locus-tag	class	description
NDN12_RS00010	COG0592	DNA-directed DNA polymerase activity
NDN12_RS00020	COG0187	DNA topoisomerase II activity
NDN12_RS00035	COG0586	Pfam SNARE associated Golgi protein
NDN12_RS00040	COG0488	(ABC) transporter
NDN12_RS00070	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NDN12_RS00075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDN12_RS00130	COG1012	belongs to the aldehyde dehydrogenase family
NDN12_RS00135	COG0733	neurotransmitter:sodium symporter activity
NDN12_RS00175	COG0583	DNA-binding transcription factor activity
NDN12_RS00180	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS00185	COG2233	PERMEase
NDN12_RS00195	COG1309	transcriptional regulator
NDN12_RS00200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDN12_RS00230	COG2814	Major facilitator Superfamily
NDN12_RS00235	COG0656	L-ascorbic acid biosynthetic process
NDN12_RS00240	COG0583	DNA-binding transcription factor activity
NDN12_RS00250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDN12_RS00255	COG1064	alcohol dehydrogenase
NDN12_RS00260	COG2818	Glycosylase
NDN12_RS00275	COG1194	a g-specific adenine glycosylase
NDN12_RS00285	COG5487	UPF0391 membrane protein
NDN12_RS00290	COG2983	Belongs to the UPF0260 family
NDN12_RS00295	COG2133	pyrroloquinoline quinone binding
NDN12_RS00305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NDN12_RS00330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NDN12_RS00340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDN12_RS00345	COG1335	isochorismatase
NDN12_RS00350	COG1522	sequence-specific DNA binding
NDN12_RS00360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NDN12_RS00370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NDN12_RS00375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NDN12_RS00380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NDN12_RS00420	COG0753	catalase activity
NDN12_RS00480	COG0583	DNA-binding transcription factor activity
NDN12_RS00485	COG0583	DNA-binding transcription factor activity
NDN12_RS00520	COG0534	Mate efflux family protein
NDN12_RS00525	COG0436	Aminotransferase
NDN12_RS00530	COG2733	membrane
NDN12_RS00545	COG2918	glutathione biosynthetic process
NDN12_RS00560	COG1388	LysM domain
NDN12_RS00560	COG0791	NLP P60 protein
NDN12_RS00590	COG3150	esterase
NDN12_RS00645	COG0666	response to abiotic stimulus
NDN12_RS00645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NDN12_RS00665	COG3706	GGDEF domain
NDN12_RS00680	COG1393	Belongs to the ArsC family
NDN12_RS00685	COG0708	Exodeoxyribonuclease III
NDN12_RS00695	COG1181	Belongs to the D-alanine--D-alanine ligase family
NDN12_RS00705	COG0300	oxidoreductase activity
NDN12_RS00720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NDN12_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS00755	COG1846	Transcriptional regulator
NDN12_RS00760	COG0386	Belongs to the glutathione peroxidase family
NDN12_RS00765	COG0189	ligase activity
NDN12_RS00785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NDN12_RS00830	COG2119	membrane
NDN12_RS00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDN12_RS00835	COG0426	domain, Protein
NDN12_RS00855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NDN12_RS00880	COG1902	pentaerythritol trinitrate reductase activity
NDN12_RS00885	COG1519	Transferase
NDN12_RS00890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NDN12_RS00895	COG0668	transmembrane transport
NDN12_RS00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NDN12_RS00910	COG1335	isochorismatase
NDN12_RS00915	COG1522	sequence-specific DNA binding
NDN12_RS00945	COG3706	GGDEF domain
NDN12_RS00955	COG1309	transcriptional regulator
NDN12_RS00975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NDN12_RS00985	COG2814	Major facilitator Superfamily
NDN12_RS01010	COG1335	isochorismatase
NDN12_RS01020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NDN12_RS01050	COG3158	transport of potassium into the cell
NDN12_RS01065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NDN12_RS01080	COG0107	imidazoleglycerol-phosphate synthase activity
NDN12_RS01125	COG0659	secondary active sulfate transmembrane transporter activity
NDN12_RS01150	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NDN12_RS01185	COG2226	methyltransferase
NDN12_RS01190	COG0427	acetyl-CoA hydrolase
NDN12_RS01240	COG0583	DNA-binding transcription factor activity
NDN12_RS01245	COG2851	Citrate transporter
NDN12_RS01255	COG0477	Major facilitator Superfamily
NDN12_RS01260	COG0789	Transcriptional regulator
NDN12_RS01265	COG3320	Male sterility
NDN12_RS01265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDN12_RS01270	COG4221	oxidoreductase activity
NDN12_RS01280	COG0488	(ABC) transporter
NDN12_RS01340	COG0833	amino acid
NDN12_RS01365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NDN12_RS01375	COG3116	cell division
NDN12_RS01385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NDN12_RS01390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NDN12_RS01400	COG2226	methyltransferase
NDN12_RS01450	COG0067	glutamate synthase
NDN12_RS01450	COG0069	glutamate synthase activity
NDN12_RS01450	COG0070	glutamate synthase
NDN12_RS01455	COG0493	'glutamate synthase
NDN12_RS01470	COG1704	LemA family
NDN12_RS01475	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NDN12_RS01505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NDN12_RS01510	COG3307	-O-antigen
NDN12_RS01530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDN12_RS01540	COG0194	GDP metabolic process
NDN12_RS01545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NDN12_RS01615	COG0228	four-way junction DNA binding
NDN12_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NDN12_RS01630	COG0335	large ribosomal subunit rRNA binding
NDN12_RS01635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDN12_RS01655	COG5006	permease, DMT superfamily
NDN12_RS01660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NDN12_RS01665	COG0277	FAD linked oxidase domain protein
NDN12_RS01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NDN12_RS01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
NDN12_RS01710	COG1289	transmembrane transporter activity
NDN12_RS01720	COG0628	permease
NDN12_RS01725	COG1192	Involved in chromosome partitioning
NDN12_RS01735	COG2226	methyltransferase
NDN12_RS01770	COG1404	Belongs to the peptidase S8 family
NDN12_RS01815	COG0617	tRNA 3'-terminal CCA addition
NDN12_RS01815	COG0517	IMP dehydrogenase activity
NDN12_RS01815	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NDN12_RS01820	COG1983	PspC domain protein
NDN12_RS01830	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS01845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDN12_RS01855	COG0408	coproporphyrinogen oxidase activity
NDN12_RS01885	COG0513	Belongs to the DEAD box helicase family
NDN12_RS01890	COG1127	ABC transporter
NDN12_RS01895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NDN12_RS01900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NDN12_RS01905	COG2854	intermembrane phospholipid transfer
NDN12_RS01915	COG0598	Magnesium transport protein CorA
NDN12_RS01925	COG0494	nUDIX hydrolase
NDN12_RS01930	COG1040	competence protein
NDN12_RS01935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NDN12_RS01950	COG2937	Belongs to the GPAT DAPAT family
NDN12_RS01955	COG1946	Acyl-CoA thioesterase
NDN12_RS01960	COG1301	dicarboxylic acid transport
NDN12_RS01975	COG1959	2 iron, 2 sulfur cluster binding
NDN12_RS01985	COG0433	COG0433 Predicted ATPase
NDN12_RS02005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NDN12_RS02025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NDN12_RS02050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NDN12_RS02090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NDN12_RS02100	COG0200	Binds to the 23S rRNA
NDN12_RS02125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NDN12_RS02155	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS02160	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NDN12_RS02195	COG0697	spore germination
NDN12_RS02220	COG0339	signal peptide processing
NDN12_RS02230	COG0557	exoribonuclease II activity
NDN12_RS02275	COG0179	Fumarylacetoacetate (FAA) hydrolase
NDN12_RS02290	COG1295	ribonuclease BN
NDN12_RS02315	COG1785	Belongs to the alkaline phosphatase family
NDN12_RS02370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDN12_RS02370	COG2813	Specifically methylates the guanine in position
NDN12_RS02380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NDN12_RS02390	COG4774	siderophore transport
NDN12_RS02400	COG3128	pkhd-type hydroxylase
NDN12_RS02410	COG4771	TonB-dependent receptor
NDN12_RS02420	COG0740	serine-type endopeptidase activity
NDN12_RS02440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NDN12_RS02440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NDN12_RS02455	COG0857	belongs to the CobB CobQ family
NDN12_RS02455	COG0280	phosphate acetyltransferase
NDN12_RS02460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NDN12_RS02470	COG2267	carboxylic ester hydrolase activity
NDN12_RS02485	COG0793	Belongs to the peptidase S41A family
NDN12_RS02510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NDN12_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDN12_RS02530	COG1408	metallophosphoesterase
NDN12_RS02540	COG2199	diguanylate cyclase activity
