locus-tag	class	description
BEN74_RS00030	COG1981	membrane
BEN74_RS00050	COG1136	(ABC) transporter
BEN74_RS00110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BEN74_RS00135	COG0640	Transcriptional regulator
BEN74_RS00160	COG0582	viral genome integration into host DNA
BEN74_RS00165	COG2369	cell adhesion
BEN74_RS00190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BEN74_RS00245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BEN74_RS00255	COG4115	mRNA cleavage
BEN74_RS00260	COG2161	toxin-antitoxin pair type II binding
BEN74_RS00340	COG1192	Involved in chromosome partitioning
BEN74_RS00370	COG1373	ATPase (AAA superfamily
BEN74_RS00390	COG1475	DNA binding
BEN74_RS00395	COG1192	Involved in chromosome partitioning
BEN74_RS00450	COG0488	(ABC) transporter
BEN74_RS00455	COG3173	Aminoglycoside phosphotransferase
BEN74_RS00470	COG1660	Displays ATPase and GTPase activities
BEN74_RS00540	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BEN74_RS00570	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN74_RS00590	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN74_RS00595	COG3657	addiction module killer protein
BEN74_RS00635	COG2076	Multidrug Resistance protein
BEN74_RS00660	COG0406	alpha-ribazole phosphatase activity
BEN74_RS00675	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BEN74_RS00700	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN74_RS00705	COG3657	addiction module killer protein
BEN74_RS00765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN74_RS00795	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BEN74_RS00815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEN74_RS00860	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BEN74_RS00935	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN74_RS00940	COG3657	addiction module killer protein
BEN74_RS01040	COG1192	Involved in chromosome partitioning
BEN74_RS01110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN74_RS01145	COG2826	transposase and inactivated derivatives, IS30 family
BEN74_RS01165	COG0673	inositol 2-dehydrogenase activity
BEN74_RS01170	COG1324	tolerance protein
BEN74_RS01200	COG2826	transposase and inactivated derivatives, IS30 family
BEN74_RS01205	COG2826	transposase and inactivated derivatives, IS30 family
BEN74_RS01225	COG1525	nuclease
BEN74_RS01250	COG0739	heme binding
BEN74_RS01250	COG1196	nuclear chromosome segregation
BEN74_RS01250	COG0741	lytic transglycosylase activity
BEN74_RS01265	COG0741	lytic transglycosylase activity
BEN74_RS01265	COG0739	heme binding
BEN74_RS01265	COG1196	nuclear chromosome segregation
BEN74_RS01290	COG0372	Belongs to the citrate synthase family
BEN74_RS01300	COG1058	Belongs to the CinA family
BEN74_RS01300	COG1546	Belongs to the CinA family
BEN74_RS01345	COG0415	Belongs to the DNA photolyase family
BEN74_RS01385	COG1131	(ABC) transporter
BEN74_RS01390	COG0842	Transport permease protein
BEN74_RS01395	COG0842	Transport permease protein
BEN74_RS01440	COG4680	protein conserved in bacteria
BEN74_RS01450	COG0300	oxidoreductase activity
BEN74_RS01455	COG0288	reversible hydration of carbon dioxide
BEN74_RS01510	COG3646	Phage regulatory protein
BEN74_RS01570	COG1846	Transcriptional regulator
BEN74_RS01595	COG0697	spore germination
BEN74_RS01695	COG2814	Major facilitator Superfamily
BEN74_RS01705	COG0439	Biotin carboxylase
BEN74_RS01770	COG0596	Alpha beta hydrolase
BEN74_RS01900	COG0583	DNA-binding transcription factor activity
BEN74_RS01920	COG0730	response to heat
BEN74_RS01925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN74_RS01930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BEN74_RS01940	COG1629	transport
BEN74_RS01950	COG1595	DNA-templated transcription, initiation
BEN74_RS01955	COG1073	alpha beta
BEN74_RS01960	COG1073	alpha beta
BEN74_RS01965	COG2207	Transcriptional regulator
BEN74_RS01970	COG0318	PFAM AMP-dependent synthetase and ligase
BEN74_RS01975	COG1309	transcriptional regulator
BEN74_RS01980	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS01985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BEN74_RS01990	COG1024	Enoyl-CoA hydratase
BEN74_RS01995	COG4770	biotin carboxylase activity
BEN74_RS02010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BEN74_RS02015	COG1944	ATP diphosphatase activity
BEN74_RS02025	COG3706	GGDEF domain
BEN74_RS02030	COG0745	RESPONSE REGULATOR receiver
BEN74_RS02035	COG2205	protein histidine kinase activity
BEN74_RS02045	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BEN74_RS02050	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BEN74_RS02060	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BEN74_RS02075	COG0318	PFAM AMP-dependent synthetase and ligase
BEN74_RS02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEN74_RS02090	COG2814	Major facilitator Superfamily
BEN74_RS02105	COG0583	DNA-binding transcription factor activity
BEN74_RS02110	COG4948	Mandelate Racemase Muconate Lactonizing
BEN74_RS02115	COG4829	muconolactone delta-isomerase
BEN74_RS02125	COG4638	Rieske (2fe-2S)
BEN74_RS02130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BEN74_RS02135	COG0543	2 iron, 2 sulfur cluster binding
BEN74_RS02135	COG0633	Ferredoxin
BEN74_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
BEN74_RS02145	COG3135	benzoate transporter
BEN74_RS02150	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BEN74_RS02155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BEN74_RS02160	COG0183	Belongs to the thiolase family
BEN74_RS02165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BEN74_RS02170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BEN74_RS02175	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS02180	COG0583	DNA-binding transcription factor activity
BEN74_RS02185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BEN74_RS02205	COG0583	DNA-binding transcription factor activity
BEN74_RS02210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BEN74_RS02215	COG0427	acetyl-CoA hydrolase
BEN74_RS02220	COG0183	Belongs to the thiolase family
BEN74_RS02225	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS02260	COG0789	Transcriptional regulator
BEN74_RS02270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BEN74_RS02275	COG0640	Transcriptional regulator
BEN74_RS02295	COG3122	Protein conserved in bacteria
BEN74_RS02300	COG0668	transmembrane transport
BEN74_RS02315	COG3676	manually curated
BEN74_RS02330	COG0789	Transcriptional regulator
BEN74_RS02345	COG0583	DNA-binding transcription factor activity
BEN74_RS02390	COG1132	(ABC) transporter
BEN74_RS02410	COG2814	Major facilitator Superfamily
BEN74_RS02420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BEN74_RS02425	COG0488	(ABC) transporter
BEN74_RS02440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BEN74_RS02445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEN74_RS02460	COG0436	Aminotransferase
BEN74_RS02465	COG0697	spore germination
BEN74_RS02520	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS02525	COG0583	DNA-binding transcription factor activity
BEN74_RS02530	COG1525	nuclease
BEN74_RS02555	COG0424	maF-like protein
BEN74_RS02570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BEN74_RS02575	COG2207	Transcriptional regulator
BEN74_RS02580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN74_RS02585	COG0730	response to heat
BEN74_RS02590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BEN74_RS02610	COG2315	Protein conserved in bacteria
BEN74_RS02655	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS02660	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS02715	COG0552	protein localization to endoplasmic reticulum
BEN74_RS02760	COG0133	tryptophan synthase activity
BEN74_RS02775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BEN74_RS02795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BEN74_RS02845	COG1294	oxidase, subunit
BEN74_RS02850	COG4890	Cyd operon protein YbgT
BEN74_RS02875	COG1218	3'(2'),5'-bisphosphate nucleotidase
BEN74_RS02880	COG1011	Hydrolase
BEN74_RS02885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BEN74_RS02895	COG2137	regulation of response to DNA damage stimulus
BEN74_RS02910	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN74_RS02920	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN74_RS02930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BEN74_RS02945	COG0575	Belongs to the CDS family
BEN74_RS02950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BEN74_RS02970	COG3852	Histidine kinase
BEN74_RS02985	COG0772	Belongs to the SEDS family
