locus-tag	class	description
K6I41_RS00010	COG0592	DNA-directed DNA polymerase activity
K6I41_RS00020	COG0187	DNA topoisomerase II activity
K6I41_RS00035	COG0488	(ABC) transporter
K6I41_RS00060	COG0596	Alpha beta hydrolase
K6I41_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K6I41_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K6I41_RS00105	COG0733	neurotransmitter:sodium symporter activity
K6I41_RS00145	COG2233	PERMEase
K6I41_RS00160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6I41_RS00195	COG2814	Major facilitator Superfamily
K6I41_RS00200	COG0656	L-ascorbic acid biosynthetic process
K6I41_RS00205	COG0583	DNA-binding transcription factor activity
K6I41_RS00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6I41_RS00225	COG1064	alcohol dehydrogenase
K6I41_RS00230	COG2818	Glycosylase
K6I41_RS00245	COG1194	a g-specific adenine glycosylase
K6I41_RS00260	COG5487	UPF0391 membrane protein
K6I41_RS00265	COG2983	Belongs to the UPF0260 family
K6I41_RS00270	COG2133	pyrroloquinoline quinone binding
K6I41_RS00275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K6I41_RS00280	COG2116	formate transmembrane transporter activity
K6I41_RS00300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6I41_RS00305	COG1335	isochorismatase
K6I41_RS00310	COG0385	Bile acid
K6I41_RS00315	COG0534	Mate efflux family protein
K6I41_RS00320	COG1683	Conserved Protein
K6I41_RS00335	COG0346	lactoylglutathione lyase activity
K6I41_RS00340	COG0625	glutathione transferase activity
K6I41_RS00350	COG1113	amino acid transport
K6I41_RS00360	COG0523	cobalamin synthesis protein
K6I41_RS00370	COG2188	Transcriptional regulator
K6I41_RS00400	COG0010	Belongs to the arginase family
K6I41_RS00410	COG0546	phosphoglycolate phosphatase activity
K6I41_RS00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K6I41_RS00420	COG1280	lysine exporter protein (LysE YggA)
K6I41_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K6I41_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K6I41_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K6I41_RS00545	COG0534	Mate efflux family protein
K6I41_RS00550	COG0436	Aminotransferase
K6I41_RS00555	COG2733	membrane
K6I41_RS00570	COG2918	glutathione biosynthetic process
K6I41_RS00605	COG3150	esterase
K6I41_RS00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
K6I41_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6I41_RS00635	COG2233	PERMEase
K6I41_RS00640	COG2351	hydroxyisourate hydrolase activity
K6I41_RS00675	COG3706	GGDEF domain
K6I41_RS00690	COG1393	Belongs to the ArsC family
K6I41_RS00695	COG0708	Exodeoxyribonuclease III
K6I41_RS00715	COG0189	ligase activity
K6I41_RS00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K6I41_RS00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K6I41_RS00760	COG4942	peptidase
K6I41_RS00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
K6I41_RS00780	COG2119	membrane
K6I41_RS00785	COG4774	siderophore transport
K6I41_RS00790	COG0426	domain, Protein
K6I41_RS00790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K6I41_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K6I41_RS00830	COG1902	pentaerythritol trinitrate reductase activity
K6I41_RS00835	COG1519	Transferase
K6I41_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K6I41_RS00845	COG0668	transmembrane transport
K6I41_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K6I41_RS00860	COG1335	isochorismatase
K6I41_RS00865	COG1522	sequence-specific DNA binding
K6I41_RS00890	COG0784	Response regulator, receiver
K6I41_RS00890	COG2205	protein histidine kinase activity
K6I41_RS00890	COG2198	Histidine kinase
K6I41_RS00895	COG3162	membrane
K6I41_RS00900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6I41_RS00910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6I41_RS00930	COG1309	transcriptional regulator
K6I41_RS00950	COG4221	oxidoreductase activity
K6I41_RS00955	COG0789	Transcriptional regulator
K6I41_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
K6I41_RS00960	COG0351	phosphomethylpyrimidine kinase
K6I41_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K6I41_RS00970	COG2814	Major facilitator Superfamily
K6I41_RS00975	COG0629	single-stranded DNA binding
K6I41_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K6I41_RS00995	COG1113	amino acid transport
K6I41_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K6I41_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS01020	COG1335	isochorismatase
K6I41_RS01060	COG2814	Major facilitator Superfamily
K6I41_RS01065	COG0583	DNA-binding transcription factor activity
K6I41_RS01090	COG1309	transcriptional regulator
K6I41_RS01130	COG0667	Aldo Keto reductase
K6I41_RS01170	COG1733	regulation of RNA biosynthetic process
K6I41_RS01175	COG2249	NAD(P)H dehydrogenase (quinone) activity
K6I41_RS01185	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
K6I41_RS01190	COG2207	Transcriptional regulator
K6I41_RS01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K6I41_RS01260	COG2329	Antibiotic biosynthesis monooxygenase
K6I41_RS01265	COG0697	spore germination
K6I41_RS01275	COG4619	ABC transporter
K6I41_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K6I41_RS01325	COG0427	acetyl-CoA hydrolase
K6I41_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
K6I41_RS01355	COG4221	oxidoreductase activity
K6I41_RS01365	COG2814	Major facilitator Superfamily
K6I41_RS01375	COG2873	o-acetylhomoserine
K6I41_RS01380	COG0488	(ABC) transporter
K6I41_RS01445	COG0833	amino acid
K6I41_RS01500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K6I41_RS01505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K6I41_RS01520	COG2226	methyltransferase
K6I41_RS01570	COG0067	glutamate synthase
K6I41_RS01570	COG0070	glutamate synthase
K6I41_RS01570	COG0069	glutamate synthase activity
K6I41_RS01575	COG0493	'glutamate synthase
K6I41_RS01585	COG1704	LemA family
K6I41_RS01590	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
K6I41_RS01605	COG3307	-O-antigen
K6I41_RS01625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K6I41_RS01640	COG0194	GDP metabolic process
K6I41_RS01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K6I41_RS01700	COG0335	large ribosomal subunit rRNA binding
K6I41_RS01710	COG5380	lipid catabolic process
K6I41_RS01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K6I41_RS01730	COG5006	permease, DMT superfamily
K6I41_RS01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K6I41_RS01745	COG0277	FAD linked oxidase domain protein
K6I41_RS01765	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
K6I41_RS01770	COG2249	NAD(P)H dehydrogenase (quinone) activity
K6I41_RS01790	COG1289	transmembrane transporter activity
K6I41_RS01800	COG0628	permease
K6I41_RS01805	COG1192	Involved in chromosome partitioning
K6I41_RS01835	COG0833	amino acid
K6I41_RS01840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K6I41_RS01845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K6I41_RS01855	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS01895	COG0583	DNA-binding transcription factor activity
K6I41_RS01925	COG0752	glycyl-tRNA synthetase alpha subunit
K6I41_RS01955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K6I41_RS01955	COG0517	IMP dehydrogenase activity
K6I41_RS01955	COG0617	tRNA 3'-terminal CCA addition
K6I41_RS01960	COG1983	PspC domain protein
K6I41_RS01970	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS01985	COG0408	coproporphyrinogen oxidase activity
K6I41_RS02005	COG0513	Belongs to the DEAD box helicase family
K6I41_RS02015	COG1127	ABC transporter
K6I41_RS02020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K6I41_RS02030	COG2854	intermembrane phospholipid transfer
K6I41_RS02040	COG0598	Magnesium transport protein CorA
K6I41_RS02050	COG0494	nUDIX hydrolase
K6I41_RS02055	COG1040	competence protein
K6I41_RS02060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K6I41_RS02080	COG1946	Acyl-CoA thioesterase
K6I41_RS02085	COG1301	dicarboxylic acid transport
K6I41_RS02100	COG1959	2 iron, 2 sulfur cluster binding
K6I41_RS02105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6I41_RS02105	COG1017	nitric oxide dioxygenase activity
K6I41_RS02115	COG0433	COG0433 Predicted ATPase
K6I41_RS02120	COG0626	cystathionine gamma-synthase activity
K6I41_RS02135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K6I41_RS02140	COG0088	Forms part of the polypeptide exit tunnel
K6I41_RS02160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K6I41_RS02275	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS02280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
K6I41_RS02310	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
K6I41_RS02315	COG0339	signal peptide processing
K6I41_RS02320	COG0557	exoribonuclease II activity
K6I41_RS02370	COG0179	Fumarylacetoacetate (FAA) hydrolase
K6I41_RS02375	COG1295	ribonuclease BN
K6I41_RS02410	COG1702	phosphate starvation-inducible protein PhoH
K6I41_RS02420	COG1196	nuclear chromosome segregation
K6I41_RS02420	COG0741	lytic transglycosylase activity
K6I41_RS02420	COG0739	heme binding
K6I41_RS02450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K6I41_RS02455	COG1183	phosphatidylcholine synthase activity
K6I41_RS02500	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS02505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K6I41_RS02510	COG1309	transcriptional regulator
K6I41_RS02525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K6I41_RS02530	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS02570	COG2969	positive regulation of protein catabolic process
K6I41_RS02580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K6I41_RS02585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K6I41_RS02590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K6I41_RS02595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K6I41_RS02600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K6I41_RS02620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K6I41_RS02630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K6I41_RS02635	COG1408	metallophosphoesterase