NDN12_RS02595	COG1607	acyl-coa hydrolase
NDN12_RS02600	COG1956	GAF domain-containing protein
NDN12_RS02610	COG1666	GTP binding
NDN12_RS02640	COG0613	PHP domain protein
NDN12_RS02645	COG0583	DNA-binding transcription factor activity
NDN12_RS02650	COG0667	Aldo Keto reductase
NDN12_RS02655	COG3781	membrane
NDN12_RS02665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDN12_RS02705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NDN12_RS02715	COG1162	GTPase activity
NDN12_RS02720	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NDN12_RS02745	COG1538	Outer membrane efflux protein
NDN12_RS02750	COG1136	(ABC) transporter
NDN12_RS02750	COG0577	efflux transmembrane transporter activity
NDN12_RS02755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDN12_RS02760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NDN12_RS02785	COG0028	Belongs to the TPP enzyme family
NDN12_RS02790	COG0440	acetolactate synthase activity
NDN12_RS02815	COG1476	TRANSCRIPTIONal
NDN12_RS02835	COG1393	Belongs to the ArsC family
NDN12_RS02840	COG0640	Transcriptional regulator
NDN12_RS02845	COG0798	PFAM Bile acid sodium symporter
NDN12_RS02885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDN12_RS02900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NDN12_RS02910	COG0726	polysaccharide deacetylase
NDN12_RS02915	COG0084	hydrolase, TatD family'
NDN12_RS02930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NDN12_RS02950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDN12_RS02955	COG2197	response regulator
NDN12_RS02960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDN12_RS02960	COG2205	protein histidine kinase activity
NDN12_RS02970	COG2814	Major facilitator Superfamily
NDN12_RS03005	COG1051	belongs to the nudix hydrolase family
NDN12_RS03015	COG3622	Belongs to the hyi family
NDN12_RS03020	COG2084	Dehydrogenase
NDN12_RS03030	COG0784	Response regulator, receiver
NDN12_RS03030	COG5002	protein histidine kinase activity
NDN12_RS03030	COG2205	protein histidine kinase activity
NDN12_RS03050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDN12_RS03060	COG3956	TIGRFAM MazG family protein
NDN12_RS03065	COG1555	photosystem II stabilization
NDN12_RS03070	COG0617	tRNA 3'-terminal CCA addition
NDN12_RS03075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NDN12_RS03100	COG3028	Belongs to the UPF0307 family
NDN12_RS03110	COG0318	PFAM AMP-dependent synthetase and ligase
NDN12_RS03130	COG0625	glutathione transferase activity
NDN12_RS03145	COG1238	metal cluster binding
NDN12_RS03190	COG0072	phenylalanine-tRNA ligase activity
NDN12_RS03215	COG0248	Ppx GppA phosphatase
NDN12_RS03225	COG0037	tRNA processing
NDN12_RS03240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NDN12_RS03240	COG2755	lipolytic protein G-D-S-L family
NDN12_RS03245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDN12_RS03245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDN12_RS03270	COG1764	response to oxidative stress
NDN12_RS03275	COG1846	Transcriptional regulator
NDN12_RS03285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDN12_RS03345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDN12_RS03350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NDN12_RS03355	COG1595	DNA-templated transcription, initiation
NDN12_RS03365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NDN12_RS03415	COG0494	nUDIX hydrolase
NDN12_RS03425	COG1214	PFAM Peptidase M22, glycoprotease
NDN12_RS03430	COG1968	undecaprenyl-diphosphatase activity
NDN12_RS03460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NDN12_RS03470	COG2132	Multicopper oxidase
NDN12_RS03495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NDN12_RS03500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NDN12_RS03505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NDN12_RS03550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDN12_RS03555	COG1063	alcohol dehydrogenase
NDN12_RS03575	COG1309	transcriptional regulator
NDN12_RS03580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NDN12_RS03585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NDN12_RS03665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDN12_RS03680	COG0745	RESPONSE REGULATOR receiver
NDN12_RS03685	COG2205	protein histidine kinase activity
NDN12_RS03695	COG2199	diguanylate cyclase activity
NDN12_RS03700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDN12_RS03710	COG0649	NAD binding
NDN12_RS03710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDN12_RS03720	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NDN12_RS03735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDN12_RS03745	COG0713	ATP synthesis coupled electron transport
NDN12_RS03750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NDN12_RS03755	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NDN12_RS03780	COG0583	DNA-binding transcription factor activity
NDN12_RS03800	COG0668	transmembrane transport
NDN12_RS03810	COG2081	HI0933 family
NDN12_RS03820	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NDN12_RS03845	COG2226	methyltransferase
NDN12_RS03850	COG4716	Myosin-crossreactive antigen
NDN12_RS03860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDN12_RS03870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDN12_RS03870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDN12_RS03895	COG0489	protein tyrosine kinase activity
NDN12_RS03900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NDN12_RS03965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDN12_RS03980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NDN12_RS04000	COG0730	response to heat
NDN12_RS04020	COG1196	nuclear chromosome segregation
NDN12_RS04030	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NDN12_RS04050	COG2814	Major facilitator Superfamily
NDN12_RS04055	COG3135	benzoate transporter
NDN12_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS04065	COG0633	Ferredoxin
NDN12_RS04065	COG0543	2 iron, 2 sulfur cluster binding
NDN12_RS04070	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NDN12_RS04075	COG4638	Rieske (2fe-2S)
NDN12_RS04080	COG0583	DNA-binding transcription factor activity
NDN12_RS04085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NDN12_RS04095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDN12_RS04095	COG0596	Alpha beta hydrolase
NDN12_RS04095	COG2226	methyltransferase
NDN12_RS04100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NDN12_RS04100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NDN12_RS04110	COG4106	trans-aconitate 2-methyltransferase activity
NDN12_RS04145	COG4206	TonB-dependent receptor
NDN12_RS04150	COG4166	transmembrane transport
NDN12_RS04160	COG0339	signal peptide processing
NDN12_RS04185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NDN12_RS04190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NDN12_RS04205	COG0009	L-threonylcarbamoyladenylate synthase
NDN12_RS04210	COG3101	peptidyl-lysine hydroxylation
NDN12_RS04215	COG1399	metal-binding, possibly nucleic acid-binding protein
NDN12_RS04220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NDN12_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS04240	COG1652	LysM domain
NDN12_RS04245	COG0351	phosphomethylpyrimidine kinase
NDN12_RS04245	COG0352	thiamine-phosphate diphosphorylase activity
NDN12_RS04245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NDN12_RS04255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDN12_RS04290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDN12_RS04320	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NDN12_RS04335	COG0358	DNA primase activity
NDN12_RS04345	COG0564	pseudouridine synthase activity
NDN12_RS04350	COG1496	oxidoreductase activity
NDN12_RS04370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NDN12_RS04395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NDN12_RS04395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDN12_RS04420	COG1981	membrane
NDN12_RS04435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NDN12_RS04445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NDN12_RS04465	COG0456	acetyltransferase
NDN12_RS04475	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NDN12_RS04480	COG0500	methyltransferase
NDN12_RS04485	COG0492	ferredoxin-NADP+ reductase activity
NDN12_RS04490	COG1674	ftsk spoiiie
NDN12_RS04505	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NDN12_RS04510	COG2894	cell division
NDN12_RS04515	COG0850	regulation of cytokinetic process
NDN12_RS04525	COG0204	Acyl-transferase
NDN12_RS04530	COG2885	chlorophyll binding
NDN12_RS04535	COG0210	DNA helicase
NDN12_RS04540	COG0756	dUTP diphosphatase activity
NDN12_RS04560	COG0121	glutamine amidotransferase
NDN12_RS04580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDN12_RS04585	COG0735	belongs to the Fur family
NDN12_RS04610	COG0546	phosphoglycolate phosphatase activity
NDN12_RS04625	COG0420	3'-5' exonuclease activity
NDN12_RS04630	COG1024	Enoyl-CoA hydratase
NDN12_RS04650	COG1090	epimerase
NDN12_RS04655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDN12_RS04665	COG2050	protein possibly involved in aromatic compounds catabolism
NDN12_RS04670	COG2226	methyltransferase
NDN12_RS04675	COG4638	Rieske (2fe-2S)
NDN12_RS04680	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NDN12_RS04685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NDN12_RS04685	COG0543	2 iron, 2 sulfur cluster binding
