locus-tag	class	description
GJD93_RS00005	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GJD93_RS00025	COG1192	Involved in chromosome partitioning
GJD93_RS00050	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GJD93_RS00100	COG3077	Addiction module antitoxin, RelB DinJ family
GJD93_RS00115	COG2132	Multicopper oxidase
GJD93_RS00165	COG2826	transposase and inactivated derivatives, IS30 family
GJD93_RS00185	COG1660	Displays ATPase and GTPase activities
GJD93_RS00205	COG1570	exodeoxyribonuclease VII activity
GJD93_RS00220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GJD93_RS00225	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GJD93_RS00230	COG0732	type I restriction modification DNA specificity domain
GJD93_RS00245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJD93_RS00255	COG3173	Aminoglycoside phosphotransferase
GJD93_RS00275	COG1683	Conserved Protein
GJD93_RS00315	COG1230	cation diffusion facilitator family transporter
GJD93_RS00330	COG0582	viral genome integration into host DNA
GJD93_RS00375	COG3210	domain, Protein
GJD93_RS00380	COG2831	hemolysin activation secretion protein
GJD93_RS00395	COG1373	ATPase (AAA superfamily
GJD93_RS00415	COG4372	Transposase
GJD93_RS00480	COG3012	SEC-C Motif Domain Protein
GJD93_RS00505	COG2194	sulfuric ester hydrolase activity
GJD93_RS00510	COG0642	Histidine kinase
GJD93_RS00515	COG0745	RESPONSE REGULATOR receiver
GJD93_RS00570	COG1192	Involved in chromosome partitioning
GJD93_RS00585	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GJD93_RS00600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GJD93_RS00635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJD93_RS00645	COG1570	exodeoxyribonuclease VII activity
GJD93_RS00690	COG3173	Aminoglycoside phosphotransferase
GJD93_RS00695	COG0488	(ABC) transporter
GJD93_RS00720	COG0488	(ABC) transporter
GJD93_RS00755	COG0745	RESPONSE REGULATOR receiver
GJD93_RS00760	COG5002	protein histidine kinase activity
GJD93_RS00770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJD93_RS00790	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJD93_RS00795	COG3657	addiction module killer protein
GJD93_RS00805	COG0659	secondary active sulfate transmembrane transporter activity
GJD93_RS00810	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJD93_RS00815	COG3657	addiction module killer protein
GJD93_RS00965	COG0592	DNA-directed DNA polymerase activity
GJD93_RS00975	COG0187	DNA topoisomerase II activity
GJD93_RS00985	COG0488	(ABC) transporter
GJD93_RS01000	COG0316	Belongs to the HesB IscA family
GJD93_RS01005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GJD93_RS01010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GJD93_RS01040	COG2814	Major facilitator Superfamily
GJD93_RS01045	COG2133	pyrroloquinoline quinone binding
GJD93_RS01050	COG1047	Peptidyl-prolyl cis-trans
GJD93_RS01060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GJD93_RS01065	COG0196	riboflavin kinase activity
GJD93_RS01075	COG1309	transcriptional regulator
GJD93_RS01080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GJD93_RS01080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GJD93_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
GJD93_RS01105	COG0546	phosphoglycolate phosphatase activity
GJD93_RS01110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GJD93_RS01125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GJD93_RS01140	COG3023	N-Acetylmuramoyl-L-alanine amidase
GJD93_RS01160	COG1064	alcohol dehydrogenase
GJD93_RS01165	COG2818	Glycosylase
GJD93_RS01180	COG1194	a g-specific adenine glycosylase
GJD93_RS01195	COG5487	UPF0391 membrane protein
GJD93_RS01200	COG2983	Belongs to the UPF0260 family
GJD93_RS01205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GJD93_RS01215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GJD93_RS01225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GJD93_RS01230	COG2814	Major facilitator Superfamily
GJD93_RS01240	COG1335	isochorismatase
GJD93_RS01255	COG3830	Belongs to the UPF0237 family
GJD93_RS01255	COG0560	Phosphoserine phosphatase
GJD93_RS01310	COG0534	Mate efflux family protein
GJD93_RS01315	COG0436	Aminotransferase
GJD93_RS01320	COG2733	membrane
GJD93_RS01335	COG2918	glutathione biosynthetic process
GJD93_RS01350	COG3150	esterase
GJD93_RS01365	COG0471	metal ion transport
GJD93_RS01405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GJD93_RS01420	COG1393	Belongs to the ArsC family
GJD93_RS01425	COG0708	Exodeoxyribonuclease III
GJD93_RS01430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GJD93_RS01455	COG0189	ligase activity
GJD93_RS01475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GJD93_RS01485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GJD93_RS01490	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GJD93_RS01515	COG2119	membrane
GJD93_RS01520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GJD93_RS01520	COG0426	domain, Protein
GJD93_RS01545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GJD93_RS01570	COG1902	pentaerythritol trinitrate reductase activity
GJD93_RS01575	COG1519	Transferase
GJD93_RS01585	COG0668	transmembrane transport
GJD93_RS01590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GJD93_RS01645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GJD93_RS01655	COG2814	Major facilitator Superfamily
GJD93_RS01660	COG0583	DNA-binding transcription factor activity
GJD93_RS01700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GJD93_RS01785	COG4221	oxidoreductase activity
GJD93_RS01790	COG4372	Transposase
GJD93_RS01895	COG3173	Aminoglycoside phosphotransferase
GJD93_RS01905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJD93_RS01945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GJD93_RS01990	COG3077	Addiction module antitoxin, RelB DinJ family
GJD93_RS01995	COG1764	response to oxidative stress
GJD93_RS02000	COG1846	Transcriptional regulator
GJD93_RS02015	COG2801	Transposase and inactivated derivatives
GJD93_RS02030	COG3077	Addiction module antitoxin, RelB DinJ family
GJD93_RS02055	COG1570	exodeoxyribonuclease VII activity
GJD93_RS02070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GJD93_RS02145	COG0556	nucleotide-excision repair
GJD93_RS02150	COG1104	cysteine desulfurase activity
GJD93_RS02160	COG3756	Protein conserved in bacteria
GJD93_RS02190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJD93_RS02200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GJD93_RS02205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GJD93_RS02210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GJD93_RS02240	COG3158	transport of potassium into the cell
GJD93_RS02280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GJD93_RS02295	COG0697	spore germination
GJD93_RS02315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GJD93_RS02335	COG3547	Transposase (IS116 IS110 IS902 family)
GJD93_RS02370	COG0427	acetyl-CoA hydrolase
GJD93_RS02400	COG4221	oxidoreductase activity
GJD93_RS02410	COG0488	(ABC) transporter
GJD93_RS02430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GJD93_RS02440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GJD93_RS02445	COG0275	rRNA processing
GJD93_RS02460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GJD93_RS02465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJD93_RS02470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJD93_RS02475	COG2226	methyltransferase
GJD93_RS02525	COG0069	glutamate synthase activity
