locus-tag	class	description
G0029_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G0029_RS00010	COG0592	DNA-directed DNA polymerase activity
G0029_RS00020	COG0187	DNA topoisomerase II activity
G0029_RS00030	COG0488	(ABC) transporter
G0029_RS00085	COG0657	acetylesterase activity
G0029_RS00095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G0029_RS00130	COG2814	Major facilitator Superfamily
G0029_RS00150	COG0693	protein deglycase activity
G0029_RS00155	COG2133	pyrroloquinoline quinone binding
G0029_RS00190	COG1047	Peptidyl-prolyl cis-trans
G0029_RS00200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G0029_RS00205	COG0196	riboflavin kinase activity
G0029_RS00225	COG1309	transcriptional regulator
G0029_RS00230	COG1116	anion transmembrane transporter activity
G0029_RS00235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G0029_RS00240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0029_RS00245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0029_RS00250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0029_RS00255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G0029_RS00255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G0029_RS00260	COG0675	Transposase, IS605 OrfB family
G0029_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS00290	COG0546	phosphoglycolate phosphatase activity
G0029_RS00295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G0029_RS00325	COG3023	N-Acetylmuramoyl-L-alanine amidase
G0029_RS00335	COG5487	UPF0391 membrane protein
G0029_RS00340	COG2983	Belongs to the UPF0260 family
G0029_RS00345	COG1683	Conserved Protein
G0029_RS00355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G0029_RS00360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G0029_RS00370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G0029_RS00375	COG2814	Major facilitator Superfamily
G0029_RS00385	COG1335	isochorismatase
G0029_RS00390	COG0385	Bile acid
G0029_RS00405	COG3830	Belongs to the UPF0237 family
G0029_RS00405	COG0560	Phosphoserine phosphatase
G0029_RS00425	COG0753	catalase activity
G0029_RS00470	COG2733	membrane
G0029_RS00485	COG2918	glutathione biosynthetic process
G0029_RS00490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G0029_RS00500	COG3150	esterase
G0029_RS00575	COG3706	GGDEF domain
G0029_RS00580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G0029_RS00595	COG1393	Belongs to the ArsC family
G0029_RS00600	COG0708	Exodeoxyribonuclease III
G0029_RS00625	COG3706	GGDEF domain
G0029_RS00630	COG0189	ligase activity
G0029_RS00640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0029_RS00650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G0029_RS00660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G0029_RS00695	COG2119	membrane
G0029_RS00700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0029_RS00700	COG0426	domain, Protein
G0029_RS00725	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G0029_RS00750	COG1902	pentaerythritol trinitrate reductase activity
G0029_RS00755	COG1519	Transferase
G0029_RS00760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0029_RS00765	COG0668	transmembrane transport
G0029_RS00775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G0029_RS00785	COG0307	riboflavin synthase, alpha
G0029_RS00795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0029_RS00800	COG0431	NADPH-dependent FMN reductase
G0029_RS00815	COG2205	protein histidine kinase activity
G0029_RS00815	COG0784	Response regulator, receiver
G0029_RS00820	COG3162	membrane
G0029_RS00885	COG0351	phosphomethylpyrimidine kinase
G0029_RS00885	COG0352	thiamine-phosphate diphosphorylase activity
G0029_RS00885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0029_RS00895	COG2814	Major facilitator Superfamily
G0029_RS00900	COG0629	single-stranded DNA binding
G0029_RS00910	COG0583	DNA-binding transcription factor activity
G0029_RS00915	COG1335	isochorismatase
G0029_RS00925	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G0029_RS00965	COG3158	transport of potassium into the cell
G0029_RS00985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G0029_RS01005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G0029_RS01010	COG1278	Cold shock
G0029_RS01020	COG0697	spore germination
G0029_RS01040	COG3152	Membrane
G0029_RS01050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G0029_RS01085	COG2226	methyltransferase
G0029_RS01105	COG3706	GGDEF domain
G0029_RS01135	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0029_RS01135	COG1024	Enoyl-CoA hydratase
G0029_RS01150	COG3706	GGDEF domain
G0029_RS01175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G0029_RS01190	COG3275	phosphorelay sensor kinase activity
G0029_RS01200	COG0181	hydroxymethylbilane synthase activity
G0029_RS01250	COG0546	phosphoglycolate phosphatase activity
G0029_RS01290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G0029_RS01305	COG0081	regulation of translation
G0029_RS01310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G0029_RS01320	COG0085	RNA polymerase activity
G0029_RS01325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G0029_RS01350	COG2056	Na+-H+ antiporter family
G0029_RS01355	COG3047	cAMP biosynthetic process
G0029_RS01365	COG0326	Molecular chaperone. Has ATPase activity
G0029_RS01405	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G0029_RS01415	COG0427	acetyl-CoA hydrolase
G0029_RS01455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0029_RS01485	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G0029_RS01490	COG1074	ATP-dependent DNA helicase activity
G0029_RS01495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0029_RS01510	COG0598	Magnesium transport protein CorA
G0029_RS01520	COG2841	Protein conserved in bacteria
G0029_RS01525	COG0789	Transcriptional regulator
G0029_RS01550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G0029_RS01560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G0029_RS01585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G0029_RS01590	COG4535	Mg2 and Co2 transporter CorC
G0029_RS01595	COG0425	Belongs to the sulfur carrier protein TusA family
G0029_RS01620	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G0029_RS01620	COG0644	oxidoreductase
G0029_RS01630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G0029_RS01645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G0029_RS01650	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G0029_RS01660	COG0493	'glutamate synthase
G0029_RS01690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G0029_RS01730	COG0751	glycine-tRNA ligase activity
G0029_RS01735	COG0752	glycyl-tRNA synthetase alpha subunit
G0029_RS01745	COG0617	tRNA 3'-terminal CCA addition
G0029_RS01745	COG0517	IMP dehydrogenase activity
G0029_RS01745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G0029_RS01750	COG1983	PspC domain protein
G0029_RS01780	COG0318	PFAM AMP-dependent synthetase and ligase
G0029_RS01785	COG1530	ribonuclease E activity
G0029_RS01800	COG3971	2-oxopent-4-enoate hydratase activity
G0029_RS01805	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G0029_RS01810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G0029_RS01825	COG0583	DNA-binding transcription factor activity
G0029_RS01830	COG4638	Rieske (2fe-2S)
G0029_RS01845	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS01850	COG3384	dioxygenase
G0029_RS01855	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0029_RS01875	COG0753	catalase activity
G0029_RS01890	COG1960	acyl-CoA dehydrogenase activity
G0029_RS01905	COG0494	nUDIX hydrolase
G0029_RS01925	COG0583	DNA-binding transcription factor activity
G0029_RS01940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G0029_RS01955	COG0473	3-isopropylmalate dehydrogenase activity
G0029_RS01985	COG0252	asparaginase activity
G0029_RS02020	COG1560	Kdo2-lipid A biosynthetic process
G0029_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS02030	COG0488	(ABC) transporter
G0029_RS02035	COG2900	Belongs to the SlyX family
G0029_RS02070	COG1929	Belongs to the glycerate kinase type-1 family
G0029_RS02080	COG0210	DNA helicase
G0029_RS02110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G0029_RS02110	COG4651	solute:proton antiporter activity
G0029_RS02135	COG0788	formyltetrahydrofolate deformylase activity
G0029_RS02175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G0029_RS02245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0029_RS02245	COG2813	Specifically methylates the guanine in position