NDN12_RS04700	COG1566	PFAM secretion protein HlyD family protein
NDN12_RS04705	COG2814	Major facilitator Superfamily
NDN12_RS04715	COG0582	viral genome integration into host DNA
NDN12_RS04775	COG1401	restriction endodeoxyribonuclease activity
NDN12_RS04775	COG1401	restriction endodeoxyribonuclease activity
NDN12_RS04810	COG1231	oxidoreductase activity
NDN12_RS04865	COG4221	oxidoreductase activity
NDN12_RS04875	COG1309	transcriptional regulator
NDN12_RS04885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDN12_RS04925	COG2072	flavoprotein involved in K transport
NDN12_RS04950	COG3121	Chaperone
NDN12_RS04955	COG3188	usher protein
NDN12_RS04965	COG3121	Chaperone
NDN12_RS05020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDN12_RS05025	COG0235	Class ii aldolase
NDN12_RS05030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDN12_RS05040	COG4221	oxidoreductase activity
NDN12_RS05045	COG4689	acetoacetate decarboxylase
NDN12_RS05050	COG1902	pentaerythritol trinitrate reductase activity
NDN12_RS05050	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDN12_RS05065	COG0300	oxidoreductase activity
NDN12_RS05070	COG2072	flavoprotein involved in K transport
NDN12_RS05085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDN12_RS05090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDN12_RS05100	COG0789	Transcriptional regulator
NDN12_RS05115	COG2375	cellular response to nickel ion
NDN12_RS05115	COG1132	(ABC) transporter
NDN12_RS05120	COG1132	(ABC) transporter
NDN12_RS05125	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDN12_RS05130	COG4605	iron ion homeostasis
NDN12_RS05135	COG4604	ABC transporter, ATP-binding protein
NDN12_RS05140	COG4607	ABC-type enterochelin transport system periplasmic component
NDN12_RS05145	COG4774	siderophore transport
NDN12_RS05205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDN12_RS05230	COG2814	Major facilitator Superfamily
NDN12_RS05245	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDN12_RS05255	COG0154	amidase activity
NDN12_RS05270	COG4638	Rieske (2fe-2S)
NDN12_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS05290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDN12_RS05300	COG3733	amine oxidase
NDN12_RS05315	COG1012	belongs to the aldehyde dehydrogenase family
NDN12_RS05320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDN12_RS05325	COG0183	Belongs to the thiolase family
NDN12_RS05330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDN12_RS05335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDN12_RS05345	COG4829	muconolactone delta-isomerase
NDN12_RS05350	COG4948	Mandelate Racemase Muconate Lactonizing
NDN12_RS05355	COG0583	DNA-binding transcription factor activity
NDN12_RS05370	COG4771	TonB-dependent receptor
NDN12_RS05400	COG1595	DNA-templated transcription, initiation
NDN12_RS05425	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS05450	COG4774	siderophore transport
NDN12_RS05465	COG0281	malic enzyme
NDN12_RS05475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NDN12_RS05480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDN12_RS05485	COG3138	arginine N-succinyltransferase
NDN12_RS05490	COG1012	belongs to the aldehyde dehydrogenase family
NDN12_RS05505	COG0833	amino acid
NDN12_RS05515	COG2995	paraquat-inducible protein a
NDN12_RS05520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NDN12_RS05520	COG3008	intermembrane lipid transfer
NDN12_RS05530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDN12_RS05535	COG0671	phosphoesterase, PA-phosphatase related
NDN12_RS05620	COG2885	chlorophyll binding
NDN12_RS05630	COG0725	ABC transporter, periplasmic molybdate-binding protein
NDN12_RS05635	COG4149	molybdate abc transporter
NDN12_RS05650	COG1230	cation diffusion facilitator family transporter
NDN12_RS05665	COG1280	lysine exporter protein (LysE YggA)
NDN12_RS05670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDN12_RS05675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDN12_RS05680	COG1045	serine acetyltransferase
NDN12_RS05690	COG4521	taurine ABC transporter
NDN12_RS05695	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NDN12_RS05700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDN12_RS05705	COG2175	clavaminate synthase activity
NDN12_RS05740	COG0589	response to stress
NDN12_RS05760	COG0242	peptide deformylase activity
NDN12_RS05765	COG2066	Belongs to the glutaminase family
NDN12_RS05790	COG0306	phosphate transporter
NDN12_RS05805	COG1115	amino acid carrier protein
NDN12_RS05810	COG1113	amino acid transport
NDN12_RS05820	COG0019	diaminopimelate decarboxylase activity
NDN12_RS05825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NDN12_RS05830	COG1280	lysine exporter protein (LysE YggA)
NDN12_RS05835	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NDN12_RS05895	COG1671	Belongs to the UPF0178 family
NDN12_RS05910	COG4591	ABC-type transport system involved in lipoprotein release permease component
NDN12_RS05915	COG1136	(ABC) transporter
NDN12_RS05920	COG2333	competence protein COMEC
NDN12_RS05920	COG0658	competence protein
NDN12_RS05930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NDN12_RS05930	COG0616	signal peptide processing
NDN12_RS05940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NDN12_RS05950	COG0628	permease
NDN12_RS05955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NDN12_RS05985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDN12_RS06000	COG2885	chlorophyll binding
NDN12_RS06005	COG0823	Involved in the tonB-independent uptake of proteins
NDN12_RS06025	COG0824	Thioesterase
NDN12_RS06055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDN12_RS06055	COG0047	phosphoribosylformylglycinamidine synthase activity
NDN12_RS06060	COG2814	Major facilitator Superfamily
NDN12_RS06080	COG1929	Belongs to the glycerate kinase type-1 family
NDN12_RS06085	COG1024	Enoyl-CoA hydratase
NDN12_RS06090	COG1051	belongs to the nudix hydrolase family
NDN12_RS06090	COG1056	cytidyltransferase-related domain
NDN12_RS06105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NDN12_RS06120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NDN12_RS06125	COG0602	queuosine metabolic process
NDN12_RS06140	COG0583	DNA-binding transcription factor activity
NDN12_RS06145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NDN12_RS06150	COG4208	sulfate ABC transporter
NDN12_RS06155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NDN12_RS06165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NDN12_RS06170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDN12_RS06175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NDN12_RS06195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDN12_RS06205	COG0481	GTPase activity
NDN12_RS06220	COG0571	ribonuclease III activity
NDN12_RS06225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NDN12_RS06240	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NDN12_RS06275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NDN12_RS06280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NDN12_RS06285	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NDN12_RS06295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDN12_RS06310	COG2011	ABC-type metal ion transport system permease component
NDN12_RS06315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDN12_RS06320	COG1464	Belongs to the NlpA lipoprotein family
NDN12_RS06330	COG0138	bifunctional purine biosynthesis protein purh
NDN12_RS06335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NDN12_RS06380	COG1477	protein flavinylation
NDN12_RS06390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDN12_RS06415	COG2252	PERMEase
NDN12_RS06420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NDN12_RS06425	COG3038	cytochrome b561
NDN12_RS06435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDN12_RS06450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDN12_RS06455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NDN12_RS06465	COG0456	acetyltransferase
NDN12_RS06475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NDN12_RS06490	COG2308	Evidence 4 Homologs of previously reported genes of
NDN12_RS06500	COG1305	Transglutaminase-like
NDN12_RS06515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDN12_RS06520	COG0305	Participates in initiation and elongation during chromosome replication
NDN12_RS06525	COG1733	regulation of RNA biosynthetic process
NDN12_RS06530	COG2249	NAD(P)H dehydrogenase (quinone) activity
NDN12_RS06560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NDN12_RS06565	COG1845	cytochrome c oxidase, subunit III
NDN12_RS06570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NDN12_RS06575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NDN12_RS06595	COG5001	Diguanylate cyclase
NDN12_RS06595	COG3300	MHYT domain
NDN12_RS06600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDN12_RS06635	COG0802	atpase or kinase
NDN12_RS06640	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDN12_RS06650	COG1923	regulation of RNA biosynthetic process
NDN12_RS06655	COG0697	spore germination
NDN12_RS06665	COG2249	NAD(P)H dehydrogenase (quinone) activity
NDN12_RS06670	COG0778	Nitroreductase
NDN12_RS06675	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDN12_RS06685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDN12_RS06690	COG0505	Belongs to the CarA family
