locus-tag	class	description
IAQ69_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAQ69_RS00010	COG0592	DNA-directed DNA polymerase activity
IAQ69_RS00020	COG0187	DNA topoisomerase II activity
IAQ69_RS00030	COG1063	alcohol dehydrogenase
IAQ69_RS00040	COG0488	(ABC) transporter
IAQ69_RS00065	COG3385	transposase activity
IAQ69_RS00100	COG0657	acetylesterase activity
IAQ69_RS00110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAQ69_RS00140	COG4251	negative regulation of phosphorylation
IAQ69_RS00140	COG5001	Diguanylate cyclase
IAQ69_RS00140	COG2203	Gaf domain
IAQ69_RS00140	COG3706	GGDEF domain
IAQ69_RS00145	COG2133	pyrroloquinoline quinone binding
IAQ69_RS00160	COG1047	Peptidyl-prolyl cis-trans
IAQ69_RS00170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAQ69_RS00175	COG0196	riboflavin kinase activity
IAQ69_RS00185	COG1309	transcriptional regulator
IAQ69_RS00190	COG1116	anion transmembrane transporter activity
IAQ69_RS00195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_RS00200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ69_RS00205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_RS00210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_RS00215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IAQ69_RS00215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAQ69_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_RS00245	COG0546	phosphoglycolate phosphatase activity
IAQ69_RS00250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAQ69_RS00255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAQ69_RS00260	COG1309	transcriptional regulator
IAQ69_RS00265	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IAQ69_RS00275	COG3023	N-Acetylmuramoyl-L-alanine amidase
IAQ69_RS00285	COG5487	UPF0391 membrane protein
IAQ69_RS00290	COG2983	Belongs to the UPF0260 family
IAQ69_RS00295	COG5001	Diguanylate cyclase
IAQ69_RS00295	COG3300	MHYT domain
IAQ69_RS00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAQ69_RS00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IAQ69_RS00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAQ69_RS00340	COG1335	isochorismatase
IAQ69_RS00345	COG0385	Bile acid
IAQ69_RS00355	COG0560	Phosphoserine phosphatase
IAQ69_RS00355	COG3830	Belongs to the UPF0237 family
IAQ69_RS00375	COG0753	catalase activity
IAQ69_RS00415	COG2733	membrane
IAQ69_RS00430	COG2918	glutathione biosynthetic process
IAQ69_RS00435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAQ69_RS00445	COG3150	esterase
IAQ69_RS00495	COG3706	GGDEF domain
IAQ69_RS00500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAQ69_RS00515	COG1393	Belongs to the ArsC family
IAQ69_RS00520	COG0708	Exodeoxyribonuclease III
IAQ69_RS00540	COG0189	ligase activity
IAQ69_RS00555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAQ69_RS00565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAQ69_RS00575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAQ69_RS00605	COG2119	membrane
IAQ69_RS00610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ69_RS00610	COG0426	domain, Protein
IAQ69_RS00640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAQ69_RS00670	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_RS00675	COG1519	Transferase
IAQ69_RS00680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAQ69_RS00685	COG0668	transmembrane transport
IAQ69_RS00695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAQ69_RS00710	COG0307	riboflavin synthase, alpha
IAQ69_RS00720	COG0431	NADPH-dependent FMN reductase
IAQ69_RS00735	COG0784	Response regulator, receiver
IAQ69_RS00735	COG2198	Histidine kinase
IAQ69_RS00735	COG2205	protein histidine kinase activity
IAQ69_RS00740	COG3162	membrane
IAQ69_RS00745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAQ69_RS00755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAQ69_RS00770	COG3706	GGDEF domain
IAQ69_RS00775	COG0537	adenosine 5'-monophosphoramidase activity
IAQ69_RS00785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAQ69_RS00785	COG0351	phosphomethylpyrimidine kinase
IAQ69_RS00785	COG0352	thiamine-phosphate diphosphorylase activity
IAQ69_RS00800	COG2814	Major facilitator Superfamily
IAQ69_RS00805	COG0629	single-stranded DNA binding
IAQ69_RS00860	COG3158	transport of potassium into the cell
IAQ69_RS00895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAQ69_RS00925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAQ69_RS00980	COG0183	Belongs to the thiolase family
IAQ69_RS00985	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_RS00985	COG1024	Enoyl-CoA hydratase
IAQ69_RS01015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAQ69_RS01030	COG3275	phosphorelay sensor kinase activity
IAQ69_RS01040	COG0181	hydroxymethylbilane synthase activity
IAQ69_RS01060	COG0824	Thioesterase
IAQ69_RS01085	COG1716	ATPase activity
IAQ69_RS01090	COG0546	phosphoglycolate phosphatase activity
IAQ69_RS01150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAQ69_RS01165	COG0085	RNA polymerase activity
IAQ69_RS01170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAQ69_RS01190	COG2056	Na+-H+ antiporter family
IAQ69_RS01195	COG3047	cAMP biosynthetic process
IAQ69_RS01205	COG0326	Molecular chaperone. Has ATPase activity
IAQ69_RS01240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAQ69_RS01245	COG0427	acetyl-CoA hydrolase
IAQ69_RS01285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAQ69_RS01295	COG2226	methyltransferase
IAQ69_RS01315	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IAQ69_RS01320	COG1074	ATP-dependent DNA helicase activity
IAQ69_RS01325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAQ69_RS01330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAQ69_RS01340	COG2841	Protein conserved in bacteria
IAQ69_RS01345	COG0789	Transcriptional regulator
IAQ69_RS01365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAQ69_RS01375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAQ69_RS01405	COG4535	Mg2 and Co2 transporter CorC
IAQ69_RS01430	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAQ69_RS01430	COG0644	oxidoreductase
IAQ69_RS01440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAQ69_RS01455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ69_RS01465	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IAQ69_RS01475	COG0644	oxidoreductase
IAQ69_RS01485	COG2226	methyltransferase
IAQ69_RS01500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAQ69_RS01525	COG0751	glycine-tRNA ligase activity
IAQ69_RS01530	COG0752	glycyl-tRNA synthetase alpha subunit
IAQ69_RS01540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IAQ69_RS01540	COG0617	tRNA 3'-terminal CCA addition
IAQ69_RS01540	COG0517	IMP dehydrogenase activity
IAQ69_RS01545	COG0471	metal ion transport
IAQ69_RS01555	COG1983	PspC domain protein
IAQ69_RS01580	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_RS01585	COG1530	ribonuclease E activity
IAQ69_RS01595	COG0546	phosphoglycolate phosphatase activity
IAQ69_RS01600	COG3971	2-oxopent-4-enoate hydratase activity
IAQ69_RS01605	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IAQ69_RS01625	COG0583	DNA-binding transcription factor activity
IAQ69_RS01630	COG4638	Rieske (2fe-2S)
IAQ69_RS01645	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_RS01650	COG3384	dioxygenase
IAQ69_RS01655	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ69_RS01665	COG0519	Catalyzes the synthesis of GMP from XMP
IAQ69_RS01685	COG0753	catalase activity
IAQ69_RS01735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAQ69_RS01750	COG0473	3-isopropylmalate dehydrogenase activity
IAQ69_RS01810	COG1560	Kdo2-lipid A biosynthetic process
IAQ69_RS01815	COG0488	(ABC) transporter
IAQ69_RS01820	COG2900	Belongs to the SlyX family
IAQ69_RS01860	COG1929	Belongs to the glycerate kinase type-1 family
IAQ69_RS01865	COG0210	DNA helicase
IAQ69_RS01870	COG0724	RNA recognition motif
IAQ69_RS01885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAQ69_RS01885	COG4651	solute:proton antiporter activity
IAQ69_RS01910	COG0788	formyltetrahydrofolate deformylase activity
IAQ69_RS01945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAQ69_RS01955	COG3040	lipid binding
IAQ69_RS02000	COG2813	Specifically methylates the guanine in position
IAQ69_RS02000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAQ69_RS02005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAQ69_RS02010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAQ69_RS02015	COG4774	siderophore transport
