locus-tag	class	description
C3F22_RS00010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3F22_RS00020	COG0237	dephospho-CoA kinase activity
C3F22_RS00040	COG0149	triose-phosphate isomerase activity
C3F22_RS00075	COG0779	Required for maturation of 30S ribosomal subunits
C3F22_RS00080	COG0195	Participates in both transcription termination and antitermination
C3F22_RS00090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C3F22_RS00095	COG1320	monovalent cation:proton antiporter activity
C3F22_RS00100	COG2212	antiporter activity
C3F22_RS00105	COG1863	multisubunit Na H antiporter MnhE subunit
C3F22_RS00110	COG0651	ATP synthesis coupled electron transport
C3F22_RS00115	COG1006	Multisubunit Na H antiporter MnhC subunit
C3F22_RS00120	COG2111	Na H antiporter
C3F22_RS00120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3F22_RS00135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C3F22_RS00140	COG4221	oxidoreductase activity
C3F22_RS00150	COG0488	(ABC) transporter
C3F22_RS00190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_RS00200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_RS00220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C3F22_RS00225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3F22_RS00230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C3F22_RS00235	COG2226	methyltransferase
C3F22_RS00285	COG0067	glutamate synthase
C3F22_RS00285	COG0069	glutamate synthase activity
C3F22_RS00285	COG0070	glutamate synthase
C3F22_RS00290	COG0493	'glutamate synthase
C3F22_RS00295	COG1704	LemA family
C3F22_RS00350	COG3620	sequence-specific DNA binding
C3F22_RS00430	COG3307	-O-antigen
C3F22_RS00450	COG0675	Transposase, IS605 OrfB family
C3F22_RS00455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3F22_RS00460	COG1758	RNA polymerase activity
C3F22_RS00465	COG0194	GDP metabolic process
C3F22_RS00510	COG0228	four-way junction DNA binding
C3F22_RS00515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C3F22_RS00525	COG0335	large ribosomal subunit rRNA binding
C3F22_RS00535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C3F22_RS00540	COG5380	lipid catabolic process
C3F22_RS00545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C3F22_RS00580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3F22_RS00585	COG0277	FAD linked oxidase domain protein
C3F22_RS00610	COG2814	Major facilitator Superfamily
C3F22_RS00615	COG1289	transmembrane transporter activity
C3F22_RS00625	COG0628	permease
C3F22_RS00660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C3F22_RS00665	COG0254	rRNA binding
C3F22_RS00670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C3F22_RS00680	COG0534	Mate efflux family protein
C3F22_RS00690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3F22_RS00700	COG1278	Cold shock
C3F22_RS00705	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS00720	COG0408	coproporphyrinogen oxidase activity
C3F22_RS00725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3F22_RS00735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C3F22_RS00745	COG0513	Belongs to the DEAD box helicase family
C3F22_RS00750	COG1127	ABC transporter
C3F22_RS00755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C3F22_RS00760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C3F22_RS00765	COG2854	intermembrane phospholipid transfer
C3F22_RS00775	COG0598	Magnesium transport protein CorA
C3F22_RS00790	COG1040	competence protein
C3F22_RS00795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C3F22_RS00810	COG2937	Belongs to the GPAT DAPAT family
C3F22_RS00815	COG1946	Acyl-CoA thioesterase
C3F22_RS00820	COG1301	dicarboxylic acid transport
C3F22_RS00855	COG1959	2 iron, 2 sulfur cluster binding
C3F22_RS00865	COG0433	COG0433 Predicted ATPase
C3F22_RS00870	COG0626	cystathionine gamma-synthase activity
C3F22_RS00885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C3F22_RS00890	COG0088	Forms part of the polypeptide exit tunnel
C3F22_RS00905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C3F22_RS00950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C3F22_RS00955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C3F22_RS00960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C3F22_RS00970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C3F22_RS00995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C3F22_RS01005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C3F22_RS01010	COG0202	RNA polymerase activity
C3F22_RS01015	COG0203	ribosomal protein L17
C3F22_RS01020	COG2072	flavoprotein involved in K transport
C3F22_RS01025	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS01030	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C3F22_RS01055	COG0697	spore germination
C3F22_RS01065	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C3F22_RS01070	COG0339	signal peptide processing
C3F22_RS01080	COG0557	exoribonuclease II activity
C3F22_RS01120	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3F22_RS01130	COG1295	ribonuclease BN
C3F22_RS01195	COG1702	phosphate starvation-inducible protein PhoH
C3F22_RS01200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3F22_RS01205	COG1196	nuclear chromosome segregation
C3F22_RS01205	COG0741	lytic transglycosylase activity
C3F22_RS01205	COG0739	heme binding
C3F22_RS01245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C3F22_RS01250	COG1183	phosphatidylcholine synthase activity
C3F22_RS01320	COG1607	acyl-coa hydrolase
C3F22_RS01350	COG2350	Protein conserved in bacteria
C3F22_RS01365	COG3781	membrane
C3F22_RS01370	COG2003	Belongs to the UPF0758 family
C3F22_RS01375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3F22_RS01385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3F22_RS01395	COG2814	Major facilitator Superfamily
C3F22_RS01425	COG3622	Belongs to the hyi family
C3F22_RS01430	COG2084	Dehydrogenase
C3F22_RS01435	COG1024	Enoyl-CoA hydratase
C3F22_RS01440	COG0784	Response regulator, receiver
C3F22_RS01440	COG2205	protein histidine kinase activity
C3F22_RS01440	COG5002	protein histidine kinase activity
C3F22_RS01445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3F22_RS01460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3F22_RS01475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3F22_RS01485	COG1862	Preprotein translocase
C3F22_RS01500	COG1704	LemA family
C3F22_RS01510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C3F22_RS01520	COG3293	Transposase
C3F22_RS01525	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_RS01550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C3F22_RS01575	COG0625	glutathione transferase activity
C3F22_RS01585	COG1238	metal cluster binding
C3F22_RS01610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C3F22_RS01615	COG0072	phenylalanine-tRNA ligase activity
C3F22_RS01640	COG0248	Ppx GppA phosphatase
C3F22_RS01650	COG0037	tRNA processing
C3F22_RS01695	COG1764	response to oxidative stress
C3F22_RS01700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3F22_RS01775	COG2969	positive regulation of protein catabolic process
C3F22_RS01780	COG0625	glutathione transferase activity
C3F22_RS01785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C3F22_RS01790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C3F22_RS01795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C3F22_RS01800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C3F22_RS01805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C3F22_RS01835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3F22_RS01845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3F22_RS01850	COG1408	metallophosphoesterase
C3F22_RS01860	COG0477	Major facilitator Superfamily
C3F22_RS01865	COG1272	protein, Hemolysin III
C3F22_RS01885	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3F22_RS01885	COG1024	Enoyl-CoA hydratase
C3F22_RS01890	COG0183	Belongs to the thiolase family
C3F22_RS01895	COG2207	Transcriptional regulator
C3F22_RS01900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C3F22_RS01905	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_RS01920	COG0183	Belongs to the thiolase family
C3F22_RS01940	COG0833	amino acid
C3F22_RS01950	COG2233	PERMEase
C3F22_RS01955	COG1217	gtp-binding protein TYPA
C3F22_RS01980	COG1902	pentaerythritol trinitrate reductase activity
C3F22_RS01985	COG0679	Auxin Efflux Carrier
C3F22_RS01995	COG0354	folic acid binding
C3F22_RS02000	COG2132	Multicopper oxidase
C3F22_RS02005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C3F22_RS02050	COG0564	pseudouridine synthase activity
C3F22_RS02070	COG2824	Alkylphosphonate utilization operon protein PhnA
C3F22_RS02085	COG0351	phosphomethylpyrimidine kinase
C3F22_RS02085	COG0352	thiamine-phosphate diphosphorylase activity
C3F22_RS02085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3F22_RS02110	COG3152	Membrane