NDN12_RS06700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NDN12_RS06720	COG0583	DNA-binding transcription factor activity
NDN12_RS06725	COG0473	3-isopropylmalate dehydrogenase activity
NDN12_RS06735	COG0657	acetylesterase activity
NDN12_RS06740	COG4638	Rieske (2fe-2S)
NDN12_RS06745	COG1012	belongs to the aldehyde dehydrogenase family
NDN12_RS06760	COG2985	domain, Protein
NDN12_RS06775	COG1414	Transcriptional regulator
NDN12_RS06780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDN12_RS06785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDN12_RS06790	COG0183	Belongs to the thiolase family
NDN12_RS06795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NDN12_RS06800	COG0596	Alpha beta hydrolase
NDN12_RS06805	COG2271	Major facilitator Superfamily
NDN12_RS06810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NDN12_RS06815	COG3485	protocatechuate 3,4-dioxygenase
NDN12_RS06820	COG3485	protocatechuate 3,4-dioxygenase
NDN12_RS06825	COG0710	3-dehydroquinate dehydratase activity
NDN12_RS06830	COG3420	alginic acid biosynthetic process
NDN12_RS06835	COG3659	wide pore channel activity
NDN12_RS06840	COG4993	Dehydrogenase
NDN12_RS06850	COG2351	hydroxyisourate hydrolase activity
NDN12_RS06855	COG2233	PERMEase
NDN12_RS06865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDN12_RS06870	COG2186	Transcriptional regulator
NDN12_RS06890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDN12_RS06900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDN12_RS06920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NDN12_RS06930	COG0583	DNA-binding transcription factor activity
NDN12_RS06940	COG2188	Transcriptional regulator
NDN12_RS06970	COG0010	Belongs to the arginase family
NDN12_RS06975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NDN12_RS07000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDN12_RS07005	COG1294	oxidase, subunit
NDN12_RS07010	COG1271	oxidase subunit
NDN12_RS07025	COG0243	molybdopterin cofactor binding
NDN12_RS07030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NDN12_RS07035	COG2837	iron assimilation
NDN12_RS07045	COG1538	Outer membrane efflux protein
NDN12_RS07050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDN12_RS07055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDN12_RS07060	COG0745	RESPONSE REGULATOR receiver
NDN12_RS07070	COG5002	protein histidine kinase activity
NDN12_RS07075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDN12_RS07080	COG0667	Aldo Keto reductase
NDN12_RS07090	COG2358	TRAP transporter, solute receptor (TAXI family
NDN12_RS07100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDN12_RS07115	COG1116	anion transmembrane transporter activity
NDN12_RS07120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDN12_RS07130	COG3829	transcription factor binding
NDN12_RS07135	COG3585	molybdate ion transport
NDN12_RS07150	COG1309	transcriptional regulator
NDN12_RS07170	COG2072	flavoprotein involved in K transport
NDN12_RS07175	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NDN12_RS07180	COG0501	Belongs to the peptidase M48B family
NDN12_RS07190	COG1765	OsmC-like protein
NDN12_RS07285	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NDN12_RS07305	COG3634	alkyl hydroperoxide reductase activity
NDN12_RS07325	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDN12_RS07340	COG1643	Atp-dependent helicase
NDN12_RS07355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NDN12_RS07360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDN12_RS07380	COG2951	lytic endotransglycosylase activity
NDN12_RS07385	COG0772	Belongs to the SEDS family
NDN12_RS07400	COG0842	Transport permease protein
NDN12_RS07405	COG1131	(ABC) transporter
NDN12_RS07450	COG0439	Biotin carboxylase
NDN12_RS07455	COG0864	Transcriptional regulator
NDN12_RS07460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDN12_RS07475	COG1116	anion transmembrane transporter activity
NDN12_RS07485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NDN12_RS07490	COG0826	peptidase U32
NDN12_RS07500	COG4682	membrane
NDN12_RS07535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDN12_RS07545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NDN12_RS07570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NDN12_RS07600	COG0729	surface antigen
NDN12_RS07635	COG0471	metal ion transport
NDN12_RS07640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDN12_RS07645	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDN12_RS07650	COG4605	iron ion homeostasis
NDN12_RS07655	COG4604	ABC transporter, ATP-binding protein
NDN12_RS07660	COG4607	ABC-type enterochelin transport system periplasmic component
NDN12_RS07665	COG3647	Membrane
NDN12_RS07670	COG2814	Major facilitator Superfamily
NDN12_RS07680	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDN12_RS07685	COG0583	DNA-binding transcription factor activity
NDN12_RS07710	COG1720	tRNA m6t6A37 methyltransferase activity
NDN12_RS07715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NDN12_RS07740	COG0494	nUDIX hydrolase
NDN12_RS07750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NDN12_RS07755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDN12_RS07760	COG3139	Protein of unknown function (DUF1315)
NDN12_RS07785	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS07805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NDN12_RS07815	COG2195	Cleaves the N-terminal amino acid of tripeptides
NDN12_RS07835	COG1690	Belongs to the RtcB family
NDN12_RS07840	COG1234	tRNA 3'-trailer cleavage
NDN12_RS07845	COG4650	regulator
NDN12_RS07890	COG2363	Small membrane protein
NDN12_RS07910	COG0513	Belongs to the DEAD box helicase family
NDN12_RS07920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NDN12_RS07930	COG3178	'Phosphotransferase
NDN12_RS07935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NDN12_RS07945	COG1192	Involved in chromosome partitioning
NDN12_RS07950	COG1475	DNA binding
NDN12_RS07955	COG0811	peptide transport
NDN12_RS07965	COG1132	(ABC) transporter
NDN12_RS07970	COG1663	tetraacyldisaccharide 4'-kinase activity
NDN12_RS08000	COG0084	hydrolase, TatD family'
NDN12_RS08065	COG0776	regulation of translation
NDN12_RS08095	COG2431	L-lysine efflux transmembrane transporter activity
NDN12_RS08100	COG1309	transcriptional regulator
NDN12_RS08105	COG2814	Major facilitator Superfamily
NDN12_RS08120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NDN12_RS08125	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NDN12_RS08165	COG0024	Methionine aminopeptidase
NDN12_RS08170	COG0583	DNA-binding transcription factor activity
NDN12_RS08175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDN12_RS08185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NDN12_RS08190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDN12_RS08195	COG0517	IMP dehydrogenase activity
NDN12_RS08220	COG0552	protein localization to endoplasmic reticulum
NDN12_RS08265	COG4890	Cyd operon protein YbgT
NDN12_RS08270	COG1294	oxidase, subunit
NDN12_RS08295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDN12_RS08320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NDN12_RS08325	COG0569	domain protein
NDN12_RS08330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDN12_RS08350	COG1785	Belongs to the alkaline phosphatase family
NDN12_RS08370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NDN12_RS08375	COG0542	response to heat
NDN12_RS08385	COG0488	(ABC) transporter
NDN12_RS08390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NDN12_RS08395	COG2267	carboxylic ester hydrolase activity
NDN12_RS08405	COG1902	pentaerythritol trinitrate reductase activity
NDN12_RS08405	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDN12_RS08440	COG0148	phosphopyruvate hydratase activity
NDN12_RS08445	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NDN12_RS08495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDN12_RS08515	COG1280	lysine exporter protein (LysE YggA)
NDN12_RS08545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDN12_RS08555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NDN12_RS08575	COG1802	Transcriptional regulator
NDN12_RS08585	COG2207	Transcriptional regulator
NDN12_RS08590	COG1063	alcohol dehydrogenase
NDN12_RS08605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDN12_RS08655	COG0697	spore germination
NDN12_RS08660	COG0583	DNA-binding transcription factor activity
NDN12_RS08665	COG1944	ATP diphosphatase activity
NDN12_RS08675	COG0633	Ferredoxin
NDN12_RS08690	COG2217	Heavy metal translocating P-type atpase
NDN12_RS08725	COG2205	protein histidine kinase activity
NDN12_RS08730	COG0745	RESPONSE REGULATOR receiver
NDN12_RS08745	COG3220	belongs to the UPF0276 family
NDN12_RS08755	COG1595	DNA-templated transcription, initiation
NDN12_RS08780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDN12_RS08795	COG0642	Histidine kinase
NDN12_RS08800	COG0745	RESPONSE REGULATOR receiver
NDN12_RS08830	COG3268	Saccharopine dehydrogenase
NDN12_RS08845	COG1902	pentaerythritol trinitrate reductase activity
NDN12_RS08845	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDN12_RS08860	COG0789	Transcriptional regulator
NDN12_RS08870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NDN12_RS08875	COG0583	DNA-binding transcription factor activity
NDN12_RS08880	COG1595	DNA-templated transcription, initiation
NDN12_RS08890	COG4771	TonB-dependent receptor