K6I41_RS02640	COG2885	chlorophyll binding
K6I41_RS02645	COG2199	diguanylate cyclase activity
K6I41_RS02680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6I41_RS02705	COG1607	acyl-coa hydrolase
K6I41_RS02740	COG2350	Protein conserved in bacteria
K6I41_RS02750	COG0613	PHP domain protein
K6I41_RS02755	COG3781	membrane
K6I41_RS02765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K6I41_RS02780	COG1862	Preprotein translocase
K6I41_RS02815	COG2205	protein histidine kinase activity
K6I41_RS02815	COG3437	response regulator, receiver
K6I41_RS02815	COG3850	Histidine kinase
K6I41_RS02815	COG4999	Histidine kinase
K6I41_RS02820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K6I41_RS02840	COG0726	polysaccharide deacetylase
K6I41_RS02845	COG0463	Glycosyl transferase, family 2
K6I41_RS02850	COG0438	transferase activity, transferring glycosyl groups
K6I41_RS02880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K6I41_RS02915	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS02920	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS02930	COG2205	protein histidine kinase activity
K6I41_RS02935	COG0745	RESPONSE REGULATOR receiver
K6I41_RS02945	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K6I41_RS02965	COG2096	Adenosyltransferase
K6I41_RS02970	COG4206	TonB-dependent receptor
K6I41_RS03015	COG0285	dihydrofolate synthase activity
K6I41_RS03035	COG0450	alkyl hydroperoxide reductase
K6I41_RS03050	COG0477	Major facilitator Superfamily
K6I41_RS03055	COG1272	protein, Hemolysin III
K6I41_RS03065	COG2153	protein acetylation
K6I41_RS03085	COG0183	Belongs to the thiolase family
K6I41_RS03090	COG2207	Transcriptional regulator
K6I41_RS03110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6I41_RS03125	COG0183	Belongs to the thiolase family
K6I41_RS03135	COG2885	chlorophyll binding
K6I41_RS03135	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K6I41_RS03145	COG1690	Belongs to the RtcB family
K6I41_RS03150	COG0833	amino acid
K6I41_RS03160	COG2233	PERMEase
K6I41_RS03165	COG1217	gtp-binding protein TYPA
K6I41_RS03180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6I41_RS03190	COG2094	Belongs to the DNA glycosylase MPG family
K6I41_RS03195	COG4772	TonB-dependent receptor
K6I41_RS03200	COG1902	pentaerythritol trinitrate reductase activity
K6I41_RS03215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K6I41_RS03220	COG0354	folic acid binding
K6I41_RS03230	COG3189	MarR family transcriptional regulator
K6I41_RS03235	COG2824	Alkylphosphonate utilization operon protein PhnA
K6I41_RS03240	COG3422	double-strand break repair
K6I41_RS03280	COG0840	transmembrane signaling receptor activity
K6I41_RS03310	COG2832	Protein of unknown function (DUF454)
K6I41_RS03315	COG1376	ErfK ybiS ycfS ynhG family protein
K6I41_RS03355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K6I41_RS03365	COG1289	transmembrane transporter activity
K6I41_RS03370	COG2814	Major facilitator Superfamily
K6I41_RS03390	COG1115	amino acid carrier protein
K6I41_RS03395	COG1752	Esterase of the alpha-beta hydrolase superfamily
K6I41_RS03400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K6I41_RS03405	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
K6I41_RS03445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K6I41_RS03455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K6I41_RS03460	COG1077	Cell shape determining protein MreB Mrl
K6I41_RS03465	COG1792	Involved in formation and maintenance of cell shape
K6I41_RS03470	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K6I41_RS03475	COG0424	maF-like protein
K6I41_RS03480	COG1530	ribonuclease E activity
K6I41_RS03490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K6I41_RS03535	COG2207	Transcriptional regulator
K6I41_RS03590	COG1113	amino acid transport
K6I41_RS03595	COG2828	Protein conserved in bacteria
K6I41_RS03600	COG0142	geranyltranstransferase activity
K6I41_RS03605	COG2315	Protein conserved in bacteria
K6I41_RS03620	COG1752	Esterase of the alpha-beta hydrolase superfamily
K6I41_RS03645	COG2194	sulfuric ester hydrolase activity
K6I41_RS03650	COG0745	RESPONSE REGULATOR receiver
K6I41_RS03655	COG0642	Histidine kinase
K6I41_RS03665	COG0004	ammonium transporteR
K6I41_RS03670	COG0583	DNA-binding transcription factor activity
K6I41_RS03700	COG0525	valine-tRNA ligase activity
K6I41_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS03720	COG0393	Putative heavy-metal-binding
K6I41_RS03725	COG0393	Putative heavy-metal-binding
K6I41_RS03730	COG1538	Outer membrane efflux protein
K6I41_RS03740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6I41_RS03745	COG0671	phosphoesterase, PA-phosphatase related
K6I41_RS03770	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K6I41_RS03785	COG1648	precorrin-2 dehydrogenase activity
K6I41_RS03785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K6I41_RS03790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K6I41_RS03825	COG0531	amino acid
K6I41_RS03840	COG0321	lipoyl(octanoyl) transferase activity
K6I41_RS03845	COG2921	Belongs to the UPF0250 family
K6I41_RS03885	COG2009	succinate dehydrogenase
K6I41_RS03890	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K6I41_RS03895	COG1053	succinate dehydrogenase
K6I41_RS03900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K6I41_RS03925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6I41_RS03945	COG2354	Protein conserved in bacteria
K6I41_RS03950	COG2321	neutral zinc metallopeptidase
K6I41_RS03970	COG2843	Capsule synthesis protein
K6I41_RS03985	COG0589	response to stress
K6I41_RS03990	COG0110	maltose O-acetyltransferase activity
K6I41_RS04005	COG0505	Belongs to the CarA family
K6I41_RS04035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K6I41_RS04040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K6I41_RS04085	COG0477	Major facilitator Superfamily
K6I41_RS04090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K6I41_RS04105	COG1597	lipid kinase activity
K6I41_RS04110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K6I41_RS04135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K6I41_RS04140	COG0584	glycerophosphoryl diester phosphodiesterase
K6I41_RS04160	COG0741	lytic transglycosylase activity
K6I41_RS04180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K6I41_RS04200	COG0583	DNA-binding transcription factor activity
K6I41_RS04205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K6I41_RS04230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6I41_RS04240	COG0778	Nitroreductase
K6I41_RS04255	COG1929	Belongs to the glycerate kinase type-1 family
K6I41_RS04265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K6I41_RS04295	COG1113	amino acid transport
K6I41_RS04305	COG0019	diaminopimelate decarboxylase activity
K6I41_RS04320	COG1280	lysine exporter protein (LysE YggA)
K6I41_RS04325	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K6I41_RS04350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K6I41_RS04370	COG0463	Glycosyl transferase, family 2
K6I41_RS04390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6I41_RS04415	COG0697	spore germination
K6I41_RS04425	COG4591	ABC-type transport system involved in lipoprotein release permease component
K6I41_RS04430	COG1136	(ABC) transporter
K6I41_RS04435	COG2333	competence protein COMEC
K6I41_RS04435	COG0658	competence protein
K6I41_RS04445	COG0616	signal peptide processing
K6I41_RS04445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K6I41_RS04455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K6I41_RS04465	COG0628	permease
K6I41_RS04500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K6I41_RS04520	COG0823	Involved in the tonB-independent uptake of proteins
K6I41_RS04540	COG0824	Thioesterase
K6I41_RS04545	COG1473	amidohydrolase
K6I41_RS04565	COG0047	phosphoribosylformylglycinamidine synthase activity
K6I41_RS04565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K6I41_RS04570	COG2814	Major facilitator Superfamily
K6I41_RS04575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K6I41_RS04580	COG1024	Enoyl-CoA hydratase
K6I41_RS04585	COG1051	belongs to the nudix hydrolase family
K6I41_RS04585	COG1056	cytidyltransferase-related domain
K6I41_RS04610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K6I41_RS04625	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K6I41_RS04630	COG0602	queuosine metabolic process
K6I41_RS04640	COG4625	pathogenesis
K6I41_RS04645	COG0583	DNA-binding transcription factor activity
K6I41_RS04650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K6I41_RS04655	COG4208	sulfate ABC transporter
K6I41_RS04660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K6I41_RS04670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K6I41_RS04675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K6I41_RS04680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K6I41_RS04700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K6I41_RS04710	COG0481	GTPase activity
K6I41_RS04715	COG0681	Belongs to the peptidase S26 family
K6I41_RS04725	COG0571	ribonuclease III activity
K6I41_RS04730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K6I41_RS04745	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K6I41_RS04755	COG4221	oxidoreductase activity
K6I41_RS04785	COG0436	Aminotransferase
K6I41_RS04805	COG0556	nucleotide-excision repair
K6I41_RS04860	COG2070	2-Nitropropane dioxygenase
K6I41_RS04875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K6I41_RS04890	COG1215	transferase activity, transferring glycosyl groups
K6I41_RS04905	COG0415	Belongs to the DNA photolyase family
K6I41_RS04915	COG1252	NADH dehydrogenase
K6I41_RS04920	COG1686	Belongs to the peptidase S11 family
K6I41_RS04935	COG1187	pseudouridine synthase activity
K6I41_RS04950	COG0477	Major facilitator Superfamily
K6I41_RS04955	COG0583	DNA-binding transcription factor activity
K6I41_RS04960	COG1823	symporter activity
K6I41_RS04970	COG0612	Peptidase, M16
K6I41_RS05005	COG0352	thiamine-phosphate diphosphorylase activity
