locus-tag	class	description
MTO68_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MTO68_RS00010	COG0592	DNA-directed DNA polymerase activity
MTO68_RS00020	COG0187	DNA topoisomerase II activity
MTO68_RS00030	COG0488	(ABC) transporter
MTO68_RS00040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MTO68_RS00045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MTO68_RS00050	COG0596	Alpha beta hydrolase
MTO68_RS00070	COG0657	acetylesterase activity
MTO68_RS00075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MTO68_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS00120	COG3738	Protein conserved in bacteria
MTO68_RS00125	COG0733	neurotransmitter:sodium symporter activity
MTO68_RS00135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MTO68_RS00135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MTO68_RS00140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MTO68_RS00155	COG0129	dihydroxy-acid dehydratase activity
MTO68_RS00175	COG0174	glutamine synthetase
MTO68_RS00190	COG1794	racemase activity, acting on amino acids and derivatives
MTO68_RS00195	COG1047	Peptidyl-prolyl cis-trans
MTO68_RS00200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MTO68_RS00205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MTO68_RS00210	COG0196	riboflavin kinase activity
MTO68_RS00225	COG2233	PERMEase
MTO68_RS00250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MTO68_RS00300	COG2814	Major facilitator Superfamily
MTO68_RS00305	COG0656	L-ascorbic acid biosynthetic process
MTO68_RS00310	COG0583	DNA-binding transcription factor activity
MTO68_RS00325	COG1064	alcohol dehydrogenase
MTO68_RS00330	COG2818	Glycosylase
MTO68_RS00345	COG1194	a g-specific adenine glycosylase
MTO68_RS00360	COG5487	UPF0391 membrane protein
MTO68_RS00365	COG2983	Belongs to the UPF0260 family
MTO68_RS00375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MTO68_RS00415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTO68_RS00420	COG1335	isochorismatase
MTO68_RS00425	COG0385	Bile acid
MTO68_RS00430	COG1683	Conserved Protein
MTO68_RS00445	COG0640	Transcriptional regulator
MTO68_RS00450	COG1230	cation diffusion facilitator family transporter
MTO68_RS00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MTO68_RS00465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MTO68_RS00470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MTO68_RS00475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MTO68_RS00480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MTO68_RS00495	COG3830	Belongs to the UPF0237 family
MTO68_RS00495	COG0560	Phosphoserine phosphatase
MTO68_RS00560	COG0534	Mate efflux family protein
MTO68_RS00565	COG0436	Aminotransferase
MTO68_RS00595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MTO68_RS00610	COG2733	membrane
MTO68_RS00630	COG2918	glutathione biosynthetic process
MTO68_RS00635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MTO68_RS00650	COG3150	esterase
MTO68_RS00725	COG3706	GGDEF domain
MTO68_RS00730	COG3706	GGDEF domain
MTO68_RS00745	COG1393	Belongs to the ArsC family
MTO68_RS00750	COG0708	Exodeoxyribonuclease III
MTO68_RS00765	COG2720	vancomycin resistance protein
MTO68_RS00770	COG2226	methyltransferase
MTO68_RS00785	COG0189	ligase activity
MTO68_RS00795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MTO68_RS00805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MTO68_RS00820	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MTO68_RS00845	COG2119	membrane
MTO68_RS00850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTO68_RS00850	COG0426	domain, Protein
MTO68_RS00870	COG0259	pyridoxamine-phosphate oxidase activity
MTO68_RS00875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MTO68_RS00880	COG3118	belongs to the thioredoxin family
MTO68_RS00930	COG2267	carboxylic ester hydrolase activity
MTO68_RS00935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MTO68_RS00955	COG0352	thiamine-phosphate diphosphorylase activity
MTO68_RS00955	COG0351	phosphomethylpyrimidine kinase
MTO68_RS00955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MTO68_RS00965	COG2814	Major facilitator Superfamily
MTO68_RS00970	COG0629	single-stranded DNA binding
MTO68_RS00995	COG0583	DNA-binding transcription factor activity
MTO68_RS01000	COG1335	isochorismatase
MTO68_RS01010	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MTO68_RS01035	COG3177	Filamentation induced by cAMP protein fic
MTO68_RS01080	COG3158	transport of potassium into the cell
MTO68_RS01095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTO68_RS01115	COG0165	Argininosuccinate lyase
MTO68_RS01120	COG3275	phosphorelay sensor kinase activity
MTO68_RS01130	COG0181	hydroxymethylbilane synthase activity
MTO68_RS01220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MTO68_RS01235	COG0081	regulation of translation
MTO68_RS01245	COG0222	ribosome binding
MTO68_RS01250	COG0085	RNA polymerase activity
MTO68_RS01255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MTO68_RS01280	COG2056	Na+-H+ antiporter family
MTO68_RS01295	COG0326	Molecular chaperone. Has ATPase activity
MTO68_RS01310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MTO68_RS01345	COG0183	Belongs to the thiolase family
MTO68_RS01350	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTO68_RS01350	COG1024	Enoyl-CoA hydratase
MTO68_RS01395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MTO68_RS01425	COG0795	lipopolysaccharide-transporting ATPase activity
MTO68_RS01430	COG0795	lipopolysaccharide-transporting ATPase activity
MTO68_RS01435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MTO68_RS01440	COG0793	Belongs to the peptidase S41A family
MTO68_RS01455	COG2197	response regulator
MTO68_RS01460	COG1686	Belongs to the peptidase S11 family
MTO68_RS01475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MTO68_RS01490	COG4974	Belongs to the 'phage' integrase family
MTO68_RS01510	COG1132	(ABC) transporter
MTO68_RS01520	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTO68_RS01530	COG1289	transmembrane transporter activity
MTO68_RS01550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MTO68_RS01560	COG0497	DNA recombination
MTO68_RS01565	COG3123	guanosine phosphorylase activity
MTO68_RS01570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTO68_RS01580	COG0237	dephospho-CoA kinase activity
MTO68_RS01585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MTO68_RS01630	COG0779	Required for maturation of 30S ribosomal subunits
MTO68_RS01635	COG0195	Participates in both transcription termination and antitermination
MTO68_RS01645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MTO68_RS01655	COG1704	LemA family
MTO68_RS01660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MTO68_RS01680	COG3307	-O-antigen
MTO68_RS01700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MTO68_RS01705	COG1758	RNA polymerase activity
MTO68_RS01710	COG0194	GDP metabolic process
MTO68_RS01755	COG0228	four-way junction DNA binding
MTO68_RS01760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MTO68_RS01770	COG0335	large ribosomal subunit rRNA binding
MTO68_RS01785	COG5380	lipid catabolic process
MTO68_RS01790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MTO68_RS01815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MTO68_RS01825	COG5006	permease, DMT superfamily
MTO68_RS01830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTO68_RS01835	COG0277	FAD linked oxidase domain protein
MTO68_RS01875	COG2814	Major facilitator Superfamily
MTO68_RS01885	COG1289	transmembrane transporter activity
MTO68_RS01895	COG2032	superoxide dismutase activity
MTO68_RS01900	COG0628	permease
MTO68_RS01915	COG2226	methyltransferase
MTO68_RS01960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MTO68_RS01985	COG1196	nuclear chromosome segregation
MTO68_RS02005	COG0751	glycine-tRNA ligase activity
MTO68_RS02010	COG0752	glycyl-tRNA synthetase alpha subunit
MTO68_RS02035	COG0277	FAD linked oxidase domain protein
MTO68_RS02045	COG0517	IMP dehydrogenase activity
MTO68_RS02050	COG1983	PspC domain protein
MTO68_RS02090	COG0318	PFAM AMP-dependent synthetase and ligase
MTO68_RS02095	COG1530	ribonuclease E activity
MTO68_RS02100	COG0564	pseudouridine synthase activity
MTO68_RS02105	COG0546	phosphoglycolate phosphatase activity
MTO68_RS02110	COG2378	regulation of single-species biofilm formation
MTO68_RS02125	COG0583	DNA-binding transcription factor activity
MTO68_RS02165	COG0753	catalase activity
MTO68_RS02175	COG1309	transcriptional regulator
MTO68_RS02195	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS02220	COG0494	nUDIX hydrolase
MTO68_RS02235	COG0583	DNA-binding transcription factor activity
MTO68_RS02250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MTO68_RS02265	COG0473	3-isopropylmalate dehydrogenase activity
MTO68_RS02275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MTO68_RS02290	COG0252	asparaginase activity
MTO68_RS02325	COG1560	Kdo2-lipid A biosynthetic process
MTO68_RS02350	COG0488	(ABC) transporter
MTO68_RS02355	COG2900	Belongs to the SlyX family
MTO68_RS02360	COG0583	DNA-binding transcription factor activity
MTO68_RS02380	COG1984	allophanate hydrolase subunit 2
MTO68_RS02385	COG4770	biotin carboxylase activity
MTO68_RS02395	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS02400	COG1733	regulation of RNA biosynthetic process
MTO68_RS02430	COG1929	Belongs to the glycerate kinase type-1 family
MTO68_RS02435	COG0210	DNA helicase
MTO68_RS02455	COG4651	solute:proton antiporter activity
MTO68_RS02455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MTO68_RS02480	COG0788	formyltetrahydrofolate deformylase activity
MTO68_RS02520	COG1607	acyl-coa hydrolase
MTO68_RS02535	COG1666	GTP binding
MTO68_RS02540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTO68_RS02555	COG2350	Protein conserved in bacteria
MTO68_RS02565	COG0613	PHP domain protein
MTO68_RS02575	COG1702	phosphate starvation-inducible protein PhoH
MTO68_RS02580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MTO68_RS02585	COG0739	heme binding
MTO68_RS02585	COG1196	nuclear chromosome segregation
MTO68_RS02585	COG0741	lytic transglycosylase activity
MTO68_RS02595	COG0039	L-malate dehydrogenase activity
MTO68_RS02615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MTO68_RS02620	COG1183	phosphatidylcholine synthase activity
MTO68_RS02680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MTO68_RS02685	COG3878	Protein conserved in bacteria
MTO68_RS02725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MTO68_RS02740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MTO68_RS02760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTO68_RS02760	COG2813	Specifically methylates the guanine in position
MTO68_RS02770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MTO68_RS02785	COG4774	siderophore transport
MTO68_RS02795	COG0740	serine-type endopeptidase activity
MTO68_RS02840	COG0857	belongs to the CobB CobQ family
MTO68_RS02840	COG0280	phosphate acetyltransferase
MTO68_RS02845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MTO68_RS02870	COG0793	Belongs to the peptidase S41A family
