8E00_RS13220	COG2315	Protein conserved in bacteria
G8E00_RS13225	COG0745	RESPONSE REGULATOR receiver
G8E00_RS13230	COG2205	protein histidine kinase activity
G8E00_RS13240	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS13245	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS13280	COG3307	-O-antigen
G8E00_RS13290	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G8E00_RS13315	COG1215	transferase activity, transferring glycosyl groups
G8E00_RS13340	COG1091	dTDP-4-dehydrorhamnose reductase activity
G8E00_RS13375	COG0438	transferase activity, transferring glycosyl groups
G8E00_RS13385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G8E00_RS13400	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G8E00_RS13405	COG0784	Response regulator, receiver
G8E00_RS13405	COG2205	protein histidine kinase activity
G8E00_RS13405	COG5002	protein histidine kinase activity
G8E00_RS13415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G8E00_RS13445	COG1862	Preprotein translocase
G8E00_RS13470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E00_RS13490	COG1426	Protein conserved in bacteria
G8E00_RS13540	COG0440	acetolactate synthase activity
G8E00_RS13545	COG0028	Belongs to the TPP enzyme family
G8E00_RS13570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E00_RS13575	COG0577	efflux transmembrane transporter activity
G8E00_RS13575	COG1136	(ABC) transporter
G8E00_RS13590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8E00_RS13595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8E00_RS13605	COG3501	Rhs element vgr protein
G8E00_RS13620	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G8E00_RS13625	COG1162	GTPase activity
G8E00_RS13635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G8E00_RS13650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G8E00_RS13655	COG2003	Belongs to the UPF0758 family
G8E00_RS13660	COG3781	membrane
G8E00_RS13675	COG2350	Protein conserved in bacteria
G8E00_RS13690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G8E00_RS13710	COG1607	acyl-coa hydrolase
G8E00_RS13775	COG1183	phosphatidylcholine synthase activity
G8E00_RS13780	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G8E00_RS13815	COG0739	heme binding
G8E00_RS13815	COG1196	nuclear chromosome segregation
G8E00_RS13815	COG0741	lytic transglycosylase activity
G8E00_RS13820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G8E00_RS13825	COG1702	phosphate starvation-inducible protein PhoH
G8E00_RS13835	COG0668	transmembrane transport
G8E00_RS13865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E00_RS13880	COG1295	ribonuclease BN
G8E00_RS13885	COG0179	Fumarylacetoacetate (FAA) hydrolase
G8E00_RS13930	COG0557	exoribonuclease II activity
G8E00_RS13940	COG0339	signal peptide processing
G8E00_RS13945	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G8E00_RS13975	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G8E00_RS13980	COG1960	acyl-CoA dehydrogenase activity
G8E00_RS13985	COG0546	phosphoglycolate phosphatase activity
G8E00_RS13995	COG1530	ribonuclease E activity
G8E00_RS14000	COG0318	PFAM AMP-dependent synthetase and ligase
G8E00_RS14025	COG1983	PspC domain protein
G8E00_RS14045	COG0471	metal ion transport
G8E00_RS14070	COG0751	glycine-tRNA ligase activity
G8E00_RS14080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G8E00_RS14110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G8E00_RS14160	COG0628	permease
G8E00_RS14165	COG2032	superoxide dismutase activity
G8E00_RS14170	COG2814	Major facilitator Superfamily
G8E00_RS14215	COG0277	FAD linked oxidase domain protein
G8E00_RS14220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G8E00_RS14225	COG5006	permease, DMT superfamily
G8E00_RS14245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G8E00_RS14250	COG5380	lipid catabolic process
G8E00_RS14255	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G8E00_RS14260	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G8E00_RS14265	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G8E00_RS14270	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G8E00_RS14275	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G8E00_RS14280	COG0335	large ribosomal subunit rRNA binding
G8E00_RS14290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G8E00_RS14295	COG0228	four-way junction DNA binding
G8E00_RS14305	COG4969	Belongs to the N-Me-Phe pilin family
G8E00_RS14330	COG4969	Belongs to the N-Me-Phe pilin family
G8E00_RS14335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G8E00_RS14340	COG0194	GDP metabolic process
G8E00_RS14345	COG1758	RNA polymerase activity
G8E00_RS14350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G8E00_RS14370	COG3307	-O-antigen
G8E00_RS14375	COG3307	-O-antigen
G8E00_RS14390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G8E00_RS14395	COG1704	LemA family
G8E00_RS14405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G8E00_RS14410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G8E00_RS14415	COG0195	Participates in both transcription termination and antitermination
G8E00_RS14420	COG0779	Required for maturation of 30S ribosomal subunits
G8E00_RS14470	COG0237	dephospho-CoA kinase activity
G8E00_RS14480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8E00_RS14490	COG0497	DNA recombination
G8E00_RS14505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G8E00_RS14535	COG1132	(ABC) transporter
G8E00_RS14550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G8E00_RS14585	COG1024	Enoyl-CoA hydratase
G8E00_RS14585	COG1250	3-hydroxyacyl-CoA dehydrogenase
G8E00_RS14590	COG0183	Belongs to the thiolase family
G8E00_RS14595	COG3706	GGDEF domain
G8E00_RS14615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G8E00_RS14635	COG0326	Molecular chaperone. Has ATPase activity
G8E00_RS14650	COG2056	Na+-H+ antiporter family
G8E00_RS14680	COG0085	RNA polymerase activity
G8E00_RS14695	COG0081	regulation of translation