K6I41_RS05040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6I41_RS05065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K6I41_RS05070	COG0076	glutamate decarboxylase activity
K6I41_RS05080	COG1522	sequence-specific DNA binding
K6I41_RS05085	COG3961	Belongs to the TPP enzyme family
K6I41_RS05090	COG1113	amino acid transport
K6I41_RS05095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K6I41_RS05100	COG0573	inorganic phosphate transmembrane transporter activity
K6I41_RS05110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K6I41_RS05115	COG0616	signal peptide processing
K6I41_RS05155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K6I41_RS05160	COG1686	Belongs to the peptidase S11 family
K6I41_RS05185	COG0583	DNA-binding transcription factor activity
K6I41_RS05190	COG1067	ATP-dependent peptidase activity
K6I41_RS05230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K6I41_RS05235	COG1966	Carbon starvation protein
K6I41_RS05240	COG2879	small protein
K6I41_RS05255	COG1024	Enoyl-CoA hydratase
K6I41_RS05265	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS05275	COG0318	PFAM AMP-dependent synthetase and ligase
K6I41_RS05355	COG2423	ornithine cyclodeaminase activity
K6I41_RS05375	COG1741	Belongs to the pirin family
K6I41_RS05390	COG3739	integral membrane protein
K6I41_RS05410	COG0302	gtp cyclohydrolase
K6I41_RS05420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K6I41_RS05455	COG0512	Glutamine amidotransferase of anthranilate synthase
K6I41_RS05470	COG0174	glutamine synthetase
K6I41_RS05480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K6I41_RS05515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K6I41_RS05520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K6I41_RS05525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K6I41_RS05535	COG0281	malic enzyme
K6I41_RS05535	COG0280	phosphate acetyltransferase
K6I41_RS05545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K6I41_RS05550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K6I41_RS05555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K6I41_RS05570	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS05575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K6I41_RS05580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6I41_RS05590	COG2223	nitrite transmembrane transporter activity
K6I41_RS05600	COG0024	Methionine aminopeptidase
K6I41_RS05605	COG0052	Belongs to the universal ribosomal protein uS2 family
K6I41_RS05620	COG2207	Transcriptional regulator
K6I41_RS05645	COG2951	lytic endotransglycosylase activity
K6I41_RS05650	COG0772	Belongs to the SEDS family
K6I41_RS05665	COG0842	Transport permease protein
K6I41_RS05670	COG1131	(ABC) transporter
K6I41_RS05715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6I41_RS05730	COG4215	(ABC) transporter
K6I41_RS05735	COG4160	amino acid transport
K6I41_RS05740	COG4598	ABC transporter
K6I41_RS05750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K6I41_RS05755	COG0826	peptidase U32
K6I41_RS05760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6I41_RS05765	COG0384	phenazine biosynthesis protein PhzF
K6I41_RS05775	COG1720	tRNA m6t6A37 methyltransferase activity
K6I41_RS05785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K6I41_RS05800	COG0642	Histidine kinase
K6I41_RS05810	COG0494	nUDIX hydrolase
K6I41_RS05820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K6I41_RS05825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K6I41_RS05830	COG3139	Protein of unknown function (DUF1315)
K6I41_RS05840	COG1301	dicarboxylic acid transport
K6I41_RS05845	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS05855	COG2819	hydrolase of the alpha beta superfamily
K6I41_RS05865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K6I41_RS05875	COG2195	Cleaves the N-terminal amino acid of tripeptides
K6I41_RS05895	COG1690	Belongs to the RtcB family
K6I41_RS05900	COG1234	tRNA 3'-trailer cleavage
K6I41_RS05905	COG4650	regulator
K6I41_RS05930	COG2363	Small membrane protein
K6I41_RS05955	COG0513	Belongs to the DEAD box helicase family
K6I41_RS05965	COG0778	Nitroreductase
K6I41_RS05995	COG1286	toxin biosynthetic process
K6I41_RS06020	COG4783	chaperone-mediated protein folding
K6I41_RS06025	COG1610	YqeY-like protein
K6I41_RS06055	COG0515	serine threonine protein kinase
K6I41_RS06055	COG2815	serine threonine protein kinase
K6I41_RS06080	COG1278	Cold shock
K6I41_RS06100	COG0786	glutamate:sodium symporter activity
K6I41_RS06105	COG0475	glutathione-regulated potassium exporter activity
K6I41_RS06105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K6I41_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS06140	COG2985	domain, Protein
K6I41_RS06150	COG2995	paraquat-inducible protein a
K6I41_RS06155	COG3008	intermembrane lipid transfer
K6I41_RS06155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K6I41_RS06165	COG2351	hydroxyisourate hydrolase activity
K6I41_RS06205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K6I41_RS06215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K6I41_RS06220	COG0642	Histidine kinase
K6I41_RS06225	COG0745	RESPONSE REGULATOR receiver
K6I41_RS06240	COG1794	racemase activity, acting on amino acids and derivatives
K6I41_RS06250	COG2175	clavaminate synthase activity
K6I41_RS06255	COG3246	L-lysine catabolic process to acetate
K6I41_RS06260	COG2814	Major facilitator Superfamily
K6I41_RS06275	COG2855	membrane
K6I41_RS06310	COG2814	Major facilitator Superfamily
K6I41_RS06325	COG0625	glutathione transferase activity
K6I41_RS06340	COG1301	dicarboxylic acid transport
K6I41_RS06355	COG2011	ABC-type metal ion transport system permease component
K6I41_RS06360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K6I41_RS06365	COG1464	Belongs to the NlpA lipoprotein family
K6I41_RS06370	COG0151	Belongs to the GarS family
K6I41_RS06380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K6I41_RS06410	COG2308	Evidence 4 Homologs of previously reported genes of
K6I41_RS06420	COG1305	Transglutaminase-like
K6I41_RS06430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K6I41_RS06435	COG0305	Participates in initiation and elongation during chromosome replication
K6I41_RS06460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K6I41_RS06470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K6I41_RS06475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K6I41_RS06500	COG0726	polysaccharide deacetylase
K6I41_RS06500	COG1649	PFAM Uncharacterised BCR, COG1649
K6I41_RS06505	COG1215	transferase activity, transferring glycosyl groups
K6I41_RS06510	COG3658	cytochrome
K6I41_RS06520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6I41_RS06545	COG2890	protein-(glutamine-N5) methyltransferase activity
K6I41_RS06550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS06555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6I41_RS06570	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS06575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K6I41_RS06590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K6I41_RS06600	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K6I41_RS06605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K6I41_RS06610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K6I41_RS06615	COG2205	protein histidine kinase activity
K6I41_RS06620	COG0745	RESPONSE REGULATOR receiver
K6I41_RS06625	COG0174	glutamine synthetase
K6I41_RS06640	COG0477	Major facilitator Superfamily
K6I41_RS06645	COG0729	surface antigen
K6I41_RS06675	COG0471	metal ion transport
K6I41_RS06685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6I41_RS06690	COG2814	Major facilitator Superfamily
K6I41_RS06705	COG0583	DNA-binding transcription factor activity
K6I41_RS06720	COG1187	pseudouridine synthase activity
K6I41_RS06740	COG0802	atpase or kinase
K6I41_RS06745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K6I41_RS06755	COG1923	regulation of RNA biosynthetic process
K6I41_RS06760	COG0697	spore germination
K6I41_RS06785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K6I41_RS06795	COG0519	Catalyzes the synthesis of GMP from XMP
K6I41_RS06795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K6I41_RS06800	COG4302	ethanolamine ammonia-lyase activity
K6I41_RS06805	COG4303	Ethanolamine ammonia lyase large subunit
K6I41_RS06810	COG0531	amino acid
K6I41_RS06830	COG1454	alcohol dehydrogenase
K6I41_RS06835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K6I41_RS06845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
K6I41_RS06865	COG0308	aminopeptidase N
K6I41_RS06905	COG1605	Chorismate mutase
K6I41_RS06920	COG4772	TonB-dependent receptor
K6I41_RS06970	COG1733	regulation of RNA biosynthetic process
K6I41_RS06990	COG0583	DNA-binding transcription factor activity
K6I41_RS07005	COG3111	PFAM Bacterial OB fold (BOF) protein
K6I41_RS07025	COG0488	(ABC) transporter
K6I41_RS07030	COG0589	response to stress
K6I41_RS07050	COG3135	benzoate transporter
K6I41_RS07055	COG1522	sequence-specific DNA binding
K6I41_RS07065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K6I41_RS07070	COG0583	DNA-binding transcription factor activity
K6I41_RS07080	COG0183	Belongs to the thiolase family
K6I41_RS07085	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS07090	COG2030	dehydratase
K6I41_RS07095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K6I41_RS07120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K6I41_RS07130	COG0824	Thioesterase
K6I41_RS07135	COG1454	alcohol dehydrogenase
K6I41_RS07155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K6I41_RS07185	COG0069	glutamate synthase activity
K6I41_RS07215	COG2814	Major facilitator Superfamily
K6I41_RS07230	COG0511	ligase activity, forming carbon-carbon bonds
K6I41_RS07255	COG4264	IucA IucC family
K6I41_RS07265	COG4264	IucA IucC family
K6I41_RS07270	COG2423	ornithine cyclodeaminase activity
K6I41_RS07275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K6I41_RS07285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6I41_RS07285	COG1116	anion transmembrane transporter activity
