locus-tag	class	description
CDG62_RS00305	COG1192	Involved in chromosome partitioning
CDG62_RS00455	COG0488	(ABC) transporter
CDG62_RS00460	COG3173	Aminoglycoside phosphotransferase
CDG62_RS00465	COG3328	transposase activity
CDG62_RS00475	COG2801	Transposase and inactivated derivatives
CDG62_RS00565	COG4115	mRNA cleavage
CDG62_RS00575	COG0488	(ABC) transporter
CDG62_RS00585	COG2801	Transposase and inactivated derivatives
CDG62_RS00680	COG2801	Transposase and inactivated derivatives
CDG62_RS00710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG62_RS00715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDG62_RS00725	COG0542	response to heat
CDG62_RS00840	COG1373	ATPase (AAA superfamily
CDG62_RS00850	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS00880	COG1324	tolerance protein
CDG62_RS00885	COG0673	inositol 2-dehydrogenase activity
CDG62_RS00905	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS00970	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CDG62_RS01285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_RS01290	COG1230	cation diffusion facilitator family transporter
CDG62_RS01300	COG0640	Transcriptional regulator
CDG62_RS01310	COG0789	Transcriptional regulator
CDG62_RS01420	COG1192	Involved in chromosome partitioning
CDG62_RS01425	COG1475	DNA binding
CDG62_RS01600	COG2009	succinate dehydrogenase
CDG62_RS01620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDG62_RS01630	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDG62_RS01685	COG0625	glutathione transferase activity
CDG62_RS01690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_RS01715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_RS01760	COG3293	Transposase
CDG62_RS01785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG62_RS01845	COG1132	(ABC) transporter
CDG62_RS01930	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS01940	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS02105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDG62_RS02160	COG1525	nuclease
CDG62_RS02205	COG1917	Cupin 2, conserved barrel domain protein
CDG62_RS02205	COG4977	sequence-specific DNA binding
CDG62_RS02210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_RS02220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG62_RS02225	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_RS02240	COG0183	Belongs to the thiolase family
CDG62_RS02245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_RS02315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CDG62_RS02340	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CDG62_RS02345	COG3421	Type III restriction
CDG62_RS02385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDG62_RS02485	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDG62_RS02520	COG0789	Transcriptional regulator
CDG62_RS02595	COG0210	DNA helicase
CDG62_RS02615	COG0583	DNA-binding transcription factor activity
CDG62_RS02620	COG2814	Major facilitator Superfamily
CDG62_RS02650	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_RS02690	COG1538	Outer membrane efflux protein
CDG62_RS02695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_RS02705	COG0745	RESPONSE REGULATOR receiver
CDG62_RS02710	COG2205	protein histidine kinase activity
CDG62_RS02725	COG2801	Transposase and inactivated derivatives
CDG62_RS02730	COG3173	Aminoglycoside phosphotransferase
CDG62_RS02735	COG0488	(ABC) transporter
CDG62_RS02740	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG62_RS02745	COG3657	addiction module killer protein
CDG62_RS02860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG62_RS02880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG62_RS02885	COG0592	DNA-directed DNA polymerase activity
CDG62_RS02895	COG0187	DNA topoisomerase II activity
CDG62_RS02905	COG0488	(ABC) transporter
CDG62_RS02965	COG0657	acetylesterase activity
CDG62_RS02975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG62_RS03005	COG2814	Major facilitator Superfamily
CDG62_RS03015	COG0733	neurotransmitter:sodium symporter activity
CDG62_RS03060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDG62_RS03060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDG62_RS03075	COG0129	dihydroxy-acid dehydratase activity
CDG62_RS03085	COG4774	siderophore transport
CDG62_RS03095	COG0583	DNA-binding transcription factor activity
CDG62_RS03100	COG2233	PERMEase
CDG62_RS03110	COG1309	transcriptional regulator
CDG62_RS03130	COG0484	heat shock protein binding
CDG62_RS03140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDG62_RS03155	COG0436	Aminotransferase
CDG62_RS03160	COG1064	alcohol dehydrogenase
CDG62_RS03165	COG2818	Glycosylase
CDG62_RS03195	COG5487	UPF0391 membrane protein
CDG62_RS03200	COG2983	Belongs to the UPF0260 family
CDG62_RS03205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDG62_RS03210	COG1280	lysine exporter protein (LysE YggA)
CDG62_RS03215	COG1522	sequence-specific DNA binding
CDG62_RS03225	COG4160	amino acid transport
CDG62_RS03235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDG62_RS03255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG62_RS03260	COG1335	isochorismatase
CDG62_RS03265	COG0385	Bile acid
CDG62_RS03335	COG0534	Mate efflux family protein
CDG62_RS03340	COG0436	Aminotransferase
CDG62_RS03345	COG2733	membrane
CDG62_RS03360	COG2918	glutathione biosynthetic process
CDG62_RS03365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CDG62_RS03375	COG3150	esterase
CDG62_RS03460	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDG62_RS03475	COG1393	Belongs to the ArsC family
CDG62_RS03480	COG0708	Exodeoxyribonuclease III
CDG62_RS03490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG62_RS03505	COG1846	Transcriptional regulator
CDG62_RS03510	COG0386	Belongs to the glutathione peroxidase family
CDG62_RS03515	COG0189	ligase activity
CDG62_RS03525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG62_RS03535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDG62_RS03545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDG62_RS03575	COG2119	membrane
CDG62_RS03580	COG0426	domain, Protein
CDG62_RS03580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_RS03605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDG62_RS03630	COG1902	pentaerythritol trinitrate reductase activity
CDG62_RS03635	COG1519	Transferase
CDG62_RS03640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG62_RS03645	COG0668	transmembrane transport
CDG62_RS03650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG62_RS03660	COG0579	oxidoreductase
CDG62_RS03670	COG0307	riboflavin synthase, alpha
CDG62_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS03690	COG0431	NADPH-dependent FMN reductase
CDG62_RS03705	COG2205	protein histidine kinase activity
CDG62_RS03705	COG0784	Response regulator, receiver
CDG62_RS03710	COG3162	membrane
CDG62_RS03715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG62_RS03725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG62_RS03740	COG3706	GGDEF domain
CDG62_RS03760	COG0351	phosphomethylpyrimidine kinase
CDG62_RS03760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG62_RS03760	COG0352	thiamine-phosphate diphosphorylase activity
CDG62_RS03770	COG2814	Major facilitator Superfamily
CDG62_RS03775	COG0629	single-stranded DNA binding
CDG62_RS03785	COG0583	DNA-binding transcription factor activity
CDG62_RS03790	COG1301	dicarboxylic acid transport
CDG62_RS03805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDG62_RS03810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_RS03825	COG1335	isochorismatase
CDG62_RS03835	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG62_RS03875	COG0556	nucleotide-excision repair
CDG62_RS03880	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDG62_RS03905	COG0582	viral genome integration into host DNA
CDG62_RS03935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDG62_RS03960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDG62_RS03965	COG1278	Cold shock
CDG62_RS03980	COG0531	amino acid
CDG62_RS03985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG62_RS04015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG62_RS04050	COG0427	acetyl-CoA hydrolase
CDG62_RS04080	COG4221	oxidoreductase activity
CDG62_RS04090	COG0488	(ABC) transporter
CDG62_RS04110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG62_RS04125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG62_RS04145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDG62_RS04150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG62_RS04160	COG2226	methyltransferase
CDG62_RS04210	COG0067	glutamate synthase
CDG62_RS04210	COG0070	glutamate synthase
CDG62_RS04210	COG0069	glutamate synthase activity
CDG62_RS04215	COG0493	'glutamate synthase
CDG62_RS04225	COG1704	LemA family
CDG62_RS04230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CDG62_RS04245	COG3307	-O-antigen
CDG62_RS04270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG62_RS04275	COG1758	RNA polymerase activity
CDG62_RS04280	COG0194	GDP metabolic process
CDG62_RS04290	COG4969	Belongs to the N-Me-Phe pilin family
CDG62_RS04325	COG0228	four-way junction DNA binding