GJD93_RS02525	COG0067	glutamate synthase
GJD93_RS02525	COG0070	glutamate synthase
GJD93_RS02530	COG0493	'glutamate synthase
GJD93_RS02535	COG1704	LemA family
GJD93_RS02540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GJD93_RS02565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GJD93_RS02590	COG3307	-O-antigen
GJD93_RS02610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJD93_RS02615	COG1758	RNA polymerase activity
GJD93_RS02620	COG0194	GDP metabolic process
GJD93_RS02640	COG4966	pilus assembly protein PilW
GJD93_RS02665	COG0228	four-way junction DNA binding
GJD93_RS02670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GJD93_RS02680	COG0335	large ribosomal subunit rRNA binding
GJD93_RS02690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GJD93_RS02695	COG5380	lipid catabolic process
GJD93_RS02700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GJD93_RS02715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GJD93_RS02720	COG0277	FAD linked oxidase domain protein
GJD93_RS02745	COG2814	Major facilitator Superfamily
GJD93_RS02750	COG2032	superoxide dismutase activity
GJD93_RS02755	COG0628	permease
GJD93_RS02760	COG1192	Involved in chromosome partitioning
GJD93_RS02770	COG2226	methyltransferase
GJD93_RS02785	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJD93_RS02790	COG0254	rRNA binding
GJD93_RS02805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GJD93_RS02810	COG0534	Mate efflux family protein
GJD93_RS02820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJD93_RS02850	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS02870	COG0408	coproporphyrinogen oxidase activity
GJD93_RS02875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJD93_RS02895	COG0513	Belongs to the DEAD box helicase family
GJD93_RS02900	COG1127	ABC transporter
GJD93_RS02905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GJD93_RS02910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GJD93_RS02915	COG2854	intermembrane phospholipid transfer
GJD93_RS02925	COG0598	Magnesium transport protein CorA
GJD93_RS02940	COG1040	competence protein
GJD93_RS02945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GJD93_RS02955	COG2937	Belongs to the GPAT DAPAT family
GJD93_RS02960	COG1946	Acyl-CoA thioesterase
GJD93_RS02965	COG1301	dicarboxylic acid transport
GJD93_RS02980	COG1959	2 iron, 2 sulfur cluster binding
GJD93_RS02990	COG0433	COG0433 Predicted ATPase
GJD93_RS03015	COG0088	Forms part of the polypeptide exit tunnel
GJD93_RS03030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GJD93_RS03070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GJD93_RS03080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GJD93_RS03085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GJD93_RS03095	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GJD93_RS03120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GJD93_RS03130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GJD93_RS03140	COG0203	ribosomal protein L17
GJD93_RS03145	COG2072	flavoprotein involved in K transport
GJD93_RS03150	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS03155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GJD93_RS03190	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GJD93_RS03195	COG0339	signal peptide processing
GJD93_RS03205	COG0557	exoribonuclease II activity
GJD93_RS03235	COG0179	Fumarylacetoacetate (FAA) hydrolase
GJD93_RS03260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GJD93_RS03315	COG2813	Specifically methylates the guanine in position
GJD93_RS03315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GJD93_RS03320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GJD93_RS03325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GJD93_RS03335	COG3128	pkhd-type hydroxylase
GJD93_RS03340	COG4774	siderophore transport
GJD93_RS03345	COG4771	TonB-dependent receptor
GJD93_RS03355	COG0740	serine-type endopeptidase activity
GJD93_RS03370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GJD93_RS03370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GJD93_RS03375	COG2890	protein-(glutamine-N5) methyltransferase activity
GJD93_RS03380	COG0280	phosphate acetyltransferase
GJD93_RS03380	COG0857	belongs to the CobB CobQ family
GJD93_RS03385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GJD93_RS03400	COG2267	carboxylic ester hydrolase activity
GJD93_RS03430	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GJD93_RS03445	COG0084	hydrolase, TatD family'
GJD93_RS03450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GJD93_RS03455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJD93_RS03465	COG2814	Major facilitator Superfamily
GJD93_RS03495	COG3622	Belongs to the hyi family
GJD93_RS03500	COG2084	Dehydrogenase
GJD93_RS03505	COG1024	Enoyl-CoA hydratase
GJD93_RS03510	COG2205	protein histidine kinase activity
GJD93_RS03510	COG0784	Response regulator, receiver
GJD93_RS03510	COG5002	protein histidine kinase activity
GJD93_RS03530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJD93_RS03550	COG1862	Preprotein translocase
GJD93_RS03570	COG2203	Gaf domain
GJD93_RS03570	COG3706	GGDEF domain
GJD93_RS03570	COG4251	negative regulation of phosphorylation
GJD93_RS03570	COG5001	Diguanylate cyclase
GJD93_RS03575	COG1704	LemA family
GJD93_RS03585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GJD93_RS03600	COG0784	Response regulator, receiver
GJD93_RS03600	COG5002	protein histidine kinase activity
GJD93_RS03600	COG2205	protein histidine kinase activity
GJD93_RS03605	COG1538	Outer membrane efflux protein
GJD93_RS03610	COG1136	(ABC) transporter
GJD93_RS03610	COG0577	efflux transmembrane transporter activity
GJD93_RS03615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD93_RS03620	COG2703	oxygen carrier activity
GJD93_RS03645	COG0028	Belongs to the TPP enzyme family
GJD93_RS03675	COG0726	polysaccharide deacetylase
GJD93_RS03680	COG0297	glycogen (starch) synthase activity
GJD93_RS03730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GJD93_RS03745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJD93_RS03765	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS03770	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS03780	COG2205	protein histidine kinase activity
GJD93_RS03785	COG0745	RESPONSE REGULATOR receiver
GJD93_RS03790	COG0675	Transposase, IS605 OrfB family
GJD93_RS03795	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GJD93_RS03810	COG2096	Adenosyltransferase
GJD93_RS03815	COG4206	TonB-dependent receptor
GJD93_RS03845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GJD93_RS03885	COG2975	iron-sulfur cluster assembly
GJD93_RS03905	COG1426	Protein conserved in bacteria
GJD93_RS03925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GJD93_RS03940	COG3956	TIGRFAM MazG family protein
GJD93_RS03945	COG1596	polysaccharide export
GJD93_RS03945	COG1555	photosystem II stabilization
GJD93_RS03950	COG0617	tRNA 3'-terminal CCA addition
GJD93_RS03955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GJD93_RS03970	COG1660	Displays ATPase and GTPase activities
GJD93_RS03980	COG3028	Belongs to the UPF0307 family
GJD93_RS03985	COG0318	PFAM AMP-dependent synthetase and ligase
GJD93_RS04015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GJD93_RS04020	COG0625	glutathione transferase activity
GJD93_RS04030	COG1238	metal cluster binding
GJD93_RS04075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GJD93_RS04080	COG0072	phenylalanine-tRNA ligase activity