K6I41_RS07290	COG0745	RESPONSE REGULATOR receiver
K6I41_RS07300	COG2146	nitrite reductase [NAD(P)H] activity
K6I41_RS07300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6I41_RS07305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6I41_RS07310	COG0243	molybdopterin cofactor binding
K6I41_RS07320	COG0243	molybdopterin cofactor binding
K6I41_RS07325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K6I41_RS07340	COG0521	Mo-molybdopterin cofactor biosynthetic process
K6I41_RS07340	COG0315	cyclic pyranopterin monophosphate synthase activity
K6I41_RS07345	COG0303	'Molybdopterin
K6I41_RS07355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6I41_RS07360	COG0697	spore germination
K6I41_RS07385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K6I41_RS07400	COG1335	isochorismatase
K6I41_RS07440	COG2204	response regulator
K6I41_RS07445	COG3852	Histidine kinase
K6I41_RS07470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K6I41_RS07475	COG0575	Belongs to the CDS family
K6I41_RS07490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6I41_RS07510	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6I41_RS07525	COG2137	regulation of response to DNA damage stimulus
K6I41_RS07535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K6I41_RS07540	COG1011	Hydrolase
K6I41_RS07555	COG1522	sequence-specific DNA binding
K6I41_RS07565	COG1113	amino acid transport
K6I41_RS07590	COG0659	secondary active sulfate transmembrane transporter activity
K6I41_RS07610	COG3300	MHYT domain
K6I41_RS07610	COG5001	Diguanylate cyclase
K6I41_RS07625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K6I41_RS07625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K6I41_RS07625	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
K6I41_RS07630	COG1105	Belongs to the carbohydrate kinase PfkB family
K6I41_RS07635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6I41_RS07635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K6I41_RS07665	COG0024	Methionine aminopeptidase
K6I41_RS07670	COG0583	DNA-binding transcription factor activity
K6I41_RS07685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K6I41_RS07690	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K6I41_RS07690	COG0517	IMP dehydrogenase activity
K6I41_RS07715	COG0552	protein localization to endoplasmic reticulum
K6I41_RS07740	COG4890	Cyd operon protein YbgT
K6I41_RS07745	COG1294	oxidase, subunit
K6I41_RS07760	COG1585	Membrane protein implicated in regulation of membrane protease activity
K6I41_RS07770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6I41_RS07775	COG4774	siderophore transport
K6I41_RS07790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6I41_RS07795	COG0569	domain protein
K6I41_RS07800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K6I41_RS07830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K6I41_RS07835	COG0542	response to heat
K6I41_RS07845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K6I41_RS07860	COG1902	pentaerythritol trinitrate reductase activity
K6I41_RS07860	COG0446	pyridine nucleotide-disulphide oxidoreductase
K6I41_RS07900	COG0148	phosphopyruvate hydratase activity
K6I41_RS07905	COG2323	membrane
K6I41_RS07920	COG4773	Receptor
K6I41_RS07930	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
K6I41_RS07940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K6I41_RS07945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K6I41_RS07950	COG0183	Belongs to the thiolase family
K6I41_RS07955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K6I41_RS07960	COG0596	Alpha beta hydrolase
K6I41_RS07965	COG2271	Major facilitator Superfamily
K6I41_RS07970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K6I41_RS07975	COG3485	protocatechuate 3,4-dioxygenase
K6I41_RS07980	COG3485	protocatechuate 3,4-dioxygenase
K6I41_RS07985	COG0710	3-dehydroquinate dehydratase activity
K6I41_RS07990	COG3420	alginic acid biosynthetic process
K6I41_RS07995	COG3659	wide pore channel activity
K6I41_RS08000	COG4993	Dehydrogenase
K6I41_RS08010	COG2391	methyltransferase activity
K6I41_RS08025	COG1414	Transcriptional regulator
K6I41_RS08030	COG0583	DNA-binding transcription factor activity
K6I41_RS08035	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS08060	COG2814	Major facilitator Superfamily
K6I41_RS08070	COG0154	amidase activity
K6I41_RS08090	COG4638	Rieske (2fe-2S)
K6I41_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS08110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K6I41_RS08120	COG3733	amine oxidase
K6I41_RS08135	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS08140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K6I41_RS08145	COG0183	Belongs to the thiolase family
K6I41_RS08150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K6I41_RS08155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K6I41_RS08165	COG4829	muconolactone delta-isomerase
K6I41_RS08170	COG4948	Mandelate Racemase Muconate Lactonizing
K6I41_RS08175	COG0583	DNA-binding transcription factor activity
K6I41_RS08185	COG2186	Transcriptional regulator
K6I41_RS08205	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS08215	COG2351	hydroxyisourate hydrolase activity
K6I41_RS08220	COG2233	PERMEase
K6I41_RS08230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6I41_RS08235	COG2186	Transcriptional regulator
K6I41_RS08245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6I41_RS08255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS08265	COG0583	DNA-binding transcription factor activity
K6I41_RS08270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6I41_RS08275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6I41_RS08300	COG1079	Belongs to the binding-protein-dependent transport system permease family
K6I41_RS08320	COG3829	transcription factor binding
K6I41_RS08330	COG3829	transcription factor binding
K6I41_RS08335	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS08340	COG1414	Transcriptional regulator
K6I41_RS08345	COG1053	succinate dehydrogenase
K6I41_RS08360	COG3659	wide pore channel activity
K6I41_RS08365	COG1309	transcriptional regulator
K6I41_RS08370	COG0477	Major facilitator Superfamily
K6I41_RS08385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K6I41_RS08395	COG1053	succinate dehydrogenase
K6I41_RS08400	COG1053	succinate dehydrogenase
K6I41_RS08430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K6I41_RS08465	COG1309	transcriptional regulator
K6I41_RS08480	COG4689	acetoacetate decarboxylase
K6I41_RS08490	COG1902	pentaerythritol trinitrate reductase activity
K6I41_RS08500	COG3321	synthase
K6I41_RS08500	COG4221	oxidoreductase activity
K6I41_RS08500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K6I41_RS08500	COG0604	alcohol dehydrogenase
K6I41_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS08525	COG0318	PFAM AMP-dependent synthetase and ligase
K6I41_RS08550	COG1902	pentaerythritol trinitrate reductase activity
K6I41_RS08560	COG1733	regulation of RNA biosynthetic process
K6I41_RS08565	COG0702	epimerase
K6I41_RS08575	COG0583	DNA-binding transcription factor activity
K6I41_RS08590	COG1309	transcriptional regulator
K6I41_RS08685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K6I41_RS08690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K6I41_RS08735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6I41_RS08750	COG2271	Major facilitator Superfamily
K6I41_RS08760	COG1566	PFAM secretion protein HlyD family protein
K6I41_RS08775	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS08780	COG0129	dihydroxy-acid dehydratase activity
K6I41_RS08790	COG0583	DNA-binding transcription factor activity
K6I41_RS08795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6I41_RS08805	COG2084	Dehydrogenase
K6I41_RS08810	COG2207	Transcriptional regulator
K6I41_RS08815	COG1064	alcohol dehydrogenase
K6I41_RS08835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6I41_RS08840	COG1120	ATPase activity
K6I41_RS08860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K6I41_RS08895	COG2197	response regulator
K6I41_RS08935	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K6I41_RS08985	COG1414	Transcriptional regulator
K6I41_RS08990	COG2851	Citrate transporter
K6I41_RS09000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K6I41_RS09005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K6I41_RS09025	COG2259	Doxx family
K6I41_RS09030	COG0583	DNA-binding transcription factor activity
K6I41_RS09035	COG2205	protein histidine kinase activity
K6I41_RS09040	COG0745	RESPONSE REGULATOR receiver
K6I41_RS09045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6I41_RS09050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6I41_RS09065	COG4628	conserved protein (DUF2132)
K6I41_RS09075	COG2175	clavaminate synthase activity
K6I41_RS09080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6I41_RS09095	COG0667	Aldo Keto reductase
K6I41_RS09100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6I41_RS09115	COG2175	clavaminate synthase activity
K6I41_RS09145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS09150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6I41_RS09155	COG4771	TonB-dependent receptor
K6I41_RS09185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6I41_RS09190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6I41_RS09195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS09200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS09215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K6I41_RS09220	COG0805	protein transport
K6I41_RS09230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6I41_RS09250	COG1132	(ABC) transporter
K6I41_RS09255	COG1132	(ABC) transporter
K6I41_RS09275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K6I41_RS09280	COG0601	transmembrane transport
K6I41_RS09310	COG3539	Fimbrial protein
K6I41_RS09335	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K6I41_RS09345	COG0753	catalase activity
K6I41_RS09365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K6I41_RS09420	COG4771	TonB-dependent receptor