IAQ69_RS02025	COG3128	pkhd-type hydroxylase
IAQ69_RS02030	COG4774	siderophore transport
IAQ69_RS02035	COG4774	siderophore transport
IAQ69_RS02045	COG0740	serine-type endopeptidase activity
IAQ69_RS02065	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IAQ69_RS02065	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAQ69_RS02075	COG0280	phosphate acetyltransferase
IAQ69_RS02075	COG0857	belongs to the CobB CobQ family
IAQ69_RS02080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAQ69_RS02105	COG0793	Belongs to the peptidase S41A family
IAQ69_RS02115	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAQ69_RS02130	COG0084	hydrolase, TatD family'
IAQ69_RS02160	COG1162	GTPase activity
IAQ69_RS02165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IAQ69_RS02175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAQ69_RS02185	COG1538	Outer membrane efflux protein
IAQ69_RS02190	COG0577	efflux transmembrane transporter activity
IAQ69_RS02190	COG1136	(ABC) transporter
IAQ69_RS02195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_RS02200	COG2703	oxygen carrier activity
IAQ69_RS02225	COG0028	Belongs to the TPP enzyme family
IAQ69_RS02245	COG2975	iron-sulfur cluster assembly
IAQ69_RS02265	COG1426	Protein conserved in bacteria
IAQ69_RS02315	COG4221	oxidoreductase activity
IAQ69_RS02320	COG3956	TIGRFAM MazG family protein
IAQ69_RS02325	COG1555	photosystem II stabilization
IAQ69_RS02325	COG1596	polysaccharide export
IAQ69_RS02330	COG0617	tRNA 3'-terminal CCA addition
IAQ69_RS02335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAQ69_RS02350	COG1660	Displays ATPase and GTPase activities
IAQ69_RS02365	COG2205	protein histidine kinase activity
IAQ69_RS02370	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IAQ69_RS02430	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IAQ69_RS02475	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS02480	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS02490	COG2205	protein histidine kinase activity
IAQ69_RS02495	COG0745	RESPONSE REGULATOR receiver
IAQ69_RS02505	COG1113	amino acid transport
IAQ69_RS02515	COG2315	Protein conserved in bacteria
IAQ69_RS02520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IAQ69_RS02535	COG2096	Adenosyltransferase
IAQ69_RS02540	COG4206	TonB-dependent receptor
IAQ69_RS02585	COG0285	dihydrofolate synthase activity
IAQ69_RS02600	COG0450	alkyl hydroperoxide reductase
IAQ69_RS02615	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAQ69_RS02620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IAQ69_RS02700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IAQ69_RS02705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAQ69_RS02750	COG3385	transposase activity
IAQ69_RS02760	COG0494	nUDIX hydrolase
IAQ69_RS02770	COG1214	PFAM Peptidase M22, glycoprotease
IAQ69_RS02775	COG1968	undecaprenyl-diphosphatase activity
IAQ69_RS02790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IAQ69_RS02795	COG4269	membrane
IAQ69_RS02805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAQ69_RS02815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAQ69_RS02830	COG2814	Major facilitator Superfamily
IAQ69_RS02835	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_RS02835	COG2030	dehydratase
IAQ69_RS02840	COG3293	Transposase
IAQ69_RS02845	COG3396	Phenylacetate-CoA oxygenase
IAQ69_RS02850	COG3460	Phenylacetate-CoA oxygenase
IAQ69_RS02855	COG3396	Phenylacetate-CoA oxygenase
IAQ69_RS02860	COG2151	metal-sulfur cluster biosynthetic enzyme
IAQ69_RS02865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAQ69_RS02870	COG1024	Enoyl-CoA hydratase
IAQ69_RS02875	COG0183	Belongs to the thiolase family
IAQ69_RS02880	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IAQ69_RS02885	COG3327	negative regulation of DNA-templated transcription, initiation
IAQ69_RS02905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAQ69_RS02915	COG3545	Serine hydrolase
IAQ69_RS02930	COG0730	response to heat
IAQ69_RS02940	COG1196	nuclear chromosome segregation
IAQ69_RS02950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAQ69_RS02955	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IAQ69_RS02960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAQ69_RS02965	COG2193	ferroxidase activity
IAQ69_RS02985	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IAQ69_RS02995	COG4166	transmembrane transport
IAQ69_RS03005	COG0339	signal peptide processing
IAQ69_RS03035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAQ69_RS03040	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAQ69_RS03055	COG0009	L-threonylcarbamoyladenylate synthase
IAQ69_RS03060	COG3101	peptidyl-lysine hydroxylation
IAQ69_RS03065	COG1399	metal-binding, possibly nucleic acid-binding protein
IAQ69_RS03070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IAQ69_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_RS03085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAQ69_RS03090	COG1652	LysM domain
IAQ69_RS03110	COG0251	oxidation-reduction process
IAQ69_RS03115	COG1113	amino acid transport
IAQ69_RS03120	COG1981	membrane
IAQ69_RS03135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAQ69_RS03145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAQ69_RS03160	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_RS03165	COG0456	acetyltransferase
IAQ69_RS03175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IAQ69_RS03180	COG0492	ferredoxin-NADP+ reductase activity
IAQ69_RS03185	COG0531	amino acid
IAQ69_RS03185	COG1674	ftsk spoiiie
IAQ69_RS03205	COG0850	regulation of cytokinetic process
IAQ69_RS03215	COG0204	Acyl-transferase
IAQ69_RS03220	COG2885	chlorophyll binding
IAQ69_RS03230	COG0756	dUTP diphosphatase activity
IAQ69_RS03245	COG0121	glutamine amidotransferase
IAQ69_RS03260	COG2914	Belongs to the UPF0125 (RnfH) family
IAQ69_RS03265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAQ69_RS03270	COG0735	belongs to the Fur family
IAQ69_RS03300	COG0420	3'-5' exonuclease activity
IAQ69_RS03310	COG1090	epimerase
IAQ69_RS03315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAQ69_RS03325	COG2050	protein possibly involved in aromatic compounds catabolism
IAQ69_RS03330	COG1566	PFAM secretion protein HlyD family protein
IAQ69_RS03335	COG2814	Major facilitator Superfamily
IAQ69_RS03340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAQ69_RS03450	COG0443	Heat shock 70 kDa protein
IAQ69_RS03455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ69_RS03470	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_RS03475	COG0129	dihydroxy-acid dehydratase activity
IAQ69_RS03485	COG0583	DNA-binding transcription factor activity
IAQ69_RS03495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAQ69_RS03505	COG2084	Dehydrogenase
IAQ69_RS03510	COG2814	Major facilitator Superfamily
IAQ69_RS03515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAQ69_RS03520	COG2186	Transcriptional regulator
IAQ69_RS03540	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_RS03565	COG0604	alcohol dehydrogenase
IAQ69_RS03570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_RS03585	COG0625	glutathione transferase activity
IAQ69_RS03610	COG1448	Aminotransferase
IAQ69_RS03615	COG1113	amino acid transport
IAQ69_RS03630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAQ69_RS03635	COG0596	Alpha beta hydrolase
IAQ69_RS03650	COG4106	trans-aconitate 2-methyltransferase activity
IAQ69_RS03675	COG0583	DNA-binding transcription factor activity
IAQ69_RS03690	COG2223	nitrite transmembrane transporter activity
IAQ69_RS03695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_RS03700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_RS03705	COG0243	molybdopterin cofactor binding
IAQ69_RS03715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAQ69_RS03725	COG0314	molybdopterin synthase activity
IAQ69_RS03730	COG0315	cyclic pyranopterin monophosphate synthase activity
IAQ69_RS03730	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAQ69_RS03735	COG0303	'Molybdopterin
IAQ69_RS03740	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAQ69_RS03745	COG4149	molybdate abc transporter
IAQ69_RS03750	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IAQ69_RS03775	COG0783	Belongs to the Dps family
IAQ69_RS03800	COG0500	methyltransferase
IAQ69_RS03810	COG2223	nitrite transmembrane transporter activity
IAQ69_RS03815	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IAQ69_RS03830	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IAQ69_RS03845	COG3590	peptidase