MTO68_RS02880	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MTO68_RS02895	COG0084	hydrolase, TatD family'
MTO68_RS02905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MTO68_RS02925	COG0583	DNA-binding transcription factor activity
MTO68_RS02930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MTO68_RS03020	COG0640	Transcriptional regulator
MTO68_RS03030	COG0798	PFAM Bile acid sodium symporter
MTO68_RS03035	COG0431	NADPH-dependent FMN reductase
MTO68_RS03040	COG0492	ferredoxin-NADP+ reductase activity
MTO68_RS03045	COG2072	flavoprotein involved in K transport
MTO68_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS03065	COG0583	DNA-binding transcription factor activity
MTO68_RS03080	COG0583	DNA-binding transcription factor activity
MTO68_RS03085	COG2186	Transcriptional regulator
MTO68_RS03090	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS03100	COG4948	Mandelate Racemase Muconate Lactonizing
MTO68_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS03120	COG0738	Major facilitator superfamily
MTO68_RS03140	COG0668	transmembrane transport
MTO68_RS03155	COG2814	Major facilitator Superfamily
MTO68_RS03205	COG1862	Preprotein translocase
MTO68_RS03225	COG3201	nicotinamide mononucleotide transporter
MTO68_RS03245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MTO68_RS03255	COG0582	viral genome integration into host DNA
MTO68_RS03260	COG2826	transposase and inactivated derivatives, IS30 family
MTO68_RS03280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MTO68_RS03280	COG0784	Response regulator, receiver
MTO68_RS03295	COG2826	transposase and inactivated derivatives, IS30 family
MTO68_RS03390	COG2205	protein histidine kinase activity
MTO68_RS03395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MTO68_RS03420	COG0438	transferase activity, transferring glycosyl groups
MTO68_RS03440	COG3306	glycosyltransferase involved in LPS biosynthesis
MTO68_RS03445	COG3306	glycosyltransferase involved in LPS biosynthesis
MTO68_RS03460	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MTO68_RS03515	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS03520	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS03545	COG0277	FAD linked oxidase domain protein
MTO68_RS03575	COG0625	glutathione transferase activity
MTO68_RS03585	COG1238	metal cluster binding
MTO68_RS03600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MTO68_RS03640	COG0072	phenylalanine-tRNA ligase activity
MTO68_RS03645	COG0776	regulation of translation
MTO68_RS03665	COG0248	Ppx GppA phosphatase
MTO68_RS03675	COG0037	tRNA processing
MTO68_RS03700	COG0183	Belongs to the thiolase family
MTO68_RS03725	COG1690	Belongs to the RtcB family
MTO68_RS03730	COG0833	amino acid
MTO68_RS03740	COG2233	PERMEase
MTO68_RS03745	COG1217	gtp-binding protein TYPA
MTO68_RS03750	COG1970	mechanosensitive ion channel activity
MTO68_RS03760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MTO68_RS03770	COG3659	wide pore channel activity
MTO68_RS03775	COG4772	TonB-dependent receptor
MTO68_RS03780	COG1902	pentaerythritol trinitrate reductase activity
MTO68_RS03830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MTO68_RS03890	COG2969	positive regulation of protein catabolic process
MTO68_RS03895	COG0625	glutathione transferase activity
MTO68_RS03905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MTO68_RS03910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MTO68_RS03920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MTO68_RS03925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MTO68_RS03930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MTO68_RS03955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MTO68_RS03965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MTO68_RS03970	COG1408	metallophosphoesterase
MTO68_RS04000	COG2824	Alkylphosphonate utilization operon protein PhnA
MTO68_RS04005	COG2197	response regulator
MTO68_RS04010	COG0477	Major facilitator Superfamily
MTO68_RS04045	COG4166	transmembrane transport
MTO68_RS04050	COG4166	transmembrane transport
MTO68_RS04085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MTO68_RS04090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MTO68_RS04100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MTO68_RS04105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTO68_RS04180	COG2826	transposase and inactivated derivatives, IS30 family
MTO68_RS04240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTO68_RS04250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MTO68_RS04250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTO68_RS04255	COG0745	RESPONSE REGULATOR receiver
MTO68_RS04260	COG2205	protein histidine kinase activity
MTO68_RS04280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTO68_RS04300	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MTO68_RS04310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MTO68_RS04315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTO68_RS04325	COG0713	ATP synthesis coupled electron transport
MTO68_RS04330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MTO68_RS04335	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTO68_RS04345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MTO68_RS04360	COG0583	DNA-binding transcription factor activity
MTO68_RS04370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTO68_RS04380	COG2050	protein possibly involved in aromatic compounds catabolism
MTO68_RS04385	COG1566	PFAM secretion protein HlyD family protein
MTO68_RS04390	COG2814	Major facilitator Superfamily
MTO68_RS04400	COG2852	Protein conserved in bacteria
MTO68_RS04410	COG5295	Hep Hag repeat protein
MTO68_RS04410	COG5295	Hep Hag repeat protein
MTO68_RS04415	COG0306	phosphate transporter
MTO68_RS04425	COG3153	acetyltransferase
MTO68_RS04430	COG0175	sulfate reduction
MTO68_RS04475	COG2851	Citrate transporter
MTO68_RS04480	COG1253	flavin adenine dinucleotide binding
MTO68_RS04500	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MTO68_RS04505	COG2894	cell division
MTO68_RS04510	COG0850	regulation of cytokinetic process
MTO68_RS04520	COG0204	Acyl-transferase
MTO68_RS04525	COG2885	chlorophyll binding
MTO68_RS04535	COG0756	dUTP diphosphatase activity
MTO68_RS04540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTO68_RS04545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MTO68_RS04555	COG0121	glutamine amidotransferase
MTO68_RS04570	COG2914	Belongs to the UPF0125 (RnfH) family
MTO68_RS04575	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MTO68_RS04580	COG0735	belongs to the Fur family
MTO68_RS04600	COG1968	undecaprenyl-diphosphatase activity
MTO68_RS04630	COG0420	3'-5' exonuclease activity
MTO68_RS04665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MTO68_RS04680	COG0786	glutamate:sodium symporter activity
MTO68_RS04685	COG2059	Chromate
MTO68_RS04690	COG1752	Esterase of the alpha-beta hydrolase superfamily
MTO68_RS04695	COG1607	acyl-coa hydrolase
MTO68_RS04725	COG0523	cobalamin synthesis protein
MTO68_RS04730	COG4681	YaeQ
MTO68_RS04750	COG0726	polysaccharide deacetylase
MTO68_RS04750	COG1649	PFAM Uncharacterised BCR, COG1649
MTO68_RS04755	COG1215	transferase activity, transferring glycosyl groups
MTO68_RS04785	COG3755	Protein conserved in bacteria
MTO68_RS04790	COG1309	transcriptional regulator
MTO68_RS04800	COG1024	Enoyl-CoA hydratase
MTO68_RS04815	COG4771	TonB-dependent receptor
MTO68_RS04875	COG1113	amino acid transport
MTO68_RS04880	COG2828	Protein conserved in bacteria
MTO68_RS04885	COG2199	diguanylate cyclase activity
MTO68_RS04885	COG2203	Gaf domain
MTO68_RS04890	COG0142	geranyltranstransferase activity
MTO68_RS04905	COG1752	Esterase of the alpha-beta hydrolase superfamily
MTO68_RS04915	COG2814	Major facilitator Superfamily
MTO68_RS04920	COG2194	sulfuric ester hydrolase activity
MTO68_RS04930	COG0642	Histidine kinase
MTO68_RS04945	COG0004	ammonium transporteR
MTO68_RS04970	COG2852	Protein conserved in bacteria
MTO68_RS04985	COG0525	valine-tRNA ligase activity
MTO68_RS04995	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS05010	COG0393	Putative heavy-metal-binding
MTO68_RS05015	COG0393	Putative heavy-metal-binding
MTO68_RS05020	COG1538	Outer membrane efflux protein
MTO68_RS05030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTO68_RS05035	COG0671	phosphoesterase, PA-phosphatase related
MTO68_RS05050	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MTO68_RS05060	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MTO68_RS05065	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MTO68_RS05075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MTO68_RS05080	COG1648	precorrin-2 dehydrogenase activity
MTO68_RS05080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MTO68_RS05085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MTO68_RS05115	COG0531	amino acid
MTO68_RS05130	COG0321	lipoyl(octanoyl) transferase activity
MTO68_RS05135	COG2921	Belongs to the UPF0250 family
MTO68_RS05155	COG1280	lysine exporter protein (LysE YggA)
MTO68_RS05160	COG0586	Pfam SNARE associated Golgi protein
MTO68_RS05175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTO68_RS05205	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MTO68_RS05210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MTO68_RS05265	COG0564	pseudouridine synthase activity
MTO68_RS05315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MTO68_RS05320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MTO68_RS05325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MTO68_RS05385	COG0477	Major facilitator Superfamily
MTO68_RS05410	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MTO68_RS05415	COG1597	lipid kinase activity
MTO68_RS05430	COG0459	protein refolding
MTO68_RS05445	COG0584	glycerophosphoryl diester phosphodiesterase
MTO68_RS05450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTO68_RS05455	COG2239	Acts as a magnesium transporter
MTO68_RS05480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MTO68_RS05485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MTO68_RS05490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTO68_RS05510	COG1113	amino acid transport
MTO68_RS05520	COG0019	diaminopimelate decarboxylase activity
MTO68_RS05545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MTO68_RS05555	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MTO68_RS05575	COG0833	amino acid
MTO68_RS05585	COG0833	amino acid
MTO68_RS05595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MTO68_RS05600	COG0418	dihydroorotase activity
MTO68_RS05620	COG0501	Belongs to the peptidase M48B family
MTO68_RS05625	COG0741	lytic transglycosylase activity
MTO68_RS05630	COG0037	tRNA processing
MTO68_RS05640	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MTO68_RS05650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MTO68_RS05660	COG0582	viral genome integration into host DNA
MTO68_RS05735	COG1230	cation diffusion facilitator family transporter
MTO68_RS05795	COG2814	Major facilitator Superfamily