G0029_RS02255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G0029_RS02270	COG4774	siderophore transport
G0029_RS02275	COG4771	TonB-dependent receptor
G0029_RS02285	COG0740	serine-type endopeptidase activity
G0029_RS02310	COG3540	Alkaline phosphatase
G0029_RS02320	COG0857	belongs to the CobB CobQ family
G0029_RS02320	COG0280	phosphate acetyltransferase
G0029_RS02325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G0029_RS02335	COG2267	carboxylic ester hydrolase activity
G0029_RS02350	COG0793	Belongs to the peptidase S41A family
G0029_RS02360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G0029_RS02375	COG0084	hydrolase, TatD family'
G0029_RS02385	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G0029_RS02400	COG1162	GTPase activity
G0029_RS02405	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G0029_RS02415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G0029_RS02440	COG1538	Outer membrane efflux protein
G0029_RS02445	COG0577	efflux transmembrane transporter activity
G0029_RS02445	COG1136	(ABC) transporter
G0029_RS02450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0029_RS02475	COG0028	Belongs to the TPP enzyme family
G0029_RS02480	COG0440	acetolactate synthase activity
G0029_RS02485	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G0029_RS02550	COG1426	Protein conserved in bacteria
G0029_RS02570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0029_RS02600	COG3956	TIGRFAM MazG family protein
G0029_RS02605	COG1596	polysaccharide export
G0029_RS02605	COG1555	photosystem II stabilization
G0029_RS02610	COG0617	tRNA 3'-terminal CCA addition
G0029_RS02615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G0029_RS02630	COG1660	Displays ATPase and GTPase activities
G0029_RS02635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G0029_RS02640	COG3028	Belongs to the UPF0307 family
G0029_RS02645	COG0318	PFAM AMP-dependent synthetase and ligase
G0029_RS02660	COG0069	glutamate synthase activity
G0029_RS02670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G0029_RS02680	COG0625	glutathione transferase activity
G0029_RS02695	COG1238	metal cluster binding
G0029_RS02750	COG0072	phenylalanine-tRNA ligase activity
G0029_RS02775	COG0248	Ppx GppA phosphatase
G0029_RS02785	COG0037	tRNA processing
G0029_RS02800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G0029_RS02800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G0029_RS02835	COG1764	response to oxidative stress
G0029_RS02840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0029_RS02905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G0029_RS02910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G0029_RS02970	COG1214	PFAM Peptidase M22, glycoprotease
G0029_RS02975	COG1968	undecaprenyl-diphosphatase activity
G0029_RS02995	COG4269	membrane
G0029_RS03010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G0029_RS03020	COG2132	Multicopper oxidase
G0029_RS03030	COG2076	Multidrug Resistance protein
G0029_RS03055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G0029_RS03060	COG1278	Cold shock
G0029_RS03070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G0029_RS03075	COG4115	mRNA cleavage
G0029_RS03080	COG2161	toxin-antitoxin pair type II binding
G0029_RS03090	COG3545	Serine hydrolase
G0029_RS03105	COG0730	response to heat
G0029_RS03115	COG1196	nuclear chromosome segregation
G0029_RS03125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G0029_RS03130	COG0833	amino acid
G0029_RS03140	COG2233	PERMEase
G0029_RS03145	COG1217	gtp-binding protein TYPA
G0029_RS03155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0029_RS03165	COG3659	wide pore channel activity
G0029_RS03170	COG4772	TonB-dependent receptor
G0029_RS03175	COG1902	pentaerythritol trinitrate reductase activity
G0029_RS03205	COG0354	folic acid binding
G0029_RS03210	COG2132	Multicopper oxidase
G0029_RS03210	COG2132	Multicopper oxidase
G0029_RS03260	COG0564	pseudouridine synthase activity
G0029_RS03280	COG3189	MarR family transcriptional regulator
G0029_RS03285	COG2824	Alkylphosphonate utilization operon protein PhnA
G0029_RS03310	COG0628	permease
G0029_RS03315	COG5342	invasion associated locus B
G0029_RS03320	COG0351	phosphomethylpyrimidine kinase
G0029_RS03320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0029_RS03320	COG0352	thiamine-phosphate diphosphorylase activity
G0029_RS03365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G0029_RS03370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G0029_RS03370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G0029_RS03375	COG0745	RESPONSE REGULATOR receiver
G0029_RS03380	COG2205	protein histidine kinase activity
G0029_RS03390	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0029_RS03400	COG0649	NAD binding
G0029_RS03400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0029_RS03410	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G0029_RS03425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0029_RS03435	COG0713	ATP synthesis coupled electron transport
G0029_RS03440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0029_RS03445	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0029_RS03455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G0029_RS03465	COG1278	Cold shock
G0029_RS03470	COG0583	DNA-binding transcription factor activity
G0029_RS03480	COG1126	abc transporter atp-binding protein
G0029_RS03485	COG0765	amino acid transport
G0029_RS03490	COG0765	amino acid transport
G0029_RS03510	COG0668	transmembrane transport
G0029_RS03525	COG2081	HI0933 family
G0029_RS03575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0029_RS03575	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0029_RS03595	COG0489	protein tyrosine kinase activity
G0029_RS03610	COG2358	TRAP transporter, solute receptor (TAXI family
G0029_RS03645	COG0442	prolyl-tRNA aminoacylation
G0029_RS03680	COG0840	transmembrane signaling receptor activity
G0029_RS03685	COG0643	Histidine kinase
G0029_RS03685	COG2198	Histidine kinase
G0029_RS03710	COG2832	Protein of unknown function (DUF454)
G0029_RS03770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G0029_RS03780	COG1289	transmembrane transporter activity
G0029_RS03785	COG2814	Major facilitator Superfamily
G0029_RS03795	COG0786	glutamate:sodium symporter activity
G0029_RS03800	COG1115	amino acid carrier protein
G0029_RS03805	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0029_RS03815	COG1607	acyl-coa hydrolase
G0029_RS03825	COG2814	Major facilitator Superfamily
G0029_RS03830	COG0583	DNA-binding transcription factor activity
G0029_RS03860	COG0523	cobalamin synthesis protein
G0029_RS03865	COG4681	YaeQ
G0029_RS03875	COG2199	diguanylate cyclase activity
G0029_RS03875	COG2203	Gaf domain
G0029_RS03900	COG1024	Enoyl-CoA hydratase
G0029_RS03925	COG0477	Major facilitator Superfamily
G0029_RS03930	COG0242	peptide deformylase activity
G0029_RS03945	COG2066	Belongs to the glutaminase family
G0029_RS03955	COG2852	Protein conserved in bacteria
G0029_RS03970	COG0525	valine-tRNA ligase activity
G0029_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS03995	COG0393	Putative heavy-metal-binding
G0029_RS04000	COG1538	Outer membrane efflux protein
G0029_RS04010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0029_RS04015	COG0671	phosphoesterase, PA-phosphatase related
G0029_RS04030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G0029_RS04035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G0029_RS04055	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G0029_RS04065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G0029_RS04070	COG1648	precorrin-2 dehydrogenase activity
G0029_RS04070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G0029_RS04075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G0029_RS04110	COG0531	amino acid
G0029_RS04125	COG0321	lipoyl(octanoyl) transferase activity
G0029_RS04135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G0029_RS04160	COG0586	Pfam SNARE associated Golgi protein
G0029_RS04185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G0029_RS04210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G0029_RS04215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G0029_RS04245	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G0029_RS04260	COG0358	DNA primase activity
G0029_RS04270	COG0564	pseudouridine synthase activity
G0029_RS04300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0029_RS04325	COG0110	maltose O-acetyltransferase activity