K6I41_RS09425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6I41_RS09430	COG3433	isochorismatase activity
K6I41_RS09430	COG1535	isochorismatase
K6I41_RS09440	COG1021	2,3-dihydroxybenzoate-AMP ligase
K6I41_RS09445	COG1169	isochorismate synthase
K6I41_RS09450	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS09460	COG3251	PFAM MbtH domain protein
K6I41_RS09465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K6I41_RS09490	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K6I41_RS09495	COG4149	molybdate abc transporter
K6I41_RS09500	COG0725	ABC transporter, periplasmic molybdate-binding protein
K6I41_RS09510	COG4638	Rieske (2fe-2S)
K6I41_RS09515	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
K6I41_RS09520	COG0543	2 iron, 2 sulfur cluster binding
K6I41_RS09520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6I41_RS09535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K6I41_RS09545	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS09565	COG2207	Transcriptional regulator
K6I41_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS09575	COG2610	gluconate transmembrane transporter activity
K6I41_RS09635	COG0583	DNA-binding transcription factor activity
K6I41_RS09650	COG2031	fatty acid transporter
K6I41_RS09655	COG0183	Belongs to the thiolase family
K6I41_RS09660	COG0583	DNA-binding transcription factor activity
K6I41_RS09665	COG0583	DNA-binding transcription factor activity
K6I41_RS09680	COG1027	Aspartate ammonia-lyase
K6I41_RS09690	COG0477	Major facilitator Superfamily
K6I41_RS09710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS09715	COG4521	taurine ABC transporter
K6I41_RS09730	COG2188	Transcriptional regulator
K6I41_RS09735	COG2207	Transcriptional regulator
K6I41_RS09735	COG3708	Transcriptional regulator
K6I41_RS09750	COG0730	response to heat
K6I41_RS09775	COG3781	membrane
K6I41_RS09780	COG1063	alcohol dehydrogenase
K6I41_RS09790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6I41_RS09795	COG0508	dehydrogenase complex catalyzes the overall conversion of
K6I41_RS09800	COG0022	dehydrogenase e1 component
K6I41_RS09805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K6I41_RS09810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K6I41_RS09825	COG3706	GGDEF domain
K6I41_RS09845	COG0133	tryptophan synthase activity
K6I41_RS09855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K6I41_RS09885	COG0583	DNA-binding transcription factor activity
K6I41_RS09890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K6I41_RS09900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K6I41_RS09965	COG0842	Transport permease protein
K6I41_RS09970	COG0842	Transport permease protein
K6I41_RS09975	COG1131	(ABC) transporter
K6I41_RS09990	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6I41_RS09995	COG4773	Receptor
K6I41_RS10020	COG0730	response to heat
K6I41_RS10025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K6I41_RS10040	COG0406	alpha-ribazole phosphatase activity
K6I41_RS10045	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K6I41_RS10065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K6I41_RS10080	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS10085	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS10090	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6I41_RS10095	COG2207	Transcriptional regulator
K6I41_RS10100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6I41_RS10105	COG0776	regulation of translation
K6I41_RS10130	COG0822	iron-sulfur transferase activity
K6I41_RS10135	COG0316	Belongs to the HesB IscA family
K6I41_RS10165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K6I41_RS10185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K6I41_RS10190	COG0702	epimerase
K6I41_RS10230	COG0601	transmembrane transport
K6I41_RS10235	COG0339	signal peptide processing
K6I41_RS10240	COG4166	transmembrane transport
K6I41_RS10255	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K6I41_RS10280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K6I41_RS10285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K6I41_RS10300	COG2431	L-lysine efflux transmembrane transporter activity
K6I41_RS10315	COG0776	regulation of translation
K6I41_RS10380	COG0084	hydrolase, TatD family'
K6I41_RS10400	COG1663	tetraacyldisaccharide 4'-kinase activity
K6I41_RS10405	COG1132	(ABC) transporter
K6I41_RS10415	COG0811	peptide transport
K6I41_RS10420	COG1475	DNA binding
K6I41_RS10425	COG1192	Involved in chromosome partitioning
K6I41_RS10435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K6I41_RS10450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6I41_RS10455	COG0191	fructose-bisphosphate aldolase activity
K6I41_RS10475	COG0424	maF-like protein
K6I41_RS10480	COG2850	peptidyl-arginine hydroxylation
K6I41_RS10490	COG0640	Transcriptional regulator
K6I41_RS10500	COG3619	membrane
K6I41_RS10505	COG3122	Protein conserved in bacteria
K6I41_RS10510	COG1132	(ABC) transporter
K6I41_RS10530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K6I41_RS10535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6I41_RS10545	COG0506	proline dehydrogenase activity
K6I41_RS10545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K6I41_RS10545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K6I41_RS10550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K6I41_RS10565	COG3698	Phosphodiester glycosidase
K6I41_RS10575	COG2353	YceI-like domain
K6I41_RS10585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K6I41_RS10630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K6I41_RS10630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K6I41_RS10655	COG3539	Fimbrial protein
K6I41_RS10690	COG0583	DNA-binding transcription factor activity
K6I41_RS10695	COG0697	spore germination
K6I41_RS10705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K6I41_RS10715	COG0583	DNA-binding transcription factor activity
K6I41_RS10730	COG1309	transcriptional regulator
K6I41_RS10745	COG1522	sequence-specific DNA binding
K6I41_RS10755	COG1126	abc transporter atp-binding protein
K6I41_RS10760	COG0765	amino acid transport
K6I41_RS10765	COG0765	amino acid transport
K6I41_RS10795	COG1464	Belongs to the NlpA lipoprotein family
K6I41_RS10805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K6I41_RS10810	COG2011	ABC-type metal ion transport system permease component
K6I41_RS10815	COG0012	GTP binding
K6I41_RS10840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K6I41_RS10875	COG2207	Transcriptional regulator
K6I41_RS10875	COG1917	Cupin 2, conserved barrel domain protein
K6I41_RS10880	COG0386	Belongs to the glutathione peroxidase family
K6I41_RS10890	COG0436	Aminotransferase
K6I41_RS10895	COG1301	dicarboxylic acid transport
K6I41_RS10930	COG3634	alkyl hydroperoxide reductase activity
K6I41_RS10945	COG0583	DNA-binding transcription factor activity
K6I41_RS10950	COG0431	NADPH-dependent FMN reductase
K6I41_RS10955	COG0798	PFAM Bile acid sodium symporter
K6I41_RS10965	COG0640	Transcriptional regulator
K6I41_RS10980	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K6I41_RS10990	COG0583	DNA-binding transcription factor activity
K6I41_RS11000	COG1953	Uracil, thiamine, allantoin
K6I41_RS11010	COG2175	clavaminate synthase activity
K6I41_RS11015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS11020	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K6I41_RS11025	COG4521	taurine ABC transporter
K6I41_RS11035	COG0477	Major facilitator Superfamily
K6I41_RS11055	COG1271	oxidase subunit
K6I41_RS11060	COG1294	oxidase, subunit
K6I41_RS11070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6I41_RS11090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K6I41_RS11110	COG3052	prosthetic group binding
K6I41_RS11115	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
K6I41_RS11125	COG2814	Major facilitator Superfamily
K6I41_RS11145	COG1346	cytolysis
K6I41_RS11155	COG0583	DNA-binding transcription factor activity
K6I41_RS11160	COG0625	glutathione transferase activity
K6I41_RS11165	COG0625	glutathione transferase activity
K6I41_RS11185	COG0583	DNA-binding transcription factor activity
K6I41_RS11200	COG1045	serine acetyltransferase
K6I41_RS11205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6I41_RS11210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K6I41_RS11220	COG1280	lysine exporter protein (LysE YggA)
K6I41_RS11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6I41_RS11240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6I41_RS11250	COG0765	amino acid transport
K6I41_RS11255	COG0765	amino acid transport
K6I41_RS11295	COG0784	Response regulator, receiver
K6I41_RS11295	COG2205	protein histidine kinase activity
K6I41_RS11315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K6I41_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS11385	COG0583	DNA-binding transcription factor activity
K6I41_RS11395	COG2814	Major facilitator Superfamily
K6I41_RS11410	COG0318	PFAM AMP-dependent synthetase and ligase
K6I41_RS11415	COG1309	transcriptional regulator
K6I41_RS11420	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS11425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K6I41_RS11430	COG1024	Enoyl-CoA hydratase
K6I41_RS11435	COG4770	biotin carboxylase activity
K6I41_RS11445	COG0583	DNA-binding transcription factor activity
K6I41_RS11460	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS11470	COG2814	Major facilitator Superfamily
K6I41_RS11480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K6I41_RS11485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K6I41_RS11490	COG2814	Major facilitator Superfamily
K6I41_RS11495	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS11500	COG1024	Enoyl-CoA hydratase
K6I41_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS11510	COG1250	3-hydroxyacyl-CoA dehydrogenase
K6I41_RS11515	COG0183	Belongs to the thiolase family
K6I41_RS11535	COG2192	nodulation
K6I41_RS11550	COG1024	Enoyl-CoA hydratase
K6I41_RS11560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K6I41_RS11565	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS11570	COG2814	Major facilitator Superfamily