MTO68_RS05800	COG1238	metal cluster binding
MTO68_RS05810	COG4804	nuclease activity
MTO68_RS05860	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MTO68_RS05940	COG0582	viral genome integration into host DNA
MTO68_RS05955	COG3220	belongs to the UPF0276 family
MTO68_RS05965	COG1595	DNA-templated transcription, initiation
MTO68_RS05990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MTO68_RS06005	COG0642	Histidine kinase
MTO68_RS06025	COG4771	TonB-dependent receptor
MTO68_RS06050	COG1595	DNA-templated transcription, initiation
MTO68_RS06065	COG0477	Major facilitator Superfamily
MTO68_RS06085	COG1309	transcriptional regulator
MTO68_RS06125	COG3188	usher protein
MTO68_RS06195	COG1598	PFAM Uncharacterised protein family UPF0150
MTO68_RS06205	COG3539	Fimbrial protein
MTO68_RS06280	COG3539	Fimbrial protein
MTO68_RS06315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTO68_RS06320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTO68_RS06330	COG0318	PFAM AMP-dependent synthetase and ligase
MTO68_RS06345	COG2986	histidine ammonia-lyase
MTO68_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS06405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTO68_RS06405	COG1116	anion transmembrane transporter activity
MTO68_RS06415	COG2223	nitrite transmembrane transporter activity
MTO68_RS06420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTO68_RS06425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTO68_RS06430	COG0243	molybdopterin cofactor binding
MTO68_RS06440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MTO68_RS06450	COG0314	molybdopterin synthase activity
MTO68_RS06455	COG1414	Transcriptional regulator
MTO68_RS06460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MTO68_RS06465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MTO68_RS06470	COG0183	Belongs to the thiolase family
MTO68_RS06475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MTO68_RS06480	COG0596	Alpha beta hydrolase
MTO68_RS06485	COG2271	Major facilitator Superfamily
MTO68_RS06490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MTO68_RS06495	COG3485	protocatechuate 3,4-dioxygenase
MTO68_RS06500	COG3485	protocatechuate 3,4-dioxygenase
MTO68_RS06505	COG0710	3-dehydroquinate dehydratase activity
MTO68_RS06510	COG3420	alginic acid biosynthetic process
MTO68_RS06515	COG3659	wide pore channel activity
MTO68_RS06520	COG4993	Dehydrogenase
MTO68_RS06525	COG0789	Transcriptional regulator
MTO68_RS06530	COG2217	Heavy metal translocating P-type atpase
MTO68_RS06545	COG2205	protein histidine kinase activity
MTO68_RS06560	COG1923	regulation of RNA biosynthetic process
MTO68_RS06570	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MTO68_RS06575	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MTO68_RS06585	COG2205	protein histidine kinase activity
MTO68_RS06590	COG0745	RESPONSE REGULATOR receiver
MTO68_RS06615	COG2223	nitrite transmembrane transporter activity
MTO68_RS06650	COG0006	proline dipeptidase activity
MTO68_RS06675	COG2814	Major facilitator Superfamily
MTO68_RS06680	COG1733	regulation of RNA biosynthetic process
MTO68_RS06685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTO68_RS06690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTO68_RS06735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MTO68_RS06740	COG0741	lytic transglycosylase activity
MTO68_RS06740	COG1388	LysM domain
MTO68_RS06745	COG4166	transmembrane transport
MTO68_RS06750	COG4174	ABC transporter (Permease)
MTO68_RS06755	COG4239	(ABC) transporter, permease
MTO68_RS06760	COG4172	Belongs to the ABC transporter superfamily
MTO68_RS06785	COG0052	Belongs to the universal ribosomal protein uS2 family
MTO68_RS06790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MTO68_RS06860	COG2887	Belongs to the helicase family. UvrD subfamily
MTO68_RS06905	COG0305	Participates in initiation and elongation during chromosome replication
MTO68_RS06995	COG4383	Mu-like prophage protein gp29
MTO68_RS07135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MTO68_RS07160	COG2951	lytic endotransglycosylase activity
MTO68_RS07165	COG0772	Belongs to the SEDS family
MTO68_RS07180	COG0842	Transport permease protein
MTO68_RS07185	COG1131	(ABC) transporter
MTO68_RS07195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTO68_RS07275	COG1476	TRANSCRIPTIONal
MTO68_RS07400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MTO68_RS07415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MTO68_RS07450	COG2233	PERMEase
MTO68_RS07460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTO68_RS07465	COG1823	symporter activity
MTO68_RS07480	COG0612	Peptidase, M16
MTO68_RS07490	COG1720	tRNA m6t6A37 methyltransferase activity
MTO68_RS07510	COG0352	thiamine-phosphate diphosphorylase activity
MTO68_RS07560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MTO68_RS07565	COG3111	PFAM Bacterial OB fold (BOF) protein
MTO68_RS07575	COG0642	Histidine kinase
MTO68_RS07585	COG0494	nUDIX hydrolase
MTO68_RS07595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTO68_RS07600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MTO68_RS07605	COG3139	Protein of unknown function (DUF1315)
MTO68_RS07615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MTO68_RS07620	COG1301	dicarboxylic acid transport
MTO68_RS07630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MTO68_RS07640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MTO68_RS07705	COG2318	DinB family
MTO68_RS07710	COG2070	2-Nitropropane dioxygenase
MTO68_RS07775	COG1643	Atp-dependent helicase
MTO68_RS07805	COG3210	domain, Protein
MTO68_RS07810	COG2831	hemolysin activation secretion protein
MTO68_RS07815	COG2188	Transcriptional regulator
MTO68_RS07835	COG1113	amino acid transport
MTO68_RS07845	COG0010	Belongs to the arginase family
MTO68_RS07850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MTO68_RS07865	COG3706	GGDEF domain
MTO68_RS07875	COG2072	flavoprotein involved in K transport
MTO68_RS07880	COG0300	oxidoreductase activity
MTO68_RS07885	COG1280	lysine exporter protein (LysE YggA)
MTO68_RS07900	COG1136	(ABC) transporter
MTO68_RS07905	COG0658	competence protein
MTO68_RS07905	COG2333	competence protein COMEC
MTO68_RS07925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MTO68_RS07935	COG0628	permease
MTO68_RS07975	COG3634	alkyl hydroperoxide reductase activity
MTO68_RS07980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MTO68_RS07985	COG0583	DNA-binding transcription factor activity
MTO68_RS08005	COG1192	Involved in chromosome partitioning
MTO68_RS08010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MTO68_RS08015	COG0826	peptidase U32
MTO68_RS08025	COG0640	Transcriptional regulator
MTO68_RS08030	COG0798	PFAM Bile acid sodium symporter
MTO68_RS08035	COG0789	Transcriptional regulator
MTO68_RS08075	COG1022	Amp-dependent synthetase and ligase
MTO68_RS08120	COG4772	TonB-dependent receptor
MTO68_RS08130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTO68_RS08135	COG0076	glutamate decarboxylase activity
MTO68_RS08145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MTO68_RS08195	COG3188	usher protein
MTO68_RS08205	COG3121	Chaperone
MTO68_RS08220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MTO68_RS08225	COG0521	Mo-molybdopterin cofactor biosynthetic process
MTO68_RS08225	COG0315	cyclic pyranopterin monophosphate synthase activity
MTO68_RS08230	COG0303	'Molybdopterin
MTO68_RS08250	COG0243	molybdopterin cofactor binding
MTO68_RS08255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MTO68_RS08260	COG0725	ABC transporter, periplasmic molybdate-binding protein
MTO68_RS08265	COG4149	molybdate abc transporter
MTO68_RS08275	COG1301	dicarboxylic acid transport
MTO68_RS08280	COG0583	DNA-binding transcription factor activity
MTO68_RS08290	COG1794	racemase activity, acting on amino acids and derivatives
MTO68_RS08310	COG1522	sequence-specific DNA binding
MTO68_RS08325	COG1234	tRNA 3'-trailer cleavage
MTO68_RS08360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTO68_RS08375	COG0543	2 iron, 2 sulfur cluster binding
MTO68_RS08375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MTO68_RS08380	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MTO68_RS08385	COG4638	Rieske (2fe-2S)
MTO68_RS08395	COG2814	Major facilitator Superfamily
MTO68_RS08410	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTO68_RS08420	COG0154	amidase activity
MTO68_RS08435	COG4638	Rieske (2fe-2S)
MTO68_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS08455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTO68_RS08470	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS08485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTO68_RS08490	COG0183	Belongs to the thiolase family
MTO68_RS08495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MTO68_RS08500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MTO68_RS08505	COG4829	muconolactone delta-isomerase
MTO68_RS08510	COG4948	Mandelate Racemase Muconate Lactonizing
MTO68_RS08515	COG0583	DNA-binding transcription factor activity
MTO68_RS08520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MTO68_RS08525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MTO68_RS08530	COG3485	protocatechuate 3,4-dioxygenase
MTO68_RS08545	COG1294	oxidase, subunit
MTO68_RS08550	COG1271	oxidase subunit
MTO68_RS08555	COG1380	Effector of murein hydrolase LrgA
MTO68_RS08560	COG1346	cytolysis
MTO68_RS08590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MTO68_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS08605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTO68_RS08615	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS08625	COG0546	phosphoglycolate phosphatase activity
MTO68_RS08630	COG1737	Transcriptional regulator
MTO68_RS08645	COG1129	ABC transporter
MTO68_RS08650	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTO68_RS08665	COG1063	alcohol dehydrogenase
MTO68_RS08685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MTO68_RS08695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MTO68_RS08715	COG0644	oxidoreductase
MTO68_RS08715	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MTO68_RS08720	COG2814	Major facilitator Superfamily
MTO68_RS08725	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS08730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTO68_RS08750	COG2814	Major facilitator Superfamily
MTO68_RS08760	COG0183	Belongs to the thiolase family
MTO68_RS08765	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTO68_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS08775	COG1024	Enoyl-CoA hydratase
MTO68_RS08780	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS08785	COG2814	Major facilitator Superfamily
MTO68_RS08790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MTO68_RS08795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MTO68_RS08805	COG2814	Major facilitator Superfamily
MTO68_RS08815	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS08820	COG1024	Enoyl-CoA hydratase