G0029_RS04330	COG0251	oxidation-reduction process
G0029_RS04335	COG1309	transcriptional regulator
G0029_RS04345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G0029_RS04350	COG0505	Belongs to the CarA family
G0029_RS04375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0029_RS04380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G0029_RS04410	COG2851	Citrate transporter
G0029_RS04420	COG1253	flavin adenine dinucleotide binding
G0029_RS04445	COG0584	glycerophosphoryl diester phosphodiesterase
G0029_RS04455	COG2239	Acts as a magnesium transporter
G0029_RS04470	COG1196	nuclear chromosome segregation
G0029_RS04470	COG0739	heme binding
G0029_RS04470	COG0741	lytic transglycosylase activity
G0029_RS04475	COG0037	tRNA processing
G0029_RS04485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G0029_RS04490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0029_RS04505	COG0235	Class ii aldolase
G0029_RS04515	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G0029_RS04530	COG0280	phosphate acetyltransferase
G0029_RS04530	COG0281	malic enzyme
G0029_RS04540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0029_RS04545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G0029_RS04550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G0029_RS04575	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G0029_RS04610	COG1115	amino acid carrier protein
G0029_RS04615	COG1113	amino acid transport
G0029_RS04625	COG0019	diaminopimelate decarboxylase activity
G0029_RS04640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G0029_RS04650	COG1522	sequence-specific DNA binding
G0029_RS04655	COG1280	lysine exporter protein (LysE YggA)
G0029_RS04685	COG1301	dicarboxylic acid transport
G0029_RS04690	COG3293	Transposase
G0029_RS04710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0029_RS04730	COG1671	Belongs to the UPF0178 family
G0029_RS04735	COG0697	spore germination
G0029_RS04750	COG1136	(ABC) transporter
G0029_RS04755	COG2333	competence protein COMEC
G0029_RS04755	COG0658	competence protein
G0029_RS04780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G0029_RS04785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G0029_RS04790	COG0628	permease
G0029_RS04825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0029_RS04845	COG0823	Involved in the tonB-independent uptake of proteins
G0029_RS04865	COG0824	Thioesterase
G0029_RS04875	COG2255	four-way junction helicase activity
G0029_RS04895	COG0047	phosphoribosylformylglycinamidine synthase activity
G0029_RS04895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G0029_RS04910	COG0583	DNA-binding transcription factor activity
G0029_RS04915	COG3323	Protein of unknown function (DUF1653)
G0029_RS04915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G0029_RS04920	COG0778	Nitroreductase
G0029_RS04925	COG1024	Enoyl-CoA hydratase
G0029_RS04930	COG1056	cytidyltransferase-related domain
G0029_RS04930	COG1051	belongs to the nudix hydrolase family
G0029_RS04935	COG2353	YceI-like domain
G0029_RS04940	COG0583	DNA-binding transcription factor activity
G0029_RS04950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G0029_RS04960	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G0029_RS04965	COG0602	queuosine metabolic process
G0029_RS04985	COG0583	DNA-binding transcription factor activity
G0029_RS04990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G0029_RS04995	COG4208	sulfate ABC transporter
G0029_RS05010	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0029_RS05015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0029_RS05020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G0029_RS05025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G0029_RS05030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G0029_RS05055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G0029_RS05070	COG0681	Belongs to the peptidase S26 family
G0029_RS05080	COG0571	ribonuclease III activity
G0029_RS05085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G0029_RS05095	COG1381	Involved in DNA repair and RecF pathway recombination
G0029_RS05100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G0029_RS05135	COG0436	Aminotransferase
G0029_RS05145	COG0052	Belongs to the universal ribosomal protein uS2 family
G0029_RS05170	COG2951	lytic endotransglycosylase activity
G0029_RS05185	COG0842	Transport permease protein
G0029_RS05190	COG1131	(ABC) transporter
G0029_RS05200	COG0582	viral genome integration into host DNA
G0029_RS05240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G0029_RS05425	COG3293	Transposase
G0029_RS05455	COG1741	Belongs to the pirin family
G0029_RS05470	COG3739	integral membrane protein
G0029_RS05485	COG3706	GGDEF domain
G0029_RS05505	COG0302	gtp cyclohydrolase
G0029_RS05525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G0029_RS05530	COG0512	Glutamine amidotransferase of anthranilate synthase
G0029_RS05535	COG0174	glutamine synthetase
G0029_RS05550	COG3161	chorismate lyase activity
G0029_RS05555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G0029_RS05595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G0029_RS05605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G0029_RS05620	COG1960	acyl-CoA dehydrogenase activity
G0029_RS05625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G0029_RS05635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G0029_RS05660	COG2175	clavaminate synthase activity
G0029_RS05680	COG2199	diguanylate cyclase activity
G0029_RS05690	COG0556	nucleotide-excision repair
G0029_RS05725	COG0702	epimerase
G0029_RS05730	COG1733	regulation of RNA biosynthetic process
G0029_RS05750	COG0431	NADPH-dependent FMN reductase
G0029_RS05755	COG0798	PFAM Bile acid sodium symporter
G0029_RS05765	COG0640	Transcriptional regulator
G0029_RS05770	COG4772	TonB-dependent receptor
G0029_RS05780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G0029_RS05785	COG0076	glutamate decarboxylase activity
G0029_RS05795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G0029_RS05800	COG0573	inorganic phosphate transmembrane transporter activity
G0029_RS05810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G0029_RS05815	COG0616	signal peptide processing
G0029_RS05845	COG0482	sulfurtransferase activity
G0029_RS05855	COG3293	Transposase
G0029_RS05865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G0029_RS05870	COG1686	Belongs to the peptidase S11 family
G0029_RS05895	COG0583	DNA-binding transcription factor activity
G0029_RS05900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G0029_RS05905	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G0029_RS05910	COG1067	ATP-dependent peptidase activity
G0029_RS05960	COG1966	Carbon starvation protein
G0029_RS05965	COG2879	small protein
G0029_RS05970	COG0714	Associated with various cellular activities
G0029_RS05990	COG3293	Transposase
G0029_RS05995	COG1765	OsmC-like protein
G0029_RS06005	COG0667	Aldo Keto reductase
G0029_RS06010	COG0542	response to heat
G0029_RS06050	COG0540	Belongs to the ATCase OTCase family
G0029_RS06070	COG0589	response to stress
G0029_RS06075	COG0589	response to stress
G0029_RS06085	COG2076	Multidrug Resistance protein
G0029_RS06090	COG1309	transcriptional regulator
G0029_RS06095	COG3135	benzoate transporter
G0029_RS06105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G0029_RS06110	COG0583	DNA-binding transcription factor activity
G0029_RS06125	COG0183	Belongs to the thiolase family
G0029_RS06130	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS06140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G0029_RS06150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G0029_RS06155	COG0824	Thioesterase
G0029_RS06160	COG1454	alcohol dehydrogenase
G0029_RS06165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G0029_RS06185	COG0069	glutamate synthase activity
G0029_RS06200	COG2308	Evidence 4 Homologs of previously reported genes of
G0029_RS06210	COG1305	Transglutaminase-like
G0029_RS06220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G0029_RS06225	COG0305	Participates in initiation and elongation during chromosome replication
G0029_RS06240	COG0360	Binds together with S18 to 16S ribosomal RNA
G0029_RS06260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G0029_RS06265	COG1845	cytochrome c oxidase, subunit III
G0029_RS06270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G0029_RS06275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G0029_RS06300	COG4682	membrane