IAQ69_RS03850	COG3590	peptidase
IAQ69_RS03860	COG0697	spore germination
IAQ69_RS03875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAQ69_RS03885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAQ69_RS03890	COG1077	Cell shape determining protein MreB Mrl
IAQ69_RS03895	COG1792	Involved in formation and maintenance of cell shape
IAQ69_RS03900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IAQ69_RS03905	COG0424	maF-like protein
IAQ69_RS03920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAQ69_RS03930	COG0560	Phosphoserine phosphatase
IAQ69_RS03950	COG1113	amino acid transport
IAQ69_RS03955	COG2828	Protein conserved in bacteria
IAQ69_RS03960	COG0142	geranyltranstransferase activity
IAQ69_RS03965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAQ69_RS03980	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAQ69_RS04005	COG2323	membrane
IAQ69_RS04020	COG2852	Protein conserved in bacteria
IAQ69_RS04035	COG3385	transposase activity
IAQ69_RS04040	COG0525	valine-tRNA ligase activity
IAQ69_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_RS04055	COG2066	Belongs to the glutaminase family
IAQ69_RS04060	COG2376	Dihydroxyacetone kinase
IAQ69_RS04065	COG2852	Protein conserved in bacteria
IAQ69_RS04080	COG0306	phosphate transporter
IAQ69_RS04090	COG4607	ABC-type enterochelin transport system periplasmic component
IAQ69_RS04105	COG4771	TonB-dependent receptor
IAQ69_RS04130	COG4181	ATPase activity
IAQ69_RS04135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IAQ69_RS04145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAQ69_RS04160	COG0583	DNA-binding transcription factor activity
IAQ69_RS04170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_RS04175	COG1773	rubredoxin
IAQ69_RS04180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAQ69_RS04210	COG2354	Protein conserved in bacteria
IAQ69_RS04215	COG2321	neutral zinc metallopeptidase
IAQ69_RS04235	COG0589	response to stress
IAQ69_RS04250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IAQ69_RS04250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAQ69_RS04270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IAQ69_RS04275	COG1053	succinate dehydrogenase
IAQ69_RS04280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAQ69_RS04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAQ69_RS04305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAQ69_RS04310	COG2268	Band 7 protein
IAQ69_RS04365	COG3118	belongs to the thioredoxin family
IAQ69_RS04375	COG4221	oxidoreductase activity
IAQ69_RS04375	COG3321	synthase
IAQ69_RS04375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAQ69_RS04375	COG0604	alcohol dehydrogenase
IAQ69_RS04400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAQ69_RS04415	COG0477	Major facilitator Superfamily
IAQ69_RS04425	COG1597	lipid kinase activity
IAQ69_RS04495	COG0742	ribosomal rna small subunit methyltransferase
IAQ69_RS04500	COG0768	penicillin binding
IAQ69_RS04525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAQ69_RS04530	COG2878	Part of a membrane complex involved in electron transport
IAQ69_RS04535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAQ69_RS04545	COG3384	dioxygenase
IAQ69_RS04550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAQ69_RS04555	COG2234	aminopeptidase activity
IAQ69_RS04565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAQ69_RS04590	COG0006	proline dipeptidase activity
IAQ69_RS04595	COG2155	Conserved Protein
IAQ69_RS04600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAQ69_RS04615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAQ69_RS04620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAQ69_RS04635	COG3107	peptidoglycan biosynthetic process
IAQ69_RS04650	COG0657	acetylesterase activity
IAQ69_RS04670	COG0741	lytic transglycosylase activity
IAQ69_RS04670	COG1388	LysM domain
IAQ69_RS04675	COG4166	transmembrane transport
IAQ69_RS04680	COG4174	ABC transporter (Permease)
IAQ69_RS04685	COG4239	(ABC) transporter, permease
IAQ69_RS04725	COG0833	amino acid
IAQ69_RS04735	COG0833	amino acid
IAQ69_RS04750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAQ69_RS04755	COG0418	dihydroorotase activity
IAQ69_RS04760	COG3706	GGDEF domain
IAQ69_RS04775	COG1620	l-lactate permease
IAQ69_RS04780	COG2186	Transcriptional regulator
IAQ69_RS04790	COG0277	FAD linked oxidase domain protein
IAQ69_RS04800	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_RS04800	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ69_RS04810	COG0281	malic enzyme
IAQ69_RS04845	COG1741	Belongs to the pirin family
IAQ69_RS04860	COG3739	integral membrane protein
IAQ69_RS04875	COG3706	GGDEF domain
IAQ69_RS04890	COG0302	gtp cyclohydrolase
IAQ69_RS04910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAQ69_RS04915	COG0512	Glutamine amidotransferase of anthranilate synthase
IAQ69_RS04920	COG0174	glutamine synthetase
IAQ69_RS04930	COG3161	chorismate lyase activity
IAQ69_RS04935	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IAQ69_RS04975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAQ69_RS04980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAQ69_RS04985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAQ69_RS04995	COG0596	Alpha beta hydrolase
IAQ69_RS05000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ69_RS05005	COG1335	isochorismatase
IAQ69_RS05010	COG0251	oxidation-reduction process
IAQ69_RS05015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ69_RS05020	COG2233	PERMEase
IAQ69_RS05025	COG2084	Dehydrogenase
IAQ69_RS05035	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS05045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAQ69_RS05050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAQ69_RS05060	COG2175	clavaminate synthase activity
IAQ69_RS05085	COG0556	nucleotide-excision repair
IAQ69_RS05090	COG3040	lipid binding
IAQ69_RS05105	COG1733	regulation of RNA biosynthetic process
IAQ69_RS05145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAQ69_RS05150	COG0076	glutamate decarboxylase activity
IAQ69_RS05160	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_RS05165	COG1522	sequence-specific DNA binding
IAQ69_RS05170	COG3961	Belongs to the TPP enzyme family
IAQ69_RS05175	COG1113	amino acid transport
IAQ69_RS05180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAQ69_RS05185	COG0573	inorganic phosphate transmembrane transporter activity
IAQ69_RS05195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAQ69_RS05205	COG0616	signal peptide processing
IAQ69_RS05245	COG2755	lipolytic protein G-D-S-L family
IAQ69_RS05245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAQ69_RS05250	COG0488	(ABC) transporter
IAQ69_RS05260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAQ69_RS05265	COG1686	Belongs to the peptidase S11 family
IAQ69_RS05290	COG0583	DNA-binding transcription factor activity
IAQ69_RS05295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAQ69_RS05300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IAQ69_RS05305	COG1067	ATP-dependent peptidase activity
IAQ69_RS05345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAQ69_RS05350	COG1966	Carbon starvation protein
IAQ69_RS05355	COG2879	small protein
IAQ69_RS05375	COG0714	Associated with various cellular activities
IAQ69_RS05395	COG0582	viral genome integration into host DNA
IAQ69_RS05400	COG0582	viral genome integration into host DNA
IAQ69_RS05425	COG3620	sequence-specific DNA binding
IAQ69_RS05440	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IAQ69_RS05445	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IAQ69_RS05500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAQ69_RS05510	COG1401	restriction endodeoxyribonuclease activity
IAQ69_RS05580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAQ69_RS05585	COG1765	OsmC-like protein
IAQ69_RS05595	COG0667	Aldo Keto reductase
IAQ69_RS05620	COG0540	Belongs to the ATCase OTCase family
IAQ69_RS05635	COG2031	fatty acid transporter
IAQ69_RS05640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_RS05655	COG4770	biotin carboxylase activity
IAQ69_RS05660	COG1024	Enoyl-CoA hydratase
IAQ69_RS05665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAQ69_RS05670	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS05675	COG1309	transcriptional regulator
IAQ69_RS05680	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_RS05700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IAQ69_RS05705	COG0659	secondary active sulfate transmembrane transporter activity