C3F22_RS02150	COG2223	nitrite transmembrane transporter activity
C3F22_RS02205	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS02215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3F22_RS02230	COG0745	RESPONSE REGULATOR receiver
C3F22_RS02235	COG2205	protein histidine kinase activity
C3F22_RS02245	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3F22_RS02265	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C3F22_RS02280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3F22_RS02285	COG0839	Belongs to the complex I subunit 6 family
C3F22_RS02290	COG0713	ATP synthesis coupled electron transport
C3F22_RS02295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3F22_RS02300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3F22_RS02335	COG0583	DNA-binding transcription factor activity
C3F22_RS02355	COG0668	transmembrane transport
C3F22_RS02360	COG2081	HI0933 family
C3F22_RS02370	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C3F22_RS02385	COG0004	ammonium transporteR
C3F22_RS02390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3F22_RS02430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3F22_RS02430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3F22_RS02440	COG0489	protein tyrosine kinase activity
C3F22_RS02455	COG2358	TRAP transporter, solute receptor (TAXI family
C3F22_RS02530	COG0840	transmembrane signaling receptor activity
C3F22_RS02560	COG2832	Protein of unknown function (DUF454)
C3F22_RS02620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C3F22_RS02630	COG1289	transmembrane transporter activity
C3F22_RS02635	COG2814	Major facilitator Superfamily
C3F22_RS02645	COG0786	glutamate:sodium symporter activity
C3F22_RS02650	COG1115	amino acid carrier protein
C3F22_RS02660	COG2059	Chromate
C3F22_RS02665	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3F22_RS02670	COG1607	acyl-coa hydrolase
C3F22_RS02685	COG0583	DNA-binding transcription factor activity
C3F22_RS02690	COG0625	glutathione transferase activity
C3F22_RS02705	COG0523	cobalamin synthesis protein
C3F22_RS02715	COG1285	pathogenesis
C3F22_RS02725	COG2199	diguanylate cyclase activity
C3F22_RS02725	COG2203	Gaf domain
C3F22_RS02765	COG0393	Putative heavy-metal-binding
C3F22_RS02770	COG0393	Putative heavy-metal-binding
C3F22_RS02775	COG1538	Outer membrane efflux protein
C3F22_RS02785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_RS02790	COG0671	phosphoesterase, PA-phosphatase related
C3F22_RS02805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C3F22_RS02815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C3F22_RS02830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C3F22_RS02835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C3F22_RS02835	COG1648	precorrin-2 dehydrogenase activity
C3F22_RS02840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C3F22_RS02845	COG4372	Transposase
C3F22_RS02855	COG2963	transposase activity
C3F22_RS02865	COG0531	amino acid
C3F22_RS02885	COG0321	lipoyl(octanoyl) transferase activity
C3F22_RS02895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3F22_RS02915	COG0586	Pfam SNARE associated Golgi protein
C3F22_RS02940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3F22_RS02970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C3F22_RS03000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C3F22_RS03010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C3F22_RS03015	COG0358	DNA primase activity
C3F22_RS03025	COG0564	pseudouridine synthase activity
C3F22_RS03050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3F22_RS03070	COG0110	maltose O-acetyltransferase activity
C3F22_RS03075	COG0251	oxidation-reduction process
C3F22_RS03080	COG1309	transcriptional regulator
C3F22_RS03090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C3F22_RS03095	COG0505	Belongs to the CarA family
C3F22_RS03120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C3F22_RS03125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3F22_RS03135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C3F22_RS03170	COG1253	flavin adenine dinucleotide binding
C3F22_RS03190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3F22_RS03200	COG2239	Acts as a magnesium transporter
C3F22_RS03210	COG0501	Belongs to the peptidase M48B family
C3F22_RS03215	COG0741	lytic transglycosylase activity
C3F22_RS03215	COG0739	heme binding
C3F22_RS03215	COG1196	nuclear chromosome segregation
C3F22_RS03220	COG0037	tRNA processing
C3F22_RS03230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C3F22_RS03235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C3F22_RS03250	COG0583	DNA-binding transcription factor activity
C3F22_RS03255	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS03265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C3F22_RS03275	COG4372	Transposase
C3F22_RS03315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3F22_RS03320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C3F22_RS03325	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C3F22_RS03355	COG1115	amino acid carrier protein
C3F22_RS03360	COG1113	amino acid transport
C3F22_RS03385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C3F22_RS03395	COG1522	sequence-specific DNA binding
C3F22_RS03400	COG1280	lysine exporter protein (LysE YggA)
C3F22_RS03440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_RS03460	COG1671	Belongs to the UPF0178 family
C3F22_RS03480	COG1136	(ABC) transporter
C3F22_RS03485	COG0658	competence protein
C3F22_RS03485	COG2333	competence protein COMEC
C3F22_RS03500	COG2267	carboxylic ester hydrolase activity
C3F22_RS03505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C3F22_RS03510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C3F22_RS03515	COG0628	permease
C3F22_RS03520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C3F22_RS03550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3F22_RS03575	COG0823	Involved in the tonB-independent uptake of proteins
C3F22_RS03595	COG0824	Thioesterase
C3F22_RS03600	COG1473	amidohydrolase
C3F22_RS03605	COG2255	four-way junction helicase activity
C3F22_RS03625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C3F22_RS03625	COG0047	phosphoribosylformylglycinamidine synthase activity
C3F22_RS03635	COG0583	DNA-binding transcription factor activity
C3F22_RS03685	COG0778	Nitroreductase
C3F22_RS03690	COG1024	Enoyl-CoA hydratase
C3F22_RS03695	COG1056	cytidyltransferase-related domain
C3F22_RS03695	COG1051	belongs to the nudix hydrolase family
C3F22_RS03700	COG2353	YceI-like domain
C3F22_RS03705	COG0583	DNA-binding transcription factor activity
C3F22_RS03710	COG1279	arginine transmembrane transporter activity
C3F22_RS03715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3F22_RS03725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C3F22_RS03730	COG0602	queuosine metabolic process
C3F22_RS03750	COG0583	DNA-binding transcription factor activity
C3F22_RS03755	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C3F22_RS03760	COG4208	sulfate ABC transporter
C3F22_RS03765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C3F22_RS03775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_RS03780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_RS03790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C3F22_RS03815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3F22_RS03840	COG0571	ribonuclease III activity
C3F22_RS03845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C3F22_RS03855	COG1381	Involved in DNA repair and RecF pathway recombination
C3F22_RS03860	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C3F22_RS03890	COG0534	Mate efflux family protein
C3F22_RS03895	COG0436	Aminotransferase
C3F22_RS03905	COG0052	Belongs to the universal ribosomal protein uS2 family
C3F22_RS03930	COG2951	lytic endotransglycosylase activity
C3F22_RS03945	COG0842	Transport permease protein
C3F22_RS03950	COG1131	(ABC) transporter
C3F22_RS04010	COG2862	Uncharacterized protein family, UPF0114
C3F22_RS04030	COG3634	alkyl hydroperoxide reductase activity
C3F22_RS04035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3F22_RS04040	COG0826	peptidase U32
C3F22_RS04075	COG1720	tRNA m6t6A37 methyltransferase activity
C3F22_RS04100	COG3293	Transposase
C3F22_RS04115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C3F22_RS04130	COG0642	Histidine kinase
C3F22_RS04145	COG0494	nUDIX hydrolase
C3F22_RS04155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3F22_RS04160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C3F22_RS04165	COG3139	Protein of unknown function (DUF1315)
C3F22_RS04175	COG1301	dicarboxylic acid transport
C3F22_RS04185	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS04190	COG0693	protein deglycase activity