G0029_RS06305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0029_RS06325	COG2890	protein-(glutamine-N5) methyltransferase activity
G0029_RS06330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G0029_RS06345	COG2207	Transcriptional regulator
G0029_RS06355	COG1960	acyl-CoA dehydrogenase activity
G0029_RS06360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G0029_RS06370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G0029_RS06380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G0029_RS06405	COG0477	Major facilitator Superfamily
G0029_RS06410	COG0729	surface antigen
G0029_RS06595	COG5410	chromosome segregation
G0029_RS06690	COG3293	Transposase
G0029_RS06785	COG1570	exodeoxyribonuclease VII activity
G0029_RS06790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0029_RS06830	COG0786	glutamate:sodium symporter activity
G0029_RS06870	COG1114	Component of the transport system for branched-chain amino acids
G0029_RS06875	COG0024	Methionine aminopeptidase
G0029_RS06880	COG0583	DNA-binding transcription factor activity
G0029_RS06885	COG0583	DNA-binding transcription factor activity
G0029_RS06890	COG2267	carboxylic ester hydrolase activity
G0029_RS06900	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0029_RS06900	COG1902	pentaerythritol trinitrate reductase activity
G0029_RS06915	COG2814	Major facilitator Superfamily
G0029_RS06925	COG0583	DNA-binding transcription factor activity
G0029_RS06945	COG0148	phosphopyruvate hydratase activity
G0029_RS06960	COG0772	Belongs to the SEDS family
G0029_RS06975	COG4890	Cyd operon protein YbgT
G0029_RS06980	COG1294	oxidase, subunit
G0029_RS07030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G0029_RS07050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0029_RS07065	COG0133	tryptophan synthase activity
G0029_RS07075	COG0517	IMP dehydrogenase activity
G0029_RS07075	COG0516	GMP reductase activity
G0029_RS07105	COG0612	Peptidase, M16
G0029_RS07110	COG0552	protein localization to endoplasmic reticulum
G0029_RS07190	COG1960	acyl-CoA dehydrogenase activity
G0029_RS07255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0029_RS07260	COG0730	response to heat
G0029_RS07265	COG0745	RESPONSE REGULATOR receiver
G0029_RS07265	COG3292	Two component regulator propeller
G0029_RS07265	COG2205	protein histidine kinase activity
G0029_RS07270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0029_RS07275	COG2207	Transcriptional regulator
G0029_RS07280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G0029_RS07285	COG4589	Belongs to the CDS family
G0029_RS07300	COG2453	phosphatase
G0029_RS07300	COG0671	phosphoesterase, PA-phosphatase related
G0029_RS07305	COG2267	carboxylic ester hydrolase activity
G0029_RS07310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G0029_RS07315	COG1946	Acyl-CoA thioesterase
G0029_RS07360	COG2223	nitrite transmembrane transporter activity
G0029_RS07375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G0029_RS07390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G0029_RS07415	COG0583	DNA-binding transcription factor activity
G0029_RS07440	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G0029_RS07445	COG0671	phosphoesterase, PA-phosphatase related
G0029_RS07450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0029_RS07470	COG1960	acyl-CoA dehydrogenase activity
G0029_RS07475	COG2207	Transcriptional regulator
G0029_RS07480	COG2814	Major facilitator Superfamily
G0029_RS07490	COG3152	Membrane
G0029_RS07505	COG1960	acyl-CoA dehydrogenase activity
G0029_RS07555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0029_RS07565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G0029_RS07565	COG1017	nitric oxide dioxygenase activity
G0029_RS07575	COG0488	(ABC) transporter
G0029_RS07580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0029_RS07590	COG0509	glycine decarboxylation via glycine cleavage system
G0029_RS07605	COG1132	(ABC) transporter
G0029_RS07610	COG3706	GGDEF domain
G0029_RS07615	COG0668	transmembrane transport
G0029_RS07620	COG3122	Protein conserved in bacteria
G0029_RS07645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G0029_RS07655	COG0789	Transcriptional regulator
G0029_RS07670	COG1960	acyl-CoA dehydrogenase activity
G0029_RS07675	COG0183	Belongs to the thiolase family
G0029_RS07680	COG0427	acetyl-CoA hydrolase
G0029_RS07685	COG0546	phosphoglycolate phosphatase activity
G0029_RS07695	COG4521	taurine ABC transporter
G0029_RS07700	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G0029_RS07705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G0029_RS07710	COG2175	clavaminate synthase activity
G0029_RS07725	COG0439	Biotin carboxylase
G0029_RS07730	COG1196	nuclear chromosome segregation
G0029_RS07750	COG0864	Transcriptional regulator
G0029_RS07760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G0029_RS07775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G0029_RS07780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0029_RS07785	COG0730	response to heat
G0029_RS07810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G0029_RS07815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G0029_RS07825	COG1960	acyl-CoA dehydrogenase activity
G0029_RS07830	COG2814	Major facilitator Superfamily
G0029_RS07840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0029_RS07845	COG0183	Belongs to the thiolase family
G0029_RS07850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0029_RS07855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0029_RS07860	COG4829	muconolactone delta-isomerase
G0029_RS07865	COG4948	Mandelate Racemase Muconate Lactonizing
G0029_RS07870	COG0583	DNA-binding transcription factor activity
G0029_RS07875	COG1116	anion transmembrane transporter activity
G0029_RS07875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0029_RS07880	COG0745	RESPONSE REGULATOR receiver
G0029_RS07885	COG2223	nitrite transmembrane transporter activity
G0029_RS07890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0029_RS07895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0029_RS07900	COG0243	molybdopterin cofactor binding
G0029_RS07910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G0029_RS07920	COG0314	molybdopterin synthase activity
G0029_RS07925	COG0521	Mo-molybdopterin cofactor biosynthetic process
G0029_RS07925	COG0315	cyclic pyranopterin monophosphate synthase activity
G0029_RS07930	COG0303	'Molybdopterin
G0029_RS07935	COG0725	ABC transporter, periplasmic molybdate-binding protein
G0029_RS07940	COG4149	molybdate abc transporter
G0029_RS07945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G0029_RS07970	COG4628	conserved protein (DUF2132)
G0029_RS07975	COG0477	Major facilitator Superfamily
G0029_RS07980	COG2030	dehydratase
G0029_RS07980	COG1012	belongs to the aldehyde dehydrogenase family
G0029_RS07985	COG3396	Phenylacetate-CoA oxygenase
G0029_RS07990	COG3460	Phenylacetate-CoA oxygenase
G0029_RS07995	COG3396	Phenylacetate-CoA oxygenase
G0029_RS08000	COG2151	metal-sulfur cluster biosynthetic enzyme
G0029_RS08005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G0029_RS08010	COG1024	Enoyl-CoA hydratase
G0029_RS08015	COG1024	Enoyl-CoA hydratase
G0029_RS08020	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0029_RS08025	COG0183	Belongs to the thiolase family
G0029_RS08030	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G0029_RS08035	COG3327	negative regulation of DNA-templated transcription, initiation
G0029_RS08050	COG1968	undecaprenyl-diphosphatase activity
G0029_RS08065	COG3293	Transposase
G0029_RS08165	COG0477	Major facilitator Superfamily
G0029_RS08175	COG1024	Enoyl-CoA hydratase
G0029_RS08180	COG1960	acyl-CoA dehydrogenase activity
G0029_RS08185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G0029_RS08200	COG0583	DNA-binding transcription factor activity
G0029_RS08215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G0029_RS08235	COG2814	Major facilitator Superfamily
G0029_RS08240	COG0583	DNA-binding transcription factor activity
G0029_RS08250	COG4638	Rieske (2fe-2S)
G0029_RS08255	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G0029_RS08260	COG0633	Ferredoxin
G0029_RS08260	COG0543	2 iron, 2 sulfur cluster binding
G0029_RS08265	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS08270	COG3135	benzoate transporter
G0029_RS08275	COG0583	DNA-binding transcription factor activity
G0029_RS08300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0029_RS08305	COG4266	Belongs to the allantoicase family