NDN12_RS08930	COG2814	Major facilitator Superfamily
NDN12_RS08950	COG1294	oxidase, subunit
NDN12_RS08955	COG1271	oxidase subunit
NDN12_RS09000	COG0625	glutathione transferase activity
NDN12_RS09005	COG0583	DNA-binding transcription factor activity
NDN12_RS09015	COG1346	cytolysis
NDN12_RS09065	COG1309	transcriptional regulator
NDN12_RS09070	COG1595	DNA-templated transcription, initiation
NDN12_RS09110	COG0601	transmembrane transport
NDN12_RS09115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDN12_RS09135	COG1132	(ABC) transporter
NDN12_RS09140	COG1132	(ABC) transporter
NDN12_RS09160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDN12_RS09165	COG3829	transcription factor binding
NDN12_RS09175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDN12_RS09190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDN12_RS09195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDN12_RS09205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDN12_RS09240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDN12_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS09265	COG4628	conserved protein (DUF2132)
NDN12_RS09285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NDN12_RS09290	COG1074	ATP-dependent DNA helicase activity
NDN12_RS09400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDN12_RS09405	COG2267	carboxylic ester hydrolase activity
NDN12_RS09410	COG0671	phosphoesterase, PA-phosphatase related
NDN12_RS09410	COG2453	phosphatase
NDN12_RS09425	COG4589	Belongs to the CDS family
NDN12_RS09430	COG2207	Transcriptional regulator
NDN12_RS09435	COG2249	NAD(P)H dehydrogenase (quinone) activity
NDN12_RS09445	COG3712	iron ion homeostasis
NDN12_RS09450	COG1595	DNA-templated transcription, initiation
NDN12_RS09470	COG3706	GGDEF domain
NDN12_RS09485	COG0133	tryptophan synthase activity
NDN12_RS09495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDN12_RS09515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NDN12_RS09570	COG3772	lysozyme
NDN12_RS09585	COG0537	adenosine 5'-monophosphoramidase activity
NDN12_RS09610	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDN12_RS09640	COG0730	response to heat
NDN12_RS09650	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NDN12_RS09665	COG4771	TonB-dependent receptor
NDN12_RS09690	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NDN12_RS09705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NDN12_RS09720	COG2223	nitrite transmembrane transporter activity
NDN12_RS09765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDN12_RS09770	COG1414	Transcriptional regulator
NDN12_RS09785	COG3327	negative regulation of DNA-templated transcription, initiation
NDN12_RS09790	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NDN12_RS09795	COG0183	Belongs to the thiolase family
NDN12_RS09800	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDN12_RS09805	COG1024	Enoyl-CoA hydratase
NDN12_RS09810	COG1024	Enoyl-CoA hydratase
NDN12_RS09815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NDN12_RS09820	COG2151	metal-sulfur cluster biosynthetic enzyme
NDN12_RS09825	COG3396	Phenylacetate-CoA oxygenase
NDN12_RS09830	COG3460	Phenylacetate-CoA oxygenase
NDN12_RS09835	COG3396	Phenylacetate-CoA oxygenase
NDN12_RS09840	COG1012	belongs to the aldehyde dehydrogenase family
NDN12_RS09840	COG2030	dehydratase
NDN12_RS09850	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS09855	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS09860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDN12_RS09865	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDN12_RS09870	COG2207	Transcriptional regulator
NDN12_RS09875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDN12_RS09885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NDN12_RS09910	COG0575	Belongs to the CDS family
NDN12_RS09915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NDN12_RS09935	COG3852	Histidine kinase
NDN12_RS09940	COG2204	response regulator
NDN12_RS09995	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NDN12_RS10010	COG2920	part of a sulfur-relay system
NDN12_RS10015	COG0697	spore germination
NDN12_RS10020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDN12_RS10030	COG0303	'Molybdopterin
NDN12_RS10035	COG0315	cyclic pyranopterin monophosphate synthase activity
NDN12_RS10035	COG0521	Mo-molybdopterin cofactor biosynthetic process
NDN12_RS10055	COG0243	molybdopterin cofactor binding
NDN12_RS10070	COG0583	DNA-binding transcription factor activity
NDN12_RS10075	COG0477	Major facilitator Superfamily
NDN12_RS10085	COG0243	molybdopterin cofactor binding
NDN12_RS10090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDN12_RS10095	COG2146	nitrite reductase [NAD(P)H] activity
NDN12_RS10095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDN12_RS10100	COG2223	nitrite transmembrane transporter activity
NDN12_RS10110	COG1116	anion transmembrane transporter activity
NDN12_RS10110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDN12_RS10125	COG0439	Biotin carboxylase
NDN12_RS10140	COG2814	Major facilitator Superfamily
NDN12_RS10145	COG1113	amino acid transport
NDN12_RS10155	COG0625	glutathione transferase activity
NDN12_RS10180	COG0069	glutamate synthase activity
NDN12_RS10215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDN12_RS10255	COG1454	alcohol dehydrogenase
NDN12_RS10260	COG0824	Thioesterase
NDN12_RS10265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NDN12_RS10270	COG2850	peptidyl-arginine hydroxylation
NDN12_RS10310	COG3122	Protein conserved in bacteria
NDN12_RS10315	COG0668	transmembrane transport
NDN12_RS10365	COG0786	glutamate:sodium symporter activity
NDN12_RS10385	COG1132	(ABC) transporter
NDN12_RS10390	COG2030	dehydratase
NDN12_RS10405	COG3397	chitin binding
NDN12_RS10410	COG1027	Aspartate ammonia-lyase
NDN12_RS10415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDN12_RS10425	COG0506	proline dehydrogenase activity
NDN12_RS10425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NDN12_RS10425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NDN12_RS10430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NDN12_RS10435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NDN12_RS10445	COG3698	Phosphodiester glycosidase
NDN12_RS10490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NDN12_RS10495	COG2353	YceI-like domain
NDN12_RS10515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NDN12_RS10520	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NDN12_RS10540	COG3042	response to heat
NDN12_RS10550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDN12_RS10555	COG1278	Cold shock
NDN12_RS10560	COG1278	Cold shock
NDN12_RS10580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NDN12_RS10580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NDN12_RS10605	COG3539	Fimbrial protein
NDN12_RS10620	COG3539	Fimbrial protein
NDN12_RS10645	COG0753	catalase activity
NDN12_RS10730	COG1335	isochorismatase
NDN12_RS10785	COG1464	Belongs to the NlpA lipoprotein family
NDN12_RS10790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDN12_RS10795	COG2011	ABC-type metal ion transport system permease component
NDN12_RS10800	COG0012	GTP binding
NDN12_RS10820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDN12_RS10835	COG1942	4-Oxalocrotonate Tautomerase
NDN12_RS10880	COG1280	lysine exporter protein (LysE YggA)
NDN12_RS10890	COG0386	Belongs to the glutathione peroxidase family
NDN12_RS10900	COG0436	Aminotransferase
NDN12_RS10935	COG3634	alkyl hydroperoxide reductase activity
NDN12_RS10990	COG1286	toxin biosynthetic process
NDN12_RS11020	COG0778	Nitroreductase
NDN12_RS11045	COG0424	maF-like protein
NDN12_RS11070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NDN12_RS11080	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS11085	COG0183	Belongs to the thiolase family
NDN12_RS11100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NDN12_RS11105	COG0702	epimerase
NDN12_RS11110	COG0268	Binds directly to 16S ribosomal RNA
NDN12_RS11130	COG1218	3'(2'),5'-bisphosphate nucleotidase
NDN12_RS11135	COG1011	Hydrolase
NDN12_RS11140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NDN12_RS11150	COG2137	regulation of response to DNA damage stimulus
NDN12_RS11165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NDN12_RS11170	COG0776	regulation of translation
NDN12_RS11195	COG0822	iron-sulfur transferase activity
NDN12_RS11200	COG0316	Belongs to the HesB IscA family
NDN12_RS11235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NDN12_RS11255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NDN12_RS11265	COG3135	benzoate transporter
NDN12_RS11270	COG0475	glutathione-regulated potassium exporter activity
NDN12_RS11270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDN12_RS11295	COG0308	aminopeptidase N
NDN12_RS11330	COG2807	transmembrane transport
NDN12_RS11335	COG0590	tRNA wobble adenosine to inosine editing
NDN12_RS11355	COG0028	Belongs to the TPP enzyme family
NDN12_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS11385	COG2271	Major facilitator Superfamily
NDN12_RS11390	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDN12_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS11420	COG1414	Transcriptional regulator
NDN12_RS11425	COG4221	oxidoreductase activity
NDN12_RS11440	COG1522	sequence-specific DNA binding