C3F22_RS04200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C3F22_RS04205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C3F22_RS04235	COG2252	PERMEase
C3F22_RS04240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C3F22_RS04255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C3F22_RS04265	COG0527	aspartate kinase activity
C3F22_RS04270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3F22_RS04280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3F22_RS04310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C3F22_RS04335	COG1252	NADH dehydrogenase
C3F22_RS04340	COG1686	Belongs to the peptidase S11 family
C3F22_RS04355	COG2351	hydroxyisourate hydrolase activity
C3F22_RS04375	COG1187	pseudouridine synthase activity
C3F22_RS04400	COG0436	Aminotransferase
C3F22_RS04405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_RS04410	COG0386	Belongs to the glutathione peroxidase family
C3F22_RS04420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C3F22_RS04440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C3F22_RS04450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3F22_RS04455	COG0012	GTP binding
C3F22_RS04460	COG2011	ABC-type metal ion transport system permease component
C3F22_RS04465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C3F22_RS04470	COG1464	Belongs to the NlpA lipoprotein family
C3F22_RS04570	COG0804	urea catabolic process
C3F22_RS04590	COG2351	hydroxyisourate hydrolase activity
C3F22_RS04595	COG2233	PERMEase
C3F22_RS04610	COG4266	Belongs to the allantoicase family
C3F22_RS04615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_RS04620	COG0583	DNA-binding transcription factor activity
C3F22_RS04650	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C3F22_RS04675	COG1401	restriction endodeoxyribonuclease activity
C3F22_RS04675	COG1401	restriction endodeoxyribonuclease activity
C3F22_RS04685	COG0210	DNA helicase
C3F22_RS04690	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C3F22_RS04695	COG1484	DNA-dependent DNA replication
C3F22_RS04700	COG4584	PFAM Integrase catalytic
C3F22_RS04700	COG2390	Transcriptional regulator
C3F22_RS04785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C3F22_RS04785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C3F22_RS04790	COG1254	Belongs to the acylphosphatase family
C3F22_RS04825	COG3634	alkyl hydroperoxide reductase activity
C3F22_RS04850	COG1643	Atp-dependent helicase
C3F22_RS04870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3F22_RS04875	COG2707	UPF0756 membrane protein
C3F22_RS04900	COG0802	atpase or kinase
C3F22_RS04905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C3F22_RS04915	COG1923	regulation of RNA biosynthetic process
C3F22_RS04920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3F22_RS04930	COG3178	'Phosphotransferase
C3F22_RS04935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C3F22_RS04945	COG1192	Involved in chromosome partitioning
C3F22_RS04950	COG1475	DNA binding
C3F22_RS04955	COG0811	peptide transport
C3F22_RS04965	COG1132	(ABC) transporter
C3F22_RS04970	COG1663	tetraacyldisaccharide 4'-kinase activity
C3F22_RS04990	COG0084	hydrolase, TatD family'
C3F22_RS04995	COG1309	transcriptional regulator
C3F22_RS05025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C3F22_RS05045	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C3F22_RS05055	COG0776	regulation of translation
C3F22_RS05075	COG2431	L-lysine efflux transmembrane transporter activity
C3F22_RS05090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C3F22_RS05095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C3F22_RS05130	COG1253	flavin adenine dinucleotide binding
C3F22_RS05150	COG0308	aminopeptidase N
C3F22_RS05160	COG0589	response to stress
C3F22_RS05165	COG0589	response to stress
C3F22_RS05180	COG3135	benzoate transporter
C3F22_RS05190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C3F22_RS05205	COG0183	Belongs to the thiolase family
C3F22_RS05230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C3F22_RS05235	COG0824	Thioesterase
C3F22_RS05240	COG1454	alcohol dehydrogenase
C3F22_RS05245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C3F22_RS05265	COG0069	glutamate synthase activity
C3F22_RS05275	COG2308	Evidence 4 Homologs of previously reported genes of
C3F22_RS05285	COG1305	Transglutaminase-like
C3F22_RS05300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3F22_RS05305	COG0305	Participates in initiation and elongation during chromosome replication
C3F22_RS05320	COG0360	Binds together with S18 to 16S ribosomal RNA
C3F22_RS05335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C3F22_RS05340	COG1845	cytochrome c oxidase, subunit III
C3F22_RS05345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C3F22_RS05350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C3F22_RS05380	COG2963	transposase activity
C3F22_RS05390	COG4372	Transposase
C3F22_RS05395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3F22_RS05410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C3F22_RS05415	COG2890	protein-(glutamine-N5) methyltransferase activity
C3F22_RS05420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3F22_RS05425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3F22_RS05450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3F22_RS05465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3F22_RS05475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C3F22_RS05495	COG0477	Major facilitator Superfamily
C3F22_RS05500	COG0729	surface antigen
C3F22_RS05515	COG1570	exodeoxyribonuclease VII activity
C3F22_RS05555	COG0786	glutamate:sodium symporter activity
C3F22_RS05580	COG0024	Methionine aminopeptidase
C3F22_RS05585	COG0583	DNA-binding transcription factor activity
C3F22_RS05590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C3F22_RS05605	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3F22_RS05605	COG1902	pentaerythritol trinitrate reductase activity
C3F22_RS05640	COG0148	phosphopyruvate hydratase activity
C3F22_RS05655	COG0772	Belongs to the SEDS family
C3F22_RS05670	COG4890	Cyd operon protein YbgT
C3F22_RS05675	COG1294	oxidase, subunit
C3F22_RS05725	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C3F22_RS05745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3F22_RS05755	COG0133	tryptophan synthase activity
C3F22_RS05760	COG0517	IMP dehydrogenase activity
C3F22_RS05760	COG0516	GMP reductase activity
C3F22_RS05795	COG0612	Peptidase, M16
C3F22_RS05800	COG0552	protein localization to endoplasmic reticulum
C3F22_RS05855	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS05940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C3F22_RS05945	COG0730	response to heat
C3F22_RS05950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3F22_RS05955	COG2207	Transcriptional regulator
C3F22_RS05960	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3F22_RS05965	COG3293	Transposase
C3F22_RS05970	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS05985	COG1476	TRANSCRIPTIONal
C3F22_RS06010	COG1271	oxidase subunit
C3F22_RS06015	COG1294	oxidase, subunit
C3F22_RS06025	COG1525	nuclease
C3F22_RS06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3F22_RS06090	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C3F22_RS06100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C3F22_RS06115	COG2814	Major facilitator Superfamily
C3F22_RS06120	COG0509	glycine decarboxylation via glycine cleavage system
C3F22_RS06130	COG1132	(ABC) transporter
C3F22_RS06140	COG0668	transmembrane transport
C3F22_RS06155	COG3122	Protein conserved in bacteria
C3F22_RS06170	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS06180	COG0640	Transcriptional regulator
C3F22_RS06185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3F22_RS06195	COG0789	Transcriptional regulator
C3F22_RS06210	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS06220	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C3F22_RS06225	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS06240	COG0183	Belongs to the thiolase family
C3F22_RS06260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3F22_RS06265	COG0183	Belongs to the thiolase family
C3F22_RS06270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3F22_RS06275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C3F22_RS06280	COG3135	benzoate transporter
C3F22_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS06290	COG0543	2 iron, 2 sulfur cluster binding
C3F22_RS06290	COG0633	Ferredoxin
C3F22_RS06295	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C3F22_RS06300	COG4638	Rieske (2fe-2S)
C3F22_RS06310	COG4829	muconolactone delta-isomerase
C3F22_RS06315	COG4948	Mandelate Racemase Muconate Lactonizing
C3F22_RS06320	COG0583	DNA-binding transcription factor activity