G0029_RS08315	COG2233	PERMEase
G0029_RS08320	COG2351	hydroxyisourate hydrolase activity
G0029_RS08345	COG0697	spore germination
G0029_RS08360	COG0318	PFAM AMP-dependent synthetase and ligase
G0029_RS08450	COG0596	Alpha beta hydrolase
G0029_RS08500	COG0439	Biotin carboxylase
G0029_RS08510	COG3706	GGDEF domain
G0029_RS08515	COG2814	Major facilitator Superfamily
G0029_RS08525	COG1546	Belongs to the CinA family
G0029_RS08525	COG1058	Belongs to the CinA family
G0029_RS08540	COG2323	membrane
G0029_RS08590	COG1278	Cold shock
G0029_RS08600	COG1278	Cold shock
G0029_RS08625	COG0372	Belongs to the citrate synthase family
G0029_RS08655	COG0542	response to heat
G0029_RS08660	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G0029_RS08685	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G0029_RS08690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G0029_RS08700	COG0569	domain protein
G0029_RS08705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G0029_RS08730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G0029_RS08740	COG1585	Membrane protein implicated in regulation of membrane protease activity
G0029_RS08765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0029_RS08795	COG0822	iron-sulfur transferase activity
G0029_RS08800	COG0316	Belongs to the HesB IscA family
G0029_RS08830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G0029_RS08840	COG1027	Aspartate ammonia-lyase
G0029_RS08845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0029_RS08855	COG0506	proline dehydrogenase activity
G0029_RS08855	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0029_RS08855	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0029_RS08875	COG3698	Phosphodiester glycosidase
G0029_RS08890	COG0667	Aldo Keto reductase
G0029_RS08895	COG0583	DNA-binding transcription factor activity
G0029_RS08900	COG3781	membrane
G0029_RS08955	COG0697	spore germination
G0029_RS08970	COG0126	phosphoglycerate kinase activity
G0029_RS08980	COG0424	maF-like protein
G0029_RS08990	COG2850	peptidyl-arginine hydroxylation
G0029_RS09000	COG4585	Histidine kinase
G0029_RS09005	COG2197	response regulator
G0029_RS09015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G0029_RS09050	COG1011	Hydrolase
G0029_RS09055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G0029_RS09065	COG2137	regulation of response to DNA damage stimulus
G0029_RS09080	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0029_RS09090	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0029_RS09100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0029_RS09115	COG0575	Belongs to the CDS family
G0029_RS09120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G0029_RS09140	COG3852	Histidine kinase
G0029_RS09155	COG2814	Major facilitator Superfamily
G0029_RS09190	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G0029_RS09195	COG0138	bifunctional purine biosynthesis protein purh
G0029_RS09220	COG1464	Belongs to the NlpA lipoprotein family
G0029_RS09225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G0029_RS09230	COG2011	ABC-type metal ion transport system permease component
G0029_RS09275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G0029_RS09285	COG4122	O-methyltransferase activity
G0029_RS09320	COG1137	ATPase activity
G0029_RS09325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G0029_RS09335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G0029_RS09340	COG0517	IMP dehydrogenase activity
G0029_RS09340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G0029_RS09365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0029_RS09365	COG0519	Catalyzes the synthesis of GMP from XMP
G0029_RS09370	COG1280	lysine exporter protein (LysE YggA)
G0029_RS09395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G0029_RS09405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G0029_RS09425	COG2391	methyltransferase activity
G0029_RS09565	COG0352	thiamine-phosphate diphosphorylase activity
G0029_RS09585	COG1309	transcriptional regulator
G0029_RS09610	COG0612	Peptidase, M16
G0029_RS09620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0029_RS09625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G0029_RS09675	COG0154	amidase activity
G0029_RS09680	COG0477	Major facilitator Superfamily
G0029_RS09685	COG1522	sequence-specific DNA binding
G0029_RS09700	COG1610	YqeY-like protein
G0029_RS09745	COG0167	dihydroorotate dehydrogenase activity
G0029_RS09770	COG0778	Nitroreductase
G0029_RS09780	COG0513	Belongs to the DEAD box helicase family
G0029_RS09785	COG1278	Cold shock
G0029_RS09800	COG2363	Small membrane protein
G0029_RS09820	COG0625	glutathione transferase activity
G0029_RS09825	COG0659	secondary active sulfate transmembrane transporter activity
G0029_RS09830	COG4585	Histidine kinase
G0029_RS09835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G0029_RS09860	COG0308	aminopeptidase N
G0029_RS09895	COG1253	flavin adenine dinucleotide binding
G0029_RS09925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G0029_RS09930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G0029_RS09945	COG2431	L-lysine efflux transmembrane transporter activity
G0029_RS09960	COG0776	regulation of translation
G0029_RS09990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G0029_RS10025	COG0084	hydrolase, TatD family'
G0029_RS10045	COG1663	tetraacyldisaccharide 4'-kinase activity
G0029_RS10050	COG1132	(ABC) transporter
G0029_RS10060	COG0811	peptide transport
G0029_RS10065	COG1475	DNA binding
G0029_RS10070	COG1192	Involved in chromosome partitioning
G0029_RS10080	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G0029_RS10085	COG3178	'Phosphotransferase
G0029_RS10095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0029_RS10100	COG1923	regulation of RNA biosynthetic process
G0029_RS10110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G0029_RS10115	COG0802	atpase or kinase
G0029_RS10140	COG2707	UPF0756 membrane protein
G0029_RS10160	COG0583	DNA-binding transcription factor activity
G0029_RS10165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0029_RS10185	COG1643	Atp-dependent helicase
G0029_RS10220	COG3634	alkyl hydroperoxide reductase activity
G0029_RS10235	COG1280	lysine exporter protein (LysE YggA)
G0029_RS10250	COG1254	Belongs to the acylphosphatase family
G0029_RS10255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G0029_RS10255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G0029_RS10260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G0029_RS10275	COG1944	ATP diphosphatase activity
G0029_RS10285	COG0582	viral genome integration into host DNA
G0029_RS10320	COG3293	Transposase
G0029_RS10375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G0029_RS10425	COG0012	GTP binding
G0029_RS10440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G0029_RS10455	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G0029_RS10490	COG0386	Belongs to the glutathione peroxidase family
G0029_RS10495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G0029_RS10500	COG0436	Aminotransferase
G0029_RS10520	COG1187	pseudouridine synthase activity
G0029_RS10535	COG1686	Belongs to the peptidase S11 family
G0029_RS10540	COG1252	NADH dehydrogenase
G0029_RS10560	COG0501	Belongs to the peptidase M48B family
G0029_RS10565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G0029_RS10580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G0029_RS10595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G0029_RS10600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G0029_RS10605	COG0527	aspartate kinase activity
G0029_RS10615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G0029_RS10625	COG3038	cytochrome b561
G0029_RS10635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G0029_RS10640	COG2252	PERMEase
G0029_RS10665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G0029_RS10680	COG0693	protein deglycase activity
G0029_RS10685	COG1960	acyl-CoA dehydrogenase activity
G0029_RS10690	COG1301	dicarboxylic acid transport
G0029_RS10695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G0029_RS10700	COG3139	Protein of unknown function (DUF1315)
G0029_RS10705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G0029_RS10710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G0029_RS10720	COG0494	nUDIX hydrolase
G0029_RS10730	COG0642	Histidine kinase
G0029_RS10745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G0029_RS10755	COG1720	tRNA m6t6A37 methyltransferase activity