GJD93_RS04105	COG0248	Ppx GppA phosphatase
GJD93_RS04115	COG0037	tRNA processing
GJD93_RS04155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GJD93_RS04220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GJD93_RS04225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GJD93_RS04275	COG0494	nUDIX hydrolase
GJD93_RS04285	COG1214	PFAM Peptidase M22, glycoprotease
GJD93_RS04290	COG1968	undecaprenyl-diphosphatase activity
GJD93_RS04310	COG4269	membrane
GJD93_RS04325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GJD93_RS04335	COG2132	Multicopper oxidase
GJD93_RS04355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GJD93_RS04365	COG0352	thiamine-phosphate diphosphorylase activity
GJD93_RS04365	COG0351	phosphomethylpyrimidine kinase
GJD93_RS04380	COG1981	membrane
GJD93_RS04420	COG0456	acetyltransferase
GJD93_RS04430	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GJD93_RS04435	COG0492	ferredoxin-NADP+ reductase activity
GJD93_RS04440	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GJD93_RS04440	COG1674	ftsk spoiiie
GJD93_RS04455	COG2894	cell division
GJD93_RS04470	COG0204	Acyl-transferase
GJD93_RS04475	COG2885	chlorophyll binding
GJD93_RS04480	COG0210	DNA helicase
GJD93_RS04485	COG0756	dUTP diphosphatase activity
GJD93_RS04490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJD93_RS04495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GJD93_RS04505	COG0121	glutamine amidotransferase
GJD93_RS04520	COG2914	Belongs to the UPF0125 (RnfH) family
GJD93_RS04525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GJD93_RS04530	COG0735	belongs to the Fur family
GJD93_RS04560	COG0420	3'-5' exonuclease activity
GJD93_RS04570	COG1090	epimerase
GJD93_RS04575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GJD93_RS04585	COG2050	protein possibly involved in aromatic compounds catabolism
GJD93_RS04595	COG1022	Amp-dependent synthetase and ligase
GJD93_RS04605	COG0300	oxidoreductase activity
GJD93_RS04620	COG0730	response to heat
GJD93_RS04630	COG4185	zeta toxin
GJD93_RS04640	COG0577	efflux transmembrane transporter activity
GJD93_RS04640	COG1136	(ABC) transporter
GJD93_RS04665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GJD93_RS04680	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GJD93_RS04695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJD93_RS04705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJD93_RS04710	COG1077	Cell shape determining protein MreB Mrl
GJD93_RS04715	COG1792	Involved in formation and maintenance of cell shape
GJD93_RS04720	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GJD93_RS04725	COG0424	maF-like protein
GJD93_RS04730	COG1530	ribonuclease E activity
GJD93_RS04735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GJD93_RS04745	COG0560	Phosphoserine phosphatase
GJD93_RS04765	COG1840	ABC-type Fe3 transport system, periplasmic component
GJD93_RS04770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GJD93_RS04775	COG1113	amino acid transport
GJD93_RS04780	COG2828	Protein conserved in bacteria
GJD93_RS04785	COG0142	geranyltranstransferase activity
GJD93_RS04795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJD93_RS04805	COG0649	NAD binding
GJD93_RS04805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJD93_RS04815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GJD93_RS04830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJD93_RS04840	COG0713	ATP synthesis coupled electron transport
GJD93_RS04845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GJD93_RS04850	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJD93_RS04865	COG1278	Cold shock
GJD93_RS04870	COG1278	Cold shock
GJD93_RS04875	COG0583	DNA-binding transcription factor activity
GJD93_RS04900	COG0668	transmembrane transport
GJD93_RS04910	COG2081	HI0933 family
GJD93_RS04915	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GJD93_RS04925	COG4716	Myosin-crossreactive antigen
GJD93_RS04950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJD93_RS04950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJD93_RS04955	COG0489	protein tyrosine kinase activity
GJD93_RS04995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD93_RS05020	COG0840	transmembrane signaling receptor activity
GJD93_RS05025	COG2198	Histidine kinase
GJD93_RS05025	COG0643	Histidine kinase
GJD93_RS05035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJD93_RS05040	COG5510	response to toxic substance
GJD93_RS05050	COG2832	Protein of unknown function (DUF454)
GJD93_RS05120	COG1289	transmembrane transporter activity
GJD93_RS05125	COG2814	Major facilitator Superfamily
GJD93_RS05135	COG0786	glutamate:sodium symporter activity
GJD93_RS05140	COG2059	Chromate
GJD93_RS05145	COG1752	Esterase of the alpha-beta hydrolase superfamily
GJD93_RS05150	COG1607	acyl-coa hydrolase
GJD93_RS05160	COG0523	cobalamin synthesis protein
GJD93_RS05165	COG4681	YaeQ
GJD93_RS05175	COG2203	Gaf domain
GJD93_RS05175	COG2199	diguanylate cyclase activity
GJD93_RS05180	COG3118	belongs to the thioredoxin family
GJD93_RS05210	COG1192	Involved in chromosome partitioning
GJD93_RS05240	COG3328	transposase activity
GJD93_RS05255	COG1253	flavin adenine dinucleotide binding
GJD93_RS05280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GJD93_RS05285	COG0742	ribosomal rna small subunit methyltransferase
GJD93_RS05290	COG0768	penicillin binding
GJD93_RS05315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GJD93_RS05320	COG2878	Part of a membrane complex involved in electron transport
GJD93_RS05325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GJD93_RS05335	COG3384	dioxygenase
GJD93_RS05345	COG2234	aminopeptidase activity
GJD93_RS05355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJD93_RS05375	COG2186	Transcriptional regulator
GJD93_RS05385	COG0277	FAD linked oxidase domain protein
GJD93_RS05400	COG3706	GGDEF domain
GJD93_RS05420	COG0642	Histidine kinase
GJD93_RS05425	COG0745	RESPONSE REGULATOR receiver
GJD93_RS05430	COG2194	sulfuric ester hydrolase activity
GJD93_RS05440	COG0789	Transcriptional regulator
GJD93_RS05460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GJD93_RS05465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GJD93_RS05470	COG4680	protein conserved in bacteria
GJD93_RS05495	COG3079	Belongs to the UPF0149 family
GJD93_RS05500	COG0006	proline dipeptidase activity
GJD93_RS05510	COG3077	Addiction module antitoxin, RelB DinJ family
GJD93_RS05515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJD93_RS05520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJD93_RS05550	COG2816	NAD+ diphosphatase activity
GJD93_RS05560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJD93_RS05565	COG1388	LysM domain
GJD93_RS05565	COG0741	lytic transglycosylase activity
GJD93_RS05565	COG0741	lytic transglycosylase activity
GJD93_RS05565	COG1388	LysM domain
GJD93_RS05570	COG4166	transmembrane transport
GJD93_RS05575	COG4174	ABC transporter (Permease)
GJD93_RS05580	COG4239	(ABC) transporter, permease
GJD93_RS05585	COG4172	Belongs to the ABC transporter superfamily
GJD93_RS05600	COG0833	amino acid
GJD93_RS05610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJD93_RS05615	COG0418	dihydroorotase activity
GJD93_RS05620	COG4251	negative regulation of phosphorylation
GJD93_RS05620	COG3706	GGDEF domain
GJD93_RS05620	COG2203	Gaf domain
GJD93_RS05620	COG5001	Diguanylate cyclase
GJD93_RS05630	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJD93_RS05630	COG1902	pentaerythritol trinitrate reductase activity