NDN12_RS11445	COG5006	permease, DMT superfamily
NDN12_RS11450	COG2814	Major facilitator Superfamily
NDN12_RS11470	COG0318	PFAM AMP-dependent synthetase and ligase
NDN12_RS11475	COG1309	transcriptional regulator
NDN12_RS11480	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS11485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NDN12_RS11490	COG1024	Enoyl-CoA hydratase
NDN12_RS11495	COG4770	biotin carboxylase activity
NDN12_RS11505	COG0583	DNA-binding transcription factor activity
NDN12_RS11515	COG3214	Protein conserved in bacteria
NDN12_RS11525	COG2223	nitrite transmembrane transporter activity
NDN12_RS11550	COG2814	Major facilitator Superfamily
NDN12_RS11575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDN12_RS11590	COG0765	amino acid transport
NDN12_RS11615	COG1113	amino acid transport
NDN12_RS11620	COG1570	exodeoxyribonuclease VII activity
NDN12_RS11635	COG2194	sulfuric ester hydrolase activity
NDN12_RS11655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NDN12_RS11670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NDN12_RS11685	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NDN12_RS11700	COG1157	protein secretion by the type III secretion system
NDN12_RS11715	COG1766	The M ring may be actively involved in energy transduction
NDN12_RS11720	COG1677	Flagellar hook-basal body complex protein FliE
NDN12_RS11725	COG1558	bacterial-type flagellum-dependent cell motility
NDN12_RS11730	COG1815	bacterial-type flagellum-dependent cell motility
NDN12_RS11735	COG1706	bacterial-type flagellum-dependent cell motility
NDN12_RS11740	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NDN12_RS11750	COG4786	Flagellar basal body rod
NDN12_RS11760	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDN12_RS11765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDN12_RS11770	COG1684	flagellar biosynthetic protein fliR
NDN12_RS11775	COG1987	bacterial-type flagellum assembly
NDN12_RS11805	COG1902	pentaerythritol trinitrate reductase activity
NDN12_RS11805	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDN12_RS11810	COG0697	spore germination
NDN12_RS11815	COG0583	DNA-binding transcription factor activity
NDN12_RS11830	COG1741	Belongs to the pirin family
NDN12_RS11870	COG0714	Associated with various cellular activities
NDN12_RS11875	COG2879	small protein
NDN12_RS11880	COG1966	Carbon starvation protein
NDN12_RS11885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NDN12_RS11925	COG1067	ATP-dependent peptidase activity
NDN12_RS11930	COG0583	DNA-binding transcription factor activity
NDN12_RS11960	COG1686	Belongs to the peptidase S11 family
NDN12_RS11965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NDN12_RS11980	COG0482	sulfurtransferase activity
NDN12_RS12020	COG1113	amino acid transport
NDN12_RS12050	COG0515	serine threonine protein kinase
NDN12_RS12050	COG2815	serine threonine protein kinase
NDN12_RS12085	COG0697	spore germination
NDN12_RS12120	COG1610	YqeY-like protein
NDN12_RS12135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDN12_RS12140	COG4783	chaperone-mediated protein folding
NDN12_RS12165	COG0702	epimerase
NDN12_RS12175	COG0583	DNA-binding transcription factor activity
NDN12_RS12180	COG0300	oxidoreductase activity
NDN12_RS12185	COG4221	oxidoreductase activity
NDN12_RS12190	COG1073	alpha beta
NDN12_RS12195	COG1073	alpha beta
NDN12_RS12200	COG2207	Transcriptional regulator
NDN12_RS12205	COG1902	pentaerythritol trinitrate reductase activity
NDN12_RS12210	COG2207	Transcriptional regulator
NDN12_RS12250	COG1629	transport
NDN12_RS12260	COG4770	biotin carboxylase activity
NDN12_RS12280	COG1914	H( )-stimulated, divalent metal cation uptake system
NDN12_RS12285	COG0583	DNA-binding transcription factor activity
NDN12_RS12295	COG1253	flavin adenine dinucleotide binding
NDN12_RS12310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NDN12_RS12320	COG4122	O-methyltransferase activity
NDN12_RS12330	COG0110	maltose O-acetyltransferase activity
NDN12_RS12345	COG2274	protein secretion by the type I secretion system
NDN12_RS12350	COG1538	Outer membrane efflux protein
NDN12_RS12355	COG1137	ATPase activity
NDN12_RS12360	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NDN12_RS12370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NDN12_RS12375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NDN12_RS12375	COG0517	IMP dehydrogenase activity
NDN12_RS12395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NDN12_RS12400	COG3015	lipoprotein NlpE involved in copper resistance
NDN12_RS12410	COG0052	Belongs to the universal ribosomal protein uS2 family
NDN12_RS12415	COG0024	Methionine aminopeptidase
NDN12_RS12425	COG2223	nitrite transmembrane transporter activity
NDN12_RS12445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDN12_RS12450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NDN12_RS12455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDN12_RS12460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDN12_RS12475	COG1253	flavin adenine dinucleotide binding
NDN12_RS12480	COG0222	ribosome binding
NDN12_RS12520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NDN12_RS12530	COG1773	rubredoxin
NDN12_RS12535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDN12_RS12545	COG0583	DNA-binding transcription factor activity
NDN12_RS12605	COG0556	nucleotide-excision repair
NDN12_RS12620	COG0436	Aminotransferase
NDN12_RS12665	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NDN12_RS12670	COG3161	chorismate lyase activity
NDN12_RS12675	COG0174	glutamine synthetase
NDN12_RS12680	COG0512	Glutamine amidotransferase of anthranilate synthase
NDN12_RS12685	COG1823	symporter activity
NDN12_RS12720	COG0302	gtp cyclohydrolase
NDN12_RS12740	COG3739	integral membrane protein
NDN12_RS12755	COG5001	Diguanylate cyclase
NDN12_RS12755	COG2203	Gaf domain
NDN12_RS12755	COG4251	negative regulation of phosphorylation
NDN12_RS12755	COG3706	GGDEF domain
NDN12_RS12765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NDN12_RS12780	COG4172	Belongs to the ABC transporter superfamily
NDN12_RS12785	COG4239	(ABC) transporter, permease
NDN12_RS12790	COG4174	ABC transporter (Permease)
NDN12_RS12800	COG1388	LysM domain
NDN12_RS12800	COG0741	lytic transglycosylase activity
NDN12_RS12870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDN12_RS12875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDN12_RS12885	COG0006	proline dipeptidase activity
NDN12_RS12950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NDN12_RS12965	COG3384	dioxygenase
NDN12_RS12975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NDN12_RS12980	COG2878	Part of a membrane complex involved in electron transport
NDN12_RS12985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDN12_RS13010	COG0768	penicillin binding
NDN12_RS13015	COG0742	ribosomal rna small subunit methyltransferase
NDN12_RS13040	COG0616	signal peptide processing
NDN12_RS13045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NDN12_RS13055	COG0573	inorganic phosphate transmembrane transporter activity
NDN12_RS13060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NDN12_RS13075	COG1113	amino acid transport
NDN12_RS13080	COG3961	Belongs to the TPP enzyme family
NDN12_RS13085	COG1522	sequence-specific DNA binding
NDN12_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
NDN12_RS13100	COG0076	glutamate decarboxylase activity
NDN12_RS13105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NDN12_RS13115	COG4772	TonB-dependent receptor
NDN12_RS13120	COG4772	TonB-dependent receptor
NDN12_RS13150	COG1309	transcriptional regulator
NDN12_RS13160	COG0783	Belongs to the Dps family
NDN12_RS13170	COG0564	pseudouridine synthase activity
NDN12_RS13185	COG0352	thiamine-phosphate diphosphorylase activity
NDN12_RS13195	COG3025	triphosphatase activity
NDN12_RS13210	COG0612	Peptidase, M16
NDN12_RS13240	COG1187	pseudouridine synthase activity
NDN12_RS13270	COG2351	hydroxyisourate hydrolase activity
NDN12_RS13280	COG1686	Belongs to the peptidase S11 family
NDN12_RS13285	COG1252	NADH dehydrogenase
NDN12_RS13295	COG0415	Belongs to the DNA photolyase family
NDN12_RS13310	COG1215	transferase activity, transferring glycosyl groups
NDN12_RS13340	COG2070	2-Nitropropane dioxygenase
NDN12_RS13370	COG0745	RESPONSE REGULATOR receiver
NDN12_RS13375	COG5002	protein histidine kinase activity
NDN12_RS13380	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NDN12_RS13385	COG4181	ATPase activity
NDN12_RS13400	COG0288	reversible hydration of carbon dioxide
NDN12_RS13415	COG4771	TonB-dependent receptor
NDN12_RS13435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NDN12_RS13445	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NDN12_RS13480	COG1597	lipid kinase activity
NDN12_RS13485	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NDN12_RS13515	COG2388	GCN5-related N-acetyl-transferase
NDN12_RS13555	COG1215	transferase activity, transferring glycosyl groups
NDN12_RS13560	COG0726	polysaccharide deacetylase
NDN12_RS13560	COG1649	PFAM Uncharacterised BCR, COG1649
NDN12_RS13575	COG4681	YaeQ
NDN12_RS13580	COG0523	cobalamin synthesis protein
NDN12_RS13590	COG1607	acyl-coa hydrolase
NDN12_RS13610	COG0583	DNA-binding transcription factor activity
NDN12_RS13620	COG1279	arginine transmembrane transporter activity
NDN12_RS13650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NDN12_RS13685	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NDN12_RS13700	COG0741	lytic transglycosylase activity