G0029_RS10840	COG0789	Transcriptional regulator
G0029_RS10845	COG0826	peptidase U32
G0029_RS10850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0029_RS10855	COG3634	alkyl hydroperoxide reductase activity
G0029_RS10880	COG2862	Uncharacterized protein family, UPF0114
G0029_RS10895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0029_RS10940	COG1902	pentaerythritol trinitrate reductase activity
G0029_RS10940	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0029_RS10945	COG0277	FAD linked oxidase domain protein
G0029_RS10955	COG2186	Transcriptional regulator
G0029_RS10970	COG3706	GGDEF domain
G0029_RS10975	COG0418	dihydroorotase activity
G0029_RS10980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G0029_RS10990	COG4771	TonB-dependent receptor
G0029_RS11010	COG0833	amino acid
G0029_RS11025	COG0833	amino acid
G0029_RS11050	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
G0029_RS11060	COG4172	Belongs to the ABC transporter superfamily
G0029_RS11065	COG4239	(ABC) transporter, permease
G0029_RS11070	COG4174	ABC transporter (Permease)
G0029_RS11080	COG1388	LysM domain
G0029_RS11080	COG0741	lytic transglycosylase activity
G0029_RS11100	COG0657	acetylesterase activity
G0029_RS11135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0029_RS11140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0029_RS11160	COG0006	proline dipeptidase activity
G0029_RS11205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G0029_RS11215	COG2234	aminopeptidase activity
G0029_RS11225	COG3384	dioxygenase
G0029_RS11240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G0029_RS11245	COG2878	Part of a membrane complex involved in electron transport
G0029_RS11250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G0029_RS11275	COG0768	penicillin binding
G0029_RS11280	COG0742	ribosomal rna small subunit methyltransferase
G0029_RS11325	COG1597	lipid kinase activity
G0029_RS11330	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G0029_RS11340	COG0477	Major facilitator Superfamily
G0029_RS11345	COG0477	Major facilitator Superfamily
G0029_RS11360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G0029_RS11395	COG1695	Transcriptional regulator
G0029_RS11410	COG0175	sulfate reduction
G0029_RS11425	COG2268	Band 7 protein
G0029_RS11430	COG0726	polysaccharide deacetylase
G0029_RS11430	COG1649	PFAM Uncharacterised BCR, COG1649
G0029_RS11440	COG1215	transferase activity, transferring glycosyl groups
G0029_RS11445	COG1649	PFAM Uncharacterised BCR, COG1649
G0029_RS11445	COG0726	polysaccharide deacetylase
G0029_RS11455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G0029_RS11465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G0029_RS11480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G0029_RS11485	COG1053	succinate dehydrogenase
G0029_RS11490	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G0029_RS11505	COG2072	flavoprotein involved in K transport
G0029_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS11520	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G0029_RS11535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0029_RS11535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G0029_RS11590	COG2321	neutral zinc metallopeptidase
G0029_RS11595	COG2354	Protein conserved in bacteria
G0029_RS11605	COG3293	Transposase
G0029_RS11620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G0029_RS11625	COG1773	rubredoxin
G0029_RS11630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0029_RS11640	COG0583	DNA-binding transcription factor activity
G0029_RS11665	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G0029_RS11670	COG4181	ATPase activity
G0029_RS11720	COG0306	phosphate transporter
G0029_RS11730	COG2376	Dihydroxyacetone kinase
G0029_RS11735	COG2323	membrane
G0029_RS11740	COG0004	ammonium transporteR
G0029_RS11755	COG0642	Histidine kinase
G0029_RS11760	COG0745	RESPONSE REGULATOR receiver
G0029_RS11765	COG2194	sulfuric ester hydrolase activity
G0029_RS11785	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0029_RS11800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0029_RS11805	COG0142	geranyltranstransferase activity
G0029_RS11810	COG3706	GGDEF domain
G0029_RS11820	COG2828	Protein conserved in bacteria
G0029_RS11825	COG1113	amino acid transport
G0029_RS11845	COG3293	Transposase
G0029_RS11855	COG0560	Phosphoserine phosphatase
G0029_RS11865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G0029_RS11875	COG1530	ribonuclease E activity
G0029_RS11880	COG0424	maF-like protein
G0029_RS11885	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G0029_RS11890	COG1792	Involved in formation and maintenance of cell shape
G0029_RS11895	COG1077	Cell shape determining protein MreB Mrl
G0029_RS11900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0029_RS11910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0029_RS11945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G0029_RS11980	COG1053	succinate dehydrogenase
G0029_RS11985	COG0583	DNA-binding transcription factor activity
G0029_RS11995	COG1294	oxidase, subunit
G0029_RS12000	COG1271	oxidase subunit
G0029_RS12035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G0029_RS12045	COG0745	RESPONSE REGULATOR receiver
G0029_RS12050	COG0642	Histidine kinase
G0029_RS12060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G0029_RS12065	COG2814	Major facilitator Superfamily
G0029_RS12070	COG1566	PFAM secretion protein HlyD family protein
G0029_RS12075	COG2050	protein possibly involved in aromatic compounds catabolism
G0029_RS12085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G0029_RS12090	COG1090	epimerase
G0029_RS12100	COG5001	Diguanylate cyclase
G0029_RS12100	COG4251	negative regulation of phosphorylation
G0029_RS12100	COG3706	GGDEF domain
G0029_RS12100	COG2203	Gaf domain
G0029_RS12110	COG0420	3'-5' exonuclease activity
G0029_RS12140	COG0735	belongs to the Fur family
G0029_RS12145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0029_RS12150	COG2914	Belongs to the UPF0125 (RnfH) family
G0029_RS12165	COG0121	glutamine amidotransferase
G0029_RS12175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0029_RS12185	COG0210	DNA helicase
G0029_RS12190	COG2885	chlorophyll binding
G0029_RS12195	COG0204	Acyl-transferase
G0029_RS12215	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G0029_RS12230	COG0583	DNA-binding transcription factor activity
G0029_RS12235	COG1674	ftsk spoiiie
G0029_RS12240	COG0492	ferredoxin-NADP+ reductase activity
G0029_RS12245	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G0029_RS12250	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G0029_RS12255	COG0456	acetyltransferase
G0029_RS12270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G0029_RS12295	COG1981	membrane
G0029_RS12315	COG1652	LysM domain
G0029_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS12340	COG1399	metal-binding, possibly nucleic acid-binding protein
G0029_RS12345	COG3101	peptidyl-lysine hydroxylation
G0029_RS12350	COG0009	L-threonylcarbamoyladenylate synthase
G0029_RS12365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G0029_RS12370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G0029_RS12385	COG4106	trans-aconitate 2-methyltransferase activity
G0029_RS12400	COG0596	Alpha beta hydrolase
G0029_RS12400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0029_RS12400	COG2226	methyltransferase
G0029_RS12405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G0029_RS12410	COG2193	ferroxidase activity
G0029_RS12415	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
G0029_RS12440	COG2801	Transposase and inactivated derivatives
G0029_RS12445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G0029_RS12465	COG0183	Belongs to the thiolase family
G0029_RS12480	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0029_RS12495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0029_RS12500	COG2207	Transcriptional regulator
G0029_RS12510	COG0183	Belongs to the thiolase family
G0029_RS12515	COG1024	Enoyl-CoA hydratase
G0029_RS12515	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0029_RS12535	COG1272	protein, Hemolysin III
G0029_RS12540	COG0477	Major facilitator Superfamily
G0029_RS12545	COG1408	metallophosphoesterase
G0029_RS12550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0029_RS12560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G0029_RS12590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G0029_RS12595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G0029_RS12600	COG0840	transmembrane signaling receptor activity