CDG62_RS04330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG62_RS04340	COG0335	large ribosomal subunit rRNA binding
CDG62_RS04355	COG5380	lipid catabolic process
CDG62_RS04360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG62_RS04375	COG5006	permease, DMT superfamily
CDG62_RS04380	COG5006	permease, DMT superfamily
CDG62_RS04385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG62_RS04390	COG0277	FAD linked oxidase domain protein
CDG62_RS04400	COG2197	response regulator
CDG62_RS04405	COG0477	Major facilitator Superfamily
CDG62_RS04415	COG2814	Major facilitator Superfamily
CDG62_RS04420	COG1289	transmembrane transporter activity
CDG62_RS04425	COG2032	superoxide dismutase activity
CDG62_RS04430	COG0628	permease
CDG62_RS04435	COG1192	Involved in chromosome partitioning
CDG62_RS04445	COG2226	methyltransferase
CDG62_RS04460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG62_RS04465	COG0254	rRNA binding
CDG62_RS04470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG62_RS04480	COG0534	Mate efflux family protein
CDG62_RS04490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG62_RS04515	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS04525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDG62_RS04535	COG0408	coproporphyrinogen oxidase activity
CDG62_RS04540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG62_RS04565	COG1127	ABC transporter
CDG62_RS04570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG62_RS04575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG62_RS04580	COG2854	intermembrane phospholipid transfer
CDG62_RS04590	COG0598	Magnesium transport protein CorA
CDG62_RS04605	COG1040	competence protein
CDG62_RS04610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDG62_RS04625	COG2937	Belongs to the GPAT DAPAT family
CDG62_RS04630	COG1946	Acyl-CoA thioesterase
CDG62_RS04635	COG1301	dicarboxylic acid transport
CDG62_RS04650	COG1959	2 iron, 2 sulfur cluster binding
CDG62_RS04665	COG0300	oxidoreductase activity
CDG62_RS04670	COG0433	COG0433 Predicted ATPase
CDG62_RS04690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDG62_RS04695	COG0088	Forms part of the polypeptide exit tunnel
CDG62_RS04710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG62_RS04760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG62_RS04765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDG62_RS04775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG62_RS04800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDG62_RS04815	COG0202	RNA polymerase activity
CDG62_RS04820	COG0203	ribosomal protein L17
CDG62_RS04825	COG2072	flavoprotein involved in K transport
CDG62_RS04835	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS04840	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDG62_RS04870	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CDG62_RS04875	COG0339	signal peptide processing
CDG62_RS04880	COG2720	vancomycin resistance protein
CDG62_RS04885	COG0557	exoribonuclease II activity
CDG62_RS04915	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG62_RS04930	COG1295	ribonuclease BN
CDG62_RS04970	COG4773	Receptor
CDG62_RS04980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDG62_RS04985	COG1702	phosphate starvation-inducible protein PhoH
CDG62_RS04990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDG62_RS04995	COG1196	nuclear chromosome segregation
CDG62_RS04995	COG0739	heme binding
CDG62_RS04995	COG0741	lytic transglycosylase activity
CDG62_RS05030	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDG62_RS05035	COG1183	phosphatidylcholine synthase activity
CDG62_RS05075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_RS05100	COG1607	acyl-coa hydrolase
CDG62_RS05115	COG1666	GTP binding
CDG62_RS05135	COG2350	Protein conserved in bacteria
CDG62_RS05145	COG0613	PHP domain protein
CDG62_RS05150	COG3781	membrane
CDG62_RS05160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDG62_RS05185	COG1162	GTPase activity
CDG62_RS05190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG62_RS05205	COG1538	Outer membrane efflux protein
CDG62_RS05210	COG1136	(ABC) transporter
CDG62_RS05210	COG0577	efflux transmembrane transporter activity
CDG62_RS05215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_RS05245	COG0028	Belongs to the TPP enzyme family
CDG62_RS05250	COG0440	acetolactate synthase activity
CDG62_RS05285	COG0438	transferase activity, transferring glycosyl groups
CDG62_RS05315	COG1426	Protein conserved in bacteria
CDG62_RS05335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG62_RS05360	COG1862	Preprotein translocase
CDG62_RS05370	COG1704	LemA family
CDG62_RS05380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDG62_RS05390	COG5002	protein histidine kinase activity
CDG62_RS05395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG62_RS05430	COG0438	transferase activity, transferring glycosyl groups
CDG62_RS05450	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDG62_RS05465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG62_RS05470	COG0463	Glycosyl transferase, family 2
CDG62_RS05495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG62_RS05525	COG3223	Belongs to the PsiE family
CDG62_RS05530	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS05535	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS05545	COG2205	protein histidine kinase activity
CDG62_RS05550	COG0745	RESPONSE REGULATOR receiver
CDG62_RS05555	COG1113	amino acid transport
CDG62_RS05560	COG2315	Protein conserved in bacteria
CDG62_RS05565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDG62_RS05585	COG2096	Adenosyltransferase
CDG62_RS05590	COG4206	TonB-dependent receptor
CDG62_RS05615	COG3083	sulfuric ester hydrolase activity
CDG62_RS05640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDG62_RS05645	COG0285	dihydrofolate synthase activity
CDG62_RS05665	COG0450	alkyl hydroperoxide reductase
CDG62_RS05685	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG62_RS05690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG62_RS05720	COG2199	diguanylate cyclase activity
CDG62_RS05790	COG2969	positive regulation of protein catabolic process
CDG62_RS05795	COG0625	glutathione transferase activity
CDG62_RS05805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG62_RS05810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDG62_RS05815	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDG62_RS05820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG62_RS05825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG62_RS05850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG62_RS05860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG62_RS05865	COG1408	metallophosphoesterase
CDG62_RS05875	COG0477	Major facilitator Superfamily
CDG62_RS05880	COG1272	protein, Hemolysin III
CDG62_RS05905	COG0183	Belongs to the thiolase family
CDG62_RS05910	COG2207	Transcriptional regulator
CDG62_RS05915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG62_RS05930	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_RS05950	COG0183	Belongs to the thiolase family
CDG62_RS05965	COG0833	amino acid
CDG62_RS05970	COG2813	Specifically methylates the guanine in position
CDG62_RS05975	COG2233	PERMEase
CDG62_RS05980	COG1217	gtp-binding protein TYPA
CDG62_RS05985	COG1970	mechanosensitive ion channel activity
CDG62_RS05995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG62_RS06005	COG3659	wide pore channel activity
CDG62_RS06010	COG1902	pentaerythritol trinitrate reductase activity
CDG62_RS06045	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDG62_RS06095	COG0346	lactoylglutathione lyase activity
CDG62_RS06100	COG0564	pseudouridine synthase activity
CDG62_RS06120	COG3189	MarR family transcriptional regulator
CDG62_RS06125	COG2824	Alkylphosphonate utilization operon protein PhnA
CDG62_RS06135	COG3422	double-strand break repair
CDG62_RS06160	COG0488	(ABC) transporter
CDG62_RS06175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDG62_RS06195	COG0730	response to heat
CDG62_RS06205	COG1196	nuclear chromosome segregation
CDG62_RS06210	COG3115	cell septum assembly
CDG62_RS06215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG62_RS06220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG62_RS06225	COG4774	siderophore transport
CDG62_RS06240	COG2193	ferroxidase activity
CDG62_RS06245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG62_RS06250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG62_RS06250	COG0596	Alpha beta hydrolase
CDG62_RS06250	COG2226	methyltransferase
CDG62_RS06265	COG4106	trans-aconitate 2-methyltransferase activity
CDG62_RS06295	COG4206	TonB-dependent receptor
CDG62_RS06335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG62_RS06340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG62_RS06350	COG0009	L-threonylcarbamoyladenylate synthase
CDG62_RS06355	COG3101	peptidyl-lysine hydroxylation
CDG62_RS06360	COG1399	metal-binding, possibly nucleic acid-binding protein
CDG62_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS06385	COG1652	LysM domain
CDG62_RS06390	COG1802	Transcriptional regulator