GJD93_RS05720	COG2885	chlorophyll binding
GJD93_RS05725	COG0047	phosphoribosylformylglycinamidine synthase activity
GJD93_RS05725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJD93_RS05735	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GJD93_RS05745	COG0280	phosphate acetyltransferase
GJD93_RS05745	COG0281	malic enzyme
GJD93_RS05755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GJD93_RS05760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GJD93_RS05765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GJD93_RS05775	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GJD93_RS05790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GJD93_RS05795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD93_RS05800	COG2175	clavaminate synthase activity
GJD93_RS05815	COG0024	Methionine aminopeptidase
GJD93_RS05820	COG0052	Belongs to the universal ribosomal protein uS2 family
GJD93_RS05845	COG2951	lytic endotransglycosylase activity
GJD93_RS05860	COG0842	Transport permease protein
GJD93_RS05865	COG1131	(ABC) transporter
GJD93_RS05955	COG0305	Participates in initiation and elongation during chromosome replication
GJD93_RS06010	COG3728	DNA packaging
GJD93_RS06115	COG0582	viral genome integration into host DNA
GJD93_RS06120	COG0582	viral genome integration into host DNA
GJD93_RS06160	COG2184	nucleotidyltransferase activity
GJD93_RS06210	COG0657	acetylesterase activity
GJD93_RS06215	COG1454	alcohol dehydrogenase
GJD93_RS06240	COG1028	Short-chain dehydrogenase reductase Sdr
GJD93_RS06250	COG1028	Short-chain dehydrogenase reductase Sdr
GJD93_RS06255	COG3177	Filamentation induced by cAMP protein fic
GJD93_RS06295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GJD93_RS06305	COG3547	Transposase (IS116 IS110 IS902 family)
GJD93_RS06330	COG3634	alkyl hydroperoxide reductase activity
GJD93_RS06335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GJD93_RS06340	COG0826	peptidase U32
GJD93_RS06350	COG0640	Transcriptional regulator
GJD93_RS06355	COG0798	PFAM Bile acid sodium symporter
GJD93_RS06360	COG0431	NADPH-dependent FMN reductase
GJD93_RS06365	COG0789	Transcriptional regulator
GJD93_RS06390	COG1720	tRNA m6t6A37 methyltransferase activity
GJD93_RS06405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GJD93_RS06420	COG0642	Histidine kinase
GJD93_RS06430	COG0352	thiamine-phosphate diphosphorylase activity
GJD93_RS06440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJD93_RS06445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GJD93_RS06450	COG3139	Protein of unknown function (DUF1315)
GJD93_RS06460	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS06470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GJD93_RS06475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GJD93_RS06495	COG0415	Belongs to the DNA photolyase family
GJD93_RS06500	COG1047	Peptidyl-prolyl cis-trans
GJD93_RS06505	COG1686	Belongs to the peptidase S11 family
GJD93_RS06605	COG0305	Participates in initiation and elongation during chromosome replication
GJD93_RS06670	COG1783	phage Terminase large subunit
GJD93_RS06675	COG3567	Phage-associated protein, HI1409 family
GJD93_RS06680	COG2369	cell adhesion
GJD93_RS06685	COG3566	protein conserved in bacteria
GJD93_RS06810	COG0582	viral genome integration into host DNA
GJD93_RS06815	COG2026	Addiction module toxin, RelE StbE family
GJD93_RS06830	COG0612	Peptidase, M16
GJD93_RS06865	COG0352	thiamine-phosphate diphosphorylase activity
GJD93_RS06900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJD93_RS06900	COG1017	nitric oxide dioxygenase activity
GJD93_RS06965	COG1643	Atp-dependent helicase
GJD93_RS06985	COG0517	IMP dehydrogenase activity
GJD93_RS06985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GJD93_RS06990	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GJD93_RS07000	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GJD93_RS07005	COG1137	ATPase activity
GJD93_RS07025	COG4122	O-methyltransferase activity
GJD93_RS07035	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GJD93_RS07060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GJD93_RS07100	COG2011	ABC-type metal ion transport system permease component
GJD93_RS07105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJD93_RS07110	COG1464	Belongs to the NlpA lipoprotein family
GJD93_RS07125	COG0138	bifunctional purine biosynthesis protein purh
GJD93_RS07130	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GJD93_RS07175	COG0183	Belongs to the thiolase family
GJD93_RS07180	COG3243	poly(R)-hydroxyalkanoic acid synthase
GJD93_RS07195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GJD93_RS07205	COG0305	Participates in initiation and elongation during chromosome replication
GJD93_RS07215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GJD93_RS07220	COG0360	Binds together with S18 to 16S ribosomal RNA
GJD93_RS07230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GJD93_RS07235	COG1845	cytochrome c oxidase, subunit III
GJD93_RS07240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GJD93_RS07245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GJD93_RS07270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJD93_RS07285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GJD93_RS07295	COG3781	membrane
GJD93_RS07315	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS07320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GJD93_RS07330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GJD93_RS07340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GJD93_RS07355	COG0477	Major facilitator Superfamily
GJD93_RS07360	COG0729	surface antigen
GJD93_RS07395	COG0308	aminopeptidase N
GJD93_RS07405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD93_RS07415	COG0589	response to stress
GJD93_RS07420	COG0589	response to stress
GJD93_RS07430	COG3135	benzoate transporter
GJD93_RS07440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GJD93_RS07455	COG0183	Belongs to the thiolase family
GJD93_RS07470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GJD93_RS07475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GJD93_RS07480	COG0824	Thioesterase
GJD93_RS07485	COG1454	alcohol dehydrogenase
GJD93_RS07490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GJD93_RS07510	COG2197	response regulator
GJD93_RS07515	COG4585	Histidine kinase
GJD93_RS07520	COG2850	peptidyl-arginine hydroxylation
GJD93_RS07525	COG0424	maF-like protein
GJD93_RS07535	COG0126	phosphoglycerate kinase activity
GJD93_RS07560	COG0778	Nitroreductase
GJD93_RS07570	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD93_RS07580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GJD93_RS07605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJD93_RS07610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GJD93_RS07615	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS07620	COG2267	carboxylic ester hydrolase activity
GJD93_RS07630	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJD93_RS07630	COG1902	pentaerythritol trinitrate reductase activity
GJD93_RS07660	COG0148	phosphopyruvate hydratase activity
GJD93_RS07665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GJD93_RS07675	COG0772	Belongs to the SEDS family
GJD93_RS07700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GJD93_RS07705	COG0730	response to heat
GJD93_RS07710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD93_RS07715	COG2207	Transcriptional regulator