K6I41_RS11575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K6I41_RS11580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K6I41_RS11595	COG3842	ATPase activity
K6I41_RS11600	COG1840	ABC-type Fe3 transport system, periplasmic component
K6I41_RS11610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6I41_RS11615	COG1414	Transcriptional regulator
K6I41_RS11625	COG0583	DNA-binding transcription factor activity
K6I41_RS11640	COG0406	alpha-ribazole phosphatase activity
K6I41_RS11650	COG1760	l-serine dehydratase
K6I41_RS11655	COG0531	amino acid
K6I41_RS11660	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS11685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K6I41_RS11705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6I41_RS11720	COG0789	Transcriptional regulator
K6I41_RS11730	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K6I41_RS11735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6I41_RS11750	COG2807	transmembrane transport
K6I41_RS11755	COG0590	tRNA wobble adenosine to inosine editing
K6I41_RS11760	COG0666	response to abiotic stimulus
K6I41_RS11810	COG2885	chlorophyll binding
K6I41_RS11880	COG3209	COG3209 Rhs family protein
K6I41_RS11905	COG0477	Major facilitator Superfamily
K6I41_RS11920	COG1116	anion transmembrane transporter activity
K6I41_RS11925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6I41_RS11935	COG0864	Transcriptional regulator
K6I41_RS11945	COG1733	regulation of RNA biosynthetic process
K6I41_RS11950	COG2249	NAD(P)H dehydrogenase (quinone) activity
K6I41_RS11955	COG0439	Biotin carboxylase
K6I41_RS11970	COG1063	alcohol dehydrogenase
K6I41_RS11975	COG1250	3-hydroxyacyl-CoA dehydrogenase
K6I41_RS12035	COG0038	chloride channel
K6I41_RS12040	COG4770	biotin carboxylase activity
K6I41_RS12060	COG1914	H( )-stimulated, divalent metal cation uptake system
K6I41_RS12070	COG0300	oxidoreductase activity
K6I41_RS12085	COG0300	oxidoreductase activity
K6I41_RS12090	COG2072	flavoprotein involved in K transport
K6I41_RS12135	COG1309	transcriptional regulator
K6I41_RS12145	COG1073	alpha beta
K6I41_RS12150	COG1073	alpha beta
K6I41_RS12165	COG1309	transcriptional regulator
K6I41_RS12180	COG0657	acetylesterase activity
K6I41_RS12195	COG1595	DNA-templated transcription, initiation
K6I41_RS12200	COG3712	iron ion homeostasis
K6I41_RS12225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K6I41_RS12230	COG4774	siderophore transport
K6I41_RS12255	COG4521	taurine ABC transporter
K6I41_RS12260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS12265	COG1116	anion transmembrane transporter activity
K6I41_RS12270	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K6I41_RS12280	COG3038	cytochrome b561
K6I41_RS12285	COG0753	catalase activity
K6I41_RS12300	COG1278	Cold shock
K6I41_RS12335	COG1522	sequence-specific DNA binding
K6I41_RS12340	COG0531	amino acid
K6I41_RS12345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K6I41_RS12360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K6I41_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS12460	COG2050	protein possibly involved in aromatic compounds catabolism
K6I41_RS12470	COG3327	negative regulation of DNA-templated transcription, initiation
K6I41_RS12475	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K6I41_RS12480	COG0183	Belongs to the thiolase family
K6I41_RS12485	COG1250	3-hydroxyacyl-CoA dehydrogenase
K6I41_RS12490	COG1024	Enoyl-CoA hydratase
K6I41_RS12495	COG1024	Enoyl-CoA hydratase
K6I41_RS12500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6I41_RS12505	COG2151	metal-sulfur cluster biosynthetic enzyme
K6I41_RS12510	COG3396	Phenylacetate-CoA oxygenase
K6I41_RS12515	COG3460	Phenylacetate-CoA oxygenase
K6I41_RS12520	COG3396	Phenylacetate-CoA oxygenase
K6I41_RS12525	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS12525	COG2030	dehydratase
K6I41_RS12555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K6I41_RS12565	COG4122	O-methyltransferase activity
K6I41_RS12600	COG1137	ATPase activity
K6I41_RS12605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K6I41_RS12615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
K6I41_RS12640	COG1476	TRANSCRIPTIONal
K6I41_RS12690	COG1714	RDD family
K6I41_RS12720	COG2814	Major facilitator Superfamily
K6I41_RS12735	COG0668	transmembrane transport
K6I41_RS12800	COG2226	methyltransferase
K6I41_RS12825	COG1278	Cold shock
K6I41_RS12830	COG1560	Kdo2-lipid A biosynthetic process
K6I41_RS12835	COG1280	lysine exporter protein (LysE YggA)
K6I41_RS12870	COG1570	exodeoxyribonuclease VII activity
K6I41_RS12900	COG3791	Glutathione-dependent formaldehyde-activating
K6I41_RS12955	COG2871	sodium ion transport
K6I41_RS12965	COG0583	DNA-binding transcription factor activity
K6I41_RS12975	COG4638	Rieske (2fe-2S)
K6I41_RS12985	COG0543	2 iron, 2 sulfur cluster binding
K6I41_RS12985	COG0633	Ferredoxin
K6I41_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS12995	COG3135	benzoate transporter
K6I41_RS13000	COG2814	Major facilitator Superfamily
K6I41_RS13015	COG1643	Atp-dependent helicase
K6I41_RS13030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6I41_RS13050	COG3634	alkyl hydroperoxide reductase activity
K6I41_RS13070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K6I41_RS13075	COG0625	glutathione transferase activity
K6I41_RS13085	COG2885	chlorophyll binding
K6I41_RS13120	COG0542	response to heat
K6I41_RS13135	COG1765	OsmC-like protein
K6I41_RS13150	COG0667	Aldo Keto reductase
K6I41_RS13165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K6I41_RS13180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K6I41_RS13190	COG0527	aspartate kinase activity
K6I41_RS13200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K6I41_RS13210	COG3038	cytochrome b561
K6I41_RS13215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K6I41_RS13220	COG2252	PERMEase
K6I41_RS13230	COG1741	Belongs to the pirin family
K6I41_RS13235	COG1309	transcriptional regulator
K6I41_RS13250	COG2072	flavoprotein involved in K transport
K6I41_RS13255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K6I41_RS13260	COG0583	DNA-binding transcription factor activity
K6I41_RS13275	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K6I41_RS13305	COG1944	ATP diphosphatase activity
K6I41_RS13325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K6I41_RS13340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6I41_RS13355	COG2814	Major facilitator Superfamily
K6I41_RS13360	COG1024	Enoyl-CoA hydratase
K6I41_RS13365	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS13375	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS13400	COG0697	spore germination
K6I41_RS13420	COG1113	amino acid transport
K6I41_RS13440	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS13460	COG0531	amino acid
K6I41_RS13470	COG1113	amino acid transport
K6I41_RS13480	COG1309	transcriptional regulator
K6I41_RS13485	COG4269	membrane
K6I41_RS13500	COG2207	Transcriptional regulator
K6I41_RS13535	COG0446	pyridine nucleotide-disulphide oxidoreductase
K6I41_RS13535	COG1902	pentaerythritol trinitrate reductase activity
K6I41_RS13545	COG3706	GGDEF domain
K6I41_RS13545	COG4251	negative regulation of phosphorylation
K6I41_RS13545	COG2203	Gaf domain
K6I41_RS13545	COG5001	Diguanylate cyclase
K6I41_RS13555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K6I41_RS13585	COG4172	Belongs to the ABC transporter superfamily
K6I41_RS13590	COG4239	(ABC) transporter, permease
K6I41_RS13595	COG4174	ABC transporter (Permease)
K6I41_RS13600	COG4166	transmembrane transport
K6I41_RS13605	COG0741	lytic transglycosylase activity
K6I41_RS13605	COG1388	LysM domain
K6I41_RS13605	COG1388	LysM domain
K6I41_RS13605	COG0741	lytic transglycosylase activity
K6I41_RS13650	COG0583	DNA-binding transcription factor activity
K6I41_RS13655	COG1279	arginine transmembrane transporter activity
K6I41_RS13665	COG0789	Transcriptional regulator
K6I41_RS13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6I41_RS13680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6I41_RS13685	COG0006	proline dipeptidase activity
K6I41_RS13800	COG0739	heme binding
K6I41_RS13830	COG0758	DNA mediated transformation
K6I41_RS14025	COG2887	Belongs to the helicase family. UvrD subfamily
K6I41_RS14065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K6I41_RS14080	COG3384	dioxygenase
K6I41_RS14090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K6I41_RS14095	COG2878	Part of a membrane complex involved in electron transport
K6I41_RS14100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K6I41_RS14125	COG0768	penicillin binding
K6I41_RS14130	COG0742	ribosomal rna small subunit methyltransferase
K6I41_RS14145	COG0830	nickel cation binding
K6I41_RS14155	COG0804	urea catabolic process
K6I41_RS14180	COG3015	lipoprotein NlpE involved in copper resistance
K6I41_RS14195	COG1253	flavin adenine dinucleotide binding
K6I41_RS14200	COG2851	Citrate transporter
K6I41_RS14250	COG1773	rubredoxin
K6I41_RS14255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6I41_RS14265	COG0583	DNA-binding transcription factor activity
K6I41_RS14295	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
K6I41_RS14300	COG4181	ATPase activity
K6I41_RS14345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K6I41_RS14365	COG0306	phosphate transporter
K6I41_RS14380	COG3958	Transketolase
K6I41_RS14385	COG3959	Transketolase, thiamine diphosphate binding domain
K6I41_RS14390	COG2271	Major facilitator Superfamily
K6I41_RS14395	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS14400	COG0583	DNA-binding transcription factor activity
K6I41_RS14415	COG2223	nitrite transmembrane transporter activity
K6I41_RS14425	COG2066	Belongs to the glutaminase family
K6I41_RS14430	COG0242	peptide deformylase activity
K6I41_RS14435	COG0477	Major facilitator Superfamily
K6I41_RS14445	COG0028	Belongs to the TPP enzyme family
K6I41_RS14460	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS14465	COG2267	carboxylic ester hydrolase activity