CDG62_RS06420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG62_RS06430	COG0745	RESPONSE REGULATOR receiver
CDG62_RS06435	COG2205	protein histidine kinase activity
CDG62_RS06445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG62_RS06465	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDG62_RS06480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG62_RS06490	COG0713	ATP synthesis coupled electron transport
CDG62_RS06495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG62_RS06500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG62_RS06515	COG1278	Cold shock
CDG62_RS06520	COG1278	Cold shock
CDG62_RS06525	COG0583	DNA-binding transcription factor activity
CDG62_RS06550	COG0525	valine-tRNA ligase activity
CDG62_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS06570	COG0393	Putative heavy-metal-binding
CDG62_RS06575	COG0393	Putative heavy-metal-binding
CDG62_RS06580	COG1538	Outer membrane efflux protein
CDG62_RS06590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_RS06595	COG0671	phosphoesterase, PA-phosphatase related
CDG62_RS06615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDG62_RS06630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDG62_RS06640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDG62_RS06645	COG1648	precorrin-2 dehydrogenase activity
CDG62_RS06645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG62_RS06650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG62_RS06660	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS06670	COG0531	amino acid
CDG62_RS06685	COG0321	lipoyl(octanoyl) transferase activity
CDG62_RS06720	COG0586	Pfam SNARE associated Golgi protein
CDG62_RS06745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG62_RS06775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDG62_RS06805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDG62_RS06820	COG0358	DNA primase activity
CDG62_RS06830	COG0564	pseudouridine synthase activity
CDG62_RS06855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG62_RS06880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG62_RS06880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG62_RS06895	COG0300	oxidoreductase activity
CDG62_RS06900	COG2072	flavoprotein involved in K transport
CDG62_RS06910	COG2009	succinate dehydrogenase
CDG62_RS06915	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDG62_RS06920	COG1053	succinate dehydrogenase
CDG62_RS06925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG62_RS06940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_RS06950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDG62_RS06960	COG2268	Band 7 protein
CDG62_RS06965	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG62_RS06975	COG2354	Protein conserved in bacteria
CDG62_RS06980	COG2321	neutral zinc metallopeptidase
CDG62_RS07025	COG0505	Belongs to the CarA family
CDG62_RS07050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG62_RS07055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG62_RS07095	COG2851	Citrate transporter
CDG62_RS07100	COG1253	flavin adenine dinucleotide binding
CDG62_RS07130	COG2239	Acts as a magnesium transporter
CDG62_RS07145	COG0501	Belongs to the peptidase M48B family
CDG62_RS07150	COG0739	heme binding
CDG62_RS07150	COG0741	lytic transglycosylase activity
CDG62_RS07150	COG1196	nuclear chromosome segregation
CDG62_RS07155	COG0037	tRNA processing
CDG62_RS07165	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CDG62_RS07170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG62_RS07200	COG1309	transcriptional regulator
CDG62_RS07215	COG1741	Belongs to the pirin family
CDG62_RS07235	COG3739	integral membrane protein
CDG62_RS07250	COG3706	GGDEF domain
CDG62_RS07260	COG0302	gtp cyclohydrolase
CDG62_RS07270	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS07275	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_RS07295	COG0134	indole-3-glycerol-phosphate synthase activity
CDG62_RS07300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG62_RS07305	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG62_RS07310	COG0174	glutamine synthetase
CDG62_RS07320	COG3161	chorismate lyase activity
CDG62_RS07325	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG62_RS07365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG62_RS07370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG62_RS07375	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG62_RS07380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG62_RS07395	COG1115	amino acid carrier protein
CDG62_RS07400	COG1113	amino acid transport
CDG62_RS07410	COG0019	diaminopimelate decarboxylase activity
CDG62_RS07420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDG62_RS07430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDG62_RS07435	COG1522	sequence-specific DNA binding
CDG62_RS07440	COG1280	lysine exporter protein (LysE YggA)
CDG62_RS07475	COG0842	Transport permease protein
CDG62_RS07480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_RS07495	COG2175	clavaminate synthase activity
CDG62_RS07515	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG62_RS07550	COG2951	lytic endotransglycosylase activity
CDG62_RS07565	COG0842	Transport permease protein
CDG62_RS07570	COG1131	(ABC) transporter
CDG62_RS07580	COG0303	'Molybdopterin
CDG62_RS07585	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG62_RS07585	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDG62_RS07595	COG0243	molybdopterin cofactor binding
CDG62_RS07600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDG62_RS07610	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDG62_RS07615	COG4149	molybdate abc transporter
CDG62_RS07630	COG2169	Transcriptional regulator
CDG62_RS07635	COG0235	Class ii aldolase
CDG62_RS07640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG62_RS07645	COG0697	spore germination
CDG62_RS07650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG62_RS07650	COG0475	glutathione-regulated potassium exporter activity
CDG62_RS07655	COG3706	GGDEF domain
CDG62_RS07695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG62_RS07720	COG3634	alkyl hydroperoxide reductase activity
CDG62_RS07725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG62_RS07730	COG0826	peptidase U32
CDG62_RS07735	COG0789	Transcriptional regulator
CDG62_RS07770	COG1720	tRNA m6t6A37 methyltransferase activity
CDG62_RS07805	COG0642	Histidine kinase
CDG62_RS07815	COG0494	nUDIX hydrolase
CDG62_RS07825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG62_RS07830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG62_RS07835	COG3139	Protein of unknown function (DUF1315)
CDG62_RS07850	COG1301	dicarboxylic acid transport
CDG62_RS07855	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS07860	COG0693	protein deglycase activity
CDG62_RS07870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDG62_RS07875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG62_RS07905	COG0415	Belongs to the DNA photolyase family
CDG62_RS07915	COG2252	PERMEase
CDG62_RS07920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG62_RS07930	COG3038	cytochrome b561
CDG62_RS07945	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG62_RS07965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDG62_RS07980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDG62_RS07985	COG1522	sequence-specific DNA binding
CDG62_RS07990	COG1522	sequence-specific DNA binding
CDG62_RS07995	COG1335	isochorismatase
CDG62_RS08010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG62_RS08025	COG0667	Aldo Keto reductase
CDG62_RS08035	COG1765	OsmC-like protein
CDG62_RS08060	COG0540	Belongs to the ATCase OTCase family
CDG62_RS08080	COG2031	fatty acid transporter
CDG62_RS08085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_RS08100	COG4770	biotin carboxylase activity
CDG62_RS08110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG62_RS08115	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS08120	COG1309	transcriptional regulator
CDG62_RS08125	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_RS08155	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG62_RS08165	COG0659	secondary active sulfate transmembrane transporter activity
CDG62_RS08170	COG0625	glutathione transferase activity
CDG62_RS08175	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG62_RS08200	COG2363	Small membrane protein
CDG62_RS08215	COG1278	Cold shock
CDG62_RS08220	COG0513	Belongs to the DEAD box helicase family
CDG62_RS08230	COG0778	Nitroreductase
CDG62_RS08285	COG4783	chaperone-mediated protein folding
CDG62_RS08290	COG1610	YqeY-like protein
CDG62_RS08305	COG1335	isochorismatase
CDG62_RS08320	COG2815	serine threonine protein kinase
CDG62_RS08320	COG0515	serine threonine protein kinase
CDG62_RS08360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG62_RS08370	COG1643	Atp-dependent helicase
CDG62_RS08390	COG1116	anion transmembrane transporter activity
CDG62_RS08390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_RS08400	COG2223	nitrite transmembrane transporter activity