GJD93_RS07720	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJD93_RS07735	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS07740	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS07775	COG4890	Cyd operon protein YbgT
GJD93_RS07780	COG1294	oxidase, subunit
GJD93_RS07795	COG1585	Membrane protein implicated in regulation of membrane protease activity
GJD93_RS07805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJD93_RS07825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GJD93_RS07830	COG0569	domain protein
GJD93_RS07840	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GJD93_RS07860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GJD93_RS07865	COG0542	response to heat
GJD93_RS07895	COG0372	Belongs to the citrate synthase family
GJD93_RS07910	COG1058	Belongs to the CinA family
GJD93_RS07910	COG1546	Belongs to the CinA family
GJD93_RS07950	COG2814	Major facilitator Superfamily
GJD93_RS07960	COG3706	GGDEF domain
GJD93_RS07970	COG0668	transmembrane transport
GJD93_RS07975	COG3122	Protein conserved in bacteria
GJD93_RS07980	COG3619	membrane
GJD93_RS08000	COG2937	Belongs to the GPAT DAPAT family
GJD93_RS08005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GJD93_RS08015	COG0183	Belongs to the thiolase family
GJD93_RS08020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GJD93_RS08025	COG0183	Belongs to the thiolase family
GJD93_RS08030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GJD93_RS08035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GJD93_RS08040	COG3135	benzoate transporter
GJD93_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
GJD93_RS08050	COG0633	Ferredoxin
GJD93_RS08050	COG0543	2 iron, 2 sulfur cluster binding
GJD93_RS08055	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GJD93_RS08060	COG4638	Rieske (2fe-2S)
GJD93_RS08070	COG4829	muconolactone delta-isomerase
GJD93_RS08075	COG4948	Mandelate Racemase Muconate Lactonizing
GJD93_RS08080	COG0583	DNA-binding transcription factor activity
GJD93_RS08085	COG2814	Major facilitator Superfamily
GJD93_RS08095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJD93_RS08135	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GJD93_RS08140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJD93_RS08170	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS08205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJD93_RS08210	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GJD93_RS08225	COG2814	Major facilitator Superfamily
GJD93_RS08240	COG1132	(ABC) transporter
GJD93_RS08250	COG2801	Transposase and inactivated derivatives
GJD93_RS08265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GJD93_RS08280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJD93_RS08285	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GJD93_RS08295	COG1944	ATP diphosphatase activity
GJD93_RS08300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJD93_RS08320	COG0642	Histidine kinase
GJD93_RS08325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GJD93_RS08330	COG0511	ligase activity, forming carbon-carbon bonds
GJD93_RS08340	COG0596	Alpha beta hydrolase
GJD93_RS08360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJD93_RS08365	COG1283	sodium-dependent phosphate transmembrane transporter activity
GJD93_RS08415	COG0552	protein localization to endoplasmic reticulum
GJD93_RS08420	COG0612	Peptidase, M16
GJD93_RS08450	COG0517	IMP dehydrogenase activity
GJD93_RS08455	COG0133	tryptophan synthase activity
GJD93_RS08465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GJD93_RS08485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GJD93_RS08515	COG0537	adenosine 5'-monophosphoramidase activity
GJD93_RS08540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJD93_RS08570	COG0822	iron-sulfur transferase activity
GJD93_RS08575	COG0316	Belongs to the HesB IscA family
GJD93_RS08605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GJD93_RS08620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GJD93_RS08625	COG0702	epimerase
GJD93_RS08630	COG0268	Binds directly to 16S ribosomal RNA
GJD93_RS08660	COG1011	Hydrolase
GJD93_RS08665	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GJD93_RS08675	COG2137	regulation of response to DNA damage stimulus
GJD93_RS08690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD93_RS08700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GJD93_RS08710	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GJD93_RS08725	COG0575	Belongs to the CDS family
GJD93_RS08730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GJD93_RS08750	COG3852	Histidine kinase
GJD93_RS08765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJD93_RS08770	COG0583	DNA-binding transcription factor activity
GJD93_RS08775	COG2963	transposase activity
GJD93_RS08785	COG4372	Transposase
GJD93_RS08790	COG0024	Methionine aminopeptidase
GJD93_RS08805	COG1114	Component of the transport system for branched-chain amino acids
GJD93_RS08825	COG1253	flavin adenine dinucleotide binding
GJD93_RS08845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GJD93_RS08850	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GJD93_RS08865	COG2431	L-lysine efflux transmembrane transporter activity
GJD93_RS08910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GJD93_RS08945	COG0084	hydrolase, TatD family'
GJD93_RS08965	COG1663	tetraacyldisaccharide 4'-kinase activity
GJD93_RS08970	COG1132	(ABC) transporter
GJD93_RS08980	COG0811	peptide transport
GJD93_RS08985	COG1475	DNA binding
GJD93_RS08990	COG1192	Involved in chromosome partitioning
GJD93_RS09000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GJD93_RS09015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJD93_RS09020	COG1923	regulation of RNA biosynthetic process
GJD93_RS09030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GJD93_RS09035	COG0802	atpase or kinase
GJD93_RS09060	COG2707	UPF0756 membrane protein
GJD93_RS09065	COG2807	transmembrane transport
GJD93_RS09070	COG0583	DNA-binding transcription factor activity
GJD93_RS09075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJD93_RS09080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJD93_RS09090	COG1454	alcohol dehydrogenase
GJD93_RS09110	COG2353	YceI-like domain
GJD93_RS09125	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GJD93_RS09130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GJD93_RS09170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GJD93_RS09170	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GJD93_RS09200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GJD93_RS09315	COG0012	GTP binding
GJD93_RS09325	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GJD93_RS09335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GJD93_RS09340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GJD93_RS09350	COG0386	Belongs to the glutathione peroxidase family
GJD93_RS09355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJD93_RS09360	COG0436	Aminotransferase
GJD93_RS09395	COG2815	serine threonine protein kinase
GJD93_RS09395	COG0515	serine threonine protein kinase
GJD93_RS09430	COG1610	YqeY-like protein
GJD93_RS09445	COG4783	chaperone-mediated protein folding
GJD93_RS09470	COG1286	toxin biosynthetic process
GJD93_RS09475	COG0167	dihydroorotate dehydrogenase activity
GJD93_RS09500	COG0778	Nitroreductase
GJD93_RS09510	COG0513	Belongs to the DEAD box helicase family
GJD93_RS09515	COG1278	Cold shock
GJD93_RS09530	COG2363	Small membrane protein