BEN74_RS03000	COG0148	phosphopyruvate hydratase activity
BEN74_RS03020	COG0583	DNA-binding transcription factor activity
BEN74_RS03035	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEN74_RS03035	COG1902	pentaerythritol trinitrate reductase activity
BEN74_RS03045	COG2267	carboxylic ester hydrolase activity
BEN74_RS03050	COG3878	Protein conserved in bacteria
BEN74_RS03055	COG0583	DNA-binding transcription factor activity
BEN74_RS03060	COG0583	DNA-binding transcription factor activity
BEN74_RS03065	COG0024	Methionine aminopeptidase
BEN74_RS03090	COG1113	amino acid transport
BEN74_RS03125	COG1464	Belongs to the NlpA lipoprotein family
BEN74_RS03130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BEN74_RS03135	COG2011	ABC-type metal ion transport system permease component
BEN74_RS03190	COG0729	surface antigen
BEN74_RS03195	COG0477	Major facilitator Superfamily
BEN74_RS03205	COG3153	acetyltransferase
BEN74_RS03235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEN74_RS03240	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS03260	COG2890	protein-(glutamine-N5) methyltransferase activity
BEN74_RS03265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BEN74_RS03285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEN74_RS03290	COG4682	membrane
BEN74_RS03315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BEN74_RS03320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BEN74_RS03325	COG1845	cytochrome c oxidase, subunit III
BEN74_RS03330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BEN74_RS03350	COG0360	Binds together with S18 to 16S ribosomal RNA
BEN74_RS03365	COG0305	Participates in initiation and elongation during chromosome replication
BEN74_RS03380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BEN74_RS03390	COG1305	Transglutaminase-like
BEN74_RS03400	COG2308	Evidence 4 Homologs of previously reported genes of
BEN74_RS03410	COG0069	glutamate synthase activity
BEN74_RS03430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEN74_RS03435	COG1454	alcohol dehydrogenase
BEN74_RS03455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BEN74_RS03470	COG0183	Belongs to the thiolase family
BEN74_RS03480	COG0583	DNA-binding transcription factor activity
BEN74_RS03485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BEN74_RS03495	COG3135	benzoate transporter
BEN74_RS03500	COG1309	transcriptional regulator
BEN74_RS03515	COG0589	response to stress
BEN74_RS03520	COG0589	response to stress
BEN74_RS03540	COG0308	aminopeptidase N
BEN74_RS03565	COG1253	flavin adenine dinucleotide binding
BEN74_RS03590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BEN74_RS03595	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BEN74_RS03610	COG2431	L-lysine efflux transmembrane transporter activity
BEN74_RS03615	COG0284	orotidine-5'-phosphate decarboxylase activity
BEN74_RS03640	COG0776	regulation of translation
BEN74_RS03670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BEN74_RS03705	COG0084	hydrolase, TatD family'
BEN74_RS03725	COG1663	tetraacyldisaccharide 4'-kinase activity
BEN74_RS03730	COG1132	(ABC) transporter
BEN74_RS03740	COG0811	peptide transport
BEN74_RS03745	COG1475	DNA binding
BEN74_RS03750	COG1192	Involved in chromosome partitioning
BEN74_RS03755	COG0357	Ribosomal RNA small subunit methyltransferase G
BEN74_RS03760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BEN74_RS03775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEN74_RS03780	COG1923	regulation of RNA biosynthetic process
BEN74_RS03790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BEN74_RS03795	COG0802	atpase or kinase
BEN74_RS03815	COG1187	pseudouridine synthase activity
BEN74_RS03820	COG2707	UPF0756 membrane protein
BEN74_RS04095	COG0305	Participates in initiation and elongation during chromosome replication
BEN74_RS04200	COG0714	Associated with various cellular activities
BEN74_RS04205	COG2879	small protein
BEN74_RS04210	COG1966	Carbon starvation protein
BEN74_RS04220	COG1509	lysine 2,3-aminomutase activity
BEN74_RS04260	COG1067	ATP-dependent peptidase activity
BEN74_RS04265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BEN74_RS04270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BEN74_RS04275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BEN74_RS04275	COG0047	phosphoribosylformylglycinamidine synthase activity
BEN74_RS04285	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BEN74_RS04295	COG0714	Associated with various cellular activities
BEN74_RS04300	COG3831	ATPase activity
BEN74_RS04320	COG2255	four-way junction helicase activity
BEN74_RS04330	COG0824	Thioesterase
BEN74_RS04355	COG0823	Involved in the tonB-independent uptake of proteins
BEN74_RS04375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEN74_RS04410	COG0628	permease
BEN74_RS04415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BEN74_RS04420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BEN74_RS04425	COG0596	Alpha beta hydrolase
BEN74_RS04440	COG0658	competence protein
BEN74_RS04440	COG2333	competence protein COMEC
BEN74_RS04445	COG1136	(ABC) transporter
BEN74_RS04465	COG1671	Belongs to the UPF0178 family
BEN74_RS04490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN74_RS04505	COG1301	dicarboxylic acid transport
BEN74_RS04525	COG2318	DinB family
BEN74_RS04545	COG1280	lysine exporter protein (LysE YggA)
BEN74_RS04550	COG1522	sequence-specific DNA binding
BEN74_RS04585	COG0582	viral genome integration into host DNA
BEN74_RS04720	COG5410	chromosome segregation
BEN74_RS04870	COG1301	dicarboxylic acid transport
BEN74_RS04880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BEN74_RS04890	COG3139	Protein of unknown function (DUF1315)
BEN74_RS04895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BEN74_RS04900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEN74_RS04910	COG0494	nUDIX hydrolase
BEN74_RS04940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BEN74_RS04955	COG1720	tRNA m6t6A37 methyltransferase activity
BEN74_RS04990	COG0789	Transcriptional regulator
BEN74_RS04995	COG0431	NADPH-dependent FMN reductase
BEN74_RS05000	COG0798	PFAM Bile acid sodium symporter
BEN74_RS05005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEN74_RS05010	COG0640	Transcriptional regulator
BEN74_RS05015	COG0826	peptidase U32
BEN74_RS05020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BEN74_RS05025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BEN74_RS05035	COG3634	alkyl hydroperoxide reductase activity
BEN74_RS05055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BEN74_RS05100	COG0582	viral genome integration into host DNA
BEN74_RS05105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEN74_RS05345	COG4695	Portal protein
BEN74_RS05355	COG1131	(ABC) transporter
BEN74_RS05360	COG0842	Transport permease protein
BEN74_RS05380	COG2951	lytic endotransglycosylase activity
BEN74_RS05425	COG0052	Belongs to the universal ribosomal protein uS2 family
BEN74_RS05435	COG0436	Aminotransferase
BEN74_RS05440	COG1280	lysine exporter protein (LysE YggA)
BEN74_RS05485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BEN74_RS05490	COG3161	chorismate lyase activity
BEN74_RS05500	COG0174	glutamine synthetase
BEN74_RS05515	COG0512	Glutamine amidotransferase of anthranilate synthase
BEN74_RS05540	COG0302	gtp cyclohydrolase
BEN74_RS05550	COG3706	GGDEF domain
BEN74_RS05555	COG3739	integral membrane protein
BEN74_RS05575	COG1741	Belongs to the pirin family
BEN74_RS05585	COG1113	amino acid transport
BEN74_RS05595	COG3724	N-succinylarginine dihydrolase activity
BEN74_RS05600	COG1012	belongs to the aldehyde dehydrogenase family
BEN74_RS05615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEN74_RS05640	COG1309	transcriptional regulator
BEN74_RS05645	COG0579	oxidoreductase
BEN74_RS05685	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BEN74_RS05700	COG0625	glutathione transferase activity
BEN74_RS05715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BEN74_RS05725	COG1113	amino acid transport
BEN74_RS05730	COG1448	Aminotransferase
BEN74_RS05760	COG0582	viral genome integration into host DNA
BEN74_RS05770	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BEN74_RS05805	COG0745	RESPONSE REGULATOR receiver
BEN74_RS05810	COG0642	Histidine kinase
BEN74_RS05825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BEN74_RS05845	COG3040	lipid binding
BEN74_RS05865	COG2816	NAD+ diphosphatase activity
BEN74_RS05870	COG3046	protein related to deoxyribodipyrimidine photolyase