C3F22_RS06325	COG2814	Major facilitator Superfamily
C3F22_RS06335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3F22_RS06345	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_RS06365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C3F22_RS06395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3F22_RS06400	COG1309	transcriptional regulator
C3F22_RS06430	COG1944	ATP diphosphatase activity
C3F22_RS06440	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS06445	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS06450	COG2814	Major facilitator Superfamily
C3F22_RS06460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3F22_RS06470	COG2814	Major facilitator Superfamily
C3F22_RS06480	COG2814	Major facilitator Superfamily
C3F22_RS06490	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3F22_RS06495	COG0183	Belongs to the thiolase family
C3F22_RS06505	COG0235	Class ii aldolase
C3F22_RS06510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3F22_RS06515	COG1024	Enoyl-CoA hydratase
C3F22_RS06525	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS06530	COG2267	carboxylic ester hydrolase activity
C3F22_RS06545	COG2814	Major facilitator Superfamily
C3F22_RS06550	COG2814	Major facilitator Superfamily
C3F22_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS06570	COG1136	(ABC) transporter
C3F22_RS06575	COG0640	Transcriptional regulator
C3F22_RS06605	COG2132	Multicopper oxidase
C3F22_RS06635	COG4773	Receptor
C3F22_RS06640	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
C3F22_RS06645	COG2116	formate transmembrane transporter activity
C3F22_RS06650	COG0515	serine threonine protein kinase
C3F22_RS06710	COG1289	transmembrane transporter activity
C3F22_RS06750	COG2801	Transposase and inactivated derivatives
C3F22_RS06755	COG4772	TonB-dependent receptor
C3F22_RS06790	COG1079	Belongs to the binding-protein-dependent transport system permease family
C3F22_RS06800	COG3845	ABC transporter
C3F22_RS06825	COG0583	DNA-binding transcription factor activity
C3F22_RS06835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_RS06840	COG4266	Belongs to the allantoicase family
C3F22_RS06855	COG2233	PERMEase
C3F22_RS06860	COG2351	hydroxyisourate hydrolase activity
C3F22_RS06890	COG0804	urea catabolic process
C3F22_RS06905	COG0829	nickel cation binding
C3F22_RS06920	COG0830	nickel cation binding
C3F22_RS07055	COG0596	Alpha beta hydrolase
C3F22_RS07090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3F22_RS07130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C3F22_RS07145	COG0439	Biotin carboxylase
C3F22_RS07155	COG3706	GGDEF domain
C3F22_RS07165	COG2814	Major facilitator Superfamily
C3F22_RS07195	COG5499	transcription regulator containing HTH domain
C3F22_RS07200	COG4680	protein conserved in bacteria
C3F22_RS07220	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS07230	COG1058	Belongs to the CinA family
C3F22_RS07230	COG1546	Belongs to the CinA family
C3F22_RS07240	COG0372	Belongs to the citrate synthase family
C3F22_RS07255	COG3293	Transposase
C3F22_RS07275	COG0542	response to heat
C3F22_RS07280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C3F22_RS07300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C3F22_RS07305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C3F22_RS07310	COG0569	domain protein
C3F22_RS07315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3F22_RS07335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3F22_RS07345	COG1585	Membrane protein implicated in regulation of membrane protease activity
C3F22_RS07365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3F22_RS07385	COG1959	2 iron, 2 sulfur cluster binding
C3F22_RS07395	COG0822	iron-sulfur transferase activity
C3F22_RS07400	COG0316	Belongs to the HesB IscA family
C3F22_RS07430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C3F22_RS07440	COG1027	Aspartate ammonia-lyase
C3F22_RS07450	COG1522	sequence-specific DNA binding
C3F22_RS07465	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C3F22_RS07465	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C3F22_RS07465	COG0506	proline dehydrogenase activity
C3F22_RS07485	COG3781	membrane
C3F22_RS07490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C3F22_RS07530	COG0697	spore germination
C3F22_RS07555	COG0424	maF-like protein
C3F22_RS07560	COG2850	peptidyl-arginine hydroxylation
C3F22_RS07570	COG2197	response regulator
C3F22_RS07580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C3F22_RS07585	COG0702	epimerase
C3F22_RS07590	COG0268	Binds directly to 16S ribosomal RNA
C3F22_RS07605	COG1011	Hydrolase
C3F22_RS07610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C3F22_RS07620	COG2137	regulation of response to DNA damage stimulus
C3F22_RS07640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3F22_RS07645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C3F22_RS07660	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3F22_RS07675	COG0575	Belongs to the CDS family
C3F22_RS07680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C3F22_RS07700	COG3852	Histidine kinase
C3F22_RS07715	COG0445	tRNA wobble uridine modification
C3F22_RS07750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C3F22_RS07755	COG0138	bifunctional purine biosynthesis protein purh
C3F22_RS07775	COG1464	Belongs to the NlpA lipoprotein family
C3F22_RS07780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C3F22_RS07785	COG2011	ABC-type metal ion transport system permease component
C3F22_RS07820	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C3F22_RS07830	COG4122	O-methyltransferase activity
C3F22_RS07865	COG2963	transposase activity
C3F22_RS07875	COG4372	Transposase
C3F22_RS07885	COG1137	ATPase activity
C3F22_RS07890	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C3F22_RS07900	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C3F22_RS07905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C3F22_RS07905	COG0517	IMP dehydrogenase activity
C3F22_RS07940	COG0625	glutathione transferase activity
C3F22_RS07945	COG0519	Catalyzes the synthesis of GMP from XMP
C3F22_RS07945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C3F22_RS07965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C3F22_RS07985	COG2391	methyltransferase activity
C3F22_RS08045	COG2267	carboxylic ester hydrolase activity
C3F22_RS08085	COG0352	thiamine-phosphate diphosphorylase activity
C3F22_RS08100	COG3025	triphosphatase activity
C3F22_RS08120	COG0612	Peptidase, M16
C3F22_RS08150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3F22_RS08200	COG2815	serine threonine protein kinase
C3F22_RS08200	COG0515	serine threonine protein kinase
C3F22_RS08220	COG3293	Transposase
C3F22_RS08240	COG1610	YqeY-like protein
C3F22_RS08255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3F22_RS08305	COG0778	Nitroreductase
C3F22_RS08315	COG0513	Belongs to the DEAD box helicase family
C3F22_RS08335	COG2363	Small membrane protein
C3F22_RS08360	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3F22_RS08370	COG0659	secondary active sulfate transmembrane transporter activity
C3F22_RS08375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C3F22_RS08395	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_RS08400	COG1309	transcriptional regulator
C3F22_RS08405	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS08410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C3F22_RS08415	COG1024	Enoyl-CoA hydratase
C3F22_RS08420	COG4770	biotin carboxylase activity
C3F22_RS08435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3F22_RS08440	COG2031	fatty acid transporter
C3F22_RS08455	COG0540	Belongs to the ATCase OTCase family
C3F22_RS08485	COG0667	Aldo Keto reductase
C3F22_RS08495	COG1765	OsmC-like protein
C3F22_RS08500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C3F22_RS08525	COG0714	Associated with various cellular activities
C3F22_RS08530	COG2879	small protein
C3F22_RS08535	COG1966	Carbon starvation protein
C3F22_RS08540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C3F22_RS08580	COG1067	ATP-dependent peptidase activity
C3F22_RS08585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C3F22_RS08590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3F22_RS08595	COG0583	DNA-binding transcription factor activity
C3F22_RS08620	COG1686	Belongs to the peptidase S11 family
C3F22_RS08625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C3F22_RS08635	COG0488	(ABC) transporter
C3F22_RS08640	COG3293	Transposase
C3F22_RS08650	COG0488	(ABC) transporter
C3F22_RS08655	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C3F22_RS08655	COG2755	lipolytic protein G-D-S-L family
C3F22_RS08665	COG0482	sulfurtransferase activity
C3F22_RS08685	COG3385	transposase activity
C3F22_RS08700	COG0616	signal peptide processing