CDG62_RS08405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_RS08410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_RS08415	COG0243	molybdopterin cofactor binding
CDG62_RS08425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG62_RS08460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDG62_RS08465	COG0406	alpha-ribazole phosphatase activity
CDG62_RS08475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG62_RS08475	COG0517	IMP dehydrogenase activity
CDG62_RS08480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDG62_RS08490	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDG62_RS08495	COG1137	ATPase activity
CDG62_RS08515	COG4122	O-methyltransferase activity
CDG62_RS08525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDG62_RS08565	COG2011	ABC-type metal ion transport system permease component
CDG62_RS08570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG62_RS08575	COG1464	Belongs to the NlpA lipoprotein family
CDG62_RS08580	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG62_RS08590	COG0151	Belongs to the GarS family
CDG62_RS08595	COG0138	bifunctional purine biosynthesis protein purh
CDG62_RS08600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDG62_RS08630	COG0445	tRNA wobble uridine modification
CDG62_RS08640	COG2308	Evidence 4 Homologs of previously reported genes of
CDG62_RS08650	COG1305	Transglutaminase-like
CDG62_RS08665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG62_RS08670	COG0305	Participates in initiation and elongation during chromosome replication
CDG62_RS08685	COG0360	Binds together with S18 to 16S ribosomal RNA
CDG62_RS08705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDG62_RS08710	COG1845	cytochrome c oxidase, subunit III
CDG62_RS08715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG62_RS08720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG62_RS08750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_RS08765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDG62_RS08770	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG62_RS08775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG62_RS08780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_RS08810	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS08815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG62_RS08830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDG62_RS08850	COG0477	Major facilitator Superfamily
CDG62_RS08855	COG0729	surface antigen
CDG62_RS08900	COG4773	Receptor
CDG62_RS08905	COG0786	glutamate:sodium symporter activity
CDG62_RS08915	COG1113	amino acid transport
CDG62_RS08945	COG0024	Methionine aminopeptidase
CDG62_RS08950	COG3328	transposase activity
CDG62_RS08955	COG0583	DNA-binding transcription factor activity
CDG62_RS08960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG62_RS08975	COG3852	Histidine kinase
CDG62_RS08995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG62_RS09000	COG0575	Belongs to the CDS family
CDG62_RS09015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG62_RS09035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_RS09050	COG2137	regulation of response to DNA damage stimulus
CDG62_RS09055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDG62_RS09060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDG62_RS09065	COG1011	Hydrolase
CDG62_RS09105	COG0702	epimerase
CDG62_RS09110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG62_RS09120	COG2267	carboxylic ester hydrolase activity
CDG62_RS09130	COG1902	pentaerythritol trinitrate reductase activity
CDG62_RS09130	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG62_RS09145	COG2814	Major facilitator Superfamily
CDG62_RS09155	COG0583	DNA-binding transcription factor activity
CDG62_RS09175	COG0148	phosphopyruvate hydratase activity
CDG62_RS09190	COG0772	Belongs to the SEDS family
CDG62_RS09205	COG0579	oxidoreductase
CDG62_RS09215	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_RS09220	COG1309	transcriptional regulator
CDG62_RS09225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG62_RS09240	COG4890	Cyd operon protein YbgT
CDG62_RS09245	COG1294	oxidase, subunit
CDG62_RS09260	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG62_RS09270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG62_RS09290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG62_RS09295	COG0569	domain protein
CDG62_RS09305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG62_RS09310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDG62_RS09320	COG3706	GGDEF domain
CDG62_RS09335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG62_RS09340	COG0542	response to heat
CDG62_RS09370	COG0372	Belongs to the citrate synthase family
CDG62_RS09380	COG2819	hydrolase of the alpha beta superfamily
CDG62_RS09385	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_RS09410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDG62_RS09410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDG62_RS09415	COG1254	Belongs to the acylphosphatase family
CDG62_RS09420	COG1047	Peptidyl-prolyl cis-trans
CDG62_RS09425	COG1252	NADH dehydrogenase
CDG62_RS09430	COG1686	Belongs to the peptidase S11 family
CDG62_RS09440	COG2351	hydroxyisourate hydrolase activity
CDG62_RS09605	COG5410	chromosome segregation
CDG62_RS09750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG62_RS09755	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS09775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG62_RS09800	COG0582	viral genome integration into host DNA
CDG62_RS09830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_RS09835	COG1823	symporter activity
CDG62_RS09845	COG0612	Peptidase, M16
CDG62_RS09880	COG0352	thiamine-phosphate diphosphorylase activity
CDG62_RS09905	COG1942	4-Oxalocrotonate Tautomerase
CDG62_RS09910	COG0583	DNA-binding transcription factor activity
CDG62_RS09945	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG62_RS09950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDG62_RS09960	COG0456	acetyltransferase
CDG62_RS09970	COG0519	Catalyzes the synthesis of GMP from XMP
CDG62_RS09970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG62_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS09990	COG4302	ethanolamine ammonia-lyase activity
CDG62_RS09995	COG4303	Ethanolamine ammonia lyase large subunit
CDG62_RS10000	COG0531	amino acid
CDG62_RS10020	COG1454	alcohol dehydrogenase
CDG62_RS10030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG62_RS10035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG62_RS10040	COG2814	Major facilitator Superfamily
CDG62_RS10045	COG2707	UPF0756 membrane protein
CDG62_RS10050	COG1187	pseudouridine synthase activity
CDG62_RS10070	COG0802	atpase or kinase
CDG62_RS10075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDG62_RS10085	COG1923	regulation of RNA biosynthetic process
CDG62_RS10090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG62_RS10105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDG62_RS10115	COG1192	Involved in chromosome partitioning
CDG62_RS10120	COG1475	DNA binding
CDG62_RS10125	COG0811	peptide transport
CDG62_RS10135	COG1132	(ABC) transporter
CDG62_RS10140	COG1663	tetraacyldisaccharide 4'-kinase activity
CDG62_RS10160	COG0084	hydrolase, TatD family'
CDG62_RS10195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDG62_RS10205	COG0590	tRNA wobble adenosine to inosine editing
CDG62_RS10225	COG0776	regulation of translation
CDG62_RS10245	COG2431	L-lysine efflux transmembrane transporter activity
CDG62_RS10260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDG62_RS10265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDG62_RS10285	COG1253	flavin adenine dinucleotide binding
CDG62_RS10310	COG0308	aminopeptidase N
CDG62_RS10320	COG0589	response to stress
CDG62_RS10335	COG2076	Multidrug Resistance protein
CDG62_RS10340	COG1309	transcriptional regulator
CDG62_RS10345	COG3135	benzoate transporter
CDG62_RS10355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG62_RS10360	COG0583	DNA-binding transcription factor activity
CDG62_RS10375	COG0183	Belongs to the thiolase family
CDG62_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS10400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDG62_RS10405	COG0824	Thioesterase
CDG62_RS10410	COG1454	alcohol dehydrogenase
CDG62_RS10415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDG62_RS10435	COG0069	glutamate synthase activity
CDG62_RS10440	COG2197	response regulator
CDG62_RS10445	COG4585	Histidine kinase
CDG62_RS10450	COG2850	peptidyl-arginine hydroxylation
CDG62_RS10455	COG0424	maF-like protein
CDG62_RS10465	COG0126	phosphoglycerate kinase activity
CDG62_RS10480	COG0697	spore germination
CDG62_RS10505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_RS10515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG62_RS10520	COG3781	membrane
CDG62_RS10535	COG3328	transposase activity
CDG62_RS10560	COG0506	proline dehydrogenase activity
CDG62_RS10560	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG62_RS10560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG62_RS10570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG62_RS10580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDG62_RS10610	COG0316	Belongs to the HesB IscA family