MTO68_RS08825	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTO68_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS08835	COG2610	gluconate transmembrane transporter activity
MTO68_RS08840	COG0583	DNA-binding transcription factor activity
MTO68_RS08850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MTO68_RS08875	COG3836	Belongs to the HpcH HpaI aldolase family
MTO68_RS08880	COG4264	IucA IucC family
MTO68_RS08890	COG4264	IucA IucC family
MTO68_RS08895	COG2423	ornithine cyclodeaminase activity
MTO68_RS08900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MTO68_RS08980	COG0583	DNA-binding transcription factor activity
MTO68_RS08985	COG0473	3-isopropylmalate dehydrogenase activity
MTO68_RS08995	COG0657	acetylesterase activity
MTO68_RS09000	COG4638	Rieske (2fe-2S)
MTO68_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS09025	COG2871	sodium ion transport
MTO68_RS09060	COG5002	protein histidine kinase activity
MTO68_RS09065	COG0745	RESPONSE REGULATOR receiver
MTO68_RS09070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTO68_RS09090	COG2832	Protein of unknown function (DUF454)
MTO68_RS09100	COG1595	DNA-templated transcription, initiation
MTO68_RS09140	COG0436	Aminotransferase
MTO68_RS09155	COG2199	diguanylate cyclase activity
MTO68_RS09180	COG0556	nucleotide-excision repair
MTO68_RS09190	COG2962	Rard protein
MTO68_RS09225	COG0702	epimerase
MTO68_RS09230	COG1733	regulation of RNA biosynthetic process
MTO68_RS09245	COG2915	High frequency lysogenization protein hflD homolog
MTO68_RS09265	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MTO68_RS09270	COG1686	Belongs to the peptidase S11 family
MTO68_RS09300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MTO68_RS09305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MTO68_RS09310	COG1067	ATP-dependent peptidase activity
MTO68_RS09345	COG1509	lysine 2,3-aminomutase activity
MTO68_RS09350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MTO68_RS09355	COG1966	Carbon starvation protein
MTO68_RS09360	COG2879	small protein
MTO68_RS09375	COG0714	Associated with various cellular activities
MTO68_RS09415	COG5487	UPF0391 membrane protein
MTO68_RS09475	COG4771	TonB-dependent receptor
MTO68_RS09490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTO68_RS09495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTO68_RS09510	COG2252	PERMEase
MTO68_RS09515	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MTO68_RS09525	COG3038	cytochrome b561
MTO68_RS09535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MTO68_RS09545	COG0527	aspartate kinase activity
MTO68_RS09565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MTO68_RS09590	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MTO68_RS09595	COG1522	sequence-specific DNA binding
MTO68_RS09600	COG1335	isochorismatase
MTO68_RS09615	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MTO68_RS09635	COG0667	Aldo Keto reductase
MTO68_RS09645	COG1765	OsmC-like protein
MTO68_RS09655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MTO68_RS09660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MTO68_RS09670	COG1045	serine acetyltransferase
MTO68_RS09680	COG0542	response to heat
MTO68_RS09710	COG0540	Belongs to the ATCase OTCase family
MTO68_RS09740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTO68_RS09750	COG0583	DNA-binding transcription factor activity
MTO68_RS09760	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MTO68_RS09785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MTO68_RS09790	COG0583	DNA-binding transcription factor activity
MTO68_RS09830	COG1309	transcriptional regulator
MTO68_RS09845	COG0693	protein deglycase activity
MTO68_RS09855	COG0582	viral genome integration into host DNA
MTO68_RS09860	COG2826	transposase and inactivated derivatives, IS30 family
MTO68_RS09900	COG2887	Belongs to the helicase family. UvrD subfamily
MTO68_RS10030	COG5410	chromosome segregation
MTO68_RS10165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MTO68_RS10180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MTO68_RS10220	COG0204	Acyl-transferase
MTO68_RS10235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MTO68_RS10245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MTO68_RS10255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MTO68_RS10275	COG0477	Major facilitator Superfamily
MTO68_RS10280	COG0729	surface antigen
MTO68_RS10290	COG0318	PFAM AMP-dependent synthetase and ligase
MTO68_RS10305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MTO68_RS10310	COG4783	chaperone-mediated protein folding
MTO68_RS10325	COG1610	YqeY-like protein
MTO68_RS10355	COG0436	Aminotransferase
MTO68_RS10360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MTO68_RS10365	COG0386	Belongs to the glutathione peroxidase family
MTO68_RS10370	COG1917	Cupin 2, conserved barrel domain protein
MTO68_RS10370	COG2207	Transcriptional regulator
MTO68_RS10400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MTO68_RS10420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MTO68_RS10445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MTO68_RS10450	COG0012	GTP binding
MTO68_RS10455	COG2011	ABC-type metal ion transport system permease component
MTO68_RS10460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MTO68_RS10465	COG1464	Belongs to the NlpA lipoprotein family
MTO68_RS10470	COG1464	Belongs to the NlpA lipoprotein family
MTO68_RS10530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MTO68_RS10540	COG0786	glutamate:sodium symporter activity
MTO68_RS10555	COG2707	UPF0756 membrane protein
MTO68_RS10560	COG1959	2 iron, 2 sulfur cluster binding
MTO68_RS10565	COG0492	ferredoxin-NADP+ reductase activity
MTO68_RS10570	COG1187	pseudouridine synthase activity
MTO68_RS10595	COG0802	atpase or kinase
MTO68_RS10610	COG1923	regulation of RNA biosynthetic process
MTO68_RS10615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MTO68_RS10625	COG3178	'Phosphotransferase
MTO68_RS10630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MTO68_RS10640	COG1192	Involved in chromosome partitioning
MTO68_RS10645	COG1475	DNA binding
MTO68_RS10650	COG0811	peptide transport
MTO68_RS10660	COG1132	(ABC) transporter
MTO68_RS10665	COG1663	tetraacyldisaccharide 4'-kinase activity
MTO68_RS10685	COG0084	hydrolase, TatD family'
MTO68_RS10710	COG3156	type II secretion system protein K
MTO68_RS10720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MTO68_RS10730	COG0590	tRNA wobble adenosine to inosine editing
MTO68_RS10740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MTO68_RS10770	COG3121	Chaperone
MTO68_RS10775	COG3539	Fimbrial protein
MTO68_RS10805	COG0284	orotidine-5'-phosphate decarboxylase activity
MTO68_RS10810	COG2431	L-lysine efflux transmembrane transporter activity
MTO68_RS10825	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MTO68_RS10830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MTO68_RS10835	COG0569	domain protein
MTO68_RS10850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MTO68_RS10855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MTO68_RS10905	COG3706	GGDEF domain
MTO68_RS10920	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MTO68_RS10925	COG0542	response to heat
MTO68_RS10930	COG0657	acetylesterase activity
MTO68_RS10930	COG2755	lipolytic protein G-D-S-L family
MTO68_RS10955	COG0583	DNA-binding transcription factor activity
MTO68_RS10960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MTO68_RS10970	COG0583	DNA-binding transcription factor activity
MTO68_RS10975	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS10980	COG2814	Major facilitator Superfamily
MTO68_RS10985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTO68_RS11015	COG0372	Belongs to the citrate synthase family
MTO68_RS11030	COG0069	glutamate synthase activity
MTO68_RS11050	COG2850	peptidyl-arginine hydroxylation
MTO68_RS11060	COG3609	addiction module antidote protein, CC2985 family
MTO68_RS11070	COG0424	maF-like protein
MTO68_RS11080	COG0126	phosphoglycerate kinase activity
MTO68_RS11110	COG3196	Protein conserved in bacteria
MTO68_RS11150	COG0702	epimerase
MTO68_RS11155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MTO68_RS11180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MTO68_RS11210	COG0316	Belongs to the HesB IscA family
MTO68_RS11215	COG0822	iron-sulfur transferase activity
MTO68_RS11225	COG1959	2 iron, 2 sulfur cluster binding
MTO68_RS11240	COG0776	regulation of translation
MTO68_RS11250	COG2207	Transcriptional regulator
MTO68_RS11255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTO68_RS11285	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MTO68_RS11315	COG1335	isochorismatase
MTO68_RS11345	COG1271	oxidase subunit
MTO68_RS11350	COG1294	oxidase, subunit
MTO68_RS11360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MTO68_RS11380	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MTO68_RS11390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MTO68_RS11415	COG0583	DNA-binding transcription factor activity
MTO68_RS11480	COG2814	Major facilitator Superfamily
MTO68_RS11490	COG0583	DNA-binding transcription factor activity
MTO68_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS11510	COG0697	spore germination
MTO68_RS11515	COG0436	Aminotransferase
MTO68_RS11525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MTO68_RS11545	COG0488	(ABC) transporter
MTO68_RS11555	COG0596	Alpha beta hydrolase
MTO68_RS11560	COG3135	benzoate transporter
MTO68_RS11585	COG2814	Major facilitator Superfamily
MTO68_RS11590	COG1346	cytolysis
MTO68_RS11595	COG1380	Effector of murein hydrolase LrgA
MTO68_RS11600	COG0583	DNA-binding transcription factor activity
MTO68_RS11700	COG4628	conserved protein (DUF2132)
MTO68_RS11710	COG1309	transcriptional regulator
MTO68_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS11735	COG0583	DNA-binding transcription factor activity
MTO68_RS11745	COG0626	cystathionine gamma-synthase activity
MTO68_RS11760	COG2826	transposase and inactivated derivatives, IS30 family
MTO68_RS11790	COG0183	Belongs to the thiolase family
MTO68_RS11800	COG1773	rubredoxin
MTO68_RS11810	COG1522	sequence-specific DNA binding
MTO68_RS11815	COG0583	DNA-binding transcription factor activity
MTO68_RS11820	COG2814	Major facilitator Superfamily
MTO68_RS11835	COG4774	siderophore transport
MTO68_RS11850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTO68_RS11865	COG1846	Transcriptional regulator
MTO68_RS11870	COG1309	transcriptional regulator
MTO68_RS11895	COG1024	Enoyl-CoA hydratase
MTO68_RS11900	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS11905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTO68_RS11920	COG0583	DNA-binding transcription factor activity
MTO68_RS11925	COG1944	ATP diphosphatase activity
MTO68_RS11940	COG2304	oxidoreductase activity
MTO68_RS11980	COG1358	cellular component organization or biogenesis
MTO68_RS12015	COG4245	von Willebrand factor, type A
MTO68_RS12020	COG0697	spore germination
MTO68_RS12035	COG2072	flavoprotein involved in K transport
MTO68_RS12060	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS12070	COG0583	DNA-binding transcription factor activity