IAQ69_RS05720	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ69_RS05745	COG2363	Small membrane protein
IAQ69_RS05765	COG0513	Belongs to the DEAD box helicase family
IAQ69_RS05775	COG0778	Nitroreductase
IAQ69_RS05855	COG2199	diguanylate cyclase activity
IAQ69_RS05855	COG2203	Gaf domain
IAQ69_RS05875	COG0515	serine threonine protein kinase
IAQ69_RS05875	COG2815	serine threonine protein kinase
IAQ69_RS05925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ69_RS05940	COG0612	Peptidase, M16
IAQ69_RS05960	COG3025	triphosphatase activity
IAQ69_RS05975	COG0352	thiamine-phosphate diphosphorylase activity
IAQ69_RS06025	COG2267	carboxylic ester hydrolase activity
IAQ69_RS06085	COG2391	methyltransferase activity
IAQ69_RS06105	COG3293	Transposase
IAQ69_RS06110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAQ69_RS06125	COG2353	YceI-like domain
IAQ69_RS06130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAQ69_RS06130	COG0519	Catalyzes the synthesis of GMP from XMP
IAQ69_RS06135	COG0625	glutathione transferase activity
IAQ69_RS06160	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAQ69_RS06160	COG0644	oxidoreductase
IAQ69_RS06165	COG2814	Major facilitator Superfamily
IAQ69_RS06170	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS06175	COG1024	Enoyl-CoA hydratase
IAQ69_RS06180	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_RS06185	COG0183	Belongs to the thiolase family
IAQ69_RS06190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAQ69_RS06215	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IAQ69_RS06215	COG0517	IMP dehydrogenase activity
IAQ69_RS06220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IAQ69_RS06230	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IAQ69_RS06235	COG1137	ATPase activity
IAQ69_RS06270	COG4122	O-methyltransferase activity
IAQ69_RS06280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IAQ69_RS06315	COG2011	ABC-type metal ion transport system permease component
IAQ69_RS06320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAQ69_RS06325	COG1464	Belongs to the NlpA lipoprotein family
IAQ69_RS06345	COG0138	bifunctional purine biosynthesis protein purh
IAQ69_RS06350	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IAQ69_RS06380	COG0445	tRNA wobble uridine modification
IAQ69_RS06400	COG3852	Histidine kinase
IAQ69_RS06420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAQ69_RS06425	COG0575	Belongs to the CDS family
IAQ69_RS06440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAQ69_RS06455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAQ69_RS06460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAQ69_RS06475	COG2137	regulation of response to DNA damage stimulus
IAQ69_RS06485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IAQ69_RS06490	COG1011	Hydrolase
IAQ69_RS06505	COG0268	Binds directly to 16S ribosomal RNA
IAQ69_RS06510	COG0702	epimerase
IAQ69_RS06515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAQ69_RS06525	COG2197	response regulator
IAQ69_RS06530	COG4585	Histidine kinase
IAQ69_RS06535	COG2850	peptidyl-arginine hydroxylation
IAQ69_RS06540	COG0424	maF-like protein
IAQ69_RS06565	COG0697	spore germination
IAQ69_RS06600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAQ69_RS06605	COG3781	membrane
IAQ69_RS06625	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAQ69_RS06625	COG0506	proline dehydrogenase activity
IAQ69_RS06625	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAQ69_RS06640	COG1027	Aspartate ammonia-lyase
IAQ69_RS06650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAQ69_RS06680	COG0316	Belongs to the HesB IscA family
IAQ69_RS06685	COG0822	iron-sulfur transferase activity
IAQ69_RS06695	COG1959	2 iron, 2 sulfur cluster binding
IAQ69_RS06715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAQ69_RS06735	COG1585	Membrane protein implicated in regulation of membrane protease activity
IAQ69_RS06745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAQ69_RS06765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAQ69_RS06770	COG0569	domain protein
IAQ69_RS06775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAQ69_RS06780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAQ69_RS06800	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IAQ69_RS06805	COG0542	response to heat
IAQ69_RS06840	COG0372	Belongs to the citrate synthase family
IAQ69_RS06850	COG1546	Belongs to the CinA family
IAQ69_RS06850	COG1058	Belongs to the CinA family
IAQ69_RS06860	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_RS06880	COG4680	protein conserved in bacteria
IAQ69_RS06885	COG5499	transcription regulator containing HTH domain
IAQ69_RS06895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAQ69_RS06935	COG2814	Major facilitator Superfamily
IAQ69_RS06945	COG3706	GGDEF domain
IAQ69_RS06955	COG0439	Biotin carboxylase
IAQ69_RS06970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAQ69_RS07005	COG0582	viral genome integration into host DNA
IAQ69_RS07055	COG2203	Gaf domain
IAQ69_RS07055	COG2199	diguanylate cyclase activity
IAQ69_RS07170	COG5410	chromosome segregation
IAQ69_RS07230	COG4372	Transposase
IAQ69_RS07355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAQ69_RS07395	COG0596	Alpha beta hydrolase
IAQ69_RS07515	COG0830	nickel cation binding
IAQ69_RS07530	COG0829	nickel cation binding
IAQ69_RS07545	COG0804	urea catabolic process
IAQ69_RS07570	COG4772	TonB-dependent receptor
IAQ69_RS07605	COG1289	transmembrane transporter activity
IAQ69_RS07615	COG0583	DNA-binding transcription factor activity
IAQ69_RS07635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ69_RS07640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAQ69_RS07665	COG2116	formate transmembrane transporter activity
IAQ69_RS07670	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IAQ69_RS07675	COG4773	Receptor
IAQ69_RS07700	COG2132	Multicopper oxidase
IAQ69_RS07725	COG0640	Transcriptional regulator
IAQ69_RS07730	COG1136	(ABC) transporter
IAQ69_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_RS07760	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_RS07770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAQ69_RS07775	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_RS07785	COG2814	Major facilitator Superfamily
IAQ69_RS07790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAQ69_RS07795	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_RS07800	COG2814	Major facilitator Superfamily
IAQ69_RS07815	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS07825	COG1024	Enoyl-CoA hydratase
IAQ69_RS07830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAQ69_RS07835	COG0235	Class ii aldolase
IAQ69_RS07845	COG0183	Belongs to the thiolase family
IAQ69_RS07850	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_RS07860	COG2814	Major facilitator Superfamily
IAQ69_RS07870	COG2814	Major facilitator Superfamily
IAQ69_RS07885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_RS07890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAQ69_RS07895	COG2814	Major facilitator Superfamily
IAQ69_RS07900	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS07905	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS07915	COG1944	ATP diphosphatase activity
IAQ69_RS07935	COG1309	transcriptional regulator
IAQ69_RS07940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAQ69_RS07965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_RS07965	COG1116	anion transmembrane transporter activity
IAQ69_RS07970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAQ69_RS07975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_RS08020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ69_RS08030	COG0864	Transcriptional regulator
IAQ69_RS08035	COG2885	chlorophyll binding
IAQ69_RS08035	COG3047	cAMP biosynthetic process
IAQ69_RS08050	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IAQ69_RS08055	COG3385	transposase activity
IAQ69_RS08060	COG0439	Biotin carboxylase
IAQ69_RS08075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAQ69_RS08095	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_RS08105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ69_RS08115	COG2814	Major facilitator Superfamily
IAQ69_RS08120	COG0583	DNA-binding transcription factor activity
IAQ69_RS08125	COG4948	Mandelate Racemase Muconate Lactonizing
IAQ69_RS08130	COG4829	muconolactone delta-isomerase
IAQ69_RS08140	COG4638	Rieske (2fe-2S)