CDG62_RS10615	COG0822	iron-sulfur transferase activity
CDG62_RS10625	COG1959	2 iron, 2 sulfur cluster binding
CDG62_RS10640	COG0776	regulation of translation
CDG62_RS10645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG62_RS10670	COG0537	adenosine 5'-monophosphoramidase activity
CDG62_RS10715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG62_RS10720	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CDG62_RS10735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG62_RS10745	COG0133	tryptophan synthase activity
CDG62_RS10750	COG0517	IMP dehydrogenase activity
CDG62_RS10780	COG0612	Peptidase, M16
CDG62_RS10785	COG0552	protein localization to endoplasmic reticulum
CDG62_RS10835	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS10840	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS10890	COG2199	diguanylate cyclase activity
CDG62_RS10900	COG2814	Major facilitator Superfamily
CDG62_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS10925	COG0864	Transcriptional regulator
CDG62_RS10950	COG1116	anion transmembrane transporter activity
CDG62_RS10995	COG0596	Alpha beta hydrolase
CDG62_RS11010	COG2909	trisaccharide binding
CDG62_RS11030	COG2267	carboxylic ester hydrolase activity
CDG62_RS11060	COG0583	DNA-binding transcription factor activity
CDG62_RS11090	COG4774	siderophore transport
CDG62_RS11110	COG0789	Transcriptional regulator
CDG62_RS11115	COG1902	pentaerythritol trinitrate reductase activity
CDG62_RS11120	COG3268	Saccharopine dehydrogenase
CDG62_RS11170	COG2814	Major facilitator Superfamily
CDG62_RS11175	COG0583	DNA-binding transcription factor activity
CDG62_RS11180	COG4948	Mandelate Racemase Muconate Lactonizing
CDG62_RS11185	COG4829	muconolactone delta-isomerase
CDG62_RS11195	COG4638	Rieske (2fe-2S)
CDG62_RS11200	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CDG62_RS11205	COG0633	Ferredoxin
CDG62_RS11205	COG0543	2 iron, 2 sulfur cluster binding
CDG62_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS11215	COG3135	benzoate transporter
CDG62_RS11220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG62_RS11225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_RS11230	COG0183	Belongs to the thiolase family
CDG62_RS11235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG62_RS11245	COG0511	ligase activity, forming carbon-carbon bonds
CDG62_RS11265	COG0439	Biotin carboxylase
CDG62_RS11280	COG0583	DNA-binding transcription factor activity
CDG62_RS11285	COG0183	Belongs to the thiolase family
CDG62_RS11295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG62_RS11305	COG2233	PERMEase
CDG62_RS11310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_RS11315	COG0251	oxidation-reduction process
CDG62_RS11320	COG1335	isochorismatase
CDG62_RS11325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_RS11330	COG0596	Alpha beta hydrolase
CDG62_RS11335	COG0640	Transcriptional regulator
CDG62_RS11355	COG3122	Protein conserved in bacteria
CDG62_RS11360	COG0668	transmembrane transport
CDG62_RS11370	COG1132	(ABC) transporter
CDG62_RS11385	COG2814	Major facilitator Superfamily
CDG62_RS11395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG62_RS11400	COG3300	MHYT domain
CDG62_RS11400	COG5001	Diguanylate cyclase
CDG62_RS11415	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG62_RS11420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG62_RS11440	COG3123	guanosine phosphorylase activity
CDG62_RS11465	COG0583	DNA-binding transcription factor activity
CDG62_RS11495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG62_RS11500	COG1846	Transcriptional regulator
CDG62_RS11510	COG3038	cytochrome b561
CDG62_RS11515	COG1484	DNA-dependent DNA replication
CDG62_RS11520	COG4584	PFAM Integrase catalytic
CDG62_RS11555	COG4372	Transposase
CDG62_RS11575	COG3328	transposase activity
CDG62_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS11635	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CDG62_RS11660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG62_RS11665	COG0583	DNA-binding transcription factor activity
CDG62_RS11675	COG1346	cytolysis
CDG62_RS11690	COG2223	nitrite transmembrane transporter activity
CDG62_RS11720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG62_RS11725	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_RS11730	COG2207	Transcriptional regulator
CDG62_RS11735	COG1944	ATP diphosphatase activity
CDG62_RS11740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_RS11775	COG2801	Transposase and inactivated derivatives
CDG62_RS11790	COG0730	response to heat
CDG62_RS11795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG62_RS11835	COG0204	Acyl-transferase
CDG62_RS11845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CDG62_RS11875	COG1464	Belongs to the NlpA lipoprotein family
CDG62_RS11880	COG1464	Belongs to the NlpA lipoprotein family
CDG62_RS11885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG62_RS11890	COG2011	ABC-type metal ion transport system permease component
CDG62_RS11895	COG0012	GTP binding
CDG62_RS11920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDG62_RS11935	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDG62_RS11960	COG0386	Belongs to the glutathione peroxidase family
CDG62_RS11965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_RS11970	COG0436	Aminotransferase
CDG62_RS11990	COG3634	alkyl hydroperoxide reductase activity
CDG62_RS12015	COG2070	2-Nitropropane dioxygenase
CDG62_RS12035	COG0604	alcohol dehydrogenase
CDG62_RS12110	COG1309	transcriptional regulator
CDG62_RS12135	COG0842	Transport permease protein
CDG62_RS12140	COG0842	Transport permease protein
CDG62_RS12145	COG1131	(ABC) transporter
CDG62_RS12180	COG1538	Outer membrane efflux protein
CDG62_RS12190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_RS12195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_RS12205	COG3712	iron ion homeostasis
CDG62_RS12225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG62_RS12230	COG0697	spore germination
CDG62_RS12245	COG1538	Outer membrane efflux protein
CDG62_RS12250	COG0457	Tetratricopeptide repeat
CDG62_RS12250	COG0463	Glycosyl transferase, family 2
CDG62_RS12280	COG1126	abc transporter atp-binding protein
CDG62_RS12285	COG0765	amino acid transport
CDG62_RS12300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDG62_RS12305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_RS12310	COG1473	amidohydrolase
CDG62_RS12315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_RS12325	COG0625	glutathione transferase activity
CDG62_RS12360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG62_RS12395	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS12425	COG1324	tolerance protein
CDG62_RS12430	COG0673	inositol 2-dehydrogenase activity
CDG62_RS12450	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS12510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG62_RS12540	COG2801	Transposase and inactivated derivatives
CDG62_RS12565	COG0714	Associated with various cellular activities
CDG62_RS12570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDG62_RS12575	COG2879	small protein
CDG62_RS12580	COG1966	Carbon starvation protein
CDG62_RS12585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG62_RS12605	COG0254	rRNA binding
CDG62_RS12630	COG1067	ATP-dependent peptidase activity
CDG62_RS12635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG62_RS12640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG62_RS12645	COG0616	signal peptide processing
CDG62_RS12650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG62_RS12660	COG0573	inorganic phosphate transmembrane transporter activity
CDG62_RS12665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDG62_RS12675	COG0076	glutamate decarboxylase activity
CDG62_RS12680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG62_RS12690	COG4772	TonB-dependent receptor
CDG62_RS12695	COG0671	phosphoesterase, PA-phosphatase related
CDG62_RS12710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDG62_RS12720	COG1733	regulation of RNA biosynthetic process
CDG62_RS12725	COG0702	epimerase
CDG62_RS12755	COG0556	nucleotide-excision repair
CDG62_RS12770	COG2199	diguanylate cyclase activity
CDG62_RS12780	COG0436	Aminotransferase
CDG62_RS12820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDG62_RS12825	COG1381	Involved in DNA repair and RecF pathway recombination
CDG62_RS12835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG62_RS12840	COG0571	ribonuclease III activity
CDG62_RS12850	COG0681	Belongs to the peptidase S26 family
CDG62_RS12865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG62_RS12885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDG62_RS12895	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG62_RS12910	COG4208	sulfate ABC transporter
CDG62_RS12915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDG62_RS12920	COG0583	DNA-binding transcription factor activity
CDG62_RS12940	COG0602	queuosine metabolic process
CDG62_RS12945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDG62_RS12960	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG62_RS12970	COG0583	DNA-binding transcription factor activity
CDG62_RS12975	COG2353	YceI-like domain
CDG62_RS12980	COG1056	cytidyltransferase-related domain
CDG62_RS12980	COG1051	belongs to the nudix hydrolase family
CDG62_RS12985	COG1024	Enoyl-CoA hydratase
CDG62_RS12990	COG0778	Nitroreductase
CDG62_RS13000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG62_RS13000	COG3323	Protein of unknown function (DUF1653)
CDG62_RS13010	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG62_RS13010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG62_RS13025	COG2255	four-way junction helicase activity
CDG62_RS13030	COG1473	amidohydrolase
CDG62_RS13045	COG0824	Thioesterase
CDG62_RS13065	COG0823	Involved in the tonB-independent uptake of proteins
CDG62_RS13085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG62_RS13120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG62_RS13125	COG0628	permease
CDG62_RS13135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDG62_RS13155	COG0658	competence protein
CDG62_RS13155	COG2333	competence protein COMEC
CDG62_RS13160	COG1136	(ABC) transporter
CDG62_RS13165	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDG62_RS13180	COG1671	Belongs to the UPF0178 family
CDG62_RS13190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_RS13195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG62_RS13240	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG62_RS13245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDG62_RS13250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG62_RS13255	COG1716	ATPase activity
CDG62_RS13255	COG5001	Diguanylate cyclase
CDG62_RS13260	COG0281	malic enzyme
CDG62_RS13260	COG0280	phosphate acetyltransferase
CDG62_RS13285	COG1773	rubredoxin
CDG62_RS13290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_RS13335	COG1024	Enoyl-CoA hydratase
CDG62_RS13340	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS13345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG62_RS13360	COG0583	DNA-binding transcription factor activity
CDG62_RS13385	COG3328	transposase activity
CDG62_RS13400	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG62_RS13400	COG1902	pentaerythritol trinitrate reductase activity
CDG62_RS13405	COG0277	FAD linked oxidase domain protein
CDG62_RS13415	COG2186	Transcriptional regulator
CDG62_RS13430	COG3706	GGDEF domain
CDG62_RS13430	COG4251	negative regulation of phosphorylation
CDG62_RS13430	COG5001	Diguanylate cyclase
CDG62_RS13430	COG2203	Gaf domain
CDG62_RS13435	COG0418	dihydroorotase activity
CDG62_RS13440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG62_RS13450	COG0833	amino acid
CDG62_RS13460	COG0833	amino acid
CDG62_RS13505	COG4172	Belongs to the ABC transporter superfamily
CDG62_RS13510	COG4239	(ABC) transporter, permease
CDG62_RS13515	COG4174	ABC transporter (Permease)
CDG62_RS13520	COG4166	transmembrane transport
CDG62_RS13525	COG0741	lytic transglycosylase activity
CDG62_RS13525	COG1388	LysM domain
CDG62_RS13530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG62_RS13545	COG0657	acetylesterase activity
CDG62_RS13565	COG0583	DNA-binding transcription factor activity
CDG62_RS13570	COG1388	LysM domain
CDG62_RS13570	COG4942	peptidase
CDG62_RS13580	COG0582	viral genome integration into host DNA
CDG62_RS13610	COG0753	catalase activity
CDG62_RS13640	COG1686	Belongs to the peptidase S11 family
CDG62_RS13645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG62_RS13650	COG0583	DNA-binding transcription factor activity
CDG62_RS13655	COG1335	isochorismatase
CDG62_RS13670	COG2915	High frequency lysogenization protein hflD homolog
CDG62_RS13690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG62_RS13695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG62_RS13705	COG3706	GGDEF domain
CDG62_RS13710	COG0006	proline dipeptidase activity
CDG62_RS13745	COG1234	tRNA 3'-trailer cleavage
CDG62_RS13750	COG4221	oxidoreductase activity
CDG62_RS13755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG62_RS13760	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CDG62_RS13800	COG4399	Belongs to the UPF0754 family
CDG62_RS13815	COG4770	biotin carboxylase activity
CDG62_RS13835	COG1914	H( )-stimulated, divalent metal cation uptake system
CDG62_RS13845	COG2217	Heavy metal translocating P-type atpase
CDG62_RS13855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG62_RS13870	COG2234	aminopeptidase activity
CDG62_RS13880	COG3384	dioxygenase
CDG62_RS13890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG62_RS13895	COG2878	Part of a membrane complex involved in electron transport
CDG62_RS13900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDG62_RS13925	COG0768	penicillin binding
CDG62_RS13930	COG0742	ribosomal rna small subunit methyltransferase
CDG62_RS13955	COG3119	arylsulfatase activity
CDG62_RS13960	COG0641	radical SAM
CDG62_RS13995	COG1597	lipid kinase activity
CDG62_RS14010	COG0477	Major facilitator Superfamily
CDG62_RS14050	COG0604	alcohol dehydrogenase
CDG62_RS14050	COG3321	synthase
CDG62_RS14050	COG4221	oxidoreductase activity
CDG62_RS14050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG62_RS14065	COG1695	Transcriptional regulator
CDG62_RS14105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDG62_RS14110	COG1773	rubredoxin
CDG62_RS14115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_RS14125	COG0583	DNA-binding transcription factor activity
CDG62_RS14145	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CDG62_RS14150	COG4181	ATPase activity
CDG62_RS14175	COG4771	TonB-dependent receptor
CDG62_RS14195	COG0306	phosphate transporter
CDG62_RS14235	COG2223	nitrite transmembrane transporter activity
CDG62_RS14245	COG0242	peptide deformylase activity
CDG62_RS14250	COG0477	Major facilitator Superfamily
CDG62_RS14290	COG0456	acetyltransferase
CDG62_RS14295	COG2203	Gaf domain
CDG62_RS14295	COG2199	diguanylate cyclase activity
CDG62_RS14305	COG4681	YaeQ
CDG62_RS14310	COG0523	cobalamin synthesis protein
CDG62_RS14325	COG1607	acyl-coa hydrolase
CDG62_RS14330	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG62_RS14340	COG1115	amino acid carrier protein
CDG62_RS14345	COG0786	glutamate:sodium symporter activity
CDG62_RS14365	COG2814	Major facilitator Superfamily
CDG62_RS14370	COG1289	transmembrane transporter activity
CDG62_RS14380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDG62_RS14450	COG2832	Protein of unknown function (DUF454)
CDG62_RS14465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG62_RS14475	COG0643	Histidine kinase
CDG62_RS14475	COG0784	Response regulator, receiver
CDG62_RS14475	COG2198	Histidine kinase
CDG62_RS14480	COG0840	transmembrane signaling receptor activity
CDG62_RS14550	COG2358	TRAP transporter, solute receptor (TAXI family
CDG62_RS14565	COG0489	protein tyrosine kinase activity
CDG62_RS14585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG62_RS14585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG62_RS14610	COG4716	Myosin-crossreactive antigen
CDG62_RS14640	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CDG62_RS14645	COG2081	HI0933 family
CDG62_RS14655	COG0668	transmembrane transport
CDG62_RS14675	COG0765	amino acid transport
CDG62_RS14680	COG0765	amino acid transport
CDG62_RS14685	COG1126	abc transporter atp-binding protein
CDG62_RS14695	COG0004	ammonium transporteR
CDG62_RS14710	COG0642	Histidine kinase
CDG62_RS14715	COG0745	RESPONSE REGULATOR receiver
CDG62_RS14740	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG62_RS14755	COG0142	geranyltranstransferase activity
CDG62_RS14760	COG2828	Protein conserved in bacteria
CDG62_RS14765	COG1113	amino acid transport
CDG62_RS14780	COG1113	amino acid transport
CDG62_RS14800	COG0625	glutathione transferase activity
CDG62_RS14815	COG0431	NADPH-dependent FMN reductase
CDG62_RS14820	COG0798	PFAM Bile acid sodium symporter
CDG62_RS14830	COG0640	Transcriptional regulator
CDG62_RS14885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG62_RS14895	COG0424	maF-like protein
CDG62_RS14900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CDG62_RS14905	COG1792	Involved in formation and maintenance of cell shape
CDG62_RS14910	COG1077	Cell shape determining protein MreB Mrl
CDG62_RS14915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG62_RS14925	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG62_RS14970	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDG62_RS14985	COG1595	DNA-templated transcription, initiation
CDG62_RS15050	COG1785	Belongs to the alkaline phosphatase family
CDG62_RS15055	COG1785	Belongs to the alkaline phosphatase family
CDG62_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS15065	COG2610	gluconate transmembrane transporter activity
CDG62_RS15070	COG0583	DNA-binding transcription factor activity
CDG62_RS15080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_RS15090	COG4772	TonB-dependent receptor
CDG62_RS15095	COG4993	Dehydrogenase
CDG62_RS15100	COG3659	wide pore channel activity
CDG62_RS15105	COG3420	alginic acid biosynthetic process
CDG62_RS15110	COG0710	3-dehydroquinate dehydratase activity
CDG62_RS15115	COG3485	protocatechuate 3,4-dioxygenase
CDG62_RS15120	COG3485	protocatechuate 3,4-dioxygenase
CDG62_RS15125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDG62_RS15130	COG2271	Major facilitator Superfamily
CDG62_RS15135	COG0596	Alpha beta hydrolase
CDG62_RS15140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDG62_RS15145	COG0183	Belongs to the thiolase family
CDG62_RS15150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_RS15155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG62_RS15160	COG1414	Transcriptional regulator
CDG62_RS15185	COG1113	amino acid transport
CDG62_RS15195	COG3724	N-succinylarginine dihydrolase activity
CDG62_RS15200	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_RS15205	COG3138	arginine N-succinyltransferase
CDG62_RS15215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG62_RS15220	COG1522	sequence-specific DNA binding
CDG62_RS15230	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_RS15235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG62_RS15245	COG1113	amino acid transport
CDG62_RS15260	COG1271	oxidase subunit
CDG62_RS15265	COG1294	oxidase, subunit
CDG62_RS15275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG62_RS15295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_RS15305	COG1522	sequence-specific DNA binding
CDG62_RS15315	COG0583	DNA-binding transcription factor activity
CDG62_RS15320	COG2814	Major facilitator Superfamily
CDG62_RS15330	COG0737	Belongs to the 5'-nucleotidase family
CDG62_RS15345	COG3188	usher protein
CDG62_RS15405	COG1802	Transcriptional regulator
CDG62_RS15415	COG2186	Transcriptional regulator
CDG62_RS15425	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_RS15435	COG2271	Major facilitator Superfamily
CDG62_RS15440	COG2721	sulfolactate sulfo-lyase activity
CDG62_RS15445	COG0697	spore germination
CDG62_RS15450	COG0745	RESPONSE REGULATOR receiver
CDG62_RS15455	COG2205	protein histidine kinase activity
CDG62_RS15460	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CDG62_RS15465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDG62_RS15470	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG62_RS15475	COG1968	undecaprenyl-diphosphatase activity
CDG62_RS15495	COG1215	transferase activity, transferring glycosyl groups
CDG62_RS15510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDG62_RS15535	COG3177	Filamentation induced by cAMP protein fic
CDG62_RS15540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG62_RS15570	COG0745	RESPONSE REGULATOR receiver
CDG62_RS15575	COG0642	Histidine kinase
CDG62_RS15590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDG62_RS15615	COG2816	NAD+ diphosphatase activity
CDG62_RS15620	COG3046	protein related to deoxyribodipyrimidine photolyase
CDG62_RS15635	COG2351	hydroxyisourate hydrolase activity
CDG62_RS15655	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_RS15665	COG2199	diguanylate cyclase activity
CDG62_RS15665	COG2203	Gaf domain
CDG62_RS15685	COG3328	transposase activity
CDG62_RS15720	COG0582	viral genome integration into host DNA
CDG62_RS15730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG62_RS15735	COG2814	Major facilitator Superfamily
CDG62_RS15740	COG1566	PFAM secretion protein HlyD family protein
CDG62_RS15745	COG2050	protein possibly involved in aromatic compounds catabolism
CDG62_RS15760	COG1090	epimerase
CDG62_RS15770	COG2203	Gaf domain
CDG62_RS15770	COG4251	negative regulation of phosphorylation
CDG62_RS15770	COG5001	Diguanylate cyclase
CDG62_RS15770	COG3706	GGDEF domain
CDG62_RS15775	COG0420	3'-5' exonuclease activity
CDG62_RS15805	COG0735	belongs to the Fur family
CDG62_RS15810	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG62_RS15815	COG2914	Belongs to the UPF0125 (RnfH) family
CDG62_RS15830	COG0121	glutamine amidotransferase
CDG62_RS15845	COG0756	dUTP diphosphatase activity
CDG62_RS15850	COG0210	DNA helicase
CDG62_RS15855	COG2885	chlorophyll binding
CDG62_RS15860	COG0204	Acyl-transferase
CDG62_RS15870	COG0850	regulation of cytokinetic process
CDG62_RS15875	COG2894	cell division
CDG62_RS15880	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDG62_RS15895	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDG62_RS15895	COG1674	ftsk spoiiie
CDG62_RS15900	COG0492	ferredoxin-NADP+ reductase activity
CDG62_RS15905	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDG62_RS15915	COG0456	acetyltransferase
CDG62_RS15955	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDG62_RS15970	COG1981	membrane
CDG62_RS15980	COG1113	amino acid transport
CDG62_RS15985	COG0251	oxidation-reduction process
CDG62_RS15995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG62_RS16025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG62_RS16035	COG2076	Multidrug Resistance protein
CDG62_RS16050	COG2132	Multicopper oxidase
CDG62_RS16060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDG62_RS16075	COG4269	membrane
CDG62_RS16095	COG1968	undecaprenyl-diphosphatase activity
CDG62_RS16100	COG1214	PFAM Peptidase M22, glycoprotease
CDG62_RS16105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG62_RS16110	COG0494	nUDIX hydrolase
CDG62_RS16160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG62_RS16170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG62_RS16210	COG2814	Major facilitator Superfamily
CDG62_RS16245	COG2853	Lipoprotein
CDG62_RS16250	COG2208	phosphoserine phosphatase activity
CDG62_RS16260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG62_RS16265	COG1764	response to oxidative stress
CDG62_RS16295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG62_RS16295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG62_RS16310	COG0037	tRNA processing
CDG62_RS16320	COG0248	Ppx GppA phosphatase
CDG62_RS16345	COG0072	phenylalanine-tRNA ligase activity
CDG62_RS16390	COG1238	metal cluster binding
CDG62_RS16400	COG0625	glutathione transferase activity
CDG62_RS16420	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_RS16425	COG3028	Belongs to the UPF0307 family
CDG62_RS16435	COG1660	Displays ATPase and GTPase activities
CDG62_RS16440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDG62_RS16450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDG62_RS16455	COG0617	tRNA 3'-terminal CCA addition
CDG62_RS16460	COG1555	photosystem II stabilization
CDG62_RS16465	COG3956	TIGRFAM MazG family protein
CDG62_RS16475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG62_RS16490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG62_RS16495	COG0784	Response regulator, receiver
CDG62_RS16495	COG5002	protein histidine kinase activity
CDG62_RS16495	COG2205	protein histidine kinase activity
CDG62_RS16500	COG1024	Enoyl-CoA hydratase
CDG62_RS16505	COG2084	Dehydrogenase
CDG62_RS16510	COG3622	Belongs to the hyi family
CDG62_RS16525	COG0004	ammonium transporteR
CDG62_RS16545	COG2814	Major facilitator Superfamily
CDG62_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS16610	COG0210	DNA helicase
CDG62_RS16615	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG62_RS16670	COG3328	transposase activity
CDG62_RS16690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG62_RS16695	COG0671	phosphoesterase, PA-phosphatase related
CDG62_RS16700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDG62_RS16715	COG0084	hydrolase, TatD family'
CDG62_RS16730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG62_RS16745	COG0793	Belongs to the peptidase S41A family
CDG62_RS16770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDG62_RS16775	COG0280	phosphate acetyltransferase
CDG62_RS16775	COG0857	belongs to the CobB CobQ family
CDG62_RS16790	COG3328	transposase activity
CDG62_RS16800	COG2318	DinB family
CDG62_RS16805	COG0697	spore germination
CDG62_RS16810	COG2207	Transcriptional regulator
CDG62_RS16810	COG1917	Cupin 2, conserved barrel domain protein
CDG62_RS16820	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG62_RS16820	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG62_RS16840	COG0740	serine-type endopeptidase activity
CDG62_RS16850	COG4771	TonB-dependent receptor
CDG62_RS16855	COG4774	siderophore transport
CDG62_RS16865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG62_RS16875	COG2813	Specifically methylates the guanine in position
CDG62_RS16875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG62_RS16980	COG0788	formyltetrahydrofolate deformylase activity
CDG62_RS17005	COG4651	solute:proton antiporter activity
CDG62_RS17005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG62_RS17035	COG1929	Belongs to the glycerate kinase type-1 family
CDG62_RS17070	COG2900	Belongs to the SlyX family
CDG62_RS17075	COG0488	(ABC) transporter
CDG62_RS17085	COG1560	Kdo2-lipid A biosynthetic process
CDG62_RS17145	COG0473	3-isopropylmalate dehydrogenase activity
CDG62_RS17160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG62_RS17170	COG0583	DNA-binding transcription factor activity
CDG62_RS17205	COG1280	lysine exporter protein (LysE YggA)
CDG62_RS17220	COG1960	acyl-CoA dehydrogenase activity
CDG62_RS17255	COG0583	DNA-binding transcription factor activity