K6I41_RS14475	COG2271	Major facilitator Superfamily
K6I41_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS14510	COG1414	Transcriptional regulator
K6I41_RS14530	COG1024	Enoyl-CoA hydratase
K6I41_RS14540	COG1309	transcriptional regulator
K6I41_RS14550	COG1215	transferase activity, transferring glycosyl groups
K6I41_RS14555	COG1649	PFAM Uncharacterised BCR, COG1649
K6I41_RS14555	COG0726	polysaccharide deacetylase
K6I41_RS14565	COG4681	YaeQ
K6I41_RS14575	COG0523	cobalamin synthesis protein
K6I41_RS14585	COG1607	acyl-coa hydrolase
K6I41_RS14595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6I41_RS14600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6I41_RS14605	COG1309	transcriptional regulator
K6I41_RS14630	COG2040	homocysteine
K6I41_RS14635	COG0531	amino acid
K6I41_RS14690	COG1595	DNA-templated transcription, initiation
K6I41_RS14700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6I41_RS14705	COG0477	Major facilitator Superfamily
K6I41_RS14765	COG0405	Gamma-glutamyltransferase
K6I41_RS14770	COG2814	Major facilitator Superfamily
K6I41_RS14775	COG1566	PFAM secretion protein HlyD family protein
K6I41_RS14780	COG2050	protein possibly involved in aromatic compounds catabolism
K6I41_RS14795	COG1090	epimerase
K6I41_RS14815	COG0420	3'-5' exonuclease activity
K6I41_RS14825	COG1968	undecaprenyl-diphosphatase activity
K6I41_RS14845	COG0735	belongs to the Fur family
K6I41_RS14850	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6I41_RS14855	COG2914	Belongs to the UPF0125 (RnfH) family
K6I41_RS14870	COG0121	glutamine amidotransferase
K6I41_RS14885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K6I41_RS14895	COG0210	DNA helicase
K6I41_RS14900	COG2885	chlorophyll binding
K6I41_RS14905	COG0204	Acyl-transferase
K6I41_RS14935	COG1280	lysine exporter protein (LysE YggA)
K6I41_RS14940	COG1674	ftsk spoiiie
K6I41_RS14945	COG0492	ferredoxin-NADP+ reductase activity
K6I41_RS14950	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K6I41_RS14960	COG0456	acetyltransferase
K6I41_RS14980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K6I41_RS14985	COG0049	tRNA binding
K6I41_RS14990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K6I41_RS15005	COG1981	membrane
K6I41_RS15015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K6I41_RS15015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K6I41_RS15035	COG1012	belongs to the aldehyde dehydrogenase family
K6I41_RS15040	COG4638	Rieske (2fe-2S)
K6I41_RS15045	COG0657	acetylesterase activity
K6I41_RS15055	COG0473	3-isopropylmalate dehydrogenase activity
K6I41_RS15060	COG0583	DNA-binding transcription factor activity
K6I41_RS15080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K6I41_RS15120	COG0358	DNA primase activity
K6I41_RS15135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
K6I41_RS15165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K6I41_RS15195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K6I41_RS15205	COG0351	phosphomethylpyrimidine kinase
K6I41_RS15205	COG0352	thiamine-phosphate diphosphorylase activity
K6I41_RS15205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K6I41_RS15210	COG1652	LysM domain
K6I41_RS15235	COG1399	metal-binding, possibly nucleic acid-binding protein
K6I41_RS15240	COG3101	peptidyl-lysine hydroxylation
K6I41_RS15245	COG0009	L-threonylcarbamoyladenylate synthase
K6I41_RS15250	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K6I41_RS15255	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K6I41_RS15270	COG4106	trans-aconitate 2-methyltransferase activity
K6I41_RS15285	COG2226	methyltransferase
K6I41_RS15285	COG0596	Alpha beta hydrolase
K6I41_RS15285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K6I41_RS15295	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K6I41_RS15300	COG2223	nitrite transmembrane transporter activity
K6I41_RS15320	COG1196	nuclear chromosome segregation
K6I41_RS15330	COG0730	response to heat
K6I41_RS15335	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
K6I41_RS15335	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
K6I41_RS15345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K6I41_RS15400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K6I41_RS15405	COG0489	protein tyrosine kinase activity
K6I41_RS15415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6I41_RS15415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6I41_RS15450	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K6I41_RS15455	COG2081	HI0933 family
K6I41_RS15465	COG0668	transmembrane transport
K6I41_RS15485	COG0583	DNA-binding transcription factor activity
K6I41_RS15505	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K6I41_RS15510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K6I41_RS15540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K6I41_RS15565	COG2199	diguanylate cyclase activity
K6I41_RS15580	COG0745	RESPONSE REGULATOR receiver
K6I41_RS15600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K6I41_RS15630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K6I41_RS15635	COG0583	DNA-binding transcription factor activity
K6I41_RS15665	COG1309	transcriptional regulator
K6I41_RS15670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K6I41_RS15695	COG0583	DNA-binding transcription factor activity
K6I41_RS15710	COG0583	DNA-binding transcription factor activity
K6I41_RS15715	COG1053	succinate dehydrogenase
K6I41_RS15730	COG1309	transcriptional regulator
K6I41_RS15740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K6I41_RS15745	COG2814	Major facilitator Superfamily
K6I41_RS15750	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS15755	COG0583	DNA-binding transcription factor activity
K6I41_RS15760	COG1063	alcohol dehydrogenase
K6I41_RS15790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K6I41_RS15795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K6I41_RS15800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K6I41_RS15820	COG2132	Multicopper oxidase
K6I41_RS15830	COG0561	phosphatase activity
K6I41_RS15835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K6I41_RS15860	COG1214	PFAM Peptidase M22, glycoprotease
K6I41_RS15920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K6I41_RS15925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K6I41_RS15930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K6I41_RS15990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K6I41_RS16000	COG1846	Transcriptional regulator
K6I41_RS16005	COG1764	response to oxidative stress
K6I41_RS16045	COG0037	tRNA processing
K6I41_RS16055	COG0248	Ppx GppA phosphatase
K6I41_RS16085	COG0072	phenylalanine-tRNA ligase activity
K6I41_RS16115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K6I41_RS16125	COG1238	metal cluster binding
K6I41_RS16130	COG0625	glutathione transferase activity
K6I41_RS16135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K6I41_RS16145	COG0318	PFAM AMP-dependent synthetase and ligase
K6I41_RS16150	COG3028	Belongs to the UPF0307 family
K6I41_RS16155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6I41_RS16175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K6I41_RS16180	COG0617	tRNA 3'-terminal CCA addition
K6I41_RS16185	COG1555	photosystem II stabilization
K6I41_RS16190	COG3956	TIGRFAM MazG family protein
K6I41_RS16195	COG4221	oxidoreductase activity
K6I41_RS16200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K6I41_RS16215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K6I41_RS16220	COG0784	Response regulator, receiver
K6I41_RS16220	COG2205	protein histidine kinase activity
K6I41_RS16220	COG5002	protein histidine kinase activity
K6I41_RS16225	COG1024	Enoyl-CoA hydratase
K6I41_RS16230	COG2084	Dehydrogenase
K6I41_RS16235	COG3622	Belongs to the hyi family
K6I41_RS16265	COG0697	spore germination
K6I41_RS16275	COG2814	Major facilitator Superfamily
K6I41_RS16280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K6I41_RS16295	COG0583	DNA-binding transcription factor activity
K6I41_RS16305	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K6I41_RS16315	COG0084	hydrolase, TatD family'
K6I41_RS16330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K6I41_RS16355	COG0440	acetolactate synthase activity
K6I41_RS16360	COG0028	Belongs to the TPP enzyme family
K6I41_RS16385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6I41_RS16390	COG1136	(ABC) transporter
K6I41_RS16390	COG0577	efflux transmembrane transporter activity
K6I41_RS16410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K6I41_RS16415	COG1162	GTPase activity
K6I41_RS16425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K6I41_RS16445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K6I41_RS16450	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS16500	COG1216	Glycosyl transferase, family 2
K6I41_RS16505	COG0318	PFAM AMP-dependent synthetase and ligase
K6I41_RS16515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K6I41_RS16540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6I41_RS16560	COG1426	Protein conserved in bacteria
K6I41_RS16580	COG2975	iron-sulfur cluster assembly
K6I41_RS16595	COG0793	Belongs to the peptidase S41A family
K6I41_RS16610	COG2267	carboxylic ester hydrolase activity
K6I41_RS16620	COG3265	gluconokinase activity
K6I41_RS16630	COG0800	Aldolase
K6I41_RS16645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K6I41_RS16650	COG0280	phosphate acetyltransferase
K6I41_RS16650	COG0857	belongs to the CobB CobQ family
K6I41_RS16655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K6I41_RS16655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
K6I41_RS16675	COG0740	serine-type endopeptidase activity
K6I41_RS16685	COG4774	siderophore transport
K6I41_RS16695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K6I41_RS16705	COG2813	Specifically methylates the guanine in position
K6I41_RS16705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K6I41_RS16805	COG0788	formyltetrahydrofolate deformylase activity
K6I41_RS16830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K6I41_RS16830	COG4651	solute:proton antiporter activity