MTO68_RS12075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTO68_RS12080	COG4266	Belongs to the allantoicase family
MTO68_RS12085	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MTO68_RS12095	COG2351	hydroxyisourate hydrolase activity
MTO68_RS12130	COG0804	urea catabolic process
MTO68_RS12160	COG0830	nickel cation binding
MTO68_RS12170	COG0589	response to stress
MTO68_RS12220	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS12225	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS12245	COG0509	glycine decarboxylation via glycine cleavage system
MTO68_RS12250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MTO68_RS12285	COG0640	Transcriptional regulator
MTO68_RS12305	COG3122	Protein conserved in bacteria
MTO68_RS12320	COG0588	phosphoglycerate mutase activity
MTO68_RS12325	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MTO68_RS12340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MTO68_RS12360	COG2814	Major facilitator Superfamily
MTO68_RS12390	COG2194	sulfuric ester hydrolase activity
MTO68_RS12395	COG2119	membrane
MTO68_RS12410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTO68_RS12430	COG1733	regulation of RNA biosynthetic process
MTO68_RS12435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MTO68_RS12440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MTO68_RS12445	COG2267	carboxylic ester hydrolase activity
MTO68_RS12450	COG0671	phosphoesterase, PA-phosphatase related
MTO68_RS12450	COG2453	phosphatase
MTO68_RS12465	COG4589	Belongs to the CDS family
MTO68_RS12480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MTO68_RS12485	COG2937	Belongs to the GPAT DAPAT family
MTO68_RS12490	COG2226	methyltransferase
MTO68_RS12490	COG0596	Alpha beta hydrolase
MTO68_RS12490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTO68_RS12495	COG1309	transcriptional regulator
MTO68_RS12525	COG0667	Aldo Keto reductase
MTO68_RS12550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MTO68_RS12575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTO68_RS12580	COG0772	Belongs to the SEDS family
MTO68_RS12590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MTO68_RS12600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MTO68_RS12615	COG1027	Aspartate ammonia-lyase
MTO68_RS12635	COG1902	pentaerythritol trinitrate reductase activity
MTO68_RS12635	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTO68_RS12645	COG2267	carboxylic ester hydrolase activity
MTO68_RS12655	COG2814	Major facilitator Superfamily
MTO68_RS12660	COG0583	DNA-binding transcription factor activity
MTO68_RS12670	COG4638	Rieske (2fe-2S)
MTO68_RS12675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MTO68_RS12680	COG0543	2 iron, 2 sulfur cluster binding
MTO68_RS12680	COG0633	Ferredoxin
MTO68_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS12690	COG3135	benzoate transporter
MTO68_RS12715	COG0477	Major facilitator Superfamily
MTO68_RS12735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MTO68_RS12745	COG1027	Aspartate ammonia-lyase
MTO68_RS12750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTO68_RS12760	COG0506	proline dehydrogenase activity
MTO68_RS12760	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MTO68_RS12760	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MTO68_RS12820	COG1570	exodeoxyribonuclease VII activity
MTO68_RS12830	COG0308	aminopeptidase N
MTO68_RS12860	COG1846	Transcriptional regulator
MTO68_RS12890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MTO68_RS12900	COG0511	ligase activity, forming carbon-carbon bonds
MTO68_RS12905	COG0439	Biotin carboxylase
MTO68_RS12915	COG3706	GGDEF domain
MTO68_RS12925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MTO68_RS12945	COG0730	response to heat
MTO68_RS12950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MTO68_RS12980	COG1011	Hydrolase
MTO68_RS12985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MTO68_RS12990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MTO68_RS12995	COG4221	oxidoreductase activity
MTO68_RS13000	COG0318	PFAM AMP-dependent synthetase and ligase
MTO68_RS13005	COG2137	regulation of response to DNA damage stimulus
MTO68_RS13020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MTO68_RS13030	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MTO68_RS13040	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MTO68_RS13055	COG0575	Belongs to the CDS family
MTO68_RS13060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MTO68_RS13065	COG0233	cytoplasmic translational termination
MTO68_RS13080	COG3852	Histidine kinase
MTO68_RS13085	COG2204	response regulator
MTO68_RS13095	COG3753	Protein conserved in bacteria
MTO68_RS13110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MTO68_RS13145	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
MTO68_RS13150	COG1132	(ABC) transporter
MTO68_RS13175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTO68_RS13190	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTO68_RS13205	COG1294	oxidase, subunit
MTO68_RS13210	COG4890	Cyd operon protein YbgT
MTO68_RS13275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MTO68_RS13290	COG0583	DNA-binding transcription factor activity
MTO68_RS13295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MTO68_RS13305	COG3135	benzoate transporter
MTO68_RS13310	COG0024	Methionine aminopeptidase
MTO68_RS13335	COG1253	flavin adenine dinucleotide binding
MTO68_RS13355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MTO68_RS13380	COG0552	protein localization to endoplasmic reticulum
MTO68_RS13385	COG0612	Peptidase, M16
MTO68_RS13415	COG0517	IMP dehydrogenase activity
MTO68_RS13415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MTO68_RS13420	COG0133	tryptophan synthase activity
MTO68_RS13430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTO68_RS13450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MTO68_RS13480	COG0537	adenosine 5'-monophosphoramidase activity
MTO68_RS13545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MTO68_RS13550	COG1454	alcohol dehydrogenase
MTO68_RS13565	COG0824	Thioesterase
MTO68_RS13575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MTO68_RS13620	COG0183	Belongs to the thiolase family
MTO68_RS13630	COG1454	alcohol dehydrogenase
MTO68_RS13645	COG3284	Transcriptional regulator
MTO68_RS13665	COG0583	DNA-binding transcription factor activity
MTO68_RS13690	COG1309	transcriptional regulator
MTO68_RS13695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MTO68_RS13695	COG0519	Catalyzes the synthesis of GMP from XMP
MTO68_RS13700	COG3042	response to heat
MTO68_RS13735	COG4978	Transcriptional regulator
MTO68_RS13735	COG0789	Transcriptional regulator
MTO68_RS13940	COG0305	Participates in initiation and elongation during chromosome replication
MTO68_RS14005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MTO68_RS14010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MTO68_RS14025	COG1280	lysine exporter protein (LysE YggA)
MTO68_RS14050	COG1254	Belongs to the acylphosphatase family
MTO68_RS14055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MTO68_RS14055	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MTO68_RS14080	COG1286	toxin biosynthetic process
MTO68_RS14110	COG0778	Nitroreductase
MTO68_RS14120	COG0513	Belongs to the DEAD box helicase family
MTO68_RS14125	COG1278	Cold shock
MTO68_RS14140	COG2363	Small membrane protein
MTO68_RS14170	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MTO68_RS14175	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTO68_RS14180	COG0625	glutathione transferase activity
MTO68_RS14185	COG0659	secondary active sulfate transmembrane transporter activity
MTO68_RS14195	COG4585	Histidine kinase
MTO68_RS14205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTO68_RS14210	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS14230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTO68_RS14235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTO68_RS14240	COG3781	membrane
MTO68_RS14245	COG2890	protein-(glutamine-N5) methyltransferase activity
MTO68_RS14250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MTO68_RS14265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTO68_RS14270	COG4682	membrane
MTO68_RS14305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MTO68_RS14310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MTO68_RS14315	COG1845	cytochrome c oxidase, subunit III
MTO68_RS14320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MTO68_RS14345	COG0360	Binds together with S18 to 16S ribosomal RNA
MTO68_RS14350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MTO68_RS14360	COG0305	Participates in initiation and elongation during chromosome replication
MTO68_RS14370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MTO68_RS14385	COG1305	Transglutaminase-like
MTO68_RS14395	COG2308	Evidence 4 Homologs of previously reported genes of
MTO68_RS14440	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MTO68_RS14445	COG0138	bifunctional purine biosynthesis protein purh
MTO68_RS14450	COG0151	Belongs to the GarS family
MTO68_RS14460	COG1464	Belongs to the NlpA lipoprotein family
MTO68_RS14465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MTO68_RS14470	COG2011	ABC-type metal ion transport system permease component
MTO68_RS14580	COG3022	response to hydroperoxide
MTO68_RS14590	COG4650	regulator
MTO68_RS14595	COG1234	tRNA 3'-trailer cleavage
MTO68_RS14610	COG1690	Belongs to the RtcB family
MTO68_RS14625	COG0430	RNA-3'-phosphate cyclase activity
MTO68_RS14645	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MTO68_RS14655	COG0693	protein deglycase activity
MTO68_RS14665	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS14670	COG0616	signal peptide processing
MTO68_RS14675	COG1301	dicarboxylic acid transport
MTO68_RS14680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MTO68_RS14690	COG0573	inorganic phosphate transmembrane transporter activity
MTO68_RS14705	COG4122	O-methyltransferase activity
MTO68_RS14745	COG1137	ATPase activity
MTO68_RS14750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MTO68_RS14760	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MTO68_RS14765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MTO68_RS14765	COG0517	IMP dehydrogenase activity
MTO68_RS14810	COG1671	Belongs to the UPF0178 family
MTO68_RS14820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MTO68_RS14845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTO68_RS14860	COG1301	dicarboxylic acid transport
MTO68_RS14870	COG0463	Glycosyl transferase, family 2
MTO68_RS14895	COG0047	phosphoribosylformylglycinamidine synthase activity
MTO68_RS14895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MTO68_RS14920	COG2255	four-way junction helicase activity
MTO68_RS14925	COG4771	TonB-dependent receptor
MTO68_RS14930	COG2031	fatty acid transporter
MTO68_RS14955	COG0824	Thioesterase
MTO68_RS14980	COG0823	Involved in the tonB-independent uptake of proteins
MTO68_RS15005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTO68_RS15025	COG0174	glutamine synthetase