IAQ69_RS08145	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IAQ69_RS08150	COG0633	Ferredoxin
IAQ69_RS08150	COG0543	2 iron, 2 sulfur cluster binding
IAQ69_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_RS08160	COG3135	benzoate transporter
IAQ69_RS08165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAQ69_RS08170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_RS08175	COG0183	Belongs to the thiolase family
IAQ69_RS08180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAQ69_RS08200	COG0427	acetyl-CoA hydrolase
IAQ69_RS08205	COG0183	Belongs to the thiolase family
IAQ69_RS08210	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS08225	COG0789	Transcriptional regulator
IAQ69_RS08235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAQ69_RS08240	COG0640	Transcriptional regulator
IAQ69_RS08260	COG3122	Protein conserved in bacteria
IAQ69_RS08275	COG0668	transmembrane transport
IAQ69_RS08280	COG1132	(ABC) transporter
IAQ69_RS08290	COG0509	glycine decarboxylation via glycine cleavage system
IAQ69_RS08295	COG2814	Major facilitator Superfamily
IAQ69_RS08310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAQ69_RS08320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IAQ69_RS08325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAQ69_RS08380	COG1525	nuclease
IAQ69_RS08390	COG1294	oxidase, subunit
IAQ69_RS08395	COG1271	oxidase subunit
IAQ69_RS08410	COG1476	TRANSCRIPTIONal
IAQ69_RS08425	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS08430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAQ69_RS08435	COG2207	Transcriptional regulator
IAQ69_RS08440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAQ69_RS08445	COG0730	response to heat
IAQ69_RS08450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAQ69_RS08520	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS08575	COG0552	protein localization to endoplasmic reticulum
IAQ69_RS08580	COG0612	Peptidase, M16
IAQ69_RS08610	COG0516	GMP reductase activity
IAQ69_RS08610	COG0517	IMP dehydrogenase activity
IAQ69_RS08615	COG0133	tryptophan synthase activity
IAQ69_RS08625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ69_RS08645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAQ69_RS08705	COG1294	oxidase, subunit
IAQ69_RS08710	COG4890	Cyd operon protein YbgT
IAQ69_RS08725	COG0772	Belongs to the SEDS family
IAQ69_RS08740	COG0148	phosphopyruvate hydratase activity
IAQ69_RS08760	COG3385	transposase activity
IAQ69_RS08775	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ69_RS08775	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_RS08790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAQ69_RS08795	COG0583	DNA-binding transcription factor activity
IAQ69_RS08825	COG0786	glutamate:sodium symporter activity
IAQ69_RS08865	COG1570	exodeoxyribonuclease VII activity
IAQ69_RS08875	COG3385	transposase activity
IAQ69_RS08885	COG0729	surface antigen
IAQ69_RS08890	COG0477	Major facilitator Superfamily
IAQ69_RS08905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAQ69_RS08915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAQ69_RS08930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAQ69_RS08935	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS08955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_RS08960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_RS08970	COG2890	protein-(glutamine-N5) methyltransferase activity
IAQ69_RS08975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAQ69_RS08995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ69_RS09020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAQ69_RS09025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAQ69_RS09030	COG1845	cytochrome c oxidase, subunit III
IAQ69_RS09035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAQ69_RS09045	COG0360	Binds together with S18 to 16S ribosomal RNA
IAQ69_RS09060	COG0305	Participates in initiation and elongation during chromosome replication
IAQ69_RS09070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAQ69_RS09085	COG1305	Transglutaminase-like
IAQ69_RS09095	COG2308	Evidence 4 Homologs of previously reported genes of
IAQ69_RS09105	COG0069	glutamate synthase activity
IAQ69_RS09130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAQ69_RS09135	COG1454	alcohol dehydrogenase
IAQ69_RS09140	COG0824	Thioesterase
IAQ69_RS09170	COG0183	Belongs to the thiolase family
IAQ69_RS09185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAQ69_RS09195	COG3135	benzoate transporter
IAQ69_RS09215	COG0589	response to stress
IAQ69_RS09220	COG0589	response to stress
IAQ69_RS09235	COG0308	aminopeptidase N
IAQ69_RS09255	COG1253	flavin adenine dinucleotide binding
IAQ69_RS09275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IAQ69_RS09280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IAQ69_RS09295	COG2431	L-lysine efflux transmembrane transporter activity
IAQ69_RS09315	COG0776	regulation of translation
IAQ69_RS09345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAQ69_RS09375	COG1309	transcriptional regulator
IAQ69_RS09380	COG0084	hydrolase, TatD family'
IAQ69_RS09400	COG1663	tetraacyldisaccharide 4'-kinase activity
IAQ69_RS09405	COG1132	(ABC) transporter
IAQ69_RS09415	COG0811	peptide transport
IAQ69_RS09420	COG1475	DNA binding
IAQ69_RS09425	COG1192	Involved in chromosome partitioning
IAQ69_RS09435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IAQ69_RS09440	COG3178	'Phosphotransferase
IAQ69_RS09450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAQ69_RS09455	COG1923	regulation of RNA biosynthetic process
IAQ69_RS09465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAQ69_RS09470	COG0802	atpase or kinase
IAQ69_RS09495	COG2707	UPF0756 membrane protein
IAQ69_RS09500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAQ69_RS09520	COG1643	Atp-dependent helicase
IAQ69_RS09545	COG3634	alkyl hydroperoxide reductase activity
IAQ69_RS09580	COG1254	Belongs to the acylphosphatase family
IAQ69_RS09585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAQ69_RS09585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAQ69_RS09665	COG1464	Belongs to the NlpA lipoprotein family
IAQ69_RS09670	COG1464	Belongs to the NlpA lipoprotein family
IAQ69_RS09675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAQ69_RS09680	COG2011	ABC-type metal ion transport system permease component
IAQ69_RS09685	COG0012	GTP binding
IAQ69_RS09690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAQ69_RS09700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IAQ69_RS09715	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IAQ69_RS09725	COG0386	Belongs to the glutathione peroxidase family
IAQ69_RS09730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAQ69_RS09735	COG0436	Aminotransferase
IAQ69_RS09750	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_RS09775	COG1187	pseudouridine synthase activity
IAQ69_RS09795	COG2351	hydroxyisourate hydrolase activity
IAQ69_RS09800	COG2050	protein possibly involved in aromatic compounds catabolism
IAQ69_RS09810	COG1686	Belongs to the peptidase S11 family
IAQ69_RS09815	COG1252	NADH dehydrogenase
IAQ69_RS09835	COG0501	Belongs to the peptidase M48B family
IAQ69_RS09840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAQ69_RS09865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAQ69_RS09875	COG0527	aspartate kinase activity
IAQ69_RS09890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAQ69_RS09905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAQ69_RS09910	COG2252	PERMEase
IAQ69_RS09940	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAQ69_RS09945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAQ69_RS09955	COG0693	protein deglycase activity
IAQ69_RS09960	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS09970	COG1301	dicarboxylic acid transport
IAQ69_RS09980	COG3139	Protein of unknown function (DUF1315)
IAQ69_RS09985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAQ69_RS09990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAQ69_RS10000	COG0494	nUDIX hydrolase
IAQ69_RS10010	COG0642	Histidine kinase
IAQ69_RS10025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAQ69_RS10040	COG1720	tRNA m6t6A37 methyltransferase activity
IAQ69_RS10050	COG3293	Transposase
IAQ69_RS10055	COG4993	Dehydrogenase
IAQ69_RS10080	COG0826	peptidase U32
IAQ69_RS10085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAQ69_RS10090	COG3634	alkyl hydroperoxide reductase activity
IAQ69_RS10115	COG2862	Uncharacterized protein family, UPF0114
IAQ69_RS10170	COG1131	(ABC) transporter