GJD93_RS09550	COG0659	secondary active sulfate transmembrane transporter activity
GJD93_RS09555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GJD93_RS09580	COG0318	PFAM AMP-dependent synthetase and ligase
GJD93_RS09585	COG1309	transcriptional regulator
GJD93_RS09590	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS09595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GJD93_RS09600	COG1024	Enoyl-CoA hydratase
GJD93_RS09605	COG4770	biotin carboxylase activity
GJD93_RS09620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GJD93_RS09625	COG2885	chlorophyll binding
GJD93_RS09625	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GJD93_RS09645	COG0540	Belongs to the ATCase OTCase family
GJD93_RS09670	COG1765	OsmC-like protein
GJD93_RS09680	COG0667	Aldo Keto reductase
GJD93_RS09695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GJD93_RS09710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GJD93_RS09715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GJD93_RS09720	COG0527	aspartate kinase activity
GJD93_RS09730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GJD93_RS09745	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GJD93_RS09750	COG2252	PERMEase
GJD93_RS09780	COG0714	Associated with various cellular activities
GJD93_RS09785	COG2879	small protein
GJD93_RS09790	COG1966	Carbon starvation protein
GJD93_RS09795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GJD93_RS09800	COG1509	lysine 2,3-aminomutase activity
GJD93_RS09835	COG1067	ATP-dependent peptidase activity
GJD93_RS09840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GJD93_RS09845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GJD93_RS09850	COG0583	DNA-binding transcription factor activity
GJD93_RS09875	COG1686	Belongs to the peptidase S11 family
GJD93_RS09880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GJD93_RS09910	COG2915	High frequency lysogenization protein hflD homolog
GJD93_RS09935	COG0616	signal peptide processing
GJD93_RS09945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJD93_RS09955	COG0573	inorganic phosphate transmembrane transporter activity
GJD93_RS09965	COG0076	glutamate decarboxylase activity
GJD93_RS09970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GJD93_RS09980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GJD93_RS09995	COG2814	Major facilitator Superfamily
GJD93_RS10000	COG1733	regulation of RNA biosynthetic process
GJD93_RS10020	COG0556	nucleotide-excision repair
GJD93_RS10035	COG0436	Aminotransferase
GJD93_RS10060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GJD93_RS10075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GJD93_RS10080	COG0571	ribonuclease III activity
GJD93_RS10105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJD93_RS10115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJD93_RS10130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GJD93_RS10140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GJD93_RS10155	COG4208	sulfate ABC transporter
GJD93_RS10160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GJD93_RS10165	COG0583	DNA-binding transcription factor activity
GJD93_RS10175	COG4625	pathogenesis
GJD93_RS10190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GJD93_RS10200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GJD93_RS10205	COG1051	belongs to the nudix hydrolase family
GJD93_RS10205	COG1056	cytidyltransferase-related domain
GJD93_RS10210	COG1024	Enoyl-CoA hydratase
GJD93_RS10215	COG0778	Nitroreductase
GJD93_RS10230	COG0632	four-way junction helicase activity
GJD93_RS10235	COG2255	four-way junction helicase activity
GJD93_RS10245	COG0824	Thioesterase
GJD93_RS10265	COG0823	Involved in the tonB-independent uptake of proteins
GJD93_RS10290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJD93_RS10320	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GJD93_RS10325	COG0628	permease
GJD93_RS10330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GJD93_RS10335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GJD93_RS10355	COG2333	competence protein COMEC
GJD93_RS10355	COG0658	competence protein
GJD93_RS10360	COG1136	(ABC) transporter
GJD93_RS10365	COG4591	ABC-type transport system involved in lipoprotein release permease component
GJD93_RS10380	COG1671	Belongs to the UPF0178 family
GJD93_RS10415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD93_RS10470	COG0019	diaminopimelate decarboxylase activity
GJD93_RS10480	COG1115	amino acid carrier protein
GJD93_RS10495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJD93_RS10500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GJD93_RS10505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GJD93_RS10540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GJD93_RS10550	COG0174	glutamine synthetase
GJD93_RS10555	COG0512	Glutamine amidotransferase of anthranilate synthase
GJD93_RS10560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GJD93_RS10575	COG0302	gtp cyclohydrolase
GJD93_RS10580	COG3706	GGDEF domain
GJD93_RS10595	COG3739	integral membrane protein
GJD93_RS10610	COG1741	Belongs to the pirin family
GJD93_RS10615	COG2072	flavoprotein involved in K transport
GJD93_RS10630	COG2871	sodium ion transport
GJD93_RS10700	COG0175	sulfate reduction
GJD93_RS10710	COG3549	Plasmid maintenance system killer
GJD93_RS10715	COG3093	addiction module antidote protein HigA
GJD93_RS10730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJD93_RS10735	COG1773	rubredoxin
GJD93_RS10740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GJD93_RS10745	COG2267	carboxylic ester hydrolase activity
GJD93_RS10750	COG0583	DNA-binding transcription factor activity
GJD93_RS10765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJD93_RS10770	COG0705	Rhomboid family
GJD93_RS10770	COG0457	Tetratricopeptide repeat
GJD93_RS10775	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GJD93_RS10780	COG4181	ATPase activity
GJD93_RS10825	COG0306	phosphate transporter
GJD93_RS10845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GJD93_RS10870	COG0739	heme binding
GJD93_RS10870	COG1196	nuclear chromosome segregation
GJD93_RS10870	COG0741	lytic transglycosylase activity
GJD93_RS10875	COG0501	Belongs to the peptidase M48B family
GJD93_RS10885	COG2239	Acts as a magnesium transporter
GJD93_RS10905	COG0459	protein refolding
GJD93_RS10920	COG1597	lipid kinase activity
GJD93_RS10945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GJD93_RS10985	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GJD93_RS10990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GJD93_RS11015	COG0505	Belongs to the CarA family
GJD93_RS11040	COG0589	response to stress
GJD93_RS11045	COG3695	enzyme binding
GJD93_RS11050	COG2321	neutral zinc metallopeptidase
GJD93_RS11055	COG2354	Protein conserved in bacteria
GJD93_RS11075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD93_RS11090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GJD93_RS11095	COG1053	succinate dehydrogenase
GJD93_RS11100	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GJD93_RS11120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GJD93_RS11120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GJD93_RS11145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GJD93_RS11170	COG0564	pseudouridine synthase activity
GJD93_RS11180	COG0358	DNA primase activity