MTO68_RS15070	COG0582	viral genome integration into host DNA
MTO68_RS15125	COG0582	viral genome integration into host DNA
MTO68_RS15135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MTO68_RS15320	COG1783	phage Terminase large subunit
MTO68_RS15325	COG3728	DNA packaging
MTO68_RS15405	COG0305	Participates in initiation and elongation during chromosome replication
MTO68_RS15430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MTO68_RS15450	COG3723	Recombinational DNA repair protein, rece pathway
MTO68_RS15485	COG0512	Glutamine amidotransferase of anthranilate synthase
MTO68_RS15490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MTO68_RS15505	COG0302	gtp cyclohydrolase
MTO68_RS15525	COG4302	ethanolamine ammonia-lyase activity
MTO68_RS15530	COG4303	Ethanolamine ammonia lyase large subunit
MTO68_RS15535	COG0531	amino acid
MTO68_RS15555	COG3739	integral membrane protein
MTO68_RS15570	COG1741	Belongs to the pirin family
MTO68_RS15575	COG0235	Class ii aldolase
MTO68_RS15585	COG2233	PERMEase
MTO68_RS15590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTO68_RS15595	COG0251	oxidation-reduction process
MTO68_RS15600	COG1335	isochorismatase
MTO68_RS15605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTO68_RS15610	COG0596	Alpha beta hydrolase
MTO68_RS15650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTO68_RS15660	COG0864	Transcriptional regulator
MTO68_RS15670	COG0439	Biotin carboxylase
MTO68_RS15685	COG0583	DNA-binding transcription factor activity
MTO68_RS15690	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MTO68_RS15700	COG4774	siderophore transport
MTO68_RS15730	COG0583	DNA-binding transcription factor activity
MTO68_RS15745	COG0251	oxidation-reduction process
MTO68_RS15750	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS15760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MTO68_RS15785	COG1629	transport
MTO68_RS15880	COG1113	amino acid transport
MTO68_RS15885	COG1414	Transcriptional regulator
MTO68_RS15890	COG2610	gluconate transmembrane transporter activity
MTO68_RS15895	COG1454	alcohol dehydrogenase
MTO68_RS15915	COG3188	usher protein
MTO68_RS15965	COG2855	membrane
MTO68_RS15985	COG3246	L-lysine catabolic process to acetate
MTO68_RS15990	COG2175	clavaminate synthase activity
MTO68_RS16020	COG3210	domain, Protein
MTO68_RS16025	COG2831	hemolysin activation secretion protein
MTO68_RS16030	COG4251	negative regulation of phosphorylation
MTO68_RS16030	COG2203	Gaf domain
MTO68_RS16030	COG3706	GGDEF domain
MTO68_RS16030	COG5001	Diguanylate cyclase
MTO68_RS16035	COG0659	secondary active sulfate transmembrane transporter activity
MTO68_RS16040	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MTO68_RS16045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MTO68_RS16050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MTO68_RS16065	COG3842	ATPase activity
MTO68_RS16070	COG1840	ABC-type Fe3 transport system, periplasmic component
MTO68_RS16100	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTO68_RS16100	COG1902	pentaerythritol trinitrate reductase activity
MTO68_RS16110	COG0277	FAD linked oxidase domain protein
MTO68_RS16120	COG2186	Transcriptional regulator
MTO68_RS16130	COG0697	spore germination
MTO68_RS16135	COG0583	DNA-binding transcription factor activity
MTO68_RS16170	COG0477	Major facilitator Superfamily
MTO68_RS16185	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS16230	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MTO68_RS16240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MTO68_RS16250	COG0280	phosphate acetyltransferase
MTO68_RS16250	COG0281	malic enzyme
MTO68_RS16260	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MTO68_RS16275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MTO68_RS16290	COG2351	hydroxyisourate hydrolase activity
MTO68_RS16300	COG1686	Belongs to the peptidase S11 family
MTO68_RS16305	COG1252	NADH dehydrogenase
MTO68_RS16310	COG1047	Peptidyl-prolyl cis-trans
MTO68_RS16315	COG0415	Belongs to the DNA photolyase family
MTO68_RS16345	COG0667	Aldo Keto reductase
MTO68_RS16355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MTO68_RS16360	COG1381	Involved in DNA repair and RecF pathway recombination
MTO68_RS16370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MTO68_RS16375	COG0571	ribonuclease III activity
MTO68_RS16405	COG4221	oxidoreductase activity
MTO68_RS16410	COG0625	glutathione transferase activity
MTO68_RS16415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MTO68_RS16425	COG0505	Belongs to the CarA family
MTO68_RS16435	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MTO68_RS16450	COG2207	Transcriptional regulator
MTO68_RS16475	COG2207	Transcriptional regulator
MTO68_RS16500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MTO68_RS16505	COG4638	Rieske (2fe-2S)
MTO68_RS16515	COG2271	Major facilitator Superfamily
MTO68_RS16530	COG0277	FAD linked oxidase domain protein
MTO68_RS16540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTO68_RS16580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MTO68_RS16590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MTO68_RS16600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MTO68_RS16605	COG4208	sulfate ABC transporter
MTO68_RS16610	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MTO68_RS16615	COG0583	DNA-binding transcription factor activity
MTO68_RS16635	COG0602	queuosine metabolic process
MTO68_RS16640	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MTO68_RS16655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MTO68_RS16665	COG0583	DNA-binding transcription factor activity
MTO68_RS16670	COG0625	glutathione transferase activity
MTO68_RS16680	COG2353	YceI-like domain
MTO68_RS16685	COG1051	belongs to the nudix hydrolase family
MTO68_RS16685	COG1056	cytidyltransferase-related domain
MTO68_RS16690	COG1024	Enoyl-CoA hydratase
MTO68_RS16695	COG0778	Nitroreductase
MTO68_RS16700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MTO68_RS16700	COG3323	Protein of unknown function (DUF1653)
MTO68_RS16725	COG1280	lysine exporter protein (LysE YggA)
MTO68_RS16730	COG1522	sequence-specific DNA binding
MTO68_RS16755	COG2234	aminopeptidase activity
MTO68_RS16760	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MTO68_RS16765	COG3384	dioxygenase
MTO68_RS16780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MTO68_RS16785	COG2878	Part of a membrane complex involved in electron transport
MTO68_RS16790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MTO68_RS16820	COG0768	penicillin binding
MTO68_RS16825	COG0742	ribosomal rna small subunit methyltransferase
MTO68_RS16840	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS16845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MTO68_RS16855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MTO68_RS16875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MTO68_RS16880	COG1053	succinate dehydrogenase
MTO68_RS16885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MTO68_RS16890	COG2009	succinate dehydrogenase
MTO68_RS16920	COG2072	flavoprotein involved in K transport
MTO68_RS16925	COG0300	oxidoreductase activity
MTO68_RS16965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MTO68_RS16970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTO68_RS16975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MTO68_RS16995	COG0505	Belongs to the CarA family
MTO68_RS17000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MTO68_RS17010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MTO68_RS17015	COG0110	maltose O-acetyltransferase activity
MTO68_RS17020	COG1113	amino acid transport
MTO68_RS17030	COG0625	glutathione transferase activity
MTO68_RS17055	COG1024	Enoyl-CoA hydratase
MTO68_RS17080	COG2321	neutral zinc metallopeptidase
MTO68_RS17085	COG2354	Protein conserved in bacteria
MTO68_RS17115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MTO68_RS17120	COG1773	rubredoxin
MTO68_RS17125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTO68_RS17135	COG0583	DNA-binding transcription factor activity
MTO68_RS17160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MTO68_RS17165	COG4181	ATPase activity
MTO68_RS17185	COG2826	transposase and inactivated derivatives, IS30 family
MTO68_RS17210	COG1278	Cold shock
MTO68_RS17350	COG0305	Participates in initiation and elongation during chromosome replication
MTO68_RS17370	COG3620	sequence-specific DNA binding
MTO68_RS17430	COG0560	Phosphoserine phosphatase
MTO68_RS17440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MTO68_RS17455	COG0424	maF-like protein
MTO68_RS17460	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MTO68_RS17465	COG1792	Involved in formation and maintenance of cell shape
MTO68_RS17470	COG1077	Cell shape determining protein MreB Mrl
MTO68_RS17475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MTO68_RS17485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MTO68_RS17510	COG2318	DinB family
MTO68_RS17535	COG0583	DNA-binding transcription factor activity
MTO68_RS17570	COG0523	cobalamin synthesis protein
MTO68_RS17580	COG1469	GTP cyclohydrolase I activity
MTO68_RS17590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTO68_RS17595	COG0789	Transcriptional regulator
MTO68_RS17600	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTO68_RS17600	COG1902	pentaerythritol trinitrate reductase activity
MTO68_RS17615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTO68_RS17630	COG0747	negative chemotaxis
MTO68_RS17650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTO68_RS17655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTO68_RS17660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTO68_RS17665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTO68_RS17695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTO68_RS17715	COG1132	(ABC) transporter
MTO68_RS17720	COG1132	(ABC) transporter
MTO68_RS17740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTO68_RS17745	COG0601	transmembrane transport
MTO68_RS17770	COG4774	siderophore transport
MTO68_RS17775	COG4607	ABC-type enterochelin transport system periplasmic component
MTO68_RS17780	COG4604	ABC transporter, ATP-binding protein
MTO68_RS17785	COG4605	iron ion homeostasis
MTO68_RS17790	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTO68_RS17795	COG1132	(ABC) transporter
MTO68_RS17800	COG1132	(ABC) transporter
MTO68_RS17800	COG2375	cellular response to nickel ion
MTO68_RS17810	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS17815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTO68_RS17830	COG1113	amino acid transport
MTO68_RS17835	COG1063	alcohol dehydrogenase
MTO68_RS17845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MTO68_RS17850	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTO68_RS17855	COG0022	dehydrogenase e1 component
MTO68_RS17860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTO68_RS17865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MTO68_RS17880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTO68_RS17885	COG1309	transcriptional regulator
MTO68_RS17905	COG1309	transcriptional regulator
MTO68_RS17910	COG2814	Major facilitator Superfamily
MTO68_RS17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTO68_RS17935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTO68_RS17940	COG0235	Class ii aldolase
MTO68_RS17945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTO68_RS17955	COG0028	Belongs to the TPP enzyme family
MTO68_RS17970	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS17975	COG2267	carboxylic ester hydrolase activity
MTO68_RS17985	COG2271	Major facilitator Superfamily
MTO68_RS17990	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTO68_RS18000	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS18025	COG2771	luxR family
MTO68_RS18045	COG1733	regulation of RNA biosynthetic process
MTO68_RS18120	COG3209	COG3209 Rhs family protein
MTO68_RS18130	COG0789	Transcriptional regulator
MTO68_RS18140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTO68_RS18145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTO68_RS18170	COG1595	DNA-templated transcription, initiation
MTO68_RS18180	COG0583	DNA-binding transcription factor activity
MTO68_RS18185	COG2610	gluconate transmembrane transporter activity
MTO68_RS18195	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS18200	COG0583	DNA-binding transcription factor activity
MTO68_RS18240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MTO68_RS18240	COG3008	intermembrane lipid transfer
MTO68_RS18260	COG0477	Major facilitator Superfamily
MTO68_RS18275	COG2274	protein secretion by the type I secretion system
MTO68_RS18295	COG0583	DNA-binding transcription factor activity
MTO68_RS18315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MTO68_RS18330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTO68_RS18335	COG1414	Transcriptional regulator
MTO68_RS18340	COG2819	hydrolase of the alpha beta superfamily
MTO68_RS18365	COG2985	domain, Protein
MTO68_RS18385	COG3327	negative regulation of DNA-templated transcription, initiation
MTO68_RS18390	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MTO68_RS18395	COG0183	Belongs to the thiolase family
MTO68_RS18400	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTO68_RS18405	COG1024	Enoyl-CoA hydratase
MTO68_RS18410	COG1024	Enoyl-CoA hydratase
MTO68_RS18415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MTO68_RS18420	COG2151	metal-sulfur cluster biosynthetic enzyme
MTO68_RS18425	COG3396	Phenylacetate-CoA oxygenase
MTO68_RS18430	COG3460	Phenylacetate-CoA oxygenase
MTO68_RS18435	COG3396	Phenylacetate-CoA oxygenase
MTO68_RS18440	COG2030	dehydratase
MTO68_RS18440	COG1012	belongs to the aldehyde dehydrogenase family
MTO68_RS18445	COG0477	Major facilitator Superfamily
MTO68_RS18495	COG3177	Filamentation induced by cAMP protein fic
MTO68_RS18510	COG2271	Major facilitator Superfamily
MTO68_RS18550	COG1401	restriction endodeoxyribonuclease activity
MTO68_RS18550	COG1401	restriction endodeoxyribonuclease activity
MTO68_RS18560	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MTO68_RS18565	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MTO68_RS18575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MTO68_RS18580	COG0242	peptide deformylase activity
MTO68_RS18595	COG3706	GGDEF domain
MTO68_RS18610	COG1585	Membrane protein implicated in regulation of membrane protease activity
MTO68_RS18615	COG2268	Band 7 protein
MTO68_RS18630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MTO68_RS18635	COG0523	cobalamin synthesis protein
MTO68_RS18660	COG1280	lysine exporter protein (LysE YggA)
MTO68_RS18670	COG0531	amino acid
MTO68_RS18670	COG1674	ftsk spoiiie
MTO68_RS18675	COG0492	ferredoxin-NADP+ reductase activity
MTO68_RS18680	COG0500	methyltransferase
MTO68_RS18685	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MTO68_RS18725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MTO68_RS18735	COG0714	Associated with various cellular activities
MTO68_RS18745	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MTO68_RS18755	COG3831	ATPase activity
MTO68_RS18760	COG3831	ATPase activity
MTO68_RS18770	COG1981	membrane
MTO68_RS18785	COG1113	amino acid transport
MTO68_RS18815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MTO68_RS18815	COG0351	phosphomethylpyrimidine kinase
MTO68_RS18815	COG0352	thiamine-phosphate diphosphorylase activity
MTO68_RS18830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MTO68_RS18855	COG2132	Multicopper oxidase
MTO68_RS18865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MTO68_RS18875	COG4269	membrane
MTO68_RS18880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MTO68_RS18895	COG1968	undecaprenyl-diphosphatase activity
MTO68_RS18900	COG1214	PFAM Peptidase M22, glycoprotease
MTO68_RS18905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MTO68_RS18910	COG0494	nUDIX hydrolase
MTO68_RS18960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MTO68_RS18970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MTO68_RS18995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTO68_RS19000	COG0765	amino acid transport
MTO68_RS19005	COG0765	amino acid transport
MTO68_RS19010	COG1126	abc transporter atp-binding protein
MTO68_RS19035	COG4716	Myosin-crossreactive antigen
MTO68_RS19050	COG2226	methyltransferase
MTO68_RS19080	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MTO68_RS19085	COG2081	HI0933 family
MTO68_RS19100	COG0668	transmembrane transport
MTO68_RS19120	COG2814	Major facilitator Superfamily
MTO68_RS19125	COG1289	transmembrane transporter activity
MTO68_RS19190	COG2832	Protein of unknown function (DUF454)
MTO68_RS19215	COG0643	Histidine kinase
MTO68_RS19215	COG2198	Histidine kinase
MTO68_RS19215	COG0784	Response regulator, receiver
MTO68_RS19220	COG0840	transmembrane signaling receptor activity
MTO68_RS19245	COG0442	prolyl-tRNA aminoacylation
MTO68_RS19300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MTO68_RS19310	COG0489	protein tyrosine kinase activity
MTO68_RS19345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTO68_RS19345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTO68_RS19390	COG2199	diguanylate cyclase activity
MTO68_RS19420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MTO68_RS19425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MTO68_RS19440	COG0450	alkyl hydroperoxide reductase
MTO68_RS19445	COG1652	LysM domain
MTO68_RS19450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTO68_RS19470	COG1399	metal-binding, possibly nucleic acid-binding protein
MTO68_RS19475	COG3101	peptidyl-lysine hydroxylation
MTO68_RS19480	COG0009	L-threonylcarbamoyladenylate synthase
MTO68_RS19510	COG0285	dihydrofolate synthase activity
MTO68_RS19550	COG3152	Membrane
MTO68_RS19560	COG0183	Belongs to the thiolase family
MTO68_RS19570	COG2207	Transcriptional regulator
MTO68_RS19575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTO68_RS19590	COG0494	nUDIX hydrolase
MTO68_RS19605	COG3422	double-strand break repair
MTO68_RS19620	COG4106	trans-aconitate 2-methyltransferase activity
MTO68_RS19635	COG2267	carboxylic ester hydrolase activity
MTO68_RS19645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MTO68_RS19655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTO68_RS19665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MTO68_RS19675	COG1196	nuclear chromosome segregation
MTO68_RS19685	COG0730	response to heat
MTO68_RS19710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MTO68_RS19730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MTO68_RS19820	COG1272	protein, Hemolysin III
MTO68_RS19825	COG0477	Major facilitator Superfamily
MTO68_RS19830	COG0564	pseudouridine synthase activity
MTO68_RS19840	COG1024	Enoyl-CoA hydratase
MTO68_RS19845	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS19850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTO68_RS19855	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS19865	COG1309	transcriptional regulator
MTO68_RS19870	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS19875	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS19880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTO68_RS19930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MTO68_RS19935	COG1846	Transcriptional regulator
MTO68_RS19940	COG1764	response to oxidative stress
MTO68_RS19970	COG3384	dioxygenase
MTO68_RS19980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTO68_RS20010	COG4206	TonB-dependent receptor
MTO68_RS20015	COG2096	Adenosyltransferase
MTO68_RS20035	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MTO68_RS20050	COG2315	Protein conserved in bacteria
MTO68_RS20055	COG0745	RESPONSE REGULATOR receiver
MTO68_RS20060	COG2205	protein histidine kinase activity
MTO68_RS20070	COG3028	Belongs to the UPF0307 family
MTO68_RS20075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MTO68_RS20080	COG1660	Displays ATPase and GTPase activities
MTO68_RS20085	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MTO68_RS20095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MTO68_RS20100	COG0617	tRNA 3'-terminal CCA addition
MTO68_RS20105	COG1555	photosystem II stabilization
MTO68_RS20105	COG1596	polysaccharide export
MTO68_RS20110	COG3956	TIGRFAM MazG family protein
MTO68_RS20125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MTO68_RS20145	COG0784	Response regulator, receiver
MTO68_RS20145	COG2205	protein histidine kinase activity
MTO68_RS20145	COG5002	protein histidine kinase activity
MTO68_RS20155	COG2084	Dehydrogenase
MTO68_RS20160	COG3622	Belongs to the hyi family
MTO68_RS20170	COG0004	ammonium transporteR
MTO68_RS20205	COG1426	Protein conserved in bacteria
MTO68_RS20230	COG0671	phosphoesterase, PA-phosphatase related
MTO68_RS20255	COG0440	acetolactate synthase activity
MTO68_RS20260	COG0028	Belongs to the TPP enzyme family
MTO68_RS20285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTO68_RS20290	COG0577	efflux transmembrane transporter activity
MTO68_RS20290	COG1136	(ABC) transporter
MTO68_RS20295	COG1538	Outer membrane efflux protein
MTO68_RS20310	COG2826	transposase and inactivated derivatives, IS30 family
MTO68_RS20355	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MTO68_RS20360	COG1162	GTPase activity
MTO68_RS20370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MTO68_RS20405	COG3783	Cytochrome b(562)
MTO68_RS20410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MTO68_RS20415	COG2003	Belongs to the UPF0758 family
MTO68_RS20420	COG3781	membrane
MTO68_RS20455	COG1946	Acyl-CoA thioesterase
MTO68_RS20470	COG1295	ribonuclease BN
MTO68_RS20480	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTO68_RS20505	COG2814	Major facilitator Superfamily
MTO68_RS20515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTO68_RS20520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTO68_RS20525	COG1126	abc transporter atp-binding protein
MTO68_RS20530	COG0765	amino acid transport
MTO68_RS20535	COG0765	amino acid transport
MTO68_RS20580	COG0339	signal peptide processing
MTO68_RS20585	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MTO68_RS20630	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MTO68_RS20635	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS20640	COG2072	flavoprotein involved in K transport
MTO68_RS20645	COG0203	ribosomal protein L17
MTO68_RS20650	COG0202	RNA polymerase activity
MTO68_RS20655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MTO68_RS20690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MTO68_RS20705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MTO68_RS20725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MTO68_RS20755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MTO68_RS20770	COG0088	Forms part of the polypeptide exit tunnel
MTO68_RS20775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MTO68_RS20780	COG0051	transcription antitermination factor activity, RNA binding
MTO68_RS20790	COG0626	cystathionine gamma-synthase activity
MTO68_RS20795	COG0433	COG0433 Predicted ATPase
MTO68_RS20805	COG1959	2 iron, 2 sulfur cluster binding
MTO68_RS20820	COG1301	dicarboxylic acid transport
MTO68_RS20825	COG1946	Acyl-CoA thioesterase
MTO68_RS20830	COG2937	Belongs to the GPAT DAPAT family
MTO68_RS20850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MTO68_RS20855	COG1040	competence protein
MTO68_RS20860	COG0494	nUDIX hydrolase
MTO68_RS20870	COG0598	Magnesium transport protein CorA
MTO68_RS20885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MTO68_RS20890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MTO68_RS20895	COG1127	ABC transporter
MTO68_RS20900	COG0513	Belongs to the DEAD box helicase family
MTO68_RS20915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTO68_RS20925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MTO68_RS20930	COG0408	coproporphyrinogen oxidase activity
MTO68_RS20950	COG1960	acyl-CoA dehydrogenase activity
MTO68_RS20955	COG1073	alpha beta
MTO68_RS20970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MTO68_RS20980	COG0534	Mate efflux family protein
MTO68_RS20990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MTO68_RS20995	COG0254	rRNA binding
MTO68_RS21000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MTO68_RS21030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MTO68_RS21035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTO68_RS21050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MTO68_RS21060	COG0644	oxidoreductase
MTO68_RS21060	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MTO68_RS21080	COG0425	Belongs to the sulfur carrier protein TusA family
MTO68_RS21085	COG4535	Mg2 and Co2 transporter CorC
MTO68_RS21090	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MTO68_RS21095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTO68_RS21095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTO68_RS21120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MTO68_RS21175	COG0475	glutathione-regulated potassium exporter activity
MTO68_RS21175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MTO68_RS21180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MTO68_RS21190	COG0789	Transcriptional regulator
MTO68_RS21195	COG2841	Protein conserved in bacteria
MTO68_RS21200	COG0598	Magnesium transport protein CorA
MTO68_RS21205	COG1185	polyribonucleotide nucleotidyltransferase activity
MTO68_RS21215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MTO68_RS21220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MTO68_RS21225	COG1074	ATP-dependent DNA helicase activity
MTO68_RS21230	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MTO68_RS21250	COG2271	Major facilitator Superfamily
MTO68_RS21255	COG1335	isochorismatase
MTO68_RS21260	COG3473	Maleate cis-trans isomerase
MTO68_RS21265	COG0596	Alpha beta hydrolase
MTO68_RS21270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTO68_RS21275	COG2309	aminopeptidase activity
MTO68_RS21280	COG1846	Transcriptional regulator
MTO68_RS21310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MTO68_RS21325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MTO68_RS21345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MTO68_RS21345	COG2111	Na H antiporter
MTO68_RS21350	COG1006	Multisubunit Na H antiporter MnhC subunit
MTO68_RS21355	COG0651	ATP synthesis coupled electron transport
MTO68_RS21360	COG1863	multisubunit Na H antiporter MnhE subunit
MTO68_RS21365	COG2212	antiporter activity
MTO68_RS21370	COG1320	monovalent cation:proton antiporter activity
MTO68_RS21375	COG0307	riboflavin synthase, alpha
MTO68_RS21385	COG1733	regulation of RNA biosynthetic process
MTO68_RS21390	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTO68_RS21395	COG0493	'glutamate synthase
MTO68_RS21400	COG0070	glutamate synthase
MTO68_RS21400	COG0069	glutamate synthase activity
MTO68_RS21400	COG0067	glutamate synthase
MTO68_RS21450	COG2226	methyltransferase
MTO68_RS21455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTO68_RS21460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MTO68_RS21465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MTO68_RS21475	COG3116	cell division
MTO68_RS21490	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MTO68_RS21505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MTO68_RS21560	COG4221	oxidoreductase activity
MTO68_RS21585	COG3320	Male sterility
MTO68_RS21585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTO68_RS21590	COG0789	Transcriptional regulator
MTO68_RS21615	COG0427	acetyl-CoA hydrolase
MTO68_RS21660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MTO68_RS21690	COG0697	spore germination
MTO68_RS21705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MTO68_RS21720	COG0488	(ABC) transporter
MTO68_RS21740	COG0704	Plays a role in the regulation of phosphate uptake
MTO68_RS21765	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MTO68_RS21770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MTO68_RS21775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MTO68_RS21785	COG0772	Belongs to the SEDS family
MTO68_RS21790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MTO68_RS21795	COG0586	Pfam SNARE associated Golgi protein
MTO68_RS21810	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MTO68_RS21810	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MTO68_RS21820	COG0004	ammonium transporteR
MTO68_RS21825	COG0347	Belongs to the P(II) protein family
MTO68_RS21835	COG0606	chelatase, subunit chli
MTO68_RS21840	COG3153	acetyltransferase
MTO68_RS21865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MTO68_RS21880	COG0318	PFAM AMP-dependent synthetase and ligase
MTO68_RS21895	COG0477	Major facilitator Superfamily
MTO68_RS21905	COG2860	membrane
MTO68_RS21910	COG3012	SEC-C Motif Domain Protein
MTO68_RS21915	COG1253	flavin adenine dinucleotide binding
MTO68_RS21960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTO68_RS21970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTO68_RS21975	COG3162	membrane
MTO68_RS21980	COG2205	protein histidine kinase activity
MTO68_RS21980	COG0784	Response regulator, receiver
MTO68_RS22000	COG2133	pyrroloquinoline quinone binding
MTO68_RS22030	COG1309	transcriptional regulator
MTO68_RS22060	COG1652	LysM domain
MTO68_RS22065	COG0758	DNA mediated transformation
MTO68_RS22070	COG0009	L-threonylcarbamoyladenylate synthase
MTO68_RS22075	COG0697	spore germination
MTO68_RS22080	COG1309	transcriptional regulator
MTO68_RS22105	COG0386	Belongs to the glutathione peroxidase family
MTO68_RS22140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MTO68_RS22150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MTO68_RS22180	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MTO68_RS22190	COG1121	(ABC) transporter
MTO68_RS22195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MTO68_RS22210	COG2837	iron assimilation
MTO68_RS22260	COG0281	malic enzyme
MTO68_RS22290	COG0745	RESPONSE REGULATOR receiver
MTO68_RS22295	COG2205	protein histidine kinase activity
MTO68_RS22300	COG4452	Inner membrane protein CreD
MTO68_RS22325	COG2814	Major facilitator Superfamily
MTO68_RS22335	COG0431	NADPH-dependent FMN reductase
MTO68_RS22355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTO68_RS22365	COG0668	transmembrane transport
MTO68_RS22370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MTO68_RS22375	COG1519	Transferase
MTO68_RS22380	COG1902	pentaerythritol trinitrate reductase activity
MTO68_RS22400	COG0519	Catalyzes the synthesis of GMP from XMP
MTO68_RS22400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MTO68_RS22410	COG2259	Doxx family
MTO68_RS22415	COG0586	Pfam SNARE associated Golgi protein
MTO68_RS22425	COG1192	Involved in chromosome partitioning
MTO68_RS22435	COG0271	Belongs to the BolA IbaG family
MTO68_RS22475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTO68_RS22480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MTO68_RS22495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MTO68_RS22500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MTO68_RS22550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MTO68_RS22560	COG1596	polysaccharide export
MTO68_RS22585	COG0728	peptidoglycan biosynthetic process
MTO68_RS22590	COG3023	N-Acetylmuramoyl-L-alanine amidase
MTO68_RS22620	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MTO68_RS22660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MTO68_RS22665	COG0546	phosphoglycolate phosphatase activity
MTO68_RS22670	COG1028	Short-chain dehydrogenase reductase Sdr
MTO68_RS22695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MTO68_RS22695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MTO68_RS22700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTO68_RS22705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTO68_RS22710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTO68_RS22715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTO68_RS22720	COG1116	anion transmembrane transporter activity
MTO68_RS22725	COG1309	transcriptional regulator
MTO68_RS22875	COG0737	Belongs to the 5'-nucleotidase family
MTO68_RS22880	COG2175	clavaminate synthase activity
MTO68_RS22885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTO68_RS22890	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MTO68_RS22895	COG4521	taurine ABC transporter
MTO68_RS22925	COG0443	Heat shock 70 kDa protein
MTO68_RS22960	COG2951	lytic endotransglycosylase activity
MTO68_RS22965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MTO68_RS22985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MTO68_RS22995	COG2388	GCN5-related N-acetyl-transferase
MTO68_RS23000	COG2388	GCN5-related N-acetyl-transferase
MTO68_RS23005	COG2814	Major facilitator Superfamily
MTO68_RS23020	COG0861	Integral membrane protein TerC family
MTO68_RS23030	COG0402	S-adenosylhomocysteine deaminase activity
MTO68_RS23040	COG2261	transglycosylase associated protein
MTO68_RS23050	COG1230	cation diffusion facilitator family transporter
MTO68_RS23075	COG0706	membrane insertase activity
MTO68_RS23080	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MTO68_RS23085	COG0594	ribonuclease P activity