K6I41_RS16850	COG0724	RNA recognition motif
K6I41_RS16855	COG0210	DNA helicase
K6I41_RS16880	COG1733	regulation of RNA biosynthetic process
K6I41_RS16885	COG0604	alcohol dehydrogenase
K6I41_RS16890	COG2900	Belongs to the SlyX family
K6I41_RS16895	COG0488	(ABC) transporter
K6I41_RS16905	COG1560	Kdo2-lipid A biosynthetic process
K6I41_RS16915	COG1301	dicarboxylic acid transport
K6I41_RS16970	COG0473	3-isopropylmalate dehydrogenase activity
K6I41_RS16995	COG0583	DNA-binding transcription factor activity
K6I41_RS17035	COG0583	DNA-binding transcription factor activity
K6I41_RS17045	COG0625	glutathione transferase activity
K6I41_RS17050	COG2378	regulation of single-species biofilm formation
K6I41_RS17065	COG1530	ribonuclease E activity
K6I41_RS17070	COG0318	PFAM AMP-dependent synthetase and ligase
K6I41_RS17085	COG0583	DNA-binding transcription factor activity
K6I41_RS17090	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS17095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K6I41_RS17105	COG0534	Mate efflux family protein
K6I41_RS17120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K6I41_RS17145	COG0493	'glutamate synthase
K6I41_RS17155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K6I41_RS17160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K6I41_RS17175	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K6I41_RS17185	COG0644	oxidoreductase
K6I41_RS17185	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
K6I41_RS17200	COG4535	Mg2 and Co2 transporter CorC
K6I41_RS17210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6I41_RS17235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K6I41_RS17245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K6I41_RS17255	COG0484	heat shock protein binding
K6I41_RS17260	COG0789	Transcriptional regulator
K6I41_RS17265	COG0598	Magnesium transport protein CorA
K6I41_RS17270	COG1185	polyribonucleotide nucleotidyltransferase activity
K6I41_RS17280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K6I41_RS17285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K6I41_RS17290	COG1074	ATP-dependent DNA helicase activity
K6I41_RS17295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K6I41_RS17315	COG2226	methyltransferase
K6I41_RS17325	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K6I41_RS17345	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K6I41_RS17360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K6I41_RS17360	COG2111	Na H antiporter
K6I41_RS17365	COG1006	Multisubunit Na H antiporter MnhC subunit
K6I41_RS17370	COG0651	ATP synthesis coupled electron transport
K6I41_RS17375	COG1863	multisubunit Na H antiporter MnhE subunit
K6I41_RS17380	COG2212	antiporter activity
K6I41_RS17385	COG1320	monovalent cation:proton antiporter activity
K6I41_RS17390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K6I41_RS17400	COG0195	Participates in both transcription termination and antitermination
K6I41_RS17450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K6I41_RS17455	COG0237	dephospho-CoA kinase activity
K6I41_RS17465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K6I41_RS17480	COG0497	DNA recombination
K6I41_RS17490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K6I41_RS17525	COG2169	Transcriptional regulator
K6I41_RS17525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K6I41_RS17535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K6I41_RS17605	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K6I41_RS17620	COG0326	Molecular chaperone. Has ATPase activity
K6I41_RS17635	COG2056	Na+-H+ antiporter family
K6I41_RS17670	COG0222	ribosome binding
K6I41_RS17675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K6I41_RS17735	COG0546	phosphoglycolate phosphatase activity
K6I41_RS17740	COG1716	ATPase activity
K6I41_RS17785	COG0181	hydroxymethylbilane synthase activity
K6I41_RS17795	COG3275	phosphorelay sensor kinase activity
K6I41_RS17815	COG1538	Outer membrane efflux protein
K6I41_RS17825	COG0697	spore germination
K6I41_RS17845	COG0494	nUDIX hydrolase
K6I41_RS17855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K6I41_RS17860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K6I41_RS17865	COG0772	Belongs to the SEDS family
K6I41_RS17890	COG4974	Belongs to the 'phage' integrase family
K6I41_RS17895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K6I41_RS17905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K6I41_RS17915	COG2197	response regulator
K6I41_RS17930	COG0793	Belongs to the peptidase S41A family
K6I41_RS17935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K6I41_RS17940	COG0795	lipopolysaccharide-transporting ATPase activity
K6I41_RS17980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K6I41_RS17980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K6I41_RS17990	COG0004	ammonium transporteR
K6I41_RS17995	COG0347	Belongs to the P(II) protein family
K6I41_RS18005	COG0606	chelatase, subunit chli
K6I41_RS18010	COG0431	NADPH-dependent FMN reductase
K6I41_RS18015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6I41_RS18020	COG0235	Class ii aldolase
K6I41_RS18025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6I41_RS18045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K6I41_RS18060	COG0318	PFAM AMP-dependent synthetase and ligase
K6I41_RS18070	COG0477	Major facilitator Superfamily
K6I41_RS18075	COG2860	membrane
K6I41_RS18085	COG1253	flavin adenine dinucleotide binding
K6I41_RS18095	COG2814	Major facilitator Superfamily
K6I41_RS18105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K6I41_RS18145	COG0655	NAD(P)H dehydrogenase (quinone) activity
K6I41_RS18160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K6I41_RS18195	COG1309	transcriptional regulator
K6I41_RS18230	COG0758	DNA mediated transformation
K6I41_RS18240	COG0697	spore germination
K6I41_RS18245	COG1309	transcriptional regulator
K6I41_RS18260	COG0386	Belongs to the glutathione peroxidase family
K6I41_RS18270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K6I41_RS18275	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K6I41_RS18325	COG1121	(ABC) transporter
K6I41_RS18330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K6I41_RS18335	COG1280	lysine exporter protein (LysE YggA)
K6I41_RS18340	COG2837	iron assimilation
K6I41_RS18345	COG0281	malic enzyme
K6I41_RS18390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K6I41_RS18390	COG0519	Catalyzes the synthesis of GMP from XMP
K6I41_RS18395	COG4399	Belongs to the UPF0754 family
K6I41_RS18400	COG2259	Doxx family
K6I41_RS18405	COG0586	Pfam SNARE associated Golgi protein
K6I41_RS18420	COG1192	Involved in chromosome partitioning
K6I41_RS18430	COG0271	Belongs to the BolA IbaG family
K6I41_RS18475	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS18485	COG2197	response regulator
K6I41_RS18495	COG3916	Acyl-homoserine-lactone synthase
K6I41_RS18500	COG0477	Major facilitator Superfamily
K6I41_RS18505	COG1024	Enoyl-CoA hydratase
K6I41_RS18510	COG1024	Enoyl-CoA hydratase
K6I41_RS18515	COG1960	acyl-CoA dehydrogenase activity
K6I41_RS18520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K6I41_RS18540	COG1113	amino acid transport
K6I41_RS18545	COG1113	amino acid transport
K6I41_RS18550	COG0251	oxidation-reduction process
K6I41_RS18590	COG0564	pseudouridine synthase activity
K6I41_RS18605	COG1309	transcriptional regulator
K6I41_RS18615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K6I41_RS18655	COG1051	belongs to the nudix hydrolase family
K6I41_RS18675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K6I41_RS18690	COG1802	Transcriptional regulator
K6I41_RS18695	COG1448	Aminotransferase
K6I41_RS18700	COG0277	FAD linked oxidase domain protein
K6I41_RS18710	COG2186	Transcriptional regulator
K6I41_RS18720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K6I41_RS18740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K6I41_RS18750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K6I41_RS18760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K6I41_RS18765	COG0438	transferase activity, transferring glycosyl groups
K6I41_RS18790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K6I41_RS18820	COG0728	peptidoglycan biosynthetic process
K6I41_RS18825	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6I41_RS18855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6I41_RS18855	COG1017	nitric oxide dioxygenase activity
K6I41_RS18880	COG0546	phosphoglycolate phosphatase activity
K6I41_RS18885	COG1028	Short-chain dehydrogenase reductase Sdr
K6I41_RS18900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K6I41_RS18900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K6I41_RS18905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6I41_RS18910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6I41_RS18915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6I41_RS18920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6I41_RS18925	COG1116	anion transmembrane transporter activity
K6I41_RS18930	COG1309	transcriptional regulator
K6I41_RS18935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K6I41_RS18945	COG0196	riboflavin kinase activity
K6I41_RS18950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K6I41_RS18960	COG1047	Peptidyl-prolyl cis-trans
K6I41_RS19005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K6I41_RS19010	COG0657	acetylesterase activity
K6I41_RS19030	COG0583	DNA-binding transcription factor activity
K6I41_RS19060	COG2951	lytic endotransglycosylase activity
K6I41_RS19065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K6I41_RS19080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K6I41_RS19090	COG0671	phosphoesterase, PA-phosphatase related
K6I41_RS19095	COG0861	Integral membrane protein TerC family
K6I41_RS19105	COG0402	S-adenosylhomocysteine deaminase activity
K6I41_RS19120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K6I41_RS19125	COG1230	cation diffusion facilitator family transporter
K6I41_RS19140	COG0706	membrane insertase activity