GJD93_RS11185	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GJD93_RS11195	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GJD93_RS11210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJD93_RS11235	COG1054	Belongs to the UPF0176 family
GJD93_RS11245	COG0586	Pfam SNARE associated Golgi protein
GJD93_RS11280	COG0321	lipoyl(octanoyl) transferase activity
GJD93_RS11295	COG0531	amino acid
GJD93_RS11300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GJD93_RS11305	COG1648	precorrin-2 dehydrogenase activity
GJD93_RS11305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GJD93_RS11310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GJD93_RS11320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GJD93_RS11345	COG0671	phosphoesterase, PA-phosphatase related
GJD93_RS11350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJD93_RS11360	COG1538	Outer membrane efflux protein
GJD93_RS11365	COG0393	Putative heavy-metal-binding
GJD93_RS11370	COG0393	Putative heavy-metal-binding
GJD93_RS11380	COG3328	transposase activity
GJD93_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
GJD93_RS11395	COG0525	valine-tRNA ligase activity
GJD93_RS11410	COG2323	membrane
GJD93_RS11425	COG1752	Esterase of the alpha-beta hydrolase superfamily
GJD93_RS11440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GJD93_RS11445	COG2205	protein histidine kinase activity
GJD93_RS11450	COG0745	RESPONSE REGULATOR receiver
GJD93_RS11460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJD93_RS11470	COG1652	LysM domain
GJD93_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
GJD93_RS11495	COG1399	metal-binding, possibly nucleic acid-binding protein
GJD93_RS11500	COG3101	peptidyl-lysine hydroxylation
GJD93_RS11505	COG0009	L-threonylcarbamoyladenylate synthase
GJD93_RS11515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GJD93_RS11520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GJD93_RS11535	COG4106	trans-aconitate 2-methyltransferase activity
GJD93_RS11550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GJD93_RS11550	COG2226	methyltransferase
GJD93_RS11550	COG0596	Alpha beta hydrolase
GJD93_RS11555	COG2193	ferroxidase activity
GJD93_RS11560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GJD93_RS11565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GJD93_RS11570	COG3115	cell septum assembly
GJD93_RS11575	COG1196	nuclear chromosome segregation
GJD93_RS11585	COG0730	response to heat
GJD93_RS11600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GJD93_RS11615	COG5342	invasion associated locus B
GJD93_RS11620	COG3422	double-strand break repair
GJD93_RS11625	COG2824	Alkylphosphonate utilization operon protein PhnA
GJD93_RS11630	COG3189	MarR family transcriptional regulator
GJD93_RS11645	COG0564	pseudouridine synthase activity
GJD93_RS11670	COG1487	ribonuclease activity
GJD93_RS11675	COG4456	Virulence-associated protein
GJD93_RS11680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GJD93_RS11705	COG1902	pentaerythritol trinitrate reductase activity
GJD93_RS11715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJD93_RS11720	COG1970	mechanosensitive ion channel activity
GJD93_RS11725	COG1217	gtp-binding protein TYPA
GJD93_RS11730	COG2233	PERMEase
GJD93_RS11740	COG0833	amino acid
GJD93_RS11755	COG0183	Belongs to the thiolase family
GJD93_RS11770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GJD93_RS11775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GJD93_RS11780	COG2207	Transcriptional regulator
GJD93_RS11785	COG0183	Belongs to the thiolase family
GJD93_RS11790	COG1024	Enoyl-CoA hydratase
GJD93_RS11790	COG1250	3-hydroxyacyl-CoA dehydrogenase
GJD93_RS11810	COG1272	protein, Hemolysin III
GJD93_RS11815	COG0477	Major facilitator Superfamily
GJD93_RS11820	COG1408	metallophosphoesterase
GJD93_RS11825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJD93_RS11835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GJD93_RS11865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GJD93_RS11870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GJD93_RS11890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GJD93_RS11895	COG0625	glutathione transferase activity
GJD93_RS11900	COG2969	positive regulation of protein catabolic process
GJD93_RS11940	COG5001	Diguanylate cyclase
GJD93_RS11940	COG3300	MHYT domain
GJD93_RS11945	COG2885	chlorophyll binding
GJD93_RS11970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GJD93_RS11975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GJD93_RS11990	COG0450	alkyl hydroperoxide reductase
GJD93_RS12000	COG0285	dihydrofolate synthase activity
GJD93_RS12005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GJD93_RS12025	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GJD93_RS12030	COG1162	GTPase activity
GJD93_RS12040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GJD93_RS12050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GJD93_RS12060	COG3781	membrane
GJD93_RS12075	COG2350	Protein conserved in bacteria
GJD93_RS12105	COG1607	acyl-coa hydrolase
GJD93_RS12135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJD93_RS12170	COG1183	phosphatidylcholine synthase activity
GJD93_RS12175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GJD93_RS12200	COG2391	methyltransferase activity
GJD93_RS12215	COG0741	lytic transglycosylase activity
GJD93_RS12215	COG1196	nuclear chromosome segregation
GJD93_RS12215	COG0739	heme binding
GJD93_RS12220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GJD93_RS12225	COG1702	phosphate starvation-inducible protein PhoH
GJD93_RS12230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GJD93_RS12270	COG1295	ribonuclease BN
GJD93_RS12295	COG0788	formyltetrahydrofolate deformylase activity
GJD93_RS12320	COG4651	solute:proton antiporter activity
GJD93_RS12320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GJD93_RS12335	COG0724	RNA recognition motif
GJD93_RS12370	COG2900	Belongs to the SlyX family
GJD93_RS12375	COG0488	(ABC) transporter
GJD93_RS12380	COG1560	Kdo2-lipid A biosynthetic process
GJD93_RS12410	COG0252	asparaginase activity
GJD93_RS12415	COG0101	tRNA pseudouridine synthase activity
GJD93_RS12435	COG0473	3-isopropylmalate dehydrogenase activity
GJD93_RS12450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GJD93_RS12465	COG0583	DNA-binding transcription factor activity
GJD93_RS12500	COG1960	acyl-CoA dehydrogenase activity
GJD93_RS12510	COG0753	catalase activity
GJD93_RS12525	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJD93_RS12530	COG3384	dioxygenase
GJD93_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
GJD93_RS12550	COG4638	Rieske (2fe-2S)
GJD93_RS12555	COG0583	DNA-binding transcription factor activity
GJD93_RS12580	COG4569	acetaldehyde dehydrogenase (acetylating) activity
GJD93_RS12585	COG3971	2-oxopent-4-enoate hydratase activity
GJD93_RS12590	COG0546	phosphoglycolate phosphatase activity
GJD93_RS12600	COG1530	ribonuclease E activity
GJD93_RS12605	COG0318	PFAM AMP-dependent synthetase and ligase
GJD93_RS12630	COG1983	PspC domain protein
GJD93_RS12635	COG0517	IMP dehydrogenase activity
GJD93_RS12645	COG0751	glycine-tRNA ligase activity
GJD93_RS12675	COG2226	methyltransferase
GJD93_RS12685	COG0493	'glutamate synthase
GJD93_RS12695	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GJD93_RS12700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GJD93_RS12715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GJD93_RS12725	COG0644	oxidoreductase
GJD93_RS12725	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GJD93_RS12750	COG4535	Mg2 and Co2 transporter CorC