G8E00_RS14710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G8E00_RS14750	COG0546	phosphoglycolate phosphatase activity
G8E00_RS14800	COG0181	hydroxymethylbilane synthase activity
G8E00_RS14810	COG3275	phosphorelay sensor kinase activity
G8E00_RS14830	COG1538	Outer membrane efflux protein
G8E00_RS14850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G8E00_RS14855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G8E00_RS14865	COG0772	Belongs to the SEDS family
G8E00_RS14895	COG4974	Belongs to the 'phage' integrase family
G8E00_RS14900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G8E00_RS14910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G8E00_RS14920	COG1686	Belongs to the peptidase S11 family
G8E00_RS14925	COG2197	response regulator
G8E00_RS14940	COG0793	Belongs to the peptidase S41A family
G8E00_RS14945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G8E00_RS14950	COG0795	lipopolysaccharide-transporting ATPase activity
G8E00_RS14955	COG0795	lipopolysaccharide-transporting ATPase activity
G8E00_RS14975	COG0586	Pfam SNARE associated Golgi protein
G8E00_RS14990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G8E00_RS14990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G8E00_RS14995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G8E00_RS15000	COG0004	ammonium transporteR
G8E00_RS15005	COG0347	Belongs to the P(II) protein family
G8E00_RS15025	COG0659	secondary active sulfate transmembrane transporter activity
G8E00_RS15030	COG0589	response to stress
G8E00_RS15040	COG0640	Transcriptional regulator
G8E00_RS15050	COG0798	PFAM Bile acid sodium symporter
G8E00_RS15055	COG0431	NADPH-dependent FMN reductase
G8E00_RS15060	COG0492	ferredoxin-NADP+ reductase activity
G8E00_RS15095	COG0606	chelatase, subunit chli
G8E00_RS15115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G8E00_RS15130	COG0318	PFAM AMP-dependent synthetase and ligase
G8E00_RS15140	COG0477	Major facilitator Superfamily
G8E00_RS15145	COG2860	membrane
G8E00_RS15155	COG1253	flavin adenine dinucleotide binding
G8E00_RS15165	COG2814	Major facilitator Superfamily
G8E00_RS15175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G8E00_RS15180	COG0477	Major facilitator Superfamily
G8E00_RS15210	COG2814	Major facilitator Superfamily
G8E00_RS15275	COG0758	DNA mediated transformation
G8E00_RS15285	COG0697	spore germination
G8E00_RS15295	COG0386	Belongs to the glutathione peroxidase family
G8E00_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
G8E00_RS15355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G8E00_RS15405	COG1121	(ABC) transporter
G8E00_RS15410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G8E00_RS15415	COG0668	transmembrane transport
G8E00_RS15420	COG1280	lysine exporter protein (LysE YggA)
G8E00_RS15430	COG2837	iron assimilation
G8E00_RS15455	COG3501	Rhs element vgr protein
G8E00_RS15460	COG0281	malic enzyme
G8E00_RS15490	COG3150	esterase
G8E00_RS15515	COG2918	glutathione biosynthetic process
G8E00_RS15530	COG2733	membrane
G8E00_RS15540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G8E00_RS15540	COG2755	lipolytic protein G-D-S-L family
G8E00_RS15545	COG0436	Aminotransferase
G8E00_RS15550	COG0534	Mate efflux family protein
G8E00_RS15555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E00_RS15570	COG3829	transcription factor binding
G8E00_RS15575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E00_RS15585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E00_RS15590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E00_RS15670	COG0753	catalase activity
G8E00_RS15690	COG0560	Phosphoserine phosphatase
G8E00_RS15690	COG3830	Belongs to the UPF0237 family
G8E00_RS15715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G8E00_RS15720	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G8E00_RS15730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G8E00_RS15765	COG1002	Type II restriction enzyme, methylase subunits
G8E00_RS15770	COG1061	Type III restriction enzyme res subunit
G8E00_RS15780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G8E00_RS15795	COG0730	response to heat
G8E00_RS15815	COG1683	Conserved Protein
G8E00_RS15825	COG0385	Bile acid
G8E00_RS15830	COG1335	isochorismatase
G8E00_RS15835	COG2814	Major facilitator Superfamily
G8E00_RS15840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G8E00_RS15860	COG0584	glycerophosphoryl diester phosphodiesterase
G8E00_RS15870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G8E00_RS15875	COG2133	pyrroloquinoline quinone binding
G8E00_RS15880	COG2983	Belongs to the UPF0260 family
G8E00_RS15885	COG5487	UPF0391 membrane protein
G8E00_RS15900	COG1194	a g-specific adenine glycosylase
G8E00_RS15915	COG2818	Glycosylase
G8E00_RS15930	COG2814	Major facilitator Superfamily
G8E00_RS15955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G8E00_RS15955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G8E00_RS15960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E00_RS15965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E00_RS15970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E00_RS15975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E00_RS15980	COG1116	anion transmembrane transporter activity
G8E00_RS15985	COG1309	transcriptional regulator
G8E00_RS15995	COG0196	riboflavin kinase activity
G8E00_RS16000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G8E00_RS16010	COG1047	Peptidyl-prolyl cis-trans
G8E00_RS16170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G8E00_RS16190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G8E00_RS16200	COG0789	Transcriptional regulator
G8E00_RS16215	COG0488	(ABC) transporter
G8E00_RS16220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G8E00_RS16225	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G8E00_RS16245	COG0596	Alpha beta hydrolase
G8E00_RS16275	COG0187	DNA topoisomerase II activity
G8E00_RS16285	COG0592	DNA-directed DNA polymerase activity