C3F22_RS08710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C3F22_RS08725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3F22_RS08730	COG1113	amino acid transport
C3F22_RS08735	COG3961	Belongs to the TPP enzyme family
C3F22_RS08740	COG1522	sequence-specific DNA binding
C3F22_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_RS08755	COG0076	glutamate decarboxylase activity
C3F22_RS08760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3F22_RS08770	COG0671	phosphoesterase, PA-phosphatase related
C3F22_RS08795	COG1733	regulation of RNA biosynthetic process
C3F22_RS08815	COG3040	lipid binding
C3F22_RS08820	COG0556	nucleotide-excision repair
C3F22_RS08860	COG2175	clavaminate synthase activity
C3F22_RS08875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C3F22_RS08880	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS08890	COG2084	Dehydrogenase
C3F22_RS08895	COG2233	PERMEase
C3F22_RS08900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3F22_RS08905	COG0251	oxidation-reduction process
C3F22_RS08910	COG1335	isochorismatase
C3F22_RS08915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3F22_RS08920	COG0596	Alpha beta hydrolase
C3F22_RS08930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3F22_RS08935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3F22_RS08940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3F22_RS08980	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C3F22_RS08985	COG3161	chorismate lyase activity
C3F22_RS08995	COG0174	glutamine synthetase
C3F22_RS09005	COG0512	Glutamine amidotransferase of anthranilate synthase
C3F22_RS09010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C3F22_RS09030	COG0302	gtp cyclohydrolase
C3F22_RS09045	COG3706	GGDEF domain
C3F22_RS09060	COG3739	integral membrane protein
C3F22_RS09075	COG1741	Belongs to the pirin family
C3F22_RS09105	COG1546	Belongs to the CinA family
C3F22_RS09105	COG1058	Belongs to the CinA family
C3F22_RS09125	COG0281	malic enzyme
C3F22_RS09165	COG3706	GGDEF domain
C3F22_RS09180	COG1785	Belongs to the alkaline phosphatase family
C3F22_RS09185	COG1785	Belongs to the alkaline phosphatase family
C3F22_RS09205	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3F22_RS09205	COG1902	pentaerythritol trinitrate reductase activity
C3F22_RS09220	COG3706	GGDEF domain
C3F22_RS09225	COG0418	dihydroorotase activity
C3F22_RS09230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C3F22_RS09250	COG0833	amino acid
C3F22_RS09290	COG4239	(ABC) transporter, permease
C3F22_RS09295	COG4174	ABC transporter (Permease)
C3F22_RS09300	COG4166	transmembrane transport
C3F22_RS09305	COG0741	lytic transglycosylase activity
C3F22_RS09305	COG1388	LysM domain
C3F22_RS09320	COG2816	NAD+ diphosphatase activity
C3F22_RS09325	COG0657	acetylesterase activity
C3F22_RS09340	COG3107	peptidoglycan biosynthetic process
C3F22_RS09355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_RS09360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_RS09380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C3F22_RS09390	COG2155	Conserved Protein
C3F22_RS09395	COG0006	proline dipeptidase activity
C3F22_RS09420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C3F22_RS09430	COG2234	aminopeptidase activity
C3F22_RS09435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C3F22_RS09440	COG3384	dioxygenase
C3F22_RS09450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C3F22_RS09455	COG2878	Part of a membrane complex involved in electron transport
C3F22_RS09460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C3F22_RS09485	COG0768	penicillin binding
C3F22_RS09490	COG0742	ribosomal rna small subunit methyltransferase
C3F22_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS09540	COG0459	protein refolding
C3F22_RS09555	COG1597	lipid kinase activity
C3F22_RS09570	COG0477	Major facilitator Superfamily
C3F22_RS09585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C3F22_RS09610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3F22_RS09610	COG3321	synthase
C3F22_RS09610	COG0604	alcohol dehydrogenase
C3F22_RS09610	COG4221	oxidoreductase activity
C3F22_RS09620	COG3118	belongs to the thioredoxin family
C3F22_RS09665	COG2268	Band 7 protein
C3F22_RS09670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C3F22_RS09680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3F22_RS09695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3F22_RS09700	COG1053	succinate dehydrogenase
C3F22_RS09705	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C3F22_RS09725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C3F22_RS09725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3F22_RS09740	COG0589	response to stress
C3F22_RS09765	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS09800	COG3328	transposase activity
C3F22_RS09810	COG2321	neutral zinc metallopeptidase
C3F22_RS09815	COG2354	Protein conserved in bacteria
C3F22_RS09820	COG3293	Transposase
C3F22_RS09850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C3F22_RS09855	COG1773	rubredoxin
C3F22_RS09860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_RS09870	COG0583	DNA-binding transcription factor activity
C3F22_RS09890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3F22_RS09900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C3F22_RS09905	COG4181	ATPase activity
C3F22_RS09935	COG3293	Transposase
C3F22_RS09940	COG4771	TonB-dependent receptor
C3F22_RS09955	COG4607	ABC-type enterochelin transport system periplasmic component
C3F22_RS09965	COG0306	phosphate transporter
C3F22_RS09990	COG3328	transposase activity
C3F22_RS10010	COG2376	Dihydroxyacetone kinase
C3F22_RS10015	COG2066	Belongs to the glutaminase family
C3F22_RS10020	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS10030	COG0525	valine-tRNA ligase activity
C3F22_RS10040	COG2852	Protein conserved in bacteria
C3F22_RS10055	COG2323	membrane
C3F22_RS10060	COG0546	phosphoglycolate phosphatase activity
C3F22_RS10080	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3F22_RS10095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3F22_RS10100	COG0142	geranyltranstransferase activity
C3F22_RS10105	COG2828	Protein conserved in bacteria
C3F22_RS10110	COG1113	amino acid transport
C3F22_RS10130	COG0560	Phosphoserine phosphatase
C3F22_RS10140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3F22_RS10150	COG0424	maF-like protein
C3F22_RS10155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C3F22_RS10160	COG1792	Involved in formation and maintenance of cell shape
C3F22_RS10165	COG1077	Cell shape determining protein MreB Mrl
C3F22_RS10170	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C3F22_RS10180	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C3F22_RS10200	COG0697	spore germination
C3F22_RS10210	COG3590	peptidase
C3F22_RS10215	COG3590	peptidase
C3F22_RS10235	COG3293	Transposase
C3F22_RS10240	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C3F22_RS10250	COG3328	transposase activity
C3F22_RS10260	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C3F22_RS10265	COG2223	nitrite transmembrane transporter activity
C3F22_RS10275	COG0500	methyltransferase
C3F22_RS10300	COG0783	Belongs to the Dps family
C3F22_RS10325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C3F22_RS10330	COG4149	molybdate abc transporter
C3F22_RS10335	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3F22_RS10340	COG0303	'Molybdopterin
C3F22_RS10345	COG0315	cyclic pyranopterin monophosphate synthase activity
C3F22_RS10345	COG0521	Mo-molybdopterin cofactor biosynthetic process
C3F22_RS10350	COG0314	molybdopterin synthase activity
C3F22_RS10360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C3F22_RS10370	COG0243	molybdopterin cofactor binding
C3F22_RS10375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_RS10380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_RS10385	COG2223	nitrite transmembrane transporter activity
C3F22_RS10395	COG0582	viral genome integration into host DNA
C3F22_RS10440	COG4372	Transposase
C3F22_RS10485	COG3617	BRO family, N-terminal domain
C3F22_RS10525	COG0582	viral genome integration into host DNA
C3F22_RS10535	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_RS10555	COG2186	Transcriptional regulator
C3F22_RS10560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3F22_RS10565	COG2814	Major facilitator Superfamily
C3F22_RS10570	COG2084	Dehydrogenase
C3F22_RS10580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3F22_RS10590	COG0583	DNA-binding transcription factor activity
C3F22_RS10600	COG0129	dihydroxy-acid dehydratase activity
C3F22_RS10605	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_RS10630	COG3177	Filamentation induced by cAMP protein fic
C3F22_RS10665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3F22_RS10685	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS10695	COG3293	Transposase