IAQ69_RS10175	COG0842	Transport permease protein
IAQ69_RS10190	COG2951	lytic endotransglycosylase activity
IAQ69_RS10215	COG0052	Belongs to the universal ribosomal protein uS2 family
IAQ69_RS10225	COG0436	Aminotransferase
IAQ69_RS10230	COG0534	Mate efflux family protein
IAQ69_RS10260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IAQ69_RS10265	COG1381	Involved in DNA repair and RecF pathway recombination
IAQ69_RS10275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAQ69_RS10280	COG0571	ribonuclease III activity
IAQ69_RS10305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAQ69_RS10325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAQ69_RS10335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAQ69_RS10340	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAQ69_RS10350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IAQ69_RS10355	COG4208	sulfate ABC transporter
IAQ69_RS10360	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IAQ69_RS10365	COG0583	DNA-binding transcription factor activity
IAQ69_RS10385	COG0602	queuosine metabolic process
IAQ69_RS10390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAQ69_RS10400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAQ69_RS10405	COG1279	arginine transmembrane transporter activity
IAQ69_RS10410	COG0583	DNA-binding transcription factor activity
IAQ69_RS10415	COG2353	YceI-like domain
IAQ69_RS10420	COG1056	cytidyltransferase-related domain
IAQ69_RS10420	COG1051	belongs to the nudix hydrolase family
IAQ69_RS10425	COG1024	Enoyl-CoA hydratase
IAQ69_RS10435	COG0778	Nitroreductase
IAQ69_RS10445	COG0583	DNA-binding transcription factor activity
IAQ69_RS10450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAQ69_RS10450	COG0047	phosphoribosylformylglycinamidine synthase activity
IAQ69_RS10470	COG2255	four-way junction helicase activity
IAQ69_RS10475	COG1473	amidohydrolase
IAQ69_RS10480	COG0824	Thioesterase
IAQ69_RS10500	COG0823	Involved in the tonB-independent uptake of proteins
IAQ69_RS10520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAQ69_RS10550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAQ69_RS10555	COG0628	permease
IAQ69_RS10560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IAQ69_RS10565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAQ69_RS10570	COG2267	carboxylic ester hydrolase activity
IAQ69_RS10585	COG0658	competence protein
IAQ69_RS10585	COG2333	competence protein COMEC
IAQ69_RS10590	COG1136	(ABC) transporter
IAQ69_RS10610	COG1671	Belongs to the UPF0178 family
IAQ69_RS10630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_RS10670	COG1280	lysine exporter protein (LysE YggA)
IAQ69_RS10675	COG1522	sequence-specific DNA binding
IAQ69_RS10685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IAQ69_RS10690	COG0596	Alpha beta hydrolase
IAQ69_RS10710	COG1113	amino acid transport
IAQ69_RS10715	COG1115	amino acid carrier protein
IAQ69_RS10735	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IAQ69_RS10740	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IAQ69_RS10745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAQ69_RS10750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAQ69_RS10755	COG3300	MHYT domain
IAQ69_RS10755	COG5001	Diguanylate cyclase
IAQ69_RS10775	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IAQ69_RS10785	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS10790	COG0583	DNA-binding transcription factor activity
IAQ69_RS10805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAQ69_RS10810	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IAQ69_RS10820	COG0037	tRNA processing
IAQ69_RS10825	COG0739	heme binding
IAQ69_RS10825	COG1196	nuclear chromosome segregation
IAQ69_RS10825	COG0741	lytic transglycosylase activity
IAQ69_RS10830	COG0501	Belongs to the peptidase M48B family
IAQ69_RS10840	COG2239	Acts as a magnesium transporter
IAQ69_RS10850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAQ69_RS10910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAQ69_RS10920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ69_RS10925	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IAQ69_RS10950	COG0505	Belongs to the CarA family
IAQ69_RS10965	COG1309	transcriptional regulator
IAQ69_RS10970	COG0251	oxidation-reduction process
IAQ69_RS10995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAQ69_RS11020	COG0564	pseudouridine synthase activity
IAQ69_RS11030	COG0358	DNA primase activity
IAQ69_RS11035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IAQ69_RS11045	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IAQ69_RS11075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAQ69_RS11105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAQ69_RS11130	COG0586	Pfam SNARE associated Golgi protein
IAQ69_RS11150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAQ69_RS11160	COG0321	lipoyl(octanoyl) transferase activity
IAQ69_RS11175	COG0531	amino acid
IAQ69_RS11190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IAQ69_RS11195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAQ69_RS11195	COG1648	precorrin-2 dehydrogenase activity
IAQ69_RS11200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAQ69_RS11210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IAQ69_RS11220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IAQ69_RS11235	COG0671	phosphoesterase, PA-phosphatase related
IAQ69_RS11240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_RS11250	COG1538	Outer membrane efflux protein
IAQ69_RS11260	COG0393	Putative heavy-metal-binding
IAQ69_RS11265	COG0393	Putative heavy-metal-binding
IAQ69_RS11270	COG0242	peptide deformylase activity
IAQ69_RS11275	COG0477	Major facilitator Superfamily
IAQ69_RS11305	COG2203	Gaf domain
IAQ69_RS11305	COG2199	diguanylate cyclase activity
IAQ69_RS11325	COG0523	cobalamin synthesis protein
IAQ69_RS11340	COG0625	glutathione transferase activity
IAQ69_RS11345	COG0583	DNA-binding transcription factor activity
IAQ69_RS11350	COG2814	Major facilitator Superfamily
IAQ69_RS11360	COG1607	acyl-coa hydrolase
IAQ69_RS11370	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAQ69_RS11375	COG2059	Chromate
IAQ69_RS11380	COG1115	amino acid carrier protein
IAQ69_RS11385	COG0786	glutamate:sodium symporter activity
IAQ69_RS11395	COG2814	Major facilitator Superfamily
IAQ69_RS11400	COG1289	transmembrane transporter activity
IAQ69_RS11410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAQ69_RS11470	COG2832	Protein of unknown function (DUF454)
IAQ69_RS11500	COG0840	transmembrane signaling receptor activity
IAQ69_RS11570	COG2358	TRAP transporter, solute receptor (TAXI family
IAQ69_RS11585	COG0489	protein tyrosine kinase activity
IAQ69_RS11595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAQ69_RS11595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAQ69_RS11605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ69_RS11610	COG0004	ammonium transporteR
IAQ69_RS11635	COG2081	HI0933 family
IAQ69_RS11650	COG0668	transmembrane transport
IAQ69_RS11670	COG0583	DNA-binding transcription factor activity
IAQ69_RS11675	COG1278	Cold shock
IAQ69_RS11710	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAQ69_RS11715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAQ69_RS11720	COG0713	ATP synthesis coupled electron transport
IAQ69_RS11725	COG0839	Belongs to the complex I subunit 6 family
IAQ69_RS11730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAQ69_RS11745	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IAQ69_RS11765	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAQ69_RS11775	COG2205	protein histidine kinase activity
IAQ69_RS11780	COG0745	RESPONSE REGULATOR receiver
IAQ69_RS11790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ69_RS11800	COG3152	Membrane
IAQ69_RS11835	COG0352	thiamine-phosphate diphosphorylase activity
IAQ69_RS11835	COG0351	phosphomethylpyrimidine kinase
IAQ69_RS11835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAQ69_RS11855	COG2824	Alkylphosphonate utilization operon protein PhnA
IAQ69_RS11875	COG0564	pseudouridine synthase activity
IAQ69_RS11935	COG2132	Multicopper oxidase
IAQ69_RS11940	COG0354	folic acid binding
IAQ69_RS11955	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_RS11980	COG1217	gtp-binding protein TYPA
IAQ69_RS11985	COG2233	PERMEase
IAQ69_RS11995	COG0833	amino acid
IAQ69_RS12015	COG0183	Belongs to the thiolase family