BEN74_RS05885	COG2351	hydroxyisourate hydrolase activity
BEN74_RS05905	COG1136	(ABC) transporter
BEN74_RS05910	COG4591	ABC-type transport system involved in lipoprotein release permease component
BEN74_RS05940	COG3214	Protein conserved in bacteria
BEN74_RS05955	COG0642	Histidine kinase
BEN74_RS05960	COG0745	RESPONSE REGULATOR receiver
BEN74_RS05985	COG3038	cytochrome b561
BEN74_RS05990	COG0300	oxidoreductase activity
BEN74_RS06000	COG1022	Amp-dependent synthetase and ligase
BEN74_RS06045	COG3311	Transcriptional regulator
BEN74_RS06055	COG3152	Membrane
BEN74_RS06085	COG1902	pentaerythritol trinitrate reductase activity
BEN74_RS06085	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEN74_RS06090	COG0277	FAD linked oxidase domain protein
BEN74_RS06100	COG2186	Transcriptional regulator
BEN74_RS06105	COG1620	l-lactate permease
BEN74_RS06125	COG3706	GGDEF domain
BEN74_RS06130	COG0418	dihydroorotase activity
BEN74_RS06135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEN74_RS06145	COG0833	amino acid
BEN74_RS06155	COG0833	amino acid
BEN74_RS06185	COG4172	Belongs to the ABC transporter superfamily
BEN74_RS06190	COG4239	(ABC) transporter, permease
BEN74_RS06195	COG4174	ABC transporter (Permease)
BEN74_RS06205	COG0741	lytic transglycosylase activity
BEN74_RS06205	COG1388	LysM domain
BEN74_RS06225	COG0657	acetylesterase activity
BEN74_RS06255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BEN74_RS06260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BEN74_RS06285	COG0006	proline dipeptidase activity
BEN74_RS06340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN74_RS06350	COG1271	oxidase subunit
BEN74_RS06355	COG1294	oxidase, subunit
BEN74_RS06365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEN74_RS06390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BEN74_RS06395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN74_RS06420	COG3712	iron ion homeostasis
BEN74_RS06430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BEN74_RS06445	COG2234	aminopeptidase activity
BEN74_RS06455	COG3384	dioxygenase
BEN74_RS06465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEN74_RS06470	COG2878	Part of a membrane complex involved in electron transport
BEN74_RS06475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BEN74_RS06505	COG0742	ribosomal rna small subunit methyltransferase
BEN74_RS06525	COG3015	lipoprotein NlpE involved in copper resistance
BEN74_RS06550	COG2304	oxidoreductase activity
BEN74_RS06590	COG1358	cellular component organization or biogenesis
BEN74_RS06615	COG4245	von Willebrand factor, type A
BEN74_RS06630	COG0459	protein refolding
BEN74_RS06645	COG1597	lipid kinase activity
BEN74_RS06650	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BEN74_RS06725	COG0625	glutathione transferase activity
BEN74_RS06760	COG2268	Band 7 protein
BEN74_RS06765	COG1649	PFAM Uncharacterised BCR, COG1649
BEN74_RS06765	COG0726	polysaccharide deacetylase
BEN74_RS06775	COG1215	transferase activity, transferring glycosyl groups
BEN74_RS06780	COG0726	polysaccharide deacetylase
BEN74_RS06780	COG1649	PFAM Uncharacterised BCR, COG1649
BEN74_RS06790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BEN74_RS06800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEN74_RS06820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BEN74_RS06825	COG1053	succinate dehydrogenase
BEN74_RS06830	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BEN74_RS06835	COG2009	succinate dehydrogenase
BEN74_RS06855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BEN74_RS06855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BEN74_RS06890	COG2321	neutral zinc metallopeptidase
BEN74_RS06895	COG2354	Protein conserved in bacteria
BEN74_RS06920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEN74_RS06925	COG1773	rubredoxin
BEN74_RS06930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN74_RS06940	COG0583	DNA-binding transcription factor activity
BEN74_RS06965	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BEN74_RS06970	COG4181	ATPase activity
BEN74_RS07000	COG4771	TonB-dependent receptor
BEN74_RS07025	COG0306	phosphate transporter
BEN74_RS07040	COG2852	Protein conserved in bacteria
BEN74_RS07085	COG2199	diguanylate cyclase activity
BEN74_RS07085	COG2203	Gaf domain
BEN74_RS07095	COG1285	pathogenesis
BEN74_RS07100	COG4681	YaeQ
BEN74_RS07105	COG0523	cobalamin synthesis protein
BEN74_RS07120	COG1607	acyl-coa hydrolase
BEN74_RS07130	COG1752	Esterase of the alpha-beta hydrolase superfamily
BEN74_RS07135	COG1115	amino acid carrier protein
BEN74_RS07140	COG0786	glutamate:sodium symporter activity
BEN74_RS07155	COG2814	Major facilitator Superfamily
BEN74_RS07160	COG1289	transmembrane transporter activity
BEN74_RS07170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BEN74_RS07235	COG2832	Protein of unknown function (DUF454)
BEN74_RS07245	COG5510	response to toxic substance
BEN74_RS07250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEN74_RS07260	COG2198	Histidine kinase
BEN74_RS07260	COG0643	Histidine kinase
BEN74_RS07265	COG0840	transmembrane signaling receptor activity
BEN74_RS07295	COG0442	prolyl-tRNA aminoacylation
BEN74_RS07335	COG0489	protein tyrosine kinase activity
BEN74_RS07355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEN74_RS07355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEN74_RS07365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEN74_RS07375	COG4716	Myosin-crossreactive antigen
BEN74_RS07400	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BEN74_RS07410	COG2081	HI0933 family
BEN74_RS07415	COG0668	transmembrane transport
BEN74_RS07435	COG0583	DNA-binding transcription factor activity
BEN74_RS07465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN74_RS07470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BEN74_RS07475	COG0713	ATP synthesis coupled electron transport
BEN74_RS07485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN74_RS07500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BEN74_RS07520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN74_RS07530	COG2205	protein histidine kinase activity
BEN74_RS07535	COG0745	RESPONSE REGULATOR receiver
BEN74_RS07550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BEN74_RS07565	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BEN74_RS07575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN74_RS07635	COG3152	Membrane
BEN74_RS07645	COG0183	Belongs to the thiolase family
BEN74_RS07650	COG1024	Enoyl-CoA hydratase
BEN74_RS07650	COG1250	3-hydroxyacyl-CoA dehydrogenase
BEN74_RS07675	COG1272	protein, Hemolysin III
BEN74_RS07690	COG1408	metallophosphoesterase
BEN74_RS07695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEN74_RS07705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BEN74_RS07735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BEN74_RS07740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BEN74_RS07770	COG2132	Multicopper oxidase
BEN74_RS07785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BEN74_RS07800	COG4269	membrane
BEN74_RS07820	COG1968	undecaprenyl-diphosphatase activity
BEN74_RS07825	COG1214	PFAM Peptidase M22, glycoprotease
BEN74_RS07835	COG0494	nUDIX hydrolase
BEN74_RS07885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BEN74_RS07895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BEN74_RS07945	COG2853	Lipoprotein
BEN74_RS07960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BEN74_RS07965	COG1764	response to oxidative stress
BEN74_RS08015	COG0745	RESPONSE REGULATOR receiver
BEN74_RS08020	COG2205	protein histidine kinase activity
BEN74_RS08030	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS08035	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS08045	COG3223	Belongs to the PsiE family
BEN74_RS08070	COG0037	tRNA processing
BEN74_RS08080	COG0248	Ppx GppA phosphatase
BEN74_RS08105	COG0072	phenylalanine-tRNA ligase activity
BEN74_RS08110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BEN74_RS08160	COG1238	metal cluster binding
BEN74_RS08170	COG0625	glutathione transferase activity
BEN74_RS08180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BEN74_RS08195	COG0318	PFAM AMP-dependent synthetase and ligase
BEN74_RS08200	COG3028	Belongs to the UPF0307 family
BEN74_RS08205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEN74_RS08210	COG1660	Displays ATPase and GTPase activities
BEN74_RS08225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BEN74_RS08230	COG0617	tRNA 3'-terminal CCA addition
BEN74_RS08235	COG1555	photosystem II stabilization
BEN74_RS08240	COG3956	TIGRFAM MazG family protein
BEN74_RS08260	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BEN74_RS08355	COG0028	Belongs to the TPP enzyme family
BEN74_RS08385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN74_RS08390	COG1136	(ABC) transporter
BEN74_RS08390	COG0577	efflux transmembrane transporter activity
BEN74_RS08405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BEN74_RS08410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BEN74_RS08415	COG1162	GTPase activity
BEN74_RS08425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BEN74_RS08435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BEN74_RS08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BEN74_RS08450	COG2003	Belongs to the UPF0758 family
BEN74_RS08455	COG3781	membrane
BEN74_RS08470	COG2350	Protein conserved in bacteria
BEN74_RS08505	COG1607	acyl-coa hydrolase
BEN74_RS08570	COG1183	phosphatidylcholine synthase activity
BEN74_RS08575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BEN74_RS08680	COG0788	formyltetrahydrofolate deformylase activity
BEN74_RS08705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BEN74_RS08705	COG4651	solute:proton antiporter activity
BEN74_RS08735	COG0210	DNA helicase
BEN74_RS08740	COG1929	Belongs to the glycerate kinase type-1 family
BEN74_RS08780	COG2900	Belongs to the SlyX family
BEN74_RS08785	COG0488	(ABC) transporter
BEN74_RS08790	COG1560	Kdo2-lipid A biosynthetic process
BEN74_RS08875	COG0473	3-isopropylmalate dehydrogenase activity
BEN74_RS08910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BEN74_RS08915	COG0408	coproporphyrinogen oxidase activity
BEN74_RS08935	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS08945	COG0402	S-adenosylhomocysteine deaminase activity
BEN74_RS08950	COG1322	Protein conserved in bacteria
BEN74_RS08960	COG1322	Protein conserved in bacteria
BEN74_RS08965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BEN74_RS08975	COG0534	Mate efflux family protein
BEN74_RS08985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BEN74_RS08990	COG0254	rRNA binding
BEN74_RS09030	COG1192	Involved in chromosome partitioning
BEN74_RS09035	COG0628	permease
BEN74_RS09040	COG2032	superoxide dismutase activity
BEN74_RS09050	COG2814	Major facilitator Superfamily
BEN74_RS09070	COG0277	FAD linked oxidase domain protein
BEN74_RS09075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BEN74_RS09080	COG5006	permease, DMT superfamily
BEN74_RS09100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BEN74_RS09105	COG5380	lipid catabolic process
BEN74_RS09110	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BEN74_RS09120	COG0335	large ribosomal subunit rRNA binding
BEN74_RS09125	COG0336	Belongs to the RNA methyltransferase TrmD family
BEN74_RS09130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BEN74_RS09135	COG0228	four-way junction DNA binding
BEN74_RS09180	COG0194	GDP metabolic process
BEN74_RS09185	COG1758	RNA polymerase activity
BEN74_RS09190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BEN74_RS09240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BEN74_RS09245	COG1704	LemA family
BEN74_RS09255	COG0493	'glutamate synthase
BEN74_RS09260	COG0067	glutamate synthase
BEN74_RS09260	COG0069	glutamate synthase activity
BEN74_RS09260	COG0070	glutamate synthase
BEN74_RS09310	COG2226	methyltransferase
BEN74_RS09320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BEN74_RS09325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BEN74_RS09335	COG3116	cell division
BEN74_RS09345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BEN74_RS09350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BEN74_RS09360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEN74_RS09390	COG0488	(ABC) transporter
BEN74_RS09395	COG2873	o-acetylhomoserine
BEN74_RS09400	COG4221	oxidoreductase activity
BEN74_RS09405	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BEN74_RS09420	COG2111	Na H antiporter
BEN74_RS09420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BEN74_RS09425	COG1006	Multisubunit Na H antiporter MnhC subunit
BEN74_RS09430	COG0651	ATP synthesis coupled electron transport
BEN74_RS09435	COG1863	multisubunit Na H antiporter MnhE subunit
BEN74_RS09440	COG2212	antiporter activity
BEN74_RS09445	COG1320	monovalent cation:proton antiporter activity
BEN74_RS09455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BEN74_RS09460	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BEN74_RS09465	COG0195	Participates in both transcription termination and antitermination
BEN74_RS09470	COG0779	Required for maturation of 30S ribosomal subunits
BEN74_RS09520	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BEN74_RS09525	COG0237	dephospho-CoA kinase activity
BEN74_RS09535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEN74_RS09540	COG3123	guanosine phosphorylase activity
BEN74_RS09545	COG0497	DNA recombination
BEN74_RS09575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BEN74_RS09590	COG0704	Plays a role in the regulation of phosphate uptake
BEN74_RS09600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BEN74_RS09605	COG0494	nUDIX hydrolase
BEN74_RS09615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BEN74_RS09620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEN74_RS09625	COG0772	Belongs to the SEDS family
BEN74_RS09650	COG4974	Belongs to the 'phage' integrase family
BEN74_RS09655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BEN74_RS09665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BEN74_RS09685	COG2197	response regulator
BEN74_RS09700	COG0793	Belongs to the peptidase S41A family
BEN74_RS09705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BEN74_RS09710	COG0795	lipopolysaccharide-transporting ATPase activity
BEN74_RS09715	COG0795	lipopolysaccharide-transporting ATPase activity
BEN74_RS09740	COG0586	Pfam SNARE associated Golgi protein
BEN74_RS09755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEN74_RS09755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEN74_RS09765	COG0004	ammonium transporteR
BEN74_RS09770	COG0347	Belongs to the P(II) protein family
BEN74_RS09780	COG0606	chelatase, subunit chli
BEN74_RS09800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BEN74_RS09815	COG0318	PFAM AMP-dependent synthetase and ligase
BEN74_RS09825	COG0477	Major facilitator Superfamily
BEN74_RS09830	COG2860	membrane
BEN74_RS09835	COG3012	SEC-C Motif Domain Protein
BEN74_RS09840	COG1253	flavin adenine dinucleotide binding
BEN74_RS09850	COG2814	Major facilitator Superfamily
BEN74_RS09860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEN74_RS09870	COG0745	RESPONSE REGULATOR receiver
BEN74_RS09875	COG2205	protein histidine kinase activity
BEN74_RS09880	COG4452	Inner membrane protein CreD
BEN74_RS09915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BEN74_RS09935	COG3162	membrane
BEN74_RS09940	COG0784	Response regulator, receiver
BEN74_RS09940	COG2205	protein histidine kinase activity
BEN74_RS09965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BEN74_RS10015	COG1121	(ABC) transporter
BEN74_RS10020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BEN74_RS10035	COG2837	iron assimilation
BEN74_RS10085	COG0758	DNA mediated transformation
BEN74_RS10095	COG0697	spore germination
BEN74_RS10105	COG0386	Belongs to the glutathione peroxidase family
BEN74_RS10135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEN74_RS10140	COG0668	transmembrane transport
BEN74_RS10145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BEN74_RS10150	COG1519	Transferase
BEN74_RS10155	COG1902	pentaerythritol trinitrate reductase activity
BEN74_RS10180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BEN74_RS10210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN74_RS10210	COG0426	domain, Protein
BEN74_RS10215	COG2119	membrane
BEN74_RS10245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BEN74_RS10255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BEN74_RS10285	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BEN74_RS10295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BEN74_RS10300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BEN74_RS10305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BEN74_RS10310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BEN74_RS10380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEN74_RS10385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BEN74_RS10400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BEN74_RS10410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BEN74_RS10420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BEN74_RS10470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BEN74_RS10475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BEN74_RS10480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BEN74_RS10520	COG1194	a g-specific adenine glycosylase
BEN74_RS10535	COG2818	Glycosylase
BEN74_RS10540	COG1064	alcohol dehydrogenase
BEN74_RS10565	COG3307	-O-antigen
BEN74_RS10600	COG2233	PERMEase
BEN74_RS10630	COG0174	glutamine synthetase
BEN74_RS10645	COG0129	dihydroxy-acid dehydratase activity
BEN74_RS10680	COG0733	neurotransmitter:sodium symporter activity
BEN74_RS10685	COG3738	Protein conserved in bacteria
BEN74_RS10695	COG2814	Major facilitator Superfamily
BEN74_RS10725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BEN74_RS10730	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BEN74_RS10735	COG2951	lytic endotransglycosylase activity
BEN74_RS10740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BEN74_RS10755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BEN74_RS10780	COG0861	Integral membrane protein TerC family
BEN74_RS10795	COG0402	S-adenosylhomocysteine deaminase activity
BEN74_RS10805	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BEN74_RS10810	COG2261	transglycosylase associated protein
BEN74_RS10845	COG0706	membrane insertase activity
BEN74_RS10850	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BEN74_RS10855	COG0594	ribonuclease P activity
BEN74_RS10865	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BEN74_RS10870	COG0592	DNA-directed DNA polymerase activity
BEN74_RS10880	COG0187	DNA topoisomerase II activity
BEN74_RS10895	COG0488	(ABC) transporter
BEN74_RS10945	COG0657	acetylesterase activity
BEN74_RS10955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BEN74_RS10985	COG2814	Major facilitator Superfamily
BEN74_RS11000	COG0693	protein deglycase activity
BEN74_RS11015	COG1404	Belongs to the peptidase S8 family
BEN74_RS11030	COG1047	Peptidyl-prolyl cis-trans
BEN74_RS11040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BEN74_RS11045	COG0196	riboflavin kinase activity
BEN74_RS11060	COG1309	transcriptional regulator
BEN74_RS11070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEN74_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
BEN74_RS11105	COG0546	phosphoglycolate phosphatase activity
BEN74_RS11115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BEN74_RS11125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BEN74_RS11130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BEN74_RS11130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BEN74_RS11150	COG3023	N-Acetylmuramoyl-L-alanine amidase
BEN74_RS11160	COG5487	UPF0391 membrane protein
BEN74_RS11165	COG2983	Belongs to the UPF0260 family
BEN74_RS11170	COG5001	Diguanylate cyclase
BEN74_RS11175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BEN74_RS11190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BEN74_RS11200	COG2814	Major facilitator Superfamily
BEN74_RS11205	COG1335	isochorismatase
BEN74_RS11210	COG0385	Bile acid
BEN74_RS11225	COG0560	Phosphoserine phosphatase
BEN74_RS11225	COG3830	Belongs to the UPF0237 family
BEN74_RS11245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BEN74_RS11275	COG2733	membrane
BEN74_RS11290	COG2918	glutathione biosynthetic process
BEN74_RS11295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BEN74_RS11350	COG3706	GGDEF domain
BEN74_RS11355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BEN74_RS11375	COG0708	Exodeoxyribonuclease III
BEN74_RS11415	COG1454	alcohol dehydrogenase
BEN74_RS11420	COG1120	ATPase activity
BEN74_RS11425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEN74_RS11430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEN74_RS11435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEN74_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
BEN74_RS11455	COG1169	isochorismate synthase
BEN74_RS11460	COG1021	2,3-dihydroxybenzoate-AMP ligase
BEN74_RS11465	COG1535	isochorismatase
BEN74_RS11465	COG3433	isochorismatase activity
BEN74_RS11470	COG1535	isochorismatase
BEN74_RS11470	COG3433	isochorismatase activity
BEN74_RS11475	COG0019	diaminopimelate decarboxylase activity
BEN74_RS11480	COG1595	DNA-templated transcription, initiation
BEN74_RS11490	COG4773	Receptor
BEN74_RS11540	COG1192	Involved in chromosome partitioning
BEN74_RS11560	COG0586	Pfam SNARE associated Golgi protein
BEN74_RS11565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BEN74_RS11565	COG0519	Catalyzes the synthesis of GMP from XMP
BEN74_RS11620	COG0534	Mate efflux family protein
BEN74_RS11655	COG2814	Major facilitator Superfamily
BEN74_RS11660	COG0629	single-stranded DNA binding
BEN74_RS11725	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BEN74_RS11745	COG1335	isochorismatase
BEN74_RS11785	COG3158	transport of potassium into the cell
BEN74_RS11820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BEN74_RS11870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BEN74_RS11875	COG0131	Imidazoleglycerol-phosphate dehydratase
BEN74_RS11980	COG0322	excinuclease ABC activity
BEN74_RS11990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BEN74_RS12005	COG3275	phosphorelay sensor kinase activity
BEN74_RS12015	COG0181	hydroxymethylbilane synthase activity
BEN74_RS12060	COG1716	ATPase activity
BEN74_RS12065	COG0546	phosphoglycolate phosphatase activity
BEN74_RS12095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BEN74_RS12120	COG0081	regulation of translation
BEN74_RS12125	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BEN74_RS12130	COG0222	ribosome binding
BEN74_RS12135	COG0085	RNA polymerase activity
BEN74_RS12165	COG2056	Na+-H+ antiporter family
BEN74_RS12180	COG0326	Molecular chaperone. Has ATPase activity
BEN74_RS12210	COG0583	DNA-binding transcription factor activity
BEN74_RS12215	COG1280	lysine exporter protein (LysE YggA)
BEN74_RS12220	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BEN74_RS12240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEN74_RS12245	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS12250	COG1024	Enoyl-CoA hydratase
BEN74_RS12255	COG1024	Enoyl-CoA hydratase
BEN74_RS12260	COG0477	Major facilitator Superfamily
BEN74_RS12270	COG0427	acetyl-CoA hydrolase
BEN74_RS12310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BEN74_RS12340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BEN74_RS12345	COG1074	ATP-dependent DNA helicase activity
BEN74_RS12360	COG1185	polyribonucleotide nucleotidyltransferase activity
BEN74_RS12365	COG0598	Magnesium transport protein CorA
BEN74_RS12370	COG2841	Protein conserved in bacteria
BEN74_RS12375	COG0789	Transcriptional regulator
BEN74_RS12380	COG0484	heat shock protein binding
BEN74_RS12400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BEN74_RS12410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BEN74_RS12435	COG4535	Mg2 and Co2 transporter CorC
BEN74_RS12440	COG0425	Belongs to the sulfur carrier protein TusA family
BEN74_RS12455	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BEN74_RS12455	COG0644	oxidoreductase
BEN74_RS12465	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BEN74_RS12480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEN74_RS12485	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BEN74_RS12525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BEN74_RS12550	COG0751	glycine-tRNA ligase activity
BEN74_RS12555	COG0752	glycyl-tRNA synthetase alpha subunit
BEN74_RS12570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BEN74_RS12570	COG0517	IMP dehydrogenase activity
BEN74_RS12570	COG0617	tRNA 3'-terminal CCA addition
BEN74_RS12575	COG1983	PspC domain protein
BEN74_RS12600	COG0318	PFAM AMP-dependent synthetase and ligase
BEN74_RS12605	COG1530	ribonuclease E activity
BEN74_RS12610	COG0564	pseudouridine synthase activity
BEN74_RS12615	COG0546	phosphoglycolate phosphatase activity
BEN74_RS12620	COG3971	2-oxopent-4-enoate hydratase activity
BEN74_RS12625	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BEN74_RS12650	COG0583	DNA-binding transcription factor activity
BEN74_RS12655	COG4638	Rieske (2fe-2S)
BEN74_RS12675	COG3384	dioxygenase
BEN74_RS12680	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEN74_RS12685	COG0697	spore germination
BEN74_RS12715	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS12730	COG1280	lysine exporter protein (LysE YggA)
BEN74_RS12785	COG0513	Belongs to the DEAD box helicase family
BEN74_RS12790	COG1127	ABC transporter
BEN74_RS12795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BEN74_RS12815	COG0598	Magnesium transport protein CorA
BEN74_RS12825	COG0494	nUDIX hydrolase
BEN74_RS12830	COG1040	competence protein
BEN74_RS12835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BEN74_RS12850	COG2937	Belongs to the GPAT DAPAT family
BEN74_RS12855	COG1946	Acyl-CoA thioesterase
BEN74_RS12865	COG1301	dicarboxylic acid transport
BEN74_RS12880	COG1959	2 iron, 2 sulfur cluster binding
BEN74_RS12890	COG0433	COG0433 Predicted ATPase
BEN74_RS12905	COG0051	transcription antitermination factor activity, RNA binding
BEN74_RS12910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BEN74_RS12915	COG0088	Forms part of the polypeptide exit tunnel
BEN74_RS12930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BEN74_RS12975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BEN74_RS12980	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BEN74_RS12995	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BEN74_RS13035	COG0202	RNA polymerase activity
BEN74_RS13045	COG2072	flavoprotein involved in K transport
BEN74_RS13050	COG1960	acyl-CoA dehydrogenase activity
BEN74_RS13055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BEN74_RS13085	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BEN74_RS13090	COG0339	signal peptide processing
BEN74_RS13095	COG0557	exoribonuclease II activity
BEN74_RS13125	COG0179	Fumarylacetoacetate (FAA) hydrolase
BEN74_RS13135	COG4753	response regulator
BEN74_RS13135	COG2207	Transcriptional regulator
BEN74_RS13145	COG1295	ribonuclease BN
BEN74_RS13195	COG1702	phosphate starvation-inducible protein PhoH
BEN74_RS13200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BEN74_RS13205	COG1196	nuclear chromosome segregation
BEN74_RS13205	COG0741	lytic transglycosylase activity
BEN74_RS13205	COG0739	heme binding
BEN74_RS13230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BEN74_RS13250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BEN74_RS13250	COG2813	Specifically methylates the guanine in position
BEN74_RS13260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BEN74_RS13270	COG3128	pkhd-type hydroxylase
BEN74_RS13280	COG4774	siderophore transport
BEN74_RS13285	COG4771	TonB-dependent receptor
BEN74_RS13295	COG0740	serine-type endopeptidase activity
BEN74_RS13315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BEN74_RS13315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BEN74_RS13340	COG0857	belongs to the CobB CobQ family
BEN74_RS13340	COG0280	phosphate acetyltransferase
BEN74_RS13345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BEN74_RS13360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BEN74_RS13375	COG0793	Belongs to the peptidase S41A family
BEN74_RS13390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BEN74_RS13405	COG0084	hydrolase, TatD family'
BEN74_RS13435	COG2814	Major facilitator Superfamily
BEN74_RS13450	COG0697	spore germination
BEN74_RS13490	COG3622	Belongs to the hyi family
BEN74_RS13495	COG2084	Dehydrogenase
BEN74_RS13500	COG1024	Enoyl-CoA hydratase
BEN74_RS13525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BEN74_RS13545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BEN74_RS13555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BEN74_RS13570	COG2986	histidine ammonia-lyase
BEN74_RS13600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BEN74_RS13610	COG1028	Short-chain dehydrogenase reductase Sdr
BEN74_RS13615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BEN74_RS13625	COG0736	holo-[acyl-carrier-protein] synthase activity
BEN74_RS13640	COG1862	Preprotein translocase
BEN74_RS13650	COG1704	LemA family
BEN74_RS13660	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BEN74_RS13675	COG5002	protein histidine kinase activity
BEN74_RS13680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BEN74_RS13700	COG0726	polysaccharide deacetylase
BEN74_RS13730	COG1088	dTDP-glucose 4,6-dehydratase activity
BEN74_RS13735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BEN74_RS13750	COG1216	Glycosyl transferase, family 2
BEN74_RS13790	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BEN74_RS13820	COG2096	Adenosyltransferase
BEN74_RS13825	COG4206	TonB-dependent receptor
BEN74_RS13875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BEN74_RS13880	COG0285	dihydrofolate synthase activity
BEN74_RS13900	COG0450	alkyl hydroperoxide reductase
BEN74_RS13915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BEN74_RS13920	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BEN74_RS13945	COG2885	chlorophyll binding
BEN74_RS14015	COG2969	positive regulation of protein catabolic process
BEN74_RS14020	COG0625	glutathione transferase activity
BEN74_RS14025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BEN74_RS14030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BEN74_RS14035	COG2207	Transcriptional regulator
BEN74_RS14040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BEN74_RS14085	COG0183	Belongs to the thiolase family
BEN74_RS14095	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BEN74_RS14095	COG2885	chlorophyll binding
BEN74_RS14105	COG0833	amino acid
BEN74_RS14115	COG2233	PERMEase
BEN74_RS14120	COG1217	gtp-binding protein TYPA
BEN74_RS14125	COG1970	mechanosensitive ion channel activity
BEN74_RS14130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEN74_RS14145	COG4772	TonB-dependent receptor
BEN74_RS14150	COG1902	pentaerythritol trinitrate reductase activity
BEN74_RS14175	COG0354	folic acid binding
BEN74_RS14180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BEN74_RS14195	COG1487	ribonuclease activity
BEN74_RS14235	COG0564	pseudouridine synthase activity
BEN74_RS14260	COG3189	MarR family transcriptional regulator
BEN74_RS14270	COG2824	Alkylphosphonate utilization operon protein PhnA
BEN74_RS14280	COG3422	double-strand break repair
BEN74_RS14295	COG1051	belongs to the nudix hydrolase family
BEN74_RS14305	COG0352	thiamine-phosphate diphosphorylase activity
BEN74_RS14305	COG0351	phosphomethylpyrimidine kinase
BEN74_RS14305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BEN74_RS14320	COG0579	oxidoreductase
BEN74_RS14330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BEN74_RS14340	COG2801	Transposase and inactivated derivatives
BEN74_RS14355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BEN74_RS14360	COG3545	Serine hydrolase
BEN74_RS14375	COG0730	response to heat
BEN74_RS14385	COG1196	nuclear chromosome segregation
BEN74_RS14395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BEN74_RS14420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BEN74_RS14430	COG2267	carboxylic ester hydrolase activity
BEN74_RS14430	COG2226	methyltransferase
BEN74_RS14460	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BEN74_RS14465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BEN74_RS14475	COG0009	L-threonylcarbamoyladenylate synthase
BEN74_RS14480	COG3101	peptidyl-lysine hydroxylation
BEN74_RS14485	COG1399	metal-binding, possibly nucleic acid-binding protein
BEN74_RS14490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BEN74_RS14500	COG1028	Short-chain dehydrogenase reductase Sdr
BEN74_RS14525	COG0251	oxidation-reduction process
BEN74_RS14530	COG1113	amino acid transport
BEN74_RS14540	COG1981	membrane
BEN74_RS14555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BEN74_RS14580	COG0456	acetyltransferase
BEN74_RS14590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BEN74_RS14595	COG0492	ferredoxin-NADP+ reductase activity
BEN74_RS14600	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BEN74_RS14600	COG1674	ftsk spoiiie
BEN74_RS14610	COG0583	DNA-binding transcription factor activity
BEN74_RS14625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BEN74_RS14630	COG2894	cell division
BEN74_RS14635	COG0850	regulation of cytokinetic process
BEN74_RS14645	COG0204	Acyl-transferase
BEN74_RS14655	COG0210	DNA helicase
BEN74_RS14680	COG0121	glutamine amidotransferase
BEN74_RS14700	COG2914	Belongs to the UPF0125 (RnfH) family
BEN74_RS14710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BEN74_RS14715	COG0735	belongs to the Fur family
BEN74_RS14750	COG0420	3'-5' exonuclease activity
BEN74_RS14770	COG0702	epimerase
BEN74_RS14775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BEN74_RS14785	COG2050	protein possibly involved in aromatic compounds catabolism
BEN74_RS14790	COG1566	PFAM secretion protein HlyD family protein
BEN74_RS14795	COG2814	Major facilitator Superfamily
BEN74_RS14800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BEN74_RS14810	COG0582	viral genome integration into host DNA
BEN74_RS14895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BEN74_RS14925	COG3177	Filamentation induced by cAMP protein fic
BEN74_RS14940	COG0582	viral genome integration into host DNA
BEN74_RS15115	COG4521	taurine ABC transporter
BEN74_RS15120	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BEN74_RS15125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BEN74_RS15130	COG2175	clavaminate synthase activity
BEN74_RS15135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BEN74_RS15140	COG0235	Class ii aldolase
BEN74_RS15145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEN74_RS15155	COG3135	benzoate transporter
BEN74_RS15160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEN74_RS15175	COG2871	sodium ion transport
BEN74_RS15215	COG1696	Membrane protein involved in D-alanine export
BEN74_RS15235	COG2814	Major facilitator Superfamily
BEN74_RS15240	COG2030	dehydratase
BEN74_RS15240	COG1012	belongs to the aldehyde dehydrogenase family
BEN74_RS15245	COG3396	Phenylacetate-CoA oxygenase
BEN74_RS15250	COG3460	Phenylacetate-CoA oxygenase
BEN74_RS15255	COG3396	Phenylacetate-CoA oxygenase
BEN74_RS15260	COG2151	metal-sulfur cluster biosynthetic enzyme
BEN74_RS15265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEN74_RS15270	COG1024	Enoyl-CoA hydratase
BEN74_RS15275	COG1024	Enoyl-CoA hydratase
BEN74_RS15280	COG1250	3-hydroxyacyl-CoA dehydrogenase
BEN74_RS15285	COG0183	Belongs to the thiolase family
BEN74_RS15290	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BEN74_RS15295	COG3327	negative regulation of DNA-templated transcription, initiation
BEN74_RS15315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BEN74_RS15350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEN74_RS15360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEN74_RS15365	COG1077	Cell shape determining protein MreB Mrl
BEN74_RS15370	COG1792	Involved in formation and maintenance of cell shape
BEN74_RS15380	COG0424	maF-like protein
BEN74_RS15390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEN74_RS15425	COG3188	usher protein
BEN74_RS15440	COG0753	catalase activity
BEN74_RS15450	COG1113	amino acid transport
BEN74_RS15455	COG2828	Protein conserved in bacteria
BEN74_RS15460	COG3706	GGDEF domain
BEN74_RS15465	COG0142	geranyltranstransferase activity
BEN74_RS15470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEN74_RS15485	COG1752	Esterase of the alpha-beta hydrolase superfamily
BEN74_RS15495	COG2814	Major facilitator Superfamily
BEN74_RS15510	COG4771	TonB-dependent receptor
BEN74_RS15515	COG2194	sulfuric ester hydrolase activity
BEN74_RS15520	COG0745	RESPONSE REGULATOR receiver
BEN74_RS15525	COG0642	Histidine kinase
BEN74_RS15540	COG0004	ammonium transporteR
BEN74_RS15545	COG1126	abc transporter atp-binding protein
BEN74_RS15550	COG0765	amino acid transport
BEN74_RS15555	COG0765	amino acid transport
BEN74_RS15575	COG2852	Protein conserved in bacteria
BEN74_RS15585	COG0525	valine-tRNA ligase activity
BEN74_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
BEN74_RS15605	COG0393	Putative heavy-metal-binding
BEN74_RS15610	COG0393	Putative heavy-metal-binding
BEN74_RS15615	COG1538	Outer membrane efflux protein
BEN74_RS15625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN74_RS15630	COG0671	phosphoesterase, PA-phosphatase related
BEN74_RS15645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BEN74_RS15660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BEN74_RS15670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BEN74_RS15675	COG1648	precorrin-2 dehydrogenase activity
BEN74_RS15675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BEN74_RS15680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BEN74_RS15690	COG1733	regulation of RNA biosynthetic process
BEN74_RS15700	COG0531	amino acid
BEN74_RS15720	COG0321	lipoyl(octanoyl) transferase activity
BEN74_RS15750	COG0586	Pfam SNARE associated Golgi protein
BEN74_RS15770	COG1309	transcriptional regulator
BEN74_RS15780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BEN74_RS15805	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BEN74_RS15810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BEN74_RS15840	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BEN74_RS15855	COG0358	DNA primase activity
BEN74_RS15865	COG0564	pseudouridine synthase activity
BEN74_RS15895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BEN74_RS15925	COG0110	maltose O-acetyltransferase activity
BEN74_RS15945	COG0505	Belongs to the CarA family
BEN74_RS15965	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BEN74_RS15970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BEN74_RS15975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BEN74_RS16010	COG1253	flavin adenine dinucleotide binding
BEN74_RS16035	COG2239	Acts as a magnesium transporter
BEN74_RS16045	COG0501	Belongs to the peptidase M48B family
BEN74_RS16050	COG1196	nuclear chromosome segregation
BEN74_RS16050	COG0741	lytic transglycosylase activity
BEN74_RS16050	COG0739	heme binding
BEN74_RS16070	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BEN74_RS16075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BEN74_RS16120	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BEN74_RS16140	COG0281	malic enzyme
BEN74_RS16140	COG0280	phosphate acetyltransferase
BEN74_RS16145	COG5001	Diguanylate cyclase
BEN74_RS16145	COG3300	MHYT domain
BEN74_RS16150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BEN74_RS16155	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BEN74_RS16160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BEN74_RS16210	COG1113	amino acid transport
BEN74_RS16230	COG0019	diaminopimelate decarboxylase activity
BEN74_RS16245	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BEN74_RS16250	COG0693	protein deglycase activity
BEN74_RS16260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BEN74_RS16265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BEN74_RS16300	COG2252	PERMEase
BEN74_RS16305	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BEN74_RS16320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BEN74_RS16330	COG0527	aspartate kinase activity
BEN74_RS16350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BEN74_RS16365	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BEN74_RS16390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BEN74_RS16405	COG1047	Peptidyl-prolyl cis-trans
BEN74_RS16415	COG1686	Belongs to the peptidase S11 family
BEN74_RS16425	COG0436	Aminotransferase
BEN74_RS16430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BEN74_RS16435	COG0386	Belongs to the glutathione peroxidase family
BEN74_RS16455	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BEN74_RS16460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BEN74_RS16470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BEN74_RS16500	COG0012	GTP binding
BEN74_RS16505	COG2011	ABC-type metal ion transport system permease component
BEN74_RS16510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BEN74_RS16515	COG1464	Belongs to the NlpA lipoprotein family
BEN74_RS16520	COG1464	Belongs to the NlpA lipoprotein family
BEN74_RS16555	COG0204	Acyl-transferase
BEN74_RS16630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BEN74_RS16640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BEN74_RS16645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BEN74_RS16650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BEN74_RS16655	COG4977	sequence-specific DNA binding
BEN74_RS16655	COG1917	Cupin 2, conserved barrel domain protein
BEN74_RS16710	COG1061	Type III restriction enzyme res subunit
BEN74_RS16720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BEN74_RS16740	COG2963	transposase activity
BEN74_RS16750	COG4372	Transposase
BEN74_RS16800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BEN74_RS16825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BEN74_RS16845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BEN74_RS16860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BEN74_RS16880	COG4774	siderophore transport
BEN74_RS16945	COG3210	domain, Protein
BEN74_RS16955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BEN74_RS16960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEN74_RS16965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BEN74_RS16980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BEN74_RS16980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BEN74_RS17070	COG1643	Atp-dependent helicase