C3F22_RS10755	COG0131	Imidazoleglycerol-phosphate dehydratase
C3F22_RS10755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C3F22_RS10770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C3F22_RS10775	COG2814	Major facilitator Superfamily
C3F22_RS10780	COG1566	PFAM secretion protein HlyD family protein
C3F22_RS10785	COG2050	protein possibly involved in aromatic compounds catabolism
C3F22_RS10795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3F22_RS10800	COG1090	epimerase
C3F22_RS10810	COG0420	3'-5' exonuclease activity
C3F22_RS10840	COG0735	belongs to the Fur family
C3F22_RS10845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3F22_RS10850	COG2914	Belongs to the UPF0125 (RnfH) family
C3F22_RS10865	COG0121	glutamine amidotransferase
C3F22_RS10900	COG0756	dUTP diphosphatase activity
C3F22_RS10910	COG2885	chlorophyll binding
C3F22_RS10915	COG0204	Acyl-transferase
C3F22_RS10930	COG2894	cell division
C3F22_RS10945	COG1674	ftsk spoiiie
C3F22_RS10945	COG0531	amino acid
C3F22_RS10955	COG0492	ferredoxin-NADP+ reductase activity
C3F22_RS10960	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C3F22_RS10970	COG0456	acetyltransferase
C3F22_RS10995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C3F22_RS11010	COG1981	membrane
C3F22_RS11015	COG1113	amino acid transport
C3F22_RS11020	COG0251	oxidation-reduction process
C3F22_RS11040	COG1652	LysM domain
C3F22_RS11045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3F22_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS11060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C3F22_RS11065	COG1399	metal-binding, possibly nucleic acid-binding protein
C3F22_RS11070	COG3101	peptidyl-lysine hydroxylation
C3F22_RS11075	COG0009	L-threonylcarbamoyladenylate synthase
C3F22_RS11090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C3F22_RS11095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C3F22_RS11125	COG0339	signal peptide processing
C3F22_RS11135	COG4166	transmembrane transport
C3F22_RS11145	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C3F22_RS11165	COG2193	ferroxidase activity
C3F22_RS11170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3F22_RS11175	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C3F22_RS11180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C3F22_RS11190	COG1196	nuclear chromosome segregation
C3F22_RS11205	COG0730	response to heat
C3F22_RS11220	COG3545	Serine hydrolase
C3F22_RS11230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C3F22_RS11240	COG2226	methyltransferase
C3F22_RS11250	COG3327	negative regulation of DNA-templated transcription, initiation
C3F22_RS11255	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C3F22_RS11260	COG0183	Belongs to the thiolase family
C3F22_RS11265	COG1024	Enoyl-CoA hydratase
C3F22_RS11270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C3F22_RS11275	COG2151	metal-sulfur cluster biosynthetic enzyme
C3F22_RS11280	COG3396	Phenylacetate-CoA oxygenase
C3F22_RS11285	COG3460	Phenylacetate-CoA oxygenase
C3F22_RS11290	COG3396	Phenylacetate-CoA oxygenase
C3F22_RS11295	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_RS11295	COG2030	dehydratase
C3F22_RS11300	COG2814	Major facilitator Superfamily
C3F22_RS11320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3F22_RS11330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C3F22_RS11350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C3F22_RS11365	COG1968	undecaprenyl-diphosphatase activity
C3F22_RS11370	COG1214	PFAM Peptidase M22, glycoprotease
C3F22_RS11380	COG0494	nUDIX hydrolase
C3F22_RS11470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C3F22_RS11475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C3F22_RS11560	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C3F22_RS11565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C3F22_RS11580	COG0450	alkyl hydroperoxide reductase
C3F22_RS11595	COG0285	dihydrofolate synthase activity
C3F22_RS11640	COG4206	TonB-dependent receptor
C3F22_RS11645	COG2096	Adenosyltransferase
C3F22_RS11660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C3F22_RS11665	COG2315	Protein conserved in bacteria
C3F22_RS11675	COG1113	amino acid transport
C3F22_RS11685	COG0745	RESPONSE REGULATOR receiver
C3F22_RS11690	COG2205	protein histidine kinase activity
C3F22_RS11700	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS11705	COG1960	acyl-CoA dehydrogenase activity
C3F22_RS11750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C3F22_RS11805	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C3F22_RS11810	COG2205	protein histidine kinase activity
C3F22_RS11825	COG1660	Displays ATPase and GTPase activities
C3F22_RS11840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3F22_RS11845	COG0617	tRNA 3'-terminal CCA addition
C3F22_RS11850	COG1596	polysaccharide export
C3F22_RS11850	COG1555	photosystem II stabilization
C3F22_RS11855	COG3956	TIGRFAM MazG family protein
C3F22_RS11860	COG4221	oxidoreductase activity
C3F22_RS11870	COG0675	Transposase, IS605 OrfB family
C3F22_RS11915	COG1426	Protein conserved in bacteria
C3F22_RS11935	COG2975	iron-sulfur cluster assembly
C3F22_RS11960	COG0028	Belongs to the TPP enzyme family
C3F22_RS11970	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS12005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_RS12010	COG0577	efflux transmembrane transporter activity
C3F22_RS12010	COG1136	(ABC) transporter
C3F22_RS12015	COG1538	Outer membrane efflux protein
C3F22_RS12025	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C3F22_RS12035	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C3F22_RS12040	COG1162	GTPase activity
C3F22_RS12050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C3F22_RS12070	COG0084	hydrolase, TatD family'
C3F22_RS12085	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C3F22_RS12115	COG4251	negative regulation of phosphorylation
C3F22_RS12115	COG3706	GGDEF domain
C3F22_RS12115	COG2203	Gaf domain
C3F22_RS12115	COG5001	Diguanylate cyclase
C3F22_RS12165	COG0793	Belongs to the peptidase S41A family
C3F22_RS12190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C3F22_RS12195	COG0857	belongs to the CobB CobQ family
C3F22_RS12195	COG0280	phosphate acetyltransferase
C3F22_RS12205	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C3F22_RS12205	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C3F22_RS12220	COG0740	serine-type endopeptidase activity
C3F22_RS12230	COG4774	siderophore transport
C3F22_RS12240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C3F22_RS12245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3F22_RS12250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3F22_RS12250	COG2813	Specifically methylates the guanine in position
C3F22_RS12310	COG3040	lipid binding
C3F22_RS12320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3F22_RS12355	COG0788	formyltetrahydrofolate deformylase activity
C3F22_RS12380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3F22_RS12380	COG4651	solute:proton antiporter activity
C3F22_RS12395	COG0724	RNA recognition motif
C3F22_RS12400	COG0210	DNA helicase
C3F22_RS12405	COG1929	Belongs to the glycerate kinase type-1 family
C3F22_RS12455	COG2900	Belongs to the SlyX family
C3F22_RS12460	COG0488	(ABC) transporter
C3F22_RS12465	COG1560	Kdo2-lipid A biosynthetic process
C3F22_RS12525	COG0473	3-isopropylmalate dehydrogenase activity
C3F22_RS12540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C3F22_RS12595	COG0753	catalase activity
C3F22_RS12635	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3F22_RS12640	COG3384	dioxygenase
C3F22_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS12660	COG4638	Rieske (2fe-2S)
C3F22_RS12665	COG0583	DNA-binding transcription factor activity
C3F22_RS12685	COG4569	acetaldehyde dehydrogenase (acetylating) activity
C3F22_RS12690	COG3971	2-oxopent-4-enoate hydratase activity
C3F22_RS12695	COG0546	phosphoglycolate phosphatase activity
C3F22_RS12710	COG1530	ribonuclease E activity
C3F22_RS12715	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_RS12740	COG1983	PspC domain protein
C3F22_RS12750	COG0471	metal ion transport
C3F22_RS12755	COG0617	tRNA 3'-terminal CCA addition
C3F22_RS12755	COG0517	IMP dehydrogenase activity
C3F22_RS12755	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C3F22_RS12765	COG0752	glycyl-tRNA synthetase alpha subunit
C3F22_RS12770	COG0751	glycine-tRNA ligase activity
C3F22_RS12795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3F22_RS12810	COG2226	methyltransferase
C3F22_RS12820	COG0644	oxidoreductase
C3F22_RS12830	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C3F22_RS12840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3F22_RS12855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C3F22_RS12865	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C3F22_RS12865	COG0644	oxidoreductase