IAQ69_RS12030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_RS12035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAQ69_RS12040	COG2207	Transcriptional regulator
IAQ69_RS12045	COG0183	Belongs to the thiolase family
IAQ69_RS12050	COG1024	Enoyl-CoA hydratase
IAQ69_RS12050	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_RS12070	COG1272	protein, Hemolysin III
IAQ69_RS12075	COG0477	Major facilitator Superfamily
IAQ69_RS12085	COG1408	metallophosphoesterase
IAQ69_RS12090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAQ69_RS12100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAQ69_RS12135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAQ69_RS12140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAQ69_RS12150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAQ69_RS12155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IAQ69_RS12160	COG0625	glutathione transferase activity
IAQ69_RS12165	COG2969	positive regulation of protein catabolic process
IAQ69_RS12180	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_RS12240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAQ69_RS12245	COG1764	response to oxidative stress
IAQ69_RS12285	COG0037	tRNA processing
IAQ69_RS12295	COG0248	Ppx GppA phosphatase
IAQ69_RS12320	COG0072	phenylalanine-tRNA ligase activity
IAQ69_RS12325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAQ69_RS12350	COG1238	metal cluster binding
IAQ69_RS12360	COG0625	glutathione transferase activity
IAQ69_RS12380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAQ69_RS12400	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_RS12410	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IAQ69_RS12420	COG1704	LemA family
IAQ69_RS12435	COG1862	Preprotein translocase
IAQ69_RS12445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAQ69_RS12455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAQ69_RS12475	COG0784	Response regulator, receiver
IAQ69_RS12475	COG2205	protein histidine kinase activity
IAQ69_RS12475	COG5002	protein histidine kinase activity
IAQ69_RS12480	COG1024	Enoyl-CoA hydratase
IAQ69_RS12485	COG2084	Dehydrogenase
IAQ69_RS12490	COG3622	Belongs to the hyi family
IAQ69_RS12515	COG2814	Major facilitator Superfamily
IAQ69_RS12525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAQ69_RS12535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAQ69_RS12540	COG2003	Belongs to the UPF0758 family
IAQ69_RS12545	COG3781	membrane
IAQ69_RS12565	COG2350	Protein conserved in bacteria
IAQ69_RS12595	COG1607	acyl-coa hydrolase
IAQ69_RS12655	COG1183	phosphatidylcholine synthase activity
IAQ69_RS12660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IAQ69_RS12700	COG0741	lytic transglycosylase activity
IAQ69_RS12700	COG1196	nuclear chromosome segregation
IAQ69_RS12700	COG0739	heme binding
IAQ69_RS12705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAQ69_RS12710	COG1702	phosphate starvation-inducible protein PhoH
IAQ69_RS12775	COG1295	ribonuclease BN
IAQ69_RS12785	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAQ69_RS12825	COG0557	exoribonuclease II activity
IAQ69_RS12835	COG0339	signal peptide processing
IAQ69_RS12840	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IAQ69_RS12850	COG0697	spore germination
IAQ69_RS12875	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IAQ69_RS12880	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS12885	COG2072	flavoprotein involved in K transport
IAQ69_RS12890	COG0203	ribosomal protein L17
IAQ69_RS12895	COG0202	RNA polymerase activity
IAQ69_RS12900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAQ69_RS12910	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAQ69_RS12935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAQ69_RS12945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAQ69_RS12950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAQ69_RS12955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAQ69_RS13000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAQ69_RS13015	COG0088	Forms part of the polypeptide exit tunnel
IAQ69_RS13020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAQ69_RS13035	COG0626	cystathionine gamma-synthase activity
IAQ69_RS13040	COG0433	COG0433 Predicted ATPase
IAQ69_RS13050	COG1959	2 iron, 2 sulfur cluster binding
IAQ69_RS13070	COG1301	dicarboxylic acid transport
IAQ69_RS13075	COG1946	Acyl-CoA thioesterase
IAQ69_RS13080	COG2937	Belongs to the GPAT DAPAT family
IAQ69_RS13090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAQ69_RS13095	COG1040	competence protein
IAQ69_RS13100	COG0494	nUDIX hydrolase
IAQ69_RS13110	COG0598	Magnesium transport protein CorA
IAQ69_RS13120	COG2854	intermembrane phospholipid transfer
IAQ69_RS13125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IAQ69_RS13130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IAQ69_RS13135	COG1127	ABC transporter
IAQ69_RS13140	COG0513	Belongs to the DEAD box helicase family
IAQ69_RS13150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAQ69_RS13160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAQ69_RS13165	COG0408	coproporphyrinogen oxidase activity
IAQ69_RS13180	COG1960	acyl-CoA dehydrogenase activity
IAQ69_RS13185	COG1278	Cold shock
IAQ69_RS13195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAQ69_RS13205	COG0534	Mate efflux family protein
IAQ69_RS13215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAQ69_RS13220	COG0254	rRNA binding
IAQ69_RS13225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAQ69_RS13260	COG0628	permease
IAQ69_RS13270	COG1289	transmembrane transporter activity
IAQ69_RS13275	COG2814	Major facilitator Superfamily
IAQ69_RS13300	COG0277	FAD linked oxidase domain protein
IAQ69_RS13305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAQ69_RS13335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAQ69_RS13340	COG5380	lipid catabolic process
IAQ69_RS13345	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IAQ69_RS13355	COG0335	large ribosomal subunit rRNA binding
IAQ69_RS13365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAQ69_RS13370	COG0228	four-way junction DNA binding
IAQ69_RS13415	COG0194	GDP metabolic process
IAQ69_RS13420	COG1758	RNA polymerase activity
IAQ69_RS13425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAQ69_RS13430	COG0675	Transposase, IS605 OrfB family
IAQ69_RS13450	COG3307	-O-antigen
IAQ69_RS13495	COG1704	LemA family
IAQ69_RS13505	COG0493	'glutamate synthase
IAQ69_RS13510	COG0069	glutamate synthase activity
IAQ69_RS13510	COG0070	glutamate synthase
IAQ69_RS13510	COG0067	glutamate synthase
IAQ69_RS13560	COG2226	methyltransferase
IAQ69_RS13565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAQ69_RS13570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAQ69_RS13575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAQ69_RS13595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAQ69_RS13605	COG0675	Transposase, IS605 OrfB family
IAQ69_RS13645	COG0488	(ABC) transporter
IAQ69_RS13655	COG4221	oxidoreductase activity
IAQ69_RS13660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAQ69_RS13675	COG2111	Na H antiporter
IAQ69_RS13675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAQ69_RS13680	COG1006	Multisubunit Na H antiporter MnhC subunit
IAQ69_RS13685	COG0651	ATP synthesis coupled electron transport
IAQ69_RS13690	COG1863	multisubunit Na H antiporter MnhE subunit
IAQ69_RS13695	COG2212	antiporter activity
IAQ69_RS13700	COG1320	monovalent cation:proton antiporter activity
IAQ69_RS13705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAQ69_RS13715	COG0195	Participates in both transcription termination and antitermination
IAQ69_RS13720	COG0779	Required for maturation of 30S ribosomal subunits
IAQ69_RS13755	COG0149	triose-phosphate isomerase activity
IAQ69_RS13775	COG0237	dephospho-CoA kinase activity
IAQ69_RS13785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAQ69_RS13790	COG3123	guanosine phosphorylase activity
IAQ69_RS13795	COG0497	DNA recombination
IAQ69_RS13800	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_RS13820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAQ69_RS13830	COG1132	(ABC) transporter
IAQ69_RS13840	COG1538	Outer membrane efflux protein
IAQ69_RS13855	COG0494	nUDIX hydrolase
IAQ69_RS13860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAQ69_RS13865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAQ69_RS13870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAQ69_RS13880	COG0772	Belongs to the SEDS family
IAQ69_RS13905	COG4974	Belongs to the 'phage' integrase family