CDG62_RS17270	COG0564	pseudouridine synthase activity
CDG62_RS17280	COG1530	ribonuclease E activity
CDG62_RS17285	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_RS17310	COG1983	PspC domain protein
CDG62_RS17335	COG0751	glycine-tRNA ligase activity
CDG62_RS17365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDG62_RS17380	COG2226	methyltransferase
CDG62_RS17395	COG0493	'glutamate synthase
CDG62_RS17395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG62_RS17405	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDG62_RS17410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG62_RS17415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDG62_RS17425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG62_RS17435	COG0644	oxidoreductase
CDG62_RS17435	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CDG62_RS17445	COG0425	Belongs to the sulfur carrier protein TusA family
CDG62_RS17450	COG4535	Mg2 and Co2 transporter CorC
CDG62_RS17455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDG62_RS17460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG62_RS17480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDG62_RS17490	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDG62_RS17510	COG2841	Protein conserved in bacteria
CDG62_RS17515	COG0598	Magnesium transport protein CorA
CDG62_RS17520	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG62_RS17530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDG62_RS17535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG62_RS17540	COG1074	ATP-dependent DNA helicase activity
CDG62_RS17545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDG62_RS17575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG62_RS17595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG62_RS17605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG62_RS17610	COG2111	Na H antiporter
CDG62_RS17610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG62_RS17615	COG1006	Multisubunit Na H antiporter MnhC subunit
CDG62_RS17620	COG0651	ATP synthesis coupled electron transport
CDG62_RS17625	COG1863	multisubunit Na H antiporter MnhE subunit
CDG62_RS17630	COG2212	antiporter activity
CDG62_RS17635	COG1320	monovalent cation:proton antiporter activity
CDG62_RS17640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG62_RS17650	COG0195	Participates in both transcription termination and antitermination
CDG62_RS17710	COG0237	dephospho-CoA kinase activity
CDG62_RS17720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG62_RS17730	COG0497	DNA recombination
CDG62_RS17735	COG1678	Uncharacterized ACR, COG1678
CDG62_RS17740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDG62_RS17745	COG1566	PFAM secretion protein HlyD family protein
CDG62_RS17755	COG1289	transmembrane transporter activity
CDG62_RS17770	COG1132	(ABC) transporter
CDG62_RS17775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDG62_RS17855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG62_RS17880	COG0326	Molecular chaperone. Has ATPase activity
CDG62_RS17890	COG3047	cAMP biosynthetic process
CDG62_RS17895	COG2056	Na+-H+ antiporter family
CDG62_RS17920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDG62_RS17930	COG0085	RNA polymerase activity
CDG62_RS17935	COG0222	ribosome binding
CDG62_RS17940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDG62_RS17945	COG0081	regulation of translation
CDG62_RS17950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDG62_RS18000	COG0546	phosphoglycolate phosphatase activity
CDG62_RS18030	COG0824	Thioesterase
CDG62_RS18050	COG0181	hydroxymethylbilane synthase activity
CDG62_RS18060	COG3275	phosphorelay sensor kinase activity
CDG62_RS18080	COG1538	Outer membrane efflux protein
CDG62_RS18090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDG62_RS18100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDG62_RS18105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDG62_RS18110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG62_RS18115	COG0772	Belongs to the SEDS family
CDG62_RS18120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDG62_RS18140	COG4974	Belongs to the 'phage' integrase family
CDG62_RS18145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG62_RS18160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG62_RS18170	COG2197	response regulator
CDG62_RS18185	COG0793	Belongs to the peptidase S41A family
CDG62_RS18190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDG62_RS18195	COG0795	lipopolysaccharide-transporting ATPase activity
CDG62_RS18200	COG0795	lipopolysaccharide-transporting ATPase activity
CDG62_RS18220	COG0586	Pfam SNARE associated Golgi protein
CDG62_RS18235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG62_RS18235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG62_RS18245	COG0004	ammonium transporteR
CDG62_RS18250	COG0347	Belongs to the P(II) protein family
CDG62_RS18260	COG0606	chelatase, subunit chli
CDG62_RS18280	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG62_RS18295	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_RS18305	COG0477	Major facilitator Superfamily
CDG62_RS18310	COG2860	membrane
CDG62_RS18315	COG3012	SEC-C Motif Domain Protein
CDG62_RS18320	COG1253	flavin adenine dinucleotide binding
CDG62_RS18350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG62_RS18425	COG0758	DNA mediated transformation
CDG62_RS18435	COG0697	spore germination
CDG62_RS18445	COG0386	Belongs to the glutathione peroxidase family
CDG62_RS18480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG62_RS18530	COG1121	(ABC) transporter
CDG62_RS18535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG62_RS18550	COG2837	iron assimilation
CDG62_RS18585	COG0281	malic enzyme
CDG62_RS18610	COG2267	carboxylic ester hydrolase activity
CDG62_RS18635	COG0519	Catalyzes the synthesis of GMP from XMP
CDG62_RS18635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG62_RS18645	COG2259	Doxx family
CDG62_RS18650	COG0586	Pfam SNARE associated Golgi protein
CDG62_RS18665	COG1192	Involved in chromosome partitioning
CDG62_RS18675	COG0271	Belongs to the BolA IbaG family
CDG62_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS18745	COG2986	histidine ammonia-lyase
CDG62_RS18760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG62_RS18770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG62_RS18790	COG0583	DNA-binding transcription factor activity
CDG62_RS18795	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDG62_RS18810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDG62_RS18820	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDG62_RS18825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDG62_RS18835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG62_RS18840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG62_RS18845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG62_RS18860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG62_RS18870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG62_RS18880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG62_RS18910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_RS18920	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDG62_RS18950	COG0728	peptidoglycan biosynthetic process
CDG62_RS18955	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDG62_RS18965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG62_RS18975	COG3307	-O-antigen
CDG62_RS18985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG62_RS18990	COG0546	phosphoglycolate phosphatase activity
CDG62_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_RS19015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG62_RS19015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDG62_RS19020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_RS19025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_RS19030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_RS19035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG62_RS19040	COG1116	anion transmembrane transporter activity
CDG62_RS19045	COG1309	transcriptional regulator
CDG62_RS19060	COG0196	riboflavin kinase activity
CDG62_RS19065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG62_RS19070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDG62_RS19075	COG1047	Peptidyl-prolyl cis-trans
CDG62_RS19095	COG2133	pyrroloquinoline quinone binding
CDG62_RS19125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG62_RS19130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG62_RS19135	COG2951	lytic endotransglycosylase activity
CDG62_RS19140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDG62_RS19155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG62_RS19175	COG0861	Integral membrane protein TerC family
CDG62_RS19185	COG0754	glutathionylspermidine amidase activity
CDG62_RS19195	COG0402	S-adenosylhomocysteine deaminase activity
CDG62_RS19215	COG1230	cation diffusion facilitator family transporter
CDG62_RS19235	COG0706	membrane insertase activity
CDG62_RS19240	COG0759	Could be involved in insertion of integral membrane proteins into the membrane