C3F22_RS12900	COG0425	Belongs to the sulfur carrier protein TusA family
C3F22_RS12905	COG4535	Mg2 and Co2 transporter CorC
C3F22_RS12930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3F22_RS12940	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C3F22_RS12965	COG0789	Transcriptional regulator
C3F22_RS12970	COG2841	Protein conserved in bacteria
C3F22_RS12980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C3F22_RS12985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3F22_RS12990	COG1074	ATP-dependent DNA helicase activity
C3F22_RS12995	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C3F22_RS13015	COG2226	methyltransferase
C3F22_RS13025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C3F22_RS13070	COG0427	acetyl-CoA hydrolase
C3F22_RS13075	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3F22_RS13105	COG0326	Molecular chaperone. Has ATPase activity
C3F22_RS13115	COG3047	cAMP biosynthetic process
C3F22_RS13120	COG2056	Na+-H+ antiporter family
C3F22_RS13140	COG4372	Transposase
C3F22_RS13160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C3F22_RS13165	COG0085	RNA polymerase activity
C3F22_RS13175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C3F22_RS13235	COG0546	phosphoglycolate phosphatase activity
C3F22_RS13265	COG0824	Thioesterase
C3F22_RS13285	COG0181	hydroxymethylbilane synthase activity
C3F22_RS13295	COG3275	phosphorelay sensor kinase activity
C3F22_RS13325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C3F22_RS13355	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3F22_RS13355	COG1024	Enoyl-CoA hydratase
C3F22_RS13430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C3F22_RS13475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3F22_RS13525	COG3158	transport of potassium into the cell
C3F22_RS13590	COG0629	single-stranded DNA binding
C3F22_RS13595	COG2814	Major facilitator Superfamily
C3F22_RS13615	COG0352	thiamine-phosphate diphosphorylase activity
C3F22_RS13615	COG0351	phosphomethylpyrimidine kinase
C3F22_RS13615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3F22_RS13650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3F22_RS13660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3F22_RS13665	COG3162	membrane
C3F22_RS13670	COG2205	protein histidine kinase activity
C3F22_RS13670	COG2198	Histidine kinase
C3F22_RS13670	COG0784	Response regulator, receiver
C3F22_RS13685	COG0431	NADPH-dependent FMN reductase
C3F22_RS13695	COG0307	riboflavin synthase, alpha
C3F22_RS13710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3F22_RS13720	COG0668	transmembrane transport
C3F22_RS13725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3F22_RS13730	COG1519	Transferase
C3F22_RS13735	COG1902	pentaerythritol trinitrate reductase activity
C3F22_RS13760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3F22_RS13785	COG0426	domain, Protein
C3F22_RS13785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3F22_RS13790	COG2119	membrane
C3F22_RS13820	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C3F22_RS13830	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C3F22_RS13840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C3F22_RS13855	COG0189	ligase activity
C3F22_RS13875	COG0708	Exodeoxyribonuclease III
C3F22_RS13895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C3F22_RS13950	COG3150	esterase
C3F22_RS13960	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C3F22_RS13965	COG2918	glutathione biosynthetic process
C3F22_RS13980	COG2733	membrane
C3F22_RS14020	COG0753	catalase activity
C3F22_RS14040	COG3830	Belongs to the UPF0237 family
C3F22_RS14040	COG0560	Phosphoserine phosphatase
C3F22_RS14055	COG0385	Bile acid
C3F22_RS14060	COG1335	isochorismatase
C3F22_RS14070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C3F22_RS14080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C3F22_RS14085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C3F22_RS14090	COG3300	MHYT domain
C3F22_RS14090	COG5001	Diguanylate cyclase
C3F22_RS14095	COG2983	Belongs to the UPF0260 family
C3F22_RS14100	COG5487	UPF0391 membrane protein
C3F22_RS14110	COG3023	N-Acetylmuramoyl-L-alanine amidase
C3F22_RS14120	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C3F22_RS14125	COG1309	transcriptional regulator
C3F22_RS14130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3F22_RS14135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C3F22_RS14140	COG0546	phosphoglycolate phosphatase activity
C3F22_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS14170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C3F22_RS14170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C3F22_RS14175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3F22_RS14180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3F22_RS14185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3F22_RS14190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3F22_RS14195	COG1116	anion transmembrane transporter activity
C3F22_RS14200	COG1309	transcriptional regulator
C3F22_RS14210	COG0196	riboflavin kinase activity
C3F22_RS14215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C3F22_RS14225	COG1047	Peptidyl-prolyl cis-trans
C3F22_RS14245	COG2133	pyrroloquinoline quinone binding
C3F22_RS14250	COG3706	GGDEF domain
C3F22_RS14250	COG5001	Diguanylate cyclase
C3F22_RS14250	COG2203	Gaf domain
C3F22_RS14250	COG4251	negative regulation of phosphorylation
C3F22_RS14300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C3F22_RS14310	COG0657	acetylesterase activity
C3F22_RS14370	COG0488	(ABC) transporter
C3F22_RS14375	COG1063	alcohol dehydrogenase
C3F22_RS14385	COG0187	DNA topoisomerase II activity
C3F22_RS14395	COG0592	DNA-directed DNA polymerase activity
C3F22_RS14400	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C3F22_RS14410	COG0594	ribonuclease P activity
C3F22_RS14415	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C3F22_RS14420	COG0706	membrane insertase activity
C3F22_RS14480	COG0402	S-adenosylhomocysteine deaminase activity
C3F22_RS14485	COG0861	Integral membrane protein TerC family
C3F22_RS14490	COG2814	Major facilitator Superfamily
C3F22_RS14520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C3F22_RS14535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C3F22_RS14540	COG2951	lytic endotransglycosylase activity
C3F22_RS14545	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C3F22_RS14550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C3F22_RS14585	COG2814	Major facilitator Superfamily
C3F22_RS14590	COG2814	Major facilitator Superfamily
C3F22_RS14605	COG0693	protein deglycase activity
C3F22_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_RS14625	COG0733	neurotransmitter:sodium symporter activity
C3F22_RS14635	COG0428	transporter
C3F22_RS14650	COG0129	dihydroxy-acid dehydratase activity
C3F22_RS14655	COG0129	dihydroxy-acid dehydratase activity
C3F22_RS14680	COG2233	PERMEase
C3F22_RS14690	COG1309	transcriptional regulator
C3F22_RS14700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_RS14750	COG0675	Transposase, IS605 OrfB family
C3F22_RS14760	COG1064	alcohol dehydrogenase
C3F22_RS14765	COG2818	Glycosylase
C3F22_RS14775	COG0739	heme binding
C3F22_RS14780	COG1194	a g-specific adenine glycosylase
C3F22_RS14810	COG1596	polysaccharide export
C3F22_RS14820	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C3F22_RS14850	COG0463	Glycosyl transferase, family 2
C3F22_RS14865	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS14890	COG4372	Transposase
C3F22_RS14900	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS14915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3F22_RS14945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C3F22_RS14990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3F22_RS15000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3F22_RS15010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3F22_RS15020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C3F22_RS15035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3F22_RS15040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C3F22_RS15085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C3F22_RS15095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C3F22_RS15100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C3F22_RS15110	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C3F22_RS15150	COG4716	Myosin-crossreactive antigen
C3F22_RS15165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C3F22_RS15165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3F22_RS15170	COG1105	Belongs to the carbohydrate kinase PfkB family