IAQ69_RS13910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAQ69_RS13920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAQ69_RS13930	COG1686	Belongs to the peptidase S11 family
IAQ69_RS13935	COG2197	response regulator
IAQ69_RS13940	COG2205	protein histidine kinase activity
IAQ69_RS13950	COG0793	Belongs to the peptidase S41A family
IAQ69_RS13950	COG3409	Peptidoglycan-binding domain 1 protein
IAQ69_RS13955	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAQ69_RS13960	COG0795	lipopolysaccharide-transporting ATPase activity
IAQ69_RS13965	COG0795	lipopolysaccharide-transporting ATPase activity
IAQ69_RS13985	COG0586	Pfam SNARE associated Golgi protein
IAQ69_RS14000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAQ69_RS14000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAQ69_RS14010	COG0004	ammonium transporteR
IAQ69_RS14015	COG0347	Belongs to the P(II) protein family
IAQ69_RS14025	COG0606	chelatase, subunit chli
IAQ69_RS14040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IAQ69_RS14055	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_RS14065	COG0477	Major facilitator Superfamily
IAQ69_RS14070	COG2860	membrane
IAQ69_RS14080	COG1253	flavin adenine dinucleotide binding
IAQ69_RS14095	COG0477	Major facilitator Superfamily
IAQ69_RS14105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAQ69_RS14110	COG0477	Major facilitator Superfamily
IAQ69_RS14130	COG2814	Major facilitator Superfamily
IAQ69_RS14180	COG0758	DNA mediated transformation
IAQ69_RS14190	COG0697	spore germination
IAQ69_RS14195	COG0386	Belongs to the glutathione peroxidase family
IAQ69_RS14210	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_RS14220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAQ69_RS14270	COG1121	(ABC) transporter
IAQ69_RS14275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAQ69_RS14280	COG1683	Conserved Protein
IAQ69_RS14285	COG1280	lysine exporter protein (LysE YggA)
IAQ69_RS14290	COG2837	iron assimilation
IAQ69_RS14305	COG0436	Aminotransferase
IAQ69_RS14310	COG0534	Mate efflux family protein
IAQ69_RS14335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_RS14345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_RS14415	COG3706	GGDEF domain
IAQ69_RS14425	COG1715	Restriction endonuclease
IAQ69_RS14430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAQ69_RS14430	COG0519	Catalyzes the synthesis of GMP from XMP
IAQ69_RS14435	COG0586	Pfam SNARE associated Golgi protein
IAQ69_RS14450	COG1192	Involved in chromosome partitioning
IAQ69_RS14485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAQ69_RS14500	COG4716	Myosin-crossreactive antigen
IAQ69_RS14520	COG0494	nUDIX hydrolase
IAQ69_RS14530	COG3293	Transposase
IAQ69_RS14550	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IAQ69_RS14560	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IAQ69_RS14565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAQ69_RS14575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAQ69_RS14605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAQ69_RS14615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAQ69_RS14630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAQ69_RS14640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAQ69_RS14650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAQ69_RS14655	COG0438	transferase activity, transferring glycosyl groups
IAQ69_RS14665	COG0367	asparagine synthase
IAQ69_RS14680	COG0438	transferase activity, transferring glycosyl groups
IAQ69_RS14685	COG0438	transferase activity, transferring glycosyl groups
IAQ69_RS14725	COG1091	dTDP-4-dehydrorhamnose reductase activity
IAQ69_RS14740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IAQ69_RS14755	COG1596	polysaccharide export
IAQ69_RS14830	COG1194	a g-specific adenine glycosylase
IAQ69_RS14835	COG0739	heme binding
IAQ69_RS14845	COG2818	Glycosylase
IAQ69_RS14850	COG1064	alcohol dehydrogenase
IAQ69_RS14855	COG0583	DNA-binding transcription factor activity
IAQ69_RS14860	COG0656	L-ascorbic acid biosynthetic process
IAQ69_RS14875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IAQ69_RS14905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_RS14920	COG2233	PERMEase
IAQ69_RS14945	COG0129	dihydroxy-acid dehydratase activity
IAQ69_RS14950	COG0129	dihydroxy-acid dehydratase activity
IAQ69_RS14965	COG0428	transporter
IAQ69_RS14975	COG0733	neurotransmitter:sodium symporter activity
IAQ69_RS14980	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_RS14990	COG0693	protein deglycase activity
IAQ69_RS15005	COG2814	Major facilitator Superfamily
IAQ69_RS15010	COG2814	Major facilitator Superfamily
IAQ69_RS15045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAQ69_RS15050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IAQ69_RS15055	COG2951	lytic endotransglycosylase activity
IAQ69_RS15060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAQ69_RS15075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAQ69_RS15100	COG2814	Major facilitator Superfamily
IAQ69_RS15105	COG0861	Integral membrane protein TerC family
IAQ69_RS15110	COG0402	S-adenosylhomocysteine deaminase activity
IAQ69_RS15125	COG0675	Transposase, IS605 OrfB family
IAQ69_RS15140	COG0675	Transposase, IS605 OrfB family
IAQ69_RS15155	COG2814	Major facilitator Superfamily
IAQ69_RS15160	COG3385	transposase activity
IAQ69_RS15170	COG0706	membrane insertase activity
IAQ69_RS15175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IAQ69_RS15180	COG0594	ribonuclease P activity
IAQ69_RS15215	COG1192	Involved in chromosome partitioning
IAQ69_RS15250	COG1346	cytolysis
IAQ69_RS15255	COG1380	Effector of murein hydrolase LrgA
IAQ69_RS15260	COG0583	DNA-binding transcription factor activity
IAQ69_RS15265	COG1309	transcriptional regulator
IAQ69_RS15270	COG0604	alcohol dehydrogenase
IAQ69_RS15305	COG1373	ATPase (AAA superfamily
IAQ69_RS15360	COG2072	flavoprotein involved in K transport
IAQ69_RS15365	COG0492	ferredoxin-NADP+ reductase activity
IAQ69_RS15370	COG0431	NADPH-dependent FMN reductase
IAQ69_RS15375	COG0798	PFAM Bile acid sodium symporter
IAQ69_RS15385	COG0640	Transcriptional regulator
IAQ69_RS15395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IAQ69_RS15405	COG4716	Myosin-crossreactive antigen
IAQ69_RS15420	COG4993	Dehydrogenase
IAQ69_RS15505	COG2963	transposase activity
IAQ69_RS15630	COG4221	oxidoreductase activity
IAQ69_RS15670	COG1660	Displays ATPase and GTPase activities
IAQ69_RS15705	COG4372	Transposase
IAQ69_RS15715	COG2963	transposase activity
IAQ69_RS15735	COG0488	(ABC) transporter
IAQ69_RS15740	COG3173	Aminoglycoside phosphotransferase
IAQ69_RS15755	COG0583	DNA-binding transcription factor activity
IAQ69_RS15815	COG3657	addiction module killer protein
IAQ69_RS15820	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAQ69_RS15855	COG3077	Addiction module antitoxin, RelB DinJ family
IAQ69_RS15875	COG4372	Transposase
IAQ69_RS15900	COG0640	Transcriptional regulator
IAQ69_RS15905	COG0798	PFAM Bile acid sodium symporter
IAQ69_RS15910	COG0431	NADPH-dependent FMN reductase
IAQ69_RS15930	COG3188	usher protein
IAQ69_RS15955	COG2267	carboxylic ester hydrolase activity
IAQ69_RS15955	COG2226	methyltransferase
IAQ69_RS15960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAQ69_RS15960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAQ69_RS15970	COG4106	trans-aconitate 2-methyltransferase activity
IAQ69_RS16045	COG1063	alcohol dehydrogenase
IAQ69_RS16055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAQ69_RS16060	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAQ69_RS16065	COG0022	dehydrogenase e1 component
IAQ69_RS16070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAQ69_RS16075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAQ69_RS16135	COG1454	alcohol dehydrogenase
IAQ69_RS16140	COG0675	Transposase, IS605 OrfB family
IAQ69_RS16155	COG4372	Transposase
IAQ69_RS16165	COG2963	transposase activity
IAQ69_RS16185	COG0582	viral genome integration into host DNA
IAQ69_RS16200	COG2369	cell adhesion
IAQ69_RS16225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAQ69_RS16295	COG2801	Transposase and inactivated derivatives
IAQ69_RS16360	COG0583	DNA-binding transcription factor activity
IAQ69_RS16415	COG3173	Aminoglycoside phosphotransferase
IAQ69_RS16570	COG1660	Displays ATPase and GTPase activities
IAQ69_RS16615	COG0659	secondary active sulfate transmembrane transporter activity
IAQ69_RS16715	COG2433	Pfam Transposase IS66
IAQ69_RS16775	COG2963	transposase activity