NDN12_RS13705	COG0501	Belongs to the peptidase M48B family
NDN12_RS13715	COG2239	Acts as a magnesium transporter
NDN12_RS13730	COG0584	glycerophosphoryl diester phosphodiesterase
NDN12_RS13755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDN12_RS13760	COG2304	oxidoreductase activity
NDN12_RS13770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NDN12_RS13775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDN12_RS13800	COG0505	Belongs to the CarA family
NDN12_RS13830	COG0589	response to stress
NDN12_RS13865	COG2321	neutral zinc metallopeptidase
NDN12_RS13870	COG2354	Protein conserved in bacteria
NDN12_RS13880	COG1585	Membrane protein implicated in regulation of membrane protease activity
NDN12_RS13885	COG2268	Band 7 protein
NDN12_RS13910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDN12_RS13930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NDN12_RS13935	COG1053	succinate dehydrogenase
NDN12_RS13940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NDN12_RS13945	COG2009	succinate dehydrogenase
NDN12_RS13965	COG1054	Belongs to the UPF0176 family
NDN12_RS13970	COG0586	Pfam SNARE associated Golgi protein
NDN12_RS13975	COG0583	DNA-binding transcription factor activity
NDN12_RS13980	COG1280	lysine exporter protein (LysE YggA)
NDN12_RS14000	COG2921	Belongs to the UPF0250 family
NDN12_RS14010	COG0321	lipoyl(octanoyl) transferase activity
NDN12_RS14025	COG0531	amino acid
NDN12_RS14035	COG1733	regulation of RNA biosynthetic process
NDN12_RS14045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NDN12_RS14050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDN12_RS14050	COG1648	precorrin-2 dehydrogenase activity
NDN12_RS14065	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NDN12_RS14095	COG0671	phosphoesterase, PA-phosphatase related
NDN12_RS14100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDN12_RS14110	COG1538	Outer membrane efflux protein
NDN12_RS14115	COG0393	Putative heavy-metal-binding
NDN12_RS14120	COG0393	Putative heavy-metal-binding
NDN12_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS14150	COG0525	valine-tRNA ligase activity
NDN12_RS14160	COG1943	Transposase
NDN12_RS14180	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS14185	COG2610	gluconate transmembrane transporter activity
NDN12_RS14190	COG0583	DNA-binding transcription factor activity
NDN12_RS14205	COG2031	fatty acid transporter
NDN12_RS14210	COG0004	ammonium transporteR
NDN12_RS14220	COG0765	amino acid transport
NDN12_RS14225	COG0765	amino acid transport
NDN12_RS14230	COG1126	abc transporter atp-binding protein
NDN12_RS14245	COG0642	Histidine kinase
NDN12_RS14250	COG0745	RESPONSE REGULATOR receiver
NDN12_RS14255	COG2194	sulfuric ester hydrolase activity
NDN12_RS14275	COG1752	Esterase of the alpha-beta hydrolase superfamily
NDN12_RS14290	COG2315	Protein conserved in bacteria
NDN12_RS14295	COG0142	geranyltranstransferase activity
NDN12_RS14305	COG1113	amino acid transport
NDN12_RS14315	COG0174	glutamine synthetase
NDN12_RS14325	COG4771	TonB-dependent receptor
NDN12_RS14335	COG0671	phosphoesterase, PA-phosphatase related
NDN12_RS14345	COG2851	Citrate transporter
NDN12_RS14350	COG2207	Transcriptional regulator
NDN12_RS14375	COG0745	RESPONSE REGULATOR receiver
NDN12_RS14380	COG2205	protein histidine kinase activity
NDN12_RS14385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NDN12_RS14390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NDN12_RS14395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NDN12_RS14410	COG0560	Phosphoserine phosphatase
NDN12_RS14420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDN12_RS14430	COG1530	ribonuclease E activity
NDN12_RS14435	COG0424	maF-like protein
NDN12_RS14445	COG1792	Involved in formation and maintenance of cell shape
NDN12_RS14450	COG1077	Cell shape determining protein MreB Mrl
NDN12_RS14455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDN12_RS14465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDN12_RS14520	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NDN12_RS14525	COG1752	Esterase of the alpha-beta hydrolase superfamily
NDN12_RS14530	COG1115	amino acid carrier protein
NDN12_RS14535	COG0786	glutamate:sodium symporter activity
NDN12_RS14550	COG2814	Major facilitator Superfamily
NDN12_RS14555	COG1289	transmembrane transporter activity
NDN12_RS14565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDN12_RS14610	COG1376	ErfK ybiS ycfS ynhG family protein
NDN12_RS14615	COG2832	Protein of unknown function (DUF454)
NDN12_RS14630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDN12_RS14645	COG0840	transmembrane signaling receptor activity
NDN12_RS14675	COG3422	double-strand break repair
NDN12_RS14680	COG2824	Alkylphosphonate utilization operon protein PhnA
NDN12_RS14685	COG3189	MarR family transcriptional regulator
NDN12_RS14700	COG0354	folic acid binding
NDN12_RS14715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NDN12_RS14725	COG4772	TonB-dependent receptor
NDN12_RS14750	COG1217	gtp-binding protein TYPA
NDN12_RS14755	COG2233	PERMEase
NDN12_RS14765	COG0833	amino acid
NDN12_RS14770	COG1690	Belongs to the RtcB family
NDN12_RS14780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NDN12_RS14780	COG2885	chlorophyll binding
NDN12_RS14785	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NDN12_RS14785	COG2885	chlorophyll binding
NDN12_RS14795	COG0183	Belongs to the thiolase family
NDN12_RS14815	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDN12_RS14830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NDN12_RS14835	COG2207	Transcriptional regulator
NDN12_RS14865	COG0183	Belongs to the thiolase family
NDN12_RS14870	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDN12_RS14870	COG1024	Enoyl-CoA hydratase
NDN12_RS14890	COG2153	protein acetylation
NDN12_RS14900	COG1272	protein, Hemolysin III
NDN12_RS14905	COG0477	Major facilitator Superfamily
NDN12_RS14925	COG0450	alkyl hydroperoxide reductase
NDN12_RS14950	COG0285	dihydrofolate synthase activity
NDN12_RS15010	COG4206	TonB-dependent receptor
NDN12_RS15015	COG2096	Adenosyltransferase
NDN12_RS15035	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NDN12_RS15045	COG0745	RESPONSE REGULATOR receiver
NDN12_RS15050	COG2205	protein histidine kinase activity
NDN12_RS15060	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS15065	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS15115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NDN12_RS15145	COG1442	glycosyl transferase family 8
NDN12_RS15145	COG1216	Glycosyl transferase, family 2
NDN12_RS15195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NDN12_RS15200	COG5002	protein histidine kinase activity
NDN12_RS15245	COG1862	Preprotein translocase
NDN12_RS15255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NDN12_RS15325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NDN12_RS15330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NDN12_RS15335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NDN12_RS15345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NDN12_RS15350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NDN12_RS15360	COG0625	glutathione transferase activity
NDN12_RS15365	COG2969	positive regulation of protein catabolic process
NDN12_RS15420	COG4770	biotin carboxylase activity
NDN12_RS15430	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS15435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NDN12_RS15450	COG1309	transcriptional regulator
NDN12_RS15465	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS15520	COG1183	phosphatidylcholine synthase activity
NDN12_RS15525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NDN12_RS15555	COG0739	heme binding
NDN12_RS15555	COG0741	lytic transglycosylase activity
NDN12_RS15555	COG1196	nuclear chromosome segregation
NDN12_RS15565	COG1702	phosphate starvation-inducible protein PhoH
NDN12_RS15600	COG3878	Protein conserved in bacteria
NDN12_RS15645	COG0788	formyltetrahydrofolate deformylase activity
NDN12_RS15670	COG4651	solute:proton antiporter activity
NDN12_RS15670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDN12_RS15700	COG0210	DNA helicase
NDN12_RS15725	COG1733	regulation of RNA biosynthetic process
NDN12_RS15735	COG2900	Belongs to the SlyX family
NDN12_RS15740	COG0488	(ABC) transporter
NDN12_RS15750	COG1560	Kdo2-lipid A biosynthetic process
NDN12_RS15825	COG0473	3-isopropylmalate dehydrogenase activity
NDN12_RS15840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDN12_RS15850	COG0583	DNA-binding transcription factor activity
NDN12_RS15870	COG0494	nUDIX hydrolase
NDN12_RS15885	COG0753	catalase activity
NDN12_RS15905	COG0583	DNA-binding transcription factor activity
NDN12_RS15910	COG0625	glutathione transferase activity
NDN12_RS15920	COG0546	phosphoglycolate phosphatase activity
NDN12_RS15935	COG1530	ribonuclease E activity
NDN12_RS15940	COG0318	PFAM AMP-dependent synthetase and ligase
NDN12_RS15955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NDN12_RS15965	COG0534	Mate efflux family protein
NDN12_RS15970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDN12_RS16000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDN12_RS16015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NDN12_RS16015	COG0493	'glutamate synthase