C3F22_RS15175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3F22_RS15175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3F22_RS15175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C3F22_RS15185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3F22_RS15190	COG3550	peptidyl-serine autophosphorylation
C3F22_RS15245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3F22_RS15260	COG0531	amino acid
C3F22_RS15295	COG1203	CRISPR-associated helicase, Cas3
C3F22_RS15320	COG3756	Protein conserved in bacteria
C3F22_RS15365	COG1192	Involved in chromosome partitioning
C3F22_RS15380	COG0586	Pfam SNARE associated Golgi protein
C3F22_RS15385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C3F22_RS15385	COG0519	Catalyzes the synthesis of GMP from XMP
C3F22_RS15395	COG3706	GGDEF domain
C3F22_RS15440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3F22_RS15445	COG0534	Mate efflux family protein
C3F22_RS15450	COG0436	Aminotransferase
C3F22_RS15510	COG3328	transposase activity
C3F22_RS15520	COG2837	iron assimilation
C3F22_RS15525	COG1280	lysine exporter protein (LysE YggA)
C3F22_RS15535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3F22_RS15540	COG1121	(ABC) transporter
C3F22_RS15590	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C3F22_RS15600	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_RS15615	COG0386	Belongs to the glutathione peroxidase family
C3F22_RS15620	COG0386	Belongs to the glutathione peroxidase family
C3F22_RS15625	COG0697	spore germination
C3F22_RS15640	COG0758	DNA mediated transformation
C3F22_RS15695	COG2814	Major facilitator Superfamily
C3F22_RS15715	COG0477	Major facilitator Superfamily
C3F22_RS15720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C3F22_RS15745	COG1253	flavin adenine dinucleotide binding
C3F22_RS15755	COG2860	membrane
C3F22_RS15760	COG0477	Major facilitator Superfamily
C3F22_RS15770	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_RS15785	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C3F22_RS15805	COG0606	chelatase, subunit chli
C3F22_RS15815	COG0347	Belongs to the P(II) protein family
C3F22_RS15820	COG0004	ammonium transporteR
C3F22_RS15830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3F22_RS15830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3F22_RS15845	COG0586	Pfam SNARE associated Golgi protein
C3F22_RS15865	COG0795	lipopolysaccharide-transporting ATPase activity
C3F22_RS15870	COG0795	lipopolysaccharide-transporting ATPase activity
C3F22_RS15875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C3F22_RS15880	COG0793	Belongs to the peptidase S41A family
C3F22_RS15890	COG2205	protein histidine kinase activity
C3F22_RS15895	COG2197	response regulator
C3F22_RS15900	COG1686	Belongs to the peptidase S11 family
C3F22_RS15905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C3F22_RS15915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3F22_RS15920	COG4974	Belongs to the 'phage' integrase family
C3F22_RS15945	COG0772	Belongs to the SEDS family
C3F22_RS15955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C3F22_RS15960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3F22_RS15965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C3F22_RS15970	COG0494	nUDIX hydrolase
C3F22_RS15985	COG1538	Outer membrane efflux protein
C3F22_RS16025	COG0675	Transposase, IS605 OrfB family
C3F22_RS16035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C3F22_RS16060	COG0497	DNA recombination
C3F22_RS16075	COG3328	transposase activity
C3F22_RS16105	COG1252	NADH dehydrogenase
C3F22_RS16110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C3F22_RS16135	COG4372	Transposase
C3F22_RS16185	COG1063	alcohol dehydrogenase
C3F22_RS16250	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS16260	COG1373	ATPase (AAA superfamily
C3F22_RS16280	COG1475	DNA binding
C3F22_RS16285	COG1192	Involved in chromosome partitioning
C3F22_RS16330	COG3188	usher protein
C3F22_RS16430	COG2963	transposase activity
C3F22_RS16440	COG4372	Transposase
C3F22_RS16480	COG1846	Transcriptional regulator
C3F22_RS16485	COG1764	response to oxidative stress
C3F22_RS16495	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C3F22_RS16500	COG3706	GGDEF domain
C3F22_RS16530	COG1192	Involved in chromosome partitioning
C3F22_RS16590	COG0739	heme binding
C3F22_RS16590	COG0741	lytic transglycosylase activity
C3F22_RS16590	COG1196	nuclear chromosome segregation
C3F22_RS16605	COG0741	lytic transglycosylase activity
C3F22_RS16605	COG1196	nuclear chromosome segregation
C3F22_RS16605	COG0739	heme binding
C3F22_RS16630	COG1525	nuclease
C3F22_RS16660	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS16690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3F22_RS16755	COG4106	trans-aconitate 2-methyltransferase activity
C3F22_RS16800	COG1215	transferase activity, transferring glycosyl groups
C3F22_RS16815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3F22_RS16860	COG4774	siderophore transport
C3F22_RS16875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_RS16915	COG1454	alcohol dehydrogenase
C3F22_RS16935	COG4372	Transposase
C3F22_RS16945	COG2963	transposase activity
C3F22_RS16955	COG4774	siderophore transport
C3F22_RS16960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3F22_RS17015	COG1192	Involved in chromosome partitioning
C3F22_RS17050	COG1346	cytolysis
C3F22_RS17055	COG1380	Effector of murein hydrolase LrgA
C3F22_RS17060	COG0583	DNA-binding transcription factor activity
C3F22_RS17065	COG1309	transcriptional regulator
C3F22_RS17070	COG0604	alcohol dehydrogenase
C3F22_RS17100	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_RS17140	COG4372	Transposase
C3F22_RS17160	COG3706	GGDEF domain
C3F22_RS17170	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C3F22_RS17230	COG2072	flavoprotein involved in K transport
C3F22_RS17235	COG0431	NADPH-dependent FMN reductase
C3F22_RS17240	COG0798	PFAM Bile acid sodium symporter
C3F22_RS17250	COG0640	Transcriptional regulator
C3F22_RS17335	COG3174	membrane
C3F22_RS17340	COG2205	protein histidine kinase activity
C3F22_RS17355	COG2132	Multicopper oxidase
C3F22_RS17375	COG0431	NADPH-dependent FMN reductase
C3F22_RS17405	COG2963	transposase activity
C3F22_RS17415	COG4372	Transposase
C3F22_RS17480	COG4372	Transposase
C3F22_RS17495	COG4372	Transposase
C3F22_RS17515	COG1373	ATPase (AAA superfamily
C3F22_RS17545	COG2009	succinate dehydrogenase
C3F22_RS17565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C3F22_RS17575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C3F22_RS17615	COG0625	glutathione transferase activity
C3F22_RS17620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_RS17645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3F22_RS17690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_RS17695	COG0183	Belongs to the thiolase family
C3F22_RS17710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_RS17715	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C3F22_RS17720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_RS17755	COG0475	glutathione-regulated potassium exporter activity
C3F22_RS17755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3F22_RS17770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C3F22_RS17780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3F22_RS17785	COG0022	dehydrogenase e1 component
C3F22_RS17790	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3F22_RS17815	COG1063	alcohol dehydrogenase
C3F22_RS17820	COG1802	Transcriptional regulator
C3F22_RS17845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3F22_RS17850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3F22_RS17855	COG1120	ATPase activity
C3F22_RS17885	COG0642	Histidine kinase
C3F22_RS17890	COG0745	RESPONSE REGULATOR receiver
C3F22_RS17895	COG2194	sulfuric ester hydrolase activity
C3F22_RS17905	COG0583	DNA-binding transcription factor activity
C3F22_RS17910	COG0730	response to heat
C3F22_RS17915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3F22_RS17920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C3F22_RS17955	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C3F22_RS18015	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_RS18040	COG0579	oxidoreductase
C3F22_RS18070	COG2130	NADP-dependent
C3F22_RS18075	COG1309	transcriptional regulator
C3F22_RS18085	COG1902	pentaerythritol trinitrate reductase activity
C3F22_RS18095	COG1979	alcohol dehydrogenase
C3F22_RS18120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C3F22_RS18135	COG0604	alcohol dehydrogenase
C3F22_RS18135	COG3321	synthase
C3F22_RS18140	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C3F22_RS18145	COG0583	DNA-binding transcription factor activity
C3F22_RS18150	COG4221	oxidoreductase activity
C3F22_RS18215	COG0659	secondary active sulfate transmembrane transporter activity