GJD93_RS12755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GJD93_RS12770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GJD93_RS12780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GJD93_RS12820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJD93_RS12825	COG1074	ATP-dependent DNA helicase activity
GJD93_RS12830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GJD93_RS12850	COG2226	methyltransferase
GJD93_RS12860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GJD93_RS12885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GJD93_RS12885	COG2111	Na H antiporter
GJD93_RS12890	COG1006	Multisubunit Na H antiporter MnhC subunit
GJD93_RS12895	COG0651	ATP synthesis coupled electron transport
GJD93_RS12900	COG1863	multisubunit Na H antiporter MnhE subunit
GJD93_RS12905	COG2212	antiporter activity
GJD93_RS12910	COG1320	monovalent cation:proton antiporter activity
GJD93_RS12915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GJD93_RS12920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GJD93_RS12925	COG0195	Participates in both transcription termination and antitermination
GJD93_RS12930	COG0779	Required for maturation of 30S ribosomal subunits
GJD93_RS12980	COG0237	dephospho-CoA kinase activity
GJD93_RS12990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJD93_RS12995	COG3123	guanosine phosphorylase activity
GJD93_RS13000	COG0497	DNA recombination
GJD93_RS13030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GJD93_RS13045	COG1132	(ABC) transporter
GJD93_RS13050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GJD93_RS13060	COG0322	excinuclease ABC activity
GJD93_RS13080	COG1250	3-hydroxyacyl-CoA dehydrogenase
GJD93_RS13080	COG1024	Enoyl-CoA hydratase
GJD93_RS13100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GJD93_RS13125	COG0326	Molecular chaperone. Has ATPase activity
GJD93_RS13140	COG2056	Na+-H+ antiporter family
GJD93_RS13175	COG0085	RNA polymerase activity
GJD93_RS13190	COG0081	regulation of translation
GJD93_RS13275	COG0824	Thioesterase
GJD93_RS13295	COG0181	hydroxymethylbilane synthase activity
GJD93_RS13305	COG3275	phosphorelay sensor kinase activity
GJD93_RS13325	COG1538	Outer membrane efflux protein
GJD93_RS13340	COG0494	nUDIX hydrolase
GJD93_RS13345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GJD93_RS13350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GJD93_RS13355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GJD93_RS13365	COG0772	Belongs to the SEDS family
GJD93_RS13390	COG4974	Belongs to the 'phage' integrase family
GJD93_RS13395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GJD93_RS13405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GJD93_RS13415	COG2197	response regulator
GJD93_RS13430	COG0793	Belongs to the peptidase S41A family
GJD93_RS13435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GJD93_RS13440	COG0795	lipopolysaccharide-transporting ATPase activity
GJD93_RS13445	COG0795	lipopolysaccharide-transporting ATPase activity
GJD93_RS13470	COG0586	Pfam SNARE associated Golgi protein
GJD93_RS13485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GJD93_RS13485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GJD93_RS13495	COG0004	ammonium transporteR
GJD93_RS13500	COG0347	Belongs to the P(II) protein family
GJD93_RS13510	COG0606	chelatase, subunit chli
GJD93_RS13525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GJD93_RS13540	COG0318	PFAM AMP-dependent synthetase and ligase
GJD93_RS13555	COG0477	Major facilitator Superfamily
GJD93_RS13560	COG2860	membrane
GJD93_RS13565	COG3012	SEC-C Motif Domain Protein
GJD93_RS13570	COG1253	flavin adenine dinucleotide binding
GJD93_RS13605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJD93_RS13625	COG2814	Major facilitator Superfamily
GJD93_RS13630	COG2814	Major facilitator Superfamily
GJD93_RS13680	COG0758	DNA mediated transformation
GJD93_RS13695	COG3547	Transposase (IS116 IS110 IS902 family)
GJD93_RS13710	COG0697	spore germination
GJD93_RS13715	COG0386	Belongs to the glutathione peroxidase family
GJD93_RS13730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GJD93_RS13780	COG1121	(ABC) transporter
GJD93_RS13785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJD93_RS13800	COG2837	iron assimilation
GJD93_RS13810	COG3179	chitinase
GJD93_RS13860	COG2814	Major facilitator Superfamily
GJD93_RS13870	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GJD93_RS13870	COG0352	thiamine-phosphate diphosphorylase activity
GJD93_RS13870	COG0351	phosphomethylpyrimidine kinase
GJD93_RS13895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GJD93_RS13900	COG3162	membrane
GJD93_RS13905	COG2205	protein histidine kinase activity
GJD93_RS13905	COG0784	Response regulator, receiver
GJD93_RS13915	COG0281	malic enzyme
GJD93_RS13955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GJD93_RS13955	COG0519	Catalyzes the synthesis of GMP from XMP
GJD93_RS13960	COG2259	Doxx family
GJD93_RS13965	COG0586	Pfam SNARE associated Golgi protein
GJD93_RS13980	COG1192	Involved in chromosome partitioning
GJD93_RS13985	COG3094	Invasion gene expression up-regulator, SirB
GJD93_RS13990	COG0271	Belongs to the BolA IbaG family
GJD93_RS14010	COG3550	peptidyl-serine autophosphorylation
GJD93_RS14015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GJD93_RS14025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJD93_RS14030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJD93_RS14045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GJD93_RS14055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GJD93_RS14065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GJD93_RS14075	COG0438	transferase activity, transferring glycosyl groups
GJD93_RS14085	COG0438	transferase activity, transferring glycosyl groups
GJD93_RS14095	COG2244	polysaccharide biosynthetic process
GJD93_RS14105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GJD93_RS14115	COG2089	acid synthase
GJD93_RS14120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GJD93_RS14125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GJD93_RS14135	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GJD93_RS14140	COG1596	polysaccharide export
GJD93_RS14160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GJD93_RS14190	COG1309	transcriptional regulator
GJD93_RS14200	COG3706	GGDEF domain
GJD93_RS14205	COG2233	PERMEase
GJD93_RS14225	COG0129	dihydroxy-acid dehydratase activity
GJD93_RS14230	COG0129	dihydroxy-acid dehydratase activity
GJD93_RS14240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJD93_RS14250	COG0733	neurotransmitter:sodium symporter activity
GJD93_RS14255	COG1012	belongs to the aldehyde dehydrogenase family
GJD93_RS14290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GJD93_RS14300	COG0657	acetylesterase activity
GJD93_RS14310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GJD93_RS14330	COG2951	lytic endotransglycosylase activity
GJD93_RS14335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GJD93_RS14350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GJD93_RS14355	COG1063	alcohol dehydrogenase
GJD93_RS14365	COG0861	Integral membrane protein TerC family
GJD93_RS14370	COG0402	S-adenosylhomocysteine deaminase activity
GJD93_RS14390	COG1230	cation diffusion facilitator family transporter
GJD93_RS14415	COG0706	membrane insertase activity
GJD93_RS14420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GJD93_RS14425	COG0594	ribonuclease P activity