NDN12_RS16025	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NDN12_RS16035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDN12_RS16050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NDN12_RS16060	COG0644	oxidoreductase
NDN12_RS16060	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NDN12_RS16065	COG0425	Belongs to the sulfur carrier protein TusA family
NDN12_RS16070	COG4535	Mg2 and Co2 transporter CorC
NDN12_RS16075	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NDN12_RS16080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDN12_RS16105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NDN12_RS16110	COG0475	glutathione-regulated potassium exporter activity
NDN12_RS16110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDN12_RS16135	COG0789	Transcriptional regulator
NDN12_RS16140	COG0598	Magnesium transport protein CorA
NDN12_RS16145	COG1301	dicarboxylic acid transport
NDN12_RS16150	COG1185	polyribonucleotide nucleotidyltransferase activity
NDN12_RS16155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NDN12_RS16160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NDN12_RS16165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NDN12_RS16170	COG1074	ATP-dependent DNA helicase activity
NDN12_RS16175	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NDN12_RS16200	COG2226	methyltransferase
NDN12_RS16210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDN12_RS16215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDN12_RS16230	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NDN12_RS16245	COG2111	Na H antiporter
NDN12_RS16245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NDN12_RS16250	COG1006	Multisubunit Na H antiporter MnhC subunit
NDN12_RS16255	COG0651	ATP synthesis coupled electron transport
NDN12_RS16260	COG1863	multisubunit Na H antiporter MnhE subunit
NDN12_RS16265	COG2212	antiporter activity
NDN12_RS16270	COG1320	monovalent cation:proton antiporter activity
NDN12_RS16280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NDN12_RS16290	COG0195	Participates in both transcription termination and antitermination
NDN12_RS16315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NDN12_RS16340	COG0237	dephospho-CoA kinase activity
NDN12_RS16350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDN12_RS16355	COG3123	guanosine phosphorylase activity
NDN12_RS16360	COG0497	DNA recombination
NDN12_RS16370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NDN12_RS16400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDN12_RS16455	COG1132	(ABC) transporter
NDN12_RS16465	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NDN12_RS16485	COG0326	Molecular chaperone. Has ATPase activity
NDN12_RS16500	COG2056	Na+-H+ antiporter family
NDN12_RS16550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NDN12_RS16600	COG0546	phosphoglycolate phosphatase activity
NDN12_RS16605	COG1716	ATPase activity
NDN12_RS16650	COG0181	hydroxymethylbilane synthase activity
NDN12_RS16660	COG3275	phosphorelay sensor kinase activity
NDN12_RS16685	COG0494	nUDIX hydrolase
NDN12_RS16695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NDN12_RS16700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDN12_RS16705	COG0772	Belongs to the SEDS family
NDN12_RS16735	COG4974	Belongs to the 'phage' integrase family
NDN12_RS16740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NDN12_RS16750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NDN12_RS16770	COG2197	response regulator
NDN12_RS16785	COG0793	Belongs to the peptidase S41A family
NDN12_RS16790	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NDN12_RS16795	COG0795	lipopolysaccharide-transporting ATPase activity
NDN12_RS16800	COG0795	lipopolysaccharide-transporting ATPase activity
NDN12_RS16835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDN12_RS16835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDN12_RS16845	COG0004	ammonium transporteR
NDN12_RS16850	COG0347	Belongs to the P(II) protein family
NDN12_RS16885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NDN12_RS16900	COG0318	PFAM AMP-dependent synthetase and ligase
NDN12_RS16910	COG2860	membrane
NDN12_RS16920	COG1253	flavin adenine dinucleotide binding
NDN12_RS16935	COG2814	Major facilitator Superfamily
NDN12_RS16950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDN12_RS16955	COG0745	RESPONSE REGULATOR receiver
NDN12_RS16960	COG2205	protein histidine kinase activity
NDN12_RS16965	COG4452	Inner membrane protein CreD
NDN12_RS17000	COG2814	Major facilitator Superfamily
NDN12_RS17010	COG0789	Transcriptional regulator
NDN12_RS17020	COG0655	NAD(P)H dehydrogenase (quinone) activity
NDN12_RS17040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NDN12_RS17075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NDN12_RS17085	COG2814	Major facilitator Superfamily
NDN12_RS17090	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS17095	COG0583	DNA-binding transcription factor activity
NDN12_RS17115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDN12_RS17120	COG3162	membrane
NDN12_RS17125	COG2205	protein histidine kinase activity
NDN12_RS17125	COG0784	Response regulator, receiver
NDN12_RS17150	COG1652	LysM domain
NDN12_RS17155	COG0758	DNA mediated transformation
NDN12_RS17170	COG1309	transcriptional regulator
NDN12_RS17175	COG2814	Major facilitator Superfamily
NDN12_RS17190	COG0386	Belongs to the glutathione peroxidase family
NDN12_RS17205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NDN12_RS17210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NDN12_RS17220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NDN12_RS17260	COG1121	(ABC) transporter
NDN12_RS17265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NDN12_RS17270	COG1280	lysine exporter protein (LysE YggA)
NDN12_RS17275	COG2837	iron assimilation
NDN12_RS17315	COG0735	belongs to the Fur family
NDN12_RS17330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NDN12_RS17330	COG0519	Catalyzes the synthesis of GMP from XMP
NDN12_RS17335	COG4399	Belongs to the UPF0754 family
NDN12_RS17340	COG3111	PFAM Bacterial OB fold (BOF) protein
NDN12_RS17345	COG2259	Doxx family
NDN12_RS17350	COG0586	Pfam SNARE associated Golgi protein
NDN12_RS17365	COG1192	Involved in chromosome partitioning
NDN12_RS17375	COG0271	Belongs to the BolA IbaG family
NDN12_RS17390	COG0477	Major facilitator Superfamily
NDN12_RS17400	COG1024	Enoyl-CoA hydratase
NDN12_RS17405	COG1960	acyl-CoA dehydrogenase activity
NDN12_RS17410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NDN12_RS17430	COG1113	amino acid transport
NDN12_RS17435	COG0251	oxidation-reduction process
NDN12_RS17460	COG0456	acetyltransferase
NDN12_RS17465	COG0564	pseudouridine synthase activity
NDN12_RS17520	COG1802	Transcriptional regulator
NDN12_RS17525	COG1448	Aminotransferase
NDN12_RS17530	COG0277	FAD linked oxidase domain protein
NDN12_RS17540	COG2186	Transcriptional regulator
NDN12_RS17550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDN12_RS17555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NDN12_RS17570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NDN12_RS17580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NDN12_RS17590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NDN12_RS17620	COG0438	transferase activity, transferring glycosyl groups
NDN12_RS17640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NDN12_RS17645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NDN12_RS17650	COG1596	polysaccharide export
NDN12_RS17680	COG0728	peptidoglycan biosynthetic process
NDN12_RS17685	COG3023	N-Acetylmuramoyl-L-alanine amidase
NDN12_RS17745	COG0546	phosphoglycolate phosphatase activity
NDN12_RS17750	COG1028	Short-chain dehydrogenase reductase Sdr
NDN12_RS17760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NDN12_RS17760	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NDN12_RS17765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDN12_RS17770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDN12_RS17775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDN12_RS17780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDN12_RS17785	COG1116	anion transmembrane transporter activity
NDN12_RS17790	COG1309	transcriptional regulator
NDN12_RS17810	COG1040	competence protein
NDN12_RS17815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NDN12_RS17825	COG0196	riboflavin kinase activity
NDN12_RS17830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NDN12_RS17840	COG1047	Peptidyl-prolyl cis-trans
NDN12_RS17885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDN12_RS17890	COG0657	acetylesterase activity
NDN12_RS17905	COG0583	DNA-binding transcription factor activity
NDN12_RS17915	COG0443	Heat shock 70 kDa protein
NDN12_RS17920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NDN12_RS17950	COG2951	lytic endotransglycosylase activity
NDN12_RS17955	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NDN12_RS17970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NDN12_RS17995	COG0583	DNA-binding transcription factor activity
NDN12_RS18005	COG0861	Integral membrane protein TerC family
NDN12_RS18020	COG0754	glutathionylspermidine amidase activity
NDN12_RS18040	COG0402	S-adenosylhomocysteine deaminase activity
NDN12_RS18050	COG2261	transglycosylase associated protein
NDN12_RS18075	COG0706	membrane insertase activity