G0029_RS12615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G0029_RS12620	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G0029_RS12630	COG0625	glutathione transferase activity
G0029_RS12635	COG2969	positive regulation of protein catabolic process
G0029_RS12695	COG3300	MHYT domain
G0029_RS12695	COG5001	Diguanylate cyclase
G0029_RS12700	COG2885	chlorophyll binding
G0029_RS12735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G0029_RS12740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G0029_RS12755	COG0450	alkyl hydroperoxide reductase
G0029_RS12775	COG0285	dihydrofolate synthase activity
G0029_RS12835	COG4206	TonB-dependent receptor
G0029_RS12840	COG2096	Adenosyltransferase
G0029_RS12860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G0029_RS12880	COG1113	amino acid transport
G0029_RS12890	COG0745	RESPONSE REGULATOR receiver
G0029_RS12895	COG2205	protein histidine kinase activity
G0029_RS12905	COG1960	acyl-CoA dehydrogenase activity
G0029_RS12910	COG1960	acyl-CoA dehydrogenase activity
G0029_RS12955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G0029_RS12980	COG0438	transferase activity, transferring glycosyl groups
G0029_RS12995	COG2194	sulfuric ester hydrolase activity
G0029_RS13010	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G0029_RS13015	COG5002	protein histidine kinase activity
G0029_RS13035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G0029_RS13045	COG1704	LemA family
G0029_RS13060	COG1862	Preprotein translocase
G0029_RS13080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0029_RS13100	COG2205	protein histidine kinase activity
G0029_RS13100	COG0784	Response regulator, receiver
G0029_RS13100	COG5002	protein histidine kinase activity
G0029_RS13105	COG1024	Enoyl-CoA hydratase
G0029_RS13110	COG2084	Dehydrogenase
G0029_RS13115	COG3622	Belongs to the hyi family
G0029_RS13130	COG0004	ammonium transporteR
G0029_RS13150	COG0697	spore germination
G0029_RS13155	COG2814	Major facilitator Superfamily
G0029_RS13170	COG0646	methionine synthase
G0029_RS13170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G0029_RS13175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G0029_RS13180	COG0495	leucyl-tRNA aminoacylation
G0029_RS13185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G0029_RS13190	COG2003	Belongs to the UPF0758 family
G0029_RS13195	COG3781	membrane
G0029_RS13200	COG0613	PHP domain protein
G0029_RS13210	COG2350	Protein conserved in bacteria
G0029_RS13245	COG1607	acyl-coa hydrolase
G0029_RS13315	COG1183	phosphatidylcholine synthase activity
G0029_RS13320	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G0029_RS13355	COG0739	heme binding
G0029_RS13355	COG1196	nuclear chromosome segregation
G0029_RS13355	COG0741	lytic transglycosylase activity
G0029_RS13360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G0029_RS13365	COG1702	phosphate starvation-inducible protein PhoH
G0029_RS13370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G0029_RS13415	COG1295	ribonuclease BN
G0029_RS13435	COG0179	Fumarylacetoacetate (FAA) hydrolase
G0029_RS13470	COG0557	exoribonuclease II activity
G0029_RS13475	COG0339	signal peptide processing
G0029_RS13480	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G0029_RS13490	COG0697	spore germination
G0029_RS13515	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G0029_RS13520	COG1960	acyl-CoA dehydrogenase activity
G0029_RS13530	COG2072	flavoprotein involved in K transport
G0029_RS13535	COG0203	ribosomal protein L17
G0029_RS13540	COG0202	RNA polymerase activity
G0029_RS13555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G0029_RS13580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G0029_RS13590	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G0029_RS13595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G0029_RS13645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G0029_RS13660	COG0088	Forms part of the polypeptide exit tunnel
G0029_RS13665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G0029_RS13680	COG0626	cystathionine gamma-synthase activity
G0029_RS13685	COG0433	COG0433 Predicted ATPase
G0029_RS13695	COG1959	2 iron, 2 sulfur cluster binding
G0029_RS13715	COG1301	dicarboxylic acid transport
G0029_RS13720	COG1946	Acyl-CoA thioesterase
G0029_RS13725	COG2937	Belongs to the GPAT DAPAT family
G0029_RS13740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G0029_RS13745	COG1040	competence protein
G0029_RS13760	COG0598	Magnesium transport protein CorA
G0029_RS13770	COG2854	intermembrane phospholipid transfer
G0029_RS13775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G0029_RS13780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G0029_RS13785	COG1127	ABC transporter
G0029_RS13790	COG0513	Belongs to the DEAD box helicase family
G0029_RS13810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0029_RS13815	COG0408	coproporphyrinogen oxidase activity
G0029_RS13835	COG1960	acyl-CoA dehydrogenase activity
G0029_RS13850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0029_RS13860	COG0534	Mate efflux family protein
G0029_RS13875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0029_RS13880	COG0254	rRNA binding
G0029_RS13885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G0029_RS13905	COG2226	methyltransferase
G0029_RS13920	COG1192	Involved in chromosome partitioning
G0029_RS13925	COG0628	permease
G0029_RS13930	COG2032	superoxide dismutase activity
G0029_RS13935	COG1289	transmembrane transporter activity
G0029_RS13945	COG2814	Major facilitator Superfamily
G0029_RS13970	COG0277	FAD linked oxidase domain protein
G0029_RS13975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G0029_RS14000	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G0029_RS14005	COG5380	lipid catabolic process
G0029_RS14010	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G0029_RS14015	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G0029_RS14030	COG0335	large ribosomal subunit rRNA binding
G0029_RS14040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G0029_RS14045	COG0228	four-way junction DNA binding
G0029_RS14080	COG4969	Belongs to the N-Me-Phe pilin family
G0029_RS14090	COG0194	GDP metabolic process
G0029_RS14095	COG1758	RNA polymerase activity
G0029_RS14100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0029_RS14125	COG4969	Belongs to the N-Me-Phe pilin family
G0029_RS14200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G0029_RS14205	COG1704	LemA family
G0029_RS14215	COG0493	'glutamate synthase
G0029_RS14220	COG0070	glutamate synthase
G0029_RS14220	COG0067	glutamate synthase
G0029_RS14220	COG0069	glutamate synthase activity
G0029_RS14270	COG2226	methyltransferase
G0029_RS14280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G0029_RS14285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G0029_RS14305	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0029_RS14345	COG0488	(ABC) transporter
G0029_RS14355	COG4221	oxidoreductase activity
G0029_RS14365	COG0140	phosphoribosyl-ATP diphosphatase activity
G0029_RS14365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G0029_RS14380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0029_RS14380	COG2111	Na H antiporter
G0029_RS14385	COG1006	Multisubunit Na H antiporter MnhC subunit
G0029_RS14390	COG0651	ATP synthesis coupled electron transport
G0029_RS14395	COG1863	multisubunit Na H antiporter MnhE subunit
G0029_RS14400	COG2212	antiporter activity
G0029_RS14405	COG1320	monovalent cation:proton antiporter activity
G0029_RS14415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G0029_RS14425	COG0195	Participates in both transcription termination and antitermination
G0029_RS14430	COG0779	Required for maturation of 30S ribosomal subunits
G0029_RS14485	COG0237	dephospho-CoA kinase activity
G0029_RS14495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0029_RS14500	COG3123	guanosine phosphorylase activity
G0029_RS14505	COG0497	DNA recombination
G0029_RS14520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G0029_RS14535	COG1289	transmembrane transporter activity
G0029_RS14550	COG1132	(ABC) transporter
G0029_RS14560	COG1538	Outer membrane efflux protein
G0029_RS14570	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G0029_RS14585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G0029_RS14590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G0029_RS14600	COG0772	Belongs to the SEDS family