BEN74_RS17085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN74_RS17090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BEN74_RS17095	COG0583	DNA-binding transcription factor activity
BEN74_RS17110	COG2915	High frequency lysogenization protein hflD homolog
BEN74_RS17115	COG0482	sulfurtransferase activity
BEN74_RS17125	COG2130	NADP-dependent
BEN74_RS17130	COG1028	Short-chain dehydrogenase reductase Sdr
BEN74_RS17140	COG1846	Transcriptional regulator
BEN74_RS17150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BEN74_RS17155	COG1686	Belongs to the peptidase S11 family
BEN74_RS17180	COG0583	DNA-binding transcription factor activity
BEN74_RS17210	COG3323	Protein of unknown function (DUF1653)
BEN74_RS17210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BEN74_RS17215	COG0778	Nitroreductase
BEN74_RS17220	COG1024	Enoyl-CoA hydratase
BEN74_RS17225	COG1056	cytidyltransferase-related domain
BEN74_RS17225	COG1051	belongs to the nudix hydrolase family
BEN74_RS17235	COG0583	DNA-binding transcription factor activity
BEN74_RS17250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BEN74_RS17265	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BEN74_RS17270	COG0602	queuosine metabolic process
BEN74_RS17290	COG0583	DNA-binding transcription factor activity
BEN74_RS17295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BEN74_RS17300	COG4208	sulfate ABC transporter
BEN74_RS17315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BEN74_RS17325	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BEN74_RS17335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BEN74_RS17365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEN74_RS17380	COG0681	Belongs to the peptidase S26 family
BEN74_RS17390	COG0571	ribonuclease III activity
BEN74_RS17395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BEN74_RS17405	COG1381	Involved in DNA repair and RecF pathway recombination
BEN74_RS17410	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BEN74_RS17435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BEN74_RS17445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEN74_RS17470	COG3706	GGDEF domain
BEN74_RS17480	COG0556	nucleotide-excision repair
BEN74_RS17500	COG0702	epimerase
BEN74_RS17505	COG1733	regulation of RNA biosynthetic process
BEN74_RS17520	COG0671	phosphoesterase, PA-phosphatase related
BEN74_RS17530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BEN74_RS17535	COG0076	glutamate decarboxylase activity
BEN74_RS17545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BEN74_RS17550	COG0573	inorganic phosphate transmembrane transporter activity
BEN74_RS17560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BEN74_RS17570	COG0616	signal peptide processing
BEN74_RS17575	COG1012	belongs to the aldehyde dehydrogenase family
BEN74_RS17580	COG1765	OsmC-like protein
BEN74_RS17590	COG0667	Aldo Keto reductase
BEN74_RS17630	COG0540	Belongs to the ATCase OTCase family
BEN74_RS17665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BEN74_RS17685	COG0625	glutathione transferase activity
BEN74_RS17690	COG2249	NAD(P)H dehydrogenase (quinone) activity
BEN74_RS17720	COG2363	Small membrane protein
BEN74_RS17735	COG1278	Cold shock
BEN74_RS17740	COG0513	Belongs to the DEAD box helicase family
BEN74_RS17775	COG0167	dihydroorotate dehydrogenase activity
BEN74_RS17805	COG4783	chaperone-mediated protein folding
BEN74_RS17815	COG1610	YqeY-like protein
BEN74_RS17840	COG0515	serine threonine protein kinase
BEN74_RS17840	COG2815	serine threonine protein kinase
BEN74_RS17885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN74_RS17890	COG1823	symporter activity
BEN74_RS17900	COG0612	Peptidase, M16
BEN74_RS17915	COG3025	triphosphatase activity
BEN74_RS17930	COG0352	thiamine-phosphate diphosphorylase activity
BEN74_RS17955	COG1902	pentaerythritol trinitrate reductase activity
BEN74_RS17960	COG1073	alpha beta
BEN74_RS18090	COG2070	2-Nitropropane dioxygenase
BEN74_RS18100	COG2391	methyltransferase activity
BEN74_RS18125	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BEN74_RS18150	COG1280	lysine exporter protein (LysE YggA)
BEN74_RS18155	COG0519	Catalyzes the synthesis of GMP from XMP
BEN74_RS18155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BEN74_RS18180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BEN74_RS18180	COG1116	anion transmembrane transporter activity
BEN74_RS18190	COG2223	nitrite transmembrane transporter activity
BEN74_RS18195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN74_RS18195	COG2146	nitrite reductase [NAD(P)H] activity
BEN74_RS18200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN74_RS18205	COG0243	molybdopterin cofactor binding
BEN74_RS18215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BEN74_RS18230	COG0315	cyclic pyranopterin monophosphate synthase activity
BEN74_RS18230	COG0521	Mo-molybdopterin cofactor biosynthetic process
BEN74_RS18235	COG0303	'Molybdopterin
BEN74_RS18240	COG0725	ABC transporter, periplasmic molybdate-binding protein
BEN74_RS18245	COG4149	molybdate abc transporter
BEN74_RS18250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BEN74_RS18270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BEN74_RS18280	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BEN74_RS18285	COG1137	ATPase activity
BEN74_RS18300	COG0589	response to stress
BEN74_RS18305	COG4122	O-methyltransferase activity
BEN74_RS18315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BEN74_RS18325	COG3706	GGDEF domain
BEN74_RS18370	COG0138	bifunctional purine biosynthesis protein purh
BEN74_RS18375	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BEN74_RS18400	COG0445	tRNA wobble uridine modification
BEN74_RS18410	COG0268	Binds directly to 16S ribosomal RNA
BEN74_RS18415	COG0702	epimerase
BEN74_RS18420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BEN74_RS18435	COG4585	Histidine kinase
BEN74_RS18440	COG2850	peptidyl-arginine hydroxylation
BEN74_RS18445	COG4589	Belongs to the CDS family
BEN74_RS18460	COG0671	phosphoesterase, PA-phosphatase related
BEN74_RS18460	COG2453	phosphatase
BEN74_RS18465	COG2267	carboxylic ester hydrolase activity
BEN74_RS18470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BEN74_RS18475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BEN74_RS18500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BEN74_RS18515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BEN74_RS18520	COG0406	alpha-ribazole phosphatase activity
BEN74_RS18530	COG1346	cytolysis
BEN74_RS18540	COG0583	DNA-binding transcription factor activity
BEN74_RS18565	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BEN74_RS18585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BEN74_RS18605	COG0582	viral genome integration into host DNA
BEN74_RS18645	COG2199	diguanylate cyclase activity
BEN74_RS18645	COG2203	Gaf domain
BEN74_RS18680	COG0305	Participates in initiation and elongation during chromosome replication
BEN74_RS18865	COG1271	oxidase subunit
BEN74_RS18870	COG1294	oxidase, subunit
BEN74_RS18880	COG0697	spore germination
BEN74_RS18900	COG1285	pathogenesis
BEN74_RS18905	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN74_RS18915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEN74_RS18920	COG3781	membrane
BEN74_RS18940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BEN74_RS18945	COG0506	proline dehydrogenase activity
BEN74_RS18945	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BEN74_RS18945	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BEN74_RS18955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEN74_RS18960	COG1027	Aspartate ammonia-lyase
BEN74_RS18970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BEN74_RS19000	COG0316	Belongs to the HesB IscA family
BEN74_RS19005	COG0822	iron-sulfur transferase activity
BEN74_RS19015	COG1959	2 iron, 2 sulfur cluster binding
BEN74_RS19035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEN74_RS19060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BEN74_RS19085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BEN74_RS19090	COG0569	domain protein
BEN74_RS19115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BEN74_RS19120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BEN74_RS19145	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BEN74_RS19150	COG0542	response to heat