G0029_RS14625	COG4974	Belongs to the 'phage' integrase family
G0029_RS14640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G0029_RS14650	COG2197	response regulator
G0029_RS14665	COG0793	Belongs to the peptidase S41A family
G0029_RS14670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G0029_RS14675	COG0795	lipopolysaccharide-transporting ATPase activity
G0029_RS14680	COG0795	lipopolysaccharide-transporting ATPase activity
G0029_RS14705	COG0586	Pfam SNARE associated Golgi protein
G0029_RS14720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0029_RS14720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0029_RS14730	COG0004	ammonium transporteR
G0029_RS14735	COG0347	Belongs to the P(II) protein family
G0029_RS14765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G0029_RS14780	COG0318	PFAM AMP-dependent synthetase and ligase
G0029_RS14790	COG0477	Major facilitator Superfamily
G0029_RS14795	COG2860	membrane
G0029_RS14805	COG1253	flavin adenine dinucleotide binding
G0029_RS14820	COG2814	Major facilitator Superfamily
G0029_RS14835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0029_RS14840	COG0477	Major facilitator Superfamily
G0029_RS14865	COG2814	Major facilitator Superfamily
G0029_RS14925	COG0758	DNA mediated transformation
G0029_RS14945	COG0386	Belongs to the glutathione peroxidase family
G0029_RS15040	COG1121	(ABC) transporter
G0029_RS15045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G0029_RS15055	COG2837	iron assimilation
G0029_RS15075	COG0436	Aminotransferase
G0029_RS15080	COG0534	Mate efflux family protein
G0029_RS15085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0029_RS15105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G0029_RS15125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G0029_RS15185	COG3706	GGDEF domain
G0029_RS15190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0029_RS15190	COG0519	Catalyzes the synthesis of GMP from XMP
G0029_RS15195	COG2259	Doxx family
G0029_RS15200	COG0586	Pfam SNARE associated Golgi protein
G0029_RS15215	COG1192	Involved in chromosome partitioning
G0029_RS15225	COG0271	Belongs to the BolA IbaG family
G0029_RS15285	COG4974	Belongs to the 'phage' integrase family
G0029_RS15355	COG4221	oxidoreductase activity
G0029_RS15380	COG0659	secondary active sulfate transmembrane transporter activity
G0029_RS15435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G0029_RS15440	COG2011	ABC-type metal ion transport system permease component
G0029_RS15445	COG0281	malic enzyme
G0029_RS15450	COG1454	alcohol dehydrogenase
G0029_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
G0029_RS15485	COG1309	transcriptional regulator
G0029_RS15495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G0029_RS15500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G0029_RS15505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G0029_RS15510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G0029_RS15515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G0029_RS15520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G0029_RS15560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0029_RS15570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0029_RS15585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G0029_RS15590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G0029_RS15595	COG1216	Glycosyl transferase, family 2
G0029_RS15610	COG0438	transferase activity, transferring glycosyl groups
G0029_RS15625	COG2244	polysaccharide biosynthetic process
G0029_RS15630	COG2089	acid synthase
G0029_RS15635	COG1083	cytidylyl-transferase
G0029_RS15645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G0029_RS15655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G0029_RS15660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G0029_RS15665	COG0438	transferase activity, transferring glycosyl groups
G0029_RS15670	COG0438	transferase activity, transferring glycosyl groups
G0029_RS15675	COG0438	transferase activity, transferring glycosyl groups
G0029_RS15685	COG0110	maltose O-acetyltransferase activity
G0029_RS15700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G0029_RS15705	COG1596	polysaccharide export
G0029_RS15740	COG1194	a g-specific adenine glycosylase
G0029_RS15755	COG2818	Glycosylase
G0029_RS15760	COG1064	alcohol dehydrogenase
G0029_RS15770	COG0675	Transposase, IS605 OrfB family
G0029_RS15795	COG3307	-O-antigen
G0029_RS15815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0029_RS15820	COG1309	transcriptional regulator
G0029_RS15830	COG2233	PERMEase
G0029_RS15835	COG0583	DNA-binding transcription factor activity
G0029_RS15880	COG0129	dihydroxy-acid dehydratase activity
G0029_RS15885	COG0129	dihydroxy-acid dehydratase activity
G0029_RS15895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G0029_RS15895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G0029_RS15905	COG0733	neurotransmitter:sodium symporter activity
G0029_RS15910	COG3738	Protein conserved in bacteria
G0029_RS15915	COG1012	belongs to the aldehyde dehydrogenase family
G0029_RS15920	COG2814	Major facilitator Superfamily
G0029_RS15960	COG4716	Myosin-crossreactive antigen
G0029_RS15980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G0029_RS15985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G0029_RS15990	COG2951	lytic endotransglycosylase activity
G0029_RS15995	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G0029_RS16005	COG0675	Transposase, IS605 OrfB family
G0029_RS16020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0029_RS16035	COG2388	GCN5-related N-acetyl-transferase
G0029_RS16040	COG2814	Major facilitator Superfamily
G0029_RS16045	COG0861	Integral membrane protein TerC family
G0029_RS16055	COG0402	S-adenosylhomocysteine deaminase activity
G0029_RS16075	COG1230	cation diffusion facilitator family transporter
G0029_RS16105	COG0706	membrane insertase activity
G0029_RS16110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G0029_RS16115	COG0594	ribonuclease P activity
G0029_RS16200	COG3046	protein related to deoxyribodipyrimidine photolyase
G0029_RS16205	COG2816	NAD+ diphosphatase activity
G0029_RS16230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G0029_RS16245	COG0642	Histidine kinase
G0029_RS16250	COG0745	RESPONSE REGULATOR receiver
G0029_RS16315	COG2801	Transposase and inactivated derivatives
G0029_RS16350	COG3077	Addiction module antitoxin, RelB DinJ family
G0029_RS16355	COG2801	Transposase and inactivated derivatives
G0029_RS16370	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
G0029_RS16430	COG0582	viral genome integration into host DNA
G0029_RS16975	COG1475	DNA binding
G0029_RS16980	COG1192	Involved in chromosome partitioning
G0029_RS17080	COG2801	Transposase and inactivated derivatives
G0029_RS17085	COG0183	Belongs to the thiolase family
G0029_RS17090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0029_RS17095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0029_RS17105	COG4829	muconolactone delta-isomerase
G0029_RS17110	COG4948	Mandelate Racemase Muconate Lactonizing
G0029_RS17145	COG4638	Rieske (2fe-2S)
G0029_RS17165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0029_RS17190	COG4191	Histidine kinase
G0029_RS17230	COG1230	cation diffusion facilitator family transporter
G0029_RS17245	COG0582	viral genome integration into host DNA
G0029_RS17255	COG1192	Involved in chromosome partitioning
G0029_RS17280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G0029_RS17315	COG2184	nucleotidyltransferase activity
G0029_RS17325	COG4372	Transposase
G0029_RS17350	COG1785	Belongs to the alkaline phosphatase family
G0029_RS17480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G0029_RS17490	COG5002	protein histidine kinase activity
G0029_RS17495	COG0745	RESPONSE REGULATOR receiver
G0029_RS17500	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
G0029_RS17595	COG1373	ATPase (AAA superfamily
G0029_RS17620	COG3173	Aminoglycoside phosphotransferase
G0029_RS17800	COG2026	Addiction module toxin, RelE StbE family
G0029_RS17835	COG1192	Involved in chromosome partitioning
G0029_RS17935	COG1794	racemase activity, acting on amino acids and derivatives
G0029_RS17995	COG3657	addiction module killer protein
G0029_RS18000	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0029_RS18035	COG3657	addiction module killer protein
G0029_RS18040	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0029_RS18065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis