UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.47.10 1830 1993 9.6E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.47.10 297 459 8.5E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00698 Acyl transferase domain 2101 2411 1.6E-82 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00698 Acyl transferase domain 571 890 9.2E-84 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:1.10.1200.10 1468 1540 3.5E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:1.10.1200.10 3211 3286 1.1E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF08990 Erythronolide synthase docking 2 25 6.3E-10 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 536 1.1E-13 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1943 2069 1.1E-14 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.366.10 2093 2217 7.2E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.366.10 2283 2396 7.2E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM01294 3215 3282 4.1E-6 T 09-03-2017 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM01294 1472 1538 3.3E-6 T 09-03-2017 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.50.720 2939 3127 8.1E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 2733 2913 2.56E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF55048 697 760 1.26E-6 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1567 1817 2.0E-87 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.1E-90 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00550 Phosphopantetheine attachment site 1475 1538 1.4E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00550 Phosphopantetheine attachment site 3217 3282 3.0E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00825 Beta-ketoacyl synthase 1569 1993 2.9E-209 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00825 Beta-ketoacyl synthase 36 459 9.8E-218 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.50.720 1196 1404 6.7E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF52151 569 698 1.12E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF52151 763 862 1.12E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2939 3113 9.1E-48 T 09-03-2017 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1196 1371 2.2E-45 T 09-03-2017 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF55048 2221 2283 1.96E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2101 2392 7.2E-110 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 871 5.2E-108 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF08659 KR domain 2939 3111 1.4E-53 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF08659 KR domain 1196 1369 1.3E-51 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 1194 1424 1.53E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF14765 Polyketide synthase dehydratase 2457 2724 1.7E-55 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00826 2457 2617 8.1E-81 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3241 3256 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.30.70.250 2222 2282 4.0E-7 T 09-03-2017 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 2936 3180 1.07E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1730 1746 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF52151 2098 2223 3.4E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF52151 2284 2381 3.4E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF53901 1565 1937 1.96E-98 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF47336 3206 3291 2.22E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1497 1512 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.366.10 565 693 1.3E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.366.10 762 884 1.3E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.47.10 1569 1829 1.4E-88 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.47.10 36 296 1.6E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00823 Phosphopantetheine attachment site 1470 1542 4.7E-29 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00823 Phosphopantetheine attachment site 3214 3286 5.7E-32 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1825 1940 5.7E-43 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 5.2E-45 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF47336 1464 1582 2.49E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 976 1185 2.62E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17355 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF53901 31 404 6.74E-106 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 09-03-2017 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 Gene3D G3DSA:3.40.50.2300 63 188 9.3E-30 T 09-03-2017 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 SUPERFAMILY SSF47413 9 69 1.22E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 Pfam PF13377 Periplasmic binding protein-like domain 184 341 3.8E-31 T 09-03-2017 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 SMART SM00354 9 80 8.9E-25 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 57 2.0E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 Gene3D G3DSA:1.10.260.40 10 62 5.8E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 SUPERFAMILY SSF53822 70 342 1.32E-63 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS23650 99bb19a1f73898c52b947d62ec85bc76 352 Gene3D G3DSA:3.40.50.2300 189 320 8.4E-50 T 09-03-2017 UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.266 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 Gene3D G3DSA:1.10.8.60 316 418 4.9E-38 T 09-03-2017 UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 3.6E-16 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 1.5E-49 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 1.3E-194 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 SMART SM00382 113 266 4.1E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 SUPERFAMILY SSF52540 59 405 6.35E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 09-03-2017 UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 Gene3D G3DSA:3.40.50.300 294 311 2.0E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 Gene3D G3DSA:3.40.50.300 63 255 2.0E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 SMART SM01086 317 411 4.5E-32 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS08180 396bede087feb5c2bf38018ba9188cff 426 SMART SM00994 10 49 1.1E-23 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_RS14095 02d85d4ba5592e58980218e3fd774824 308 Pfam PF02016 LD-carboxypeptidase 16 293 1.9E-65 T 09-03-2017 IPR003507 Peptidase family S66 UA74_RS14095 02d85d4ba5592e58980218e3fd774824 308 Gene3D G3DSA:3.40.50.10740 5 167 3.5E-43 T 09-03-2017 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain UA74_RS14095 02d85d4ba5592e58980218e3fd774824 308 PIRSF PIRSF028757 5 307 1.4E-62 T 09-03-2017 IPR003507 Peptidase family S66 UA74_RS14095 02d85d4ba5592e58980218e3fd774824 308 SUPERFAMILY SSF141986 171 299 2.48E-35 T 09-03-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain UA74_RS14095 02d85d4ba5592e58980218e3fd774824 308 SUPERFAMILY SSF52317 4 168 8.7E-40 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS14095 02d85d4ba5592e58980218e3fd774824 308 Gene3D G3DSA:3.50.30.60 175 301 5.9E-34 T 09-03-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 1 178 4.2E-63 T 09-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 SUPERFAMILY SSF52540 1 179 4.03E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 Hamap MF_00328 Guanylate kinase [gmk]. 1 182 33.91 T 09-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 ProSitePatterns PS00856 Guanylate kinase-like signature. 33 50 - T 09-03-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 SMART SM00072 1 182 1.8E-56 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 Gene3D G3DSA:3.40.50.300 83 180 5.0E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 Pfam PF00625 Guanylate kinase 2 178 1.3E-39 T 09-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 Gene3D G3DSA:3.40.50.300 1 41 4.7E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12315 5f3759128a9d229b2880d3e97aa004cf 203 Gene3D G3DSA:3.30.63.10 42 82 4.6E-23 T 09-03-2017 UA74_RS18105 fecd4592a3da375888ff5602755560da 715 Gene3D G3DSA:1.20.1640.10 505 705 1.7E-27 T 09-03-2017 UA74_RS18105 fecd4592a3da375888ff5602755560da 715 Gene3D G3DSA:1.20.1640.10 140 340 5.1E-30 T 09-03-2017 UA74_RS18105 fecd4592a3da375888ff5602755560da 715 Pfam PF03176 MMPL family 45 362 5.9E-45 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 UA74_RS18105 fecd4592a3da375888ff5602755560da 715 Pfam PF03176 MMPL family 498 701 8.7E-25 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 UA74_RS18105 fecd4592a3da375888ff5602755560da 715 SUPERFAMILY SSF82866 141 337 3.14E-31 T 09-03-2017 UA74_RS18105 fecd4592a3da375888ff5602755560da 715 SUPERFAMILY SSF82866 462 700 5.75E-23 T 09-03-2017 UA74_RS19355 7ac09ab47c7fef6285df215f07d48948 182 Gene3D G3DSA:1.10.357.10 6 179 7.1E-21 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS19355 7ac09ab47c7fef6285df215f07d48948 182 SUPERFAMILY SSF46689 5 74 2.98E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS19355 7ac09ab47c7fef6285df215f07d48948 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 8.2E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 SUPERFAMILY SSF55205 12 421 1.13E-104 T 09-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 09-03-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 ProSitePatterns PS00104 EPSP synthase signature 1. 92 106 - T 09-03-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 Gene3D G3DSA:3.65.10.10 210 422 4.5E-56 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 Gene3D G3DSA:3.65.10.10 22 209 2.8E-57 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 425 29.129 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 416 9.5E-113 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 PIRSF PIRSF000505 4 427 1.5E-113 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_RS26665 c62d4f3dece081f4aaaebb0133576fad 440 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 422 2.9E-112 T 09-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_RS21510 c2e46b54c31896ae0be76c9fc9112bfe 299 SUPERFAMILY SSF46785 124 198 8.43E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21510 c2e46b54c31896ae0be76c9fc9112bfe 299 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 125 286 1.3E-29 T 09-03-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UA74_RS21510 c2e46b54c31896ae0be76c9fc9112bfe 299 SUPERFAMILY SSF46785 203 276 7.48E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21510 c2e46b54c31896ae0be76c9fc9112bfe 299 Gene3D G3DSA:1.10.10.10 123 199 1.2E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21510 c2e46b54c31896ae0be76c9fc9112bfe 299 Gene3D G3DSA:1.10.10.10 203 276 3.5E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21510 c2e46b54c31896ae0be76c9fc9112bfe 299 Pfam PF04079 Segregation and condensation complex subunit ScpB 127 285 4.2E-48 T 09-03-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 4711 4904 8.87E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 656 791 1.4E-72 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 4268 4377 5.2E-76 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 6005 6118 7.2E-73 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 2568 2688 3.6E-73 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 4068 4202 5.2E-76 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 2374 2502 3.6E-73 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 857 967 1.4E-72 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.366.10 5810 5935 7.2E-73 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF55048 796 857 4.05E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 120 370 9.4E-90 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5292 5542 2.9E-92 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1849 2099 4.6E-90 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3546 3796 9.9E-92 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 283 299 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1478 1658 3.5E-58 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6644 6824 3.8E-61 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3175 3352 6.1E-53 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4917 5097 3.0E-54 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 6644 6899 2.74E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5455 5471 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6952 6967 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 858 956 1.73E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 657 797 1.73E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF47336 5192 5307 3.93E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:1.10.1200.10 3453 3527 1.5E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:1.10.1200.10 1754 1827 1.3E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:1.10.1200.10 28 103 8.9E-24 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:1.10.1200.10 5194 5269 9.1E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:1.10.1200.10 6923 6999 1.3E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF53901 3543 3918 8.35E-106 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5224 5239 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00825 Beta-ketoacyl synthase 1851 2277 1.1E-225 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00825 Beta-ketoacyl synthase 5294 5720 9.1E-222 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00825 Beta-ketoacyl synthase 122 548 5.9E-225 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00825 Beta-ketoacyl synthase 3548 3974 5.6E-227 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 2569 2658 5.49E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 2376 2508 5.49E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5550 5667 4.4E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2107 2224 2.0E-45 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3804 3921 1.1E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 378 495 2.3E-42 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3709 3725 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF08659 KR domain 3175 3350 2.3E-55 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF08659 KR domain 1478 1657 4.1E-57 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF08659 KR domain 6645 6823 3.5E-57 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF08659 KR domain 4917 5095 2.4E-56 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF47336 3449 3561 2.75E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 4916 5168 2.71E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF53901 5290 5664 1.18E-103 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 6006 6103 1.15E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 5816 5941 1.15E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF47336 1752 1864 1.09E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 498 620 5.3E-15 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5670 5784 2.7E-14 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2227 2343 2.8E-16 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3924 4039 3.6E-15 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00012 Phosphopantetheine attachment site. 57 72 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 4073 4208 5.23E-69 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF52151 4269 4366 5.23E-69 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF55048 4207 4268 1.31E-10 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF53901 1846 2220 1.05E-105 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF55048 5940 6005 5.23E-14 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3482 3497 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF53901 117 492 4.88E-101 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 659 962 2.3E-112 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2380 2686 8.7E-107 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5819 6114 2.3E-121 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4076 4373 8.0E-114 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM01294 31 98 8.6E-5 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM01294 1759 1826 1.2E-5 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM01294 5198 5265 4.0E-5 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM01294 6926 6993 0.0011 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM01294 3456 3523 5.1E-6 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00823 Phosphopantetheine attachment site 1758 1830 8.0E-30 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00823 Phosphopantetheine attachment site 30 102 7.4E-32 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00823 Phosphopantetheine attachment site 3455 3527 2.6E-31 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00823 Phosphopantetheine attachment site 5197 5269 4.8E-31 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00823 Phosphopantetheine attachment site 6925 6997 8.4E-28 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 1475 1730 3.8E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF55048 2507 2568 3.53E-9 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 2968 3160 1.1E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.30.70.250 4206 4267 3.5E-6 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.30.70.250 796 856 5.9E-8 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.30.70.250 2507 2567 2.1E-5 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.30.70.250 5940 6004 1.2E-9 T 09-03-2017 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00550 Phosphopantetheine attachment site 5200 5265 9.7E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00550 Phosphopantetheine attachment site 32 98 3.6E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00550 Phosphopantetheine attachment site 1760 1826 4.5E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00550 Phosphopantetheine attachment site 6927 6993 1.4E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00550 Phosphopantetheine attachment site 3458 3523 7.8E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00826 2751 2911 5.7E-75 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00826 6184 6346 3.9E-45 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00826 1027 1188 8.8E-80 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SMART SM00826 4438 4595 2.0E-73 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.50.720 1478 1688 1.8E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.50.720 4917 5121 3.3E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.50.720 3174 3371 3.3E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.50.720 6645 6843 8.8E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00698 Acyl transferase domain 5818 6122 6.1E-92 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00698 Acyl transferase domain 4076 4391 1.0E-53 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00698 Acyl transferase domain 659 980 3.3E-52 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF00698 Acyl transferase domain 2380 2704 2.8E-50 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF47336 27 135 8.51E-26 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF47336 6919 7004 9.55E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 6461 6629 2.05E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 3174 3384 1.57E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF14765 Polyketide synthase dehydratase 1027 1299 1.5E-57 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF14765 Polyketide synthase dehydratase 6184 6450 3.7E-36 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF14765 Polyketide synthase dehydratase 2751 3017 7.6E-58 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Pfam PF14765 Polyketide synthase dehydratase 4438 4706 6.8E-54 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 SUPERFAMILY SSF51735 1308 1467 1.14E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1785 1800 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 383 549 7.5E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 3809 3974 9.8E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 5555 5719 1.9E-63 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 2112 2275 5.5E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 1851 2111 1.0E-89 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 3548 3808 3.2E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 5294 5554 8.9E-92 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16500 e4f6d1591e9ecb5de146d05cfda40afa 7078 Gene3D G3DSA:3.40.47.10 122 382 8.7E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05195 1edae2234e9e7a62d42c449ddc9141cf 588 Gene3D G3DSA:1.20.1560.10 20 325 8.1E-53 T 09-03-2017 UA74_RS05195 1edae2234e9e7a62d42c449ddc9141cf 588 SMART SM00382 369 563 5.2E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS05195 1edae2234e9e7a62d42c449ddc9141cf 588 Pfam PF00664 ABC transporter transmembrane region 38 299 4.6E-31 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS05195 1edae2234e9e7a62d42c449ddc9141cf 588 SUPERFAMILY SSF90123 18 325 1.44E-53 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS05195 1edae2234e9e7a62d42c449ddc9141cf 588 Gene3D G3DSA:3.40.50.300 345 582 7.1E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05195 1edae2234e9e7a62d42c449ddc9141cf 588 SUPERFAMILY SSF52540 340 587 8.33E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05195 1edae2234e9e7a62d42c449ddc9141cf 588 Pfam PF00005 ABC transporter 360 517 1.3E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS23585 086dfd20643002522f79e1235bba6a16 300 SUPERFAMILY SSF53613 21 289 4.21E-38 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS23585 086dfd20643002522f79e1235bba6a16 300 Gene3D G3DSA:3.40.1190.20 23 299 6.9E-44 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS23585 086dfd20643002522f79e1235bba6a16 300 Pfam PF00294 pfkB family carbohydrate kinase 18 282 1.6E-28 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS23585 086dfd20643002522f79e1235bba6a16 300 PIRSF PIRSF000535 5 300 2.1E-37 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_RS02175 f80153115a113be8aac6e19d4cb7c605 399 Gene3D G3DSA:1.10.260.40 18 73 1.2E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02175 f80153115a113be8aac6e19d4cb7c605 399 Pfam PF06114 Domain of unknown function (DUF955) 210 309 5.5E-17 T 09-03-2017 IPR010359 HTH domain, IrrE-type UA74_RS02175 f80153115a113be8aac6e19d4cb7c605 399 SUPERFAMILY SSF47413 16 74 2.55E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 24 339 8.3E-120 T 09-03-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Hamap MF_01588 DNA ligase [ligA]. 23 694 50.028 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Gene3D G3DSA:3.40.50.10190 621 697 1.1E-19 T 09-03-2017 IPR001357 BRCT domain UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 SUPERFAMILY SSF47781 424 611 5.56E-49 T 09-03-2017 IPR010994 RuvA domain 2-like UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 SMART SM00292 620 697 7.4E-8 T 09-03-2017 IPR001357 BRCT domain UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 SUPERFAMILY SSF50249 338 421 3.08E-26 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Gene3D G3DSA:1.10.287.610 21 88 6.5E-27 T 09-03-2017 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Gene3D G3DSA:2.40.50.140 340 411 3.2E-30 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 SMART SM00532 24 470 6.2E-257 T 09-03-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 SUPERFAMILY SSF56091 23 337 1.03E-111 T 09-03-2017 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 622 689 2.6E-9 T 09-03-2017 IPR001357 BRCT domain UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 352 367 - T 09-03-2017 IPR033136 NAD-dependent DNA ligase, conserved site UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 SUPERFAMILY SSF52113 622 691 9.81E-15 T 09-03-2017 IPR001357 BRCT domain UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Gene3D G3DSA:1.10.150.20 457 513 1.5E-12 T 09-03-2017 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Pfam PF12826 Helix-hairpin-helix motif 538 601 3.6E-21 T 09-03-2017 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 342 419 3.1E-31 T 09-03-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 32 689 5.7E-238 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Gene3D G3DSA:1.10.150.20 532 611 2.4E-28 T 09-03-2017 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Gene3D G3DSA:3.30.470.30 138 273 1.7E-47 T 09-03-2017 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 PIRSF PIRSF001604 17 698 3.6E-230 T 09-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 134 163 - T 09-03-2017 IPR018239 NAD-dependent DNA ligase, active site UA74_RS26285 4fcb7fa2166df032d63f31d13c0a5d95 707 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 428 456 7.4E-10 T 09-03-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 195 0.0084 T 09-03-2017 UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 Gene3D G3DSA:3.40.50.720 6 254 9.6E-84 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 SUPERFAMILY SSF51735 7 254 7.38E-82 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 254 2.4E-70 T 09-03-2017 UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.3E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.3E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09345 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.3E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11505 5b0707ddd376ed9058731f8f9bd0348a 490 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 154 166 - T 09-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 UA74_RS11505 5b0707ddd376ed9058731f8f9bd0348a 490 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 11 485 1.1E-138 T 09-03-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 UA74_RS11505 5b0707ddd376ed9058731f8f9bd0348a 490 Gene3D G3DSA:1.20.1250.20 21 209 5.7E-12 T 09-03-2017 UA74_RS11505 5b0707ddd376ed9058731f8f9bd0348a 490 Pfam PF00854 POT family 93 453 2.1E-73 T 09-03-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 UA74_RS11505 5b0707ddd376ed9058731f8f9bd0348a 490 SUPERFAMILY SSF103473 281 480 7.06E-28 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS11505 5b0707ddd376ed9058731f8f9bd0348a 490 SUPERFAMILY SSF103473 6 209 7.06E-28 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19375 8ee8485ed358a03a0afe39d834dce51c 303 SUPERFAMILY SSF69304 41 297 8.37E-21 T 09-03-2017 UA74_RS19375 8ee8485ed358a03a0afe39d834dce51c 303 Pfam PF07676 WD40-like Beta Propeller Repeat 114 135 2.7E-4 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS19375 8ee8485ed358a03a0afe39d834dce51c 303 Pfam PF07676 WD40-like Beta Propeller Repeat 258 273 0.0086 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS19375 8ee8485ed358a03a0afe39d834dce51c 303 Gene3D G3DSA:2.130.10.10 86 299 4.1E-34 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS16470 ec18b3628a897a856c94791c61072a70 396 Pfam PF07730 Histidine kinase 192 258 5.9E-12 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS16470 ec18b3628a897a856c94791c61072a70 396 SUPERFAMILY SSF55874 301 391 1.96E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS16470 ec18b3628a897a856c94791c61072a70 396 Gene3D G3DSA:3.30.565.10 307 392 8.1E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS04580 adbf4aacb495c8de45f17e37b6bbd834 276 Pfam PF08223 PaaX-like protein C-terminal domain 89 246 2.3E-35 T 09-03-2017 IPR013225 PaaX-like, C-terminal UA74_RS04580 adbf4aacb495c8de45f17e37b6bbd834 276 PIRSF PIRSF020623 1 271 7.0E-64 T 09-03-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 UA74_RS04580 adbf4aacb495c8de45f17e37b6bbd834 276 Pfam PF07848 PaaX-like protein 2 70 6.5E-16 T 09-03-2017 IPR012906 PaaX-like, N-terminal UA74_RS02420 f2d279a7510f0c94276511fabf0061ee 295 SUPERFAMILY SSF140453 58 108 6.15E-5 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS02420 f2d279a7510f0c94276511fabf0061ee 295 Gene3D G3DSA:1.10.287.1060 58 106 9.8E-4 T 09-03-2017 UA74_RS22090 2a8ac3ac824db34ddfbd9a1026bceafd 199 Gene3D G3DSA:1.10.10.60 5 55 2.4E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22090 2a8ac3ac824db34ddfbd9a1026bceafd 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 8.1E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22090 2a8ac3ac824db34ddfbd9a1026bceafd 199 SUPERFAMILY SSF46689 3 81 1.16E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22090 2a8ac3ac824db34ddfbd9a1026bceafd 199 Gene3D G3DSA:1.10.357.10 56 182 4.2E-16 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22090 2a8ac3ac824db34ddfbd9a1026bceafd 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22090 2a8ac3ac824db34ddfbd9a1026bceafd 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 7.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22090 2a8ac3ac824db34ddfbd9a1026bceafd 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 SMART SM00823 Phosphopantetheine attachment site 501 570 4.6E-5 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 SMART SM00823 Phosphopantetheine attachment site 625 694 0.0077 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 SUPERFAMILY SSF53474 692 934 6.42E-38 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Pfam PF00668 Condensation domain 26 315 1.2E-61 T 09-03-2017 IPR001242 Condensation domain UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 SUPERFAMILY SSF47336 618 690 1.44E-17 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Gene3D G3DSA:1.10.1200.10 614 692 7.5E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Gene3D G3DSA:1.10.1200.10 491 568 8.1E-25 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Pfam PF13745 HxxPF-repeated domain 337 426 1.0E-13 T 09-03-2017 UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 SUPERFAMILY SSF52777 205 446 5.56E-48 T 09-03-2017 UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 SUPERFAMILY SSF52777 29 198 2.22E-43 T 09-03-2017 UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Pfam PF00550 Phosphopantetheine attachment site 505 566 4.4E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Pfam PF00550 Phosphopantetheine attachment site 628 690 1.8E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Gene3D G3DSA:3.40.50.1820 698 815 2.2E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Gene3D G3DSA:3.40.50.1820 869 936 2.2E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 Pfam PF00975 Thioesterase domain 712 919 8.3E-20 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS05275 462d6344fccc9facdf437e4a3fdbfe13 939 SUPERFAMILY SSF47336 494 567 3.93E-19 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 13 815 0.0 T 09-03-2017 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 SUPERFAMILY SSF101904 507 822 3.66E-99 T 09-03-2017 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:3.30.1360.40 244 341 2.1E-35 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 619 663 2.4E-8 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 562 608 1.4E-9 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 512 559 1.2E-11 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 720 766 4.3E-13 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 666 714 1.4E-9 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 769 809 1.5E-8 T 09-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 SUPERFAMILY SSF56719 35 495 4.97E-169 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 SMART SM00434 15 473 2.1E-272 T 09-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 8 817 23.38 T 09-03-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 480 5.8E-149 T 09-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:3.90.199.10 35 243 2.8E-111 T 09-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:3.90.199.10 342 406 2.8E-111 T 09-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:2.120.10.90 505 814 4.6E-116 T 09-03-2017 UA74_RS22950 605b6e1ea52e43c0788236e2e44209d6 600 Gene3D G3DSA:3.40.50.1110 188 347 2.7E-16 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS22950 605b6e1ea52e43c0788236e2e44209d6 600 Gene3D G3DSA:3.40.50.1110 35 69 2.7E-16 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS22950 605b6e1ea52e43c0788236e2e44209d6 600 SUPERFAMILY SSF52266 177 345 4.37E-19 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS22950 605b6e1ea52e43c0788236e2e44209d6 600 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 179 335 3.4E-13 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS21255 97ee39df702ce77484ae1f8fb86924a1 205 SMART SM00382 26 205 4.3E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS21255 97ee39df702ce77484ae1f8fb86924a1 205 Gene3D G3DSA:3.40.50.300 2 199 1.0E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21255 97ee39df702ce77484ae1f8fb86924a1 205 SUPERFAMILY SSF52540 1 200 2.72E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21255 97ee39df702ce77484ae1f8fb86924a1 205 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS21255 97ee39df702ce77484ae1f8fb86924a1 205 Pfam PF00005 ABC transporter 17 157 5.7E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS12145 806d2a706ef68bd2977b45bd0b53c047 287 Gene3D G3DSA:3.40.50.720 112 277 1.8E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12145 806d2a706ef68bd2977b45bd0b53c047 287 SUPERFAMILY SSF53223 4 106 1.67E-22 T 09-03-2017 UA74_RS12145 806d2a706ef68bd2977b45bd0b53c047 287 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 5 274 2.3E-70 T 09-03-2017 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+4.2.1.10+1.1.1.25+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12145 806d2a706ef68bd2977b45bd0b53c047 287 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 93 1.6E-19 T 09-03-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UA74_RS12145 806d2a706ef68bd2977b45bd0b53c047 287 SUPERFAMILY SSF51735 107 277 1.17E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12145 806d2a706ef68bd2977b45bd0b53c047 287 Gene3D G3DSA:3.40.192.10 3 111 2.1E-31 T 09-03-2017 UA74_RS26965 a07a517ef3892b0b177854ed761a06e7 278 Gene3D G3DSA:3.30.200.20 1 97 7.6E-39 T 09-03-2017 UA74_RS26965 a07a517ef3892b0b177854ed761a06e7 278 Pfam PF01259 SAICAR synthetase 3 248 1.1E-94 T 09-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS26965 a07a517ef3892b0b177854ed761a06e7 278 Gene3D G3DSA:3.30.470.20 98 227 7.2E-51 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS26965 a07a517ef3892b0b177854ed761a06e7 278 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 276 4.9E-67 T 09-03-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 UA74_RS26965 a07a517ef3892b0b177854ed761a06e7 278 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 273 25.417 T 09-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS26965 a07a517ef3892b0b177854ed761a06e7 278 SUPERFAMILY SSF56104 1 276 9.48E-95 T 09-03-2017 UA74_RS09000 8d8d984d023f169cdc373767d72eaef0 326 SUPERFAMILY SSF53067 10 322 1.17E-62 T 09-03-2017 UA74_RS09000 8d8d984d023f169cdc373767d72eaef0 326 ProSitePatterns PS01125 ROK family signature. 146 173 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS09000 8d8d984d023f169cdc373767d72eaef0 326 Gene3D G3DSA:3.30.420.40 150 305 1.5E-55 T 09-03-2017 UA74_RS09000 8d8d984d023f169cdc373767d72eaef0 326 Pfam PF00480 ROK family 13 318 2.0E-66 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS09000 8d8d984d023f169cdc373767d72eaef0 326 Gene3D G3DSA:3.30.420.40 7 149 5.5E-48 T 09-03-2017 UA74_RS30225 6b5cdb7e6b3763987383e78e77541b02 139 Pfam PF13411 MerR HTH family regulatory protein 9 73 7.4E-17 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS30225 6b5cdb7e6b3763987383e78e77541b02 139 SUPERFAMILY SSF46955 8 123 2.89E-24 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS30225 6b5cdb7e6b3763987383e78e77541b02 139 Gene3D G3DSA:1.10.1660.10 9 123 9.0E-27 T 09-03-2017 UA74_RS30225 6b5cdb7e6b3763987383e78e77541b02 139 SMART SM00422 8 78 1.8E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13390 fde5873098b31599474d9656af177b59 362 Pfam PF07728 AAA domain (dynein-related subfamily) 20 149 3.3E-9 T 09-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_RS13390 fde5873098b31599474d9656af177b59 362 Gene3D G3DSA:3.40.50.300 11 151 6.2E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13390 fde5873098b31599474d9656af177b59 362 SUPERFAMILY SSF52540 7 156 9.11E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13390 fde5873098b31599474d9656af177b59 362 SMART SM00382 17 160 1.2E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 Pfam PF00107 Zinc-binding dehydrogenase 190 320 7.7E-29 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 SUPERFAMILY SSF51735 156 326 1.06E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 7.5E-203 T 09-03-2017 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 Gene3D G3DSA:3.40.50.720 183 302 6.5E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 Gene3D G3DSA:3.90.180.10 1 182 3.8E-55 T 09-03-2017 IPR011032 GroES-like UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 SMART SM00829 12 361 9.1E-4 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 SUPERFAMILY SSF50129 3 186 1.83E-55 T 09-03-2017 IPR011032 GroES-like UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 2.0E-28 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS11405 1f5f0967d358712259bfb6d7994f876d 361 SUPERFAMILY SSF50129 310 360 1.18E-7 T 09-03-2017 IPR011032 GroES-like UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 Gene3D G3DSA:1.10.10.10 26 88 8.5E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 SUPERFAMILY SSF46785 23 90 5.0E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 Gene3D G3DSA:3.90.1150.10 351 429 4.9E-6 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 SUPERFAMILY SSF53383 106 466 9.94E-84 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 1.2E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 1.2E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 SMART SM00345 28 87 1.0E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 Gene3D G3DSA:3.40.640.10 144 350 2.2E-50 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 2.1E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS04110 5f9a5bab1a238e205bb3837356125c20 488 Pfam PF00155 Aminotransferase class I and II 135 462 5.6E-22 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 SUPERFAMILY SSF47203 227 381 7.89E-52 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 216 1.4E-19 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 Gene3D G3DSA:1.20.140.10 220 381 4.9E-60 T 09-03-2017 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 6.4E-18 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 Gene3D G3DSA:1.10.540.10 1 121 1.5E-22 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 7.9E-44 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 Gene3D G3DSA:2.40.110.10 124 219 5.3E-30 T 09-03-2017 UA74_RS13635 89201df0ac755b96f25aa8b9be72d8ca 389 SUPERFAMILY SSF56645 1 241 7.07E-62 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 28.097 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.7E-36 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.7E-36 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.7E-36 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 09-03-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 5.0E-16 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 SUPERFAMILY SSF110324 2 81 9.07E-32 T 09-03-2017 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 Gene3D G3DSA:2.40.50.100 20 81 8.5E-30 T 09-03-2017 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 Pfam PF01016 Ribosomal L27 protein 2 80 1.2E-36 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08310 c5810897faef62aac76e36761e3b0b92 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 6.9E-37 T 09-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS20545 67a88083db0d2a391079c14414fd7a59 336 SUPERFAMILY SSF53474 5 262 6.69E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20545 67a88083db0d2a391079c14414fd7a59 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.7E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20545 67a88083db0d2a391079c14414fd7a59 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.7E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20545 67a88083db0d2a391079c14414fd7a59 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.7E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20545 67a88083db0d2a391079c14414fd7a59 336 Pfam PF00561 alpha/beta hydrolase fold 27 140 1.0E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20545 67a88083db0d2a391079c14414fd7a59 336 Gene3D G3DSA:3.40.50.1820 3 262 4.4E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 Pfam PF00486 Transcriptional regulatory protein, C terminal 15 80 6.3E-9 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 Pfam PF03704 Bacterial transcriptional activator domain 103 244 2.0E-30 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 SUPERFAMILY SSF46894 4 95 2.35E-13 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 SMART SM00862 15 96 9.3E-13 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 SMART SM01043 103 244 4.7E-36 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 Gene3D G3DSA:1.10.10.10 9 97 6.3E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 SUPERFAMILY SSF48452 98 252 7.21E-31 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS07785 5cf4945b0da931e2052f290e60ad2fea 286 Gene3D G3DSA:1.25.40.10 115 223 9.0E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS26825 e83e58e621ec9021567ae1c1e8ecc0a6 179 Pfam PF00293 NUDIX domain 47 160 5.6E-11 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS26825 e83e58e621ec9021567ae1c1e8ecc0a6 179 Gene3D G3DSA:3.90.79.10 41 164 8.5E-18 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS26825 e83e58e621ec9021567ae1c1e8ecc0a6 179 SUPERFAMILY SSF55811 29 168 7.72E-20 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS14965 d600a7deb97dd608bbe84f40ad3495ae 204 Gene3D G3DSA:1.10.357.10 8 199 2.0E-34 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS14965 d600a7deb97dd608bbe84f40ad3495ae 204 SUPERFAMILY SSF48498 83 199 1.85E-11 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS14965 d600a7deb97dd608bbe84f40ad3495ae 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 3.2E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS14965 d600a7deb97dd608bbe84f40ad3495ae 204 SUPERFAMILY SSF46689 5 83 1.55E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14965 d600a7deb97dd608bbe84f40ad3495ae 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.7E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS14965 d600a7deb97dd608bbe84f40ad3495ae 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.7E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.9E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.9E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.9E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.9E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 6.5E-65 T 09-03-2017 UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.2E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.2E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.2E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 221 5.6E-7 T 09-03-2017 UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 Gene3D G3DSA:3.40.50.720 5 246 8.7E-85 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05795 226a6903a85f0de1720ea6742d0139a3 249 SUPERFAMILY SSF51735 5 246 6.44E-82 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 SMART SM00487 109 310 6.7E-12 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 Pfam PF00271 Helicase conserved C-terminal domain 445 565 2.8E-11 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 SMART SM00490 481 565 2.6E-5 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 Pfam PF00176 SNF2 family N-terminal domain 125 298 7.6E-9 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 SUPERFAMILY SSF52540 235 278 5.89E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 SUPERFAMILY SSF52540 420 604 5.89E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 Gene3D G3DSA:3.40.50.300 422 568 4.0E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 Gene3D G3DSA:3.40.50.300 121 285 2.4E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19210 191777b55812886859f4a5cebd6520dc 974 SUPERFAMILY SSF52540 71 296 2.66E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 Gene3D G3DSA:4.10.950.10 197 272 2.3E-29 T 09-03-2017 IPR014726 Ribosomal protein L2, domain 3 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 6.2E-54 T 09-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 Gene3D G3DSA:2.30.30.30 120 196 1.3E-30 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 1.9E-124 T 09-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 SMART SM01383 42 119 4.4E-41 T 09-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 1.8E-32 T 09-03-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 Gene3D G3DSA:2.40.50.140 1 115 1.1E-49 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 PIRSF PIRSF002158 3 274 4.3E-93 T 09-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 47.172 T 09-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 SUPERFAMILY SSF50249 3 126 5.48E-49 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 SMART SM01382 125 253 1.1E-86 T 09-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 09-03-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02945 8ad3832c7e2332e3ce67ca1f2362842c 277 SUPERFAMILY SSF50104 127 271 1.56E-54 T 09-03-2017 IPR008991 Translation protein SH3-like domain UA74_RS03175 884359c84f23c2462d7bf9ae01b58d9f 139 SUPERFAMILY SSF55729 6 118 2.13E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS03175 884359c84f23c2462d7bf9ae01b58d9f 139 Pfam PF13673 Acetyltransferase (GNAT) domain 38 94 4.7E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS03175 884359c84f23c2462d7bf9ae01b58d9f 139 Gene3D G3DSA:3.40.630.30 6 119 3.7E-19 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS04505 8292e251cf26ebb91dd2dc78e0e0d7e7 112 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 2.1E-21 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS04505 8292e251cf26ebb91dd2dc78e0e0d7e7 112 Gene3D G3DSA:1.10.10.10 2 104 5.0E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04505 8292e251cf26ebb91dd2dc78e0e0d7e7 112 SUPERFAMILY SSF46785 3 105 3.47E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 Gene3D G3DSA:3.90.180.10 5 183 4.5E-48 T 09-03-2017 IPR011032 GroES-like UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 148 7.3E-25 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 SUPERFAMILY SSF50129 7 187 9.13E-42 T 09-03-2017 IPR011032 GroES-like UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 Gene3D G3DSA:3.40.50.720 184 298 1.3E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 SMART SM00829 17 353 1.1E-4 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 SUPERFAMILY SSF51735 153 314 2.89E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 74 88 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS13440 2c372f384a02810f784e7291540d0c71 361 Pfam PF00107 Zinc-binding dehydrogenase 190 314 1.2E-14 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS09075 6610d4a9000ce2104ffcbc2412429d47 92 Pfam PF10939 Protein of unknown function (DUF2631) 9 72 1.0E-28 T 09-03-2017 IPR024341 Protein of unknown function DUF2631 UA74_RS09075 6610d4a9000ce2104ffcbc2412429d47 92 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 13 87 4.0E-10 T 09-03-2017 IPR024341 Protein of unknown function DUF2631 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 83 6.8E-23 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 SUPERFAMILY SSF50615 9 84 8.37E-24 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 SUPERFAMILY SSF52540 87 358 2.28E-86 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 7 471 54.284 T 09-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 SMART SM00382 152 338 7.5E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 9 469 1.2E-241 T 09-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 Gene3D G3DSA:1.10.1140.10 356 471 4.6E-47 T 09-03-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 140 353 3.8E-62 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 Gene3D G3DSA:2.40.10.170 8 84 2.6E-29 T 09-03-2017 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 SUPERFAMILY SSF47917 356 471 4.45E-48 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07175 60cc8242a982324e57c66ae4329c5773 473 Gene3D G3DSA:3.40.50.300 86 355 3.7E-100 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15745 4ddf5b8b14b85e737e88f56581b03b8c 120 Pfam PF02467 Transcription factor WhiB 52 97 2.7E-11 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 Pfam PF07687 Peptidase dimerisation domain 174 283 1.1E-20 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 SUPERFAMILY SSF53187 3 177 2.0E-54 T 09-03-2017 UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 SUPERFAMILY SSF53187 297 376 2.0E-54 T 09-03-2017 UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 Gene3D G3DSA:3.30.70.360 187 275 1.5E-23 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 SUPERFAMILY SSF55031 178 276 1.5E-18 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 Pfam PF01546 Peptidase family M20/M25/M40 70 376 6.4E-31 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 Gene3D G3DSA:3.40.630.10 320 377 1.2E-64 T 09-03-2017 UA74_RS22825 370a28cc52ce24b26213f06b11fec639 380 Gene3D G3DSA:3.40.630.10 4 186 1.2E-64 T 09-03-2017 UA74_RS23305 33c4e3171dab2031005554cfe2066b58 380 Pfam PF00561 alpha/beta hydrolase fold 61 364 1.6E-29 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS23305 33c4e3171dab2031005554cfe2066b58 380 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 32 376 4.0E-130 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 UA74_RS23305 33c4e3171dab2031005554cfe2066b58 380 Gene3D G3DSA:3.40.50.1820 42 376 1.4E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23305 33c4e3171dab2031005554cfe2066b58 380 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 18 378 44.955 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 UA74_RS23305 33c4e3171dab2031005554cfe2066b58 380 SUPERFAMILY SSF53474 34 377 1.46E-95 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23305 33c4e3171dab2031005554cfe2066b58 380 PIRSF PIRSF000443 25 379 9.5E-123 T 09-03-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 Gene3D G3DSA:3.50.50.60 109 295 2.9E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 304 6.7E-121 T 09-03-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 293 1.0E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 09-03-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 Gene3D G3DSA:3.50.50.60 5 108 5.6E-34 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 2.2E-77 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 SUPERFAMILY SSF51905 6 302 1.44E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.3E-35 T 09-03-2017 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.3E-35 T 09-03-2017 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-35 T 09-03-2017 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.3E-35 T 09-03-2017 UA74_RS30400 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.3E-35 T 09-03-2017 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 Gene3D G3DSA:1.10.260.40 14 72 7.4E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 Pfam PF00931 NB-ARC domain 180 418 2.6E-15 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF48452 686 787 1.01E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00028 681 714 89.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00028 641 674 230.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00028 724 757 7.3 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF48452 585 716 4.05E-11 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 Gene3D G3DSA:3.40.50.300 164 276 2.3E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00530 18 74 2.9E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 Gene3D G3DSA:1.25.40.10 615 796 1.5E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 Pfam PF13424 Tetratricopeptide repeat 683 754 4.2E-8 T 09-03-2017 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF47413 14 72 3.75E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 PRINTS PR00364 Disease resistance protein signature 185 200 3.1E-11 T 09-03-2017 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 PRINTS PR00364 Disease resistance protein signature 347 361 3.1E-11 T 09-03-2017 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 PRINTS PR00364 Disease resistance protein signature 262 276 3.1E-11 T 09-03-2017 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 Pfam PF13560 Helix-turn-helix domain 15 77 6.0E-11 T 09-03-2017 UA74_RS20935 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF52540 147 414 7.46E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05750 987fa0c2e3fa9e761b6899a73d8f3be0 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05750 987fa0c2e3fa9e761b6899a73d8f3be0 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05750 987fa0c2e3fa9e761b6899a73d8f3be0 192 Pfam PF13977 Bacterial transcriptional repressor 77 177 5.2E-7 T 09-03-2017 UA74_RS05750 987fa0c2e3fa9e761b6899a73d8f3be0 192 SUPERFAMILY SSF46689 4 70 1.49E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05750 987fa0c2e3fa9e761b6899a73d8f3be0 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 2.3E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05750 987fa0c2e3fa9e761b6899a73d8f3be0 192 Gene3D G3DSA:1.10.357.10 4 184 1.2E-30 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS05750 987fa0c2e3fa9e761b6899a73d8f3be0 192 SUPERFAMILY SSF48498 76 174 4.08E-6 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF04408 Helicase associated domain (HA2) 467 558 2.9E-18 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00382 95 385 8.6E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF11898 Domain of unknown function (DUF3418) 713 1297 9.9E-232 T 09-03-2017 IPR024590 RNA helicase HrpA, C-terminal UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Gene3D G3DSA:3.40.50.300 79 236 1.3E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00487 76 262 7.4E-25 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00847 465 560 1.6E-37 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00490 305 405 8.0E-13 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 583 698 2.7E-15 T 09-03-2017 IPR011709 Domain of unknown function DUF1605 UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF00271 Helicase conserved C-terminal domain 287 404 2.0E-9 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Gene3D G3DSA:3.40.50.300 268 417 1.1E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SUPERFAMILY SSF52540 77 602 5.11E-112 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12040 cf6a13e30859c5b4bdc73eee3141b4d3 1300 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 15 1296 0.0 T 09-03-2017 IPR010222 RNA helicase HrpA GO:0004004 UA74_RS00065 252c187beddd6e8b05efb6184a73205f 147 Gene3D G3DSA:3.40.1000.10 13 147 2.1E-44 T 09-03-2017 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 UA74_RS00065 252c187beddd6e8b05efb6184a73205f 147 SUPERFAMILY SSF55724 10 147 2.88E-43 T 09-03-2017 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 UA74_RS00065 252c187beddd6e8b05efb6184a73205f 147 Pfam PF09449 Domain of unknown function (DUF2020) 10 147 1.0E-36 T 09-03-2017 IPR018567 Domain of unknown function DUF2020 UA74_RS11800 3cf190d3358a7d89ee11ddd0d818f48a 408 Pfam PF00534 Glycosyl transferases group 1 208 368 1.0E-32 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS11800 3cf190d3358a7d89ee11ddd0d818f48a 408 SUPERFAMILY SSF53756 1 392 1.28E-83 T 09-03-2017 UA74_RS11800 3cf190d3358a7d89ee11ddd0d818f48a 408 Gene3D G3DSA:3.40.50.2000 182 368 3.3E-28 T 09-03-2017 UA74_RS11800 3cf190d3358a7d89ee11ddd0d818f48a 408 Gene3D G3DSA:3.40.50.2000 31 130 4.7E-4 T 09-03-2017 UA74_RS11800 3cf190d3358a7d89ee11ddd0d818f48a 408 Pfam PF13439 Glycosyltransferase Family 4 22 196 3.5E-32 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 430 2.5E-128 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 434 29.183 T 09-03-2017 IPR026593 Protein translocase subunit SecY UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 Gene3D G3DSA:1.10.3370.10 2 435 2.9E-154 T 09-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 312 334 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 367 385 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 2.8E-99 T 09-03-2017 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 SUPERFAMILY SSF103491 2 425 1.31E-122 T 09-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 PIRSF PIRSF004557 1 435 5.1E-123 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 09-03-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 09-03-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS03085 4fc4d19fe499f2ddd89310587cc580a3 435 Pfam PF00344 SecY translocase 75 418 2.9E-114 T 09-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 Pfam PF05239 PRC-barrel domain 93 166 9.5E-10 T 09-03-2017 IPR027275 PRC-barrel domain UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 1 166 22.004 T 09-03-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 1 166 5.2E-39 T 09-03-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 Gene3D G3DSA:2.40.30.60 2 89 5.8E-20 T 09-03-2017 IPR002676 RimM protein GO:0006364 UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 SUPERFAMILY SSF50346 96 166 8.11E-17 T 09-03-2017 IPR011033 PRC-barrel-like UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 Pfam PF01782 RimM N-terminal domain 3 85 1.0E-19 T 09-03-2017 IPR002676 RimM protein GO:0006364 UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 Gene3D G3DSA:2.30.30.240 96 166 1.3E-18 T 09-03-2017 UA74_RS08935 b63fac81bbf774a6c783ec4c5fef6d78 173 SUPERFAMILY SSF50447 2 89 1.77E-16 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 SUPERFAMILY SSF53474 406 646 2.04E-61 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 Gene3D G3DSA:2.120.10.30 159 260 1.4E-38 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 Gene3D G3DSA:2.120.10.30 34 122 1.4E-38 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 Pfam PF07676 WD40-like Beta Propeller Repeat 95 127 2.3E-5 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 Pfam PF07676 WD40-like Beta Propeller Repeat 56 86 0.31 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 Pfam PF07676 WD40-like Beta Propeller Repeat 179 216 5.4E-4 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 SUPERFAMILY SSF82171 331 369 7.85E-27 T 09-03-2017 UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 SUPERFAMILY SSF82171 19 256 7.85E-27 T 09-03-2017 UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 Pfam PF00326 Prolyl oligopeptidase family 441 647 4.4E-45 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS10795 741c8331c9056346cc97842ec5946a9b 656 Gene3D G3DSA:3.40.50.1820 407 646 2.8E-63 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17615 4bcbc44d122c2edee258e51b0f5d3b6c 370 SUPERFAMILY SSF51445 276 304 5.13E-6 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS17615 4bcbc44d122c2edee258e51b0f5d3b6c 370 SUPERFAMILY SSF51445 17 167 5.13E-6 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS17615 4bcbc44d122c2edee258e51b0f5d3b6c 370 SUPERFAMILY SSF51445 199 247 5.13E-6 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 Gene3D G3DSA:1.10.260.40 7 60 1.3E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 Gene3D G3DSA:3.40.50.2300 61 103 2.6E-4 T 09-03-2017 UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 Gene3D G3DSA:3.40.50.2300 161 307 1.0E-33 T 09-03-2017 UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 SUPERFAMILY SSF47413 6 66 1.04E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 SMART SM00354 6 78 1.4E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 54 2.0E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 SUPERFAMILY SSF53822 146 330 3.85E-33 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS18215 535343241b1d77bf0cd0100ae3fa6e4f 334 Pfam PF13377 Periplasmic binding protein-like domain 167 327 8.5E-32 T 09-03-2017 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 Pfam PF00072 Response regulator receiver domain 5 115 5.6E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 Gene3D G3DSA:1.10.10.10 160 218 6.4E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 SUPERFAMILY SSF46894 150 219 8.5E-22 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.5E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.5E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.5E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 SUPERFAMILY SSF52172 3 130 5.55E-32 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 SMART SM00448 3 115 3.8E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 SMART SM00421 156 213 1.1E-25 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 1.6E-20 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS18175 d13d88a7bfbb320c4205dfa16641cdbd 224 Gene3D G3DSA:3.40.50.2300 2 159 1.9E-39 T 09-03-2017 UA74_RS25345 c9b6d1ac11b85a8031614956964b9a01 555 Pfam PF00773 RNB domain 49 354 1.1E-43 T 09-03-2017 UA74_RS25345 c9b6d1ac11b85a8031614956964b9a01 555 SMART SM00955 49 367 4.7E-60 T 09-03-2017 UA74_RS25345 c9b6d1ac11b85a8031614956964b9a01 555 SUPERFAMILY SSF50249 13 409 8.0E-88 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS18625 3a318bf9bcb43374bbd692be4f0ab6d6 172 SUPERFAMILY SSF55729 69 167 5.32E-19 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS18625 3a318bf9bcb43374bbd692be4f0ab6d6 172 Gene3D G3DSA:3.40.630.30 4 169 9.2E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS18625 3a318bf9bcb43374bbd692be4f0ab6d6 172 Pfam PF13673 Acetyltransferase (GNAT) domain 82 166 6.0E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS15620 7890996e0df3d415ebd921d1ed787768 358 Gene3D G3DSA:3.40.710.10 5 313 4.2E-53 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS15620 7890996e0df3d415ebd921d1ed787768 358 SUPERFAMILY SSF56601 2 303 3.5E-54 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS15620 7890996e0df3d415ebd921d1ed787768 358 Pfam PF00144 Beta-lactamase 5 300 1.5E-49 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 SMART SM00448 2 112 1.8E-43 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 SUPERFAMILY SSF52172 1 125 1.38E-40 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 SMART SM00862 148 224 1.1E-29 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 SUPERFAMILY SSF46894 124 225 9.92E-33 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 Gene3D G3DSA:3.40.50.2300 1 123 6.0E-39 T 09-03-2017 UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 5.2E-27 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS02220 264205acbdefd99d4fd569be232c5205 226 Gene3D G3DSA:1.10.10.10 127 225 4.9E-36 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00485 67358f2fa99316d68ff0fddf1f42f4c0 186 Pfam PF00210 Ferritin-like domain 18 152 3.3E-33 T 09-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 UA74_RS00485 67358f2fa99316d68ff0fddf1f42f4c0 186 SUPERFAMILY SSF47240 14 157 3.45E-42 T 09-03-2017 IPR009078 Ferritin-like superfamily UA74_RS00485 67358f2fa99316d68ff0fddf1f42f4c0 186 Gene3D G3DSA:1.20.1260.10 6 166 1.2E-42 T 09-03-2017 IPR012347 Ferritin-related UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 Gene3D G3DSA:1.10.8.60 342 407 2.2E-21 T 09-03-2017 UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 331 1.5E-45 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 Gene3D G3DSA:3.40.50.300 156 341 9.7E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 Pfam PF01434 Peptidase family M41 395 602 4.4E-76 T 09-03-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 SMART SM00382 196 335 5.4E-25 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 SUPERFAMILY SSF140990 414 607 3.01E-67 T 09-03-2017 UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 113 603 6.1E-225 T 09-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 SUPERFAMILY SSF52540 156 403 2.05E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01515 b50e7896f0fd69f847110a1c24f04841 809 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 639 36.011 T 09-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 287 4.4E-68 T 09-03-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Gene3D G3DSA:3.30.470.20 183 314 1.4E-54 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 SMART SM01209 101 287 1.1E-111 T 09-03-2017 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 408 2.4E-25 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Gene3D G3DSA:3.40.50.20 2 93 1.1E-30 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Gene3D G3DSA:3.90.600.10 322 411 2.0E-27 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 5.7E-28 T 09-03-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 09-03-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 38.983 T 09-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 SUPERFAMILY SSF51246 321 410 9.42E-23 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 SMART SM01210 322 411 5.1E-35 T 09-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 SUPERFAMILY SSF56059 102 312 1.28E-50 T 09-03-2017 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 SUPERFAMILY SSF52440 2 101 2.45E-29 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 Gene3D G3DSA:3.30.1490.20 121 182 4.8E-15 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS29535 f91fa1d52b4761b16f24e31f3981ed7b 423 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 410 1.3E-144 T 09-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS21285 ea57312398085e6059984de2bb7b256d 424 SUPERFAMILY SSF51905 6 308 3.7E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS21285 ea57312398085e6059984de2bb7b256d 424 SUPERFAMILY SSF51905 389 419 3.7E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS21285 ea57312398085e6059984de2bb7b256d 424 Gene3D G3DSA:3.50.50.60 3 118 1.2E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS21285 ea57312398085e6059984de2bb7b256d 424 Gene3D G3DSA:3.50.50.60 209 305 1.2E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS21285 ea57312398085e6059984de2bb7b256d 424 Pfam PF01593 Flavin containing amine oxidoreductase 13 281 2.1E-21 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 SMART SM00649 11 142 3.4E-38 T 09-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 13 67 2.0E-9 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 Gene3D G3DSA:3.30.1550.10 12 71 1.8E-12 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 43 74 0.001 T 09-03-2017 UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 SUPERFAMILY SSF54747 13 85 5.23E-11 T 09-03-2017 IPR020784 Ribosomal protein L11, N-terminal UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 Gene3D G3DSA:1.10.10.250 72 142 3.8E-26 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 SUPERFAMILY SSF46906 69 141 1.57E-20 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 141 2.9E-23 T 09-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_RS11240 1c586ab8634ec2a7f4a3cb71ad77496e 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 143 21.562 T 09-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 UA74_RS27625 e9c105524eb24df7262909dc2ce83795 203 SMART SM00860 28 164 6.8E-5 T 09-03-2017 IPR018958 SMI1/KNR4-like domain UA74_RS27625 e9c105524eb24df7262909dc2ce83795 203 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 28 145 2.1E-9 T 09-03-2017 IPR018958 SMI1/KNR4-like domain UA74_RS27625 e9c105524eb24df7262909dc2ce83795 203 SUPERFAMILY SSF160631 22 165 1.44E-10 T 09-03-2017 UA74_RS23710 a36cfa1e0e88ddc0e43b94e68856ba20 275 SUPERFAMILY SSF52266 34 254 2.83E-63 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS23710 a36cfa1e0e88ddc0e43b94e68856ba20 275 Gene3D G3DSA:3.40.50.1110 31 255 9.9E-70 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS23710 a36cfa1e0e88ddc0e43b94e68856ba20 275 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 39 254 2.6E-23 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 PIRSF PIRSF001423 2 553 1.9E-273 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 SUPERFAMILY SSF111326 5 549 1.44E-245 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 1.3E-273 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 Gene3D G3DSA:3.40.50.10730 138 344 4.0E-82 T 09-03-2017 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 Hamap MF_00577 Urocanate hydratase [hutU]. 3 551 49.92 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 Pfam PF01175 Urocanase 8 542 7.2E-252 T 09-03-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 ProSitePatterns PS01233 Urocanase signature. 437 452 - T 09-03-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 Gene3D G3DSA:3.40.1770.10 6 137 1.8E-152 T 09-03-2017 UA74_RS26520 eb4f0b02d3e99e8feb145414f62a5b5e 553 Gene3D G3DSA:3.40.1770.10 355 548 1.8E-152 T 09-03-2017 UA74_RS14960 303f8083c1e39c2cbf81241f5de75a9f 308 Gene3D G3DSA:3.90.1200.10 101 267 2.2E-34 T 09-03-2017 UA74_RS14960 303f8083c1e39c2cbf81241f5de75a9f 308 SUPERFAMILY SSF56112 1 269 3.21E-44 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS14960 303f8083c1e39c2cbf81241f5de75a9f 308 Pfam PF01636 Phosphotransferase enzyme family 29 258 8.1E-36 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 Pfam PF00664 ABC transporter transmembrane region 15 277 1.1E-16 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 SUPERFAMILY SSF90123 3 311 4.58E-43 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 SUPERFAMILY SSF52540 319 563 2.49E-79 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 Gene3D G3DSA:3.40.50.300 327 558 6.1E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 Pfam PF00005 ABC transporter 344 492 3.8E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 SMART SM00382 353 538 5.6E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16615 090cec10bd4a7fe10bc7343fd189aec7 576 Gene3D G3DSA:1.20.1560.10 3 316 9.4E-40 T 09-03-2017 UA74_RS24640 8f9260f4d13725997e6de98fb6fea822 229 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 23 228 3.0E-54 T 09-03-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 UA74_RS24640 8f9260f4d13725997e6de98fb6fea822 229 Gene3D G3DSA:3.40.50.620 19 200 1.7E-50 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS24640 8f9260f4d13725997e6de98fb6fea822 229 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 204 1.1E-40 T 09-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 UA74_RS24640 8f9260f4d13725997e6de98fb6fea822 229 PIRSF PIRSF000857 7 229 3.4E-88 T 09-03-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 UA74_RS24640 8f9260f4d13725997e6de98fb6fea822 229 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 41 227 8.5E-71 T 09-03-2017 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 UA74_RS24640 8f9260f4d13725997e6de98fb6fea822 229 SUPERFAMILY SSF52402 19 193 9.77E-41 T 09-03-2017 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 358 40.44 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 Pfam PF01820 D-ala D-ala ligase N-terminus 7 134 4.2E-35 T 09-03-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 SUPERFAMILY SSF56059 145 359 5.72E-56 T 09-03-2017 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 357 7.7E-108 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 Gene3D G3DSA:3.30.1490.20 168 225 5.3E-22 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 PIRSF PIRSF039102 3 363 1.2E-109 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 Pfam PF07478 D-ala D-ala ligase C-terminus 152 355 6.4E-67 T 09-03-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 112 123 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 Gene3D G3DSA:3.30.470.20 227 360 2.0E-47 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 Gene3D G3DSA:3.40.50.20 4 134 1.5E-38 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 SUPERFAMILY SSF52440 5 144 1.82E-36 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS25980 ffadbf92da2ca9f92d96647d0e7e289d 365 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 300 328 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS02745 cb763c88575ed699c4a64ed2ef633b64 296 Gene3D G3DSA:3.90.550.10 2 261 5.3E-60 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS02745 cb763c88575ed699c4a64ed2ef633b64 296 Pfam PF00483 Nucleotidyl transferase 2 237 1.6E-60 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_RS02745 cb763c88575ed699c4a64ed2ef633b64 296 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 1.8E-138 T 09-03-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 UA74_RS02745 cb763c88575ed699c4a64ed2ef633b64 296 SUPERFAMILY SSF53448 2 285 6.47E-83 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS01510 e7033ff808b6e33ad00e43cf768de2f3 184 Gene3D G3DSA:3.40.50.2020 2 182 1.5E-80 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS01510 e7033ff808b6e33ad00e43cf768de2f3 184 SUPERFAMILY SSF53271 3 182 1.05E-52 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS01510 e7033ff808b6e33ad00e43cf768de2f3 184 Pfam PF00156 Phosphoribosyl transferase domain 18 164 4.8E-23 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_RS01510 e7033ff808b6e33ad00e43cf768de2f3 184 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 178 6.6E-67 T 09-03-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Pfam PF00270 DEAD/DEAH box helicase 42 190 1.9E-17 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SMART SM00490 352 442 1.3E-13 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Gene3D G3DSA:3.40.50.300 38 220 3.2E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Pfam PF00271 Helicase conserved C-terminal domain 363 442 7.6E-5 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SMART SM01142 836 1012 8.1E-64 T 09-03-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Gene3D G3DSA:3.40.50.300 298 323 6.2E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Gene3D G3DSA:3.40.50.300 365 451 6.2E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Pfam PF08148 DSHCT (NUC185) domain 839 1007 5.2E-38 T 09-03-2017 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SMART SM00487 36 218 2.7E-28 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SUPERFAMILY SSF52540 362 456 1.93E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SUPERFAMILY SSF52540 55 191 1.93E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13035 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SUPERFAMILY SSF52540 264 320 1.93E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Gene3D G3DSA:2.60.120.260 904 1029 6.0E-31 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 SUPERFAMILY SSF49785 905 1030 3.4E-23 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Gene3D G3DSA:2.60.40.670 711 790 6.2E-17 T 09-03-2017 IPR000601 PKD domain UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Pfam PF00801 PKD domain 722 782 2.5E-10 T 09-03-2017 IPR000601 PKD domain UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Gene3D G3DSA:2.120.10.30 249 708 8.6E-97 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Pfam PF03422 Carbohydrate binding module (family 6) 906 1029 4.0E-26 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 SUPERFAMILY SSF49299 706 793 4.19E-16 T 09-03-2017 IPR000601 PKD domain UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 SMART SM00606 898 1030 9.1E-28 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Pfam PF06439 Domain of Unknown Function (DUF1080) 1054 1232 4.5E-36 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Pfam PF07995 Glucose / Sorbosone dehydrogenase 269 541 1.2E-32 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 SUPERFAMILY SSF52317 15 232 4.12E-47 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Pfam PF06283 Trehalose utilisation 17 226 5.2E-85 T 09-03-2017 IPR029010 ThuA-like domain UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 Gene3D G3DSA:3.40.50.880 13 230 1.0E-41 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 SMART SM00089 708 794 7.7E-17 T 09-03-2017 IPR022409 PKD/Chitinase domain UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 SUPERFAMILY SSF50952 604 685 2.22E-21 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS27280 b3da543cd9739b7dc86ef64dd7aa4dff 1599 SUPERFAMILY SSF50952 251 569 2.22E-21 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS27005 3f171b9f1f37d76e53a58bcb37e98206 172 Pfam PF04138 GtrA-like protein 27 158 1.1E-20 T 09-03-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 SUPERFAMILY SSF56059 3 228 4.66E-71 T 09-03-2017 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 388 4.7E-129 T 09-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 09-03-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 Gene3D G3DSA:3.30.470.20 88 231 3.1E-53 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 Pfam PF08442 ATP-grasp domain 2 194 6.1E-71 T 09-03-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 Gene3D G3DSA:3.30.1490.20 22 87 2.2E-18 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 Gene3D G3DSA:3.40.50.261 232 388 1.3E-52 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 389 41.026 T 09-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 Pfam PF00549 CoA-ligase 256 368 8.7E-13 T 09-03-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 PIRSF PIRSF001554 1 391 1.8E-138 T 09-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_RS27860 03b6651349e5475815463e9d77566dee 392 SUPERFAMILY SSF52210 231 388 1.1E-40 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 SUPERFAMILY SSF51445 206 639 3.0E-109 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Pfam PF00128 Alpha amylase, catalytic domain 296 363 6.2E-8 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Gene3D G3DSA:2.60.40.1180 644 745 1.4E-34 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 122 746 40.651 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 SUPERFAMILY SSF51011 644 745 1.26E-27 T 09-03-2017 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 SMART SM00642 275 615 1.9E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 146 232 3.0E-14 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 130 743 8.9E-247 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Gene3D G3DSA:2.60.40.10 134 246 2.8E-26 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Gene3D G3DSA:2.60.40.10 26 124 4.7E-11 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 SUPERFAMILY SSF81296 28 138 1.01E-11 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Gene3D G3DSA:3.20.20.80 263 631 1.1E-88 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 PIRSF PIRSF000463 18 746 5.9E-249 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07610 8891481030c18dc01446f64a1aebe70d 746 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 648 745 4.8E-17 T 09-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 UA74_RS12545 d382b9c13e54105232a76380f982b7b6 201 ProSitePatterns PS00194 Thioredoxin family active site. 88 106 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_RS12545 d382b9c13e54105232a76380f982b7b6 201 Pfam PF08534 Redoxin 62 159 1.2E-15 T 09-03-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 UA74_RS12545 d382b9c13e54105232a76380f982b7b6 201 SUPERFAMILY SSF52833 62 197 1.49E-25 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS12545 d382b9c13e54105232a76380f982b7b6 201 Gene3D G3DSA:3.40.30.10 10 197 3.0E-27 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.20.1580.10 588 714 1.9E-47 T 09-03-2017 UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 SUPERFAMILY SSF52540 22 70 1.33E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 SUPERFAMILY SSF52540 309 453 1.33E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 149 819 1.4E-241 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.10.8.280 185 296 5.9E-15 T 09-03-2017 UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Pfam PF00005 ABC transporter 518 754 1.5E-8 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:3.40.50.300 368 484 2.9E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:3.40.50.300 715 827 4.3E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:3.40.50.300 507 586 4.3E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:3.40.50.300 21 69 2.9E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 SMART SM00382 41 454 2.0 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 SMART SM00382 527 802 0.012 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 ProSitePatterns PS00211 ABC transporters family signature. 724 738 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 ProSitePatterns PS00211 ABC transporters family signature. 377 391 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 SUPERFAMILY SSF52540 514 804 3.59E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.20.1580.10 297 367 1.3E-44 T 09-03-2017 UA74_RS18890 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.20.1580.10 110 183 1.3E-44 T 09-03-2017 UA74_RS18660 431dc207a87bf7183c365db55790e006 139 Pfam PF14534 Domain of unknown function (DUF4440) 17 128 5.7E-12 T 09-03-2017 IPR027843 Domain of unknown function DUF4440 UA74_RS18660 431dc207a87bf7183c365db55790e006 139 SUPERFAMILY SSF54427 10 138 2.1E-37 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS18660 431dc207a87bf7183c365db55790e006 139 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 11 136 8.3E-40 T 09-03-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_RS18660 431dc207a87bf7183c365db55790e006 139 Gene3D G3DSA:3.10.450.50 2 136 1.3E-44 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS28385 67cead7f2c10a7949510ba652b723711 303 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS28385 67cead7f2c10a7949510ba652b723711 303 Pfam PF13732 Domain of unknown function (DUF4162) 215 297 4.3E-9 T 09-03-2017 IPR025302 Domain of unknown function DUF4162 UA74_RS28385 67cead7f2c10a7949510ba652b723711 303 Gene3D G3DSA:3.40.50.300 3 224 4.0E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28385 67cead7f2c10a7949510ba652b723711 303 Pfam PF00005 ABC transporter 21 161 5.4E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS28385 67cead7f2c10a7949510ba652b723711 303 SUPERFAMILY SSF52540 5 223 1.81E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28385 67cead7f2c10a7949510ba652b723711 303 SMART SM00382 30 209 1.1E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS02590 50040cfb66967f8d166dc430948beb9c 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 20.101 T 09-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 UA74_RS02590 50040cfb66967f8d166dc430948beb9c 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 8.2E-24 T 09-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 UA74_RS22665 94abbf2a80b3885d3b1763d1488359bf 68 Pfam PF04149 Domain of unknown function (DUF397) 10 63 1.3E-16 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS21590 9e8f3443a045218e70bf76decdbd9f80 394 SUPERFAMILY SSF63999 179 302 3.27E-10 T 09-03-2017 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 SUPERFAMILY SSF55424 343 465 3.78E-37 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 466 1.2E-164 T 09-03-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 SUPERFAMILY SSF51905 1 336 4.86E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 Gene3D G3DSA:3.50.50.60 4 143 2.4E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PIRSF PIRSF000350 1 462 6.4E-87 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 2.6E-35 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 2.6E-35 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 2.6E-35 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.6E-35 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 2.6E-35 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 Gene3D G3DSA:3.30.390.30 333 464 2.8E-42 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 09-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 Gene3D G3DSA:3.50.50.60 144 332 2.9E-49 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 3.3E-63 T 09-03-2017 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 7.5E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06215 cbf8af0035d5683e7178a265b38b8f69 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 1.3E-33 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS13700 594be087fb23053d34d9575e8c5d369a 192 Gene3D G3DSA:2.60.120.10 5 183 5.0E-43 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS13700 594be087fb23053d34d9575e8c5d369a 192 SUPERFAMILY SSF51182 5 183 1.71E-30 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS13700 594be087fb23053d34d9575e8c5d369a 192 Pfam PF03079 ARD/ARD' family 15 169 4.8E-29 T 09-03-2017 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 UA74_RS13700 594be087fb23053d34d9575e8c5d369a 192 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 177 34.599 T 09-03-2017 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Pfam PF03422 Carbohydrate binding module (family 6) 906 1027 1.2E-24 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SMART SM00089 709 792 9.1E-16 T 09-03-2017 IPR022409 PKD/Chitinase domain UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Gene3D G3DSA:3.40.50.880 31 258 1.4E-29 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SUPERFAMILY SSF49299 707 794 1.05E-17 T 09-03-2017 IPR000601 PKD domain UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SUPERFAMILY SSF50952 442 536 1.7E-18 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SUPERFAMILY SSF50952 264 412 1.7E-18 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SUPERFAMILY SSF50952 605 686 1.7E-18 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Gene3D G3DSA:2.60.40.670 709 794 4.0E-18 T 09-03-2017 IPR000601 PKD domain UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Pfam PF07995 Glucose / Sorbosone dehydrogenase 277 538 6.6E-33 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SUPERFAMILY SSF52317 29 257 8.93E-34 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Gene3D G3DSA:2.120.10.30 259 708 1.0E-97 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Pfam PF00801 PKD domain 714 779 2.9E-9 T 09-03-2017 IPR000601 PKD domain UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SMART SM00606 898 1028 6.8E-23 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Pfam PF06283 Trehalose utilisation 31 251 8.0E-58 T 09-03-2017 IPR029010 ThuA-like domain UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 SUPERFAMILY SSF49785 902 1027 1.68E-21 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS20730 6558fff366fa8a0db0177423fe11bfc8 1034 Gene3D G3DSA:2.60.120.260 901 1027 1.5E-29 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS20700 48a8c99ecbe561b3e539ebebde5d4411 293 Gene3D G3DSA:3.40.50.1010 1 167 1.8E-15 T 09-03-2017 IPR029060 PIN domain-like UA74_RS20700 48a8c99ecbe561b3e539ebebde5d4411 293 Pfam PF01936 NYN domain 3 165 1.0E-12 T 09-03-2017 IPR021139 NYN domain, limkain-b1-type UA74_RS04120 2ca1311df5ff82601f004487409f0f4d 337 Gene3D G3DSA:3.20.20.190 13 329 1.2E-85 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS04120 2ca1311df5ff82601f004487409f0f4d 337 SUPERFAMILY SSF51695 16 316 1.2E-59 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS04120 2ca1311df5ff82601f004487409f0f4d 337 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 21 310 9.6E-39 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_RS17000 a96bd105f6b366744619906ae3665677 329 Gene3D G3DSA:2.115.10.20 137 318 3.0E-6 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS17000 a96bd105f6b366744619906ae3665677 329 Gene3D G3DSA:2.115.10.20 76 136 1.3E-6 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS17000 a96bd105f6b366744619906ae3665677 329 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 31 6.8E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UA74_RS17000 a96bd105f6b366744619906ae3665677 329 SUPERFAMILY SSF75005 76 263 4.71E-17 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 232 460 8.2E-81 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 Pfam PF00364 Biotin-requiring enzyme 6 78 1.3E-19 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 Gene3D G3DSA:4.10.320.10 174 223 1.6E-14 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 SUPERFAMILY SSF52777 227 458 3.25E-79 T 09-03-2017 UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 Gene3D G3DSA:2.40.50.100 3 91 1.2E-23 T 09-03-2017 UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 Pfam PF02817 e3 binding domain 178 212 6.4E-11 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 SUPERFAMILY SSF51230 4 93 6.02E-24 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 SUPERFAMILY SSF47005 174 216 1.44E-9 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS30095 baedc40b413cea754becca9b4744dd37 462 Gene3D G3DSA:3.30.559.10 229 458 1.2E-82 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 PIRSF PIRSF000097 1 279 1.2E-77 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 Gene3D G3DSA:3.20.20.100 3 276 2.7E-95 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 122 139 3.1E-42 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 202 226 3.1E-42 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 89 107 3.1E-42 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 156 185 3.1E-42 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 33 57 3.1E-42 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 SUPERFAMILY SSF51430 3 272 4.98E-85 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS07925 537d8d7af448e782059fcfecc5ba78d0 291 Pfam PF00248 Aldo/keto reductase family 20 266 1.1E-43 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS13225 41a51cedfece9949772f04ff9282fd6a 347 Gene3D G3DSA:3.40.50.150 98 333 4.5E-70 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13225 41a51cedfece9949772f04ff9282fd6a 347 Pfam PF00891 O-methyltransferase 104 326 1.3E-50 T 09-03-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_RS13225 41a51cedfece9949772f04ff9282fd6a 347 Pfam PF16864 Dimerisation domain 16 76 7.0E-9 T 09-03-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_RS13225 41a51cedfece9949772f04ff9282fd6a 347 SUPERFAMILY SSF46785 12 92 1.94E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13225 41a51cedfece9949772f04ff9282fd6a 347 SUPERFAMILY SSF53335 95 327 4.55E-52 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13225 41a51cedfece9949772f04ff9282fd6a 347 PIRSF PIRSF005739 1 335 5.1E-58 T 09-03-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_RS13225 41a51cedfece9949772f04ff9282fd6a 347 Gene3D G3DSA:1.10.10.10 9 97 6.2E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18450 848ad5ac234c972eb080e98903445bb8 517 SUPERFAMILY SSF48452 4 126 1.66E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18450 848ad5ac234c972eb080e98903445bb8 517 Gene3D G3DSA:1.25.40.10 138 362 2.5E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18450 848ad5ac234c972eb080e98903445bb8 517 SUPERFAMILY SSF48452 142 321 1.38E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18450 848ad5ac234c972eb080e98903445bb8 517 Pfam PF13424 Tetratricopeptide repeat 136 202 1.9E-7 T 09-03-2017 UA74_RS18450 848ad5ac234c972eb080e98903445bb8 517 Gene3D G3DSA:1.25.40.10 4 114 3.7E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19090 9dd881027c72e895cd2dd817bdafad3a 352 Pfam PF01032 FecCD transport family 24 344 2.0E-88 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS19090 9dd881027c72e895cd2dd817bdafad3a 352 Gene3D G3DSA:1.10.3470.10 14 346 3.9E-97 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS19090 9dd881027c72e895cd2dd817bdafad3a 352 SUPERFAMILY SSF81345 10 345 3.92E-73 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 318 731 5.1E-137 T 09-03-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 Gene3D G3DSA:2.70.98.40 3 265 1.2E-82 T 09-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 PIRSF PIRSF036289 1 799 2.6E-201 T 09-03-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 Gene3D G3DSA:1.50.10.10 312 715 9.2E-123 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 SUPERFAMILY SSF74650 3 264 1.38E-66 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 9 263 5.0E-69 T 09-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 Gene3D G3DSA:2.60.420.10 721 772 8.6E-7 T 09-03-2017 UA74_RS20440 96331840d07ac3d789b2ebee7ad488ec 816 SUPERFAMILY SSF48208 270 772 3.32E-102 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS07720 92c2f9f279d0d8fdcf3a9d19804bcb04 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 68 7.4E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS07720 92c2f9f279d0d8fdcf3a9d19804bcb04 204 Gene3D G3DSA:1.10.357.10 69 198 3.2E-18 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS07720 92c2f9f279d0d8fdcf3a9d19804bcb04 204 SUPERFAMILY SSF46689 14 93 7.18E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07720 92c2f9f279d0d8fdcf3a9d19804bcb04 204 SUPERFAMILY SSF48498 89 198 2.33E-14 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS07720 92c2f9f279d0d8fdcf3a9d19804bcb04 204 Gene3D G3DSA:1.10.10.60 15 68 7.9E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 87 3.1E-5 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 PIRSF PIRSF016578 1 391 2.1E-34 T 09-03-2017 UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 Gene3D G3DSA:1.10.540.10 6 106 4.9E-28 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 370 5.0E-15 T 09-03-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 Gene3D G3DSA:1.20.140.10 206 391 1.4E-48 T 09-03-2017 UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 SUPERFAMILY SSF56645 14 213 6.94E-37 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 SUPERFAMILY SSF47203 234 390 4.67E-17 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS13720 83912254e876cd0e4d8785512b255cfb 395 Gene3D G3DSA:2.40.110.10 121 205 1.4E-17 T 09-03-2017 UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 SUPERFAMILY SSF53383 19 393 3.68E-124 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 Gene3D G3DSA:3.90.1150.10 12 62 3.0E-35 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 Gene3D G3DSA:3.90.1150.10 305 394 3.0E-35 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 19 393 3.6E-141 T 09-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 16 394 43.675 T 09-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 Pfam PF00202 Aminotransferase class-III 26 388 1.1E-110 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 Gene3D G3DSA:3.40.640.10 63 302 7.7E-91 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS21680 438114c1f0d85e74d182499213c6d533 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS18840 1f8db5a7dec9e5dd3f224090d5588964 346 SUPERFAMILY SSF51569 19 326 1.26E-30 T 09-03-2017 UA74_RS18840 1f8db5a7dec9e5dd3f224090d5588964 346 Gene3D G3DSA:3.20.20.70 19 328 9.0E-46 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS18840 1f8db5a7dec9e5dd3f224090d5588964 346 SMART SM01130 15 329 2.1E-9 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS18840 1f8db5a7dec9e5dd3f224090d5588964 346 Pfam PF00701 Dihydrodipicolinate synthetase family 22 226 2.1E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 Gene3D G3DSA:3.50.50.60 284 321 1.5E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 Gene3D G3DSA:3.50.50.60 4 180 1.5E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 SUPERFAMILY SSF51905 273 375 2.18E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 SUPERFAMILY SSF51905 5 177 2.18E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.4E-7 T 09-03-2017 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.4E-7 T 09-03-2017 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 1.4E-7 T 09-03-2017 UA74_RS05825 7c34744e2b419af19430721917e8efa0 413 Pfam PF01494 FAD binding domain 5 321 1.0E-19 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 Gene3D G3DSA:1.20.1560.10 30 351 4.1E-72 T 09-03-2017 UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 ProSitePatterns PS00211 ABC transporters family signature. 519 533 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 SUPERFAMILY SSF52540 354 618 4.6E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 SMART SM00382 407 593 6.0E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 Pfam PF00005 ABC transporter 398 547 1.5E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 Pfam PF00664 ABC transporter transmembrane region 47 316 2.0E-40 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 SUPERFAMILY SSF90123 31 351 1.96E-72 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS14300 a713e3de7ba78ba7400a2767a939c294 642 Gene3D G3DSA:3.40.50.300 363 611 6.5E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07080 0f34b2b02db816c058ca1745dd10535f 358 SUPERFAMILY SSF53686 12 336 5.11E-102 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS07080 0f34b2b02db816c058ca1745dd10535f 358 Gene3D G3DSA:3.40.50.1100 67 151 1.5E-42 T 09-03-2017 UA74_RS07080 0f34b2b02db816c058ca1745dd10535f 358 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 59 72 - T 09-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UA74_RS07080 0f34b2b02db816c058ca1745dd10535f 358 PIRSF PIRSF038945 1 357 9.0E-164 T 09-03-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 UA74_RS07080 0f34b2b02db816c058ca1745dd10535f 358 Gene3D G3DSA:3.40.50.1100 152 334 8.9E-50 T 09-03-2017 UA74_RS07080 0f34b2b02db816c058ca1745dd10535f 358 TIGRFAM TIGR00260 thrC: threonine synthase 17 332 3.8E-90 T 09-03-2017 IPR004450 Threonine synthase-like UA74_RS07080 0f34b2b02db816c058ca1745dd10535f 358 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 31 325 1.4E-76 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1355 1370 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF52151 720 801 1.8E-61 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF52151 538 661 1.8E-61 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 404 1.2E-45 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF00550 Phosphopantetheine attachment site 1331 1396 1.3E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF55048 660 718 2.75E-6 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF51735 869 1052 8.06E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF00698 Acyl transferase domain 541 779 1.5E-40 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF53901 32 401 2.96E-103 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.50.720 1062 1241 1.5E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:1.10.1200.10 1326 1401 3.4E-25 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.366.10 537 655 1.8E-62 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.366.10 718 811 1.8E-62 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 281 9.0E-86 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.47.10 37 293 1.7E-87 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF47336 1319 1406 7.07E-24 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF08659 KR domain 1063 1236 4.1E-54 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1063 1238 6.2E-45 T 09-03-2017 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF51735 1060 1271 8.11E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM01294 1329 1396 1.6E-6 T 09-03-2017 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.47.10 294 457 1.0E-66 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 541 808 3.0E-82 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00825 Beta-ketoacyl synthase 37 457 2.0E-209 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00823 Phosphopantetheine attachment site 1328 1400 4.0E-32 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17350 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 407 521 1.8E-13 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.1E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 7.4E-15 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 7.4E-15 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 7.4E-15 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 Pfam PF00072 Response regulator receiver domain 4 114 7.4E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 SUPERFAMILY SSF52172 1 176 2.26E-32 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 SMART SM00448 2 114 4.1E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 Gene3D G3DSA:3.40.50.2300 1 155 3.1E-39 T 09-03-2017 UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 Gene3D G3DSA:1.10.10.10 156 212 1.7E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27330 efa595f0b1368d387b26df530b126fe5 214 SMART SM00421 150 207 1.9E-26 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 SMART SM00829 46 412 1.1E-10 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 Pfam PF00107 Zinc-binding dehydrogenase 233 377 1.5E-30 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 SUPERFAMILY SSF50129 49 227 8.33E-29 T 09-03-2017 IPR011032 GroES-like UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 Gene3D G3DSA:3.90.180.10 48 228 5.3E-35 T 09-03-2017 IPR011032 GroES-like UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 425 7.0E-173 T 09-03-2017 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 222 243 - T 09-03-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 65 187 1.1E-7 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 Gene3D G3DSA:3.40.50.720 229 361 1.5E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16575 f7bc0bf479b3fc781f27f25ecc79f366 448 SUPERFAMILY SSF51735 192 381 1.78E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26345 88fc95b36adb44dd98e1116007ee99ec 530 SUPERFAMILY SSF103473 479 505 1.31E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS26345 88fc95b36adb44dd98e1116007ee99ec 530 SUPERFAMILY SSF103473 8 209 1.31E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS26345 88fc95b36adb44dd98e1116007ee99ec 530 SUPERFAMILY SSF103473 256 427 1.31E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS26345 88fc95b36adb44dd98e1116007ee99ec 530 Gene3D G3DSA:1.20.1250.20 20 204 1.1E-26 T 09-03-2017 UA74_RS26345 88fc95b36adb44dd98e1116007ee99ec 530 Gene3D G3DSA:1.20.1250.20 270 427 1.9E-13 T 09-03-2017 UA74_RS26345 88fc95b36adb44dd98e1116007ee99ec 530 Pfam PF07690 Major Facilitator Superfamily 31 417 2.1E-46 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS24325 2f835c9b81880977cb3b6eb18b1a3ab4 309 Gene3D G3DSA:1.10.3720.10 23 301 1.2E-48 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24325 2f835c9b81880977cb3b6eb18b1a3ab4 309 SUPERFAMILY SSF161098 24 306 6.64E-47 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24325 2f835c9b81880977cb3b6eb18b1a3ab4 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 301 2.0E-12 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 SMART SM00861 375 555 6.7E-74 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 SUPERFAMILY SSF52518 17 344 6.12E-103 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 Pfam PF02779 Transketolase, pyrimidine binding domain 374 554 8.3E-50 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 Gene3D G3DSA:3.40.50.920 566 694 6.1E-46 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 Gene3D G3DSA:3.40.50.970 20 344 3.8E-111 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 TIGRFAM TIGR00232 tktlase_bact: transketolase 25 690 6.2E-242 T 09-03-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 Pfam PF02780 Transketolase, C-terminal domain 577 684 3.5E-11 T 09-03-2017 IPR033248 Transketolase, C-terminal domain UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 Gene3D G3DSA:3.40.50.970 354 561 3.2E-78 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 23 358 2.0E-138 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 SUPERFAMILY SSF52922 560 694 1.7E-40 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 SUPERFAMILY SSF52518 366 556 5.58E-69 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12510 646a3c195c85933b1a95e8254f720e42 698 ProSitePatterns PS00802 Transketolase signature 2. 497 513 - T 09-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS26400 6ea3abcafd2387fce388ff006773d0e1 105 SUPERFAMILY SSF54913 2 102 6.67E-35 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta UA74_RS26400 6ea3abcafd2387fce388ff006773d0e1 105 Gene3D G3DSA:3.30.70.830 2 103 1.9E-36 T 09-03-2017 UA74_RS26400 6ea3abcafd2387fce388ff006773d0e1 105 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 5.8E-34 T 09-03-2017 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 UA74_RS04785 f7f317ce39cd72f4ce854a30f1f69979 264 Gene3D G3DSA:3.90.1200.10 96 186 2.4E-7 T 09-03-2017 UA74_RS04785 f7f317ce39cd72f4ce854a30f1f69979 264 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 6 259 2.1E-79 T 09-03-2017 IPR013402 Conserved hypothetical protein CHP02569 UA74_RS04785 f7f317ce39cd72f4ce854a30f1f69979 264 SUPERFAMILY SSF56112 35 199 2.04E-11 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF47336 914 1011 7.85E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.90.1150.10 1383 1471 2.6E-26 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.90.1150.10 1050 1122 2.6E-26 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00550 Phosphopantetheine attachment site 923 989 7.9E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00668 Condensation domain 1510 1794 9.0E-25 T 09-03-2017 IPR001242 Condensation domain UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00698 Acyl transferase domain 583 781 1.8E-18 T 09-03-2017 IPR014043 Acyl transferase UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF52151 522 647 6.54E-32 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF52151 707 801 6.54E-32 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 383 2.9E-34 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF52777 1712 1908 1.45E-9 T 09-03-2017 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.47.10 273 435 2.9E-52 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00202 Aminotransferase class-III 1082 1446 8.4E-43 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.640.10 1125 1379 3.4E-53 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF52777 1507 1700 7.67E-26 T 09-03-2017 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 1284 1320 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 173 189 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 260 4.6E-56 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SMART SM00823 Phosphopantetheine attachment site 921 993 5.5E-4 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 387 498 3.3E-14 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 525 842 1.7E-18 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SMART SM00825 Beta-ketoacyl synthase 5 435 6.3E-118 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:1.10.1200.10 910 989 2.7E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.366.10 705 808 1.4E-33 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.366.10 514 641 1.4E-33 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF53383 1062 1471 4.65E-76 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF55048 645 705 9.42E-5 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.47.10 6 272 1.2E-62 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF53901 156 379 1.06E-69 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF53901 410 431 1.06E-69 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05215 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF53901 2 120 1.06E-69 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS19045 b08edf2437c357e85aaef5b56237fc7d 299 Gene3D G3DSA:1.10.150.130 21 98 5.4E-9 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS19045 b08edf2437c357e85aaef5b56237fc7d 299 Gene3D G3DSA:1.10.443.10 115 289 1.3E-34 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS19045 b08edf2437c357e85aaef5b56237fc7d 299 Pfam PF00589 Phage integrase family 117 289 1.6E-30 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS19045 b08edf2437c357e85aaef5b56237fc7d 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 97 3.8E-6 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_RS19045 b08edf2437c357e85aaef5b56237fc7d 299 SUPERFAMILY SSF56349 11 288 1.5E-34 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 SUPERFAMILY SSF52980 1384 1488 5.9E-8 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 Pfam PF13245 Part of AAA domain 410 461 9.4E-10 T 09-03-2017 UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 Gene3D G3DSA:3.40.50.300 1187 1349 6.7E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 Gene3D G3DSA:3.40.50.300 1089 1186 4.2E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 Gene3D G3DSA:3.40.50.300 386 508 4.2E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 Pfam PF13087 AAA domain 1161 1344 7.2E-15 T 09-03-2017 UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 SUPERFAMILY SSF52540 1073 1349 4.82E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 SUPERFAMILY SSF52540 397 465 4.82E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24140 670ee9e2b0af5a15c5ad76d6911decd2 1606 SUPERFAMILY SSF52540 500 542 4.82E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 Gene3D G3DSA:2.40.128.30 24 146 4.4E-44 T 09-03-2017 IPR005468 Avidin/streptavidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 SUPERFAMILY SSF50876 26 144 8.9E-32 T 09-03-2017 IPR005468 Avidin/streptavidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 Pfam PF01382 Avidin family 26 138 6.3E-24 T 09-03-2017 IPR005468 Avidin/streptavidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 PRINTS PR00709 Avidin signature 112 123 6.1E-24 T 09-03-2017 IPR005469 Avidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 PRINTS PR00709 Avidin signature 96 106 6.1E-24 T 09-03-2017 IPR005469 Avidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 PRINTS PR00709 Avidin signature 26 40 6.1E-24 T 09-03-2017 IPR005469 Avidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 PRINTS PR00709 Avidin signature 46 54 6.1E-24 T 09-03-2017 IPR005469 Avidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 PRINTS PR00709 Avidin signature 128 144 6.1E-24 T 09-03-2017 IPR005469 Avidin UA74_RS13930 437871b4a1cccd3442316b9e492703fe 161 PRINTS PR00709 Avidin signature 74 86 6.1E-24 T 09-03-2017 IPR005469 Avidin UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 Pfam PF00176 SNF2 family N-terminal domain 511 774 1.1E-49 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 Gene3D G3DSA:3.40.50.300 487 654 9.2E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 SMART SM00487 488 669 6.9E-30 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 SUPERFAMILY SSF52540 474 706 3.19E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 SMART SM00490 820 902 6.2E-27 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 Gene3D G3DSA:3.40.50.300 787 937 8.0E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 Pfam PF12419 SNF2 Helicase protein 318 446 9.2E-31 T 09-03-2017 IPR022138 Helicase SWF/SNF-related UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 Pfam PF00271 Helicase conserved C-terminal domain 795 902 3.7E-19 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS15590 00ff550bb5a9167ebf5b4a03a98ac4be 962 SUPERFAMILY SSF52540 713 957 1.11E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05285 6603611912879a52802a9f90f96c2fa1 317 Gene3D G3DSA:2.60.120.620 7 274 1.1E-53 T 09-03-2017 UA74_RS05285 6603611912879a52802a9f90f96c2fa1 317 TIGRFAM TIGR01762 chlorin-enz: chlorinating enzyme 10 304 2.4E-134 T 09-03-2017 IPR010092 Chlorinating enzyme UA74_RS05285 6603611912879a52802a9f90f96c2fa1 317 SUPERFAMILY SSF51197 10 306 5.22E-53 T 09-03-2017 UA74_RS05285 6603611912879a52802a9f90f96c2fa1 317 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 20 250 2.5E-36 T 09-03-2017 IPR008775 Phytanoyl-CoA dioxygenase UA74_RS04695 e1ed8bbcc8058945004d656bf1593f33 172 Pfam PF04542 Sigma-70 region 2 8 72 1.5E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04695 e1ed8bbcc8058945004d656bf1593f33 172 Gene3D G3DSA:1.10.1740.10 3 73 3.7E-12 T 09-03-2017 UA74_RS04695 e1ed8bbcc8058945004d656bf1593f33 172 Pfam PF08281 Sigma-70, region 4 100 153 1.1E-17 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04695 e1ed8bbcc8058945004d656bf1593f33 172 Gene3D G3DSA:1.10.10.10 99 155 4.8E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04695 e1ed8bbcc8058945004d656bf1593f33 172 SUPERFAMILY SSF88946 3 78 4.71E-13 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04695 e1ed8bbcc8058945004d656bf1593f33 172 SUPERFAMILY SSF88659 94 155 1.57E-16 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04695 e1ed8bbcc8058945004d656bf1593f33 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 155 6.4E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS25420 32fd99bdeeb1b35f1898b6f4e1060055 285 SUPERFAMILY SSF102705 4 276 1.31E-73 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 UA74_RS25420 32fd99bdeeb1b35f1898b6f4e1060055 285 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 268 6.3E-46 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 UA74_RS25420 32fd99bdeeb1b35f1898b6f4e1060055 285 Gene3D G3DSA:3.40.1390.30 116 223 1.4E-30 T 09-03-2017 UA74_RS25420 32fd99bdeeb1b35f1898b6f4e1060055 285 Gene3D G3DSA:3.40.1390.30 4 115 5.3E-42 T 09-03-2017 UA74_RS25420 32fd99bdeeb1b35f1898b6f4e1060055 285 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 258 2.0E-63 T 09-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 UA74_RS06265 2dc068e1ab48c001d22f4ee7cda9fbde 191 Pfam PF00857 Isochorismatase family 4 184 8.4E-32 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS06265 2dc068e1ab48c001d22f4ee7cda9fbde 191 SUPERFAMILY SSF52499 3 184 1.11E-45 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS06265 2dc068e1ab48c001d22f4ee7cda9fbde 191 Gene3D G3DSA:3.40.50.850 3 183 4.6E-56 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS04765 2502da0e4a5cd2c4fa8238819f7e14e7 444 PRINTS PR00111 Alpha/beta hydrolase fold signature 164 179 8.4E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS04765 2502da0e4a5cd2c4fa8238819f7e14e7 444 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 236 8.4E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS04765 2502da0e4a5cd2c4fa8238819f7e14e7 444 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 222 8.4E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS04765 2502da0e4a5cd2c4fa8238819f7e14e7 444 Gene3D G3DSA:3.40.50.1820 108 401 4.2E-58 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS04765 2502da0e4a5cd2c4fa8238819f7e14e7 444 SUPERFAMILY SSF53474 111 401 3.41E-55 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS04765 2502da0e4a5cd2c4fa8238819f7e14e7 444 Pfam PF00561 alpha/beta hydrolase fold 142 391 1.1E-22 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS25525 85b88096b7b5bb38db6c1720ce2fa247 185 Pfam PF14016 Protein of unknown function (DUF4232) 45 164 7.6E-14 T 09-03-2017 IPR025326 Protein of unknown function DUF4232 UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 16 437 93.65 T 09-03-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 17 430 1.9E-175 T 09-03-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 Gene3D G3DSA:3.40.640.10 83 327 4.0E-74 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 283 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 Gene3D G3DSA:3.90.1150.10 331 433 2.6E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 Gene3D G3DSA:3.90.1150.10 13 82 2.6E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 SUPERFAMILY SSF53383 14 433 5.27E-114 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS02355 7718a6c43932b2acbb90b53559b64266 446 Pfam PF00202 Aminotransferase class-III 46 430 1.4E-80 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS29220 178fef3b3a2e860063c44309eed283ec 304 SUPERFAMILY SSF103481 48 147 8.89E-9 T 09-03-2017 UA74_RS29220 178fef3b3a2e860063c44309eed283ec 304 Pfam PF00892 EamA-like transporter family 159 288 5.0E-20 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS29220 178fef3b3a2e860063c44309eed283ec 304 Pfam PF00892 EamA-like transporter family 14 144 2.7E-12 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS29220 178fef3b3a2e860063c44309eed283ec 304 SUPERFAMILY SSF103481 191 294 4.05E-11 T 09-03-2017 UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 SUPERFAMILY SSF52922 607 736 1.14E-27 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 Pfam PF00676 Dehydrogenase E1 component 71 354 2.3E-26 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 SMART SM00861 401 582 1.1E-41 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 Gene3D G3DSA:3.40.50.970 32 371 6.2E-82 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 SUPERFAMILY SSF52518 400 589 5.89E-46 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 Gene3D G3DSA:3.40.50.920 617 732 8.2E-27 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 Pfam PF02780 Transketolase, C-terminal domain 610 716 4.1E-21 T 09-03-2017 IPR033248 Transketolase, C-terminal domain UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 SUPERFAMILY SSF52518 34 357 8.42E-49 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 Pfam PF02779 Transketolase, pyrimidine binding domain 402 574 1.3E-25 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS21435 c370bcd4859585f9e3a7bac7d386b177 737 Gene3D G3DSA:3.40.50.970 401 585 4.0E-51 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS23535 49f654a79cf687c28f793b68a221abd8 99 Pfam PF02467 Transcription factor WhiB 17 87 7.0E-22 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS23535 49f654a79cf687c28f793b68a221abd8 99 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.508 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS13230 244caf8a23104ff3e5ae2dc0657f2af3 511 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS13230 244caf8a23104ff3e5ae2dc0657f2af3 511 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS13230 244caf8a23104ff3e5ae2dc0657f2af3 511 Gene3D G3DSA:3.30.200.20 12 90 7.5E-21 T 09-03-2017 UA74_RS13230 244caf8a23104ff3e5ae2dc0657f2af3 511 SUPERFAMILY SSF56112 11 272 8.23E-66 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS13230 244caf8a23104ff3e5ae2dc0657f2af3 511 Gene3D G3DSA:1.10.510.10 91 269 2.3E-45 T 09-03-2017 UA74_RS13230 244caf8a23104ff3e5ae2dc0657f2af3 511 Pfam PF00069 Protein kinase domain 20 269 2.7E-48 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS13230 244caf8a23104ff3e5ae2dc0657f2af3 511 SMART SM00220 20 274 1.1E-53 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS19240 12724b6367d538c7162c4fcffb96b445 305 SUPERFAMILY SSF51735 5 231 1.42E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19240 12724b6367d538c7162c4fcffb96b445 305 Pfam PF00106 short chain dehydrogenase 7 146 1.3E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19240 12724b6367d538c7162c4fcffb96b445 305 Gene3D G3DSA:3.40.50.720 182 244 3.1E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19240 12724b6367d538c7162c4fcffb96b445 305 Gene3D G3DSA:3.40.50.720 4 150 3.1E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21100 c6d6c4d43208e4c923b2fad8ed258184 297 Gene3D G3DSA:3.20.20.150 42 234 3.4E-23 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS21100 c6d6c4d43208e4c923b2fad8ed258184 297 SUPERFAMILY SSF51658 41 234 8.29E-23 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS21100 c6d6c4d43208e4c923b2fad8ed258184 297 Pfam PF01261 Xylose isomerase-like TIM barrel 46 219 6.2E-17 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS14565 b3459ac8b1a8a444caf785b5dfce9ce8 256 Gene3D G3DSA:3.40.50.1820 12 249 5.1E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14565 b3459ac8b1a8a444caf785b5dfce9ce8 256 SUPERFAMILY SSF53474 9 248 2.53E-53 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14565 b3459ac8b1a8a444caf785b5dfce9ce8 256 Pfam PF00975 Thioesterase domain 24 247 1.2E-53 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS14565 b3459ac8b1a8a444caf785b5dfce9ce8 256 SMART SM00824 Thioesterase 26 248 1.6E-4 T 09-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_RS23900 e8ea4df594fa119a8dedd2fb26750b02 414 SUPERFAMILY SSF51126 12 413 8.77E-76 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS23900 e8ea4df594fa119a8dedd2fb26750b02 414 SMART SM00656 105 337 3.1E-46 T 09-03-2017 IPR002022 Pectate lyase/Amb allergen UA74_RS23900 e8ea4df594fa119a8dedd2fb26750b02 414 Gene3D G3DSA:2.160.20.10 13 413 7.0E-115 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS23900 e8ea4df594fa119a8dedd2fb26750b02 414 Pfam PF00544 Pectate lyase 120 331 1.0E-50 T 09-03-2017 IPR002022 Pectate lyase/Amb allergen UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 874 1.7E-18 T 09-03-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 53 64 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:1.10.730.10 568 744 3.5E-52 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF47323 580 822 5.05E-47 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:3.90.740.10 214 342 1.1E-44 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 25 433 3.7E-142 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 445 565 1.6E-45 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 TIGRFAM TIGR00422 valS: valine--tRNA ligase 13 852 1.7E-301 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:1.10.287.380 805 874 2.7E-8 T 09-03-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Hamap MF_02004 Valine--tRNA ligase [valS]. 12 875 15.07 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Pfam PF08264 Anticodon-binding domain of tRNA 610 752 1.0E-37 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF50677 200 342 3.66E-54 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF52374 349 577 3.03E-134 T 09-03-2017 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF52374 3 200 3.03E-134 T 09-03-2017 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 46 57 3.9E-38 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 3.9E-38 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 238 255 3.9E-38 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 3.9E-38 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 354 367 3.9E-38 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF46589 810 874 4.81E-13 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:3.40.50.620 349 566 4.0E-138 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS08220 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:3.40.50.620 15 203 4.0E-138 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Pfam PF00512 His Kinase A (phospho-acceptor) domain 657 723 4.8E-11 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Pfam PF00582 Universal stress protein family 250 371 1.9E-6 T 09-03-2017 IPR006016 UspA GO:0006950 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Gene3D G3DSA:3.40.50.300 21 229 5.5E-97 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 SMART SM00387 765 877 2.0E-25 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Gene3D G3DSA:3.30.565.10 711 878 3.2E-31 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 SUPERFAMILY SSF47384 646 724 1.35E-11 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Gene3D G3DSA:1.20.120.620 392 495 2.0E-21 T 09-03-2017 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 SUPERFAMILY SSF55874 714 875 3.67E-32 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Gene3D G3DSA:1.10.287.130 647 710 1.1E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 SUPERFAMILY SSF52402 251 372 9.63E-13 T 09-03-2017 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Pfam PF13493 Domain of unknown function (DUF4118) 397 502 3.8E-24 T 09-03-2017 IPR025201 Sensor protein KdpD, transmembrane domain UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 SMART SM00388 656 724 8.7E-13 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 21 230 1.1E-96 T 09-03-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 766 875 1.8E-17 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 861 874 3.7E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 804 818 3.7E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 822 832 3.7E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 837 855 3.7E-10 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS25735 3ea92987ac3cbc3ae1482f65b6aa3bd4 882 Gene3D G3DSA:3.40.50.620 245 372 3.3E-14 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 SUPERFAMILY SSF48452 60 224 4.49E-38 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 Pfam PF03704 Bacterial transcriptional activator domain 62 207 9.6E-35 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 SUPERFAMILY SSF52540 227 469 9.78E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 Gene3D G3DSA:3.40.50.300 232 352 1.1E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 Gene3D G3DSA:1.25.40.10 70 186 1.4E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 SUPERFAMILY SSF46894 2 57 1.05E-6 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 SMART SM01043 62 207 4.5E-42 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 Gene3D G3DSA:1.10.10.10 2 56 9.0E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03310 8a0145203dbf6dbf811e064525095747 864 Pfam PF00486 Transcriptional regulatory protein, C terminal 1 45 3.4E-5 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 Pfam PF01479 S4 domain 2 43 2.0E-13 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 SMART SM00363 1 62 2.6E-11 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 Pfam PF00849 RNA pseudouridylate synthase 62 194 1.9E-22 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 SUPERFAMILY SSF55174 1 57 2.55E-13 T 09-03-2017 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 SUPERFAMILY SSF55120 53 236 3.96E-45 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 09-03-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 Gene3D G3DSA:3.10.290.10 1 63 1.8E-22 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS21505 8f06c7117898a31afdaf4d86eafa0e41 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 225 3.7E-45 T 09-03-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 UA74_RS22805 31a3525a909b197f5ef3e1c0184708a6 247 Pfam PF01614 Bacterial transcriptional regulator 117 241 1.5E-33 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS22805 31a3525a909b197f5ef3e1c0184708a6 247 SUPERFAMILY SSF46785 3 73 1.86E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22805 31a3525a909b197f5ef3e1c0184708a6 247 Pfam PF09339 IclR helix-turn-helix domain 4 52 2.9E-10 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS22805 31a3525a909b197f5ef3e1c0184708a6 247 Gene3D G3DSA:1.10.10.10 2 71 2.0E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22805 31a3525a909b197f5ef3e1c0184708a6 247 SMART SM00346 2 89 5.5E-25 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS22805 31a3525a909b197f5ef3e1c0184708a6 247 SUPERFAMILY SSF55781 57 245 8.5E-51 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22805 31a3525a909b197f5ef3e1c0184708a6 247 Gene3D G3DSA:3.30.450.40 72 246 4.3E-57 T 09-03-2017 IPR029016 GAF domain-like UA74_RS13050 53afa6dde4446212b239e5493572f103 320 SMART SM00475 3 287 4.8E-76 T 09-03-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 UA74_RS13050 53afa6dde4446212b239e5493572f103 320 SUPERFAMILY SSF47807 198 310 6.13E-19 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 UA74_RS13050 53afa6dde4446212b239e5493572f103 320 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 188 6.2E-45 T 09-03-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 UA74_RS13050 53afa6dde4446212b239e5493572f103 320 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 197 284 2.2E-16 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 UA74_RS13050 53afa6dde4446212b239e5493572f103 320 Gene3D G3DSA:1.10.150.20 198 270 9.2E-16 T 09-03-2017 UA74_RS13050 53afa6dde4446212b239e5493572f103 320 SUPERFAMILY SSF88723 4 168 8.63E-36 T 09-03-2017 IPR029060 PIN domain-like UA74_RS13050 53afa6dde4446212b239e5493572f103 320 Gene3D G3DSA:3.40.50.1010 3 190 1.4E-44 T 09-03-2017 IPR029060 PIN domain-like UA74_RS13050 53afa6dde4446212b239e5493572f103 320 SMART SM00279 195 230 6.3E-10 T 09-03-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 UA74_RS09255 70855866c95ae1efddd70e301218f796 425 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 174 407 2.2E-81 T 09-03-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 UA74_RS09255 70855866c95ae1efddd70e301218f796 425 SUPERFAMILY SSF51735 19 115 3.15E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09255 70855866c95ae1efddd70e301218f796 425 SUPERFAMILY SSF53790 172 407 5.1E-71 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS09255 70855866c95ae1efddd70e301218f796 425 Gene3D G3DSA:3.30.950.10 288 410 3.8E-43 T 09-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS09255 70855866c95ae1efddd70e301218f796 425 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 19 140 1.6E-19 T 09-03-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 UA74_RS09255 70855866c95ae1efddd70e301218f796 425 Pfam PF13241 Putative NAD(P)-binding 19 124 2.8E-19 T 09-03-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 UA74_RS09255 70855866c95ae1efddd70e301218f796 425 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 174 385 7.6E-49 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS09255 70855866c95ae1efddd70e301218f796 425 Gene3D G3DSA:3.40.50.720 19 118 1.7E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09255 70855866c95ae1efddd70e301218f796 425 Gene3D G3DSA:3.40.1010.10 174 287 3.4E-39 T 09-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS07485 dea3b9825514d1730e96da58755bab8c 376 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 26 205 1.2E-26 T 09-03-2017 UA74_RS07485 dea3b9825514d1730e96da58755bab8c 376 Gene3D G3DSA:3.40.50.150 19 237 5.4E-52 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07485 dea3b9825514d1730e96da58755bab8c 376 SUPERFAMILY SSF53335 11 206 9.77E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 Gene3D G3DSA:1.25.40.10 75 148 1.0E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 Pfam PF13424 Tetratricopeptide repeat 649 721 4.2E-8 T 09-03-2017 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SUPERFAMILY SSF48452 729 869 3.6E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SUPERFAMILY SSF48452 649 757 3.26E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 Pfam PF03704 Bacterial transcriptional activator domain 24 167 3.3E-19 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 PRINTS PR00364 Disease resistance protein signature 229 244 4.1E-8 T 09-03-2017 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 PRINTS PR00364 Disease resistance protein signature 397 411 4.1E-8 T 09-03-2017 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 PRINTS PR00364 Disease resistance protein signature 309 323 4.1E-8 T 09-03-2017 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SMART SM00028 769 802 1.5 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SMART SM00028 689 722 110.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SMART SM00028 729 762 270.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SMART SM00028 649 682 9.6 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SMART SM00028 849 882 170.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SMART SM00028 809 842 80.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SMART SM01043 24 168 3.5E-18 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SUPERFAMILY SSF52540 189 461 4.41E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 Gene3D G3DSA:3.40.50.300 213 347 9.5E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 Pfam PF00931 NB-ARC domain 224 463 1.8E-14 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 SUPERFAMILY SSF48452 23 187 2.45E-22 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23135 39a37daafc14cf21a7114d21cbf5f63c 897 Gene3D G3DSA:1.25.40.10 616 881 6.4E-29 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SUPERFAMILY SSF48452 543 851 8.09E-45 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 Gene3D G3DSA:3.40.50.300 39 78 3.6E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 746 779 0.0012 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 780 813 1.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 610 643 0.03 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 678 711 110.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 542 575 2.2 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 814 847 1.2 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 576 609 0.074 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 712 745 0.13 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 644 677 11.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13432 Tetratricopeptide repeat 619 676 0.0083 T 09-03-2017 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13432 Tetratricopeptide repeat 752 806 2.5E-5 T 09-03-2017 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13432 Tetratricopeptide repeat 546 608 1.4E-7 T 09-03-2017 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SUPERFAMILY SSF52540 213 313 9.91E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 SUPERFAMILY SSF52540 18 103 9.91E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 Gene3D G3DSA:1.25.40.10 544 729 9.2E-45 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13191 AAA ATPase domain 20 239 3.7E-9 T 09-03-2017 UA74_RS11215 7e2b840642201d9facd3124dc20f25ee 875 Gene3D G3DSA:1.25.40.10 730 845 6.0E-24 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS20385 e8544ad21550a2ac6208eaff10327c1f 456 Gene3D G3DSA:1.10.630.10 14 396 6.3E-82 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20385 e8544ad21550a2ac6208eaff10327c1f 456 PRINTS PR00359 B-class P450 signature 143 159 8.9E-7 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20385 e8544ad21550a2ac6208eaff10327c1f 456 PRINTS PR00359 B-class P450 signature 336 345 8.9E-7 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20385 e8544ad21550a2ac6208eaff10327c1f 456 PRINTS PR00359 B-class P450 signature 195 217 8.9E-7 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20385 e8544ad21550a2ac6208eaff10327c1f 456 PRINTS PR00359 B-class P450 signature 97 108 8.9E-7 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20385 e8544ad21550a2ac6208eaff10327c1f 456 SUPERFAMILY SSF48264 9 396 3.27E-58 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 SUPERFAMILY SSF103473 12 412 9.02E-69 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 117 138 2.5E-6 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 90 114 2.5E-6 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 33 49 2.5E-6 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 290 311 2.5E-6 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 Gene3D G3DSA:1.20.1250.20 220 414 3.5E-14 T 09-03-2017 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 Gene3D G3DSA:1.20.1250.20 20 207 1.9E-30 T 09-03-2017 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 20 398 4.4E-104 T 09-03-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 UA74_RS06970 f16252cfd8cdbec9a41c49f333bd6170 432 Pfam PF07690 Major Facilitator Superfamily 30 371 3.4E-47 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.9 T 09-03-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 Gene3D G3DSA:3.40.50.450 1 211 2.1E-72 T 09-03-2017 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 09-03-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 SUPERFAMILY SSF53784 1 333 1.83E-117 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 4.0E-72 T 09-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 2.4E-151 T 09-03-2017 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 Pfam PF00365 Phosphofructokinase 2 296 9.4E-101 T 09-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_RS24945 6be2a5ce58d29be5a83f7728788939ef 341 PIRSF PIRSF000532 1 338 1.7E-119 T 09-03-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 23 263 8.5E-50 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 SUPERFAMILY SSF55120 21 275 1.18E-71 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 21 268 32.11 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 PIRSF PIRSF001430 20 285 4.4E-70 T 09-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 Gene3D G3DSA:3.30.70.660 130 266 2.3E-35 T 09-03-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 Pfam PF01416 tRNA pseudouridine synthase 167 269 1.2E-24 T 09-03-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 Pfam PF01416 tRNA pseudouridine synthase 29 126 7.1E-6 T 09-03-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03145 fe1517848119386bf87a40f948ece56e 286 Gene3D G3DSA:3.30.70.580 21 128 2.2E-33 T 09-03-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS15750 3e3ce4e7ec1244ee501c2191516ebd63 128 SUPERFAMILY SSF47413 8 68 4.3E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS15750 3e3ce4e7ec1244ee501c2191516ebd63 128 Gene3D G3DSA:1.10.260.40 7 68 1.2E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 Gene3D G3DSA:3.40.50.720 166 387 3.0E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 Pfam PF00390 Malic enzyme, N-terminal domain 33 119 1.3E-19 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 SUPERFAMILY SSF51735 168 387 2.84E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 SMART SM00919 168 388 8.7E-102 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 PIRSF PIRSF000106 33 388 5.4E-64 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 SUPERFAMILY SSF53223 18 166 3.09E-49 T 09-03-2017 UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 Gene3D G3DSA:3.40.50.10380 20 165 6.5E-48 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 SMART SM01274 23 156 7.4E-68 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_RS26590 95f6e9f5b99a3625f223e161aa63285c 388 Pfam PF03949 Malic enzyme, NAD binding domain 170 387 8.4E-18 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 SUPERFAMILY SSF142019 17 251 6.02E-87 T 09-03-2017 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 344 423 1.0E-31 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 60 231 2.4E-46 T 09-03-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 Pfam PF10531 SLBB domain 256 302 1.4E-10 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 Gene3D G3DSA:3.10.560.10 256 287 5.4E-4 T 09-03-2017 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 SMART SM00928 340 385 4.0E-24 T 09-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 SUPERFAMILY SSF140490 338 431 2.22E-34 T 09-03-2017 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 353 364 - T 09-03-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 179 194 - T 09-03-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 21 423 2.0E-186 T 09-03-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02565 9072effc459179bf43c0d8dce6f3c4bd 446 SUPERFAMILY SSF142984 253 335 3.66E-22 T 09-03-2017 UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 SUPERFAMILY SSF46785 7 112 2.16E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 Gene3D G3DSA:1.10.10.10 7 81 4.3E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 Pfam PF03466 LysR substrate binding domain 117 292 5.7E-15 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 Gene3D G3DSA:3.40.190.10 195 264 4.5E-4 T 09-03-2017 UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 7 295 6.0E-104 T 09-03-2017 IPR017685 HTH-type transcriptional regulator ArgP UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 7.6E-15 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 Gene3D G3DSA:3.40.190.10 92 194 1.4E-39 T 09-03-2017 UA74_RS20895 a54a26f4325f919a4e3a288d18bcaf26 311 SUPERFAMILY SSF53850 94 296 3.08E-20 T 09-03-2017 UA74_RS04185 5878f59038b8c3de6622867bb4d84caf 433 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 32 423 2.1E-109 T 09-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS04185 5878f59038b8c3de6622867bb4d84caf 433 Pfam PF13742 OB-fold nucleic acid binding domain 31 125 2.9E-15 T 09-03-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 UA74_RS04185 5878f59038b8c3de6622867bb4d84caf 433 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 24 424 23.128 T 09-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS04185 5878f59038b8c3de6622867bb4d84caf 433 Pfam PF02601 Exonuclease VII, large subunit 148 360 8.0E-57 T 09-03-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 UA74_RS26730 b4727ebb3f760e879020fc6b8c2a8b6b 250 SUPERFAMILY SSF53271 55 111 5.54E-13 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS26730 b4727ebb3f760e879020fc6b8c2a8b6b 250 SUPERFAMILY SSF53271 138 227 5.54E-13 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS26730 b4727ebb3f760e879020fc6b8c2a8b6b 250 Gene3D G3DSA:3.40.50.2020 64 223 4.8E-17 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS19450 6621d73195a2603ac6b06b84cad4b527 827 Pfam PF13560 Helix-turn-helix domain 4 66 1.3E-16 T 09-03-2017 UA74_RS19450 6621d73195a2603ac6b06b84cad4b527 827 Gene3D G3DSA:1.10.260.40 3 60 3.2E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS19450 6621d73195a2603ac6b06b84cad4b527 827 Pfam PF05729 NACHT domain 226 379 2.4E-7 T 09-03-2017 UA74_RS19450 6621d73195a2603ac6b06b84cad4b527 827 SMART SM00530 8 64 8.1E-15 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS19450 6621d73195a2603ac6b06b84cad4b527 827 SUPERFAMILY SSF52540 191 385 8.62E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19450 6621d73195a2603ac6b06b84cad4b527 827 SUPERFAMILY SSF47413 3 60 3.38E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 SUPERFAMILY SSF51735 117 295 5.09E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 SMART SM00829 11 328 3.6E-40 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Gene3D G3DSA:3.40.50.720 148 239 4.6E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 09-03-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Gene3D G3DSA:3.90.180.10 1 147 1.9E-42 T 09-03-2017 IPR011032 GroES-like UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 SUPERFAMILY SSF50129 1 147 6.7E-37 T 09-03-2017 IPR011032 GroES-like UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 87 1.9E-10 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS05355 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Pfam PF13602 Zinc-binding dehydrogenase 185 328 3.9E-35 T 09-03-2017 UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 Gene3D G3DSA:1.10.1740.10 2 81 2.5E-15 T 09-03-2017 UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 168 1.2E-44 T 09-03-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 SUPERFAMILY SSF88659 109 166 5.61E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 Pfam PF04542 Sigma-70 region 2 18 79 7.2E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 SUPERFAMILY SSF88946 3 97 6.28E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 Gene3D G3DSA:1.10.10.10 110 167 7.8E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 164 6.9E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29475 351267061e6db3c7a45d514694b6e515 182 Pfam PF08281 Sigma-70, region 4 111 161 1.8E-15 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 964 978 - T 09-03-2017 IPR019775 WD40 repeat, conserved site UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:2.130.10.10 632 788 1.3E-34 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SUPERFAMILY SSF50998 623 942 9.42E-62 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SUPERFAMILY SSF52540 78 304 3.68E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1180 1212 1.3E-7 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 679 710 4.5E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 815 847 4.3E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1141 1166 4.8E-6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1099 1122 0.024 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 905 939 5.6E-4 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 776 801 3.5E-4 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1226 1265 0.0098 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 945 977 0.0014 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 671 710 1.2E-6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1037 1073 3.7 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 808 847 2.4E-6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 983 1031 50.0 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 857 893 0.73 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 625 664 6.3E-4 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 763 801 0.0031 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 941 977 0.45 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 900 939 1.3E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 717 756 1.8 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1219 1266 0.06 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1170 1212 7.7E-9 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1123 1166 1.2E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1083 1122 0.32 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:3.40.50.300 76 121 8.6E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 926 940 - T 09-03-2017 IPR019775 WD40 repeat, conserved site UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:2.130.10.10 1063 1268 6.4E-45 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:2.130.10.10 789 1062 1.9E-64 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 788 802 - T 09-03-2017 IPR019775 WD40 repeat, conserved site UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 PRINTS PR00320 G protein beta WD-40 repeat signature 788 802 9.3E-7 T 09-03-2017 IPR020472 G-protein beta WD-40 repeat UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 PRINTS PR00320 G protein beta WD-40 repeat signature 1153 1167 9.3E-7 T 09-03-2017 IPR020472 G-protein beta WD-40 repeat UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 PRINTS PR00320 G protein beta WD-40 repeat signature 697 711 9.3E-7 T 09-03-2017 IPR020472 G-protein beta WD-40 repeat UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 697 711 - T 09-03-2017 IPR019775 WD40 repeat, conserved site UA74_RS18420 a6bb8db14e136d443f16aef6f1529ae6 1304 SUPERFAMILY SSF50978 945 1267 1.34E-53 T 09-03-2017 IPR017986 WD40-repeat-containing domain GO:0005515 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF47336 5328 5409 8.51E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00698 Acyl transferase domain 91 409 1.1E-79 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00698 Acyl transferase domain 2581 2897 5.9E-80 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00698 Acyl transferase domain 1107 1411 3.2E-53 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00698 Acyl transferase domain 4254 4565 5.2E-83 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM01294 462 525 3.6E-5 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM01294 5335 5402 3.2E-5 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM01294 1955 2022 1.1E-4 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM01294 3632 3699 1.4E-5 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF14765 Polyketide synthase dehydratase 4612 4881 9.5E-54 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF14765 Polyketide synthase dehydratase 2943 3213 4.8E-55 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4103 4213 1.6E-13 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2422 2541 3.4E-13 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 922 1070 5.1E-10 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF51735 3220 3350 3.74E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5361 5376 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1981 1996 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF51735 5062 5305 1.55E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF51735 1681 1901 1.89E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF55048 2702 2764 4.05E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00825 Beta-ketoacyl synthase 549 971 7.1E-204 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00825 Beta-ketoacyl synthase 2048 2472 7.2E-216 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00825 Beta-ketoacyl synthase 3729 4153 8.9E-225 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3890 3906 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 484 499 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00550 Phosphopantetheine attachment site 1958 2022 5.4E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00550 Phosphopantetheine attachment site 460 525 3.9E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00550 Phosphopantetheine attachment site 5338 5401 3.7E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00550 Phosphopantetheine attachment site 3633 3699 2.4E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF51735 1499 1674 4.72E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.47.10 809 971 9.3E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.47.10 3990 4153 3.5E-68 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.47.10 2309 2472 9.7E-66 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00826 2943 3105 3.8E-75 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00826 4612 4773 1.2E-75 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.47.10 549 808 4.0E-87 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.47.10 2048 2308 3.5E-91 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.47.10 3729 3989 4.4E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 804 919 5.2E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2304 2419 3.1E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3985 4100 2.5E-45 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 4437 4546 1.2E-66 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 2764 2878 2.0E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 2579 2698 2.0E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 4252 4371 1.2E-66 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 709 725 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4255 4546 7.1E-110 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2582 2878 3.8E-109 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 92 390 1.1E-92 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1107 1394 6.3E-118 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF53901 3725 4097 4.95E-103 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5064 5238 1.3E-51 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3362 3536 3.1E-51 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1685 1860 6.9E-52 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF47336 452 562 2.62E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 4438 4535 2.38E-62 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 4252 4377 2.38E-62 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3658 3673 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF53901 2043 2416 4.64E-103 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.50.720 5064 5257 7.0E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.30.70.250 1229 1283 7.3E-7 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.30.70.250 215 279 2.9E-4 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.30.70.250 4376 4436 6.8E-7 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.30.70.250 2704 2763 3.0E-6 T 09-03-2017 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 1280 1394 8.63E-73 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 1104 1225 8.63E-73 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 89 217 2.62E-60 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 281 378 2.62E-60 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF55048 1230 1286 2.62E-9 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:1.10.1200.10 1953 2025 2.0E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:1.10.1200.10 456 529 5.8E-19 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:1.10.1200.10 3630 3703 4.1E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:1.10.1200.10 5332 5404 2.0E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF08659 KR domain 5064 5236 3.3E-53 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF08659 KR domain 1685 1858 1.3E-57 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF08659 KR domain 3362 3534 1.9E-54 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF51735 3360 3606 3.1E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF47336 1951 2061 2.49E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 2765 2860 1.12E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF52151 2579 2704 1.12E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.50.720 3361 3564 4.8E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.50.720 1685 1886 6.7E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF53901 543 916 1.22E-101 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 1097 1225 1.1E-78 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 280 393 2.2E-64 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 88 211 2.2E-64 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Gene3D G3DSA:3.40.366.10 1286 1393 1.1E-78 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2209 2225 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF55048 215 279 1.44E-9 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3727 3977 1.7E-90 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2046 2296 1.4E-91 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 547 796 2.4E-81 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF47336 3628 3742 1.57E-24 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF51735 4888 5050 2.44E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SUPERFAMILY SSF55048 4375 4437 3.27E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00823 Phosphopantetheine attachment site 1954 2026 2.7E-29 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00823 Phosphopantetheine attachment site 5334 5406 4.8E-28 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00823 Phosphopantetheine attachment site 457 529 7.8E-30 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17360 099abe14290ccb16d355c4489475b1cb 5485 SMART SM00823 Phosphopantetheine attachment site 3631 3703 5.1E-32 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS15030 26a47b87c3607edd98fd3cb02a9196cf 113 SUPERFAMILY SSF46955 1 112 2.16E-23 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS15030 26a47b87c3607edd98fd3cb02a9196cf 113 SMART SM00422 1 69 6.7E-17 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15030 26a47b87c3607edd98fd3cb02a9196cf 113 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.6E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15030 26a47b87c3607edd98fd3cb02a9196cf 113 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.6E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15030 26a47b87c3607edd98fd3cb02a9196cf 113 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.6E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15030 26a47b87c3607edd98fd3cb02a9196cf 113 Pfam PF13411 MerR HTH family regulatory protein 1 66 4.2E-18 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15030 26a47b87c3607edd98fd3cb02a9196cf 113 Gene3D G3DSA:1.10.1660.10 1 112 2.0E-27 T 09-03-2017 UA74_RS15860 80a8e767b873be9aee53f5a2fa278224 350 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 175 203 - T 09-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UA74_RS15860 80a8e767b873be9aee53f5a2fa278224 350 Gene3D G3DSA:2.160.10.10 98 224 5.4E-32 T 09-03-2017 UA74_RS15860 80a8e767b873be9aee53f5a2fa278224 350 SUPERFAMILY SSF51161 8 73 4.71E-6 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS15860 80a8e767b873be9aee53f5a2fa278224 350 SUPERFAMILY SSF51161 59 220 8.92E-31 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS15860 80a8e767b873be9aee53f5a2fa278224 350 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 167 200 1.2E-5 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS15860 80a8e767b873be9aee53f5a2fa278224 350 Gene3D G3DSA:2.160.10.10 7 97 8.0E-10 T 09-03-2017 UA74_RS11295 7c4e10b6efd3787dfa04f671cc52a7fe 59 Pfam PF04149 Domain of unknown function (DUF397) 6 55 2.9E-20 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 Pfam PF00694 Aconitase C-terminal domain 733 866 2.4E-41 T 09-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 SUPERFAMILY SSF53732 8 408 6.8E-218 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 SUPERFAMILY SSF53732 442 668 6.8E-218 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 Pfam PF00330 Aconitase family (aconitate hydratase) 75 603 1.2E-176 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:3.30.499.10 32 251 1.7E-77 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 SUPERFAMILY SSF52016 672 941 2.75E-82 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:3.30.499.10 371 395 3.0E-66 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:3.30.499.10 460 616 3.0E-66 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:3.20.19.10 678 940 3.0E-76 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 ProSitePatterns PS00450 Aconitase family signature 1. 468 484 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 205 218 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 145 158 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 219 234 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 472 483 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 295 308 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 169 177 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 374 388 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 281 294 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 534 547 1.8E-42 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 31 941 0.0 T 09-03-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 ProSitePatterns PS01244 Aconitase family signature 2. 534 547 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_RS11550 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:3.40.1060.10 252 369 4.4E-34 T 09-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS14630 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 335 1.3E-75 T 09-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 UA74_RS14630 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 Gene3D G3DSA:3.40.50.1970 5 156 5.1E-36 T 09-03-2017 UA74_RS14630 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 SUPERFAMILY SSF56796 7 349 2.22E-86 T 09-03-2017 UA74_RS14630 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 Gene3D G3DSA:1.20.1090.10 159 345 1.0E-40 T 09-03-2017 UA74_RS26710 75b4f18161e562f35582b7f4057a8d25 141 Gene3D G3DSA:3.40.50.1000 26 130 2.5E-28 T 09-03-2017 IPR023214 HAD-like domain UA74_RS26710 75b4f18161e562f35582b7f4057a8d25 141 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 37 107 9.3E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS26710 75b4f18161e562f35582b7f4057a8d25 141 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 18 116 7.4E-17 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS26710 75b4f18161e562f35582b7f4057a8d25 141 Pfam PF13419 Haloacid dehalogenase-like hydrolase 56 112 1.9E-8 T 09-03-2017 IPR023214 HAD-like domain UA74_RS26710 75b4f18161e562f35582b7f4057a8d25 141 SUPERFAMILY SSF56784 6 126 1.36E-23 T 09-03-2017 IPR023214 HAD-like domain UA74_RS22740 035138002ce5d2840012190b50be413f 340 SUPERFAMILY SSF52540 20 268 1.01E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22740 035138002ce5d2840012190b50be413f 340 SMART SM00382 48 247 1.3E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22740 035138002ce5d2840012190b50be413f 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 333 4.4E-27 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS22740 035138002ce5d2840012190b50be413f 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 313 8.3E-19 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS22740 035138002ce5d2840012190b50be413f 340 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS22740 035138002ce5d2840012190b50be413f 340 Gene3D G3DSA:3.40.50.300 19 271 1.5E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22740 035138002ce5d2840012190b50be413f 340 Pfam PF00005 ABC transporter 40 197 1.1E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS11450 b45d1ccdb4e56a26744857dd5ec7ba6c 200 Pfam PF01066 CDP-alcohol phosphatidyltransferase 13 77 1.3E-15 T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_RS11450 b45d1ccdb4e56a26744857dd5ec7ba6c 200 PIRSF PIRSF000847 8 194 1.6E-43 T 09-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 UA74_RS11450 b45d1ccdb4e56a26744857dd5ec7ba6c 200 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 55 77 - T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_RS26690 d1470b424567894af2f5de15808f5e47 542 Gene3D G3DSA:3.40.309.10 308 505 2.7E-43 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS26690 d1470b424567894af2f5de15808f5e47 542 Pfam PF00171 Aldehyde dehydrogenase family 56 521 1.2E-99 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS26690 d1470b424567894af2f5de15808f5e47 542 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 UA74_RS26690 d1470b424567894af2f5de15808f5e47 542 Gene3D G3DSA:3.40.605.10 45 307 4.4E-63 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS26690 d1470b424567894af2f5de15808f5e47 542 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 292 299 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS26690 d1470b424567894af2f5de15808f5e47 542 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 541 4.0E-238 T 09-03-2017 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-70688 UA74_RS26690 d1470b424567894af2f5de15808f5e47 542 SUPERFAMILY SSF53720 9 527 8.51E-119 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 Pfam PF00107 Zinc-binding dehydrogenase 181 301 5.3E-15 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 SMART SM00829 10 338 3.1E-9 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 Gene3D G3DSA:3.40.50.720 175 273 7.1E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 SUPERFAMILY SSF51735 144 308 1.65E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 SUPERFAMILY SSF50129 1 163 4.26E-44 T 09-03-2017 IPR011032 GroES-like UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 Gene3D G3DSA:3.90.180.10 1 174 3.7E-50 T 09-03-2017 IPR011032 GroES-like UA74_RS17675 de843cc3a14285f28464fc4a3756e34e 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 6.3E-22 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS28125 7581c5cd6be9a4aa6d12efb24188e61a 184 SUPERFAMILY SSF55729 1 157 4.18E-29 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS28125 7581c5cd6be9a4aa6d12efb24188e61a 184 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 12 155 1.3E-32 T 09-03-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 UA74_RS28125 7581c5cd6be9a4aa6d12efb24188e61a 184 Gene3D G3DSA:3.40.630.30 1 158 5.4E-32 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS28125 7581c5cd6be9a4aa6d12efb24188e61a 184 Pfam PF00583 Acetyltransferase (GNAT) family 63 136 2.9E-15 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS03760 33909874899108ac0ffbea3207202ad7 319 SUPERFAMILY SSF53067 3 127 5.61E-35 T 09-03-2017 UA74_RS03760 33909874899108ac0ffbea3207202ad7 319 Pfam PF02541 Ppx/GppA phosphatase family 26 314 8.9E-72 T 09-03-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 UA74_RS03760 33909874899108ac0ffbea3207202ad7 319 Gene3D G3DSA:3.30.420.150 131 317 1.9E-57 T 09-03-2017 UA74_RS03760 33909874899108ac0ffbea3207202ad7 319 Gene3D G3DSA:3.30.420.40 1 128 7.5E-50 T 09-03-2017 UA74_RS03760 33909874899108ac0ffbea3207202ad7 319 SUPERFAMILY SSF53067 133 317 5.5E-35 T 09-03-2017 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.30.70.250 691 755 2.0E-12 T 09-03-2017 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF08659 KR domain 1236 1415 2.7E-31 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 298 411 4.0E-32 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00826 1478 1640 8.5E-4 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1234 1417 2.2E-17 T 09-03-2017 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF51735 1234 1476 4.77E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.47.10 303 465 9.2E-44 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF00698 Acyl transferase domain 620 841 1.2E-24 T 09-03-2017 IPR014043 Acyl transferase UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 290 1.9E-52 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF47336 949 1028 7.81E-5 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.50.720 1235 1419 1.6E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF54637 1481 1558 9.51E-7 T 09-03-2017 IPR029069 HotDog domain UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF55048 693 756 6.28E-11 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF53901 3 123 1.81E-58 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF53901 187 411 1.81E-58 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF52151 582 693 3.92E-43 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF52151 757 856 3.92E-43 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.47.10 6 127 4.0E-58 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.47.10 160 302 4.0E-58 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.366.10 577 687 8.6E-38 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.366.10 756 855 8.6E-38 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF14765 Polyketide synthase dehydratase 1487 1759 4.7E-43 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 424 540 6.1E-8 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.10.129.10 1478 1587 3.5E-6 T 09-03-2017 IPR029069 HotDog domain UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00825 Beta-ketoacyl synthase 6 466 1.4E-60 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS18675 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 586 882 2.1E-38 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS27910 fde8a1b0844bdd8e24e6af02afcd3ce5 421 SUPERFAMILY SSF47413 11 64 3.66E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS27910 fde8a1b0844bdd8e24e6af02afcd3ce5 421 SMART SM00530 13 68 3.1E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS27910 fde8a1b0844bdd8e24e6af02afcd3ce5 421 Pfam PF13560 Helix-turn-helix domain 10 69 1.1E-10 T 09-03-2017 UA74_RS27910 fde8a1b0844bdd8e24e6af02afcd3ce5 421 Gene3D G3DSA:1.10.260.40 10 63 4.2E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS27910 fde8a1b0844bdd8e24e6af02afcd3ce5 421 Gene3D G3DSA:1.25.40.10 193 379 7.1E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS15170 df559ddff29b087fc066d21514a657f9 267 SUPERFAMILY SSF51735 2 224 2.67E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15170 df559ddff29b087fc066d21514a657f9 267 Pfam PF13460 NAD(P)H-binding 7 168 1.0E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15170 df559ddff29b087fc066d21514a657f9 267 Gene3D G3DSA:3.40.50.720 1 202 4.6E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14115 a5aadaa8d766e248c576e23d334e898d 131 Gene3D G3DSA:3.40.630.30 12 124 7.1E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14115 a5aadaa8d766e248c576e23d334e898d 131 Pfam PF00583 Acetyltransferase (GNAT) family 47 122 1.8E-9 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS14115 a5aadaa8d766e248c576e23d334e898d 131 SUPERFAMILY SSF55729 13 125 1.18E-15 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS21580 34593a82639a393b7a1055301fabd919 570 Hamap MF_01227 CTP synthase [pyrG]. 8 549 49.926 T 09-03-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UA74_RS21580 34593a82639a393b7a1055301fabd919 570 SUPERFAMILY SSF52540 9 277 2.66E-117 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21580 34593a82639a393b7a1055301fabd919 570 TIGRFAM TIGR00337 PyrG: CTP synthase 7 544 1.3E-225 T 09-03-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UA74_RS21580 34593a82639a393b7a1055301fabd919 570 SUPERFAMILY SSF52317 300 550 6.48E-74 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS21580 34593a82639a393b7a1055301fabd919 570 Gene3D G3DSA:3.40.50.880 299 550 1.6E-89 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS21580 34593a82639a393b7a1055301fabd919 570 Pfam PF00117 Glutamine amidotransferase class-I 312 543 1.2E-48 T 09-03-2017 IPR017926 Glutamine amidotransferase UA74_RS21580 34593a82639a393b7a1055301fabd919 570 Pfam PF06418 CTP synthase N-terminus 9 277 3.6E-121 T 09-03-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UA74_RS21580 34593a82639a393b7a1055301fabd919 570 Gene3D G3DSA:3.40.50.300 5 295 9.1E-129 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11620 9b8529d1c5fece2dd01069016ab5c5e3 357 Gene3D G3DSA:3.40.50.1400 155 293 8.6E-48 T 09-03-2017 UA74_RS11620 9b8529d1c5fece2dd01069016ab5c5e3 357 TIGRFAM TIGR00109 hemH: ferrochelatase 5 311 6.7E-43 T 09-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UA74_RS11620 9b8529d1c5fece2dd01069016ab5c5e3 357 Hamap MF_00323 Ferrochelatase [hemH]. 2 313 31.629 T 09-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UA74_RS11620 9b8529d1c5fece2dd01069016ab5c5e3 357 Gene3D G3DSA:3.40.50.1400 4 154 9.6E-39 T 09-03-2017 UA74_RS11620 9b8529d1c5fece2dd01069016ab5c5e3 357 SUPERFAMILY SSF53800 3 323 2.62E-84 T 09-03-2017 UA74_RS11620 9b8529d1c5fece2dd01069016ab5c5e3 357 Pfam PF00762 Ferrochelatase 4 311 7.4E-96 T 09-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UA74_RS18770 b0a5ac571aae9a436045a8cfc098a224 269 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 257 36.857 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS18770 b0a5ac571aae9a436045a8cfc098a224 269 Gene3D G3DSA:3.40.1180.10 23 257 3.4E-83 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS18770 b0a5ac571aae9a436045a8cfc098a224 269 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 09-03-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 UA74_RS18770 b0a5ac571aae9a436045a8cfc098a224 269 SUPERFAMILY SSF64005 27 252 2.49E-73 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS18770 b0a5ac571aae9a436045a8cfc098a224 269 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 256 3.8E-68 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS18770 b0a5ac571aae9a436045a8cfc098a224 269 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 256 3.5E-72 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS12525 225fa36be73ff906cd8fdd433e261ed0 190 Pfam PF10400 Virulence activator alpha C-term 92 179 1.4E-15 T 09-03-2017 IPR018309 Transcription regulator PadR, C-terminal UA74_RS12525 225fa36be73ff906cd8fdd433e261ed0 190 Gene3D G3DSA:1.10.10.10 1 86 2.2E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12525 225fa36be73ff906cd8fdd433e261ed0 190 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 2.1E-5 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS12525 225fa36be73ff906cd8fdd433e261ed0 190 SUPERFAMILY SSF46785 3 179 1.88E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28645 b764905e41cd34f7e73db7c94de677a7 346 Pfam PF09084 NMT1/THI5 like 73 279 1.9E-28 T 09-03-2017 IPR015168 SsuA/THI5-like UA74_RS28645 b764905e41cd34f7e73db7c94de677a7 346 SUPERFAMILY SSF53850 59 283 9.93E-41 T 09-03-2017 UA74_RS28645 b764905e41cd34f7e73db7c94de677a7 346 SMART SM00062 74 296 0.002 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS28645 b764905e41cd34f7e73db7c94de677a7 346 Gene3D G3DSA:3.40.190.10 159 270 6.5E-24 T 09-03-2017 UA74_RS28645 b764905e41cd34f7e73db7c94de677a7 346 Gene3D G3DSA:3.40.190.10 83 158 3.5E-4 T 09-03-2017 UA74_RS09050 8e27f2f8ce1c4b8c74b21512b30e96bc 194 SUPERFAMILY SSF55194 12 193 4.84E-67 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 UA74_RS09050 8e27f2f8ce1c4b8c74b21512b30e96bc 194 TIGRFAM TIGR00496 frr: ribosome recycling factor 19 194 1.2E-63 T 09-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 UA74_RS09050 8e27f2f8ce1c4b8c74b21512b30e96bc 194 Pfam PF01765 Ribosome recycling factor 30 192 8.1E-59 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 UA74_RS09050 8e27f2f8ce1c4b8c74b21512b30e96bc 194 Hamap MF_00040 Ribosome-recycling factor [frr]. 12 194 26.428 T 09-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 UA74_RS09050 8e27f2f8ce1c4b8c74b21512b30e96bc 194 Gene3D G3DSA:1.10.132.20 75 194 1.2E-39 T 09-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 SUPERFAMILY SSF46785 5 59 4.89E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 Pfam PF00455 DeoR C terminal sensor domain 76 234 1.1E-47 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 SUPERFAMILY SSF100950 75 236 2.22E-34 T 09-03-2017 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 Gene3D G3DSA:3.40.50.1360 75 216 2.2E-16 T 09-03-2017 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 8.1E-17 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 Gene3D G3DSA:1.10.10.10 4 55 8.0E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.8E-8 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.8E-8 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 SMART SM00420 6 58 3.5E-18 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS18395 68e424a6f79dde3e3774d6e305791b8d 267 SMART SM01134 74 236 2.8E-60 T 09-03-2017 UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 384 5.1E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 SUPERFAMILY SSF55874 264 385 2.62E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 SMART SM00387 297 386 5.1E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 SUPERFAMILY SSF55781 25 181 2.18E-17 T 09-03-2017 IPR029016 GAF domain-like UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 Gene3D G3DSA:3.30.565.10 281 385 3.8E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 Pfam PF07730 Histidine kinase 188 254 1.2E-13 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 Pfam PF13185 GAF domain 25 171 2.1E-12 T 09-03-2017 IPR003018 GAF domain GO:0005515 UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 Gene3D G3DSA:3.30.450.40 8 181 6.7E-22 T 09-03-2017 IPR029016 GAF domain-like UA74_RS00555 5f3d3be51ba7ba9fd334fe20b914573c 386 SMART SM00065 25 181 1.1E-6 T 09-03-2017 IPR003018 GAF domain GO:0005515 UA74_RS27640 ba72f56c8e665535f75ab0b65e04bd32 362 Hamap MF_00540 Adenosine deaminase [add]. 8 353 52.324 T 09-03-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 UA74_RS27640 ba72f56c8e665535f75ab0b65e04bd32 362 Gene3D G3DSA:3.20.20.140 10 352 1.3E-98 T 09-03-2017 UA74_RS27640 ba72f56c8e665535f75ab0b65e04bd32 362 Pfam PF00962 Adenosine/AMP deaminase 13 350 1.9E-87 T 09-03-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 UA74_RS27640 ba72f56c8e665535f75ab0b65e04bd32 362 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 351 1.7E-74 T 09-03-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 UA74_RS27640 ba72f56c8e665535f75ab0b65e04bd32 362 SUPERFAMILY SSF51556 6 352 6.43E-70 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 PIRSF PIRSF006487 20 358 1.7E-22 T 09-03-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 Gene3D G3DSA:2.40.30.110 280 348 1.5E-4 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 SUPERFAMILY SSF103025 23 277 4.4E-57 T 09-03-2017 UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 Gene3D G3DSA:3.30.1360.120 23 50 2.7E-9 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 Gene3D G3DSA:3.30.1360.120 149 230 2.7E-9 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 223 287 2.7E-17 T 09-03-2017 IPR017703 YgfZ/GcvT conserved site UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 261 349 5.4E-8 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 Pfam PF01571 Aminomethyltransferase folate-binding domain 23 251 1.6E-29 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal UA74_RS29340 bb36bc189bd1cc3b72a3ff3c4415ae50 374 Gene3D G3DSA:3.30.70.1400 51 112 5.9E-7 T 09-03-2017 UA74_RS09505 9c1d98791cb0db8dcab09461f3137bd8 198 Gene3D G3DSA:3.40.630.30 4 176 2.1E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09505 9c1d98791cb0db8dcab09461f3137bd8 198 SUPERFAMILY SSF55729 5 163 8.29E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29335 8836d68ce467b6dc033614a00b0b60dd 283 Gene3D G3DSA:3.20.10.10 130 278 7.3E-33 T 09-03-2017 UA74_RS29335 8836d68ce467b6dc033614a00b0b60dd 283 SUPERFAMILY SSF56752 5 278 1.31E-56 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 UA74_RS29335 8836d68ce467b6dc033614a00b0b60dd 283 Pfam PF01063 Amino-transferase class IV 31 254 6.7E-44 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 UA74_RS29335 8836d68ce467b6dc033614a00b0b60dd 283 Gene3D G3DSA:3.30.470.10 5 101 8.9E-24 T 09-03-2017 UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 SUPERFAMILY SSF46785 4 83 7.72E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 Gene3D G3DSA:3.40.1410.10 75 247 1.6E-33 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 SMART SM00345 15 74 2.1E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 Pfam PF07702 UTRA domain 114 242 5.4E-18 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 SUPERFAMILY SSF64288 62 250 9.58E-26 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.5E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 Gene3D G3DSA:1.10.10.10 4 74 3.6E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26845 15648ad4f20da42a73d95e4bca3ed2c0 253 SMART SM00866 104 244 4.6E-12 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS24525 a24075f9a5a6beb401a44e93cfa0f2ae 313 Pfam PF03773 Predicted permease 30 306 1.2E-49 T 09-03-2017 IPR005524 Predicted permease DUF318 UA74_RS02495 c92ad52381f5a5ba12840f09b9bb293c 326 SUPERFAMILY SSF47240 36 279 3.24E-77 T 09-03-2017 IPR009078 Ferritin-like superfamily UA74_RS02495 c92ad52381f5a5ba12840f09b9bb293c 326 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 16 304 1.2E-147 T 09-03-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 UA74_RS02495 c92ad52381f5a5ba12840f09b9bb293c 326 Gene3D G3DSA:1.20.1260.10 26 280 1.2E-98 T 09-03-2017 IPR012347 Ferritin-related UA74_RS02495 c92ad52381f5a5ba12840f09b9bb293c 326 Pfam PF05138 Phenylacetic acid catabolic protein 26 300 1.3E-96 T 09-03-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UA74_RS12030 6b576c61abccafc18d3f1eda61fdcbac 376 SMART SM00382 27 199 1.3E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12030 6b576c61abccafc18d3f1eda61fdcbac 376 Pfam PF00005 ABC transporter 20 150 8.3E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS12030 6b576c61abccafc18d3f1eda61fdcbac 376 Gene3D G3DSA:3.40.50.300 2 181 8.8E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12030 6b576c61abccafc18d3f1eda61fdcbac 376 SUPERFAMILY SSF52540 3 182 9.45E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 SUPERFAMILY SSF52540 482 685 2.32E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 Gene3D G3DSA:3.40.50.300 1039 1236 3.2E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 Pfam PF00005 ABC transporter 503 651 3.0E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 Pfam PF00005 ABC transporter 1052 1186 1.2E-20 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 Pfam PF00664 ABC transporter transmembrane region 174 328 9.0E-9 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 Gene3D G3DSA:1.20.1560.10 715 997 2.8E-16 T 09-03-2017 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 Gene3D G3DSA:1.20.1560.10 39 366 6.6E-32 T 09-03-2017 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 SUPERFAMILY SSF90123 715 999 2.09E-24 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 SUPERFAMILY SSF90123 39 364 4.71E-34 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 SMART SM00382 1061 1232 1.3E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 SMART SM00382 516 723 2.3E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 SUPERFAMILY SSF52540 1029 1239 1.56E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 714 1215 2.2E-124 T 09-03-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 UA74_RS00550 75cc10509739cc8ce32c266f52502900 1270 Gene3D G3DSA:3.40.50.300 486 685 2.2E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 Gene3D G3DSA:3.40.50.300 288 421 2.2E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 25 771 0.0 T 09-03-2017 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 SUPERFAMILY SSF52540 72 231 3.2E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 SUPERFAMILY SSF52540 263 410 3.2E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 SMART SM00490 318 399 1.4E-13 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 Pfam PF00271 Helicase conserved C-terminal domain 291 399 1.5E-10 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 SMART SM00487 57 259 4.7E-27 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 Pfam PF00270 DEAD/DEAH box helicase 64 229 2.4E-20 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 Pfam PF09369 Domain of unknown function (DUF1998) 666 745 1.4E-16 T 09-03-2017 IPR018973 DEAD/DEAH-box helicase, putative UA74_RS01395 42b9187d28d3be65ea1118b487af7151 780 Gene3D G3DSA:3.40.50.300 40 234 5.3E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29395 f506f36517b80017bed22a891a68d046 504 Gene3D G3DSA:3.60.20.10 10 259 1.9E-60 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS29395 f506f36517b80017bed22a891a68d046 504 SUPERFAMILY SSF56235 10 270 8.23E-62 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS29395 f506f36517b80017bed22a891a68d046 504 Pfam PF00156 Phosphoribosyl transferase domain 281 388 9.2E-7 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_RS29395 f506f36517b80017bed22a891a68d046 504 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 9 460 45.866 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UA74_RS29395 f506f36517b80017bed22a891a68d046 504 SUPERFAMILY SSF53271 253 467 5.9E-68 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS29395 f506f36517b80017bed22a891a68d046 504 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 10 459 8.4E-155 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UA74_RS29395 f506f36517b80017bed22a891a68d046 504 PIRSF PIRSF000485 6 471 7.1E-156 T 09-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UA74_RS29395 f506f36517b80017bed22a891a68d046 504 Pfam PF13522 Glutamine amidotransferase domain 67 212 2.1E-11 T 09-03-2017 UA74_RS29395 f506f36517b80017bed22a891a68d046 504 Gene3D G3DSA:3.40.50.2020 275 440 7.5E-44 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 SUPERFAMILY SSF63418 2 80 3.27E-18 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 SUPERFAMILY SSF53623 127 338 7.98E-51 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 SUPERFAMILY SSF53244 345 487 1.23E-31 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 Gene3D G3DSA:3.40.1190.10 108 338 1.1E-65 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 487 1.4E-117 T 09-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 Pfam PF08245 Mur ligase middle domain 132 322 4.0E-40 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 Pfam PF01225 Mur ligase family, catalytic domain 30 74 6.1E-8 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 489 30.771 T 09-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 Gene3D G3DSA:3.90.190.20 343 491 6.9E-40 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 Gene3D G3DSA:3.40.1390.10 3 78 3.0E-23 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_RS09705 b9b5179064ef290c404dc4befd3e4270 500 Pfam PF02875 Mur ligase family, glutamate ligase domain 345 432 3.9E-20 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS21540 01693be96fe2ea8fdd7a124e9ddcc4f1 198 Pfam PF05154 TM2 domain 134 182 4.8E-9 T 09-03-2017 IPR007829 TM2 domain UA74_RS21540 01693be96fe2ea8fdd7a124e9ddcc4f1 198 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 1.9E-20 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 500 35.336 T 09-03-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 SMART SM00845 352 499 7.8E-54 T 09-03-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 Pfam PF02637 GatB domain 354 496 7.0E-39 T 09-03-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 SUPERFAMILY SSF55931 19 321 1.37E-111 T 09-03-2017 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 Pfam PF02934 GatB/GatE catalytic domain 20 314 1.3E-105 T 09-03-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 17 495 1.4E-142 T 09-03-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 SUPERFAMILY SSF89095 353 496 3.66E-25 T 09-03-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 UA74_RS26220 258a22cd89d3afd917483da93179923c 503 Gene3D G3DSA:1.10.10.410 442 496 8.0E-5 T 09-03-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal UA74_RS26220 258a22cd89d3afd917483da93179923c 503 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 165 179 - T 09-03-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 4.8E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 4.8E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 4.8E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.8E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 4.8E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 206 6.6E-4 T 09-03-2017 UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 2.2E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 2.2E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 2.2E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 Pfam PF00106 short chain dehydrogenase 7 188 5.8E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 SUPERFAMILY SSF51735 6 215 3.5E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30105 043af488de98637d7a3e5608e7aa4108 228 Gene3D G3DSA:3.40.50.720 6 215 2.4E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 Pfam PF02803 Thiolase, C-terminal domain 270 391 8.5E-39 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 Gene3D G3DSA:3.40.47.10 276 391 1.9E-51 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 Gene3D G3DSA:3.40.47.10 149 187 1.9E-51 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 8.4E-130 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 SUPERFAMILY SSF53901 270 391 2.14E-39 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 Gene3D G3DSA:3.40.47.10 4 126 1.1E-60 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 Gene3D G3DSA:3.40.47.10 188 275 1.1E-60 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 PIRSF PIRSF000429 1 392 6.8E-114 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 Pfam PF00108 Thiolase, N-terminal domain 5 262 2.0E-60 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 UA74_RS11775 1102272a6ddebe356474204fa79e21f3 392 SUPERFAMILY SSF53901 1 266 1.45E-67 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 SUPERFAMILY SSF53901 415 632 1.4E-29 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 227 341 2.2E-34 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 SUPERFAMILY SSF53901 599 738 9.88E-18 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 6 232 1.9E-42 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 SMART SM00825 Beta-ketoacyl synthase 6 405 4.6E-15 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 SUPERFAMILY SSF53901 4 339 1.47E-57 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 236 402 2.7E-50 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 648 772 1.6E-9 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 464 623 1.2E-12 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 217 1.6E-34 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS05815 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 444 638 1.3E-24 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS19025 99be310c6aebed77a396b0a9fefa9e96 120 SMART SM00418 2 84 2.3E-20 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19025 99be310c6aebed77a396b0a9fefa9e96 120 Gene3D G3DSA:1.10.10.10 3 106 8.6E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19025 99be310c6aebed77a396b0a9fefa9e96 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 3.6E-10 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19025 99be310c6aebed77a396b0a9fefa9e96 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 3.6E-10 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19025 99be310c6aebed77a396b0a9fefa9e96 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 3.6E-10 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19025 99be310c6aebed77a396b0a9fefa9e96 120 SUPERFAMILY SSF46785 3 101 3.91E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19025 99be310c6aebed77a396b0a9fefa9e96 120 Pfam PF12840 Helix-turn-helix domain 4 63 5.1E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16770 21cb05204d62663489f32d03150232aa 262 Pfam PF00106 short chain dehydrogenase 2 183 1.6E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 SUPERFAMILY SSF51735 2 243 1.55E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16770 21cb05204d62663489f32d03150232aa 262 Gene3D G3DSA:3.40.50.720 2 214 4.2E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 3.4E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 3.4E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 3.4E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.3E-20 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-20 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.3E-20 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.3E-20 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16770 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.3E-20 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 Gene3D G3DSA:3.40.47.10 4 130 7.4E-55 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 Gene3D G3DSA:3.40.47.10 204 282 7.4E-55 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 SUPERFAMILY SSF53901 278 398 9.75E-32 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 PIRSF PIRSF000429 1 399 1.5E-106 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 Pfam PF02803 Thiolase, C-terminal domain 277 398 1.5E-33 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 09-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 Gene3D G3DSA:3.40.47.10 283 398 1.6E-43 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 Gene3D G3DSA:3.40.47.10 165 203 1.6E-43 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 1.2E-113 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 SUPERFAMILY SSF53901 4 275 5.01E-62 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS00820 82f546d8207ea756fe368f8e16e54421 399 Pfam PF00108 Thiolase, N-terminal domain 5 268 1.2E-55 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 UA74_RS00185 afbff3fc73cef472ba6efc0ed9846cff 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 6.3E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS00185 afbff3fc73cef472ba6efc0ed9846cff 213 Gene3D G3DSA:1.10.357.10 19 208 9.5E-29 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS00185 afbff3fc73cef472ba6efc0ed9846cff 213 SUPERFAMILY SSF46689 14 95 5.99E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS00185 afbff3fc73cef472ba6efc0ed9846cff 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 41 72 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS00185 afbff3fc73cef472ba6efc0ed9846cff 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 2.0E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS00185 afbff3fc73cef472ba6efc0ed9846cff 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 2.0E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS07755 3139c1deb040d67d852ded6c75b7599f 134 Gene3D G3DSA:1.10.10.10 4 77 6.8E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07755 3139c1deb040d67d852ded6c75b7599f 134 SUPERFAMILY SSF46785 6 80 7.26E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07755 3139c1deb040d67d852ded6c75b7599f 134 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 2.1E-11 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS07755 3139c1deb040d67d852ded6c75b7599f 134 SMART SM00345 17 76 4.5E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 SMART SM00344 1 108 7.3E-42 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 09-03-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 Gene3D G3DSA:1.10.10.10 2 53 5.2E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 Gene3D G3DSA:3.30.70.920 54 134 4.4E-23 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 SUPERFAMILY SSF54909 61 143 4.02E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.6E-14 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.6E-14 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.6E-14 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 SUPERFAMILY SSF46785 1 60 1.57E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 5.0E-18 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02405 39323b82a4681dfa45e1ff3b05ff7ee3 160 Pfam PF01037 Lrp/AsnC ligand binding domain 75 138 1.6E-17 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS26650 a4265845921fb3f7d1fd0f9db0b7a29e 206 Gene3D G3DSA:3.40.50.1820 23 195 6.8E-20 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26650 a4265845921fb3f7d1fd0f9db0b7a29e 206 SUPERFAMILY SSF53474 4 200 2.09E-19 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 196 209 4.1E-15 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 109 127 4.1E-15 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 366 388 4.1E-15 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 182 195 4.1E-15 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 137 152 4.1E-15 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 Pfam PF06441 Epoxide hydrolase N terminus 15 117 1.1E-31 T 09-03-2017 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 Gene3D G3DSA:3.40.50.1820 6 391 1.7E-128 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 SUPERFAMILY SSF53474 8 391 3.12E-97 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06875 085848547c5a763020c7d28bddf56b4d 392 PIRSF PIRSF001112 2 392 3.9E-105 T 09-03-2017 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 UA74_RS24570 3cc4832157a70fd477100a37e589f78a 257 Pfam PF11967 Recombination protein O N terminal 1 79 1.3E-25 T 09-03-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal UA74_RS24570 3cc4832157a70fd477100a37e589f78a 257 SUPERFAMILY SSF57863 83 232 1.2E-39 T 09-03-2017 UA74_RS24570 3cc4832157a70fd477100a37e589f78a 257 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 26.263 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UA74_RS24570 3cc4832157a70fd477100a37e589f78a 257 Pfam PF02565 Recombination protein O C terminal 85 238 5.5E-36 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UA74_RS24570 3cc4832157a70fd477100a37e589f78a 257 SUPERFAMILY SSF50249 1 79 1.88E-19 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS24570 3cc4832157a70fd477100a37e589f78a 257 Gene3D G3DSA:2.40.50.140 1 80 3.5E-37 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS24570 3cc4832157a70fd477100a37e589f78a 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 206 1.6E-31 T 09-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UA74_RS29695 50aff8466b6b3ce0c4ee14ff8bac2dde 399 SUPERFAMILY SSF55874 283 393 2.11E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS29695 50aff8466b6b3ce0c4ee14ff8bac2dde 399 Gene3D G3DSA:3.30.565.10 305 394 4.6E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS29695 50aff8466b6b3ce0c4ee14ff8bac2dde 399 Pfam PF07730 Histidine kinase 189 254 3.0E-16 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS11605 a72a7389c0f0eba6b92ec143b44e3723 323 Pfam PF13519 von Willebrand factor type A domain 94 206 2.1E-19 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS11605 a72a7389c0f0eba6b92ec143b44e3723 323 Pfam PF07584 Aerotolerance regulator N-terminal 9 81 3.5E-8 T 09-03-2017 IPR024163 Aerotolerance regulator, N-terminal UA74_RS11605 a72a7389c0f0eba6b92ec143b44e3723 323 Gene3D G3DSA:3.40.50.410 88 287 9.0E-21 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS11605 a72a7389c0f0eba6b92ec143b44e3723 323 SUPERFAMILY SSF53300 88 285 5.29E-29 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS11605 a72a7389c0f0eba6b92ec143b44e3723 323 SMART SM00327 91 288 3.6E-23 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 Gene3D G3DSA:1.10.10.10 5 78 1.6E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 SMART SM00895 87 211 1.2E-17 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 SMART SM00345 19 77 4.8E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 SUPERFAMILY SSF46785 10 81 2.63E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 9.9E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 SUPERFAMILY SSF48008 86 215 2.88E-25 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 Gene3D G3DSA:1.20.120.530 82 212 2.1E-26 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS17055 c3a4a3942801f3b8d1c237014a725d38 225 Pfam PF07729 FCD domain 87 209 1.1E-23 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS18125 aee28f71a8486707201c3c75e25023c4 546 SUPERFAMILY SSF51445 18 472 1.67E-130 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS18125 aee28f71a8486707201c3c75e25023c4 546 Pfam PF11941 Domain of unknown function (DUF3459) 458 544 4.3E-10 T 09-03-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) UA74_RS18125 aee28f71a8486707201c3c75e25023c4 546 SMART SM00642 28 410 3.1E-126 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS18125 aee28f71a8486707201c3c75e25023c4 546 Pfam PF00128 Alpha amylase, catalytic domain 43 381 2.9E-80 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS18125 aee28f71a8486707201c3c75e25023c4 546 Gene3D G3DSA:3.20.20.80 18 119 4.8E-112 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS18125 aee28f71a8486707201c3c75e25023c4 546 Gene3D G3DSA:3.20.20.80 193 473 4.8E-112 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS18125 aee28f71a8486707201c3c75e25023c4 546 Gene3D G3DSA:3.90.400.10 120 191 3.2E-29 T 09-03-2017 UA74_RS11525 59a828c77656b183e5467f96c396fd57 243 Gene3D G3DSA:3.60.20.10 45 234 5.3E-33 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS11525 59a828c77656b183e5467f96c396fd57 243 Pfam PF13522 Glutamine amidotransferase domain 62 205 2.8E-13 T 09-03-2017 UA74_RS11525 59a828c77656b183e5467f96c396fd57 243 SUPERFAMILY SSF56235 46 233 3.28E-17 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS16085 137ef80c468961cd9e3955c29bdd3ddd 313 Gene3D G3DSA:3.90.1580.10 102 303 1.5E-43 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 UA74_RS16085 137ef80c468961cd9e3955c29bdd3ddd 313 Pfam PF13560 Helix-turn-helix domain 9 63 7.7E-7 T 09-03-2017 UA74_RS16085 137ef80c468961cd9e3955c29bdd3ddd 313 SMART SM00530 11 64 0.0053 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS16085 137ef80c468961cd9e3955c29bdd3ddd 313 Pfam PF03781 Sulfatase-modifying factor enzyme 1 121 301 3.6E-35 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 UA74_RS16085 137ef80c468961cd9e3955c29bdd3ddd 313 SUPERFAMILY SSF56436 109 303 8.95E-50 T 09-03-2017 IPR016187 C-type lectin fold UA74_RS16085 137ef80c468961cd9e3955c29bdd3ddd 313 Gene3D G3DSA:1.10.260.40 11 44 6.2E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16085 137ef80c468961cd9e3955c29bdd3ddd 313 SUPERFAMILY SSF47413 7 45 2.51E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 4228 4484 3.66E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08990 Erythronolide synthase docking 2 26 6.1E-12 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 2510 2694 3.33E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4231 4411 8.1E-48 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1209 1388 2.5E-45 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2705 2885 1.1E-57 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 1582 1842 5.8E-88 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 35 295 1.6E-84 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 3082 3335 4.8E-87 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF55048 723 784 8.5E-11 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3236 3252 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00823 Phosphopantetheine attachment site 1489 1561 5.1E-31 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00823 Phosphopantetheine attachment site 2988 3060 5.1E-28 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00823 Phosphopantetheine attachment site 4515 4587 7.9E-29 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 1203 1463 8.0E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00698 Acyl transferase domain 2111 2422 6.0E-50 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00698 Acyl transferase domain 592 907 1.7E-52 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00698 Acyl transferase domain 3601 3941 5.6E-47 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00550 Phosphopantetheine attachment site 2990 3056 2.8E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00550 Phosphopantetheine attachment site 4517 4582 2.9E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00550 Phosphopantetheine attachment site 1492 1557 7.4E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00825 Beta-ketoacyl synthase 35 461 3.6E-209 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00825 Beta-ketoacyl synthase 1582 2008 7.8E-221 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00825 Beta-ketoacyl synthase 3082 3501 6.5E-206 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM01294 1490 1557 1.4E-6 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM01294 2989 3056 1.0E-5 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM01294 4516 4583 1.9E-7 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF47336 4509 4596 4.84E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.30.70.250 722 783 2.2E-6 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.30.70.250 2238 2298 5.6E-7 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.30.70.250 3729 3812 3.8E-6 T 09-03-2017 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3331 3448 1.2E-40 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1838 1955 7.0E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 6.6E-42 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF47336 2986 3095 1.83E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.50.720 1208 1391 4.9E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.50.720 4470 4484 6.8E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.50.720 2705 2915 7.6E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.50.720 4230 4413 6.8E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF47336 1485 1595 2.36E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1516 1531 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF101173 2 30 9.42E-5 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 2104 2233 5.3E-75 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 2299 2409 5.3E-75 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 584 718 8.1E-75 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 3813 3921 3.3E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 3594 3724 3.3E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 784 893 8.1E-75 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 2107 2239 1.41E-68 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 2300 2397 1.41E-68 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 2702 2936 1.42E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:1.10.1200.10 4512 4585 4.2E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:1.10.1200.10 1486 1562 1.6E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:1.10.1200.10 2986 3060 3.4E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1580 1830 2.8E-88 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3080 3323 1.1E-83 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 4.6E-84 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF53901 29 404 1.59E-93 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 589 724 2.01E-68 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 785 882 2.01E-68 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 4026 4218 1.55E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3602 3922 1.9E-107 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 592 889 1.4E-112 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2111 2404 2.4E-113 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 989 1196 4.33E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08659 KR domain 4231 4409 1.9E-60 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08659 KR domain 2705 2883 1.0E-62 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08659 KR domain 1209 1386 3.6E-54 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF53901 1578 1952 3.32E-104 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3451 3562 7.0E-15 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1958 2074 5.8E-16 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 555 2.8E-12 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF53901 3078 3438 6.98E-99 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 3336 3501 1.7E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 296 461 5.0E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 1843 2008 6.7E-66 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3015 3030 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1743 1759 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF55048 3729 3813 3.79E-8 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF55048 2238 2299 2.35E-11 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 3814 3908 1.36E-64 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16495 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 3599 3730 1.36E-64 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS05465 0380d3e5fb3e29b3691f85fc2ba05bc1 365 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 72 283 1.1E-20 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_RS05465 0380d3e5fb3e29b3691f85fc2ba05bc1 365 Gene3D G3DSA:2.120.10.30 21 351 1.3E-49 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS05465 0380d3e5fb3e29b3691f85fc2ba05bc1 365 SUPERFAMILY SSF63829 34 283 2.62E-47 T 09-03-2017 UA74_RS05465 0380d3e5fb3e29b3691f85fc2ba05bc1 365 SUPERFAMILY SSF63829 316 343 2.62E-47 T 09-03-2017 UA74_RS15140 448cbd6657698507997f3972dee5f040 227 SUPERFAMILY SSF46689 20 91 1.99E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15140 448cbd6657698507997f3972dee5f040 227 Gene3D G3DSA:1.10.357.10 19 208 7.4E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15140 448cbd6657698507997f3972dee5f040 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.2E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15140 448cbd6657698507997f3972dee5f040 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.2E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15140 448cbd6657698507997f3972dee5f040 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 2.1E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS12240 587bb062b43ced7d8ea60b2d847b4f8e 300 Pfam PF13302 Acetyltransferase (GNAT) domain 8 145 2.0E-16 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS12240 587bb062b43ced7d8ea60b2d847b4f8e 300 Gene3D G3DSA:3.10.180.10 166 294 8.1E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS12240 587bb062b43ced7d8ea60b2d847b4f8e 300 SUPERFAMILY SSF54593 167 296 1.69E-17 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS12240 587bb062b43ced7d8ea60b2d847b4f8e 300 Gene3D G3DSA:3.40.630.30 2 160 4.0E-29 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS12240 587bb062b43ced7d8ea60b2d847b4f8e 300 SUPERFAMILY SSF55729 1 150 1.79E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS12240 587bb062b43ced7d8ea60b2d847b4f8e 300 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 171 273 2.3E-8 T 09-03-2017 UA74_RS13430 afcb23038e0932b7980f070b89095486 500 Gene3D G3DSA:3.40.50.300 275 494 3.0E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13430 afcb23038e0932b7980f070b89095486 500 Gene3D G3DSA:3.40.50.300 10 245 7.5E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13430 afcb23038e0932b7980f070b89095486 500 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13430 afcb23038e0932b7980f070b89095486 500 SUPERFAMILY SSF52540 273 484 1.87E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13430 afcb23038e0932b7980f070b89095486 500 SUPERFAMILY SSF52540 10 232 8.37E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13430 afcb23038e0932b7980f070b89095486 500 SMART SM00382 284 494 0.1 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13430 afcb23038e0932b7980f070b89095486 500 SMART SM00382 33 221 1.6E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13430 afcb23038e0932b7980f070b89095486 500 Pfam PF00005 ABC transporter 26 173 9.6E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13430 afcb23038e0932b7980f070b89095486 500 Pfam PF00005 ABC transporter 277 429 6.8E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS25550 df89d959af7626137641082735069c01 292 Gene3D G3DSA:1.10.260.40 5 70 1.8E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25550 df89d959af7626137641082735069c01 292 Pfam PF13560 Helix-turn-helix domain 13 72 4.5E-11 T 09-03-2017 UA74_RS25550 df89d959af7626137641082735069c01 292 SUPERFAMILY SSF47413 10 74 6.52E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25550 df89d959af7626137641082735069c01 292 SMART SM00530 17 72 7.9E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF47336 521 625 1.22E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF52777 786 1033 1.89E-44 T 09-03-2017 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:3.40.50.980 7 154 3.3E-41 T 09-03-2017 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 33 442 1.7E-106 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF56801 7 539 1.96E-129 T 09-03-2017 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 495 8.3E-9 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:3.40.50.980 155 314 1.3E-31 T 09-03-2017 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF13745 HxxPF-repeated domain 922 1012 5.2E-13 T 09-03-2017 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 SMART SM00823 Phosphopantetheine attachment site 526 595 0.0065 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF00550 Phosphopantetheine attachment site 528 589 3.8E-8 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF00501 AMP-binding enzyme 13 418 1.8E-79 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:1.10.1200.10 530 595 1.3E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF52777 617 780 2.78E-41 T 09-03-2017 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 ProSitePatterns PS00012 Phosphopantetheine attachment site. 550 565 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:3.30.300.30 414 529 1.8E-26 T 09-03-2017 UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF00668 Condensation domain 614 898 8.0E-57 T 09-03-2017 IPR001242 Condensation domain UA74_RS05225 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:2.30.38.10 327 408 2.6E-21 T 09-03-2017 UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 Gene3D G3DSA:3.40.47.10 263 406 1.3E-50 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 Gene3D G3DSA:3.40.47.10 8 259 4.8E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 SMART SM00825 Beta-ketoacyl synthase 6 399 4.4E-14 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 SUPERFAMILY SSF53901 214 406 3.05E-62 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 365 6.5E-33 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 SUPERFAMILY SSF53901 4 251 1.26E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS25600 eb3112f90de983bbcb33147fda8ccdee 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 244 9.3E-55 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS30075 37b746e983ed98953423fd544dcf24b9 277 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 72 85 - T 09-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 UA74_RS30075 37b746e983ed98953423fd544dcf24b9 277 Gene3D G3DSA:3.40.190.10 129 233 4.8E-17 T 09-03-2017 UA74_RS30075 37b746e983ed98953423fd544dcf24b9 277 SMART SM00062 51 273 3.8E-43 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS30075 37b746e983ed98953423fd544dcf24b9 277 Gene3D G3DSA:3.40.190.10 234 272 1.9E-33 T 09-03-2017 UA74_RS30075 37b746e983ed98953423fd544dcf24b9 277 Gene3D G3DSA:3.40.190.10 51 128 1.9E-33 T 09-03-2017 UA74_RS30075 37b746e983ed98953423fd544dcf24b9 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 55 271 2.1E-51 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS30075 37b746e983ed98953423fd544dcf24b9 277 SUPERFAMILY SSF53850 10 271 1.09E-53 T 09-03-2017 UA74_RS07985 82d3d4242e7a0e7846a4012f1d3b0f1a 531 SUPERFAMILY SSF51445 16 468 6.04E-121 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07985 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Pfam PF11941 Domain of unknown function (DUF3459) 454 530 1.2E-7 T 09-03-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) UA74_RS07985 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Pfam PF00128 Alpha amylase, catalytic domain 40 383 3.4E-78 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07985 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Gene3D G3DSA:3.90.400.10 117 189 2.4E-32 T 09-03-2017 UA74_RS07985 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Gene3D G3DSA:3.20.20.80 190 469 7.0E-105 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07985 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Gene3D G3DSA:3.20.20.80 16 116 7.0E-105 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07985 82d3d4242e7a0e7846a4012f1d3b0f1a 531 SMART SM00642 25 408 1.1E-110 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS30280 45a1b100da811219657601317b2bee46 399 SUPERFAMILY SSF55874 282 390 4.45E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS30280 45a1b100da811219657601317b2bee46 399 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 297 389 8.5E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS30280 45a1b100da811219657601317b2bee46 399 Gene3D G3DSA:3.30.565.10 292 390 4.7E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS27620 817469340d757766c8c8ea02d33c9a0e 247 Pfam PF01061 ABC-2 type transporter 10 210 8.1E-11 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS27620 817469340d757766c8c8ea02d33c9a0e 247 PIRSF PIRSF006648 3 245 4.1E-20 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 Gene3D G3DSA:2.40.50.140 1 123 5.1E-65 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 SUPERFAMILY SSF50249 2 123 2.31E-52 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 3.9E-68 T 09-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.92 T 09-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 PIRSF PIRSF002133 1 124 1.8E-54 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 Pfam PF00164 Ribosomal protein S12/S23 3 123 5.3E-44 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.3E-58 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.3E-58 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.3E-58 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.3E-58 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.3E-58 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02905 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.3E-58 T 09-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 SUPERFAMILY SSF47323 669 908 5.05E-42 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 Gene3D G3DSA:1.10.730.10 657 841 1.3E-37 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 648 2.0E-181 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 14 1053 13.828 T 09-03-2017 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 Pfam PF08264 Anticodon-binding domain of tRNA 710 849 4.9E-20 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 Gene3D G3DSA:3.90.740.10 223 392 3.7E-56 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 236 259 1.7E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 404 419 1.7E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 56 67 1.7E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 573 582 1.7E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 533 546 1.7E-30 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 SUPERFAMILY SSF52374 406 647 6.17E-123 T 09-03-2017 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 SUPERFAMILY SSF52374 20 213 6.17E-123 T 09-03-2017 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 Gene3D G3DSA:3.40.50.620 409 645 5.9E-140 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS09805 7668335c053980b4947dbc302857895a 1054 Gene3D G3DSA:3.40.50.620 21 209 5.9E-140 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS09805 7668335c053980b4947dbc302857895a 1054 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 18 861 6.5E-242 T 09-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 SUPERFAMILY SSF50677 217 406 5.55E-50 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS09805 7668335c053980b4947dbc302857895a 1054 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 63 74 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS05405 988bbef928a71b3a4f318850e61b68a6 178 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 49 117 5.9E-5 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS05405 988bbef928a71b3a4f318850e61b68a6 178 SUPERFAMILY SSF50475 39 161 6.24E-14 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS05405 988bbef928a71b3a4f318850e61b68a6 178 Gene3D G3DSA:2.30.110.10 36 165 1.1E-10 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 SMART SM00345 16 75 5.8E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 Gene3D G3DSA:1.10.10.10 5 78 8.9E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 Gene3D G3DSA:1.10.3210.10 96 210 2.2E-26 T 09-03-2017 IPR006674 HD domain UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 SMART SM00471 119 313 0.0091 T 09-03-2017 IPR003607 HD/PDEase domain UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 Pfam PF13023 HD domain 102 209 8.1E-20 T 09-03-2017 IPR006674 HD domain UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 SUPERFAMILY SSF109604 96 210 3.77E-23 T 09-03-2017 UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 SUPERFAMILY SSF46785 5 84 8.95E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05785 4386df7227dbfb2685a4c218aa7df7f4 314 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 2.8E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20115 9967c32ab3dc7e56ca34cfb2865a0c6f 126 Pfam PF01042 Endoribonuclease L-PSP 12 123 4.2E-24 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family UA74_RS20115 9967c32ab3dc7e56ca34cfb2865a0c6f 126 Gene3D G3DSA:3.30.1330.40 2 124 7.0E-35 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS20115 9967c32ab3dc7e56ca34cfb2865a0c6f 126 SUPERFAMILY SSF55298 2 124 5.18E-32 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS04910 5ccf9304e6cce880a6557a0c1a2f2965 183 Pfam PF01863 Protein of unknown function DUF45 63 151 8.3E-21 T 09-03-2017 IPR002725 Protein of unknown function DUF45 UA74_RS20120 3bd2d7a1b0ddbd3f15069423d01c2fb2 411 SUPERFAMILY SSF53383 61 369 9.5E-26 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS20120 3bd2d7a1b0ddbd3f15069423d01c2fb2 411 Gene3D G3DSA:3.40.640.10 61 266 1.5E-17 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS08530 0fbd0ba72565bbfd6f7a8cba447b8599 253 Gene3D G3DSA:3.30.420.40 112 249 1.2E-33 T 09-03-2017 UA74_RS08530 0fbd0ba72565bbfd6f7a8cba447b8599 253 Gene3D G3DSA:3.30.420.40 5 104 2.9E-38 T 09-03-2017 UA74_RS08530 0fbd0ba72565bbfd6f7a8cba447b8599 253 SUPERFAMILY SSF53067 8 248 1.19E-32 T 09-03-2017 UA74_RS08530 0fbd0ba72565bbfd6f7a8cba447b8599 253 Pfam PF00480 ROK family 9 168 2.1E-14 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 SMART SM00836 187 314 3.7E-14 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 Gene3D G3DSA:3.30.1360.70 5 109 8.4E-11 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 Gene3D G3DSA:3.40.50.620 145 186 6.9E-5 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 Gene3D G3DSA:1.10.730.10 187 314 7.6E-24 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 Pfam PF05746 DALR anticodon binding domain 187 314 1.9E-16 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 41 94 6.9E-7 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 SUPERFAMILY SSF47323 182 314 2.35E-16 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 SUPERFAMILY SSF55190 42 106 9.81E-7 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS07065 819003a8a61b8eb246ac3a5151abeb08 314 SMART SM01016 4 95 2.7E-9 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 Pfam PF00108 Thiolase, N-terminal domain 5 213 1.2E-17 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 Pfam PF02803 Thiolase, C-terminal domain 253 346 1.1E-11 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 Gene3D G3DSA:3.40.47.10 136 173 8.1E-22 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 Gene3D G3DSA:3.40.47.10 233 364 8.1E-22 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 SUPERFAMILY SSF53901 234 364 6.15E-31 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 ProSitePatterns PS00737 Thiolases signature 2. 313 329 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 Gene3D G3DSA:3.40.47.10 188 213 7.9E-26 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 Gene3D G3DSA:3.40.47.10 10 111 7.9E-26 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 SUPERFAMILY SSF53901 4 220 1.25E-43 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22410 f3df40b22091f69ecd564fa63e70a5a0 381 PIRSF PIRSF000429 1 367 5.5E-58 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 Gene3D G3DSA:3.40.50.2300 83 198 8.6E-17 T 09-03-2017 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 Gene3D G3DSA:1.10.10.10 7 56 1.1E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 Pfam PF13377 Periplasmic binding protein-like domain 195 358 1.3E-31 T 09-03-2017 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 SMART SM00420 7 59 1.2E-10 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 SUPERFAMILY SSF53822 83 359 1.31E-34 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 SUPERFAMILY SSF46785 6 59 3.52E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 Gene3D G3DSA:3.40.50.2300 199 359 5.5E-30 T 09-03-2017 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 1.4E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 1.4E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS24260 588b39601bf83343fceaa2c263a1fc61 363 Pfam PF08220 DeoR-like helix-turn-helix domain 7 60 3.2E-12 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS22795 24771340f096fc3947ed89e79e337d52 425 Pfam PF13378 Enolase C-terminal domain-like 175 388 4.1E-52 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS22795 24771340f096fc3947ed89e79e337d52 425 SUPERFAMILY SSF54826 6 138 1.31E-24 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS22795 24771340f096fc3947ed89e79e337d52 425 SUPERFAMILY SSF51604 138 397 1.57E-75 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS22795 24771340f096fc3947ed89e79e337d52 425 Gene3D G3DSA:3.20.20.120 122 381 8.7E-93 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS22795 24771340f096fc3947ed89e79e337d52 425 SMART SM00922 172 266 5.4E-26 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS22795 24771340f096fc3947ed89e79e337d52 425 Gene3D G3DSA:3.30.390.10 7 121 2.8E-12 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS22795 24771340f096fc3947ed89e79e337d52 425 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 37 138 2.1E-4 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 PIRSF PIRSF000106 23 461 3.4E-77 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 Pfam PF00390 Malic enzyme, N-terminal domain 94 225 3.8E-27 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 PRINTS PR00072 Malic enzyme signature 154 176 2.0E-6 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 PRINTS PR00072 Malic enzyme signature 233 249 2.0E-6 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 PRINTS PR00072 Malic enzyme signature 264 280 2.0E-6 T 09-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 Gene3D G3DSA:3.40.50.10380 92 234 6.7E-53 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 SMART SM00919 237 459 1.6E-102 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 SUPERFAMILY SSF53223 86 235 2.52E-55 T 09-03-2017 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 Gene3D G3DSA:3.40.50.720 235 458 1.1E-68 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 SUPERFAMILY SSF51735 237 460 5.71E-67 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 Pfam PF03949 Malic enzyme, NAD binding domain 239 458 2.1E-22 T 09-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 UA74_RS28605 7031ed661269f889b1b3653f7d11c5a9 461 SMART SM01274 92 225 2.5E-82 T 09-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_RS29725 f71f4b363f99164534e53a2b166881ba 690 SUPERFAMILY SSF53067 4 155 9.54E-25 T 09-03-2017 UA74_RS29725 f71f4b363f99164534e53a2b166881ba 690 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 314 328 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS29725 f71f4b363f99164534e53a2b166881ba 690 SUPERFAMILY SSF53067 169 353 1.3E-30 T 09-03-2017 UA74_RS29725 f71f4b363f99164534e53a2b166881ba 690 Gene3D G3DSA:3.30.420.40 179 339 4.9E-18 T 09-03-2017 UA74_RS29725 f71f4b363f99164534e53a2b166881ba 690 Pfam PF00012 Hsp70 protein 89 352 1.4E-29 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29725 f71f4b363f99164534e53a2b166881ba 690 Gene3D G3DSA:3.30.420.40 4 178 1.2E-24 T 09-03-2017 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 61.39 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 SUPERFAMILY SSF52304 2 142 4.45E-55 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 Pfam PF01220 Dehydroquinase class II 3 138 3.1E-52 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 141 1.6E-56 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 Gene3D G3DSA:3.40.50.9100 2 142 4.7E-57 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 09-03-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 PIRSF PIRSF001399 1 144 2.7E-56 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS12235 5e915fe8076cbb7645885e7d59bdaead 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 140 2.0E-41 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS05765 29130a588b7e80dd8aeace41dd0b5ec7 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 363 2.4E-111 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_RS05765 29130a588b7e80dd8aeace41dd0b5ec7 369 Gene3D G3DSA:3.90.1150.10 247 367 4.3E-37 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS05765 29130a588b7e80dd8aeace41dd0b5ec7 369 Gene3D G3DSA:3.40.640.10 17 245 4.2E-72 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS05765 29130a588b7e80dd8aeace41dd0b5ec7 369 PIRSF PIRSF000390 3 368 6.7E-100 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_RS05765 29130a588b7e80dd8aeace41dd0b5ec7 369 SUPERFAMILY SSF53383 8 366 4.81E-102 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 6.2E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 6.2E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 SUPERFAMILY SSF48008 110 245 1.7E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 SMART SM00345 28 87 2.3E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 Gene3D G3DSA:1.20.120.530 110 246 6.9E-31 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 SUPERFAMILY SSF46785 20 89 1.93E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 Pfam PF07729 FCD domain 112 236 5.2E-27 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 SMART SM00895 112 237 6.1E-24 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 86 1.1E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20065 36d669ad20b83c8cbdd54a1d491bc0bb 268 Gene3D G3DSA:1.10.10.10 22 88 3.9E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07195 4b42761ac978fd715e8d69a61c8e245b 136 Pfam PF10739 Protein of unknown function (DUF2550) 3 129 2.8E-44 T 09-03-2017 IPR019675 Protein of unknown function DUF2550 UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 Gene3D G3DSA:3.40.50.300 66 286 7.2E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 Pfam PF00270 DEAD/DEAH box helicase 80 272 4.0E-16 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 SUPERFAMILY SSF52540 1037 1149 5.63E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 SUPERFAMILY SSF52540 98 156 5.63E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 SMART SM00487 73 315 7.5E-15 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 SUPERFAMILY SSF52540 65 284 2.94E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 SMART SM00490 1038 1123 5.0E-14 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 Gene3D G3DSA:3.40.50.300 1040 1151 1.2E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 Pfam PF00271 Helicase conserved C-terminal domain 1049 1121 2.9E-9 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS19200 faf07751241f7cff5229a3a075e6dd8e 2235 Pfam PF09369 Domain of unknown function (DUF1998) 1625 1711 4.2E-8 T 09-03-2017 IPR018973 DEAD/DEAH-box helicase, putative UA74_RS29010 f4a767426d8665a40e7b652d929164bd 417 Gene3D G3DSA:3.40.50.150 86 254 9.1E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS29010 f4a767426d8665a40e7b652d929164bd 417 Pfam PF08421 Putative zinc binding domain 3 64 5.8E-20 T 09-03-2017 IPR013630 Methyltransferase putative zinc binding domain UA74_RS29010 f4a767426d8665a40e7b652d929164bd 417 SUPERFAMILY SSF53335 60 249 7.04E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS29010 f4a767426d8665a40e7b652d929164bd 417 Pfam PF08484 C-methyltransferase C-terminal domain 244 401 3.5E-58 T 09-03-2017 IPR013691 C-methyltransferase UA74_RS29010 f4a767426d8665a40e7b652d929164bd 417 Pfam PF13489 Methyltransferase domain 79 237 8.0E-12 T 09-03-2017 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:3.40.50.300 13 202 6.5E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 16 468 7.6E-148 T 09-03-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:1.10.150.80 547 612 3.7E-18 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00490 252 333 1.2E-23 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 SUPERFAMILY SSF52540 209 461 1.71E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:1.10.10.10 347 521 1.4E-53 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 16 611 2.0E-229 T 09-03-2017 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00487 23 217 8.1E-29 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF09382 RQC domain 408 521 1.5E-34 T 09-03-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF00570 HRDC domain 547 610 2.3E-22 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00956 413 519 1.6E-43 T 09-03-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF00271 Helicase conserved C-terminal domain 226 333 1.6E-14 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 SUPERFAMILY SSF52540 13 198 5.33E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF16124 RecQ zinc-binding 345 406 6.4E-17 T 09-03-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF00270 DEAD/DEAH box helicase 30 187 1.2E-17 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:3.40.50.300 208 346 1.2E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00341 541 612 4.0E-8 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS10610 9df65b058af21be22f7cdfc4b2d49acf 613 SUPERFAMILY SSF47819 541 612 8.72E-21 T 09-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 SMART SM00278 11 30 0.0081 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 100.389 T 09-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 Pfam PF13662 Toprim domain 80 175 6.8E-22 T 09-03-2017 IPR006171 Toprim domain UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 SUPERFAMILY SSF111304 2 202 3.92E-68 T 09-03-2017 IPR023627 Recombination protein RecR UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 Pfam PF02132 RecR protein 38 77 2.4E-13 T 09-03-2017 IPR023628 Recombination protein RecR, C4-type zinc finger UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 TIGRFAM TIGR00615 recR: recombination protein RecR 2 200 8.5E-79 T 09-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 SMART SM00493 79 168 3.8E-15 T 09-03-2017 IPR006171 Toprim domain UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 Gene3D G3DSA:3.40.50.140 138 173 2.6E-5 T 09-03-2017 IPR006171 Toprim domain UA74_RS01010 60836c8ddd590a2e77c6d7b292e645de 202 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 09-03-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 UA74_RS28830 4382a8d70cb80ff5e1112a9ceb592271 256 SUPERFAMILY SSF51735 3 224 6.39E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28830 4382a8d70cb80ff5e1112a9ceb592271 256 Gene3D G3DSA:3.40.50.720 4 222 5.9E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28830 4382a8d70cb80ff5e1112a9ceb592271 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS28830 4382a8d70cb80ff5e1112a9ceb592271 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS28830 4382a8d70cb80ff5e1112a9ceb592271 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS28830 4382a8d70cb80ff5e1112a9ceb592271 256 Pfam PF00106 short chain dehydrogenase 4 191 2.8E-20 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20955 33831c06c8fada72f9b9ddf53beeec72 1009 SUPERFAMILY SSF52129 15 216 1.06E-17 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS20955 33831c06c8fada72f9b9ddf53beeec72 1009 Gene3D G3DSA:3.40.50.1460 17 159 2.8E-6 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS20955 33831c06c8fada72f9b9ddf53beeec72 1009 Pfam PF00656 Caspase domain 19 213 6.1E-13 T 09-03-2017 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 SUPERFAMILY SSF47203 226 378 1.18E-55 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 PIRSF PIRSF016578 3 379 2.4E-20 T 09-03-2017 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 SUPERFAMILY SSF56645 2 240 5.76E-84 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 3.7E-52 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 2.2E-28 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 8.0E-36 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 Gene3D G3DSA:1.20.140.10 217 378 7.6E-67 T 09-03-2017 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 Gene3D G3DSA:1.10.540.10 1 118 9.7E-42 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13675 fbaa355c131db894fcdb38b03a298fff 383 Gene3D G3DSA:2.40.110.10 121 216 4.7E-38 T 09-03-2017 UA74_RS16855 23c86c6f3850465bf800b903e86874a7 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 3.6E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS16855 23c86c6f3850465bf800b903e86874a7 223 SUPERFAMILY SSF46689 2 61 1.55E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS16855 23c86c6f3850465bf800b903e86874a7 223 Pfam PF13305 WHG domain 78 126 3.3E-6 T 09-03-2017 IPR025996 WHG domain UA74_RS16855 23c86c6f3850465bf800b903e86874a7 223 SUPERFAMILY SSF48498 69 136 1.4E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS16855 23c86c6f3850465bf800b903e86874a7 223 Gene3D G3DSA:1.10.357.10 2 152 2.7E-25 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS05390 4ec472b10727db4f394d873e833bb57e 497 Pfam PF00561 alpha/beta hydrolase fold 93 469 5.4E-29 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05390 4ec472b10727db4f394d873e833bb57e 497 SUPERFAMILY SSF53474 179 343 2.75E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05390 4ec472b10727db4f394d873e833bb57e 497 SUPERFAMILY SSF53474 393 467 2.75E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05390 4ec472b10727db4f394d873e833bb57e 497 SUPERFAMILY SSF53474 70 139 2.75E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05390 4ec472b10727db4f394d873e833bb57e 497 Gene3D G3DSA:3.40.50.1820 363 482 2.9E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05390 4ec472b10727db4f394d873e833bb57e 497 Gene3D G3DSA:3.40.50.1820 58 144 2.9E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05390 4ec472b10727db4f394d873e833bb57e 497 Gene3D G3DSA:3.40.50.1820 189 313 2.9E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 PIRSF PIRSF002191 1 119 4.4E-51 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 09-03-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 3.0E-49 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 Pfam PF01245 Ribosomal protein L19 4 112 3.2E-50 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 SUPERFAMILY SSF50104 1 114 1.0E-46 T 09-03-2017 IPR008991 Translation protein SH3-like domain UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.734 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.3E-41 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.3E-41 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08945 b0a9a74d3681d02a3f7f1112ed0a7169 119 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.3E-41 T 09-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 SUPERFAMILY SSF51905 8 347 5.11E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.8E-5 T 09-03-2017 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 3.8E-5 T 09-03-2017 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 3.8E-5 T 09-03-2017 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 338 1.5E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 9.8E-12 T 09-03-2017 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 9.8E-12 T 09-03-2017 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 9.8E-12 T 09-03-2017 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 9.8E-12 T 09-03-2017 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 Gene3D G3DSA:3.50.50.60 9 117 8.2E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03810 f722a4735f33ff4d22080835716cd24b 441 Gene3D G3DSA:3.50.50.60 118 346 3.6E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07015 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 2.0E-38 T 09-03-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS07015 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 Pfam PF06339 Ectoine synthase 2 125 6.7E-54 T 09-03-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS07015 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 SUPERFAMILY SSF51182 18 125 1.83E-19 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS07015 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 Gene3D G3DSA:2.60.120.10 18 110 4.1E-12 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS07015 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 35.544 T 09-03-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS11050 2749cb54d8fa9eb04150e9b24a5cb280 389 Gene3D G3DSA:3.40.50.2000 220 365 6.3E-26 T 09-03-2017 UA74_RS11050 2749cb54d8fa9eb04150e9b24a5cb280 389 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 277 353 5.2E-10 T 09-03-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 UA74_RS11050 2749cb54d8fa9eb04150e9b24a5cb280 389 SUPERFAMILY SSF53756 1 382 5.34E-68 T 09-03-2017 UA74_RS11050 2749cb54d8fa9eb04150e9b24a5cb280 389 Gene3D G3DSA:3.40.50.2000 1 219 9.5E-27 T 09-03-2017 UA74_RS11050 2749cb54d8fa9eb04150e9b24a5cb280 389 Pfam PF06722 Protein of unknown function (DUF1205) 177 269 1.3E-15 T 09-03-2017 IPR010610 Domain of unknown function DUF1205 UA74_RS16350 2b77c5ad3ce920f311c8be50e0a2871b 332 Gene3D G3DSA:1.10.150.130 38 136 3.1E-11 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS16350 2b77c5ad3ce920f311c8be50e0a2871b 332 Gene3D G3DSA:1.10.443.10 149 319 1.2E-19 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS16350 2b77c5ad3ce920f311c8be50e0a2871b 332 Pfam PF00589 Phage integrase family 153 311 5.1E-10 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS16350 2b77c5ad3ce920f311c8be50e0a2871b 332 SUPERFAMILY SSF56349 37 319 2.06E-36 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS04955 75650fba66382716a71073529c686098 366 SUPERFAMILY SSF75620 28 364 6.28E-118 T 09-03-2017 UA74_RS04955 75650fba66382716a71073529c686098 366 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_RS04955 75650fba66382716a71073529c686098 366 Gene3D G3DSA:3.30.160.20 227 304 4.2E-34 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain UA74_RS04955 75650fba66382716a71073529c686098 366 Pfam PF03462 PCRF domain 29 218 6.4E-52 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 UA74_RS04955 75650fba66382716a71073529c686098 366 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 362 4.7E-150 T 09-03-2017 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 UA74_RS04955 75650fba66382716a71073529c686098 366 Pfam PF00472 RF-1 domain 228 335 4.2E-37 T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_RS04955 75650fba66382716a71073529c686098 366 SMART SM00937 83 193 1.3E-42 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 UA74_RS04955 75650fba66382716a71073529c686098 366 Gene3D G3DSA:1.20.58.410 3 114 7.9E-32 T 09-03-2017 UA74_RS04955 75650fba66382716a71073529c686098 366 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 363 37.226 T 09-03-2017 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 UA74_RS27460 b2695b7303befc72dcbad3f9705466a0 207 SUPERFAMILY SSF53271 4 205 1.31E-58 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS27460 b2695b7303befc72dcbad3f9705466a0 207 Pfam PF14681 Uracil phosphoribosyltransferase 5 206 5.6E-59 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS27460 b2695b7303befc72dcbad3f9705466a0 207 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 205 2.2E-71 T 09-03-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UA74_RS27460 b2695b7303befc72dcbad3f9705466a0 207 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 38.938 T 09-03-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UA74_RS27460 b2695b7303befc72dcbad3f9705466a0 207 Gene3D G3DSA:3.40.50.2020 3 205 4.1E-66 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS12870 570d6cf079ea8292407dc45836111956 885 Gene3D G3DSA:1.10.510.10 342 407 3.4E-5 T 09-03-2017 UA74_RS12870 570d6cf079ea8292407dc45836111956 885 Gene3D G3DSA:3.30.200.20 216 306 5.6E-4 T 09-03-2017 UA74_RS12870 570d6cf079ea8292407dc45836111956 885 SUPERFAMILY SSF158745 552 869 3.01E-21 T 09-03-2017 UA74_RS12870 570d6cf079ea8292407dc45836111956 885 SMART SM01260 550 875 5.5E-6 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS12870 570d6cf079ea8292407dc45836111956 885 SUPERFAMILY SSF56112 221 405 4.65E-16 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 Pfam PF00772 DnaB-like helicase N terminal domain 18 120 3.3E-34 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 Gene3D G3DSA:3.40.50.300 180 453 1.4E-118 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 19 452 3.4E-162 T 09-03-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 SUPERFAMILY SSF48024 17 128 7.45E-38 T 09-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 SMART SM00382 213 410 9.1E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 SUPERFAMILY SSF52540 196 439 3.09E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 Pfam PF03796 DnaB-like helicase C terminal domain 196 449 4.8E-102 T 09-03-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 UA74_RS30185 ee5f76a22a1be3f5a6df447c79b65879 454 Gene3D G3DSA:1.10.860.10 19 121 2.3E-39 T 09-03-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal UA74_RS25730 c3cafca704eadc625a0ddb01120421e3 225 SMART SM00448 2 112 1.6E-41 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS25730 c3cafca704eadc625a0ddb01120421e3 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 3.2E-22 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS25730 c3cafca704eadc625a0ddb01120421e3 225 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS25730 c3cafca704eadc625a0ddb01120421e3 225 SUPERFAMILY SSF52172 1 181 2.13E-40 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS25730 c3cafca704eadc625a0ddb01120421e3 225 SMART SM00862 147 223 8.4E-23 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS25730 c3cafca704eadc625a0ddb01120421e3 225 Gene3D G3DSA:1.10.10.10 124 224 5.0E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS25730 c3cafca704eadc625a0ddb01120421e3 225 Gene3D G3DSA:3.40.50.2300 1 120 6.7E-37 T 09-03-2017 UA74_RS24645 76d16cbea048e561550c2e9fe1f0af76 306 Gene3D G3DSA:3.40.50.620 247 254 4.6E-50 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS24645 76d16cbea048e561550c2e9fe1f0af76 306 Gene3D G3DSA:3.40.50.620 13 214 4.6E-50 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS24645 76d16cbea048e561550c2e9fe1f0af76 306 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 15 306 4.8E-137 T 09-03-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 UA74_RS24645 76d16cbea048e561550c2e9fe1f0af76 306 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 36 260 1.4E-45 T 09-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 UA74_RS24645 76d16cbea048e561550c2e9fe1f0af76 306 SUPERFAMILY SSF52402 12 213 5.73E-63 T 09-03-2017 UA74_RS24645 76d16cbea048e561550c2e9fe1f0af76 306 PIRSF PIRSF002936 6 306 1.0E-132 T 09-03-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 SUPERFAMILY SSF51735 5 248 3.71E-81 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 183 0.0014 T 09-03-2017 UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.6E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.6E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.6E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 2.8E-63 T 09-03-2017 UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 Gene3D G3DSA:3.40.50.720 3 248 5.5E-83 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.8E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 6.8E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.8E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.8E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.8E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22385 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.8E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1193 1267 1.6E-20 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 Gene3D G3DSA:1.10.287.1060 77 127 8.9E-4 T 09-03-2017 UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 SUPERFAMILY SSF140453 78 150 4.32E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 PRINTS PR00394 RHS protein signature 1212 1232 2.6E-9 T 09-03-2017 IPR001826 RHS protein UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 PRINTS PR00394 RHS protein signature 1157 1177 2.6E-9 T 09-03-2017 IPR001826 RHS protein UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 PRINTS PR00394 RHS protein signature 1235 1254 2.6E-9 T 09-03-2017 IPR001826 RHS protein UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 Pfam PF05593 RHS Repeat 822 853 2.0E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 Pfam PF05593 RHS Repeat 838 874 1.4E-5 T 09-03-2017 IPR031325 RHS repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 Pfam PF05593 RHS Repeat 1074 1100 8.2E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 Pfam PF05593 RHS Repeat 859 894 2.5E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 Pfam PF05593 RHS Repeat 543 579 3.9E-7 T 09-03-2017 IPR031325 RHS repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 Pfam PF05593 RHS Repeat 996 1023 4.6E-7 T 09-03-2017 IPR031325 RHS repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 SUPERFAMILY SSF63825 753 973 1.39E-5 T 09-03-2017 UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 SUPERFAMILY SSF69304 526 673 6.8E-5 T 09-03-2017 UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 996 1022 7.3E-4 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 817 856 8.0E-7 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 522 561 1.2E-7 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 859 897 2.6E-7 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 775 815 1.8E-4 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 628 667 5.6E-5 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 608 648 2.9E-6 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1071 1106 4.3E-7 T 09-03-2017 IPR006530 YD repeat UA74_RS24925 3be6f20740a2e5917c43344954e6b40e 1541 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 545 580 1.2E-4 T 09-03-2017 IPR006530 YD repeat UA74_RS02800 7094dc15d59ab0839faecf25bf14c3ce 185 SUPERFAMILY SSF54637 7 153 4.39E-41 T 09-03-2017 IPR029069 HotDog domain UA74_RS02800 7094dc15d59ab0839faecf25bf14c3ce 185 Gene3D G3DSA:3.10.129.10 2 147 2.5E-42 T 09-03-2017 IPR029069 HotDog domain UA74_RS02800 7094dc15d59ab0839faecf25bf14c3ce 185 Pfam PF13452 N-terminal half of MaoC dehydratase 6 135 6.8E-32 T 09-03-2017 UA74_RS02800 7094dc15d59ab0839faecf25bf14c3ce 185 Hamap MF_00799 UPF0336 protein . 1 148 32.47 T 09-03-2017 IPR016709 Uncharacterised protein family UPF0336 UA74_RS14745 480e6a9016ee5580bd3d08fb3300a05a 323 Pfam PF13569 Domain of unknown function (DUF4132) 87 240 4.7E-12 T 09-03-2017 IPR025406 Domain of unknown function DUF4132 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 214 444 2.2E-81 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 SUPERFAMILY SSF52777 214 443 2.45E-80 T 09-03-2017 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 Gene3D G3DSA:4.10.320.10 134 181 1.6E-18 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 Gene3D G3DSA:3.30.559.10 204 444 3.4E-87 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 Gene3D G3DSA:2.40.50.100 1 95 9.4E-31 T 09-03-2017 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 Pfam PF02817 e3 binding domain 143 176 1.6E-14 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 SUPERFAMILY SSF51230 2 94 8.77E-27 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 SUPERFAMILY SSF47005 136 180 7.32E-12 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 Pfam PF00364 Biotin-requiring enzyme 3 73 2.6E-20 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS12005 3971d53bf2d5859a17047677bde412ad 445 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 3 444 2.7E-138 T 09-03-2017 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 09-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 Gene3D G3DSA:3.40.47.10 200 277 3.1E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 Gene3D G3DSA:3.40.47.10 4 125 3.1E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 SUPERFAMILY SSF53901 274 393 1.13E-39 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 Pfam PF02803 Thiolase, C-terminal domain 273 393 1.8E-42 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 Pfam PF00108 Thiolase, N-terminal domain 5 264 7.1E-76 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 09-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 SUPERFAMILY SSF53901 5 271 1.98E-76 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 Gene3D G3DSA:3.40.47.10 279 393 1.2E-59 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 Gene3D G3DSA:3.40.47.10 157 199 1.2E-59 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 PIRSF PIRSF000429 1 395 1.6E-130 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS13670 82c644b3288fe824046791f2ab3c8407 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 9.2E-135 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS06830 24660be55908b93e831531f24b67e90d 238 Pfam PF03713 Domain of unknown function (DUF305) 65 235 6.4E-45 T 09-03-2017 IPR005183 Domain of unknown function DUF305 UA74_RS06830 24660be55908b93e831531f24b67e90d 238 Gene3D G3DSA:1.20.1260.10 59 237 1.0E-51 T 09-03-2017 IPR012347 Ferritin-related UA74_RS27250 9b8e7122226add237bbfcbe099e7d160 389 Gene3D G3DSA:3.20.20.150 1 222 2.0E-14 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27250 9b8e7122226add237bbfcbe099e7d160 389 SUPERFAMILY SSF51658 7 249 3.08E-28 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27250 9b8e7122226add237bbfcbe099e7d160 389 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 200 207 - T 09-03-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 UA74_RS27250 9b8e7122226add237bbfcbe099e7d160 389 Pfam PF01261 Xylose isomerase-like TIM barrel 40 222 8.1E-9 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS30165 b0ce813c7d218545de9f547e3d31ad65 107 Gene3D G3DSA:3.30.70.60 10 104 7.3E-33 T 09-03-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 UA74_RS30165 b0ce813c7d218545de9f547e3d31ad65 107 SUPERFAMILY SSF54995 9 103 1.31E-31 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30165 b0ce813c7d218545de9f547e3d31ad65 107 TIGRFAM TIGR00166 S6: ribosomal protein bS6 10 103 1.2E-24 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30165 b0ce813c7d218545de9f547e3d31ad65 107 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 10 104 20.783 T 09-03-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_RS30165 b0ce813c7d218545de9f547e3d31ad65 107 Pfam PF01250 Ribosomal protein S6 12 101 2.9E-26 T 09-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02810 15285f2ea348502f24f971f3589d7e8d 413 Gene3D G3DSA:3.40.640.10 58 288 1.5E-74 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS02810 15285f2ea348502f24f971f3589d7e8d 413 SUPERFAMILY SSF53383 17 410 2.15E-111 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS02810 15285f2ea348502f24f971f3589d7e8d 413 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 250 263 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_RS02810 15285f2ea348502f24f971f3589d7e8d 413 Pfam PF00155 Aminotransferase class I and II 46 399 1.2E-73 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS02810 15285f2ea348502f24f971f3589d7e8d 413 Gene3D G3DSA:3.90.1150.10 289 411 3.1E-35 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 SMART SM00738 80 188 1.5E-50 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 83 265 1.9E-65 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 Gene3D G3DSA:3.30.70.940 82 185 1.5E-42 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 ProSitePatterns PS01014 Transcription termination factor nusG signature. 248 257 - T 09-03-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 Pfam PF02357 Transcription termination factor nusG 82 184 8.9E-25 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 SUPERFAMILY SSF50104 209 265 4.21E-17 T 09-03-2017 IPR008991 Translation protein SH3-like domain UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 SUPERFAMILY SSF82679 82 185 1.02E-35 T 09-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 Gene3D G3DSA:2.30.30.30 204 265 5.1E-29 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 80 265 24.317 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 PRINTS PR00338 Transcription termination factor NUSG signature 241 257 4.9E-20 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 PRINTS PR00338 Transcription termination factor NUSG signature 135 147 4.9E-20 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_RS02825 1d55f00626da40bcd77a21ec408643a7 265 PRINTS PR00338 Transcription termination factor NUSG signature 223 238 4.9E-20 T 09-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:2.30.38.10 1011 1087 2.0E-25 T 09-03-2017 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF13193 AMP-binding enzyme C-terminal domain 1106 1181 4.8E-13 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF52777 429 662 4.56E-26 T 09-03-2017 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF00668 Condensation domain 53 277 3.1E-22 T 09-03-2017 IPR001242 Condensation domain UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF52777 153 254 1.89E-30 T 09-03-2017 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF52777 58 126 1.89E-30 T 09-03-2017 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 ProSitePatterns PS00455 Putative AMP-binding domain signature. 850 861 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.40.50.980 691 873 2.6E-46 T 09-03-2017 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:1.10.1200.10 1213 1278 1.6E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF47336 1202 1275 9.55E-18 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF00550 Phosphopantetheine attachment site 1211 1274 6.8E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF56801 678 1221 2.49E-150 T 09-03-2017 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF00501 AMP-binding enzyme 698 1098 6.9E-96 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.30.300.30 1094 1212 1.3E-34 T 09-03-2017 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SMART SM00823 Phosphopantetheine attachment site 1209 1278 2.2E-4 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 719 1122 2.9E-124 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS06585 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.40.50.980 876 1010 6.5E-36 T 09-03-2017 UA74_RS04920 a8147702b449e146434174b967a0d424 347 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 242 324 8.3E-11 T 09-03-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 UA74_RS04920 a8147702b449e146434174b967a0d424 347 Pfam PF13180 PDZ domain 143 206 4.3E-10 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04920 a8147702b449e146434174b967a0d424 347 SUPERFAMILY SSF50156 141 242 1.97E-15 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04920 a8147702b449e146434174b967a0d424 347 Gene3D G3DSA:2.30.42.10 143 214 2.7E-14 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04920 a8147702b449e146434174b967a0d424 347 SMART SM00228 88 199 1.0E-5 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04920 a8147702b449e146434174b967a0d424 347 SUPERFAMILY SSF54211 230 334 4.93E-20 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS04920 a8147702b449e146434174b967a0d424 347 Gene3D G3DSA:3.30.230.10 239 333 1.8E-21 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS09495 bc717e290842f1bb273263f1bf8841df 145 Gene3D G3DSA:1.25.40.10 107 143 5.1E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS21730 6f18aa18f2cd7ed0700b0fef802dc120 355 SUPERFAMILY SSF46589 31 115 3.92E-14 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 UA74_RS21730 6f18aa18f2cd7ed0700b0fef802dc120 355 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 103 6.8E-15 T 09-03-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UA74_RS21730 6f18aa18f2cd7ed0700b0fef802dc120 355 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 70 347 1.5E-84 T 09-03-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UA74_RS21730 6f18aa18f2cd7ed0700b0fef802dc120 355 Gene3D G3DSA:3.30.930.10 26 352 4.8E-112 T 09-03-2017 UA74_RS21730 6f18aa18f2cd7ed0700b0fef802dc120 355 SUPERFAMILY SSF55681 109 348 4.97E-73 T 09-03-2017 UA74_RS21730 6f18aa18f2cd7ed0700b0fef802dc120 355 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 351 43.767 T 09-03-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 UA74_RS21730 6f18aa18f2cd7ed0700b0fef802dc120 355 Pfam PF01409 tRNA synthetases class II core domain (F) 109 348 4.3E-96 T 09-03-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 238 4.3E-41 T 09-03-2017 UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 7.3E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 7.3E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 7.3E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.3E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 7.3E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 7.3E-29 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 Gene3D G3DSA:3.40.50.720 3 241 1.3E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 SUPERFAMILY SSF51735 3 241 1.57E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 183 0.004 T 09-03-2017 UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 9.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 9.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25805 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 9.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS28035 f9eec93cf2ece81e8e4723dadbc4e250 106 Gene3D G3DSA:3.40.50.1820 22 89 4.2E-9 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS28035 f9eec93cf2ece81e8e4723dadbc4e250 106 SUPERFAMILY SSF53474 23 89 6.13E-8 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 SUPERFAMILY SSF50615 14 97 8.37E-25 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 1.3E-14 T 09-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 09-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 SUPERFAMILY SSF52540 99 381 3.72E-93 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 Gene3D G3DSA:3.40.50.300 98 382 4.6E-106 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 Gene3D G3DSA:1.20.150.20 383 511 1.5E-50 T 09-03-2017 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 48.646 T 09-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 SUPERFAMILY SSF47917 383 511 1.54E-44 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 Gene3D G3DSA:2.40.30.20 5 96 1.2E-30 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 2.2E-67 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 2.6E-46 T 09-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07165 8d2a8b60473d6bc87cfe77899a7e0365 549 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 2.2E-243 T 09-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 392 478 3.0E-10 T 09-03-2017 IPR000160 GGDEF domain UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Gene3D G3DSA:3.30.70.270 395 493 1.9E-15 T 09-03-2017 UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Pfam PF00563 EAL domain 6 223 3.4E-35 T 09-03-2017 IPR001633 EAL domain UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SMART SM00267 381 543 3.6E-6 T 09-03-2017 IPR000160 GGDEF domain UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Gene3D G3DSA:3.20.20.450 7 224 2.9E-35 T 09-03-2017 IPR001633 EAL domain UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SMART SM00052 6 233 5.1E-11 T 09-03-2017 IPR001633 EAL domain UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SUPERFAMILY SSF54631 332 405 1.92E-6 T 09-03-2017 UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Gene3D G3DSA:3.10.580.10 268 384 3.1E-4 T 09-03-2017 UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SUPERFAMILY SSF55073 397 534 4.24E-15 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Pfam PF00990 Diguanylate cyclase, GGDEF domain 396 477 1.8E-10 T 09-03-2017 IPR000160 GGDEF domain UA74_RS12660 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SUPERFAMILY SSF141868 6 224 3.4E-37 T 09-03-2017 IPR001633 EAL domain UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 SUPERFAMILY SSF53901 2 256 3.93E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 Gene3D G3DSA:3.40.47.10 2 261 4.9E-67 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 SMART SM00825 Beta-ketoacyl synthase 5 407 1.0E-13 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 251 1.8E-49 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 Gene3D G3DSA:3.40.47.10 269 415 1.1E-52 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 SUPERFAMILY SSF53901 219 416 4.37E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11075 ffa924a8fa707e0531d800fd48508f1c 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 373 1.4E-34 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS25940 e04cc3c318f657c88fa93af5feaaffd5 77 Gene3D G3DSA:3.30.70.920 4 76 1.9E-16 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS25940 e04cc3c318f657c88fa93af5feaaffd5 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 75 1.6E-12 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS25940 e04cc3c318f657c88fa93af5feaaffd5 77 SUPERFAMILY SSF54909 2 76 3.75E-14 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 32 282 6.4E-43 T 09-03-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 Gene3D G3DSA:1.10.8.100 223 287 6.5E-20 T 09-03-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 60 87 - T 09-03-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 28 286 7.3E-75 T 09-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 SMART SM00650 44 218 2.6E-65 T 09-03-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 28 289 48.225 T 09-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 Gene3D G3DSA:3.40.50.150 16 219 5.9E-66 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS03465 e741935038d4d0e77a0859822565c08d 292 SUPERFAMILY SSF53335 28 286 1.75E-63 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 SUPERFAMILY SSF50993 6 423 1.26E-68 T 09-03-2017 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 SUPERFAMILY SSF53474 439 696 2.95E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 530 560 - T 09-03-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 Pfam PF00326 Prolyl oligopeptidase family 489 700 9.3E-53 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 608 623 1.3E-44 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 627 649 1.3E-44 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 469 487 1.3E-44 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 495 519 1.3E-44 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 523 542 1.3E-44 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 553 573 1.3E-44 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 9 411 5.9E-66 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 Gene3D G3DSA:3.40.50.1820 438 696 1.3E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08020 24ab639c1120194ee8ac3f548814d1ef 706 Gene3D G3DSA:2.130.10.120 77 428 8.6E-72 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_RS08550 fd0d4aa31e7563dec6e98d0dec50259d 167 Pfam PF11292 Protein of unknown function (DUF3093) 1 136 1.4E-45 T 09-03-2017 IPR021443 Protein of unknown function DUF3093 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 SUPERFAMILY SSF50494 207 375 9.24E-33 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 SUPERFAMILY SSF54806 140 189 4.97E-5 T 09-03-2017 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 Pfam PF02983 Alpha-lytic protease prodomain 123 179 3.1E-12 T 09-03-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 PIRSF PIRSF001134 2 384 1.0E-125 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:3.30.300.50 123 193 6.3E-13 T 09-03-2017 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:3.30.300.50 40 120 1.4E-28 T 09-03-2017 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:2.40.10.10 281 369 4.9E-30 T 09-03-2017 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:2.40.10.10 201 280 1.5E-24 T 09-03-2017 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 304 321 1.2E-42 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 346 1.2E-42 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 223 237 1.2E-42 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 347 361 1.2E-42 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01940 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 303 1.2E-42 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS03855 d8e9b884c4d1d63d9a54518083f8b000 266 Gene3D G3DSA:3.40.50.1110 34 225 1.6E-19 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS03855 d8e9b884c4d1d63d9a54518083f8b000 266 SUPERFAMILY SSF52266 33 226 1.17E-25 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS03855 d8e9b884c4d1d63d9a54518083f8b000 266 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 37 213 6.7E-16 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS05885 deadf68faa0918516aa9d842f349b1ba 408 Pfam PF08421 Putative zinc binding domain 7 66 8.1E-20 T 09-03-2017 IPR013630 Methyltransferase putative zinc binding domain UA74_RS05885 deadf68faa0918516aa9d842f349b1ba 408 Pfam PF13489 Methyltransferase domain 103 241 3.4E-19 T 09-03-2017 UA74_RS05885 deadf68faa0918516aa9d842f349b1ba 408 Pfam PF08484 C-methyltransferase C-terminal domain 247 403 3.5E-55 T 09-03-2017 IPR013691 C-methyltransferase UA74_RS05885 deadf68faa0918516aa9d842f349b1ba 408 Gene3D G3DSA:3.40.50.150 101 253 1.4E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05885 deadf68faa0918516aa9d842f349b1ba 408 SUPERFAMILY SSF53335 65 250 1.82E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.9E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.9E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.9E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.9E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 3.9E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.9E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 188 0.0085 T 09-03-2017 UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 Pfam PF00106 short chain dehydrogenase 3 187 3.6E-45 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 Gene3D G3DSA:3.40.50.720 2 243 7.2E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05580 cc58f3c5d2448a36df5e2c65785eb07c 276 SUPERFAMILY SSF51735 2 243 9.53E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Pfam PF02151 UvrB/uvrC motif 682 715 1.8E-6 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 SUPERFAMILY SSF46600 670 716 4.18E-10 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Pfam PF12344 Ultra-violet resistance protein B 581 622 3.0E-20 T 09-03-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 SUPERFAMILY SSF52540 63 112 7.36E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 SUPERFAMILY SSF52540 488 608 7.36E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.40.50.300 417 438 3.4E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.40.50.300 36 119 3.4E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.40.50.300 307 367 3.4E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Pfam PF04851 Type III restriction enzyme, res subunit 45 149 5.8E-8 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:4.10.860.10 669 717 5.4E-13 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 SUPERFAMILY SSF52540 35 444 3.17E-130 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 SMART SM00487 39 455 2.4E-24 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 34 713 0.0 T 09-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 SMART SM00490 489 575 3.2E-17 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Hamap MF_00204 UvrABC system protein B [uvrB]. 33 715 42.573 T 09-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.40.50.300 448 613 1.0E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.30.2060.10 191 259 4.4E-11 T 09-03-2017 UA74_RS10765 f4dadea4551594035f80170df0a36eca 725 Pfam PF00271 Helicase conserved C-terminal domain 465 574 8.8E-19 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 SMART SM00304 166 218 5.8E-9 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 Gene3D G3DSA:3.30.565.10 286 429 6.1E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 SUPERFAMILY SSF55874 284 429 6.36E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 SUPERFAMILY SSF158472 167 216 7.72E-5 T 09-03-2017 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 5.4E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 411 5.4E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 SMART SM00387 325 433 4.7E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 Gene3D G3DSA:1.10.287.130 210 268 7.2E-10 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 SMART SM00388 219 277 1.3E-4 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 273 4.0E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 Pfam PF00672 HAMP domain 146 214 8.5E-12 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS08865 3c79c5784a5b6b345d0df82f838c9749 434 SUPERFAMILY SSF47384 205 268 1.02E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS19860 1d5374fc4beeee4a2780ab0094fc36b9 173 SUPERFAMILY SSF88659 106 168 2.06E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS19860 1d5374fc4beeee4a2780ab0094fc36b9 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 168 4.5E-15 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS19860 1d5374fc4beeee4a2780ab0094fc36b9 173 Pfam PF04542 Sigma-70 region 2 16 80 1.7E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS19860 1d5374fc4beeee4a2780ab0094fc36b9 173 Gene3D G3DSA:1.10.10.10 108 168 5.7E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19860 1d5374fc4beeee4a2780ab0094fc36b9 173 Gene3D G3DSA:1.10.1740.10 6 81 5.3E-10 T 09-03-2017 UA74_RS19860 1d5374fc4beeee4a2780ab0094fc36b9 173 SUPERFAMILY SSF88946 6 91 1.41E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF50156 788 865 3.1E-9 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF07676 WD40-like Beta Propeller Repeat 45 64 6.3E-4 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF69304 373 525 5.62E-19 T 09-03-2017 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF69304 631 673 5.62E-19 T 09-03-2017 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:3.30.750.44 709 776 2.5E-29 T 09-03-2017 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 PIRSF PIRSF036421 1 1114 0.0 T 09-03-2017 IPR012393 Tricorn protease GO:0008236 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:3.90.226.10 905 1112 3.9E-36 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF14685 Tricorn protease PDZ domain 788 868 3.0E-26 T 09-03-2017 IPR029414 Tricorn protease, PDZ domain UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF69304 163 300 1.31E-28 T 09-03-2017 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF69304 5 136 1.31E-28 T 09-03-2017 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF52096 709 785 3.64E-65 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF52096 897 1106 3.64E-65 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF14684 Tricorn protease C1 domain 710 774 2.2E-27 T 09-03-2017 IPR028204 Tricorn protease C1 domain UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:2.130.10.10 5 107 7.2E-24 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:2.130.10.10 368 684 2.0E-72 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:2.130.10.10 263 333 2.0E-72 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:2.30.42.10 786 901 2.2E-24 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 SMART SM00245 888 1081 2.4E-16 T 09-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UA74_RS03715 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF03572 Peptidase family S41 924 1080 3.6E-21 T 09-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UA74_RS22405 edfabe5f6eff627e38c23f9987ab7c36 267 SUPERFAMILY SSF46785 15 88 3.5E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22405 edfabe5f6eff627e38c23f9987ab7c36 267 Pfam PF09339 IclR helix-turn-helix domain 17 65 7.4E-13 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS22405 edfabe5f6eff627e38c23f9987ab7c36 267 Gene3D G3DSA:1.10.10.10 14 86 2.1E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22405 edfabe5f6eff627e38c23f9987ab7c36 267 SMART SM00346 15 105 1.1E-21 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS22405 edfabe5f6eff627e38c23f9987ab7c36 267 SUPERFAMILY SSF55781 88 261 3.01E-33 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22405 edfabe5f6eff627e38c23f9987ab7c36 267 Gene3D G3DSA:3.30.450.40 87 263 4.0E-36 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22405 edfabe5f6eff627e38c23f9987ab7c36 267 Pfam PF01614 Bacterial transcriptional regulator 137 258 6.0E-15 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS01655 886670f7a5dc2d3420b423e4d979dd14 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 103 203 2.4E-10 T 09-03-2017 IPR023214 HAD-like domain UA74_RS01655 886670f7a5dc2d3420b423e4d979dd14 232 SUPERFAMILY SSF56784 4 210 3.16E-29 T 09-03-2017 IPR023214 HAD-like domain UA74_RS01655 886670f7a5dc2d3420b423e4d979dd14 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 9.4E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS01655 886670f7a5dc2d3420b423e4d979dd14 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 9.4E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS01655 886670f7a5dc2d3420b423e4d979dd14 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 9.4E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS01655 886670f7a5dc2d3420b423e4d979dd14 232 Gene3D G3DSA:3.40.50.1000 3 210 1.1E-30 T 09-03-2017 IPR023214 HAD-like domain UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Pfam PF14765 Polyketide synthase dehydratase 1106 1357 2.7E-12 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Gene3D G3DSA:3.40.47.10 27 322 3.0E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 599 838 2.6E-10 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 443 495 5.0E-8 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF52151 748 849 2.28E-23 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF52151 596 686 2.28E-23 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF53901 206 432 4.89E-75 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF53901 464 484 4.89E-75 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF53901 24 146 4.89E-75 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Gene3D G3DSA:3.40.47.10 323 485 2.1E-52 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 223 239 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Pfam PF00698 Acyl transferase domain 636 824 2.3E-14 T 09-03-2017 IPR014043 Acyl transferase UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Gene3D G3DSA:3.90.470.20 1397 1487 7.1E-11 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF56214 1399 1484 5.76E-10 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Gene3D G3DSA:3.90.470.20 1494 1577 2.1E-10 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Gene3D G3DSA:3.40.366.10 639 682 5.5E-22 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Gene3D G3DSA:3.40.366.10 746 856 5.5E-22 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 26 310 4.7E-57 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF56214 1493 1575 3.31E-13 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 318 436 4.5E-33 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SUPERFAMILY SSF55048 689 745 1.12E-5 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1493 1577 3.4E-10 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21895 7bc6fa704f1f7b4a5d92f1ec0e8df5d6 1654 SMART SM00825 Beta-ketoacyl synthase 27 488 3.9E-96 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 SUPERFAMILY SSF55424 338 409 2.06E-19 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 Gene3D G3DSA:3.30.390.30 342 409 7.1E-19 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 SUPERFAMILY SSF51905 4 188 5.0E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 6.1E-20 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 6.1E-20 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.1E-20 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 6.1E-20 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 6.1E-20 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 Gene3D G3DSA:3.50.50.60 106 243 1.4E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 Gene3D G3DSA:3.50.50.60 244 327 5.0E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 SUPERFAMILY SSF51905 144 323 4.59E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 315 1.5E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 Gene3D G3DSA:3.50.50.60 3 105 3.6E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 Pfam PF14759 Reductase C-terminal 342 410 1.9E-14 T 09-03-2017 IPR028202 Reductase, C-terminal UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.7E-15 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 4.7E-15 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 4.7E-15 T 09-03-2017 UA74_RS06670 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 4.7E-15 T 09-03-2017 UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 Gene3D G3DSA:1.10.1040.10 507 585 1.8E-10 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 Pfam PF00378 Enoyl-CoA hydratase/isomerase 38 220 6.3E-25 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 Gene3D G3DSA:3.90.226.10 20 219 1.5E-39 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 505 586 1.8E-11 T 09-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 501 2.0E-56 T 09-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 Gene3D G3DSA:3.40.50.720 317 506 5.7E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 SUPERFAMILY SSF52096 19 202 6.94E-39 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 SUPERFAMILY SSF52096 235 299 6.94E-39 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 SUPERFAMILY SSF48179 616 682 9.35E-11 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 SUPERFAMILY SSF48179 503 607 9.35E-15 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS23840 31e7a4507b596e2690caebdc367bdb1f 691 SUPERFAMILY SSF51735 319 503 6.18E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 Gene3D G3DSA:1.10.10.10 136 196 1.2E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 189 1.8E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.7E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.7E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.7E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 SMART SM00421 134 191 6.1E-25 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 Gene3D G3DSA:3.40.50.2300 3 135 2.2E-23 T 09-03-2017 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 Pfam PF00072 Response regulator receiver domain 4 115 1.5E-12 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 SMART SM00448 2 115 9.9E-7 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 SUPERFAMILY SSF52172 3 122 1.85E-16 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS28080 a09c3f1cc198baa3a2371798600cb34b 198 SUPERFAMILY SSF46894 125 197 1.94E-21 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS25100 b65a323384ff9cc3b86980570ce1f20d 286 Pfam PF13560 Helix-turn-helix domain 13 75 8.5E-15 T 09-03-2017 UA74_RS25100 b65a323384ff9cc3b86980570ce1f20d 286 SMART SM00530 17 72 2.9E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS25100 b65a323384ff9cc3b86980570ce1f20d 286 Gene3D G3DSA:1.10.260.40 13 68 9.6E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25100 b65a323384ff9cc3b86980570ce1f20d 286 SUPERFAMILY SSF47413 12 68 7.68E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS19310 24d39504f4ff96663269c5202e6a7f45 212 SUPERFAMILY SSF55166 83 192 1.31E-20 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS19310 24d39504f4ff96663269c5202e6a7f45 212 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 85 159 2.9E-11 T 09-03-2017 IPR003709 Peptidase M15B GO:0006508|GO:0008233 UA74_RS19310 24d39504f4ff96663269c5202e6a7f45 212 Gene3D G3DSA:3.30.1380.10 78 158 1.1E-6 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS15420 00f08312b1819b81bd05da1a32187397 503 SUPERFAMILY SSF103473 3 187 3.27E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15420 00f08312b1819b81bd05da1a32187397 503 SUPERFAMILY SSF103473 243 413 3.27E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15420 00f08312b1819b81bd05da1a32187397 503 SUPERFAMILY SSF103473 461 491 3.27E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15420 00f08312b1819b81bd05da1a32187397 503 Gene3D G3DSA:1.20.1250.20 4 184 2.7E-25 T 09-03-2017 UA74_RS15420 00f08312b1819b81bd05da1a32187397 503 Gene3D G3DSA:1.20.1250.20 258 414 6.0E-22 T 09-03-2017 UA74_RS15420 00f08312b1819b81bd05da1a32187397 503 Gene3D G3DSA:1.20.1250.20 462 488 6.0E-22 T 09-03-2017 UA74_RS15420 00f08312b1819b81bd05da1a32187397 503 Pfam PF07690 Major Facilitator Superfamily 13 402 1.3E-46 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS27340 73538c649b191fbe54fa7dd0864b866c 245 Pfam PF00005 ABC transporter 24 161 5.5E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS27340 73538c649b191fbe54fa7dd0864b866c 245 SUPERFAMILY SSF52540 4 222 9.52E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27340 73538c649b191fbe54fa7dd0864b866c 245 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS27340 73538c649b191fbe54fa7dd0864b866c 245 SMART SM00382 32 209 2.4E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS27340 73538c649b191fbe54fa7dd0864b866c 245 Gene3D G3DSA:3.40.50.300 4 223 7.7E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10130 315ec2ab37e0b69523249c809e23cc76 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 09-03-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS10130 315ec2ab37e0b69523249c809e23cc76 271 Gene3D G3DSA:3.20.20.70 3 265 4.9E-88 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS10130 315ec2ab37e0b69523249c809e23cc76 271 Pfam PF00290 Tryptophan synthase alpha chain 8 254 1.3E-68 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS10130 315ec2ab37e0b69523249c809e23cc76 271 SUPERFAMILY SSF51366 1 239 1.04E-76 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 UA74_RS10130 315ec2ab37e0b69523249c809e23cc76 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 262 31.237 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS10130 315ec2ab37e0b69523249c809e23cc76 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 242 2.7E-63 T 09-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:1.10.1200.10 2375 2447 2.1E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:1.10.1200.10 3848 3921 1.0E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:1.10.1200.10 921 976 3.8E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF53901 2468 2837 7.29E-100 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF55048 3114 3184 2.49E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1159 1175 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2993 3294 6.1E-116 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1521 1831 8.0E-112 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 539 839 4.2E-97 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2405 2420 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00550 Phosphopantetheine attachment site 914 973 5.3E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00550 Phosphopantetheine attachment site 3859 3918 4.4E-8 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00550 Phosphopantetheine attachment site 2387 2446 4.9E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2849 2953 1.5E-15 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 379 499 5.2E-13 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1374 1491 3.8E-16 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00825 Beta-ketoacyl synthase 2473 2899 7.0E-211 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00825 Beta-ketoacyl synthase 998 1424 2.7E-221 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00825 Beta-ketoacyl synthase 21 429 1.4E-188 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00823 Phosphopantetheine attachment site 907 977 5.8E-17 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00823 Phosphopantetheine attachment site 3851 3923 3.7E-25 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00823 Phosphopantetheine attachment site 2378 2450 2.8E-29 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.366.10 730 853 7.8E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.366.10 530 659 7.8E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF55048 1642 1718 1.02E-9 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF52151 2989 3115 6.02E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF52151 3185 3281 6.02E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF51735 3350 3554 2.41E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.47.10 2734 2901 1.2E-62 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.47.10 1259 1424 1.6E-63 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.47.10 265 429 6.9E-59 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF51735 1890 2087 6.69E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF47336 2373 2485 3.01E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 996 1246 1.3E-85 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 19 251 9.5E-78 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2471 2721 6.5E-86 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF53901 995 1370 2.58E-99 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF52151 1517 1643 1.83E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF52151 1719 1815 1.83E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF08659 KR domain 2098 2276 2.9E-53 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF08659 KR domain 3567 3743 1.9E-56 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.50.720 2098 2280 5.9E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.50.720 3567 3747 1.7E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00698 Acyl transferase domain 1520 1834 3.1E-79 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00698 Acyl transferase domain 2993 3299 2.4E-83 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF00698 Acyl transferase domain 537 857 4.7E-78 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2634 2650 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF51735 2096 2329 1.84E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2729 2846 1.2E-41 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 377 1.5E-39 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1254 1371 5.3E-43 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF55048 665 724 2.49E-9 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.30.70.250 664 722 2.0E-7 T 09-03-2017 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.30.70.250 1642 1717 5.7E-6 T 09-03-2017 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.30.70.250 3114 3183 2.8E-8 T 09-03-2017 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF47336 3843 3923 3.27E-16 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF52151 536 664 2.62E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF52151 731 825 2.62E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3567 3745 4.8E-44 T 09-03-2017 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2098 2278 1.0E-38 T 09-03-2017 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF53901 15 372 4.41E-86 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF53901 404 420 4.41E-86 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF47336 910 1010 2.49E-16 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SMART SM01294 2379 2446 1.4E-5 T 09-03-2017 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.47.10 2473 2733 1.0E-87 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.47.10 999 1258 5.4E-91 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.47.10 21 264 1.6E-84 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.366.10 1514 1637 6.3E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.366.10 3184 3297 3.0E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.366.10 1718 1834 6.3E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 Gene3D G3DSA:3.40.366.10 2987 3109 3.0E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16540 5b13df6f7c056ad3ea05242e3f95d8c6 4006 SUPERFAMILY SSF51735 3562 3803 4.12E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08930 53a1a86a45912ec25ae26d8b438207ae 79 Hamap MF_00088 UPF0109 protein . 4 75 20.446 T 09-03-2017 IPR020627 Uncharacterised protein family UPF0109 UA74_RS08930 53a1a86a45912ec25ae26d8b438207ae 79 SUPERFAMILY SSF54814 18 61 1.11E-7 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 UA74_RS08930 53a1a86a45912ec25ae26d8b438207ae 79 Pfam PF13083 KH domain 6 66 6.8E-19 T 09-03-2017 UA74_RS08930 53a1a86a45912ec25ae26d8b438207ae 79 Gene3D G3DSA:3.30.300.120 10 61 1.2E-5 T 09-03-2017 UA74_RS25310 76ceb380b5b7ad03cc6dedd84c7168d6 526 Gene3D G3DSA:3.40.50.1820 394 514 1.3E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25310 76ceb380b5b7ad03cc6dedd84c7168d6 526 Gene3D G3DSA:3.40.50.1820 80 166 1.3E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25310 76ceb380b5b7ad03cc6dedd84c7168d6 526 Gene3D G3DSA:3.40.50.1820 212 335 1.3E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25310 76ceb380b5b7ad03cc6dedd84c7168d6 526 SUPERFAMILY SSF53474 115 168 7.32E-19 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25310 76ceb380b5b7ad03cc6dedd84c7168d6 526 SUPERFAMILY SSF53474 369 509 7.32E-19 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25310 76ceb380b5b7ad03cc6dedd84c7168d6 526 SUPERFAMILY SSF53474 214 268 7.32E-19 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25310 76ceb380b5b7ad03cc6dedd84c7168d6 526 Pfam PF00561 alpha/beta hydrolase fold 115 502 7.3E-47 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS16610 087a5223da538d7277813f842e02921a 576 Pfam PF00664 ABC transporter transmembrane region 26 286 2.2E-21 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS16610 087a5223da538d7277813f842e02921a 576 SMART SM00382 354 540 6.4E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16610 087a5223da538d7277813f842e02921a 576 Gene3D G3DSA:1.20.1560.10 17 317 1.4E-36 T 09-03-2017 UA74_RS16610 087a5223da538d7277813f842e02921a 576 Pfam PF00005 ABC transporter 345 494 1.6E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16610 087a5223da538d7277813f842e02921a 576 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS16610 087a5223da538d7277813f842e02921a 576 SUPERFAMILY SSF90123 5 319 3.66E-43 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS16610 087a5223da538d7277813f842e02921a 576 SUPERFAMILY SSF52540 321 563 2.02E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16610 087a5223da538d7277813f842e02921a 576 Gene3D G3DSA:3.40.50.300 330 566 2.3E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 385 1.7E-50 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 Gene3D G3DSA:1.10.540.10 9 120 1.5E-34 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 SUPERFAMILY SSF56645 8 247 1.7E-75 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 Gene3D G3DSA:1.20.140.10 224 386 7.2E-70 T 09-03-2017 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 PIRSF PIRSF016578 6 387 3.3E-25 T 09-03-2017 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 120 2.0E-30 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 SUPERFAMILY SSF47203 233 386 5.64E-59 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 Gene3D G3DSA:2.40.110.10 126 223 2.1E-40 T 09-03-2017 UA74_RS26970 00755c3d9361566ab102c378ad52d0c1 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 2.7E-28 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 2692 2907 7.28E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF53901 29 400 4.08E-99 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 2107 2230 6.6E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 2300 2413 6.6E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 3584 3713 4.8E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 3782 3894 4.8E-71 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 753 866 4.6E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 558 682 4.6E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 562 688 1.75E-66 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 754 850 1.75E-66 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 1838 2004 1.2E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 3324 3486 9.0E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 297 461 6.2E-63 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM01294 4716 4783 2.7E-6 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM01294 1482 1549 3.5E-5 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM01294 2969 3036 3.2E-7 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 3587 3719 3.92E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 3783 3877 3.92E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 4436 4637 2.46E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:1.10.1200.10 1480 1553 4.3E-19 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:1.10.1200.10 4713 4787 1.1E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:1.10.1200.10 2967 3041 1.7E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 2110 2236 1.75E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 2301 2398 1.75E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3591 3892 3.8E-116 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2114 2411 3.6E-108 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 566 863 2.3E-116 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF55048 687 753 8.24E-13 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.30.70.250 2234 2299 1.4E-7 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.30.70.250 687 752 2.1E-8 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.30.70.250 3719 3781 3.7E-9 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1575 1825 5.5E-88 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.0E-86 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3061 3311 1.8E-87 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 529 3.1E-15 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1953 2053 4.6E-12 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3439 3556 3.4E-14 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3224 3240 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4742 4757 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 3063 3323 2.7E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 36 296 7.1E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 1577 1837 4.4E-87 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1508 1523 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1193 1373 1.1E-43 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2695 2872 5.1E-52 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4437 4617 8.6E-54 T 09-03-2017 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00823 Phosphopantetheine attachment site 4715 4787 4.1E-33 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00823 Phosphopantetheine attachment site 1481 1553 2.4E-27 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00823 Phosphopantetheine attachment site 2968 3040 1.3E-30 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF47336 2963 3076 2.22E-24 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1738 1754 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3319 3436 1.4E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1834 1950 2.4E-42 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 8.0E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF53901 3060 3427 2.14E-104 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08990 Erythronolide synthase docking 3 26 5.1E-11 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF47336 4708 4794 5.1E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00550 Phosphopantetheine attachment site 1483 1547 1.3E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00550 Phosphopantetheine attachment site 4721 4783 3.5E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00550 Phosphopantetheine attachment site 2970 3036 3.2E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF53901 1572 1941 3.7E-104 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08659 KR domain 1193 1371 7.7E-55 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08659 KR domain 2695 2870 9.3E-58 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08659 KR domain 4437 4616 5.2E-56 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2995 3010 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF47336 1480 1589 5.76E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF55048 3718 3782 3.66E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00826 3957 4121 7.9E-76 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 4239 4415 1.75E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF14765 Polyketide synthase dehydratase 3957 4230 2.8E-57 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 1188 1426 1.2E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00825 Beta-ketoacyl synthase 1577 2003 5.6E-216 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00825 Beta-ketoacyl synthase 36 462 7.4E-220 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00825 Beta-ketoacyl synthase 3063 3487 1.5E-218 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF55048 2235 2300 2.75E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 2476 2684 7.1E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00698 Acyl transferase domain 566 868 5.5E-85 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00698 Acyl transferase domain 2112 2426 1.2E-84 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00698 Acyl transferase domain 3590 3910 1.1E-49 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.50.720 2695 2899 2.2E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.50.720 4437 4634 6.9E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.50.720 1193 1414 1.1E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16530 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 970 1179 1.46E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11715 728baaf9187d357c1d918d817a5fa5f3 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS11715 728baaf9187d357c1d918d817a5fa5f3 489 Pfam PF00171 Aldehyde dehydrogenase family 21 485 4.7E-164 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS11715 728baaf9187d357c1d918d817a5fa5f3 489 Gene3D G3DSA:3.40.605.10 13 270 9.2E-94 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS11715 728baaf9187d357c1d918d817a5fa5f3 489 SUPERFAMILY SSF53720 11 487 7.33E-165 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS11715 728baaf9187d357c1d918d817a5fa5f3 489 Gene3D G3DSA:3.40.309.10 271 460 3.7E-66 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 Pfam PF06071 Protein of unknown function (DUF933) 275 358 7.8E-38 T 09-03-2017 IPR013029 Domain of unknown function DUF933 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 4.3E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.3E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.3E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 4.3E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 Gene3D G3DSA:3.40.50.300 4 130 7.9E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 Gene3D G3DSA:3.40.50.300 199 257 7.9E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 359 42.754 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 Gene3D G3DSA:3.10.20.30 258 359 2.9E-45 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 SUPERFAMILY SSF81271 275 359 2.62E-34 T 09-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 359 4.6E-132 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 SUPERFAMILY SSF52540 3 297 2.9E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 PIRSF PIRSF006641 1 359 1.2E-138 T 09-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 Gene3D G3DSA:1.10.150.300 131 198 4.2E-19 T 09-03-2017 IPR023192 TGS-like domain UA74_RS04230 b39bcc1674e7d63ccf5747803b74b680 359 Pfam PF01926 50S ribosome-binding GTPase 5 127 4.1E-21 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS05520 154518c35d7f7f722ff370afc038bc44 178 Gene3D G3DSA:3.30.1310.10 17 121 1.9E-12 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS05520 154518c35d7f7f722ff370afc038bc44 178 SUPERFAMILY SSF82607 34 117 4.05E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS05520 154518c35d7f7f722ff370afc038bc44 178 Pfam PF02575 YbaB/EbfC DNA-binding family 32 115 2.4E-11 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SUPERFAMILY SSF141259 517 597 3.92E-18 T 09-03-2017 IPR003711 CarD-like/TRCF domain UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Gene3D G3DSA:3.40.50.300 852 1005 7.8E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Pfam PF03461 TRCF domain 1061 1156 9.0E-18 T 09-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Pfam PF00270 DEAD/DEAH box helicase 674 815 1.3E-16 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 49 1171 28.106 T 09-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SMART SM00487 649 845 1.7E-27 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SUPERFAMILY SSF143517 1047 1221 1.57E-28 T 09-03-2017 UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SUPERFAMILY SSF52540 31 377 2.1E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SUPERFAMILY SSF52540 831 1038 2.66E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SMART SM01058 524 625 1.0E-46 T 09-03-2017 IPR003711 CarD-like/TRCF domain UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SMART SM00490 875 959 9.1E-18 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Gene3D G3DSA:3.30.2060.10 156 231 3.0E-14 T 09-03-2017 UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SMART SM00982 1060 1170 7.4E-33 T 09-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SUPERFAMILY SSF52540 575 832 2.12E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Pfam PF00271 Helicase conserved C-terminal domain 859 958 4.3E-15 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Pfam PF02559 CarD-like/TRCF domain 525 624 2.0E-30 T 09-03-2017 IPR003711 CarD-like/TRCF domain UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 173 1146 0.0 T 09-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 SUPERFAMILY SSF52540 403 511 6.64E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03685 5aa4749f29c7c4a828db6e579a741395 1234 Gene3D G3DSA:3.40.50.300 637 835 2.1E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09055 643cea9e1827d0eaffe1cfbcd50b005d 292 Pfam PF01148 Cytidylyltransferase family 33 287 4.5E-55 T 09-03-2017 UA74_RS09055 643cea9e1827d0eaffe1cfbcd50b005d 292 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 246 272 - T 09-03-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 UA74_RS00420 3c06b6dd8eefbacf6ffef9426db7f3f7 274 SUPERFAMILY SSF52172 9 144 5.27E-23 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS00420 3c06b6dd8eefbacf6ffef9426db7f3f7 274 SMART SM00448 10 134 3.3E-12 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS00420 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Gene3D G3DSA:2.40.50.40 155 222 9.7E-17 T 09-03-2017 UA74_RS00420 3c06b6dd8eefbacf6ffef9426db7f3f7 274 SMART SM00850 164 263 1.2E-28 T 09-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 UA74_RS00420 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Pfam PF00072 Response regulator receiver domain 12 134 1.5E-13 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS00420 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Gene3D G3DSA:3.40.50.2300 6 142 4.7E-22 T 09-03-2017 UA74_RS00420 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Pfam PF04397 LytTr DNA-binding domain 166 262 2.5E-23 T 09-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 UA74_RS18860 ced4168baf9949ca3966dd8eaeea5b0e 262 SMART SM00346 13 102 5.6E-18 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS18860 ced4168baf9949ca3966dd8eaeea5b0e 262 SUPERFAMILY SSF55781 78 253 1.57E-45 T 09-03-2017 IPR029016 GAF domain-like UA74_RS18860 ced4168baf9949ca3966dd8eaeea5b0e 262 Pfam PF09339 IclR helix-turn-helix domain 15 65 2.1E-14 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS18860 ced4168baf9949ca3966dd8eaeea5b0e 262 SUPERFAMILY SSF46785 13 85 6.12E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18860 ced4168baf9949ca3966dd8eaeea5b0e 262 Gene3D G3DSA:1.10.10.10 12 83 7.0E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18860 ced4168baf9949ca3966dd8eaeea5b0e 262 Pfam PF01614 Bacterial transcriptional regulator 130 251 2.1E-25 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS18860 ced4168baf9949ca3966dd8eaeea5b0e 262 Gene3D G3DSA:3.30.450.40 87 252 1.3E-49 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22235 73a721bd838d482a473ebf411b6fc70e 657 SUPERFAMILY SSF53850 105 638 1.3E-81 T 09-03-2017 UA74_RS22235 73a721bd838d482a473ebf411b6fc70e 657 Gene3D G3DSA:3.40.190.10 206 392 1.3E-20 T 09-03-2017 UA74_RS22235 73a721bd838d482a473ebf411b6fc70e 657 Gene3D G3DSA:3.10.105.10 393 611 8.4E-34 T 09-03-2017 UA74_RS22235 73a721bd838d482a473ebf411b6fc70e 657 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 124 532 2.8E-70 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS22235 73a721bd838d482a473ebf411b6fc70e 657 Gene3D G3DSA:3.90.76.10 112 205 6.1E-25 T 09-03-2017 UA74_RS09820 185860ab6ef69de3c74d8f306330703e 309 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 306 3.6E-84 T 09-03-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS09820 185860ab6ef69de3c74d8f306330703e 309 Pfam PF00849 RNA pseudouridylate synthase 91 244 5.3E-33 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS09820 185860ab6ef69de3c74d8f306330703e 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 09-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS09820 185860ab6ef69de3c74d8f306330703e 309 SUPERFAMILY SSF55120 77 306 2.24E-69 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS09820 185860ab6ef69de3c74d8f306330703e 309 Gene3D G3DSA:3.10.290.10 16 52 3.9E-4 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS22830 d60f3ef62d5ced6519b79e2521cbac78 436 Pfam PF14031 Putative serine dehydratase domain 325 418 3.5E-13 T 09-03-2017 IPR026956 D-serine dehydratase-like domain UA74_RS22830 d60f3ef62d5ced6519b79e2521cbac78 436 Pfam PF01168 Alanine racemase, N-terminal domain 60 267 2.9E-14 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS22830 d60f3ef62d5ced6519b79e2521cbac78 436 Gene3D G3DSA:3.20.20.10 61 228 1.8E-9 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS22830 d60f3ef62d5ced6519b79e2521cbac78 436 SUPERFAMILY SSF51419 61 303 1.05E-22 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS22830 d60f3ef62d5ced6519b79e2521cbac78 436 SMART SM01119 325 423 3.2E-24 T 09-03-2017 IPR026956 D-serine dehydratase-like domain UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 Gene3D G3DSA:3.50.50.60 273 351 4.4E-40 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 Gene3D G3DSA:3.50.50.60 9 175 4.4E-40 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 SUPERFAMILY SSF51905 12 170 8.83E-61 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 SUPERFAMILY SSF51905 272 374 8.83E-61 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.8E-21 T 09-03-2017 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 1.8E-21 T 09-03-2017 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.8E-21 T 09-03-2017 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 1.8E-21 T 09-03-2017 UA74_RS11135 7d59ae425a9eeeb7750d905eb67a2a2b 399 Pfam PF01494 FAD binding domain 12 347 1.5E-28 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS14825 bafa961c1a9f8d41c56556ebfc4a70ac 253 Gene3D G3DSA:3.40.50.300 27 147 2.2E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14825 bafa961c1a9f8d41c56556ebfc4a70ac 253 SUPERFAMILY SSF52540 27 163 4.48E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14825 bafa961c1a9f8d41c56556ebfc4a70ac 253 Pfam PF00265 Thymidine kinase 27 191 7.0E-20 T 09-03-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 UA74_RS08955 b69f426dbbb8ce1cddfe9693f5bdfea9 251 Hamap MF_00052_B Ribonuclease HII [rnhB]. 32 213 34.573 T 09-03-2017 IPR022898 Ribonuclease HII GO:0004523 UA74_RS08955 b69f426dbbb8ce1cddfe9693f5bdfea9 251 Gene3D G3DSA:3.30.420.10 33 173 1.2E-37 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS08955 b69f426dbbb8ce1cddfe9693f5bdfea9 251 SUPERFAMILY SSF53098 27 216 2.58E-58 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS08955 b69f426dbbb8ce1cddfe9693f5bdfea9 251 Pfam PF01351 Ribonuclease HII 34 213 4.8E-36 T 09-03-2017 IPR024567 Ribonuclease HII/HIII domain UA74_RS01470 d598d53332670bb2384a62816a33c445 172 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 31.785 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS01470 d598d53332670bb2384a62816a33c445 172 Gene3D G3DSA:3.90.80.10 2 156 6.1E-53 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS01470 d598d53332670bb2384a62816a33c445 172 SUPERFAMILY SSF50324 3 157 4.58E-55 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS01470 d598d53332670bb2384a62816a33c445 172 Pfam PF00719 Inorganic pyrophosphatase 5 156 2.3E-51 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS01470 d598d53332670bb2384a62816a33c445 172 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS08195 e3bb617357c403de70c0ec76c90d520a 302 Gene3D G3DSA:3.40.50.1820 69 301 1.8E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08195 e3bb617357c403de70c0ec76c90d520a 302 Pfam PF00756 Putative esterase 76 256 2.9E-7 T 09-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 UA74_RS08195 e3bb617357c403de70c0ec76c90d520a 302 SUPERFAMILY SSF53474 68 301 4.05E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19765 f548c98eea5c30ec9a34f6d6f1a3ca1e 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.7E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19765 f548c98eea5c30ec9a34f6d6f1a3ca1e 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.7E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19765 f548c98eea5c30ec9a34f6d6f1a3ca1e 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.7E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19765 f548c98eea5c30ec9a34f6d6f1a3ca1e 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 2.7E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19765 f548c98eea5c30ec9a34f6d6f1a3ca1e 262 Gene3D G3DSA:3.40.50.1820 11 262 8.2E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19765 f548c98eea5c30ec9a34f6d6f1a3ca1e 262 Pfam PF00561 alpha/beta hydrolase fold 25 126 1.0E-17 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19765 f548c98eea5c30ec9a34f6d6f1a3ca1e 262 SUPERFAMILY SSF53474 11 261 1.76E-58 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 SUPERFAMILY SSF47384 186 261 8.24E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 Gene3D G3DSA:3.30.565.10 270 405 1.9E-24 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 4.1E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 357 4.1E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 SMART SM00387 308 409 7.6E-17 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 Gene3D G3DSA:1.10.287.130 196 260 1.0E-6 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 SUPERFAMILY SSF55874 268 410 1.57E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 Pfam PF00672 HAMP domain 130 196 1.7E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 402 5.1E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS27015 6f89b36d6d1b00138a28e77e9411facc 425 SMART SM00388 202 266 0.002 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS03380 bf81f2ea81f264660be805e5cf2e1a59 29 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 28 6.0E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS03380 bf81f2ea81f264660be805e5cf2e1a59 29 Gene3D G3DSA:1.10.10.60 1 28 4.8E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS03380 bf81f2ea81f264660be805e5cf2e1a59 29 SUPERFAMILY SSF46689 1 28 9.48E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13110 702bc8e85bb8676dbb312b37a8fa4d84 166 Gene3D G3DSA:1.10.10.10 66 155 3.5E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13110 702bc8e85bb8676dbb312b37a8fa4d84 166 SUPERFAMILY SSF46894 65 153 1.5E-22 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS13110 702bc8e85bb8676dbb312b37a8fa4d84 166 Pfam PF00486 Transcriptional regulatory protein, C terminal 80 153 1.1E-21 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS13110 702bc8e85bb8676dbb312b37a8fa4d84 166 SMART SM00862 79 153 2.0E-23 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS08315 6116ebe642212de3459de69205bda507 480 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 09-03-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 333 5.6E-127 T 09-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 5.9E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 5.9E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 5.9E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 5.9E-34 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 Pfam PF01926 50S ribosome-binding GTPase 161 288 1.1E-21 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 SUPERFAMILY SSF82051 4 157 1.44E-48 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 Hamap MF_01454 GTPase Obg [obg]. 3 335 45.174 T 09-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 SUPERFAMILY SSF102741 367 433 5.89E-20 T 09-03-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 UA74_RS08315 6116ebe642212de3459de69205bda507 480 Pfam PF01018 GTP1/OBG 4 157 1.8E-54 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 UA74_RS08315 6116ebe642212de3459de69205bda507 480 Pfam PF09269 Domain of unknown function (DUF1967) 361 431 3.2E-24 T 09-03-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 UA74_RS08315 6116ebe642212de3459de69205bda507 480 Gene3D G3DSA:3.40.50.300 160 341 6.1E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08315 6116ebe642212de3459de69205bda507 480 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 369 432 6.3E-25 T 09-03-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 UA74_RS08315 6116ebe642212de3459de69205bda507 480 SUPERFAMILY SSF52540 161 346 1.68E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08315 6116ebe642212de3459de69205bda507 480 Gene3D G3DSA:2.70.210.12 3 156 3.5E-51 T 09-03-2017 IPR006169 GTP1/OBG domain GO:0005525 UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 SUPERFAMILY SSF53474 427 674 1.09E-64 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 Gene3D G3DSA:2.120.10.30 30 151 2.6E-24 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 Gene3D G3DSA:2.120.10.30 190 372 2.6E-24 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 SUPERFAMILY SSF82171 183 397 6.15E-26 T 09-03-2017 UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 SUPERFAMILY SSF82171 29 153 6.15E-26 T 09-03-2017 UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 Pfam PF00326 Prolyl oligopeptidase family 472 674 2.1E-45 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 Gene3D G3DSA:3.40.50.1820 426 674 6.5E-65 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08815 3a1fcbc2359a414a29c9f03fed08df24 687 Pfam PF07676 WD40-like Beta Propeller Repeat 72 108 4.7E-5 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS01195 c4526bcd498de3818c88ba204600ffa1 304 Gene3D G3DSA:3.40.50.720 7 181 3.0E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01195 c4526bcd498de3818c88ba204600ffa1 304 SUPERFAMILY SSF55347 167 255 5.67E-8 T 09-03-2017 UA74_RS01195 c4526bcd498de3818c88ba204600ffa1 304 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 123 2.6E-18 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS01195 c4526bcd498de3818c88ba204600ffa1 304 SUPERFAMILY SSF51735 8 142 4.24E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01195 c4526bcd498de3818c88ba204600ffa1 304 Gene3D G3DSA:3.30.360.10 182 302 1.4E-12 T 09-03-2017 UA74_RS13615 319729fadc0be9b816bbb575753e8bb7 292 Gene3D G3DSA:3.40.50.300 11 253 6.8E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13615 319729fadc0be9b816bbb575753e8bb7 292 SUPERFAMILY SSF52540 16 257 3.48E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13615 319729fadc0be9b816bbb575753e8bb7 292 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13615 319729fadc0be9b816bbb575753e8bb7 292 Pfam PF00005 ABC transporter 34 186 1.1E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13615 319729fadc0be9b816bbb575753e8bb7 292 SMART SM00382 42 234 1.0E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 SUPERFAMILY SSF56655 15 261 5.76E-63 T 09-03-2017 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 90 106 1.5E-36 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 220 244 1.5E-36 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 46 66 1.5E-36 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 1.5E-36 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 189 210 1.5E-36 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 68 84 1.5E-36 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 Gene3D G3DSA:3.30.540.10 13 157 3.2E-39 T 09-03-2017 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 Gene3D G3DSA:3.40.190.80 158 262 2.6E-26 T 09-03-2017 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 223 237 - T 09-03-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 UA74_RS01710 f5eb3b5e4620091a5ffcf44556ae628b 267 Pfam PF00459 Inositol monophosphatase family 17 258 3.3E-52 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Gene3D G3DSA:3.40.50.1240 191 397 6.3E-56 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 195 391 5.0E-57 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 SUPERFAMILY SSF53098 6 130 4.68E-31 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Pfam PF13456 Reverse transcriptase-like 11 132 3.7E-26 T 09-03-2017 UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 SMART SM00855 194 352 1.3E-19 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Gene3D G3DSA:3.30.420.10 5 136 2.0E-23 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 PIRSF PIRSF036922 2 397 2.6E-165 T 09-03-2017 IPR014636 RNase H, phosphoglycerate mutase domain-containing UA74_RS25410 6b43d1ee4cc28a0c20d801cdc69b76d7 397 SUPERFAMILY SSF53254 192 396 1.96E-53 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 SUPERFAMILY SSF55666 156 242 3.93E-22 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 09-03-2017 IPR018336 Ribonuclease PH, conserved site UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 Pfam PF03725 3' exoribonuclease family, domain 2 160 225 4.0E-10 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 Gene3D G3DSA:3.30.230.70 3 238 4.3E-28 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 SUPERFAMILY SSF54211 2 183 8.1E-41 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 Pfam PF01138 3' exoribonuclease family, domain 1 12 141 2.7E-20 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 238 4.8E-105 T 09-03-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 UA74_RS06345 280d3c4ca20d06e686c11d262dd573d8 252 Hamap MF_00564 Ribonuclease PH [rph]. 2 239 44.575 T 09-03-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF00550 Phosphopantetheine attachment site 1655 1720 2.2E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00823 Phosphopantetheine attachment site 1653 1724 5.6E-18 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF51735 1156 1350 2.51E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.47.10 3 266 9.3E-93 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF52151 526 650 2.43E-60 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF52151 713 809 2.43E-60 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00826 886 1037 6.9E-5 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1679 1694 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 167 183 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF51735 1364 1572 2.13E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.47.10 267 430 4.9E-62 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:1.10.1200.10 1651 1725 6.6E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF14765 Polyketide synthase dehydratase 886 1150 8.8E-18 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1366 1559 1.4E-53 T 09-03-2017 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00825 Beta-ketoacyl synthase 7 432 2.9E-200 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 529 822 1.2E-86 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF47336 1652 1726 4.06E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.50.720 1366 1579 2.0E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 382 494 6.6E-16 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 254 4.8E-83 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 379 3.7E-45 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.366.10 522 644 6.0E-61 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.366.10 711 826 6.0E-61 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF08659 KR domain 1366 1557 2.1E-59 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF55048 648 708 2.09E-7 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM01294 1654 1720 3.6E-5 T 09-03-2017 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF53901 2 375 4.01E-100 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17565 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF00698 Acyl transferase domain 527 833 3.7E-81 T 09-03-2017 IPR014043 Acyl transferase UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 SMART SM01217 781 851 2.4E-25 T 09-03-2017 IPR026891 Fibronectin type III-like domain UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:2.60.120.260 874 987 2.2E-11 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF50405 486 565 3.07E-7 T 09-03-2017 IPR008999 Actin cross-linking UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF52279 382 447 3.27E-49 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF52279 600 747 3.27E-49 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF51445 17 381 8.32E-71 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:2.80.10.50 477 572 2.5E-9 T 09-03-2017 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF49785 872 973 6.16E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:3.40.50.1700 368 447 9.3E-66 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:3.40.50.1700 600 747 9.3E-66 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 PRINTS PR00133 Glycosyl hydrolase family 3 signature 169 185 1.1E-7 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 PRINTS PR00133 Glycosyl hydrolase family 3 signature 80 99 1.1E-7 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Pfam PF14310 Fibronectin type III-like domain 781 851 8.1E-20 T 09-03-2017 IPR026891 Fibronectin type III-like domain UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:3.20.20.300 18 334 1.2E-78 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 382 744 7.4E-61 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS07430 bca070dde340ec8e99dae303bf89b2b5 1048 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 64 320 2.4E-37 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 SMART SM00478 63 210 7.4E-56 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 212 228 - T 09-03-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 SUPERFAMILY SSF48150 29 233 4.71E-63 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 TIGRFAM TIGR01083 nth: endonuclease III 30 219 3.9E-73 T 09-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 SMART SM00525 211 231 0.0017 T 09-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 Hamap MF_00942 Endonuclease III [nth]. 21 234 35.764 T 09-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 60 193 5.4E-19 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 Gene3D G3DSA:1.10.1670.10 148 231 3.5E-31 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 Gene3D G3DSA:1.10.340.30 47 147 1.1E-31 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 Pfam PF00633 Helix-hairpin-helix motif 124 151 5.2E-8 T 09-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 UA74_RS01235 be6d04165cb02c0b5e24b0d1f767b21b 258 ProSitePatterns PS01155 Endonuclease III family signature. 127 156 - T 09-03-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 Gene3D G3DSA:2.60.40.10 498 589 2.2E-30 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 123 134 5.4E-21 T 09-03-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 212 223 5.4E-21 T 09-03-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 299 311 5.4E-21 T 09-03-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 241 259 5.4E-21 T 09-03-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 91 108 5.4E-21 T 09-03-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 SMART SM00642 48 385 4.0E-74 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 Gene3D G3DSA:2.60.40.1180 392 479 5.7E-33 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 397 477 2.1E-15 T 09-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 SMART SM01065 495 587 1.1E-30 T 09-03-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 Pfam PF00128 Alpha amylase, catalytic domain 101 345 2.4E-19 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 SMART SM00632 394 480 3.3E-44 T 09-03-2017 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 Gene3D G3DSA:3.20.20.80 43 388 9.2E-99 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 Pfam PF00686 Starch binding domain 499 582 4.6E-29 T 09-03-2017 IPR002044 Carbohydrate binding module family 20 GO:2001070 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 SUPERFAMILY SSF51445 47 387 1.66E-78 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 SUPERFAMILY SSF49452 499 590 3.43E-31 T 09-03-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_RS18185 dad373118d02ce4af0ed7fb98a0f46ea 591 SUPERFAMILY SSF51011 391 479 7.71E-32 T 09-03-2017 UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 SMART SM00420 12 64 7.1E-11 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 Pfam PF08220 DeoR-like helix-turn-helix domain 12 67 6.0E-11 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 Pfam PF00455 DeoR C terminal sensor domain 83 238 1.6E-43 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 Gene3D G3DSA:3.40.50.1360 82 219 1.6E-9 T 09-03-2017 UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 SUPERFAMILY SSF46785 10 81 7.89E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 Gene3D G3DSA:1.10.10.10 8 65 2.4E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 SMART SM01134 79 240 1.2E-58 T 09-03-2017 UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS14350 5b38be69071c14b5b34e510b046621af 264 SUPERFAMILY SSF100950 82 239 1.67E-24 T 09-03-2017 UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Pfam PF04616 Glycosyl hydrolases family 43 189 475 2.8E-55 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 SUPERFAMILY SSF50370 41 178 4.19E-40 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 124 181 3.9E-12 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 45 118 1.2E-15 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Gene3D G3DSA:2.80.10.50 45 178 5.2E-29 T 09-03-2017 UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 SUPERFAMILY SSF75005 189 490 1.57E-59 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Gene3D G3DSA:2.115.10.20 184 492 4.0E-85 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS19895 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 SMART SM00458 44 178 7.7E-8 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS12460 c0f7a99434f3c8ff3ba0205df46c93cc 113 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 113 25.233 T 09-03-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_RS12460 c0f7a99434f3c8ff3ba0205df46c93cc 113 Pfam PF13397 RNA polymerase-binding protein 5 108 5.7E-42 T 09-03-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 SUPERFAMILY SSF54211 260 513 1.14E-95 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 Pfam PF00183 Hsp90 protein 194 661 8.5E-136 T 09-03-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 SUPERFAMILY SSF110942 541 659 2.62E-29 T 09-03-2017 UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 660 29.897 T 09-03-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 Gene3D G3DSA:3.30.565.10 253 267 1.4E-75 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 Gene3D G3DSA:3.30.565.10 6 218 1.4E-75 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 185 4.8E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PIRSF PIRSF002583 2 663 1.9E-212 T 09-03-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 SUPERFAMILY SSF55874 5 221 5.63E-60 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 SMART SM00387 28 187 3.4E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 6 26 1.0E-56 T 09-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 94 111 1.0E-56 T 09-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 76 93 1.0E-56 T 09-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 175 192 1.0E-56 T 09-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 27 49 1.0E-56 T 09-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 125 147 1.0E-56 T 09-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal UA74_RS17505 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 198 216 1.0E-56 T 09-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal UA74_RS06090 6f506590e93a37a695ba87540d9b0cde 581 Pfam PF10088 Uncharacterised protein conserved in bacteria (DUF2326) 446 581 3.1E-34 T 09-03-2017 IPR018760 Protein of unknown function DUF2326 UA74_RS06090 6f506590e93a37a695ba87540d9b0cde 581 Gene3D G3DSA:3.40.50.300 14 60 6.1E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20475 4b02010a5e1812cfad1372843c46cb3a 139 Gene3D G3DSA:3.10.180.10 14 133 7.8E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS20475 4b02010a5e1812cfad1372843c46cb3a 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 2.4E-13 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS20475 4b02010a5e1812cfad1372843c46cb3a 139 SUPERFAMILY SSF54593 8 133 1.14E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS09415 cbc093ace946838d2b357dfbf1139b1b 353 SUPERFAMILY SSF53098 134 271 1.52E-9 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS09415 cbc093ace946838d2b357dfbf1139b1b 353 Gene3D G3DSA:3.30.420.10 133 271 3.6E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS28170 18384d202d9519ee428fe3dd3d801d00 135 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 72 109 0.007 T 09-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 UA74_RS28170 18384d202d9519ee428fe3dd3d801d00 135 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 122 1.5E-22 T 09-03-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 UA74_RS28170 18384d202d9519ee428fe3dd3d801d00 135 SUPERFAMILY SSF56214 1 121 1.03E-25 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS28170 18384d202d9519ee428fe3dd3d801d00 135 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 21.156 T 09-03-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 UA74_RS28170 18384d202d9519ee428fe3dd3d801d00 135 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 121 7.0E-24 T 09-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 UA74_RS28170 18384d202d9519ee428fe3dd3d801d00 135 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 116 1.8E-16 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS28170 18384d202d9519ee428fe3dd3d801d00 135 Gene3D G3DSA:3.90.470.20 1 121 3.4E-38 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS29240 8a6680b101cdb00ab8c908b9f812d4a2 311 SMART SM00267 106 285 1.6E-41 T 09-03-2017 IPR000160 GGDEF domain UA74_RS29240 8a6680b101cdb00ab8c908b9f812d4a2 311 Gene3D G3DSA:3.30.70.270 119 287 1.9E-43 T 09-03-2017 UA74_RS29240 8a6680b101cdb00ab8c908b9f812d4a2 311 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 114 285 1.5E-39 T 09-03-2017 IPR000160 GGDEF domain UA74_RS29240 8a6680b101cdb00ab8c908b9f812d4a2 311 SUPERFAMILY SSF55073 122 286 2.59E-38 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS29240 8a6680b101cdb00ab8c908b9f812d4a2 311 Pfam PF00990 Diguanylate cyclase, GGDEF domain 118 280 6.4E-32 T 09-03-2017 IPR000160 GGDEF domain UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 Gene3D G3DSA:3.30.9.10 189 355 1.3E-47 T 09-03-2017 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 SUPERFAMILY SSF51905 22 194 1.98E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 SUPERFAMILY SSF51905 307 418 1.98E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 24 346 7.2E-73 T 09-03-2017 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 3.4E-14 T 09-03-2017 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 3.4E-14 T 09-03-2017 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 45 3.4E-14 T 09-03-2017 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 3.4E-14 T 09-03-2017 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 Pfam PF01494 FAD binding domain 22 340 2.5E-19 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS02535 1a76ac1e341d30d7fcd8271b58f9a5cc 441 Gene3D G3DSA:3.50.50.60 21 188 2.0E-19 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS29605 dfcce5f14f92b0c9afa55f7fada3efc5 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 1.7E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS29605 dfcce5f14f92b0c9afa55f7fada3efc5 180 SUPERFAMILY SSF46689 4 73 1.49E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS29605 dfcce5f14f92b0c9afa55f7fada3efc5 180 SUPERFAMILY SSF48498 79 178 1.11E-13 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS29605 dfcce5f14f92b0c9afa55f7fada3efc5 180 Gene3D G3DSA:1.10.357.10 4 178 2.2E-28 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS29605 dfcce5f14f92b0c9afa55f7fada3efc5 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 6.8E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS29605 dfcce5f14f92b0c9afa55f7fada3efc5 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 6.8E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 Gene3D G3DSA:3.40.50.720 3 125 3.5E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 4.8E-124 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 Gene3D G3DSA:3.40.50.261 126 290 6.1E-64 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 SMART SM00881 4 104 5.2E-33 T 09-03-2017 IPR003781 CoA-binding GO:0048037 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 SUPERFAMILY SSF52210 129 290 1.44E-44 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 PIRSF PIRSF001553 1 295 3.3E-115 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 Pfam PF00549 CoA-ligase 158 274 4.3E-13 T 09-03-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 5.0E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 5.0E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 5.0E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 5.0E-34 T 09-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 09-03-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 Pfam PF02629 CoA binding domain 7 103 1.3E-26 T 09-03-2017 IPR003781 CoA-binding GO:0048037 UA74_RS27855 5ae79bd611fb7f2eb2fe481123dea6e8 297 SUPERFAMILY SSF51735 1 128 1.17E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17390 cb78199f57d4d38f3bdde4cfcd8d402d 142 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 27 137 1.9E-30 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS17390 cb78199f57d4d38f3bdde4cfcd8d402d 142 Pfam PF04075 Domain of unknown function (DUF385) 16 135 1.3E-34 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS13410 7f2fc76a9555c6165c8f06266c4c8731 445 Pfam PF07602 Protein of unknown function (DUF1565) 87 126 3.5E-5 T 09-03-2017 IPR011459 Domain of unknown function DUF1565 UA74_RS13410 7f2fc76a9555c6165c8f06266c4c8731 445 SUPERFAMILY SSF51126 79 439 1.29E-60 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS13410 7f2fc76a9555c6165c8f06266c4c8731 445 Gene3D G3DSA:2.160.20.10 80 440 1.2E-75 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS13410 7f2fc76a9555c6165c8f06266c4c8731 445 Pfam PF13229 Right handed beta helix region 188 352 5.1E-10 T 09-03-2017 UA74_RS13945 782af4bd2939f73e506e40d543a499cb 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 22 176 7.2E-22 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS13945 782af4bd2939f73e506e40d543a499cb 469 Gene3D G3DSA:3.40.50.720 14 178 5.4E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13945 782af4bd2939f73e506e40d543a499cb 469 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 336 415 2.5E-12 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS13945 782af4bd2939f73e506e40d543a499cb 469 SUPERFAMILY SSF50475 336 467 9.82E-34 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS13945 782af4bd2939f73e506e40d543a499cb 469 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 336 465 1.4E-41 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS13945 782af4bd2939f73e506e40d543a499cb 469 Gene3D G3DSA:2.30.110.10 336 466 7.2E-27 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS13945 782af4bd2939f73e506e40d543a499cb 469 SUPERFAMILY SSF51735 22 176 6.9E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15415 b5b5dc145e6408f9e6c38b7617f8281d 416 Gene3D G3DSA:1.10.1740.10 6 96 1.2E-10 T 09-03-2017 UA74_RS15415 b5b5dc145e6408f9e6c38b7617f8281d 416 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 165 7.7E-14 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15415 b5b5dc145e6408f9e6c38b7617f8281d 416 Pfam PF08281 Sigma-70, region 4 114 165 3.4E-9 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15415 b5b5dc145e6408f9e6c38b7617f8281d 416 Gene3D G3DSA:1.10.10.10 108 165 1.0E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15415 b5b5dc145e6408f9e6c38b7617f8281d 416 Pfam PF04542 Sigma-70 region 2 10 76 6.5E-9 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15415 b5b5dc145e6408f9e6c38b7617f8281d 416 SUPERFAMILY SSF88659 107 165 1.07E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15415 b5b5dc145e6408f9e6c38b7617f8281d 416 SUPERFAMILY SSF88946 6 86 3.14E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00830 5ad02f6efeeb85855fc6f6d4c0d6540b 325 SUPERFAMILY SSF51735 4 168 3.72E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00830 5ad02f6efeeb85855fc6f6d4c0d6540b 325 Pfam PF02153 Prephenate dehydrogenase 28 243 1.9E-39 T 09-03-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 UA74_RS00830 5ad02f6efeeb85855fc6f6d4c0d6540b 325 Gene3D G3DSA:3.40.50.720 4 177 4.1E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00830 5ad02f6efeeb85855fc6f6d4c0d6540b 325 SUPERFAMILY SSF48179 172 269 4.65E-20 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 Pfam PF01965 DJ-1/PfpI family 44 181 2.9E-10 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 Pfam PF12833 Helix-turn-helix domain 244 321 2.0E-21 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 SUPERFAMILY SSF52317 12 204 3.93E-39 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 Gene3D G3DSA:1.10.10.60 230 275 7.8E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 SUPERFAMILY SSF46689 275 325 2.51E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 SMART SM00342 238 321 6.1E-26 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 Gene3D G3DSA:1.10.10.60 276 323 8.7E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 SUPERFAMILY SSF46689 227 272 1.36E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15645 ca4490eedf3898dff2acf9e212c381a1 331 Gene3D G3DSA:3.40.50.880 12 229 2.0E-44 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 20 476 4.4E-169 T 09-03-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 18 475 39.835 T 09-03-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 Gene3D G3DSA:2.160.10.10 280 461 1.2E-37 T 09-03-2017 UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 Pfam PF12804 MobA-like NTP transferase domain 22 167 6.3E-22 T 09-03-2017 IPR025877 MobA-like NTP transferase UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 Gene3D G3DSA:3.90.550.10 19 274 7.1E-75 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 418 451 0.0027 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 341 374 3.7E-4 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 SUPERFAMILY SSF51161 268 461 3.87E-36 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS03645 0842b6ff3bfb5aab07caa84992a5a1c0 507 SUPERFAMILY SSF53448 20 276 5.63E-60 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 460 1.8E-175 T 09-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Gene3D G3DSA:1.10.40.30 384 439 2.6E-27 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 1.1E-52 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 1.1E-52 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 1.1E-52 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 1.1E-52 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 1.1E-52 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 1.1E-52 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Pfam PF14698 Argininosuccinate lyase C-terminal 372 440 6.9E-22 T 09-03-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 1.2E-26 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 1.2E-26 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 1.2E-26 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 1.2E-26 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Gene3D G3DSA:1.20.200.10 116 383 3.0E-91 T 09-03-2017 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Pfam PF00206 Lyase 15 309 1.3E-59 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Hamap MF_00006 Argininosuccinate lyase [argH]. 10 462 38.99 T 09-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Gene3D G3DSA:1.10.275.10 10 115 1.0E-33 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal UA74_RS21660 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 SUPERFAMILY SSF48557 14 464 1.43E-129 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 UA74_RS25015 4c94241e55ebbdf23e73eb4fb55690e7 381 SUPERFAMILY SSF54001 256 367 4.9E-38 T 09-03-2017 UA74_RS25015 4c94241e55ebbdf23e73eb4fb55690e7 381 Gene3D G3DSA:3.90.1720.10 260 376 5.3E-41 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain UA74_RS25015 4c94241e55ebbdf23e73eb4fb55690e7 381 Pfam PF00877 NlpC/P60 family 277 367 6.3E-24 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain UA74_RS21700 6dabae294d002341da463af1920fb971 345 SUPERFAMILY SSF54427 205 316 3.0E-15 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS21700 6dabae294d002341da463af1920fb971 345 Gene3D G3DSA:1.10.1740.10 18 93 7.5E-26 T 09-03-2017 UA74_RS21700 6dabae294d002341da463af1920fb971 345 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 43 74 - T 09-03-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21700 6dabae294d002341da463af1920fb971 345 Gene3D G3DSA:1.10.10.10 133 192 9.4E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21700 6dabae294d002341da463af1920fb971 345 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 191 2.0E-22 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21700 6dabae294d002341da463af1920fb971 345 Pfam PF08281 Sigma-70, region 4 137 190 2.2E-13 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21700 6dabae294d002341da463af1920fb971 345 SUPERFAMILY SSF88659 105 193 5.05E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21700 6dabae294d002341da463af1920fb971 345 SUPERFAMILY SSF88946 17 91 4.71E-22 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21700 6dabae294d002341da463af1920fb971 345 Pfam PF04542 Sigma-70 region 2 22 88 6.0E-20 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21700 6dabae294d002341da463af1920fb971 345 Gene3D G3DSA:3.10.450.50 204 316 2.6E-18 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS21700 6dabae294d002341da463af1920fb971 345 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 18 324 8.0E-111 T 09-03-2017 IPR014305 RNA polymerase sigma-G type, actinobacteria UA74_RS21700 6dabae294d002341da463af1920fb971 345 Pfam PF12680 SnoaL-like domain 213 309 5.6E-7 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PIRSF PIRSF001480 1 424 1.7E-93 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:2.60.120.10 7 141 4.7E-59 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:2.60.120.10 247 282 4.7E-59 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 127 135 - T 09-03-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 5 397 1.2E-62 T 09-03-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 SUPERFAMILY SSF51182 4 398 2.13E-90 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 Pfam PF01238 Phosphomannose isomerase type I 4 302 1.0E-56 T 09-03-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 127 150 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 82 103 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 2.3E-62 T 09-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:1.10.441.10 283 295 4.4E-22 T 09-03-2017 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:1.10.441.10 142 240 4.4E-22 T 09-03-2017 UA74_RS26775 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:2.60.120.10 296 422 5.5E-10 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS22660 4de6d8f0d07a80659524f43b3daa73e3 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 80 2.3E-19 T 09-03-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_RS22660 4de6d8f0d07a80659524f43b3daa73e3 157 Gene3D G3DSA:1.20.1290.10 13 150 3.5E-47 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_RS22660 4de6d8f0d07a80659524f43b3daa73e3 157 SUPERFAMILY SSF69118 13 152 4.06E-39 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_RS22660 4de6d8f0d07a80659524f43b3daa73e3 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 95 3.5E-20 T 09-03-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_RS04455 23864528ada780b57224a38abc2c4671 337 Gene3D G3DSA:2.160.10.10 171 333 1.4E-31 T 09-03-2017 UA74_RS04455 23864528ada780b57224a38abc2c4671 337 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 130 169 3.3E-20 T 09-03-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 UA74_RS04455 23864528ada780b57224a38abc2c4671 337 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 12 334 43.684 T 09-03-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 UA74_RS04455 23864528ada780b57224a38abc2c4671 337 SUPERFAMILY SSF51161 100 316 2.49E-38 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS04455 23864528ada780b57224a38abc2c4671 337 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 251 283 1.2E-14 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS04455 23864528ada780b57224a38abc2c4671 337 Gene3D G3DSA:3.30.60.70 130 169 3.4E-8 T 09-03-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 UA74_RS04455 23864528ada780b57224a38abc2c4671 337 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 14 336 1.5E-151 T 09-03-2017 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 UA74_RS28255 6dcace5e08d3b63eb6614dec8babda58 358 SUPERFAMILY SSF140453 46 122 2.75E-6 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS28255 6dcace5e08d3b63eb6614dec8babda58 358 Gene3D G3DSA:1.10.287.1060 46 121 7.2E-6 T 09-03-2017 UA74_RS01620 381c556d4c07fbedcb0c9c5c2d684925 294 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 153 8.9E-16 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_RS01620 381c556d4c07fbedcb0c9c5c2d684925 294 SMART SM00478 40 192 2.3E-41 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_RS01620 381c556d4c07fbedcb0c9c5c2d684925 294 Gene3D G3DSA:1.10.340.30 22 123 1.2E-35 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS01620 381c556d4c07fbedcb0c9c5c2d684925 294 Pfam PF00633 Helix-hairpin-helix motif 101 129 8.4E-7 T 09-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 UA74_RS01620 381c556d4c07fbedcb0c9c5c2d684925 294 SUPERFAMILY SSF48150 9 219 3.3E-62 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS01620 381c556d4c07fbedcb0c9c5c2d684925 294 Gene3D G3DSA:1.10.1670.10 124 219 3.6E-33 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UA74_RS08095 6a8630885e489d113f2d01cff2dbbf7c 406 SUPERFAMILY SSF55729 9 299 2.08E-44 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS08095 6a8630885e489d113f2d01cff2dbbf7c 406 Gene3D G3DSA:3.30.1050.10 287 395 3.9E-22 T 09-03-2017 IPR003033 SCP2 sterol-binding domain UA74_RS08095 6a8630885e489d113f2d01cff2dbbf7c 406 SUPERFAMILY SSF55718 300 403 2.55E-21 T 09-03-2017 IPR003033 SCP2 sterol-binding domain UA74_RS08095 6a8630885e489d113f2d01cff2dbbf7c 406 Pfam PF13527 Acetyltransferase (GNAT) domain 8 132 1.2E-25 T 09-03-2017 UA74_RS08095 6a8630885e489d113f2d01cff2dbbf7c 406 Gene3D G3DSA:3.40.630.30 157 286 6.4E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS08095 6a8630885e489d113f2d01cff2dbbf7c 406 Gene3D G3DSA:3.40.630.30 4 134 8.9E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS08095 6a8630885e489d113f2d01cff2dbbf7c 406 Pfam PF13530 Sterol carrier protein domain 181 402 7.2E-44 T 09-03-2017 IPR025559 Enhanced intracellular survival protein domain UA74_RS25890 7bea361682b1f5024904cc4e3cf8cfee 632 SMART SM01120 35 201 1.5E-45 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS25890 7bea361682b1f5024904cc4e3cf8cfee 632 Pfam PF13684 Dihydroxyacetone kinase family 312 632 6.0E-71 T 09-03-2017 IPR033470 Uncharacterised protein, DhaK domain UA74_RS25890 7bea361682b1f5024904cc4e3cf8cfee 632 Pfam PF02734 DAK2 domain 35 200 1.2E-32 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS25890 7bea361682b1f5024904cc4e3cf8cfee 632 SMART SM01121 310 632 2.1E-71 T 09-03-2017 IPR033470 Uncharacterised protein, DhaK domain UA74_RS25890 7bea361682b1f5024904cc4e3cf8cfee 632 SUPERFAMILY SSF101473 5 202 7.32E-34 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 ProSitePatterns PS00211 ABC transporters family signature. 526 540 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF00005 ABC transporter 53 218 3.6E-20 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF00005 ABC transporter 398 553 1.1E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 Gene3D G3DSA:3.40.50.300 366 629 2.8E-79 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 Gene3D G3DSA:3.40.50.300 31 293 2.4E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 SUPERFAMILY SSF52540 32 290 1.17E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 SMART SM00382 61 268 2.4E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 SMART SM00382 406 603 1.8E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 605 637 8.1E-7 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 270 300 0.0082 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 ProSitePatterns PS00211 ABC transporters family signature. 191 205 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS22220 149651ebc22e7acf90253411b7b38cf4 654 SUPERFAMILY SSF52540 390 625 9.27E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02530 c2e2f115d4b25d7a7b80c0233953c1c3 229 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 226 7.0E-64 T 09-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_RS02530 c2e2f115d4b25d7a7b80c0233953c1c3 229 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 32.453 T 09-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_RS02530 c2e2f115d4b25d7a7b80c0233953c1c3 229 Gene3D G3DSA:3.40.50.150 12 223 6.5E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS02530 c2e2f115d4b25d7a7b80c0233953c1c3 229 SUPERFAMILY SSF53335 7 224 3.41E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS02530 c2e2f115d4b25d7a7b80c0233953c1c3 229 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 226 3.7E-53 T 09-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_RS02530 c2e2f115d4b25d7a7b80c0233953c1c3 229 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 09-03-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UA74_RS20220 ee3f7333b91697d1e025ec2c18c58020 317 SUPERFAMILY SSF161098 91 297 3.92E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20220 ee3f7333b91697d1e025ec2c18c58020 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 4.6E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20220 ee3f7333b91697d1e025ec2c18c58020 317 Gene3D G3DSA:1.10.3720.10 90 308 6.0E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Gene3D G3DSA:3.40.710.10 335 562 1.2E-57 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Gene3D G3DSA:3.40.710.10 187 283 1.0E-7 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 182 335 1.7E-23 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 336 556 2.6E-49 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 444 458 1.0E-21 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 206 225 1.0E-21 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 429 443 1.0E-21 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 372 394 1.0E-21 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 340 540 1.1E-40 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS01480 988b72a63ec3e4d3d7fbb4b552d93d0d 563 SUPERFAMILY SSF56601 184 561 3.98E-57 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 Pfam PF07729 FCD domain 99 219 3.0E-20 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 SUPERFAMILY SSF46785 26 91 9.64E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 SMART SM00345 30 88 2.8E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 85 2.8E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 Gene3D G3DSA:1.20.120.530 93 222 1.7E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 SUPERFAMILY SSF48008 95 222 8.11E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 SMART SM00895 99 220 2.2E-18 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS10260 8898e45e32b59c0de631d5d267468e8e 236 Gene3D G3DSA:1.10.10.10 16 87 8.2E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00775 51af4147f5fcf53eeed6449d9ef785ba 98 SUPERFAMILY SSF89360 1 87 3.34E-8 T 09-03-2017 IPR000361 FeS cluster biogenesis UA74_RS00775 51af4147f5fcf53eeed6449d9ef785ba 98 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 78 7.8E-6 T 09-03-2017 IPR000361 FeS cluster biogenesis UA74_RS00775 51af4147f5fcf53eeed6449d9ef785ba 98 Gene3D G3DSA:2.60.300.12 1 84 3.5E-9 T 09-03-2017 IPR000361 FeS cluster biogenesis UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 663 766 4.81E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 552 690 5.12E-25 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF52540 58 325 1.72E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Gene3D G3DSA:1.25.40.10 795 926 6.2E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Gene3D G3DSA:1.25.40.10 458 575 5.0E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13424 Tetratricopeptide repeat 510 581 1.2E-11 T 09-03-2017 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13424 Tetratricopeptide repeat 629 692 4.8E-11 T 09-03-2017 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13424 Tetratricopeptide repeat 710 766 4.9E-9 T 09-03-2017 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 806 916 3.8E-14 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 PRINTS PR00364 Disease resistance protein signature 89 104 3.8E-8 T 09-03-2017 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 PRINTS PR00364 Disease resistance protein signature 174 188 3.8E-8 T 09-03-2017 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 PRINTS PR00364 Disease resistance protein signature 264 278 3.8E-8 T 09-03-2017 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 509 542 15.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 886 919 110.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 589 622 1.9 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 846 879 0.13 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 549 582 3.3 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 709 742 1.1 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 669 702 9.9 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 629 662 0.3 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 806 839 140.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13374 Tetratricopeptide repeat 591 622 1.9E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Gene3D G3DSA:1.25.40.10 576 761 3.3E-32 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 473 581 6.96E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03170 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF00931 NB-ARC domain 88 294 6.0E-9 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 SUPERFAMILY SSF56059 109 267 5.53E-44 T 09-03-2017 UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 SUPERFAMILY SSF56059 302 344 5.53E-44 T 09-03-2017 UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 Gene3D G3DSA:3.40.50.20 10 118 3.2E-27 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 SUPERFAMILY SSF52440 9 105 5.9E-23 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 SUPERFAMILY SSF51246 350 428 2.98E-17 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 Pfam PF02222 ATP-grasp domain 303 324 2.3E-7 T 09-03-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 Pfam PF02222 ATP-grasp domain 119 267 2.8E-37 T 09-03-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 406 39.171 T 09-03-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 Gene3D G3DSA:3.30.470.20 299 428 2.6E-80 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS26985 fc2335f91d6426eccecb65cf86a663fe 437 Gene3D G3DSA:3.30.470.20 150 264 2.6E-80 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS14990 7f3708ed5946c00beed9c04a0179500a 168 Gene3D G3DSA:2.30.110.10 21 168 1.1E-39 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS14990 7f3708ed5946c00beed9c04a0179500a 168 SUPERFAMILY SSF50475 23 155 3.44E-25 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS14990 7f3708ed5946c00beed9c04a0179500a 168 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 107 2.5E-14 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS18960 4a055725f8b4e69166e7d94faa3591cb 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 283 2.2E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18960 4a055725f8b4e69166e7d94faa3591cb 298 Gene3D G3DSA:1.10.3720.10 10 282 1.3E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18960 4a055725f8b4e69166e7d94faa3591cb 298 SUPERFAMILY SSF161098 54 280 5.23E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03885 e0a5717d3c950a0d3b11075a1ec919ac 361 SUPERFAMILY SSF50129 15 195 1.19E-39 T 09-03-2017 IPR011032 GroES-like UA74_RS03885 e0a5717d3c950a0d3b11075a1ec919ac 361 SUPERFAMILY SSF51735 164 325 2.27E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03885 e0a5717d3c950a0d3b11075a1ec919ac 361 Gene3D G3DSA:3.40.50.720 191 322 3.5E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03885 e0a5717d3c950a0d3b11075a1ec919ac 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 78 92 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS03885 e0a5717d3c950a0d3b11075a1ec919ac 361 Gene3D G3DSA:3.90.180.10 12 190 4.7E-43 T 09-03-2017 IPR011032 GroES-like UA74_RS03885 e0a5717d3c950a0d3b11075a1ec919ac 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 150 1.6E-26 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS03885 e0a5717d3c950a0d3b11075a1ec919ac 361 Pfam PF00107 Zinc-binding dehydrogenase 198 319 1.9E-15 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 17 416 1.8E-111 T 09-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 PIRSF PIRSF001235 12 422 2.2E-125 T 09-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 Pfam PF01546 Peptidase family M20/M25/M40 87 415 2.7E-29 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 Gene3D G3DSA:3.30.70.360 235 339 6.3E-29 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 SUPERFAMILY SSF53187 15 232 1.6E-78 T 09-03-2017 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 SUPERFAMILY SSF53187 346 420 1.6E-78 T 09-03-2017 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 Gene3D G3DSA:3.40.630.10 361 420 5.6E-96 T 09-03-2017 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 Gene3D G3DSA:3.40.630.10 15 234 5.6E-96 T 09-03-2017 UA74_RS24115 b29a3da01b90752b30c474f150ce6a3e 434 SUPERFAMILY SSF55031 222 339 1.06E-22 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 SUPERFAMILY SSF52096 302 559 2.42E-76 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Gene3D G3DSA:3.90.226.10 18 268 3.7E-66 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 305 391 9.9E-32 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Pfam PF01039 Carboxyl transferase domain 90 234 4.1E-17 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 224 235 6.7E-34 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 158 176 6.7E-34 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 124 138 6.7E-34 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 246 255 6.7E-34 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 195 212 6.7E-34 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 SUPERFAMILY SSF52096 21 269 2.08E-72 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 6 272 1.5E-95 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 2 276 34.497 T 09-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Gene3D G3DSA:3.90.226.10 306 513 4.7E-40 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS11115 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 253 560 37.283 T 09-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 Pfam PF07732 Multicopper oxidase 87 143 3.1E-10 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 Pfam PF07732 Multicopper oxidase 178 219 3.8E-4 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 Pfam PF07731 Multicopper oxidase 419 527 1.5E-19 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 SUPERFAMILY SSF49503 409 527 7.08E-27 T 09-03-2017 IPR008972 Cupredoxin UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 ProSitePatterns PS00080 Multicopper oxidases signature 2. 510 521 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 SUPERFAMILY SSF49503 223 359 2.9E-22 T 09-03-2017 IPR008972 Cupredoxin UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 Gene3D G3DSA:2.60.40.420 60 221 1.0E-25 T 09-03-2017 IPR008972 Cupredoxin UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 Gene3D G3DSA:2.60.40.420 222 379 4.6E-33 T 09-03-2017 IPR008972 Cupredoxin UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 SUPERFAMILY SSF49503 51 221 1.31E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS10940 3bae143c78c89372669e05e827af92cc 528 Gene3D G3DSA:2.60.40.420 380 527 2.4E-30 T 09-03-2017 IPR008972 Cupredoxin UA74_RS22415 ceea03abfec385e360e66328b2b801e1 445 Gene3D G3DSA:3.40.50.1820 1 264 9.7E-54 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22415 ceea03abfec385e360e66328b2b801e1 445 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 368 425 9.0E-16 T 09-03-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal UA74_RS22415 ceea03abfec385e360e66328b2b801e1 445 SUPERFAMILY SSF53474 1 263 4.36E-53 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22415 ceea03abfec385e360e66328b2b801e1 445 Pfam PF12697 Alpha/beta hydrolase family 26 256 1.6E-20 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22415 ceea03abfec385e360e66328b2b801e1 445 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 333 366 9.0E-9 T 09-03-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal UA74_RS22415 ceea03abfec385e360e66328b2b801e1 445 SUPERFAMILY SSF50249 320 432 7.2E-26 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 SUPERFAMILY SSF46911 7 80 2.09E-25 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 TIGRFAM TIGR00165 S18: ribosomal protein bS18 14 77 6.5E-24 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 Pfam PF01084 Ribosomal protein S18 25 75 1.3E-23 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 11 80 19.63 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 5.5E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 5.5E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 5.5E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 5.5E-18 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 Gene3D G3DSA:4.10.640.10 15 80 7.5E-28 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21230 0fb803d9bfb7093501153241fd5f472b 83 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 77 5.0E-17 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 Gene3D G3DSA:3.40.50.980 2 160 3.4E-32 T 09-03-2017 UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 Gene3D G3DSA:3.30.300.30 403 497 1.8E-24 T 09-03-2017 UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 Gene3D G3DSA:3.40.50.980 161 312 2.7E-34 T 09-03-2017 UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 SUPERFAMILY SSF56801 2 497 2.62E-105 T 09-03-2017 UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 Gene3D G3DSA:2.30.38.10 341 401 5.7E-8 T 09-03-2017 UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 Pfam PF00501 AMP-binding enzyme 9 408 5.2E-62 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS05280 0f83cd7119e020d3a0cd8446653bcaaa 498 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 489 1.5E-5 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS02990 a7d09a24a5e1e09a76c09ea30bd222ec 191 SUPERFAMILY SSF55282 10 185 2.12E-70 T 09-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02990 a7d09a24a5e1e09a76c09ea30bd222ec 191 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.015 T 09-03-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02990 a7d09a24a5e1e09a76c09ea30bd222ec 191 Pfam PF00673 ribosomal L5P family C-terminus 91 184 6.9E-37 T 09-03-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02990 a7d09a24a5e1e09a76c09ea30bd222ec 191 Gene3D G3DSA:3.30.1440.10 9 185 3.2E-70 T 09-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02990 a7d09a24a5e1e09a76c09ea30bd222ec 191 PIRSF PIRSF002161 5 191 4.1E-60 T 09-03-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02990 a7d09a24a5e1e09a76c09ea30bd222ec 191 Pfam PF00281 Ribosomal protein L5 31 87 2.1E-25 T 09-03-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS22780 57819ac238136f16a9f2cd4f99115615 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS22780 57819ac238136f16a9f2cd4f99115615 329 Gene3D G3DSA:3.40.50.720 113 294 1.1E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22780 57819ac238136f16a9f2cd4f99115615 329 SUPERFAMILY SSF52283 1 128 4.89E-18 T 09-03-2017 UA74_RS22780 57819ac238136f16a9f2cd4f99115615 329 Gene3D G3DSA:3.40.50.720 1 112 6.1E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22780 57819ac238136f16a9f2cd4f99115615 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 293 6.6E-48 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS22780 57819ac238136f16a9f2cd4f99115615 329 SUPERFAMILY SSF51735 97 294 1.06E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22780 57819ac238136f16a9f2cd4f99115615 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 325 1.9E-13 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:1.10.10.470 517 604 1.3E-20 T 09-03-2017 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 SMART SM00642 4 668 2.4E-6 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Pfam PF00128 Alpha amylase, catalytic domain 25 98 4.2E-13 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:3.30.1590.10 94 219 3.8E-34 T 09-03-2017 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 SUPERFAMILY SSF51445 3 699 2.19E-120 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:1.10.150.200 343 442 3.5E-6 T 09-03-2017 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 785 9.0E-253 T 09-03-2017 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:3.20.20.80 4 93 1.1E-67 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:3.20.20.80 608 726 1.1E-67 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:3.20.20.80 233 307 1.1E-67 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS21305 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:3.20.20.80 476 516 1.1E-67 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 Pfam PF00958 GMP synthase C terminal domain 431 523 2.4E-38 T 09-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 195 7.0E-70 T 09-03-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00097 Anthranilate synthase component II signature 169 182 1.3E-5 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00097 Anthranilate synthase component II signature 80 91 1.3E-5 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00097 Anthranilate synthase component II signature 53 62 1.3E-5 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 1.8E-6 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 1.8E-6 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 1.8E-6 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 2.9E-8 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 2.9E-8 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 2.9E-8 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 Pfam PF00117 Glutamine amidotransferase class-I 11 191 2.4E-39 T 09-03-2017 IPR017926 Glutamine amidotransferase UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 SUPERFAMILY SSF52317 6 229 1.99E-52 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 Gene3D G3DSA:3.40.50.880 9 214 2.1E-57 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 524 6.8E-145 T 09-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 SUPERFAMILY SSF54810 403 524 2.75E-46 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 Gene3D G3DSA:3.40.50.620 215 397 2.2E-56 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 SUPERFAMILY SSF52402 185 444 2.09E-57 T 09-03-2017 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 Pfam PF02540 NAD synthase 217 287 3.7E-5 T 09-03-2017 IPR022310 NAD/GMP synthase UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 524 53.095 T 09-03-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 UA74_RS28015 77e7cb38db8fa6edf9e697241c388d4e 524 Gene3D G3DSA:3.30.300.10 399 524 1.2E-48 T 09-03-2017 UA74_RS08555 de9aae04909f6ec2fb6f4fe61f7f756f 167 Pfam PF00692 dUTPase 16 148 7.9E-27 T 09-03-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 UA74_RS08555 de9aae04909f6ec2fb6f4fe61f7f756f 167 Gene3D G3DSA:2.70.40.10 4 148 1.3E-49 T 09-03-2017 IPR029054 dUTPase-like UA74_RS08555 de9aae04909f6ec2fb6f4fe61f7f756f 167 TIGRFAM TIGR00576 dut: dUTP diphosphatase 7 148 1.6E-45 T 09-03-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 UA74_RS08555 de9aae04909f6ec2fb6f4fe61f7f756f 167 SUPERFAMILY SSF51283 4 148 1.96E-42 T 09-03-2017 IPR029054 dUTPase-like UA74_RS08555 de9aae04909f6ec2fb6f4fe61f7f756f 167 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 4 149 29.722 T 09-03-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 UA74_RS04970 436030ef311a38d2ae5cd69609433c94 158 SUPERFAMILY SSF74982 4 133 1.7E-51 T 09-03-2017 IPR023620 Small protein B UA74_RS04970 436030ef311a38d2ae5cd69609433c94 158 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 7.6E-57 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 UA74_RS04970 436030ef311a38d2ae5cd69609433c94 158 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 131 1.0E-47 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 UA74_RS04970 436030ef311a38d2ae5cd69609433c94 158 Gene3D G3DSA:2.40.280.10 8 128 1.3E-49 T 09-03-2017 IPR023620 Small protein B UA74_RS04970 436030ef311a38d2ae5cd69609433c94 158 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 71.383 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 UA74_RS04970 436030ef311a38d2ae5cd69609433c94 158 Pfam PF01668 SmpB protein 9 72 1.5E-27 T 09-03-2017 IPR000037 SsrA-binding protein GO:0003723 UA74_RS04970 436030ef311a38d2ae5cd69609433c94 158 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 09-03-2017 IPR020081 SsrA-binding protein, conserved site UA74_RS27595 c72b06909cbfd27f6bbe45a6f5b385c4 324 SUPERFAMILY SSF46785 2 57 3.21E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27595 c72b06909cbfd27f6bbe45a6f5b385c4 324 Gene3D G3DSA:1.10.10.10 1 61 3.6E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27595 c72b06909cbfd27f6bbe45a6f5b385c4 324 Pfam PF13280 WYL domain 146 316 3.9E-30 T 09-03-2017 IPR026881 WYL domain UA74_RS27595 c72b06909cbfd27f6bbe45a6f5b385c4 324 Pfam PF08279 HTH domain 10 57 3.0E-14 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS04310 c714af154009a51faca3ac0b8101d703 524 Gene3D G3DSA:1.10.3720.10 259 513 6.6E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04310 c714af154009a51faca3ac0b8101d703 524 Gene3D G3DSA:1.10.3720.10 8 239 6.2E-37 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04310 c714af154009a51faca3ac0b8101d703 524 SUPERFAMILY SSF161098 5 230 2.22E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04310 c714af154009a51faca3ac0b8101d703 524 SUPERFAMILY SSF161098 255 512 1.2E-40 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04310 c714af154009a51faca3ac0b8101d703 524 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 231 3.6E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04310 c714af154009a51faca3ac0b8101d703 524 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 333 505 1.2E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08065 82d94433ceda07950ec367aee36fc188 274 Gene3D G3DSA:3.60.15.10 13 241 2.2E-43 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS08065 82d94433ceda07950ec367aee36fc188 274 SUPERFAMILY SSF56281 13 253 1.62E-40 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS08065 82d94433ceda07950ec367aee36fc188 274 Pfam PF00753 Metallo-beta-lactamase superfamily 32 220 2.5E-14 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS08065 82d94433ceda07950ec367aee36fc188 274 SMART SM00849 29 220 1.1E-19 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS07230 f913551ed09c2948d40815f1430a6281 271 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 19 268 1.2E-111 T 09-03-2017 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein UA74_RS07230 f913551ed09c2948d40815f1430a6281 271 SMART SM00382 43 241 8.5E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07230 f913551ed09c2948d40815f1430a6281 271 Pfam PF00005 ABC transporter 34 192 5.4E-35 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS07230 f913551ed09c2948d40815f1430a6281 271 PIRSF PIRSF039085 15 269 7.8E-98 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UA74_RS07230 f913551ed09c2948d40815f1430a6281 271 Gene3D G3DSA:3.40.50.300 18 266 8.7E-83 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07230 f913551ed09c2948d40815f1430a6281 271 SUPERFAMILY SSF52540 19 263 1.85E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07230 f913551ed09c2948d40815f1430a6281 271 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 Pfam PF13167 GTP-binding GTPase N-terminal 66 154 1.7E-34 T 09-03-2017 IPR025121 GTPase HflX, N-terminal UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 PIRSF PIRSF006809 41 471 4.4E-154 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 315 333 9.1E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 268 9.1E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 50 410 8.0E-131 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 Hamap MF_00900 GTPase HflX [hflX]. 69 440 47.171 T 09-03-2017 IPR016496 GTPase HflX GO:0005525 UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 Pfam PF01926 50S ribosome-binding GTPase 248 370 1.5E-18 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 SUPERFAMILY SSF52540 246 421 1.66E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 Gene3D G3DSA:3.40.50.300 246 413 1.6E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08725 0ab8ed5e62765016c1fbea07680e43e9 473 Pfam PF16360 GTP-binding GTPase Middle Region 156 240 1.2E-29 T 09-03-2017 IPR032305 GTP-binding protein, middle domain UA74_RS28720 0fe74ec60f10fae5658ad995bd74ff16 389 SMART SM00220 4 265 1.3E-48 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS28720 0fe74ec60f10fae5658ad995bd74ff16 389 Gene3D G3DSA:1.10.510.10 70 258 2.0E-41 T 09-03-2017 UA74_RS28720 0fe74ec60f10fae5658ad995bd74ff16 389 SUPERFAMILY SSF56112 2 306 1.78E-61 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS28720 0fe74ec60f10fae5658ad995bd74ff16 389 Gene3D G3DSA:3.30.200.20 2 69 1.2E-20 T 09-03-2017 UA74_RS28720 0fe74ec60f10fae5658ad995bd74ff16 389 Pfam PF00069 Protein kinase domain 4 252 5.4E-39 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS28720 0fe74ec60f10fae5658ad995bd74ff16 389 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 122 134 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS08175 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 5.4E-40 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08175 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 5.4E-40 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08175 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 5.4E-40 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08175 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 5.4E-40 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08175 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 5.4E-40 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08175 19f9286f154bc904027c588a0634266a 208 SUPERFAMILY SSF52096 20 204 2.31E-62 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS08175 19f9286f154bc904027c588a0634266a 208 Pfam PF00574 Clp protease 27 201 9.6E-74 T 09-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UA74_RS08175 19f9286f154bc904027c588a0634266a 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 09-03-2017 IPR033135 ClpP, histidine active site UA74_RS08175 19f9286f154bc904027c588a0634266a 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 38.533 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08175 19f9286f154bc904027c588a0634266a 208 Gene3D G3DSA:3.90.226.10 13 201 9.2E-74 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS08175 19f9286f154bc904027c588a0634266a 208 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 09-03-2017 IPR018215 ClpP, Ser active site UA74_RS09855 c6e0bac01b935462f80619d7366bd24d 265 SMART SM00530 15 88 8.1E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS09855 c6e0bac01b935462f80619d7366bd24d 265 Gene3D G3DSA:1.10.260.40 10 87 2.8E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09855 c6e0bac01b935462f80619d7366bd24d 265 Pfam PF13560 Helix-turn-helix domain 12 91 5.6E-16 T 09-03-2017 UA74_RS09855 c6e0bac01b935462f80619d7366bd24d 265 SUPERFAMILY SSF47413 36 86 2.67E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28485 d3ac7b187573f0ebef8de302302267f7 411 SUPERFAMILY SSF103473 23 404 5.62E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS28485 d3ac7b187573f0ebef8de302302267f7 411 Pfam PF05977 Transmembrane secretion effector 15 404 8.0E-56 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS28485 d3ac7b187573f0ebef8de302302267f7 411 Gene3D G3DSA:1.20.1250.20 37 209 1.0E-17 T 09-03-2017 UA74_RS28485 d3ac7b187573f0ebef8de302302267f7 411 Gene3D G3DSA:1.20.1250.20 231 405 3.9E-15 T 09-03-2017 UA74_RS16690 54b5bbb6f550b7809797f6946c8d42a8 329 PIRSF PIRSF016838 2 322 8.7E-27 T 09-03-2017 IPR028349 Protein PafC UA74_RS16690 54b5bbb6f550b7809797f6946c8d42a8 329 SUPERFAMILY SSF46785 6 62 1.44E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16690 54b5bbb6f550b7809797f6946c8d42a8 329 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS16690 54b5bbb6f550b7809797f6946c8d42a8 329 Pfam PF08279 HTH domain 7 58 2.1E-12 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS16690 54b5bbb6f550b7809797f6946c8d42a8 329 Pfam PF13280 WYL domain 143 311 1.4E-29 T 09-03-2017 IPR026881 WYL domain UA74_RS16690 54b5bbb6f550b7809797f6946c8d42a8 329 Gene3D G3DSA:1.10.10.10 3 64 1.3E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15885 03c7872bd99bf212b1f4a7eef2122162 383 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 233 362 3.1E-14 T 09-03-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain UA74_RS15885 03c7872bd99bf212b1f4a7eef2122162 383 Gene3D G3DSA:1.10.540.10 18 110 4.7E-17 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS15885 03c7872bd99bf212b1f4a7eef2122162 383 Gene3D G3DSA:1.20.140.10 202 376 1.4E-23 T 09-03-2017 UA74_RS15885 03c7872bd99bf212b1f4a7eef2122162 383 Gene3D G3DSA:2.40.110.10 119 201 7.4E-12 T 09-03-2017 UA74_RS15885 03c7872bd99bf212b1f4a7eef2122162 383 PIRSF PIRSF016578 2 380 1.1E-59 T 09-03-2017 UA74_RS15885 03c7872bd99bf212b1f4a7eef2122162 383 SUPERFAMILY SSF47203 229 360 9.33E-8 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS15885 03c7872bd99bf212b1f4a7eef2122162 383 SUPERFAMILY SSF56645 21 200 4.73E-18 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 Pfam PF13377 Periplasmic binding protein-like domain 189 336 5.6E-21 T 09-03-2017 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 SUPERFAMILY SSF47413 17 70 9.21E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 Gene3D G3DSA:3.40.50.2300 196 326 6.5E-19 T 09-03-2017 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 18 63 2.1E-11 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 Gene3D G3DSA:3.40.50.2300 69 195 1.0E-23 T 09-03-2017 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 Gene3D G3DSA:1.10.260.40 17 68 2.2E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 SMART SM00354 13 86 5.5E-12 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS16975 5b010d2dc4253388801eb29262285d8e 355 SUPERFAMILY SSF53822 86 335 4.32E-27 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS26900 8b8c003f16978ff167162ad47597cea8 478 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 79 248 6.8E-33 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS26900 8b8c003f16978ff167162ad47597cea8 478 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 79 247 1.8E-37 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS26900 8b8c003f16978ff167162ad47597cea8 478 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 353 436 1.6E-15 T 09-03-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_RS16090 9b42eb5d376788edfac4506963420d96 260 SUPERFAMILY SSF56752 12 242 2.75E-39 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 UA74_RS16090 9b42eb5d376788edfac4506963420d96 260 Gene3D G3DSA:3.30.470.10 22 106 1.4E-7 T 09-03-2017 UA74_RS16090 9b42eb5d376788edfac4506963420d96 260 Pfam PF01063 Amino-transferase class IV 23 233 6.8E-33 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 UA74_RS16090 9b42eb5d376788edfac4506963420d96 260 Gene3D G3DSA:3.20.10.10 115 256 1.1E-19 T 09-03-2017 UA74_RS03230 143740f4ff296c0d6dbfedf94e417018 166 SUPERFAMILY SSF53218 10 159 1.2E-34 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03230 143740f4ff296c0d6dbfedf94e417018 166 Pfam PF00994 Probable molybdopterin binding domain 13 154 6.9E-26 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03230 143740f4ff296c0d6dbfedf94e417018 166 Gene3D G3DSA:3.40.980.10 10 160 4.3E-41 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03230 143740f4ff296c0d6dbfedf94e417018 166 SMART SM00852 12 156 2.4E-17 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03230 143740f4ff296c0d6dbfedf94e417018 166 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 10 149 7.5E-28 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.30.470.20 209 449 8.7E-84 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.90.226.10 1518 1824 2.6E-52 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF01039 Carboxyl transferase domain 1334 1822 1.5E-29 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF52440 2 118 6.14E-32 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.30.1490.20 135 206 8.2E-25 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF52096 1295 1500 1.53E-21 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.40.50.20 2 134 9.5E-36 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF52096 1551 1824 5.68E-36 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF51246 335 450 1.36E-34 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:2.40.50.100 585 656 2.8E-15 T 09-03-2017 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF02785 Biotin carboxylase C-terminal domain 340 449 1.2E-34 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 328 1.3E-63 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF51230 581 656 1.7E-14 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.90.226.10 1262 1459 4.7E-20 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 115 3.3E-33 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF00364 Biotin-requiring enzyme 591 653 3.7E-7 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF56059 88 332 5.05E-60 T 09-03-2017 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 SMART SM00878 340 448 5.1E-48 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS15490 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF08326 Acetyl-CoA carboxylase, central region 1016 1208 2.3E-14 T 09-03-2017 IPR013537 Acetyl-CoA carboxylase, central domain GO:0003989|GO:0005524|GO:0006633 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-163765|Reactome: R-HSA-196780|Reactome: R-HSA-200425|Reactome: R-HSA-2426168|Reactome: R-HSA-3371599 UA74_RS21155 77b11d61ad7f1f608fac1532ea1736d4 247 SUPERFAMILY SSF69593 14 205 1.83E-35 T 09-03-2017 UA74_RS21155 77b11d61ad7f1f608fac1532ea1736d4 247 Pfam PF01553 Acyltransferase 23 149 5.7E-29 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS21155 77b11d61ad7f1f608fac1532ea1736d4 247 SMART SM00563 38 152 1.5E-33 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS21155 77b11d61ad7f1f608fac1532ea1736d4 247 Gene3D G3DSA:3.40.1130.10 28 189 4.5E-20 T 09-03-2017 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 252 5.1E-21 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 09-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 44.543 T 09-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 1.1E-39 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF53738 4 179 1.84E-45 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 365 6.8E-32 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.40.120.10 3 151 2.6E-44 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.30.310.50 368 442 1.4E-18 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.40.120.10 174 248 3.9E-28 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 439 3.7E-14 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 1.3E-13 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.3E-13 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.3E-13 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF53738 158 254 9.03E-29 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF55957 356 442 2.35E-22 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF53738 256 362 6.67E-29 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 7.3E-181 T 09-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS28210 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.40.120.10 249 366 9.5E-33 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS17745 2c61909fa918ecb1224d14a3566fcde6 210 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 24 206 1.8E-13 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS17745 2c61909fa918ecb1224d14a3566fcde6 210 Gene3D G3DSA:3.30.70.1210 94 205 8.7E-16 T 09-03-2017 UA74_RS17745 2c61909fa918ecb1224d14a3566fcde6 210 SUPERFAMILY SSF117987 3 79 7.85E-11 T 09-03-2017 UA74_RS17745 2c61909fa918ecb1224d14a3566fcde6 210 Gene3D G3DSA:3.30.70.1200 2 84 1.3E-13 T 09-03-2017 UA74_RS17745 2c61909fa918ecb1224d14a3566fcde6 210 SMART SM01101 2 206 1.7E-39 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS17745 2c61909fa918ecb1224d14a3566fcde6 210 Pfam PF08798 CRISPR associated protein 3 206 1.9E-39 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS17745 2c61909fa918ecb1224d14a3566fcde6 210 SUPERFAMILY SSF117987 94 206 4.97E-20 T 09-03-2017 UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 SMART SM00938 4 105 6.0E-42 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 Gene3D G3DSA:3.30.70.120 2 112 1.0E-35 T 09-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 SUPERFAMILY SSF54913 2 112 3.5E-34 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.3E-32 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 09-03-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 83 103 6.4E-30 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 2 17 6.4E-30 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 52 75 6.4E-30 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_RS25650 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 23 41 6.4E-30 T 09-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_RS20445 7958d8e973e40cd0f8ef91c3078ecc7a 493 Gene3D G3DSA:3.90.1200.10 300 431 3.4E-14 T 09-03-2017 UA74_RS20445 7958d8e973e40cd0f8ef91c3078ecc7a 493 SUPERFAMILY SSF56112 332 413 5.25E-26 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS20445 7958d8e973e40cd0f8ef91c3078ecc7a 493 SUPERFAMILY SSF56112 97 266 5.25E-26 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS20445 7958d8e973e40cd0f8ef91c3078ecc7a 493 Pfam PF01636 Phosphotransferase enzyme family 126 394 1.4E-11 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS26310 f923aefb4efcc26d12f0c67258914b4a 338 SUPERFAMILY SSF100939 1 256 7.65E-52 T 09-03-2017 IPR016194 SPOC-like, C-terminal domain UA74_RS26310 f923aefb4efcc26d12f0c67258914b4a 338 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 255 3.2E-88 T 09-03-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UA74_RS26310 f923aefb4efcc26d12f0c67258914b4a 338 PIRSF PIRSF006493 1 302 9.5E-91 T 09-03-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UA74_RS26310 f923aefb4efcc26d12f0c67258914b4a 338 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 253 33.613 T 09-03-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UA74_RS26310 f923aefb4efcc26d12f0c67258914b4a 338 SMART SM00559 52 180 1.0E-31 T 09-03-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 UA74_RS26310 f923aefb4efcc26d12f0c67258914b4a 338 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 187 1.1E-34 T 09-03-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 UA74_RS26310 f923aefb4efcc26d12f0c67258914b4a 338 Gene3D G3DSA:2.40.290.10 4 150 4.2E-8 T 09-03-2017 IPR016194 SPOC-like, C-terminal domain UA74_RS15640 41aa3f5537f57046b80ec1991d5a00db 414 Pfam PF00589 Phage integrase family 332 401 6.8E-7 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15640 41aa3f5537f57046b80ec1991d5a00db 414 SUPERFAMILY SSF47823 58 164 1.35E-25 T 09-03-2017 IPR010998 Integrase, Lambda-type, N-terminal UA74_RS15640 41aa3f5537f57046b80ec1991d5a00db 414 Gene3D G3DSA:1.10.150.130 60 166 3.8E-27 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS15640 41aa3f5537f57046b80ec1991d5a00db 414 SUPERFAMILY SSF56349 168 279 1.35E-30 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS15640 41aa3f5537f57046b80ec1991d5a00db 414 SUPERFAMILY SSF56349 320 411 1.35E-30 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS15640 41aa3f5537f57046b80ec1991d5a00db 414 Gene3D G3DSA:1.10.443.10 169 284 7.3E-45 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15640 41aa3f5537f57046b80ec1991d5a00db 414 Gene3D G3DSA:1.10.443.10 320 401 7.3E-45 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 SUPERFAMILY SSF53335 2 358 1.81E-77 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 62 74 - T 09-03-2017 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 Gene3D G3DSA:3.90.120.10 264 347 1.5E-21 T 09-03-2017 UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 Gene3D G3DSA:3.90.120.10 153 208 1.5E-21 T 09-03-2017 UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 Gene3D G3DSA:3.40.50.150 1 152 5.6E-49 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 100 114 9.9E-6 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 146 159 9.9E-6 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 163 4.5E-45 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 Pfam PF00145 C-5 cytosine-specific DNA methylase 306 358 5.7E-8 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14065 379643cb3397c8672ea8ec256adc4aab 363 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 1 160 5.5E-43 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS25645 85e99d041d632f37a03fa30863338170 342 Pfam PF05239 PRC-barrel domain 5 72 3.0E-8 T 09-03-2017 IPR027275 PRC-barrel domain UA74_RS25645 85e99d041d632f37a03fa30863338170 342 Pfam PF09557 Domain of unknown function (DUF2382) 211 322 6.8E-26 T 09-03-2017 IPR019060 Domain of unknown function DUF2382 UA74_RS25645 85e99d041d632f37a03fa30863338170 342 Gene3D G3DSA:3.90.50.10 9 100 4.4E-8 T 09-03-2017 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 UA74_RS25645 85e99d041d632f37a03fa30863338170 342 SUPERFAMILY SSF50346 4 106 1.24E-19 T 09-03-2017 IPR011033 PRC-barrel-like UA74_RS28180 e381677f4ecca35e3e51517d6fe6ffac 276 Gene3D G3DSA:3.40.50.1820 42 246 4.2E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS28180 e381677f4ecca35e3e51517d6fe6ffac 276 SUPERFAMILY SSF53474 15 242 2.63E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS28180 e381677f4ecca35e3e51517d6fe6ffac 276 Pfam PF12740 Chlorophyllase enzyme 31 148 1.6E-7 T 09-03-2017 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 Pfam PF09363 XFP C-terminal domain 591 792 6.0E-89 T 09-03-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 ProSitePatterns PS60003 Phosphoketolase signature 2. 161 179 - T 09-03-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 SUPERFAMILY SSF52518 380 594 9.57E-27 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 Gene3D G3DSA:3.40.50.970 12 369 8.3E-19 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 403 580 1.8E-87 T 09-03-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 ProSitePatterns PS60002 Phosphoketolase signature 1. 148 154 - T 09-03-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 Hamap MF_01403 Probable phosphoketolase. 9 794 40.336 T 09-03-2017 IPR023962 Probable phosphoketolase UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 SUPERFAMILY SSF52518 12 373 3.71E-70 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 PIRSF PIRSF017245 3 794 0.0 T 09-03-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 UA74_RS08120 bdaf01a406e00211f6756354b4dd360d 799 Pfam PF09364 XFP N-terminal domain 12 388 3.3E-179 T 09-03-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal UA74_RS00295 1b6eb54e8310f9f8b3fc89a394d48f64 486 Pfam PF01757 Acyltransferase family 117 437 3.8E-21 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Pfam PF00881 Nitroreductase family 258 426 3.2E-24 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 15 447 49.668 T 09-03-2017 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Gene3D G3DSA:3.40.109.10 253 442 6.0E-37 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 SUPERFAMILY SSF144010 11 244 5.1E-64 T 09-03-2017 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 SUPERFAMILY SSF55469 252 445 7.85E-36 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 253 445 4.0E-93 T 09-03-2017 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Pfam PF01996 F420-0:Gamma-glutamyl ligase 74 217 9.8E-33 T 09-03-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Pfam PF01996 F420-0:Gamma-glutamyl ligase 18 63 1.3E-6 T 09-03-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 10 240 3.7E-77 T 09-03-2017 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Gene3D G3DSA:3.30.1330.100 9 57 3.2E-53 T 09-03-2017 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Gene3D G3DSA:3.30.1330.100 132 220 3.2E-53 T 09-03-2017 UA74_RS26820 ead04aaf37dca318f552d2c50fda425b 447 Gene3D G3DSA:3.90.1660.10 65 131 5.2E-19 T 09-03-2017 UA74_RS03665 c896423e830374965abf799714b88249 199 SUPERFAMILY SSF46689 3 76 3.28E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS03665 c896423e830374965abf799714b88249 199 SUPERFAMILY SSF48498 77 186 2.08E-10 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS03665 c896423e830374965abf799714b88249 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 6.7E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS03665 c896423e830374965abf799714b88249 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 6.7E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS03665 c896423e830374965abf799714b88249 199 Gene3D G3DSA:1.10.357.10 2 185 1.7E-44 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS03665 c896423e830374965abf799714b88249 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS03665 c896423e830374965abf799714b88249 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 4.6E-17 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS08450 f6177db4b49f1616b29a465f00a53722 222 Pfam PF01553 Acyltransferase 20 150 3.2E-26 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS08450 f6177db4b49f1616b29a465f00a53722 222 SUPERFAMILY SSF69593 5 218 1.09E-50 T 09-03-2017 UA74_RS08450 f6177db4b49f1616b29a465f00a53722 222 SMART SM00563 34 153 7.7E-35 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS08450 f6177db4b49f1616b29a465f00a53722 222 Gene3D G3DSA:3.40.1130.10 6 197 1.1E-32 T 09-03-2017 UA74_RS14125 4a7bf2cd7a81d39e4350beaa6e909be8 265 PIRSF PIRSF017393 1 264 2.2E-92 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS14125 4a7bf2cd7a81d39e4350beaa6e909be8 265 SUPERFAMILY SSF53335 12 248 1.21E-44 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14125 4a7bf2cd7a81d39e4350beaa6e909be8 265 Pfam PF04672 S-adenosyl methyltransferase 8 263 1.3E-87 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS14125 4a7bf2cd7a81d39e4350beaa6e909be8 265 Gene3D G3DSA:3.40.50.150 5 262 6.5E-101 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:3.40.50.980 23 190 5.5E-34 T 09-03-2017 UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 SUPERFAMILY SSF56801 342 601 8.77E-111 T 09-03-2017 UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 SUPERFAMILY SSF56801 18 294 8.77E-111 T 09-03-2017 UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:3.40.50.980 191 289 2.4E-27 T 09-03-2017 UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:3.40.50.980 339 403 2.4E-27 T 09-03-2017 UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:2.30.38.10 404 465 1.4E-18 T 09-03-2017 UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 Pfam PF00501 AMP-binding enzyme 26 471 9.7E-94 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS28295 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:3.30.300.30 469 591 3.9E-7 T 09-03-2017 UA74_RS30445 541eae0042cbecdbe8a930e224fc115b 309 Hamap MF_00215 Pantothenate kinase [coaA]. 1 309 166.808 T 09-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_RS30445 541eae0042cbecdbe8a930e224fc115b 309 PIRSF PIRSF000545 1 309 1.0E-136 T 09-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_RS30445 541eae0042cbecdbe8a930e224fc115b 309 SUPERFAMILY SSF52540 7 307 4.21E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30445 541eae0042cbecdbe8a930e224fc115b 309 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 89 224 1.5E-10 T 09-03-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 UA74_RS30445 541eae0042cbecdbe8a930e224fc115b 309 Gene3D G3DSA:3.40.50.300 9 308 1.1E-100 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30445 541eae0042cbecdbe8a930e224fc115b 309 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 10 308 1.7E-123 T 09-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_RS11690 0f08cbb0d314cb6323ae7ec73e2c5949 326 SUPERFAMILY SSF51735 104 285 5.13E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11690 0f08cbb0d314cb6323ae7ec73e2c5949 326 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS11690 0f08cbb0d314cb6323ae7ec73e2c5949 326 Gene3D G3DSA:3.40.50.720 32 114 6.6E-7 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11690 0f08cbb0d314cb6323ae7ec73e2c5949 326 Gene3D G3DSA:3.40.50.720 115 286 5.9E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11690 0f08cbb0d314cb6323ae7ec73e2c5949 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 285 1.6E-46 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS11690 0f08cbb0d314cb6323ae7ec73e2c5949 326 SUPERFAMILY SSF52283 39 133 4.76E-9 T 09-03-2017 UA74_RS29280 0ae9e16219b8866613fffe168ba6967b 370 SUPERFAMILY SSF53850 52 369 1.19E-79 T 09-03-2017 UA74_RS29280 0ae9e16219b8866613fffe168ba6967b 370 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 55 369 6.9E-83 T 09-03-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 UA74_RS29280 0ae9e16219b8866613fffe168ba6967b 370 Gene3D G3DSA:3.40.190.10 230 368 7.8E-23 T 09-03-2017 UA74_RS29280 0ae9e16219b8866613fffe168ba6967b 370 Gene3D G3DSA:3.40.190.10 52 203 1.8E-41 T 09-03-2017 UA74_RS29280 0ae9e16219b8866613fffe168ba6967b 370 Pfam PF12849 PBP superfamily domain 45 339 5.9E-57 T 09-03-2017 IPR024370 PBP domain UA74_RS29280 0ae9e16219b8866613fffe168ba6967b 370 PIRSF PIRSF002756 6 370 1.5E-109 T 09-03-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 UA74_RS21215 3c7b7cf9ee57854f13fd581c4b76ca9c 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.6E-24 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21215 3c7b7cf9ee57854f13fd581c4b76ca9c 78 Gene3D G3DSA:2.30.170.40 2 76 1.9E-30 T 09-03-2017 UA74_RS21215 3c7b7cf9ee57854f13fd581c4b76ca9c 78 Pfam PF00830 Ribosomal L28 family 4 61 1.9E-22 T 09-03-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21215 3c7b7cf9ee57854f13fd581c4b76ca9c 78 SUPERFAMILY SSF143800 2 75 2.94E-25 T 09-03-2017 UA74_RS21215 3c7b7cf9ee57854f13fd581c4b76ca9c 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 19.259 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 38 226 1.0E-26 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 276 493 1.2E-52 T 09-03-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 SUPERFAMILY SSF52922 533 630 1.88E-10 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 30 626 1.8E-196 T 09-03-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 Gene3D G3DSA:3.40.50.970 241 442 4.7E-73 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 SUPERFAMILY SSF52518 250 516 1.42E-60 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 Gene3D G3DSA:3.40.50.920 532 604 8.2E-6 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 Gene3D G3DSA:3.40.920.10 30 230 7.1E-24 T 09-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 UA74_RS02635 39a56ff08f01f7872305d8b648445d88 637 SUPERFAMILY SSF53323 32 244 4.58E-17 T 09-03-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 Gene3D G3DSA:3.40.47.10 142 193 8.2E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 Gene3D G3DSA:3.40.47.10 277 392 8.2E-49 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 SUPERFAMILY SSF53901 5 270 4.95E-83 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 SUPERFAMILY SSF53901 272 390 4.94E-34 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 Gene3D G3DSA:3.40.47.10 5 123 3.0E-73 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 Gene3D G3DSA:3.40.47.10 194 276 3.0E-73 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 Pfam PF02803 Thiolase, C-terminal domain 271 391 9.3E-39 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 PIRSF PIRSF000429 2 394 9.1E-112 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 3.7E-130 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 09-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 Pfam PF00108 Thiolase, N-terminal domain 5 262 3.5E-98 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 UA74_RS07315 5293b39c29ea8317ddc4336e80e2a180 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 09-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 UA74_RS28110 861b80a5b762aaba44fef7904ab9414d 317 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 312 6.5E-110 T 09-03-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family UA74_RS28110 861b80a5b762aaba44fef7904ab9414d 317 SUPERFAMILY SSF56059 131 313 6.42E-11 T 09-03-2017 UA74_RS22275 8e60c2824fee23bfeab4f660a878fafa 265 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 20 239 6.3E-20 T 09-03-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 UA74_RS22275 8e60c2824fee23bfeab4f660a878fafa 265 SUPERFAMILY SSF100950 15 255 1.79E-54 T 09-03-2017 UA74_RS22275 8e60c2824fee23bfeab4f660a878fafa 265 Gene3D G3DSA:3.40.50.1360 14 255 1.4E-57 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 SUPERFAMILY SSF81665 182 232 4.84E-11 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 SUPERFAMILY SSF81665 329 422 4.84E-11 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 SUPERFAMILY SSF81665 677 696 4.84E-11 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 430 436 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 564 5.4E-25 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 278 292 5.4E-25 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 651 663 5.4E-25 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 647 5.4E-25 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 585 5.4E-25 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 428 442 5.4E-25 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 202 708 6.7E-87 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Pfam PF00403 Heavy-metal-associated domain 1 54 1.0E-10 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 ProSitePatterns PS01229 Hypothetical cof family signature 2. 628 650 - T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 SUPERFAMILY SSF56784 509 728 2.03E-55 T 09-03-2017 IPR023214 HAD-like domain UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 SUPERFAMILY SSF56784 426 446 2.03E-55 T 09-03-2017 IPR023214 HAD-like domain UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 SUPERFAMILY SSF81653 234 328 3.92E-25 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Gene3D G3DSA:3.30.70.100 1 56 3.3E-18 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Pfam PF00122 E1-E2 ATPase 201 419 3.3E-63 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Pfam PF00702 haloacid dehalogenase-like hydrolase 424 642 1.6E-45 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 600 616 2.5E-6 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 628 644 2.5E-6 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 659 684 2.5E-6 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Gene3D G3DSA:3.40.1110.10 444 555 2.2E-21 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 SUPERFAMILY SSF55008 1 56 3.67E-14 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Gene3D G3DSA:3.40.50.1000 556 696 2.0E-50 T 09-03-2017 IPR023214 HAD-like domain UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Gene3D G3DSA:3.40.50.1000 400 443 2.0E-50 T 09-03-2017 IPR023214 HAD-like domain UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 147 730 3.5E-175 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 193 731 4.0E-150 T 09-03-2017 UA74_RS07395 a451b1b61717e7d7d459105f0e141344 756 Gene3D G3DSA:2.70.150.10 193 329 1.4E-27 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS22240 999accef9cfca7ebc45d5885318e436a 373 SUPERFAMILY SSF55347 135 320 1.34E-25 T 09-03-2017 UA74_RS22240 999accef9cfca7ebc45d5885318e436a 373 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 123 1.4E-15 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS22240 999accef9cfca7ebc45d5885318e436a 373 Gene3D G3DSA:3.40.50.720 6 147 4.2E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22240 999accef9cfca7ebc45d5885318e436a 373 Gene3D G3DSA:3.30.360.10 148 349 1.5E-22 T 09-03-2017 UA74_RS22240 999accef9cfca7ebc45d5885318e436a 373 SUPERFAMILY SSF51735 7 153 1.1E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05535 2f545f5c8208c4842d386b3c8f3c6273 437 SUPERFAMILY SSF53383 17 432 1.07E-109 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS05535 2f545f5c8208c4842d386b3c8f3c6273 437 Pfam PF00202 Aminotransferase class-III 26 430 4.7E-85 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS05535 2f545f5c8208c4842d386b3c8f3c6273 437 Gene3D G3DSA:3.40.640.10 60 311 1.7E-69 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS05535 2f545f5c8208c4842d386b3c8f3c6273 437 Gene3D G3DSA:3.90.1150.10 312 432 1.8E-31 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS05535 2f545f5c8208c4842d386b3c8f3c6273 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS00130 9c8f08db3cf790b374fa4b75d8b2e4f5 488 Gene3D G3DSA:3.40.710.10 144 483 2.2E-86 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS00130 9c8f08db3cf790b374fa4b75d8b2e4f5 488 SUPERFAMILY SSF56601 138 483 5.45E-75 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS00130 9c8f08db3cf790b374fa4b75d8b2e4f5 488 SUPERFAMILY SSF56519 74 119 8.37E-6 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UA74_RS00130 9c8f08db3cf790b374fa4b75d8b2e4f5 488 Pfam PF00905 Penicillin binding protein transpeptidase domain 157 481 7.4E-66 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_RS00130 9c8f08db3cf790b374fa4b75d8b2e4f5 488 Gene3D G3DSA:3.90.1310.10 75 143 6.5E-8 T 09-03-2017 UA74_RS24285 2f1c20393e5e9f6905cff9e9372a0fea 284 SUPERFAMILY SSF161098 8 284 2.24E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24285 2f1c20393e5e9f6905cff9e9372a0fea 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 269 2.0E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24285 2f1c20393e5e9f6905cff9e9372a0fea 284 Gene3D G3DSA:1.10.3720.10 4 272 1.0E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21245 487a7c8fda05c9b235a0eddd382b9ede 416 Pfam PF00534 Glycosyl transferases group 1 228 394 1.3E-21 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS21245 487a7c8fda05c9b235a0eddd382b9ede 416 SUPERFAMILY SSF53756 19 143 1.53E-68 T 09-03-2017 UA74_RS21245 487a7c8fda05c9b235a0eddd382b9ede 416 SUPERFAMILY SSF53756 175 412 1.53E-68 T 09-03-2017 UA74_RS21245 487a7c8fda05c9b235a0eddd382b9ede 416 Gene3D G3DSA:3.40.50.2000 206 393 1.1E-24 T 09-03-2017 UA74_RS21245 487a7c8fda05c9b235a0eddd382b9ede 416 Pfam PF13439 Glycosyltransferase Family 4 32 219 2.7E-19 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS10405 fcaaa7ab8fcf68f9de6d30ec50a7b0f2 111 SUPERFAMILY SSF51182 13 109 2.06E-23 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS10405 fcaaa7ab8fcf68f9de6d30ec50a7b0f2 111 PIRSF PIRSF029883 4 110 3.1E-25 T 09-03-2017 IPR025499 Pectin degradation protein KdgF UA74_RS10405 fcaaa7ab8fcf68f9de6d30ec50a7b0f2 111 Gene3D G3DSA:2.60.120.10 13 106 2.0E-27 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS10405 fcaaa7ab8fcf68f9de6d30ec50a7b0f2 111 Pfam PF07883 Cupin domain 33 88 9.9E-14 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 Gene3D G3DSA:3.40.50.720 2 178 3.4E-64 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 36.742 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 Gene3D G3DSA:1.10.1040.10 180 327 3.6E-54 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 159 3.5E-53 T 09-03-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 SUPERFAMILY SSF51735 3 178 2.88E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 319 4.2E-50 T 09-03-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 1.0E-46 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 1.0E-46 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 1.0E-46 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 1.0E-46 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 1.0E-46 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 1.0E-46 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 PIRSF PIRSF000114 1 332 1.7E-100 T 09-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 UA74_RS26005 43afe67fb7a81e5bd3f0e4460ce8e305 334 SUPERFAMILY SSF48179 180 332 2.15E-51 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 PIRSF PIRSF001500 1 296 1.4E-52 T 09-03-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 Gene3D G3DSA:3.40.190.10 3 112 1.1E-19 T 09-03-2017 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 242 249 - T 09-03-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 Pfam PF00800 Prephenate dehydratase 4 201 3.3E-37 T 09-03-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 Pfam PF01842 ACT domain 215 280 4.2E-10 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 SUPERFAMILY SSF53850 3 208 8.32E-39 T 09-03-2017 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 Gene3D G3DSA:3.30.70.260 209 294 4.9E-29 T 09-03-2017 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 SUPERFAMILY SSF55021 202 294 1.07E-23 T 09-03-2017 UA74_RS00575 bc4201541cea910ce3efbed2c529e0ae 333 Gene3D G3DSA:3.40.190.10 113 189 1.0E-18 T 09-03-2017 UA74_RS20705 0ae2aa086b971751030af8cd6a9d8e8e 353 SUPERFAMILY SSF51735 173 283 1.38E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20705 0ae2aa086b971751030af8cd6a9d8e8e 353 Gene3D G3DSA:3.90.180.10 1 188 4.2E-31 T 09-03-2017 IPR011032 GroES-like UA74_RS20705 0ae2aa086b971751030af8cd6a9d8e8e 353 Pfam PF16912 Glucose dehydrogenase C-terminus 145 348 1.2E-64 T 09-03-2017 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 UA74_RS20705 0ae2aa086b971751030af8cd6a9d8e8e 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 1.3E-13 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS20705 0ae2aa086b971751030af8cd6a9d8e8e 353 Gene3D G3DSA:3.40.50.720 189 278 4.8E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20705 0ae2aa086b971751030af8cd6a9d8e8e 353 SUPERFAMILY SSF50129 1 183 3.04E-32 T 09-03-2017 IPR011032 GroES-like UA74_RS25040 ce644fb389ba414c097b1a25b17585d0 383 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 112 285 6.0E-61 T 09-03-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 UA74_RS25040 ce644fb389ba414c097b1a25b17585d0 383 Gene3D G3DSA:1.20.810.10 11 381 7.2E-79 T 09-03-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 UA74_RS25040 ce644fb389ba414c097b1a25b17585d0 383 SUPERFAMILY SSF81342 11 288 2.67E-62 T 09-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 TIGRFAM TIGR00510 lipA: lipoyl synthase 17 303 2.1E-96 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 Gene3D G3DSA:3.20.20.70 39 303 4.0E-66 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 SUPERFAMILY SSF102114 35 296 3.92E-61 T 09-03-2017 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 Pfam PF04055 Radical SAM superfamily 81 235 3.8E-12 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 136.441 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 SMART SM00729 71 276 9.4E-14 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 1.4E-7 T 09-03-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_RS25240 8ac918c7f4174f8c66c418e73c9fb36d 333 PIRSF PIRSF005963 5 316 4.8E-119 T 09-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_RS19535 9e1e00015690564b99f378d4373ddd83 384 Pfam PF07728 AAA domain (dynein-related subfamily) 95 237 4.2E-35 T 09-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_RS19535 9e1e00015690564b99f378d4373ddd83 384 SMART SM00382 91 247 1.9E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS19535 9e1e00015690564b99f378d4373ddd83 384 Gene3D G3DSA:3.40.50.300 76 242 1.0E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19535 9e1e00015690564b99f378d4373ddd83 384 SUPERFAMILY SSF52540 72 288 8.77E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 Pfam PF00106 short chain dehydrogenase 7 211 1.0E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 9.4E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 9.4E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 9.4E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.4E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 9.4E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 Gene3D G3DSA:3.40.50.720 2 248 1.1E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.4E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.4E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.4E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30045 f54a10b888477ab2bbc9e45bea138b52 292 SUPERFAMILY SSF51735 6 234 2.04E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09935 7a4d76b80f06c07b51bf9b5bf038d3d7 529 SUPERFAMILY SSF53850 31 525 3.8E-95 T 09-03-2017 UA74_RS09935 7a4d76b80f06c07b51bf9b5bf038d3d7 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 428 5.2E-65 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS09935 7a4d76b80f06c07b51bf9b5bf038d3d7 529 PIRSF PIRSF002741 1 521 7.5E-78 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS09935 7a4d76b80f06c07b51bf9b5bf038d3d7 529 Gene3D G3DSA:3.10.105.10 296 489 7.6E-35 T 09-03-2017 UA74_RS09935 7a4d76b80f06c07b51bf9b5bf038d3d7 529 Gene3D G3DSA:3.40.190.10 186 295 6.6E-21 T 09-03-2017 UA74_RS09935 7a4d76b80f06c07b51bf9b5bf038d3d7 529 Gene3D G3DSA:3.90.76.10 39 185 1.6E-33 T 09-03-2017 UA74_RS20515 355791600ab3957b30e4f4d9d4a25dba 335 Gene3D G3DSA:3.40.50.1100 110 332 1.5E-71 T 09-03-2017 UA74_RS20515 355791600ab3957b30e4f4d9d4a25dba 335 SUPERFAMILY SSF53686 4 332 2.61E-95 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS20515 355791600ab3957b30e4f4d9d4a25dba 335 PIRSF PIRSF006278 1 335 1.5E-116 T 09-03-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase UA74_RS20515 355791600ab3957b30e4f4d9d4a25dba 335 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 334 2.0E-158 T 09-03-2017 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 UA74_RS20515 355791600ab3957b30e4f4d9d4a25dba 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 320 1.2E-43 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS22330 c8a173a110d9396f3356733cec68ab09 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 2.4E-15 T 09-03-2017 IPR004302 Chitin-binding protein, N-terminal UA74_RS22330 c8a173a110d9396f3356733cec68ab09 171 SUPERFAMILY SSF81296 31 170 4.9E-33 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS22330 c8a173a110d9396f3356733cec68ab09 171 Gene3D G3DSA:2.70.50.50 119 170 4.8E-11 T 09-03-2017 UA74_RS22330 c8a173a110d9396f3356733cec68ab09 171 Gene3D G3DSA:2.70.50.50 31 114 9.8E-19 T 09-03-2017 UA74_RS23155 c830aec279708ea468cdddda06adbc3b 226 Gene3D G3DSA:3.30.70.1210 95 219 2.2E-25 T 09-03-2017 UA74_RS23155 c830aec279708ea468cdddda06adbc3b 226 SMART SM01101 1 221 4.6E-57 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS23155 c830aec279708ea468cdddda06adbc3b 226 Pfam PF08798 CRISPR associated protein 2 221 3.6E-52 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS23155 c830aec279708ea468cdddda06adbc3b 226 SUPERFAMILY SSF117987 95 221 4.45E-24 T 09-03-2017 UA74_RS23155 c830aec279708ea468cdddda06adbc3b 226 SUPERFAMILY SSF117987 1 80 8.63E-19 T 09-03-2017 UA74_RS23155 c830aec279708ea468cdddda06adbc3b 226 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 2 221 2.5E-20 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS23155 c830aec279708ea468cdddda06adbc3b 226 Gene3D G3DSA:3.30.70.1200 1 86 1.6E-24 T 09-03-2017 UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 SUPERFAMILY SSF52467 216 388 6.1E-62 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 Gene3D G3DSA:3.40.50.970 32 208 9.7E-73 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 SUPERFAMILY SSF52518 398 599 1.2E-67 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 458 477 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 SUPERFAMILY SSF52518 28 212 1.04E-62 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 Gene3D G3DSA:3.40.50.1220 216 382 4.4E-68 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 Gene3D G3DSA:3.40.50.970 383 588 1.1E-74 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 33 198 2.1E-56 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 33 595 2.6E-231 T 09-03-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 222 357 2.2E-49 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UA74_RS26135 095aed97d3b1de0eaf3327cdfcbab475 608 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 572 2.6E-49 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_RS07905 cc7784811b843844e3e8a9192f61a410 222 SUPERFAMILY SSF52172 1 178 1.04E-34 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS07905 cc7784811b843844e3e8a9192f61a410 222 Gene3D G3DSA:3.40.50.2300 1 120 1.4E-31 T 09-03-2017 UA74_RS07905 cc7784811b843844e3e8a9192f61a410 222 SMART SM00862 145 217 4.0E-22 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS07905 cc7784811b843844e3e8a9192f61a410 222 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS07905 cc7784811b843844e3e8a9192f61a410 222 Gene3D G3DSA:1.10.10.10 124 218 1.5E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07905 cc7784811b843844e3e8a9192f61a410 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 4.4E-20 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS07905 cc7784811b843844e3e8a9192f61a410 222 SMART SM00448 1 112 7.0E-34 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF52777 199 457 9.45E-31 T 09-03-2017 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF52777 20 194 8.12E-31 T 09-03-2017 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.40.50.980 675 804 1.2E-27 T 09-03-2017 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:2.30.38.10 805 882 3.4E-20 T 09-03-2017 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1028 1043 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF47336 997 1070 1.01E-17 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.40.50.980 479 656 5.6E-35 T 09-03-2017 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 SMART SM00823 Phosphopantetheine attachment site 1004 1073 8.7E-4 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 506 914 4.8E-96 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF56801 474 1017 1.57E-118 T 09-03-2017 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:1.10.1200.10 1009 1073 6.1E-24 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Pfam PF00668 Condensation domain 19 324 1.2E-34 T 09-03-2017 IPR001242 Condensation domain UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 ProSitePatterns PS00455 Putative AMP-binding domain signature. 633 644 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.30.300.30 887 1008 1.4E-29 T 09-03-2017 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Pfam PF00501 AMP-binding enzyme 486 892 4.2E-75 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Pfam PF13193 AMP-binding enzyme C-terminal domain 901 974 5.9E-8 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS17005 d418d360adf525cc670860d4ad1800db 1080 Pfam PF00550 Phosphopantetheine attachment site 1006 1069 5.1E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS12325 52badad94dcc2a4fc2a9c77cfce6c31f 418 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 200 387 1.2E-66 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UA74_RS12325 52badad94dcc2a4fc2a9c77cfce6c31f 418 SUPERFAMILY SSF52507 17 186 3.01E-56 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_RS12325 52badad94dcc2a4fc2a9c77cfce6c31f 418 Gene3D G3DSA:3.40.50.10300 197 417 8.4E-78 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UA74_RS12325 52badad94dcc2a4fc2a9c77cfce6c31f 418 SUPERFAMILY SSF102645 198 416 4.84E-66 T 09-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UA74_RS12325 52badad94dcc2a4fc2a9c77cfce6c31f 418 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 19 412 2.1E-117 T 09-03-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 UA74_RS12325 52badad94dcc2a4fc2a9c77cfce6c31f 418 Pfam PF02441 Flavoprotein 20 144 6.3E-30 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_RS12325 52badad94dcc2a4fc2a9c77cfce6c31f 418 Gene3D G3DSA:3.40.50.1950 14 194 9.4E-61 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_RS04145 9c2a2e4265fc4e538e6c1acfc53d4b28 360 Gene3D G3DSA:3.30.540.10 197 344 1.2E-44 T 09-03-2017 UA74_RS04145 9c2a2e4265fc4e538e6c1acfc53d4b28 360 Gene3D G3DSA:3.30.540.10 24 196 2.2E-64 T 09-03-2017 UA74_RS04145 9c2a2e4265fc4e538e6c1acfc53d4b28 360 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 26 333 1.2E-143 T 09-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UA74_RS04145 9c2a2e4265fc4e538e6c1acfc53d4b28 360 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 26 337 6.2E-114 T 09-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UA74_RS04145 9c2a2e4265fc4e538e6c1acfc53d4b28 360 SUPERFAMILY SSF56655 24 336 8.16E-115 T 09-03-2017 UA74_RS04145 9c2a2e4265fc4e538e6c1acfc53d4b28 360 PIRSF PIRSF004532 24 344 8.5E-149 T 09-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UA74_RS12555 5cde882c80d49943be9cd00415766549 121 SUPERFAMILY SSF54534 6 119 1.34E-25 T 09-03-2017 UA74_RS12555 5cde882c80d49943be9cd00415766549 121 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 26 115 4.1E-18 T 09-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 UA74_RS12555 5cde882c80d49943be9cd00415766549 121 Gene3D G3DSA:3.10.50.40 9 118 6.8E-25 T 09-03-2017 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 SUPERFAMILY SSF57716 221 267 9.41E-12 T 09-03-2017 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 SUPERFAMILY SSF81624 2 123 2.09E-22 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 SMART SM01232 122 214 3.2E-30 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 SUPERFAMILY SSF46946 121 205 1.91E-22 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 SMART SM00898 2 108 6.1E-17 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 Gene3D G3DSA:3.20.190.10 2 122 1.6E-12 T 09-03-2017 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 Gene3D G3DSA:1.10.8.50 123 267 7.5E-41 T 09-03-2017 UA74_RS08085 d8e5f2f964feb68a01489569947afa9f 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 206 1.1E-16 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_RS22350 862863df87aa2908f94679e69b66995e 237 Gene3D G3DSA:1.20.120.530 98 226 1.0E-19 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS22350 862863df87aa2908f94679e69b66995e 237 SMART SM00895 100 221 9.4E-19 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS22350 862863df87aa2908f94679e69b66995e 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 3.7E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS22350 862863df87aa2908f94679e69b66995e 237 SMART SM00345 13 71 8.4E-12 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS22350 862863df87aa2908f94679e69b66995e 237 SUPERFAMILY SSF48008 98 225 4.97E-19 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS22350 862863df87aa2908f94679e69b66995e 237 Gene3D G3DSA:1.10.10.10 5 72 4.5E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22350 862863df87aa2908f94679e69b66995e 237 Pfam PF07729 FCD domain 100 220 2.3E-18 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS22350 862863df87aa2908f94679e69b66995e 237 SUPERFAMILY SSF46785 4 75 2.95E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 Pfam PF04055 Radical SAM superfamily 167 336 5.8E-21 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 Gene3D G3DSA:3.80.30.20 160 389 1.4E-61 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 164 184 - T 09-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 2 452 1.5E-118 T 09-03-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 SUPERFAMILY SSF102114 132 382 3.27E-45 T 09-03-2017 UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 448 5.7E-100 T 09-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 1 455 57.43 T 09-03-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 SMART SM00729 160 378 8.0E-39 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 Gene3D G3DSA:2.40.50.140 393 457 8.8E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS09600 2f9f56c25450cbc613cba7b5e035a5c1 465 Pfam PF00919 Uncharacterized protein family UPF0004 2 94 1.2E-26 T 09-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 UA74_RS09580 e88dbe89b3b2b1622c87226dba4306c2 844 SUPERFAMILY SSF46785 763 828 2.18E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09580 e88dbe89b3b2b1622c87226dba4306c2 844 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 101 227 7.8E-9 T 09-03-2017 IPR025199 DNA translocase FtsK, 4TM region UA74_RS09580 e88dbe89b3b2b1622c87226dba4306c2 844 SUPERFAMILY SSF52540 435 733 9.92E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09580 e88dbe89b3b2b1622c87226dba4306c2 844 Pfam PF09397 Ftsk gamma domain 767 823 8.4E-21 T 09-03-2017 IPR018541 FtsK gamma domain UA74_RS09580 e88dbe89b3b2b1622c87226dba4306c2 844 Pfam PF01580 FtsK/SpoIIIE family 461 661 2.4E-59 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_RS09580 e88dbe89b3b2b1622c87226dba4306c2 844 SMART SM00843 762 826 1.2E-27 T 09-03-2017 IPR018541 FtsK gamma domain UA74_RS09580 e88dbe89b3b2b1622c87226dba4306c2 844 Gene3D G3DSA:3.40.50.300 435 727 2.3E-81 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 19 437 1.0E-134 T 09-03-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 SUPERFAMILY SSF56436 180 440 1.28E-77 T 09-03-2017 IPR016187 C-type lectin fold UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 Pfam PF12867 DinB superfamily 21 152 1.3E-26 T 09-03-2017 IPR024775 DinB-like domain UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 SUPERFAMILY SSF109854 15 148 6.96E-21 T 09-03-2017 UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 Gene3D G3DSA:3.90.1580.10 177 442 8.0E-80 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 Gene3D G3DSA:1.20.120.450 15 126 2.0E-5 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 Pfam PF03781 Sulfatase-modifying factor enzyme 1 179 438 1.4E-65 T 09-03-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 UA74_RS11520 f77dd6930c95290934ff9280b43a671d 446 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 440 52.561 T 09-03-2017 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 Gene3D G3DSA:3.30.1490.70 158 200 4.9E-13 T 09-03-2017 UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 Gene3D G3DSA:3.30.1490.70 4 32 4.9E-13 T 09-03-2017 UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 SUPERFAMILY SSF50249 202 339 1.63E-12 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 SUPERFAMILY SSF56091 7 199 6.48E-43 T 09-03-2017 UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 Gene3D G3DSA:3.30.470.30 33 145 7.2E-25 T 09-03-2017 UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 Pfam PF01068 ATP dependent DNA ligase domain 11 199 1.4E-31 T 09-03-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 Gene3D G3DSA:2.40.50.140 202 339 5.0E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS23765 c0538684679ef1487481ec39de5f88eb 365 Pfam PF04679 ATP dependent DNA ligase C terminal region 221 333 5.2E-16 T 09-03-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 UA74_RS26865 f717905b64fa984df75b23103df9f0de 377 Pfam PF00534 Glycosyl transferases group 1 195 349 1.3E-27 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS26865 f717905b64fa984df75b23103df9f0de 377 Pfam PF13439 Glycosyltransferase Family 4 16 172 1.0E-9 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS26865 f717905b64fa984df75b23103df9f0de 377 SUPERFAMILY SSF53756 8 362 7.14E-65 T 09-03-2017 UA74_RS26865 f717905b64fa984df75b23103df9f0de 377 Gene3D G3DSA:3.40.50.2000 177 349 7.2E-29 T 09-03-2017 UA74_RS11910 dcd740576e3a9003ebb7931a18c2bea8 421 Gene3D G3DSA:3.40.190.10 145 315 2.2E-19 T 09-03-2017 UA74_RS11910 dcd740576e3a9003ebb7931a18c2bea8 421 Pfam PF13416 Bacterial extracellular solute-binding protein 49 348 3.4E-31 T 09-03-2017 UA74_RS11910 dcd740576e3a9003ebb7931a18c2bea8 421 Gene3D G3DSA:3.40.190.10 316 347 2.7E-30 T 09-03-2017 UA74_RS11910 dcd740576e3a9003ebb7931a18c2bea8 421 Gene3D G3DSA:3.40.190.10 22 144 2.7E-30 T 09-03-2017 UA74_RS11910 dcd740576e3a9003ebb7931a18c2bea8 421 SUPERFAMILY SSF53850 28 419 2.82E-56 T 09-03-2017 UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 SUPERFAMILY SSF51604 111 357 4.85E-66 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 SMART SM00922 142 239 1.9E-28 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 Gene3D G3DSA:3.20.20.120 119 356 2.4E-67 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 189 220 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 Gene3D G3DSA:3.30.390.10 1 118 7.3E-26 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 23 123 4.2E-12 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 Pfam PF13378 Enolase C-terminal domain-like 144 352 3.3E-58 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS23855 6de1863652af38595ecfe52e0ebb77bd 362 SUPERFAMILY SSF54826 1 125 1.2E-24 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS28245 510c10a422b75044507cdf67df84740a 467 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 84 5.0E-21 T 09-03-2017 IPR024962 YukD-like UA74_RS28245 510c10a422b75044507cdf67df84740a 467 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 459 4.8E-85 T 09-03-2017 IPR006707 Type VII secretion system membrane protein EccD UA74_RS28245 510c10a422b75044507cdf67df84740a 467 PIRSF PIRSF017804 1 462 3.6E-121 T 09-03-2017 IPR006707 Type VII secretion system membrane protein EccD UA74_RS26925 1bb059ce463c16dba95ea6811fb60fe4 291 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS26925 1bb059ce463c16dba95ea6811fb60fe4 291 SMART SM00382 26 204 2.4E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26925 1bb059ce463c16dba95ea6811fb60fe4 291 Gene3D G3DSA:3.40.50.300 2 219 1.6E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26925 1bb059ce463c16dba95ea6811fb60fe4 291 SUPERFAMILY SSF52540 2 222 1.88E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26925 1bb059ce463c16dba95ea6811fb60fe4 291 Pfam PF00005 ABC transporter 18 156 2.1E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 262 372 2.3E-32 T 09-03-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 SUPERFAMILY SSF55979 146 261 2.77E-19 T 09-03-2017 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 387 2.4E-95 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 39 4.9E-7 T 09-03-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 54 134 9.8E-22 T 09-03-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 SMART SM00480 17 383 7.5E-121 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 SUPERFAMILY SSF55979 1 134 1.75E-19 T 09-03-2017 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 SUPERFAMILY SSF55979 262 387 1.3E-30 T 09-03-2017 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 Gene3D G3DSA:3.10.150.10 266 388 2.2E-41 T 09-03-2017 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF02767 DNA polymerase III beta subunit, central domain 146 260 1.1E-31 T 09-03-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 PIRSF PIRSF000804 1 388 6.2E-97 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 Gene3D G3DSA:3.10.150.10 1 135 6.5E-28 T 09-03-2017 UA74_RS00010 1e26a031a5d98a6d7446cfe7945b6486 389 Gene3D G3DSA:3.10.150.10 142 264 1.8E-30 T 09-03-2017 UA74_RS29120 dabf5283d1e01d0689dba97fb30a78cc 185 Pfam PF13563 2'-5' RNA ligase superfamily 37 165 3.4E-21 T 09-03-2017 UA74_RS29120 dabf5283d1e01d0689dba97fb30a78cc 185 SUPERFAMILY SSF55144 17 182 2.46E-15 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase UA74_RS29120 dabf5283d1e01d0689dba97fb30a78cc 185 Gene3D G3DSA:3.90.1140.10 31 182 5.5E-12 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 6.2E-26 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 315 336 6.2E-26 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 6.2E-26 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 6.2E-26 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 SUPERFAMILY SSF55190 17 102 1.7E-13 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 SUPERFAMILY SSF52374 116 464 2.67E-85 T 09-03-2017 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 Hamap MF_00123 Arginine--tRNA ligase [argS]. 13 590 25.595 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 Gene3D G3DSA:3.30.1360.70 7 108 6.8E-23 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 Gene3D G3DSA:3.40.50.620 118 470 3.8E-107 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 128 139 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 SUPERFAMILY SSF47323 466 590 1.05E-32 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 SMART SM01016 13 92 9.4E-22 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 590 5.1E-146 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 Gene3D G3DSA:1.10.730.10 471 590 4.5E-36 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 Pfam PF00750 tRNA synthetases class I (R) 119 457 1.6E-114 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 13 92 2.0E-15 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 Pfam PF05746 DALR anticodon binding domain 472 590 3.0E-32 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_RS16130 f917309e1660af0a9f77132287dd0750 590 SMART SM00836 472 590 3.6E-38 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_RS30290 cf0c12c7f028cc0ae81b2af72961cc12 190 Pfam PF08044 Domain of unknown function (DUF1707) 15 67 1.4E-17 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS10530 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 1.1E-20 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_RS10530 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 218 1.1E-20 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_RS10530 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 1.1E-20 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_RS10530 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 153 174 1.1E-20 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_RS10530 596f3968270cb04153252d770de190ec 338 Gene3D G3DSA:3.40.50.620 6 217 2.4E-73 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS10530 596f3968270cb04153252d770de190ec 338 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS10530 596f3968270cb04153252d770de190ec 338 Pfam PF00579 tRNA synthetases class I (W and Y) 10 292 1.4E-56 T 09-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS10530 596f3968270cb04153252d770de190ec 338 Gene3D G3DSA:1.10.240.10 218 304 1.5E-27 T 09-03-2017 UA74_RS10530 596f3968270cb04153252d770de190ec 338 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 6 338 1.3E-86 T 09-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_RS10530 596f3968270cb04153252d770de190ec 338 SUPERFAMILY SSF52374 10 338 5.63E-78 T 09-03-2017 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF04898 Glutamate synthase central domain 494 780 4.0E-108 T 09-03-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF01645 Conserved region in glutamate synthase 846 1210 5.2E-150 T 09-03-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 SUPERFAMILY SSF56235 22 469 5.52E-136 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:3.60.20.10 22 478 7.8E-170 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF00310 Glutamine amidotransferases class-II 22 467 7.9E-161 T 09-03-2017 IPR017932 Glutamine amidotransferase type 2 domain UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:3.20.20.70 479 833 1.3E-97 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 SUPERFAMILY SSF69336 1265 1526 4.19E-88 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 SUPERFAMILY SSF51395 482 1243 1.06E-253 T 09-03-2017 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:2.160.20.60 1270 1540 1.2E-100 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:3.20.20.70 878 1248 1.5E-174 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS21405 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF01493 GXGXG motif 1296 1473 1.4E-74 T 09-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS20095 2d795d173f97328b744ee076d06612e1 287 Gene3D G3DSA:3.40.50.720 8 178 3.4E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20095 2d795d173f97328b744ee076d06612e1 287 Gene3D G3DSA:1.10.3640.10 181 282 1.8E-41 T 09-03-2017 UA74_RS20095 2d795d173f97328b744ee076d06612e1 287 Pfam PF16896 Phosphogluconate dehydrogenase (decarboxylating) C-term 128 281 2.3E-62 T 09-03-2017 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal UA74_RS20095 2d795d173f97328b744ee076d06612e1 287 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 10 95 6.1E-7 T 09-03-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_RS20095 2d795d173f97328b744ee076d06612e1 287 SUPERFAMILY SSF51735 10 174 5.88E-14 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 Gene3D G3DSA:3.40.50.1100 43 147 1.3E-38 T 09-03-2017 UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 09-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 Gene3D G3DSA:3.40.50.1100 2 42 3.4E-67 T 09-03-2017 UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 Gene3D G3DSA:3.40.50.1100 153 313 3.4E-67 T 09-03-2017 UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 SMART SM00116 409 454 3.6E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 SMART SM00116 339 392 0.05 T 09-03-2017 IPR000644 CBS domain UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 SUPERFAMILY SSF54631 325 455 3.28E-17 T 09-03-2017 UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 SUPERFAMILY SSF53686 1 317 9.95E-95 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 454 3.2E-197 T 09-03-2017 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 Gene3D G3DSA:3.10.580.10 333 454 7.8E-22 T 09-03-2017 UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 Pfam PF00571 CBS domain 402 454 1.4E-6 T 09-03-2017 IPR000644 CBS domain UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 Pfam PF00571 CBS domain 326 391 1.5E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS03860 8883c1a076b6f2a60f578b3b1a8f55be 457 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 296 1.0E-65 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 Pfam PF01037 Lrp/AsnC ligand binding domain 82 123 1.1E-7 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 SUPERFAMILY SSF46785 1 60 8.69E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 3.5E-17 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 SUPERFAMILY SSF54909 63 136 2.41E-10 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 Gene3D G3DSA:3.30.70.920 55 125 2.2E-10 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.8E-12 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.8E-12 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.8E-12 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 Gene3D G3DSA:1.10.10.10 2 52 8.8E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29070 a85af60ef022f6dff6ed6f94a8714824 162 SMART SM00344 1 108 2.2E-22 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_RS05190 6b3aeeb7c66c23b370cfb5a70593bb96 74 Gene3D G3DSA:1.10.1200.10 1 66 3.0E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05190 6b3aeeb7c66c23b370cfb5a70593bb96 74 SUPERFAMILY SSF47336 1 69 1.7E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05190 6b3aeeb7c66c23b370cfb5a70593bb96 74 Pfam PF00550 Phosphopantetheine attachment site 1 61 1.5E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 SMART SM00420 6 58 7.3E-12 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 Pfam PF00455 DeoR C terminal sensor domain 75 233 5.9E-50 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 Gene3D G3DSA:1.10.10.10 5 53 3.0E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 SUPERFAMILY SSF100950 74 235 1.99E-29 T 09-03-2017 UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 Gene3D G3DSA:3.40.50.1360 75 215 3.1E-10 T 09-03-2017 UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 SMART SM01134 73 234 6.8E-70 T 09-03-2017 UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 5.9E-13 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 SUPERFAMILY SSF46785 5 60 2.77E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.3E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS16720 4f167c6feb0969c5c13069a2df32cf06 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.3E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 267 275 - T 09-03-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 SUPERFAMILY SSF53795 243 605 6.18E-154 T 09-03-2017 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 606 50.005 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 PIRSF PIRSF001348 2 606 1.1E-282 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 Gene3D G3DSA:3.90.228.20 243 312 6.8E-33 T 09-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 Gene3D G3DSA:3.90.228.20 335 605 1.6E-98 T 09-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 Gene3D G3DSA:3.40.449.10 11 242 3.7E-92 T 09-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 SUPERFAMILY SSF68923 12 242 7.32E-97 T 09-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UA74_RS30020 25ec9c7365d31374915afba3fc166ec6 606 Pfam PF00821 Phosphoenolpyruvate carboxykinase 21 605 1.5E-280 T 09-03-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_RS10880 bc4ce5e9bece0e52c55c1d96a2587314 188 SUPERFAMILY SSF51182 65 185 4.69E-20 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS10880 bc4ce5e9bece0e52c55c1d96a2587314 188 SMART SM00530 17 72 1.6E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS10880 bc4ce5e9bece0e52c55c1d96a2587314 188 Gene3D G3DSA:1.10.260.40 14 111 4.6E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS10880 bc4ce5e9bece0e52c55c1d96a2587314 188 Pfam PF01381 Helix-turn-helix 18 70 5.2E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS10880 bc4ce5e9bece0e52c55c1d96a2587314 188 Gene3D G3DSA:2.60.120.10 112 185 7.3E-21 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS10880 bc4ce5e9bece0e52c55c1d96a2587314 188 SUPERFAMILY SSF47413 13 78 2.0E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS04560 d629f91113218c6acb7fc9a158525c73 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 122 7.3E-7 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS04560 d629f91113218c6acb7fc9a158525c73 129 SUPERFAMILY SSF54593 8 128 3.49E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS04560 d629f91113218c6acb7fc9a158525c73 129 Gene3D G3DSA:3.10.180.10 7 128 1.2E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15730 6f2683c83fb31f87ccdc27f2cd028752 583 SMART SM00857 31 185 8.2E-6 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UA74_RS15730 6f2683c83fb31f87ccdc27f2cd028752 583 SUPERFAMILY SSF53041 31 178 2.75E-10 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UA74_RS15730 6f2683c83fb31f87ccdc27f2cd028752 583 Pfam PF07508 Recombinase 222 347 2.6E-18 T 09-03-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 UA74_RS15730 6f2683c83fb31f87ccdc27f2cd028752 583 Pfam PF00239 Resolvase, N terminal domain 32 178 5.4E-9 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UA74_RS15730 6f2683c83fb31f87ccdc27f2cd028752 583 Pfam PF13408 Recombinase zinc beta ribbon domain 372 429 3.5E-6 T 09-03-2017 IPR025827 Recombinase zinc beta ribbon domain UA74_RS15730 6f2683c83fb31f87ccdc27f2cd028752 583 Gene3D G3DSA:3.40.50.1390 31 165 7.1E-5 T 09-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 Gene3D G3DSA:3.40.50.720 3 230 8.2E-83 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 SUPERFAMILY SSF51735 3 230 1.34E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 1.9E-6 T 09-03-2017 UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.3E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.3E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.3E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.3E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.3E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.3E-44 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 7.3E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 7.3E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 7.3E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11610 45a11c60ec52ebaa90fe17fda8099369 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 1.0E-60 T 09-03-2017 UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 Pfam PF00381 PTS HPr component phosphorylation site 3 83 1.6E-24 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 PRINTS PR00107 Phosphocarrier protein signature 54 71 3.0E-12 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 PRINTS PR00107 Phosphocarrier protein signature 39 54 3.0E-12 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.0E-12 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 Gene3D G3DSA:3.30.1340.10 1 84 1.1E-25 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 SUPERFAMILY SSF55594 1 87 1.7E-21 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 09-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site UA74_RS12180 0c5dbb5e379cdcad69b42e0e0f028b39 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 3.1E-23 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 SMART SM00347 48 149 1.4E-23 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 Gene3D G3DSA:1.10.10.10 29 162 3.0E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 1.4E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 1.4E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 1.4E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 Pfam PF01047 MarR family 62 114 4.8E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_RS07335 69aaecf7d2d1f397ef6f429637b8f8a3 172 SUPERFAMILY SSF46785 30 164 1.1E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 SUPERFAMILY SSF54211 2 170 4.17E-29 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 404 499 4.5E-22 T 09-03-2017 IPR025158 Mg chelatase-related protein, C-terminal domain UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 SMART SM00382 211 393 4.2E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 499 1.5E-129 T 09-03-2017 IPR004482 Mg chelatase-related protein UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 Gene3D G3DSA:3.30.230.10 7 169 7.5E-30 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 2.0E-33 T 09-03-2017 UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 SUPERFAMILY SSF52540 188 498 2.3E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 Pfam PF01078 Magnesium chelatase, subunit ChlI 191 393 5.8E-79 T 09-03-2017 IPR000523 Magnesium chelatase ChlI domain UA74_RS09010 65e488b0c43be929fee0c6004b9a7258 504 Gene3D G3DSA:3.40.50.300 191 387 6.3E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20110 cc28ea916c9ed229e1b07dca7ad2e2fa 392 Gene3D G3DSA:2.130.10.10 54 388 4.4E-90 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS20110 cc28ea916c9ed229e1b07dca7ad2e2fa 392 SUPERFAMILY SSF51004 78 390 8.24E-47 T 09-03-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain UA74_RS20110 cc28ea916c9ed229e1b07dca7ad2e2fa 392 Pfam PF10282 Lactonase, 7-bladed beta-propeller 62 389 8.0E-96 T 09-03-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 UA74_RS10285 2c434718387e6e58986b955e78b1b7ca 313 Gene3D G3DSA:3.40.190.10 96 198 3.0E-18 T 09-03-2017 UA74_RS10285 2c434718387e6e58986b955e78b1b7ca 313 Gene3D G3DSA:3.40.190.10 199 249 3.8E-7 T 09-03-2017 UA74_RS10285 2c434718387e6e58986b955e78b1b7ca 313 Gene3D G3DSA:1.10.10.10 4 86 1.3E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10285 2c434718387e6e58986b955e78b1b7ca 313 Pfam PF03466 LysR substrate binding domain 96 293 1.1E-28 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS10285 2c434718387e6e58986b955e78b1b7ca 313 SUPERFAMILY SSF46785 2 96 3.63E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10285 2c434718387e6e58986b955e78b1b7ca 313 SUPERFAMILY SSF53850 94 294 8.24E-30 T 09-03-2017 UA74_RS10285 2c434718387e6e58986b955e78b1b7ca 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.2E-18 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS06810 c01217515e776e6813b89b72bd9b182d 158 SUPERFAMILY SSF55729 4 128 3.21E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS06810 c01217515e776e6813b89b72bd9b182d 158 Pfam PF00583 Acetyltransferase (GNAT) family 52 122 9.8E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS06810 c01217515e776e6813b89b72bd9b182d 158 Gene3D G3DSA:3.40.630.30 32 130 2.3E-19 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 210 3.1E-20 T 09-03-2017 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 SUPERFAMILY SSF51905 178 354 1.34E-7 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 SUPERFAMILY SSF51905 10 207 5.83E-34 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.4E-8 T 09-03-2017 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 2.4E-8 T 09-03-2017 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 302 2.4E-8 T 09-03-2017 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 Gene3D G3DSA:3.50.50.60 148 214 9.4E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 Gene3D G3DSA:3.50.50.60 260 292 9.4E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 Gene3D G3DSA:3.50.50.60 294 356 1.6E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 Gene3D G3DSA:3.50.50.60 9 147 1.6E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 174 198 4.0E-9 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS06610 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 4.0E-9 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 Pfam PF08281 Sigma-70, region 4 114 164 1.1E-14 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 SUPERFAMILY SSF88659 92 172 5.61E-16 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 168 2.1E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 Pfam PF04542 Sigma-70 region 2 24 90 1.8E-9 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 Gene3D G3DSA:1.10.10.10 111 170 5.0E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 Gene3D G3DSA:1.10.1740.10 12 110 4.5E-18 T 09-03-2017 UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 15 169 5.5E-45 T 09-03-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_RS13810 aa2a80196679734a1dc17f772521402c 189 SUPERFAMILY SSF88946 11 108 2.71E-16 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 SUPERFAMILY SSF47413 6 52 5.63E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 Gene3D G3DSA:3.40.50.2300 130 229 1.7E-17 T 09-03-2017 UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 SUPERFAMILY SSF53822 128 386 4.32E-50 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 Gene3D G3DSA:1.10.260.40 7 51 4.0E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 Pfam PF13377 Periplasmic binding protein-like domain 226 386 1.4E-30 T 09-03-2017 UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 SMART SM00354 6 77 1.5E-9 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 Gene3D G3DSA:3.40.50.2300 230 386 6.1E-42 T 09-03-2017 UA74_RS17890 dd5765001b2b7ca5ba6f7970f0a167e2 387 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 51 2.0E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS24605 077825d934380fea2747784317815e5f 127 SUPERFAMILY SSF54197 6 115 2.63E-33 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS24605 077825d934380fea2747784317815e5f 127 Pfam PF01230 HIT domain 16 111 8.4E-23 T 09-03-2017 IPR001310 Histidine triad (HIT) protein UA74_RS24605 077825d934380fea2747784317815e5f 127 Gene3D G3DSA:3.30.428.10 2 113 1.3E-34 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS24605 077825d934380fea2747784317815e5f 127 PRINTS PR00332 Histidine triad family signature 9 25 4.5E-16 T 09-03-2017 IPR001310 Histidine triad (HIT) protein UA74_RS24605 077825d934380fea2747784317815e5f 127 PRINTS PR00332 Histidine triad family signature 98 108 4.5E-16 T 09-03-2017 IPR001310 Histidine triad (HIT) protein UA74_RS24605 077825d934380fea2747784317815e5f 127 PRINTS PR00332 Histidine triad family signature 30 48 4.5E-16 T 09-03-2017 IPR001310 Histidine triad (HIT) protein UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 SUPERFAMILY SSF58014 109 197 9.94E-16 T 09-03-2017 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 Hamap MF_01151 Protein GrpE [grpE]. 5 253 16.373 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 130 146 1.0E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 205 220 1.0E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 232 251 1.0E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 158 173 1.0E-22 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 Gene3D G3DSA:2.30.22.10 197 253 1.2E-19 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 SUPERFAMILY SSF51064 199 253 7.06E-15 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 ProSitePatterns PS01071 grpE protein signature. 208 251 - T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 Pfam PF01025 GrpE 111 252 5.3E-31 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29875 5fe00caf5579465d0137fa682572eb8f 291 Gene3D G3DSA:3.90.20.20 107 189 5.4E-17 T 09-03-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 Gene3D G3DSA:3.50.50.60 4 181 4.6E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 Gene3D G3DSA:3.50.50.60 281 324 4.6E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 Pfam PF04820 Tryptophan halogenase 97 385 4.4E-24 T 09-03-2017 IPR006905 Tryptophan halogenase UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 Pfam PF04820 Tryptophan halogenase 6 90 7.5E-13 T 09-03-2017 IPR006905 Tryptophan halogenase UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 SUPERFAMILY SSF51905 5 176 5.28E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 SUPERFAMILY SSF51905 276 366 5.28E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 6.3E-8 T 09-03-2017 UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 6.3E-8 T 09-03-2017 UA74_RS10945 8b28c74f59048f0db9c3330109ef39a3 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 6.3E-8 T 09-03-2017 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF00698 Acyl transferase domain 531 791 1.6E-37 T 09-03-2017 IPR014043 Acyl transferase UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF47336 967 1039 1.44E-19 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:1.10.1200.10 962 1044 5.9E-26 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 260 1.0E-67 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 269 386 3.9E-39 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 389 498 1.4E-19 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SMART SM00825 Beta-ketoacyl synthase 13 438 7.0E-170 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.40.366.10 525 646 5.5E-59 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.40.366.10 709 819 5.5E-59 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SMART SM00823 Phosphopantetheine attachment site 974 1043 2.3E-6 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 ProSitePatterns PS00012 Phosphopantetheine attachment site. 998 1013 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 174 190 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.40.47.10 13 272 8.5E-77 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 531 850 2.3E-73 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF52151 528 652 3.66E-54 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF52151 711 810 3.66E-54 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF00550 Phosphopantetheine attachment site 976 1039 2.7E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF53901 413 434 2.21E-81 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF53901 10 127 2.21E-81 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF53901 157 382 2.21E-81 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS06590 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.40.47.10 273 438 8.9E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17895 460287a429b443860613bb5ec154258d 690 Gene3D G3DSA:1.50.10.10 153 308 1.7E-10 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS17895 460287a429b443860613bb5ec154258d 690 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 39 566 3.9E-123 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 UA74_RS17895 460287a429b443860613bb5ec154258d 690 SUPERFAMILY SSF48208 93 393 4.17E-20 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS22650 94063f038b0920e598e4460b39c2399b 250 SUPERFAMILY SSF51735 2 192 3.57E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22650 94063f038b0920e598e4460b39c2399b 250 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 169 7.1E-22 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS22650 94063f038b0920e598e4460b39c2399b 250 Gene3D G3DSA:3.40.50.720 2 208 6.9E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 Pfam PF02983 Alpha-lytic protease prodomain 111 171 3.9E-12 T 09-03-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 PIRSF PIRSF001134 1 375 2.7E-123 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 Gene3D G3DSA:3.30.300.50 29 108 2.1E-22 T 09-03-2017 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 Gene3D G3DSA:2.40.10.10 270 360 9.8E-31 T 09-03-2017 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 Gene3D G3DSA:3.30.300.50 110 181 4.5E-18 T 09-03-2017 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 SUPERFAMILY SSF50494 196 367 2.1E-36 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 213 227 3.8E-43 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 274 294 3.8E-43 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 314 337 3.8E-43 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 295 312 3.8E-43 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 338 352 3.8E-43 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 Gene3D G3DSA:2.40.10.10 191 268 7.4E-26 T 09-03-2017 UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 323 334 - T 09-03-2017 IPR033116 Serine proteases, trypsin family, serine active site UA74_RS10575 d4d82b86558c89f8595abdfaef3cf5c4 375 Pfam PF00089 Trypsin 214 365 1.8E-9 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 SMART SM00267 245 417 3.8E-27 T 09-03-2017 IPR000160 GGDEF domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 SMART SM00052 427 677 8.9E-22 T 09-03-2017 IPR001633 EAL domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 SUPERFAMILY SSF141868 436 684 2.62E-40 T 09-03-2017 IPR001633 EAL domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 SUPERFAMILY SSF55785 119 243 1.26E-23 T 09-03-2017 IPR000014 PAS domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 SMART SM00091 130 196 1.9E-11 T 09-03-2017 IPR000014 PAS domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 Pfam PF13426 PAS domain 142 244 1.4E-10 T 09-03-2017 IPR000014 PAS domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 Pfam PF00563 EAL domain 437 669 1.7E-41 T 09-03-2017 IPR001633 EAL domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 SMART SM00086 203 245 9.7E-5 T 09-03-2017 IPR001610 PAC motif UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 414 1.3E-24 T 09-03-2017 IPR000160 GGDEF domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 126 251 2.1E-22 T 09-03-2017 IPR000014 PAS domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 Gene3D G3DSA:3.30.70.270 258 421 2.7E-35 T 09-03-2017 UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 Gene3D G3DSA:3.30.450.20 121 243 5.2E-26 T 09-03-2017 UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 SUPERFAMILY SSF55073 261 419 6.83E-30 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 Gene3D G3DSA:3.20.20.450 431 685 5.7E-51 T 09-03-2017 IPR001633 EAL domain UA74_RS06230 3b5ff83f1ce4ece78cb262eaa02915e0 688 Pfam PF00990 Diguanylate cyclase, GGDEF domain 257 411 2.7E-27 T 09-03-2017 IPR000160 GGDEF domain UA74_RS20325 ed6c984dc4e1c34e993bd65b03c59786 289 Pfam PF13460 NAD(P)H-binding 6 185 2.8E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20325 ed6c984dc4e1c34e993bd65b03c59786 289 Gene3D G3DSA:3.40.50.720 2 218 1.1E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20325 ed6c984dc4e1c34e993bd65b03c59786 289 SUPERFAMILY SSF51735 2 240 2.99E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05505 a92f0eab7f94131501dbb8b84059c57a 521 Gene3D G3DSA:1.20.1250.20 282 512 6.6E-11 T 09-03-2017 UA74_RS05505 a92f0eab7f94131501dbb8b84059c57a 521 Pfam PF07690 Major Facilitator Superfamily 37 428 4.8E-41 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS05505 a92f0eab7f94131501dbb8b84059c57a 521 Gene3D G3DSA:1.20.1250.20 18 209 2.2E-26 T 09-03-2017 UA74_RS05505 a92f0eab7f94131501dbb8b84059c57a 521 SUPERFAMILY SSF103473 265 438 1.96E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS05505 a92f0eab7f94131501dbb8b84059c57a 521 SUPERFAMILY SSF103473 1 210 1.96E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS05505 a92f0eab7f94131501dbb8b84059c57a 521 SUPERFAMILY SSF103473 490 516 1.96E-57 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS01495 c3692f6cbb222007e9d01c2d88501f0a 289 SMART SM00530 16 71 7.0E-12 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS01495 c3692f6cbb222007e9d01c2d88501f0a 289 SUPERFAMILY SSF47413 10 71 8.45E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS01495 c3692f6cbb222007e9d01c2d88501f0a 289 Pfam PF13560 Helix-turn-helix domain 12 72 6.2E-12 T 09-03-2017 UA74_RS01495 c3692f6cbb222007e9d01c2d88501f0a 289 Gene3D G3DSA:1.10.260.40 7 70 1.6E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18925 0261bb0c7e0091ef6f27abcc17060b5f 121 SUPERFAMILY SSF54593 3 119 4.95E-17 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS18925 0261bb0c7e0091ef6f27abcc17060b5f 121 Gene3D G3DSA:3.10.180.10 4 119 6.0E-14 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS18925 0261bb0c7e0091ef6f27abcc17060b5f 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 114 2.9E-4 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 Gene3D G3DSA:3.40.50.300 30 270 9.0E-86 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 Hamap MF_00268 Protein RecA [recA]. 8 332 52.706 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 7 327 2.2E-172 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 SMART SM00382 60 231 6.7E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 SUPERFAMILY SSF52540 7 270 1.62E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 Pfam PF00154 recA bacterial DNA recombination protein 10 271 1.6E-142 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 SUPERFAMILY SSF54752 271 329 1.01E-20 T 09-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 Gene3D G3DSA:3.30.250.10 271 329 2.1E-28 T 09-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 ProSitePatterns PS00321 recA signature. 216 224 - T 09-03-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 300 317 1.1E-85 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 130 159 1.1E-85 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 96 125 1.1E-85 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 246 275 1.1E-85 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 213 241 1.1E-85 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS08635 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 168 197 1.1E-85 T 09-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 SUPERFAMILY SSF50494 93 305 2.26E-36 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 Gene3D G3DSA:2.40.10.10 175 303 5.8E-16 T 09-03-2017 UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 251 263 5.1E-8 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 110 125 5.1E-8 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 167 181 5.1E-8 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 SMART SM00020 86 301 2.1E-8 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 Gene3D G3DSA:2.40.10.10 93 174 2.6E-16 T 09-03-2017 UA74_RS09215 7b61e904d0ecd3c07cceda7b41963f4d 369 Pfam PF00089 Trypsin 93 300 1.4E-24 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 807 1048 4.39E-49 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 1655 1845 2.89E-36 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:2.30.38.10 2402 2484 1.0E-26 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:2.30.38.10 1381 1459 7.2E-21 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:2.30.38.10 336 419 3.1E-21 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 3172 3461 6.7E-51 T 09-03-2017 IPR001242 Condensation domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 2719 3014 3.7E-34 T 09-03-2017 IPR001242 Condensation domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 625 919 3.0E-49 T 09-03-2017 IPR001242 Condensation domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 1657 1944 3.0E-46 T 09-03-2017 IPR001242 Condensation domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF47336 525 595 1.57E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.980 1075 1221 7.5E-32 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.980 22 180 7.7E-34 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.980 2105 2248 5.2E-39 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00550 Phosphopantetheine attachment site 2632 2694 3.7E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00550 Phosphopantetheine attachment site 532 595 1.1E-7 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00550 Phosphopantetheine attachment site 1578 1635 4.7E-8 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF47336 2623 2694 3.66E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2240 2251 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1597 1612 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.300.30 427 535 3.0E-26 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.300.30 1466 1576 1.9E-26 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.300.30 2490 2631 3.7E-28 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2127 2518 2.0E-120 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1101 1494 1.6E-115 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 46 453 7.7E-111 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00501 AMP-binding enzyme 1080 1470 2.5E-74 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00501 AMP-binding enzyme 2109 2493 5.9E-89 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00501 AMP-binding enzyme 32 429 4.4E-82 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF56801 2564 2643 1.7E-138 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF56801 2065 2530 1.7E-138 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF56801 1070 1586 4.97E-126 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF56801 21 543 3.92E-126 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SMART SM00823 Phosphopantetheine attachment site 1573 1642 0.098 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SMART SM00823 Phosphopantetheine attachment site 527 599 0.016 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SMART SM00823 Phosphopantetheine attachment site 2630 2701 0.015 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00012 Phosphopantetheine attachment site. 554 569 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 2715 2913 1.22E-27 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 1833 2070 4.45E-41 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 505 7.7E-6 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF13193 AMP-binding enzyme C-terminal domain 1478 1546 2.3E-9 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1213 1224 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF13745 HxxPF-repeated domain 941 1026 6.1E-15 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF47336 1565 1636 4.58E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 3177 3347 6.56E-38 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.980 2249 2400 7.1E-39 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.980 181 328 1.8E-34 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.980 1222 1374 1.1E-38 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 2900 3139 4.11E-31 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:1.10.1200.10 2632 2697 2.2E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:1.10.1200.10 536 600 9.9E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:1.10.1200.10 1577 1638 1.6E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 622 820 1.33E-38 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 3349 3585 2.11E-44 T 09-03-2017 UA74_RS14925 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2657 2672 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS15840 3cbe7f6bbca8d98e0c0ab626f3b56bff 179 Gene3D G3DSA:3.40.630.30 18 149 5.0E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15840 3cbe7f6bbca8d98e0c0ab626f3b56bff 179 Pfam PF00583 Acetyltransferase (GNAT) family 76 140 2.2E-15 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS15840 3cbe7f6bbca8d98e0c0ab626f3b56bff 179 SUPERFAMILY SSF55729 16 146 9.43E-25 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS22760 ba15ebe0ac806153ce5652a4a773cf30 112 Pfam PF12840 Helix-turn-helix domain 10 69 2.5E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22760 ba15ebe0ac806153ce5652a4a773cf30 112 SMART SM00418 11 89 9.9E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22760 ba15ebe0ac806153ce5652a4a773cf30 112 SUPERFAMILY SSF46785 7 101 1.18E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22760 ba15ebe0ac806153ce5652a4a773cf30 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 5.1E-6 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22760 ba15ebe0ac806153ce5652a4a773cf30 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 5.1E-6 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22760 ba15ebe0ac806153ce5652a4a773cf30 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 5.1E-6 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22760 ba15ebe0ac806153ce5652a4a773cf30 112 Gene3D G3DSA:1.10.10.10 4 110 8.1E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23470 513f9794adad5d60c05f4e4fe4fe22ec 189 Pfam PF01872 RibD C-terminal domain 4 179 1.5E-13 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS23470 513f9794adad5d60c05f4e4fe4fe22ec 189 SUPERFAMILY SSF53597 3 186 4.19E-19 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS23470 513f9794adad5d60c05f4e4fe4fe22ec 189 Gene3D G3DSA:3.40.430.10 5 186 3.4E-17 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF52777 13 190 1.33E-43 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Pfam PF00550 Phosphopantetheine attachment site 983 1045 3.1E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 SMART SM00823 Phosphopantetheine attachment site 980 1049 0.0017 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 ProSitePatterns PS00455 Putative AMP-binding domain signature. 619 630 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1004 1019 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:1.10.1200.10 985 1048 3.5E-22 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:3.40.50.980 470 627 6.4E-45 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF47336 973 1046 1.7E-16 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF56801 439 993 1.83E-139 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:3.30.300.30 866 984 2.3E-34 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:3.40.50.980 628 782 2.7E-35 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Pfam PF00501 AMP-binding enzyme 475 871 5.4E-88 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Pfam PF00668 Condensation domain 9 308 3.9E-66 T 09-03-2017 IPR001242 Condensation domain UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Pfam PF13193 AMP-binding enzyme C-terminal domain 879 950 4.9E-8 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF52777 197 443 8.67E-56 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Pfam PF13745 HxxPF-repeated domain 330 421 4.1E-24 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:2.30.38.10 783 861 1.5E-23 T 09-03-2017 UA74_RS17170 ff3efe691493c4e4294824c114b61616 1055 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 496 895 1.0E-120 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Gene3D G3DSA:2.120.10.30 38 477 3.1E-103 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Gene3D G3DSA:2.60.40.670 817 888 4.3E-15 T 09-03-2017 IPR000601 PKD domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Pfam PF00801 PKD domain 823 876 7.0E-10 T 09-03-2017 IPR000601 PKD domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Pfam PF00801 PKD domain 484 553 5.2E-10 T 09-03-2017 IPR000601 PKD domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Gene3D G3DSA:2.60.40.1560 1392 1473 1.8E-4 T 09-03-2017 UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 SUPERFAMILY SSF49299 810 891 3.66E-14 T 09-03-2017 IPR000601 PKD domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Pfam PF07995 Glucose / Sorbosone dehydrogenase 55 308 7.6E-34 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Gene3D G3DSA:2.60.120.260 675 800 4.3E-21 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 SMART SM00089 809 889 9.3E-11 T 09-03-2017 IPR022409 PKD/Chitinase domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 SMART SM00089 477 564 4.3E-14 T 09-03-2017 IPR022409 PKD/Chitinase domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 SMART SM00606 672 801 4.4E-12 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Pfam PF06439 Domain of Unknown Function (DUF1080) 1029 1204 2.4E-28 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 SUPERFAMILY SSF49299 478 563 3.53E-17 T 09-03-2017 IPR000601 PKD domain UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Pfam PF03422 Carbohydrate binding module (family 6) 680 800 2.9E-15 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 SUPERFAMILY SSF50952 38 456 7.45E-30 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 SUPERFAMILY SSF49785 677 799 7.82E-12 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS12750 c119d197d6abc2276ee8ac79e12311b7 1575 Gene3D G3DSA:2.60.40.670 478 563 7.3E-18 T 09-03-2017 IPR000601 PKD domain UA74_RS00865 84038e5cc5015c3768222705f0bacf71 219 Pfam PF02525 Flavodoxin-like fold 1 167 4.7E-21 T 09-03-2017 IPR003680 Flavodoxin-like fold UA74_RS00865 84038e5cc5015c3768222705f0bacf71 219 Gene3D G3DSA:3.40.50.360 1 211 4.2E-33 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS00865 84038e5cc5015c3768222705f0bacf71 219 SUPERFAMILY SSF52218 2 213 2.62E-27 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS00865 84038e5cc5015c3768222705f0bacf71 219 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 206 19.159 T 09-03-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 UA74_RS12195 4e8950c5b1b378acbae13e3acaf74bcc 78 Gene3D G3DSA:3.30.1360.60 3 77 6.0E-27 T 09-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UA74_RS12195 4e8950c5b1b378acbae13e3acaf74bcc 78 SUPERFAMILY SSF55604 6 77 2.48E-21 T 09-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UA74_RS12195 4e8950c5b1b378acbae13e3acaf74bcc 78 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 64 1.0E-15 T 09-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UA74_RS12195 4e8950c5b1b378acbae13e3acaf74bcc 78 Pfam PF00367 phosphotransferase system, EIIB 8 40 5.0E-14 T 09-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UA74_RS15705 8f7d275b0fac98a6cdaf1e2e8f96da2e 243 SUPERFAMILY SSF53056 42 243 4.84E-48 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS15705 8f7d275b0fac98a6cdaf1e2e8f96da2e 243 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 94 101 - T 09-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS15705 8f7d275b0fac98a6cdaf1e2e8f96da2e 243 Gene3D G3DSA:3.40.1050.10 40 243 1.0E-49 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS15705 8f7d275b0fac98a6cdaf1e2e8f96da2e 243 SMART SM00947 82 243 2.2E-42 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS15705 8f7d275b0fac98a6cdaf1e2e8f96da2e 243 Pfam PF00484 Carbonic anhydrase 90 239 7.6E-35 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS05990 5e2d323cecb656041d2ce55d7e0bc9dc 616 Pfam PF00149 Calcineurin-like phosphoesterase 44 211 3.9E-7 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS05990 5e2d323cecb656041d2ce55d7e0bc9dc 616 Gene3D G3DSA:3.60.21.10 40 246 5.1E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS05990 5e2d323cecb656041d2ce55d7e0bc9dc 616 SUPERFAMILY SSF56300 44 280 1.6E-21 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS05990 5e2d323cecb656041d2ce55d7e0bc9dc 616 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 450 609 1.9E-14 T 09-03-2017 UA74_RS05990 5e2d323cecb656041d2ce55d7e0bc9dc 616 Gene3D G3DSA:2.60.120.200 446 610 4.0E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS05990 5e2d323cecb656041d2ce55d7e0bc9dc 616 SUPERFAMILY SSF49899 354 609 2.52E-22 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS10500 c96a3cffaef245c73822d9b7a1906605 461 Pfam PF01467 Cytidylyltransferase-like 331 422 4.9E-14 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_RS10500 c96a3cffaef245c73822d9b7a1906605 461 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 329 393 6.6E-15 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_RS10500 c96a3cffaef245c73822d9b7a1906605 461 Gene3D G3DSA:3.40.1190.20 3 289 9.2E-31 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS10500 c96a3cffaef245c73822d9b7a1906605 461 SUPERFAMILY SSF52374 328 453 8.73E-22 T 09-03-2017 UA74_RS10500 c96a3cffaef245c73822d9b7a1906605 461 SUPERFAMILY SSF53613 4 289 1.37E-26 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS10500 c96a3cffaef245c73822d9b7a1906605 461 Gene3D G3DSA:3.40.50.620 327 447 2.1E-31 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS10500 c96a3cffaef245c73822d9b7a1906605 461 Pfam PF00294 pfkB family carbohydrate kinase 174 292 3.5E-10 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS19905 9a1625efbebb231e6524149d2dc3b53c 279 Gene3D G3DSA:3.20.20.70 1 273 2.5E-90 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS19905 9a1625efbebb231e6524149d2dc3b53c 279 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 270 3.8E-69 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS19905 9a1625efbebb231e6524149d2dc3b53c 279 PIRSF PIRSF001359 1 277 1.6E-76 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS19905 9a1625efbebb231e6524149d2dc3b53c 279 SUPERFAMILY SSF51569 2 273 4.4E-82 T 09-03-2017 UA74_RS19905 9a1625efbebb231e6524149d2dc3b53c 279 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 274 3.4E-84 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS08775 db4f81f8b76361637399f5803b520ff8 239 SUPERFAMILY SSF46689 15 74 9.98E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS08775 db4f81f8b76361637399f5803b520ff8 239 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 191 2.2E-26 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS08775 db4f81f8b76361637399f5803b520ff8 239 Gene3D G3DSA:1.10.357.10 64 200 3.1E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS08775 db4f81f8b76361637399f5803b520ff8 239 SUPERFAMILY SSF48498 82 199 3.43E-22 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS08775 db4f81f8b76361637399f5803b520ff8 239 Gene3D G3DSA:1.10.10.60 14 61 3.5E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS08775 db4f81f8b76361637399f5803b520ff8 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 68 4.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 SUPERFAMILY SSF52172 8 146 1.01E-27 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 Gene3D G3DSA:3.40.50.2300 8 128 7.8E-30 T 09-03-2017 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 SMART SM00421 157 214 4.8E-23 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 Gene3D G3DSA:1.10.10.10 129 221 2.2E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 SMART SM00448 9 122 8.5E-21 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 Pfam PF00072 Response regulator receiver domain 11 122 3.8E-21 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 SUPERFAMILY SSF46894 147 220 5.44E-22 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 214 9.5E-20 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 5.3E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 5.3E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS15385 0cd7c540b8d6fdcbec5d6a06d2f5e171 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 5.3E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS25365 3e7d75072aabddab69500d4805d97e1c 329 Pfam PF00877 NlpC/P60 family 215 305 4.6E-20 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain UA74_RS25365 3e7d75072aabddab69500d4805d97e1c 329 Gene3D G3DSA:3.90.1720.10 198 310 1.5E-37 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain UA74_RS25365 3e7d75072aabddab69500d4805d97e1c 329 SUPERFAMILY SSF54001 197 310 1.03E-35 T 09-03-2017 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF00676 Dehydrogenase E1 component 550 873 7.0E-58 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:3.30.559.10 154 398 3.9E-51 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 432 1275 5.0E-303 T 09-03-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 164 398 2.4E-54 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 SUPERFAMILY SSF52518 923 1134 6.57E-43 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:3.40.50.970 936 1138 1.7E-19 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 SUPERFAMILY SSF52518 463 872 1.12E-83 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 43 3.5E-12 T 09-03-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1133 1276 5.9E-46 T 09-03-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:3.40.50.970 505 875 2.0E-75 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 SUPERFAMILY SSF52777 162 398 4.89E-54 T 09-03-2017 UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 SMART SM00861 935 1128 4.0E-48 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS26470 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF02779 Transketolase, pyrimidine binding domain 935 1127 1.4E-53 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 SUPERFAMILY SSF53244 314 454 1.69E-33 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 115 138 - T 09-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 Gene3D G3DSA:3.40.1190.10 95 311 6.6E-54 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 13 454 1.0E-106 T 09-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 Pfam PF08245 Mur ligase middle domain 117 228 4.3E-19 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 11 457 30.146 T 09-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 SUPERFAMILY SSF51984 8 95 1.57E-14 T 09-03-2017 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 380 8.4E-6 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 Gene3D G3DSA:3.90.190.20 314 454 1.5E-39 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 SUPERFAMILY SSF53623 111 310 2.49E-40 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09715 e367f5de2b9510154e3a10b3882d9e5e 482 Gene3D G3DSA:3.40.50.720 10 94 2.7E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 9.0E-8 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 173 194 9.0E-8 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 PRINTS PR00377 Inositol monophosphatase superfamily signature 88 104 9.0E-8 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 89 101 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 SUPERFAMILY SSF56655 11 261 3.8E-38 T 09-03-2017 UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 Gene3D G3DSA:3.40.190.80 162 262 2.2E-17 T 09-03-2017 UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 Gene3D G3DSA:3.30.540.10 13 138 6.3E-16 T 09-03-2017 UA74_RS27760 d7f4ba006593c71616b5f83712e4063c 269 Pfam PF00459 Inositol monophosphatase family 20 262 2.0E-15 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 46 474 4.2E-151 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 47 172 4.1E-20 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 356 5.1E-22 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 SUPERFAMILY SSF52540 47 209 1.44E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 Pfam PF01926 50S ribosome-binding GTPase 48 162 3.9E-23 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 Pfam PF01926 50S ribosome-binding GTPase 222 340 3.7E-20 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 396 474 3.7E-25 T 09-03-2017 IPR032859 GTPase Der, C-terminal KH-domain-like UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 Gene3D G3DSA:3.40.50.300 46 210 2.3E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 Gene3D G3DSA:3.40.50.300 221 401 1.3E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 SMART SM00382 44 180 0.95 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 SMART SM00382 219 459 0.61 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 PIRSF PIRSF006485 45 482 5.5E-157 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 Hamap MF_00195 GTPase Der [der]. 45 477 34.585 T 09-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 Gene3D G3DSA:3.30.300.20 402 476 3.1E-27 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 223 243 4.7E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 272 287 4.7E-7 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS10155 d347ed8b3afafc56141c78482b385975 484 SUPERFAMILY SSF52540 180 478 5.48E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 SUPERFAMILY SSF55785 180 291 1.71E-7 T 09-03-2017 IPR000014 PAS domain UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 SMART SM00387 394 494 2.0E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 Pfam PF07568 Histidine kinase 300 369 1.8E-22 T 09-03-2017 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 SUPERFAMILY SSF55874 355 493 1.57E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 Pfam PF08448 PAS fold 178 286 7.8E-9 T 09-03-2017 IPR013656 PAS fold-4 UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 Pfam PF13581 Histidine kinase-like ATPase domain 389 468 1.3E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 Pfam PF12282 Signal transduction histidine kinase 4 151 3.6E-54 T 09-03-2017 IPR022066 Signal transduction histidine kinase UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 Gene3D G3DSA:3.30.450.20 178 283 8.3E-8 T 09-03-2017 UA74_RS26630 2be2ce3e016100076e526a218a5bab23 496 Gene3D G3DSA:3.30.565.10 355 494 7.4E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS25810 30c8c7a28c614275bc0447839dbb6d78 178 Pfam PF12802 MarR family 51 111 1.6E-10 T 09-03-2017 UA74_RS25810 30c8c7a28c614275bc0447839dbb6d78 178 Gene3D G3DSA:1.10.10.10 14 164 1.7E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS25810 30c8c7a28c614275bc0447839dbb6d78 178 SMART SM00347 45 148 1.1E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS25810 30c8c7a28c614275bc0447839dbb6d78 178 SUPERFAMILY SSF46785 15 162 6.69E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS30010 cc4a2850c0bb57bf852cf9b39d480832 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.5E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS30010 cc4a2850c0bb57bf852cf9b39d480832 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.2E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS30010 cc4a2850c0bb57bf852cf9b39d480832 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.2E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS30010 cc4a2850c0bb57bf852cf9b39d480832 199 SUPERFAMILY SSF46689 7 90 9.23E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS30010 cc4a2850c0bb57bf852cf9b39d480832 199 Gene3D G3DSA:1.10.357.10 7 196 2.0E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 Gene3D G3DSA:3.40.50.2300 1 148 1.2E-25 T 09-03-2017 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 SMART SM00421 148 205 2.9E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 SMART SM00448 1 120 8.4E-9 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 Pfam PF00072 Response regulator receiver domain 3 108 1.3E-14 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 Gene3D G3DSA:1.10.10.10 149 214 1.5E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 196 3.3E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS14165 0b0f70c32994966fd7f5054159163538 220 SUPERFAMILY SSF52172 1 167 1.49E-19 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS18910 c253b043dbb0c50b7e7ea462effdfd38 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.1E-13 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS18910 c253b043dbb0c50b7e7ea462effdfd38 297 Gene3D G3DSA:3.40.190.10 82 200 3.5E-21 T 09-03-2017 UA74_RS18910 c253b043dbb0c50b7e7ea462effdfd38 297 Gene3D G3DSA:1.10.10.10 1 81 4.2E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18910 c253b043dbb0c50b7e7ea462effdfd38 297 SUPERFAMILY SSF53850 89 296 4.89E-26 T 09-03-2017 UA74_RS18910 c253b043dbb0c50b7e7ea462effdfd38 297 Gene3D G3DSA:3.40.190.10 201 254 1.8E-12 T 09-03-2017 UA74_RS18910 c253b043dbb0c50b7e7ea462effdfd38 297 SUPERFAMILY SSF46785 1 111 1.49E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18910 c253b043dbb0c50b7e7ea462effdfd38 297 Pfam PF03466 LysR substrate binding domain 89 295 2.2E-28 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS21295 2953d7c4de23fee79135f61c68a44e04 273 Pfam PF01551 Peptidase family M23 167 261 1.2E-32 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS21295 2953d7c4de23fee79135f61c68a44e04 273 SUPERFAMILY SSF51261 105 265 9.94E-52 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS21295 2953d7c4de23fee79135f61c68a44e04 273 Gene3D G3DSA:2.70.70.10 120 266 2.2E-48 T 09-03-2017 UA74_RS19550 8a247bbfb851945d4ed2f9412b8f79ea 329 SMART SM00382 29 212 3.8E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS19550 8a247bbfb851945d4ed2f9412b8f79ea 329 Pfam PF00005 ABC transporter 20 164 9.3E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS19550 8a247bbfb851945d4ed2f9412b8f79ea 329 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 1.4E-105 T 09-03-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_RS19550 8a247bbfb851945d4ed2f9412b8f79ea 329 SUPERFAMILY SSF52540 4 225 4.24E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19550 8a247bbfb851945d4ed2f9412b8f79ea 329 Gene3D G3DSA:3.40.50.300 2 229 2.1E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19550 8a247bbfb851945d4ed2f9412b8f79ea 329 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS19550 8a247bbfb851945d4ed2f9412b8f79ea 329 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 4.8E-8 T 09-03-2017 IPR025302 Domain of unknown function DUF4162 UA74_RS20075 c2457ab76a932c29c4dff94936c3e7a1 609 Gene3D G3DSA:3.30.1180.20 183 333 1.6E-45 T 09-03-2017 UA74_RS20075 c2457ab76a932c29c4dff94936c3e7a1 609 Gene3D G3DSA:3.40.50.10440 13 181 3.7E-54 T 09-03-2017 UA74_RS20075 c2457ab76a932c29c4dff94936c3e7a1 609 SUPERFAMILY SSF82549 11 333 1.96E-102 T 09-03-2017 UA74_RS20075 c2457ab76a932c29c4dff94936c3e7a1 609 SMART SM01120 428 604 8.2E-52 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS20075 c2457ab76a932c29c4dff94936c3e7a1 609 SUPERFAMILY SSF101473 402 605 1.44E-41 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS20075 c2457ab76a932c29c4dff94936c3e7a1 609 Pfam PF02733 Dak1 domain 18 330 5.6E-106 T 09-03-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS20075 c2457ab76a932c29c4dff94936c3e7a1 609 Pfam PF02734 DAK2 domain 429 602 2.0E-42 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS11510 c100392033704c81d4a3e4641758455a 198 Gene3D G3DSA:1.10.10.60 1 46 7.1E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11510 c100392033704c81d4a3e4641758455a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.0E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS11510 c100392033704c81d4a3e4641758455a 198 SUPERFAMILY SSF48498 81 188 4.45E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS11510 c100392033704c81d4a3e4641758455a 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS11510 c100392033704c81d4a3e4641758455a 198 SUPERFAMILY SSF46689 1 75 1.95E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11510 c100392033704c81d4a3e4641758455a 198 Gene3D G3DSA:1.10.10.60 47 76 7.2E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11510 c100392033704c81d4a3e4641758455a 198 Gene3D G3DSA:1.10.357.10 96 185 2.9E-8 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS11510 c100392033704c81d4a3e4641758455a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS11510 c100392033704c81d4a3e4641758455a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS07875 7f7199200fdb761a1cc0448a83500743 202 Gene3D G3DSA:3.40.50.360 2 198 7.1E-16 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS07875 7f7199200fdb761a1cc0448a83500743 202 SUPERFAMILY SSF52218 3 198 1.1E-24 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS07875 7f7199200fdb761a1cc0448a83500743 202 Pfam PF03358 NADPH-dependent FMN reductase 5 156 1.2E-19 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 15 322 7.4E-87 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 16 323 36.263 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 SUPERFAMILY SSF53335 16 126 1.17E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 SUPERFAMILY SSF53335 228 323 1.17E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 Gene3D G3DSA:1.10.150.170 126 230 5.1E-35 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 Gene3D G3DSA:3.40.50.150 231 325 4.4E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 Gene3D G3DSA:3.40.50.150 16 123 4.4E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 Pfam PF01795 MraW methylase family 14 322 2.3E-106 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 SUPERFAMILY SSF81799 127 228 2.09E-32 T 09-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09680 2008c2daabe5cd0bb4e71a0c1b184b32 328 PIRSF PIRSF004486 11 324 1.2E-95 T 09-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS24695 e68aa41871cf7a604e03b39e3ad1b478 116 SUPERFAMILY SSF52038 22 103 1.44E-18 T 09-03-2017 IPR000468 Barstar (barnase inhibitor) UA74_RS24695 e68aa41871cf7a604e03b39e3ad1b478 116 Gene3D G3DSA:3.30.370.10 21 102 3.2E-18 T 09-03-2017 IPR000468 Barstar (barnase inhibitor) UA74_RS24695 e68aa41871cf7a604e03b39e3ad1b478 116 Pfam PF01337 Barstar (barnase inhibitor) 23 101 1.5E-17 T 09-03-2017 IPR000468 Barstar (barnase inhibitor) UA74_RS02970 c5d88844e02fbca46592d8b299cf63a7 84 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 8.7E-21 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02970 c5d88844e02fbca46592d8b299cf63a7 84 Gene3D G3DSA:1.10.287.310 7 68 7.2E-30 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02970 c5d88844e02fbca46592d8b299cf63a7 84 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.434 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02970 c5d88844e02fbca46592d8b299cf63a7 84 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 09-03-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02970 c5d88844e02fbca46592d8b299cf63a7 84 Pfam PF00831 Ribosomal L29 protein 8 64 6.1E-25 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02970 c5d88844e02fbca46592d8b299cf63a7 84 SUPERFAMILY SSF46561 6 67 1.07E-22 T 09-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 SUPERFAMILY SSF52540 30 219 3.58E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 Gene3D G3DSA:1.20.272.10 243 362 2.2E-16 T 09-03-2017 UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 SMART SM00382 34 178 5.4E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 360 1.2E-111 T 09-03-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 362 4.9E-13 T 09-03-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 Gene3D G3DSA:1.10.8.60 165 242 9.8E-20 T 09-03-2017 UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 Pfam PF13177 DNA polymerase III, delta subunit 17 175 1.6E-38 T 09-03-2017 UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 Gene3D G3DSA:3.40.50.300 12 164 5.2E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01000 cfc9a96784adf9734a77a19f93e1c42b 739 SUPERFAMILY SSF48019 244 361 5.95E-21 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 ProSitePatterns PS00012 Phosphopantetheine attachment site. 543 558 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:2.30.38.10 317 394 8.1E-18 T 09-03-2017 UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:3.40.50.980 7 170 2.1E-23 T 09-03-2017 UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:1.10.1200.10 523 585 3.8E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:3.30.300.30 400 522 4.2E-26 T 09-03-2017 UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Pfam PF00501 AMP-binding enzyme 14 404 6.2E-59 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 SUPERFAMILY SSF56801 6 528 9.29E-102 T 09-03-2017 UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:3.40.50.980 183 316 1.6E-23 T 09-03-2017 UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Pfam PF00550 Phosphopantetheine attachment site 522 584 9.2E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 489 4.8E-8 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS05205 0d829dc5192fa8a15647d064d0f86616 588 SUPERFAMILY SSF47336 516 586 7.33E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14410 c0c33500f6ca69194895e911d203a482 334 SUPERFAMILY SSF53335 22 215 4.14E-13 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14410 c0c33500f6ca69194895e911d203a482 334 Gene3D G3DSA:3.40.50.150 68 213 5.2E-9 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14410 c0c33500f6ca69194895e911d203a482 334 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 50 324 1.5E-83 T 09-03-2017 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 UA74_RS15370 8fc900e5ac667f53cc0d250ec6e8f1e8 288 SUPERFAMILY SSF103481 171 272 1.57E-14 T 09-03-2017 UA74_RS15370 8fc900e5ac667f53cc0d250ec6e8f1e8 288 SUPERFAMILY SSF103481 38 128 6.54E-9 T 09-03-2017 UA74_RS15370 8fc900e5ac667f53cc0d250ec6e8f1e8 288 Pfam PF00892 EamA-like transporter family 4 125 2.5E-9 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS15370 8fc900e5ac667f53cc0d250ec6e8f1e8 288 Pfam PF00892 EamA-like transporter family 136 268 1.3E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 SUPERFAMILY SSF81923 3 144 2.75E-32 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 321 3.0E-13 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 797 5.6E-24 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 3.8E-17 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.3E-18 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:3.40.50.300 702 730 9.3E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:3.40.50.300 494 667 9.3E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 SUPERFAMILY SSF52540 167 471 5.62E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF02151 UvrB/uvrC motif 421 453 5.5E-8 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:3.40.50.300 167 347 3.5E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:1.10.1780.10 1 143 1.3E-53 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 7.5E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 7.5E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 7.5E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 7.5E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 SUPERFAMILY SSF52540 490 801 4.51E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 09-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 SMART SM00382 204 349 1.3E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 SMART SM00382 541 720 5.7E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:1.10.8.60 731 804 7.7E-28 T 09-03-2017 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 SMART SM01086 719 815 5.1E-32 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:1.10.8.60 349 432 9.5E-35 T 09-03-2017 UA74_RS01595 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF07724 AAA domain (Cdc48 subfamily) 540 713 6.2E-51 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 SUPERFAMILY SSF56317 1 256 2.22E-60 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 SUPERFAMILY SSF52402 292 557 4.44E-72 T 09-03-2017 UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 TIGRFAM TIGR00552 nadE: NAD+ synthetase 305 552 1.2E-55 T 09-03-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Gene3D G3DSA:3.60.110.10 3 256 1.9E-58 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Pfam PF02540 NAD synthase 302 549 7.5E-69 T 09-03-2017 IPR022310 NAD/GMP synthase UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 09-03-2017 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Gene3D G3DSA:3.40.50.620 291 556 3.1E-74 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 PIRSF PIRSF006630 1 577 2.5E-202 T 09-03-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 UA74_RS25315 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Pfam PF00795 Carbon-nitrogen hydrolase 6 250 8.6E-28 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 Gene3D G3DSA:3.40.50.200 148 398 2.9E-65 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 Gene3D G3DSA:3.40.50.200 546 654 2.9E-65 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 SUPERFAMILY SSF52743 109 386 3.93E-63 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 SUPERFAMILY SSF52743 545 656 3.93E-63 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 Gene3D G3DSA:3.50.30.30 414 529 2.5E-4 T 09-03-2017 UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 590 600 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 589 605 1.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 162 181 1.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 239 252 1.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 167 178 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 243 253 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 Pfam PF00082 Subtilase family 162 626 3.9E-40 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS26110 e8f284d448beada72901b340d5c94ec6 1092 Pfam PF02225 PA domain 425 516 8.9E-6 T 09-03-2017 IPR003137 PA domain UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 7.5E-10 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 7.5E-10 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 7.5E-10 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 7.5E-10 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 144 174 - T 09-03-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 SMART SM01130 12 312 2.8E-78 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 SUPERFAMILY SSF51569 14 313 8.27E-73 T 09-03-2017 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 Gene3D G3DSA:3.20.20.70 15 313 3.4E-81 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 Pfam PF00701 Dihydrodipicolinate synthetase family 15 309 1.4E-48 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS10175 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PIRSF PIRSF001365 14 317 4.1E-69 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 09-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:1.10.286.20 191 234 2.5E-18 T 09-03-2017 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 Hamap MF_00050 Elongation factor Ts [tsf]. 1 272 63.792 T 09-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:3.30.479.20 58 141 4.4E-14 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:3.30.479.20 145 186 1.6E-21 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:3.30.479.20 235 270 1.6E-21 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 271 2.0E-75 T 09-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 Pfam PF00889 Elongation factor TS 67 271 1.4E-61 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 SUPERFAMILY SSF54713 58 88 9.45E-39 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 SUPERFAMILY SSF54713 174 270 9.45E-39 T 09-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 09-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 SUPERFAMILY SSF46934 3 56 2.66E-16 T 09-03-2017 IPR009060 UBA-like GO:0005515 UA74_RS09040 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:1.10.8.10 3 55 7.0E-24 T 09-03-2017 UA74_RS14050 24591c81d7a7476d74038a5ad49c7be7 341 SUPERFAMILY SSF161098 106 176 1.27E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS14050 24591c81d7a7476d74038a5ad49c7be7 341 SUPERFAMILY SSF161098 204 327 1.27E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS14050 24591c81d7a7476d74038a5ad49c7be7 341 Gene3D G3DSA:1.10.3720.10 105 336 7.4E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS14050 24591c81d7a7476d74038a5ad49c7be7 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 339 6.5E-40 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS16025 a490d15e031633bcdca81dbbcc6c608b 402 SUPERFAMILY SSF116734 7 188 1.06E-22 T 09-03-2017 UA74_RS16025 a490d15e031633bcdca81dbbcc6c608b 402 SUPERFAMILY SSF116734 223 396 5.89E-18 T 09-03-2017 UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SMART SM00606 929 1068 3.7E-13 T 09-03-2017 IPR006584 Cellulose binding, type IV GO:0030246 UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SMART SM00089 738 824 1.1E-13 T 09-03-2017 IPR022409 PKD/Chitinase domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SMART SM00089 1079 1160 1.6E-13 T 09-03-2017 IPR022409 PKD/Chitinase domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF50952 690 711 1.12E-16 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF50952 279 565 1.12E-16 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF50952 616 659 1.12E-16 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF49299 736 823 3.14E-17 T 09-03-2017 IPR000601 PKD domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF06283 Trehalose utilisation 48 264 1.6E-75 T 09-03-2017 IPR029010 ThuA-like domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.120.10.30 274 737 7.1E-91 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.60.40.670 1083 1159 1.6E-16 T 09-03-2017 IPR000601 PKD domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF52317 45 271 1.03E-44 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.60.120.260 933 1068 1.0E-28 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.60.40.670 738 824 1.1E-18 T 09-03-2017 IPR000601 PKD domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF49299 1054 1159 1.83E-14 T 09-03-2017 IPR000601 PKD domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF03422 Carbohydrate binding module (family 6) 946 1067 6.8E-13 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF49785 933 1066 2.04E-17 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF00801 PKD domain 753 808 1.2E-10 T 09-03-2017 IPR000601 PKD domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF00801 PKD domain 1083 1148 1.4E-8 T 09-03-2017 IPR000601 PKD domain UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:3.40.50.880 43 273 1.0E-40 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS13955 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF07995 Glucose / Sorbosone dehydrogenase 291 551 5.0E-30 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 SUPERFAMILY SSF53901 3 281 9.02E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Pfam PF02803 Thiolase, C-terminal domain 283 404 2.8E-47 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 2.3E-134 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Gene3D G3DSA:3.40.47.10 4 125 1.9E-57 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Gene3D G3DSA:3.40.47.10 210 288 1.9E-57 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 PIRSF PIRSF000429 1 406 1.4E-124 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Gene3D G3DSA:3.40.47.10 170 209 2.6E-56 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Gene3D G3DSA:3.40.47.10 289 404 2.6E-56 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 2.1E-57 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 UA74_RS03850 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 SUPERFAMILY SSF53901 283 404 8.89E-44 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS08185 f7d8763158fa5a0012b219cdd9a790c5 471 Gene3D G3DSA:3.40.50.1820 167 325 4.4E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08185 f7d8763158fa5a0012b219cdd9a790c5 471 Gene3D G3DSA:3.40.50.1820 360 470 4.4E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08185 f7d8763158fa5a0012b219cdd9a790c5 471 PIRSF PIRSF016521 43 471 1.5E-64 T 09-03-2017 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 UA74_RS08185 f7d8763158fa5a0012b219cdd9a790c5 471 SUPERFAMILY SSF53474 375 470 1.2E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08185 f7d8763158fa5a0012b219cdd9a790c5 471 SUPERFAMILY SSF53474 106 341 1.2E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08185 f7d8763158fa5a0012b219cdd9a790c5 471 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 238 470 2.2E-29 T 09-03-2017 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal Reactome: R-HSA-75105 UA74_RS08185 f7d8763158fa5a0012b219cdd9a790c5 471 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 67 171 3.1E-17 T 09-03-2017 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 Gene3D G3DSA:3.90.550.10 5 188 3.6E-25 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 Gene3D G3DSA:3.40.50.1000 372 534 6.6E-46 T 09-03-2017 IPR023214 HAD-like domain UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 SUPERFAMILY SSF56784 376 531 1.16E-40 T 09-03-2017 IPR023214 HAD-like domain UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 SUPERFAMILY SSF53448 2 200 5.7E-32 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 Pfam PF13242 HAD-hyrolase-like 471 540 5.8E-14 T 09-03-2017 UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 380 518 2.0E-26 T 09-03-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 379 516 4.5E-30 T 09-03-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 UA74_RS10485 8b7f266505938d0a9cb34a595dda5a20 551 Pfam PF00535 Glycosyl transferase family 2 5 101 1.4E-12 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS09640 0cf7be89f928ba44561eadf673ffd7a9 277 Gene3D G3DSA:3.40.50.300 2 258 1.5E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09640 0cf7be89f928ba44561eadf673ffd7a9 277 SUPERFAMILY SSF52540 2 253 7.04E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09640 0cf7be89f928ba44561eadf673ffd7a9 277 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 226 1.5E-39 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain UA74_RS00200 ea2dde65e4bb65239a744db0b94abd4f 437 SMART SM00530 12 67 1.3E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS00200 ea2dde65e4bb65239a744db0b94abd4f 437 Gene3D G3DSA:1.25.40.10 192 305 8.4E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS00200 ea2dde65e4bb65239a744db0b94abd4f 437 Gene3D G3DSA:1.10.260.40 15 63 4.3E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS00200 ea2dde65e4bb65239a744db0b94abd4f 437 Pfam PF01381 Helix-turn-helix 15 63 6.4E-8 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS00200 ea2dde65e4bb65239a744db0b94abd4f 437 SUPERFAMILY SSF47413 13 65 5.35E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS00200 ea2dde65e4bb65239a744db0b94abd4f 437 SUPERFAMILY SSF48452 191 307 6.51E-11 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS17125 7574c2891486eb4a5e53ec9d0c7ce7c1 181 SUPERFAMILY SSF55811 12 130 4.74E-24 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS17125 7574c2891486eb4a5e53ec9d0c7ce7c1 181 PRINTS PR00502 NUDIX hydrolase family signature 27 41 3.5E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS17125 7574c2891486eb4a5e53ec9d0c7ce7c1 181 PRINTS PR00502 NUDIX hydrolase family signature 41 56 3.5E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS17125 7574c2891486eb4a5e53ec9d0c7ce7c1 181 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS17125 7574c2891486eb4a5e53ec9d0c7ce7c1 181 Gene3D G3DSA:3.90.79.10 1 127 3.6E-33 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS17125 7574c2891486eb4a5e53ec9d0c7ce7c1 181 Pfam PF00293 NUDIX domain 1 123 1.8E-16 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS14375 15380d70c1d0e222f8bf36ee15828bb4 293 Gene3D G3DSA:3.40.830.10 35 292 4.1E-75 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 UA74_RS14375 15380d70c1d0e222f8bf36ee15828bb4 293 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 58 278 6.8E-34 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 UA74_RS14375 15380d70c1d0e222f8bf36ee15828bb4 293 PIRSF PIRSF006157 34 293 1.9E-71 T 09-03-2017 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 UA74_RS14375 15380d70c1d0e222f8bf36ee15828bb4 293 SUPERFAMILY SSF53213 38 291 2.75E-70 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 UA74_RS07340 ecec5c9f161b903ab1377ea01a41af98 99 SUPERFAMILY SSF89957 1 97 7.06E-29 T 09-03-2017 IPR029756 MTH1187/YkoF-like UA74_RS07340 ecec5c9f161b903ab1377ea01a41af98 99 Pfam PF01910 Thiamine-binding protein 4 93 3.8E-31 T 09-03-2017 IPR002767 Thiamine-binding protein UA74_RS07340 ecec5c9f161b903ab1377ea01a41af98 99 Gene3D G3DSA:3.30.70.930 1 97 2.2E-35 T 09-03-2017 IPR029756 MTH1187/YkoF-like UA74_RS07340 ecec5c9f161b903ab1377ea01a41af98 99 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 95 5.5E-18 T 09-03-2017 IPR002767 Thiamine-binding protein UA74_RS11745 3b995735661c44199c92fd8de40a62d3 384 Pfam PF13672 Protein phosphatase 2C 108 330 1.5E-13 T 09-03-2017 UA74_RS11745 3b995735661c44199c92fd8de40a62d3 384 SMART SM00332 87 373 9.7E-6 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS11745 3b995735661c44199c92fd8de40a62d3 384 SUPERFAMILY SSF81606 97 229 3.14E-35 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS11745 3b995735661c44199c92fd8de40a62d3 384 SUPERFAMILY SSF81606 263 375 3.14E-35 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS11745 3b995735661c44199c92fd8de40a62d3 384 Gene3D G3DSA:3.60.40.10 97 221 3.0E-47 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS11745 3b995735661c44199c92fd8de40a62d3 384 Gene3D G3DSA:3.60.40.10 257 375 3.0E-47 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 Pfam PF02142 MGS-like domain 29 142 1.1E-24 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 SMART SM00798 148 469 4.2E-165 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 SUPERFAMILY SSF53927 226 534 2.61E-110 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 PIRSF PIRSF000414 12 534 3.9E-187 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 Gene3D G3DSA:3.40.140.20 257 376 2.0E-43 T 09-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 18 534 2.1E-161 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 SUPERFAMILY SSF52335 17 205 4.06E-62 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 SMART SM00851 29 143 1.2E-46 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 17 534 40.31 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 Gene3D G3DSA:3.40.50.1380 16 198 5.1E-75 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 Gene3D G3DSA:3.40.140.20 383 523 2.7E-48 T 09-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS27835 a7b8cd2d8472483a0789a08ce80c8f04 534 Pfam PF01808 AICARFT/IMPCHase bienzyme 148 468 1.2E-108 T 09-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 SUPERFAMILY SSF51569 3 305 7.01E-63 T 09-03-2017 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 SMART SM01130 5 304 4.6E-62 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 Pfam PF00701 Dihydrodipicolinate synthetase family 6 302 4.9E-35 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 6.9E-7 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 6.9E-7 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 136 153 6.9E-7 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 Gene3D G3DSA:3.20.20.70 6 306 8.0E-75 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS24210 13d4759067a4d7f0d4f74989792725cd 306 PIRSF PIRSF001365 1 305 1.4E-58 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS17205 fe83126ba99bb3ba3766e98d1ed4ed02 254 SUPERFAMILY SSF55729 46 242 5.68E-19 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS17205 fe83126ba99bb3ba3766e98d1ed4ed02 254 Gene3D G3DSA:3.40.630.30 107 242 3.5E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS17205 fe83126ba99bb3ba3766e98d1ed4ed02 254 Pfam PF00583 Acetyltransferase (GNAT) family 172 237 1.2E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS14730 ba79b47a64967804254d50999f9f46db 338 SUPERFAMILY SSF51430 2 307 4.85E-82 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS14730 ba79b47a64967804254d50999f9f46db 338 PRINTS PR00069 Aldo-keto reductase signature 105 123 6.8E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS14730 ba79b47a64967804254d50999f9f46db 338 PRINTS PR00069 Aldo-keto reductase signature 42 66 6.8E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS14730 ba79b47a64967804254d50999f9f46db 338 PRINTS PR00069 Aldo-keto reductase signature 136 153 6.8E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS14730 ba79b47a64967804254d50999f9f46db 338 Pfam PF00248 Aldo/keto reductase family 15 307 3.4E-63 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS14730 ba79b47a64967804254d50999f9f46db 338 Gene3D G3DSA:3.20.20.100 3 308 4.3E-81 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 SUPERFAMILY SSF51055 482 533 3.34E-15 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 SMART SM00495 485 530 2.1E-16 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 SMART SM00636 54 444 3.2E-121 T 09-03-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 Pfam PF00704 Glycosyl hydrolases family 18 56 444 7.2E-79 T 09-03-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 ProSitePatterns PS01095 Chitinases family 18 active site. 212 220 - T 09-03-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 Gene3D G3DSA:3.20.20.80 50 351 2.3E-98 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 Gene3D G3DSA:3.20.20.80 421 456 2.3E-98 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 Gene3D G3DSA:2.10.10.20 483 530 8.6E-20 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 SUPERFAMILY SSF51445 414 449 1.15E-88 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 SUPERFAMILY SSF51445 52 348 1.15E-88 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 SUPERFAMILY SSF54556 350 416 1.5E-11 T 09-03-2017 IPR029070 Chitinase insertion domain UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 Pfam PF02839 Carbohydrate binding domain 485 527 1.8E-11 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS27455 be5a3b90631c3d4b165cb3350af9a1ae 533 Gene3D G3DSA:3.10.50.10 352 416 8.9E-23 T 09-03-2017 IPR029070 Chitinase insertion domain UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 330 39.6 T 09-03-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 Pfam PF06827 Zinc finger found in FPG and IleRS 302 330 8.5E-5 T 09-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 Gene3D G3DSA:3.20.190.10 2 67 6.9E-38 T 09-03-2017 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 Gene3D G3DSA:3.20.190.10 118 176 6.9E-38 T 09-03-2017 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 SUPERFAMILY SSF81624 2 67 2.36E-33 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 SUPERFAMILY SSF81624 119 198 2.36E-33 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 SMART SM00898 2 170 1.5E-47 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 168 5.6E-34 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 SMART SM01232 189 281 8.7E-41 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 Gene3D G3DSA:1.10.8.50 190 330 3.1E-44 T 09-03-2017 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 329 2.0E-81 T 09-03-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 189 275 1.3E-21 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 SUPERFAMILY SSF57716 281 330 2.02E-14 T 09-03-2017 UA74_RS25760 7fb6a418969eb812a1f74319dc4d230c 337 SUPERFAMILY SSF46946 188 278 1.91E-25 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 Gene3D G3DSA:3.40.440.10 194 265 1.7E-64 T 09-03-2017 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 Gene3D G3DSA:3.40.440.10 2 94 1.7E-64 T 09-03-2017 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 SUPERFAMILY SSF52540 1 423 5.52E-168 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 Gene3D G3DSA:3.90.170.10 266 424 3.2E-69 T 09-03-2017 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 200.595 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 424 7.4E-163 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 SMART SM00788 3 423 1.8E-275 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 Pfam PF00709 Adenylosuccinate synthetase 4 422 3.2E-174 T 09-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 09-03-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 09-03-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_RS29545 1aa4531262724f37105e030f9392fb03 430 Gene3D G3DSA:1.10.300.10 102 193 1.9E-35 T 09-03-2017 UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 SUPERFAMILY SSF54999 5 100 1.31E-36 T 09-03-2017 IPR027486 Ribosomal protein S10 domain UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 7.9E-46 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 09-03-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.593 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.9E-34 T 09-03-2017 IPR027486 Ribosomal protein S10 domain UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 09-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 Gene3D G3DSA:3.30.70.600 4 100 1.6E-42 T 09-03-2017 IPR027486 Ribosomal protein S10 domain UA74_RS02925 18e8aee56088f06c8b312f3fdbfff1cf 101 SMART SM01403 7 101 2.8E-55 T 09-03-2017 IPR027486 Ribosomal protein S10 domain UA74_RS11580 ad2a8e345e7cce9a3e72f98138f3a3f3 298 SUPERFAMILY SSF103481 31 133 6.15E-12 T 09-03-2017 UA74_RS11580 ad2a8e345e7cce9a3e72f98138f3a3f3 298 Pfam PF00892 EamA-like transporter family 4 130 1.9E-16 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS11580 ad2a8e345e7cce9a3e72f98138f3a3f3 298 Pfam PF00892 EamA-like transporter family 141 275 2.0E-14 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS11580 ad2a8e345e7cce9a3e72f98138f3a3f3 298 SUPERFAMILY SSF103481 186 278 3.27E-10 T 09-03-2017 UA74_RS12050 16829492fe2622bc5b44211d8ef10fda 348 Gene3D G3DSA:2.70.50.50 32 224 1.2E-47 T 09-03-2017 UA74_RS12050 16829492fe2622bc5b44211d8ef10fda 348 SUPERFAMILY SSF49384 246 347 3.28E-30 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS12050 16829492fe2622bc5b44211d8ef10fda 348 Pfam PF00553 Cellulose binding domain 247 347 1.4E-28 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS12050 16829492fe2622bc5b44211d8ef10fda 348 SMART SM00637 247 347 1.2E-37 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS12050 16829492fe2622bc5b44211d8ef10fda 348 SUPERFAMILY SSF81296 32 224 8.26E-45 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS12050 16829492fe2622bc5b44211d8ef10fda 348 Gene3D G3DSA:2.60.40.290 246 348 7.6E-34 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS12050 16829492fe2622bc5b44211d8ef10fda 348 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 221 4.7E-42 T 09-03-2017 IPR004302 Chitin-binding protein, N-terminal UA74_RS24415 ba82601cc71197631cd3b5d0c28a6713 273 SUPERFAMILY SSF47413 29 80 8.28E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24415 ba82601cc71197631cd3b5d0c28a6713 273 Pfam PF13560 Helix-turn-helix domain 5 82 1.4E-14 T 09-03-2017 UA74_RS24415 ba82601cc71197631cd3b5d0c28a6713 273 Gene3D G3DSA:1.10.260.40 4 80 1.5E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24415 ba82601cc71197631cd3b5d0c28a6713 273 SMART SM00530 9 81 6.4E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS08490 7ce5dbac6315c0193937b7414b3423bf 247 SUPERFAMILY SSF53335 14 222 3.04E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS08490 7ce5dbac6315c0193937b7414b3423bf 247 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 38 191 1.9E-25 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS08490 7ce5dbac6315c0193937b7414b3423bf 247 Gene3D G3DSA:3.40.50.150 24 219 1.4E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS08490 7ce5dbac6315c0193937b7414b3423bf 247 Pfam PF05050 Methyltransferase FkbM domain 41 215 6.9E-18 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS29610 389be387d69d736e0dbff13a9286ddbd 385 Pfam PF07690 Major Facilitator Superfamily 4 301 2.2E-28 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS29610 389be387d69d736e0dbff13a9286ddbd 385 SUPERFAMILY SSF103473 2 377 4.19E-45 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS29610 389be387d69d736e0dbff13a9286ddbd 385 Gene3D G3DSA:1.20.1250.20 195 375 2.4E-10 T 09-03-2017 UA74_RS29610 389be387d69d736e0dbff13a9286ddbd 385 Gene3D G3DSA:1.20.1250.20 2 178 1.8E-23 T 09-03-2017 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 131 136 - T 09-03-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 Gene3D G3DSA:2.40.10.10 113 199 2.8E-15 T 09-03-2017 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 Gene3D G3DSA:2.40.10.10 200 291 1.0E-21 T 09-03-2017 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 PRINTS PR00839 V8 serine protease family signature 265 277 2.2E-27 T 09-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 PRINTS PR00839 V8 serine protease family signature 154 166 2.2E-27 T 09-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 PRINTS PR00839 V8 serine protease family signature 95 112 2.2E-27 T 09-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 PRINTS PR00839 V8 serine protease family signature 215 228 2.2E-27 T 09-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 PRINTS PR00839 V8 serine protease family signature 120 137 2.2E-27 T 09-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 PRINTS PR00839 V8 serine protease family signature 248 264 2.2E-27 T 09-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 ProSitePatterns PS00673 Serine proteases, V8 family, serine active site. 254 264 - T 09-03-2017 IPR000126 Serine proteases, V8 family, serine active site GO:0006508|GO:0008236 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 Pfam PF13365 Trypsin-like peptidase domain 120 273 3.7E-10 T 09-03-2017 UA74_RS01125 f2d39f0cbfffafd402200f623269a751 302 SUPERFAMILY SSF50494 86 299 1.71E-31 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 Gene3D G3DSA:3.40.50.1370 1 143 1.4E-48 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 305 38.816 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 148 1.5E-37 T 09-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 SUPERFAMILY SSF53671 1 304 1.3E-92 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 2.4E-17 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 2.4E-17 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 2.4E-17 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 2.4E-17 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 301 3.3E-21 T 09-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.2E-30 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 3.2E-30 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 3.2E-30 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 3.2E-30 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 3.2E-30 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 3.2E-30 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 303 4.9E-87 T 09-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12280 4e0d2695454fdc7df320d36de05499ed 309 Gene3D G3DSA:3.40.50.1370 144 281 4.8E-46 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS25140 e0a8ab374cb91c29353f5c877960fa82 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 09-03-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site UA74_RS25140 e0a8ab374cb91c29353f5c877960fa82 123 Gene3D G3DSA:2.60.300.12 19 112 1.1E-26 T 09-03-2017 IPR000361 FeS cluster biogenesis UA74_RS25140 e0a8ab374cb91c29353f5c877960fa82 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 120 7.3E-18 T 09-03-2017 IPR000361 FeS cluster biogenesis UA74_RS25140 e0a8ab374cb91c29353f5c877960fa82 123 SUPERFAMILY SSF89360 15 110 3.73E-26 T 09-03-2017 IPR000361 FeS cluster biogenesis UA74_RS25140 e0a8ab374cb91c29353f5c877960fa82 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 123 9.7E-34 T 09-03-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 UA74_RS27800 392a504d5e88413f7bcf1a6f08910af3 162 SUPERFAMILY SSF160424 14 151 1.27E-22 T 09-03-2017 IPR006728 Protein of unknown function DUF600 UA74_RS22980 1b409296b25c5f413e6e3d42c0c90214 192 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 190 7.8E-91 T 09-03-2017 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD UA74_RS22980 1b409296b25c5f413e6e3d42c0c90214 192 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 185 5.7E-16 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_RS22980 1b409296b25c5f413e6e3d42c0c90214 192 Gene3D G3DSA:1.10.340.30 17 136 2.2E-11 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS22980 1b409296b25c5f413e6e3d42c0c90214 192 SUPERFAMILY SSF48150 18 148 2.27E-15 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 Gene3D G3DSA:3.40.50.980 4 170 4.7E-23 T 09-03-2017 UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 SUPERFAMILY SSF56801 4 512 3.53E-108 T 09-03-2017 UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 Pfam PF00501 AMP-binding enzyme 13 414 3.9E-70 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 504 2.0E-7 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 Gene3D G3DSA:3.40.50.980 177 324 2.8E-33 T 09-03-2017 UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 Gene3D G3DSA:2.30.38.10 325 404 3.1E-20 T 09-03-2017 UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 Gene3D G3DSA:3.30.300.30 409 512 4.1E-16 T 09-03-2017 UA74_RS17650 c03c89f4bc07bc8159f4779fe6882843 623 Gene3D G3DSA:1.10.1200.10 560 603 6.9E-4 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 Pfam PF13244 Domain of unknown function (DUF4040) 600 665 3.2E-16 T 09-03-2017 IPR025383 Domain of unknown function DUF4040 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 9.1E-32 T 09-03-2017 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 9.1E-32 T 09-03-2017 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 102 122 9.1E-32 T 09-03-2017 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 9.1E-32 T 09-03-2017 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 9.1E-32 T 09-03-2017 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 303 315 9.1E-32 T 09-03-2017 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 Pfam PF00361 Proton-conducting membrane transporter 125 398 2.9E-66 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS19270 98941632aca5d17c1d5ce76a99fc62a6 950 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 784 905 1.3E-30 T 09-03-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein UA74_RS10480 a3bf86af07d68a53a72efa8195a26d7a 541 Pfam PF16861 Carbamoyltransferase C-terminus 371 540 9.1E-63 T 09-03-2017 IPR031730 Carbamoyltransferase, C-terminal UA74_RS10480 a3bf86af07d68a53a72efa8195a26d7a 541 Pfam PF02543 Carbamoyltransferase N-terminus 2 322 1.5E-55 T 09-03-2017 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 UA74_RS10480 a3bf86af07d68a53a72efa8195a26d7a 541 SUPERFAMILY SSF55821 363 538 8.85E-6 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain UA74_RS10480 a3bf86af07d68a53a72efa8195a26d7a 541 SUPERFAMILY SSF53067 1 87 7.77E-18 T 09-03-2017 UA74_RS10480 a3bf86af07d68a53a72efa8195a26d7a 541 SUPERFAMILY SSF53067 121 325 7.77E-18 T 09-03-2017 UA74_RS15210 bab3d99d96505408a33bbd78f87cb591 203 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 23 192 1.3E-21 T 09-03-2017 IPR026588 Choice-of-anchor A domain UA74_RS15470 d13b25ddbe7251890272840a62027ac4 90 SUPERFAMILY SSF53474 4 78 4.84E-6 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15470 d13b25ddbe7251890272840a62027ac4 90 Gene3D G3DSA:3.40.50.1820 9 78 1.2E-9 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15470 d13b25ddbe7251890272840a62027ac4 90 Pfam PF01738 Dienelactone hydrolase family 7 76 2.9E-8 T 09-03-2017 IPR002925 Dienelactone hydrolase GO:0016787 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 SUPERFAMILY SSF53822 61 330 5.1E-73 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 Gene3D G3DSA:3.40.50.2300 174 310 2.3E-41 T 09-03-2017 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 SUPERFAMILY SSF47413 2 59 2.01E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 Gene3D G3DSA:1.10.260.40 2 53 1.0E-26 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 09-03-2017 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.4E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.4E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 Gene3D G3DSA:3.40.50.2300 54 173 6.9E-46 T 09-03-2017 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.7E-19 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 59 313 2.6E-36 T 09-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain UA74_RS30320 fdf88c25b4936c185788280ea0b74af7 340 SMART SM00354 1 71 2.0E-33 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 SMART SM00859 4 136 1.6E-44 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 Gene3D G3DSA:3.40.50.720 1 154 2.0E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 Gene3D G3DSA:3.30.360.10 155 310 1.0E-53 T 09-03-2017 UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 SUPERFAMILY SSF55347 146 310 7.19E-44 T 09-03-2017 UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 313 1.9E-17 T 09-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 SUPERFAMILY SSF51735 3 170 2.77E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 342 1.6E-112 T 09-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 129 5.4E-25 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_RS21695 afe4a3755df4907b3ae9f4031e18fc07 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 38.014 T 09-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 Pfam PF00271 Helicase conserved C-terminal domain 479 588 4.8E-13 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 SUPERFAMILY SSF52540 155 176 4.26E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 SUPERFAMILY SSF52540 203 392 4.26E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 SMART SM00487 156 364 2.3E-28 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 Gene3D G3DSA:3.40.50.300 470 608 4.9E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 SMART SM00490 502 588 5.5E-18 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 Pfam PF00176 SNF2 family N-terminal domain 163 457 1.4E-57 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 SUPERFAMILY SSF52540 394 645 6.05E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15010 9d95d964b9a5b233e56c755e27d4d369 649 Gene3D G3DSA:3.40.50.300 156 347 7.1E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 Gene3D G3DSA:3.20.20.80 4 324 8.5E-97 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 Pfam PF01120 Alpha-L-fucosidase 8 321 3.5E-87 T 09-03-2017 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 119 138 2.3E-21 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 308 330 2.3E-21 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 275 296 2.3E-21 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 74 90 2.3E-21 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 SUPERFAMILY SSF51445 4 325 8.43E-95 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 PIRSF PIRSF001092 2 389 1.3E-110 T 09-03-2017 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51 UA74_RS11915 62ea468670dd466d6a472dacef84955a 426 SMART SM00812 2 364 6.8E-112 T 09-03-2017 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51 UA74_RS22105 67d8ed8e06bf0773f1b1917a96ae5a96 228 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 9 205 8.9E-42 T 09-03-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 UA74_RS22105 67d8ed8e06bf0773f1b1917a96ae5a96 228 Gene3D G3DSA:1.10.3630.10 3 216 7.4E-32 T 09-03-2017 UA74_RS21600 73547ad1265771677232ca550d731439 297 Hamap MF_00361 NAD kinase [nadK]. 3 286 27.823 T 09-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 UA74_RS21600 73547ad1265771677232ca550d731439 297 Gene3D G3DSA:2.60.200.30 148 259 3.1E-37 T 09-03-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 UA74_RS21600 73547ad1265771677232ca550d731439 297 SUPERFAMILY SSF111331 4 292 4.45E-75 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain UA74_RS21600 73547ad1265771677232ca550d731439 297 Pfam PF01513 ATP-NAD kinase 59 270 8.0E-59 T 09-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 UA74_RS21600 73547ad1265771677232ca550d731439 297 Gene3D G3DSA:3.40.50.10330 3 147 2.7E-30 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 UA74_RS00985 54a53e3ca665cc683e2abab4791aefd7 344 Gene3D G3DSA:3.40.50.2300 64 177 1.5E-35 T 09-03-2017 UA74_RS00985 54a53e3ca665cc683e2abab4791aefd7 344 Pfam PF13407 Periplasmic binding protein domain 65 317 7.8E-67 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS00985 54a53e3ca665cc683e2abab4791aefd7 344 Gene3D G3DSA:3.40.50.2300 178 329 8.7E-46 T 09-03-2017 UA74_RS00985 54a53e3ca665cc683e2abab4791aefd7 344 SUPERFAMILY SSF53822 65 339 2.17E-68 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS06445 d91d45055c59072bf35ec4baeb1162f8 100 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 94 7.7E-8 T 09-03-2017 IPR022536 ESX-1 secretion-associated protein EspC UA74_RS06445 d91d45055c59072bf35ec4baeb1162f8 100 Gene3D G3DSA:1.10.287.1060 1 99 1.3E-7 T 09-03-2017 UA74_RS06445 d91d45055c59072bf35ec4baeb1162f8 100 SUPERFAMILY SSF140453 1 96 6.93E-11 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.56.10 3 41 8.1E-16 T 09-03-2017 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.56.10 195 224 8.1E-16 T 09-03-2017 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.50.40.10 241 435 5.7E-76 T 09-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SMART SM00896 767 860 7.7E-40 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 108 860 3.6E-161 T 09-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF46955 443 518 3.11E-12 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 854 38.92 T 09-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:2.40.50.140 113 193 3.5E-37 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:2.40.50.140 45 75 3.5E-37 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF03483 B3/4 domain 252 424 7.9E-62 T 09-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SMART SM00873 252 425 6.1E-78 T 09-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SMART SM00874 441 514 1.8E-18 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF01588 Putative tRNA binding domain 109 181 1.1E-9 T 09-03-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF54991 765 860 1.7E-26 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF03484 tRNA synthetase B5 domain 444 514 5.7E-13 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF03147 Ferredoxin-fold anticodon binding domain 767 860 2.3E-24 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.70.380 769 860 6.5E-29 T 09-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.930.10 529 756 1.7E-61 T 09-03-2017 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF55681 656 755 5.96E-40 T 09-03-2017 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF55681 510 626 5.96E-40 T 09-03-2017 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.56.20 441 518 3.5E-17 T 09-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF56037 239 437 4.45E-65 T 09-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 UA74_RS21725 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF50249 108 232 4.06E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 1.1E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 SMART SM00895 87 210 2.3E-11 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 SUPERFAMILY SSF46785 10 81 3.67E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 Pfam PF07729 FCD domain 91 209 2.1E-18 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 SUPERFAMILY SSF48008 83 215 3.14E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 4.5E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 4.5E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 SMART SM00345 19 77 3.0E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 Gene3D G3DSA:1.20.120.530 80 217 8.4E-24 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS15660 261e8aa37aa599b21b691952ac09de69 223 Gene3D G3DSA:1.10.10.10 4 78 1.6E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18510 2201a81161c13562e6145d00e223b50e 307 Pfam PF05368 NmrA-like family 8 245 2.6E-43 T 09-03-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_RS18510 2201a81161c13562e6145d00e223b50e 307 SUPERFAMILY SSF51735 8 268 1.71E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18510 2201a81161c13562e6145d00e223b50e 307 Gene3D G3DSA:3.40.50.720 6 245 1.0E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 TIGRFAM TIGR01224 hutI: imidazolonepropionase 24 383 5.0E-101 T 09-03-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 SUPERFAMILY SSF51338 11 73 2.7E-9 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 Gene3D G3DSA:2.30.40.10 4 69 1.6E-11 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 Gene3D G3DSA:3.20.20.140 70 363 7.2E-45 T 09-03-2017 UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 SUPERFAMILY SSF51556 59 338 2.94E-68 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 385 41.314 T 09-03-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 SUPERFAMILY SSF51338 321 385 4.37E-13 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS26495 008b3917237355c7b1faf88fba8a03f9 386 Pfam PF01979 Amidohydrolase family 57 366 7.2E-15 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS11380 9362b2a2d67a243981ecec3f763bd879 260 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 83 2.7E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS11380 9362b2a2d67a243981ecec3f763bd879 260 SUPERFAMILY SSF46689 28 93 9.48E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11380 9362b2a2d67a243981ecec3f763bd879 260 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 100 252 1.4E-18 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS11380 9362b2a2d67a243981ecec3f763bd879 260 Gene3D G3DSA:1.10.357.10 27 257 4.3E-53 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS11380 9362b2a2d67a243981ecec3f763bd879 260 SUPERFAMILY SSF48498 105 256 1.1E-23 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS19330 1062defe15b8f0ce78561b26c9b91d6c 298 Pfam PF13803 Domain of unknown function (DUF4184) 1 131 8.8E-28 T 09-03-2017 IPR025238 Protein of unknown function DUF4184 UA74_RS07535 4e79bde52746e563afbdb1beaa75d8de 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 1.9E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS27350 8655e12f8ed37209988676c210487f17 403 ProSitePatterns PS01125 ROK family signature. 218 245 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS27350 8655e12f8ed37209988676c210487f17 403 SUPERFAMILY SSF46785 17 80 1.01E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27350 8655e12f8ed37209988676c210487f17 403 SUPERFAMILY SSF53067 87 396 1.1E-58 T 09-03-2017 UA74_RS27350 8655e12f8ed37209988676c210487f17 403 Gene3D G3DSA:1.10.10.10 21 81 6.4E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27350 8655e12f8ed37209988676c210487f17 403 Pfam PF00480 ROK family 88 395 9.5E-59 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS27350 8655e12f8ed37209988676c210487f17 403 Gene3D G3DSA:3.30.420.40 224 379 6.7E-47 T 09-03-2017 UA74_RS27350 8655e12f8ed37209988676c210487f17 403 Gene3D G3DSA:3.30.420.40 87 223 3.5E-39 T 09-03-2017 UA74_RS10965 c9ea574ad8177b633f89327bf1670170 327 Gene3D G3DSA:3.40.50.720 6 162 1.5E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10965 c9ea574ad8177b633f89327bf1670170 327 SUPERFAMILY SSF51735 6 163 6.81E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10965 c9ea574ad8177b633f89327bf1670170 327 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 1.3E-22 T 09-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 UA74_RS10965 c9ea574ad8177b633f89327bf1670170 327 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 162 7.2E-35 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS10965 c9ea574ad8177b633f89327bf1670170 327 SUPERFAMILY SSF48179 164 284 1.36E-30 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS10965 c9ea574ad8177b633f89327bf1670170 327 PIRSF PIRSF000103 1 312 8.6E-71 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_RS10965 c9ea574ad8177b633f89327bf1670170 327 Gene3D G3DSA:1.10.1040.10 165 285 4.3E-34 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS07360 365d0f305c2a0a5145c3a19c0c9dea91 496 SUPERFAMILY SSF55486 56 225 1.78E-14 T 09-03-2017 UA74_RS07360 365d0f305c2a0a5145c3a19c0c9dea91 496 Pfam PF04228 Putative neutral zinc metallopeptidase 50 218 6.8E-7 T 09-03-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 Pfam PF01029 NusB family 32 154 1.9E-26 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 SUPERFAMILY SSF48013 32 186 4.84E-33 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 355 366 - T 09-03-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 292 302 8.4E-18 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 259 273 8.4E-18 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 406 422 8.4E-18 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 457 474 8.4E-18 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 356 368 8.4E-18 T 09-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 SUPERFAMILY SSF53335 176 474 1.4E-50 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 Gene3D G3DSA:1.10.940.10 30 187 1.9E-46 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 Gene3D G3DSA:3.40.50.150 270 475 3.0E-41 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12360 346be5e857d01d43dc2f81fc1c0a5444 480 Pfam PF01189 16S rRNA methyltransferase RsmB/F 290 472 2.6E-45 T 09-03-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS03990 77ebfdf851f155f1bfbb78b4c8524c2d 99 Gene3D G3DSA:1.10.287.1060 5 96 5.9E-4 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 4.5E-43 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 4.5E-43 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 4.5E-43 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 4.5E-43 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 4.5E-43 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 4.5E-43 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 SUPERFAMILY SSF51905 268 377 1.3E-59 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 SUPERFAMILY SSF51905 7 180 1.3E-59 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 Pfam PF01494 FAD binding domain 8 346 5.0E-69 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 Gene3D G3DSA:3.50.50.60 279 319 4.7E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 Gene3D G3DSA:3.50.50.60 5 171 4.7E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 Gene3D G3DSA:3.30.9.10 172 274 1.9E-10 T 09-03-2017 UA74_RS22905 9b651d99699dbe8a253af938f85e2848 510 Gene3D G3DSA:3.30.9.10 329 356 1.9E-10 T 09-03-2017 UA74_RS03895 dac1c18c016821d40f8def9d890faf48 439 SUPERFAMILY SSF53850 36 431 1.02E-51 T 09-03-2017 UA74_RS03895 dac1c18c016821d40f8def9d890faf48 439 Pfam PF13416 Bacterial extracellular solute-binding protein 61 346 3.9E-15 T 09-03-2017 UA74_RS03895 dac1c18c016821d40f8def9d890faf48 439 Gene3D G3DSA:3.40.190.10 44 167 1.9E-13 T 09-03-2017 UA74_RS03895 dac1c18c016821d40f8def9d890faf48 439 Gene3D G3DSA:3.40.190.10 168 359 1.7E-22 T 09-03-2017 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:2.40.30.10 308 407 7.2E-35 T 09-03-2017 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 696 0.0 T 09-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF50447 267 406 5.81E-33 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF52540 8 284 4.71E-109 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.30.230.10 486 601 1.3E-47 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF54980 608 694 1.97E-30 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 80 90 7.5E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.5E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 60 68 7.5E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 96 107 7.5E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 132 141 7.5E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Pfam PF03144 Elongation factor Tu domain 2 326 393 5.0E-13 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF54211 481 604 8.09E-41 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 SMART SM00889 482 603 8.9E-73 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Pfam PF00009 Elongation factor Tu GTP binding domain 11 284 7.2E-69 T 09-03-2017 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Pfam PF00679 Elongation factor G C-terminus 606 691 1.6E-30 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 2.5E-35 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.40.50.300 8 289 4.3E-107 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Pfam PF03764 Elongation factor G, domain IV 481 603 1.1E-47 T 09-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF54980 406 483 3.96E-25 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.30.70.870 408 482 4.0E-38 T 09-03-2017 UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.30.70.240 602 695 3.4E-34 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 SMART SM00838 605 692 8.4E-58 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Pfam PF14492 Elongation Factor G, domain II 406 480 1.4E-34 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS02915 dda7ef301807cd604661af03398c6c5e 699 Hamap MF_00054_B Elongation factor G [fusA]. 8 696 107.908 T 09-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS01035 9b45820c7637a51a6ed2f7636efc0b05 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 8.8E-20 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS01035 9b45820c7637a51a6ed2f7636efc0b05 331 SMART SM00382 33 231 2.0E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01035 9b45820c7637a51a6ed2f7636efc0b05 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 1.4E-15 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS01035 9b45820c7637a51a6ed2f7636efc0b05 331 SUPERFAMILY SSF52540 3 253 8.11E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01035 9b45820c7637a51a6ed2f7636efc0b05 331 Pfam PF00005 ABC transporter 25 182 1.3E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS01035 9b45820c7637a51a6ed2f7636efc0b05 331 Gene3D G3DSA:3.40.50.300 2 256 4.1E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10465 25565d298c679db9853223c710ba42c1 296 Pfam PF00535 Glycosyl transferase family 2 5 109 5.0E-18 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS10465 25565d298c679db9853223c710ba42c1 296 SUPERFAMILY SSF53448 3 231 1.22E-38 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS10465 25565d298c679db9853223c710ba42c1 296 Gene3D G3DSA:3.90.550.10 3 229 2.5E-29 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Gene3D G3DSA:3.50.50.60 126 336 4.6E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 116 125 8.9E-14 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 182 8.9E-14 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 8.9E-14 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 8.9E-14 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 8.9E-14 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Gene3D G3DSA:3.50.50.60 2 125 4.6E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PIRSF PIRSF037495 1 470 2.5E-120 T 09-03-2017 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Pfam PF04324 BFD-like [2Fe-2S] binding domain 381 432 7.0E-8 T 09-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 SUPERFAMILY SSF51905 1 338 1.21E-39 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.4E-23 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 283 2.4E-23 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 2.4E-23 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 2.4E-23 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 2.4E-23 T 09-03-2017 UA74_RS17040 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 328 4.6E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 Pfam PF00137 ATP synthase subunit C 18 77 3.0E-12 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 SUPERFAMILY SSF81333 17 78 6.67E-17 T 09-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 PRINTS PR00124 ATP synthase C subunit signature 16 35 1.2E-14 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 PRINTS PR00124 ATP synthase C subunit signature 37 52 1.2E-14 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 PRINTS PR00124 ATP synthase C subunit signature 54 79 1.2E-14 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 24 78 4.2E-19 T 09-03-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 Hamap MF_01396 ATP synthase subunit c [atpH]. 13 81 14.047 T 09-03-2017 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 Gene3D G3DSA:1.20.20.10 17 78 4.7E-22 T 09-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 UA74_RS07150 c98654db5df342014569cf4523b66a43 82 ProSitePatterns PS00605 ATP synthase c subunit signature. 44 65 - T 09-03-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 SUPERFAMILY SSF56645 34 297 2.23E-42 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 Gene3D G3DSA:1.20.140.10 275 470 5.8E-40 T 09-03-2017 UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 458 9.9E-14 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 SUPERFAMILY SSF47203 295 481 6.44E-31 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 30 7.1E-8 T 09-03-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 Gene3D G3DSA:1.10.540.10 36 148 4.8E-8 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 Gene3D G3DSA:2.40.110.10 161 274 2.7E-25 T 09-03-2017 UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 610 1.8E-30 T 09-03-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain UA74_RS29980 edb72aca39265f777ab7582948d7acf7 614 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 275 2.1E-17 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS27995 8c536dcb2aece5651bea3ca7919c8c51 455 Pfam PF04024 PspC domain 39 93 3.5E-14 T 09-03-2017 IPR007168 Phage shock protein, PspC, N-terminal UA74_RS27995 8c536dcb2aece5651bea3ca7919c8c51 455 SUPERFAMILY SSF55874 331 450 1.26E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS27995 8c536dcb2aece5651bea3ca7919c8c51 455 Gene3D G3DSA:3.30.565.10 332 452 6.7E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS27995 8c536dcb2aece5651bea3ca7919c8c51 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 451 2.1E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 Pfam PF05175 Methyltransferase small domain 113 198 2.0E-12 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 Gene3D G3DSA:1.10.8.10 7 78 5.7E-16 T 09-03-2017 UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 191 197 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 282 1.1E-64 T 09-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 Gene3D G3DSA:3.40.50.150 89 286 6.3E-55 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 SUPERFAMILY SSF53335 15 283 5.72E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 286 38.158 T 09-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 UA74_RS07115 7a10a4c85e2f0308dfc23951d4ef9f97 290 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 18 286 7.1E-41 T 09-03-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 UA74_RS28310 e674d47adbe33d12a3cc77d15bd51eb3 154 Gene3D G3DSA:2.30.110.10 15 147 7.0E-28 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS28310 e674d47adbe33d12a3cc77d15bd51eb3 154 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 3.0E-37 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS28310 e674d47adbe33d12a3cc77d15bd51eb3 154 SUPERFAMILY SSF50475 15 140 3.37E-29 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS28310 e674d47adbe33d12a3cc77d15bd51eb3 154 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 96 3.3E-13 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS27840 7519d01af595bd0c3584baafc5e21847 219 Gene3D G3DSA:3.40.50.170 21 213 2.6E-67 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS27840 7519d01af595bd0c3584baafc5e21847 219 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 153 176 - T 09-03-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS27840 7519d01af595bd0c3584baafc5e21847 219 SUPERFAMILY SSF53328 22 217 3.92E-58 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS27840 7519d01af595bd0c3584baafc5e21847 219 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 22 208 4.3E-66 T 09-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 UA74_RS27840 7519d01af595bd0c3584baafc5e21847 219 Pfam PF00551 Formyl transferase 22 201 4.3E-51 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS27840 7519d01af595bd0c3584baafc5e21847 219 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 22 207 28.892 T 09-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 UA74_RS01570 c3ccf8559c34c22615c7f311695a67b2 178 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 4.0E-34 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_RS01570 c3ccf8559c34c22615c7f311695a67b2 178 SUPERFAMILY SSF50692 1 115 2.24E-48 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain UA74_RS01570 c3ccf8559c34c22615c7f311695a67b2 178 Pfam PF02261 Aspartate decarboxylase 1 114 2.4E-51 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_RS01570 c3ccf8559c34c22615c7f311695a67b2 178 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 117 1.5E-50 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_RS01570 c3ccf8559c34c22615c7f311695a67b2 178 Gene3D G3DSA:2.40.40.20 1 117 8.5E-55 T 09-03-2017 UA74_RS01570 c3ccf8559c34c22615c7f311695a67b2 178 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 72.724 T 09-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_RS13660 8c72a993dca61c602b74a59e76df02b0 153 SUPERFAMILY SSF54637 5 147 1.12E-32 T 09-03-2017 IPR029069 HotDog domain UA74_RS13660 8c72a993dca61c602b74a59e76df02b0 153 Gene3D G3DSA:3.10.129.10 7 149 2.9E-31 T 09-03-2017 IPR029069 HotDog domain UA74_RS13660 8c72a993dca61c602b74a59e76df02b0 153 Pfam PF01575 MaoC like domain 22 113 2.2E-17 T 09-03-2017 IPR002539 MaoC-like domain UA74_RS23575 260b97468e35a3b87ada788c21728cc9 209 SUPERFAMILY SSF55961 4 141 3.6E-14 T 09-03-2017 UA74_RS23575 260b97468e35a3b87ada788c21728cc9 209 Gene3D G3DSA:3.30.530.20 4 141 9.1E-7 T 09-03-2017 IPR023393 START-like domain UA74_RS23575 260b97468e35a3b87ada788c21728cc9 209 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 141 7.6E-9 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS08975 68690655e7001bbcafc13ecb76b73b02 329 SUPERFAMILY SSF161098 99 309 2.45E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08975 68690655e7001bbcafc13ecb76b73b02 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 326 5.9E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08975 68690655e7001bbcafc13ecb76b73b02 329 Gene3D G3DSA:1.10.3720.10 99 323 1.8E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 4.1E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 4.1E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 4.1E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 Pfam PF00561 alpha/beta hydrolase fold 23 137 3.4E-28 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 SUPERFAMILY SSF53474 4 273 8.45E-72 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 Gene3D G3DSA:3.40.50.1820 2 276 1.5E-77 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 94 107 2.3E-25 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 249 271 2.3E-25 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 108 121 2.3E-25 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 28 46 2.3E-25 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS05830 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 48 63 2.3E-25 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 Gene3D G3DSA:3.40.50.300 338 512 2.6E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 Pfam PF12848 ABC transporter 227 303 7.1E-14 T 09-03-2017 IPR032781 ABC-transporter extension domain UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 Gene3D G3DSA:3.40.50.300 7 284 2.1E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 1.1E-264 T 09-03-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 SUPERFAMILY SSF52540 8 241 3.29E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 Pfam PF00005 ABC transporter 21 188 9.5E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 Pfam PF00005 ABC transporter 338 471 5.2E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 SUPERFAMILY SSF52540 307 507 1.64E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 SMART SM00382 346 516 1.2E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 SMART SM00382 30 240 6.2E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07960 812da9e5addc815d2ec8c1fb4a875b09 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 Gene3D G3DSA:1.10.260.40 4 46 2.1E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 SUPERFAMILY SSF53822 58 347 8.44E-65 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 Gene3D G3DSA:3.40.50.2300 186 321 5.7E-49 T 09-03-2017 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 09-03-2017 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 SUPERFAMILY SSF47413 3 47 2.03E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 Gene3D G3DSA:3.40.50.2300 54 185 1.7E-33 T 09-03-2017 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 46 4.5E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 SMART SM00354 1 68 6.1E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS01765 e68dc23cf3d0f20d601e5a28002f63ff 349 Pfam PF13377 Periplasmic binding protein-like domain 181 344 1.0E-37 T 09-03-2017 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 Pfam PF00230 Major intrinsic protein 6 240 1.2E-37 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 Gene3D G3DSA:1.20.1080.10 4 241 2.9E-76 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 ProSitePatterns PS00221 MIP family signature. 64 72 - T 09-03-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 46 70 8.0E-34 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 5 24 8.0E-34 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 138 156 8.0E-34 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 176 198 8.0E-34 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 223 243 8.0E-34 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 83 102 8.0E-34 T 09-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 UA74_RS27180 33e42cd49f46c72b762f526c85d844de 245 SUPERFAMILY SSF81338 6 242 5.49E-59 T 09-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 SUPERFAMILY SSF49785 438 613 3.83E-28 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 Gene3D G3DSA:2.60.120.260 387 484 9.3E-36 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 Gene3D G3DSA:2.60.120.260 531 612 9.3E-36 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 62 238 1.5E-22 T 09-03-2017 IPR005674 CocE/Serine esterase GO:0016787 UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 SUPERFAMILY SSF53474 31 384 1.68E-67 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 SMART SM00939 350 608 9.4E-37 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 64 335 7.5E-50 T 09-03-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 Gene3D G3DSA:3.40.50.1820 282 386 4.0E-84 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 Gene3D G3DSA:3.40.50.1820 49 222 4.0E-84 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27095 abd40dd1c524ce00743460fd13f527de 648 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 362 602 7.8E-30 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 SMART SM00347 26 126 4.4E-23 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 Pfam PF01047 MarR family 34 90 1.5E-17 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 Gene3D G3DSA:1.10.10.10 5 138 4.1E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.6E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.6E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.6E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS28490 555e7e3482a19528b665346f91be6fd0 142 SUPERFAMILY SSF46785 8 138 3.03E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 225 246 - T 09-03-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 33 427 3.3E-175 T 09-03-2017 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 SUPERFAMILY SSF51735 195 386 3.97E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 SMART SM00829 51 415 1.3E-11 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 112 190 6.6E-7 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 SUPERFAMILY SSF50129 47 230 6.63E-30 T 09-03-2017 IPR011032 GroES-like UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 Pfam PF00107 Zinc-binding dehydrogenase 236 379 3.4E-34 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 Gene3D G3DSA:3.40.50.720 232 364 1.4E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17335 3914f8b571098ecec698f4cf81aacdaa 449 Gene3D G3DSA:3.90.180.10 43 231 7.8E-32 T 09-03-2017 IPR011032 GroES-like UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 79 89 - T 09-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Gene3D G3DSA:2.10.240.10 245 281 1.8E-10 T 09-03-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 SUPERFAMILY SSF52343 120 281 1.44E-18 T 09-03-2017 UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Gene3D G3DSA:3.40.50.80 129 243 8.4E-9 T 09-03-2017 UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 SUPERFAMILY SSF63380 28 125 4.12E-15 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Gene3D G3DSA:2.40.30.10 29 123 1.9E-19 T 09-03-2017 UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 245 281 2.0E-9 T 09-03-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UA74_RS24120 b9cf769364eaf7dd0a6a2fb6f4be915c 287 PIRSF PIRSF006816 27 287 2.6E-43 T 09-03-2017 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 PIRSF PIRSF005719 1 1188 5.7E-249 T 09-03-2017 IPR024704 Structural maintenance of chromosomes protein UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1188 8.7E-280 T 09-03-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 624 2.7E-17 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1187 21.935 T 09-03-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1181 2.5E-71 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 SUPERFAMILY SSF52540 2 207 1.87E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 SUPERFAMILY SSF52540 997 1182 1.87E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 SUPERFAMILY SSF75553 465 669 1.83E-25 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 SMART SM00968 512 625 9.4E-17 T 09-03-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 Gene3D G3DSA:3.40.50.300 1037 1183 8.6E-88 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25705 b6c864b18486619ec8948cf4ecd16c17 1188 Gene3D G3DSA:3.40.50.300 2 163 8.6E-88 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19665 1dcce80afcdd66b56a48d91d2625d7ff 158 Pfam PF03995 Peptidase inhibitor family I36 55 128 1.6E-7 T 09-03-2017 UA74_RS13695 bf569dafcda8d3ccc9d75364b6219b9f 425 SUPERFAMILY SSF53756 113 392 7.99E-67 T 09-03-2017 UA74_RS13695 bf569dafcda8d3ccc9d75364b6219b9f 425 SUPERFAMILY SSF53756 3 51 7.99E-67 T 09-03-2017 UA74_RS13695 bf569dafcda8d3ccc9d75364b6219b9f 425 Gene3D G3DSA:3.40.50.2000 7 238 8.1E-14 T 09-03-2017 UA74_RS13695 bf569dafcda8d3ccc9d75364b6219b9f 425 Gene3D G3DSA:3.40.50.2000 239 382 1.2E-29 T 09-03-2017 UA74_RS13695 bf569dafcda8d3ccc9d75364b6219b9f 425 Pfam PF06722 Protein of unknown function (DUF1205) 195 287 1.8E-15 T 09-03-2017 IPR010610 Domain of unknown function DUF1205 UA74_RS07830 65da55deccaa081d413a1608ecf5d469 340 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 330 3.2E-119 T 09-03-2017 IPR019949 Luciferase family oxidoreductase, group 1 UA74_RS07830 65da55deccaa081d413a1608ecf5d469 340 Pfam PF00296 Luciferase-like monooxygenase 14 306 2.6E-39 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS07830 65da55deccaa081d413a1608ecf5d469 340 Gene3D G3DSA:3.20.20.30 7 329 4.3E-87 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS07830 65da55deccaa081d413a1608ecf5d469 340 SUPERFAMILY SSF51679 7 329 5.23E-75 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 SUPERFAMILY SSF55973 123 247 5.49E-44 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 SUPERFAMILY SSF55973 6 112 6.47E-45 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 Gene3D G3DSA:3.30.300.10 149 248 7.8E-39 T 09-03-2017 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 248 387 1.8E-65 T 09-03-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 Gene3D G3DSA:3.30.300.10 14 148 1.5E-46 T 09-03-2017 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 104 1.6E-40 T 09-03-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 5 398 55.338 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 PIRSF PIRSF000497 1 398 9.8E-163 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 127 246 5.2E-43 T 09-03-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 09-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 8 396 1.3E-164 T 09-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 274 282 - T 09-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 Gene3D G3DSA:3.30.300.10 259 398 3.6E-66 T 09-03-2017 UA74_RS12330 ac48c16bbb1fcc11c50422be03d5d9f9 400 SUPERFAMILY SSF55973 248 397 7.85E-66 T 09-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_RS27040 af87f852430a1d442cefac6edc1bc134 105 Gene3D G3DSA:1.10.287.1060 2 95 6.1E-7 T 09-03-2017 UA74_RS27040 af87f852430a1d442cefac6edc1bc134 105 SUPERFAMILY SSF140453 1 98 6.02E-12 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS27040 af87f852430a1d442cefac6edc1bc134 105 Pfam PF06013 Proteins of 100 residues with WXG 2 91 1.9E-6 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Pfam PF13377 Periplasmic binding protein-like domain 184 343 2.0E-36 T 09-03-2017 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 SUPERFAMILY SSF47413 18 77 1.94E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 65 2.2E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 SUPERFAMILY SSF53822 79 346 1.02E-66 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Gene3D G3DSA:1.10.260.40 19 71 3.9E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Gene3D G3DSA:3.40.50.2300 189 344 2.2E-51 T 09-03-2017 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 30 40 9.6E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 20 30 9.6E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 SMART SM00354 18 89 3.7E-21 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 21 39 - T 09-03-2017 UA74_RS24215 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Gene3D G3DSA:3.40.50.2300 72 188 1.3E-32 T 09-03-2017 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 SUPERFAMILY SSF51445 41 488 1.56E-131 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 SMART SM00642 38 440 3.2E-114 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:2.60.40.1180 488 573 4.2E-13 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:3.20.20.80 32 129 6.3E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:3.20.20.80 205 434 6.3E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:3.20.20.80 467 480 6.3E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 SUPERFAMILY SSF51011 492 573 3.15E-15 T 09-03-2017 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 Pfam PF00128 Alpha amylase, catalytic domain 53 409 1.2E-76 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:3.90.400.10 130 197 2.2E-24 T 09-03-2017 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 30 573 8.4E-288 T 09-03-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 UA74_RS07620 9a7db41a6b3148cb2d3b8276188fa8a8 580 Pfam PF16657 Maltogenic Amylase, C-terminal domain 488 570 9.6E-22 T 09-03-2017 IPR032091 Maltogenic Amylase, C-terminal UA74_RS08040 f56d80c03c4b4335d1c93e35fb3d527c 164 Pfam PF17174 Domain of unknown function (DUF5130) 18 154 4.3E-33 T 09-03-2017 IPR033437 Protein of unknown function DUF5130 UA74_RS03795 791c5bab6a562efb318296744895350d 333 SUPERFAMILY SSF52540 30 296 1.61E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03795 791c5bab6a562efb318296744895350d 333 Gene3D G3DSA:3.40.50.300 34 196 2.8E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03795 791c5bab6a562efb318296744895350d 333 SMART SM00382 47 188 0.0015 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS03795 791c5bab6a562efb318296744895350d 333 Gene3D G3DSA:1.10.8.300 212 320 1.7E-32 T 09-03-2017 UA74_RS03795 791c5bab6a562efb318296744895350d 333 PIRSF PIRSF002849 4 325 3.2E-124 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted UA74_RS03795 791c5bab6a562efb318296744895350d 333 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 50 180 1.2E-62 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Hamap MF_00974 DNA primase [dnaG]. 4 621 25.794 T 09-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 TIGRFAM TIGR01391 dnaG: DNA primase 5 427 2.9E-109 T 09-03-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 1.1E-34 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 SMART SM00493 262 344 4.6E-10 T 09-03-2017 IPR006171 Toprim domain UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 SUPERFAMILY SSF57783 4 100 5.61E-32 T 09-03-2017 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Gene3D G3DSA:1.20.50.20 379 434 4.9E-12 T 09-03-2017 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF10410 DnaB-helicase binding domain of primase 381 434 1.6E-16 T 09-03-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 PIRSF PIRSF002811 2 627 1.9E-140 T 09-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF01807 CHC2 zinc finger 7 100 1.5E-32 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Gene3D G3DSA:3.90.980.10 117 242 7.2E-36 T 09-03-2017 IPR013264 DNA primase, catalytic core, N-terminal UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Gene3D G3DSA:3.90.580.10 3 100 5.6E-36 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 SMART SM00400 37 91 5.7E-34 T 09-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF08278 DNA primase DnaG DnaB-binding 488 615 2.6E-22 T 09-03-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Gene3D G3DSA:3.40.1360.10 244 377 1.7E-39 T 09-03-2017 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF13662 Toprim domain 263 337 8.7E-17 T 09-03-2017 IPR006171 Toprim domain UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 SUPERFAMILY SSF56731 117 434 4.18E-89 T 09-03-2017 UA74_RS24460 b6fd22fe15066a2fe807d1c604e28272 638 SMART SM00766 487 616 6.5E-18 T 09-03-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 Gene3D G3DSA:1.10.630.10 20 411 1.3E-119 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 Pfam PF00067 Cytochrome P450 216 381 2.9E-30 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 SUPERFAMILY SSF48264 21 411 1.96E-94 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 165 180 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 283 294 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 360 371 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 101 112 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 202 224 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 329 344 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 351 360 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 301 328 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00359 B-class P450 signature 148 164 1.6E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00385 P450 superfamily signature 248 265 1.1E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00385 P450 superfamily signature 283 294 1.1E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00385 P450 superfamily signature 351 360 1.1E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17500 a48bf87edc2d0a4c9d4c6e3e6d9703b8 411 PRINTS PR00385 P450 superfamily signature 360 371 1.1E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06285 7317b2ed96434b4a2e823c83cf3beb80 435 SUPERFAMILY SSF51690 141 430 1.46E-83 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UA74_RS06285 7317b2ed96434b4a2e823c83cf3beb80 435 PIRSF PIRSF000484 6 431 1.2E-94 T 09-03-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 UA74_RS06285 7317b2ed96434b4a2e823c83cf3beb80 435 Gene3D G3DSA:3.20.140.10 10 369 1.1E-87 T 09-03-2017 UA74_RS06285 7317b2ed96434b4a2e823c83cf3beb80 435 SUPERFAMILY SSF54675 9 138 1.1E-38 T 09-03-2017 UA74_RS06285 7317b2ed96434b4a2e823c83cf3beb80 435 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 12 419 5.0E-126 T 09-03-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 UA74_RS06285 7317b2ed96434b4a2e823c83cf3beb80 435 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 141 310 3.0E-6 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UA74_RS08580 4a5650e47333bb10dda5e0d2326611c8 221 SUPERFAMILY SSF51735 2 140 7.48E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08580 4a5650e47333bb10dda5e0d2326611c8 221 SUPERFAMILY SSF116726 130 208 2.49E-6 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS08580 4a5650e47333bb10dda5e0d2326611c8 221 Pfam PF02254 TrkA-N domain 3 117 1.3E-22 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_RS08580 4a5650e47333bb10dda5e0d2326611c8 221 Gene3D G3DSA:3.30.70.1450 149 201 3.2E-4 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS08580 4a5650e47333bb10dda5e0d2326611c8 221 Pfam PF02080 TrkA-C domain 147 208 8.5E-8 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS08580 4a5650e47333bb10dda5e0d2326611c8 221 Gene3D G3DSA:3.40.50.720 2 140 1.5E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20080 e78db31f4cdbc81dbd62713a52ec346e 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 5 151 6.6E-63 T 09-03-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 UA74_RS20080 e78db31f4cdbc81dbd62713a52ec346e 162 Gene3D G3DSA:3.40.1400.10 5 153 8.0E-49 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS20080 e78db31f4cdbc81dbd62713a52ec346e 162 Pfam PF02502 Ribose/Galactose Isomerase 7 145 9.6E-44 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS20080 e78db31f4cdbc81dbd62713a52ec346e 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 7 151 1.2E-31 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS20080 e78db31f4cdbc81dbd62713a52ec346e 162 PIRSF PIRSF005384 5 153 1.1E-43 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS20080 e78db31f4cdbc81dbd62713a52ec346e 162 SUPERFAMILY SSF89623 4 151 2.22E-46 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 SUPERFAMILY SSF56059 689 964 4.42E-93 T 09-03-2017 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:1.10.1030.10 399 538 2.8E-41 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 689 888 1.5E-32 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.2E-66 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 SUPERFAMILY SSF48108 396 553 5.36E-40 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1071 12.429 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:3.30.1490.20 702 761 9.1E-27 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:3.30.1490.20 142 199 2.9E-20 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 725 739 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:3.40.50.1380 963 1020 1.3E-4 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 SMART SM01096 426 549 4.1E-56 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 854 861 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:3.30.470.20 762 962 1.3E-64 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:3.30.470.20 200 398 7.8E-75 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:3.40.50.20 4 108 6.7E-43 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 SUPERFAMILY SSF56059 128 400 1.61E-101 T 09-03-2017 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 SUPERFAMILY SSF52440 1 127 5.04E-47 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1069 0.0 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Gene3D G3DSA:3.40.50.20 539 678 8.1E-53 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 9.6E-36 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 SUPERFAMILY SSF52440 563 690 7.77E-42 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.8E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.8E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.8E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 3.8E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS17195 686a10f0b1a782cf48526d7f8f246b31 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.8E-62 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 PIRSF PIRSF001589 1 634 2.5E-172 T 09-03-2017 UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 SUPERFAMILY SSF52402 479 617 4.19E-82 T 09-03-2017 UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 SUPERFAMILY SSF52402 249 392 4.19E-82 T 09-03-2017 UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 Gene3D G3DSA:3.40.50.620 232 388 7.1E-94 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 Gene3D G3DSA:3.40.50.620 474 621 7.1E-94 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 Gene3D G3DSA:3.60.20.10 2 231 4.5E-65 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 Pfam PF00733 Asparagine synthase 253 621 8.4E-101 T 09-03-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 SUPERFAMILY SSF56235 2 232 3.69E-53 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 559 2.9E-142 T 09-03-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UA74_RS25085 ae6573e964fc4f84ed2f495141882f9d 642 Pfam PF13537 Glutamine amidotransferase domain 50 172 6.5E-38 T 09-03-2017 IPR017932 Glutamine amidotransferase type 2 domain UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 21 426 7.9E-107 T 09-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 SUPERFAMILY SSF82866 230 432 1.44E-33 T 09-03-2017 UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 PRINTS PR01755 Bacterial translocase SecF protein signature 486 501 1.3E-22 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 PRINTS PR01755 Bacterial translocase SecF protein signature 643 661 1.3E-22 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 PRINTS PR01755 Bacterial translocase SecF protein signature 675 690 1.3E-22 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 PRINTS PR01755 Bacterial translocase SecF protein signature 595 609 1.3E-22 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Pfam PF07549 SecD/SecF GG Motif 483 506 3.0E-8 T 09-03-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Pfam PF07549 SecD/SecF GG Motif 13 34 7.4E-4 T 09-03-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 439 32.859 T 09-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 194 420 2.0E-58 T 09-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 487 727 2.9E-53 T 09-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 461 738 22.728 T 09-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 SUPERFAMILY SSF82866 567 733 4.58E-26 T 09-03-2017 UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Pfam PF02355 Protein export membrane protein 558 734 6.2E-49 T 09-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Pfam PF02355 Protein export membrane protein 254 423 3.1E-9 T 09-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Gene3D G3DSA:1.20.1640.10 572 738 1.4E-19 T 09-03-2017 UA74_RS12765 2cbe23524743bf68b4fe0a786abe0bc0 759 Gene3D G3DSA:1.20.1640.10 230 436 1.2E-23 T 09-03-2017 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 427 1.4E-104 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 Gene3D G3DSA:3.40.50.720 241 450 2.7E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 SUPERFAMILY SSF51735 11 196 2.35E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 SUPERFAMILY SSF52413 318 437 1.14E-25 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 PIRSF PIRSF000124 10 450 2.6E-106 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 330 427 2.3E-21 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 SMART SM00984 330 432 2.3E-26 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 SUPERFAMILY SSF48179 209 305 9.18E-23 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 188 4.4E-44 T 09-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 PIRSF PIRSF500136 5 445 7.2E-114 T 09-03-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 303 2.0E-20 T 09-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS17520 15b8cb1f385a94086b3b5b8826c5b7c6 450 Gene3D G3DSA:3.40.50.720 10 230 3.0E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02365 578866789321f0db907ce5f741f7b411 196 ProSitePatterns PS00194 Thioredoxin family active site. 82 100 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_RS02365 578866789321f0db907ce5f741f7b411 196 Pfam PF00578 AhpC/TSA family 55 173 9.1E-15 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS02365 578866789321f0db907ce5f741f7b411 196 Gene3D G3DSA:3.40.30.10 1 195 1.8E-31 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS02365 578866789321f0db907ce5f741f7b411 196 SUPERFAMILY SSF52833 54 195 2.13E-24 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 ProSitePatterns PS00802 Transketolase signature 2. 423 439 - T 09-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 SMART SM00861 317 482 8.5E-52 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 SUPERFAMILY SSF52922 518 642 1.31E-24 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 SUPERFAMILY SSF52518 296 478 4.98E-51 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Gene3D G3DSA:3.40.50.970 18 192 1.1E-56 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Gene3D G3DSA:3.40.50.970 240 331 1.1E-56 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 481 2.3E-157 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Pfam PF02779 Transketolase, pyrimidine binding domain 318 478 1.8E-37 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Pfam PF02780 Transketolase, C-terminal domain 517 635 2.4E-24 T 09-03-2017 IPR033248 Transketolase, C-terminal domain UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Gene3D G3DSA:3.40.50.920 517 642 1.1E-27 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 SUPERFAMILY SSF52518 3 348 2.75E-67 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 280 3.0E-106 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 644 40.809 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS08595 06adcc0f0960e5175c82b782fe1786f0 662 Gene3D G3DSA:3.40.50.970 332 478 2.9E-27 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 Pfam PF00082 Subtilase family 176 446 2.1E-37 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 Pfam PF13620 Carboxypeptidase regulatory-like domain 567 642 4.8E-9 T 09-03-2017 UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 Pfam PF13620 Carboxypeptidase regulatory-like domain 484 560 1.1E-10 T 09-03-2017 UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 Gene3D G3DSA:3.40.50.200 156 473 7.5E-68 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 SUPERFAMILY SSF49452 478 559 3.33E-11 T 09-03-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 Gene3D G3DSA:2.60.40.1120 484 559 1.4E-15 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 SUPERFAMILY SSF49452 561 642 3.14E-9 T 09-03-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 SUPERFAMILY SSF52743 153 476 3.27E-59 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 Gene3D G3DSA:2.60.40.1120 567 650 4.4E-8 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 407 417 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 234 244 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 243 2.2E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 PRINTS PR00723 Subtilisin serine protease family (S8) signature 176 195 2.2E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11310 ad59291b6802b5f5e686673bbfdd1b17 840 PRINTS PR00723 Subtilisin serine protease family (S8) signature 406 422 2.2E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 SUPERFAMILY SSF50494 5 229 4.37E-43 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 SMART SM00020 29 224 2.2E-30 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 Gene3D G3DSA:2.40.10.10 30 62 4.3E-11 T 09-03-2017 UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 Gene3D G3DSA:2.40.10.10 63 228 1.2E-29 T 09-03-2017 UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 99 113 5.6E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 55 70 5.6E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 175 187 5.6E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS19770 1c553cb35d89ca5cb6603c9d17f57455 230 Pfam PF00089 Trypsin 30 224 1.4E-28 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 Gene3D G3DSA:2.40.50.140 44 137 2.3E-20 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 Pfam PF00271 Helicase conserved C-terminal domain 547 621 3.8E-19 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 Pfam PF00270 DEAD/DEAH box helicase 292 446 4.2E-17 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 Gene3D G3DSA:3.40.50.300 473 670 8.8E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 24 698 1.9E-201 T 09-03-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 SMART SM00490 537 622 5.1E-22 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 SUPERFAMILY SSF52540 400 507 1.5E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 SUPERFAMILY SSF52540 542 632 1.5E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 SMART SM00487 266 470 8.4E-29 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 Gene3D G3DSA:3.40.50.300 256 466 2.3E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 SUPERFAMILY SSF50249 12 181 1.03E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 Pfam PF17191 RecG wedge domain 13 176 4.0E-11 T 09-03-2017 IPR033454 RecG, wedge domain UA74_RS25885 52508209586783d71c2059fbb2ae4d31 734 SUPERFAMILY SSF52540 187 463 2.38E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 2.3E-28 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 163 178 2.3E-28 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 2.3E-28 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 184 206 2.3E-28 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 SUPERFAMILY SSF55174 328 421 1.35E-15 T 09-03-2017 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 Gene3D G3DSA:3.10.290.10 319 422 4.2E-28 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 422 42.328 T 09-03-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 Gene3D G3DSA:1.10.240.10 234 318 1.0E-36 T 09-03-2017 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 Gene3D G3DSA:3.40.50.620 3 233 2.3E-86 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 Pfam PF00579 tRNA synthetases class I (W and Y) 31 325 5.5E-79 T 09-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 SUPERFAMILY SSF52374 4 325 1.31E-91 T 09-03-2017 UA74_RS21650 30cda7b4372008390fdfcf21c17956b2 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 420 2.6E-102 T 09-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_RS12200 ee4f809776fd7f99af2dd561b51d0dda 152 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 67 79 - T 09-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UA74_RS12200 ee4f809776fd7f99af2dd561b51d0dda 152 SUPERFAMILY SSF51261 3 148 2.96E-37 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS12200 ee4f809776fd7f99af2dd561b51d0dda 152 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 4 125 2.3E-40 T 09-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UA74_RS12200 ee4f809776fd7f99af2dd561b51d0dda 152 Gene3D G3DSA:2.70.70.10 3 149 1.1E-45 T 09-03-2017 UA74_RS12200 ee4f809776fd7f99af2dd561b51d0dda 152 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 5 122 7.7E-32 T 09-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UA74_RS27130 a8556c1a593c8ac626b6fb5c048ae2c0 209 SUPERFAMILY SSF52972 2 198 4.71E-44 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_RS27130 a8556c1a593c8ac626b6fb5c048ae2c0 209 Gene3D G3DSA:3.90.950.10 2 203 3.6E-56 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_RS27130 a8556c1a593c8ac626b6fb5c048ae2c0 209 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 197 6.8E-44 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 UA74_RS27130 a8556c1a593c8ac626b6fb5c048ae2c0 209 PIRSF PIRSF006305 1 206 3.2E-38 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 UA74_RS27130 a8556c1a593c8ac626b6fb5c048ae2c0 209 Pfam PF02545 Maf-like protein 2 199 1.5E-43 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 UA74_RS27130 a8556c1a593c8ac626b6fb5c048ae2c0 209 Hamap MF_00528 Septum formation protein Maf [maf]. 2 204 24.665 T 09-03-2017 IPR003697 Maf-like protein GO:0005737 UA74_RS17480 6c92bf397a788be8fb29fb696aa45a5c 319 Gene3D G3DSA:1.10.10.10 3 54 1.8E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17480 6c92bf397a788be8fb29fb696aa45a5c 319 Gene3D G3DSA:1.10.10.10 261 318 1.7E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17480 6c92bf397a788be8fb29fb696aa45a5c 319 SUPERFAMILY SSF46785 2 57 4.38E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17480 6c92bf397a788be8fb29fb696aa45a5c 319 Pfam PF00196 Bacterial regulatory proteins, luxR family 261 309 4.6E-7 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17480 6c92bf397a788be8fb29fb696aa45a5c 319 SUPERFAMILY SSF46894 261 319 1.67E-10 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS17480 6c92bf397a788be8fb29fb696aa45a5c 319 SMART SM00421 255 313 3.4E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 SUPERFAMILY SSF81624 2 142 7.72E-21 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 Gene3D G3DSA:1.10.8.50 140 272 9.6E-30 T 09-03-2017 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 146 219 3.7E-13 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 Gene3D G3DSA:3.20.190.10 2 139 1.6E-19 T 09-03-2017 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 SMART SM01232 139 226 6.6E-18 T 09-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 85 3.3E-15 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 Pfam PF06827 Zinc finger found in FPG and IleRS 244 271 5.8E-8 T 09-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 SUPERFAMILY SSF46946 139 219 1.83E-16 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 SUPERFAMILY SSF57716 233 271 1.08E-11 T 09-03-2017 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 ProSitePatterns PS01242 Zinc finger FPG-type signature. 247 271 - T 09-03-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 UA74_RS00370 15199fa35fb2d01aab8227ee286ceacb 287 SMART SM00898 2 125 1.2E-21 T 09-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_RS17115 99e6c65c563aee1f767252b7dc832b2c 303 SUPERFAMILY SSF53167 2 246 1.57E-38 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS17115 99e6c65c563aee1f767252b7dc832b2c 303 Pfam PF01048 Phosphorylase superfamily 2 242 8.4E-29 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS17115 99e6c65c563aee1f767252b7dc832b2c 303 Gene3D G3DSA:3.40.50.1580 1 249 1.2E-42 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS26645 b78032879c040b9a5c2268863d73e1b6 158 Pfam PF04073 Aminoacyl-tRNA editing domain 35 147 3.0E-25 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS26645 b78032879c040b9a5c2268863d73e1b6 158 PIRSF PIRSF006181 2 158 3.4E-50 T 09-03-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC UA74_RS26645 b78032879c040b9a5c2268863d73e1b6 158 Gene3D G3DSA:3.90.960.10 6 157 9.6E-55 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS26645 b78032879c040b9a5c2268863d73e1b6 158 SUPERFAMILY SSF55826 6 156 6.15E-41 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS26645 b78032879c040b9a5c2268863d73e1b6 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 6.8E-54 T 09-03-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 SUPERFAMILY SSF50129 9 171 1.19E-52 T 09-03-2017 IPR011032 GroES-like UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 Gene3D G3DSA:3.90.180.10 6 179 3.0E-65 T 09-03-2017 IPR011032 GroES-like UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 SMART SM00829 11 341 1.9E-7 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 Pfam PF00107 Zinc-binding dehydrogenase 185 307 1.6E-20 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 SUPERFAMILY SSF51735 148 311 1.88E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 142 1.6E-28 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS25475 30282c5f7f028670c34d78a504b58a09 348 Gene3D G3DSA:3.40.50.720 180 291 9.8E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 Gene3D G3DSA:2.60.120.260 660 793 3.4E-23 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 Gene3D G3DSA:2.120.10.30 222 521 1.4E-19 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 Pfam PF07691 PA14 domain 30 162 1.1E-15 T 09-03-2017 IPR011658 PA14 domain UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 Gene3D G3DSA:3.90.182.10 75 196 3.1E-22 T 09-03-2017 IPR011658 PA14 domain UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 SUPERFAMILY SSF101898 221 426 1.62E-10 T 09-03-2017 UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 Pfam PF06439 Domain of Unknown Function (DUF1080) 797 986 1.5E-35 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 SUPERFAMILY SSF56988 77 194 7.59E-11 T 09-03-2017 UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 SUPERFAMILY SSF49785 662 793 1.63E-21 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 SMART SM00758 29 169 1.5E-25 T 09-03-2017 IPR011658 PA14 domain UA74_RS05445 4fa5de7f730049e0bf3d167905960e1d 988 Pfam PF16990 Carbohydrate binding module (family 35) 663 793 1.2E-6 T 09-03-2017 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_RS21040 76d8679c76c008d076d91e9ca2a983ec 285 SMART SM00530 17 72 0.0034 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS21040 76d8679c76c008d076d91e9ca2a983ec 285 Gene3D G3DSA:1.10.260.40 5 70 4.4E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS21040 76d8679c76c008d076d91e9ca2a983ec 285 SUPERFAMILY SSF47413 13 70 1.33E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS21040 76d8679c76c008d076d91e9ca2a983ec 285 Pfam PF13560 Helix-turn-helix domain 13 74 1.8E-10 T 09-03-2017 UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 Pfam PF01012 Electron transfer flavoprotein domain 4 172 3.7E-26 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 258 284 - T 09-03-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 Gene3D G3DSA:3.40.50.1220 192 314 9.1E-57 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 195 277 1.6E-34 T 09-03-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 SUPERFAMILY SSF52467 194 313 3.53E-46 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 PIRSF PIRSF000089 1 319 2.4E-95 T 09-03-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 SUPERFAMILY SSF52402 4 177 2.01E-37 T 09-03-2017 UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 Gene3D G3DSA:3.40.50.620 1 176 4.0E-36 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS06535 c69137e759379b71c5cc6099a4dab63d 319 SMART SM00893 4 182 7.7E-24 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_RS02840 1c200a6a3b987f36937a886612a49ef2 186 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 66 140 0.006 T 09-03-2017 UA74_RS02840 1c200a6a3b987f36937a886612a49ef2 186 SUPERFAMILY SSF160369 1 169 1.01E-48 T 09-03-2017 UA74_RS02840 1c200a6a3b987f36937a886612a49ef2 186 Pfam PF00466 Ribosomal protein L10 1 98 6.9E-25 T 09-03-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 UA74_RS02840 1c200a6a3b987f36937a886612a49ef2 186 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.058 T 09-03-2017 IPR022973 Ribosomal protein L10 UA74_RS06490 160d14cae7b9adb38be1470ba65a63cd 515 Gene3D G3DSA:3.20.110.10 11 395 7.9E-118 T 09-03-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain UA74_RS06490 160d14cae7b9adb38be1470ba65a63cd 515 SUPERFAMILY SSF88688 390 507 1.08E-18 T 09-03-2017 IPR028995 Glycoside hydrolase families 57/38, central domain UA74_RS06490 160d14cae7b9adb38be1470ba65a63cd 515 SUPERFAMILY SSF88713 12 395 1.6E-93 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UA74_RS06490 160d14cae7b9adb38be1470ba65a63cd 515 Pfam PF03065 Glycosyl hydrolase family 57 15 345 1.1E-21 T 09-03-2017 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 UA74_RS06490 160d14cae7b9adb38be1470ba65a63cd 515 Pfam PF09210 Domain of unknown function (DUF1957) 411 505 1.4E-19 T 09-03-2017 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 UA74_RS06490 160d14cae7b9adb38be1470ba65a63cd 515 Gene3D G3DSA:1.20.1430.10 415 488 3.7E-14 T 09-03-2017 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 UA74_RS23440 48b90b524cf5796a1947cd01831070c6 189 SUPERFAMILY SSF46689 8 69 1.18E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS23440 48b90b524cf5796a1947cd01831070c6 189 Gene3D G3DSA:1.10.357.10 52 183 1.0E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS23440 48b90b524cf5796a1947cd01831070c6 189 SUPERFAMILY SSF48498 77 183 1.78E-18 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS23440 48b90b524cf5796a1947cd01831070c6 189 Pfam PF13305 WHG domain 84 160 1.8E-8 T 09-03-2017 IPR025996 WHG domain UA74_RS23440 48b90b524cf5796a1947cd01831070c6 189 Gene3D G3DSA:1.10.10.60 2 48 1.7E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS23440 48b90b524cf5796a1947cd01831070c6 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 9.2E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS24600 bba91bf14f70b5f267ad0c636980635a 339 Gene3D G3DSA:3.40.50.300 106 310 4.4E-100 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24600 bba91bf14f70b5f267ad0c636980635a 339 SUPERFAMILY SSF52540 106 274 1.98E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24600 bba91bf14f70b5f267ad0c636980635a 339 Pfam PF02562 PhoH-like protein 107 310 7.7E-94 T 09-03-2017 IPR003714 PhoH-like protein GO:0005524 UA74_RS24100 be9599105dd1a3c7fdf6d27f58803cd3 257 SUPERFAMILY SSF46785 2 67 4.02E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24100 be9599105dd1a3c7fdf6d27f58803cd3 257 Gene3D G3DSA:1.10.10.10 2 65 7.8E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24100 be9599105dd1a3c7fdf6d27f58803cd3 257 Gene3D G3DSA:3.30.450.40 80 246 4.7E-37 T 09-03-2017 IPR029016 GAF domain-like UA74_RS24100 be9599105dd1a3c7fdf6d27f58803cd3 257 SUPERFAMILY SSF55781 71 244 3.79E-35 T 09-03-2017 IPR029016 GAF domain-like UA74_RS24100 be9599105dd1a3c7fdf6d27f58803cd3 257 Pfam PF01614 Bacterial transcriptional regulator 117 239 3.6E-22 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS24100 be9599105dd1a3c7fdf6d27f58803cd3 257 Pfam PF09339 IclR helix-turn-helix domain 2 49 2.6E-10 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS24100 be9599105dd1a3c7fdf6d27f58803cd3 257 SMART SM00346 1 87 4.0E-4 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS17780 c98be6cc67d4cfe82b482140efa6383b 248 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 16 223 19.594 T 09-03-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 UA74_RS17780 c98be6cc67d4cfe82b482140efa6383b 248 Pfam PF02525 Flavodoxin-like fold 16 201 9.7E-22 T 09-03-2017 IPR003680 Flavodoxin-like fold UA74_RS17780 c98be6cc67d4cfe82b482140efa6383b 248 SUPERFAMILY SSF52218 16 200 2.56E-24 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS17780 c98be6cc67d4cfe82b482140efa6383b 248 Gene3D G3DSA:3.40.50.360 16 209 1.7E-33 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SMART SM00086 330 371 6.0 T 09-03-2017 IPR001610 PAC motif UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SMART SM00086 203 244 2.9 T 09-03-2017 IPR001610 PAC motif UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SMART SM00086 77 118 3.2 T 09-03-2017 IPR001610 PAC motif UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Pfam PF08447 PAS fold 153 237 3.3E-12 T 09-03-2017 IPR013655 PAS fold-3 GO:0005515 UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Gene3D G3DSA:3.30.450.20 30 124 1.8E-5 T 09-03-2017 UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Gene3D G3DSA:3.30.450.20 125 241 1.8E-20 T 09-03-2017 UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SUPERFAMILY SSF55785 115 242 2.09E-18 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Pfam PF00563 EAL domain 557 791 4.5E-63 T 09-03-2017 IPR001633 EAL domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Gene3D G3DSA:3.30.450.20 242 369 1.3E-20 T 09-03-2017 UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SMART SM00052 551 796 1.6E-87 T 09-03-2017 IPR001633 EAL domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SMART SM00091 256 322 3.7E-8 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SMART SM00091 127 197 12.0 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Gene3D G3DSA:3.30.70.270 383 544 1.5E-44 T 09-03-2017 UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SUPERFAMILY SSF55785 52 126 1.92E-5 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 378 540 1.3E-32 T 09-03-2017 IPR000160 GGDEF domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Pfam PF00990 Diguanylate cyclase, GGDEF domain 382 536 5.8E-34 T 09-03-2017 IPR000160 GGDEF domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Pfam PF08448 PAS fold 266 373 2.7E-12 T 09-03-2017 IPR013656 PAS fold-4 UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SMART SM00267 371 541 4.1E-51 T 09-03-2017 IPR000160 GGDEF domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 254 378 2.6E-19 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 250 5.9E-7 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Pfam PF13426 PAS domain 55 117 2.1 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 Gene3D G3DSA:3.20.20.450 554 801 7.7E-83 T 09-03-2017 IPR001633 EAL domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SUPERFAMILY SSF55073 387 540 3.14E-38 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SUPERFAMILY SSF55785 242 369 5.48E-20 T 09-03-2017 IPR000014 PAS domain UA74_RS26580 d8465bd3dc8223624eff49a5911bf53d 812 SUPERFAMILY SSF141868 556 801 4.18E-77 T 09-03-2017 IPR001633 EAL domain UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 217 512 1.2E-109 T 09-03-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 Gene3D G3DSA:3.30.360.10 215 512 3.2E-117 T 09-03-2017 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 247 264 6.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 354 380 6.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 195 223 6.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 184 6.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 265 281 6.3E-49 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 SUPERFAMILY SSF51735 16 218 2.56E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 26 513 86.655 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 PIRSF PIRSF000110 5 514 6.0E-174 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 SUPERFAMILY SSF55347 205 512 2.81E-110 T 09-03-2017 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 30 215 1.5E-60 T 09-03-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 26 513 9.4E-197 T 09-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 205 211 - T 09-03-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_RS12495 72c29c80dbdcf16859f34bc826a8e9d3 514 Gene3D G3DSA:3.40.50.720 25 214 1.7E-66 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21375 b72382aa6dfee2e075979ead0e476c1a 323 Gene3D G3DSA:3.10.129.10 163 321 2.2E-56 T 09-03-2017 IPR029069 HotDog domain UA74_RS21375 b72382aa6dfee2e075979ead0e476c1a 323 SUPERFAMILY SSF54637 43 153 1.17E-40 T 09-03-2017 IPR029069 HotDog domain UA74_RS21375 b72382aa6dfee2e075979ead0e476c1a 323 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 51 320 3.3E-95 T 09-03-2017 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-75105 UA74_RS21375 b72382aa6dfee2e075979ead0e476c1a 323 Gene3D G3DSA:3.10.129.10 44 154 2.4E-47 T 09-03-2017 IPR029069 HotDog domain UA74_RS21375 b72382aa6dfee2e075979ead0e476c1a 323 SUPERFAMILY SSF54637 155 320 1.33E-52 T 09-03-2017 IPR029069 HotDog domain UA74_RS21375 b72382aa6dfee2e075979ead0e476c1a 323 Pfam PF13622 Thioesterase-like superfamily 70 318 4.4E-60 T 09-03-2017 UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.7E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.4E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.4E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.4E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06665 948af2661075360f95bfb27175992848 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS06665 948af2661075360f95bfb27175992848 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.8E-60 T 09-03-2017 UA74_RS06665 948af2661075360f95bfb27175992848 253 SUPERFAMILY SSF51735 7 252 1.72E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06665 948af2661075360f95bfb27175992848 253 Gene3D G3DSA:3.40.50.720 2 252 1.8E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.6E-15 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 Gene3D G3DSA:3.40.50.2300 55 170 7.1E-41 T 09-03-2017 UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 SUPERFAMILY SSF53822 62 325 7.26E-61 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 Gene3D G3DSA:3.40.50.2300 171 301 2.2E-40 T 09-03-2017 UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 SMART SM00354 2 72 1.0E-26 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 SUPERFAMILY SSF47413 3 59 2.73E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 Gene3D G3DSA:1.10.260.40 3 54 1.9E-22 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22255 4cd47e01beba96970a0053cf7e43e28f 328 Pfam PF13377 Periplasmic binding protein-like domain 165 323 3.9E-36 T 09-03-2017 UA74_RS02195 a6754fccb967b7802f8dfce209dc559b 408 Gene3D G3DSA:3.40.50.1110 207 400 2.5E-23 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS02195 a6754fccb967b7802f8dfce209dc559b 408 SUPERFAMILY SSF52266 206 400 2.14E-34 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS02195 a6754fccb967b7802f8dfce209dc559b 408 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 210 394 1.3E-18 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS24055 a087bbf74f6c492ea244cc55d2055b30 424 Gene3D G3DSA:3.30.565.10 303 381 8.8E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS24055 a087bbf74f6c492ea244cc55d2055b30 424 Pfam PF07730 Histidine kinase 213 276 7.8E-17 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS24055 a087bbf74f6c492ea244cc55d2055b30 424 SUPERFAMILY SSF55874 299 417 8.28E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS30235 a3b3a89ab6502731dbc11d1ecb3ec46c 266 Gene3D G3DSA:3.40.50.1820 18 263 2.0E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS30235 a3b3a89ab6502731dbc11d1ecb3ec46c 266 SUPERFAMILY SSF53474 16 262 1.36E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS30235 a3b3a89ab6502731dbc11d1ecb3ec46c 266 Pfam PF00561 alpha/beta hydrolase fold 23 248 2.3E-21 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS30235 a3b3a89ab6502731dbc11d1ecb3ec46c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.8E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS30235 a3b3a89ab6502731dbc11d1ecb3ec46c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.8E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS30235 a3b3a89ab6502731dbc11d1ecb3ec46c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.8E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS29815 fbb6f5c26442fd594c38450b98ee9e62 283 SMART SM00530 16 71 5.0E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS29815 fbb6f5c26442fd594c38450b98ee9e62 283 Gene3D G3DSA:1.10.260.40 3 70 1.2E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS29815 fbb6f5c26442fd594c38450b98ee9e62 283 Pfam PF13560 Helix-turn-helix domain 13 73 6.9E-9 T 09-03-2017 UA74_RS29815 fbb6f5c26442fd594c38450b98ee9e62 283 SUPERFAMILY SSF47413 9 70 1.18E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 391 36.46 T 09-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF49493 239 292 2.09E-21 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF49493 139 195 2.09E-21 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:2.60.260.20 136 167 1.0E-20 T 09-03-2017 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:2.60.260.20 236 280 1.0E-20 T 09-03-2017 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 375 1.3E-115 T 09-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 47 67 2.5E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 12 30 2.5E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 67 86 2.5E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 30 45 2.5E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:2.60.260.20 282 358 6.0E-20 T 09-03-2017 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Pfam PF00684 DnaJ central domain 173 233 2.1E-13 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:1.10.287.110 4 89 2.9E-28 T 09-03-2017 IPR001623 DnaJ domain UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF57938 160 235 6.15E-20 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF49493 285 368 1.83E-18 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:2.10.230.10 168 235 3.3E-22 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 SMART SM00271 9 67 9.9E-26 T 09-03-2017 IPR001623 DnaJ domain UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF46565 9 109 4.58E-28 T 09-03-2017 IPR001623 DnaJ domain UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Pfam PF01556 DnaJ C terminal domain 146 358 6.8E-36 T 09-03-2017 IPR002939 Chaperone DnaJ, C-terminal UA74_RS29870 fd7d7d73d96ac30f4861b33a0cf478f0 395 Pfam PF00226 DnaJ domain 10 72 9.1E-25 T 09-03-2017 IPR001623 DnaJ domain UA74_RS22770 14b1e74e65c86ca088d271889ce7ab7e 335 SUPERFAMILY SSF51604 72 294 2.36E-49 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS22770 14b1e74e65c86ca088d271889ce7ab7e 335 SMART SM00922 83 183 5.3E-21 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS22770 14b1e74e65c86ca088d271889ce7ab7e 335 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 5 291 23.151 T 09-03-2017 IPR010196 o-succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS22770 14b1e74e65c86ca088d271889ce7ab7e 335 Pfam PF13378 Enolase C-terminal domain-like 88 293 7.0E-35 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS22770 14b1e74e65c86ca088d271889ce7ab7e 335 Gene3D G3DSA:3.30.390.10 8 97 6.1E-44 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS22770 14b1e74e65c86ca088d271889ce7ab7e 335 Gene3D G3DSA:3.20.20.120 98 322 8.5E-54 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:3.30.230.70 340 574 9.5E-80 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:3.30.230.70 10 248 4.8E-82 T 09-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF54211 323 519 1.97E-42 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Pfam PF03725 3' exoribonuclease family, domain 2 487 561 1.6E-5 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Pfam PF00575 S1 RNA binding domain 652 721 1.6E-13 T 09-03-2017 IPR003029 S1 domain GO:0003676 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SMART SM00316 653 724 7.2E-16 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Pfam PF00013 KH domain 587 644 5.0E-10 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SMART SM00322 583 648 1.8E-10 T 09-03-2017 IPR004087 K Homology domain GO:0003676 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:3.30.1370.10 582 654 1.0E-21 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Pfam PF01138 3' exoribonuclease family, domain 1 21 152 8.7E-17 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Pfam PF01138 3' exoribonuclease family, domain 1 352 484 8.8E-15 T 09-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:1.10.10.400 263 339 2.0E-22 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF55666 153 259 6.71E-27 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF46915 264 349 2.43E-15 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 6 723 0.0 T 09-03-2017 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF54791 586 672 2.18E-17 T 09-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 269 347 2.4E-18 T 09-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF55666 478 577 3.11E-24 T 09-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF50249 653 721 1.64E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 722 9.7E-264 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 727 27.002 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 PIRSF PIRSF005499 8 750 4.8E-282 T 09-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:2.40.50.140 655 725 7.3E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS09480 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF54211 11 152 2.83E-45 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS08380 ed754084cea5af9aeef86548d4c35ff0 789 Pfam PF00753 Metallo-beta-lactamase superfamily 541 719 5.0E-8 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS08380 ed754084cea5af9aeef86548d4c35ff0 789 SUPERFAMILY SSF56281 526 777 4.32E-39 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS08380 ed754084cea5af9aeef86548d4c35ff0 789 Gene3D G3DSA:3.60.15.10 524 769 3.2E-23 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS08380 ed754084cea5af9aeef86548d4c35ff0 789 SMART SM00849 539 739 8.7E-6 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS08380 ed754084cea5af9aeef86548d4c35ff0 789 Pfam PF03772 Competence protein 232 497 1.6E-50 T 09-03-2017 IPR004477 ComEC/Rec2-related protein UA74_RS08380 ed754084cea5af9aeef86548d4c35ff0 789 Pfam PF13567 Domain of unknown function (DUF4131) 34 180 9.2E-8 T 09-03-2017 IPR025405 Domain of unknown function DUF4131 UA74_RS08380 ed754084cea5af9aeef86548d4c35ff0 789 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 254 423 6.5E-17 T 09-03-2017 IPR004477 ComEC/Rec2-related protein UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF52777 1846 2021 5.0E-40 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.980 2470 2636 2.4E-34 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1458 1652 1.3E-46 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.47.10 9 275 1.4E-94 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF53474 2942 3159 3.59E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.366.10 737 860 3.1E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.366.10 541 669 3.1E-70 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF51735 1454 1712 1.74E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF13745 HxxPF-repeated domain 2162 2253 1.2E-17 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 175 191 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF13193 AMP-binding enzyme C-terminal domain 2762 2837 4.1E-10 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2341 2778 4.8E-117 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 549 846 3.2E-104 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF55048 672 736 5.49E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.1820 3097 3159 1.5E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.1820 2948 3043 1.5E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00824 Thioesterase 2954 3148 8.3E-5 T 09-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF47336 2855 2928 3.4E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF52151 738 833 1.41E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF52151 545 674 1.41E-63 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:2.30.38.10 2637 2743 6.0E-24 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00826 907 1066 8.8E-45 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00698 Acyl transferase domain 547 864 3.1E-71 T 09-03-2017 IPR014043 Acyl transferase UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.47.10 276 440 2.9E-61 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF47336 1747 1819 7.2E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00550 Phosphopantetheine attachment site 2867 2927 4.6E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00550 Phosphopantetheine attachment site 1752 1807 1.6E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00975 Thioesterase domain 2952 3045 1.6E-19 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00668 Condensation domain 1843 2139 5.4E-69 T 09-03-2017 IPR001242 Condensation domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.30.70.250 672 729 6.5E-5 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 270 387 2.0E-41 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF14765 Polyketide synthase dehydratase 907 1188 6.1E-71 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:1.10.1200.10 1747 1815 1.7E-8 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:1.10.1200.10 2867 2929 4.2E-19 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 262 7.4E-81 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 391 504 1.0E-12 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2462 2473 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00825 Beta-ketoacyl synthase 13 440 8.2E-209 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF53901 415 436 1.09E-96 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF53901 158 383 1.09E-96 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF53901 9 131 1.09E-96 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF52777 2027 2274 5.11E-56 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00501 AMP-binding enzyme 2310 2754 5.2E-83 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.980 2304 2469 2.3E-44 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF51735 1195 1443 1.1E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00823 Phosphopantetheine attachment site 2863 2932 0.0023 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00823 Phosphopantetheine attachment site 1748 1819 3.3E-9 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.720 1458 1688 5.4E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF08659 KR domain 1458 1650 1.0E-56 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.30.300.30 2750 2866 3.6E-40 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF56801 2270 2689 6.8E-145 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF56801 2724 2876 6.8E-145 T 09-03-2017 UA74_RS18040 d108006b43f32b0d2ed68cbae0b6d174 3167 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1774 1789 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS02505 f08f75c9900a733227cafc5dcc38e322 303 Pfam PF05138 Phenylacetic acid catabolic protein 42 303 1.7E-75 T 09-03-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UA74_RS02505 f08f75c9900a733227cafc5dcc38e322 303 SUPERFAMILY SSF47240 44 297 2.3E-60 T 09-03-2017 IPR009078 Ferritin-like superfamily UA74_RS02505 f08f75c9900a733227cafc5dcc38e322 303 Gene3D G3DSA:1.20.1260.10 38 303 1.1E-80 T 09-03-2017 IPR012347 Ferritin-related UA74_RS02505 f08f75c9900a733227cafc5dcc38e322 303 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 52 303 4.4E-70 T 09-03-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UA74_RS02505 f08f75c9900a733227cafc5dcc38e322 303 PIRSF PIRSF037834 37 303 1.3E-86 T 09-03-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 SUPERFAMILY SSF54736 55 127 1.12E-20 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 127 6.3E-26 T 09-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 127 1.4E-46 T 09-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 SUPERFAMILY SSF48300 5 62 8.89E-13 T 09-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 102 3.0E-13 T 09-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 Gene3D G3DSA:3.30.1390.10 53 127 2.2E-29 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 127 23.102 T 09-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 Gene3D G3DSA:1.20.5.710 3 52 5.0E-16 T 09-03-2017 UA74_RS02845 76238fdef7e4a98a65fd2e7cb28ce522 127 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 7 53 1.2E-15 T 09-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08740 398de6b0a2f509e17eee41665611da05 88 Pfam PF01476 LysM domain 33 80 6.0E-5 T 09-03-2017 IPR018392 LysM domain UA74_RS08740 398de6b0a2f509e17eee41665611da05 88 Gene3D G3DSA:3.10.350.10 33 80 5.1E-5 T 09-03-2017 IPR018392 LysM domain UA74_RS25775 43c5caa2e836e457535d8d2758e2c48a 203 Pfam PF02620 Uncharacterized ACR, COG1399 75 185 2.2E-27 T 09-03-2017 IPR003772 Protein of unknown function DUF177 UA74_RS22375 267f9450fb0e38135a03335531339471 421 Gene3D G3DSA:3.20.20.80 337 356 1.5E-9 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS22375 267f9450fb0e38135a03335531339471 421 Gene3D G3DSA:3.20.20.80 33 266 1.5E-9 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS22375 267f9450fb0e38135a03335531339471 421 Pfam PF12876 Sugar-binding cellulase-like 15 177 1.4E-12 T 09-03-2017 IPR024778 Putative cellulase UA74_RS22375 267f9450fb0e38135a03335531339471 421 SUPERFAMILY SSF51445 305 360 1.92E-13 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS22375 267f9450fb0e38135a03335531339471 421 SUPERFAMILY SSF51445 16 244 1.92E-13 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS21345 6229ecf8605340e5679e9e53e13ae1e7 267 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 127 1.3E-12 T 09-03-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain UA74_RS21345 6229ecf8605340e5679e9e53e13ae1e7 267 Gene3D G3DSA:3.30.530.20 3 136 2.3E-7 T 09-03-2017 IPR023393 START-like domain UA74_RS21345 6229ecf8605340e5679e9e53e13ae1e7 267 SUPERFAMILY SSF55961 3 136 1.1E-19 T 09-03-2017 UA74_RS21225 bcafd72ea52d414488ddbd432219b687 101 Gene3D G3DSA:4.10.830.10 43 101 5.1E-30 T 09-03-2017 UA74_RS21225 bcafd72ea52d414488ddbd432219b687 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.281 T 09-03-2017 IPR023036 Ribosomal protein S14, bacterial/plastid UA74_RS21225 bcafd72ea52d414488ddbd432219b687 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.0E-25 T 09-03-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21225 bcafd72ea52d414488ddbd432219b687 101 SUPERFAMILY SSF57716 2 101 1.21E-34 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 SUPERFAMILY SSF51905 3 199 1.81E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 Pfam PF04324 BFD-like [2Fe-2S] binding domain 425 469 9.2E-10 T 09-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.9E-16 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.9E-16 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.9E-16 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.9E-16 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 SUPERFAMILY SSF51905 154 309 1.09E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 301 5.1E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 Gene3D G3DSA:3.50.50.60 109 308 5.6E-41 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 Gene3D G3DSA:3.50.50.60 3 108 4.3E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.9E-9 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 2.9E-9 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 2.9E-9 T 09-03-2017 UA74_RS09465 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 2.9E-9 T 09-03-2017 UA74_RS08460 2c923849be40b4fa48e69b9ac4aa0df4 273 Pfam PF07070 SpoOM protein 2 222 5.5E-53 T 09-03-2017 IPR009776 Sporulation stage 0, protein M UA74_RS25695 202e3bdfdfd1458c1afd9cba16f134ae 290 Gene3D G3DSA:1.10.260.40 9 70 4.1E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25695 202e3bdfdfd1458c1afd9cba16f134ae 290 SUPERFAMILY SSF47413 13 70 7.74E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25695 202e3bdfdfd1458c1afd9cba16f134ae 290 Pfam PF13560 Helix-turn-helix domain 15 75 1.1E-11 T 09-03-2017 UA74_RS27075 f9ed89cb2cbb36a0922fe9fed5201fd2 547 Gene3D G3DSA:3.90.226.10 12 274 2.2E-74 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS27075 f9ed89cb2cbb36a0922fe9fed5201fd2 547 Gene3D G3DSA:3.90.226.10 294 547 1.5E-99 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS27075 f9ed89cb2cbb36a0922fe9fed5201fd2 547 SUPERFAMILY SSF52096 24 274 1.99E-74 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS27075 f9ed89cb2cbb36a0922fe9fed5201fd2 547 Pfam PF01039 Carboxyl transferase domain 46 545 6.1E-191 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS27075 f9ed89cb2cbb36a0922fe9fed5201fd2 547 SUPERFAMILY SSF52096 262 547 8.13E-88 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS28265 522cf5a5abcfed784eaa2f05b8e3fa85 537 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 494 1.4E-88 T 09-03-2017 IPR007795 Type VII secretion system EccB UA74_RS28265 522cf5a5abcfed784eaa2f05b8e3fa85 537 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 507 5.4E-113 T 09-03-2017 IPR007795 Type VII secretion system EccB UA74_RS15260 39e935e140e74568f2e827c32ff3e09c 114 SUPERFAMILY SSF50324 7 95 2.35E-13 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS15260 39e935e140e74568f2e827c32ff3e09c 114 Gene3D G3DSA:3.90.80.10 18 95 1.9E-9 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS15260 39e935e140e74568f2e827c32ff3e09c 114 Pfam PF00719 Inorganic pyrophosphatase 26 96 1.7E-6 T 09-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 UA74_RS25720 cbe1bb79a9b69f23054691d1aaa099be 231 Pfam PF00188 Cysteine-rich secretory protein family 120 229 1.3E-18 T 09-03-2017 IPR014044 CAP domain UA74_RS25720 cbe1bb79a9b69f23054691d1aaa099be 231 SUPERFAMILY SSF55797 113 230 4.88E-23 T 09-03-2017 IPR014044 CAP domain UA74_RS25720 cbe1bb79a9b69f23054691d1aaa099be 231 Gene3D G3DSA:3.40.33.10 109 222 1.0E-11 T 09-03-2017 IPR014044 CAP domain UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 626 727 1.1E-22 T 09-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF81296 116 223 3.67E-30 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Gene3D G3DSA:3.20.20.80 248 609 5.4E-90 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF51011 622 728 6.76E-31 T 09-03-2017 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Pfam PF00128 Alpha amylase, catalytic domain 274 342 1.0E-9 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Gene3D G3DSA:2.60.40.1180 622 727 4.8E-37 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Gene3D G3DSA:2.60.40.10 112 224 2.5E-36 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Gene3D G3DSA:2.60.40.10 17 105 1.5E-16 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 124 210 3.2E-20 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF51445 177 614 8.9E-114 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 100 728 43.874 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 PIRSF PIRSF000463 10 729 4.6E-281 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF81296 18 113 1.61E-18 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 108 725 4.3E-275 T 09-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07370 553edc381a03f4cb7cb1bcd4d6bb368e 729 SMART SM00642 253 594 5.3E-8 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 SUPERFAMILY SSF49464 840 920 1.18E-10 T 09-03-2017 IPR008969 Carboxypeptidase-like, regulatory domain UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 PRINTS PR00723 Subtilisin serine protease family (S8) signature 407 423 1.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 PRINTS PR00723 Subtilisin serine protease family (S8) signature 231 244 1.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 PRINTS PR00723 Subtilisin serine protease family (S8) signature 177 196 1.1E-15 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 SUPERFAMILY SSF49464 485 560 1.1E-12 T 09-03-2017 IPR008969 Carboxypeptidase-like, regulatory domain UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Pfam PF11721 Di-glucose binding within endoplasmic reticulum 1307 1444 3.0E-19 T 09-03-2017 IPR021720 Malectin Reactome: R-HSA-532668 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 SUPERFAMILY SSF52743 158 475 2.23E-58 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Gene3D G3DSA:2.60.40.360 1238 1299 1.4E-4 T 09-03-2017 IPR008962 PapD-like UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 SUPERFAMILY SSF49785 1314 1465 2.38E-9 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 235 245 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Pfam PF13620 Carboxypeptidase regulatory-like domain 840 919 9.4E-9 T 09-03-2017 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Pfam PF13620 Carboxypeptidase regulatory-like domain 485 561 4.2E-12 T 09-03-2017 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Pfam PF13620 Carboxypeptidase regulatory-like domain 567 643 1.4E-9 T 09-03-2017 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Gene3D G3DSA:2.60.120.360 1314 1463 7.4E-10 T 09-03-2017 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Pfam PF00082 Subtilase family 177 448 3.2E-38 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Gene3D G3DSA:3.40.50.200 157 474 1.1E-67 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 SUPERFAMILY SSF49452 562 643 5.49E-10 T 09-03-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Gene3D G3DSA:2.60.40.1120 485 561 1.3E-16 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Gene3D G3DSA:2.60.40.1120 567 643 7.1E-8 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 Gene3D G3DSA:2.60.40.1120 840 919 2.5E-10 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 SUPERFAMILY SSF63829 1070 1233 1.11E-8 T 09-03-2017 UA74_RS11275 1fa2af9b0df51e6c63870eb4c7d4db5e 1466 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 408 418 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS22525 07cbf5d7c4df5628b1adbff04fdcaa1e 132 SUPERFAMILY SSF142906 1 118 2.22E-33 T 09-03-2017 UA74_RS22525 07cbf5d7c4df5628b1adbff04fdcaa1e 132 Pfam PF04237 YjbR 11 103 1.6E-25 T 09-03-2017 IPR007351 Uncharacterised protein YjbR UA74_RS14725 7872cf11187714a6455c2431add089b1 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 100 3.5E-14 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS14725 7872cf11187714a6455c2431add089b1 144 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 4 131 8.4E-32 T 09-03-2017 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family UA74_RS14725 7872cf11187714a6455c2431add089b1 144 SUPERFAMILY SSF50475 6 138 3.74E-23 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS14725 7872cf11187714a6455c2431add089b1 144 Gene3D G3DSA:2.30.110.10 9 133 2.9E-20 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS15685 3876bbd9eb9678d711484b7c8dbc4d7f 232 Gene3D G3DSA:3.40.50.1240 2 203 5.5E-39 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS15685 3876bbd9eb9678d711484b7c8dbc4d7f 232 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 206 7.7E-96 T 09-03-2017 IPR022492 Phosphomutase MSMEG4193, putative UA74_RS15685 3876bbd9eb9678d711484b7c8dbc4d7f 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 200 5.8E-43 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS15685 3876bbd9eb9678d711484b7c8dbc4d7f 232 SMART SM00855 3 161 2.5E-16 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS15685 3876bbd9eb9678d711484b7c8dbc4d7f 232 SUPERFAMILY SSF53254 1 200 5.57E-40 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS21265 9ef5e4058cc2c37c946054f7b0be9e90 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 21 104 2.3E-29 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_RS21265 9ef5e4058cc2c37c946054f7b0be9e90 114 Pfam PF12823 Domain of unknown function (DUF3817) 19 106 3.5E-27 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 2.6E-21 T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 24.923 T 09-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 Gene3D G3DSA:3.40.5.10 1 51 1.4E-22 T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 09-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 7.6E-23 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 SUPERFAMILY SSF55658 1 55 4.71E-17 T 09-03-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 4.0E-34 T 09-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 SUPERFAMILY SSF55653 58 148 3.27E-21 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal UA74_RS30180 3a5c56e6e42c2e7757fdcb0423f03618 151 Gene3D G3DSA:3.10.430.100 61 149 4.0E-24 T 09-03-2017 IPR020069 Ribosomal protein L9, C-terminal UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF52151 552 683 3.14E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF52151 744 835 3.14E-67 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1125 1305 8.8E-48 T 09-03-2017 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF51735 1121 1354 3.8E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.30.70.250 682 743 5.9E-7 T 09-03-2017 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF51735 898 1112 1.23E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF55048 681 743 1.44E-11 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF08659 KR domain 1125 1303 1.4E-59 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF47336 1403 1488 5.89E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00825 Beta-ketoacyl synthase 37 448 9.4E-199 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.366.10 549 678 4.0E-72 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.366.10 744 858 4.0E-72 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.47.10 283 448 7.9E-65 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 555 845 1.2E-112 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF53901 33 388 4.88E-96 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF00698 Acyl transferase domain 554 847 7.4E-54 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.47.10 37 282 1.4E-82 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF00550 Phosphopantetheine attachment site 1412 1477 2.9E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 183 199 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 398 519 7.4E-15 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:1.10.1200.10 1408 1481 3.4E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.50.720 1124 1342 4.2E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SMART SM01294 1410 1477 4.2E-4 T 09-03-2017 UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 395 3.5E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 270 5.7E-76 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1436 1451 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16490 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00823 Phosphopantetheine attachment site 1409 1481 6.0E-30 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 09-03-2017 IPR013852 Translation elongation factor P/YeiP, conserved site UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 119 3.7E-21 T 09-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.2E-26 T 09-03-2017 IPR013185 Translation elongation factor, KOW-like UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SMART SM00841 129 184 9.2E-30 T 09-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SUPERFAMILY SSF50104 2 63 3.79E-20 T 09-03-2017 IPR008991 Translation protein SH3-like domain UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SUPERFAMILY SSF50249 129 185 3.6E-16 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SUPERFAMILY SSF50249 65 126 1.29E-17 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 9.5E-24 T 09-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SMART SM01185 67 121 1.8E-26 T 09-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 PIRSF PIRSF005901 1 186 1.2E-64 T 09-03-2017 IPR020599 Translation elongation factor P/YeiP UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Gene3D G3DSA:2.30.30.30 3 63 3.0E-31 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.4E-75 T 09-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 48.659 T 09-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Gene3D G3DSA:2.40.50.140 64 127 2.0E-24 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS12260 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Gene3D G3DSA:2.40.50.140 128 185 4.8E-26 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 8.4E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.4E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 8.4E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 8.4E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 8.4E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 SUPERFAMILY SSF51735 3 252 1.18E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 Gene3D G3DSA:3.40.50.720 4 260 1.5E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06110 aeff210b8431f3543764cbb30f2b6705 305 Pfam PF00106 short chain dehydrogenase 8 209 1.9E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24025 e0ebfee6c105136b4cc5710268f7d8c8 415 SMART SM00421 346 403 3.2E-4 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24025 e0ebfee6c105136b4cc5710268f7d8c8 415 Gene3D G3DSA:1.10.10.10 1 83 2.6E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24025 e0ebfee6c105136b4cc5710268f7d8c8 415 Gene3D G3DSA:1.10.10.10 355 408 9.8E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24025 e0ebfee6c105136b4cc5710268f7d8c8 415 Pfam PF00196 Bacterial regulatory proteins, luxR family 356 403 8.2E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24025 e0ebfee6c105136b4cc5710268f7d8c8 415 SUPERFAMILY SSF46785 2 73 5.46E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24025 e0ebfee6c105136b4cc5710268f7d8c8 415 SUPERFAMILY SSF46894 353 409 1.02E-8 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 Pfam PF05406 WGR domain 12 79 4.3E-15 T 09-03-2017 IPR008893 WGR domain UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 Gene3D G3DSA:2.20.140.10 13 81 3.1E-19 T 09-03-2017 IPR008893 WGR domain UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 SUPERFAMILY SSF50998 102 375 5.1E-17 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 Pfam PF13360 PQQ-like domain 249 375 1.8E-9 T 09-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 SUPERFAMILY SSF142921 13 78 2.09E-9 T 09-03-2017 IPR008893 WGR domain UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 SMART SM00773 10 83 5.1E-17 T 09-03-2017 IPR008893 WGR domain UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 Gene3D G3DSA:2.140.10.10 279 374 2.0E-10 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain UA74_RS24175 660fbf615cc5387a813763f73c1cef85 484 Gene3D G3DSA:2.140.10.10 96 269 2.1E-4 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain UA74_RS27420 ce643fcfb4814bd824f2092a4150e832 258 Gene3D G3DSA:3.40.50.1580 3 255 2.7E-88 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS27420 ce643fcfb4814bd824f2092a4150e832 258 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 19 255 8.4E-76 T 09-03-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 UA74_RS27420 ce643fcfb4814bd824f2092a4150e832 258 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 73 114 - T 09-03-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 UA74_RS27420 ce643fcfb4814bd824f2092a4150e832 258 PIRSF PIRSF000477 1 258 2.2E-89 T 09-03-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 UA74_RS27420 ce643fcfb4814bd824f2092a4150e832 258 Pfam PF01048 Phosphorylase superfamily 20 255 4.7E-40 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS27420 ce643fcfb4814bd824f2092a4150e832 258 SUPERFAMILY SSF53167 4 255 1.35E-77 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS27420 ce643fcfb4814bd824f2092a4150e832 258 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 20 255 1.1E-96 T 09-03-2017 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 SUPERFAMILY SSF55874 231 375 1.27E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 376 1.9E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 SMART SM00387 267 378 4.0E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 356 1.8E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1 12 1.8E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 1.8E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 1.8E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 Gene3D G3DSA:3.30.565.10 229 377 1.4E-32 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 SUPERFAMILY SSF158472 104 153 1.57E-7 T 09-03-2017 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 SMART SM00388 157 224 2.4E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 SMART SM00304 103 156 1.3E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 Gene3D G3DSA:1.10.287.130 147 220 4.8E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 Pfam PF00672 HAMP domain 85 152 4.7E-14 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 223 5.3E-13 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS08610 999a45c078e664b969ab6288da4b5ca1 378 SUPERFAMILY SSF47384 140 222 9.22E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS16910 d3908a2fc779e3476995b281573d8dbd 487 ProSitePatterns PS00571 Amidases signature. 149 180 - T 09-03-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UA74_RS16910 d3908a2fc779e3476995b281573d8dbd 487 Gene3D G3DSA:3.90.1300.10 5 475 8.4E-108 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS16910 d3908a2fc779e3476995b281573d8dbd 487 Pfam PF01425 Amidase 31 459 3.2E-84 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS16910 d3908a2fc779e3476995b281573d8dbd 487 SUPERFAMILY SSF75304 5 480 7.19E-112 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 SUPERFAMILY SSF69065 12 170 4.19E-43 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 Pfam PF00035 Double-stranded RNA binding motif 170 235 2.5E-15 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 SMART SM00535 27 163 1.8E-50 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 SMART SM00358 170 236 4.6E-22 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 27 233 3.2E-68 T 09-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 SUPERFAMILY SSF54768 124 235 1.45E-24 T 09-03-2017 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 Gene3D G3DSA:3.30.160.20 168 235 5.5E-24 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 ProSitePatterns PS00517 Ribonuclease III family signature. 49 57 - T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 Gene3D G3DSA:1.10.1520.10 25 157 8.5E-42 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 Pfam PF14622 Ribonuclease-III-like 27 152 8.0E-36 T 09-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 UA74_RS25765 8c61cc0215a70c22f86a88b9d9c8cbe8 247 Hamap MF_00104 Ribonuclease 3 [rnc]. 16 232 29.199 T 09-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 Gene3D G3DSA:1.10.10.10 113 167 4.8E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 SUPERFAMILY SSF88659 88 166 1.33E-12 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 Gene3D G3DSA:3.10.450.50 177 292 2.4E-12 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 166 2.1E-17 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 SUPERFAMILY SSF88946 15 95 1.73E-13 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 Gene3D G3DSA:1.10.1740.10 15 80 4.0E-14 T 09-03-2017 UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 SUPERFAMILY SSF54427 178 294 1.0E-14 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 Pfam PF04542 Sigma-70 region 2 15 78 1.8E-15 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 Pfam PF08281 Sigma-70, region 4 114 165 6.0E-13 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10005 6ad89703ce35db92a80a46044e0ab86f 299 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 14 293 8.7E-110 T 09-03-2017 IPR014303 RNA polymerase sigma-70, ECF type UA74_RS03870 8dd461a5ec876ffbd4473eb445d6c654 385 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS03870 8dd461a5ec876ffbd4473eb445d6c654 385 Gene3D G3DSA:3.90.1150.10 254 384 4.5E-47 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS03870 8dd461a5ec876ffbd4473eb445d6c654 385 Gene3D G3DSA:3.40.640.10 10 253 5.9E-105 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS03870 8dd461a5ec876ffbd4473eb445d6c654 385 PIRSF PIRSF001434 2 385 3.7E-144 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS03870 8dd461a5ec876ffbd4473eb445d6c654 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 384 6.9E-148 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS03870 8dd461a5ec876ffbd4473eb445d6c654 385 SUPERFAMILY SSF53383 14 384 1.24E-126 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 Pfam PF01494 FAD binding domain 7 327 2.0E-24 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 SUPERFAMILY SSF51905 7 176 8.07E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 SUPERFAMILY SSF51905 276 377 8.07E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.6E-18 T 09-03-2017 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.6E-18 T 09-03-2017 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 2.6E-18 T 09-03-2017 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 2.6E-18 T 09-03-2017 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 Gene3D G3DSA:3.50.50.60 277 346 2.6E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22015 26172246544bd669dc098d8bbd4b66e2 407 Gene3D G3DSA:3.50.50.60 7 181 2.6E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25785 d0b4f18a1b6b81e2a074ee51e8a1be1d 143 Pfam PF00545 ribonuclease 59 137 1.7E-27 T 09-03-2017 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 UA74_RS25785 d0b4f18a1b6b81e2a074ee51e8a1be1d 143 Gene3D G3DSA:3.10.450.30 51 140 1.1E-37 T 09-03-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 UA74_RS25785 d0b4f18a1b6b81e2a074ee51e8a1be1d 143 SUPERFAMILY SSF53933 50 140 7.37E-35 T 09-03-2017 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 UA74_RS18170 b39b7caa3755b9bc54087c0a42d5b618 301 Pfam PF00005 ABC transporter 21 161 6.7E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS18170 b39b7caa3755b9bc54087c0a42d5b618 301 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS18170 b39b7caa3755b9bc54087c0a42d5b618 301 SMART SM00382 29 216 1.0E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS18170 b39b7caa3755b9bc54087c0a42d5b618 301 Gene3D G3DSA:3.40.50.300 4 222 2.6E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18170 b39b7caa3755b9bc54087c0a42d5b618 301 SUPERFAMILY SSF52540 5 220 2.21E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14695 d12bdf13a163799dfcb0a424492e4a8a 210 Gene3D G3DSA:3.40.630.30 119 186 1.5E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14695 d12bdf13a163799dfcb0a424492e4a8a 210 Gene3D G3DSA:3.40.630.30 2 73 1.5E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14695 d12bdf13a163799dfcb0a424492e4a8a 210 SUPERFAMILY SSF55729 2 186 3.26E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14695 d12bdf13a163799dfcb0a424492e4a8a 210 Pfam PF00583 Acetyltransferase (GNAT) family 134 183 1.3E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 SMART SM00633 44 300 4.8E-131 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 Gene3D G3DSA:2.60.40.290 322 408 6.4E-19 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 SUPERFAMILY SSF51445 4 301 2.98E-107 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 226 236 - T 09-03-2017 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 PRINTS PR00134 Glycosyl hydrolase family 10 signature 75 87 4.7E-17 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 PRINTS PR00134 Glycosyl hydrolase family 10 signature 192 204 4.7E-17 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 PRINTS PR00134 Glycosyl hydrolase family 10 signature 117 128 4.7E-17 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 PRINTS PR00134 Glycosyl hydrolase family 10 signature 162 173 4.7E-17 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 Gene3D G3DSA:3.20.20.80 4 303 2.7E-114 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 Pfam PF00331 Glycosyl hydrolase family 10 4 298 9.5E-110 T 09-03-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 SUPERFAMILY SSF49384 322 410 2.44E-15 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS05420 11c12dd9b5bf5e16b449a4949c059495 410 SMART SM00637 324 407 2.3E-10 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS23090 f9fad477204445af15261b2d295b9544 218 SUPERFAMILY SSF52540 14 173 8.55E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23090 f9fad477204445af15261b2d295b9544 218 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 14 159 3.4E-27 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_RS23090 f9fad477204445af15261b2d295b9544 218 Pfam PF02223 Thymidylate kinase 19 167 1.7E-26 T 09-03-2017 UA74_RS23090 f9fad477204445af15261b2d295b9544 218 Hamap MF_00165 Thymidylate kinase [tmk]. 15 210 15.484 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_RS23090 f9fad477204445af15261b2d295b9544 218 Gene3D G3DSA:3.40.50.300 14 211 1.1E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07310 576ce43412407590c77d531bad25467d 291 SUPERFAMILY SSF56235 8 204 2.85E-47 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS07310 576ce43412407590c77d531bad25467d 291 Gene3D G3DSA:3.60.20.10 7 204 4.1E-51 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS07310 576ce43412407590c77d531bad25467d 291 Pfam PF06267 Family of unknown function (DUF1028) 8 193 1.2E-47 T 09-03-2017 IPR010430 Protein of unknown function DUF1028 UA74_RS14535 0a70a4702b769153431964b8ef1ffcd2 266 Pfam PF00005 ABC transporter 18 165 9.3E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14535 0a70a4702b769153431964b8ef1ffcd2 266 SUPERFAMILY SSF52540 1 227 4.51E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14535 0a70a4702b769153431964b8ef1ffcd2 266 SMART SM00382 26 214 3.3E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14535 0a70a4702b769153431964b8ef1ffcd2 266 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS14535 0a70a4702b769153431964b8ef1ffcd2 266 Gene3D G3DSA:3.40.50.300 1 234 2.4E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03580 2a75103212937a77944346af5b616220 417 SUPERFAMILY SSF103473 15 406 1.28E-42 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS03580 2a75103212937a77944346af5b616220 417 Gene3D G3DSA:1.20.1250.20 15 197 3.7E-20 T 09-03-2017 UA74_RS03580 2a75103212937a77944346af5b616220 417 Gene3D G3DSA:1.20.1250.20 228 404 2.3E-12 T 09-03-2017 UA74_RS03580 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 269 286 6.7E-5 T 09-03-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_RS03580 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 21 43 6.7E-5 T 09-03-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_RS03580 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 177 194 6.7E-5 T 09-03-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_RS03580 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 84 102 6.7E-5 T 09-03-2017 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_RS03580 2a75103212937a77944346af5b616220 417 Pfam PF05977 Transmembrane secretion effector 15 399 3.8E-29 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 Pfam PF01546 Peptidase family M20/M25/M40 108 416 3.3E-28 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 SUPERFAMILY SSF55031 216 333 7.78E-21 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 PIRSF PIRSF005962 42 423 5.4E-104 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 54 408 7.7E-102 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 SUPERFAMILY SSF53187 42 231 5.18E-73 T 09-03-2017 UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 SUPERFAMILY SSF53187 332 420 5.18E-73 T 09-03-2017 UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 Gene3D G3DSA:3.40.630.10 41 212 7.4E-91 T 09-03-2017 UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 Gene3D G3DSA:3.40.630.10 332 421 7.4E-91 T 09-03-2017 UA74_RS27220 63dffcf2d095818ba41f6ab19cc3e67e 437 Gene3D G3DSA:3.30.70.360 216 331 4.4E-27 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS12910 3cb3ff66e82411ba610ead3b0756e6c3 661 Pfam PF03109 ABC1 family 207 310 1.2E-29 T 09-03-2017 IPR004147 UbiB domain UA74_RS12910 3cb3ff66e82411ba610ead3b0756e6c3 661 SUPERFAMILY SSF56112 287 408 1.37E-25 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS12910 3cb3ff66e82411ba610ead3b0756e6c3 661 SUPERFAMILY SSF56112 189 252 1.37E-25 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS12910 3cb3ff66e82411ba610ead3b0756e6c3 661 Gene3D G3DSA:3.90.1200.10 360 410 1.3E-6 T 09-03-2017 UA74_RS23670 3255d9547f447c1126c9b1cbbb988aba 385 Gene3D G3DSA:3.20.20.70 120 331 9.9E-8 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS23670 3255d9547f447c1126c9b1cbbb988aba 385 Pfam PF06187 Protein of unknown function (DUF993) 3 383 4.2E-183 T 09-03-2017 IPR009334 Protein of unknown function DUF993 UA74_RS23670 3255d9547f447c1126c9b1cbbb988aba 385 SUPERFAMILY SSF51569 56 331 1.67E-14 T 09-03-2017 UA74_RS01025 5a3b6c61d61f36c75916a504d5d1dee6 336 SUPERFAMILY SSF161098 92 161 4.06E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01025 5a3b6c61d61f36c75916a504d5d1dee6 336 SUPERFAMILY SSF161098 198 319 4.06E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01025 5a3b6c61d61f36c75916a504d5d1dee6 336 Gene3D G3DSA:1.10.3720.10 91 164 1.0E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01025 5a3b6c61d61f36c75916a504d5d1dee6 336 Gene3D G3DSA:1.10.3720.10 201 329 1.0E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01025 5a3b6c61d61f36c75916a504d5d1dee6 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 334 4.9E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS15145 364cbb0d92336756f52ca39c2ba5d515 309 SUPERFAMILY SSF51735 112 246 5.29E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15145 364cbb0d92336756f52ca39c2ba5d515 309 SUPERFAMILY SSF50129 11 141 4.07E-20 T 09-03-2017 IPR011032 GroES-like UA74_RS15145 364cbb0d92336756f52ca39c2ba5d515 309 SMART SM00829 9 306 1.8E-7 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS15145 364cbb0d92336756f52ca39c2ba5d515 309 Pfam PF13602 Zinc-binding dehydrogenase 178 306 6.0E-10 T 09-03-2017 UA74_RS15145 364cbb0d92336756f52ca39c2ba5d515 309 Gene3D G3DSA:3.90.180.10 12 139 1.3E-23 T 09-03-2017 IPR011032 GroES-like UA74_RS15145 364cbb0d92336756f52ca39c2ba5d515 309 Gene3D G3DSA:3.40.50.720 140 227 5.6E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 SUPERFAMILY SSF50494 191 372 2.07E-33 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 Gene3D G3DSA:2.40.10.10 188 268 5.0E-16 T 09-03-2017 UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 Pfam PF02674 Colicin V production protein 4 146 3.3E-15 T 09-03-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 Pfam PF13365 Trypsin-like peptidase domain 217 353 4.1E-21 T 09-03-2017 UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 4.6E-7 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 225 237 4.6E-7 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 284 308 4.6E-7 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 4.6E-7 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS01250 03279be5d168d70f71c524fe2eba93f9 394 Gene3D G3DSA:2.40.10.10 279 373 8.7E-12 T 09-03-2017 UA74_RS23930 79aedaec899c5a09cc09c4a38f4be851 490 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 247 1.7E-28 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_RS23930 79aedaec899c5a09cc09c4a38f4be851 490 SUPERFAMILY SSF53067 6 249 1.49E-43 T 09-03-2017 UA74_RS23930 79aedaec899c5a09cc09c4a38f4be851 490 Gene3D G3DSA:3.30.420.40 5 246 5.6E-26 T 09-03-2017 UA74_RS23930 79aedaec899c5a09cc09c4a38f4be851 490 Gene3D G3DSA:3.30.420.40 365 476 1.1E-17 T 09-03-2017 UA74_RS23930 79aedaec899c5a09cc09c4a38f4be851 490 SUPERFAMILY SSF53067 255 475 1.84E-35 T 09-03-2017 UA74_RS23930 79aedaec899c5a09cc09c4a38f4be851 490 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 448 4.6E-37 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_RS17680 351f32961885ceeb438321d7c1008821 465 SUPERFAMILY SSF51905 8 198 3.53E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17680 351f32961885ceeb438321d7c1008821 465 SUPERFAMILY SSF51905 305 352 3.53E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17680 351f32961885ceeb438321d7c1008821 465 Pfam PF12831 FAD dependent oxidoreductase 10 179 3.5E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17680 351f32961885ceeb438321d7c1008821 465 Gene3D G3DSA:3.50.50.60 307 344 1.3E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17680 351f32961885ceeb438321d7c1008821 465 Gene3D G3DSA:3.50.50.60 10 195 1.3E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 1.9E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 1.9E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 1.9E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 SUPERFAMILY SSF46894 171 237 2.45E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 SMART SM00421 174 231 6.6E-24 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 SMART SM00448 31 143 2.6E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 Gene3D G3DSA:3.40.50.2300 32 148 2.0E-27 T 09-03-2017 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 Pfam PF00072 Response regulator receiver domain 33 136 3.6E-19 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 Gene3D G3DSA:1.10.10.10 149 237 5.2E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 2.5E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23820 0caf06f635f5b197d6bf56eaa432603d 238 SUPERFAMILY SSF52172 32 152 3.7E-25 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS10515 276958e68be858837a69246319e26fec 440 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 288 1.8E-31 T 09-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS10515 276958e68be858837a69246319e26fec 440 Gene3D G3DSA:3.40.50.720 227 434 7.3E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10515 276958e68be858837a69246319e26fec 440 SUPERFAMILY SSF51735 4 185 1.81E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10515 276958e68be858837a69246319e26fec 440 PIRSF PIRSF000124 3 433 3.1E-116 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_RS10515 276958e68be858837a69246319e26fec 440 SUPERFAMILY SSF48179 196 293 8.33E-28 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS10515 276958e68be858837a69246319e26fec 440 Gene3D G3DSA:3.40.50.720 4 190 8.4E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10515 276958e68be858837a69246319e26fec 440 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 418 1.8E-26 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS10515 276958e68be858837a69246319e26fec 440 SMART SM00984 316 418 8.4E-35 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS10515 276958e68be858837a69246319e26fec 440 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 414 6.0E-121 T 09-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_RS10515 276958e68be858837a69246319e26fec 440 SUPERFAMILY SSF52413 307 427 7.46E-30 T 09-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS10515 276958e68be858837a69246319e26fec 440 Gene3D G3DSA:1.20.5.100 196 226 3.4E-13 T 09-03-2017 UA74_RS10515 276958e68be858837a69246319e26fec 440 PIRSF PIRSF500134 3 435 7.9E-134 T 09-03-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 UA74_RS10515 276958e68be858837a69246319e26fec 440 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 174 4.6E-49 T 09-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF53706 254 719 6.18E-69 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 144 5.1E-16 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.40.50.740 593 714 2.2E-38 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.40.50.740 430 467 2.2E-38 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.40.50.740 320 391 2.2E-38 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 47 64 - T 09-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.10.20.30 9 91 2.5E-7 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF01568 Molydopterin dinucleotide binding domain 755 830 8.0E-8 T 09-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF54862 228 259 5.02E-28 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF54862 98 201 5.02E-28 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 SMART SM00926 263 317 1.4E-5 T 09-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 09-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 SMART SM00929 105 145 3.1E-19 T 09-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 96 6.3E-16 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:2.20.25.90 266 315 1.3E-9 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF00384 Molybdopterin oxidoreductase 548 684 1.9E-7 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF00384 Molybdopterin oxidoreductase 320 463 2.2E-10 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 09-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:2.40.40.20 752 831 3.5E-7 T 09-03-2017 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF54292 18 93 2.03E-17 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 UA74_RS02570 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF50692 749 829 3.25E-9 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain UA74_RS21165 99ee7a876bb26082f2030233186ec3df 265 Pfam PF09339 IclR helix-turn-helix domain 16 65 3.1E-13 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS21165 99ee7a876bb26082f2030233186ec3df 265 SUPERFAMILY SSF46785 16 87 1.36E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21165 99ee7a876bb26082f2030233186ec3df 265 Pfam PF01614 Bacterial transcriptional regulator 131 252 1.1E-28 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS21165 99ee7a876bb26082f2030233186ec3df 265 SMART SM00346 14 103 2.1E-20 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS21165 99ee7a876bb26082f2030233186ec3df 265 SUPERFAMILY SSF55781 85 258 3.73E-49 T 09-03-2017 IPR029016 GAF domain-like UA74_RS21165 99ee7a876bb26082f2030233186ec3df 265 Gene3D G3DSA:1.10.10.10 13 86 9.4E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21165 99ee7a876bb26082f2030233186ec3df 265 Gene3D G3DSA:3.30.450.40 87 259 2.1E-53 T 09-03-2017 IPR029016 GAF domain-like UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 SMART SM00342 24 107 2.0E-31 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 SUPERFAMILY SSF46689 60 112 4.48E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 Gene3D G3DSA:1.10.10.60 62 112 1.6E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 SUPERFAMILY SSF46689 8 58 1.03E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 Pfam PF12833 Helix-turn-helix domain 30 108 1.6E-24 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 Gene3D G3DSA:1.10.10.60 7 61 1.1E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 76 91 4.8E-5 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_RS06135 70f3a43413896f00d1f697381b3b1c39 134 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 91 107 4.8E-5 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_RS06050 8661893a494759e678deced9d335e7b1 333 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS06050 8661893a494759e678deced9d335e7b1 333 SMART SM00382 30 214 3.7E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS06050 8661893a494759e678deced9d335e7b1 333 Pfam PF00005 ABC transporter 22 164 7.0E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS06050 8661893a494759e678deced9d335e7b1 333 SUPERFAMILY SSF52540 6 228 3.97E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06050 8661893a494759e678deced9d335e7b1 333 Gene3D G3DSA:3.40.50.300 1 231 1.0E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18920 6c2127de04d2ff89980720593042f275 350 Gene3D G3DSA:1.10.260.40 17 69 1.1E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18920 6c2127de04d2ff89980720593042f275 350 Pfam PF13377 Periplasmic binding protein-like domain 182 343 4.3E-42 T 09-03-2017 UA74_RS18920 6c2127de04d2ff89980720593042f275 350 Gene3D G3DSA:3.40.50.2300 188 318 2.1E-54 T 09-03-2017 UA74_RS18920 6c2127de04d2ff89980720593042f275 350 SMART SM00354 17 84 3.6E-7 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS18920 6c2127de04d2ff89980720593042f275 350 Gene3D G3DSA:3.40.50.2300 71 187 2.5E-24 T 09-03-2017 UA74_RS18920 6c2127de04d2ff89980720593042f275 350 SUPERFAMILY SSF47413 17 68 6.33E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18920 6c2127de04d2ff89980720593042f275 350 SUPERFAMILY SSF53822 75 346 6.9E-77 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS18920 6c2127de04d2ff89980720593042f275 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 62 1.6E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 SUPERFAMILY SSF54826 3 136 1.68E-38 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 SUPERFAMILY SSF51604 182 428 5.63E-69 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 Pfam PF13378 Enolase C-terminal domain-like 203 414 2.1E-62 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 134 4.1E-8 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 Gene3D G3DSA:3.20.20.120 177 407 1.6E-84 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 SMART SM00922 197 293 4.7E-27 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 Gene3D G3DSA:3.30.390.10 2 176 9.4E-81 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS10250 10a8e37ce9fda5fb557c57c54503670c 432 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 243 274 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 Pfam PF13361 UvrD-like helicase C-terminal domain 670 753 1.3E-10 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 Pfam PF00580 UvrD/REP helicase N-terminal domain 261 538 2.4E-18 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 Gene3D G3DSA:3.40.50.300 470 561 1.4E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 Gene3D G3DSA:3.40.50.300 259 363 1.4E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 Gene3D G3DSA:3.40.50.300 562 760 5.9E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 SUPERFAMILY SSF52540 255 391 1.09E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 SUPERFAMILY SSF52540 444 755 1.09E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19195 68baae3850ba5fc0eae1de988adb40ca 762 SUPERFAMILY SSF143011 1 88 1.41E-5 T 09-03-2017 UA74_RS08770 eba419bee012936079c593871b5d1570 519 Pfam PF07995 Glucose / Sorbosone dehydrogenase 64 347 1.6E-46 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 UA74_RS08770 eba419bee012936079c593871b5d1570 519 SMART SM00637 418 518 4.0E-40 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS08770 eba419bee012936079c593871b5d1570 519 SUPERFAMILY SSF49384 413 518 1.26E-32 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS08770 eba419bee012936079c593871b5d1570 519 Pfam PF00553 Cellulose binding domain 418 518 1.1E-29 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS08770 eba419bee012936079c593871b5d1570 519 SUPERFAMILY SSF50952 56 324 3.92E-29 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS08770 eba419bee012936079c593871b5d1570 519 SUPERFAMILY SSF50952 360 429 3.92E-29 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS08770 eba419bee012936079c593871b5d1570 519 Gene3D G3DSA:2.120.10.30 52 408 2.1E-93 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS08770 eba419bee012936079c593871b5d1570 519 Gene3D G3DSA:2.60.40.290 417 518 1.3E-34 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS09005 f7c938048fffc4903df7b9812ce43e20 128 SUPERFAMILY SSF52980 20 115 2.41E-19 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS09005 f7c938048fffc4903df7b9812ce43e20 128 Gene3D G3DSA:3.40.1350.10 20 127 6.4E-33 T 09-03-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 UA74_RS09005 f7c938048fffc4903df7b9812ce43e20 128 Hamap MF_00048 UPF0102 protein YraN [yraN]. 14 124 20.741 T 09-03-2017 IPR003509 Uncharacterised protein family UPF0102 UA74_RS09005 f7c938048fffc4903df7b9812ce43e20 128 Pfam PF02021 Uncharacterised protein family UPF0102 21 111 8.8E-27 T 09-03-2017 IPR003509 Uncharacterised protein family UPF0102 UA74_RS26945 f7ddcb491c5997951f30b6648857f02a 330 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 307 4.5E-38 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS05395 b177f76ab84a5b37f7b25099492763d9 397 SUPERFAMILY SSF55874 273 384 7.26E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05395 b177f76ab84a5b37f7b25099492763d9 397 Gene3D G3DSA:3.30.565.10 272 392 8.7E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05395 b177f76ab84a5b37f7b25099492763d9 397 Pfam PF07730 Histidine kinase 187 251 3.2E-15 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS17865 0929005503b4c7c15d0df6bf2c159da2 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 1.6E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS17865 0929005503b4c7c15d0df6bf2c159da2 202 SUPERFAMILY SSF46689 14 90 2.54E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17865 0929005503b4c7c15d0df6bf2c159da2 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 7.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS17865 0929005503b4c7c15d0df6bf2c159da2 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 7.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS17865 0929005503b4c7c15d0df6bf2c159da2 202 SUPERFAMILY SSF48498 92 199 7.71E-13 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS17865 0929005503b4c7c15d0df6bf2c159da2 202 Gene3D G3DSA:1.10.357.10 15 201 6.6E-43 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS17865 0929005503b4c7c15d0df6bf2c159da2 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 69 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS26935 73c28437f71604cf8f7bed1d53987d3e 361 Gene3D G3DSA:3.40.50.2300 58 180 3.6E-25 T 09-03-2017 UA74_RS26935 73c28437f71604cf8f7bed1d53987d3e 361 Gene3D G3DSA:3.40.50.2300 181 310 1.8E-29 T 09-03-2017 UA74_RS26935 73c28437f71604cf8f7bed1d53987d3e 361 SUPERFAMILY SSF53822 60 361 2.57E-64 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS26935 73c28437f71604cf8f7bed1d53987d3e 361 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 62 361 4.1E-114 T 09-03-2017 IPR013459 Rhamnose-binding protein GO:0015762 UA74_RS26935 73c28437f71604cf8f7bed1d53987d3e 361 Pfam PF13407 Periplasmic binding protein domain 62 318 7.6E-54 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 17 501 81.996 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 SUPERFAMILY SSF51412 225 492 2.35E-113 T 09-03-2017 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 SUPERFAMILY SSF51412 12 99 2.35E-113 T 09-03-2017 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 PIRSF PIRSF000130 9 502 3.6E-197 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 Gene3D G3DSA:3.20.20.70 13 500 1.3E-187 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 304 316 - T 09-03-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 SMART SM01240 16 488 2.6E-301 T 09-03-2017 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 SMART SM00116 166 214 2.4E-7 T 09-03-2017 IPR000644 CBS domain UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 SMART SM00116 105 153 6.4E-7 T 09-03-2017 IPR000644 CBS domain UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 17 488 1.4E-152 T 09-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 SUPERFAMILY SSF54631 102 211 1.52E-28 T 09-03-2017 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 17 470 3.4E-179 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 Pfam PF00571 CBS domain 102 149 4.2E-8 T 09-03-2017 IPR000644 CBS domain UA74_RS28060 07215f563d68aa8f1bfdd2527968e1da 502 Pfam PF00571 CBS domain 158 211 1.2E-6 T 09-03-2017 IPR000644 CBS domain UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 32 50 2.4E-23 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 282 296 2.4E-23 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 119 137 2.4E-23 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 99 110 2.4E-23 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 128 139 - T 09-03-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 Gene3D G3DSA:3.30.70.890 227 397 1.2E-49 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 Gene3D G3DSA:3.30.230.10 10 226 1.4E-64 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 SUPERFAMILY SSF55060 223 397 3.96E-43 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 ProSitePatterns PS00106 Galactokinase signature. 32 43 - T 09-03-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 Pfam PF00288 GHMP kinases N terminal domain 122 196 6.7E-14 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PIRSF PIRSF000530 1 400 2.7E-110 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 178 197 4.6E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 126 148 4.6E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 30 54 4.6E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 345 362 4.6E-40 T 09-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 Pfam PF10509 Galactokinase galactose-binding signature 15 62 1.8E-20 T 09-03-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 Pfam PF08544 GHMP kinases C terminal 303 377 9.9E-13 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 SUPERFAMILY SSF54211 7 218 1.29E-54 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS08825 366bd2d755c87eb5f255c7785b29a837 404 TIGRFAM TIGR00131 gal_kin: galactokinase 11 388 2.9E-79 T 09-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 384 393 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 Gene3D G3DSA:1.10.630.10 19 444 1.3E-83 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 267 284 1.2E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 382 391 1.2E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 310 321 1.2E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 391 402 1.2E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 45 64 1.7E-24 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 391 414 1.7E-24 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 309 327 1.7E-24 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 349 373 1.7E-24 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 381 391 1.7E-24 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 256 273 1.7E-24 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 276 302 1.7E-24 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 Pfam PF00067 Cytochrome P450 19 428 1.2E-51 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12805 e75d78344f054db3a974c5bb1d8afa2d 444 SUPERFAMILY SSF48264 18 444 2.36E-81 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 SUPERFAMILY SSF81296 5 147 2.8E-44 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 SUPERFAMILY SSF51445 500 576 3.58E-135 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 SUPERFAMILY SSF51445 133 471 3.58E-135 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 6.3E-18 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 SUPERFAMILY SSF51011 590 716 1.58E-23 T 09-03-2017 UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 680 0.0 T 09-03-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 Gene3D G3DSA:3.20.20.80 152 577 1.8E-123 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 Pfam PF00128 Alpha amylase, catalytic domain 188 529 2.4E-10 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 Gene3D G3DSA:2.60.40.1180 589 717 7.4E-31 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 SMART SM00642 158 568 1.1E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS21300 588fa91430324ca51a2afdd22e6b7300 722 Gene3D G3DSA:2.60.40.10 5 151 2.2E-57 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS03785 f5e3ac92dd0165551cdb61fa9c6b119a 219 Pfam PF13559 Domain of unknown function (DUF4129) 128 197 1.8E-5 T 09-03-2017 IPR025403 Domain of unknown function DUF4129 UA74_RS10995 d25b629deafac0a4d252785f3fa076c0 335 Gene3D G3DSA:3.40.50.150 101 319 1.1E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10995 d25b629deafac0a4d252785f3fa076c0 335 SUPERFAMILY SSF46785 14 83 4.52E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10995 d25b629deafac0a4d252785f3fa076c0 335 Pfam PF00891 O-methyltransferase 103 318 1.9E-39 T 09-03-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_RS10995 d25b629deafac0a4d252785f3fa076c0 335 Gene3D G3DSA:1.10.10.10 8 86 9.9E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10995 d25b629deafac0a4d252785f3fa076c0 335 Pfam PF16864 Dimerisation domain 14 93 5.5E-14 T 09-03-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_RS10995 d25b629deafac0a4d252785f3fa076c0 335 SUPERFAMILY SSF53335 97 331 9.4E-43 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10995 d25b629deafac0a4d252785f3fa076c0 335 PIRSF PIRSF005739 2 333 1.3E-28 T 09-03-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_RS17985 181688964cf4c8e1fdf6e0e8d169ece5 429 Pfam PF04143 Sulphur transport 81 409 1.0E-62 T 09-03-2017 IPR007272 Sulphur transport domain UA74_RS06895 4618e078684b2d81a4fdcada01ebcd2e 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 58 2.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06895 4618e078684b2d81a4fdcada01ebcd2e 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS06895 4618e078684b2d81a4fdcada01ebcd2e 196 Gene3D G3DSA:1.10.357.10 72 192 3.4E-21 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06895 4618e078684b2d81a4fdcada01ebcd2e 196 Pfam PF16925 Bacterial transcriptional repressor C-terminal 98 191 2.6E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS06895 4618e078684b2d81a4fdcada01ebcd2e 196 SUPERFAMILY SSF46689 2 82 9.23E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06895 4618e078684b2d81a4fdcada01ebcd2e 196 SUPERFAMILY SSF48498 79 192 3.67E-23 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS06895 4618e078684b2d81a4fdcada01ebcd2e 196 Gene3D G3DSA:1.10.10.60 1 64 1.9E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 2 393 2.0E-131 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 86 291 3.5E-25 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 Pfam PF03129 Anticodon binding domain 305 392 2.2E-9 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 SUPERFAMILY SSF55681 3 290 8.48E-84 T 09-03-2017 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 Gene3D G3DSA:3.30.930.10 3 293 2.6E-94 T 09-03-2017 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 SUPERFAMILY SSF52954 293 406 1.34E-18 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 124 147 5.0E-43 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 228 256 5.0E-43 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 271 284 5.0E-43 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 298 310 5.0E-43 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 91 119 5.0E-43 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS19670 02ef8dde54e6f4b59a8faea159a07d60 409 Gene3D G3DSA:3.40.50.800 295 403 1.0E-19 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 Gene3D G3DSA:1.10.10.10 125 204 1.2E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 126 204 2.6E-27 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 45 120 5.7E-7 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 Gene3D G3DSA:3.30.160.70 41 120 1.4E-8 T 09-03-2017 UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 SUPERFAMILY SSF46767 124 203 2.22E-26 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 126 203 2.8E-29 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 174 180 - T 09-03-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_RS28890 71b84f7885fa91e05af169fa0cd5c9df 205 SUPERFAMILY SSF53155 43 120 4.12E-17 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_RS18330 d7708e48f15080a4092d87cae7679c35 282 Pfam PF13560 Helix-turn-helix domain 11 70 2.9E-9 T 09-03-2017 UA74_RS18330 d7708e48f15080a4092d87cae7679c35 282 SUPERFAMILY SSF47413 9 66 9.38E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18330 d7708e48f15080a4092d87cae7679c35 282 Gene3D G3DSA:1.10.260.40 6 66 1.4E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18330 d7708e48f15080a4092d87cae7679c35 282 SMART SM00530 15 70 0.0016 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 55 190 1.8E-40 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF53738 45 197 3.06E-42 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF53738 353 496 1.81E-24 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF53738 276 360 8.24E-19 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 150 159 - T 09-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 275 360 4.4E-21 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 534 571 7.2E-7 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Gene3D G3DSA:3.40.120.10 40 215 1.6E-54 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Gene3D G3DSA:3.40.120.10 279 356 1.4E-18 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 374 491 1.3E-16 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Gene3D G3DSA:3.30.310.50 521 572 1.7E-11 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 149 163 5.9E-6 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 345 360 5.9E-6 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF55957 488 571 5.76E-9 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27425 69c5de80d6df02338de906a5331f88c0 631 Gene3D G3DSA:3.40.120.10 357 499 1.3E-30 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 337 358 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 Gene3D G3DSA:3.30.420.40 2 234 3.1E-49 T 09-03-2017 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 PIRSF PIRSF000538 1 465 2.0E-84 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 243 425 3.5E-27 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 SUPERFAMILY SSF53067 4 236 2.47E-51 T 09-03-2017 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 Gene3D G3DSA:3.30.420.40 238 427 1.2E-29 T 09-03-2017 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 PRINTS PR00301 70kDa heat shock protein signature 3 16 4.0E-5 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 PRINTS PR00301 70kDa heat shock protein signature 408 428 4.0E-5 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 PRINTS PR00301 70kDa heat shock protein signature 378 394 4.0E-5 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 SUPERFAMILY SSF53067 237 428 2.86E-41 T 09-03-2017 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 214 7.0E-48 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_RS27355 f5f028be3153445f4968f157a97ed759 479 TIGRFAM TIGR01312 XylB: xylulokinase 5 428 2.8E-123 T 09-03-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 Gene3D G3DSA:3.50.50.60 1 107 4.3E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 Gene3D G3DSA:3.50.50.60 108 306 4.5E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 3.6E-10 T 09-03-2017 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.6E-10 T 09-03-2017 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.6E-10 T 09-03-2017 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.6E-10 T 09-03-2017 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 SUPERFAMILY SSF51905 2 302 6.74E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 294 2.6E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS08200 202fa4c1829d326467faebc9d16516c4 292 PIRSF PIRSF015626 1 276 2.1E-87 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 UA74_RS08200 202fa4c1829d326467faebc9d16516c4 292 SUPERFAMILY SSF53927 4 272 1.02E-78 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 UA74_RS08200 202fa4c1829d326467faebc9d16516c4 292 Gene3D G3DSA:3.10.20.10 28 120 2.4E-26 T 09-03-2017 UA74_RS08200 202fa4c1829d326467faebc9d16516c4 292 Gene3D G3DSA:3.40.140.10 136 275 2.4E-56 T 09-03-2017 UA74_RS08200 202fa4c1829d326467faebc9d16516c4 292 Pfam PF02634 FdhD/NarQ family 26 272 2.1E-83 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 UA74_RS08200 202fa4c1829d326467faebc9d16516c4 292 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 8.3E-52 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 UA74_RS08200 202fa4c1829d326467faebc9d16516c4 292 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 273 34.679 T 09-03-2017 IPR003786 Protein FdhD GO:0016783 UA74_RS26585 0688ff579d715e5e9688c46e3419e41e 81 Gene3D G3DSA:3.30.450.20 16 80 3.5E-7 T 09-03-2017 UA74_RS26585 0688ff579d715e5e9688c46e3419e41e 81 SUPERFAMILY SSF55785 21 81 1.54E-6 T 09-03-2017 IPR000014 PAS domain UA74_RS26585 0688ff579d715e5e9688c46e3419e41e 81 Pfam PF08447 PAS fold 6 81 1.1E-7 T 09-03-2017 IPR013655 PAS fold-3 GO:0005515 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 Gene3D G3DSA:2.40.30.10 136 231 8.5E-22 T 09-03-2017 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 SUPERFAMILY SSF52343 235 364 1.83E-28 T 09-03-2017 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 PRINTS PR00410 Phenol hydroxylase reductase family signature 331 339 1.4E-13 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 PRINTS PR00410 Phenol hydroxylase reductase family signature 242 261 1.4E-13 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 PRINTS PR00410 Phenol hydroxylase reductase family signature 164 176 1.4E-13 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 PRINTS PR00410 Phenol hydroxylase reductase family signature 267 276 1.4E-13 T 09-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 Pfam PF00970 Oxidoreductase FAD-binding domain 139 231 4.6E-15 T 09-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 Gene3D G3DSA:1.10.490.10 2 131 1.6E-37 T 09-03-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 SUPERFAMILY SSF63380 136 231 2.15E-22 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 Pfam PF00042 Globin 2 94 1.5E-9 T 09-03-2017 IPR000971 Globin GO:0019825|GO:0020037 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 Gene3D G3DSA:3.40.50.80 235 364 1.2E-30 T 09-03-2017 UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 SUPERFAMILY SSF46458 2 127 1.38E-32 T 09-03-2017 IPR009050 Globin-like UA74_RS29750 10815ac8f5c1f1973ae3f80551bc6fbf 366 Pfam PF00175 Oxidoreductase NAD-binding domain 243 344 1.8E-14 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 SUPERFAMILY SSF56176 354 450 7.91E-13 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 Pfam PF03471 Transporter associated domain 357 447 3.5E-12 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 SUPERFAMILY SSF54631 222 349 2.02E-24 T 09-03-2017 UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 Gene3D G3DSA:3.30.465.10 333 444 1.2E-15 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 Gene3D G3DSA:3.10.580.10 210 332 6.0E-18 T 09-03-2017 UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 SMART SM01091 354 448 4.7E-10 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 Pfam PF00571 CBS domain 228 276 1.9E-5 T 09-03-2017 IPR000644 CBS domain UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 Pfam PF00571 CBS domain 284 338 0.0048 T 09-03-2017 IPR000644 CBS domain UA74_RS05290 54cf447e12f87cba3284378421dfed6c 466 Pfam PF01595 Domain of unknown function DUF21 13 206 3.4E-35 T 09-03-2017 IPR002550 Domain of unknown function DUF21 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 Pfam PF01297 Zinc-uptake complex component A periplasmic 58 329 3.2E-57 T 09-03-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 Gene3D G3DSA:3.40.50.1980 207 332 1.7E-36 T 09-03-2017 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 Gene3D G3DSA:3.40.50.1980 50 206 1.2E-34 T 09-03-2017 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 55 73 1.7E-32 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 99 116 1.7E-32 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 267 285 1.7E-32 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 298 317 1.7E-32 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 86 99 1.7E-32 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 214 235 1.7E-32 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 SUPERFAMILY SSF53807 52 332 4.17E-61 T 09-03-2017 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 99 118 9.8E-18 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 55 76 9.8E-18 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 156 175 9.8E-18 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 263 280 9.8E-18 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 80 98 9.8E-18 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS11355 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 214 231 9.8E-18 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS06195 c4f7ad7b1cbbdec7715e0bc41462f312 150 Gene3D G3DSA:3.10.450.50 9 132 9.8E-18 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS06195 c4f7ad7b1cbbdec7715e0bc41462f312 150 Pfam PF12680 SnoaL-like domain 10 119 1.2E-15 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS06195 c4f7ad7b1cbbdec7715e0bc41462f312 150 SUPERFAMILY SSF54427 9 132 6.53E-21 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS03585 61f5ded7214b285f4405797d8710c5d1 452 SUPERFAMILY SSF103473 61 447 7.32E-24 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS03585 61f5ded7214b285f4405797d8710c5d1 452 Gene3D G3DSA:1.20.1250.20 262 445 4.8E-6 T 09-03-2017 UA74_RS03585 61f5ded7214b285f4405797d8710c5d1 452 Pfam PF07690 Major Facilitator Superfamily 67 401 3.0E-14 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS03585 61f5ded7214b285f4405797d8710c5d1 452 Gene3D G3DSA:1.20.1250.20 66 237 7.0E-10 T 09-03-2017 UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 Gene3D G3DSA:3.90.1150.10 338 427 2.6E-46 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 Gene3D G3DSA:3.90.1150.10 5 66 2.6E-46 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 SUPERFAMILY SSF53383 6 427 2.23E-115 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 14 426 1.0E-162 T 09-03-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 Gene3D G3DSA:3.40.640.10 67 333 1.1E-82 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 2 430 47.557 T 09-03-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 UA74_RS09880 b7cd0aac33fbb62e890809ddd0fa025d 430 Pfam PF00202 Aminotransferase class-III 28 426 3.8E-110 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS02465 a4664bf752f5aff882c9ab461c622c02 398 SUPERFAMILY SSF56801 31 389 9.03E-76 T 09-03-2017 UA74_RS02465 a4664bf752f5aff882c9ab461c622c02 398 Pfam PF00501 AMP-binding enzyme 46 291 5.2E-37 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS02465 a4664bf752f5aff882c9ab461c622c02 398 Pfam PF13193 AMP-binding enzyme C-terminal domain 301 376 2.6E-14 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS02465 a4664bf752f5aff882c9ab461c622c02 398 ProSitePatterns PS00455 Putative AMP-binding domain signature. 61 72 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS02465 a4664bf752f5aff882c9ab461c622c02 398 Gene3D G3DSA:3.30.300.30 286 385 6.9E-22 T 09-03-2017 UA74_RS02465 a4664bf752f5aff882c9ab461c622c02 398 Gene3D G3DSA:2.30.38.10 228 285 1.5E-12 T 09-03-2017 UA74_RS02465 a4664bf752f5aff882c9ab461c622c02 398 Gene3D G3DSA:3.40.50.980 56 218 6.8E-24 T 09-03-2017 UA74_RS26525 4c7e1328a546b3df049390c9f340d6ac 510 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 7 506 3.0E-193 T 09-03-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_RS26525 4c7e1328a546b3df049390c9f340d6ac 510 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 09-03-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 UA74_RS26525 4c7e1328a546b3df049390c9f340d6ac 510 SUPERFAMILY SSF48557 2 503 2.35E-176 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 UA74_RS26525 4c7e1328a546b3df049390c9f340d6ac 510 Gene3D G3DSA:1.20.200.10 200 508 4.2E-114 T 09-03-2017 UA74_RS26525 4c7e1328a546b3df049390c9f340d6ac 510 Gene3D G3DSA:1.10.275.10 3 199 3.4E-69 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal UA74_RS26525 4c7e1328a546b3df049390c9f340d6ac 510 Pfam PF00221 Aromatic amino acid lyase 12 473 1.2E-176 T 09-03-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 Pfam PF08281 Sigma-70, region 4 105 157 9.5E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 Gene3D G3DSA:1.10.10.10 102 163 5.7E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 SUPERFAMILY SSF88659 81 163 3.92E-13 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 SUPERFAMILY SSF88946 4 92 4.71E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 3.2E-22 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 161 2.1E-48 T 09-03-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 Pfam PF04542 Sigma-70 region 2 17 79 1.7E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29505 e4c70fce2d93d789f1fd04a3f051aa2e 172 Gene3D G3DSA:1.10.1740.10 3 81 4.9E-16 T 09-03-2017 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.1E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.1E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 161 214 2.5E-11 T 09-03-2017 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 Gene3D G3DSA:1.10.357.10 66 219 2.6E-36 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 SUPERFAMILY SSF46689 16 91 2.77E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 Gene3D G3DSA:1.10.10.60 16 65 8.7E-21 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.1E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06515 e50e196f47f51eab0116cb9fc69bb268 222 SUPERFAMILY SSF48498 101 212 3.26E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS19650 9b3e5e82331fac0ee0a94f9b5509b152 386 SUPERFAMILY SSF51604 144 383 1.18E-60 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS19650 9b3e5e82331fac0ee0a94f9b5509b152 386 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 50 144 4.9E-12 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS19650 9b3e5e82331fac0ee0a94f9b5509b152 386 Gene3D G3DSA:3.20.20.120 151 381 1.5E-65 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS19650 9b3e5e82331fac0ee0a94f9b5509b152 386 SMART SM00922 163 258 2.0E-15 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS19650 9b3e5e82331fac0ee0a94f9b5509b152 386 SUPERFAMILY SSF54826 1 149 4.57E-21 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS19650 9b3e5e82331fac0ee0a94f9b5509b152 386 Gene3D G3DSA:3.30.390.10 1 150 6.2E-37 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS19650 9b3e5e82331fac0ee0a94f9b5509b152 386 Pfam PF13378 Enolase C-terminal domain-like 167 378 1.6E-53 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS20530 2f0270092656353ac641d8babed64d53 211 Gene3D G3DSA:3.40.50.720 4 192 1.5E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20530 2f0270092656353ac641d8babed64d53 211 SUPERFAMILY SSF51735 4 193 3.19E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20530 2f0270092656353ac641d8babed64d53 211 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 90 1.6E-17 T 09-03-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_RS11905 9077d6ec928a576ea74b4cd7c6ff8187 90 Gene3D G3DSA:1.10.260.40 10 74 2.3E-24 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS11905 9077d6ec928a576ea74b4cd7c6ff8187 90 SUPERFAMILY SSF47413 13 74 2.25E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS11905 9077d6ec928a576ea74b4cd7c6ff8187 90 Pfam PF13560 Helix-turn-helix domain 16 75 2.5E-10 T 09-03-2017 UA74_RS11905 9077d6ec928a576ea74b4cd7c6ff8187 90 SMART SM00530 20 74 2.3E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 Gene3D G3DSA:3.20.20.140 76 86 1.1E-33 T 09-03-2017 UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 Gene3D G3DSA:3.20.20.140 192 464 1.1E-33 T 09-03-2017 UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 SUPERFAMILY SSF51338 5 65 5.89E-9 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 SUPERFAMILY SSF51338 471 490 5.89E-9 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 SUPERFAMILY SSF51556 64 124 2.96E-32 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 SUPERFAMILY SSF51556 190 467 2.96E-32 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 Pfam PF07969 Amidohydrolase family 54 534 9.4E-82 T 09-03-2017 IPR013108 Amidohydrolase 3 UA74_RS13100 372d17fe082b6d46bc92c5bff4424ec3 544 Gene3D G3DSA:2.30.40.10 8 75 8.4E-10 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 SUPERFAMILY SSF55261 290 412 1.18E-33 T 09-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 579 4.7E-207 T 09-03-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Pfam PF02938 GAD domain 313 394 2.4E-13 T 09-03-2017 IPR029351 GAD domain Reactome: R-HSA-379726 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 5.9E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 5.9E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 5.9E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 5.9E-26 T 09-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 557 2.1E-99 T 09-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 SUPERFAMILY SSF55681 417 583 8.71E-98 T 09-03-2017 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 SUPERFAMILY SSF55681 115 293 8.71E-98 T 09-03-2017 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 7.6E-16 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 SUPERFAMILY SSF50249 2 104 1.14E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 563 35.332 T 09-03-2017 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Gene3D G3DSA:2.40.50.140 3 105 1.1E-35 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Gene3D G3DSA:3.30.930.10 407 582 1.1E-106 T 09-03-2017 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Gene3D G3DSA:3.30.930.10 136 277 1.1E-106 T 09-03-2017 UA74_RS12075 eead80e000d136a3e2752a4b9dbe802e 590 Gene3D G3DSA:3.30.1360.30 278 406 1.8E-40 T 09-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 SUPERFAMILY SSF50891 14 179 9.06E-61 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 16 178 3.1E-44 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 69 81 3.6E-25 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 124 136 3.6E-25 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 137 152 3.6E-25 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 28 43 3.6E-25 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 109 124 3.6E-25 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 Gene3D G3DSA:2.40.100.10 13 179 6.1E-62 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 PIRSF PIRSF001467 5 183 5.8E-56 T 09-03-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 UA74_RS00085 02b668c73dae4117052324f2bbc12322 184 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 64 81 - T 09-03-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 SUPERFAMILY SSF53098 2 157 4.55E-44 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 Gene3D G3DSA:3.30.420.10 1 157 3.4E-55 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 09-03-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 5.8E-55 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 9.3E-38 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 9.3E-38 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 9.3E-38 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 9.3E-38 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 9.3E-38 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 5.2E-34 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS11150 2c0be03a914750f5899fb8f62da1ae49 182 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 44.964 T 09-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_RS18515 bebaccb033142cb26ddcee37496eb21c 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 2.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS18515 bebaccb033142cb26ddcee37496eb21c 187 SUPERFAMILY SSF48498 80 185 6.37E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS18515 bebaccb033142cb26ddcee37496eb21c 187 Gene3D G3DSA:1.10.357.10 4 186 3.4E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS18515 bebaccb033142cb26ddcee37496eb21c 187 SUPERFAMILY SSF46689 3 80 5.49E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 Pfam PF00664 ABC transporter transmembrane region 17 287 2.2E-41 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 Gene3D G3DSA:3.40.50.300 332 563 3.2E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 SMART SM00382 359 551 5.9E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 Pfam PF00005 ABC transporter 350 497 2.3E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 SUPERFAMILY SSF52540 328 569 8.57E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 SUPERFAMILY SSF90123 5 312 9.81E-69 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS10440 c9fae5c5a2354e91c03890dd1f82313e 576 Gene3D G3DSA:1.20.1560.10 3 313 2.1E-60 T 09-03-2017 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 Pfam PF00072 Response regulator receiver domain 5 115 3.2E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 SUPERFAMILY SSF46894 133 205 1.16E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 SUPERFAMILY SSF52172 3 132 5.55E-32 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 SMART SM00448 2 115 5.8E-29 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 8.6E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 SMART SM00421 142 199 2.6E-21 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 Gene3D G3DSA:1.10.10.10 123 205 1.2E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 9.7E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 9.7E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 9.7E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24380 d6bb24d3bba0f4d922757d9d7ab45228 211 Gene3D G3DSA:3.40.50.2300 2 122 3.9E-34 T 09-03-2017 UA74_RS19290 d3a09fd77080ae177c87c192a3e7e361 222 Pfam PF02254 TrkA-N domain 12 126 1.2E-23 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_RS19290 d3a09fd77080ae177c87c192a3e7e361 222 SUPERFAMILY SSF116726 136 221 2.09E-17 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS19290 d3a09fd77080ae177c87c192a3e7e361 222 Gene3D G3DSA:3.40.50.720 7 141 1.1E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19290 d3a09fd77080ae177c87c192a3e7e361 222 SUPERFAMILY SSF51735 9 139 2.03E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19290 d3a09fd77080ae177c87c192a3e7e361 222 Gene3D G3DSA:3.30.70.1450 155 221 8.9E-16 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS19290 d3a09fd77080ae177c87c192a3e7e361 222 Pfam PF02080 TrkA-C domain 155 221 6.4E-12 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 Gene3D G3DSA:3.40.50.150 169 379 2.2E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 205 1.6E-15 T 09-03-2017 UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 213 227 1.6E-15 T 09-03-2017 UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 291 303 1.6E-15 T 09-03-2017 UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 SUPERFAMILY SSF53335 84 518 3.35E-116 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 SUPERFAMILY SSF53335 6 45 3.35E-116 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 294 300 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 Pfam PF02384 N-6 DNA Methylase 165 484 2.8E-94 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_RS16020 5f925c9aef79f31919065c05f0b8bb52 523 Pfam PF12161 HsdM N-terminal domain 8 151 2.9E-16 T 09-03-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain UA74_RS16525 a274bc0b327ae15a9891c90c6fa13689 25 SUPERFAMILY SSF101173 1 25 3.53E-6 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS16525 a274bc0b327ae15a9891c90c6fa13689 25 Pfam PF08990 Erythronolide synthase docking 3 25 1.8E-13 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 Gene3D G3DSA:1.10.630.10 8 374 2.3E-107 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 Pfam PF00067 Cytochrome P450 44 367 4.0E-23 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 189 211 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 82 93 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 145 160 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 128 144 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 336 345 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 315 330 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 270 281 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 287 314 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 345 356 7.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS10920 1692231d7419c9c9c5a35053a64ca88d 397 SUPERFAMILY SSF48264 21 390 2.75E-83 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 Pfam PF13404 AsnC-type helix-turn-helix domain 1 41 1.5E-15 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 SMART SM00344 1 108 4.5E-30 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 Gene3D G3DSA:1.10.10.10 2 53 2.1E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 09-03-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.0E-10 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.0E-10 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.0E-10 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 SUPERFAMILY SSF46785 1 61 4.08E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 Pfam PF01037 Lrp/AsnC ligand binding domain 85 137 4.3E-10 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 Gene3D G3DSA:3.30.70.920 54 146 1.9E-16 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS02640 612d6525159090802287f0419ed8ff0e 160 SUPERFAMILY SSF54909 64 146 7.78E-12 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS08925 64118c4d0d27c58d58878912e7c85d28 150 Pfam PF00886 Ribosomal protein S16 9 67 1.5E-22 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08925 64118c4d0d27c58d58878912e7c85d28 150 SUPERFAMILY SSF54565 2 90 1.96E-31 T 09-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08925 64118c4d0d27c58d58878912e7c85d28 150 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.0E-29 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08925 64118c4d0d27c58d58878912e7c85d28 150 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.36 T 09-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08925 64118c4d0d27c58d58878912e7c85d28 150 Gene3D G3DSA:3.30.1320.10 2 83 1.7E-30 T 09-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS10340 9dfa7224d186ff412f77118283a7b246 418 Pfam PF04542 Sigma-70 region 2 21 80 9.8E-11 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10340 9dfa7224d186ff412f77118283a7b246 418 Pfam PF08281 Sigma-70, region 4 121 171 9.6E-10 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10340 9dfa7224d186ff412f77118283a7b246 418 SUPERFAMILY SSF88659 111 172 2.06E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10340 9dfa7224d186ff412f77118283a7b246 418 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 172 2.0E-14 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10340 9dfa7224d186ff412f77118283a7b246 418 SUPERFAMILY SSF88946 5 87 3.26E-12 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10340 9dfa7224d186ff412f77118283a7b246 418 Gene3D G3DSA:1.10.10.10 113 172 3.0E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10340 9dfa7224d186ff412f77118283a7b246 418 Gene3D G3DSA:1.10.1740.10 5 80 2.3E-10 T 09-03-2017 UA74_RS08900 3ead08cb57f15ab1074ad29709fc7f85 1061 Pfam PF13569 Domain of unknown function (DUF4132) 816 949 7.3E-31 T 09-03-2017 IPR025406 Domain of unknown function DUF4132 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 Gene3D G3DSA:1.10.630.10 4 393 4.1E-122 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 Pfam PF00067 Cytochrome P450 193 363 1.2E-19 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 SUPERFAMILY SSF48264 8 393 5.24E-96 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 150 165 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 342 353 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 87 98 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 186 208 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 284 311 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 266 277 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 133 149 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 333 342 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS19745 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 312 327 9.9E-54 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 Gene3D G3DSA:3.40.50.200 218 502 4.2E-85 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 SUPERFAMILY SSF52743 218 503 5.11E-81 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 Pfam PF00082 Subtilase family 236 484 4.7E-60 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 Gene3D G3DSA:2.60.40.360 504 600 2.0E-9 T 09-03-2017 IPR008962 PapD-like UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 446 456 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 277 287 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 PRINTS PR00723 Subtilisin serine protease family (S8) signature 273 286 1.1E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 PRINTS PR00723 Subtilisin serine protease family (S8) signature 445 461 1.1E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 PRINTS PR00723 Subtilisin serine protease family (S8) signature 236 255 1.1E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS24030 2931b36441b0734ee4010f0a9117ee61 1124 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 241 252 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_RS05895 507946ba6de6b60d5ba98631b19cba03 225 SUPERFAMILY SSF53335 23 143 5.93E-13 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05895 507946ba6de6b60d5ba98631b19cba03 225 Pfam PF13649 Methyltransferase domain 28 102 2.2E-6 T 09-03-2017 UA74_RS05895 507946ba6de6b60d5ba98631b19cba03 225 Gene3D G3DSA:3.40.50.150 20 137 3.9E-9 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS27200 9713f08653c8897acff0e86a61386a4c 292 Pfam PF13560 Helix-turn-helix domain 14 75 3.1E-12 T 09-03-2017 UA74_RS27200 9713f08653c8897acff0e86a61386a4c 292 SUPERFAMILY SSF47413 11 70 2.76E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS27200 9713f08653c8897acff0e86a61386a4c 292 SMART SM00530 18 72 4.0E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS27200 9713f08653c8897acff0e86a61386a4c 292 Gene3D G3DSA:1.10.260.40 7 72 3.2E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS07215 7d46095d551946dd117dad4972eaab04 305 SUPERFAMILY SSF53850 55 282 1.9E-35 T 09-03-2017 UA74_RS07215 7d46095d551946dd117dad4972eaab04 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 55 280 2.3E-33 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS07215 7d46095d551946dd117dad4972eaab04 305 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 42 300 3.3E-68 T 09-03-2017 IPR014337 Ectoine/Hydroxyectoine-binding protein EhuB GO:0005886|GO:0033294|GO:0051470|GO:0051471 UA74_RS07215 7d46095d551946dd117dad4972eaab04 305 SMART SM00062 54 288 1.4E-27 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS07215 7d46095d551946dd117dad4972eaab04 305 Gene3D G3DSA:3.40.190.10 27 159 3.9E-24 T 09-03-2017 UA74_RS03595 0949f3912eeb2198f36aa82e91aa9127 204 Pfam PF03551 Transcriptional regulator PadR-like family 15 91 7.4E-11 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS03595 0949f3912eeb2198f36aa82e91aa9127 204 SUPERFAMILY SSF46785 11 184 1.75E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03595 0949f3912eeb2198f36aa82e91aa9127 204 Gene3D G3DSA:1.10.10.10 5 98 2.6E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00880 6407a18edc41e5c7178e8e02e1ae64e3 894 Pfam PF00932 Lamin Tail Domain 20 154 1.7E-9 T 09-03-2017 IPR001322 Lamin Tail Domain UA74_RS00880 6407a18edc41e5c7178e8e02e1ae64e3 894 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 493 786 2.0E-12 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS00880 6407a18edc41e5c7178e8e02e1ae64e3 894 SUPERFAMILY SSF56219 491 793 2.88E-29 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS00880 6407a18edc41e5c7178e8e02e1ae64e3 894 Gene3D G3DSA:3.60.10.10 490 793 3.5E-29 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS00880 6407a18edc41e5c7178e8e02e1ae64e3 894 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 852 885 2.7E-4 T 09-03-2017 IPR019931 LPXTG cell wall anchor domain UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 381 5.8E-10 T 09-03-2017 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 5.8E-10 T 09-03-2017 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 SUPERFAMILY SSF56425 236 356 3.44E-34 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 374 381 5.3E-7 T 09-03-2017 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 5.3E-7 T 09-03-2017 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 Pfam PF02910 Fumarate reductase flavoprotein C-term 485 523 2.7E-9 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 Gene3D G3DSA:3.50.50.60 353 414 7.1E-86 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 Gene3D G3DSA:3.50.50.60 3 241 7.1E-86 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 Gene3D G3DSA:3.90.700.10 242 352 1.3E-33 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 Pfam PF00890 FAD binding domain 10 396 9.6E-84 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 512 2.9E-154 T 09-03-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 Gene3D G3DSA:1.20.58.100 438 526 6.2E-15 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 SUPERFAMILY SSF51905 3 253 2.97E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 SUPERFAMILY SSF51905 360 412 2.97E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09925 7028a52056747f7e13f87d031dea0240 545 SUPERFAMILY SSF46977 440 531 5.63E-20 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SUPERFAMILY SSF48452 324 515 1.93E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Gene3D G3DSA:1.25.40.10 601 695 1.7E-16 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 586 619 0.54 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 518 551 0.011 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 552 585 3.2 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 484 517 3.6E-5 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 654 686 92.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 450 483 0.035 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 620 653 16.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Pfam PF13432 Tetratricopeptide repeat 591 649 1.4E-5 T 09-03-2017 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SUPERFAMILY SSF48452 457 681 8.72E-40 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Pfam PF13414 TPR repeat 491 532 8.6E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Gene3D G3DSA:1.25.40.10 532 600 6.9E-18 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19405 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Gene3D G3DSA:1.25.40.10 407 531 1.5E-23 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS27360 ab78542215f8d38617d811e2207ad25a 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 6.2E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS27360 ab78542215f8d38617d811e2207ad25a 209 SUPERFAMILY SSF46689 5 77 4.93E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS27360 ab78542215f8d38617d811e2207ad25a 209 SUPERFAMILY SSF48498 86 190 1.05E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS27360 ab78542215f8d38617d811e2207ad25a 209 Pfam PF13977 Bacterial transcriptional repressor 87 190 1.1E-10 T 09-03-2017 UA74_RS27360 ab78542215f8d38617d811e2207ad25a 209 Gene3D G3DSA:1.10.357.10 5 192 1.4E-36 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Gene3D G3DSA:3.40.50.740 67 144 3.0E-75 T 09-03-2017 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Gene3D G3DSA:3.40.50.740 328 553 3.0E-75 T 09-03-2017 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Pfam PF00384 Molybdopterin oxidoreductase 67 493 1.3E-66 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Pfam PF01568 Molydopterin dinucleotide binding domain 586 693 1.4E-26 T 09-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 SUPERFAMILY SSF50692 548 696 2.49E-42 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 SMART SM00926 14 64 3.5E-8 T 09-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 16 59 8.9E-7 T 09-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Gene3D G3DSA:2.20.25.90 16 65 3.6E-15 T 09-03-2017 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 SUPERFAMILY SSF53706 17 588 1.83E-159 T 09-03-2017 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Gene3D G3DSA:2.40.40.20 554 696 2.0E-48 T 09-03-2017 UA74_RS09470 558f9a1ae7f61dede56b96c8e25b4a76 711 Gene3D G3DSA:3.40.228.10 145 327 1.6E-47 T 09-03-2017 UA74_RS22055 b5307145eae587f63482cc6126d4ff84 224 Pfam PF04542 Sigma-70 region 2 47 114 6.6E-21 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS22055 b5307145eae587f63482cc6126d4ff84 224 Pfam PF04545 Sigma-70, region 4 153 201 1.4E-14 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS22055 b5307145eae587f63482cc6126d4ff84 224 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 202 7.9E-30 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS22055 b5307145eae587f63482cc6126d4ff84 224 Gene3D G3DSA:1.10.1740.10 26 137 5.9E-30 T 09-03-2017 UA74_RS22055 b5307145eae587f63482cc6126d4ff84 224 SUPERFAMILY SSF88659 146 205 7.85E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS22055 b5307145eae587f63482cc6126d4ff84 224 SUPERFAMILY SSF88946 26 125 9.26E-28 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS22055 b5307145eae587f63482cc6126d4ff84 224 Gene3D G3DSA:1.10.10.10 149 205 1.4E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07035 bb3b40fdedee3b57f229e4bfc7de7646 310 SUPERFAMILY SSF161111 18 218 3.01E-46 T 09-03-2017 UA74_RS07035 bb3b40fdedee3b57f229e4bfc7de7646 310 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 299 6.0E-73 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_RS07035 bb3b40fdedee3b57f229e4bfc7de7646 310 Gene3D G3DSA:1.20.1510.10 20 217 1.0E-46 T 09-03-2017 IPR027469 Cation efflux protein transmembrane domain UA74_RS07035 bb3b40fdedee3b57f229e4bfc7de7646 310 SUPERFAMILY SSF160240 221 297 1.44E-8 T 09-03-2017 UA74_RS07035 bb3b40fdedee3b57f229e4bfc7de7646 310 Pfam PF01545 Cation efflux family 23 217 8.1E-37 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 2.3E-246 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 09-03-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 41.015 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 SUPERFAMILY SSF48592 6 133 1.92E-72 T 09-03-2017 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 SUPERFAMILY SSF48592 404 519 1.92E-72 T 09-03-2017 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 Gene3D G3DSA:1.10.560.10 367 516 2.4E-36 T 09-03-2017 IPR027413 GroEL-like equatorial domain UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 2.2E-93 T 09-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 Gene3D G3DSA:3.50.7.10 187 366 3.6E-95 T 09-03-2017 IPR027409 GroEL-like apical domain UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 Gene3D G3DSA:1.10.560.10 6 186 1.8E-48 T 09-03-2017 IPR027413 GroEL-like equatorial domain UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 SUPERFAMILY SSF54849 136 201 2.75E-25 T 09-03-2017 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 266 289 2.5E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 396 417 2.5E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 26 52 2.5E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 82 109 2.5E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 348 373 2.5E-70 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28715 e25b18b59745e47596cea49c3de84833 539 SUPERFAMILY SSF52029 184 374 5.23E-80 T 09-03-2017 IPR027409 GroEL-like apical domain UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 Gene3D G3DSA:1.10.730.10 460 582 7.8E-34 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 SUPERFAMILY SSF55190 13 102 3.01E-18 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 SUPERFAMILY SSF52374 114 458 1.05E-84 T 09-03-2017 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 Pfam PF00750 tRNA synthetases class I (R) 118 452 1.7E-103 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 Pfam PF05746 DALR anticodon binding domain 466 582 3.5E-28 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 Gene3D G3DSA:3.30.1360.70 13 109 5.9E-27 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 582 24.94 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 SMART SM00836 466 582 8.9E-39 T 09-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 SMART SM01016 8 91 3.7E-22 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 13 91 4.2E-20 T 09-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 138 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 SUPERFAMILY SSF47323 460 582 2.49E-33 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 Gene3D G3DSA:3.40.50.620 115 458 3.3E-100 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 37 582 1.7E-140 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 1.5E-21 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 1.5E-21 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 310 331 1.5E-21 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS00165 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 1.5E-21 T 09-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_RS06800 d5efdfed01b8577721eff30d4f6178ab 676 Pfam PF02446 4-alpha-glucanotransferase 136 652 1.6E-110 T 09-03-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_RS06800 d5efdfed01b8577721eff30d4f6178ab 676 Gene3D G3DSA:3.20.20.80 128 547 5.9E-150 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS06800 d5efdfed01b8577721eff30d4f6178ab 676 Gene3D G3DSA:3.20.20.80 599 665 5.9E-150 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS06800 d5efdfed01b8577721eff30d4f6178ab 676 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 99 664 1.8E-84 T 09-03-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_RS06800 d5efdfed01b8577721eff30d4f6178ab 676 SUPERFAMILY SSF51445 123 534 5.56E-136 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS06800 d5efdfed01b8577721eff30d4f6178ab 676 SUPERFAMILY SSF51445 593 672 5.56E-136 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS19575 c0d9f8e093e890cb930bfaa87316d284 229 SMART SM00226 98 223 4.3E-42 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily UA74_RS19575 c0d9f8e093e890cb930bfaa87316d284 229 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 100 221 4.0E-24 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily UA74_RS19575 c0d9f8e093e890cb930bfaa87316d284 229 SUPERFAMILY SSF52788 98 221 3.66E-36 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily UA74_RS19575 c0d9f8e093e890cb930bfaa87316d284 229 Gene3D G3DSA:3.40.50.270 97 221 7.4E-40 T 09-03-2017 UA74_RS26745 f1c18a904b15b49aa1701513069b4d68 225 Gene3D G3DSA:1.10.10.10 124 222 1.5E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26745 f1c18a904b15b49aa1701513069b4d68 225 Pfam PF00072 Response regulator receiver domain 5 114 4.4E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS26745 f1c18a904b15b49aa1701513069b4d68 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 4.1E-26 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS26745 f1c18a904b15b49aa1701513069b4d68 225 SMART SM00448 3 113 2.9E-46 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS26745 f1c18a904b15b49aa1701513069b4d68 225 SUPERFAMILY SSF52172 3 179 1.85E-44 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS26745 f1c18a904b15b49aa1701513069b4d68 225 SMART SM00862 146 222 1.1E-24 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS26745 f1c18a904b15b49aa1701513069b4d68 225 Gene3D G3DSA:3.40.50.2300 2 123 9.3E-41 T 09-03-2017 UA74_RS10215 172f6330049c62f8620417b37f6bbfe8 294 Gene3D G3DSA:3.40.50.150 144 183 2.0E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10215 172f6330049c62f8620417b37f6bbfe8 294 Gene3D G3DSA:3.40.50.150 230 258 2.0E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10215 172f6330049c62f8620417b37f6bbfe8 294 Gene3D G3DSA:3.40.50.150 30 100 2.0E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10215 172f6330049c62f8620417b37f6bbfe8 294 Pfam PF11599 RRNA methyltransferase AviRa 9 186 1.3E-21 T 09-03-2017 IPR024268 rRNA methyltransferase AviRa KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 UA74_RS10215 172f6330049c62f8620417b37f6bbfe8 294 SUPERFAMILY SSF53335 16 191 2.09E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10215 172f6330049c62f8620417b37f6bbfe8 294 Gene3D G3DSA:1.10.287.540 102 142 6.6E-6 T 09-03-2017 IPR023218 UPF0291 structural domain UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 60 99 0.016 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 125 172 3.1E-13 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 SUPERFAMILY SSF52540 196 494 6.84E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Pfam PF02151 UvrB/uvrC motif 455 487 1.1E-6 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 SMART SM00382 235 381 6.0E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 SMART SM00382 569 745 1.1E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:1.10.8.60 755 837 8.5E-28 T 09-03-2017 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 573 591 5.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 680 694 5.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 618 636 5.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 647 665 5.1E-39 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 SMART SM01086 744 833 1.0E-32 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:1.10.1780.10 41 172 2.2E-25 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 603 621 - T 09-03-2017 IPR028299 ClpA/B, conserved site 2 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 568 738 2.6E-48 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 744 824 8.6E-22 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 240 357 2.1E-13 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:3.40.50.300 197 379 3.0E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 331 343 - T 09-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 SUPERFAMILY SSF52540 518 824 2.16E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:1.10.8.60 380 464 1.5E-33 T 09-03-2017 UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:3.40.50.300 522 695 4.9E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:3.40.50.300 727 754 4.9E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11850 071210b5fb82977b513272c88ab06ddc 848 SUPERFAMILY SSF81923 41 172 3.92E-16 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 16 405 43.073 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 SUPERFAMILY SSF69055 313 406 1.23E-24 T 09-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 SUPERFAMILY SSF51735 14 171 2.6E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 PIRSF PIRSF006205 13 410 1.1E-133 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 Gene3D G3DSA:1.10.1740.10 325 406 1.6E-28 T 09-03-2017 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 Gene3D G3DSA:3.40.50.720 11 171 3.4E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 15 403 7.7E-111 T 09-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 167 250 1.6E-36 T 09-03-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 SUPERFAMILY SSF55347 149 285 3.07E-54 T 09-03-2017 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 Pfam PF13288 DXP reductoisomerase C-terminal domain 283 400 9.2E-31 T 09-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 UA74_RS09105 fb5a9b531fd2d024de068b92cbef765b 418 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 16 155 1.2E-34 T 09-03-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 UA74_RS10305 f6719cf2c5ab9b985f37983be7601b39 589 Pfam PF02384 N-6 DNA Methylase 143 399 1.8E-22 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_RS10305 f6719cf2c5ab9b985f37983be7601b39 589 Gene3D G3DSA:3.40.50.150 153 332 6.8E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10305 f6719cf2c5ab9b985f37983be7601b39 589 SUPERFAMILY SSF53335 131 418 3.3E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12970 313a31610c19aae59b0a601aa6a0a1b5 175 Pfam PF00293 NUDIX domain 32 156 1.2E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS12970 313a31610c19aae59b0a601aa6a0a1b5 175 PIRSF PIRSF017340 1 171 4.1E-51 T 09-03-2017 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 UA74_RS12970 313a31610c19aae59b0a601aa6a0a1b5 175 SUPERFAMILY SSF55811 6 167 1.9E-29 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS12970 313a31610c19aae59b0a601aa6a0a1b5 175 Gene3D G3DSA:3.90.79.10 3 167 2.3E-47 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS12970 313a31610c19aae59b0a601aa6a0a1b5 175 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS20225 f0759db2b0839b18a3e53ccbb160f5bb 291 Gene3D G3DSA:1.10.3720.10 82 287 7.5E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20225 f0759db2b0839b18a3e53ccbb160f5bb 291 SUPERFAMILY SSF161098 85 274 1.96E-28 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20225 f0759db2b0839b18a3e53ccbb160f5bb 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 1.1E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20225 f0759db2b0839b18a3e53ccbb160f5bb 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 60 2.9E-8 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_RS07885 81e212d8ee747844bd84e3c46ad9cced 1180 Pfam PF13569 Domain of unknown function (DUF4132) 919 1097 4.0E-50 T 09-03-2017 IPR025406 Domain of unknown function DUF4132 UA74_RS07885 81e212d8ee747844bd84e3c46ad9cced 1180 Gene3D G3DSA:2.20.140.10 2 66 4.4E-18 T 09-03-2017 IPR008893 WGR domain UA74_RS07885 81e212d8ee747844bd84e3c46ad9cced 1180 Pfam PF05406 WGR domain 9 65 1.7E-10 T 09-03-2017 IPR008893 WGR domain UA74_RS03455 8ba2019c96b6028deb23de655083e7bb 316 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 3 311 2.4E-106 T 09-03-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family UA74_RS03455 8ba2019c96b6028deb23de655083e7bb 316 SUPERFAMILY SSF56059 130 312 7.34E-14 T 09-03-2017 UA74_RS03660 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 259 273 5.6E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS03660 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 56 78 5.6E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS03660 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 216 237 5.6E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS03660 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 79 99 5.6E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS03660 eaaef550779c2ec321a1644bc472c215 317 Pfam PF00487 Fatty acid desaturase 57 275 4.1E-20 T 09-03-2017 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 Gene3D G3DSA:3.40.50.1240 7 249 1.7E-85 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 146 210 3.0E-5 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 131 1.1E-25 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 SUPERFAMILY SSF53254 7 225 2.57E-69 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 233 42.307 T 09-03-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 09-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 SMART SM00855 7 192 7.9E-23 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS02210 75eac3ce109d9731819ae1a9d6389208 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 250 4.9E-108 T 09-03-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 SMART SM00420 8 59 1.5E-12 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 Gene3D G3DSA:1.10.10.10 7 56 2.1E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 SMART SM01134 73 234 2.5E-54 T 09-03-2017 UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 SUPERFAMILY SSF46785 12 60 1.45E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 6.0E-8 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 6.0E-8 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 Pfam PF00455 DeoR C terminal sensor domain 75 232 5.2E-40 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 Gene3D G3DSA:3.40.50.1360 76 224 6.0E-10 T 09-03-2017 UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 Pfam PF08220 DeoR-like helix-turn-helix domain 8 58 1.9E-13 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS00890 56fa1695d56d812a3c687e20b5b5fce3 258 SUPERFAMILY SSF100950 75 235 2.93E-25 T 09-03-2017 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 Pfam PF01568 Molydopterin dinucleotide binding domain 653 762 2.2E-9 T 09-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 PIRSF PIRSF000144 3 771 0.0 T 09-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 SUPERFAMILY SSF50692 650 770 2.49E-16 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 Gene3D G3DSA:3.40.50.740 402 639 8.6E-51 T 09-03-2017 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 Gene3D G3DSA:3.40.50.740 121 194 8.6E-51 T 09-03-2017 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 Gene3D G3DSA:2.40.40.20 652 770 7.4E-11 T 09-03-2017 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 Pfam PF00384 Molybdopterin oxidoreductase 121 501 1.3E-28 T 09-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 SUPERFAMILY SSF53706 59 644 1.07E-140 T 09-03-2017 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 Gene3D G3DSA:3.40.228.10 195 401 6.3E-59 T 09-03-2017 UA74_RS08210 4c797ad814a9880afa2e486b0f3dbf56 771 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 769 8.4E-300 T 09-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 UA74_RS23780 dd36dd1226c1425d2ecf8d3ad412d47c 342 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 18 263 1.0E-64 T 09-03-2017 IPR014145 DNA ligase D, polymerase domain UA74_RS22345 dcf92b5b5a8264072d655b5393f1c26c 181 Pfam PF07883 Cupin domain 38 90 5.9E-9 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS22345 dcf92b5b5a8264072d655b5393f1c26c 181 SUPERFAMILY SSF51182 6 105 1.56E-11 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS22345 dcf92b5b5a8264072d655b5393f1c26c 181 Gene3D G3DSA:2.60.120.10 11 103 5.0E-15 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 57 1.4E-18 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 SUPERFAMILY SSF52374 1 154 1.1E-44 T 09-03-2017 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 2.0E-49 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 2.0E-49 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 2.0E-49 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 2.0E-49 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 2.0E-49 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 34.571 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 Gene3D G3DSA:3.40.50.620 1 154 1.5E-54 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 155 5.4E-61 T 09-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 155 9.0E-4 T 09-03-2017 UA74_RS25790 d265a7d6308f0eafe5a68b409e61afc7 160 Pfam PF01467 Cytidylyltransferase-like 5 132 2.3E-19 T 09-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 SMART SM00420 6 58 2.2E-15 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 SUPERFAMILY SSF100950 75 243 8.9E-27 T 09-03-2017 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 Gene3D G3DSA:1.10.10.10 2 55 9.9E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.4E-15 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 Pfam PF00455 DeoR C terminal sensor domain 74 240 1.1E-43 T 09-03-2017 IPR014036 DeoR C-terminal sensor domain UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 SUPERFAMILY SSF46785 4 64 4.77E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 Gene3D G3DSA:3.40.50.1360 76 222 2.8E-17 T 09-03-2017 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.6E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.6E-7 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS19900 9550a33ae18cebdb0f906a40c9a5448d 261 SMART SM01134 72 242 5.1E-56 T 09-03-2017 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 98 112 2.9E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 318 340 2.9E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 355 372 2.9E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 167 187 2.9E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 392 405 2.9E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 114 124 2.9E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 60 84 2.9E-70 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF52540 9 225 2.78E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF52540 347 394 2.78E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 SMART SM00958 225 337 5.9E-66 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:3.40.50.300 396 613 1.6E-91 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF81767 224 347 6.54E-44 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF81886 614 834 7.72E-70 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:3.90.1440.10 227 347 1.1E-47 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Pfam PF01043 SecA preprotein cross-linking domain 229 337 2.4E-36 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:1.10.3060.10 642 829 3.6E-57 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Hamap MF_01382 Protein translocase subunit SecA [secA]. 2 831 19.887 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Pfam PF07517 SecA DEAD-like domain 6 380 2.2E-126 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF52540 395 612 1.16E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Pfam PF07516 SecA Wing and Scaffold domain 611 828 2.4E-65 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 ProSitePatterns PS01312 SecA family signature. 479 494 - T 09-03-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 SMART SM00957 3 381 2.2E-275 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 25 816 0.0 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:3.40.50.300 3 225 8.4E-120 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26720 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:3.40.50.300 348 395 8.4E-120 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 397 4.2E-37 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 Gene3D G3DSA:2.40.110.10 132 236 8.6E-37 T 09-03-2017 UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 129 1.5E-12 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 Gene3D G3DSA:1.20.140.10 237 399 7.2E-46 T 09-03-2017 UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 SUPERFAMILY SSF47203 245 398 7.25E-42 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 SUPERFAMILY SSF56645 2 260 5.63E-59 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 235 1.3E-19 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS13595 4f162b9e600b29782f77358a562644e1 404 Gene3D G3DSA:1.10.540.10 2 131 2.6E-29 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 141 7.3E-14 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 SMART SM00344 5 112 2.1E-37 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.0E-16 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.0E-16 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.0E-16 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 SUPERFAMILY SSF46785 4 71 8.83E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 Gene3D G3DSA:3.30.70.920 58 137 1.8E-21 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 09-03-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 Gene3D G3DSA:1.10.10.10 8 57 1.0E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 SMART SM00418 3 89 0.0035 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 SUPERFAMILY SSF54909 66 144 1.74E-13 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS13060 11fbafd5e7b9eb1ab6532a500dc65731 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 2.0E-18 T 09-03-2017 UA74_RS22705 e962cef4366b440c4d3579c9a12d997f 319 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_RS22705 e962cef4366b440c4d3579c9a12d997f 319 Gene3D G3DSA:3.40.50.720 120 287 1.6E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22705 e962cef4366b440c4d3579c9a12d997f 319 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 285 2.9E-48 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS22705 e962cef4366b440c4d3579c9a12d997f 319 Gene3D G3DSA:3.40.50.720 14 119 6.5E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22705 e962cef4366b440c4d3579c9a12d997f 319 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 30 316 1.7E-19 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 UA74_RS22705 e962cef4366b440c4d3579c9a12d997f 319 SUPERFAMILY SSF52283 9 140 2.08E-27 T 09-03-2017 UA74_RS22705 e962cef4366b440c4d3579c9a12d997f 319 SUPERFAMILY SSF51735 105 286 7.34E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS04840 62a05cab28b8b6684695d5f741d8c9e2 324 Pfam PF04228 Putative neutral zinc metallopeptidase 126 315 1.1E-18 T 09-03-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 Pfam PF00005 ABC transporter 377 524 1.4E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 SUPERFAMILY SSF52540 357 592 3.28E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 Gene3D G3DSA:3.40.50.300 359 586 1.2E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 Gene3D G3DSA:1.20.1560.10 18 322 9.5E-60 T 09-03-2017 UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 Pfam PF00664 ABC transporter transmembrane region 30 297 6.2E-36 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 SUPERFAMILY SSF90123 16 326 5.89E-60 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13775 f2fb362c3bf18169623537103bc0f039 596 SMART SM00382 386 570 3.7E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 Pfam PF02449 Beta-galactosidase 17 383 3.8E-142 T 09-03-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 SUPERFAMILY SSF52317 392 599 5.8E-54 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 Gene3D G3DSA:2.60.40.1180 607 652 8.6E-5 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 Gene3D G3DSA:3.20.20.80 14 386 1.9E-125 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 Pfam PF08533 Beta-galactosidase C-terminal domain 609 657 4.4E-5 T 09-03-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 SUPERFAMILY SSF51445 14 386 8.84E-108 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 Gene3D G3DSA:3.40.50.880 392 600 7.9E-67 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 PIRSF PIRSF001084 5 661 1.2E-246 T 09-03-2017 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS07465 2db067010f9cc82bc6ce53468f29ea08 662 Pfam PF08532 Beta-galactosidase trimerisation domain 395 599 4.1E-61 T 09-03-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS06305 629f7d4e63a1dbc31f8d20f338f841fa 151 SUPERFAMILY SSF102712 2 130 4.84E-27 T 09-03-2017 UA74_RS06305 629f7d4e63a1dbc31f8d20f338f841fa 151 Gene3D G3DSA:3.40.140.10 2 133 1.7E-34 T 09-03-2017 UA74_RS06305 629f7d4e63a1dbc31f8d20f338f841fa 151 SMART SM00232 1 136 5.4E-27 T 09-03-2017 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 UA74_RS06305 629f7d4e63a1dbc31f8d20f338f841fa 151 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 120 4.8E-28 T 09-03-2017 IPR028090 JAB domain, prokaryotic UA74_RS17790 75f77f6a41888fb74b3a8687d19d3455 172 Pfam PF04542 Sigma-70 region 2 15 79 6.5E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17790 75f77f6a41888fb74b3a8687d19d3455 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 168 9.9E-13 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17790 75f77f6a41888fb74b3a8687d19d3455 172 SUPERFAMILY SSF88659 104 167 2.06E-6 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17790 75f77f6a41888fb74b3a8687d19d3455 172 SUPERFAMILY SSF88946 4 90 4.71E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17790 75f77f6a41888fb74b3a8687d19d3455 172 Gene3D G3DSA:1.10.1740.10 4 79 1.6E-10 T 09-03-2017 UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Pfam PF01966 HD domain 68 213 3.6E-19 T 09-03-2017 IPR006674 HD domain UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Pfam PF13286 Phosphohydrolase-associated domain 322 413 6.3E-22 T 09-03-2017 IPR026875 Phosphohydrolase-associated domain UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 5 415 31.265 T 09-03-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 415 1.9E-79 T 09-03-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 SUPERFAMILY SSF109604 30 238 1.51E-55 T 09-03-2017 UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Gene3D G3DSA:1.10.3210.10 25 209 1.8E-63 T 09-03-2017 IPR006674 HD domain UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 SMART SM00471 64 223 4.5E-12 T 09-03-2017 IPR003607 HD/PDEase domain UA74_RS24475 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Gene3D G3DSA:1.10.3410.10 210 342 2.6E-18 T 09-03-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain UA74_RS05735 72a1a4cff8ca1d6986fb260bf95e76f7 109 Pfam PF06013 Proteins of 100 residues with WXG 5 88 2.3E-9 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS05735 72a1a4cff8ca1d6986fb260bf95e76f7 109 SUPERFAMILY SSF140453 5 100 6.15E-10 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS05735 72a1a4cff8ca1d6986fb260bf95e76f7 109 Gene3D G3DSA:1.10.287.1060 4 103 2.3E-10 T 09-03-2017 UA74_RS17735 3fe57e3acda6c6c9dd6c6d080581eed8 101 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 5 89 1.7E-16 T 09-03-2017 IPR010152 CRISPR-associated protein Cas2 subtype UA74_RS17735 3fe57e3acda6c6c9dd6c6d080581eed8 101 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 4 89 1.5E-29 T 09-03-2017 IPR010152 CRISPR-associated protein Cas2 subtype UA74_RS16300 dd973a8e47dfc008c6b0be16a61bca5a 841 Pfam PF01935 Domain of unknown function DUF87 420 494 9.3E-7 T 09-03-2017 IPR002789 Helicase HerA, central domain UA74_RS16300 dd973a8e47dfc008c6b0be16a61bca5a 841 Pfam PF12696 TraM recognition site of TraD and TraG 679 749 7.5E-5 T 09-03-2017 IPR032689 TraD/TraG, TraM recognition site UA74_RS16300 dd973a8e47dfc008c6b0be16a61bca5a 841 SUPERFAMILY SSF52540 397 760 1.72E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16300 dd973a8e47dfc008c6b0be16a61bca5a 841 Gene3D G3DSA:3.40.50.300 384 513 1.8E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16300 dd973a8e47dfc008c6b0be16a61bca5a 841 Gene3D G3DSA:3.40.50.300 624 768 1.8E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 288 376 5.28E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 212 293 1.0E-30 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 240 261 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 357 375 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 137 153 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 318 337 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 183 203 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 47 65 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 65 79 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 113 132 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 154 171 3.5E-87 T 09-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 132 199 2.1E-12 T 09-03-2017 IPR003029 S1 domain GO:0003676 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 302 374 5.7E-24 T 09-03-2017 IPR003029 S1 domain GO:0003676 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 44 116 7.9E-15 T 09-03-2017 IPR003029 S1 domain GO:0003676 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 217 288 8.1E-26 T 09-03-2017 IPR003029 S1 domain GO:0003676 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 118 202 5.86E-13 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 294 377 8.4E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 218 288 3.3E-28 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 303 374 4.6E-25 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 45 116 1.6E-16 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 132 199 2.0E-9 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 124 200 6.4E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 38 117 2.8E-18 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 39 141 8.21E-22 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS10735 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 218 300 1.85E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 Gene3D G3DSA:3.40.1060.10 154 289 1.9E-40 T 09-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 134 149 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 400 413 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 83 96 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 287 301 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 109 117 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 120 133 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 210 223 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 196 209 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 344 355 1.1E-46 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 2.3E-226 T 09-03-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 59.861 T 09-03-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 Gene3D G3DSA:3.30.499.10 2 153 3.6E-21 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 SUPERFAMILY SSF53732 2 466 1.83E-161 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 Gene3D G3DSA:3.30.499.10 330 467 1.9E-56 T 09-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 09-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_RS26040 46faf31044394d6db3f4aa37fde40cbf 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 4.6E-150 T 09-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF08402 TOBE domain 278 351 1.7E-7 T 09-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.140 283 342 9.2E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.100 242 282 2.7E-6 T 09-03-2017 UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.100 345 360 2.7E-6 T 09-03-2017 UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 SMART SM00382 31 214 8.3E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF00005 ABC transporter 23 164 2.6E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF52540 12 244 1.39E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:3.40.50.300 17 236 3.7E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01745 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF50331 239 359 3.64E-23 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF08402 TOBE domain 278 351 1.7E-7 T 09-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.140 283 342 9.2E-14 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.100 242 282 2.7E-6 T 09-03-2017 UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.100 345 360 2.7E-6 T 09-03-2017 UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 SMART SM00382 31 214 8.3E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF00005 ABC transporter 23 164 2.6E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF52540 12 244 1.39E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:3.40.50.300 17 236 3.7E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23645 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF50331 239 359 3.64E-23 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS05875 3c5e11853ccd999afb3d51d0c96b8838 381 Pfam PF12698 ABC-2 family transporter protein 24 370 3.8E-34 T 09-03-2017 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Gene3D G3DSA:3.40.50.620 377 600 2.7E-102 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Gene3D G3DSA:3.40.50.620 2 209 2.7E-102 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Gene3D G3DSA:3.90.740.10 217 365 7.0E-26 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 SUPERFAMILY SSF50677 213 362 3.14E-31 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 SUPERFAMILY SSF52374 1 213 5.84E-107 T 09-03-2017 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 SUPERFAMILY SSF52374 374 617 5.84E-107 T 09-03-2017 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 PRINTS PR00986 Valyl-tRNA synthetase signature 495 516 7.2E-20 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 PRINTS PR00986 Valyl-tRNA synthetase signature 250 267 7.2E-20 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 PRINTS PR00986 Valyl-tRNA synthetase signature 379 392 7.2E-20 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 PRINTS PR00986 Valyl-tRNA synthetase signature 526 544 7.2E-20 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 7.2E-20 T 09-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Pfam PF08264 Anticodon-binding domain of tRNA 651 817 3.8E-26 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Hamap MF_02005 Valine--tRNA ligase [valS]. 1 848 27.915 T 09-03-2017 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Gene3D G3DSA:1.10.730.10 601 762 3.4E-32 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 SUPERFAMILY SSF47323 626 854 5.98E-31 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 97 5.8E-19 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS20870 516ae40fb36cc06b99c97d77db4d5aa5 866 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 117 612 5.7E-67 T 09-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS16515 405638543883b5970ec2092552694ca8 314 Pfam PF00698 Acyl transferase domain 1 290 4.5E-53 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16515 405638543883b5970ec2092552694ca8 314 Gene3D G3DSA:3.40.366.10 189 300 1.9E-76 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16515 405638543883b5970ec2092552694ca8 314 Gene3D G3DSA:3.40.366.10 1 123 1.9E-76 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16515 405638543883b5970ec2092552694ca8 314 Gene3D G3DSA:3.30.70.250 128 188 5.5E-10 T 09-03-2017 UA74_RS16515 405638543883b5970ec2092552694ca8 314 SUPERFAMILY SSF52151 190 287 3.4E-70 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16515 405638543883b5970ec2092552694ca8 314 SUPERFAMILY SSF52151 1 129 3.4E-70 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16515 405638543883b5970ec2092552694ca8 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 298 7.8E-118 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16515 405638543883b5970ec2092552694ca8 314 SUPERFAMILY SSF55048 128 189 1.06E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS22245 7479bab8c12ee07497e4eafdc15034b6 261 Gene3D G3DSA:3.20.20.150 11 238 4.7E-35 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS22245 7479bab8c12ee07497e4eafdc15034b6 261 Pfam PF01261 Xylose isomerase-like TIM barrel 78 211 1.5E-18 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS22245 7479bab8c12ee07497e4eafdc15034b6 261 SUPERFAMILY SSF51658 11 221 1.43E-27 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS28430 7ef455571f942989a38218c003c5e503 217 SUPERFAMILY SSF50475 16 217 3.1E-63 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS28430 7ef455571f942989a38218c003c5e503 217 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 37 122 1.4E-18 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS28430 7ef455571f942989a38218c003c5e503 217 PIRSF PIRSF000190 2 217 9.6E-77 T 09-03-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS28430 7ef455571f942989a38218c003c5e503 217 Gene3D G3DSA:2.30.110.10 20 217 8.2E-80 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS28430 7ef455571f942989a38218c003c5e503 217 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 6 217 4.2E-75 T 09-03-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS28430 7ef455571f942989a38218c003c5e503 217 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 14 217 36.222 T 09-03-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS28430 7ef455571f942989a38218c003c5e503 217 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 187 200 - T 09-03-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS28430 7ef455571f942989a38218c003c5e503 217 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 177 217 3.7E-18 T 09-03-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS30450 d0ca254113657cae3cdeac159be1899a 185 SMART SM00393 105 184 8.2E-20 T 09-03-2017 IPR001374 R3H domain GO:0003676 UA74_RS30450 d0ca254113657cae3cdeac159be1899a 185 Pfam PF01424 R3H domain 130 181 2.9E-13 T 09-03-2017 IPR001374 R3H domain GO:0003676 UA74_RS30450 d0ca254113657cae3cdeac159be1899a 185 SUPERFAMILY SSF82708 136 183 1.12E-9 T 09-03-2017 IPR001374 R3H domain GO:0003676 UA74_RS30450 d0ca254113657cae3cdeac159be1899a 185 Gene3D G3DSA:3.30.1370.50 116 184 1.7E-23 T 09-03-2017 IPR001374 R3H domain GO:0003676 UA74_RS30450 d0ca254113657cae3cdeac159be1899a 185 Gene3D G3DSA:3.30.300.120 38 115 4.2E-20 T 09-03-2017 UA74_RS14440 078bca0197efb716eb2ff5858021be6b 175 SUPERFAMILY SSF109854 6 156 2.93E-6 T 09-03-2017 UA74_RS14440 078bca0197efb716eb2ff5858021be6b 175 Pfam PF12867 DinB superfamily 12 162 5.4E-21 T 09-03-2017 IPR024775 DinB-like domain UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 Gene3D G3DSA:1.10.10.10 133 227 4.6E-35 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SMART SM00421 164 221 4.3E-26 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SUPERFAMILY SSF52172 13 146 2.56E-29 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 Pfam PF00072 Response regulator receiver domain 16 128 2.0E-21 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 Gene3D G3DSA:3.40.50.2300 12 132 3.0E-30 T 09-03-2017 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SMART SM00448 14 128 9.2E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 5.5E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SUPERFAMILY SSF46894 150 227 3.03E-23 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 8.7E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 8.7E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS27990 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 8.7E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21545 5845db6df5df2f602c9dfc20d9ee9254 420 Gene3D G3DSA:3.30.565.10 293 414 5.1E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21545 5845db6df5df2f602c9dfc20d9ee9254 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 410 6.6E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21545 5845db6df5df2f602c9dfc20d9ee9254 420 SUPERFAMILY SSF55874 296 409 9.04E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21545 5845db6df5df2f602c9dfc20d9ee9254 420 SMART SM00387 315 411 8.1E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21545 5845db6df5df2f602c9dfc20d9ee9254 420 Pfam PF07730 Histidine kinase 206 272 6.2E-17 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS05145 57792663e825e3b9957d351d883f2f3c 393 Gene3D G3DSA:3.40.50.2000 226 330 3.7E-14 T 09-03-2017 UA74_RS05145 57792663e825e3b9957d351d883f2f3c 393 Pfam PF00534 Glycosyl transferases group 1 276 342 8.9E-12 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS05145 57792663e825e3b9957d351d883f2f3c 393 Pfam PF13439 Glycosyltransferase Family 4 31 182 6.8E-12 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS05145 57792663e825e3b9957d351d883f2f3c 393 SUPERFAMILY SSF53756 17 385 1.53E-39 T 09-03-2017 UA74_RS26625 a761ebe8e54bd08fc6a38127be4d6fbd 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.365 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS26625 a761ebe8e54bd08fc6a38127be4d6fbd 84 Pfam PF02467 Transcription factor WhiB 3 71 1.4E-26 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 357 381 5.4E-23 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 255 272 5.4E-23 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 40 59 5.4E-23 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 275 301 5.4E-23 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 392 402 5.4E-23 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 402 425 5.4E-23 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 402 413 1.9E-13 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 266 283 1.9E-13 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 318 329 1.9E-13 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 393 402 1.9E-13 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 Gene3D G3DSA:1.10.630.10 11 453 1.3E-116 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 Pfam PF00067 Cytochrome P450 13 437 9.2E-84 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS18685 e8a75a5afacc45052c15dce2d60ff901 455 SUPERFAMILY SSF48264 11 451 1.1E-111 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.82 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 SUPERFAMILY SSF56053 84 178 1.23E-35 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 4.9E-33 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 4.9E-33 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 4.9E-33 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 Pfam PF00347 Ribosomal protein L6 92 165 6.5E-20 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 Pfam PF00347 Ribosomal protein L6 11 83 4.7E-18 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 09-03-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.9E-73 T 09-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 SUPERFAMILY SSF56053 1 83 1.31E-25 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 PIRSF PIRSF002162 1 178 8.8E-46 T 09-03-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 Gene3D G3DSA:3.90.930.12 2 83 4.3E-29 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03005 e5b607df38fc7d2b505c413d8809569a 179 Gene3D G3DSA:3.90.930.12 84 178 1.4E-38 T 09-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS07995 4645f66b8dc8a7141cb381d3d60cbb34 318 SUPERFAMILY SSF82689 214 311 1.31E-14 T 09-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 UA74_RS07995 4645f66b8dc8a7141cb381d3d60cbb34 318 Gene3D G3DSA:2.30.30.60 165 207 4.0E-11 T 09-03-2017 UA74_RS07995 4645f66b8dc8a7141cb381d3d60cbb34 318 SUPERFAMILY SSF50182 149 207 1.86E-11 T 09-03-2017 IPR010920 LSM domain UA74_RS07995 4645f66b8dc8a7141cb381d3d60cbb34 318 SUPERFAMILY SSF82861 94 148 1.23E-11 T 09-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 UA74_RS07995 4645f66b8dc8a7141cb381d3d60cbb34 318 Gene3D G3DSA:3.30.70.100 221 305 2.5E-7 T 09-03-2017 UA74_RS07995 4645f66b8dc8a7141cb381d3d60cbb34 318 Pfam PF00924 Mechanosensitive ion channel 107 306 2.8E-39 T 09-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 395 1.2E-51 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 Gene3D G3DSA:3.40.50.1100 117 195 1.3E-22 T 09-03-2017 UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 PIRSF PIRSF001413 11 414 9.4E-160 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 20 409 52.745 T 09-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 SUPERFAMILY SSF53686 21 408 4.06E-147 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 25 406 3.6E-183 T 09-03-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 Gene3D G3DSA:3.40.50.1100 196 410 1.2E-97 T 09-03-2017 UA74_RS10125 bc79acadab170e151b60b9b625ec58a8 417 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 99 113 - T 09-03-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_RS04445 92a90fe644a7aafe4cd4dcf2257d25b5 370 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 225 238 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_RS04445 92a90fe644a7aafe4cd4dcf2257d25b5 370 SUPERFAMILY SSF53383 25 368 2.26E-77 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS04445 92a90fe644a7aafe4cd4dcf2257d25b5 370 Pfam PF00155 Aminotransferase class I and II 37 367 1.5E-42 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS04445 92a90fe644a7aafe4cd4dcf2257d25b5 370 Gene3D G3DSA:3.90.1150.10 246 368 2.8E-23 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS04445 92a90fe644a7aafe4cd4dcf2257d25b5 370 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 14 368 4.4E-169 T 09-03-2017 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria UA74_RS04445 92a90fe644a7aafe4cd4dcf2257d25b5 370 Gene3D G3DSA:3.40.640.10 49 245 5.0E-37 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 161 185 1.0E-9 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 1.0E-9 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 130 1.0E-9 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 6 194 3.7E-35 T 09-03-2017 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 SUPERFAMILY SSF51905 1 185 8.74E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 SUPERFAMILY SSF51905 124 318 1.3E-13 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 1.1E-11 T 09-03-2017 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-11 T 09-03-2017 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.1E-11 T 09-03-2017 UA74_RS19590 9211c8bd574f9b8f4f22f49f9122ec7a 357 Gene3D G3DSA:3.50.50.60 3 195 3.0E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15945 c993bb5ce51c2aaceabeb28abfe11f1a 376 Gene3D G3DSA:1.10.443.10 167 350 6.5E-31 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15945 c993bb5ce51c2aaceabeb28abfe11f1a 376 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 60 113 5.2E-11 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_RS15945 c993bb5ce51c2aaceabeb28abfe11f1a 376 Pfam PF00589 Phage integrase family 167 343 6.0E-14 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15945 c993bb5ce51c2aaceabeb28abfe11f1a 376 Gene3D G3DSA:1.10.150.130 60 151 4.1E-17 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS15945 c993bb5ce51c2aaceabeb28abfe11f1a 376 SUPERFAMILY SSF56349 59 351 7.65E-54 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS29480 c8c440fe9f34097670eeff7de0a0204e 291 SUPERFAMILY SSF46955 2 107 6.59E-24 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS29480 c8c440fe9f34097670eeff7de0a0204e 291 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 9.5E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS29480 c8c440fe9f34097670eeff7de0a0204e 291 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 9.5E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS29480 c8c440fe9f34097670eeff7de0a0204e 291 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 9.5E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS29480 c8c440fe9f34097670eeff7de0a0204e 291 Pfam PF00376 MerR family regulatory protein 3 40 1.1E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS29480 c8c440fe9f34097670eeff7de0a0204e 291 Gene3D G3DSA:1.10.1660.10 1 103 2.4E-25 T 09-03-2017 UA74_RS29480 c8c440fe9f34097670eeff7de0a0204e 291 SMART SM00422 2 71 1.1E-21 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS08640 e302a95580238b1afe5593f3e0a5a338 189 Hamap MF_01114 Regulatory protein RecX [recX]. 11 177 15.859 T 09-03-2017 IPR003783 Regulatory protein RecX GO:0006282 UA74_RS08640 e302a95580238b1afe5593f3e0a5a338 189 Gene3D G3DSA:1.10.10.10 76 117 4.0E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08640 e302a95580238b1afe5593f3e0a5a338 189 Pfam PF02631 RecX family 53 172 1.8E-28 T 09-03-2017 IPR003783 Regulatory protein RecX GO:0006282 UA74_RS08640 e302a95580238b1afe5593f3e0a5a338 189 Gene3D G3DSA:1.10.10.10 29 74 3.5E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 SMART SM00418 37 115 1.4E-19 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 6.3E-17 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 6.3E-17 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 6.3E-17 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 6.3E-17 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 SUPERFAMILY SSF46785 31 117 3.92E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 Pfam PF01022 Bacterial regulatory protein, arsR family 44 91 6.6E-10 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS16960 5cd604d48d5a7166c3a263c1c497103c 138 Gene3D G3DSA:1.10.10.10 7 118 1.4E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 SUPERFAMILY SSF52540 2 216 1.51E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 SUPERFAMILY SSF52540 257 482 1.21E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 SMART SM00382 23 212 1.3E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 SMART SM00382 276 470 7.6E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 Pfam PF00005 ABC transporter 14 164 1.2E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 Pfam PF00005 ABC transporter 268 421 3.7E-20 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 Gene3D G3DSA:3.40.50.300 255 485 4.9E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27305 ab2e8965ef2a59cf53cf9d2cf556a5a9 495 Gene3D G3DSA:3.40.50.300 2 216 6.2E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 Gene3D G3DSA:1.10.10.10 23 147 8.9E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 SMART SM00347 31 131 9.3E-23 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 SUPERFAMILY SSF46785 22 144 2.37E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 Pfam PF01047 MarR family 38 95 9.0E-14 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 298 366 3.3E-12 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 SUPERFAMILY SSF56214 206 290 1.05E-13 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 SUPERFAMILY SSF56214 298 391 2.35E-16 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 Gene3D G3DSA:3.90.470.20 194 308 3.5E-21 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS21065 601268c2aa0b5f71907e213bc6f9cf1e 437 Gene3D G3DSA:3.90.470.20 309 399 6.0E-13 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS05090 49ace632fd864e66d1634742014e15a8 159 SUPERFAMILY SSF102405 2 155 2.93E-11 T 09-03-2017 UA74_RS05090 49ace632fd864e66d1634742014e15a8 159 Gene3D G3DSA:3.40.50.450 38 152 2.3E-6 T 09-03-2017 UA74_RS15830 3b3b6dbaa1f73aceb20020a56465aa00 391 Gene3D G3DSA:1.10.260.40 13 58 4.2E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS15830 3b3b6dbaa1f73aceb20020a56465aa00 391 SUPERFAMILY SSF48452 181 294 2.74E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS15830 3b3b6dbaa1f73aceb20020a56465aa00 391 Pfam PF13560 Helix-turn-helix domain 9 66 2.5E-6 T 09-03-2017 UA74_RS15830 3b3b6dbaa1f73aceb20020a56465aa00 391 Gene3D G3DSA:1.25.40.10 106 294 6.5E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 Pfam PF07724 AAA domain (Cdc48 subfamily) 127 318 2.4E-40 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 5 423 45.211 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 SUPERFAMILY SSF52540 71 411 3.02E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 Gene3D G3DSA:1.10.8.60 324 422 1.2E-30 T 09-03-2017 UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 SMART SM01086 325 419 6.8E-27 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 419 3.0E-154 T 09-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 Gene3D G3DSA:3.40.50.300 72 268 1.9E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 Gene3D G3DSA:3.40.50.300 302 319 1.9E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 325 402 3.6E-13 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 SUPERFAMILY SSF57716 8 44 1.18E-7 T 09-03-2017 UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 SMART SM00382 126 279 2.2E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 SMART SM00994 7 47 9.5E-17 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_RS22510 76651e7228757894a44185c4a6b92b5b 436 Pfam PF06689 ClpX C4-type zinc finger 9 45 8.9E-16 T 09-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_RS14405 8e2581627a2004b0b9b3f912d7a16e7e 413 Pfam PF07690 Major Facilitator Superfamily 25 278 2.5E-30 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS14405 8e2581627a2004b0b9b3f912d7a16e7e 413 SUPERFAMILY SSF103473 6 392 1.44E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14405 8e2581627a2004b0b9b3f912d7a16e7e 413 Gene3D G3DSA:1.20.1250.20 217 390 9.0E-13 T 09-03-2017 UA74_RS14405 8e2581627a2004b0b9b3f912d7a16e7e 413 Gene3D G3DSA:1.20.1250.20 17 196 3.0E-28 T 09-03-2017 UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 9.6E-38 T 09-03-2017 UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 Gene3D G3DSA:3.40.50.720 3 248 8.0E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.4E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24220 78e9331fc722487d5a72ccd7bee734a7 250 SUPERFAMILY SSF51735 2 248 6.82E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 SUPERFAMILY SSF52172 2 128 5.55E-34 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 6.2E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 SUPERFAMILY SSF46894 144 215 7.48E-23 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 Gene3D G3DSA:1.10.10.10 126 216 7.1E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 Pfam PF00072 Response regulator receiver domain 4 118 2.9E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.3E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.3E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.3E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 Gene3D G3DSA:3.40.50.2300 2 125 1.2E-38 T 09-03-2017 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 SMART SM00448 2 117 7.1E-31 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS23380 5b4fdc7fb08443bf52feeca7865a35cd 221 SMART SM00421 152 209 1.8E-26 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29650 2562127a6c82e52b814844f65607a28d 95 SUPERFAMILY SSF54909 1 87 1.36E-21 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS29650 2562127a6c82e52b814844f65607a28d 95 Gene3D G3DSA:3.30.70.1060 11 86 1.3E-18 T 09-03-2017 UA74_RS29650 2562127a6c82e52b814844f65607a28d 95 Pfam PF03795 YCII-related domain 12 85 1.5E-13 T 09-03-2017 IPR005545 YCII-related UA74_RS00905 ee56a3bb4cfea5af3792104fbcecfc94 521 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 25 3.4E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UA74_RS00905 ee56a3bb4cfea5af3792104fbcecfc94 521 SUPERFAMILY SSF53850 35 517 4.34E-89 T 09-03-2017 UA74_RS00905 ee56a3bb4cfea5af3792104fbcecfc94 521 Gene3D G3DSA:3.10.105.10 286 489 6.4E-33 T 09-03-2017 UA74_RS00905 ee56a3bb4cfea5af3792104fbcecfc94 521 PIRSF PIRSF002741 1 518 3.7E-56 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS00905 ee56a3bb4cfea5af3792104fbcecfc94 521 Gene3D G3DSA:3.40.190.10 144 285 3.6E-30 T 09-03-2017 UA74_RS00905 ee56a3bb4cfea5af3792104fbcecfc94 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 432 7.3E-56 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 2 292 2.6E-105 T 09-03-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 SUPERFAMILY SSF51735 2 143 5.8E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 143 1.7E-33 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 162 272 2.2E-22 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 230 242 - T 09-03-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 5.6E-33 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 5.6E-33 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 5.6E-33 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 151 179 5.6E-33 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 226 253 5.6E-33 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 SMART SM01350 162 305 1.7E-4 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 SUPERFAMILY SSF48179 160 292 2.31E-40 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 Gene3D G3DSA:3.40.50.720 2 163 1.3E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00015 9f598af95aa790409b6fca402e0565be 306 Gene3D G3DSA:1.10.1040.10 164 272 6.4E-34 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Pfam PF00122 E1-E2 ATPase 215 433 1.7E-61 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 193 210 7.2E-6 T 09-03-2017 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 91 109 7.2E-6 T 09-03-2017 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 245 264 7.2E-6 T 09-03-2017 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 109 126 7.2E-6 T 09-03-2017 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Pfam PF00403 Heavy-metal-associated domain 20 75 1.0E-9 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 665 677 6.0E-26 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 292 306 6.0E-26 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 578 6.0E-26 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 589 599 6.0E-26 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 661 6.0E-26 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 442 456 6.0E-26 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:3.30.70.100 12 78 5.5E-21 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Pfam PF00702 haloacid dehalogenase-like hydrolase 438 656 1.8E-45 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF81653 247 339 2.48E-22 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF55008 11 81 2.75E-18 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 444 450 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 164 744 1.8E-172 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF56784 539 742 1.65E-53 T 09-03-2017 IPR023214 HAD-like domain UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF56784 440 460 1.65E-53 T 09-03-2017 IPR023214 HAD-like domain UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:3.40.50.1000 413 457 1.5E-52 T 09-03-2017 IPR023214 HAD-like domain UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:3.40.50.1000 570 710 1.5E-52 T 09-03-2017 IPR023214 HAD-like domain UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:3.40.1110.10 458 569 3.0E-21 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 ProSitePatterns PS01229 Hypothetical cof family signature 2. 642 664 - T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 ProSitePatterns PS01047 Heavy-metal-associated domain. 19 47 - T 09-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 217 721 4.8E-82 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:2.70.150.10 213 339 1.6E-22 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF81665 343 434 5.75E-13 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF81665 93 104 5.75E-13 T 09-03-2017 UA74_RS17255 3e29095bf9fb1b49d1325e85a0dba9a3 761 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 745 9.8E-148 T 09-03-2017 UA74_RS12610 92670f7cbc4785798391a66c1c60a5be 489 SUPERFAMILY SSF101960 55 486 3.27E-140 T 09-03-2017 UA74_RS12610 92670f7cbc4785798391a66c1c60a5be 489 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 33 480 5.2E-219 T 09-03-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 UA74_RS12610 92670f7cbc4785798391a66c1c60a5be 489 Pfam PF01458 Uncharacterized protein family (UPF0051) 235 460 1.8E-76 T 09-03-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 UA74_RS14895 c5c6e3c5cdd9f0fb6ed18545c261ef3b 342 SUPERFAMILY SSF53474 280 310 1.5E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14895 c5c6e3c5cdd9f0fb6ed18545c261ef3b 342 SUPERFAMILY SSF53474 74 228 1.5E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14895 c5c6e3c5cdd9f0fb6ed18545c261ef3b 342 Pfam PF10503 Esterase PHB depolymerase 79 194 1.1E-9 T 09-03-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 UA74_RS14895 c5c6e3c5cdd9f0fb6ed18545c261ef3b 342 Gene3D G3DSA:3.40.50.1820 12 336 1.2E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12650 785ee35f36a4a4e7728f7c449d550751 292 Pfam PF13560 Helix-turn-helix domain 25 86 2.0E-10 T 09-03-2017 UA74_RS12650 785ee35f36a4a4e7728f7c449d550751 292 SUPERFAMILY SSF47413 21 85 1.19E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS12650 785ee35f36a4a4e7728f7c449d550751 292 Gene3D G3DSA:1.10.260.40 23 79 6.2E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 SUPERFAMILY SSF102114 25 319 9.94E-61 T 09-03-2017 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 Hamap MF_01694 Biotin synthase [bioB]. 11 334 36.982 T 09-03-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 241 329 8.0E-13 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 Gene3D G3DSA:3.20.20.70 24 330 1.2E-76 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 SMART SM00876 241 333 4.1E-28 T 09-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 PIRSF PIRSF001619 5 339 1.0E-99 T 09-03-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 SMART SM00729 63 270 1.6E-32 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 Pfam PF04055 Radical SAM superfamily 70 229 1.9E-11 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS09895 8809aa5d6acb0299c80823996f2d541f 340 TIGRFAM TIGR00433 bioB: biotin synthase 35 330 5.2E-102 T 09-03-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_RS19470 3c4f0b57077754333594b9a85783d558 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 7.5E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS19470 3c4f0b57077754333594b9a85783d558 211 SUPERFAMILY SSF46689 2 85 2.1E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS19470 3c4f0b57077754333594b9a85783d558 211 SUPERFAMILY SSF48498 82 195 1.22E-24 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS19470 3c4f0b57077754333594b9a85783d558 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS19470 3c4f0b57077754333594b9a85783d558 211 Gene3D G3DSA:1.10.357.10 74 198 1.0E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS19470 3c4f0b57077754333594b9a85783d558 211 Gene3D G3DSA:1.10.10.60 2 67 1.1E-23 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 Pfam PF00246 Zinc carboxypeptidase 134 406 4.0E-63 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 SUPERFAMILY SSF53187 123 421 1.26E-78 T 09-03-2017 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 312 322 - T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 SMART SM00631 126 408 9.0E-86 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 174 196 - T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 Gene3D G3DSA:3.40.630.10 123 414 3.8E-85 T 09-03-2017 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 174 188 7.2E-13 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 152 164 7.2E-13 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 309 322 7.2E-13 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS09940 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 250 258 7.2E-13 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS06680 73b999f17250ed3d77cb4bbbcff89150 248 Pfam PF09339 IclR helix-turn-helix domain 3 52 8.3E-16 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS06680 73b999f17250ed3d77cb4bbbcff89150 248 SUPERFAMILY SSF55781 58 245 2.62E-50 T 09-03-2017 IPR029016 GAF domain-like UA74_RS06680 73b999f17250ed3d77cb4bbbcff89150 248 Pfam PF01614 Bacterial transcriptional regulator 119 241 2.5E-34 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS06680 73b999f17250ed3d77cb4bbbcff89150 248 Gene3D G3DSA:3.30.450.40 71 246 1.3E-56 T 09-03-2017 IPR029016 GAF domain-like UA74_RS06680 73b999f17250ed3d77cb4bbbcff89150 248 SUPERFAMILY SSF46785 1 72 2.28E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06680 73b999f17250ed3d77cb4bbbcff89150 248 SMART SM00346 1 90 6.0E-21 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS06680 73b999f17250ed3d77cb4bbbcff89150 248 Gene3D G3DSA:1.10.10.10 1 70 7.9E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19235 69a9f8bd45a6bab604fe1044eae67215 265 SMART SM00530 12 85 1.4E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS19235 69a9f8bd45a6bab604fe1044eae67215 265 Pfam PF13560 Helix-turn-helix domain 8 88 1.4E-19 T 09-03-2017 UA74_RS19235 69a9f8bd45a6bab604fe1044eae67215 265 Gene3D G3DSA:1.10.260.40 6 83 3.9E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS19235 69a9f8bd45a6bab604fe1044eae67215 265 SUPERFAMILY SSF47413 31 82 4.15E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF16350 FAD dependent oxidoreductase central domain 412 467 5.8E-19 T 09-03-2017 IPR032503 FAD dependent oxidoreductase, central domain UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.1360.120 465 549 4.3E-13 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.1360.120 625 720 1.1E-23 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.50.50.60 4 76 1.8E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.50.50.60 373 453 1.8E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.50.50.60 146 225 1.8E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF01571 Aminomethyltransferase folate-binding domain 469 742 1.5E-73 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 750 841 9.8E-18 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF54373 326 372 6.28E-21 T 09-03-2017 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF54373 226 298 6.28E-21 T 09-03-2017 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.9.10 93 145 4.9E-49 T 09-03-2017 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.9.10 332 372 4.9E-49 T 09-03-2017 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.9.10 226 299 4.9E-49 T 09-03-2017 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF101790 767 853 5.89E-22 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.70.1400 550 619 1.2E-17 T 09-03-2017 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF01266 FAD dependent oxidoreductase 6 409 1.7E-44 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF51905 5 226 8.42E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF51905 373 455 8.42E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:2.40.30.110 764 839 1.4E-22 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS06685 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF103025 462 762 9.26E-93 T 09-03-2017 UA74_RS19910 1ad4eaaf525c9b0155305ffc8b767aab 311 Pfam PF00294 pfkB family carbohydrate kinase 13 282 3.4E-38 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS19910 1ad4eaaf525c9b0155305ffc8b767aab 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 242 255 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS19910 1ad4eaaf525c9b0155305ffc8b767aab 311 Gene3D G3DSA:3.40.1190.20 31 301 1.5E-65 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS19910 1ad4eaaf525c9b0155305ffc8b767aab 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS19910 1ad4eaaf525c9b0155305ffc8b767aab 311 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 288 2.6E-82 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_RS19910 1ad4eaaf525c9b0155305ffc8b767aab 311 SUPERFAMILY SSF53613 2 282 2.34E-58 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS19910 1ad4eaaf525c9b0155305ffc8b767aab 311 PIRSF PIRSF000535 1 304 1.4E-72 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_RS14650 a1c09e4168a6233d9f354f448e11521d 165 Gene3D G3DSA:1.10.10.10 14 147 1.3E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14650 a1c09e4168a6233d9f354f448e11521d 165 SMART SM00347 32 135 7.3E-15 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS14650 a1c09e4168a6233d9f354f448e11521d 165 SUPERFAMILY SSF46785 11 148 8.59E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14650 a1c09e4168a6233d9f354f448e11521d 165 Pfam PF12802 MarR family 38 97 7.8E-11 T 09-03-2017 UA74_RS11500 d2ec46cd7feed8b5900fc85f7c88d386 433 SUPERFAMILY SSF56176 356 432 4.91E-22 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS11500 d2ec46cd7feed8b5900fc85f7c88d386 433 Pfam PF01595 Domain of unknown function DUF21 13 205 6.4E-34 T 09-03-2017 IPR002550 Domain of unknown function DUF21 UA74_RS11500 d2ec46cd7feed8b5900fc85f7c88d386 433 Gene3D G3DSA:3.30.465.10 351 432 1.5E-26 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS11500 d2ec46cd7feed8b5900fc85f7c88d386 433 Gene3D G3DSA:3.10.580.10 212 350 2.5E-13 T 09-03-2017 UA74_RS11500 d2ec46cd7feed8b5900fc85f7c88d386 433 SUPERFAMILY SSF54631 212 351 4.55E-24 T 09-03-2017 UA74_RS11500 d2ec46cd7feed8b5900fc85f7c88d386 433 SMART SM01091 358 433 2.4E-22 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS11500 d2ec46cd7feed8b5900fc85f7c88d386 433 Pfam PF03471 Transporter associated domain 361 432 8.3E-23 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 SUPERFAMILY SSF48208 187 360 2.04E-70 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 SUPERFAMILY SSF48208 387 549 2.04E-70 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 SUPERFAMILY SSF52833 2 126 1.85E-29 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Gene3D G3DSA:1.50.10.10 189 319 2.6E-14 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Pfam PF03190 Protein of unknown function, DUF255 3 163 1.3E-73 T 09-03-2017 IPR004879 Domain of unknown function DUF255 UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Gene3D G3DSA:3.40.30.10 20 147 7.6E-33 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 468 522 0.051 T 09-03-2017 UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 PIRSF PIRSF006402 1 692 2.5E-201 T 09-03-2017 IPR024705 Spermatogenesis-associated protein 20 UA74_RS04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Gene3D G3DSA:1.50.10.10 414 531 8.1E-7 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS21470 4644aaa88b9878635aa1ecc70a90c078 358 Gene3D G3DSA:3.40.710.10 65 204 1.8E-15 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS21470 4644aaa88b9878635aa1ecc70a90c078 358 Gene3D G3DSA:3.40.710.10 244 350 1.8E-15 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS21470 4644aaa88b9878635aa1ecc70a90c078 358 Pfam PF13354 Beta-lactamase enzyme family 71 274 1.4E-13 T 09-03-2017 UA74_RS21470 4644aaa88b9878635aa1ecc70a90c078 358 SUPERFAMILY SSF56601 64 204 2.73E-16 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 3.6E-41 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 3.6E-41 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 3.6E-41 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 3.6E-41 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 3.6E-41 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 3.6E-41 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82866 290 489 7.46E-46 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82714 183 261 2.09E-11 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82714 708 791 6.93E-9 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82866 791 1015 5.89E-49 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.2090.10 708 794 1.6E-7 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82693 559 649 7.32E-7 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.70.1430 562 649 9.6E-6 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82693 135 180 1.48E-12 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82693 266 321 1.48E-12 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.70.1430 42 135 5.9E-24 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Pfam PF00873 AcrB/AcrD/AcrF family 5 1011 4.3E-224 T 09-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82693 42 129 2.75E-21 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:1.10.3850.10 271 490 1.7E-59 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:1.10.3850.10 798 1014 5.7E-59 T 09-03-2017 UA74_RS21070 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.2090.10 183 261 2.8E-10 T 09-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 211 362 2.4E-13 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SMART SM01002 147 309 1.1E-14 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Gene3D G3DSA:3.40.50.1770 13 174 4.9E-22 T 09-03-2017 UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 13 125 1.4E-13 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SMART SM01003 7 144 1.5E-18 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Gene3D G3DSA:3.40.50.720 175 279 1.6E-5 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SUPERFAMILY SSF51735 144 315 7.35E-17 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20490 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SUPERFAMILY SSF52283 12 180 2.21E-27 T 09-03-2017 UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 Pfam PF00501 AMP-binding enzyme 34 447 8.5E-81 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:2.30.38.10 371 440 4.3E-21 T 09-03-2017 UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:3.40.50.980 203 359 4.1E-36 T 09-03-2017 UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 532 1.0E-10 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:3.30.300.30 442 540 6.9E-25 T 09-03-2017 UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 SUPERFAMILY SSF56801 12 543 3.92E-132 T 09-03-2017 UA74_RS17570 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:3.40.50.980 34 202 7.6E-27 T 09-03-2017 UA74_RS08565 ed941bbeaea302793ce0c9bc044caacf 126 Gene3D G3DSA:2.40.50.140 39 124 7.0E-8 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS08565 ed941bbeaea302793ce0c9bc044caacf 126 PIRSF PIRSF006910 1 125 8.5E-50 T 09-03-2017 IPR016499 Nucleic acid binding protein, Rv2694c, predicted UA74_RS04495 278ea8bf4104cb66bc4d69208c42f9bd 271 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 256 1.1E-80 T 09-03-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 UA74_RS04495 278ea8bf4104cb66bc4d69208c42f9bd 271 Pfam PF00809 Pterin binding enzyme 1 242 6.1E-67 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS04495 278ea8bf4104cb66bc4d69208c42f9bd 271 Gene3D G3DSA:3.20.20.20 1 259 2.2E-82 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS04495 278ea8bf4104cb66bc4d69208c42f9bd 271 SUPERFAMILY SSF51717 1 259 3.4E-76 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS12835 e3a58e0f999c2371607b018317749caa 141 SUPERFAMILY SSF50475 14 105 1.87E-10 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS12835 e3a58e0f999c2371607b018317749caa 141 Gene3D G3DSA:2.30.110.10 13 109 6.5E-9 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS12835 e3a58e0f999c2371607b018317749caa 141 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 9 128 7.0E-33 T 09-03-2017 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 SUPERFAMILY SSF55785 153 279 9.02E-21 T 09-03-2017 IPR000014 PAS domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 Pfam PF00990 Diguanylate cyclase, GGDEF domain 293 448 8.2E-30 T 09-03-2017 IPR000160 GGDEF domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 Pfam PF00989 PAS fold 167 277 5.0E-10 T 09-03-2017 IPR013767 PAS fold GO:0006355 UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 SMART SM00052 463 711 1.2E-34 T 09-03-2017 IPR001633 EAL domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 SUPERFAMILY SSF141868 472 718 2.62E-44 T 09-03-2017 IPR001633 EAL domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 SMART SM00091 166 232 6.8E-12 T 09-03-2017 IPR000014 PAS domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 Pfam PF00563 EAL domain 471 706 2.3E-42 T 09-03-2017 IPR001633 EAL domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 SMART SM00267 281 453 7.8E-35 T 09-03-2017 IPR000160 GGDEF domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 Gene3D G3DSA:3.30.70.270 294 458 1.4E-38 T 09-03-2017 UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 Gene3D G3DSA:3.20.20.450 467 717 1.1E-55 T 09-03-2017 IPR001633 EAL domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 162 280 1.1E-13 T 09-03-2017 IPR000014 PAS domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 Gene3D G3DSA:3.30.450.20 153 277 1.1E-21 T 09-03-2017 UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 290 450 4.2E-27 T 09-03-2017 IPR000160 GGDEF domain UA74_RS28305 002145fa57269dd598fa61ae4fdc8a18 727 SUPERFAMILY SSF55073 297 455 2.28E-33 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS16650 0d713f571b0db9b6ebdc7eeddef34190 317 SUPERFAMILY SSF161098 89 293 1.11E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS16650 0d713f571b0db9b6ebdc7eeddef34190 317 Gene3D G3DSA:1.10.3720.10 87 303 1.2E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS16650 0d713f571b0db9b6ebdc7eeddef34190 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 310 4.1E-27 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 Gene3D G3DSA:1.20.1560.10 49 365 4.0E-74 T 09-03-2017 UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 SUPERFAMILY SSF90123 48 367 1.23E-68 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 SMART SM00382 406 592 1.8E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 SUPERFAMILY SSF52540 371 615 3.03E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 Pfam PF00664 ABC transporter transmembrane region 61 328 1.2E-39 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 Pfam PF00005 ABC transporter 397 546 5.8E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS28465 896d1961d45ea12daca81e3c7e8ffde2 621 Gene3D G3DSA:3.40.50.300 380 607 3.7E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 521 2.2E-82 T 09-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 ProSitePatterns PS00296 Chaperonins cpn60 signature. 404 415 - T 09-03-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 Gene3D G3DSA:1.10.560.10 368 517 1.2E-37 T 09-03-2017 IPR027413 GroEL-like equatorial domain UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 27 53 9.0E-67 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 267 290 9.0E-67 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 349 374 9.0E-67 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 397 418 9.0E-67 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 83 110 9.0E-67 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 SUPERFAMILY SSF52029 184 375 7.33E-74 T 09-03-2017 IPR027409 GroEL-like apical domain UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 Gene3D G3DSA:3.50.7.10 186 367 7.5E-85 T 09-03-2017 IPR027409 GroEL-like apical domain UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 Gene3D G3DSA:1.10.560.10 3 185 1.4E-39 T 09-03-2017 IPR027413 GroEL-like equatorial domain UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 SUPERFAMILY SSF54849 137 203 3.66E-18 T 09-03-2017 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 525 1.6E-224 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 Hamap MF_00600 60 kDa chaperonin [groL]. 2 538 38.879 T 09-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 SUPERFAMILY SSF48592 3 136 4.95E-71 T 09-03-2017 UA74_RS28095 915c0af67299669116c47fa2fa56aff7 538 SUPERFAMILY SSF48592 407 522 4.95E-71 T 09-03-2017 UA74_RS30430 3c91e2feb220ed9d16942642d7d6b45f 331 Gene3D G3DSA:3.90.1530.10 64 163 4.3E-38 T 09-03-2017 UA74_RS30430 3c91e2feb220ed9d16942642d7d6b45f 331 Pfam PF02195 ParB-like nuclease domain 68 157 6.7E-26 T 09-03-2017 IPR003115 ParB/Sulfiredoxin UA74_RS30430 3c91e2feb220ed9d16942642d7d6b45f 331 SUPERFAMILY SSF110849 63 160 2.88E-29 T 09-03-2017 IPR003115 ParB/Sulfiredoxin UA74_RS30430 3c91e2feb220ed9d16942642d7d6b45f 331 SUPERFAMILY SSF109709 149 258 5.49E-32 T 09-03-2017 UA74_RS30430 3c91e2feb220ed9d16942642d7d6b45f 331 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 65 242 5.8E-61 T 09-03-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 UA74_RS30430 3c91e2feb220ed9d16942642d7d6b45f 331 SMART SM00470 67 157 5.2E-35 T 09-03-2017 IPR003115 ParB/Sulfiredoxin UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 Gene3D G3DSA:3.40.50.2300 2 151 1.1E-24 T 09-03-2017 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 SMART SM00448 1 120 7.4E-11 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 SUPERFAMILY SSF52172 2 136 1.28E-18 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 Gene3D G3DSA:1.10.10.10 152 211 1.8E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 195 1.8E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 Pfam PF00072 Response regulator receiver domain 3 108 6.5E-14 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 SMART SM00421 147 210 2.9E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 SUPERFAMILY SSF46894 136 195 2.38E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 4.9E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 4.9E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS01990 4c93db9cfa34e6131f3553638e864642 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 4.9E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17015 a5ccbbc1cbd69efefd3f7148ac3d9a4d 116 Pfam PF00550 Phosphopantetheine attachment site 45 91 1.2E-5 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17015 a5ccbbc1cbd69efefd3f7148ac3d9a4d 116 Gene3D G3DSA:1.10.1200.10 34 109 8.3E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17015 a5ccbbc1cbd69efefd3f7148ac3d9a4d 116 SUPERFAMILY SSF47336 34 110 5.63E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS12430 99047db57cf7cc049fa76a52253fde7d 338 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 4 276 8.5E-85 T 09-03-2017 IPR010119 Gluconeogenesis factor UA74_RS12430 99047db57cf7cc049fa76a52253fde7d 338 SUPERFAMILY SSF142338 2 309 7.72E-81 T 09-03-2017 UA74_RS12430 99047db57cf7cc049fa76a52253fde7d 338 Hamap MF_00973 Gluconeogenesis factor. 1 314 30.941 T 09-03-2017 IPR010119 Gluconeogenesis factor UA74_RS12430 99047db57cf7cc049fa76a52253fde7d 338 Pfam PF01933 Uncharacterised protein family UPF0052 4 270 4.3E-67 T 09-03-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 UA74_RS12430 99047db57cf7cc049fa76a52253fde7d 338 Gene3D G3DSA:3.40.50.10680 76 312 7.8E-43 T 09-03-2017 UA74_RS23905 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00710 232 254 1300.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS23905 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00710 154 176 1400.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS23905 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00710 130 152 40.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS23905 815edb9d1b1df67ec1a3a828a6ca79d6 329 Gene3D G3DSA:2.160.20.10 37 328 5.4E-86 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS23905 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00656 67 271 3.3E-37 T 09-03-2017 IPR002022 Pectate lyase/Amb allergen UA74_RS23905 815edb9d1b1df67ec1a3a828a6ca79d6 329 Pfam PF00544 Pectate lyase 106 265 2.3E-32 T 09-03-2017 IPR002022 Pectate lyase/Amb allergen UA74_RS23905 815edb9d1b1df67ec1a3a828a6ca79d6 329 SUPERFAMILY SSF51126 52 328 2.48E-70 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS09510 098da68e869c4016e7a5d38e7cf2145f 265 Pfam PF00196 Bacterial regulatory proteins, luxR family 212 258 1.7E-5 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS09510 098da68e869c4016e7a5d38e7cf2145f 265 SMART SM00421 201 258 0.0055 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS09510 098da68e869c4016e7a5d38e7cf2145f 265 Gene3D G3DSA:1.10.10.10 212 264 5.9E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09510 098da68e869c4016e7a5d38e7cf2145f 265 SUPERFAMILY SSF46894 211 264 2.82E-7 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS07440 ac8672b8b183f1c736eb2d625b63e159 666 Gene3D G3DSA:3.20.20.70 274 485 1.1E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS07440 ac8672b8b183f1c736eb2d625b63e159 666 SUPERFAMILY SSF51445 214 576 2.04E-64 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07440 ac8672b8b183f1c736eb2d625b63e159 666 Pfam PF01055 Glycosyl hydrolases family 31 206 660 6.9E-117 T 09-03-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 UA74_RS07440 ac8672b8b183f1c736eb2d625b63e159 666 SUPERFAMILY SSF74650 9 212 1.88E-29 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 UA74_RS07440 ac8672b8b183f1c736eb2d625b63e159 666 SUPERFAMILY SSF51011 577 657 1.15E-23 T 09-03-2017 UA74_RS06550 6bb1edda87d9712717f87d4558837c81 356 PIRSF PIRSF005739 7 324 1.3E-37 T 09-03-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_RS06550 6bb1edda87d9712717f87d4558837c81 356 SUPERFAMILY SSF53335 106 320 2.34E-45 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06550 6bb1edda87d9712717f87d4558837c81 356 Gene3D G3DSA:1.10.10.10 9 94 1.1E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06550 6bb1edda87d9712717f87d4558837c81 356 SUPERFAMILY SSF46785 14 86 7.26E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06550 6bb1edda87d9712717f87d4558837c81 356 Gene3D G3DSA:3.40.50.150 106 322 2.4E-55 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06550 6bb1edda87d9712717f87d4558837c81 356 Pfam PF00891 O-methyltransferase 106 319 3.1E-42 T 09-03-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_RS09695 6d946b49fb248ce2ca32872aed686883 606 Pfam PF00905 Penicillin binding protein transpeptidase domain 274 580 5.0E-80 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_RS09695 6d946b49fb248ce2ca32872aed686883 606 Gene3D G3DSA:3.40.710.10 256 586 1.2E-85 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS09695 6d946b49fb248ce2ca32872aed686883 606 SUPERFAMILY SSF56601 249 591 1.22E-89 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS09695 6d946b49fb248ce2ca32872aed686883 606 SUPERFAMILY SSF56519 66 248 4.05E-27 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UA74_RS09695 6d946b49fb248ce2ca32872aed686883 606 Pfam PF03717 Penicillin-binding Protein dimerisation domain 68 208 7.3E-9 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UA74_RS09695 6d946b49fb248ce2ca32872aed686883 606 Gene3D G3DSA:3.90.1310.10 150 255 4.7E-22 T 09-03-2017 UA74_RS01740 5f18e684dda52bd6aa1e76960ba732e1 364 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 361 2.2E-51 T 09-03-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UA74_RS01740 5f18e684dda52bd6aa1e76960ba732e1 364 Gene3D G3DSA:3.40.50.1980 182 242 1.0E-44 T 09-03-2017 UA74_RS01740 5f18e684dda52bd6aa1e76960ba732e1 364 Gene3D G3DSA:3.40.50.1980 36 139 1.0E-44 T 09-03-2017 UA74_RS01740 5f18e684dda52bd6aa1e76960ba732e1 364 SUPERFAMILY SSF53807 181 362 1.08E-61 T 09-03-2017 UA74_RS01740 5f18e684dda52bd6aa1e76960ba732e1 364 SUPERFAMILY SSF53807 40 147 1.08E-61 T 09-03-2017 UA74_RS01740 5f18e684dda52bd6aa1e76960ba732e1 364 Gene3D G3DSA:3.40.50.1980 262 362 4.3E-7 T 09-03-2017 UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 Pfam PF07729 FCD domain 100 220 9.6E-22 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 SUPERFAMILY SSF46785 13 75 3.93E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 71 7.2E-11 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 SUPERFAMILY SSF48008 97 226 2.09E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 Gene3D G3DSA:1.10.10.10 15 84 3.9E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 SMART SM00895 100 221 2.1E-20 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 SMART SM00345 13 71 7.3E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS13455 d98c33106c92a740fc0d89bd8c56e78b 232 Gene3D G3DSA:1.20.120.530 97 229 4.3E-24 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS15325 cbfc8107dbf9dd7a5e430054e0b447ca 432 SUPERFAMILY SSF88659 115 175 6.92E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15325 cbfc8107dbf9dd7a5e430054e0b447ca 432 Pfam PF04542 Sigma-70 region 2 22 85 2.4E-8 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15325 cbfc8107dbf9dd7a5e430054e0b447ca 432 Gene3D G3DSA:1.25.40.10 371 420 8.6E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS15325 cbfc8107dbf9dd7a5e430054e0b447ca 432 Pfam PF08281 Sigma-70, region 4 125 173 6.2E-7 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15325 cbfc8107dbf9dd7a5e430054e0b447ca 432 SUPERFAMILY SSF88946 16 83 3.22E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15325 cbfc8107dbf9dd7a5e430054e0b447ca 432 Gene3D G3DSA:1.10.1740.10 13 85 2.4E-9 T 09-03-2017 UA74_RS15325 cbfc8107dbf9dd7a5e430054e0b447ca 432 Gene3D G3DSA:1.10.10.10 116 175 4.0E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24090 10cbd52b42e897807e9fcb6d0d1ebcb8 233 SUPERFAMILY SSF53167 1 220 1.28E-40 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS24090 10cbd52b42e897807e9fcb6d0d1ebcb8 233 Gene3D G3DSA:3.40.50.1580 1 222 3.2E-46 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS24090 10cbd52b42e897807e9fcb6d0d1ebcb8 233 Pfam PF01048 Phosphorylase superfamily 2 203 6.6E-24 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS24450 1046b14d2108d8c7a6961098c5329e6c 259 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 4 258 40.648 T 09-03-2017 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS24450 1046b14d2108d8c7a6961098c5329e6c 259 Gene3D G3DSA:3.40.50.150 5 135 4.1E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24450 1046b14d2108d8c7a6961098c5329e6c 259 Gene3D G3DSA:3.40.50.150 172 191 4.1E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24450 1046b14d2108d8c7a6961098c5329e6c 259 Gene3D G3DSA:1.10.150.290 136 145 1.5E-22 T 09-03-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS24450 1046b14d2108d8c7a6961098c5329e6c 259 Gene3D G3DSA:1.10.150.290 192 238 1.5E-22 T 09-03-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS24450 1046b14d2108d8c7a6961098c5329e6c 259 Pfam PF13489 Methyltransferase domain 17 151 1.9E-16 T 09-03-2017 UA74_RS24450 1046b14d2108d8c7a6961098c5329e6c 259 SUPERFAMILY SSF53335 15 257 2.32E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 Gene3D G3DSA:1.10.287.130 234 303 8.5E-19 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 Gene3D G3DSA:3.30.565.10 333 462 3.5E-31 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 Pfam PF00672 HAMP domain 173 240 3.1E-15 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 SUPERFAMILY SSF158472 193 240 1.24E-7 T 09-03-2017 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 SUPERFAMILY SSF47384 227 307 3.34E-20 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 SMART SM00304 191 243 3.1E-12 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 456 1.2E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 SMART SM00387 348 458 5.7E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 SMART SM00388 244 307 1.6E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 SUPERFAMILY SSF55874 296 459 1.07E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 306 5.0E-17 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 1.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS21875 e8e240b9b89843ed208ba7f335ce2a60 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 1.2E-13 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS24980 dbfbf53519cd879b59dd1163187f8b7f 399 SUPERFAMILY SSF52540 4 282 3.91E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24980 dbfbf53519cd879b59dd1163187f8b7f 399 Pfam PF02374 Anion-transporting ATPase 2 304 9.5E-64 T 09-03-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_RS24980 dbfbf53519cd879b59dd1163187f8b7f 399 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 5 296 9.5E-56 T 09-03-2017 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 UA74_RS24980 dbfbf53519cd879b59dd1163187f8b7f 399 Gene3D G3DSA:3.40.50.300 3 281 7.3E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10020 d93cbfd91ffe2ba8ba60427940ee5c70 213 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 7 210 1.5E-65 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UA74_RS10020 d93cbfd91ffe2ba8ba60427940ee5c70 213 SUPERFAMILY SSF52317 7 210 1.26E-54 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS10020 d93cbfd91ffe2ba8ba60427940ee5c70 213 Gene3D G3DSA:3.40.50.880 6 211 6.2E-76 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS10020 d93cbfd91ffe2ba8ba60427940ee5c70 213 Pfam PF00117 Glutamine amidotransferase class-I 9 206 5.4E-17 T 09-03-2017 IPR017926 Glutamine amidotransferase UA74_RS10020 d93cbfd91ffe2ba8ba60427940ee5c70 213 PIRSF PIRSF000495 5 213 1.0E-63 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UA74_RS10020 d93cbfd91ffe2ba8ba60427940ee5c70 213 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 6 211 31.838 T 09-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 SMART SM00732 332 431 2.7E-37 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF53098 328 476 3.57E-50 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF09371 Tex-like protein N-terminal domain 9 192 2.7E-68 T 09-03-2017 IPR018974 Tex-like protein, N-terminal UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:1.10.150.310 506 637 1.3E-43 T 09-03-2017 IPR023097 Tex RuvX-like domain UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:1.10.3500.10 110 328 1.0E-103 T 09-03-2017 IPR023323 Tex-like domain UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:1.10.3500.10 458 505 1.0E-103 T 09-03-2017 IPR023323 Tex-like domain UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:2.40.50.140 650 727 5.8E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 SMART SM00316 656 727 4.3E-23 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:1.10.10.650 2 109 1.7E-44 T 09-03-2017 IPR023319 Tex-like protein, HTH domain UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:3.30.420.140 332 457 3.8E-49 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF00575 S1 RNA binding domain 658 727 2.5E-18 T 09-03-2017 IPR003029 S1 domain GO:0003676 UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF47781 477 565 1.22E-26 T 09-03-2017 IPR010994 RuvA domain 2-like UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF16921 Tex protein YqgF-like domain 333 458 1.8E-50 T 09-03-2017 IPR032639 Tex protein, YqgF-like domain UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF47781 567 638 1.58E-17 T 09-03-2017 IPR010994 RuvA domain 2-like UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF50249 645 731 6.56E-23 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF12836 Helix-hairpin-helix motif 498 562 5.0E-28 T 09-03-2017 UA74_RS23315 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF158832 3 327 2.62E-116 T 09-03-2017 UA74_RS21440 0e9956e5068230234653def4dfd7dd85 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 6.9E-17 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS21440 0e9956e5068230234653def4dfd7dd85 307 Gene3D G3DSA:1.10.10.10 6 86 2.9E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21440 0e9956e5068230234653def4dfd7dd85 307 SUPERFAMILY SSF53850 90 298 9.59E-33 T 09-03-2017 UA74_RS21440 0e9956e5068230234653def4dfd7dd85 307 Gene3D G3DSA:3.40.190.10 183 262 3.5E-22 T 09-03-2017 UA74_RS21440 0e9956e5068230234653def4dfd7dd85 307 Pfam PF03466 LysR substrate binding domain 89 291 1.5E-34 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS21440 0e9956e5068230234653def4dfd7dd85 307 Gene3D G3DSA:3.40.190.10 89 182 2.7E-21 T 09-03-2017 UA74_RS21440 0e9956e5068230234653def4dfd7dd85 307 SUPERFAMILY SSF46785 2 112 2.18E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04210 8cae01cfdcb6bc09ac1de19f07c66809 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 248 4.7E-50 T 09-03-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 UA74_RS04210 8cae01cfdcb6bc09ac1de19f07c66809 387 Gene3D G3DSA:3.60.21.10 1 269 7.4E-72 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS04210 8cae01cfdcb6bc09ac1de19f07c66809 387 SUPERFAMILY SSF56300 1 303 1.02E-53 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS04210 8cae01cfdcb6bc09ac1de19f07c66809 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 271 325 1.1E-6 T 09-03-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain UA74_RS04210 8cae01cfdcb6bc09ac1de19f07c66809 387 Pfam PF00149 Calcineurin-like phosphoesterase 1 222 5.2E-13 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS05770 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 395 3.0E-127 T 09-03-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_RS05770 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 Gene3D G3DSA:3.40.50.2000 233 376 3.3E-30 T 09-03-2017 UA74_RS05770 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 SUPERFAMILY SSF53756 1 393 4.4E-75 T 09-03-2017 UA74_RS05770 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 228 366 1.8E-12 T 09-03-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 UA74_RS05770 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 Gene3D G3DSA:3.40.50.2000 5 232 5.9E-13 T 09-03-2017 UA74_RS08650 998b7ec26c53c900b30847a0501c7501 211 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 09-03-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS08650 998b7ec26c53c900b30847a0501c7501 211 SUPERFAMILY SSF51569 6 208 1.7E-64 T 09-03-2017 UA74_RS08650 998b7ec26c53c900b30847a0501c7501 211 Gene3D G3DSA:3.20.20.70 7 207 2.6E-72 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS08650 998b7ec26c53c900b30847a0501c7501 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 207 3.7E-75 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS08650 998b7ec26c53c900b30847a0501c7501 211 Pfam PF01081 KDPG and KHG aldolase 11 201 4.1E-67 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS08650 998b7ec26c53c900b30847a0501c7501 211 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 09-03-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS06150 e27a3799c1909df0a6cd69f126e7bc93 166 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 41 4.4E-8 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS06150 e27a3799c1909df0a6cd69f126e7bc93 166 SUPERFAMILY SSF143120 5 44 8.63E-6 T 09-03-2017 UA74_RS06150 e27a3799c1909df0a6cd69f126e7bc93 166 Gene3D G3DSA:3.40.1620.10 8 41 2.6E-4 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS11475 4253a05f1cd3c2269eb5aaabb00c4aa7 188 Pfam PF13411 MerR HTH family regulatory protein 30 99 2.7E-15 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS11475 4253a05f1cd3c2269eb5aaabb00c4aa7 188 SUPERFAMILY SSF46955 33 118 3.3E-15 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS11475 4253a05f1cd3c2269eb5aaabb00c4aa7 188 Gene3D G3DSA:1.10.1660.10 35 108 2.8E-13 T 09-03-2017 UA74_RS11475 4253a05f1cd3c2269eb5aaabb00c4aa7 188 SMART SM00422 30 102 6.1E-19 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 SMART SM00267 427 600 3.9E-24 T 09-03-2017 IPR000160 GGDEF domain UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 SUPERFAMILY SSF141868 614 860 1.96E-84 T 09-03-2017 IPR001633 EAL domain UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 SUPERFAMILY SSF55781 294 436 1.74E-12 T 09-03-2017 IPR029016 GAF domain-like UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 Gene3D G3DSA:3.20.20.450 610 859 1.8E-91 T 09-03-2017 IPR001633 EAL domain UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 SMART SM00065 290 435 2.0E-9 T 09-03-2017 IPR003018 GAF domain GO:0005515 UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 SUPERFAMILY SSF55073 443 591 1.96E-22 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 Gene3D G3DSA:3.30.70.270 439 602 1.1E-27 T 09-03-2017 UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 SMART SM00052 607 852 4.8E-106 T 09-03-2017 IPR001633 EAL domain UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 Pfam PF00990 Diguanylate cyclase, GGDEF domain 438 589 6.7E-21 T 09-03-2017 IPR000160 GGDEF domain UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 Pfam PF13492 GAF domain 295 427 5.5E-7 T 09-03-2017 IPR003018 GAF domain GO:0005515 UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 Pfam PF00563 EAL domain 614 847 5.5E-69 T 09-03-2017 IPR001633 EAL domain UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 435 589 2.6E-14 T 09-03-2017 IPR000160 GGDEF domain UA74_RS02780 585cf2b441e4dfce933639b7cde6a1bd 877 Gene3D G3DSA:3.30.450.40 290 437 4.9E-12 T 09-03-2017 IPR029016 GAF domain-like UA74_RS26610 a7594e7aab999fbcfea0caa03392f9e0 168 Pfam PF00583 Acetyltransferase (GNAT) family 66 142 8.7E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS26610 a7594e7aab999fbcfea0caa03392f9e0 168 SUPERFAMILY SSF55729 4 152 2.57E-25 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS26610 a7594e7aab999fbcfea0caa03392f9e0 168 Gene3D G3DSA:3.40.630.30 4 156 2.9E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15060 876eb71e911815b038e421a8b3563f2e 360 Gene3D G3DSA:3.50.50.60 4 96 1.6E-14 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15060 876eb71e911815b038e421a8b3563f2e 360 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 288 5.7E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15060 876eb71e911815b038e421a8b3563f2e 360 SUPERFAMILY SSF51905 5 305 6.05E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15060 876eb71e911815b038e421a8b3563f2e 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 5.2E-8 T 09-03-2017 UA74_RS15060 876eb71e911815b038e421a8b3563f2e 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 91 109 5.2E-8 T 09-03-2017 UA74_RS15060 876eb71e911815b038e421a8b3563f2e 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.2E-8 T 09-03-2017 UA74_RS15060 876eb71e911815b038e421a8b3563f2e 360 Gene3D G3DSA:3.50.50.60 97 296 3.1E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS06600 e69849aa98f72b359a9eb9c9375cf326 254 Pfam PF00975 Thioesterase domain 23 241 1.0E-42 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS06600 e69849aa98f72b359a9eb9c9375cf326 254 Gene3D G3DSA:3.40.50.1820 18 240 3.9E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06600 e69849aa98f72b359a9eb9c9375cf326 254 SUPERFAMILY SSF53474 12 245 1.79E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06600 e69849aa98f72b359a9eb9c9375cf326 254 SMART SM00824 Thioesterase 25 208 5.8E-4 T 09-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 Gene3D G3DSA:3.50.50.60 281 365 4.1E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 Gene3D G3DSA:3.50.50.60 3 173 4.1E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 SUPERFAMILY SSF51905 3 168 2.89E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 SUPERFAMILY SSF51905 280 370 2.89E-57 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 8.9E-43 T 09-03-2017 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 8.9E-43 T 09-03-2017 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 8.9E-43 T 09-03-2017 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 8.9E-43 T 09-03-2017 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 8.9E-43 T 09-03-2017 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 8.9E-43 T 09-03-2017 UA74_RS05930 0b1d8ae84bda8691f8f765b2977ebe86 528 Pfam PF01494 FAD binding domain 3 358 1.3E-66 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS01985 326e182d41ecc38bc49f27ea6f1ba337 436 SUPERFAMILY SSF55874 345 433 5.16E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS01985 326e182d41ecc38bc49f27ea6f1ba337 436 Gene3D G3DSA:3.30.565.10 353 434 7.4E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS01985 326e182d41ecc38bc49f27ea6f1ba337 436 Pfam PF13796 Putative sensor 22 193 1.9E-18 T 09-03-2017 IPR025828 Putative sensor domain UA74_RS01985 326e182d41ecc38bc49f27ea6f1ba337 436 SMART SM00387 346 436 2.8E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS01985 326e182d41ecc38bc49f27ea6f1ba337 436 Pfam PF07730 Histidine kinase 222 287 5.0E-14 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS18915 c2fb228f9cbbe988e63aa0525c5c02e4 373 SUPERFAMILY SSF103481 45 141 8.37E-15 T 09-03-2017 UA74_RS18915 c2fb228f9cbbe988e63aa0525c5c02e4 373 Pfam PF00892 EamA-like transporter family 152 293 3.9E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS18915 c2fb228f9cbbe988e63aa0525c5c02e4 373 Pfam PF00892 EamA-like transporter family 11 141 1.2E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS18915 c2fb228f9cbbe988e63aa0525c5c02e4 373 SUPERFAMILY SSF103481 220 296 1.16E-9 T 09-03-2017 UA74_RS27415 df943144dae5a8d4fc5f1d4f90ed931b 619 Pfam PF00069 Protein kinase domain 6 211 2.9E-45 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS27415 df943144dae5a8d4fc5f1d4f90ed931b 619 SMART SM00220 6 265 1.3E-58 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS27415 df943144dae5a8d4fc5f1d4f90ed931b 619 Gene3D G3DSA:1.10.510.10 78 258 2.3E-43 T 09-03-2017 UA74_RS27415 df943144dae5a8d4fc5f1d4f90ed931b 619 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 35 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS27415 df943144dae5a8d4fc5f1d4f90ed931b 619 Gene3D G3DSA:3.30.200.20 2 77 3.0E-21 T 09-03-2017 UA74_RS27415 df943144dae5a8d4fc5f1d4f90ed931b 619 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS27415 df943144dae5a8d4fc5f1d4f90ed931b 619 SUPERFAMILY SSF56112 2 263 2.43E-66 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS23480 f935fb12ba501794d8b2bfccb06e13ce 295 Gene3D G3DSA:2.40.30.10 4 131 5.1E-35 T 09-03-2017 UA74_RS23480 f935fb12ba501794d8b2bfccb06e13ce 295 Pfam PF08021 Siderophore-interacting FAD-binding domain 11 132 2.1E-34 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting UA74_RS23480 f935fb12ba501794d8b2bfccb06e13ce 295 SUPERFAMILY SSF63380 8 136 1.04E-12 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS23480 f935fb12ba501794d8b2bfccb06e13ce 295 Gene3D G3DSA:3.40.50.80 145 272 2.8E-42 T 09-03-2017 UA74_RS23480 f935fb12ba501794d8b2bfccb06e13ce 295 Pfam PF04954 Siderophore-interacting protein 147 264 1.7E-36 T 09-03-2017 IPR007037 Siderophore-interacting protein UA74_RS12355 22416c6dcee5755ae9d0602a4360e6cb 670 SUPERFAMILY SSF52540 185 262 1.33E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12355 22416c6dcee5755ae9d0602a4360e6cb 670 Hamap MF_00983 Probable primosomal protein N' [priA]. 26 669 20.063 T 09-03-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 UA74_RS12355 22416c6dcee5755ae9d0602a4360e6cb 670 Gene3D G3DSA:3.40.50.300 183 268 7.3E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 Gene3D G3DSA:2.40.180.10 3 356 3.4E-171 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 09-03-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 Pfam PF00199 Catalase 8 385 9.3E-181 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 Pfam PF06628 Catalase-related immune-responsive 418 479 1.4E-16 T 09-03-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 SMART SM01060 8 389 2.8E-273 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 PIRSF PIRSF038928 1 483 1.6E-229 T 09-03-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 SUPERFAMILY SSF56634 5 481 2.62E-197 T 09-03-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 09-03-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 104 121 1.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 123 141 1.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 320 346 1.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 288 315 1.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 21 44 1.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS01085 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 83 101 1.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS15850 52a88a53bcc326e52c10d4fa5c7fac29 160 Gene3D G3DSA:3.90.79.10 20 150 3.9E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS15850 52a88a53bcc326e52c10d4fa5c7fac29 160 Pfam PF00293 NUDIX domain 22 135 5.0E-17 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS15850 52a88a53bcc326e52c10d4fa5c7fac29 160 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS15850 52a88a53bcc326e52c10d4fa5c7fac29 160 SUPERFAMILY SSF55811 19 149 2.37E-27 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 SUPERFAMILY SSF50104 1 99 2.37E-29 T 09-03-2017 IPR008991 Translation protein SH3-like domain UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 104 6.2E-36 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 Pfam PF00467 KOW motif 5 36 3.8E-8 T 09-03-2017 IPR005824 KOW UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 Gene3D G3DSA:2.30.30.30 1 92 7.3E-27 T 09-03-2017 IPR014722 Ribosomal protein L2 domain 2 UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 104 1.7E-23 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 98 20.703 T 09-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 SMART SM00739 2 29 1.7E-4 T 09-03-2017 IPR005824 KOW UA74_RS02985 36ebb32901aa50e8b7cc8fddb6755740 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 09-03-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02655 12a718947081a113aaf31803fe2e4caa 224 SMART SM00862 145 217 3.0E-21 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS02655 12a718947081a113aaf31803fe2e4caa 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 216 4.3E-20 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS02655 12a718947081a113aaf31803fe2e4caa 224 SMART SM00448 1 112 7.0E-29 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS02655 12a718947081a113aaf31803fe2e4caa 224 Gene3D G3DSA:3.40.50.2300 1 120 5.1E-31 T 09-03-2017 UA74_RS02655 12a718947081a113aaf31803fe2e4caa 224 Pfam PF00072 Response regulator receiver domain 3 112 1.6E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS02655 12a718947081a113aaf31803fe2e4caa 224 SUPERFAMILY SSF52172 1 175 2.26E-33 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS02655 12a718947081a113aaf31803fe2e4caa 224 Gene3D G3DSA:1.10.10.10 122 220 2.2E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19775 c5b4ba9aab5747c4f328332f7ce12c9b 425 SUPERFAMILY SSF141130 147 425 1.05E-73 T 09-03-2017 UA74_RS19775 c5b4ba9aab5747c4f328332f7ce12c9b 425 SUPERFAMILY SSF141130 77 116 1.05E-73 T 09-03-2017 UA74_RS19775 c5b4ba9aab5747c4f328332f7ce12c9b 425 Gene3D G3DSA:3.10.28.20 341 424 2.2E-21 T 09-03-2017 UA74_RS19775 c5b4ba9aab5747c4f328332f7ce12c9b 425 Gene3D G3DSA:2.60.120.580 245 327 6.5E-53 T 09-03-2017 UA74_RS19775 c5b4ba9aab5747c4f328332f7ce12c9b 425 Gene3D G3DSA:2.60.120.580 71 177 6.5E-53 T 09-03-2017 UA74_RS19775 c5b4ba9aab5747c4f328332f7ce12c9b 425 Pfam PF03069 Acetamidase/Formamidase family 265 410 3.2E-18 T 09-03-2017 IPR004304 Acetamidase/Formamidase GO:0016811 UA74_RS19775 c5b4ba9aab5747c4f328332f7ce12c9b 425 Pfam PF03069 Acetamidase/Formamidase family 152 256 1.7E-5 T 09-03-2017 IPR004304 Acetamidase/Formamidase GO:0016811 UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 269 2.5E-83 T 09-03-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 PIRSF PIRSF000331 1 482 1.1E-99 T 09-03-2017 IPR004925 HpaB/PvcC/4-BUDH UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 Gene3D G3DSA:2.40.110.10 148 262 1.8E-41 T 09-03-2017 UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 280 475 4.7E-55 T 09-03-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 SUPERFAMILY SSF56645 1 271 1.49E-72 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 SUPERFAMILY SSF47203 261 476 4.38E-63 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 Gene3D G3DSA:1.10.3140.10 1 142 1.2E-38 T 09-03-2017 UA74_RS20560 70a4106e1aa53f7fee02172287eb9784 488 Gene3D G3DSA:1.20.140.10 263 477 1.2E-51 T 09-03-2017 UA74_RS16110 490aac82e6d373177b53c0d791fb33be 227 Gene3D G3DSA:3.40.50.720 7 201 1.0E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16110 490aac82e6d373177b53c0d791fb33be 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.2E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16110 490aac82e6d373177b53c0d791fb33be 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.2E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16110 490aac82e6d373177b53c0d791fb33be 227 SUPERFAMILY SSF51735 8 184 5.27E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16110 490aac82e6d373177b53c0d791fb33be 227 Pfam PF00106 short chain dehydrogenase 9 177 1.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 SUPERFAMILY SSF48264 16 402 8.25E-100 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 Pfam PF00067 Cytochrome P450 182 372 9.1E-24 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00385 P450 superfamily signature 239 256 4.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00385 P450 superfamily signature 342 351 4.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00385 P450 superfamily signature 351 362 4.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00385 P450 superfamily signature 274 285 4.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 Gene3D G3DSA:1.10.630.10 10 402 4.9E-129 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 342 351 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 139 155 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 194 216 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 293 320 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 274 285 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 321 336 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 156 171 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 351 362 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 PRINTS PR00359 B-class P450 signature 92 103 9.4E-58 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14890 2bf296f9ab04ee8089417f05810973f8 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS01540 c3f955ca3dc7e05d19b17472fe2846cc 161 Pfam PF11377 Protein of unknown function (DUF3180) 9 143 2.8E-34 T 09-03-2017 IPR021517 Protein of unknown function DUF3180 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 SUPERFAMILY SSF51905 2 316 2.27E-40 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 321 7.9E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 09-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 2.9E-40 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 2.9E-40 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 2.9E-40 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.9E-40 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.9E-40 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 2.9E-40 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 2.9E-40 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PIRSF PIRSF000350 1 449 2.2E-83 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 453 1.9E-26 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 Gene3D G3DSA:3.50.50.60 3 145 3.6E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 Gene3D G3DSA:3.50.50.60 277 333 3.6E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 SUPERFAMILY SSF55424 342 456 1.34E-31 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 Gene3D G3DSA:3.30.390.30 334 456 1.5E-36 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 Gene3D G3DSA:3.50.50.60 146 276 3.4E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 9.2E-23 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 9.2E-23 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 9.2E-23 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 9.2E-23 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.2E-23 T 09-03-2017 UA74_RS09160 436ce5a3235e6e0672b473684af6b775 462 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 2 458 3.6E-197 T 09-03-2017 IPR017817 Mycothione reductase MetaCyc: PWY-6421 UA74_RS03120 085f8e577998de0f29c93cc32db62de9 126 Gene3D G3DSA:1.10.8.50 1 72 1.4E-30 T 09-03-2017 UA74_RS03120 085f8e577998de0f29c93cc32db62de9 126 Gene3D G3DSA:4.10.910.10 73 125 3.3E-25 T 09-03-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03120 085f8e577998de0f29c93cc32db62de9 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.798 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03120 085f8e577998de0f29c93cc32db62de9 126 PIRSF PIRSF002134 1 125 7.7E-44 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03120 085f8e577998de0f29c93cc32db62de9 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 2.9E-32 T 09-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03120 085f8e577998de0f29c93cc32db62de9 126 SUPERFAMILY SSF46946 2 124 6.93E-46 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_RS03120 085f8e577998de0f29c93cc32db62de9 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 2.5E-51 T 09-03-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS11090 18054f88d3d7cc68628fdf6974b66437 155 SUPERFAMILY SSF55961 3 150 1.28E-33 T 09-03-2017 UA74_RS11090 18054f88d3d7cc68628fdf6974b66437 155 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 132 6.1E-12 T 09-03-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain UA74_RS11090 18054f88d3d7cc68628fdf6974b66437 155 Gene3D G3DSA:3.30.530.20 4 147 4.3E-16 T 09-03-2017 IPR023393 START-like domain UA74_RS28280 368414908ad2959ad172d07b42f61e10 138 Gene3D G3DSA:2.30.110.10 6 137 4.7E-36 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS28280 368414908ad2959ad172d07b42f61e10 138 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 97 2.0E-12 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS28280 368414908ad2959ad172d07b42f61e10 138 SUPERFAMILY SSF50475 3 136 4.68E-27 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS28280 368414908ad2959ad172d07b42f61e10 138 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 8 135 5.0E-46 T 09-03-2017 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 SMART SM00421 826 883 2.9E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 SUPERFAMILY SSF46894 817 883 1.67E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 SUPERFAMILY SSF52540 15 212 7.64E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 SUPERFAMILY SSF48452 623 792 2.03E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 Gene3D G3DSA:3.40.50.300 23 151 6.5E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 Pfam PF00196 Bacterial regulatory proteins, luxR family 828 880 9.8E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 871 8.5E-5 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 843 859 8.5E-5 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 829 843 8.5E-5 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 Gene3D G3DSA:1.10.10.10 821 883 4.2E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16580 aa1f437823a043c4d7d9d0852a1fee0b 905 Gene3D G3DSA:1.25.40.10 566 781 3.7E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Pfam PF00226 DnaJ domain 4 65 4.4E-23 T 09-03-2017 IPR001623 DnaJ domain UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF57938 133 213 2.22E-17 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:2.60.260.20 202 255 3.8E-16 T 09-03-2017 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:2.60.260.20 114 135 3.8E-16 T 09-03-2017 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:2.60.260.20 259 341 3.0E-19 T 09-03-2017 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 383 36.605 T 09-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:1.10.287.110 3 102 2.0E-28 T 09-03-2017 IPR001623 DnaJ domain UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF49493 262 351 1.7E-19 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF49493 189 266 6.15E-17 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF49493 114 137 6.15E-17 T 09-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:2.10.230.10 136 201 1.7E-18 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF46565 3 102 4.97E-30 T 09-03-2017 IPR001623 DnaJ domain UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 SMART SM00271 3 60 5.3E-28 T 09-03-2017 IPR001623 DnaJ domain UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Pfam PF01556 DnaJ C terminal domain 121 340 4.0E-36 T 09-03-2017 IPR002939 Chaperone DnaJ, C-terminal UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 Pfam PF00684 DnaJ central domain 146 210 4.3E-12 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 6 24 1.0E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 60 79 1.0E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 40 60 1.0E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS24615 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 24 39 1.0E-21 T 09-03-2017 IPR001623 DnaJ domain UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 SUPERFAMILY SSF51735 103 282 2.12E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 281 1.4E-44 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 Gene3D G3DSA:3.40.50.720 112 282 6.9E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 Gene3D G3DSA:3.40.50.720 12 111 8.7E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 33 310 7.9E-28 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 SUPERFAMILY SSF52283 12 137 3.78E-32 T 09-03-2017 UA74_RS00945 c5f86be3fdb5db95496e36f2a554180c 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS11875 0254593f314671191c0f95ec404d222f 149 SUPERFAMILY SSF46785 18 147 6.54E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11875 0254593f314671191c0f95ec404d222f 149 SMART SM00347 39 136 2.2E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS11875 0254593f314671191c0f95ec404d222f 149 Gene3D G3DSA:1.10.10.10 20 147 1.7E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11875 0254593f314671191c0f95ec404d222f 149 Pfam PF01047 MarR family 58 101 7.1E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS11875 0254593f314671191c0f95ec404d222f 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 2.7E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS11875 0254593f314671191c0f95ec404d222f 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 2.7E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS11875 0254593f314671191c0f95ec404d222f 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 2.7E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 Gene3D G3DSA:1.10.10.10 18 77 5.2E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 SUPERFAMILY SSF46785 11 79 7.35E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 PRINTS PR01467 Bacterial arginine repressor signature 30 43 7.0E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 PRINTS PR01467 Bacterial arginine repressor signature 133 148 7.0E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 PRINTS PR01467 Bacterial arginine repressor signature 46 61 7.0E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 PRINTS PR01467 Bacterial arginine repressor signature 103 116 7.0E-26 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 TIGRFAM TIGR01529 argR_whole: arginine repressor 14 163 1.2E-46 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 103 160 6.0E-19 T 09-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 Pfam PF01316 Arginine repressor, DNA binding domain 12 79 1.5E-22 T 09-03-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 Gene3D G3DSA:3.30.1360.40 89 163 1.7E-27 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 Hamap MF_00173 Arginine repressor [argR]. 1 166 59.652 T 09-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 SUPERFAMILY SSF55252 95 162 4.71E-18 T 09-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UA74_RS21670 39404eaf2358e5f9b71d1b260a59258b 166 Pfam PF02863 Arginine repressor, C-terminal domain 95 160 2.1E-24 T 09-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UA74_RS05800 c1acbbc6886dafe181f2dc3f30b3bac3 100 SUPERFAMILY SSF47336 18 90 2.62E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05800 c1acbbc6886dafe181f2dc3f30b3bac3 100 Pfam PF00550 Phosphopantetheine attachment site 19 86 2.3E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05800 c1acbbc6886dafe181f2dc3f30b3bac3 100 Gene3D G3DSA:1.10.1200.10 18 91 1.2E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS30200 ad63fa940338d12ba5a1494fc37082bd 319 Gene3D G3DSA:3.40.50.300 4 230 8.8E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30200 ad63fa940338d12ba5a1494fc37082bd 319 SMART SM00382 34 217 3.9E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS30200 ad63fa940338d12ba5a1494fc37082bd 319 SUPERFAMILY SSF52540 8 230 1.05E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30200 ad63fa940338d12ba5a1494fc37082bd 319 Pfam PF00005 ABC transporter 25 168 3.6E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS30200 ad63fa940338d12ba5a1494fc37082bd 319 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 308 5.2E-94 T 09-03-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_RS30200 ad63fa940338d12ba5a1494fc37082bd 319 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS02730 68970003ea877a212a25b1ff287d6eea 361 SUPERFAMILY SSF101478 23 248 6.93E-41 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 UA74_RS02730 68970003ea877a212a25b1ff287d6eea 361 SUPERFAMILY SSF101478 283 350 6.93E-41 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 UA74_RS02730 68970003ea877a212a25b1ff287d6eea 361 Pfam PF03747 ADP-ribosylglycohydrolase 30 337 4.2E-48 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 Gene3D G3DSA:3.40.50.2300 2 127 2.9E-34 T 09-03-2017 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 SUPERFAMILY SSF46894 152 223 5.44E-23 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 6.3E-21 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 SMART SM00421 160 217 9.6E-26 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 Gene3D G3DSA:1.10.10.10 128 224 1.9E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 SUPERFAMILY SSF52172 4 137 8.11E-31 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 5.6E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 5.6E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 5.6E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 Pfam PF00072 Response regulator receiver domain 7 119 5.1E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS05330 e1598b6ede9f4e042bcde4139705431d 227 SMART SM00448 5 120 1.0E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS16825 d2fd33d30a82b033a96b5e71df422892 198 Gene3D G3DSA:2.60.120.10 91 178 6.8E-15 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS16825 d2fd33d30a82b033a96b5e71df422892 198 Gene3D G3DSA:1.10.260.40 16 84 3.2E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16825 d2fd33d30a82b033a96b5e71df422892 198 SMART SM00530 18 73 2.4E-17 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS16825 d2fd33d30a82b033a96b5e71df422892 198 SUPERFAMILY SSF51182 24 181 4.19E-16 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS16825 d2fd33d30a82b033a96b5e71df422892 198 Pfam PF01381 Helix-turn-helix 19 73 1.3E-15 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS16825 d2fd33d30a82b033a96b5e71df422892 198 SUPERFAMILY SSF47413 14 79 9.57E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16825 d2fd33d30a82b033a96b5e71df422892 198 Pfam PF07883 Cupin domain 111 177 2.6E-9 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS17325 0b084f99f89e8f9e716ccf022335da56 402 Gene3D G3DSA:3.90.1150.10 246 368 8.7E-41 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS17325 0b084f99f89e8f9e716ccf022335da56 402 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 363 1.6E-125 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_RS17325 0b084f99f89e8f9e716ccf022335da56 402 Gene3D G3DSA:3.40.640.10 14 244 3.1E-81 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS17325 0b084f99f89e8f9e716ccf022335da56 402 PIRSF PIRSF000390 6 370 2.2E-112 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_RS17325 0b084f99f89e8f9e716ccf022335da56 402 SUPERFAMILY SSF53383 15 366 1.34E-113 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 SMART SM00881 108 209 6.0E-17 T 09-03-2017 IPR003781 CoA-binding GO:0048037 UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 Gene3D G3DSA:3.40.50.720 107 242 1.9E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 Pfam PF02629 CoA binding domain 111 208 5.6E-19 T 09-03-2017 IPR003781 CoA-binding GO:0048037 UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 Pfam PF06971 Putative DNA-binding protein N-terminus 35 82 5.1E-18 T 09-03-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 SUPERFAMILY SSF51735 113 233 2.03E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 SUPERFAMILY SSF46785 36 108 2.45E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 Gene3D G3DSA:1.10.10.10 34 104 6.0E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02295 4bfeff7e5cd27ec9b183249fcca00863 267 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 30 238 34.817 T 09-03-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 UA74_RS20710 19304c5ccb4028de127ec83480e00a6f 238 Pfam PF02754 Cysteine-rich domain 122 206 1.8E-15 T 09-03-2017 IPR004017 Cysteine-rich domain UA74_RS20710 19304c5ccb4028de127ec83480e00a6f 238 Pfam PF02754 Cysteine-rich domain 1 81 7.8E-15 T 09-03-2017 IPR004017 Cysteine-rich domain UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 Gene3D G3DSA:1.10.10.10 14 89 5.5E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 SMART SM01043 95 237 9.0E-50 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF48452 92 261 5.44E-33 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 Gene3D G3DSA:1.25.40.10 780 979 2.2E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF52540 252 541 4.66E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF46894 3 88 9.92E-12 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 SMART SM00862 16 88 1.5E-8 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 87 8.7E-7 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF48452 809 974 8.93E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 Gene3D G3DSA:3.40.50.300 262 310 3.0E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 PRINTS PR00364 Disease resistance protein signature 364 378 1.1E-7 T 09-03-2017 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 PRINTS PR00364 Disease resistance protein signature 475 489 1.1E-7 T 09-03-2017 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 PRINTS PR00364 Disease resistance protein signature 287 302 1.1E-7 T 09-03-2017 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 Pfam PF00931 NB-ARC domain 269 404 1.4E-9 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS19560 7a6f1d00b4686b0686e9161bcd41d358 1056 Pfam PF03704 Bacterial transcriptional activator domain 95 237 1.2E-37 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Gene3D G3DSA:3.30.54.20 124 201 1.3E-6 T 09-03-2017 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 64 657 2.0E-190 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 SUPERFAMILY SSF52954 558 665 1.48E-28 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 PRINTS PR01047 Threonyl-tRNA synthetase signature 563 575 1.9E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 549 1.9E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 PRINTS PR01047 Threonyl-tRNA synthetase signature 390 413 1.9E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 PRINTS PR01047 Threonyl-tRNA synthetase signature 493 521 1.9E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 PRINTS PR01047 Threonyl-tRNA synthetase signature 357 385 1.9E-51 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Gene3D G3DSA:3.30.930.10 256 559 4.5E-105 T 09-03-2017 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 SMART SM00863 177 233 4.4E-19 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 SUPERFAMILY SSF55186 56 254 7.85E-49 T 09-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Gene3D G3DSA:3.40.50.800 560 664 1.0E-28 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Gene3D G3DSA:3.30.980.10 202 238 2.0E-41 T 09-03-2017 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Gene3D G3DSA:3.30.980.10 58 121 2.0E-41 T 09-03-2017 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 SUPERFAMILY SSF55681 257 554 1.13E-93 T 09-03-2017 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 186 233 1.2E-12 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 352 558 4.1E-36 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Pfam PF03129 Anticodon binding domain 570 658 1.9E-16 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS10825 b0e821322401c013eadf55fe1e6cf876 680 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 58 663 33.318 T 09-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 182 6.2E-4 T 09-03-2017 UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 Pfam PF00106 short chain dehydrogenase 3 187 1.1E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 SUPERFAMILY SSF51735 3 250 3.23E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.5E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.5E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.5E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.5E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.5E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 Gene3D G3DSA:3.40.50.720 3 220 1.6E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 4.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 4.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29790 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PIRSF PIRSF000126 1 257 3.1E-70 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS26850 b405d9591d6180afa2900c3a61a8429a 381 Gene3D G3DSA:3.20.20.70 16 346 6.7E-31 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS26850 b405d9591d6180afa2900c3a61a8429a 381 Pfam PF04055 Radical SAM superfamily 30 184 2.1E-10 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS26850 b405d9591d6180afa2900c3a61a8429a 381 SUPERFAMILY SSF102114 17 336 1.16E-27 T 09-03-2017 UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 SUPERFAMILY SSF52518 8 178 6.34E-40 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 Gene3D G3DSA:3.40.50.1220 182 334 5.5E-35 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 172 1.8E-43 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 SUPERFAMILY SSF52467 155 333 2.36E-30 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 Gene3D G3DSA:3.40.50.970 362 540 2.1E-41 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 537 8.4E-27 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 SUPERFAMILY SSF52518 365 540 1.22E-40 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 325 7.6E-22 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UA74_RS07685 2bc0049a2094cc05709f5078b3f38671 541 Gene3D G3DSA:3.40.50.970 4 176 2.0E-47 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS03770 6281a8d6f6b77e3f330836c159eb63b7 152 Pfam PF13160 Protein of unknown function (DUF3995) 10 138 8.1E-17 T 09-03-2017 IPR025058 Protein of unknown function DUF3995 UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 Pfam PF00717 Peptidase S24-like 160 223 2.2E-15 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 SUPERFAMILY SSF46785 33 99 1.23E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 Hamap MF_00015 LexA repressor [lexA]. 33 241 33.936 T 09-03-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 Pfam PF01726 LexA DNA binding domain 32 95 4.1E-28 T 09-03-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 Gene3D G3DSA:2.10.109.10 122 241 2.3E-44 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 Gene3D G3DSA:1.10.10.10 32 99 5.4E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 SUPERFAMILY SSF51306 120 239 4.88E-36 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 168 179 2.1E-11 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 196 208 2.1E-11 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 157 167 2.1E-11 T 09-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UA74_RS08735 42764bfcac4fc90c86247cd524e94e3a 241 TIGRFAM TIGR00498 lexA: repressor LexA 32 240 4.7E-76 T 09-03-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 Gene3D G3DSA:1.20.5.220 115 127 4.3E-4 T 09-03-2017 IPR029027 Single alpha-helix domain Reactome: R-HSA-611105 UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 SUPERFAMILY SSF81330 10 124 3.27E-27 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 130 1.5E-30 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 09-03-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 127 2.5E-38 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 80 88 4.6E-9 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 4.6E-9 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 UA74_RS03245 ad25fd47e7b2f61c5d367f435e47f2d1 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 90 99 4.6E-9 T 09-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 UA74_RS27070 3f010780ba97c2c2744a56799cc78505 287 SUPERFAMILY SSF55681 27 223 3.64E-42 T 09-03-2017 UA74_RS27070 3f010780ba97c2c2744a56799cc78505 287 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 143 1.2E-9 T 09-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 UA74_RS27070 3f010780ba97c2c2744a56799cc78505 287 SUPERFAMILY SSF50037 239 283 1.92E-7 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal UA74_RS27070 3f010780ba97c2c2744a56799cc78505 287 Pfam PF02237 Biotin protein ligase C terminal domain 236 283 1.1E-10 T 09-03-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS27070 3f010780ba97c2c2744a56799cc78505 287 Gene3D G3DSA:2.30.30.100 237 281 1.6E-9 T 09-03-2017 UA74_RS27070 3f010780ba97c2c2744a56799cc78505 287 Gene3D G3DSA:3.30.930.10 27 223 4.0E-50 T 09-03-2017 UA74_RS27070 3f010780ba97c2c2744a56799cc78505 287 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 31 283 1.1E-37 T 09-03-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS21180 11ef8d43d2bbec87b5391032a5530711 314 Gene3D G3DSA:3.40.1190.20 3 308 1.5E-86 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS21180 11ef8d43d2bbec87b5391032a5530711 314 Pfam PF00294 pfkB family carbohydrate kinase 5 298 5.1E-60 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS21180 11ef8d43d2bbec87b5391032a5530711 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS21180 11ef8d43d2bbec87b5391032a5530711 314 SUPERFAMILY SSF53613 3 305 7.02E-76 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS08110 077222451b469aa5dabf257401a56816 350 Gene3D G3DSA:2.40.50.100 293 346 3.0E-9 T 09-03-2017 UA74_RS08110 077222451b469aa5dabf257401a56816 350 Pfam PF00005 ABC transporter 19 166 4.5E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS08110 077222451b469aa5dabf257401a56816 350 Gene3D G3DSA:3.40.50.300 18 238 2.6E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08110 077222451b469aa5dabf257401a56816 350 Pfam PF03459 TOBE domain 293 345 2.1E-6 T 09-03-2017 IPR005116 Transport-associated OB, type 1 UA74_RS08110 077222451b469aa5dabf257401a56816 350 SUPERFAMILY SSF52540 15 239 3.69E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08110 077222451b469aa5dabf257401a56816 350 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS08110 077222451b469aa5dabf257401a56816 350 SUPERFAMILY SSF50331 240 348 1.29E-12 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS08110 077222451b469aa5dabf257401a56816 350 SMART SM00382 25 215 1.4E-21 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.90.740.10 300 521 5.6E-48 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF50677 300 516 1.15E-41 T 09-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF52374 513 780 2.53E-104 T 09-03-2017 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF52374 26 173 2.53E-104 T 09-03-2017 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF52374 225 303 2.53E-104 T 09-03-2017 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 223 963 2.9E-210 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 298 501 1.1E-53 T 09-03-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Pfam PF09334 tRNA synthetases class I (M) 65 167 4.8E-12 T 09-03-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:1.10.730.10 761 899 8.1E-36 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 597 615 1.8E-43 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 682 692 1.8E-43 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 649 671 1.8E-43 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 170 1.8E-43 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 292 311 1.8E-43 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 263 276 1.8E-43 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 69 79 - T 09-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Pfam PF08264 Anticodon-binding domain of tRNA 810 925 3.5E-16 T 09-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF47323 775 963 2.8E-33 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 21 963 21.135 T 09-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.40.50.620 224 299 6.5E-132 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.40.50.620 731 760 6.5E-132 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.40.50.620 25 172 6.5E-132 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS30345 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.40.50.620 522 698 6.5E-132 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS21420 9c6e09be7e660232be04c38d759d7470 262 Gene3D G3DSA:3.40.50.300 5 230 2.4E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21420 9c6e09be7e660232be04c38d759d7470 262 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS21420 9c6e09be7e660232be04c38d759d7470 262 Pfam PF00005 ABC transporter 25 166 8.5E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS21420 9c6e09be7e660232be04c38d759d7470 262 SMART SM00382 28 216 2.6E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS21420 9c6e09be7e660232be04c38d759d7470 262 SUPERFAMILY SSF52540 3 229 5.13E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14915 5e70f66fe3f82040b266d13aaea77bf8 433 Gene3D G3DSA:3.90.1150.10 299 429 3.2E-10 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS14915 5e70f66fe3f82040b266d13aaea77bf8 433 Pfam PF00155 Aminotransferase class I and II 71 420 8.8E-25 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS14915 5e70f66fe3f82040b266d13aaea77bf8 433 SUPERFAMILY SSF53383 31 426 3.98E-68 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS14915 5e70f66fe3f82040b266d13aaea77bf8 433 Gene3D G3DSA:3.40.640.10 76 298 3.8E-58 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Gene3D G3DSA:1.25.40.10 1096 1152 2.6E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Gene3D G3DSA:1.25.40.10 167 227 2.6E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 95 1.4E-5 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Pfam PF13191 AAA ATPase domain 299 500 2.1E-19 T 09-03-2017 UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Gene3D G3DSA:1.10.10.10 16 98 3.9E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Pfam PF03704 Bacterial transcriptional activator domain 102 247 1.3E-40 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 SUPERFAMILY SSF52540 444 577 6.77E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 SUPERFAMILY SSF52540 299 364 6.77E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 SUPERFAMILY SSF46894 4 95 1.56E-9 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 SMART SM01043 102 247 7.2E-49 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Gene3D G3DSA:3.40.50.300 300 361 1.4E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 Gene3D G3DSA:3.40.50.300 416 513 1.4E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 SMART SM00862 16 95 4.8E-5 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS26425 a96a14058bccbca35e8127cc4bed4307 1176 SUPERFAMILY SSF48452 98 269 5.14E-37 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS13985 cc34e9611d5a38f5ecf5f5249743f3c8 396 SMART SM00922 165 261 3.2E-20 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS13985 cc34e9611d5a38f5ecf5f5249743f3c8 396 Gene3D G3DSA:3.30.390.10 17 145 2.8E-34 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS13985 cc34e9611d5a38f5ecf5f5249743f3c8 396 SUPERFAMILY SSF51604 146 389 2.23E-60 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS13985 cc34e9611d5a38f5ecf5f5249743f3c8 396 SUPERFAMILY SSF54826 18 147 9.64E-24 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS13985 cc34e9611d5a38f5ecf5f5249743f3c8 396 Pfam PF13378 Enolase C-terminal domain-like 172 382 4.7E-52 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS13985 cc34e9611d5a38f5ecf5f5249743f3c8 396 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 50 147 5.8E-15 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS13985 cc34e9611d5a38f5ecf5f5249743f3c8 396 Gene3D G3DSA:3.20.20.120 146 376 3.2E-62 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS12685 8766f6af5411c645a44900dde2af6337 520 SUPERFAMILY SSF109604 20 176 1.42E-44 T 09-03-2017 UA74_RS12685 8766f6af5411c645a44900dde2af6337 520 SUPERFAMILY SSF109604 228 274 1.42E-44 T 09-03-2017 UA74_RS12685 8766f6af5411c645a44900dde2af6337 520 Gene3D G3DSA:1.10.3410.10 247 278 5.6E-10 T 09-03-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain UA74_RS12685 8766f6af5411c645a44900dde2af6337 520 SMART SM00471 53 260 3.2E-10 T 09-03-2017 IPR003607 HD/PDEase domain UA74_RS12685 8766f6af5411c645a44900dde2af6337 520 Pfam PF01966 HD domain 57 138 3.7E-11 T 09-03-2017 IPR006674 HD domain UA74_RS12685 8766f6af5411c645a44900dde2af6337 520 Gene3D G3DSA:1.10.3210.10 7 246 8.1E-47 T 09-03-2017 IPR006674 HD domain UA74_RS12685 8766f6af5411c645a44900dde2af6337 520 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 21 506 2.2E-56 T 09-03-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 SMART SM00382 1068 1254 9.2E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 SMART SM00382 376 574 5.4E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 SUPERFAMILY SSF52540 1033 1277 1.81E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Gene3D G3DSA:3.40.50.300 351 579 1.7E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Gene3D G3DSA:3.40.50.300 1042 1273 1.2E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 SUPERFAMILY SSF90123 709 1028 8.37E-75 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 SUPERFAMILY SSF52540 343 588 6.69E-79 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Pfam PF00664 ABC transporter transmembrane region 36 304 1.7E-35 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Pfam PF00664 ABC transporter transmembrane region 725 995 4.0E-38 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Pfam PF00005 ABC transporter 367 520 9.0E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Pfam PF00005 ABC transporter 1059 1208 7.7E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 SUPERFAMILY SSF90123 23 339 4.45E-69 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Gene3D G3DSA:1.20.1560.10 712 1026 2.5E-77 T 09-03-2017 UA74_RS26465 6a9b7dbebd1449a56ed0cbaf307eb45a 1289 Gene3D G3DSA:1.20.1560.10 23 339 6.7E-65 T 09-03-2017 UA74_RS12850 e453602c3ce19c91315caeb33f42213e 269 Gene3D G3DSA:3.40.50.150 13 259 3.7E-43 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12850 e453602c3ce19c91315caeb33f42213e 269 Pfam PF13847 Methyltransferase domain 38 154 3.9E-23 T 09-03-2017 IPR025714 Methyltransferase domain UA74_RS12850 e453602c3ce19c91315caeb33f42213e 269 SUPERFAMILY SSF53335 8 256 1.42E-41 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS03440 c3d3900204f7d6dbc9defc1302136db9 286 Pfam PF01026 TatD related DNase 21 271 1.1E-71 T 09-03-2017 IPR001130 TatD family GO:0016788 UA74_RS03440 c3d3900204f7d6dbc9defc1302136db9 286 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 208 224 - T 09-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 UA74_RS03440 c3d3900204f7d6dbc9defc1302136db9 286 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 21 272 4.1E-79 T 09-03-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 UA74_RS03440 c3d3900204f7d6dbc9defc1302136db9 286 PIRSF PIRSF005902 5 276 1.1E-72 T 09-03-2017 IPR001130 TatD family GO:0016788 UA74_RS03440 c3d3900204f7d6dbc9defc1302136db9 286 SUPERFAMILY SSF51556 19 273 3.41E-78 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS03440 c3d3900204f7d6dbc9defc1302136db9 286 Gene3D G3DSA:3.20.20.140 13 274 9.3E-85 T 09-03-2017 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 274 366 1.1E-20 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 Hamap MF_00259 Aminomethyltransferase [gcvT]. 11 372 39.493 T 09-03-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 Gene3D G3DSA:3.30.70.1400 65 147 6.4E-25 T 09-03-2017 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 13 371 5.4E-89 T 09-03-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 Pfam PF01571 Aminomethyltransferase folate-binding domain 17 267 7.4E-81 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 Gene3D G3DSA:2.40.30.110 290 373 3.2E-23 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 SUPERFAMILY SSF101790 281 372 7.36E-22 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 PIRSF PIRSF006487 1 375 8.1E-82 T 09-03-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 Gene3D G3DSA:3.30.1360.120 152 244 2.2E-45 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 Gene3D G3DSA:3.30.1360.120 13 64 2.2E-45 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS25190 ce8e9316e7fef0bc90f2400013a90119 375 SUPERFAMILY SSF103025 12 288 5.02E-87 T 09-03-2017 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 106 117 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 292 303 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 310 337 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 364 373 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 373 384 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 338 353 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 158 174 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 210 232 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 175 190 1.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 Gene3D G3DSA:1.10.630.10 11 424 4.2E-114 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 Pfam PF00067 Cytochrome P450 198 394 4.5E-21 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14400 42de8b378396628a2189c582d319ffb2 424 SUPERFAMILY SSF48264 16 423 8.12E-92 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04650 22a45e3028eb7fd0e3cd4094a2afc019 318 PIRSF PIRSF015582 2 313 7.8E-86 T 09-03-2017 IPR011206 Citrate lyase beta subunit-like UA74_RS04650 22a45e3028eb7fd0e3cd4094a2afc019 318 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 240 6.2E-42 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 UA74_RS04650 22a45e3028eb7fd0e3cd4094a2afc019 318 SUPERFAMILY SSF51621 5 251 3.01E-65 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS04650 22a45e3028eb7fd0e3cd4094a2afc019 318 Gene3D G3DSA:3.20.20.60 4 251 1.6E-76 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS30090 7f0dc3e4c550ed446226acb5a446c2b9 321 Gene3D G3DSA:3.40.50.920 193 316 3.1E-39 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS30090 7f0dc3e4c550ed446226acb5a446c2b9 321 Pfam PF02779 Transketolase, pyrimidine binding domain 1 175 9.7E-43 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS30090 7f0dc3e4c550ed446226acb5a446c2b9 321 Pfam PF02780 Transketolase, C-terminal domain 193 311 2.2E-32 T 09-03-2017 IPR033248 Transketolase, C-terminal domain UA74_RS30090 7f0dc3e4c550ed446226acb5a446c2b9 321 SMART SM00861 1 176 4.5E-68 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS30090 7f0dc3e4c550ed446226acb5a446c2b9 321 Gene3D G3DSA:3.40.50.970 1 179 3.8E-71 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS30090 7f0dc3e4c550ed446226acb5a446c2b9 321 SUPERFAMILY SSF52518 2 179 4.98E-64 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS30090 7f0dc3e4c550ed446226acb5a446c2b9 321 SUPERFAMILY SSF52922 188 320 7.2E-34 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS19620 29dc9871605cd3b851a8891a2a02fcfc 322 Gene3D G3DSA:3.90.180.10 3 91 1.2E-9 T 09-03-2017 IPR011032 GroES-like UA74_RS19620 29dc9871605cd3b851a8891a2a02fcfc 322 SUPERFAMILY SSF51735 125 280 5.68E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19620 29dc9871605cd3b851a8891a2a02fcfc 322 Pfam PF16912 Glucose dehydrogenase C-terminus 136 305 5.8E-13 T 09-03-2017 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 UA74_RS19620 29dc9871605cd3b851a8891a2a02fcfc 322 Gene3D G3DSA:3.90.180.10 95 147 2.2E-4 T 09-03-2017 IPR011032 GroES-like UA74_RS19620 29dc9871605cd3b851a8891a2a02fcfc 322 Gene3D G3DSA:3.40.50.720 148 262 5.2E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19620 29dc9871605cd3b851a8891a2a02fcfc 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 98 4.7E-6 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS19620 29dc9871605cd3b851a8891a2a02fcfc 322 SUPERFAMILY SSF50129 1 153 7.15E-15 T 09-03-2017 IPR011032 GroES-like UA74_RS24085 67e02805dc74f3962996fba1a1f5f64d 246 SMART SM00382 31 210 4.2E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS24085 67e02805dc74f3962996fba1a1f5f64d 246 Pfam PF00005 ABC transporter 22 159 1.3E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS24085 67e02805dc74f3962996fba1a1f5f64d 246 Gene3D G3DSA:3.40.50.300 2 212 8.1E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24085 67e02805dc74f3962996fba1a1f5f64d 246 SUPERFAMILY SSF52540 2 233 1.15E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24085 67e02805dc74f3962996fba1a1f5f64d 246 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 221 4.0E-21 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 PRINTS PR00723 Subtilisin serine protease family (S8) signature 240 253 4.0E-21 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 4.0E-21 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 Gene3D G3DSA:2.60.40.360 471 565 7.6E-4 T 09-03-2017 IPR008962 PapD-like UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 Gene3D G3DSA:3.40.50.200 168 469 2.5E-86 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 Pfam PF00082 Subtilase family 202 458 2.3E-57 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 SUPERFAMILY SSF52743 186 470 2.49E-81 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS20595 40a7fe97a72fbe795b0bb13b4945e6a3 1086 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 244 254 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SUPERFAMILY SSF46894 50 129 2.27E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Pfam PF00486 Transcriptional regulatory protein, C terminal 61 129 1.1E-11 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SUPERFAMILY SSF48452 134 292 7.11E-24 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Gene3D G3DSA:1.25.40.10 829 1017 4.1E-31 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SUPERFAMILY SSF81901 681 851 2.35E-8 T 09-03-2017 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Pfam PF00931 NB-ARC domain 312 503 2.6E-9 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 PRINTS PR00364 Disease resistance protein signature 493 507 3.6E-6 T 09-03-2017 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 PRINTS PR00364 Disease resistance protein signature 327 342 3.6E-6 T 09-03-2017 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 PRINTS PR00364 Disease resistance protein signature 405 419 3.6E-6 T 09-03-2017 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Gene3D G3DSA:3.40.50.300 305 430 4.6E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00862 54 129 6.2E-17 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Pfam PF13424 Tetratricopeptide repeat 941 1013 4.6E-12 T 09-03-2017 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Pfam PF13424 Tetratricopeptide repeat 823 894 9.0E-11 T 09-03-2017 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Pfam PF13424 Tetratricopeptide repeat 742 814 3.5E-9 T 09-03-2017 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Gene3D G3DSA:1.10.10.10 50 132 3.1E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM01043 136 277 2.3E-39 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SUPERFAMILY SSF48452 823 1014 2.2E-30 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Pfam PF13374 Tetratricopeptide repeat 906 932 2.3E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Pfam PF03704 Bacterial transcriptional activator domain 136 277 2.0E-31 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 Gene3D G3DSA:1.25.40.10 696 818 7.3E-14 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00028 823 856 9.8E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00028 783 816 4.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00028 982 1015 2.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00028 863 896 39.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00028 743 776 50.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00028 942 975 0.57 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SMART SM00028 903 936 0.012 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS13290 aa15290680556f0244ee89bed10e8aa1 1037 SUPERFAMILY SSF52540 300 560 3.95E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 Gene3D G3DSA:1.20.120.140 206 285 8.5E-18 T 09-03-2017 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 SMART SM00962 300 499 1.6E-100 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 Gene3D G3DSA:3.40.50.300 294 498 7.1E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 SMART SM00963 203 283 5.1E-15 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 SUPERFAMILY SSF52540 295 498 4.31E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 227 498 1.4E-102 T 09-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 Pfam PF00448 SRP54-type protein, GTPase domain 300 498 2.7E-72 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 Pfam PF02881 SRP54-type protein, helical bundle domain 218 277 2.9E-7 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 SUPERFAMILY SSF47364 198 277 8.9E-16 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 226 499 57.559 T 09-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 SMART SM00382 299 449 4.5E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS25670 485f969221e2e7c747bb6976b132768e 499 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 472 485 - T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS13535 4f00692a3cabe1522988c1773443f483 296 Pfam PF03747 ADP-ribosylglycohydrolase 12 270 4.1E-47 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 UA74_RS13535 4f00692a3cabe1522988c1773443f483 296 SUPERFAMILY SSF101478 3 271 8.24E-53 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 UA74_RS20830 bf22f92c744f4ca14a804a1064ee56ac 590 Gene3D G3DSA:3.55.50.10 112 187 1.0E-4 T 09-03-2017 UA74_RS20830 bf22f92c744f4ca14a804a1064ee56ac 590 SUPERFAMILY SSF69349 450 579 8.63E-5 T 09-03-2017 UA74_RS20830 bf22f92c744f4ca14a804a1064ee56ac 590 Gene3D G3DSA:2.40.50.230 390 458 7.3E-11 T 09-03-2017 IPR006531 Gp5 N-terminal UA74_RS20830 bf22f92c744f4ca14a804a1064ee56ac 590 SUPERFAMILY SSF69279 29 183 2.38E-19 T 09-03-2017 UA74_RS20830 bf22f92c744f4ca14a804a1064ee56ac 590 SUPERFAMILY SSF69255 382 458 4.71E-12 T 09-03-2017 UA74_RS20830 bf22f92c744f4ca14a804a1064ee56ac 590 Pfam PF05954 Phage late control gene D protein (GPD) 40 348 2.0E-16 T 09-03-2017 UA74_RS09675 181eb6c33380286c5c5c76f9b73be37c 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 136 4.4E-36 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UA74_RS09675 181eb6c33380286c5c5c76f9b73be37c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 4.7E-19 T 09-03-2017 IPR020603 MraZ domain UA74_RS09675 181eb6c33380286c5c5c76f9b73be37c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 136 4.8E-19 T 09-03-2017 IPR020603 MraZ domain UA74_RS09675 181eb6c33380286c5c5c76f9b73be37c 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 51.492 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UA74_RS09675 181eb6c33380286c5c5c76f9b73be37c 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 123 1.0E-46 T 09-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UA74_RS09675 181eb6c33380286c5c5c76f9b73be37c 143 SUPERFAMILY SSF89447 1 135 1.26E-45 T 09-03-2017 UA74_RS23870 08ed325818664b43866037d0bcf95ef5 383 SUPERFAMILY SSF51735 49 173 1.4E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23870 08ed325818664b43866037d0bcf95ef5 383 Gene3D G3DSA:3.40.50.720 49 158 2.2E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23870 08ed325818664b43866037d0bcf95ef5 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 138 5.4E-8 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS23870 08ed325818664b43866037d0bcf95ef5 383 SUPERFAMILY SSF55347 146 342 6.54E-29 T 09-03-2017 UA74_RS23870 08ed325818664b43866037d0bcf95ef5 383 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 228 3.1E-5 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS23870 08ed325818664b43866037d0bcf95ef5 383 Gene3D G3DSA:3.30.360.10 159 371 7.2E-38 T 09-03-2017 UA74_RS12975 874a46c37dcff9f22c096c594377bbdf 499 PIRSF PIRSF018077 8 496 3.5E-202 T 09-03-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UA74_RS12975 874a46c37dcff9f22c096c594377bbdf 499 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 485 1.3E-230 T 09-03-2017 IPR022366 Pup deamidase GO:0008233|GO:0016811 UA74_RS12975 874a46c37dcff9f22c096c594377bbdf 499 Pfam PF03136 Pup-ligase protein 3 454 3.5E-180 T 09-03-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 SUPERFAMILY SSF56801 50 643 2.62E-124 T 09-03-2017 UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 ProSitePatterns PS00455 Putative AMP-binding domain signature. 284 295 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 Pfam PF00501 AMP-binding enzyme 111 541 7.3E-51 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 Gene3D G3DSA:3.40.50.980 112 289 3.3E-28 T 09-03-2017 UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 49 104 7.7E-14 T 09-03-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 666 3.1E-243 T 09-03-2017 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 Gene3D G3DSA:3.40.50.980 290 441 7.8E-21 T 09-03-2017 UA74_RS00790 d12f68b6be5ac17c9853f11ef32fb3e4 693 Gene3D G3DSA:3.30.300.30 540 641 4.5E-9 T 09-03-2017 UA74_RS29075 764b6490509215f63647dba14cb99882 275 SUPERFAMILY SSF140959 20 272 1.96E-73 T 09-03-2017 UA74_RS29075 764b6490509215f63647dba14cb99882 275 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 14 275 34.902 T 09-03-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 UA74_RS29075 764b6490509215f63647dba14cb99882 275 Pfam PF03301 Tryptophan 2,3-dioxygenase 16 273 9.7E-56 T 09-03-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 Gene3D G3DSA:3.30.70.270 408 560 4.2E-46 T 09-03-2017 UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 403 560 3.5E-39 T 09-03-2017 IPR000160 GGDEF domain UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 Gene3D G3DSA:1.25.40.10 33 110 7.4E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 Gene3D G3DSA:1.25.40.10 161 239 7.4E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 Gene3D G3DSA:1.25.40.10 295 336 7.4E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 Pfam PF00990 Diguanylate cyclase, GGDEF domain 406 556 3.9E-38 T 09-03-2017 IPR000160 GGDEF domain UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 SMART SM00267 395 561 8.5E-47 T 09-03-2017 IPR000160 GGDEF domain UA74_RS03650 48e319ded2060c9a0c4077917721f528 579 SUPERFAMILY SSF55073 411 559 1.94E-40 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS23070 62105ca623437c095a48fa6249c59083 254 SMART SM00849 21 198 0.0048 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS23070 62105ca623437c095a48fa6249c59083 254 Gene3D G3DSA:3.60.15.10 2 251 1.8E-55 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS23070 62105ca623437c095a48fa6249c59083 254 Pfam PF12706 Beta-lactamase superfamily domain 32 220 5.6E-23 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS23070 62105ca623437c095a48fa6249c59083 254 SUPERFAMILY SSF56281 6 251 1.1E-49 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS30000 1796fb736d482f9d448a1269db782025 290 Gene3D G3DSA:2.40.30.10 3 130 2.6E-30 T 09-03-2017 UA74_RS30000 1796fb736d482f9d448a1269db782025 290 Pfam PF08021 Siderophore-interacting FAD-binding domain 10 130 1.7E-28 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting UA74_RS30000 1796fb736d482f9d448a1269db782025 290 Pfam PF04954 Siderophore-interacting protein 149 265 5.9E-35 T 09-03-2017 IPR007037 Siderophore-interacting protein UA74_RS30000 1796fb736d482f9d448a1269db782025 290 Gene3D G3DSA:3.40.50.80 149 270 1.9E-40 T 09-03-2017 UA74_RS30000 1796fb736d482f9d448a1269db782025 290 SUPERFAMILY SSF63380 77 132 5.78E-9 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS30000 1796fb736d482f9d448a1269db782025 290 SUPERFAMILY SSF63380 8 47 5.78E-9 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS11365 d6b8efa24aec35897da92a04fafecd9f 340 Gene3D G3DSA:1.10.3470.10 45 257 5.7E-6 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS11365 d6b8efa24aec35897da92a04fafecd9f 340 Pfam PF00950 ABC 3 transport family 16 273 1.3E-54 T 09-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_RS11365 d6b8efa24aec35897da92a04fafecd9f 340 SUPERFAMILY SSF81345 19 265 4.05E-22 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS01895 35d61261fa982b54cb0ec578b823813b 258 SUPERFAMILY SSF110399 3 241 2.75E-78 T 09-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 UA74_RS01895 35d61261fa982b54cb0ec578b823813b 258 Hamap MF_00443 Thiazole synthase [thiG]. 4 256 41.016 T 09-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 UA74_RS01895 35d61261fa982b54cb0ec578b823813b 258 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 249 2.0E-102 T 09-03-2017 UA74_RS01895 35d61261fa982b54cb0ec578b823813b 258 Gene3D G3DSA:3.20.20.70 4 249 2.4E-54 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 Gene3D G3DSA:3.30.9.10 223 323 1.3E-13 T 09-03-2017 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 Gene3D G3DSA:3.30.9.10 91 143 1.3E-13 T 09-03-2017 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 Pfam PF01266 FAD dependent oxidoreductase 4 362 2.4E-59 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 SUPERFAMILY SSF51905 2 223 4.99E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 SUPERFAMILY SSF51905 325 381 4.99E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 Gene3D G3DSA:3.50.50.60 325 380 1.6E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 Gene3D G3DSA:3.50.50.60 1 79 1.6E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 Gene3D G3DSA:3.50.50.60 144 222 1.6E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17050 3757d4cf7ed9afc3eab9782e1480aec4 394 SUPERFAMILY SSF54373 223 323 1.12E-11 T 09-03-2017 UA74_RS14835 046bf42cbe9f64a6b8fb6066b7b84908 265 Gene3D G3DSA:3.20.20.190 15 263 1.9E-63 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS14835 046bf42cbe9f64a6b8fb6066b7b84908 265 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 22 125 1.6E-18 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_RS14835 046bf42cbe9f64a6b8fb6066b7b84908 265 Pfam PF13653 Glycerophosphoryl diester phosphodiesterase family 221 249 1.5E-8 T 09-03-2017 UA74_RS14835 046bf42cbe9f64a6b8fb6066b7b84908 265 SUPERFAMILY SSF51695 15 253 3.4E-52 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS04645 0898b05cbcc2c65bad57cc5edb6af608 172 Gene3D G3DSA:1.10.10.10 10 149 5.0E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04645 0898b05cbcc2c65bad57cc5edb6af608 172 Pfam PF12802 MarR family 42 101 4.5E-12 T 09-03-2017 UA74_RS04645 0898b05cbcc2c65bad57cc5edb6af608 172 SMART SM00347 35 137 2.7E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS04645 0898b05cbcc2c65bad57cc5edb6af608 172 SUPERFAMILY SSF46785 11 148 6.23E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04645 0898b05cbcc2c65bad57cc5edb6af608 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 6.2E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS04645 0898b05cbcc2c65bad57cc5edb6af608 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 6.2E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS04645 0898b05cbcc2c65bad57cc5edb6af608 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 6.2E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS24835 9ed86bca39608b038a6e40f31e99ba0c 369 SUPERFAMILY SSF53137 132 221 1.22E-5 T 09-03-2017 UA74_RS24835 9ed86bca39608b038a6e40f31e99ba0c 369 Gene3D G3DSA:3.30.1330.30 256 300 3.1E-5 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS24835 9ed86bca39608b038a6e40f31e99ba0c 369 SUPERFAMILY SSF55315 256 367 1.53E-7 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS24835 9ed86bca39608b038a6e40f31e99ba0c 369 Pfam PF03465 eRF1 domain 3 256 302 8.3E-5 T 09-03-2017 IPR005142 eRF1 domain 3 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 10 347 32.815 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 Pfam PF02885 Glycosyl transferase family, helical bundle domain 10 69 1.4E-14 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 Gene3D G3DSA:1.20.970.10 7 70 1.4E-18 T 09-03-2017 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 Gene3D G3DSA:3.40.1030.10 79 347 2.2E-96 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 SUPERFAMILY SSF52418 81 348 3.79E-76 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 SUPERFAMILY SSF47648 7 74 3.79E-15 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 Pfam PF00591 Glycosyl transferase family, a/b domain 80 337 4.6E-79 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS15895 6b9e0bf8c3957a839a153e8a07c03a82 355 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 13 346 3.7E-103 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 29 261 8.7E-57 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 23 275 16.504 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 ProSitePatterns PS01218 TatC family signature. 188 207 - T 09-03-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 Pfam PF00902 Sec-independent protein translocase protein (TatC) 31 254 1.7E-52 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 28 55 3.0E-37 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 138 164 3.0E-37 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 120 138 3.0E-37 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_RS07000 bd516d8ce23003bdb49f9a49e6003e75 313 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 188 216 3.0E-37 T 09-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_RS18165 39fe6c666064ae661558e1cdf82b1dff 251 Pfam PF12730 ABC-2 family transporter protein 6 184 1.8E-9 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 UA74_RS15540 26116a265284885065f784743273e55c 272 SUPERFAMILY SSF53474 4 264 7.71E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15540 26116a265284885065f784743273e55c 272 Pfam PF12697 Alpha/beta hydrolase family 28 258 5.5E-22 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15540 26116a265284885065f784743273e55c 272 Gene3D G3DSA:3.40.50.1820 2 265 1.6E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15540 26116a265284885065f784743273e55c 272 PRINTS PR00412 Epoxide hydrolase signature 94 107 5.2E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15540 26116a265284885065f784743273e55c 272 PRINTS PR00412 Epoxide hydrolase signature 240 262 5.2E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15540 26116a265284885065f784743273e55c 272 PRINTS PR00412 Epoxide hydrolase signature 51 66 5.2E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15540 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 1.9E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15540 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.9E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15540 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.9E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15540 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.9E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 113 126 - T 09-03-2017 IPR033135 ClpP, histidine active site UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 SUPERFAMILY SSF52096 21 193 5.39E-63 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 20 35 5.8E-43 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 91 108 5.8E-43 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 60 80 5.8E-43 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 112 131 5.8E-43 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 169 188 5.8E-43 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 194 38.975 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 Gene3D G3DSA:3.90.226.10 20 195 3.4E-73 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS18900 5063aa57e2964a1c1a2de55b53810795 201 Pfam PF00574 Clp protease 19 192 2.5E-74 T 09-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UA74_RS05845 f1e7b9cbcef49e5b840241a4127ae25b 286 Gene3D G3DSA:3.10.450.50 5 126 2.0E-13 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS05845 f1e7b9cbcef49e5b840241a4127ae25b 286 Pfam PF07366 SnoaL-like polyketide cyclase 5 105 8.7E-13 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS05845 f1e7b9cbcef49e5b840241a4127ae25b 286 SUPERFAMILY SSF54427 3 126 3.09E-15 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS29895 b2d3e933aff84a69ff9cb962d70690c7 278 SUPERFAMILY SSF52540 16 249 2.92E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29895 b2d3e933aff84a69ff9cb962d70690c7 278 SMART SM00382 50 235 2.1E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS29895 b2d3e933aff84a69ff9cb962d70690c7 278 Pfam PF00005 ABC transporter 41 188 4.1E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS29895 b2d3e933aff84a69ff9cb962d70690c7 278 Gene3D G3DSA:3.40.50.300 21 253 8.9E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29895 b2d3e933aff84a69ff9cb962d70690c7 278 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.30.420.40 292 333 1.4E-31 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.30.420.40 167 201 1.4E-31 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF100934 508 565 1.73E-5 T 09-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF53067 162 356 2.22E-61 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 618 35.838 T 09-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF53067 4 160 3.08E-58 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.90.640.10 202 288 3.7E-28 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:2.60.34.10 364 506 2.3E-71 T 09-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 443 459 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 362 381 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 174 184 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 339 359 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 114 134 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 307 323 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.2E-74 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 577 7.1E-273 T 09-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:1.20.1270.10 507 577 7.1E-26 T 09-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.30.30.30 39 100 2.0E-16 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Pfam PF00012 Hsp70 protein 4 577 1.7E-237 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF100920 358 514 1.11E-57 T 09-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.30.420.40 4 38 2.1E-57 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.30.420.40 101 166 2.1E-57 T 09-03-2017 UA74_RS29880 dda1ed766d29fac4b68b39e26bfc2230 624 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS29660 27b35552d250601c587620ce5526f266 199 SUPERFAMILY SSF88659 123 197 6.54E-18 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29660 27b35552d250601c587620ce5526f266 199 Pfam PF08281 Sigma-70, region 4 139 191 1.7E-19 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29660 27b35552d250601c587620ce5526f266 199 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 42 193 6.4E-50 T 09-03-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_RS29660 27b35552d250601c587620ce5526f266 199 Gene3D G3DSA:1.10.1740.10 42 124 5.1E-14 T 09-03-2017 UA74_RS29660 27b35552d250601c587620ce5526f266 199 SUPERFAMILY SSF88946 42 118 1.37E-14 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29660 27b35552d250601c587620ce5526f266 199 Gene3D G3DSA:1.10.10.10 137 195 1.2E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29660 27b35552d250601c587620ce5526f266 199 Pfam PF04542 Sigma-70 region 2 46 112 1.8E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29660 27b35552d250601c587620ce5526f266 199 SMART SM00421 145 197 0.0098 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29660 27b35552d250601c587620ce5526f266 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 193 2.6E-24 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS29775 11d3dc1287ef3ce27835d967f67b740e 504 Pfam PF00939 Sodium:sulfate symporter transmembrane region 23 493 1.5E-90 T 09-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UA74_RS29775 11d3dc1287ef3ce27835d967f67b740e 504 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 50 492 3.4E-97 T 09-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UA74_RS06890 ca055e9b4fe23c304cb8eaef497379ad 65 Gene3D G3DSA:1.10.260.40 3 64 1.8E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06890 ca055e9b4fe23c304cb8eaef497379ad 65 Pfam PF13560 Helix-turn-helix domain 7 65 3.1E-12 T 09-03-2017 UA74_RS06890 ca055e9b4fe23c304cb8eaef497379ad 65 SMART SM00530 10 65 2.2E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS06890 ca055e9b4fe23c304cb8eaef497379ad 65 SUPERFAMILY SSF47413 5 64 1.8E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09020 786e9a10d68a8730b01b986fcce714b7 323 Gene3D G3DSA:1.10.443.10 153 315 2.0E-49 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS09020 786e9a10d68a8730b01b986fcce714b7 323 Gene3D G3DSA:1.10.150.130 25 118 6.6E-20 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS09020 786e9a10d68a8730b01b986fcce714b7 323 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 27 323 52.021 T 09-03-2017 IPR023009 Tyrosine recombinase XerC/XerD UA74_RS09020 786e9a10d68a8730b01b986fcce714b7 323 Pfam PF00589 Phage integrase family 154 308 3.1E-40 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS09020 786e9a10d68a8730b01b986fcce714b7 323 SUPERFAMILY SSF47823 31 120 2.55E-11 T 09-03-2017 IPR010998 Integrase, Lambda-type, N-terminal UA74_RS09020 786e9a10d68a8730b01b986fcce714b7 323 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 31 110 1.3E-15 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_RS09020 786e9a10d68a8730b01b986fcce714b7 323 SUPERFAMILY SSF56349 129 321 3.53E-46 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS23880 c06441938d683328c804ae8f03516326 313 SUPERFAMILY SSF161098 68 295 1.19E-52 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23880 c06441938d683328c804ae8f03516326 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 295 5.1E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23880 c06441938d683328c804ae8f03516326 313 SUPERFAMILY SSF160964 26 71 1.96E-5 T 09-03-2017 UA74_RS23880 c06441938d683328c804ae8f03516326 313 Gene3D G3DSA:1.10.3720.10 20 297 3.5E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 SUPERFAMILY SSF48264 5 389 2.62E-78 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 Gene3D G3DSA:1.10.630.10 5 389 9.7E-102 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 262 273 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 122 138 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 139 154 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 181 203 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 338 349 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 75 86 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 281 308 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 309 324 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 329 338 3.2E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 331 340 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 262 273 3.5E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 338 349 3.5E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 228 245 3.5E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 329 338 3.5E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06750 22d660f489d3d57ca4baf7902b28beb3 389 Pfam PF00067 Cytochrome P450 261 358 1.3E-16 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 SUPERFAMILY SSF55021 340 413 6.87E-11 T 09-03-2017 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 Pfam PF01842 ACT domain 345 406 1.1E-8 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 SUPERFAMILY SSF55347 127 297 1.31E-50 T 09-03-2017 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 SUPERFAMILY SSF51735 1 148 1.01E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 PIRSF PIRSF000098 1 421 1.4E-151 T 09-03-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 Gene3D G3DSA:3.30.70.260 342 412 2.4E-8 T 09-03-2017 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 Pfam PF00742 Homoserine dehydrogenase 127 310 2.7E-65 T 09-03-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 Gene3D G3DSA:3.30.360.10 139 294 2.5E-53 T 09-03-2017 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 Gene3D G3DSA:3.40.50.720 1 138 2.0E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 173 195 - T 09-03-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UA74_RS07075 1e03a5d2681bd7f2626f0e2a193a8cfb 423 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 3 119 8.2E-25 T 09-03-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 5.8E-14 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 5.8E-14 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 5.8E-14 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 437 5.8E-14 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 334 6.3E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 SUPERFAMILY SSF158472 207 256 2.22E-9 T 09-03-2017 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 481 5.7E-19 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 SUPERFAMILY SSF47384 251 334 5.3E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 SMART SM00388 267 334 1.1E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 Pfam PF00672 HAMP domain 192 255 2.1E-15 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 SUPERFAMILY SSF55874 323 481 5.37E-37 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 Gene3D G3DSA:3.30.565.10 322 481 7.6E-41 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 SMART SM00387 374 483 2.0E-31 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 Gene3D G3DSA:1.10.287.130 259 321 3.5E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS20745 26afb1337fa5fe928805bc6cf96b0db4 486 SMART SM00304 207 259 1.2E-15 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS24515 5e1a5bec07c8d5515e6aeb657b6d717f 137 SUPERFAMILY SSF46785 13 135 2.44E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24515 5e1a5bec07c8d5515e6aeb657b6d717f 137 Pfam PF01475 Ferric uptake regulator family 13 129 6.8E-37 T 09-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 UA74_RS24515 5e1a5bec07c8d5515e6aeb657b6d717f 137 Gene3D G3DSA:1.10.10.10 13 82 1.2E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 Gene3D G3DSA:3.30.428.10 204 364 2.1E-46 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 SUPERFAMILY SSF54197 207 364 9.36E-33 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 Gene3D G3DSA:3.30.428.10 65 202 1.1E-39 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 215 324 1.0E-15 T 09-03-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 SUPERFAMILY SSF54197 39 203 7.37E-51 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 178 195 - T 09-03-2017 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 40 202 3.2E-40 T 09-03-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 42 364 1.5E-45 T 09-03-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_RS03220 5371a53ebbfdda06062dd50092bfce91 365 PIRSF PIRSF000808 34 365 3.3E-105 T 09-03-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_RS14360 26e237a22746c0983126cde66110a3e9 290 Gene3D G3DSA:3.40.50.720 3 154 1.5E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14360 26e237a22746c0983126cde66110a3e9 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 152 5.3E-21 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS14360 26e237a22746c0983126cde66110a3e9 290 PIRSF PIRSF000103 1 290 5.0E-34 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_RS14360 26e237a22746c0983126cde66110a3e9 290 Gene3D G3DSA:1.10.1040.10 186 287 2.3E-5 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS14360 26e237a22746c0983126cde66110a3e9 290 SUPERFAMILY SSF51735 6 153 5.77E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF53474 3763 3801 1.52E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF53474 3854 4093 1.52E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00698 Acyl transferase domain 565 884 5.0E-47 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00698 Acyl transferase domain 2615 2923 7.3E-82 T 09-03-2017 IPR014043 Acyl transferase UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF53901 31 408 3.79E-101 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00825 Beta-ketoacyl synthase 36 462 2.3E-219 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00825 Beta-ketoacyl synthase 2090 2516 5.1E-216 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00824 Thioesterase 3879 4092 3.7E-96 T 09-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF55048 700 761 2.09E-11 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1427 1483 2.5E-6 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00550 Phosphopantetheine attachment site 3736 3801 1.1E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00550 Phosphopantetheine attachment site 1998 2063 2.4E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 3449 3702 4.66E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.366.10 2609 2732 5.2E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.366.10 557 695 1.6E-74 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.366.10 2810 2921 5.2E-68 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.366.10 761 867 1.6E-74 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3760 3775 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF52151 762 861 4.71E-69 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF52151 561 701 4.71E-69 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2088 2338 2.1E-85 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.0E-89 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2616 2920 1.4E-112 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 866 3.6E-114 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00107 Zinc-binding dehydrogenase 1546 1640 5.1E-17 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1535 1556 - T 09-03-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08659 KR domain 3454 3632 2.4E-55 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08659 KR domain 1715 1892 8.6E-57 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF52151 2612 2738 4.19E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF52151 2811 2903 4.19E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.90.180.10 1406 1539 1.1E-44 T 09-03-2017 IPR011032 GroES-like UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.47.10 2351 2516 3.0E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.47.10 297 462 4.9E-64 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2251 2267 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2023 2038 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2466 2584 2.5E-16 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 528 4.1E-15 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00823 Phosphopantetheine attachment site 1996 2068 7.1E-30 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00823 Phosphopantetheine attachment site 3733 3805 6.3E-22 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF50129 1406 1540 7.55E-32 T 09-03-2017 IPR011032 GroES-like UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF47336 3728 3823 1.1E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08990 Erythronolide synthase docking 2 26 2.0E-12 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 1710 1929 7.9E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.47.10 36 296 4.1E-88 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.47.10 2090 2350 6.0E-89 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.720 3453 3648 3.5E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.720 1713 1898 2.6E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1715 1894 4.6E-51 T 09-03-2017 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3454 3634 2.0E-53 T 09-03-2017 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.1820 3822 4094 1.0E-75 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.30.70.250 2737 2809 2.3E-7 T 09-03-2017 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.30.70.250 700 760 4.8E-7 T 09-03-2017 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF53901 2086 2460 5.01E-100 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 1506 1644 9.69E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 1207 1382 1.69E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:1.10.1200.10 1994 2065 1.1E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:1.10.1200.10 3732 3806 1.1E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.720 1540 1636 1.3E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF55048 2737 2810 1.1E-11 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF14765 Polyketide synthase dehydratase 2986 3245 4.1E-34 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF14765 Polyketide synthase dehydratase 931 1202 1.2E-52 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM01294 1997 2064 8.0E-5 T 09-03-2017 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00826 931 1092 4.3E-73 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00826 2986 3165 5.6E-49 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2346 2463 2.4E-43 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.1E-43 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00975 Thioesterase domain 3877 4091 1.4E-21 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00829 1407 1705 4.3E-173 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 3253 3440 1.1E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16485 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF47336 1993 2103 2.49E-23 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF51230 603 673 7.98E-20 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Gene3D G3DSA:3.30.470.20 203 446 6.2E-87 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 3.3E-34 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Gene3D G3DSA:2.40.50.100 607 673 3.2E-21 T 09-03-2017 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF00364 Biotin-requiring enzyme 607 672 2.8E-15 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF56059 83 344 5.13E-63 T 09-03-2017 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Gene3D G3DSA:3.30.1490.20 130 202 8.7E-23 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SMART SM00878 337 443 6.3E-52 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 9.1E-71 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 6.3E-40 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 630 647 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF52440 2 113 1.37E-42 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF51246 332 447 4.34E-36 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS26365 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Gene3D G3DSA:3.40.50.20 2 129 1.7E-45 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS00350 46472d9c69f3994b837517b63c00b326 372 Pfam PF01757 Acyltransferase family 17 336 3.4E-20 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 Gene3D G3DSA:3.40.50.300 404 474 3.1E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 Gene3D G3DSA:3.40.50.300 265 366 3.1E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 287 684 8.9E-46 T 09-03-2017 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 Pfam PF00270 DEAD/DEAH box helicase 278 474 2.7E-5 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 SUPERFAMILY SSF52540 284 336 2.23E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 SUPERFAMILY SSF52540 381 475 2.23E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 SUPERFAMILY SSF52540 533 677 2.23E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 2 209 4.9E-17 T 09-03-2017 IPR006483 CRISPR-associated Cas3-HD domain UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 SMART SM00487 264 511 0.0067 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS23185 b7305624d3675c9b38794f10d8268f18 811 Gene3D G3DSA:3.40.50.300 557 678 3.6E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 SUPERFAMILY SSF47384 163 244 3.14E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 SUPERFAMILY SSF55874 235 401 7.6E-27 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 SMART SM00388 179 244 5.7E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 Gene3D G3DSA:1.10.287.130 169 239 9.9E-11 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 SMART SM00387 286 403 9.3E-25 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 Pfam PF00672 HAMP domain 106 174 4.8E-15 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 244 4.7E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 401 4.4E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 Gene3D G3DSA:3.30.565.10 245 402 2.5E-29 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 SMART SM00304 125 178 7.0E-11 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 340 7.4E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 354 7.4E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 381 7.4E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS02650 13bf3a9db6346a478a19ef95f5caa4cf 409 SUPERFAMILY SSF158472 126 175 5.75E-8 T 09-03-2017 UA74_RS07350 44756b79ab761ab2e18c14bcd07b17eb 321 Pfam PF00085 Thioredoxin 53 156 1.1E-24 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 UA74_RS07350 44756b79ab761ab2e18c14bcd07b17eb 321 Gene3D G3DSA:1.25.40.10 244 321 1.7E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS07350 44756b79ab761ab2e18c14bcd07b17eb 321 Gene3D G3DSA:1.25.40.10 193 228 3.6E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS07350 44756b79ab761ab2e18c14bcd07b17eb 321 Gene3D G3DSA:3.40.30.10 52 159 3.0E-32 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS07350 44756b79ab761ab2e18c14bcd07b17eb 321 Pfam PF14561 Tetratricopeptide repeat 243 321 4.2E-18 T 09-03-2017 UA74_RS07350 44756b79ab761ab2e18c14bcd07b17eb 321 ProSitePatterns PS00194 Thioredoxin family active site. 75 93 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_RS07350 44756b79ab761ab2e18c14bcd07b17eb 321 SUPERFAMILY SSF52833 49 160 5.57E-34 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS08420 7db171caece55df0f327a6b03074140a 305 SUPERFAMILY SSF117892 109 239 5.75E-11 T 09-03-2017 IPR001107 Band 7 domain UA74_RS08420 7db171caece55df0f327a6b03074140a 305 SMART SM00244 73 237 1.2E-7 T 09-03-2017 IPR001107 Band 7 domain UA74_RS08420 7db171caece55df0f327a6b03074140a 305 Pfam PF01145 SPFH domain / Band 7 family 77 249 2.3E-22 T 09-03-2017 IPR001107 Band 7 domain UA74_RS01240 8a67ef00caadf0c3b4099e40b885adcc 198 ProSitePatterns PS00194 Thioredoxin family active site. 88 106 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_RS01240 8a67ef00caadf0c3b4099e40b885adcc 198 Pfam PF00578 AhpC/TSA family 71 172 4.4E-9 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS01240 8a67ef00caadf0c3b4099e40b885adcc 198 SUPERFAMILY SSF52833 66 194 7.19E-20 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS01240 8a67ef00caadf0c3b4099e40b885adcc 198 Gene3D G3DSA:3.40.30.10 4 196 5.2E-23 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 Gene3D G3DSA:3.40.50.720 15 105 2.0E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 Pfam PF01225 Mur ligase family, catalytic domain 17 117 2.6E-25 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 17 473 6.2E-145 T 09-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 Gene3D G3DSA:3.40.1190.10 106 333 3.5E-71 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 SUPERFAMILY SSF53623 104 330 2.49E-52 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 SUPERFAMILY SSF51984 15 105 1.19E-22 T 09-03-2017 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 SUPERFAMILY SSF53244 331 475 1.83E-45 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 Gene3D G3DSA:3.90.190.20 334 477 5.8E-53 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 14 479 38.186 T 09-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 Pfam PF08245 Mur ligase middle domain 123 311 4.9E-27 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09730 ba67e3f6cc6daeb7af7e962090761028 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 417 3.3E-25 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS00755 1e330ed2d517f36f395ee3c67b5612a8 147 Gene3D G3DSA:3.90.79.10 3 124 2.9E-30 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS00755 1e330ed2d517f36f395ee3c67b5612a8 147 SUPERFAMILY SSF55811 3 124 4.33E-31 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS00755 1e330ed2d517f36f395ee3c67b5612a8 147 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS00755 1e330ed2d517f36f395ee3c67b5612a8 147 Pfam PF00293 NUDIX domain 8 116 6.7E-20 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS00755 1e330ed2d517f36f395ee3c67b5612a8 147 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.2E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS00755 1e330ed2d517f36f395ee3c67b5612a8 147 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.2E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.334 T 09-03-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 PRINTS PR01249 Ribosomal protein L31 signature 45 60 5.5E-19 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.5E-19 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 PRINTS PR01249 Ribosomal protein L31 signature 60 78 5.5E-19 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 Pfam PF01197 Ribosomal protein L31 2 79 3.6E-31 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 6.8E-22 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 SUPERFAMILY SSF143800 2 79 7.85E-23 T 09-03-2017 UA74_RS21200 d9f46dcb14cfed58ccfb2039c3754368 89 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02820 f1b9e0af48cc128e1004952d9b498c8d 137 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 83 137 1.5E-20 T 09-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 UA74_RS02820 f1b9e0af48cc128e1004952d9b498c8d 137 Hamap MF_00422 Protein translocase subunit SecE [secE]. 79 134 12.757 T 09-03-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS02820 f1b9e0af48cc128e1004952d9b498c8d 137 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 84 112 - T 09-03-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS02820 f1b9e0af48cc128e1004952d9b498c8d 137 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 83 135 5.5E-19 T 09-03-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_RS02820 f1b9e0af48cc128e1004952d9b498c8d 137 Gene3D G3DSA:1.20.5.1030 80 136 1.3E-22 T 09-03-2017 UA74_RS10845 05c6fbf11473b4c3b34bd419e021b97f 381 Pfam PF13439 Glycosyltransferase Family 4 14 173 2.0E-24 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS10845 05c6fbf11473b4c3b34bd419e021b97f 381 Pfam PF13692 Glycosyl transferases group 1 190 330 1.7E-29 T 09-03-2017 UA74_RS10845 05c6fbf11473b4c3b34bd419e021b97f 381 Gene3D G3DSA:3.40.50.2000 184 342 5.2E-22 T 09-03-2017 UA74_RS10845 05c6fbf11473b4c3b34bd419e021b97f 381 SUPERFAMILY SSF53756 3 365 1.53E-72 T 09-03-2017 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF47336 1783 1871 1.23E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Pfam PF08659 KR domain 2197 2417 1.6E-29 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF51735 1999 2161 3.67E-6 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.30.70.250 1381 1439 1.6E-8 T 09-03-2017 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.40.366.10 1248 1374 1.6E-51 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.40.366.10 1446 1547 1.6E-51 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF55048 1381 1446 6.67E-11 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 970 1087 3.3E-38 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1255 1567 6.9E-33 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Pfam PF03060 Nitronate monooxygenase 332 663 2.4E-13 T 09-03-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:1.10.1200.10 1782 1855 1.7E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 875 891 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Pfam PF00698 Acyl transferase domain 1255 1535 3.0E-30 T 09-03-2017 IPR014043 Acyl transferase UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.20.20.70 81 174 1.7E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF53901 858 1086 6.59E-73 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF53901 694 815 6.59E-73 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF52151 1252 1380 6.54E-50 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF52151 1448 1548 6.54E-50 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF51412 331 590 1.19E-14 T 09-03-2017 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.40.50.720 2195 2228 6.3E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.40.50.720 2274 2452 6.3E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 698 962 4.4E-67 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF51412 16 175 4.58E-13 T 09-03-2017 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.40.47.10 697 974 1.9E-71 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 Gene3D G3DSA:3.40.47.10 975 1137 1.7E-48 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SMART SM00825 Beta-ketoacyl synthase 699 1140 9.9E-101 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF51735 2194 2238 5.67E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SUPERFAMILY SSF51735 2279 2454 5.67E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21900 4de0098c963ebb60b8a493ac2abac622 2476 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2196 2420 7.1E-12 T 09-03-2017 UA74_RS16795 d5492f5e8f1b44cdb805386ae118d2c8 106 Gene3D G3DSA:1.10.287.1060 3 100 7.0E-4 T 09-03-2017 UA74_RS16795 d5492f5e8f1b44cdb805386ae118d2c8 106 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 6 98 1.5E-7 T 09-03-2017 IPR022536 ESX-1 secretion-associated protein EspC UA74_RS04720 d07c337f8a8f5ffe93b074f42ec3987e 295 SMART SM00481 9 73 9.3E-17 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 UA74_RS04720 d07c337f8a8f5ffe93b074f42ec3987e 295 SUPERFAMILY SSF89550 7 91 4.84E-40 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_RS04720 d07c337f8a8f5ffe93b074f42ec3987e 295 SUPERFAMILY SSF89550 174 277 4.84E-40 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_RS04720 d07c337f8a8f5ffe93b074f42ec3987e 295 Gene3D G3DSA:3.20.20.140 166 265 7.9E-34 T 09-03-2017 UA74_RS04720 d07c337f8a8f5ffe93b074f42ec3987e 295 Gene3D G3DSA:3.20.20.140 7 96 7.9E-34 T 09-03-2017 UA74_RS04720 d07c337f8a8f5ffe93b074f42ec3987e 295 Pfam PF02811 PHP domain 10 87 2.0E-6 T 09-03-2017 IPR004013 PHP domain GO:0003824 UA74_RS09065 c4a0e9268a26b69303d20eed0625210e 368 SMART SM00729 117 342 0.0064 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS09065 c4a0e9268a26b69303d20eed0625210e 368 PIRSF PIRSF006004 13 368 1.2E-119 T 09-03-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09065 c4a0e9268a26b69303d20eed0625210e 368 SUPERFAMILY SSF102114 115 339 2.09E-19 T 09-03-2017 UA74_RS09065 c4a0e9268a26b69303d20eed0625210e 368 Pfam PF04055 Radical SAM superfamily 122 295 2.1E-24 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS09065 c4a0e9268a26b69303d20eed0625210e 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 366 7.7E-98 T 09-03-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09065 c4a0e9268a26b69303d20eed0625210e 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 368 65.835 T 09-03-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS09065 c4a0e9268a26b69303d20eed0625210e 368 Gene3D G3DSA:3.20.20.70 118 341 1.8E-19 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 SUPERFAMILY SSF53955 55 274 2.7E-68 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 Pfam PF03793 PASTA domain 706 762 7.4E-9 T 09-03-2017 IPR005543 PASTA domain UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 Gene3D G3DSA:1.10.3810.10 68 256 9.3E-69 T 09-03-2017 UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 SMART SM00740 699 762 1.4E-6 T 09-03-2017 IPR005543 PASTA domain UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 631 3.3E-20 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 Gene3D G3DSA:3.40.710.10 257 691 5.0E-77 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 Pfam PF00912 Transglycosylase 71 253 6.4E-59 T 09-03-2017 IPR001264 Glycosyl transferase, family 51 UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 SUPERFAMILY SSF56601 293 492 3.09E-70 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 SUPERFAMILY SSF56601 522 696 3.09E-70 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS01155 176f4fda305558fa427bbdf96f8ee628 850 SUPERFAMILY SSF56601 235 257 3.09E-70 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 SMART SM00959 52 94 1.8E-9 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 SMART SM00357 308 375 1.1E-6 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 Gene3D G3DSA:3.40.50.300 388 670 4.2E-93 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 SUPERFAMILY SSF68912 53 89 5.89E-5 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 413 617 8.0E-22 T 09-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 SMART SM00382 424 609 1.5E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 Hamap MF_01884 Transcription termination factor Rho [rho]. 300 673 191.981 T 09-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 SUPERFAMILY SSF52540 344 625 9.56E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 Pfam PF07497 Rho termination factor, RNA-binding domain 307 382 1.0E-28 T 09-03-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 TIGRFAM TIGR00767 rho: transcription termination factor Rho 52 671 4.1E-192 T 09-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 Gene3D G3DSA:2.40.50.140 302 382 2.9E-39 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 Gene3D G3DSA:2.40.50.140 53 92 2.9E-39 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS07090 f8009baedd063731eea4eb032208c4d2 680 Pfam PF07498 Rho termination factor, N-terminal domain 53 89 2.4E-10 T 09-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 UA74_RS28040 7b6a05529ed714535a6614e5d1b2a314 334 PIRSF PIRSF016838 3 330 6.3E-18 T 09-03-2017 IPR028349 Protein PafC UA74_RS28040 7b6a05529ed714535a6614e5d1b2a314 334 Pfam PF08279 HTH domain 12 67 4.5E-16 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS28040 7b6a05529ed714535a6614e5d1b2a314 334 SUPERFAMILY SSF46785 9 68 1.27E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28040 7b6a05529ed714535a6614e5d1b2a314 334 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS28040 7b6a05529ed714535a6614e5d1b2a314 334 Pfam PF13280 WYL domain 147 324 3.5E-26 T 09-03-2017 IPR026881 WYL domain UA74_RS28040 7b6a05529ed714535a6614e5d1b2a314 334 Gene3D G3DSA:1.10.10.10 7 70 5.9E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01845 41a1b3e17bce8968c799e377046846a2 381 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 9 316 1.1E-20 T 09-03-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 UA74_RS01845 41a1b3e17bce8968c799e377046846a2 381 SUPERFAMILY SSF53067 122 317 1.64E-32 T 09-03-2017 UA74_RS01845 41a1b3e17bce8968c799e377046846a2 381 SUPERFAMILY SSF53067 7 118 2.59E-14 T 09-03-2017 UA74_RS01845 41a1b3e17bce8968c799e377046846a2 381 Gene3D G3DSA:3.30.420.40 6 78 9.4E-5 T 09-03-2017 UA74_RS18990 07012f3ebb82ffe27636134364389a17 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 3 80 7.0E-11 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS18990 07012f3ebb82ffe27636134364389a17 147 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 3 133 2.1E-34 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS18990 07012f3ebb82ffe27636134364389a17 147 SUPERFAMILY SSF50475 3 135 1.18E-31 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS18990 07012f3ebb82ffe27636134364389a17 147 Gene3D G3DSA:2.30.110.10 3 138 2.2E-25 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 Gene3D G3DSA:3.40.50.1820 8 319 6.0E-61 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 SUPERFAMILY SSF53474 3 319 7.54E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 310 6.9E-92 T 09-03-2017 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.1E-13 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 1.1E-13 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.1E-13 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PIRSF PIRSF006431 1 323 7.2E-113 T 09-03-2017 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 Pfam PF00561 alpha/beta hydrolase fold 35 303 8.3E-34 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 4.9E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 4.9E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS18090 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 4.9E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS10760 2f61c44bffd795e647a38692490e06a8 187 Gene3D G3DSA:2.40.380.10 8 171 2.4E-60 T 09-03-2017 IPR007295 Domain of unknown function DUF402 UA74_RS10760 2f61c44bffd795e647a38692490e06a8 187 SUPERFAMILY SSF159234 12 173 6.28E-40 T 09-03-2017 UA74_RS10760 2f61c44bffd795e647a38692490e06a8 187 Pfam PF04167 Protein of unknown function (DUF402) 60 127 1.3E-9 T 09-03-2017 IPR007295 Domain of unknown function DUF402 UA74_RS19800 09635768c5a77479701566665c092206 509 Gene3D G3DSA:3.40.50.720 5 185 1.2E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19800 09635768c5a77479701566665c092206 509 SUPERFAMILY SSF51735 3 183 5.39E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19800 09635768c5a77479701566665c092206 509 SUPERFAMILY SSF48179 415 498 5.02E-12 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS19800 09635768c5a77479701566665c092206 509 SUPERFAMILY SSF48179 183 285 1.28E-22 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS19800 09635768c5a77479701566665c092206 509 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 417 498 3.8E-11 T 09-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 UA74_RS19800 09635768c5a77479701566665c092206 509 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 184 280 1.0E-20 T 09-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 UA74_RS19800 09635768c5a77479701566665c092206 509 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3 182 9.7E-52 T 09-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 UA74_RS19800 09635768c5a77479701566665c092206 509 Gene3D G3DSA:1.10.1040.10 417 493 7.0E-13 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS19800 09635768c5a77479701566665c092206 509 Gene3D G3DSA:1.10.1040.10 186 280 5.9E-21 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS11785 d51cfb0a3665258738f39d814d8d1c63 319 SUPERFAMILY SSF53756 8 310 6.91E-55 T 09-03-2017 UA74_RS11785 d51cfb0a3665258738f39d814d8d1c63 319 Gene3D G3DSA:3.40.50.2000 10 111 1.5E-8 T 09-03-2017 UA74_RS11785 d51cfb0a3665258738f39d814d8d1c63 319 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 153 265 6.3E-23 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 UA74_RS11785 d51cfb0a3665258738f39d814d8d1c63 319 Gene3D G3DSA:3.40.50.2000 148 309 4.5E-38 T 09-03-2017 UA74_RS28220 5ffa7203a778b4140c8b7adf547f4b54 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 1.1E-60 T 09-03-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS28220 5ffa7203a778b4140c8b7adf547f4b54 147 SUPERFAMILY SSF52161 4 142 6.8E-59 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_RS28220 5ffa7203a778b4140c8b7adf547f4b54 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 09-03-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 UA74_RS28220 5ffa7203a778b4140c8b7adf547f4b54 147 Pfam PF00572 Ribosomal protein L13 15 138 1.5E-54 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_RS28220 5ffa7203a778b4140c8b7adf547f4b54 147 PIRSF PIRSF002181 2 147 1.3E-50 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_RS28220 5ffa7203a778b4140c8b7adf547f4b54 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 28.709 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_RS28220 5ffa7203a778b4140c8b7adf547f4b54 147 Gene3D G3DSA:3.90.1180.10 3 141 1.2E-62 T 09-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 SUPERFAMILY SSF51445 15 377 1.28E-111 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 Pfam PF02449 Beta-galactosidase 25 393 2.4E-150 T 09-03-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 Gene3D G3DSA:3.40.50.880 406 612 1.0E-63 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 Pfam PF08532 Beta-galactosidase trimerisation domain 407 610 8.1E-62 T 09-03-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 Pfam PF08533 Beta-galactosidase C-terminal domain 622 683 2.0E-6 T 09-03-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 Gene3D G3DSA:3.20.20.80 22 398 1.8E-131 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 PIRSF PIRSF001084 13 685 3.9E-262 T 09-03-2017 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS24310 77aff6e138a50ccaaf9b9c48e84e6803 690 SUPERFAMILY SSF52317 406 610 6.1E-54 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS23450 0869627ea9c7e71b07294dbda485b113 481 Gene3D G3DSA:3.30.43.10 15 102 7.8E-8 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS23450 0869627ea9c7e71b07294dbda485b113 481 SUPERFAMILY SSF56176 15 217 3.92E-46 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS23450 0869627ea9c7e71b07294dbda485b113 481 Gene3D G3DSA:3.30.465.10 106 216 1.1E-11 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS23450 0869627ea9c7e71b07294dbda485b113 481 Pfam PF01565 FAD binding domain 52 185 2.1E-25 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS23450 0869627ea9c7e71b07294dbda485b113 481 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 52 85 - T 09-03-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 UA74_RS23450 0869627ea9c7e71b07294dbda485b113 481 Pfam PF08031 Berberine and berberine like 433 466 6.2E-7 T 09-03-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 22 971 24.955 T 09-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 31 965 0.0 T 09-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 Gene3D G3DSA:3.40.640.10 517 754 4.3E-41 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 SUPERFAMILY SSF53383 944 967 8.11E-97 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 SUPERFAMILY SSF53383 476 903 8.11E-97 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 Pfam PF02347 Glycine cleavage system P-protein 461 750 5.6E-13 T 09-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 Pfam PF02347 Glycine cleavage system P-protein 30 456 3.1E-169 T 09-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 Gene3D G3DSA:3.40.640.10 110 321 1.5E-9 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS11480 d7ad733a4054b31fc38703dbbcffc6cc 973 SUPERFAMILY SSF53383 31 456 3.97E-99 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 SUPERFAMILY SSF55920 1 254 3.01E-70 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 9.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 9.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 9.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 9.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 253 2.3E-74 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 Gene3D G3DSA:3.90.230.10 3 254 7.1E-73 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 Pfam PF00557 Metallopeptidase family M24 12 246 1.9E-40 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS11900 6d9b28eac78b3839c0b3f5824d8b8437 255 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 35.227 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 Gene3D G3DSA:3.20.20.450 419 673 1.3E-99 T 09-03-2017 IPR001633 EAL domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 Gene3D G3DSA:3.30.450.20 105 231 4.4E-28 T 09-03-2017 UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 SMART SM00086 191 233 3.8E-5 T 09-03-2017 IPR001610 PAC motif UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 Gene3D G3DSA:3.30.70.270 246 411 2.4E-48 T 09-03-2017 UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 SMART SM00091 118 184 5.6E-10 T 09-03-2017 IPR000014 PAS domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 SMART SM00267 233 405 2.2E-52 T 09-03-2017 IPR000160 GGDEF domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 Pfam PF00990 Diguanylate cyclase, GGDEF domain 244 400 2.5E-39 T 09-03-2017 IPR000160 GGDEF domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 SUPERFAMILY SSF141868 424 672 9.42E-82 T 09-03-2017 IPR001633 EAL domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 SMART SM00052 415 666 1.4E-113 T 09-03-2017 IPR001633 EAL domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 Pfam PF08448 PAS fold 130 235 2.5E-14 T 09-03-2017 IPR013656 PAS fold-4 UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 241 403 5.3E-34 T 09-03-2017 IPR000160 GGDEF domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 Pfam PF00563 EAL domain 424 661 1.7E-70 T 09-03-2017 IPR001633 EAL domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 SUPERFAMILY SSF55073 249 407 2.75E-41 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 114 240 1.6E-26 T 09-03-2017 IPR000014 PAS domain UA74_RS29410 99ca6e38729bd8580f9f8b66e4cf070c 677 SUPERFAMILY SSF55785 105 231 7.25E-27 T 09-03-2017 IPR000014 PAS domain UA74_RS22870 3e62aee869f080d77890cced1390e2ff 237 Pfam PF13476 AAA domain 27 66 7.8E-7 T 09-03-2017 UA74_RS22870 3e62aee869f080d77890cced1390e2ff 237 SMART SM00382 34 212 9.0E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22870 3e62aee869f080d77890cced1390e2ff 237 SUPERFAMILY SSF52540 28 209 1.47E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22870 3e62aee869f080d77890cced1390e2ff 237 Gene3D G3DSA:3.40.50.300 29 69 4.7E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22870 3e62aee869f080d77890cced1390e2ff 237 Gene3D G3DSA:3.40.50.300 123 213 6.1E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17235 f6b5434d2ec1c1733e0926d1619505c6 346 Pfam PF01497 Periplasmic binding protein 75 295 5.9E-16 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS17235 f6b5434d2ec1c1733e0926d1619505c6 346 SUPERFAMILY SSF53807 40 343 7.06E-31 T 09-03-2017 UA74_RS17235 f6b5434d2ec1c1733e0926d1619505c6 346 Gene3D G3DSA:3.40.50.1980 59 205 1.1E-8 T 09-03-2017 UA74_RS17235 f6b5434d2ec1c1733e0926d1619505c6 346 Gene3D G3DSA:3.40.50.1980 210 345 2.2E-13 T 09-03-2017 UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 SUPERFAMILY SSF51445 134 468 1.77E-130 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 SUPERFAMILY SSF51445 497 573 1.77E-130 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 Gene3D G3DSA:2.60.40.10 15 148 1.8E-24 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 SUPERFAMILY SSF81296 15 144 1.22E-18 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 Gene3D G3DSA:2.60.40.1180 587 687 1.1E-17 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 Gene3D G3DSA:3.20.20.80 149 573 5.9E-125 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 Pfam PF00128 Alpha amylase, catalytic domain 173 274 7.3E-11 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 Pfam PF00128 Alpha amylase, catalytic domain 307 528 1.8E-4 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 19 109 1.1E-4 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 SMART SM00642 155 565 7.3E-10 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07705 8363ae400ba99ea1f614b669631fb9c4 695 SUPERFAMILY SSF51011 587 688 1.8E-16 T 09-03-2017 UA74_RS18670 6dc4f2b62ddabbd76e9adaa7cbae1d3f 158 SUPERFAMILY SSF54637 5 139 2.7E-23 T 09-03-2017 IPR029069 HotDog domain UA74_RS18670 6dc4f2b62ddabbd76e9adaa7cbae1d3f 158 Pfam PF13279 Thioesterase-like superfamily 11 135 2.8E-8 T 09-03-2017 UA74_RS18670 6dc4f2b62ddabbd76e9adaa7cbae1d3f 158 Gene3D G3DSA:3.10.129.10 4 139 3.5E-26 T 09-03-2017 IPR029069 HotDog domain UA74_RS12475 015ce557b2d5f1cedd9b8dc2e9b627b2 117 Pfam PF01494 FAD binding domain 11 77 2.0E-29 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS12475 015ce557b2d5f1cedd9b8dc2e9b627b2 117 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 34 50 9.0E-20 T 09-03-2017 UA74_RS12475 015ce557b2d5f1cedd9b8dc2e9b627b2 117 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 52 70 9.0E-20 T 09-03-2017 UA74_RS12475 015ce557b2d5f1cedd9b8dc2e9b627b2 117 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 34 9.0E-20 T 09-03-2017 UA74_RS12475 015ce557b2d5f1cedd9b8dc2e9b627b2 117 SUPERFAMILY SSF51905 11 84 3.98E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12475 015ce557b2d5f1cedd9b8dc2e9b627b2 117 Gene3D G3DSA:3.50.50.60 13 80 4.3E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 Gene3D G3DSA:1.10.40.30 413 472 5.1E-22 T 09-03-2017 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 SUPERFAMILY SSF48557 15 470 1.27E-141 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00145 Argininosuccinate lyase family signature 180 200 1.4E-6 T 09-03-2017 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00145 Argininosuccinate lyase family signature 138 160 1.4E-6 T 09-03-2017 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00145 Argininosuccinate lyase family signature 322 338 1.4E-6 T 09-03-2017 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 Hamap MF_00743 Fumarate hydratase class II [fumC]. 15 472 80.766 T 09-03-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 Pfam PF10415 Fumarase C C-terminus 413 471 7.2E-22 T 09-03-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 Gene3D G3DSA:1.20.200.10 144 408 8.2E-95 T 09-03-2017 UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 Pfam PF00206 Lyase 23 347 2.1E-98 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 Gene3D G3DSA:1.10.275.10 14 143 4.1E-51 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 1.0E-32 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 322 338 1.0E-32 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 185 203 1.0E-32 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 1.0E-32 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS04125 c077734e7bf3b7fcecadd9b340bad0fc 474 ProSitePatterns PS00163 Fumarate lyases signature. 322 331 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00825 Beta-ketoacyl synthase 36 458 9.2E-212 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00825 Beta-ketoacyl synthase 1659 2083 9.6E-224 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.47.10 1920 2081 2.1E-66 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.47.10 295 457 2.1E-63 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 405 1.4E-44 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1915 2030 2.4E-45 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF08990 Erythronolide synthase docking 3 26 6.1E-7 T 09-03-2017 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 2963 3188 8.7E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.366.10 2195 2314 1.2E-69 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.366.10 2380 2490 1.2E-69 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.366.10 548 666 6.2E-62 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.366.10 729 822 6.2E-62 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF53901 31 402 5.92E-102 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 1305 1494 1.0E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF08659 KR domain 2965 3138 8.6E-55 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF08659 KR domain 1308 1478 8.7E-55 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 1163 1293 1.71E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:1.10.1200.10 1563 1638 2.3E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:1.10.1200.10 3224 3297 3.3E-20 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF52151 2381 2476 3.4E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF52151 2195 2320 3.4E-65 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF52151 549 672 6.02E-61 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF52151 731 812 6.02E-61 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM01294 1567 1634 6.5E-6 T 09-03-2017 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM01294 3228 3294 2.7E-4 T 09-03-2017 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00550 Phosphopantetheine attachment site 1569 1634 1.2E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00550 Phosphopantetheine attachment site 3229 3294 6.2E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF55048 2318 2380 2.75E-12 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3253 3268 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.50.720 2964 3142 8.4E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.50.720 1307 1506 3.6E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00975 Thioesterase domain 3364 3570 3.0E-24 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1593 1608 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 552 819 3.0E-82 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2198 2490 8.8E-109 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF14765 Polyketide synthase dehydratase 884 1152 9.2E-60 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF14765 Polyketide synthase dehydratase 2555 2823 1.4E-58 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF53901 1654 2027 5.51E-108 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF47336 1562 1671 2.75E-24 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF55048 671 729 7.72E-6 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00698 Acyl transferase domain 552 790 5.1E-40 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00698 Acyl transferase domain 2197 2509 2.7E-84 T 09-03-2017 IPR014043 Acyl transferase UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.30.70.250 2320 2379 2.0E-6 T 09-03-2017 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 2824 2954 2.76E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.47.10 36 294 4.6E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.47.10 1654 1919 5.3E-90 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 282 4.4E-88 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1657 1907 7.5E-90 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00823 Phosphopantetheine attachment site 1566 1638 1.2E-29 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00823 Phosphopantetheine attachment site 3226 3298 2.6E-26 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00824 Thioesterase 3365 3574 2.3E-106 T 09-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF53474 3256 3294 6.46E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF53474 3340 3575 6.46E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1820 1836 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2965 3139 7.9E-59 T 09-03-2017 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1306 1479 4.3E-48 T 09-03-2017 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.50.1820 3309 3575 2.3E-74 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 534 2.6E-12 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2033 2151 2.7E-12 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00826 2555 2713 3.4E-78 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS17345 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00826 884 1046 7.1E-74 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 SUPERFAMILY SSF53613 238 496 3.27E-51 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 Gene3D G3DSA:3.40.50.10260 4 245 1.3E-54 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 239 500 18.545 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 227 19.066 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 SUPERFAMILY SSF64153 4 260 3.66E-44 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 438 448 - T 09-03-2017 IPR017953 Carbohydrate kinase, predicted, conserved site UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 Gene3D G3DSA:3.40.1190.20 246 497 5.0E-76 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 253 479 3.1E-42 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 Pfam PF03853 YjeF-related protein N-terminus 25 206 9.1E-35 T 09-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 PIRSF PIRSF017184 3 500 9.8E-91 T 09-03-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 UA74_RS28165 e4f331b6148d7694040c0b24d266352f 503 Pfam PF01256 Carbohydrate kinase 262 481 2.0E-50 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_RS09070 d9785c6878e90df36c42b054d6203c5b 161 SMART SM00947 23 161 2.7E-27 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS09070 d9785c6878e90df36c42b054d6203c5b 161 SUPERFAMILY SSF53056 2 160 1.83E-35 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS09070 d9785c6878e90df36c42b054d6203c5b 161 Gene3D G3DSA:3.40.1050.10 4 160 7.7E-34 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS09070 d9785c6878e90df36c42b054d6203c5b 161 Pfam PF00484 Carbonic anhydrase 31 134 1.5E-12 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS07990 0b5edaf4cef42dff2ce179bb01ea4d47 127 Gene3D G3DSA:1.10.490.10 4 125 7.2E-44 T 09-03-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UA74_RS07990 0b5edaf4cef42dff2ce179bb01ea4d47 127 Pfam PF01152 Bacterial-like globin 6 122 9.7E-36 T 09-03-2017 IPR001486 Truncated hemoglobin GO:0019825 UA74_RS07990 0b5edaf4cef42dff2ce179bb01ea4d47 127 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 53 77 - T 09-03-2017 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 UA74_RS07990 0b5edaf4cef42dff2ce179bb01ea4d47 127 SUPERFAMILY SSF46458 6 125 4.93E-36 T 09-03-2017 IPR009050 Globin-like UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 Pfam PF03704 Bacterial transcriptional activator domain 103 248 5.0E-43 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 Gene3D G3DSA:1.25.40.10 110 224 7.7E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 SUPERFAMILY SSF46894 4 95 8.79E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 PRINTS PR00364 Disease resistance protein signature 316 331 9.9E-10 T 09-03-2017 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 PRINTS PR00364 Disease resistance protein signature 477 491 9.9E-10 T 09-03-2017 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 PRINTS PR00364 Disease resistance protein signature 392 406 9.9E-10 T 09-03-2017 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 Pfam PF00931 NB-ARC domain 314 492 1.1E-8 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 SUPERFAMILY SSF52540 280 493 5.35E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 SUPERFAMILY SSF48452 101 264 8.53E-35 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 Gene3D G3DSA:3.40.50.300 281 326 9.5E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 Gene3D G3DSA:1.10.10.10 12 99 7.2E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 Gene3D G3DSA:3.40.50.300 327 408 7.6E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 82 3.5E-9 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 SMART SM00862 17 96 1.1E-6 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS10910 189695b3c2c51378afd34b2eb94e74ac 669 SMART SM01043 103 248 1.3E-46 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS28660 43a9b0c2dbaeed81b6ca8ee625863cd4 280 SUPERFAMILY SSF52540 4 221 3.92E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28660 43a9b0c2dbaeed81b6ca8ee625863cd4 280 Pfam PF00005 ABC transporter 24 165 4.7E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS28660 43a9b0c2dbaeed81b6ca8ee625863cd4 280 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS28660 43a9b0c2dbaeed81b6ca8ee625863cd4 280 SMART SM00382 32 214 3.2E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS28660 43a9b0c2dbaeed81b6ca8ee625863cd4 280 Gene3D G3DSA:3.40.50.300 2 211 3.3E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26305 61b8d3b6ab7a126d4c4776585d4163f0 315 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 306 8.6E-65 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS26305 61b8d3b6ab7a126d4c4776585d4163f0 315 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 09-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UA74_RS26305 61b8d3b6ab7a126d4c4776585d4163f0 315 SUPERFAMILY SSF53686 16 312 2.36E-71 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS26305 61b8d3b6ab7a126d4c4776585d4163f0 315 Gene3D G3DSA:3.40.50.1100 75 311 6.8E-54 T 09-03-2017 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 Pfam PF00931 NB-ARC domain 313 495 9.5E-9 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 Gene3D G3DSA:3.40.50.300 290 409 1.9E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 SUPERFAMILY SSF52540 282 502 2.33E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 Gene3D G3DSA:1.25.40.10 110 234 2.7E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 83 1.6E-10 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 SMART SM01043 110 255 5.5E-52 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 PRINTS PR00364 Disease resistance protein signature 313 328 7.4E-6 T 09-03-2017 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 PRINTS PR00364 Disease resistance protein signature 475 489 7.4E-6 T 09-03-2017 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 PRINTS PR00364 Disease resistance protein signature 390 404 7.4E-6 T 09-03-2017 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 SUPERFAMILY SSF46894 2 83 1.93E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 Pfam PF03704 Bacterial transcriptional activator domain 110 255 9.3E-47 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 SUPERFAMILY SSF48452 106 271 5.55E-42 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 SMART SM00862 15 103 8.8E-8 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS10915 688ca94070c68641a26ff2286f58d731 643 Gene3D G3DSA:1.10.10.10 23 84 2.6E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17860 060941b64417fb0e0227906db56897d3 298 SUPERFAMILY SSF51735 1 214 6.78E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17860 060941b64417fb0e0227906db56897d3 298 Pfam PF00106 short chain dehydrogenase 3 117 7.6E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17860 060941b64417fb0e0227906db56897d3 298 Gene3D G3DSA:3.40.50.720 2 209 1.3E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17860 060941b64417fb0e0227906db56897d3 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 5.6E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17860 060941b64417fb0e0227906db56897d3 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 5.6E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17860 060941b64417fb0e0227906db56897d3 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.6E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF00562 RNA polymerase Rpb2, domain 6 633 1047 8.4E-157 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.30.150.10 505 570 8.5E-27 T 09-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF10385 RNA polymerase beta subunit external 1 domain 504 570 1.4E-24 T 09-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 ProSitePatterns PS01166 RNA polymerases beta chain signature. 870 882 - T 09-03-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:3.90.1100.10 356 504 2.9E-144 T 09-03-2017 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:3.90.1100.10 573 627 2.9E-144 T 09-03-2017 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:3.90.1100.10 34 168 2.9E-144 T 09-03-2017 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:3.90.1110.10 170 339 2.7E-65 T 09-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.40.50.150 735 866 9.7E-58 T 09-03-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.40.50.100 630 699 4.7E-27 T 09-03-2017 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 242 844 0.0 T 09-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04561 RNA polymerase Rpb2, domain 2 168 367 1.3E-25 T 09-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.40.270.10 700 727 9.9E-74 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.40.270.10 867 1025 9.9E-74 T 09-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 26 1125 12.252 T 09-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.7E-26 T 09-03-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 SUPERFAMILY SSF64484 25 1135 0.0 T 09-03-2017 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04563 RNA polymerase beta subunit 89 411 9.5E-22 T 09-03-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02850 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04565 RNA polymerase Rpb2, domain 3 426 494 2.9E-28 T 09-03-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Gene3D G3DSA:3.30.420.10 319 515 4.7E-48 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 184 277 6.2E-27 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 ProSitePatterns PS00447 DNA polymerase family A signature. 728 747 - T 09-03-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Gene3D G3DSA:1.10.150.20 198 257 1.7E-25 T 09-03-2017 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 628 650 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 704 717 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 666 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 787 798 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 674 697 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 728 753 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 819 835 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 765 776 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 PRINTS PR00868 DNA-polymerase family A (pol I) signature 849 862 1.2E-75 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Pfam PF00476 DNA polymerase family A 529 899 1.7E-140 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SUPERFAMILY SSF88723 11 182 1.77E-52 T 09-03-2017 IPR029060 PIN domain-like UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 14 182 1.1E-53 T 09-03-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Pfam PF01612 3'-5' exonuclease 353 446 4.0E-5 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Gene3D G3DSA:1.10.150.20 686 792 1.0E-28 T 09-03-2017 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SMART SM00475 13 273 3.4E-137 T 09-03-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SUPERFAMILY SSF47807 183 296 1.79E-29 T 09-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Gene3D G3DSA:3.30.70.370 793 901 2.2E-66 T 09-03-2017 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Gene3D G3DSA:3.30.70.370 637 685 2.2E-66 T 09-03-2017 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SMART SM00279 185 220 2.4E-16 T 09-03-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 TIGRFAM TIGR00593 pola: DNA polymerase I 15 901 1.8E-301 T 09-03-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Gene3D G3DSA:1.20.1060.10 518 636 2.3E-31 T 09-03-2017 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SUPERFAMILY SSF53098 319 491 8.65E-29 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SMART SM00474 314 492 3.2E-12 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SMART SM00482 659 866 1.3E-108 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 Gene3D G3DSA:3.40.50.1010 14 197 1.6E-67 T 09-03-2017 IPR029060 PIN domain-like UA74_RS10705 013fe88bd33e79b8f55f57ab68766638 903 SUPERFAMILY SSF56672 500 900 1.01E-133 T 09-03-2017 UA74_RS23495 5c376166dd49b714110a67ac2ee9529b 655 SUPERFAMILY SSF56112 41 201 1.25E-12 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS23495 5c376166dd49b714110a67ac2ee9529b 655 Gene3D G3DSA:1.10.510.10 132 180 4.9E-8 T 09-03-2017 UA74_RS01295 4a5266c1c74aa6b912dc9d3254af8fc1 141 Pfam PF00472 RF-1 domain 11 136 2.3E-25 T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_RS01295 4a5266c1c74aa6b912dc9d3254af8fc1 141 SUPERFAMILY SSF75620 11 103 5.1E-13 T 09-03-2017 UA74_RS01295 4a5266c1c74aa6b912dc9d3254af8fc1 141 Gene3D G3DSA:3.30.160.200 11 105 1.3E-26 T 09-03-2017 UA74_RS02270 eb450d4a686a7db7563fbd3482c32798 188 Gene3D G3DSA:1.10.1740.10 6 108 4.2E-29 T 09-03-2017 UA74_RS02270 eb450d4a686a7db7563fbd3482c32798 188 Pfam PF04542 Sigma-70 region 2 26 93 4.6E-16 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS02270 eb450d4a686a7db7563fbd3482c32798 188 SUPERFAMILY SSF88659 110 184 3.36E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS02270 eb450d4a686a7db7563fbd3482c32798 188 Pfam PF08281 Sigma-70, region 4 133 179 3.4E-8 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS02270 eb450d4a686a7db7563fbd3482c32798 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 180 7.3E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS02270 eb450d4a686a7db7563fbd3482c32798 188 SUPERFAMILY SSF88946 4 103 2.35E-27 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS02270 eb450d4a686a7db7563fbd3482c32798 188 Gene3D G3DSA:1.10.10.10 123 184 1.3E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05805 908e230a252d04a7131ce74ec3263310 173 Pfam PF07977 FabA-like domain 37 156 2.7E-21 T 09-03-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 UA74_RS05805 908e230a252d04a7131ce74ec3263310 173 Gene3D G3DSA:3.10.129.10 26 160 7.8E-39 T 09-03-2017 IPR029069 HotDog domain UA74_RS05805 908e230a252d04a7131ce74ec3263310 173 SUPERFAMILY SSF54637 30 160 1.82E-34 T 09-03-2017 IPR029069 HotDog domain UA74_RS03270 41fed1b468e58898febb256d0f3dee21 298 Gene3D G3DSA:3.90.550.10 8 280 2.2E-58 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS03270 41fed1b468e58898febb256d0f3dee21 298 Pfam PF00483 Nucleotidyl transferase 10 272 8.3E-28 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_RS03270 41fed1b468e58898febb256d0f3dee21 298 SUPERFAMILY SSF53448 9 288 1.26E-56 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 SUPERFAMILY SSF52540 441 580 7.48E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 SUPERFAMILY SSF52540 10 205 7.48E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Pfam PF00005 ABC transporter 634 870 3.7E-9 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.40.50.300 622 683 2.4E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.40.50.300 489 606 1.3E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.40.50.300 5 90 1.3E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.40.50.300 831 948 2.4E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.20.1580.10 704 830 7.1E-55 T 09-03-2017 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 934 0.0 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.20.1580.10 413 488 4.8E-51 T 09-03-2017 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.20.1580.10 92 130 4.8E-51 T 09-03-2017 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.20.1580.10 255 289 4.8E-51 T 09-03-2017 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.10.8.280 291 412 2.5E-40 T 09-03-2017 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 22.794 T 09-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 SUPERFAMILY SSF52540 625 924 6.12E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.30.1490.20 201 243 5.6E-28 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.30.1490.20 131 154 5.6E-28 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS21775 f61e7fba1d43a20365521fa24b1a6562 950 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS28745 d9115f8898d5c9d2c72b06d27d6ecc35 365 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 09-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UA74_RS28745 d9115f8898d5c9d2c72b06d27d6ecc35 365 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 344 46.309 T 09-03-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS28745 d9115f8898d5c9d2c72b06d27d6ecc35 365 Gene3D G3DSA:3.20.20.70 2 363 1.2E-121 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS28745 d9115f8898d5c9d2c72b06d27d6ecc35 365 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 86 105 - T 09-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UA74_RS28745 d9115f8898d5c9d2c72b06d27d6ecc35 365 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 10 364 3.8E-127 T 09-03-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS28745 d9115f8898d5c9d2c72b06d27d6ecc35 365 Pfam PF01180 Dihydroorotate dehydrogenase 51 346 2.1E-92 T 09-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UA74_RS28745 d9115f8898d5c9d2c72b06d27d6ecc35 365 SUPERFAMILY SSF51395 2 362 1.28E-96 T 09-03-2017 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 Pfam PF11838 ERAP1-like C-terminal domain 534 841 1.7E-61 T 09-03-2017 IPR024571 ERAP1-like C-terminal domain UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 316 3.1E-22 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 3.1E-22 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 3.1E-22 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 267 277 3.1E-22 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 320 332 3.1E-22 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 Gene3D G3DSA:1.10.390.10 314 460 3.0E-42 T 09-03-2017 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 848 0.0 T 09-03-2017 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 Pfam PF01433 Peptidase family M1 105 393 2.1E-70 T 09-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 SUPERFAMILY SSF55486 216 458 1.14E-76 T 09-03-2017 UA74_RS08045 6d6359c82248fd71497b1c1c44cd2d59 852 SUPERFAMILY SSF63737 6 201 1.29E-39 T 09-03-2017 UA74_RS15045 57257af75bbe1526ccd4d7907619cee5 560 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 292 446 2.6E-28 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS15045 57257af75bbe1526ccd4d7907619cee5 560 SUPERFAMILY SSF47203 297 449 2.09E-37 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS15045 57257af75bbe1526ccd4d7907619cee5 560 SUPERFAMILY SSF56645 65 301 1.83E-36 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS15045 57257af75bbe1526ccd4d7907619cee5 560 Gene3D G3DSA:1.20.140.10 283 451 6.5E-39 T 09-03-2017 UA74_RS15045 57257af75bbe1526ccd4d7907619cee5 560 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 187 282 7.8E-15 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS15045 57257af75bbe1526ccd4d7907619cee5 560 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 405 424 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS15045 57257af75bbe1526ccd4d7907619cee5 560 Gene3D G3DSA:2.40.110.10 187 282 1.7E-19 T 09-03-2017 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 SUPERFAMILY SSF53850 71 390 6.79E-87 T 09-03-2017 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 Gene3D G3DSA:3.40.190.10 73 176 3.3E-51 T 09-03-2017 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 Gene3D G3DSA:3.40.190.10 313 356 3.3E-51 T 09-03-2017 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PIRSF PIRSF019574 29 390 4.8E-105 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 Gene3D G3DSA:3.40.190.10 235 312 1.3E-10 T 09-03-2017 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 134 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 149 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 114 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 335 361 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 309 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 183 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 210 229 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 93 3.6E-46 T 09-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_RS09085 d66d18cf90acb0c83aea260d73f9d405 390 Pfam PF13416 Bacterial extracellular solute-binding protein 91 355 3.6E-35 T 09-03-2017 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 Gene3D G3DSA:3.40.50.10490 332 378 6.6E-11 T 09-03-2017 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 Gene3D G3DSA:3.40.50.10490 83 193 2.2E-19 T 09-03-2017 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 Pfam PF00342 Phosphoglucose isomerase 85 289 1.0E-6 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 Gene3D G3DSA:3.40.50.10490 447 526 8.3E-14 T 09-03-2017 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 Gene3D G3DSA:3.40.50.10490 194 297 2.3E-33 T 09-03-2017 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 267 288 8.3E-10 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 193 211 8.3E-10 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 89 108 8.3E-10 T 09-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12500 fd60e1c07cecbe758f496beefcaea4b6 543 SUPERFAMILY SSF53697 26 380 2.22E-71 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 Pfam PF00117 Glutamine amidotransferase class-I 187 367 1.4E-36 T 09-03-2017 IPR017926 Glutamine amidotransferase UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 7 370 9.3E-132 T 09-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 Gene3D G3DSA:3.50.30.20 6 139 5.7E-57 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 253 264 1.9E-11 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 225 234 1.9E-11 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 344 357 1.9E-11 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 Gene3D G3DSA:3.40.50.880 156 370 2.8E-59 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 SUPERFAMILY SSF52021 6 137 2.88E-53 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 133 4.8E-51 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 287 5.3E-32 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 183 197 5.3E-32 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 222 236 5.3E-32 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 295 306 5.3E-32 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 253 269 5.3E-32 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 5 373 44.412 T 09-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 SMART SM01097 5 135 3.2E-82 T 09-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 SUPERFAMILY SSF52317 156 370 9.94E-51 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00097 Anthranilate synthase component II signature 344 357 2.9E-6 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00097 Anthranilate synthase component II signature 253 264 2.9E-6 T 09-03-2017 UA74_RS12295 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00097 Anthranilate synthase component II signature 225 234 2.9E-6 T 09-03-2017 UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 Gene3D G3DSA:3.40.50.300 22 177 1.9E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 Gene3D G3DSA:1.10.8.60 202 252 6.1E-10 T 09-03-2017 UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 Gene3D G3DSA:1.20.272.10 259 357 1.5E-45 T 09-03-2017 UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 Gene3D G3DSA:1.10.3710.10 358 449 2.1E-27 T 09-03-2017 UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 66 170 2.0E-15 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 SUPERFAMILY SSF48019 263 447 5.44E-73 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 Pfam PF12002 MgsA AAA+ ATPase C terminal 278 443 3.0E-70 T 09-03-2017 IPR021886 MgsA AAA+ ATPase C-terminal UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 SUPERFAMILY SSF52540 28 246 1.13E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 SMART SM00382 62 198 1.9E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12090 532a4dc689e8c07d64fe1571973e43b3 455 Pfam PF16193 AAA C-terminal domain 201 277 4.5E-26 T 09-03-2017 IPR032423 AAA ATPase, C-terminal domain UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Pfam PF03466 LysR substrate binding domain 91 293 7.4E-35 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Gene3D G3DSA:3.40.190.10 92 175 2.9E-20 T 09-03-2017 UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.9E-19 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Gene3D G3DSA:3.40.190.10 176 268 3.5E-24 T 09-03-2017 UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Gene3D G3DSA:1.10.10.10 5 82 1.1E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 SUPERFAMILY SSF46785 6 88 1.14E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.8E-9 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.8E-9 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.8E-9 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22720 ea31b5ffc9aacffda0a0b57b97ae9a53 296 SUPERFAMILY SSF53850 92 292 2.53E-30 T 09-03-2017 UA74_RS29060 02cbb07be69447db25462d8033c0a6d0 431 SUPERFAMILY SSF89796 13 403 1.44E-128 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS29060 02cbb07be69447db25462d8033c0a6d0 431 Gene3D G3DSA:3.40.50.10540 13 227 5.5E-106 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS29060 02cbb07be69447db25462d8033c0a6d0 431 Gene3D G3DSA:3.40.50.10540 316 404 5.5E-106 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS29060 02cbb07be69447db25462d8033c0a6d0 431 Pfam PF02515 CoA-transferase family III 16 380 1.2E-121 T 09-03-2017 IPR003673 CoA-transferase family III GO:0003824 UA74_RS29060 02cbb07be69447db25462d8033c0a6d0 431 Gene3D G3DSA:3.30.1540.10 233 315 2.2E-34 T 09-03-2017 UA74_RS06705 6547ca0d47a00f24f01323b1089a8c3c 98 SUPERFAMILY SSF49384 1 96 1.6E-31 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS06705 6547ca0d47a00f24f01323b1089a8c3c 98 Pfam PF00553 Cellulose binding domain 1 96 3.0E-30 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS06705 6547ca0d47a00f24f01323b1089a8c3c 98 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 64 77 - T 09-03-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 UA74_RS06705 6547ca0d47a00f24f01323b1089a8c3c 98 Gene3D G3DSA:2.60.40.290 1 97 5.1E-34 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS06705 6547ca0d47a00f24f01323b1089a8c3c 98 SMART SM00637 1 97 7.4E-34 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS24710 253e51c1700fa576c59eb22cea03f611 175 Gene3D G3DSA:3.40.630.30 50 152 7.1E-15 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS24710 253e51c1700fa576c59eb22cea03f611 175 SUPERFAMILY SSF55729 15 152 6.56E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS24710 253e51c1700fa576c59eb22cea03f611 175 Pfam PF00583 Acetyltransferase (GNAT) family 81 151 7.5E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS13240 94b04582ee3e36dc86f6acec086cd08d 561 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 43 498 6.4E-162 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 UA74_RS13240 94b04582ee3e36dc86f6acec086cd08d 561 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 5 497 4.2E-188 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 UA74_RS13240 94b04582ee3e36dc86f6acec086cd08d 561 ProSitePatterns PS01303 BCCT family of transporters signature. 312 321 - T 09-03-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 SUPERFAMILY SSF46785 2 108 4.1E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 SUPERFAMILY SSF55961 101 261 5.29E-29 T 09-03-2017 UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 117 255 3.7E-19 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 Gene3D G3DSA:3.30.530.20 91 261 2.5E-28 T 09-03-2017 IPR023393 START-like domain UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 Pfam PF12840 Helix-turn-helix domain 2 61 1.2E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 Gene3D G3DSA:1.10.10.10 2 90 7.4E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 1.3E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 1.3E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.3E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22000 9d16340a562f99a91b668be936dbac05 265 SMART SM00418 3 86 4.2E-16 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 SUPERFAMILY SSF51569 6 293 2.93E-66 T 09-03-2017 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 SMART SM01130 4 294 9.3E-61 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 5.1E-11 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 5.1E-11 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 5.1E-11 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 5.1E-11 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 Gene3D G3DSA:3.20.20.70 3 295 9.9E-69 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 Pfam PF00701 Dihydrodipicolinate synthetase family 6 292 7.7E-44 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS19655 2d3ed58ca3a6290255cda069b8067c46 303 PIRSF PIRSF001365 1 300 2.6E-60 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS18250 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 7.3E-12 T 09-03-2017 UA74_RS18250 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 135 150 7.3E-12 T 09-03-2017 UA74_RS18250 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 252 267 7.3E-12 T 09-03-2017 UA74_RS18250 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 Gene3D G3DSA:3.50.50.60 4 159 2.5E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18250 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 Gene3D G3DSA:3.50.50.60 250 288 2.5E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18250 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 SUPERFAMILY SSF51905 5 156 1.61E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18250 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 SUPERFAMILY SSF51905 238 311 1.61E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22560 10ff8cba1245e30914651a76b0d83cf3 503 Gene3D G3DSA:3.90.76.10 46 189 9.2E-42 T 09-03-2017 UA74_RS22560 10ff8cba1245e30914651a76b0d83cf3 503 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 410 8.9E-84 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS22560 10ff8cba1245e30914651a76b0d83cf3 503 PIRSF PIRSF002741 1 497 1.0E-92 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS22560 10ff8cba1245e30914651a76b0d83cf3 503 Gene3D G3DSA:3.40.190.10 190 289 8.5E-36 T 09-03-2017 UA74_RS22560 10ff8cba1245e30914651a76b0d83cf3 503 SUPERFAMILY SSF53850 33 492 3.04E-119 T 09-03-2017 UA74_RS22560 10ff8cba1245e30914651a76b0d83cf3 503 Gene3D G3DSA:3.10.105.10 290 470 3.1E-41 T 09-03-2017 UA74_RS27655 45738bcd92d6ef6a47318d2859030b19 135 Gene3D G3DSA:3.40.140.10 8 133 1.9E-41 T 09-03-2017 UA74_RS27655 45738bcd92d6ef6a47318d2859030b19 135 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 60 100 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UA74_RS27655 45738bcd92d6ef6a47318d2859030b19 135 SUPERFAMILY SSF53927 9 132 7.31E-37 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 UA74_RS27655 45738bcd92d6ef6a47318d2859030b19 135 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 15 105 2.3E-9 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 UA74_RS14560 fa73a4e2d46eb6663d4eff8305931146 228 SUPERFAMILY SSF56214 99 214 6.28E-15 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS14560 fa73a4e2d46eb6663d4eff8305931146 228 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 101 177 1.2E-9 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS14560 fa73a4e2d46eb6663d4eff8305931146 228 PRINTS PR01399 Enterobactin synthetase component D signature 67 85 3.5E-24 T 09-03-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UA74_RS14560 fa73a4e2d46eb6663d4eff8305931146 228 PRINTS PR01399 Enterobactin synthetase component D signature 144 160 3.5E-24 T 09-03-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UA74_RS14560 fa73a4e2d46eb6663d4eff8305931146 228 PRINTS PR01399 Enterobactin synthetase component D signature 37 57 3.5E-24 T 09-03-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UA74_RS14560 fa73a4e2d46eb6663d4eff8305931146 228 Gene3D G3DSA:3.90.470.20 99 176 2.8E-5 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS30145 f0e5ffee57788175299e9ee4ae5b3bc7 816 Gene3D G3DSA:3.40.710.10 285 706 8.1E-71 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS30145 f0e5ffee57788175299e9ee4ae5b3bc7 816 SUPERFAMILY SSF53955 100 300 5.62E-53 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS30145 f0e5ffee57788175299e9ee4ae5b3bc7 816 Pfam PF00905 Penicillin binding protein transpeptidase domain 374 635 1.1E-25 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_RS30145 f0e5ffee57788175299e9ee4ae5b3bc7 816 Pfam PF00912 Transglycosylase 124 283 2.4E-44 T 09-03-2017 IPR001264 Glycosyl transferase, family 51 UA74_RS30145 f0e5ffee57788175299e9ee4ae5b3bc7 816 SUPERFAMILY SSF56601 265 287 3.42E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS30145 f0e5ffee57788175299e9ee4ae5b3bc7 816 SUPERFAMILY SSF56601 318 690 3.42E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS30145 f0e5ffee57788175299e9ee4ae5b3bc7 816 Gene3D G3DSA:1.10.3810.10 123 284 1.6E-49 T 09-03-2017 UA74_RS21740 d9e2fc93c18220cb1e1ada907c4c5c28 414 Pfam PF07804 HipA-like C-terminal domain 238 384 2.1E-28 T 09-03-2017 IPR012893 HipA-like, C-terminal UA74_RS21740 d9e2fc93c18220cb1e1ada907c4c5c28 414 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 9 107 1.1E-15 T 09-03-2017 IPR017508 HipA, N-terminal subdomain 1 UA74_RS21740 d9e2fc93c18220cb1e1ada907c4c5c28 414 Pfam PF13657 HipA N-terminal domain 9 107 5.6E-23 T 09-03-2017 IPR017508 HipA, N-terminal subdomain 1 UA74_RS21740 d9e2fc93c18220cb1e1ada907c4c5c28 414 Pfam PF07805 HipA-like N-terminal domain 139 231 8.9E-18 T 09-03-2017 IPR012894 HipA, N-terminal subdomain 2 UA74_RS06570 ab4042b7e8fe1be58f0c2a53d3920386 419 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 376 1.9E-30 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS06570 ab4042b7e8fe1be58f0c2a53d3920386 419 SUPERFAMILY SSF53901 224 418 6.12E-58 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS06570 ab4042b7e8fe1be58f0c2a53d3920386 419 Gene3D G3DSA:3.40.47.10 270 418 5.1E-50 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS06570 ab4042b7e8fe1be58f0c2a53d3920386 419 SMART SM00825 Beta-ketoacyl synthase 6 419 6.0E-10 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS06570 ab4042b7e8fe1be58f0c2a53d3920386 419 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 253 7.6E-23 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS06570 ab4042b7e8fe1be58f0c2a53d3920386 419 Gene3D G3DSA:3.40.47.10 4 264 3.5E-33 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS06570 ab4042b7e8fe1be58f0c2a53d3920386 419 SUPERFAMILY SSF53901 4 261 5.52E-33 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16885 d7d9388d916c4f701ebce92065491cfb 331 Gene3D G3DSA:3.40.50.150 89 326 1.4E-57 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16885 d7d9388d916c4f701ebce92065491cfb 331 Gene3D G3DSA:1.10.10.10 2 88 1.4E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16885 d7d9388d916c4f701ebce92065491cfb 331 SUPERFAMILY SSF46785 4 80 7.18E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16885 d7d9388d916c4f701ebce92065491cfb 331 SUPERFAMILY SSF53335 88 324 1.8E-45 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16885 d7d9388d916c4f701ebce92065491cfb 331 Pfam PF00891 O-methyltransferase 98 309 1.1E-46 T 09-03-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_RS16885 d7d9388d916c4f701ebce92065491cfb 331 PIRSF PIRSF005739 1 327 3.6E-42 T 09-03-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Pfam PF13538 UvrD-like helicase C-terminal domain 501 556 4.0E-7 T 09-03-2017 IPR027785 UvrD-like helicase C-terminal domain UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 493 559 2.1E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 285 386 2.1E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 SUPERFAMILY SSF52540 500 560 3.19E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 SUPERFAMILY SSF52540 412 472 3.19E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 SUPERFAMILY SSF52540 2 377 3.19E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 3 251 5.9E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 252 284 9.3E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 393 414 9.3E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15780 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Pfam PF00580 UvrD/REP helicase N-terminal domain 193 264 5.0E-15 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS20025 d93ca96493a75cd05973f569c56b6400 252 Pfam PF12697 Alpha/beta hydrolase family 23 227 1.2E-13 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20025 d93ca96493a75cd05973f569c56b6400 252 SUPERFAMILY SSF53474 4 237 4.47E-49 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20025 d93ca96493a75cd05973f569c56b6400 252 Gene3D G3DSA:3.40.50.1820 5 237 5.2E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20025 d93ca96493a75cd05973f569c56b6400 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 2.4E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20025 d93ca96493a75cd05973f569c56b6400 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.4E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20025 d93ca96493a75cd05973f569c56b6400 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.4E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS25820 666b4259bd3c8ea104ecbff57cbc3b96 228 Gene3D G3DSA:1.10.357.10 26 211 4.9E-42 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS25820 666b4259bd3c8ea104ecbff57cbc3b96 228 SUPERFAMILY SSF48498 101 207 1.33E-16 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS25820 666b4259bd3c8ea104ecbff57cbc3b96 228 SUPERFAMILY SSF46689 27 105 1.36E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS25820 666b4259bd3c8ea104ecbff57cbc3b96 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 50 2.6E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS25820 666b4259bd3c8ea104ecbff57cbc3b96 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 2.6E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS25820 666b4259bd3c8ea104ecbff57cbc3b96 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 82 3.4E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS01560 9db0a9999a61ecda6fe3a3d429e02f0f 305 Gene3D G3DSA:1.10.1040.20 185 282 4.4E-30 T 09-03-2017 IPR018931 Domain of unknown function DUF2520 UA74_RS01560 9db0a9999a61ecda6fe3a3d429e02f0f 305 Pfam PF10728 Domain of unknown function (DUF2520) 160 278 5.9E-36 T 09-03-2017 IPR018931 Domain of unknown function DUF2520 UA74_RS01560 9db0a9999a61ecda6fe3a3d429e02f0f 305 Gene3D G3DSA:3.40.50.720 13 182 1.9E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01560 9db0a9999a61ecda6fe3a3d429e02f0f 305 SUPERFAMILY SSF51735 14 182 8.86E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01560 9db0a9999a61ecda6fe3a3d429e02f0f 305 SUPERFAMILY SSF48179 185 284 5.78E-24 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS01560 9db0a9999a61ecda6fe3a3d429e02f0f 305 Pfam PF10727 Rossmann-like domain 6 128 5.9E-45 T 09-03-2017 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain UA74_RS14220 cf917951bc26b1d89d19d610d226b108 404 SUPERFAMILY SSF55931 21 379 1.28E-84 T 09-03-2017 UA74_RS14220 cf917951bc26b1d89d19d610d226b108 404 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 26 303 2.1E-47 T 09-03-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_RS14220 cf917951bc26b1d89d19d610d226b108 404 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 404 70.638 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_RS14220 cf917951bc26b1d89d19d610d226b108 404 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 25 306 2.7E-77 T 09-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_RS27975 ffd981dfeac0036bc09fe00c3cdbd69f 547 Pfam PF00069 Protein kinase domain 12 264 7.8E-49 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS27975 ffd981dfeac0036bc09fe00c3cdbd69f 547 Gene3D G3DSA:1.10.510.10 82 265 2.0E-47 T 09-03-2017 UA74_RS27975 ffd981dfeac0036bc09fe00c3cdbd69f 547 Gene3D G3DSA:3.30.200.20 4 81 7.0E-23 T 09-03-2017 UA74_RS27975 ffd981dfeac0036bc09fe00c3cdbd69f 547 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS27975 ffd981dfeac0036bc09fe00c3cdbd69f 547 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS27975 ffd981dfeac0036bc09fe00c3cdbd69f 547 SUPERFAMILY SSF56112 5 268 2.43E-71 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS27975 ffd981dfeac0036bc09fe00c3cdbd69f 547 SMART SM00220 12 270 8.7E-64 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 Gene3D G3DSA:3.40.50.1770 2 189 6.1E-64 T 09-03-2017 UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 Gene3D G3DSA:3.40.50.1770 190 355 2.0E-23 T 09-03-2017 UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 SUPERFAMILY SSF51735 137 303 1.03E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 365 2.1E-159 T 09-03-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 2.7E-47 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 PIRSF PIRSF000183 1 371 5.8E-159 T 09-03-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 SUPERFAMILY SSF52283 305 359 2.3E-65 T 09-03-2017 UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 SUPERFAMILY SSF52283 1 137 2.3E-65 T 09-03-2017 UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 9.1E-78 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 SMART SM01003 4 137 2.1E-79 T 09-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_RS26440 a0586db09b79514f73f104bc52b56fe5 375 SMART SM01002 149 297 2.2E-80 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_RS03420 6df8fe08c1e06d82804217dd7afeec3a 284 SUPERFAMILY SSF53790 8 227 2.09E-71 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS03420 6df8fe08c1e06d82804217dd7afeec3a 284 Gene3D G3DSA:3.30.950.10 119 231 6.0E-42 T 09-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS03420 6df8fe08c1e06d82804217dd7afeec3a 284 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 10 277 1.3E-60 T 09-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS03420 6df8fe08c1e06d82804217dd7afeec3a 284 Gene3D G3DSA:3.40.1010.10 8 118 3.1E-7 T 09-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS03420 6df8fe08c1e06d82804217dd7afeec3a 284 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 211 2.2E-26 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS03420 6df8fe08c1e06d82804217dd7afeec3a 284 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 9 229 32.831 T 09-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS03420 6df8fe08c1e06d82804217dd7afeec3a 284 PIRSF PIRSF005917 1 282 6.1E-91 T 09-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS20600 1b4d176acaaafec5b8590adbdbfbb5e3 243 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 163 242 1.4E-20 T 09-03-2017 UA74_RS20600 1b4d176acaaafec5b8590adbdbfbb5e3 243 SUPERFAMILY SSF55166 88 241 9.81E-30 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 SUPERFAMILY SSF52151 2 120 1.73E-64 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 SUPERFAMILY SSF52151 182 305 1.73E-64 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 Gene3D G3DSA:3.30.70.250 124 188 1.9E-20 T 09-03-2017 UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 SUPERFAMILY SSF55048 128 180 1.57E-10 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 Gene3D G3DSA:3.40.366.10 2 120 2.2E-50 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 Gene3D G3DSA:3.40.366.10 189 299 2.2E-50 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 Pfam PF00698 Acyl transferase domain 7 285 1.6E-23 T 09-03-2017 IPR014043 Acyl transferase UA74_RS25585 8adc83552d11e6b204bff30f6d833a70 317 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 306 3.0E-15 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS12865 22b4a97a71d0a3ab3a882847ebbf3f5c 212 Gene3D G3DSA:3.40.50.2300 1 117 1.3E-13 T 09-03-2017 UA74_RS12865 22b4a97a71d0a3ab3a882847ebbf3f5c 212 SUPERFAMILY SSF52172 1 126 3.13E-14 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS12865 22b4a97a71d0a3ab3a882847ebbf3f5c 212 Pfam PF00072 Response regulator receiver domain 6 113 7.1E-6 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS12865 22b4a97a71d0a3ab3a882847ebbf3f5c 212 Gene3D G3DSA:1.10.10.10 118 185 1.4E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12865 22b4a97a71d0a3ab3a882847ebbf3f5c 212 SUPERFAMILY SSF46894 133 185 2.21E-6 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 48 276 3.7E-42 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 SUPERFAMILY SSF81336 109 276 5.49E-36 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 Hamap MF_01393 ATP synthase subunit a [atpB]. 35 282 13.52 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 PRINTS PR00123 ATP synthase A subunit signature 115 131 7.2E-16 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 PRINTS PR00123 ATP synthase A subunit signature 262 277 7.2E-16 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 PRINTS PR00123 ATP synthase A subunit signature 200 222 7.2E-16 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 Pfam PF00119 ATP synthase A chain 59 275 9.8E-47 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS07145 fb370275ab2be9c5b49c17832bbd2f83 283 Gene3D G3DSA:1.20.120.220 108 279 2.5E-39 T 09-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 SUPERFAMILY SSF51735 10 248 4.79E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.1E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.1E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.1E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.1E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.1E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.1E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 5.8E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 5.8E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 5.8E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 200 0.0023 T 09-03-2017 UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 Gene3D G3DSA:3.40.50.720 7 249 1.7E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13450 cabdc332dda932994a9e53c80b491743 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 4.6E-62 T 09-03-2017 UA74_RS13405 040f79227d25ac3b13ccd5d18e7a9bc0 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 48 5.7E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS13405 040f79227d25ac3b13ccd5d18e7a9bc0 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 80 95 5.7E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS13405 040f79227d25ac3b13ccd5d18e7a9bc0 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 5.7E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS13405 040f79227d25ac3b13ccd5d18e7a9bc0 124 Gene3D G3DSA:1.10.10.10 13 112 6.1E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13405 040f79227d25ac3b13ccd5d18e7a9bc0 124 SMART SM00418 31 109 3.8E-18 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS13405 040f79227d25ac3b13ccd5d18e7a9bc0 124 Pfam PF12840 Helix-turn-helix domain 33 89 6.1E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13405 040f79227d25ac3b13ccd5d18e7a9bc0 124 SUPERFAMILY SSF46785 20 111 3.58E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 SUPERFAMILY SSF50249 193 311 1.94E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 Gene3D G3DSA:3.30.1490.70 1 22 1.7E-13 T 09-03-2017 UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 Gene3D G3DSA:3.30.1490.70 147 189 1.7E-13 T 09-03-2017 UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 SUPERFAMILY SSF56091 9 189 1.87E-40 T 09-03-2017 UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 Pfam PF04679 ATP dependent DNA ligase C terminal region 209 305 8.7E-26 T 09-03-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 4 311 1.5E-78 T 09-03-2017 IPR014146 DNA ligase D, ligase domain UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 Gene3D G3DSA:2.40.50.140 194 311 3.6E-43 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 Gene3D G3DSA:3.30.470.30 23 134 1.3E-28 T 09-03-2017 UA74_RS22445 80b2f0cd8e39232fe36642bdf9400dbe 315 Pfam PF01068 ATP dependent DNA ligase domain 13 189 5.9E-30 T 09-03-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 UA74_RS23990 d3e60bf32a8d9274a6e4c1e5a53c8a9e 259 SMART SM00342 168 252 3.5E-11 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS23990 d3e60bf32a8d9274a6e4c1e5a53c8a9e 259 SUPERFAMILY SSF46689 220 255 4.21E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS23990 d3e60bf32a8d9274a6e4c1e5a53c8a9e 259 Pfam PF12833 Helix-turn-helix domain 174 253 7.2E-16 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS23990 d3e60bf32a8d9274a6e4c1e5a53c8a9e 259 Gene3D G3DSA:1.10.10.60 217 256 3.1E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS23990 d3e60bf32a8d9274a6e4c1e5a53c8a9e 259 Gene3D G3DSA:1.10.10.60 150 206 1.8E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS28790 1edc339ecc21b7b8a0d9da3e04854067 393 Pfam PF00155 Aminotransferase class I and II 30 390 1.6E-63 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS28790 1edc339ecc21b7b8a0d9da3e04854067 393 SUPERFAMILY SSF53383 7 393 5.39E-102 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS28790 1edc339ecc21b7b8a0d9da3e04854067 393 Gene3D G3DSA:3.90.1150.10 261 393 3.0E-27 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS28790 1edc339ecc21b7b8a0d9da3e04854067 393 Gene3D G3DSA:3.40.640.10 46 260 1.1E-70 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS01100 df73b123bc3ad649527784f6d28a12be 141 Gene3D G3DSA:3.30.300.20 46 140 5.2E-37 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS01100 df73b123bc3ad649527784f6d28a12be 141 Pfam PF02566 OsmC-like protein 41 137 1.6E-20 T 09-03-2017 IPR003718 OsmC/Ohr family UA74_RS01100 df73b123bc3ad649527784f6d28a12be 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 138 1.6E-49 T 09-03-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 UA74_RS01100 df73b123bc3ad649527784f6d28a12be 141 Gene3D G3DSA:2.20.25.10 1 43 2.1E-15 T 09-03-2017 UA74_RS01100 df73b123bc3ad649527784f6d28a12be 141 SUPERFAMILY SSF82784 2 138 7.85E-41 T 09-03-2017 IPR003718 OsmC/Ohr family UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 SUPERFAMILY SSF53383 111 469 6.33E-71 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 94 1.0E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 SUPERFAMILY SSF46785 32 98 1.78E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 Gene3D G3DSA:3.90.1150.10 365 471 9.7E-6 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 Gene3D G3DSA:3.40.640.10 150 363 1.1E-53 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 Gene3D G3DSA:1.10.10.10 33 95 2.0E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 Pfam PF00155 Aminotransferase class I and II 150 468 3.0E-22 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 SMART SM00345 35 94 5.6E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 1.4E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS28920 0dfb73f30f74b3f82619412e32ceb738 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 1.4E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 SUPERFAMILY SSF47819 609 687 3.71E-19 T 09-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 SUPERFAMILY SSF52540 9 567 2.13E-132 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:1.10.150.80 618 683 6.7E-11 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 274 3.2E-47 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Pfam PF13361 UvrD-like helicase C-terminal domain 280 402 3.1E-19 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Pfam PF13361 UvrD-like helicase C-terminal domain 437 545 2.3E-22 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 SMART SM00341 615 690 3.8E-7 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:3.40.50.300 10 279 4.0E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Pfam PF00570 HRDC domain 619 684 5.3E-18 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:3.40.50.300 482 567 1.7E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04870 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:3.40.50.300 284 398 1.7E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Gene3D G3DSA:3.90.480.10 334 411 9.5E-47 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Gene3D G3DSA:3.90.480.10 95 163 9.5E-47 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF56014 414 560 3.93E-37 T 09-03-2017 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Gene3D G3DSA:3.30.413.10 415 560 1.5E-36 T 09-03-2017 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF55124 15 165 1.23E-38 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF56014 166 325 2.09E-44 T 09-03-2017 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 166 316 8.8E-37 T 09-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 418 555 1.6E-10 T 09-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 467 483 - T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF55124 334 411 4.74E-17 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 PRINTS PR00397 Sirohaem Fe-binding site signature 418 436 5.6E-10 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 PRINTS PR00397 Sirohaem Fe-binding site signature 467 485 5.6E-10 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Gene3D G3DSA:3.30.413.10 166 317 9.1E-42 T 09-03-2017 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 341 405 2.3E-12 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS24630 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 95 156 4.3E-19 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Gene3D G3DSA:3.40.50.300 14 192 3.7E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Pfam PF12029 Domain of unknown function (DUF3516) 374 829 1.9E-214 T 09-03-2017 IPR021904 Protein of unknown function DUF3516 UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Pfam PF00270 DEAD/DEAH box helicase 33 180 6.0E-10 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Gene3D G3DSA:3.40.50.300 286 371 4.4E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Gene3D G3DSA:3.40.50.300 222 253 4.4E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Pfam PF00271 Helicase conserved C-terminal domain 284 363 5.6E-6 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 SUPERFAMILY SSF52540 46 250 7.53E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 SUPERFAMILY SSF52540 283 375 7.53E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 SMART SM00490 277 363 1.7E-12 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS11985 dc53c8b96dfd5d8d558e03eabfe66d4b 834 SMART SM00487 27 211 1.2E-15 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS06605 f54e0a2078b5cbed409d5e2442df0adf 550 Pfam PF00092 von Willebrand factor type A domain 348 533 4.1E-10 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS06605 f54e0a2078b5cbed409d5e2442df0adf 550 Gene3D G3DSA:3.40.50.410 348 533 4.9E-15 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS06605 f54e0a2078b5cbed409d5e2442df0adf 550 SMART SM00327 343 537 8.7E-13 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS06605 f54e0a2078b5cbed409d5e2442df0adf 550 SUPERFAMILY SSF53300 348 533 1.63E-23 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS06605 f54e0a2078b5cbed409d5e2442df0adf 550 Pfam PF13531 Bacterial extracellular solute-binding protein 50 299 2.3E-22 T 09-03-2017 UA74_RS01900 e58b0b9c3839f9806237e44a788077d3 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.8E-19 T 09-03-2017 IPR010035 ThiS, thiamine-biosynthesis UA74_RS01900 e58b0b9c3839f9806237e44a788077d3 66 Pfam PF02597 ThiS family 3 66 2.6E-14 T 09-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 UA74_RS01900 e58b0b9c3839f9806237e44a788077d3 66 SUPERFAMILY SSF54285 1 66 5.67E-16 T 09-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UA74_RS01900 e58b0b9c3839f9806237e44a788077d3 66 Gene3D G3DSA:3.10.20.30 1 66 7.1E-23 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS24670 a70670a77787aedc89adc7f37c16bf94 304 SUPERFAMILY SSF161098 96 284 6.67E-30 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24670 a70670a77787aedc89adc7f37c16bf94 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 286 2.6E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24670 a70670a77787aedc89adc7f37c16bf94 304 Gene3D G3DSA:1.10.3720.10 96 293 9.8E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 Gene3D G3DSA:3.40.50.2300 172 304 2.8E-45 T 09-03-2017 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 Gene3D G3DSA:3.40.50.2300 51 171 9.1E-23 T 09-03-2017 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 1.5E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 SMART SM00354 1 68 1.7E-22 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 Pfam PF13377 Periplasmic binding protein-like domain 165 323 6.4E-39 T 09-03-2017 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 SUPERFAMILY SSF47413 1 54 7.88E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 Gene3D G3DSA:1.10.260.40 1 50 4.8E-23 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24255 d80a28f112e706c80be812098907bb08 330 SUPERFAMILY SSF53822 57 327 1.45E-53 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS10070 c820d0bffda3cd54bb5b0dea739040f4 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 7.7E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS16115 606d04272b01faee55d600c0b6286242 420 Pfam PF00501 AMP-binding enzyme 134 335 5.1E-12 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS16115 606d04272b01faee55d600c0b6286242 420 Gene3D G3DSA:3.40.50.980 108 263 3.4E-8 T 09-03-2017 UA74_RS16115 606d04272b01faee55d600c0b6286242 420 SUPERFAMILY SSF56801 107 337 4.58E-20 T 09-03-2017 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 SUPERFAMILY SSF88946 26 161 7.46E-52 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 Gene3D G3DSA:1.10.10.10 164 215 2.5E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 Gene3D G3DSA:1.10.601.10 14 160 4.8E-63 T 09-03-2017 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 SUPERFAMILY SSF88659 164 237 4.36E-17 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 87 312 5.9E-36 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF04539 Sigma-70 region 3 170 246 6.9E-23 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 SUPERFAMILY SSF88659 221 319 4.3E-26 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 115 128 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF04542 Sigma-70 region 2 91 160 5.2E-22 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF04545 Sigma-70, region 4 259 312 9.5E-19 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 263 275 5.0E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 299 310 5.0E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 139 147 5.0E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 284 299 5.0E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 115 128 5.0E-28 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 Gene3D G3DSA:1.10.10.10 254 322 2.8E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 284 310 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08440 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF00140 Sigma-70 factor, region 1.2 26 59 2.0E-13 T 09-03-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS01275 4e8869467dc9145468abf9521ac919d9 131 SUPERFAMILY SSF82607 3 83 3.14E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS01275 4e8869467dc9145468abf9521ac919d9 131 Gene3D G3DSA:3.30.1310.10 6 85 6.1E-5 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS01275 4e8869467dc9145468abf9521ac919d9 131 Pfam PF02575 YbaB/EbfC DNA-binding family 2 84 9.0E-9 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:3.90.700.10 243 349 1.6E-38 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 593 2.2E-40 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 SUPERFAMILY SSF46977 445 593 1.57E-42 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 593 4.4E-248 T 09-03-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 SUPERFAMILY SSF51905 358 436 7.78E-75 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 SUPERFAMILY SSF51905 2 259 7.78E-75 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 Pfam PF00890 FAD binding domain 7 400 6.6E-115 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:3.50.50.60 3 242 9.5E-117 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:3.50.50.60 350 421 9.5E-117 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 6.3E-5 T 09-03-2017 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 6.3E-5 T 09-03-2017 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 SUPERFAMILY SSF56425 236 354 2.09E-40 T 09-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 PIRSF PIRSF000171 1 567 2.4E-45 T 09-03-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 593 1.6E-282 T 09-03-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:4.10.80.40 543 589 1.6E-17 T 09-03-2017 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:1.20.58.100 426 542 2.1E-36 T 09-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27690 eeb27cc1bae19bd72b1b58b1e52e2350 593 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 09-03-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS00145 0254a6c93c61d37aedf2f1813fa72717 152 SUPERFAMILY SSF49879 51 151 2.49E-24 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 UA74_RS00145 0254a6c93c61d37aedf2f1813fa72717 152 Pfam PF00498 FHA domain 80 143 9.2E-15 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS00145 0254a6c93c61d37aedf2f1813fa72717 152 Gene3D G3DSA:2.60.200.20 60 150 1.1E-24 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS00145 0254a6c93c61d37aedf2f1813fa72717 152 SMART SM00240 79 129 2.7E-13 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 Gene3D G3DSA:3.40.640.10 55 311 2.7E-61 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 Gene3D G3DSA:3.90.1150.10 12 54 4.1E-29 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 Gene3D G3DSA:3.90.1150.10 317 410 4.1E-29 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 Pfam PF00202 Aminotransferase class-III 19 408 1.3E-74 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 2 410 2.3E-193 T 09-03-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 412 1.6E-140 T 09-03-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 UA74_RS01810 d46cd62e321c17cd2124fd154dccecbe 417 SUPERFAMILY SSF53383 9 409 8.82E-105 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:1.20.1580.10 262 332 2.8E-31 T 09-03-2017 UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:1.20.1580.10 99 156 2.8E-31 T 09-03-2017 UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:1.20.1580.10 523 640 2.4E-33 T 09-03-2017 UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 SMART SM00382 30 419 1.1 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 SMART SM00382 482 729 0.2 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 SUPERFAMILY SSF52540 12 59 6.54E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 SUPERFAMILY SSF52540 270 424 6.54E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 SUPERFAMILY SSF52540 471 735 4.23E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:1.10.8.280 157 245 3.4E-5 T 09-03-2017 UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:3.40.50.300 333 448 1.6E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:3.40.50.300 9 58 1.6E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:3.40.50.300 457 517 1.3E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16685 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:3.40.50.300 641 759 1.3E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 118 242 6.5E-29 T 09-03-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 137 154 - T 09-03-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 52 254 4.2E-53 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 SUPERFAMILY SSF55347 116 226 3.71E-37 T 09-03-2017 UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 SUPERFAMILY SSF51735 9 142 2.04E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 11 115 3.3E-23 T 09-03-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 Gene3D G3DSA:3.40.50.720 9 131 1.2E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 11 255 28.609 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 PIRSF PIRSF000161 9 256 9.2E-61 T 09-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09490 0820927c6979c56d7a31255ddde6bdba 256 Gene3D G3DSA:3.30.360.10 132 223 5.0E-32 T 09-03-2017 UA74_RS06880 307fa61250f1ee41f640561d42c3f2ee 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 8.6E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06880 307fa61250f1ee41f640561d42c3f2ee 191 SUPERFAMILY SSF46689 2 58 8.03E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06880 307fa61250f1ee41f640561d42c3f2ee 191 Gene3D G3DSA:1.10.357.10 2 186 8.3E-29 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06880 307fa61250f1ee41f640561d42c3f2ee 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.1E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06880 307fa61250f1ee41f640561d42c3f2ee 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.1E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06880 307fa61250f1ee41f640561d42c3f2ee 191 SUPERFAMILY SSF48498 71 187 3.37E-6 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS29740 779744bc77254618407296c94372ef16 324 SUPERFAMILY SSF52540 2 223 1.18E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29740 779744bc77254618407296c94372ef16 324 Pfam PF00005 ABC transporter 18 156 1.3E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS29740 779744bc77254618407296c94372ef16 324 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS29740 779744bc77254618407296c94372ef16 324 SMART SM00382 26 204 5.3E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS29740 779744bc77254618407296c94372ef16 324 Gene3D G3DSA:3.40.50.300 1 222 1.5E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF05000 RNA polymerase Rpb1, domain 4 753 820 7.1E-8 T 09-03-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 5.5E-80 T 09-03-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 SUPERFAMILY SSF64484 5 1255 0.0 T 09-03-2017 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 721 1.2E-25 T 09-03-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1253 0.0 T 09-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1262 9.984 T 09-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:2.40.40.20 424 451 1.9E-38 T 09-03-2017 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:2.40.40.20 492 564 1.9E-38 T 09-03-2017 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF04998 RNA polymerase Rpb1, domain 5 828 1201 2.1E-64 T 09-03-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 467 560 2.2E-28 T 09-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 461 3.4E-8 T 09-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS02855 16d59e6bd17423fa2ff9a0309c3f10aa 1303 SMART SM00663 310 589 6.3E-172 T 09-03-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS14210 880b1d2b085eccf415a34db649ed6a0a 238 Pfam PF02698 DUF218 domain 44 166 1.1E-24 T 09-03-2017 IPR003848 Domain of unknown function DUF218 UA74_RS14210 880b1d2b085eccf415a34db649ed6a0a 238 Gene3D G3DSA:3.40.50.620 38 166 2.8E-17 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 SUPERFAMILY SSF46785 16 100 2.02E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 Gene3D G3DSA:1.10.10.10 16 77 8.6E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 Gene3D G3DSA:1.20.120.530 79 218 1.2E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 76 1.3E-10 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 SMART SM00345 18 76 8.2E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 Pfam PF07729 FCD domain 86 208 5.4E-24 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 SUPERFAMILY SSF48008 82 217 2.3E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS03710 714fbbd6330c083278fbb1b8c65d28a8 234 SMART SM00895 86 210 1.2E-18 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS22030 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 Gene3D G3DSA:1.10.357.10 14 190 6.4E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22030 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS22030 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.4E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22030 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22030 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22030 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 SUPERFAMILY SSF46689 6 89 4.99E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22030 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 SUPERFAMILY SSF48498 84 187 1.43E-10 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS02150 937d7d80a05f06bcddb1e20686f7d076 170 Pfam PF10698 Protein of unknown function (DUF2505) 14 162 8.4E-36 T 09-03-2017 IPR019639 Protein of unknown function DUF2505 UA74_RS14845 267641577304a115832d49b96f0d5f75 653 Gene3D G3DSA:3.30.450.20 115 220 9.1E-15 T 09-03-2017 UA74_RS14845 267641577304a115832d49b96f0d5f75 653 Pfam PF08447 PAS fold 128 215 9.9E-12 T 09-03-2017 IPR013655 PAS fold-3 GO:0005515 UA74_RS14845 267641577304a115832d49b96f0d5f75 653 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 229 389 2.4E-40 T 09-03-2017 IPR000160 GGDEF domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 SUPERFAMILY SSF141868 405 646 3.14E-70 T 09-03-2017 IPR001633 EAL domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 SMART SM00267 222 389 3.9E-53 T 09-03-2017 IPR000160 GGDEF domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 Gene3D G3DSA:3.20.20.450 405 643 7.2E-72 T 09-03-2017 IPR001633 EAL domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 SMART SM00052 399 642 1.9E-66 T 09-03-2017 IPR001633 EAL domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 Pfam PF00990 Diguanylate cyclase, GGDEF domain 235 385 3.3E-39 T 09-03-2017 IPR000160 GGDEF domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 SUPERFAMILY SSF55073 238 391 3.3E-44 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS14845 267641577304a115832d49b96f0d5f75 653 Gene3D G3DSA:3.30.450.20 1 75 5.5E-6 T 09-03-2017 UA74_RS14845 267641577304a115832d49b96f0d5f75 653 Gene3D G3DSA:3.30.70.270 236 392 4.0E-51 T 09-03-2017 UA74_RS14845 267641577304a115832d49b96f0d5f75 653 SUPERFAMILY SSF55785 1 86 5.93E-7 T 09-03-2017 IPR000014 PAS domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 Pfam PF00563 EAL domain 405 637 6.7E-64 T 09-03-2017 IPR001633 EAL domain UA74_RS14845 267641577304a115832d49b96f0d5f75 653 SUPERFAMILY SSF55785 116 220 1.92E-13 T 09-03-2017 IPR000014 PAS domain UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 1.1E-18 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 Gene3D G3DSA:3.40.50.2300 65 180 2.2E-16 T 09-03-2017 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 Pfam PF13377 Periplasmic binding protein-like domain 183 342 3.6E-32 T 09-03-2017 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 SUPERFAMILY SSF53822 83 342 1.96E-56 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 6.0E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 6.0E-6 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 SUPERFAMILY SSF47413 10 68 1.18E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 Gene3D G3DSA:3.40.50.2300 181 342 2.8E-53 T 09-03-2017 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 SMART SM00354 10 80 1.0E-27 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 Gene3D G3DSA:1.10.260.40 9 64 1.2E-24 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28010 a2c4226e38e840024c1415ef602e7434 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 09-03-2017 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.30.470.20 200 398 9.0E-74 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.30.470.20 752 955 8.4E-67 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF56059 128 400 2.3E-101 T 09-03-2017 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF52440 559 681 7.05E-45 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 7.4E-66 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 882 4.5E-36 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 716 730 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.40.50.20 535 668 2.7E-55 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.40.50.1380 959 1095 1.2E-40 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF48108 396 548 4.71E-41 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SMART SM01096 422 545 2.2E-58 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SMART SM00851 977 1064 1.8E-29 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF56059 680 955 1.56E-94 T 09-03-2017 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02142 MGS-like domain 978 1064 5.1E-20 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 545 1.1E-35 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:1.10.1030.10 399 534 2.7E-40 T 09-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF52335 964 1093 8.24E-35 T 09-03-2017 IPR011607 Methylglyoxal synthase-like domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1092 13.239 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.30.1490.20 693 751 4.7E-27 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.30.1490.20 143 199 1.9E-20 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF52440 1 127 1.27E-47 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 845 852 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.40.50.20 3 108 1.1E-43 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 4.7E-61 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 4.7E-61 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 4.7E-61 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 4.7E-61 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 4.7E-61 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 4.7E-61 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 4.7E-61 T 09-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS12300 8f49e842e1580b8697a8f5f026a1155f 1101 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1085 12.98 T 09-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 UA74_RS27715 6fd134ce0c0c9fde8214872ad4a8ad3c 213 SMART SM00458 73 211 4.9E-12 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS27715 6fd134ce0c0c9fde8214872ad4a8ad3c 213 Gene3D G3DSA:2.80.10.50 123 209 2.1E-28 T 09-03-2017 UA74_RS27715 6fd134ce0c0c9fde8214872ad4a8ad3c 213 Gene3D G3DSA:2.80.10.50 76 109 2.8E-7 T 09-03-2017 UA74_RS27715 6fd134ce0c0c9fde8214872ad4a8ad3c 213 SUPERFAMILY SSF50370 76 209 5.67E-41 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS27715 6fd134ce0c0c9fde8214872ad4a8ad3c 213 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 120 198 1.9E-23 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS13880 6560a18544b7fcd7cef9a2911fe98bc9 719 Gene3D G3DSA:3.40.50.300 415 537 3.5E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13880 6560a18544b7fcd7cef9a2911fe98bc9 719 Gene3D G3DSA:3.40.50.300 194 375 8.0E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13880 6560a18544b7fcd7cef9a2911fe98bc9 719 SUPERFAMILY SSF52540 206 537 1.08E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13880 6560a18544b7fcd7cef9a2911fe98bc9 719 SMART SM00487 188 403 0.0016 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS13880 6560a18544b7fcd7cef9a2911fe98bc9 719 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 217 531 5.2E-38 T 09-03-2017 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_RS13880 6560a18544b7fcd7cef9a2911fe98bc9 719 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 3 152 5.0E-19 T 09-03-2017 IPR006483 CRISPR-associated Cas3-HD domain UA74_RS13880 6560a18544b7fcd7cef9a2911fe98bc9 719 Pfam PF00270 DEAD/DEAH box helicase 203 377 3.6E-8 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS23460 88d2185987e000da26d75e28b67396f3 113 SUPERFAMILY SSF46785 6 99 1.89E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23460 88d2185987e000da26d75e28b67396f3 113 SMART SM00418 9 83 3.4E-17 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS23460 88d2185987e000da26d75e28b67396f3 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 1.1E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS23460 88d2185987e000da26d75e28b67396f3 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.1E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS23460 88d2185987e000da26d75e28b67396f3 113 Pfam PF12840 Helix-turn-helix domain 10 65 2.2E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23460 88d2185987e000da26d75e28b67396f3 113 Gene3D G3DSA:1.10.10.10 5 109 5.4E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07415 1a04521f409a71b0f7eef030357643a1 129 SUPERFAMILY SSF55811 10 108 8.53E-17 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS07415 1a04521f409a71b0f7eef030357643a1 129 Pfam PF00293 NUDIX domain 14 107 6.1E-9 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS07415 1a04521f409a71b0f7eef030357643a1 129 Gene3D G3DSA:3.90.79.10 5 122 1.7E-15 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS02190 13e0cbd2c572e0f02da878ecf9a0b7da 495 Pfam PF07690 Major Facilitator Superfamily 27 417 2.3E-53 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS02190 13e0cbd2c572e0f02da878ecf9a0b7da 495 SUPERFAMILY SSF103473 255 467 6.1E-68 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS02190 13e0cbd2c572e0f02da878ecf9a0b7da 495 SUPERFAMILY SSF103473 15 205 6.1E-68 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS02190 13e0cbd2c572e0f02da878ecf9a0b7da 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 420 2.8E-69 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS02190 13e0cbd2c572e0f02da878ecf9a0b7da 495 Gene3D G3DSA:1.20.1250.20 22 206 9.4E-34 T 09-03-2017 UA74_RS02190 13e0cbd2c572e0f02da878ecf9a0b7da 495 Gene3D G3DSA:1.20.1250.20 267 475 3.8E-16 T 09-03-2017 UA74_RS22800 aa10fcd6a5f600a5e34be1085594d90e 136 Pfam PF01042 Endoribonuclease L-PSP 11 133 2.1E-30 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family UA74_RS22800 aa10fcd6a5f600a5e34be1085594d90e 136 SUPERFAMILY SSF55298 5 135 4.71E-37 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS22800 aa10fcd6a5f600a5e34be1085594d90e 136 Gene3D G3DSA:3.30.1330.40 4 135 1.3E-42 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS29985 f89e734db7a876d0cebbfcea86a8a612 550 SUPERFAMILY SSF52540 42 162 3.6E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29985 f89e734db7a876d0cebbfcea86a8a612 550 Gene3D G3DSA:3.40.50.300 214 289 3.4E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29985 f89e734db7a876d0cebbfcea86a8a612 550 Gene3D G3DSA:3.40.50.300 46 163 3.4E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29985 f89e734db7a876d0cebbfcea86a8a612 550 Pfam PF00350 Dynamin family 50 154 4.4E-10 T 09-03-2017 IPR022812 Dynamin superfamily UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 Pfam PF01479 S4 domain 5 48 4.1E-7 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 SMART SM00363 5 72 3.8E-5 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 SUPERFAMILY SSF55174 4 67 1.77E-11 T 09-03-2017 UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 Gene3D G3DSA:3.40.50.150 95 181 9.6E-7 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 Gene3D G3DSA:3.10.290.10 6 94 1.6E-20 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 SUPERFAMILY SSF53335 62 248 1.58E-19 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 PIRSF PIRSF005578 1 270 2.2E-90 T 09-03-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 Pfam PF01728 FtsJ-like methyltransferase 64 247 2.5E-17 T 09-03-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 UA74_RS21605 545a44b486949fd9a4e5642c7851387d 295 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 242 4.1E-57 T 09-03-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 UA74_RS02980 b867dcacb0bbf15515abd3147cec1750 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.806 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_RS02980 b867dcacb0bbf15515abd3147cec1750 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 4.3E-53 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_RS02980 b867dcacb0bbf15515abd3147cec1750 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.0E-56 T 09-03-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 UA74_RS02980 b867dcacb0bbf15515abd3147cec1750 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 09-03-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02980 b867dcacb0bbf15515abd3147cec1750 122 Gene3D G3DSA:2.40.150.20 2 122 8.5E-53 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_RS02980 b867dcacb0bbf15515abd3147cec1750 122 SUPERFAMILY SSF50193 2 122 9.16E-50 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_RS02980 b867dcacb0bbf15515abd3147cec1750 122 SMART SM01374 1 122 3.1E-85 T 09-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_RS06185 daf83819c415556a611b53e8311ecb6f 838 Pfam PF02687 FtsX-like permease family 717 831 4.1E-16 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS06185 daf83819c415556a611b53e8311ecb6f 838 Pfam PF02687 FtsX-like permease family 256 375 1.6E-13 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 4.1E-5 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 4.1E-5 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.1E-5 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 Gene3D G3DSA:3.50.50.60 2 105 1.0E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF51905 148 309 3.02E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00397 Sirohaem Fe-binding site signature 626 644 1.2E-6 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00397 Sirohaem Fe-binding site signature 669 687 1.2E-6 T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PIRSF PIRSF037149 1 825 0.0 T 09-03-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 282 6.0E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 791 0.0 T 09-03-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF04324 BFD-like [2Fe-2S] binding domain 418 466 3.5E-12 T 09-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 669 685 - T 09-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 622 758 1.3E-20 T 09-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 550 612 5.9E-11 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 Gene3D G3DSA:3.30.413.10 622 759 1.1E-35 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF56014 623 797 7.46E-51 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 Gene3D G3DSA:3.50.50.60 106 308 2.2E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.0E-17 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.0E-17 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 6.0E-17 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 6.0E-17 T 09-03-2017 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF51905 2 187 2.64E-41 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09455 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF55124 492 631 4.42E-24 T 09-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 380 3.0E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 361 3.0E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 337 3.0E-7 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 231 1.4E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 275 381 6.8E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 SMART SM00304 113 166 8.4E-8 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 Gene3D G3DSA:1.10.287.130 159 218 1.0E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 SMART SM00388 167 232 1.3E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 Gene3D G3DSA:3.30.565.10 219 384 5.8E-29 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 SUPERFAMILY SSF55874 221 384 7.73E-31 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 Pfam PF00672 HAMP domain 95 162 1.4E-12 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 SUPERFAMILY SSF158472 115 164 4.18E-6 T 09-03-2017 UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 SMART SM00387 275 383 1.3E-24 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07900 a6d77b10da99b6e127cbd0eecd9c059f 400 SUPERFAMILY SSF47384 151 231 4.51E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 Pfam PF04389 Peptidase family M28 253 444 1.1E-36 T 09-03-2017 IPR007484 Peptidase M28 UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 Gene3D G3DSA:3.40.630.10 245 460 8.6E-62 T 09-03-2017 UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 Gene3D G3DSA:3.40.630.10 51 108 8.6E-62 T 09-03-2017 UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 Gene3D G3DSA:3.50.30.30 131 237 2.3E-10 T 09-03-2017 UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 SUPERFAMILY SSF52025 132 222 4.58E-8 T 09-03-2017 UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 Pfam PF02225 PA domain 139 228 2.7E-6 T 09-03-2017 IPR003137 PA domain UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 SUPERFAMILY SSF53187 245 459 9.67E-57 T 09-03-2017 UA74_RS21390 9c083b42b3f558d044e87d3d7a03264a 461 SUPERFAMILY SSF53187 52 108 9.67E-57 T 09-03-2017 UA74_RS06770 8f96a74679dabeb4c90975fc0546b36f 658 Pfam PF03703 Bacterial PH domain 542 614 5.1E-7 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS06770 8f96a74679dabeb4c90975fc0546b36f 658 Pfam PF03703 Bacterial PH domain 185 266 9.4E-17 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS22610 1e3f5b58c1b50a387a2868e611cf663a 382 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 73 211 1.8E-26 T 09-03-2017 UA74_RS22610 1e3f5b58c1b50a387a2868e611cf663a 382 SUPERFAMILY SSF53335 82 209 8.02E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS22610 1e3f5b58c1b50a387a2868e611cf663a 382 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 167 182 - T 09-03-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_RS22610 1e3f5b58c1b50a387a2868e611cf663a 382 Gene3D G3DSA:3.40.50.150 22 243 8.4E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23230 b750172a31856da8793084f62255918d 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS23230 b750172a31856da8793084f62255918d 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.6E-18 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS23230 b750172a31856da8793084f62255918d 214 Gene3D G3DSA:1.10.10.60 11 67 4.2E-21 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS23230 b750172a31856da8793084f62255918d 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 3.0E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS23230 b750172a31856da8793084f62255918d 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 3.0E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS23230 b750172a31856da8793084f62255918d 214 Gene3D G3DSA:1.10.357.10 68 200 6.7E-19 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS23230 b750172a31856da8793084f62255918d 214 SUPERFAMILY SSF46689 11 89 1.02E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS09980 4bc733940a91077426cb571c0928f758 193 Gene3D G3DSA:1.20.120.450 11 191 7.2E-38 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS09980 4bc733940a91077426cb571c0928f758 193 Pfam PF04978 Protein of unknown function (DUF664) 34 189 4.9E-40 T 09-03-2017 IPR007061 Protein of unknown function DUF664 UA74_RS09980 4bc733940a91077426cb571c0928f758 193 SUPERFAMILY SSF109854 19 188 6.87E-35 T 09-03-2017 UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 5.6E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 5.6E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 5.6E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 5.6E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 SMART SM00347 37 140 5.2E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 Gene3D G3DSA:1.10.10.10 8 156 5.9E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 Pfam PF12802 MarR family 43 103 2.8E-10 T 09-03-2017 UA74_RS00730 b08db3495f820b133d90720d8c2cc662 159 SUPERFAMILY SSF46785 6 155 3.05E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 PIRSF PIRSF001594 1 1125 0.0 T 09-03-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1124 0.0 T 09-03-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.30.470.20 205 451 4.0E-100 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF51246 334 451 1.31E-37 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:2.40.50.100 1050 1124 1.5E-19 T 09-03-2017 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 6.4E-40 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.40.50.20 1 130 2.4E-44 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF02436 Conserved carboxylase domain 821 1008 6.3E-52 T 09-03-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 SMART SM00878 339 446 9.9E-55 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF00364 Biotin-requiring enzyme 1066 1124 4.5E-14 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF56059 84 357 1.94E-67 T 09-03-2017 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF00682 HMGL-like 525 797 8.7E-31 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.20.20.70 503 812 1.0E-125 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1081 1098 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.10.600.10 959 1045 2.3E-31 T 09-03-2017 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 1.6E-34 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF89000 826 991 1.14E-38 T 09-03-2017 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF51230 1048 1124 1.7E-16 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.30.1490.20 131 201 2.0E-22 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF52440 1 112 8.63E-41 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF51569 517 829 1.59E-76 T 09-03-2017 UA74_RS25815 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 2.1E-68 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 PRINTS PR00359 B-class P450 signature 194 216 2.5E-9 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 PRINTS PR00359 B-class P450 signature 97 108 2.5E-9 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 PRINTS PR00359 B-class P450 signature 143 159 2.5E-9 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 PRINTS PR00359 B-class P450 signature 335 344 2.5E-9 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 PRINTS PR00359 B-class P450 signature 344 355 2.5E-9 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 Gene3D G3DSA:1.10.630.10 12 397 7.2E-81 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20380 cf2d0d9779dc0c33f2ae0e7ca455217f 465 SUPERFAMILY SSF48264 15 397 2.23E-58 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 Gene3D G3DSA:3.40.50.2300 19 142 1.8E-36 T 09-03-2017 UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 Pfam PF03861 ANTAR domain 152 205 1.4E-22 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 SMART SM01012 150 205 3.4E-25 T 09-03-2017 IPR005561 ANTAR domain GO:0003723 UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 SMART SM00448 23 134 1.2E-34 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 Pfam PF00072 Response regulator receiver domain 25 134 1.3E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 PIRSF PIRSF036382 13 209 3.0E-74 T 09-03-2017 IPR008327 Signal transduction response regulator, antiterminator UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 Gene3D G3DSA:1.10.10.10 152 208 7.4E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10670 113ba3dc952fea3e4b359fa0bbef4b08 209 SUPERFAMILY SSF52172 21 205 2.56E-57 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS14880 026ec8437e00545c796eb40a58e4f2f4 366 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 257 263 - T 09-03-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 UA74_RS14880 026ec8437e00545c796eb40a58e4f2f4 366 Gene3D G3DSA:3.20.20.70 9 355 9.0E-126 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS14880 026ec8437e00545c796eb40a58e4f2f4 366 Pfam PF01070 FMN-dependent dehydrogenase 18 354 3.4E-119 T 09-03-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 UA74_RS14880 026ec8437e00545c796eb40a58e4f2f4 366 SUPERFAMILY SSF51395 9 355 5.98E-84 T 09-03-2017 UA74_RS14880 026ec8437e00545c796eb40a58e4f2f4 366 PIRSF PIRSF000138 1 361 4.3E-120 T 09-03-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 UA74_RS30330 212d4fd078400b02d327dfdc36d6a473 741 SUPERFAMILY SSF82866 121 319 4.32E-30 T 09-03-2017 UA74_RS30330 212d4fd078400b02d327dfdc36d6a473 741 Pfam PF03176 MMPL family 381 677 2.2E-29 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 UA74_RS30330 212d4fd078400b02d327dfdc36d6a473 741 Pfam PF03176 MMPL family 32 351 5.8E-45 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 UA74_RS30330 212d4fd078400b02d327dfdc36d6a473 741 Gene3D G3DSA:1.20.1640.10 131 322 1.4E-29 T 09-03-2017 UA74_RS30330 212d4fd078400b02d327dfdc36d6a473 741 Gene3D G3DSA:1.20.1640.10 455 679 1.3E-31 T 09-03-2017 UA74_RS30330 212d4fd078400b02d327dfdc36d6a473 741 SUPERFAMILY SSF82866 434 674 1.31E-28 T 09-03-2017 UA74_RS24660 c9b0d30744218d6337030e6f6f665175 159 SUPERFAMILY SSF52540 19 158 5.13E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24660 c9b0d30744218d6337030e6f6f665175 159 Pfam PF00005 ABC transporter 38 158 2.5E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS24660 c9b0d30744218d6337030e6f6f665175 159 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS24660 c9b0d30744218d6337030e6f6f665175 159 Gene3D G3DSA:3.40.50.300 13 158 2.4E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 ProSitePatterns PS00855 Signal peptidases II signature. 98 110 - T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 TIGRFAM TIGR00077 lspA: signal peptidase II 11 149 2.3E-23 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 6 152 12.653 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 Pfam PF01252 Signal peptidase (SPase) II 15 146 2.8E-27 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 Pfam PF05449 Putative 3TM holin, Phage_holin_3 50 106 1.1E-5 T 09-03-2017 IPR008473 Putative 3TM holin, Phage holin 3 UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 49 57 2.4E-14 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 127 143 2.4E-14 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS10195 5cbdcca0797396a2cb4f8177a138b512 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 95 110 2.4E-14 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS08190 faf73ee67873224111e64db8588c2fdf 201 SUPERFAMILY SSF53474 5 186 2.48E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08190 faf73ee67873224111e64db8588c2fdf 201 Gene3D G3DSA:3.40.50.1820 3 184 3.6E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08190 faf73ee67873224111e64db8588c2fdf 201 Pfam PF06821 Serine hydrolase 6 184 6.5E-26 T 09-03-2017 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 Gene3D G3DSA:3.30.930.10 125 365 3.2E-119 T 09-03-2017 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 Gene3D G3DSA:3.30.930.10 10 93 3.2E-119 T 09-03-2017 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 SUPERFAMILY SSF55681 7 372 3.55E-98 T 09-03-2017 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 SUPERFAMILY SSF52954 356 461 7.55E-30 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 Pfam PF03129 Anticodon binding domain 369 456 2.6E-18 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 Gene3D G3DSA:3.40.50.800 366 457 8.6E-34 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 2.6E-43 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 2.6E-43 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 2.6E-43 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 2.6E-43 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 2.6E-43 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS24490 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 320 332 2.6E-43 T 09-03-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS27115 01c1996ed90b185c37bf450faa8e34f3 364 SUPERFAMILY SSF50331 243 358 3.4E-10 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS27115 01c1996ed90b185c37bf450faa8e34f3 364 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS27115 01c1996ed90b185c37bf450faa8e34f3 364 SUPERFAMILY SSF52540 3 245 8.57E-81 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27115 01c1996ed90b185c37bf450faa8e34f3 364 Pfam PF08402 TOBE domain 283 358 1.6E-13 T 09-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 UA74_RS27115 01c1996ed90b185c37bf450faa8e34f3 364 Pfam PF00005 ABC transporter 19 166 6.1E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS27115 01c1996ed90b185c37bf450faa8e34f3 364 SMART SM00382 27 216 3.4E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS27115 01c1996ed90b185c37bf450faa8e34f3 364 Gene3D G3DSA:3.40.50.300 3 238 1.6E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 Gene3D G3DSA:3.40.50.20 6 85 3.7E-21 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 SUPERFAMILY SSF52440 6 97 1.25E-21 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 312 27.947 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 Gene3D G3DSA:3.30.470.20 183 311 4.6E-41 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 Gene3D G3DSA:3.30.470.20 86 104 4.6E-41 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 SUPERFAMILY SSF56059 97 308 8.93E-45 T 09-03-2017 UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 Pfam PF01820 D-ala D-ala ligase N-terminus 6 86 2.1E-15 T 09-03-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 Gene3D G3DSA:3.30.1490.20 107 182 2.3E-16 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 Pfam PF07478 D-ala D-ala ligase C-terminus 106 309 5.3E-44 T 09-03-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS30425 fdef1a315fd7a72ce349ffd686496395 315 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 64 75 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS16450 1959b6bb5254eea9a384e406e9934247 334 SUPERFAMILY SSF53098 148 207 2.15E-6 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS16450 1959b6bb5254eea9a384e406e9934247 334 Pfam PF13011 leucine-zipper of insertion element IS481 1 53 1.7E-17 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type UA74_RS16450 1959b6bb5254eea9a384e406e9934247 334 SUPERFAMILY SSF46689 1 82 2.15E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS16450 1959b6bb5254eea9a384e406e9934247 334 Pfam PF00665 Integrase core domain 109 207 4.0E-14 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 UA74_RS16450 1959b6bb5254eea9a384e406e9934247 334 Gene3D G3DSA:3.30.420.10 105 206 9.9E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS06410 789fdd65132a527f35929f531e31da82 130 SMART SM00450 16 120 1.2E-15 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS06410 789fdd65132a527f35929f531e31da82 130 SUPERFAMILY SSF52821 8 126 2.36E-23 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS06410 789fdd65132a527f35929f531e31da82 130 Gene3D G3DSA:3.40.250.10 3 124 6.1E-26 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS06410 789fdd65132a527f35929f531e31da82 130 Pfam PF00581 Rhodanese-like domain 19 116 4.2E-10 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 PRINTS PR01036 Tetracycline resistance protein TetB signature 97 119 3.8E-5 T 09-03-2017 UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 3.8E-5 T 09-03-2017 UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 PRINTS PR01036 Tetracycline resistance protein TetB signature 37 61 3.8E-5 T 09-03-2017 UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 PRINTS PR01036 Tetracycline resistance protein TetB signature 420 439 3.8E-5 T 09-03-2017 UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 SUPERFAMILY SSF103473 21 220 1.96E-66 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 SUPERFAMILY SSF103473 268 439 1.96E-66 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 SUPERFAMILY SSF103473 492 519 1.96E-66 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 Pfam PF07690 Major Facilitator Superfamily 38 429 7.9E-50 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 Gene3D G3DSA:1.20.1250.20 493 522 1.1E-19 T 09-03-2017 UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 Gene3D G3DSA:1.20.1250.20 285 441 1.1E-19 T 09-03-2017 UA74_RS15535 34ee4b10047091f44767b7d77de24b94 527 Gene3D G3DSA:1.20.1250.20 31 214 1.3E-32 T 09-03-2017 UA74_RS13500 e64f8538f75c112b7a2ba42eda3575da 75 Pfam PF04149 Domain of unknown function (DUF397) 11 67 3.4E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS10510 3e7941306f45035e15bd903d385ee3b5 314 Gene3D G3DSA:3.40.50.2000 5 67 1.8E-8 T 09-03-2017 UA74_RS10510 3e7941306f45035e15bd903d385ee3b5 314 SUPERFAMILY SSF53756 4 309 8.48E-57 T 09-03-2017 UA74_RS10510 3e7941306f45035e15bd903d385ee3b5 314 Gene3D G3DSA:3.40.50.2000 146 309 9.5E-45 T 09-03-2017 UA74_RS10510 3e7941306f45035e15bd903d385ee3b5 314 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 152 272 6.6E-28 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 UA74_RS11130 2442b594c7527bafee319adf19061657 206 Pfam PF03551 Transcriptional regulator PadR-like family 14 89 7.3E-13 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS11130 2442b594c7527bafee319adf19061657 206 Gene3D G3DSA:1.10.10.10 6 98 1.0E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11130 2442b594c7527bafee319adf19061657 206 SUPERFAMILY SSF46785 10 187 9.86E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13915 4332d6e2a9a4c93c5d29757ce08478a5 251 Gene3D G3DSA:1.10.1660.10 4 107 8.3E-25 T 09-03-2017 UA74_RS13915 4332d6e2a9a4c93c5d29757ce08478a5 251 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.6E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13915 4332d6e2a9a4c93c5d29757ce08478a5 251 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.6E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13915 4332d6e2a9a4c93c5d29757ce08478a5 251 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.6E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13915 4332d6e2a9a4c93c5d29757ce08478a5 251 Pfam PF13411 MerR HTH family regulatory protein 4 68 2.0E-11 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13915 4332d6e2a9a4c93c5d29757ce08478a5 251 SMART SM00422 3 72 2.0E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13915 4332d6e2a9a4c93c5d29757ce08478a5 251 SUPERFAMILY SSF46955 4 105 5.86E-22 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS22425 7514e179f359a43c261404987d551e47 167 Pfam PF00583 Acetyltransferase (GNAT) family 53 125 2.2E-11 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS22425 7514e179f359a43c261404987d551e47 167 SUPERFAMILY SSF55729 1 130 7.89E-24 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS22425 7514e179f359a43c261404987d551e47 167 Gene3D G3DSA:3.40.630.30 4 127 2.0E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 SUPERFAMILY SSF52317 1 189 5.8E-43 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 Gene3D G3DSA:1.10.10.60 262 309 4.0E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 SUPERFAMILY SSF46689 208 256 6.27E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 Pfam PF12833 Helix-turn-helix domain 229 307 1.0E-20 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 SUPERFAMILY SSF46689 260 309 7.62E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 Pfam PF01965 DJ-1/PfpI family 3 168 3.9E-18 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 Gene3D G3DSA:1.10.10.60 203 261 2.0E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 SMART SM00342 223 306 3.5E-25 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS24405 6e83d6d24f0dcba50cb7264974665ea3 311 Gene3D G3DSA:3.40.50.880 1 189 3.8E-47 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS17805 6df8be07361e6d3124e1d78a5c4e2b1e 282 SUPERFAMILY SSF47413 11 69 7.6E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17805 6df8be07361e6d3124e1d78a5c4e2b1e 282 SMART SM00530 16 71 0.0077 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS17805 6df8be07361e6d3124e1d78a5c4e2b1e 282 Pfam PF13560 Helix-turn-helix domain 13 72 2.9E-6 T 09-03-2017 UA74_RS17805 6df8be07361e6d3124e1d78a5c4e2b1e 282 Gene3D G3DSA:1.10.260.40 3 70 1.2E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 SUPERFAMILY SSF51905 3 307 6.11E-33 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 6.1E-13 T 09-03-2017 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 6.1E-13 T 09-03-2017 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.1E-13 T 09-03-2017 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 287 1.0E-18 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 Gene3D G3DSA:3.50.50.60 5 134 8.4E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 Gene3D G3DSA:3.50.50.60 262 310 8.4E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 Gene3D G3DSA:3.50.50.60 135 234 2.4E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 144 2.9E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.9E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 273 291 2.9E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS15000 398e1b21f28df58255c9d8e03c73f805 348 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 2.9E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS26235 58427b850eaa144d994c66619d44cdea 463 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 211 393 9.5E-18 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS26235 58427b850eaa144d994c66619d44cdea 463 Pfam PF11398 Protein of unknown function (DUF2813) 2 44 6.0E-5 T 09-03-2017 IPR022602 Protein of unknown function DUF2813 UA74_RS26235 58427b850eaa144d994c66619d44cdea 463 SUPERFAMILY SSF52540 255 260 1.87E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26235 58427b850eaa144d994c66619d44cdea 463 SUPERFAMILY SSF52540 305 399 1.87E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26235 58427b850eaa144d994c66619d44cdea 463 SUPERFAMILY SSF52540 2 124 1.87E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26235 58427b850eaa144d994c66619d44cdea 463 Gene3D G3DSA:3.40.50.300 2 159 2.8E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26235 58427b850eaa144d994c66619d44cdea 463 Gene3D G3DSA:3.40.50.300 253 402 2.8E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19810 90377310f4eeacdcdff748a49ef3d457 378 SUPERFAMILY SSF56601 50 367 2.82E-68 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS19810 90377310f4eeacdcdff748a49ef3d457 378 Pfam PF00144 Beta-lactamase 56 375 1.3E-50 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS19810 90377310f4eeacdcdff748a49ef3d457 378 Gene3D G3DSA:3.40.710.10 37 375 3.7E-67 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS28065 9a09ee20b61e444c92da8767a40a7206 132 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 9 122 1.0E-27 T 09-03-2017 UA74_RS01565 d5bb3ca80761a8b3f41ed9248ef56c3b 321 SUPERFAMILY SSF52374 16 293 3.49E-100 T 09-03-2017 UA74_RS01565 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Gene3D G3DSA:3.30.1300.10 191 295 8.6E-30 T 09-03-2017 UA74_RS01565 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Pfam PF02569 Pantoate-beta-alanine ligase 20 288 1.7E-92 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UA74_RS01565 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Gene3D G3DSA:3.40.50.620 15 190 2.7E-73 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS01565 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Hamap MF_00158 Pantothenate synthetase [panC]. 17 290 37.453 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UA74_RS01565 d5bb3ca80761a8b3f41ed9248ef56c3b 321 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 23 290 1.8E-81 T 09-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UA74_RS26635 3674e8b082569c018a27c95002c2bbf7 122 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 11 85 5.3E-28 T 09-03-2017 IPR024020 Anti sigma-R factor, mycothiol system,RsrA UA74_RS26635 3674e8b082569c018a27c95002c2bbf7 122 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 5 82 5.1E-25 T 09-03-2017 IPR014295 Anti-sigma factor UA74_RS07355 fdbcdec48b7c1df5d23a00bea0d9d67c 280 SUPERFAMILY SSF55315 13 109 2.82E-8 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS07355 fdbcdec48b7c1df5d23a00bea0d9d67c 280 Pfam PF00588 SpoU rRNA Methylase family 123 268 1.1E-32 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_RS07355 fdbcdec48b7c1df5d23a00bea0d9d67c 280 Gene3D G3DSA:3.40.1280.10 121 276 4.7E-46 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS07355 fdbcdec48b7c1df5d23a00bea0d9d67c 280 Gene3D G3DSA:3.30.1330.30 14 111 2.9E-24 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS07355 fdbcdec48b7c1df5d23a00bea0d9d67c 280 SUPERFAMILY SSF75217 116 277 1.11E-38 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 SUPERFAMILY SSF47384 212 295 3.73E-16 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 SMART SM00388 229 294 9.8E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 Gene3D G3DSA:1.10.287.130 222 279 8.3E-13 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 SMART SM00387 334 444 2.6E-26 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 1.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 1.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 1.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 1.3E-12 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 SUPERFAMILY SSF55874 284 442 1.96E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 294 5.4E-13 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 442 1.4E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS04385 73f8da7de50097f9898ab97e6eeb6bea 444 Gene3D G3DSA:3.30.565.10 280 442 5.3E-31 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 Pfam PF10502 Signal peptidase, peptidase S26 144 261 1.8E-7 T 09-03-2017 IPR019533 Peptidase S26 UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 Pfam PF00717 Peptidase S24-like 86 132 2.9E-6 T 09-03-2017 IPR019759 Peptidase S24/S26A/S26B UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 SUPERFAMILY SSF51306 162 270 7.85E-43 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 SUPERFAMILY SSF51306 78 130 7.85E-43 T 09-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 95 2.2E-18 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 167 179 2.2E-18 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 218 237 2.2E-18 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 Gene3D G3DSA:2.10.109.10 161 177 2.1E-37 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 Gene3D G3DSA:2.10.109.10 218 273 2.1E-37 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 Gene3D G3DSA:2.10.109.10 75 129 2.1E-37 T 09-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 66 263 1.9E-36 T 09-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_RS08950 4fb2b1733dd05306d43e167cde6c8cdd 315 ProSitePatterns PS00761 Signal peptidases I signature 3. 223 236 - T 09-03-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 Pfam PF02562 PhoH-like protein 262 466 5.6E-53 T 09-03-2017 IPR003714 PhoH-like protein GO:0005524 UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 SMART SM00670 45 172 3.7E-19 T 09-03-2017 IPR002716 PIN domain UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 SUPERFAMILY SSF52540 260 422 3.56E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 Gene3D G3DSA:3.40.50.1010 46 104 6.4E-11 T 09-03-2017 IPR029060 PIN domain-like UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 Gene3D G3DSA:3.40.50.1010 137 180 6.4E-11 T 09-03-2017 IPR029060 PIN domain-like UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 Gene3D G3DSA:3.40.50.300 261 466 7.8E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 Pfam PF13638 PIN domain 47 185 3.6E-27 T 09-03-2017 IPR002716 PIN domain UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 SUPERFAMILY SSF88723 137 179 4.07E-9 T 09-03-2017 IPR029060 PIN domain-like UA74_RS04100 2b743075ea924da0330267e3fdbced98 472 SUPERFAMILY SSF88723 46 104 4.07E-9 T 09-03-2017 IPR029060 PIN domain-like UA74_RS02805 75c03193d9b4e738ffe02643a0444e85 141 PRINTS PR01483 Fatty acid synthase signature 24 46 6.8E-6 T 09-03-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 UA74_RS02805 75c03193d9b4e738ffe02643a0444e85 141 PRINTS PR01483 Fatty acid synthase signature 46 67 6.8E-6 T 09-03-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 UA74_RS02805 75c03193d9b4e738ffe02643a0444e85 141 Gene3D G3DSA:3.10.129.10 8 140 2.1E-37 T 09-03-2017 IPR029069 HotDog domain UA74_RS02805 75c03193d9b4e738ffe02643a0444e85 141 SUPERFAMILY SSF54637 7 131 4.66E-28 T 09-03-2017 IPR029069 HotDog domain UA74_RS02805 75c03193d9b4e738ffe02643a0444e85 141 Pfam PF01575 MaoC like domain 16 121 2.3E-25 T 09-03-2017 IPR002539 MaoC-like domain UA74_RS02285 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Pfam PF00174 Oxidoreductase molybdopterin binding domain 232 384 1.1E-38 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 UA74_RS02285 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Gene3D G3DSA:2.60.40.650 400 502 2.5E-24 T 09-03-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 UA74_RS02285 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Gene3D G3DSA:3.90.420.10 214 399 6.8E-54 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 UA74_RS02285 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 SUPERFAMILY SSF81296 395 503 2.87E-25 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS02285 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 396 491 5.8E-7 T 09-03-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 UA74_RS02285 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 SUPERFAMILY SSF56524 214 401 8.5E-58 T 09-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 SMART SM00382 158 295 1.5E-19 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 Gene3D G3DSA:1.25.40.10 2 48 8.6E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 Pfam PF14559 Tetratricopeptide repeat 2 58 2.8E-7 T 09-03-2017 UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 SUPERFAMILY SSF52540 122 372 2.46E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 ProSitePatterns PS00674 AAA-protein family signature. 263 281 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 Gene3D G3DSA:1.10.8.60 303 377 1.3E-13 T 09-03-2017 UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 162 291 2.2E-43 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS22555 cba2ce02817825a9566ee29b0437b2c0 405 Gene3D G3DSA:3.40.50.300 120 302 4.0E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17420 e75df2cfae3518d7ce1407d995a8f884 293 Gene3D G3DSA:1.10.260.40 2 82 1.2E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17420 e75df2cfae3518d7ce1407d995a8f884 293 SUPERFAMILY SSF47413 32 81 1.92E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17420 e75df2cfae3518d7ce1407d995a8f884 293 Pfam PF13560 Helix-turn-helix domain 10 86 1.1E-14 T 09-03-2017 UA74_RS17420 e75df2cfae3518d7ce1407d995a8f884 293 SMART SM00530 6 83 1.9E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS09740 b49e3365665bea81cdc7d9963adef5d5 338 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 331 3.9E-82 T 09-03-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related UA74_RS09740 b49e3365665bea81cdc7d9963adef5d5 338 Pfam PF00296 Luciferase-like monooxygenase 9 304 1.8E-62 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS09740 b49e3365665bea81cdc7d9963adef5d5 338 SUPERFAMILY SSF51679 1 330 4.45E-75 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS09740 b49e3365665bea81cdc7d9963adef5d5 338 Gene3D G3DSA:3.20.20.30 2 330 7.9E-86 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS09740 b49e3365665bea81cdc7d9963adef5d5 338 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 2 330 6.3E-140 T 09-03-2017 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase UA74_RS28045 4425a390cbd06ed1688b713ccdc14122 155 Gene3D G3DSA:3.10.180.10 9 150 2.0E-39 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS28045 4425a390cbd06ed1688b713ccdc14122 155 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 144 3.1E-5 T 09-03-2017 IPR028973 PhnB-like UA74_RS28045 4425a390cbd06ed1688b713ccdc14122 155 SUPERFAMILY SSF54593 4 146 3.32E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS24970 4d3f5ec25af10f48da5a8cf77bd3231b 311 ProSitePatterns PS01125 ROK family signature. 124 151 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS24970 4d3f5ec25af10f48da5a8cf77bd3231b 311 Gene3D G3DSA:3.30.420.40 2 130 6.5E-38 T 09-03-2017 UA74_RS24970 4d3f5ec25af10f48da5a8cf77bd3231b 311 Pfam PF00480 ROK family 2 305 4.5E-72 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS24970 4d3f5ec25af10f48da5a8cf77bd3231b 311 Gene3D G3DSA:3.30.420.40 131 274 2.2E-49 T 09-03-2017 UA74_RS24970 4d3f5ec25af10f48da5a8cf77bd3231b 311 SUPERFAMILY SSF53067 2 308 3.0E-63 T 09-03-2017 UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 Gene3D G3DSA:1.10.10.10 107 160 1.2E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 SUPERFAMILY SSF54427 171 291 1.5E-10 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 SUPERFAMILY SSF88946 6 90 4.32E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 Gene3D G3DSA:3.10.450.50 170 291 1.4E-9 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 Gene3D G3DSA:1.10.1740.10 3 74 9.3E-15 T 09-03-2017 UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 Pfam PF08281 Sigma-70, region 4 108 159 1.2E-14 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 160 3.3E-16 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 Pfam PF04542 Sigma-70 region 2 9 72 3.0E-16 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS03540 67c934b934fb900f4724f05f20c2a4f7 311 SUPERFAMILY SSF88659 105 160 6.54E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 Pfam PF04542 Sigma-70 region 2 41 110 9.8E-19 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 SUPERFAMILY SSF88659 179 258 3.74E-17 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 SUPERFAMILY SSF88659 114 187 2.31E-16 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 SUPERFAMILY SSF88946 11 110 5.89E-29 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 Pfam PF04545 Sigma-70, region 4 206 255 2.8E-17 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 Pfam PF04539 Sigma-70 region 3 124 194 1.2E-12 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 36 257 1.8E-89 T 09-03-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 Gene3D G3DSA:1.10.601.10 27 109 2.3E-22 T 09-03-2017 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 Gene3D G3DSA:1.10.10.10 110 162 2.0E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11825 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.1E-10 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.1E-10 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.1E-10 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 65 78 1.1E-10 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11825 db8e473a578099ab6664c181738faba1 260 Gene3D G3DSA:1.10.10.10 198 259 5.7E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11825 db8e473a578099ab6664c181738faba1 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 257 8.3E-36 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 119 132 3.7E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 233 249 3.7E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 266 288 3.7E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 61 76 3.7E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 SUPERFAMILY SSF53474 9 286 6.38E-59 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 Pfam PF00561 alpha/beta hydrolase fold 35 276 3.4E-29 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 2.2E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 235 249 2.2E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 2.2E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15350 a7212357da86b52ba283095cb60eebea 296 Gene3D G3DSA:3.40.50.1820 8 286 2.8E-61 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS09115 6c44af178de164e378be0f218b38fad2 380 Gene3D G3DSA:3.20.20.70 52 157 3.5E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS09115 6c44af178de164e378be0f218b38fad2 380 Pfam PF04551 GcpE protein 21 361 6.3E-135 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_RS09115 6c44af178de164e378be0f218b38fad2 380 PIRSF PIRSF004640 12 372 1.2E-145 T 09-03-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_RS09115 6c44af178de164e378be0f218b38fad2 380 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.422 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_RS09115 6c44af178de164e378be0f218b38fad2 380 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 6.8E-128 T 09-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_RS09115 6c44af178de164e378be0f218b38fad2 380 SUPERFAMILY SSF56014 276 364 2.55E-12 T 09-03-2017 UA74_RS09115 6c44af178de164e378be0f218b38fad2 380 SUPERFAMILY SSF51717 28 219 1.65E-9 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS06380 524f6bf2df61d95b74b3d4707b28973f 398 Gene3D G3DSA:1.25.40.10 151 361 6.0E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06380 524f6bf2df61d95b74b3d4707b28973f 398 SUPERFAMILY SSF47413 1 55 1.1E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06380 524f6bf2df61d95b74b3d4707b28973f 398 SMART SM00530 7 62 1.7E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS06380 524f6bf2df61d95b74b3d4707b28973f 398 Gene3D G3DSA:1.10.260.40 2 55 1.1E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06380 524f6bf2df61d95b74b3d4707b28973f 398 Pfam PF13560 Helix-turn-helix domain 3 60 1.8E-13 T 09-03-2017 UA74_RS20200 c27e83d2fc5f5e079550ca6a1af3772f 487 Pfam PF03929 PepSY-associated TM region 2 367 4.9E-54 T 09-03-2017 IPR005625 PepSY-associated TM protein UA74_RS11575 d0618ab8b663b608c80e363598d0ffa6 297 SUPERFAMILY SSF53850 90 296 1.28E-42 T 09-03-2017 UA74_RS11575 d0618ab8b663b608c80e363598d0ffa6 297 Pfam PF03466 LysR substrate binding domain 88 295 1.4E-46 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS11575 d0618ab8b663b608c80e363598d0ffa6 297 Gene3D G3DSA:3.40.190.10 89 181 3.2E-23 T 09-03-2017 UA74_RS11575 d0618ab8b663b608c80e363598d0ffa6 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.1E-19 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS11575 d0618ab8b663b608c80e363598d0ffa6 297 Gene3D G3DSA:1.10.10.10 1 87 1.1E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11575 d0618ab8b663b608c80e363598d0ffa6 297 Gene3D G3DSA:3.40.190.10 182 268 7.4E-24 T 09-03-2017 UA74_RS11575 d0618ab8b663b608c80e363598d0ffa6 297 SUPERFAMILY SSF46785 1 112 9.77E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13460 0839565a14724157d08fffc94656279e 381 Gene3D G3DSA:3.30.390.10 2 114 2.8E-46 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS13460 0839565a14724157d08fffc94656279e 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_RS13460 0839565a14724157d08fffc94656279e 381 SMART SM00922 125 230 1.2E-15 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS13460 0839565a14724157d08fffc94656279e 381 SUPERFAMILY SSF54826 1 112 1.21E-31 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS13460 0839565a14724157d08fffc94656279e 381 Gene3D G3DSA:3.20.20.120 115 352 7.0E-73 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS13460 0839565a14724157d08fffc94656279e 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_RS13460 0839565a14724157d08fffc94656279e 381 Pfam PF13378 Enolase C-terminal domain-like 129 354 9.4E-56 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS13460 0839565a14724157d08fffc94656279e 381 SUPERFAMILY SSF51604 95 358 5.53E-70 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS13460 0839565a14724157d08fffc94656279e 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 2.7E-24 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS06510 3637b16cba38664dcb36db79f624fd34 280 Pfam PF00106 short chain dehydrogenase 7 145 4.0E-17 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06510 3637b16cba38664dcb36db79f624fd34 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 9.1E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06510 3637b16cba38664dcb36db79f624fd34 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.1E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06510 3637b16cba38664dcb36db79f624fd34 280 Gene3D G3DSA:3.40.50.720 6 226 3.9E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06510 3637b16cba38664dcb36db79f624fd34 280 SUPERFAMILY SSF51735 7 220 2.27E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 Pfam PF00376 MerR family regulatory protein 9 45 1.4E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 9.2E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 9.2E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 9.2E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 SMART SM00422 8 76 2.5E-24 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 Gene3D G3DSA:1.10.1660.10 7 61 7.6E-22 T 09-03-2017 UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 Gene3D G3DSA:1.10.1660.10 62 138 4.7E-18 T 09-03-2017 UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 Pfam PF09278 MerR, DNA binding 50 115 1.6E-18 T 09-03-2017 IPR015358 Transcription regulator MerR, DNA binding UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 SUPERFAMILY SSF46955 8 129 6.96E-30 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS10015 1c18b12f297915310721218e2723a0b8 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 145 7.9E-60 T 09-03-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 Gene3D G3DSA:1.10.150.240 25 63 4.9E-7 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 184 1.7E-22 T 09-03-2017 IPR023214 HAD-like domain UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 Gene3D G3DSA:3.40.50.1000 69 211 5.4E-41 T 09-03-2017 IPR023214 HAD-like domain UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 SUPERFAMILY SSF56784 9 207 6.35E-43 T 09-03-2017 IPR023214 HAD-like domain UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 4.8E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.8E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 4.8E-6 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS16060 0a742596da28937b41933c7e30796b3e 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 89 184 1.2E-16 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 SUPERFAMILY SSF53067 168 354 2.25E-33 T 09-03-2017 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 SUPERFAMILY SSF53067 2 152 7.45E-20 T 09-03-2017 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 Gene3D G3DSA:3.30.420.40 177 333 1.4E-20 T 09-03-2017 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 495 634 3.6E-21 T 09-03-2017 IPR023840 Type VII secretion system Rv3446c UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 PRINTS PR00301 70kDa heat shock protein signature 338 358 2.1E-9 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.1E-9 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.1E-9 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 PRINTS PR00301 70kDa heat shock protein signature 176 186 2.1E-9 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 PRINTS PR00301 70kDa heat shock protein signature 308 324 2.1E-9 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 311 325 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 170 183 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 Pfam PF00012 Hsp70 protein 96 357 3.7E-26 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS28235 20fee7c3a7d5fa675bc8d55d9bb1b60c 636 Gene3D G3DSA:3.30.420.40 4 176 2.3E-20 T 09-03-2017 UA74_RS01530 22833ddde7b22c6559cddc5ff467adca 127 TIGRFAM TIGR00526 folB_dom: FolB domain 3 120 1.5E-33 T 09-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS01530 22833ddde7b22c6559cddc5ff467adca 127 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 6.6E-38 T 09-03-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS01530 22833ddde7b22c6559cddc5ff467adca 127 SUPERFAMILY SSF55620 3 119 7.78E-36 T 09-03-2017 UA74_RS01530 22833ddde7b22c6559cddc5ff467adca 127 SMART SM00905 5 117 1.3E-46 T 09-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS01530 22833ddde7b22c6559cddc5ff467adca 127 Gene3D G3DSA:3.30.1130.10 1 119 6.1E-44 T 09-03-2017 UA74_RS01530 22833ddde7b22c6559cddc5ff467adca 127 Pfam PF02152 Dihydroneopterin aldolase 5 115 8.4E-34 T 09-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 Gene3D G3DSA:3.90.660.20 251 425 2.4E-25 T 09-03-2017 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 SUPERFAMILY SSF51905 8 325 5.44E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 SUPERFAMILY SSF51905 442 474 5.44E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 Pfam PF01593 Flavin containing amine oxidoreductase 17 473 2.0E-40 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 Gene3D G3DSA:1.10.3110.10 123 205 1.2E-17 T 09-03-2017 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 Gene3D G3DSA:3.50.50.60 11 62 5.7E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 Gene3D G3DSA:3.50.50.60 224 250 5.7E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 SUPERFAMILY SSF54373 310 425 1.31E-20 T 09-03-2017 UA74_RS23805 8e6488800a301197c9fc1bc2c96a99aa 489 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 9 473 9.2E-50 T 09-03-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_RS03105 dfe97ab493252701aad9b764be3a0776 178 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 1.2E-22 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 PIRSF PIRSF015589 43 749 7.5E-266 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF143724 167 376 3.73E-66 T 09-03-2017 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Hamap MF_00347 Polyphosphate kinase [ppk]. 60 745 34.86 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Pfam PF02503 Polyphosphate kinase middle domain 179 386 1.2E-69 T 09-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 62 741 4.0E-244 T 09-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Pfam PF13089 Polyphosphate kinase N-terminal domain 63 166 8.6E-35 T 09-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF140356 60 163 3.66E-35 T 09-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Pfam PF13090 Polyphosphate kinase C-terminal domain 397 741 5.6E-145 T 09-03-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Gene3D G3DSA:3.30.870.10 568 745 3.4E-61 T 09-03-2017 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Gene3D G3DSA:3.30.870.10 379 567 3.5E-79 T 09-03-2017 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF56024 569 743 2.24E-58 T 09-03-2017 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF56024 392 565 1.26E-56 T 09-03-2017 UA74_RS26020 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Gene3D G3DSA:3.30.1840.10 168 365 2.0E-73 T 09-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 Pfam PF07690 Major Facilitator Superfamily 34 426 9.8E-52 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 417 436 4.0E-5 T 09-03-2017 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 144 4.0E-5 T 09-03-2017 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 179 203 4.0E-5 T 09-03-2017 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 SUPERFAMILY SSF103473 264 436 1.31E-68 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 SUPERFAMILY SSF103473 24 213 1.31E-68 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 SUPERFAMILY SSF103473 488 515 1.31E-68 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 Gene3D G3DSA:1.20.1250.20 280 437 1.5E-24 T 09-03-2017 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 Gene3D G3DSA:1.20.1250.20 489 515 1.5E-24 T 09-03-2017 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 506 2.1E-70 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS16815 7301a47fcd23b6710b901c93e2c6d96e 532 Gene3D G3DSA:1.20.1250.20 27 209 7.1E-32 T 09-03-2017 UA74_RS13980 5304e025463e4112da97209d6eb8d146 292 Gene3D G3DSA:1.10.3720.10 84 273 2.9E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS13980 5304e025463e4112da97209d6eb8d146 292 SUPERFAMILY SSF161098 83 266 5.89E-34 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS13980 5304e025463e4112da97209d6eb8d146 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 269 4.2E-30 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS12485 e026233bb402d6d125112db86c856103 256 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 13 240 6.8E-75 T 09-03-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 UA74_RS12485 e026233bb402d6d125112db86c856103 256 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 247 6.5E-70 T 09-03-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 UA74_RS12485 e026233bb402d6d125112db86c856103 256 Gene3D G3DSA:3.40.50.1360 5 248 1.1E-73 T 09-03-2017 UA74_RS12485 e026233bb402d6d125112db86c856103 256 SUPERFAMILY SSF100950 6 249 3.24E-65 T 09-03-2017 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 Gene3D G3DSA:3.10.50.30 80 160 1.8E-14 T 09-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 158 1.6E-13 T 09-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 Pfam PF03449 Transcription elongation factor, N-terminal 10 78 2.5E-25 T 09-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 52 - T 09-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 160 27.95 T 09-03-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 SUPERFAMILY SSF46557 9 80 3.14E-23 T 09-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 SUPERFAMILY SSF54534 85 159 1.83E-11 T 09-03-2017 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 Gene3D G3DSA:1.10.287.180 7 78 4.1E-27 T 09-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 124 140 - T 09-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 UA74_RS04015 4f1c0d6ae2ac269babf49408f944f211 164 PIRSF PIRSF006092 3 162 2.2E-31 T 09-03-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:3.30.300.50 43 123 5.7E-27 T 09-03-2017 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 PIRSF PIRSF001134 1 383 2.3E-122 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 346 360 2.3E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 322 345 2.3E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 303 320 2.3E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 282 302 2.3E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 222 236 2.3E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:2.40.10.10 200 279 2.4E-26 T 09-03-2017 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:3.30.300.50 125 192 1.5E-17 T 09-03-2017 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:2.40.10.10 280 368 3.6E-29 T 09-03-2017 UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 SUPERFAMILY SSF50494 201 377 7.08E-34 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS01945 b4fdb69c81ea38b58c515c998a6518ab 383 Pfam PF02983 Alpha-lytic protease prodomain 125 180 2.8E-12 T 09-03-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_RS05370 a599cd5c9814655e0b7e7e24511b12f7 306 SUPERFAMILY SSF88946 7 95 6.67E-19 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS05370 a599cd5c9814655e0b7e7e24511b12f7 306 Pfam PF04542 Sigma-70 region 2 26 90 3.8E-11 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS05370 a599cd5c9814655e0b7e7e24511b12f7 306 Pfam PF08281 Sigma-70, region 4 117 168 5.5E-6 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS05370 a599cd5c9814655e0b7e7e24511b12f7 306 Gene3D G3DSA:1.10.1740.10 7 95 1.3E-20 T 09-03-2017 UA74_RS05370 a599cd5c9814655e0b7e7e24511b12f7 306 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 174 4.6E-17 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS05370 a599cd5c9814655e0b7e7e24511b12f7 306 SUPERFAMILY SSF88659 105 174 5.23E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS05370 a599cd5c9814655e0b7e7e24511b12f7 306 Gene3D G3DSA:1.10.10.10 110 174 8.7E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Gene3D G3DSA:2.30.38.10 453 532 1.8E-8 T 09-03-2017 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 39 661 5.4E-291 T 09-03-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 42 95 6.3E-23 T 09-03-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Gene3D G3DSA:3.40.50.980 279 437 4.6E-25 T 09-03-2017 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 ProSitePatterns PS00455 Putative AMP-binding domain signature. 273 284 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 SUPERFAMILY SSF56801 29 659 6.02E-173 T 09-03-2017 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Pfam PF13193 AMP-binding enzyme C-terminal domain 548 630 1.3E-26 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 23 664 50.558 T 09-03-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Pfam PF00501 AMP-binding enzyme 101 539 1.5E-89 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Gene3D G3DSA:3.30.300.30 534 647 2.7E-28 T 09-03-2017 UA74_RS01290 0114aecde93f7fd096842eafe7cde25f 671 Gene3D G3DSA:3.40.50.980 93 278 4.2E-41 T 09-03-2017 UA74_RS16930 a6b9b08ac4fbe577e0124381531ba575 305 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS16930 a6b9b08ac4fbe577e0124381531ba575 305 Gene3D G3DSA:3.40.50.300 2 223 6.3E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16930 a6b9b08ac4fbe577e0124381531ba575 305 Pfam PF00005 ABC transporter 17 157 1.5E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16930 a6b9b08ac4fbe577e0124381531ba575 305 SUPERFAMILY SSF52540 2 217 1.6E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16930 a6b9b08ac4fbe577e0124381531ba575 305 SMART SM00382 26 205 2.1E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 313 319 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 Gene3D G3DSA:3.40.50.150 223 424 2.8E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 Pfam PF02384 N-6 DNA Methylase 206 500 2.1E-63 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 SUPERFAMILY SSF116734 550 733 1.64E-28 T 09-03-2017 UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 SUPERFAMILY SSF53335 178 521 7.13E-74 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 SUPERFAMILY SSF53335 107 142 7.13E-74 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 Pfam PF01420 Type I restriction modification DNA specificity domain 597 719 2.3E-11 T 09-03-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 245 259 5.7E-20 T 09-03-2017 UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 310 322 5.7E-20 T 09-03-2017 UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 341 365 5.7E-20 T 09-03-2017 UA74_RS16005 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 237 5.7E-20 T 09-03-2017 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 6.8E-42 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 6.8E-42 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 6.8E-42 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 6.8E-42 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 6.8E-42 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 SUPERFAMILY SSF54919 3 135 2.23E-53 T 09-03-2017 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 Pfam PF00334 Nucleoside diphosphate kinase 3 134 2.5E-52 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 34.032 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 SMART SM00562 2 136 1.4E-71 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 09-03-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08235 fc94a161b7bfc6dc5d474920a0c046b1 136 Gene3D G3DSA:3.30.70.141 3 135 8.4E-55 T 09-03-2017 UA74_RS07210 e13b17ea78b1f0747077d8efce1d17ef 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 40.616 T 09-03-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS07210 e13b17ea78b1f0747077d8efce1d17ef 422 Gene3D G3DSA:3.65.10.10 221 416 3.0E-50 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_RS07210 e13b17ea78b1f0747077d8efce1d17ef 422 SUPERFAMILY SSF55205 4 417 1.7E-126 T 09-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 UA74_RS07210 e13b17ea78b1f0747077d8efce1d17ef 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 8.8E-163 T 09-03-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS07210 e13b17ea78b1f0747077d8efce1d17ef 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 1.5E-99 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_RS07210 e13b17ea78b1f0747077d8efce1d17ef 422 Gene3D G3DSA:3.65.10.10 22 220 1.1E-63 T 09-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_RS06805 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 Pfam PF00892 EamA-like transporter family 141 282 2.4E-14 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS06805 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 Pfam PF00892 EamA-like transporter family 8 130 6.7E-13 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS06805 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 SUPERFAMILY SSF103481 41 134 3.53E-12 T 09-03-2017 UA74_RS06805 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 SUPERFAMILY SSF103481 187 282 4.18E-9 T 09-03-2017 UA74_RS15680 aa189177b6334a942afe7187107b6af8 371 Gene3D G3DSA:3.20.20.70 2 362 7.0E-130 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS15680 aa189177b6334a942afe7187107b6af8 371 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 350 4.5E-72 T 09-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 UA74_RS15680 aa189177b6334a942afe7187107b6af8 371 SUPERFAMILY SSF51395 2 364 6.48E-114 T 09-03-2017 UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 Pfam PF00312 Ribosomal protein S15 8 88 4.4E-37 T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 SMART SM01387 8 88 1.7E-50 T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 Gene3D G3DSA:1.10.287.10 3 89 2.0E-38 T 09-03-2017 IPR009068 S15/NS1, RNA-binding UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.462 T 09-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.0E-38 T 09-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 8.0E-21 T 09-03-2017 UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 SUPERFAMILY SSF47060 3 89 5.89E-35 T 09-03-2017 IPR009068 S15/NS1, RNA-binding UA74_RS09475 90bac8355431a6f17569e2cbf61e6fc8 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 09-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS20415 657bdba513567f1e50a9b83206985921 30 Pfam PF04978 Protein of unknown function (DUF664) 2 29 1.7E-10 T 09-03-2017 IPR007061 Protein of unknown function DUF664 UA74_RS20415 657bdba513567f1e50a9b83206985921 30 Gene3D G3DSA:1.20.120.450 2 29 1.1E-7 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS20415 657bdba513567f1e50a9b83206985921 30 SUPERFAMILY SSF109854 2 28 7.87E-6 T 09-03-2017 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 655 91.558 T 09-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 SMART SM00433 37 648 0.0 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 655 5.1E-290 T 09-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF01751 Toprim domain 434 544 4.4E-16 T 09-03-2017 IPR006171 Toprim domain UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 175 1.5E-22 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Gene3D G3DSA:3.30.230.10 235 406 8.8E-75 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Gene3D G3DSA:3.40.50.670 419 637 2.7E-88 T 09-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 587 643 1.3E-26 T 09-03-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 437 445 - T 09-03-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 539 551 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 501 517 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 283 296 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 519 536 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 587 603 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 72 85 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 435 449 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 37 52 3.3E-70 T 09-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 SMART SM00387 33 176 2.0E-23 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 235 257 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 375 389 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 196 209 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 389 409 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 8 18 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 485 494 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 181 196 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 327 343 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 624 640 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 608 620 3.8E-69 T 09-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 SUPERFAMILY SSF54211 236 406 1.02E-58 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF00204 DNA gyrase B 236 405 3.9E-62 T 09-03-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 SUPERFAMILY SSF55874 7 210 4.24E-68 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 Gene3D G3DSA:3.30.565.10 8 212 8.3E-84 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00030 49bf493e1f719816b255838d5d762d68 655 SUPERFAMILY SSF56719 409 650 7.06E-83 T 09-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UA74_RS00990 cdd104c23335f05aa234fd31e3fad620 264 Gene3D G3DSA:2.115.10.20 46 227 2.8E-19 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS00990 cdd104c23335f05aa234fd31e3fad620 264 Pfam PF04616 Glycosyl hydrolases family 43 45 176 1.1E-9 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_RS00990 cdd104c23335f05aa234fd31e3fad620 264 SUPERFAMILY SSF75005 45 228 1.16E-22 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS01485 17dde9aa7624c1c0ff34c6d629514dc3 353 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 14 352 5.9E-99 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 UA74_RS01485 17dde9aa7624c1c0ff34c6d629514dc3 353 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 14 352 7.3E-119 T 09-03-2017 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated UA74_RS01485 17dde9aa7624c1c0ff34c6d629514dc3 353 Pfam PF10103 Zinicin-like metallopeptidase 14 348 3.1E-103 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 UA74_RS01485 17dde9aa7624c1c0ff34c6d629514dc3 353 SUPERFAMILY SSF55486 13 351 3.66E-93 T 09-03-2017 UA74_RS27410 5c7e5984dfdb55f624bdccae71378bbe 529 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 8 525 3.6E-229 T 09-03-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS27410 5c7e5984dfdb55f624bdccae71378bbe 529 Pfam PF01642 Methylmalonyl-CoA mutase 8 521 5.7E-218 T 09-03-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS27410 5c7e5984dfdb55f624bdccae71378bbe 529 SUPERFAMILY SSF51703 8 523 2.88E-201 T 09-03-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS27410 5c7e5984dfdb55f624bdccae71378bbe 529 Gene3D G3DSA:3.20.20.240 8 523 6.5E-221 T 09-03-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS03350 3fc2968e2d7bb63b493a5ef66ed7c966 127 Gene3D G3DSA:3.30.1330.40 3 127 2.1E-32 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS03350 3fc2968e2d7bb63b493a5ef66ed7c966 127 SUPERFAMILY SSF55298 9 127 5.97E-28 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS03350 3fc2968e2d7bb63b493a5ef66ed7c966 127 Pfam PF01042 Endoribonuclease L-PSP 15 125 4.6E-18 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family UA74_RS29850 a268e93591478a5466fd50e0b336da86 618 Gene3D G3DSA:2.120.10.30 176 475 5.0E-39 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS29850 a268e93591478a5466fd50e0b336da86 618 Pfam PF00578 AhpC/TSA family 12 132 1.4E-8 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS29850 a268e93591478a5466fd50e0b336da86 618 SUPERFAMILY SSF52833 13 176 4.55E-30 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS29850 a268e93591478a5466fd50e0b336da86 618 SUPERFAMILY SSF101898 167 475 1.33E-28 T 09-03-2017 UA74_RS29850 a268e93591478a5466fd50e0b336da86 618 Gene3D G3DSA:3.40.30.10 12 156 2.2E-38 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS04600 0f239cc156a330cc3d396345170f261c 409 Pfam PF07690 Major Facilitator Superfamily 4 234 1.5E-24 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS04600 0f239cc156a330cc3d396345170f261c 409 Pfam PF07690 Major Facilitator Superfamily 235 387 1.3E-10 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS04600 0f239cc156a330cc3d396345170f261c 409 Gene3D G3DSA:1.20.1250.20 2 179 8.2E-25 T 09-03-2017 UA74_RS04600 0f239cc156a330cc3d396345170f261c 409 Gene3D G3DSA:1.20.1250.20 209 382 1.1E-12 T 09-03-2017 UA74_RS04600 0f239cc156a330cc3d396345170f261c 409 SUPERFAMILY SSF103473 2 382 3.53E-49 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16065 bc29db39bb4ce48e315b4313ebb8086c 402 Gene3D G3DSA:1.10.260.40 7 70 9.9E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16065 bc29db39bb4ce48e315b4313ebb8086c 402 Pfam PF13560 Helix-turn-helix domain 10 68 4.1E-12 T 09-03-2017 UA74_RS16065 bc29db39bb4ce48e315b4313ebb8086c 402 SMART SM00530 12 68 2.9E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS16065 bc29db39bb4ce48e315b4313ebb8086c 402 SUPERFAMILY SSF47413 2 70 2.82E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 Gene3D G3DSA:3.40.50.720 3 217 1.2E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 Pfam PF00106 short chain dehydrogenase 6 192 1.1E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 SUPERFAMILY SSF51735 3 216 1.12E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.3E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.3E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.3E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.7E-28 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.7E-28 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.7E-28 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.7E-28 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.7E-28 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11055 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 184 0.0031 T 09-03-2017 UA74_RS11260 2857bb757e0f31fdb222280e8425304a 178 Gene3D G3DSA:2.40.320.10 4 153 1.5E-25 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 UA74_RS11260 2857bb757e0f31fdb222280e8425304a 178 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 4 131 7.0E-6 T 09-03-2017 UA74_RS11260 2857bb757e0f31fdb222280e8425304a 178 SUPERFAMILY SSF55154 4 144 7.85E-20 T 09-03-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 UA74_RS11260 2857bb757e0f31fdb222280e8425304a 178 Pfam PF01928 CYTH domain 3 138 1.3E-9 T 09-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 UA74_RS13420 c2bf835538fc1a6854adc8195d89142a 188 Gene3D G3DSA:1.10.357.10 57 182 4.5E-19 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS13420 c2bf835538fc1a6854adc8195d89142a 188 SUPERFAMILY SSF46689 4 60 1.09E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13420 c2bf835538fc1a6854adc8195d89142a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 3.2E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13420 c2bf835538fc1a6854adc8195d89142a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.7E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13420 c2bf835538fc1a6854adc8195d89142a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.7E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13420 c2bf835538fc1a6854adc8195d89142a 188 Gene3D G3DSA:1.10.10.60 6 56 4.1E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS19020 5371c0845185af9d1c12ddba1390c773 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 2.2E-11 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS19020 5371c0845185af9d1c12ddba1390c773 132 SUPERFAMILY SSF54593 3 130 9.76E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS19020 5371c0845185af9d1c12ddba1390c773 132 Gene3D G3DSA:3.10.180.10 2 130 1.6E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS04270 30d043148b6c8efcd492f2e2e2cab64f 437 Pfam PF00463 Isocitrate lyase family 263 433 7.5E-43 T 09-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 UA74_RS04270 30d043148b6c8efcd492f2e2e2cab64f 437 Pfam PF00463 Isocitrate lyase family 24 262 1.7E-56 T 09-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 UA74_RS04270 30d043148b6c8efcd492f2e2e2cab64f 437 Gene3D G3DSA:3.20.20.60 17 419 2.9E-157 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS04270 30d043148b6c8efcd492f2e2e2cab64f 437 ProSitePatterns PS00161 Isocitrate lyase signature. 199 204 - T 09-03-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 UA74_RS04270 30d043148b6c8efcd492f2e2e2cab64f 437 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 18 261 7.7E-107 T 09-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 UA74_RS04270 30d043148b6c8efcd492f2e2e2cab64f 437 PIRSF PIRSF001362 10 437 2.2E-227 T 09-03-2017 UA74_RS04270 30d043148b6c8efcd492f2e2e2cab64f 437 SUPERFAMILY SSF51621 17 437 4.17E-150 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS09605 2fe5fe89a4bc497401e2db7e02283d76 204 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_RS09605 2fe5fe89a4bc497401e2db7e02283d76 204 PIRSF PIRSF000847 17 199 2.9E-45 T 09-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 UA74_RS09605 2fe5fe89a4bc497401e2db7e02283d76 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 20 90 2.8E-14 T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_RS09605 2fe5fe89a4bc497401e2db7e02283d76 204 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 20 189 1.0E-41 T 09-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 UA74_RS02910 349c50f67e96e5c3b7c62f0ce5d77bec 156 PIRSF PIRSF002122 5 156 7.0E-56 T 09-03-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 UA74_RS02910 349c50f67e96e5c3b7c62f0ce5d77bec 156 SUPERFAMILY SSF47973 1 149 5.1E-57 T 09-03-2017 IPR023798 Ribosomal protein S7 domain UA74_RS02910 349c50f67e96e5c3b7c62f0ce5d77bec 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.9E-60 T 09-03-2017 IPR023798 Ribosomal protein S7 domain UA74_RS02910 349c50f67e96e5c3b7c62f0ce5d77bec 156 Gene3D G3DSA:1.10.455.10 8 156 1.6E-61 T 09-03-2017 IPR023798 Ribosomal protein S7 domain UA74_RS02910 349c50f67e96e5c3b7c62f0ce5d77bec 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.2E-65 T 09-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 UA74_RS02910 349c50f67e96e5c3b7c62f0ce5d77bec 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 09-03-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02910 349c50f67e96e5c3b7c62f0ce5d77bec 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.948 T 09-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 UA74_RS08255 6113e589605fade79c80ad0bef74162d 655 SMART SM00729 264 487 2.0E-30 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS08255 6113e589605fade79c80ad0bef74162d 655 Pfam PF04055 Radical SAM superfamily 268 432 4.4E-18 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS08255 6113e589605fade79c80ad0bef74162d 655 SUPERFAMILY SSF102114 226 634 5.36E-50 T 09-03-2017 UA74_RS08255 6113e589605fade79c80ad0bef74162d 655 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 13 620 3.9E-206 T 09-03-2017 IPR023862 Conserved hypothetical protein CHP03960, radical SAM UA74_RS08255 6113e589605fade79c80ad0bef74162d 655 Gene3D G3DSA:3.80.30.20 263 491 2.5E-45 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 SUPERFAMILY SSF49464 482 557 2.82E-11 T 09-03-2017 IPR008969 Carboxypeptidase-like, regulatory domain UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 405 415 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 Pfam PF00082 Subtilase family 173 445 2.1E-39 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 Gene3D G3DSA:3.40.50.200 153 471 2.6E-71 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 Pfam PF13620 Carboxypeptidase regulatory-like domain 482 558 1.5E-11 T 09-03-2017 UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 Pfam PF13620 Carboxypeptidase regulatory-like domain 565 640 2.3E-12 T 09-03-2017 UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 Gene3D G3DSA:2.60.40.1120 565 642 3.2E-10 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 PRINTS PR00723 Subtilisin serine protease family (S8) signature 227 240 3.6E-18 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 PRINTS PR00723 Subtilisin serine protease family (S8) signature 404 420 3.6E-18 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 192 3.6E-18 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 Gene3D G3DSA:2.60.40.1120 482 558 1.3E-14 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 SUPERFAMILY SSF52743 153 472 4.58E-62 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS11280 89131912527012133ccb5347b90ea6e7 856 SUPERFAMILY SSF49452 559 635 5.89E-11 T 09-03-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_RS22530 7610d5efc4d0e030c952c16f900ec4ad 256 SUPERFAMILY SSF81923 60 196 2.35E-23 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS22530 7610d5efc4d0e030c952c16f900ec4ad 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 74 122 1.6E-6 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS22530 7610d5efc4d0e030c952c16f900ec4ad 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 151 200 1.9E-14 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS22530 7610d5efc4d0e030c952c16f900ec4ad 256 Gene3D G3DSA:1.10.1780.10 59 199 1.7E-32 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS20395 e38f3bd013728d7a0581ae2401f461c0 349 SUPERFAMILY SSF81345 12 342 1.96E-65 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS20395 e38f3bd013728d7a0581ae2401f461c0 349 Pfam PF01032 FecCD transport family 28 342 5.9E-76 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS20395 e38f3bd013728d7a0581ae2401f461c0 349 Gene3D G3DSA:1.10.3470.10 17 347 7.1E-86 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS04410 9342c07cc1572b254a72418255ae56f8 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 329 4.2E-40 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04410 9342c07cc1572b254a72418255ae56f8 331 Gene3D G3DSA:1.10.3720.10 88 325 4.4E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04410 9342c07cc1572b254a72418255ae56f8 331 SUPERFAMILY SSF161098 93 162 2.13E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04410 9342c07cc1572b254a72418255ae56f8 331 SUPERFAMILY SSF161098 193 317 2.13E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21340 78924cbd4bb58614824aae59159ad1ee 731 Pfam PF00916 Sulfate permease family 1 347 6.9E-67 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UA74_RS21340 78924cbd4bb58614824aae59159ad1ee 731 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 599 619 - T 09-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS21340 78924cbd4bb58614824aae59159ad1ee 731 SUPERFAMILY SSF53056 486 717 1.57E-50 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS21340 78924cbd4bb58614824aae59159ad1ee 731 Gene3D G3DSA:3.40.1050.10 499 723 2.5E-64 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS21340 78924cbd4bb58614824aae59159ad1ee 731 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 555 562 - T 09-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS21340 78924cbd4bb58614824aae59159ad1ee 731 SMART SM00947 543 715 5.8E-53 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS21340 78924cbd4bb58614824aae59159ad1ee 731 Pfam PF00484 Carbonic anhydrase 551 710 6.6E-45 T 09-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_RS06965 edde150ce0c621e97bdad167f4aa0b5a 202 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 178 2.1E-59 T 09-03-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG UA74_RS06965 edde150ce0c621e97bdad167f4aa0b5a 202 SUPERFAMILY SSF102405 2 178 9.62E-63 T 09-03-2017 UA74_RS06965 edde150ce0c621e97bdad167f4aa0b5a 202 Pfam PF03641 Possible lysine decarboxylase 45 173 6.3E-44 T 09-03-2017 IPR031100 LOG family UA74_RS06965 edde150ce0c621e97bdad167f4aa0b5a 202 Gene3D G3DSA:3.40.50.450 2 181 8.0E-70 T 09-03-2017 UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 SUPERFAMILY SSF53448 342 359 1.01E-69 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 SUPERFAMILY SSF53448 7 280 1.01E-69 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 SUPERFAMILY SSF51161 298 398 2.77E-18 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 6.1E-139 T 09-03-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 09-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Gene3D G3DSA:3.90.550.10 9 287 3.7E-70 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Gene3D G3DSA:3.90.550.10 325 368 3.7E-70 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 09-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 09-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Pfam PF00483 Nucleotidyl transferase 9 276 2.0E-69 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_RS04610 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 47.426 T 09-03-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 UA74_RS23415 a3385de661c19a4a4a31542710feacde 462 SUPERFAMILY SSF56059 120 338 2.5E-29 T 09-03-2017 UA74_RS23415 a3385de661c19a4a4a31542710feacde 462 Pfam PF13535 ATP-grasp domain 136 295 1.9E-8 T 09-03-2017 UA74_RS23415 a3385de661c19a4a4a31542710feacde 462 Gene3D G3DSA:3.30.470.20 97 414 5.2E-23 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 Pfam PF00083 Sugar (and other) transporter 18 449 3.1E-91 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 321 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 25 35 2.1E-17 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 108 127 2.1E-17 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 373 385 2.1E-17 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 350 371 2.1E-17 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 260 270 2.1E-17 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 SUPERFAMILY SSF103473 5 445 4.84E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 Gene3D G3DSA:1.20.1250.20 251 443 1.8E-19 T 09-03-2017 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 Gene3D G3DSA:1.20.1250.20 19 196 3.5E-19 T 09-03-2017 UA74_RS19935 6bae871df8fd8ab9eccc467ec4a5289e 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 445 1.5E-85 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS22440 8deae861a4d7651987ea3f1034883d25 423 Gene3D G3DSA:3.30.1870.10 70 137 1.4E-8 T 09-03-2017 UA74_RS22440 8deae861a4d7651987ea3f1034883d25 423 Gene3D G3DSA:3.40.1660.10 5 68 6.3E-34 T 09-03-2017 UA74_RS22440 8deae861a4d7651987ea3f1034883d25 423 Gene3D G3DSA:3.40.1660.10 283 387 6.3E-34 T 09-03-2017 UA74_RS22440 8deae861a4d7651987ea3f1034883d25 423 Pfam PF05139 Erythromycin esterase 67 409 2.1E-37 T 09-03-2017 IPR007815 Erythromycin esterase GO:0046677 UA74_RS22440 8deae861a4d7651987ea3f1034883d25 423 SUPERFAMILY SSF159501 4 417 1.15E-63 T 09-03-2017 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 SUPERFAMILY SSF47413 12 70 1.17E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 Pfam PF13377 Periplasmic binding protein-like domain 178 339 3.9E-35 T 09-03-2017 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 SUPERFAMILY SSF53822 72 341 1.04E-64 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 Gene3D G3DSA:1.10.260.40 13 65 6.7E-23 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 Gene3D G3DSA:3.40.50.2300 183 321 1.1E-46 T 09-03-2017 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 Gene3D G3DSA:3.40.50.2300 66 182 3.0E-31 T 09-03-2017 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 09-03-2017 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 3.6E-18 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS17915 26fb8ac7ca84fd1c7de16f9641580376 344 SMART SM00354 12 82 3.8E-24 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS00530 252514659cba61f02e39f2561c4077f8 203 SUPERFAMILY SSF46785 2 71 4.61E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00530 252514659cba61f02e39f2561c4077f8 203 Pfam PF09339 IclR helix-turn-helix domain 2 54 6.2E-11 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS00530 252514659cba61f02e39f2561c4077f8 203 SUPERFAMILY SSF55781 58 202 2.09E-16 T 09-03-2017 IPR029016 GAF domain-like UA74_RS00530 252514659cba61f02e39f2561c4077f8 203 Gene3D G3DSA:1.10.10.10 2 68 2.1E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00530 252514659cba61f02e39f2561c4077f8 203 SMART SM00346 2 87 8.2E-10 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS00530 252514659cba61f02e39f2561c4077f8 203 Gene3D G3DSA:3.30.450.40 77 137 3.6E-10 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22575 b1d42848c08369dcb87da48118da0d6f 269 SUPERFAMILY SSF52540 3 249 1.1E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22575 b1d42848c08369dcb87da48118da0d6f 269 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS22575 b1d42848c08369dcb87da48118da0d6f 269 Pfam PF00005 ABC transporter 22 177 2.3E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS22575 b1d42848c08369dcb87da48118da0d6f 269 SMART SM00382 29 227 3.2E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22575 b1d42848c08369dcb87da48118da0d6f 269 Gene3D G3DSA:3.40.50.300 2 251 2.7E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 Pfam PF00723 Glycosyl hydrolases family 15 474 784 1.0E-35 T 09-03-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 Pfam PF02358 Trehalose-phosphatase 27 217 4.5E-32 T 09-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 SUPERFAMILY SSF48208 461 837 6.05E-92 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 Gene3D G3DSA:1.50.10.10 476 840 5.7E-80 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 SUPERFAMILY SSF56784 24 250 3.67E-35 T 09-03-2017 IPR023214 HAD-like domain UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 Gene3D G3DSA:3.40.50.1000 174 256 1.9E-39 T 09-03-2017 IPR023214 HAD-like domain UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 Gene3D G3DSA:3.40.50.1000 23 99 1.9E-39 T 09-03-2017 IPR023214 HAD-like domain UA74_RS01780 2aecff50162198bac96edd054e5f78f3 842 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 23 250 1.9E-34 T 09-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 SUPERFAMILY SSF50129 4 196 8.78E-57 T 09-03-2017 IPR011032 GroES-like UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 182 253 3.1E-7 T 09-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 76 90 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 SUPERFAMILY SSF51735 172 363 1.08E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 2 403 2.7E-229 T 09-03-2017 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Gene3D G3DSA:3.40.50.720 198 314 7.2E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Gene3D G3DSA:3.90.180.10 4 197 1.7E-43 T 09-03-2017 IPR011032 GroES-like UA74_RS18340 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 1.1E-25 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS16565 70415935a63c13db2addf9229e01f945 288 PIRSF PIRSF000105 1 288 9.9E-77 T 09-03-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 UA74_RS16565 70415935a63c13db2addf9229e01f945 288 SUPERFAMILY SSF48179 191 288 1.87E-31 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS16565 70415935a63c13db2addf9229e01f945 288 Gene3D G3DSA:3.40.50.720 4 192 1.5E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16565 70415935a63c13db2addf9229e01f945 288 Gene3D G3DSA:1.10.1040.10 193 288 7.4E-34 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS16565 70415935a63c13db2addf9229e01f945 288 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 186 2.9E-50 T 09-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 UA74_RS16565 70415935a63c13db2addf9229e01f945 288 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 287 2.6E-31 T 09-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 UA74_RS16565 70415935a63c13db2addf9229e01f945 288 SUPERFAMILY SSF51735 4 186 3.29E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 Gene3D G3DSA:1.10.10.60 8 63 1.5E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 63 105 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 SUPERFAMILY SSF46689 9 60 4.44E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 SUPERFAMILY SSF46689 62 115 1.08E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 SMART SM00342 26 109 4.3E-30 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 Pfam PF12833 Helix-turn-helix domain 32 111 2.5E-27 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 Gene3D G3DSA:1.10.10.60 64 111 3.6E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 78 93 3.1E-5 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_RS20480 2b9a7ceb3493fc4918bcad22e5576c04 140 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 93 109 3.1E-5 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_RS24005 e038051979bcf8131f2500665f19eb95 106 SUPERFAMILY SSF140453 4 99 6.15E-5 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS26670 622e32e1af71395c461a1cd2dd23f9a0 338 SUPERFAMILY SSF52540 117 328 7.99E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26670 622e32e1af71395c461a1cd2dd23f9a0 338 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 74 327 7.9E-41 T 09-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 UA74_RS26670 622e32e1af71395c461a1cd2dd23f9a0 338 Gene3D G3DSA:1.10.40.50 269 329 1.1E-10 T 09-03-2017 UA74_RS26670 622e32e1af71395c461a1cd2dd23f9a0 338 Pfam PF03193 Protein of unknown function, DUF258 99 267 4.3E-40 T 09-03-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 UA74_RS26670 622e32e1af71395c461a1cd2dd23f9a0 338 Gene3D G3DSA:3.40.50.300 117 267 1.1E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24080 a8fbfe1dfa504b92004bc1921f72d104 274 Gene3D G3DSA:1.10.3720.10 75 270 9.7E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24080 a8fbfe1dfa504b92004bc1921f72d104 274 SUPERFAMILY SSF161098 77 258 5.89E-27 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24080 a8fbfe1dfa504b92004bc1921f72d104 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 261 1.0E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04035 a73611e4ad376d228d6fa1175e3a7f81 485 Gene3D G3DSA:3.40.50.150 274 443 2.9E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04035 a73611e4ad376d228d6fa1175e3a7f81 485 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 243 2.8E-110 T 09-03-2017 IPR024740 Hen1, N-terminal UA74_RS04035 a73611e4ad376d228d6fa1175e3a7f81 485 Pfam PF13489 Methyltransferase domain 270 433 6.9E-10 T 09-03-2017 UA74_RS04035 a73611e4ad376d228d6fa1175e3a7f81 485 SUPERFAMILY SSF53335 271 439 2.64E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04035 a73611e4ad376d228d6fa1175e3a7f81 485 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 2 465 9.8E-197 T 09-03-2017 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial UA74_RS13970 ef088a75737e33f81c64455e4d82cdda 271 SUPERFAMILY SSF52540 20 234 2.73E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13970 ef088a75737e33f81c64455e4d82cdda 271 Pfam PF00005 ABC transporter 38 177 1.1E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13970 ef088a75737e33f81c64455e4d82cdda 271 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13970 ef088a75737e33f81c64455e4d82cdda 271 SMART SM00382 47 228 2.2E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13970 ef088a75737e33f81c64455e4d82cdda 271 Gene3D G3DSA:3.40.50.300 15 233 2.5E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22420 8d298436550b9c50360db22118515599 440 SUPERFAMILY SSF103473 14 417 3.27E-77 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22420 8d298436550b9c50360db22118515599 440 Gene3D G3DSA:1.20.1250.20 230 418 1.8E-22 T 09-03-2017 UA74_RS22420 8d298436550b9c50360db22118515599 440 PIRSF PIRSF002808 1 429 3.1E-34 T 09-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 UA74_RS22420 8d298436550b9c50360db22118515599 440 Pfam PF07690 Major Facilitator Superfamily 28 382 5.1E-57 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS22420 8d298436550b9c50360db22118515599 440 Gene3D G3DSA:1.20.1250.20 23 214 2.6E-44 T 09-03-2017 UA74_RS10535 1921d34775a821016003a5ec2ddff31d 229 SUPERFAMILY SSF53597 3 222 1.7E-46 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS10535 1921d34775a821016003a5ec2ddff31d 229 Gene3D G3DSA:3.40.430.10 3 223 6.9E-58 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS10535 1921d34775a821016003a5ec2ddff31d 229 Pfam PF01872 RibD C-terminal domain 5 214 2.8E-40 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS26080 9150701b64345dd78c49ccdbc82c96a5 257 Gene3D G3DSA:3.90.850.10 52 256 6.5E-88 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS26080 9150701b64345dd78c49ccdbc82c96a5 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 60 255 2.8E-67 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS26080 9150701b64345dd78c49ccdbc82c96a5 257 Pfam PF10370 Domain of unknown function (DUF2437) 2 55 1.2E-13 T 09-03-2017 IPR018833 Domain of unknown function DUF2437 UA74_RS26080 9150701b64345dd78c49ccdbc82c96a5 257 SUPERFAMILY SSF56529 52 255 1.44E-79 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS24075 c30483ed7f6d5e9b6ab0a63663749736 346 SUPERFAMILY SSF53850 45 275 2.23E-37 T 09-03-2017 UA74_RS24075 c30483ed7f6d5e9b6ab0a63663749736 346 Gene3D G3DSA:3.40.190.10 129 215 1.8E-17 T 09-03-2017 UA74_RS24075 c30483ed7f6d5e9b6ab0a63663749736 346 SMART SM00062 46 269 0.0098 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS24075 c30483ed7f6d5e9b6ab0a63663749736 346 Pfam PF09084 NMT1/THI5 like 55 263 1.1E-37 T 09-03-2017 IPR015168 SsuA/THI5-like UA74_RS17730 fdd697dee94b8289fb4be4b9105481c7 253 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 12 228 4.6E-53 T 09-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein UA74_RS17730 fdd697dee94b8289fb4be4b9105481c7 253 SUPERFAMILY SSF52540 12 228 1.05E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17730 fdd697dee94b8289fb4be4b9105481c7 253 Gene3D G3DSA:3.40.50.300 12 228 2.2E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21105 a4640b67202bfa77bc676adb988dd37c 261 SUPERFAMILY SSF56784 25 204 6.34E-36 T 09-03-2017 IPR023214 HAD-like domain UA74_RS21105 a4640b67202bfa77bc676adb988dd37c 261 Gene3D G3DSA:1.10.150.240 39 81 2.4E-13 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 UA74_RS21105 a4640b67202bfa77bc676adb988dd37c 261 Gene3D G3DSA:3.40.50.1000 82 201 1.1E-34 T 09-03-2017 IPR023214 HAD-like domain UA74_RS21105 a4640b67202bfa77bc676adb988dd37c 261 Pfam PF13419 Haloacid dehalogenase-like hydrolase 28 198 1.3E-15 T 09-03-2017 IPR023214 HAD-like domain UA74_RS21105 a4640b67202bfa77bc676adb988dd37c 261 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 105 198 4.6E-12 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS13505 01806b3c3ffd0d6e3443c09f93b1f896 71 Pfam PF04149 Domain of unknown function (DUF397) 6 63 5.3E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS13330 24932057ff4134c15b1fdf0f3211a098 329 Gene3D G3DSA:1.10.3470.10 2 325 6.4E-99 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS13330 24932057ff4134c15b1fdf0f3211a098 329 Pfam PF01032 FecCD transport family 8 323 1.7E-88 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS13330 24932057ff4134c15b1fdf0f3211a098 329 SUPERFAMILY SSF81345 2 324 1.03E-77 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS19950 445e41b059cd76fe50602883431c83c4 239 SUPERFAMILY SSF46689 8 81 2.05E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS19950 445e41b059cd76fe50602883431c83c4 239 Gene3D G3DSA:1.10.357.10 4 225 1.8E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS19950 445e41b059cd76fe50602883431c83c4 239 SUPERFAMILY SSF48498 90 225 3.56E-25 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS19950 445e41b059cd76fe50602883431c83c4 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 2.1E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04285 65b58a9fe051e38b2910c18dc22c4ae1 252 Gene3D G3DSA:3.40.50.300 9 211 2.2E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04285 65b58a9fe051e38b2910c18dc22c4ae1 252 Pfam PF00005 ABC transporter 12 158 2.3E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04285 65b58a9fe051e38b2910c18dc22c4ae1 252 SMART SM00382 21 207 4.3E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04285 65b58a9fe051e38b2910c18dc22c4ae1 252 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS04285 65b58a9fe051e38b2910c18dc22c4ae1 252 SUPERFAMILY SSF52540 2 210 5.06E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02260 fb5649d71806f0840c29ac5a6eb3b890 376 SMART SM00563 162 281 9.8E-15 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS02260 fb5649d71806f0840c29ac5a6eb3b890 376 Pfam PF01553 Acyltransferase 149 278 2.1E-15 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS02260 fb5649d71806f0840c29ac5a6eb3b890 376 SUPERFAMILY SSF69593 142 367 4.84E-32 T 09-03-2017 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 Gene3D G3DSA:3.40.50.300 4 170 1.9E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 Hamap MF_00109 Shikimate kinase [aroK]. 4 169 27.001 T 09-03-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 SUPERFAMILY SSF52540 7 168 1.78E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 31 44 1.8E-17 T 09-03-2017 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 59 67 1.8E-17 T 09-03-2017 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 7 22 1.8E-17 T 09-03-2017 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 97 114 1.8E-17 T 09-03-2017 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 77 86 1.8E-17 T 09-03-2017 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 09-03-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_RS12220 53717f27064d0ed50377091e676e93dd 188 Pfam PF01202 Shikimate kinase 13 168 7.4E-42 T 09-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_RS11015 f4f643f7e8b97c8d9fa27dba6bdba043 135 Pfam PF07876 Stress responsive A/B Barrel Domain 2 89 5.4E-8 T 09-03-2017 IPR013097 Stress responsive alpha-beta barrel UA74_RS11015 f4f643f7e8b97c8d9fa27dba6bdba043 135 SMART SM00886 2 90 1.5E-4 T 09-03-2017 IPR013097 Stress responsive alpha-beta barrel UA74_RS11015 f4f643f7e8b97c8d9fa27dba6bdba043 135 SUPERFAMILY SSF54909 1 95 1.25E-12 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS11015 f4f643f7e8b97c8d9fa27dba6bdba043 135 Gene3D G3DSA:3.30.70.900 1 92 3.8E-10 T 09-03-2017 UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 SUPERFAMILY SSF53335 224 258 1.59E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 SUPERFAMILY SSF53335 295 408 1.59E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 SUPERFAMILY SSF53335 15 178 1.59E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 Gene3D G3DSA:3.40.50.150 16 169 3.4E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 Pfam PF00145 C-5 cytosine-specific DNA methylase 17 180 5.3E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 78 90 - T 09-03-2017 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 15 31 7.3E-6 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 118 132 7.3E-6 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 162 175 7.3E-6 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 Gene3D G3DSA:3.90.120.10 291 397 2.6E-5 T 09-03-2017 UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 Gene3D G3DSA:3.90.120.10 170 188 2.6E-5 T 09-03-2017 UA74_RS16340 62d7caf4094d9c4aca3bd683edc33f7e 444 Gene3D G3DSA:3.90.120.10 225 247 2.6E-5 T 09-03-2017 UA74_RS10330 31117d1ce4cefca5db0692c6a3e0fab2 715 Pfam PF10592 AIPR protein 252 535 1.1E-38 T 09-03-2017 IPR018891 Abortive bacteriophage infection, resistance UA74_RS10330 31117d1ce4cefca5db0692c6a3e0fab2 715 Gene3D G3DSA:3.40.1350.10 71 127 8.7E-5 T 09-03-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 UA74_RS17550 e73e5c0b7237b98ad16fba92fce1a644 181 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 27 161 4.8E-28 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS17550 e73e5c0b7237b98ad16fba92fce1a644 181 SUPERFAMILY SSF55961 13 162 3.14E-43 T 09-03-2017 UA74_RS17550 e73e5c0b7237b98ad16fba92fce1a644 181 Gene3D G3DSA:3.30.530.20 12 162 3.5E-47 T 09-03-2017 IPR023393 START-like domain UA74_RS12505 504fcf841dbefece226f6856fd26c7f3 374 Pfam PF00923 Transaldolase 17 361 4.9E-77 T 09-03-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 UA74_RS12505 504fcf841dbefece226f6856fd26c7f3 374 Hamap MF_00493 Transaldolase [tal]. 1 372 152.684 T 09-03-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS12505 504fcf841dbefece226f6856fd26c7f3 374 SUPERFAMILY SSF51569 8 365 4.27E-74 T 09-03-2017 UA74_RS12505 504fcf841dbefece226f6856fd26c7f3 374 Gene3D G3DSA:3.20.20.70 5 362 1.9E-118 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS12505 504fcf841dbefece226f6856fd26c7f3 374 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 09-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 UA74_RS12505 504fcf841dbefece226f6856fd26c7f3 374 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 360 2.2E-134 T 09-03-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS12505 504fcf841dbefece226f6856fd26c7f3 374 PIRSF PIRSF036915 1 374 8.9E-163 T 09-03-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS22480 af532fee03568433cd6dbc147ab7082f 404 Pfam PF07730 Histidine kinase 187 253 1.2E-14 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS22480 af532fee03568433cd6dbc147ab7082f 404 Gene3D G3DSA:3.30.565.10 294 391 1.0E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS22480 af532fee03568433cd6dbc147ab7082f 404 SUPERFAMILY SSF55874 278 390 4.38E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07410 76964855d0ecf516b00aed61e6915fd5 136 SUPERFAMILY SSF88723 1 118 6.87E-12 T 09-03-2017 IPR029060 PIN domain-like UA74_RS07410 76964855d0ecf516b00aed61e6915fd5 136 Pfam PF01850 PIN domain 2 116 3.4E-12 T 09-03-2017 IPR002716 PIN domain UA74_RS07410 76964855d0ecf516b00aed61e6915fd5 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 127 9.662 T 09-03-2017 IPR022907 VapC family GO:0004540 UA74_RS30325 02bc6064ba9cd0b664f1f56be0d7f2c4 87 Pfam PF00462 Glutaredoxin 4 61 1.5E-13 T 09-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 UA74_RS30325 02bc6064ba9cd0b664f1f56be0d7f2c4 87 SUPERFAMILY SSF52833 4 75 5.51E-14 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS30325 02bc6064ba9cd0b664f1f56be0d7f2c4 87 Gene3D G3DSA:3.40.30.10 3 72 7.4E-17 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 SMART SM00345 19 78 2.0E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 Pfam PF07702 UTRA domain 111 250 2.3E-29 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 3.0E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 3.0E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 Gene3D G3DSA:1.10.10.10 8 78 1.1E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 SMART SM00866 110 251 9.6E-25 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 9.2E-22 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 SUPERFAMILY SSF46785 8 89 7.43E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 SUPERFAMILY SSF64288 66 256 5.23E-37 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS00750 5ee3ff9202d81ee6bf051aa2a4ed757b 259 Gene3D G3DSA:3.40.1410.10 79 254 4.6E-56 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 SUPERFAMILY SSF52540 274 501 1.24E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 Gene3D G3DSA:3.40.50.300 274 504 3.4E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 SUPERFAMILY SSF52540 19 239 7.31E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 Pfam PF00005 ABC transporter 285 441 8.2E-12 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 Pfam PF00005 ABC transporter 36 180 4.1E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 SMART SM00382 43 228 6.2E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS27670 ec83c79b1b9adfefea9c7ba3feb1d4e4 512 Gene3D G3DSA:3.40.50.300 14 248 3.4E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23825 9f9b244b8bf3edaad429d6f03ad4cdd8 414 SMART SM00341 230 310 3.9E-20 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS23825 9f9b244b8bf3edaad429d6f03ad4cdd8 414 SMART SM00474 24 191 7.2E-35 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_RS23825 9f9b244b8bf3edaad429d6f03ad4cdd8 414 Gene3D G3DSA:3.30.420.10 26 204 6.5E-9 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS23825 9f9b244b8bf3edaad429d6f03ad4cdd8 414 SUPERFAMILY SSF47819 211 321 5.89E-25 T 09-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 UA74_RS23825 9f9b244b8bf3edaad429d6f03ad4cdd8 414 SUPERFAMILY SSF53098 15 228 1.9E-51 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS23825 9f9b244b8bf3edaad429d6f03ad4cdd8 414 Pfam PF00570 HRDC domain 234 299 1.1E-13 T 09-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_RS23825 9f9b244b8bf3edaad429d6f03ad4cdd8 414 Pfam PF01612 3'-5' exonuclease 26 190 2.3E-31 T 09-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 SUPERFAMILY SSF52743 184 469 2.09E-79 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 Gene3D G3DSA:3.40.50.200 167 469 5.6E-86 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 1.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 1.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 PRINTS PR00723 Subtilisin serine protease family (S8) signature 238 251 1.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 Gene3D G3DSA:2.60.40.360 475 573 9.9E-5 T 09-03-2017 IPR008962 PapD-like UA74_RS06930 92bbec10d96434815bb96b1a3bd5648d 1080 Pfam PF00082 Subtilase family 200 460 2.3E-55 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 1.2E-45 T 09-03-2017 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.2E-45 T 09-03-2017 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 1.2E-45 T 09-03-2017 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 1.2E-45 T 09-03-2017 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 1.2E-45 T 09-03-2017 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.2E-45 T 09-03-2017 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 SUPERFAMILY SSF51905 277 365 4.26E-59 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 SUPERFAMILY SSF51905 6 183 4.26E-59 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 Gene3D G3DSA:3.50.50.60 278 357 8.4E-54 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 Gene3D G3DSA:3.50.50.60 105 188 8.4E-54 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 Gene3D G3DSA:3.50.50.60 6 71 8.4E-54 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05790 80e51bc650f3df57d4345f5352f32695 537 Pfam PF01494 FAD binding domain 5 355 2.9E-95 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS02010 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 Gene3D G3DSA:1.10.260.40 15 109 1.6E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02010 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 SUPERFAMILY SSF47413 13 75 6.19E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02010 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 Pfam PF01381 Helix-turn-helix 19 71 4.7E-14 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS02010 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 SMART SM00530 18 73 7.8E-14 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 Gene3D G3DSA:2.30.42.10 420 495 8.0E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 SUPERFAMILY SSF50156 379 493 4.86E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 PRINTS PR00834 HtrA/DegQ protease family signature 440 452 2.3E-42 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 PRINTS PR00834 HtrA/DegQ protease family signature 356 373 2.3E-42 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 PRINTS PR00834 HtrA/DegQ protease family signature 294 318 2.3E-42 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 2.3E-42 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 PRINTS PR00834 HtrA/DegQ protease family signature 334 351 2.3E-42 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 PRINTS PR00834 HtrA/DegQ protease family signature 254 274 2.3E-42 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 Pfam PF13180 PDZ domain 409 491 2.3E-10 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 Gene3D G3DSA:2.40.10.10 216 294 2.5E-24 T 09-03-2017 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 Pfam PF13365 Trypsin-like peptidase domain 219 363 5.8E-32 T 09-03-2017 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 SMART SM00228 408 482 2.6E-7 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 Gene3D G3DSA:2.40.10.10 295 413 7.6E-40 T 09-03-2017 UA74_RS04630 e34bb66d175cf9db209d7be4ba1eaff4 497 SUPERFAMILY SSF50494 193 413 1.95E-51 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS16390 d799d319e0092ab7d24f36e626a0ab76 370 Pfam PF09661 Protein of unknown function (DUF2398) 18 360 2.2E-73 T 09-03-2017 IPR013494 Conserved hypothetical protein CHP02678 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 230 466 2.0E-113 T 09-03-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 SUPERFAMILY SSF88946 162 304 8.5E-54 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 SUPERFAMILY SSF88659 307 380 1.8E-22 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Gene3D G3DSA:1.10.10.10 307 358 2.2E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 258 271 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF00140 Sigma-70 factor, region 1.2 165 196 8.9E-16 T 09-03-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 282 290 2.7E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 258 271 2.7E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 442 453 2.7E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 406 418 2.7E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 427 442 2.7E-29 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 230 455 1.9E-35 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 63 467 33.064 T 09-03-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 SUPERFAMILY SSF88659 366 466 2.88E-26 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Gene3D G3DSA:1.10.10.10 397 467 1.3E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF04545 Sigma-70, region 4 402 455 1.3E-18 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF04539 Sigma-70 region 3 313 388 1.5E-28 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 427 453 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Gene3D G3DSA:1.10.601.10 56 303 1.9E-70 T 09-03-2017 UA74_RS08525 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF04542 Sigma-70 region 2 234 303 1.7E-22 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23265 1aead46eb5193e7d87152c1ba091be1e 513 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 9 491 4.4E-60 T 09-03-2017 IPR013381 CRISPR-associated protein Cse1 UA74_RS23265 1aead46eb5193e7d87152c1ba091be1e 513 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 9 472 6.0E-78 T 09-03-2017 IPR013381 CRISPR-associated protein Cse1 UA74_RS01640 84598983abb0b43dbe77fc9c3b9f8130 162 Pfam PF02559 CarD-like/TRCF domain 3 110 8.7E-16 T 09-03-2017 IPR003711 CarD-like/TRCF domain UA74_RS01640 84598983abb0b43dbe77fc9c3b9f8130 162 SUPERFAMILY SSF141259 3 65 3.53E-14 T 09-03-2017 IPR003711 CarD-like/TRCF domain UA74_RS01640 84598983abb0b43dbe77fc9c3b9f8130 162 SMART SM01058 2 112 1.1E-32 T 09-03-2017 IPR003711 CarD-like/TRCF domain UA74_RS03965 458bebc456bff504bf7abdfb5a5fd205 461 Gene3D G3DSA:1.10.510.10 92 284 4.0E-42 T 09-03-2017 UA74_RS03965 458bebc456bff504bf7abdfb5a5fd205 461 Gene3D G3DSA:3.30.200.20 9 91 1.9E-13 T 09-03-2017 UA74_RS03965 458bebc456bff504bf7abdfb5a5fd205 461 Pfam PF00069 Protein kinase domain 16 260 1.5E-38 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS03965 458bebc456bff504bf7abdfb5a5fd205 461 SMART SM00220 15 264 4.7E-42 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS03965 458bebc456bff504bf7abdfb5a5fd205 461 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS03965 458bebc456bff504bf7abdfb5a5fd205 461 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS03965 458bebc456bff504bf7abdfb5a5fd205 461 SUPERFAMILY SSF56112 12 263 2.6E-63 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS26890 82a32cf3f7462ec3a4b438177a55e101 310 Gene3D G3DSA:3.90.25.10 231 284 2.3E-28 T 09-03-2017 UA74_RS26890 82a32cf3f7462ec3a4b438177a55e101 310 SUPERFAMILY SSF51735 6 298 7.19E-82 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26890 82a32cf3f7462ec3a4b438177a55e101 310 Gene3D G3DSA:3.40.50.720 39 205 6.1E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26890 82a32cf3f7462ec3a4b438177a55e101 310 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 6 298 2.1E-85 T 09-03-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 UA74_RS26890 82a32cf3f7462ec3a4b438177a55e101 310 Pfam PF04321 RmlD substrate binding domain 6 299 7.1E-104 T 09-03-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 SUPERFAMILY SSF52343 147 292 4.45E-31 T 09-03-2017 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 352 360 - T 09-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 Gene3D G3DSA:3.40.50.80 149 287 8.4E-35 T 09-03-2017 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 SUPERFAMILY SSF63380 106 156 1.59E-17 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 SUPERFAMILY SSF63380 25 75 1.59E-17 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 Gene3D G3DSA:3.10.20.30 288 403 2.5E-29 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 SUPERFAMILY SSF54292 285 402 6.55E-26 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 322 394 4.4E-12 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 Gene3D G3DSA:2.40.30.10 26 148 1.1E-18 T 09-03-2017 UA74_RS02515 8da6ab573b8411d577813e469943fb58 405 Pfam PF00175 Oxidoreductase NAD-binding domain 168 275 3.4E-14 T 09-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UA74_RS17940 ab4f6f01884a01a5602c841e3b4617e6 208 Gene3D G3DSA:3.40.50.360 5 179 3.4E-31 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS17940 ab4f6f01884a01a5602c841e3b4617e6 208 SUPERFAMILY SSF52218 6 180 2.1E-27 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS17940 ab4f6f01884a01a5602c841e3b4617e6 208 Pfam PF03358 NADPH-dependent FMN reductase 7 156 3.2E-34 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS17940 ab4f6f01884a01a5602c841e3b4617e6 208 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 6 202 6.3E-86 T 09-03-2017 IPR023932 Uncharacterised protein family, CE1759 UA74_RS10870 071672adf226164cb0f3425df6b8f8c4 129 Pfam PF01850 PIN domain 1 115 3.2E-9 T 09-03-2017 IPR002716 PIN domain UA74_RS10870 071672adf226164cb0f3425df6b8f8c4 129 SUPERFAMILY SSF88723 1 121 1.29E-13 T 09-03-2017 IPR029060 PIN domain-like UA74_RS10870 071672adf226164cb0f3425df6b8f8c4 129 Gene3D G3DSA:3.40.50.1010 1 119 4.0E-22 T 09-03-2017 IPR029060 PIN domain-like UA74_RS18375 9c306a3bef329035a6889160e58f2abc 318 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 297 5.3E-44 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS00475 b162595d86a25ec5f3171d1a813e52b8 491 Gene3D G3DSA:3.40.50.300 205 295 2.1E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00475 b162595d86a25ec5f3171d1a813e52b8 491 Gene3D G3DSA:3.40.50.300 17 119 2.1E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00475 b162595d86a25ec5f3171d1a813e52b8 491 SUPERFAMILY SSF52540 15 149 2.17E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00475 b162595d86a25ec5f3171d1a813e52b8 491 SUPERFAMILY SSF52540 179 470 2.17E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00475 b162595d86a25ec5f3171d1a813e52b8 491 Pfam PF13245 Part of AAA domain 35 81 2.2E-8 T 09-03-2017 UA74_RS00475 b162595d86a25ec5f3171d1a813e52b8 491 Gene3D G3DSA:3.40.50.300 296 477 1.8E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17300 8e7d19f407794f65c72db393f415b130 400 SUPERFAMILY SSF53756 3 393 3.4E-69 T 09-03-2017 UA74_RS17300 8e7d19f407794f65c72db393f415b130 400 Gene3D G3DSA:3.40.50.2000 234 374 8.1E-30 T 09-03-2017 UA74_RS17300 8e7d19f407794f65c72db393f415b130 400 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 229 363 8.1E-16 T 09-03-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 UA74_RS17300 8e7d19f407794f65c72db393f415b130 400 Gene3D G3DSA:3.40.50.2000 3 233 1.8E-6 T 09-03-2017 UA74_RS17300 8e7d19f407794f65c72db393f415b130 400 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 3 393 2.7E-109 T 09-03-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 SUPERFAMILY SSF46785 4 87 1.84E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 72 7.8E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 Gene3D G3DSA:3.40.1410.10 72 239 3.5E-39 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 SUPERFAMILY SSF64288 62 239 2.2E-38 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 Pfam PF07702 UTRA domain 97 232 9.2E-31 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 SMART SM00345 15 74 1.8E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-8 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 SMART SM00866 96 233 6.6E-27 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS08785 97dbb6b0ddb4320a3216ae3600246370 293 Gene3D G3DSA:1.10.10.10 4 71 4.6E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 SUPERFAMILY SSF56194 248 389 8.76E-29 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Gene3D G3DSA:3.30.43.10 1 66 2.7E-22 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Pfam PF01565 FAD binding domain 123 190 1.1E-9 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Pfam PF01565 FAD binding domain 16 65 4.2E-7 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 250 388 1.4E-36 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 SUPERFAMILY SSF56176 122 224 3.98E-21 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 392 66.537 T 09-03-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Gene3D G3DSA:3.90.78.10 278 390 6.9E-39 T 09-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Gene3D G3DSA:3.30.465.10 120 228 5.6E-45 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 Gene3D G3DSA:3.30.465.10 262 277 5.6E-45 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS02155 b8cc38c258ae7e1e2f5c80f639683a18 392 SUPERFAMILY SSF56176 2 66 1.09E-10 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 115 3.9E-24 T 09-03-2017 IPR000595 Cyclic nucleotide-binding domain UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 SMART SM00419 167 215 2.2E-13 T 09-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.1E-18 T 09-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 SUPERFAMILY SSF51206 4 142 9.95E-37 T 09-03-2017 IPR018490 Cyclic nucleotide-binding-like UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 SMART SM00100 10 128 3.2E-26 T 09-03-2017 IPR000595 Cyclic nucleotide-binding domain UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 Gene3D G3DSA:1.10.10.10 144 223 2.2E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 Gene3D G3DSA:2.60.120.10 2 142 4.2E-38 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS01225 e73a751bb6f9455834ed90fe24e1fc9a 224 SUPERFAMILY SSF46785 145 223 4.21E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06465 5c7ce19e2d0e95b1ed749339bf7ad939 358 Gene3D G3DSA:3.40.50.150 260 351 4.7E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06465 5c7ce19e2d0e95b1ed749339bf7ad939 358 Gene3D G3DSA:3.40.50.150 66 223 4.7E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06465 5c7ce19e2d0e95b1ed749339bf7ad939 358 Pfam PF08241 Methyltransferase domain 109 206 6.9E-23 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS06465 5c7ce19e2d0e95b1ed749339bf7ad939 358 SUPERFAMILY SSF53335 70 231 4.52E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06465 5c7ce19e2d0e95b1ed749339bf7ad939 358 SUPERFAMILY SSF53335 264 350 4.52E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 306 746 7.7E-159 T 09-03-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 SUPERFAMILY SSF89550 3 75 1.14E-23 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 SUPERFAMILY SSF89550 111 238 1.14E-23 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 Gene3D G3DSA:3.20.20.140 111 260 3.0E-35 T 09-03-2017 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 Gene3D G3DSA:3.20.20.140 4 75 3.0E-35 T 09-03-2017 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 Pfam PF02811 PHP domain 1 184 8.8E-41 T 09-03-2017 IPR004013 PHP domain GO:0003824 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 SMART SM00481 1 58 1.9E-19 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 Pfam PF14579 Helix-hairpin-helix motif 820 908 4.8E-24 T 09-03-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS01445 936f43f0b2302b46ea232386fb579ac4 1172 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 1 1047 0.0 T 09-03-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 Gene3D G3DSA:3.40.190.10 90 177 9.5E-14 T 09-03-2017 UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 Gene3D G3DSA:1.10.10.10 1 81 7.0E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-6 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-6 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-6 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 Pfam PF03466 LysR substrate binding domain 89 292 1.0E-40 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 SUPERFAMILY SSF46785 1 110 7.48E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 SUPERFAMILY SSF53850 89 293 2.44E-38 T 09-03-2017 UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-18 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS24200 a99d5488ffa1ba45d607a14d4ce44bfa 300 Gene3D G3DSA:3.40.190.10 178 262 3.3E-14 T 09-03-2017 UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 09-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 Gene3D G3DSA:3.30.1340.10 1 84 1.5E-19 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 Pfam PF00381 PTS HPr component phosphorylation site 4 83 5.2E-18 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 SUPERFAMILY SSF55594 1 87 8.77E-16 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 1.8E-18 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 PRINTS PR00107 Phosphocarrier protein signature 58 75 2.1E-10 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.1E-10 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS16700 194a3680b296fcd353db2e6128821e55 94 PRINTS PR00107 Phosphocarrier protein signature 43 58 2.1E-10 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS01310 db47741d09f3b42c0311f577c4a27599 310 SUPERFAMILY SSF53697 107 289 4.45E-43 T 09-03-2017 UA74_RS01310 db47741d09f3b42c0311f577c4a27599 310 Gene3D G3DSA:1.10.10.10 16 88 6.9E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01310 db47741d09f3b42c0311f577c4a27599 310 Gene3D G3DSA:3.40.50.10490 121 281 2.1E-41 T 09-03-2017 UA74_RS01310 db47741d09f3b42c0311f577c4a27599 310 SUPERFAMILY SSF46689 15 87 2.33E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS01310 db47741d09f3b42c0311f577c4a27599 310 Pfam PF01418 Helix-turn-helix domain, rpiR family 17 87 3.2E-20 T 09-03-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UA74_RS01310 db47741d09f3b42c0311f577c4a27599 310 Pfam PF01380 SIS domain 142 269 1.4E-27 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS19920 580d402b738a74f51cfa6740696e7092 292 Gene3D G3DSA:3.40.50.10490 170 289 7.7E-25 T 09-03-2017 UA74_RS19920 580d402b738a74f51cfa6740696e7092 292 Gene3D G3DSA:3.40.50.10490 4 147 6.6E-12 T 09-03-2017 UA74_RS19920 580d402b738a74f51cfa6740696e7092 292 SUPERFAMILY SSF53697 5 289 2.52E-36 T 09-03-2017 UA74_RS26105 3f293d6f5c7703e487568ccc4f1fd2da 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 317 9.9E-87 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS26105 3f293d6f5c7703e487568ccc4f1fd2da 354 SMART SM01329 2 334 8.9E-158 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS26105 3f293d6f5c7703e487568ccc4f1fd2da 354 Gene3D G3DSA:3.40.718.10 2 319 1.3E-111 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS26105 3f293d6f5c7703e487568ccc4f1fd2da 354 SUPERFAMILY SSF53659 2 329 1.73E-106 T 09-03-2017 UA74_RS26105 3f293d6f5c7703e487568ccc4f1fd2da 354 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 338 56.913 T 09-03-2017 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 UA74_RS26105 3f293d6f5c7703e487568ccc4f1fd2da 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 09-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 Pfam PF01084 Ribosomal protein S18 26 75 2.9E-23 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 80 20.045 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 6.2E-16 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 6.2E-16 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 6.2E-16 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 6.2E-16 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 SUPERFAMILY SSF46911 5 79 2.49E-24 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 79 2.3E-27 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 09-03-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 Gene3D G3DSA:4.10.640.10 11 79 1.4E-28 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30175 bee95d21e95e9924b7900939b36f5035 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 79 5.0E-22 T 09-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.63 T 09-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 Gene3D G3DSA:3.40.50.790 69 159 9.3E-42 T 09-03-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 Pfam PF00687 Ribosomal protein L1p/L10e family 32 220 1.8E-50 T 09-03-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 09-03-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 SUPERFAMILY SSF56808 6 227 2.35E-80 T 09-03-2017 IPR023674 Ribosomal protein L1-like UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 4.0E-100 T 09-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 PIRSF PIRSF002155 1 227 1.7E-73 T 09-03-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 Gene3D G3DSA:3.30.190.20 161 226 9.7E-44 T 09-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 UA74_RS02830 d119e23912e9787937d34a911a6cf691 239 Gene3D G3DSA:3.30.190.20 17 68 9.7E-44 T 09-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 UA74_RS18745 4dc1d4927811821f664b69062296b667 262 Pfam PF00227 Proteasome subunit 46 226 5.2E-37 T 09-03-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 UA74_RS18745 4dc1d4927811821f664b69062296b667 262 Gene3D G3DSA:3.60.20.10 45 252 1.4E-48 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS18745 4dc1d4927811821f664b69062296b667 262 SUPERFAMILY SSF56235 36 256 6.92E-53 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS18745 4dc1d4927811821f664b69062296b667 262 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 46 257 4.6E-93 T 09-03-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UA74_RS18745 4dc1d4927811821f664b69062296b667 262 PRINTS PR00141 Proteasome component signature 56 71 2.1E-5 T 09-03-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 UA74_RS18745 4dc1d4927811821f664b69062296b667 262 PRINTS PR00141 Proteasome component signature 194 205 2.1E-5 T 09-03-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 UA74_RS18745 4dc1d4927811821f664b69062296b667 262 PRINTS PR00141 Proteasome component signature 183 194 2.1E-5 T 09-03-2017 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 UA74_RS21110 f68ba2732199e80a7fe54b91368eaa53 410 SUPERFAMILY SSF56796 27 379 1.44E-75 T 09-03-2017 UA74_RS21110 f68ba2732199e80a7fe54b91368eaa53 410 Gene3D G3DSA:1.20.1090.10 192 379 2.0E-35 T 09-03-2017 UA74_RS21110 f68ba2732199e80a7fe54b91368eaa53 410 Gene3D G3DSA:3.40.50.1970 19 191 4.7E-46 T 09-03-2017 UA74_RS21110 f68ba2732199e80a7fe54b91368eaa53 410 Pfam PF01761 3-dehydroquinate synthase 86 344 7.8E-62 T 09-03-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF54980 408 503 7.67E-23 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 TIGRFAM TIGR01393 lepA: elongation factor 4 14 604 1.2E-290 T 09-03-2017 IPR006297 Elongation factor 4 GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 282.621 T 09-03-2017 IPR006297 Elongation factor 4 GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF54980 301 380 3.2E-19 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 SMART SM00838 407 491 5.7E-4 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF03144 Elongation factor Tu domain 2 215 285 2.9E-7 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:3.30.70.240 410 499 2.3E-19 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF00679 Elongation factor G C-terminus 408 494 4.5E-22 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF52540 9 214 1.1E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:3.40.50.300 11 203 9.9E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF06421 GTP-binding protein LepA C-terminus 498 602 1.1E-48 T 09-03-2017 IPR013842 GTP-binding protein LepA, C-terminal UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 185 1.7E-16 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.2E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.2E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.2E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.2E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 17 30 3.2E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:3.30.70.870 301 378 2.1E-25 T 09-03-2017 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF00009 Elongation factor Tu GTP binding domain 15 191 4.4E-50 T 09-03-2017 UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF50447 176 297 4.29E-24 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS08630 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:2.40.30.10 204 298 1.5E-19 T 09-03-2017 UA74_RS00515 555cea3383ed0f582bd2226081370552 394 Gene3D G3DSA:2.60.120.10 228 365 7.1E-35 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS00515 555cea3383ed0f582bd2226081370552 394 Pfam PF04209 homogentisate 1,2-dioxygenase 15 385 6.4E-17 T 09-03-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 UA74_RS00515 555cea3383ed0f582bd2226081370552 394 SUPERFAMILY SSF51182 6 386 3.73E-89 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS00515 555cea3383ed0f582bd2226081370552 394 Gene3D G3DSA:2.60.120.10 96 176 6.8E-10 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 Gene3D G3DSA:3.40.630.10 23 237 3.5E-94 T 09-03-2017 UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 Gene3D G3DSA:3.40.630.10 357 415 3.5E-94 T 09-03-2017 UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 Pfam PF01546 Peptidase family M20/M25/M40 88 412 3.7E-27 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 PIRSF PIRSF001235 16 415 8.1E-118 T 09-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 SUPERFAMILY SSF53187 31 234 1.0E-67 T 09-03-2017 UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 SUPERFAMILY SSF53187 342 415 1.0E-67 T 09-03-2017 UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 25 411 8.9E-86 T 09-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 SUPERFAMILY SSF55031 226 334 3.14E-22 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS26505 132aa6b4f27e70a78b28f01e5402dc81 415 Gene3D G3DSA:3.30.70.360 238 337 6.6E-30 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS23015 d4be601a43595a4565498943f3bc733f 788 Pfam PF00656 Caspase domain 8 299 1.8E-21 T 09-03-2017 UA74_RS23015 d4be601a43595a4565498943f3bc733f 788 Gene3D G3DSA:3.40.50.1460 6 302 2.9E-16 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS23015 d4be601a43595a4565498943f3bc733f 788 SUPERFAMILY SSF52129 226 289 9.54E-17 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS23015 d4be601a43595a4565498943f3bc733f 788 SUPERFAMILY SSF52129 1 148 9.54E-17 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 SUPERFAMILY SSF54675 14 120 4.94E-27 T 09-03-2017 UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 31 119 1.0E-21 T 09-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 121 288 4.5E-53 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 19 288 3.1E-85 T 09-03-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 Gene3D G3DSA:3.20.20.70 142 279 2.8E-52 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 PIRSF PIRSF006250 12 290 3.0E-90 T 09-03-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 SUPERFAMILY SSF51690 121 289 5.1E-52 T 09-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UA74_RS09930 47cf22e318ed378458bde21866fe717e 290 Gene3D G3DSA:3.90.1170.20 9 141 7.4E-43 T 09-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 UA74_RS21950 34741835ce1270c25efa7d80b507bdb0 326 SUPERFAMILY SSF51679 1 322 2.06E-61 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS21950 34741835ce1270c25efa7d80b507bdb0 326 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 322 1.9E-139 T 09-03-2017 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related UA74_RS21950 34741835ce1270c25efa7d80b507bdb0 326 Pfam PF00296 Luciferase-like monooxygenase 3 294 3.8E-50 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS21950 34741835ce1270c25efa7d80b507bdb0 326 Gene3D G3DSA:3.20.20.30 2 322 8.1E-65 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 SUPERFAMILY SSF49503 406 512 6.19E-25 T 09-03-2017 IPR008972 Cupredoxin UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 Gene3D G3DSA:2.60.40.420 57 208 4.0E-28 T 09-03-2017 IPR008972 Cupredoxin UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 Gene3D G3DSA:2.60.40.420 386 513 1.1E-31 T 09-03-2017 IPR008972 Cupredoxin UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 Gene3D G3DSA:2.60.40.420 209 342 1.0E-30 T 09-03-2017 IPR008972 Cupredoxin UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 Pfam PF07732 Multicopper oxidase 81 206 2.3E-16 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 Pfam PF07731 Multicopper oxidase 409 514 1.5E-20 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 SUPERFAMILY SSF49503 210 345 1.31E-22 T 09-03-2017 IPR008972 Cupredoxin UA74_RS20330 2db996baaacad36034b71942b9af14d9 516 SUPERFAMILY SSF49503 59 207 4.75E-25 T 09-03-2017 IPR008972 Cupredoxin UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 Pfam PF07731 Multicopper oxidase 369 483 8.8E-23 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 Gene3D G3DSA:2.60.40.420 328 481 6.4E-34 T 09-03-2017 IPR008972 Cupredoxin UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 SUPERFAMILY SSF49503 52 177 4.6E-33 T 09-03-2017 IPR008972 Cupredoxin UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 SUPERFAMILY SSF49503 184 309 7.5E-23 T 09-03-2017 IPR008972 Cupredoxin UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 SUPERFAMILY SSF49503 373 481 2.57E-29 T 09-03-2017 IPR008972 Cupredoxin UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 Pfam PF07732 Multicopper oxidase 63 177 2.4E-32 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 ProSitePatterns PS00080 Multicopper oxidases signature 2. 464 475 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 Gene3D G3DSA:2.60.40.420 49 183 6.9E-34 T 09-03-2017 IPR008972 Cupredoxin UA74_RS24155 58bdb809dbf9d7c86ec06386cfb5f938 496 Gene3D G3DSA:2.60.40.420 184 301 2.6E-28 T 09-03-2017 IPR008972 Cupredoxin UA74_RS14815 c8df0fe64fdc4eb8da909c1f7a4e148e 266 Pfam PF00535 Glycosyl transferase family 2 20 188 4.1E-33 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS14815 c8df0fe64fdc4eb8da909c1f7a4e148e 266 Gene3D G3DSA:3.90.550.10 17 236 1.4E-30 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS14815 c8df0fe64fdc4eb8da909c1f7a4e148e 266 SUPERFAMILY SSF53448 15 236 2.05E-48 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 23 359 3.9E-68 T 09-03-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 Gene3D G3DSA:1.10.10.10 439 496 1.0E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 Gene3D G3DSA:3.40.50.300 217 363 6.4E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 SMART SM00490 262 343 9.0E-21 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 Pfam PF00270 DEAD/DEAH box helicase 27 196 2.8E-15 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 Gene3D G3DSA:3.40.50.2020 608 694 1.5E-6 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 SUPERFAMILY SSF53271 651 700 3.41E-8 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 Gene3D G3DSA:3.40.50.300 22 204 2.0E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 Pfam PF00271 Helicase conserved C-terminal domain 250 342 9.0E-12 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 SMART SM00487 20 221 4.4E-21 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS08330 f05f13cf5a22f90df46ead92600a5780 703 SUPERFAMILY SSF52540 68 363 7.51E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12995 8cde877bea57ba0b211cd4ae9873af40 161 SUPERFAMILY SSF52402 11 151 3.77E-24 T 09-03-2017 UA74_RS12995 8cde877bea57ba0b211cd4ae9873af40 161 Pfam PF00582 Universal stress protein family 11 147 3.2E-18 T 09-03-2017 IPR006016 UspA GO:0006950 UA74_RS12995 8cde877bea57ba0b211cd4ae9873af40 161 Gene3D G3DSA:3.40.50.620 11 147 1.7E-25 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS12995 8cde877bea57ba0b211cd4ae9873af40 161 PRINTS PR01438 Universal stress protein signature 8 26 2.5E-9 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS12995 8cde877bea57ba0b211cd4ae9873af40 161 PRINTS PR01438 Universal stress protein signature 125 147 2.5E-9 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS09420 ac440d5473a5d746f29bffc80cdc9e7c 445 Gene3D G3DSA:1.20.1250.20 220 405 1.0E-14 T 09-03-2017 UA74_RS09420 ac440d5473a5d746f29bffc80cdc9e7c 445 SUPERFAMILY SSF103473 5 413 2.62E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS09420 ac440d5473a5d746f29bffc80cdc9e7c 445 Pfam PF07690 Major Facilitator Superfamily 19 287 3.2E-28 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS09420 ac440d5473a5d746f29bffc80cdc9e7c 445 Gene3D G3DSA:1.20.1250.20 8 194 6.0E-28 T 09-03-2017 UA74_RS23075 dbdc2eaad389833ca7b853ad33303bc7 401 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 76 222 1.4E-26 T 09-03-2017 UA74_RS23075 dbdc2eaad389833ca7b853ad33303bc7 401 Gene3D G3DSA:3.40.50.150 25 256 4.0E-52 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23075 dbdc2eaad389833ca7b853ad33303bc7 401 SUPERFAMILY SSF53335 82 224 3.04E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23075 dbdc2eaad389833ca7b853ad33303bc7 401 SUPERFAMILY SSF53335 23 52 3.04E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19705 004ef9a96c6fb2db8b10b6c76ec0ea06 291 SUPERFAMILY SSF81345 2 261 2.35E-36 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS19705 004ef9a96c6fb2db8b10b6c76ec0ea06 291 Gene3D G3DSA:1.10.3470.10 46 261 6.0E-6 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS19705 004ef9a96c6fb2db8b10b6c76ec0ea06 291 Pfam PF00950 ABC 3 transport family 11 264 6.4E-65 T 09-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_RS12590 5e8d175aba4106d2615a8f0cf8767fd4 265 Pfam PF01061 ABC-2 type transporter 26 231 3.5E-18 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS12590 5e8d175aba4106d2615a8f0cf8767fd4 265 PIRSF PIRSF006648 8 264 9.0E-20 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS30420 f7088e7cba2f9452eca05e236fdb653b 440 Pfam PF00155 Aminotransferase class I and II 61 407 1.4E-40 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS30420 f7088e7cba2f9452eca05e236fdb653b 440 Gene3D G3DSA:3.90.1150.10 294 412 4.1E-16 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS30420 f7088e7cba2f9452eca05e236fdb653b 440 Gene3D G3DSA:3.40.640.10 76 293 6.6E-75 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS30420 f7088e7cba2f9452eca05e236fdb653b 440 SUPERFAMILY SSF53383 23 413 9.18E-108 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS21930 075c4233183abef61a9f317d54b5113f 263 Pfam PF00190 Cupin 40 105 8.0E-6 T 09-03-2017 IPR006045 Cupin 1 GO:0045735 UA74_RS21930 075c4233183abef61a9f317d54b5113f 263 Gene3D G3DSA:2.60.120.10 33 105 2.5E-11 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS21930 075c4233183abef61a9f317d54b5113f 263 SUPERFAMILY SSF51182 19 120 1.89E-13 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 SUPERFAMILY SSF48452 235 304 9.79E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 SUPERFAMILY SSF48452 354 407 9.79E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 Pfam PF13560 Helix-turn-helix domain 9 66 1.3E-8 T 09-03-2017 UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 Gene3D G3DSA:1.10.260.40 9 63 9.0E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 Gene3D G3DSA:1.25.40.10 347 406 4.1E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 Gene3D G3DSA:1.25.40.10 197 304 4.1E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 SUPERFAMILY SSF47413 9 63 5.07E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05165 65f00b90ff40b13a64382cc08281db13 422 SMART SM00530 8 63 0.0011 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS10640 10b1188b94ab7cdf063dec694280b713 702 Pfam PF01032 FecCD transport family 392 696 3.0E-83 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS10640 10b1188b94ab7cdf063dec694280b713 702 Pfam PF01032 FecCD transport family 39 352 1.3E-68 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS10640 10b1188b94ab7cdf063dec694280b713 702 SUPERFAMILY SSF81345 22 352 8.24E-58 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS10640 10b1188b94ab7cdf063dec694280b713 702 Gene3D G3DSA:1.10.3470.10 25 354 4.7E-76 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS10640 10b1188b94ab7cdf063dec694280b713 702 Gene3D G3DSA:1.10.3470.10 377 698 3.9E-88 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS10640 10b1188b94ab7cdf063dec694280b713 702 SUPERFAMILY SSF81345 377 696 2.88E-72 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 75 316 9.4E-63 T 09-03-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 SMART SM00967 76 152 6.9E-17 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 77 151 2.1E-14 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 Gene3D G3DSA:3.40.1280.10 163 317 4.8E-52 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 Gene3D G3DSA:3.30.1330.30 71 148 1.1E-19 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 Pfam PF00588 SpoU rRNA Methylase family 169 309 1.5E-35 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 SUPERFAMILY SSF55315 73 149 1.29E-14 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS01665 dc6c74947501508c60a986e8fe12ece1 319 SUPERFAMILY SSF75217 140 317 4.45E-44 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Pfam PF02018 Carbohydrate binding domain 36 156 9.1E-16 T 09-03-2017 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF49384 759 864 4.46E-32 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:2.60.40.290 763 864 9.7E-35 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 829 842 - T 09-03-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF81296 185 273 2.45E-21 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:2.60.40.10 184 273 1.1E-28 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Pfam PF00553 Cellulose binding domain 764 864 2.7E-32 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 SMART SM00637 764 864 1.3E-38 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:1.50.10.10 277 748 4.7E-150 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:2.60.120.260 36 172 2.6E-36 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS07420 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF49785 33 172 2.38E-35 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Pfam PF02927 Cellulase N-terminal ig-like domain 184 266 2.1E-22 T 09-03-2017 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF48208 276 748 4.47E-127 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 719 737 - T 09-03-2017 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS07420 43960b67cd380d229a938ea78835882b 865 Pfam PF00759 Glycosyl hydrolase family 9 277 742 9.2E-100 T 09-03-2017 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS18810 503fecbf05f3c2cc8c40acbcce9e7374 324 Gene3D G3DSA:3.20.20.140 24 183 4.0E-11 T 09-03-2017 UA74_RS18810 503fecbf05f3c2cc8c40acbcce9e7374 324 SUPERFAMILY SSF51556 33 248 4.23E-25 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS18810 503fecbf05f3c2cc8c40acbcce9e7374 324 Gene3D G3DSA:3.20.20.140 190 249 4.5E-10 T 09-03-2017 UA74_RS18810 503fecbf05f3c2cc8c40acbcce9e7374 324 Pfam PF04909 Amidohydrolase 191 248 1.9E-6 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 Gene3D G3DSA:1.10.1660.10 65 122 1.7E-9 T 09-03-2017 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 Pfam PF13411 MerR HTH family regulatory protein 10 78 7.5E-18 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 SMART SM00422 10 79 2.2E-33 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 Gene3D G3DSA:1.10.1660.10 8 64 2.2E-26 T 09-03-2017 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 ProSitePatterns PS00552 MerR-type HTH domain signature. 13 35 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 SUPERFAMILY SSF46955 10 122 2.16E-27 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 6.9E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 6.9E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS10540 86bfbc0356b54c32f229d8568b31cb24 139 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 6.9E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 Gene3D G3DSA:1.10.540.10 2 119 6.8E-39 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 1.6E-20 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 SUPERFAMILY SSF56645 2 246 7.33E-77 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 SUPERFAMILY SSF47203 231 381 1.61E-50 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 Gene3D G3DSA:2.40.110.10 122 221 1.0E-34 T 09-03-2017 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 2.2E-48 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 4.7E-34 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS26360 df343af2434d73a86cae344bc4e0f170 385 Gene3D G3DSA:1.20.140.10 222 381 3.6E-66 T 09-03-2017 UA74_RS26995 2ec33be41b8993f8808585859a688203 1134 Gene3D G3DSA:1.10.1740.10 8 109 3.5E-19 T 09-03-2017 UA74_RS26995 2ec33be41b8993f8808585859a688203 1134 Pfam PF04542 Sigma-70 region 2 31 99 1.9E-12 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26995 2ec33be41b8993f8808585859a688203 1134 SUPERFAMILY SSF88946 8 107 1.57E-17 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26995 2ec33be41b8993f8808585859a688203 1134 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 184 3.3E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26995 2ec33be41b8993f8808585859a688203 1134 Gene3D G3DSA:1.10.10.10 125 184 2.3E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26995 2ec33be41b8993f8808585859a688203 1134 SUPERFAMILY SSF88659 123 184 6.17E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26995 2ec33be41b8993f8808585859a688203 1134 Pfam PF13490 Putative zinc-finger 198 232 1.6E-7 T 09-03-2017 IPR027383 Putative zinc-finger UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 SMART SM00220 12 267 1.8E-59 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 SUPERFAMILY SSF56112 4 268 3.64E-71 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 Gene3D G3DSA:3.30.200.20 3 81 1.8E-25 T 09-03-2017 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 356 368 7.6E-9 T 09-03-2017 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 415 431 7.6E-9 T 09-03-2017 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 462 487 7.6E-9 T 09-03-2017 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 296 308 7.6E-9 T 09-03-2017 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 438 455 7.6E-9 T 09-03-2017 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 Gene3D G3DSA:1.10.510.10 82 264 1.3E-46 T 09-03-2017 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS20350 c1f3c91da6d09b2baaa8e7aced46e3ed 521 Pfam PF00069 Protein kinase domain 12 263 6.6E-48 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS17290 43cd948aebad2444b9f44b6509b1d303 422 Pfam PF06722 Protein of unknown function (DUF1205) 203 303 5.4E-24 T 09-03-2017 IPR010610 Domain of unknown function DUF1205 UA74_RS17290 43cd948aebad2444b9f44b6509b1d303 422 TIGRFAM TIGR04516 glycosyl_450act: glycosyltransferase, activator-dependent family 1 418 1.9E-162 T 09-03-2017 IPR030953 Glycosyltransferase, activator-dependent family GO:0016757 UA74_RS17290 43cd948aebad2444b9f44b6509b1d303 422 Gene3D G3DSA:3.40.50.2000 242 397 3.1E-29 T 09-03-2017 UA74_RS17290 43cd948aebad2444b9f44b6509b1d303 422 SUPERFAMILY SSF53756 1 56 1.02E-86 T 09-03-2017 UA74_RS17290 43cd948aebad2444b9f44b6509b1d303 422 SUPERFAMILY SSF53756 83 414 1.02E-86 T 09-03-2017 UA74_RS17290 43cd948aebad2444b9f44b6509b1d303 422 Gene3D G3DSA:3.40.50.2000 1 241 5.2E-41 T 09-03-2017 UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 Gene3D G3DSA:3.30.230.40 91 199 4.1E-31 T 09-03-2017 UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 09-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 09-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 199 40.597 T 09-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 Gene3D G3DSA:3.30.230.40 3 90 1.8E-36 T 09-03-2017 UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 SUPERFAMILY SSF54211 88 184 3.79E-28 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 179 4.7E-59 T 09-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_RS10010 2126820cdf08e68535a5aa10126b5953 199 SUPERFAMILY SSF54211 3 86 4.68E-31 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS24985 53d2cfe6dfac961a5c7e3c0a1af15381 154 SUPERFAMILY SSF55961 4 146 1.48E-27 T 09-03-2017 UA74_RS24985 53d2cfe6dfac961a5c7e3c0a1af15381 154 Gene3D G3DSA:3.30.530.20 6 145 4.4E-14 T 09-03-2017 IPR023393 START-like domain UA74_RS24985 53d2cfe6dfac961a5c7e3c0a1af15381 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 145 2.3E-12 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS03875 24c235c1f56d7b4afd4889b57a9c5392 255 SUPERFAMILY SSF55781 72 251 4.38E-51 T 09-03-2017 IPR029016 GAF domain-like UA74_RS03875 24c235c1f56d7b4afd4889b57a9c5392 255 SMART SM00346 5 96 1.9E-16 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS03875 24c235c1f56d7b4afd4889b57a9c5392 255 Pfam PF01614 Bacterial transcriptional regulator 124 248 1.9E-33 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS03875 24c235c1f56d7b4afd4889b57a9c5392 255 SUPERFAMILY SSF46785 5 79 2.49E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03875 24c235c1f56d7b4afd4889b57a9c5392 255 Pfam PF09339 IclR helix-turn-helix domain 7 58 1.4E-16 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS03875 24c235c1f56d7b4afd4889b57a9c5392 255 Gene3D G3DSA:1.10.10.10 5 69 1.2E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03875 24c235c1f56d7b4afd4889b57a9c5392 255 Gene3D G3DSA:3.30.450.40 79 251 1.2E-57 T 09-03-2017 IPR029016 GAF domain-like UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 Gene3D G3DSA:2.60.120.260 414 520 1.5E-33 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 Gene3D G3DSA:2.60.120.260 567 648 1.5E-33 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 398 641 1.4E-29 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 99 371 2.5E-39 T 09-03-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 Gene3D G3DSA:3.40.50.1820 80 267 1.1E-47 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 Gene3D G3DSA:3.40.50.1820 326 413 1.1E-47 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 SUPERFAMILY SSF53474 67 421 1.68E-61 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 SMART SM00939 386 644 2.4E-36 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS06210 c4a4065ff458e5725b25b9675af005d7 670 SUPERFAMILY SSF49785 465 649 4.68E-27 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS24705 33512a20946a24155e2301b3a2315b9a 321 SUPERFAMILY SSF51735 128 289 1.09E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24705 33512a20946a24155e2301b3a2315b9a 321 Gene3D G3DSA:3.90.180.10 14 162 2.1E-29 T 09-03-2017 IPR011032 GroES-like UA74_RS24705 33512a20946a24155e2301b3a2315b9a 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 123 5.9E-5 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS24705 33512a20946a24155e2301b3a2315b9a 321 Gene3D G3DSA:3.40.50.720 163 268 1.8E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24705 33512a20946a24155e2301b3a2315b9a 321 SMART SM00829 13 319 7.6E-14 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS24705 33512a20946a24155e2301b3a2315b9a 321 SUPERFAMILY SSF50129 13 156 7.23E-30 T 09-03-2017 IPR011032 GroES-like UA74_RS24705 33512a20946a24155e2301b3a2315b9a 321 Pfam PF00107 Zinc-binding dehydrogenase 167 282 2.0E-23 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 1.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 97 1.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 117 1.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 81 1.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 Pfam PF12802 MarR family 47 105 1.5E-12 T 09-03-2017 UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 Gene3D G3DSA:1.10.10.10 9 154 4.5E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 SUPERFAMILY SSF46785 24 154 1.4E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29760 6b2bccaabe77a81237f678ecacfed54f 155 SMART SM00347 41 141 4.4E-16 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 SUPERFAMILY SSF52540 194 273 7.34E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 SUPERFAMILY SSF52540 518 764 7.34E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 SUPERFAMILY SSF52540 370 392 7.34E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 Pfam PF13245 Part of AAA domain 208 276 2.8E-15 T 09-03-2017 UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 Gene3D G3DSA:3.40.50.300 195 303 1.5E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 Gene3D G3DSA:3.40.50.300 514 612 1.5E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 Gene3D G3DSA:3.40.50.300 613 773 6.5E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23490 bf98ffdfd16805a4917385aa53484962 782 Pfam PF13538 UvrD-like helicase C-terminal domain 712 759 2.7E-8 T 09-03-2017 IPR027785 UvrD-like helicase C-terminal domain UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 Pfam PF00106 short chain dehydrogenase 6 210 6.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 7.6E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 7.6E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 7.6E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 Gene3D G3DSA:3.40.50.720 4 249 8.9E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 4.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 4.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 4.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09860 b479f039ec9383fea165c3510930bbe0 249 SUPERFAMILY SSF51735 3 246 5.76E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17665 d727fd040a8b531797f03da052b37fe3 470 SUPERFAMILY SSF51905 11 192 2.04E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17665 d727fd040a8b531797f03da052b37fe3 470 SUPERFAMILY SSF51905 310 381 2.04E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17665 d727fd040a8b531797f03da052b37fe3 470 Pfam PF00890 FAD binding domain 77 202 5.0E-5 T 09-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS17665 d727fd040a8b531797f03da052b37fe3 470 Gene3D G3DSA:3.50.50.60 314 335 1.2E-16 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17665 d727fd040a8b531797f03da052b37fe3 470 Gene3D G3DSA:3.50.50.60 11 73 1.2E-16 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17665 d727fd040a8b531797f03da052b37fe3 470 Gene3D G3DSA:3.50.50.60 107 199 1.2E-16 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 Pfam PF00005 ABC transporter 376 524 1.0E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 SUPERFAMILY SSF52540 353 595 3.11E-86 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 Pfam PF00664 ABC transporter transmembrane region 37 312 1.0E-58 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 Gene3D G3DSA:1.20.1560.10 24 343 1.7E-88 T 09-03-2017 UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 SUPERFAMILY SSF90123 18 346 1.83E-85 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 Gene3D G3DSA:3.40.50.300 359 588 7.3E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10435 3897bb102424cdd171fbd662583337a6 603 SMART SM00382 384 576 3.7E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS25950 6d07d7988428affa894e1f7033edc284 131 SUPERFAMILY SSF46785 7 86 8.67E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS25950 6d07d7988428affa894e1f7033edc284 131 SMART SM00345 18 77 7.8E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS25950 6d07d7988428affa894e1f7033edc284 131 Gene3D G3DSA:1.10.10.10 5 78 1.2E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS25950 6d07d7988428affa894e1f7033edc284 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 3.0E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 Pfam PF00005 ABC transporter 353 481 1.8E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 Pfam PF00005 ABC transporter 18 197 3.3E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 SMART SM00382 26 242 7.6E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 SMART SM00382 360 527 1.3E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 Pfam PF12848 ABC transporter 240 307 2.6E-8 T 09-03-2017 IPR032781 ABC-transporter extension domain UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 Gene3D G3DSA:3.40.50.300 337 526 6.5E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 Gene3D G3DSA:3.40.50.300 3 99 1.4E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 Gene3D G3DSA:3.40.50.300 136 293 1.4E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 SUPERFAMILY SSF52540 3 239 5.24E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12710 83b93327a141c6a8f8f10d1a7d309a62 542 SUPERFAMILY SSF52540 317 527 1.52E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21535 3309a8a571caf50884e98cf2cc2fc3fb 301 Gene3D G3DSA:1.10.150.130 2 99 3.6E-25 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS21535 3309a8a571caf50884e98cf2cc2fc3fb 301 Pfam PF00589 Phage integrase family 112 281 1.2E-45 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS21535 3309a8a571caf50884e98cf2cc2fc3fb 301 SUPERFAMILY SSF56349 105 295 6.18E-54 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS21535 3309a8a571caf50884e98cf2cc2fc3fb 301 SUPERFAMILY SSF47823 3 95 2.16E-15 T 09-03-2017 IPR010998 Integrase, Lambda-type, N-terminal UA74_RS21535 3309a8a571caf50884e98cf2cc2fc3fb 301 Gene3D G3DSA:1.10.443.10 111 290 4.3E-57 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS21535 3309a8a571caf50884e98cf2cc2fc3fb 301 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 1 89 2.5E-20 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_RS21535 3309a8a571caf50884e98cf2cc2fc3fb 301 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 297 53.853 T 09-03-2017 IPR023009 Tyrosine recombinase XerC/XerD UA74_RS23045 1776e8f3c2aff3cbcce4ba0ae0f80264 142 SMART SM00960 10 100 1.7E-29 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS23045 1776e8f3c2aff3cbcce4ba0ae0f80264 142 Pfam PF03259 Roadblock/LC7 domain 9 100 2.2E-25 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS23045 1776e8f3c2aff3cbcce4ba0ae0f80264 142 Gene3D G3DSA:3.30.450.30 5 126 1.6E-28 T 09-03-2017 UA74_RS23045 1776e8f3c2aff3cbcce4ba0ae0f80264 142 SUPERFAMILY SSF103196 2 129 2.44E-35 T 09-03-2017 UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 Gene3D G3DSA:3.40.50.720 147 259 1.2E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 SUPERFAMILY SSF51735 111 269 5.19E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 Gene3D G3DSA:3.90.180.10 1 146 5.6E-46 T 09-03-2017 IPR011032 GroES-like UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 327 1.6E-135 T 09-03-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 Pfam PF00107 Zinc-binding dehydrogenase 151 265 1.6E-27 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 SUPERFAMILY SSF50129 1 138 2.52E-38 T 09-03-2017 IPR011032 GroES-like UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 SMART SM00829 10 326 2.3E-43 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS00715 b44667b02afaf8212d97d424d76f1ef5 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 2.5E-9 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:3.40.50.300 26 130 4.8E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:3.40.50.300 223 327 4.8E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Pfam PF00580 UvrD/REP helicase N-terminal domain 30 313 3.3E-74 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Pfam PF13361 UvrD-like helicase C-terminal domain 319 690 4.0E-64 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:3.40.50.300 628 719 2.3E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:3.40.50.300 328 430 2.3E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 26 821 9.1E-281 T 09-03-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:1.10.10.160 145 222 1.1E-24 T 09-03-2017 IPR013986 DExx box DNA helicase domain UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 SUPERFAMILY SSF52540 598 718 1.3E-168 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 SUPERFAMILY SSF52540 26 565 1.3E-168 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:1.10.486.10 431 565 3.4E-47 T 09-03-2017 UA74_RS27935 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:1.10.486.10 598 616 3.4E-47 T 09-03-2017 UA74_RS14330 2146ff289c19b919c30576908ca22b62 423 SUPERFAMILY SSF142764 5 422 3.14E-105 T 09-03-2017 UA74_RS14330 2146ff289c19b919c30576908ca22b62 423 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 254 415 5.8E-33 T 09-03-2017 IPR031475 Putative nucleotide-binding C-terminal domain UA74_RS14330 2146ff289c19b919c30576908ca22b62 423 Pfam PF07005 Putative sugar-binding N-terminal domain 5 229 1.3E-65 T 09-03-2017 IPR010737 Putative sugar-binding, N-terminal domain UA74_RS10895 f07b8519d7c5be3568f99ca3ffb1744e 206 SUPERFAMILY SSF52317 6 203 7.99E-45 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS10895 f07b8519d7c5be3568f99ca3ffb1744e 206 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 09-03-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10895 f07b8519d7c5be3568f99ca3ffb1744e 206 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 7 200 1.5E-68 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10895 f07b8519d7c5be3568f99ca3ffb1744e 206 Gene3D G3DSA:3.40.50.880 5 205 1.3E-74 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS10895 f07b8519d7c5be3568f99ca3ffb1744e 206 Pfam PF01174 SNO glutamine amidotransferase family 9 203 6.6E-54 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10895 f07b8519d7c5be3568f99ca3ffb1744e 206 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 202 37.632 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10895 f07b8519d7c5be3568f99ca3ffb1744e 206 PIRSF PIRSF005639 1 206 3.5E-68 T 09-03-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 Pfam PF07478 D-ala D-ala ligase C-terminus 148 313 2.8E-47 T 09-03-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 316 31.605 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 Gene3D G3DSA:3.30.470.20 103 121 2.7E-38 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 Gene3D G3DSA:3.30.470.20 188 314 2.7E-38 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 Pfam PF01820 D-ala D-ala ligase N-terminus 4 104 8.3E-20 T 09-03-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 Gene3D G3DSA:3.40.50.20 2 99 3.2E-19 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 259 286 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 PIRSF PIRSF039102 1 318 7.5E-74 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 315 2.7E-75 T 09-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 SUPERFAMILY SSF56059 114 318 6.68E-45 T 09-03-2017 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 SUPERFAMILY SSF52440 1 113 1.25E-22 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 Gene3D G3DSA:3.30.1490.20 125 187 1.0E-14 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS19320 302c9ae453a57058e492f7bd5450f6b8 330 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 81 92 - T 09-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 Gene3D G3DSA:3.40.50.1820 7 159 7.8E-69 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 Gene3D G3DSA:3.40.50.1820 218 303 7.8E-69 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 SMART SM00939 291 557 5.0E-76 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 20 513 7.2E-58 T 09-03-2017 IPR005674 CocE/Serine esterase GO:0016787 UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 SUPERFAMILY SSF53474 6 346 2.01E-65 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 23 274 2.5E-59 T 09-03-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 SUPERFAMILY SSF49785 382 538 1.38E-55 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 SUPERFAMILY SSF49785 293 349 1.38E-55 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 316 530 1.5E-51 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS23410 1e6c553ab7d3a956505ce3eb93458319 682 Gene3D G3DSA:2.60.120.260 343 541 6.6E-58 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS29745 7dd82e4b10c56ae420250b98519239be 325 SUPERFAMILY SSF52540 2 222 1.38E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29745 7dd82e4b10c56ae420250b98519239be 325 SMART SM00382 26 204 4.4E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS29745 7dd82e4b10c56ae420250b98519239be 325 Gene3D G3DSA:3.40.50.300 2 222 2.6E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29745 7dd82e4b10c56ae420250b98519239be 325 Pfam PF00005 ABC transporter 18 155 1.6E-22 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 Gene3D G3DSA:3.30.70.370 303 341 6.2E-9 T 09-03-2017 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 Gene3D G3DSA:3.30.70.370 481 537 6.2E-9 T 09-03-2017 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 SUPERFAMILY SSF56672 163 559 1.89E-61 T 09-03-2017 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 Gene3D G3DSA:1.10.150.20 342 480 1.8E-16 T 09-03-2017 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 PRINTS PR00868 DNA-polymerase family A (pol I) signature 333 356 5.7E-5 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 PRINTS PR00868 DNA-polymerase family A (pol I) signature 502 515 5.7E-5 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 PRINTS PR00868 DNA-polymerase family A (pol I) signature 473 489 5.7E-5 T 09-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 Pfam PF00476 DNA polymerase family A 216 537 2.9E-28 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS11770 e9b62b466ff12b521fb68f541af7cea5 560 SMART SM00482 319 519 1.9E-11 T 09-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS12780 c724c884643f15dd26a4c35d69bd926e 283 SUPERFAMILY SSF55729 1 246 9.75E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS12780 c724c884643f15dd26a4c35d69bd926e 283 Pfam PF00583 Acetyltransferase (GNAT) family 49 122 1.4E-4 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS12780 c724c884643f15dd26a4c35d69bd926e 283 Gene3D G3DSA:3.40.630.30 2 119 4.9E-9 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS11345 f62f6797bbad976aef725f1e28dcb074 362 Gene3D G3DSA:1.10.620.20 30 337 2.8E-107 T 09-03-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 UA74_RS11345 f62f6797bbad976aef725f1e28dcb074 362 Pfam PF00268 Ribonucleotide reductase, small chain 42 329 1.8E-83 T 09-03-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11345 f62f6797bbad976aef725f1e28dcb074 362 PIRSF PIRSF000355 15 362 3.4E-127 T 09-03-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11345 f62f6797bbad976aef725f1e28dcb074 362 SUPERFAMILY SSF47240 26 333 5.8E-96 T 09-03-2017 IPR009078 Ferritin-like superfamily UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 SUPERFAMILY SSF51735 59 192 2.23E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 173 253 1.6E-17 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 Gene3D G3DSA:3.40.50.720 57 173 4.8E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 Gene3D G3DSA:3.30.360.10 174 250 4.7E-44 T 09-03-2017 UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 Gene3D G3DSA:3.30.360.10 315 450 4.7E-44 T 09-03-2017 UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 53 161 2.6E-18 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 SUPERFAMILY SSF55347 313 363 4.36E-23 T 09-03-2017 UA74_RS22205 ac17ac7fcfca84704a51bd0e14c60ba6 460 SUPERFAMILY SSF55347 169 251 4.36E-23 T 09-03-2017 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 20 666 1.6E-247 T 09-03-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Pfam PF13368 Topoisomerase C-terminal repeat 645 702 1.4E-7 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Pfam PF13368 Topoisomerase C-terminal repeat 771 824 4.0E-17 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Pfam PF13368 Topoisomerase C-terminal repeat 709 766 1.5E-13 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Pfam PF13368 Topoisomerase C-terminal repeat 839 892 6.7E-21 T 09-03-2017 IPR025589 Topoisomerase C-terminal repeat UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 SMART SM00436 132 220 1.7E-43 T 09-03-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 SUPERFAMILY SSF56712 18 602 9.42E-176 T 09-03-2017 IPR023405 DNA topoisomerase, type IA, core domain UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Pfam PF01131 DNA topoisomerase 156 597 5.5E-119 T 09-03-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Gene3D G3DSA:3.40.50.140 18 162 4.0E-47 T 09-03-2017 IPR006171 Toprim domain UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 SMART SM00493 18 132 2.2E-39 T 09-03-2017 IPR006171 Toprim domain UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Gene3D G3DSA:1.10.460.10 163 210 3.0E-49 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Gene3D G3DSA:1.10.460.10 508 602 3.0E-49 T 09-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 328 342 - T 09-03-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Hamap MF_00952 DNA topoisomerase 1 [topA]. 18 783 53.835 T 09-03-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 SMART SM00437 291 561 3.1E-124 T 09-03-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Pfam PF01751 Toprim domain 20 141 1.8E-28 T 09-03-2017 IPR006171 Toprim domain UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Gene3D G3DSA:2.70.20.10 360 507 1.2E-29 T 09-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 Gene3D G3DSA:2.70.20.10 213 355 7.8E-27 T 09-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 3.7E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 524 538 3.7E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 412 428 3.7E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 333 342 3.7E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 UA74_RS01410 80cf800fa65a5e47f55ac30b40c83584 921 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 3.7E-35 T 09-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 UA74_RS14760 ad3b78853607f9ac87ad839db75a29ac 250 Gene3D G3DSA:3.40.50.150 38 249 1.0E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14760 ad3b78853607f9ac87ad839db75a29ac 250 SUPERFAMILY SSF53335 28 249 4.22E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14760 ad3b78853607f9ac87ad839db75a29ac 250 Pfam PF08241 Methyltransferase domain 53 139 3.7E-9 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 Gene3D G3DSA:2.70.150.10 68 216 1.7E-19 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00941 Cadmium-transporting ATPase signature 120 136 3.2E-6 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00941 Cadmium-transporting ATPase signature 200 214 3.2E-6 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00941 Cadmium-transporting ATPase signature 181 197 3.2E-6 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00941 Cadmium-transporting ATPase signature 100 120 3.2E-6 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 Gene3D G3DSA:3.40.1110.10 333 430 2.8E-14 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 65 608 3.6E-148 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 583 4.0E-75 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 SUPERFAMILY SSF56784 312 332 3.69E-47 T 09-03-2017 IPR023214 HAD-like domain UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 SUPERFAMILY SSF56784 381 604 3.69E-47 T 09-03-2017 IPR023214 HAD-like domain UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 SUPERFAMILY SSF81653 118 215 5.49E-21 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 Gene3D G3DSA:3.40.50.1000 431 575 1.2E-38 T 09-03-2017 IPR023214 HAD-like domain UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 Pfam PF00702 haloacid dehalogenase-like hydrolase 310 518 1.7E-40 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 316 322 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 Gene3D G3DSA:3.40.1110.10 304 332 3.7E-6 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 Pfam PF00122 E1-E2 ATPase 86 305 1.6E-54 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 66 606 2.0E-167 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 SUPERFAMILY SSF81665 216 308 8.5E-13 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 SUPERFAMILY SSF81665 68 119 8.5E-13 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 314 328 3.6E-26 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 462 3.6E-26 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 430 441 3.6E-26 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 540 3.6E-26 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 3.6E-26 T 09-03-2017 UA74_RS16955 810213e65a354d15fab72c97ab5c5bbd 618 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 504 523 3.6E-26 T 09-03-2017 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 Gene3D G3DSA:2.40.50.140 17 155 3.5E-43 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 18 502 1.7E-135 T 09-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 Pfam PF01336 OB-fold nucleic acid binding domain 70 146 1.5E-9 T 09-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 SUPERFAMILY SSF50249 16 155 6.12E-34 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 7.6E-30 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 7.6E-30 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 7.6E-30 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 7.6E-30 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 7.6E-30 T 09-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 22 503 35.336 T 09-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 SUPERFAMILY SSF55681 162 501 5.77E-101 T 09-03-2017 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 Gene3D G3DSA:3.30.930.10 158 498 6.4E-103 T 09-03-2017 UA74_RS01580 5e8b1a0d9ca3d1da02b2164f28026001 503 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 500 8.2E-70 T 09-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 SMART SM00382 24 200 0.0037 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 Gene3D G3DSA:3.40.50.300 24 130 6.0E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 SUPERFAMILY SSF52540 4 241 2.86E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 SUPERFAMILY SSF46894 853 913 2.82E-15 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 891 903 2.1E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 891 2.1E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 861 875 2.1E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 Pfam PF00196 Bacterial regulatory proteins, luxR family 860 911 5.8E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 Gene3D G3DSA:3.30.750.24 131 169 9.5E-4 T 09-03-2017 IPR002645 STAS domain UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 SMART SM00421 858 915 2.2E-20 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 Gene3D G3DSA:1.25.40.10 570 809 1.9E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 Gene3D G3DSA:1.10.10.10 858 911 1.5E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 ProSitePatterns PS00622 LuxR-type HTH domain signature. 875 902 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05890 14921dc6ed78654f458566a4157673aa 921 Pfam PF13191 AAA ATPase domain 7 168 2.0E-18 T 09-03-2017 UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 20 757 1.9E-247 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Pfam PF02769 AIR synthase related protein, C-terminal domain 596 733 1.0E-16 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Pfam PF02769 AIR synthase related protein, C-terminal domain 208 363 7.7E-32 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 SUPERFAMILY SSF56042 207 448 4.64E-50 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 SUPERFAMILY SSF56042 595 760 2.84E-35 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 SUPERFAMILY SSF55326 16 198 7.48E-49 T 09-03-2017 UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Pfam PF00586 AIR synthase related protein, N-terminal domain 93 194 3.7E-22 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Pfam PF00586 AIR synthase related protein, N-terminal domain 463 581 2.0E-24 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 761 305.833 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 PIRSF PIRSF001587 4 761 3.8E-279 T 09-03-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Gene3D G3DSA:3.30.1330.10 51 199 7.1E-49 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Gene3D G3DSA:3.30.1330.10 436 585 4.6E-56 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 Gene3D G3DSA:3.90.650.10 263 364 2.6E-4 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29425 1df1a2f98c6cc4b5eb864196fc451a42 761 SUPERFAMILY SSF55326 419 588 2.49E-57 T 09-03-2017 UA74_RS15310 ca15c5ff4d60ab353bca3a0b5478151c 496 Gene3D G3DSA:3.40.50.1820 2 487 4.7E-108 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15310 ca15c5ff4d60ab353bca3a0b5478151c 496 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 166 181 - T 09-03-2017 IPR019826 Carboxylesterase type B, active site UA74_RS15310 ca15c5ff4d60ab353bca3a0b5478151c 496 SUPERFAMILY SSF53474 4 488 4.47E-96 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15310 ca15c5ff4d60ab353bca3a0b5478151c 496 Pfam PF00135 Carboxylesterase family 4 451 3.5E-76 T 09-03-2017 IPR002018 Carboxylesterase, type B UA74_RS17970 6db3a9b44c76b5d08feac7b0745b219d 321 SUPERFAMILY SSF48403 19 107 1.71E-13 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS17970 6db3a9b44c76b5d08feac7b0745b219d 321 SMART SM00248 38 67 0.55 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS17970 6db3a9b44c76b5d08feac7b0745b219d 321 SMART SM00248 70 101 24.0 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS17970 6db3a9b44c76b5d08feac7b0745b219d 321 Pfam PF12796 Ankyrin repeats (3 copies) 28 98 1.7E-8 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS17970 6db3a9b44c76b5d08feac7b0745b219d 321 Gene3D G3DSA:1.25.40.20 18 108 1.4E-14 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS05295 839e9085c7960f359b73272ade6ba9b5 353 SUPERFAMILY SSF54631 208 332 9.22E-20 T 09-03-2017 UA74_RS05295 839e9085c7960f359b73272ade6ba9b5 353 SMART SM00116 285 332 5.9E-5 T 09-03-2017 IPR000644 CBS domain UA74_RS05295 839e9085c7960f359b73272ade6ba9b5 353 Gene3D G3DSA:3.10.580.10 208 331 1.7E-13 T 09-03-2017 UA74_RS05295 839e9085c7960f359b73272ade6ba9b5 353 Pfam PF01595 Domain of unknown function DUF21 10 200 1.2E-33 T 09-03-2017 IPR002550 Domain of unknown function DUF21 UA74_RS05295 839e9085c7960f359b73272ade6ba9b5 353 Pfam PF00571 CBS domain 283 332 5.1E-7 T 09-03-2017 IPR000644 CBS domain UA74_RS02890 031895a45206c70509877948bc193392 201 SUPERFAMILY SSF46894 131 201 1.12E-17 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS02890 031895a45206c70509877948bc193392 201 SMART SM00448 2 115 4.6E-22 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS02890 031895a45206c70509877948bc193392 201 SUPERFAMILY SSF52172 1 129 7.83E-30 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS02890 031895a45206c70509877948bc193392 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.2E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS02890 031895a45206c70509877948bc193392 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.2E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS02890 031895a45206c70509877948bc193392 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.2E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS02890 031895a45206c70509877948bc193392 201 Pfam PF00072 Response regulator receiver domain 4 116 9.9E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS02890 031895a45206c70509877948bc193392 201 Gene3D G3DSA:1.10.10.10 121 201 2.7E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02890 031895a45206c70509877948bc193392 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 7.7E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS02890 031895a45206c70509877948bc193392 201 Gene3D G3DSA:3.40.50.2300 1 120 2.4E-31 T 09-03-2017 UA74_RS02890 031895a45206c70509877948bc193392 201 SMART SM00421 138 195 2.4E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS14045 71ab9b4803e8515eba34d62ff8288a47 593 PIRSF PIRSF002741 1 540 7.2E-93 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS14045 71ab9b4803e8515eba34d62ff8288a47 593 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 443 4.4E-87 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS14045 71ab9b4803e8515eba34d62ff8288a47 593 Gene3D G3DSA:3.40.190.10 187 301 1.3E-31 T 09-03-2017 UA74_RS14045 71ab9b4803e8515eba34d62ff8288a47 593 Gene3D G3DSA:3.90.76.10 37 186 8.7E-39 T 09-03-2017 UA74_RS14045 71ab9b4803e8515eba34d62ff8288a47 593 SUPERFAMILY SSF53850 23 534 6.92E-125 T 09-03-2017 UA74_RS14045 71ab9b4803e8515eba34d62ff8288a47 593 Gene3D G3DSA:3.10.105.10 302 509 2.5E-49 T 09-03-2017 UA74_RS10455 f82a15ebc075a42833691a44e25e4d70 316 Pfam PF00534 Glycosyl transferases group 1 210 291 5.0E-7 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS10455 f82a15ebc075a42833691a44e25e4d70 316 Gene3D G3DSA:3.40.50.2000 198 247 9.1E-5 T 09-03-2017 UA74_RS10455 f82a15ebc075a42833691a44e25e4d70 316 SUPERFAMILY SSF53756 49 313 2.3E-14 T 09-03-2017 UA74_RS00440 ce2a17b191c4fc9dc94c7347cf3c5b99 147 Pfam PF14534 Domain of unknown function (DUF4440) 25 136 3.1E-10 T 09-03-2017 IPR027843 Domain of unknown function DUF4440 UA74_RS00440 ce2a17b191c4fc9dc94c7347cf3c5b99 147 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 21 146 2.1E-19 T 09-03-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_RS00440 ce2a17b191c4fc9dc94c7347cf3c5b99 147 SUPERFAMILY SSF54427 20 146 3.39E-31 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS00440 ce2a17b191c4fc9dc94c7347cf3c5b99 147 Gene3D G3DSA:3.10.450.50 13 145 4.7E-34 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 SUPERFAMILY SSF52540 106 333 5.83E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 Gene3D G3DSA:3.40.50.300 113 298 4.4E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 Pfam PF00176 SNF2 family N-terminal domain 132 311 8.6E-8 T 09-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 Gene3D G3DSA:3.40.50.300 488 617 5.9E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 Pfam PF00271 Helicase conserved C-terminal domain 508 615 6.4E-16 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 SMART SM00487 108 328 2.6E-14 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 SUPERFAMILY SSF52540 243 313 4.16E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 SUPERFAMILY SSF52540 482 629 4.16E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20650 eeaafbed9062beb53fd8c5787d0db04f 1048 SMART SM00490 526 615 1.5E-15 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS02200 a34e6c712ebccec4471938717c2abf32 438 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 14 424 51.171 T 09-03-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_RS02200 a34e6c712ebccec4471938717c2abf32 438 Pfam PF13439 Glycosyltransferase Family 4 34 214 1.0E-28 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS02200 a34e6c712ebccec4471938717c2abf32 438 Gene3D G3DSA:3.40.50.2000 196 396 3.3E-40 T 09-03-2017 UA74_RS02200 a34e6c712ebccec4471938717c2abf32 438 Pfam PF00534 Glycosyl transferases group 1 224 393 2.3E-33 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS02200 a34e6c712ebccec4471938717c2abf32 438 SUPERFAMILY SSF53756 33 420 2.62E-82 T 09-03-2017 UA74_RS02200 a34e6c712ebccec4471938717c2abf32 438 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 15 420 2.0E-187 T 09-03-2017 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_RS24095 bb0371b4ae02dbfc1fdfcdd8d0542d3e 309 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 1 307 32.816 T 09-03-2017 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 UA74_RS24095 bb0371b4ae02dbfc1fdfcdd8d0542d3e 309 Pfam PF01180 Dihydroorotate dehydrogenase 7 289 6.0E-52 T 09-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UA74_RS24095 bb0371b4ae02dbfc1fdfcdd8d0542d3e 309 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 244 264 - T 09-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UA74_RS24095 bb0371b4ae02dbfc1fdfcdd8d0542d3e 309 Gene3D G3DSA:3.20.20.70 1 295 2.3E-73 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS24095 bb0371b4ae02dbfc1fdfcdd8d0542d3e 309 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 303 1.5E-81 T 09-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UA74_RS24095 bb0371b4ae02dbfc1fdfcdd8d0542d3e 309 PIRSF PIRSF000164 1 306 3.0E-63 T 09-03-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 UA74_RS24095 bb0371b4ae02dbfc1fdfcdd8d0542d3e 309 SUPERFAMILY SSF51395 2 303 3.3E-66 T 09-03-2017 UA74_RS03560 a49019f584d08b5f958a1dc5a6e44c0a 280 PIRSF PIRSF002854 1 280 2.4E-92 T 09-03-2017 IPR004872 Lipoprotein NlpA family UA74_RS03560 a49019f584d08b5f958a1dc5a6e44c0a 280 Gene3D G3DSA:3.40.190.10 42 171 1.8E-45 T 09-03-2017 UA74_RS03560 a49019f584d08b5f958a1dc5a6e44c0a 280 SUPERFAMILY SSF53850 43 280 3.43E-71 T 09-03-2017 UA74_RS03560 a49019f584d08b5f958a1dc5a6e44c0a 280 Pfam PF03180 NLPA lipoprotein 43 279 6.2E-78 T 09-03-2017 IPR004872 Lipoprotein NlpA family UA74_RS19515 da6a0d569abbb6960ce45931df5353f6 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 69 7.1E-10 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS19515 da6a0d569abbb6960ce45931df5353f6 96 SUPERFAMILY SSF54909 1 69 2.64E-14 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS19515 da6a0d569abbb6960ce45931df5353f6 96 Gene3D G3DSA:3.30.70.900 1 69 5.9E-13 T 09-03-2017 UA74_RS20130 b176a7daf4d633a8a01e411045b88088 334 Gene3D G3DSA:3.40.50.1820 22 323 5.6E-70 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20130 b176a7daf4d633a8a01e411045b88088 334 SUPERFAMILY SSF53474 27 324 4.12E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20130 b176a7daf4d633a8a01e411045b88088 334 Pfam PF05448 Acetyl xylan esterase (AXE1) 28 319 1.1E-63 T 09-03-2017 IPR008391 Acetyl xylan esterase UA74_RS24280 0bc48c26d991fcfecf6f41795efbeb64 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 305 1.5E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24280 0bc48c26d991fcfecf6f41795efbeb64 310 SUPERFAMILY SSF161098 78 299 4.84E-52 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24280 0bc48c26d991fcfecf6f41795efbeb64 310 Gene3D G3DSA:1.10.3720.10 84 308 7.8E-55 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS16780 4265d4c8205ff04c8adf087c4de11642 354 Pfam PF12833 Helix-turn-helix domain 264 341 3.4E-17 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS16780 4265d4c8205ff04c8adf087c4de11642 354 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 33 214 2.4E-37 T 09-03-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal UA74_RS16780 4265d4c8205ff04c8adf087c4de11642 354 SMART SM00342 257 339 9.8E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS16780 4265d4c8205ff04c8adf087c4de11642 354 SUPERFAMILY SSF46689 292 342 1.48E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS16780 4265d4c8205ff04c8adf087c4de11642 354 Gene3D G3DSA:1.10.10.60 291 344 2.1E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 235 252 3.0E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 332 341 3.0E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 341 352 3.0E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 276 287 3.0E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 Gene3D G3DSA:1.10.630.10 9 374 1.4E-62 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 SUPERFAMILY SSF48264 25 372 4.45E-53 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 143 159 7.6E-15 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 341 352 7.6E-15 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 160 175 7.6E-15 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 96 107 7.6E-15 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 272 283 7.6E-15 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS04345 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 332 341 7.6E-15 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09975 c99bd3c8ccaeed59a722b3765eb42c80 376 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 09-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 UA74_RS09975 c99bd3c8ccaeed59a722b3765eb42c80 376 Gene3D G3DSA:3.90.1150.10 265 368 6.1E-30 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS09975 c99bd3c8ccaeed59a722b3765eb42c80 376 SUPERFAMILY SSF53383 37 366 1.67E-69 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS09975 c99bd3c8ccaeed59a722b3765eb42c80 376 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 18 370 52.805 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_RS09975 c99bd3c8ccaeed59a722b3765eb42c80 376 Pfam PF00155 Aminotransferase class I and II 38 363 1.4E-51 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS09975 c99bd3c8ccaeed59a722b3765eb42c80 376 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 20 368 2.6E-94 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_RS09975 c99bd3c8ccaeed59a722b3765eb42c80 376 Gene3D G3DSA:3.40.640.10 67 264 1.9E-48 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 PRINTS PR00400 Tetracycline repressor protein signature 113 136 1.1E-6 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 PRINTS PR00400 Tetracycline repressor protein signature 287 301 1.1E-6 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 SUPERFAMILY SSF46689 89 154 5.99E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 Gene3D G3DSA:1.10.10.10 13 82 3.6E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 Gene3D G3DSA:1.10.357.10 88 306 2.0E-50 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 SUPERFAMILY SSF46785 8 88 1.77E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 Pfam PF00440 Bacterial regulatory proteins, tetR family 101 145 8.9E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 SMART SM00345 16 75 1.2E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 4.4E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 SUPERFAMILY SSF48498 269 306 1.11E-18 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 SUPERFAMILY SSF48498 163 238 1.11E-18 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS18630 80c7e02339d40f40492b4e8d9a4e71fd 307 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 157 303 1.9E-15 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS23860 7149efb9274f11863b68566f6436df5e 319 Gene3D G3DSA:3.20.20.70 9 306 5.4E-63 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS23860 7149efb9274f11863b68566f6436df5e 319 PIRSF PIRSF001365 9 311 2.6E-47 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS23860 7149efb9274f11863b68566f6436df5e 319 Pfam PF00701 Dihydrodipicolinate synthetase family 12 304 2.2E-46 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS23860 7149efb9274f11863b68566f6436df5e 319 SUPERFAMILY SSF51569 10 305 7.75E-56 T 09-03-2017 UA74_RS23860 7149efb9274f11863b68566f6436df5e 319 SMART SM01130 11 307 4.8E-61 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS28625 af833869d60bff0ee8660aa02ea50c8a 208 Pfam PF05331 Protein of unknown function (DUF742) 97 208 2.6E-32 T 09-03-2017 IPR007995 Protein of unknown function DUF742 UA74_RS03260 beef9855ecdfa2a27605a522a272370c 220 Gene3D G3DSA:3.40.50.10420 22 204 4.9E-43 T 09-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain UA74_RS03260 beef9855ecdfa2a27605a522a272370c 220 SUPERFAMILY SSF100950 22 207 1.95E-36 T 09-03-2017 UA74_RS03260 beef9855ecdfa2a27605a522a272370c 220 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 23 202 1.2E-36 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase UA74_RS03260 beef9855ecdfa2a27605a522a272370c 220 PIRSF PIRSF006806 19 205 3.2E-31 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase UA74_RS03260 beef9855ecdfa2a27605a522a272370c 220 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 23 202 3.1E-31 T 09-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase UA74_RS14285 6e7726065bdda256c80b48e2950eb0d5 239 Gene3D G3DSA:1.10.10.10 8 90 4.5E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14285 6e7726065bdda256c80b48e2950eb0d5 239 SUPERFAMILY SSF46785 7 91 6.57E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14285 6e7726065bdda256c80b48e2950eb0d5 239 Pfam PF12840 Helix-turn-helix domain 12 71 7.4E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14285 6e7726065bdda256c80b48e2950eb0d5 239 SMART SM00418 14 91 5.6E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS12375 11851427e0a7f2d3cf71cc07212e1c7e 193 Gene3D G3DSA:1.10.10.10 125 188 3.5E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12375 11851427e0a7f2d3cf71cc07212e1c7e 193 Pfam PF04542 Sigma-70 region 2 31 99 1.0E-13 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS12375 11851427e0a7f2d3cf71cc07212e1c7e 193 Pfam PF08281 Sigma-70, region 4 132 184 9.7E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS12375 11851427e0a7f2d3cf71cc07212e1c7e 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 186 1.2E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS12375 11851427e0a7f2d3cf71cc07212e1c7e 193 Gene3D G3DSA:1.10.1740.10 10 119 2.1E-24 T 09-03-2017 UA74_RS12375 11851427e0a7f2d3cf71cc07212e1c7e 193 SUPERFAMILY SSF88659 125 188 4.36E-12 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS12375 11851427e0a7f2d3cf71cc07212e1c7e 193 SUPERFAMILY SSF88946 10 106 2.35E-21 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS01105 48b45853dc32cf0a5f7b3d3128aaea3d 163 Gene3D G3DSA:1.20.1260.10 14 159 4.1E-40 T 09-03-2017 IPR012347 Ferritin-related UA74_RS01105 48b45853dc32cf0a5f7b3d3128aaea3d 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 139 157 2.4E-11 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 UA74_RS01105 48b45853dc32cf0a5f7b3d3128aaea3d 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 44 60 2.4E-11 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 UA74_RS01105 48b45853dc32cf0a5f7b3d3128aaea3d 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 68 84 2.4E-11 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 UA74_RS01105 48b45853dc32cf0a5f7b3d3128aaea3d 163 Pfam PF00210 Ferritin-like domain 25 162 2.7E-20 T 09-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 UA74_RS01105 48b45853dc32cf0a5f7b3d3128aaea3d 163 SUPERFAMILY SSF47240 11 159 1.89E-40 T 09-03-2017 IPR009078 Ferritin-like superfamily UA74_RS01105 48b45853dc32cf0a5f7b3d3128aaea3d 163 PIRSF PIRSF005900 1 163 1.1E-40 T 09-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 UA74_RS12730 3391d7a1a4740872c0009ba4885b2b6e 134 Pfam PF01638 HxlR-like helix-turn-helix 32 114 2.4E-26 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS12730 3391d7a1a4740872c0009ba4885b2b6e 134 Gene3D G3DSA:1.10.10.10 15 129 1.0E-38 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12730 3391d7a1a4740872c0009ba4885b2b6e 134 SUPERFAMILY SSF46785 18 128 7.96E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28230 b252947da6430db7af4bc2b24e9aa753 105 Gene3D G3DSA:1.10.287.1060 2 100 2.2E-19 T 09-03-2017 UA74_RS28230 b252947da6430db7af4bc2b24e9aa753 105 SUPERFAMILY SSF140453 7 98 7.06E-17 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS28230 b252947da6430db7af4bc2b24e9aa753 105 Pfam PF06013 Proteins of 100 residues with WXG 7 88 2.3E-13 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS28230 b252947da6430db7af4bc2b24e9aa753 105 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 92 1.3E-16 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS07820 0b722704e65963be11d91e4d49068a0b 278 PIRSF PIRSF006648 8 278 5.8E-64 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS07820 0b722704e65963be11d91e4d49068a0b 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 201 220 9.3E-9 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS07820 0b722704e65963be11d91e4d49068a0b 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 127 152 9.3E-9 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS07820 0b722704e65963be11d91e4d49068a0b 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 221 240 9.3E-9 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS07820 0b722704e65963be11d91e4d49068a0b 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 47 68 9.3E-9 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS07820 0b722704e65963be11d91e4d49068a0b 278 Pfam PF01061 ABC-2 type transporter 28 242 3.1E-33 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS13940 5775101483aa8f24d39c3f7c61645573 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13940 5775101483aa8f24d39c3f7c61645573 134 Gene3D G3DSA:1.10.1660.10 3 118 3.1E-30 T 09-03-2017 UA74_RS13940 5775101483aa8f24d39c3f7c61645573 134 SUPERFAMILY SSF46955 3 115 1.9E-25 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS13940 5775101483aa8f24d39c3f7c61645573 134 SMART SM00422 1 69 4.8E-19 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS13940 5775101483aa8f24d39c3f7c61645573 134 Pfam PF13411 MerR HTH family regulatory protein 3 63 4.1E-18 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS05435 f3c55bbfb6fc68c9a4c8e06cb6ac6a3f 296 Gene3D G3DSA:3.40.50.720 3 240 8.0E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05435 f3c55bbfb6fc68c9a4c8e06cb6ac6a3f 296 SUPERFAMILY SSF51735 5 291 1.23E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05435 f3c55bbfb6fc68c9a4c8e06cb6ac6a3f 296 Pfam PF05368 NmrA-like family 7 243 4.5E-41 T 09-03-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 Gene3D G3DSA:3.40.50.2300 2 150 9.0E-25 T 09-03-2017 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 Gene3D G3DSA:1.10.10.10 151 211 2.7E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 SMART SM00448 1 120 2.3E-9 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 SMART SM00421 146 208 1.5E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 SUPERFAMILY SSF52172 2 171 1.19E-15 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 Pfam PF00072 Response regulator receiver domain 6 108 4.5E-12 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 193 3.5E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.1E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.1E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03160 b4bbd9b1a3cd9bc0205ed996a906b61c 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.1E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 149 164 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 314 329 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 335 344 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 132 148 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 286 313 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 344 355 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 268 279 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 85 96 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00359 B-class P450 signature 187 209 9.4E-56 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 Pfam PF00067 Cytochrome P450 189 365 1.2E-26 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 Gene3D G3DSA:1.10.630.10 8 395 1.2E-120 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 SUPERFAMILY SSF48264 19 395 2.1E-92 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00385 P450 superfamily signature 233 250 6.6E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00385 P450 superfamily signature 268 279 6.6E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00385 P450 superfamily signature 335 344 6.6E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS08340 74b7ec5db2c0f6b6b5ed4cc8e650abb7 395 PRINTS PR00385 P450 superfamily signature 344 355 6.6E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 SUPERFAMILY SSF51556 66 359 2.98E-94 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 Gene3D G3DSA:2.30.40.10 14 67 7.5E-12 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 PIRSF PIRSF038994 15 390 3.4E-116 T 09-03-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 Gene3D G3DSA:2.30.40.10 339 388 7.4E-12 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 Pfam PF01979 Amidohydrolase family 62 387 3.0E-28 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 Gene3D G3DSA:3.20.20.140 68 338 2.7E-101 T 09-03-2017 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 SUPERFAMILY SSF51338 6 66 2.43E-17 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 SUPERFAMILY SSF51338 359 387 2.43E-17 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS29670 ab67fee435751e787306ada22f5953a0 390 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 16 382 2.4E-84 T 09-03-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 UA74_RS06580 8ca1de0bbc5330c88650a45720b3a516 193 Gene3D G3DSA:3.40.1410.10 10 162 4.5E-16 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS06580 8ca1de0bbc5330c88650a45720b3a516 193 SUPERFAMILY SSF64288 10 162 6.73E-19 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 3.7E-20 T 09-03-2017 IPR022687 DTXR-type HTH domain GO:0003677 UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 Gene3D G3DSA:2.30.30.90 134 228 3.5E-24 T 09-03-2017 UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 Gene3D G3DSA:1.10.60.10 75 133 2.0E-30 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 Gene3D G3DSA:1.10.10.10 3 73 5.2E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 SUPERFAMILY SSF46785 2 62 3.75E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 Pfam PF04023 FeoA domain 162 229 6.6E-5 T 09-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 SUPERFAMILY SSF50037 130 228 5.26E-20 T 09-03-2017 IPR008988 Transcriptional repressor, C-terminal UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 SMART SM00529 26 125 1.8E-41 T 09-03-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 SUPERFAMILY SSF47979 65 137 1.44E-25 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 UA74_RS08830 5e28847bd03ab14c49d076715160641a 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.6E-28 T 09-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 UA74_RS00245 beca3a51851f3831f766665b8b4d5224 377 SUPERFAMILY SSF52540 1 240 4.76E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00245 beca3a51851f3831f766665b8b4d5224 377 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS00245 beca3a51851f3831f766665b8b4d5224 377 Gene3D G3DSA:3.40.50.300 1 237 7.9E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00245 beca3a51851f3831f766665b8b4d5224 377 Pfam PF00005 ABC transporter 19 164 6.1E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00245 beca3a51851f3831f766665b8b4d5224 377 SUPERFAMILY SSF54631 250 364 1.39E-5 T 09-03-2017 UA74_RS00245 beca3a51851f3831f766665b8b4d5224 377 SMART SM00382 27 223 3.1E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS23035 efed824d723cd9cb2822a211db18914f 339 SUPERFAMILY SSF51430 26 337 1.31E-52 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS23035 efed824d723cd9cb2822a211db18914f 339 Gene3D G3DSA:3.20.20.100 26 337 2.8E-57 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS23035 efed824d723cd9cb2822a211db18914f 339 Pfam PF00248 Aldo/keto reductase family 25 336 7.5E-39 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 Pfam PF01494 FAD binding domain 8 366 1.4E-93 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 SUPERFAMILY SSF51905 8 189 6.65E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 SUPERFAMILY SSF51905 290 380 6.65E-58 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 7.4E-40 T 09-03-2017 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 354 7.4E-40 T 09-03-2017 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 318 7.4E-40 T 09-03-2017 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 7.4E-40 T 09-03-2017 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 354 370 7.4E-40 T 09-03-2017 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 7.4E-40 T 09-03-2017 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 Gene3D G3DSA:3.50.50.60 7 73 1.3E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 Gene3D G3DSA:3.50.50.60 110 194 1.3E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11000 9f381b6d767ff159a5de6f8992aa5a76 532 Gene3D G3DSA:3.50.50.60 291 369 1.3E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS14830 8d526d1524d36a56d34756d77ae557d2 462 Pfam PF11700 Vacuole effluxer Atg22 like 14 454 3.9E-94 T 09-03-2017 IPR024671 Autophagy-related protein 22-like UA74_RS14830 8d526d1524d36a56d34756d77ae557d2 462 Gene3D G3DSA:1.20.1250.20 32 230 1.3E-14 T 09-03-2017 UA74_RS14830 8d526d1524d36a56d34756d77ae557d2 462 Gene3D G3DSA:1.20.1250.20 265 448 6.0E-16 T 09-03-2017 UA74_RS14830 8d526d1524d36a56d34756d77ae557d2 462 SUPERFAMILY SSF103473 19 449 4.19E-40 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS03155 f2ce62c7a0bfcecc15b5ebb702892be6 557 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 546 2.4E-156 T 09-03-2017 IPR010281 Protein of unknown function DUF885 UA74_RS18715 66f1dd5b13c8f8a515564d58f1e713a8 145 SUPERFAMILY SSF46785 5 143 4.95E-39 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18715 66f1dd5b13c8f8a515564d58f1e713a8 145 Pfam PF01638 HxlR-like helix-turn-helix 18 105 6.7E-24 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS18715 66f1dd5b13c8f8a515564d58f1e713a8 145 Gene3D G3DSA:1.10.10.10 5 107 3.7E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 SUPERFAMILY SSF49899 623 818 5.7E-33 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 Gene3D G3DSA:2.60.120.200 650 818 2.2E-32 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 SUPERFAMILY SSF51445 307 594 6.1E-57 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 SUPERFAMILY SSF49303 217 311 1.32E-11 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 Gene3D G3DSA:2.60.120.260 42 205 3.7E-51 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 SMART SM00560 679 811 7.3E-21 T 09-03-2017 IPR006558 LamG-like jellyroll fold UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 Pfam PF00703 Glycosyl hydrolases family 2 249 310 6.3E-9 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 663 814 3.7E-27 T 09-03-2017 UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 Gene3D G3DSA:2.60.40.320 206 311 4.0E-17 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 88 208 5.6E-11 T 09-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 SUPERFAMILY SSF49785 42 214 3.04E-44 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS18390 0bfa8ad9de2f75140b9c89858910d1de 822 Gene3D G3DSA:3.20.20.80 323 595 1.7E-44 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07760 0d2489b4d8963df1285a7fee9c35e13a 302 Gene3D G3DSA:3.40.50.300 1 216 2.3E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07760 0d2489b4d8963df1285a7fee9c35e13a 302 Pfam PF00005 ABC transporter 17 154 1.1E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS07760 0d2489b4d8963df1285a7fee9c35e13a 302 SUPERFAMILY SSF52540 1 215 6.45E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07760 0d2489b4d8963df1285a7fee9c35e13a 302 SMART SM00382 25 203 2.8E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 Pfam PF01595 Domain of unknown function DUF21 9 193 6.6E-42 T 09-03-2017 IPR002550 Domain of unknown function DUF21 UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 SMART SM00116 285 333 7.1 T 09-03-2017 IPR000644 CBS domain UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 SMART SM00116 222 271 0.3 T 09-03-2017 IPR000644 CBS domain UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 SMART SM01091 348 426 4.6E-21 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 SUPERFAMILY SSF54631 210 343 2.15E-28 T 09-03-2017 UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 Gene3D G3DSA:3.10.580.10 201 327 2.5E-15 T 09-03-2017 UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 Gene3D G3DSA:3.30.465.10 328 425 1.7E-24 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 Pfam PF00571 CBS domain 298 333 1.7E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 Pfam PF00571 CBS domain 218 270 2.1E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 SUPERFAMILY SSF56176 352 431 4.36E-19 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS26290 86d0bf99344b1eb0fcdc76d1b17924b2 455 Pfam PF03471 Transporter associated domain 351 425 6.9E-20 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS20495 2b1b367264e42579101053163095e9cf 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 09-03-2017 IPR019844 Cold-shock conserved site UA74_RS20495 2b1b367264e42579101053163095e9cf 66 SMART SM00357 3 66 6.9E-29 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 UA74_RS20495 2b1b367264e42579101053163095e9cf 66 PIRSF PIRSF002599 1 66 9.6E-24 T 09-03-2017 IPR012156 Cold shock, CspA GO:0003676 UA74_RS20495 2b1b367264e42579101053163095e9cf 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 7.6E-30 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS20495 2b1b367264e42579101053163095e9cf 66 Gene3D G3DSA:2.40.50.140 1 64 9.9E-32 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS20495 2b1b367264e42579101053163095e9cf 66 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS20495 2b1b367264e42579101053163095e9cf 66 PRINTS PR00050 Cold shock protein signature 39 57 1.1E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS20495 2b1b367264e42579101053163095e9cf 66 PRINTS PR00050 Cold shock protein signature 24 33 1.1E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS20495 2b1b367264e42579101053163095e9cf 66 SUPERFAMILY SSF50249 1 65 1.59E-24 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS29800 a69359ab33315fb87484a58be67ed6f7 189 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 189 23.861 T 09-03-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS29800 a69359ab33315fb87484a58be67ed6f7 189 Pfam PF00156 Phosphoribosyl transferase domain 72 168 1.1E-12 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_RS29800 a69359ab33315fb87484a58be67ed6f7 189 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 20 183 3.5E-33 T 09-03-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS29800 a69359ab33315fb87484a58be67ed6f7 189 SUPERFAMILY SSF53271 11 185 7.21E-34 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS29800 a69359ab33315fb87484a58be67ed6f7 189 Gene3D G3DSA:3.40.50.2020 12 186 4.6E-48 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 SUPERFAMILY SSF56655 8 267 2.36E-67 T 09-03-2017 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 Gene3D G3DSA:3.30.540.10 7 158 2.2E-42 T 09-03-2017 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 89 102 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 Pfam PF00459 Inositol monophosphatase family 8 236 1.5E-56 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 Gene3D G3DSA:3.40.190.80 159 268 3.5E-29 T 09-03-2017 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 138 161 1.6E-39 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 215 239 1.6E-39 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 1.6E-39 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 68 84 1.6E-39 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 46 66 1.6E-39 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 184 205 1.6E-39 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS08535 3a79045a0c70189a479c2ae8fec0a8a2 274 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 218 232 - T 09-03-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 Pfam PF00082 Subtilase family 176 393 1.0E-32 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 Pfam PF05922 Peptidase inhibitor I9 96 138 4.3E-6 T 09-03-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 PRINTS PR00723 Subtilisin serine protease family (S8) signature 169 188 2.1E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 PRINTS PR00723 Subtilisin serine protease family (S8) signature 360 376 2.1E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 PRINTS PR00723 Subtilisin serine protease family (S8) signature 207 220 2.1E-16 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 SUPERFAMILY SSF52743 141 400 4.32E-73 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 SUPERFAMILY SSF54897 68 138 1.98E-11 T 09-03-2017 IPR009020 Proteinase propeptide inhibitor UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 361 371 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 211 221 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 Gene3D G3DSA:3.40.50.200 143 407 5.6E-81 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 174 185 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_RS07240 1af66a7a63e61ab288310fcf66c4bf68 417 Gene3D G3DSA:3.30.70.80 62 142 3.7E-16 T 09-03-2017 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 UA74_RS25175 759a97ecb2e9ed3e51b8c795247a3b1c 249 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 249 42.041 T 09-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS25175 759a97ecb2e9ed3e51b8c795247a3b1c 249 Pfam PF02654 Cobalamin-5-phosphate synthase 8 243 3.8E-46 T 09-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS25175 759a97ecb2e9ed3e51b8c795247a3b1c 249 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 1 244 9.5E-34 T 09-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 Pfam PF00381 PTS HPr component phosphorylation site 197 275 2.4E-20 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 PRINTS PR00107 Phosphocarrier protein signature 247 264 7.6E-9 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 PRINTS PR00107 Phosphocarrier protein signature 232 247 7.6E-9 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 PRINTS PR00107 Phosphocarrier protein signature 207 223 7.6E-9 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 199 274 9.6E-20 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 Gene3D G3DSA:3.40.50.510 3 124 3.5E-41 T 09-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 207 214 - T 09-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 SUPERFAMILY SSF55594 198 279 6.67E-21 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 Pfam PF03610 PTS system fructose IIA component 5 116 1.4E-23 T 09-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 SUPERFAMILY SSF53062 4 122 3.4E-29 T 09-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 Gene3D G3DSA:3.30.1340.10 197 279 1.1E-22 T 09-03-2017 IPR000032 Phosphocarrier protein HPr-like UA74_RS07280 4ae141e9c891c90be703f47b6e9586ee 281 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 120 2.9E-35 T 09-03-2017 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain UA74_RS03755 3767d3d407757cac54f875f540af6d6d 522 Pfam PF13406 Transglycosylase SLT domain 225 274 1.1E-6 T 09-03-2017 IPR031304 Transglycosylase SLT domain 2 UA74_RS03755 3767d3d407757cac54f875f540af6d6d 522 Gene3D G3DSA:1.10.530.10 158 290 2.5E-7 T 09-03-2017 UA74_RS03755 3767d3d407757cac54f875f540af6d6d 522 SUPERFAMILY SSF53955 140 308 1.15E-37 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 12 417 9.3E-134 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 SUPERFAMILY SSF46589 1 112 3.19E-19 T 09-03-2017 IPR010978 tRNA-binding arm GO:0000166 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 PIRSF PIRSF001529 1 423 2.5E-141 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 224 400 6.4E-33 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 SUPERFAMILY SSF55681 122 423 4.68E-91 T 09-03-2017 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 36.725 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 Gene3D G3DSA:3.30.930.10 105 420 2.4E-124 T 09-03-2017 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 265 277 2.4E-26 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 277 290 2.4E-26 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 317 330 2.4E-26 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 352 368 2.4E-26 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 334 350 2.4E-26 T 09-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 Gene3D G3DSA:1.10.287.40 1 104 9.1E-17 T 09-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS11485 05ea48b3e6becd470b03c922579660d3 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 3.4E-18 T 09-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_RS00615 b646384528906384bae0d1ab0212016d 189 SUPERFAMILY SSF51182 56 183 5.24E-21 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS00615 b646384528906384bae0d1ab0212016d 189 Pfam PF07883 Cupin domain 116 183 1.4E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS00615 b646384528906384bae0d1ab0212016d 189 Gene3D G3DSA:2.60.120.10 67 184 1.1E-16 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS00615 b646384528906384bae0d1ab0212016d 189 SMART SM00530 16 71 9.1E-16 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS00615 b646384528906384bae0d1ab0212016d 189 Pfam PF13560 Helix-turn-helix domain 13 71 4.4E-16 T 09-03-2017 UA74_RS00615 b646384528906384bae0d1ab0212016d 189 SUPERFAMILY SSF47413 10 77 5.36E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS00615 b646384528906384bae0d1ab0212016d 189 Gene3D G3DSA:1.10.260.40 12 66 7.8E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 SUPERFAMILY SSF55781 198 344 6.32E-5 T 09-03-2017 IPR029016 GAF domain-like UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 SUPERFAMILY SSF55874 457 541 1.2E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 Gene3D G3DSA:3.30.450.40 186 333 5.1E-4 T 09-03-2017 IPR029016 GAF domain-like UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 SUPERFAMILY SSF55781 30 191 3.71E-16 T 09-03-2017 IPR029016 GAF domain-like UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 SMART SM00065 44 175 8.8E-4 T 09-03-2017 IPR003018 GAF domain GO:0005515 UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 Gene3D G3DSA:3.30.450.40 30 174 8.4E-12 T 09-03-2017 IPR029016 GAF domain-like UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 Pfam PF13185 GAF domain 43 165 1.7E-7 T 09-03-2017 IPR003018 GAF domain GO:0005515 UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 Pfam PF07730 Histidine kinase 350 411 1.0E-10 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS10585 8b6dc401beb53ed09bbb6acc1140a5bc 549 Gene3D G3DSA:3.30.565.10 426 505 2.9E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS15425 df3e462772f6b19fede872ddc13aa639 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 4.7E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15425 df3e462772f6b19fede872ddc13aa639 185 SUPERFAMILY SSF46689 3 69 1.08E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15425 df3e462772f6b19fede872ddc13aa639 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.4E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15425 df3e462772f6b19fede872ddc13aa639 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.4E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15425 df3e462772f6b19fede872ddc13aa639 185 SUPERFAMILY SSF48498 82 177 6.0E-19 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS15425 df3e462772f6b19fede872ddc13aa639 185 Gene3D G3DSA:1.10.357.10 2 176 4.0E-27 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS18035 89313fedba079b24aa7aecd50704b080 555 Pfam PF01593 Flavin containing amine oxidoreductase 30 405 8.1E-12 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS18035 89313fedba079b24aa7aecd50704b080 555 Gene3D G3DSA:3.50.50.60 19 124 1.8E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18035 89313fedba079b24aa7aecd50704b080 555 Gene3D G3DSA:3.50.50.60 233 306 1.8E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18035 89313fedba079b24aa7aecd50704b080 555 SUPERFAMILY SSF51905 486 522 2.75E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18035 89313fedba079b24aa7aecd50704b080 555 SUPERFAMILY SSF51905 18 349 2.75E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17935 48a806255ae1ad955147264b904a7b10 379 SUPERFAMILY SSF51679 1 333 3.4E-70 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS17935 48a806255ae1ad955147264b904a7b10 379 Pfam PF00296 Luciferase-like monooxygenase 1 293 6.3E-55 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS17935 48a806255ae1ad955147264b904a7b10 379 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 4.7E-214 T 09-03-2017 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative UA74_RS17935 48a806255ae1ad955147264b904a7b10 379 Gene3D G3DSA:3.20.20.30 1 335 1.6E-77 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS00925 7d20317d5d89e7dc8de54c1d14a651c1 282 Gene3D G3DSA:3.40.50.300 5 250 4.5E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00925 7d20317d5d89e7dc8de54c1d14a651c1 282 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS00925 7d20317d5d89e7dc8de54c1d14a651c1 282 SMART SM00382 35 235 1.2E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00925 7d20317d5d89e7dc8de54c1d14a651c1 282 SUPERFAMILY SSF52540 6 248 1.02E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00925 7d20317d5d89e7dc8de54c1d14a651c1 282 Pfam PF00005 ABC transporter 27 178 2.5E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS02065 9e4fd6320431806a7aee5e5b270da39d 299 Gene3D G3DSA:3.60.60.10 16 191 2.6E-19 T 09-03-2017 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 UA74_RS02065 9e4fd6320431806a7aee5e5b270da39d 299 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 65 273 3.7E-14 T 09-03-2017 IPR005079 Peptidase C45 UA74_RS02065 9e4fd6320431806a7aee5e5b270da39d 299 SUPERFAMILY SSF56235 16 174 2.85E-12 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS18260 a621cffa0366054542a50aaf6bbc91be 371 SUPERFAMILY SSF52540 8 208 1.78E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18260 a621cffa0366054542a50aaf6bbc91be 371 Gene3D G3DSA:3.30.1220.10 244 350 1.1E-19 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS18260 a621cffa0366054542a50aaf6bbc91be 371 SMART SM00833 259 350 1.4E-16 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS18260 a621cffa0366054542a50aaf6bbc91be 371 SUPERFAMILY SSF90002 260 350 7.19E-18 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS18260 a621cffa0366054542a50aaf6bbc91be 371 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 260 350 3.6E-23 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS18260 a621cffa0366054542a50aaf6bbc91be 371 Gene3D G3DSA:3.40.50.300 8 199 1.7E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18260 a621cffa0366054542a50aaf6bbc91be 371 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 184 4.2E-43 T 09-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain UA74_RS26045 2502cd79f08f7a572aca555c5e4de1f6 233 SMART SM00346 7 92 1.5E-20 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS26045 2502cd79f08f7a572aca555c5e4de1f6 233 Pfam PF01614 Bacterial transcriptional regulator 124 229 2.5E-14 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS26045 2502cd79f08f7a572aca555c5e4de1f6 233 Gene3D G3DSA:1.10.10.10 5 66 1.2E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26045 2502cd79f08f7a572aca555c5e4de1f6 233 SUPERFAMILY SSF46785 7 74 6.95E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26045 2502cd79f08f7a572aca555c5e4de1f6 233 Pfam PF09339 IclR helix-turn-helix domain 10 56 1.9E-11 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS26045 2502cd79f08f7a572aca555c5e4de1f6 233 SUPERFAMILY SSF55781 63 233 2.49E-35 T 09-03-2017 IPR029016 GAF domain-like UA74_RS26045 2502cd79f08f7a572aca555c5e4de1f6 233 Gene3D G3DSA:3.30.450.40 73 233 4.2E-40 T 09-03-2017 IPR029016 GAF domain-like UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 Pfam PF14759 Reductase C-terminal 322 379 2.0E-10 T 09-03-2017 IPR028202 Reductase, C-terminal UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 303 1.2E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 Gene3D G3DSA:3.30.390.30 322 379 8.7E-16 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 Gene3D G3DSA:3.50.50.60 4 110 2.9E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 Gene3D G3DSA:3.50.50.60 111 312 7.4E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 2.8E-17 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.8E-17 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 2.8E-17 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 2.8E-17 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 SUPERFAMILY SSF51905 5 311 6.98E-37 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.3E-21 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 2.3E-21 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.3E-21 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.3E-21 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 2.3E-21 T 09-03-2017 UA74_RS17435 b9da33d16a6b1abe493f4abd93f397d3 380 SUPERFAMILY SSF55424 315 378 3.71E-17 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS05855 186df5f524e9aff641ae1d6fc1fb4767 184 Gene3D G3DSA:3.90.470.20 8 77 4.9E-9 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS05855 186df5f524e9aff641ae1d6fc1fb4767 184 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 8 75 4.7E-6 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS05855 186df5f524e9aff641ae1d6fc1fb4767 184 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 11 75 9.0E-5 T 09-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 UA74_RS05855 186df5f524e9aff641ae1d6fc1fb4767 184 SUPERFAMILY SSF56214 8 77 4.01E-8 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS24535 204c3d63f389f37faf3e067c403c9bfb 263 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 8.0E-74 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS24535 204c3d63f389f37faf3e067c403c9bfb 263 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 09-03-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 UA74_RS24535 204c3d63f389f37faf3e067c403c9bfb 263 SUPERFAMILY SSF64005 34 257 1.2E-83 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS24535 204c3d63f389f37faf3e067c403c9bfb 263 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 2.4E-74 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS24535 204c3d63f389f37faf3e067c403c9bfb 263 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 37.963 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS24535 204c3d63f389f37faf3e067c403c9bfb 263 Gene3D G3DSA:3.40.1180.10 30 262 2.1E-89 T 09-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_RS11455 30ac66c7b581934718fc432c27bdfcb9 130 Pfam PF01597 Glycine cleavage H-protein 8 126 3.2E-43 T 09-03-2017 IPR002930 Glycine cleavage system H-protein UA74_RS11455 30ac66c7b581934718fc432c27bdfcb9 130 Gene3D G3DSA:2.40.50.100 7 127 6.8E-49 T 09-03-2017 UA74_RS11455 30ac66c7b581934718fc432c27bdfcb9 130 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 30.348 T 09-03-2017 IPR002930 Glycine cleavage system H-protein UA74_RS11455 30ac66c7b581934718fc432c27bdfcb9 130 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 127 1.7E-48 T 09-03-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 UA74_RS11455 30ac66c7b581934718fc432c27bdfcb9 130 SUPERFAMILY SSF51230 4 127 1.96E-42 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS11455 30ac66c7b581934718fc432c27bdfcb9 130 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 11 165 40.598 T 09-03-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 133 139 - T 09-03-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 84 164 8.4E-36 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 13 79 1.3E-6 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 83 162 7.9E-36 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 SUPERFAMILY SSF53155 12 88 3.14E-19 T 09-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 SUPERFAMILY SSF46767 82 164 3.79E-34 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS14685 c0dccec83476fd1708a98f7112161ed1 172 Gene3D G3DSA:1.10.10.10 81 165 2.5E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 159 166 - T 09-03-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 PIRSF PIRSF000349 1 201 8.0E-77 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 192 2.9E-34 T 09-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 Gene3D G3DSA:1.10.287.990 20 83 2.3E-23 T 09-03-2017 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 SUPERFAMILY SSF46609 2 84 2.09E-32 T 09-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 SUPERFAMILY SSF54719 83 196 1.1E-42 T 09-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 83 9.1E-32 T 09-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.3E-22 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 66 79 1.3E-22 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.3E-22 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 119 127 1.3E-22 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11440 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 157 169 1.3E-22 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS17475 f84aed6a952b8174c3efb43aa9869fea 375 SUPERFAMILY SSF56601 38 353 6.16E-66 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS17475 f84aed6a952b8174c3efb43aa9869fea 375 Gene3D G3DSA:3.40.710.10 39 353 6.8E-66 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS17475 f84aed6a952b8174c3efb43aa9869fea 375 Pfam PF00144 Beta-lactamase 47 352 1.2E-44 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS02245 7ce7689ffb7c45ca3768cf413a2b1982 70 Pfam PF12728 Helix-turn-helix domain 16 64 1.4E-14 T 09-03-2017 UA74_RS02245 7ce7689ffb7c45ca3768cf413a2b1982 70 SUPERFAMILY SSF46955 15 63 1.48E-5 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS02245 7ce7689ffb7c45ca3768cf413a2b1982 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 63 5.3E-20 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_RS02245 7ce7689ffb7c45ca3768cf413a2b1982 70 Gene3D G3DSA:1.10.10.10 16 62 6.7E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17190 72e75b7bc5c4e37983583b6e4ae8169f 331 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 8 307 1.8E-114 T 09-03-2017 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA UA74_RS17190 72e75b7bc5c4e37983583b6e4ae8169f 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 291 1.1E-53 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS17190 72e75b7bc5c4e37983583b6e4ae8169f 331 SUPERFAMILY SSF53686 21 312 1.44E-69 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS17190 72e75b7bc5c4e37983583b6e4ae8169f 331 Gene3D G3DSA:3.40.50.1100 35 138 9.0E-22 T 09-03-2017 UA74_RS17190 72e75b7bc5c4e37983583b6e4ae8169f 331 Gene3D G3DSA:3.40.50.1100 139 311 2.8E-48 T 09-03-2017 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF55945 211 314 6.59E-18 T 09-03-2017 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SMART SM01009 210 334 3.3E-41 T 09-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SMART SM00342 101 184 9.0E-17 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SMART SM00478 344 519 1.4E-4 T 09-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Pfam PF06029 AlkA N-terminal domain 211 334 1.9E-29 T 09-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:1.10.340.30 335 461 1.3E-30 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:1.10.1670.10 463 518 3.0E-11 T 09-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF57884 6 83 2.35E-30 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Pfam PF12833 Helix-turn-helix domain 107 186 1.3E-16 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF48150 325 516 1.41E-33 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:3.40.10.10 7 82 2.6E-32 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:1.10.10.60 83 138 6.1E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Pfam PF02805 Metal binding domain of Ada 8 72 5.9E-29 T 09-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:1.10.10.60 139 188 2.2E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF46689 137 187 2.78E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07890 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:3.30.310.20 211 334 1.0E-30 T 09-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal UA74_RS17785 1ef2efec02844f903427004468ea8318 300 SUPERFAMILY SSF88946 6 87 1.77E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17785 1ef2efec02844f903427004468ea8318 300 Gene3D G3DSA:1.10.1740.10 4 76 1.2E-15 T 09-03-2017 UA74_RS17785 1ef2efec02844f903427004468ea8318 300 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 169 2.4E-17 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17785 1ef2efec02844f903427004468ea8318 300 Pfam PF04542 Sigma-70 region 2 11 74 3.4E-14 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17785 1ef2efec02844f903427004468ea8318 300 Gene3D G3DSA:3.10.450.50 180 290 1.2E-6 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS17785 1ef2efec02844f903427004468ea8318 300 SUPERFAMILY SSF54427 182 292 2.47E-10 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS17785 1ef2efec02844f903427004468ea8318 300 SUPERFAMILY SSF88659 109 170 6.54E-8 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17785 1ef2efec02844f903427004468ea8318 300 Gene3D G3DSA:1.10.10.10 110 170 9.9E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17785 1ef2efec02844f903427004468ea8318 300 Pfam PF08281 Sigma-70, region 4 116 167 5.1E-6 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07795 87e969a58d765df623046dca055c86ad 608 Pfam PF00733 Asparagine synthase 207 569 3.7E-32 T 09-03-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UA74_RS07795 87e969a58d765df623046dca055c86ad 608 SUPERFAMILY SSF52402 188 347 3.49E-25 T 09-03-2017 UA74_RS07795 87e969a58d765df623046dca055c86ad 608 SUPERFAMILY SSF52402 445 560 3.49E-25 T 09-03-2017 UA74_RS07795 87e969a58d765df623046dca055c86ad 608 Gene3D G3DSA:3.60.20.10 114 192 1.3E-4 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS07795 87e969a58d765df623046dca055c86ad 608 Gene3D G3DSA:3.40.50.620 445 591 1.8E-27 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS07795 87e969a58d765df623046dca055c86ad 608 Gene3D G3DSA:3.40.50.620 193 345 1.8E-27 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 Gene3D G3DSA:3.40.50.2300 6 156 4.5E-36 T 09-03-2017 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 SUPERFAMILY SSF46894 148 211 9.86E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 SUPERFAMILY SSF52172 6 134 5.83E-32 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 Gene3D G3DSA:1.10.10.10 157 210 3.0E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 SMART SM00421 148 205 9.1E-23 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 3.6E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 Pfam PF00072 Response regulator receiver domain 8 120 3.1E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 SMART SM00448 6 119 5.8E-29 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS03410 8e680ea5688b278171b23685a17f5fcf 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28795 b533bd51f66779ff0abe1c03a8af2024 426 Pfam PF04286 Protein of unknown function (DUF445) 62 424 1.2E-109 T 09-03-2017 IPR007383 Protein of unknown function DUF445 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 SUPERFAMILY SSF46785 8 118 3.48E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.7E-18 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 Gene3D G3DSA:1.10.10.10 7 89 7.1E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 SUPERFAMILY SSF53850 96 303 5.97E-32 T 09-03-2017 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 4.7E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 4.7E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 4.7E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 Gene3D G3DSA:3.40.190.10 184 271 3.4E-34 T 09-03-2017 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 Gene3D G3DSA:3.40.190.10 97 183 2.5E-16 T 09-03-2017 UA74_RS20540 f210005b692fced33b759b87c3e8b950 311 Pfam PF03466 LysR substrate binding domain 95 299 2.1E-32 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS18095 4daf3f0b8c712388ed4f2d6014506157 170 Pfam PF12802 MarR family 47 95 9.0E-8 T 09-03-2017 UA74_RS18095 4daf3f0b8c712388ed4f2d6014506157 170 SUPERFAMILY SSF46785 11 124 2.73E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18095 4daf3f0b8c712388ed4f2d6014506157 170 Gene3D G3DSA:1.10.10.10 11 129 8.1E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 Gene3D G3DSA:3.40.50.720 329 386 2.7E-77 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 Gene3D G3DSA:3.40.50.720 10 226 2.7E-77 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 Pfam PF01658 Myo-inositol-1-phosphate synthase 226 330 4.9E-24 T 09-03-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 PIRSF PIRSF015578 3 386 2.9E-77 T 09-03-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 Gene3D G3DSA:3.30.360.10 227 326 4.9E-25 T 09-03-2017 UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 Pfam PF07994 Myo-inositol-1-phosphate synthase 10 385 3.1E-43 T 09-03-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 SUPERFAMILY SSF55347 225 329 2.35E-26 T 09-03-2017 UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 SUPERFAMILY SSF51735 11 224 1.5E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27275 66c3d1f7da2f9fc1e16567b9fb26ff70 387 SUPERFAMILY SSF51735 329 385 1.5E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00915 39fc92e57eae012422981eb693f3851d 299 SUPERFAMILY SSF161098 91 277 7.59E-25 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00915 39fc92e57eae012422981eb693f3851d 299 Gene3D G3DSA:1.10.3720.10 89 290 4.4E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00915 39fc92e57eae012422981eb693f3851d 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 287 2.6E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS13275 dfcdf7325c4ddbccc5cedd0b2155e27c 145 SUPERFAMILY SSF55961 1 142 8.45E-17 T 09-03-2017 UA74_RS13275 dfcdf7325c4ddbccc5cedd0b2155e27c 145 Gene3D G3DSA:3.30.530.20 1 139 2.9E-6 T 09-03-2017 IPR023393 START-like domain UA74_RS13275 dfcdf7325c4ddbccc5cedd0b2155e27c 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 141 3.1E-7 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 Gene3D G3DSA:3.20.20.70 12 300 1.4E-97 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 140 157 1.9E-28 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 1.9E-28 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 1.9E-28 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 83 101 1.9E-28 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 12 297 53.025 T 09-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 145 175 - T 09-03-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 50 67 - T 09-03-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 PIRSF PIRSF001365 10 304 2.9E-73 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 Pfam PF00701 Dihydrodipicolinate synthetase family 13 293 2.5E-73 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 SMART SM01130 12 299 6.9E-111 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 SUPERFAMILY SSF51569 12 300 5.97E-86 T 09-03-2017 UA74_RS09570 0fd412ba575fa272be1f22ab1147834a 318 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 292 5.7E-79 T 09-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS12875 f617f1313e13aeb7e120a151ec0c3c93 510 Pfam PF07690 Major Facilitator Superfamily 9 355 8.5E-21 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS12875 f617f1313e13aeb7e120a151ec0c3c93 510 Gene3D G3DSA:1.20.1250.20 3 189 3.4E-17 T 09-03-2017 UA74_RS12875 f617f1313e13aeb7e120a151ec0c3c93 510 Gene3D G3DSA:1.20.1250.20 224 391 1.1E-14 T 09-03-2017 UA74_RS12875 f617f1313e13aeb7e120a151ec0c3c93 510 SUPERFAMILY SSF103473 2 395 2.09E-38 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF57770 140 173 4.58E-11 T 09-03-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 253 264 3.3E-25 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.3E-25 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 399 410 3.3E-25 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.3E-25 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.3E-25 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 3.3E-25 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF52374 174 399 7.11E-92 T 09-03-2017 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF52374 6 139 7.11E-92 T 09-03-2017 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 543 3.7E-147 T 09-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 Gene3D G3DSA:3.40.50.620 6 142 3.1E-90 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 Gene3D G3DSA:3.40.50.620 181 394 3.1E-90 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 Gene3D G3DSA:2.20.28.20 143 174 1.0E-17 T 09-03-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 Gene3D G3DSA:1.10.730.10 395 581 9.8E-50 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 Pfam PF09334 tRNA synthetases class I (M) 6 411 8.2E-144 T 09-03-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 592 38.021 T 09-03-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF47323 400 527 2.43E-32 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS03435 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF47323 555 581 2.43E-32 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS06635 8605490f12564f1bf9a489807c21449d 284 SUPERFAMILY SSF47413 10 69 1.04E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06635 8605490f12564f1bf9a489807c21449d 284 Pfam PF13560 Helix-turn-helix domain 13 75 3.6E-11 T 09-03-2017 UA74_RS06635 8605490f12564f1bf9a489807c21449d 284 Gene3D G3DSA:1.10.260.40 10 71 5.0E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23095 414a4b85bc9941826e82cff99a6a88bc 372 Pfam PF13353 4Fe-4S single cluster domain 34 134 7.6E-11 T 09-03-2017 UA74_RS23095 414a4b85bc9941826e82cff99a6a88bc 372 Pfam PF04055 Radical SAM superfamily 34 165 7.0E-19 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS23095 414a4b85bc9941826e82cff99a6a88bc 372 SUPERFAMILY SSF102114 25 334 3.66E-44 T 09-03-2017 UA74_RS23095 414a4b85bc9941826e82cff99a6a88bc 372 Gene3D G3DSA:3.20.20.70 22 342 8.0E-47 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS14145 29c3286f27687deb15ca38723d88493e 472 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 190 243 1.3E-5 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_RS14145 29c3286f27687deb15ca38723d88493e 472 Gene3D G3DSA:3.40.50.300 51 255 2.0E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14145 29c3286f27687deb15ca38723d88493e 472 SUPERFAMILY SSF52540 51 341 4.89E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 Pfam PF08402 TOBE domain 282 359 1.1E-8 T 09-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 Gene3D G3DSA:3.40.50.300 3 238 6.3E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 SUPERFAMILY SSF50331 236 367 2.07E-25 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 Pfam PF00005 ABC transporter 20 161 3.6E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 SUPERFAMILY SSF52540 4 242 8.4E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 Gene3D G3DSA:2.40.50.100 239 286 4.2E-10 T 09-03-2017 UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 Gene3D G3DSA:2.40.50.100 353 367 4.2E-10 T 09-03-2017 UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 SMART SM00382 28 211 4.3E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS20135 e0fab47e3ec9c39a1805e36ce79f165f 379 Gene3D G3DSA:2.40.50.140 287 350 1.1E-13 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS11410 24eb27d25899b2198a724ff9ac7fea27 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 1.7E-21 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS11410 24eb27d25899b2198a724ff9ac7fea27 209 Gene3D G3DSA:3.60.15.10 24 191 1.7E-45 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS11410 24eb27d25899b2198a724ff9ac7fea27 209 SUPERFAMILY SSF56281 21 201 5.46E-43 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS11410 24eb27d25899b2198a724ff9ac7fea27 209 SMART SM00849 24 188 3.1E-34 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 27.912 T 09-03-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 Gene3D G3DSA:1.10.8.10 144 199 7.1E-20 T 09-03-2017 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 Gene3D G3DSA:1.10.150.20 68 134 1.6E-26 T 09-03-2017 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 SUPERFAMILY SSF50249 1 62 1.26E-12 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 Gene3D G3DSA:2.40.50.140 1 63 3.0E-20 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 Pfam PF01330 RuvA N terminal domain 1 61 8.2E-17 T 09-03-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 SMART SM00278 107 126 0.8 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 SMART SM00278 72 91 22.0 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 SUPERFAMILY SSF47781 65 132 3.34E-19 T 09-03-2017 IPR010994 RuvA domain 2-like UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 SUPERFAMILY SSF46929 148 198 3.01E-8 T 09-03-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 Pfam PF14520 Helix-hairpin-helix domain 71 129 2.4E-14 T 09-03-2017 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 179 1.3E-37 T 09-03-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 UA74_RS11155 b74a3d7982bef4877cd344fb5e262d51 199 Pfam PF07499 RuvA, C-terminal domain 149 195 6.5E-9 T 09-03-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 UA74_RS16360 80f75766d85c8021e6c4c2f31db2baf7 213 Pfam PF13565 Homeodomain-like domain 109 166 3.4E-9 T 09-03-2017 UA74_RS16360 80f75766d85c8021e6c4c2f31db2baf7 213 SUPERFAMILY SSF46689 103 171 6.99E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 09-03-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 Gene3D G3DSA:3.40.190.10 1 106 8.1E-33 T 09-03-2017 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 189 280 7.1E-27 T 09-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 281 30.02 T 09-03-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 Pfam PF08029 HisG, C-terminal domain 206 276 1.1E-23 T 09-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 Pfam PF01634 ATP phosphoribosyltransferase 49 201 3.6E-37 T 09-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 SUPERFAMILY SSF53850 1 206 2.02E-58 T 09-03-2017 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 Gene3D G3DSA:3.40.190.10 107 172 7.4E-25 T 09-03-2017 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 2.1E-49 T 09-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 Gene3D G3DSA:3.30.70.120 209 280 6.5E-25 T 09-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UA74_RS12895 ba6eafe9a4bc05323843fbde143adfef 281 SUPERFAMILY SSF54913 209 280 1.22E-19 T 09-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 Pfam PF00067 Cytochrome P450 188 377 4.7E-22 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 298 325 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 197 219 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 147 163 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 356 367 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 326 341 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 347 356 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 100 111 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 281 292 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 164 179 5.9E-46 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 SUPERFAMILY SSF48264 21 408 3.93E-85 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 246 263 2.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 347 356 2.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 281 292 2.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 356 367 2.3E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 Gene3D G3DSA:1.10.630.10 19 408 1.8E-110 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17620 61865cddbd60b2b89ec88855a32ac692 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS13075 854e6d2b0fc4a2598ef7bd973bb941ce 284 PIRSF PIRSF018249 4 284 2.5E-84 T 09-03-2017 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 UA74_RS13075 854e6d2b0fc4a2598ef7bd973bb941ce 284 Pfam PF13649 Methyltransferase domain 98 182 4.3E-7 T 09-03-2017 UA74_RS13075 854e6d2b0fc4a2598ef7bd973bb941ce 284 SUPERFAMILY SSF53335 17 235 5.83E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13075 854e6d2b0fc4a2598ef7bd973bb941ce 284 Gene3D G3DSA:3.40.50.150 76 200 2.5E-14 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06795 b5b7f253bce7f0fecb5085ee670ddd0e 324 SUPERFAMILY SSF103481 217 314 2.94E-9 T 09-03-2017 UA74_RS06795 b5b7f253bce7f0fecb5085ee670ddd0e 324 Pfam PF00892 EamA-like transporter family 180 307 2.5E-13 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SUPERFAMILY SSF55307 201 315 8.7E-43 T 09-03-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SMART SM00864 10 202 1.4E-108 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 09-03-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Gene3D G3DSA:3.40.50.1440 11 211 2.7E-91 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 314 7.8E-127 T 09-03-2017 IPR000158 Cell division protein FtsZ GO:0005525 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SMART SM00865 204 321 4.8E-56 T 09-03-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 3.8E-38 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Pfam PF12327 FtsZ family, C-terminal domain 219 313 3.7E-35 T 09-03-2017 IPR024757 Cell division protein FtsZ, C-terminal UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 95 115 9.6E-51 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 186 208 9.6E-51 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 209 230 9.6E-51 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 123 144 9.6E-51 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SUPERFAMILY SSF52490 9 205 1.01E-65 T 09-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 09-03-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 386 38.326 T 09-03-2017 IPR000158 Cell division protein FtsZ GO:0005525 UA74_RS09775 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Gene3D G3DSA:3.30.1330.20 212 314 5.5E-48 T 09-03-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 UA74_RS07330 bfac134f9b9a7321646b6560c13573dd 111 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 6.7E-27 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_RS07330 bfac134f9b9a7321646b6560c13573dd 111 Pfam PF12823 Domain of unknown function (DUF3817) 7 94 1.6E-26 T 09-03-2017 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 342 352 1.7E-7 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 230 247 1.7E-7 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 275 293 1.7E-7 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 352 375 1.7E-7 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00385 P450 superfamily signature 343 352 6.4E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00385 P450 superfamily signature 241 258 6.4E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00385 P450 superfamily signature 352 363 6.4E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 SUPERFAMILY SSF48264 16 403 4.71E-91 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 Gene3D G3DSA:1.10.630.10 13 403 2.1E-120 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS18220 1c618676ca8bb047c8dc418743b72d0e 403 Pfam PF00067 Cytochrome P450 274 372 3.4E-17 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28105 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 Gene3D G3DSA:3.40.50.150 18 249 6.2E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28105 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 166 181 - T 09-03-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_RS28105 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 SUPERFAMILY SSF53335 7 213 2.29E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28105 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 14 219 1.3E-27 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1137 1533 8.8E-112 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 61 465 2.8E-132 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF52777 659 836 3.89E-45 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00550 Phosphopantetheine attachment site 1619 1683 4.2E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00550 Phosphopantetheine attachment site 552 612 4.7E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:1.10.1200.10 551 617 3.5E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:1.10.1200.10 1622 1684 8.8E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.980 1276 1423 9.1E-37 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF52777 843 1101 2.89E-47 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00668 Condensation domain 655 951 2.0E-61 T 09-03-2017 IPR001242 Condensation domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 ProSitePatterns PS00012 Phosphopantetheine attachment site. 574 589 - T 09-03-2017 IPR006162 Phosphopantetheine attachment site UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.980 191 352 1.0E-44 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF56801 9 562 4.84E-152 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 527 8.5E-10 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00501 AMP-binding enzyme 41 441 3.3E-97 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00501 AMP-binding enzyme 1117 1510 2.0E-78 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF53474 1693 1918 1.28E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF56801 1076 1625 1.57E-130 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SMART SM00823 Phosphopantetheine attachment site 1617 1688 0.0015 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SMART SM00823 Phosphopantetheine attachment site 550 618 0.018 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1254 1265 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:2.30.38.10 353 431 1.0E-25 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:2.30.38.10 1424 1500 1.7E-22 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF47336 1610 1684 1.96E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.980 1110 1275 3.9E-35 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF47336 544 612 2.22E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00975 Thioesterase domain 1708 1807 1.3E-21 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.30.300.30 437 550 1.1E-30 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.30.300.30 1506 1621 4.9E-25 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.980 36 190 8.2E-44 T 09-03-2017 UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.1820 1853 1919 2.6E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14930 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.1820 1694 1809 2.6E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 9.0E-112 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 Gene3D G3DSA:3.40.50.2020 9 166 5.7E-67 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 SUPERFAMILY SSF53271 77 314 6.78E-60 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 SMART SM01400 12 128 1.0E-67 T 09-03-2017 UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 323 44.284 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 5.9E-43 T 09-03-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 09-03-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 Gene3D G3DSA:3.40.50.2020 167 293 1.3E-41 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS03640 dffbc93dfb7bb7f41090b68d2de041dc 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 4.8E-20 T 09-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UA74_RS05440 8050612f04d0c330fcea1d94f1624245 196 Gene3D G3DSA:1.10.357.10 11 193 8.9E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS05440 8050612f04d0c330fcea1d94f1624245 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 2.5E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05440 8050612f04d0c330fcea1d94f1624245 196 SUPERFAMILY SSF48498 88 187 2.76E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS05440 8050612f04d0c330fcea1d94f1624245 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 5.1E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05440 8050612f04d0c330fcea1d94f1624245 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 5.1E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05440 8050612f04d0c330fcea1d94f1624245 196 SUPERFAMILY SSF46689 9 88 9.93E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS26355 73e04a8bc84b786a9763efa9b75651ab 202 Pfam PF12079 Protein of unknown function (DUF3558) 2 193 5.7E-9 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS13340 443768b86644f8e63eb4832197b119ec 274 SUPERFAMILY SSF52540 5 232 1.51E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13340 443768b86644f8e63eb4832197b119ec 274 SMART SM00382 31 220 7.6E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13340 443768b86644f8e63eb4832197b119ec 274 Gene3D G3DSA:3.40.50.300 4 238 7.5E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13340 443768b86644f8e63eb4832197b119ec 274 Pfam PF00005 ABC transporter 23 170 1.2E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13340 443768b86644f8e63eb4832197b119ec 274 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS15085 6139ae0fc4e3982e70bee7da0022e977 147 Gene3D G3DSA:3.10.450.50 1 138 5.5E-49 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS15085 6139ae0fc4e3982e70bee7da0022e977 147 SUPERFAMILY SSF54427 5 132 3.25E-33 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS15085 6139ae0fc4e3982e70bee7da0022e977 147 Pfam PF12680 SnoaL-like domain 9 117 1.4E-15 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS16195 a9d347efe5123b3c6e6efa6035a43c49 435 Gene3D G3DSA:3.30.450.90 77 177 1.1E-11 T 09-03-2017 UA74_RS16195 a9d347efe5123b3c6e6efa6035a43c49 435 SUPERFAMILY SSF52540 65 365 1.18E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16195 a9d347efe5123b3c6e6efa6035a43c49 435 Gene3D G3DSA:3.40.50.300 184 399 1.4E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16195 a9d347efe5123b3c6e6efa6035a43c49 435 Pfam PF00437 Type II/IV secretion system protein 82 365 4.2E-50 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 UA74_RS01585 cc313c8ff210857f900171ec1c670ca1 115 Pfam PF11774 Lsr2 1 114 1.2E-42 T 09-03-2017 IPR024412 Lsr2 UA74_RS01585 cc313c8ff210857f900171ec1c670ca1 115 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 113 2.0E-27 T 09-03-2017 IPR024412 Lsr2 UA74_RS26705 29cc76bd104c61ae9aa01445099dc4e5 258 Pfam PF00588 SpoU rRNA Methylase family 109 246 2.8E-29 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_RS26705 29cc76bd104c61ae9aa01445099dc4e5 258 Gene3D G3DSA:3.40.1280.10 106 255 7.3E-43 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS26705 29cc76bd104c61ae9aa01445099dc4e5 258 SMART SM00967 16 93 1.3E-9 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS26705 29cc76bd104c61ae9aa01445099dc4e5 258 SUPERFAMILY SSF75217 93 255 1.05E-36 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS26705 29cc76bd104c61ae9aa01445099dc4e5 258 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 17 91 3.7E-13 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS26705 29cc76bd104c61ae9aa01445099dc4e5 258 Gene3D G3DSA:3.30.1330.30 16 87 3.4E-13 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS26705 29cc76bd104c61ae9aa01445099dc4e5 258 SUPERFAMILY SSF55315 11 87 2.0E-11 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS07490 7a24e598d40a22a7293f3b1ac3386b84 310 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 179 298 1.2E-24 T 09-03-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 UA74_RS07490 7a24e598d40a22a7293f3b1ac3386b84 310 SUPERFAMILY SSF51735 2 132 4.73E-11 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07490 7a24e598d40a22a7293f3b1ac3386b84 310 Gene3D G3DSA:1.10.1040.10 186 299 2.9E-27 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS07490 7a24e598d40a22a7293f3b1ac3386b84 310 SUPERFAMILY SSF48179 179 298 3.74E-23 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS07490 7a24e598d40a22a7293f3b1ac3386b84 310 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 151 7.7E-27 T 09-03-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 UA74_RS07490 7a24e598d40a22a7293f3b1ac3386b84 310 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 301 3.1E-59 T 09-03-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 UA74_RS07490 7a24e598d40a22a7293f3b1ac3386b84 310 Gene3D G3DSA:3.40.50.720 2 185 1.1E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 107 126 2.3E-13 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 144 157 2.3E-13 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 347 363 2.3E-13 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 348 358 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 Pfam PF00082 Subtilase family 109 397 4.8E-40 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 Gene3D G3DSA:3.40.50.200 83 408 2.2E-74 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 Gene3D G3DSA:3.40.50.200 31 51 2.2E-74 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 96 468 5.4E-111 T 09-03-2017 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 112 122 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 148 158 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS28250 b0c8ae575549b03d8b054f07b7791546 473 SUPERFAMILY SSF52743 88 408 6.02E-72 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 Gene3D G3DSA:3.40.50.720 27 261 1.2E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 SUPERFAMILY SSF51735 27 277 4.39E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 Pfam PF00106 short chain dehydrogenase 31 225 1.1E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 31 48 5.0E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 5.0E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 5.0E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.0E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS30220 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 5.0E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05780 79977d1ad23250be2bddc7a37c1ec688 167 Pfam PF00293 NUDIX domain 16 129 3.1E-15 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS05780 79977d1ad23250be2bddc7a37c1ec688 167 SUPERFAMILY SSF55811 16 138 4.33E-22 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS05780 79977d1ad23250be2bddc7a37c1ec688 167 Gene3D G3DSA:3.90.79.10 15 138 2.6E-21 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS05780 79977d1ad23250be2bddc7a37c1ec688 167 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS21870 a785f4a8d0ae0aaee262d73c0e299d1e 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 218 9.1E-27 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS21870 a785f4a8d0ae0aaee262d73c0e299d1e 219 Gene3D G3DSA:1.10.10.10 127 218 3.6E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21870 a785f4a8d0ae0aaee262d73c0e299d1e 219 SMART SM00862 147 218 2.6E-30 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS21870 a785f4a8d0ae0aaee262d73c0e299d1e 219 SMART SM00448 2 113 9.1E-39 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21870 a785f4a8d0ae0aaee262d73c0e299d1e 219 Gene3D G3DSA:3.40.50.2300 2 118 1.9E-34 T 09-03-2017 UA74_RS21870 a785f4a8d0ae0aaee262d73c0e299d1e 219 Pfam PF00072 Response regulator receiver domain 4 114 1.2E-24 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21870 a785f4a8d0ae0aaee262d73c0e299d1e 219 SUPERFAMILY SSF52172 1 176 3.15E-36 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 09-03-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 Pfam PF00203 Ribosomal protein S19 3 83 2.1E-36 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.0E-23 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.0E-23 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.0E-23 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 SUPERFAMILY SSF54570 3 84 4.58E-35 T 09-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 Gene3D G3DSA:3.30.860.10 1 92 2.2E-40 T 09-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.2E-47 T 09-03-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 PIRSF PIRSF002144 1 93 2.5E-30 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02950 d901552bec15744b79ad68d27e93f833 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.002 T 09-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS04175 fc5fa01c2440023f86b38591c97639ed 76 Pfam PF02609 Exonuclease VII small subunit 12 62 1.2E-17 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS04175 fc5fa01c2440023f86b38591c97639ed 76 SUPERFAMILY SSF116842 6 65 1.44E-16 T 09-03-2017 UA74_RS04175 fc5fa01c2440023f86b38591c97639ed 76 PIRSF PIRSF006488 2 76 2.4E-23 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS04175 fc5fa01c2440023f86b38591c97639ed 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 9 50 7.0E-13 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS04175 fc5fa01c2440023f86b38591c97639ed 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 12 65 1.6E-20 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS04175 fc5fa01c2440023f86b38591c97639ed 76 Gene3D G3DSA:1.10.287.1040 7 67 3.1E-22 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS04175 fc5fa01c2440023f86b38591c97639ed 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 11 71 13.877 T 09-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_RS09915 20dc0f5e9cd2140035ad3c8be9d43819 234 SUPERFAMILY SSF55811 21 141 9.48E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS09915 20dc0f5e9cd2140035ad3c8be9d43819 234 Pfam PF00293 NUDIX domain 25 126 4.6E-10 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS09915 20dc0f5e9cd2140035ad3c8be9d43819 234 SUPERFAMILY SSF46785 145 216 3.26E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09915 20dc0f5e9cd2140035ad3c8be9d43819 234 Gene3D G3DSA:1.10.10.10 138 213 1.7E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09915 20dc0f5e9cd2140035ad3c8be9d43819 234 Gene3D G3DSA:3.90.79.10 10 133 7.1E-27 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS26250 5916b653c9c11a931e3d6a8aaee48b42 217 SUPERFAMILY SSF55021 3 69 2.5E-6 T 09-03-2017 UA74_RS28980 4a3f1a3233bf638e8192d3143a0c240e 297 SUPERFAMILY SSF53448 2 212 7.03E-41 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS28980 4a3f1a3233bf638e8192d3143a0c240e 297 Pfam PF00535 Glycosyl transferase family 2 3 132 4.9E-25 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS28980 4a3f1a3233bf638e8192d3143a0c240e 297 Gene3D G3DSA:3.90.550.10 3 211 1.0E-39 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS23570 879f8d3f94a20dc176d2937d1d6b423f 484 Gene3D G3DSA:3.40.309.10 253 423 6.5E-42 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS23570 879f8d3f94a20dc176d2937d1d6b423f 484 Pfam PF00171 Aldehyde dehydrogenase family 7 456 3.2E-101 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS23570 879f8d3f94a20dc176d2937d1d6b423f 484 Gene3D G3DSA:3.40.605.10 6 252 2.0E-59 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS23570 879f8d3f94a20dc176d2937d1d6b423f 484 SUPERFAMILY SSF53720 6 460 9.69E-104 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS04555 1aa97cdde6b2a79ebe13a436e82c4f25 63 Pfam PF04149 Domain of unknown function (DUF397) 4 54 2.2E-13 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS30250 edb196c75d4313f8de1f0f6443d3eff5 285 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 137 238 5.4E-19 T 09-03-2017 IPR000160 GGDEF domain UA74_RS30250 edb196c75d4313f8de1f0f6443d3eff5 285 Gene3D G3DSA:3.30.450.20 19 118 7.4E-4 T 09-03-2017 UA74_RS30250 edb196c75d4313f8de1f0f6443d3eff5 285 SMART SM00267 125 282 5.8E-7 T 09-03-2017 IPR000160 GGDEF domain UA74_RS30250 edb196c75d4313f8de1f0f6443d3eff5 285 Pfam PF00990 Diguanylate cyclase, GGDEF domain 139 236 7.4E-22 T 09-03-2017 IPR000160 GGDEF domain UA74_RS30250 edb196c75d4313f8de1f0f6443d3eff5 285 SUPERFAMILY SSF55073 142 281 7.69E-23 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS30250 edb196c75d4313f8de1f0f6443d3eff5 285 Gene3D G3DSA:3.30.70.270 139 279 1.2E-24 T 09-03-2017 UA74_RS24545 56fb919cb8e90cd246cd22270a7fd434 310 SUPERFAMILY SSF52540 3 234 2.62E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24545 56fb919cb8e90cd246cd22270a7fd434 310 Gene3D G3DSA:3.40.50.300 3 228 6.8E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24545 56fb919cb8e90cd246cd22270a7fd434 310 Pfam PF00005 ABC transporter 20 157 7.5E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS24545 56fb919cb8e90cd246cd22270a7fd434 310 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS24545 56fb919cb8e90cd246cd22270a7fd434 310 SMART SM00382 28 205 7.7E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS17920 4143f90653450e77628ab03488d46fdd 1404 SUPERFAMILY SSF49785 855 996 5.72E-10 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS17920 4143f90653450e77628ab03488d46fdd 1404 SUPERFAMILY SSF48208 316 780 5.35E-23 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS17920 4143f90653450e77628ab03488d46fdd 1404 Pfam PF07532 Bacterial Ig-like domain (group 4) 1334 1392 4.1E-13 T 09-03-2017 IPR011081 Bacterial Ig-related KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 UA74_RS17920 4143f90653450e77628ab03488d46fdd 1404 Pfam PF00754 F5/8 type C domain 866 989 4.8E-12 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_RS17920 4143f90653450e77628ab03488d46fdd 1404 SUPERFAMILY SSF49785 1101 1246 3.83E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS17920 4143f90653450e77628ab03488d46fdd 1404 Gene3D G3DSA:2.60.120.260 858 994 3.4E-14 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS17920 4143f90653450e77628ab03488d46fdd 1404 Gene3D G3DSA:2.60.120.260 1100 1250 3.3E-4 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS14920 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Gene3D G3DSA:3.10.180.10 9 137 1.9E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14920 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 46 136 2.4E-9 T 09-03-2017 UA74_RS14920 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Gene3D G3DSA:3.10.180.10 153 343 5.4E-56 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14920 0a4b3ac75745b6e3c0375c7a7f2fea71 349 SUPERFAMILY SSF54593 12 337 7.97E-68 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14920 0a4b3ac75745b6e3c0375c7a7f2fea71 349 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 13 344 5.5E-102 T 09-03-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_RS14920 0a4b3ac75745b6e3c0375c7a7f2fea71 349 PIRSF PIRSF009283 1 349 1.4E-106 T 09-03-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_RS14920 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 271 3.4E-13 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS01645 f42f95a8eff0c333b53e85d04f639a0b 266 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 09-03-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_RS01645 f42f95a8eff0c333b53e85d04f639a0b 266 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 236 1.0E-61 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_RS01645 f42f95a8eff0c333b53e85d04f639a0b 266 Gene3D G3DSA:3.90.550.10 3 236 5.7E-64 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS01645 f42f95a8eff0c333b53e85d04f639a0b 266 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 238 28.815 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_RS01645 f42f95a8eff0c333b53e85d04f639a0b 266 SUPERFAMILY SSF53448 3 235 4.77E-51 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS01645 f42f95a8eff0c333b53e85d04f639a0b 266 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 235 1.6E-62 T 09-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 193 215 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 320 335 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 274 285 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 350 361 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 156 171 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 292 319 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 139 155 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 341 350 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 92 103 2.5E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 SUPERFAMILY SSF48264 10 401 5.24E-93 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 341 350 1.2E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 239 256 1.2E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 350 361 1.2E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 274 285 1.2E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 Pfam PF00067 Cytochrome P450 45 370 4.0E-24 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS06945 59a0d228e8b18504662add952e34fc1d 401 Gene3D G3DSA:1.10.630.10 9 401 1.0E-121 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS14645 8d04113649d9ce8b74e0ab6b4d83f499 205 SUPERFAMILY SSF52218 6 199 5.11E-48 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS14645 8d04113649d9ce8b74e0ab6b4d83f499 205 Pfam PF03358 NADPH-dependent FMN reductase 13 133 2.4E-13 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS14645 8d04113649d9ce8b74e0ab6b4d83f499 205 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 5 198 2.4E-44 T 09-03-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 UA74_RS14645 8d04113649d9ce8b74e0ab6b4d83f499 205 Gene3D G3DSA:3.40.50.360 3 203 4.1E-63 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS15040 3f6d9bd06bdd57c3ebc1390361f29d8d 197 SUPERFAMILY SSF52540 15 182 1.94E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15040 3f6d9bd06bdd57c3ebc1390361f29d8d 197 Gene3D G3DSA:3.40.50.300 16 183 1.2E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15040 3f6d9bd06bdd57c3ebc1390361f29d8d 197 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 18 183 4.1E-10 T 09-03-2017 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 UA74_RS25685 66fdafe96740f3ff9c26296468571628 106 Pfam PF14542 GCN5-related N-acetyl-transferase 22 99 2.3E-23 T 09-03-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase UA74_RS25685 66fdafe96740f3ff9c26296468571628 106 Gene3D G3DSA:3.40.630.30 15 101 2.4E-24 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS25685 66fdafe96740f3ff9c26296468571628 106 SUPERFAMILY SSF55729 14 101 2.48E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS30335 f1cf6dc8eb8135298762a9b80ba6bd59 242 SUPERFAMILY SSF48498 91 234 2.2E-16 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS30335 f1cf6dc8eb8135298762a9b80ba6bd59 242 SUPERFAMILY SSF46689 6 79 2.89E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS30335 f1cf6dc8eb8135298762a9b80ba6bd59 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 3.0E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS30335 f1cf6dc8eb8135298762a9b80ba6bd59 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.6E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS30335 f1cf6dc8eb8135298762a9b80ba6bd59 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.6E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS30335 f1cf6dc8eb8135298762a9b80ba6bd59 242 Gene3D G3DSA:1.10.357.10 5 231 8.9E-34 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS24435 175fcd623fd58c14de5adc78af34c39a 320 Pfam PF13280 WYL domain 141 312 7.0E-26 T 09-03-2017 IPR026881 WYL domain UA74_RS24435 175fcd623fd58c14de5adc78af34c39a 320 Pfam PF08279 HTH domain 7 61 1.2E-18 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS24435 175fcd623fd58c14de5adc78af34c39a 320 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS24435 175fcd623fd58c14de5adc78af34c39a 320 Gene3D G3DSA:1.10.10.10 1 64 3.2E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24435 175fcd623fd58c14de5adc78af34c39a 320 SUPERFAMILY SSF46785 5 62 3.95E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22370 9ce7b3445d55a73cba397bf01a61434a 288 Gene3D G3DSA:1.10.3720.10 13 275 1.1E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22370 9ce7b3445d55a73cba397bf01a61434a 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 273 4.2E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22370 9ce7b3445d55a73cba397bf01a61434a 288 SUPERFAMILY SSF161098 20 287 4.77E-64 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01605 8486602e47f41146635b88aab1c79477 282 Gene3D G3DSA:3.30.1600.10 134 188 3.0E-20 T 09-03-2017 IPR026591 Sirtuin family, catalytic core small domain UA74_RS01605 8486602e47f41146635b88aab1c79477 282 Gene3D G3DSA:3.30.1600.10 36 81 3.0E-20 T 09-03-2017 IPR026591 Sirtuin family, catalytic core small domain UA74_RS01605 8486602e47f41146635b88aab1c79477 282 SUPERFAMILY SSF52467 6 276 2.15E-62 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS01605 8486602e47f41146635b88aab1c79477 282 Pfam PF02146 Sir2 family 25 189 4.1E-18 T 09-03-2017 IPR003000 Sirtuin family GO:0070403 UA74_RS01605 8486602e47f41146635b88aab1c79477 282 Gene3D G3DSA:3.40.50.1220 6 35 1.2E-15 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS01605 8486602e47f41146635b88aab1c79477 282 Gene3D G3DSA:3.40.50.1220 90 133 1.2E-15 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS01605 8486602e47f41146635b88aab1c79477 282 Gene3D G3DSA:3.40.50.1220 203 275 1.2E-15 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS01735 3f93c589eecad623fdbeec5b4e9cbfb8 273 SUPERFAMILY SSF52540 10 236 1.88E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01735 3f93c589eecad623fdbeec5b4e9cbfb8 273 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS01735 3f93c589eecad623fdbeec5b4e9cbfb8 273 SMART SM00382 35 222 1.6E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01735 3f93c589eecad623fdbeec5b4e9cbfb8 273 Pfam PF00005 ABC transporter 27 172 6.2E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS01735 3f93c589eecad623fdbeec5b4e9cbfb8 273 Gene3D G3DSA:3.40.50.300 6 238 3.6E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08410 24a00a003b43aa899052427ad7ad4adb 362 Pfam PF00793 DAHP synthetase I family 51 345 1.4E-93 T 09-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 UA74_RS08410 24a00a003b43aa899052427ad7ad4adb 362 PIRSF PIRSF001361 1 360 2.5E-156 T 09-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_RS08410 24a00a003b43aa899052427ad7ad4adb 362 Gene3D G3DSA:3.20.20.70 16 359 1.6E-148 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS08410 24a00a003b43aa899052427ad7ad4adb 362 SUPERFAMILY SSF51569 15 356 2.41E-131 T 09-03-2017 UA74_RS08410 24a00a003b43aa899052427ad7ad4adb 362 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 15 357 2.3E-149 T 09-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_RS12345 b69fb137d45c0dd98edf72b41a3fa5c8 65 SUPERFAMILY SSF54862 3 62 2.89E-16 T 09-03-2017 UA74_RS12345 b69fb137d45c0dd98edf72b41a3fa5c8 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.1E-8 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS12345 b69fb137d45c0dd98edf72b41a3fa5c8 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.1E-8 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS12345 b69fb137d45c0dd98edf72b41a3fa5c8 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.1E-8 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS12345 b69fb137d45c0dd98edf72b41a3fa5c8 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 8.7E-15 T 09-03-2017 UA74_RS12345 b69fb137d45c0dd98edf72b41a3fa5c8 65 Gene3D G3DSA:3.30.70.20 1 63 3.2E-18 T 09-03-2017 UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Gene3D G3DSA:3.20.20.80 193 443 2.5E-25 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 SUPERFAMILY SSF51445 183 453 7.43E-33 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Gene3D G3DSA:2.60.120.260 594 725 4.4E-29 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Gene3D G3DSA:2.60.120.260 45 178 3.5E-34 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Pfam PF00754 F5/8 type C domain 54 166 3.5E-26 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Pfam PF00754 F5/8 type C domain 619 719 1.6E-22 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 279 405 2.3E-6 T 09-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 SUPERFAMILY SSF49785 588 723 4.47E-28 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS19395 2aadb2d1f52a6eeb56479bdeccd82a1f 725 SUPERFAMILY SSF49785 49 171 1.63E-31 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS12435 0bcc0832fe82bb07063c4405ae7b72ab 328 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 1.0E-103 T 09-03-2017 UA74_RS12435 0bcc0832fe82bb07063c4405ae7b72ab 328 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.325 T 09-03-2017 IPR003802 Sporulation regulator WhiA GO:0043937 UA74_RS12435 0bcc0832fe82bb07063c4405ae7b72ab 328 Pfam PF02650 WhiA C-terminal HTH domain 221 303 6.6E-19 T 09-03-2017 IPR023054 Sporulation regulator WhiA, C-terminal UA74_RS12435 0bcc0832fe82bb07063c4405ae7b72ab 328 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 2.3E-24 T 09-03-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain UA74_RS12435 0bcc0832fe82bb07063c4405ae7b72ab 328 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 1.0E-23 T 09-03-2017 UA74_RS23705 0f058f105310dd18bd7cc537581b13a1 211 SMART SM00421 138 200 4.5E-4 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23705 0f058f105310dd18bd7cc537581b13a1 211 SUPERFAMILY SSF46894 132 206 2.96E-10 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS23705 0f058f105310dd18bd7cc537581b13a1 211 Gene3D G3DSA:1.10.10.10 138 206 6.0E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23705 0f058f105310dd18bd7cc537581b13a1 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 182 3.5E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00850 e93d70df85da78d92e25862e603a27ea 174 SUPERFAMILY SSF88946 4 87 1.1E-18 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00850 e93d70df85da78d92e25862e603a27ea 174 Gene3D G3DSA:1.10.10.10 109 171 3.6E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00850 e93d70df85da78d92e25862e603a27ea 174 Pfam PF08281 Sigma-70, region 4 116 166 3.6E-11 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00850 e93d70df85da78d92e25862e603a27ea 174 Gene3D G3DSA:1.10.1740.10 4 87 1.1E-22 T 09-03-2017 UA74_RS00850 e93d70df85da78d92e25862e603a27ea 174 Pfam PF04542 Sigma-70 region 2 9 78 1.5E-14 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00850 e93d70df85da78d92e25862e603a27ea 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 170 1.0E-20 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00850 e93d70df85da78d92e25862e603a27ea 174 SUPERFAMILY SSF88659 108 170 1.63E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS08605 b3b1f368636e90341043a03a2fe8ea76 239 SMART SM00448 1 112 5.6E-38 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS08605 b3b1f368636e90341043a03a2fe8ea76 239 SUPERFAMILY SSF52172 2 171 1.85E-37 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS08605 b3b1f368636e90341043a03a2fe8ea76 239 Gene3D G3DSA:3.40.50.2300 2 120 8.7E-35 T 09-03-2017 UA74_RS08605 b3b1f368636e90341043a03a2fe8ea76 239 SMART SM00862 145 217 4.8E-21 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS08605 b3b1f368636e90341043a03a2fe8ea76 239 Gene3D G3DSA:1.10.10.10 121 217 2.6E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08605 b3b1f368636e90341043a03a2fe8ea76 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.0E-21 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS08605 b3b1f368636e90341043a03a2fe8ea76 239 Pfam PF00072 Response regulator receiver domain 3 113 1.1E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS17945 f6f39ffa484dfcb70a25f3e6c02d53cd 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 3.3E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS17945 f6f39ffa484dfcb70a25f3e6c02d53cd 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 3.3E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS17945 f6f39ffa484dfcb70a25f3e6c02d53cd 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 3.3E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS17945 f6f39ffa484dfcb70a25f3e6c02d53cd 153 SMART SM00347 31 131 6.8E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS17945 f6f39ffa484dfcb70a25f3e6c02d53cd 153 Pfam PF01047 MarR family 39 95 3.1E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS17945 f6f39ffa484dfcb70a25f3e6c02d53cd 153 Gene3D G3DSA:1.10.10.10 5 142 2.6E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17945 f6f39ffa484dfcb70a25f3e6c02d53cd 153 SUPERFAMILY SSF46785 11 142 3.52E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Gene3D G3DSA:3.40.50.920 504 621 8.7E-29 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 SUPERFAMILY SSF52518 2 343 7.23E-64 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 624 40.519 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 2 277 1.4E-103 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Pfam PF02780 Transketolase, C-terminal domain 503 615 4.0E-27 T 09-03-2017 IPR033248 Transketolase, C-terminal domain UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 SUPERFAMILY SSF52518 291 475 7.64E-54 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Gene3D G3DSA:3.40.50.970 330 477 1.2E-30 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 619 2.1E-179 T 09-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 SMART SM00861 313 477 1.6E-53 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Pfam PF02779 Transketolase, pyrimidine binding domain 313 475 4.1E-39 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 SUPERFAMILY SSF52922 504 623 9.03E-25 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 ProSitePatterns PS00802 Transketolase signature 2. 419 435 - T 09-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Gene3D G3DSA:3.40.50.970 16 193 1.6E-56 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS16445 d3f2cf64a56d936696119cd6800b1146 644 Gene3D G3DSA:3.40.50.970 237 329 1.6E-56 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS28670 d66a268f01c1854403a9346cba0f93f5 396 SUPERFAMILY SSF56300 65 353 1.25E-36 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS28670 d66a268f01c1854403a9346cba0f93f5 396 Gene3D G3DSA:3.60.21.10 133 350 1.7E-21 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS28670 d66a268f01c1854403a9346cba0f93f5 396 SMART SM00854 65 313 3.2E-79 T 09-03-2017 IPR019079 Capsule synthesis protein, CapA UA74_RS28670 d66a268f01c1854403a9346cba0f93f5 396 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 66 311 1.5E-64 T 09-03-2017 IPR019079 Capsule synthesis protein, CapA UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 Pfam PF01266 FAD dependent oxidoreductase 5 359 2.2E-51 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 SUPERFAMILY SSF51905 4 217 1.68E-49 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 SUPERFAMILY SSF51905 320 378 1.68E-49 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 SUPERFAMILY SSF54373 215 320 7.45E-20 T 09-03-2017 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 Gene3D G3DSA:3.50.50.60 323 378 2.7E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 Gene3D G3DSA:3.50.50.60 147 209 2.7E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 Gene3D G3DSA:3.50.50.60 3 58 2.7E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 09-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 Gene3D G3DSA:3.30.9.10 214 320 8.8E-50 T 09-03-2017 UA74_RS11415 998a78768a509dfb66146e3a7d940f33 381 Gene3D G3DSA:3.30.9.10 60 146 8.8E-50 T 09-03-2017 UA74_RS27245 33489344b246cb37659a4da4ac3f19a0 465 Gene3D G3DSA:3.40.720.10 2 291 6.9E-50 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 UA74_RS27245 33489344b246cb37659a4da4ac3f19a0 465 SUPERFAMILY SSF53649 2 355 1.27E-74 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 UA74_RS27245 33489344b246cb37659a4da4ac3f19a0 465 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 369 8.3E-59 T 09-03-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 UA74_RS27245 33489344b246cb37659a4da4ac3f19a0 465 Gene3D G3DSA:3.30.1360.110 292 355 2.6E-12 T 09-03-2017 IPR023116 Phosphonoacetate hydrolase, insert domain GO:0047400 UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 SUPERFAMILY SSF52540 12 237 1.98E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 SMART SM00382 38 221 6.1E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 SMART SM00382 287 481 5.7E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 Gene3D G3DSA:3.40.50.300 12 239 1.2E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 Gene3D G3DSA:3.40.50.300 276 494 3.2E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 Pfam PF00005 ABC transporter 279 432 7.9E-21 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 Pfam PF00005 ABC transporter 29 179 7.1E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS26950 283d25a7fd8251a5cb3d39e66f43d2cf 507 SUPERFAMILY SSF52540 277 491 2.62E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 Pfam PF02384 N-6 DNA Methylase 142 438 3.5E-60 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 273 279 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 212 1.2E-13 T 09-03-2017 UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 282 1.2E-13 T 09-03-2017 UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 165 181 1.2E-13 T 09-03-2017 UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 Gene3D G3DSA:3.40.50.150 167 417 4.0E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 SUPERFAMILY SSF53335 2 38 5.14E-114 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 SUPERFAMILY SSF53335 66 472 5.14E-114 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 SUPERFAMILY SSF53335 606 647 5.14E-114 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10310 836727f455eed5a18df258b10a5b3d9c 650 Pfam PF12161 HsdM N-terminal domain 2 130 6.0E-19 T 09-03-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain UA74_RS22160 fc8438d30ad33f5df61e2357b5be27b5 191 SUPERFAMILY SSF55729 79 182 3.78E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS22160 fc8438d30ad33f5df61e2357b5be27b5 191 Gene3D G3DSA:3.40.630.30 90 155 5.1E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS22160 fc8438d30ad33f5df61e2357b5be27b5 191 Pfam PF13673 Acetyltransferase (GNAT) domain 90 155 1.9E-8 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS24895 ab82dbc5a147d3a0261b357cf7e6017e 586 Gene3D G3DSA:1.10.287.1060 74 124 6.0E-4 T 09-03-2017 UA74_RS24895 ab82dbc5a147d3a0261b357cf7e6017e 586 SUPERFAMILY SSF140453 75 157 2.49E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS22225 46bb4d854d42b537a2f68b758c575c80 369 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 68 4.2E-15 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_RS22225 46bb4d854d42b537a2f68b758c575c80 369 Gene3D G3DSA:1.10.3720.10 153 361 4.6E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22225 46bb4d854d42b537a2f68b758c575c80 369 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 176 362 6.0E-27 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22225 46bb4d854d42b537a2f68b758c575c80 369 SUPERFAMILY SSF161098 154 346 1.57E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00425 687d77ed716df186d323b8004083aed3 301 Gene3D G3DSA:3.90.226.10 212 244 1.1E-41 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS00425 687d77ed716df186d323b8004083aed3 301 Gene3D G3DSA:3.90.226.10 23 143 1.1E-41 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS00425 687d77ed716df186d323b8004083aed3 301 SUPERFAMILY SSF52096 176 238 2.89E-39 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS00425 687d77ed716df186d323b8004083aed3 301 SUPERFAMILY SSF52096 23 147 2.89E-39 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS00425 687d77ed716df186d323b8004083aed3 301 Pfam PF01343 Peptidase family S49 104 244 8.9E-33 T 09-03-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 UA74_RS10855 c4fc5b428c6afe74c6a0982d55a82d28 205 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 24 201 2.6E-43 T 09-03-2017 IPR004302 Chitin-binding protein, N-terminal UA74_RS10855 c4fc5b428c6afe74c6a0982d55a82d28 205 SUPERFAMILY SSF81296 24 205 3.5E-48 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS10855 c4fc5b428c6afe74c6a0982d55a82d28 205 Gene3D G3DSA:2.70.50.50 24 204 2.7E-51 T 09-03-2017 UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 SUPERFAMILY SSF53850 88 298 1.03E-31 T 09-03-2017 UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 SUPERFAMILY SSF46785 1 79 1.63E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.8E-20 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 Pfam PF03466 LysR substrate binding domain 87 296 3.4E-30 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 Gene3D G3DSA:3.40.190.10 88 177 2.4E-24 T 09-03-2017 UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 Gene3D G3DSA:1.10.10.10 1 79 6.3E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17465 25104490d2782fcb671287d5a763ea1f 309 Gene3D G3DSA:3.40.190.10 178 264 1.3E-12 T 09-03-2017 UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 SUPERFAMILY SSF50129 1 171 8.22E-56 T 09-03-2017 IPR011032 GroES-like UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 2.0E-33 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 SUPERFAMILY SSF51735 136 281 1.26E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 SMART SM00829 7 327 3.8E-4 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 Pfam PF00107 Zinc-binding dehydrogenase 173 291 6.0E-16 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 Gene3D G3DSA:3.90.180.10 1 163 5.0E-60 T 09-03-2017 IPR011032 GroES-like UA74_RS22995 7f9a8541329270ce090a7310a12a08c6 329 Gene3D G3DSA:3.40.50.720 164 277 3.9E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02760 385d125b88aa0f588bd406ff5c549ba7 291 Pfam PF13460 NAD(P)H-binding 27 186 7.2E-9 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02760 385d125b88aa0f588bd406ff5c549ba7 291 Gene3D G3DSA:3.40.50.720 21 220 1.8E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02760 385d125b88aa0f588bd406ff5c549ba7 291 SUPERFAMILY SSF51735 20 254 6.25E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14420 10f7b0e07f450e0332facf15b5d8f242 458 Gene3D G3DSA:3.40.640.10 79 339 5.9E-24 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS14420 10f7b0e07f450e0332facf15b5d8f242 458 SUPERFAMILY SSF53383 31 442 8.05E-122 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS14420 10f7b0e07f450e0332facf15b5d8f242 458 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 54 375 8.1E-69 T 09-03-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UA74_RS14420 10f7b0e07f450e0332facf15b5d8f242 458 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 33 442 1.1E-180 T 09-03-2017 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 UA74_RS08055 6b4a82c0dd9ec436e0286cf5aa39450e 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 UA74_RS08055 6b4a82c0dd9ec436e0286cf5aa39450e 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS08055 6b4a82c0dd9ec436e0286cf5aa39450e 476 Pfam PF00171 Aldehyde dehydrogenase family 23 474 1.0E-157 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS08055 6b4a82c0dd9ec436e0286cf5aa39450e 476 Gene3D G3DSA:3.40.309.10 261 449 1.2E-63 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS08055 6b4a82c0dd9ec436e0286cf5aa39450e 476 SUPERFAMILY SSF53720 7 474 1.7E-154 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS08055 6b4a82c0dd9ec436e0286cf5aa39450e 476 Gene3D G3DSA:3.40.605.10 8 260 2.6E-83 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 45 56 - T 09-03-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 Gene3D G3DSA:3.20.20.70 29 333 7.7E-81 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 30 356 1.0E-114 T 09-03-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 SMART SM00729 39 244 1.2E-9 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 Pfam PF13353 4Fe-4S single cluster domain 46 125 2.6E-6 T 09-03-2017 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 30 356 41.32 T 09-03-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 SUPERFAMILY SSF102114 29 311 1.57E-74 T 09-03-2017 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 Pfam PF04055 Radical SAM superfamily 45 205 7.3E-30 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS28575 e87c482e601e35db9bd9d4ceddcaa382 356 Pfam PF06463 Molybdenum Cofactor Synthesis C 212 338 3.9E-40 T 09-03-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 Pfam PF00106 short chain dehydrogenase 7 184 1.0E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 Gene3D G3DSA:3.40.50.720 7 211 8.5E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 1.2E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.2E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 1.2E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 209 1.5E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.5E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.5E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.5E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.5E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.5E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 SUPERFAMILY SSF51735 6 211 3.94E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10505 159db1039939ad76af50c128998d3b7c 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 199 0.0024 T 09-03-2017 UA74_RS05610 9642803628529b38e151672264a90cad 477 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 1 476 4.2E-183 T 09-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 UA74_RS05610 9642803628529b38e151672264a90cad 477 SUPERFAMILY SSF51905 1 261 1.58E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05610 9642803628529b38e151672264a90cad 477 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 1 471 42.187 T 09-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 UA74_RS05610 9642803628529b38e151672264a90cad 477 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 1 476 7.2E-187 T 09-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 UA74_RS05610 9642803628529b38e151672264a90cad 477 Gene3D G3DSA:3.50.50.60 137 264 1.2E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05610 9642803628529b38e151672264a90cad 477 Gene3D G3DSA:3.50.50.60 1 62 1.2E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS28555 fddf509f9c0fd906d97961920dff7f70 197 SUPERFAMILY SSF46689 3 76 1.15E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS28555 fddf509f9c0fd906d97961920dff7f70 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS28555 fddf509f9c0fd906d97961920dff7f70 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS28555 fddf509f9c0fd906d97961920dff7f70 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 51 5.0E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS28555 fddf509f9c0fd906d97961920dff7f70 197 Gene3D G3DSA:1.10.357.10 4 183 1.0E-23 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS19170 1e423b9f94779458fa87eb978b4a42c2 239 Gene3D G3DSA:1.10.150.130 47 138 3.3E-12 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS19170 1e423b9f94779458fa87eb978b4a42c2 239 Gene3D G3DSA:1.10.443.10 151 221 1.5E-5 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS19170 1e423b9f94779458fa87eb978b4a42c2 239 SUPERFAMILY SSF56349 47 209 5.59E-23 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS07650 ed9c5ea00e4d31ad2990126ba9666c5a 469 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 79 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS07650 ed9c5ea00e4d31ad2990126ba9666c5a 469 SUPERFAMILY SSF103473 242 453 4.32E-64 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS07650 ed9c5ea00e4d31ad2990126ba9666c5a 469 SUPERFAMILY SSF103473 3 191 4.32E-64 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS07650 ed9c5ea00e4d31ad2990126ba9666c5a 469 Pfam PF07690 Major Facilitator Superfamily 15 404 2.0E-48 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS07650 ed9c5ea00e4d31ad2990126ba9666c5a 469 Gene3D G3DSA:1.20.1250.20 259 453 4.6E-19 T 09-03-2017 UA74_RS07650 ed9c5ea00e4d31ad2990126ba9666c5a 469 Gene3D G3DSA:1.20.1250.20 9 189 1.4E-26 T 09-03-2017 UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 SUPERFAMILY SSF46785 3 93 1.96E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 Gene3D G3DSA:1.20.120.530 72 210 1.4E-30 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 Pfam PF07729 FCD domain 78 200 8.5E-22 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 SMART SM00345 10 68 1.4E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 SUPERFAMILY SSF48008 74 209 9.15E-28 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 4.2E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 SMART SM00895 78 202 3.6E-16 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 2.9E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 2.9E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS11710 ad4b8bed90dc2d2bc0a68da92143250b 211 Gene3D G3DSA:1.10.10.10 3 68 4.7E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16845 e8eda669ea2dcf7bb0ced094ff6280e9 143 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 16 139 2.9E-24 T 09-03-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_RS16845 e8eda669ea2dcf7bb0ced094ff6280e9 143 Pfam PF14534 Domain of unknown function (DUF4440) 20 132 5.0E-10 T 09-03-2017 IPR027843 Domain of unknown function DUF4440 UA74_RS16845 e8eda669ea2dcf7bb0ced094ff6280e9 143 SUPERFAMILY SSF54427 16 141 2.2E-27 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS16845 e8eda669ea2dcf7bb0ced094ff6280e9 143 Gene3D G3DSA:3.10.450.50 8 141 2.0E-36 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS23370 aa4c1dcce0eb5393a08c1161f4522a0b 146 Pfam PF12728 Helix-turn-helix domain 1 47 1.9E-15 T 09-03-2017 UA74_RS23370 aa4c1dcce0eb5393a08c1161f4522a0b 146 SUPERFAMILY SSF46955 1 47 8.24E-10 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS23370 aa4c1dcce0eb5393a08c1161f4522a0b 146 Gene3D G3DSA:1.10.10.10 2 45 2.0E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23370 aa4c1dcce0eb5393a08c1161f4522a0b 146 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 47 2.2E-13 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_RS20010 fe5f399ebd28a640958e60b46bf49895 657 SUPERFAMILY SSF55874 545 585 3.46E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20010 fe5f399ebd28a640958e60b46bf49895 657 SUPERFAMILY SSF55874 313 385 2.26E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20010 fe5f399ebd28a640958e60b46bf49895 657 Gene3D G3DSA:3.30.565.10 525 588 7.1E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20010 fe5f399ebd28a640958e60b46bf49895 657 Gene3D G3DSA:3.30.565.10 316 386 7.1E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20010 fe5f399ebd28a640958e60b46bf49895 657 Pfam PF07730 Histidine kinase 205 267 1.7E-8 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS02090 eb62d6456eda2cf7d47fec7da5ef7dc7 216 SUPERFAMILY SSF55811 5 155 9.07E-18 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS02090 eb62d6456eda2cf7d47fec7da5ef7dc7 216 Pfam PF00293 NUDIX domain 28 154 2.1E-9 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS02090 eb62d6456eda2cf7d47fec7da5ef7dc7 216 Gene3D G3DSA:3.90.79.10 3 154 8.6E-24 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS08245 cb2ceb00dce66009b331a1584986d805 278 PIRSF PIRSF006648 1 277 7.6E-26 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08245 cb2ceb00dce66009b331a1584986d805 278 Pfam PF01061 ABC-2 type transporter 28 241 2.8E-16 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS08245 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 219 238 9.8E-12 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08245 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 9.8E-12 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08245 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 46 67 9.8E-12 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08245 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 161 185 9.8E-12 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS04265 0d5973caee409331331ff0836da31dba 177 SUPERFAMILY SSF82607 23 112 1.05E-8 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS04265 0d5973caee409331331ff0836da31dba 177 Gene3D G3DSA:3.30.1310.10 21 115 3.6E-11 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS04265 0d5973caee409331331ff0836da31dba 177 Pfam PF02575 YbaB/EbfC DNA-binding family 26 114 8.4E-14 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS13770 a79b8379dde82c198c10d26f6f5ccbf1 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 2.2E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13770 a79b8379dde82c198c10d26f6f5ccbf1 190 SUPERFAMILY SSF48498 81 188 1.26E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS13770 a79b8379dde82c198c10d26f6f5ccbf1 190 Gene3D G3DSA:1.10.357.10 9 187 3.1E-29 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS13770 a79b8379dde82c198c10d26f6f5ccbf1 190 SUPERFAMILY SSF46689 8 86 3.69E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13465 db583f9c04d1807448383137375ab4a7 206 Gene3D G3DSA:3.20.20.70 2 204 4.7E-59 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS13465 db583f9c04d1807448383137375ab4a7 206 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 09-03-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS13465 db583f9c04d1807448383137375ab4a7 206 SUPERFAMILY SSF51569 2 202 1.12E-48 T 09-03-2017 UA74_RS13465 db583f9c04d1807448383137375ab4a7 206 Pfam PF01081 KDPG and KHG aldolase 5 184 1.9E-36 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS04470 c33fd9bc96aa1ed6bd2b2e8e9a906680 145 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 3 140 5.1E-36 T 09-03-2017 IPR032018 Putative lipoprotein, pathogenic bacteria UA74_RS01835 6aff81b529c6fffd47580c801bee0e96 318 Pfam PF11361 Protein of unknown function (DUF3159) 28 212 4.6E-51 T 09-03-2017 IPR016566 Uncharacterised conserved protein UCP010219 UA74_RS08675 aedc9923eb2edd8f93c31ebd1c2c793d 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 20 117 1.7E-19 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 UA74_RS08675 aedc9923eb2edd8f93c31ebd1c2c793d 226 Gene3D G3DSA:1.10.3720.10 17 222 4.1E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08675 aedc9923eb2edd8f93c31ebd1c2c793d 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 222 1.1E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08675 aedc9923eb2edd8f93c31ebd1c2c793d 226 SUPERFAMILY SSF161098 20 214 7.46E-36 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS13370 805d170d248ae1cb6596c06882887fc3 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.6E-5 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13370 805d170d248ae1cb6596c06882887fc3 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 1.6E-5 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13370 805d170d248ae1cb6596c06882887fc3 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 1.6E-5 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13370 805d170d248ae1cb6596c06882887fc3 249 Gene3D G3DSA:3.40.50.1820 1 244 4.1E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS13370 805d170d248ae1cb6596c06882887fc3 249 SUPERFAMILY SSF53474 1 245 1.09E-40 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS13370 805d170d248ae1cb6596c06882887fc3 249 Pfam PF12697 Alpha/beta hydrolase family 14 237 8.4E-21 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13745 1b0530e75b73297c9682fadeebe2f06b 344 SUPERFAMILY SSF53822 41 242 4.12E-6 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS13745 1b0530e75b73297c9682fadeebe2f06b 344 Pfam PF02608 Basic membrane protein 51 304 5.1E-36 T 09-03-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 UA74_RS13745 1b0530e75b73297c9682fadeebe2f06b 344 Gene3D G3DSA:3.40.50.2300 156 300 7.6E-31 T 09-03-2017 UA74_RS13745 1b0530e75b73297c9682fadeebe2f06b 344 Gene3D G3DSA:3.40.50.2300 38 155 5.4E-28 T 09-03-2017 UA74_RS19685 0118395fb8a37fe50e92b0a105b51e8c 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 113 1.6E-4 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS19685 0118395fb8a37fe50e92b0a105b51e8c 119 Gene3D G3DSA:3.10.180.10 2 115 3.7E-11 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS19685 0118395fb8a37fe50e92b0a105b51e8c 119 SUPERFAMILY SSF54593 4 115 6.06E-13 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS13130 c31371497417d363f269a936a45f4a3a 328 SUPERFAMILY SSF51430 1 308 1.01E-97 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS13130 c31371497417d363f269a936a45f4a3a 328 Gene3D G3DSA:3.20.20.100 1 314 2.8E-103 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS13130 c31371497417d363f269a936a45f4a3a 328 Pfam PF00248 Aldo/keto reductase family 16 306 7.4E-71 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS13130 c31371497417d363f269a936a45f4a3a 328 PRINTS PR00069 Aldo-keto reductase signature 43 67 7.7E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS13130 c31371497417d363f269a936a45f4a3a 328 PRINTS PR00069 Aldo-keto reductase signature 140 157 7.7E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS13130 c31371497417d363f269a936a45f4a3a 328 PRINTS PR00069 Aldo-keto reductase signature 109 127 7.7E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 SUPERFAMILY SSF46689 44 92 1.16E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 91 8.5E-6 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 60 75 8.5E-6 T 09-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 SMART SM00342 8 91 3.5E-30 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 SUPERFAMILY SSF46689 1 41 1.3E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 Pfam PF12833 Helix-turn-helix domain 14 92 2.5E-21 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 Gene3D G3DSA:1.10.10.60 1 45 2.6E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 45 87 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_RS17535 78e961f8a619f26426fc270992aeee23 242 Gene3D G3DSA:1.10.10.60 46 92 6.8E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 SUPERFAMILY SSF46689 11 93 3.64E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.5E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.5E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 Gene3D G3DSA:1.10.357.10 69 174 3.3E-20 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 SUPERFAMILY SSF48498 91 148 1.92E-6 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 Gene3D G3DSA:1.10.10.60 12 68 9.5E-23 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS26375 3b01b55b5663196c1bb9541a317eb4cf 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 9.2E-19 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS20550 0f651c749d44395c85b0a9894b417626 328 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 327 2.0E-91 T 09-03-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 UA74_RS20550 0f651c749d44395c85b0a9894b417626 328 SMART SM00829 10 325 7.5E-39 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS20550 0f651c749d44395c85b0a9894b417626 328 SUPERFAMILY SSF51735 119 281 4.43E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20550 0f651c749d44395c85b0a9894b417626 328 Pfam PF00107 Zinc-binding dehydrogenase 153 270 6.6E-22 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS20550 0f651c749d44395c85b0a9894b417626 328 Gene3D G3DSA:3.90.180.10 1 145 1.3E-37 T 09-03-2017 IPR011032 GroES-like UA74_RS20550 0f651c749d44395c85b0a9894b417626 328 SUPERFAMILY SSF50129 1 147 2.83E-32 T 09-03-2017 IPR011032 GroES-like UA74_RS20550 0f651c749d44395c85b0a9894b417626 328 Gene3D G3DSA:3.40.50.720 146 261 1.7E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 Gene3D G3DSA:2.30.38.10 330 408 4.2E-25 T 09-03-2017 UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 Gene3D G3DSA:3.30.300.30 409 509 5.6E-31 T 09-03-2017 UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 Gene3D G3DSA:3.40.50.980 169 329 6.4E-44 T 09-03-2017 UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 Gene3D G3DSA:3.40.50.980 6 168 4.5E-43 T 09-03-2017 UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 SUPERFAMILY SSF56801 4 511 4.32E-157 T 09-03-2017 UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 Pfam PF00501 AMP-binding enzyme 10 414 2.7E-111 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS13640 f02c5a40feaea32729dc409c801413db 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 499 1.8E-18 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS14500 4fcabff1acc098c2cce5149cafc8b998 305 Pfam PF13560 Helix-turn-helix domain 8 87 4.0E-18 T 09-03-2017 UA74_RS14500 4fcabff1acc098c2cce5149cafc8b998 305 Gene3D G3DSA:1.10.260.40 4 83 2.2E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS14500 4fcabff1acc098c2cce5149cafc8b998 305 SUPERFAMILY SSF47413 32 83 5.63E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS14500 4fcabff1acc098c2cce5149cafc8b998 305 SMART SM00530 12 84 1.1E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS06065 7e806f9b117f142335184b93e4c9bd46 290 SUPERFAMILY SSF47413 8 64 2.56E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06065 7e806f9b117f142335184b93e4c9bd46 290 Pfam PF13560 Helix-turn-helix domain 9 70 1.1E-14 T 09-03-2017 UA74_RS06065 7e806f9b117f142335184b93e4c9bd46 290 Gene3D G3DSA:1.10.260.40 6 64 2.1E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06065 7e806f9b117f142335184b93e4c9bd46 290 SMART SM00530 13 68 3.1E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 127 3.4E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 3.4E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 66 77 3.4E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 Gene3D G3DSA:3.40.50.720 3 235 2.3E-77 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 7.9E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 7.9E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 7.9E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 7.9E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 7.9E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 7.9E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 SUPERFAMILY SSF51735 3 235 8.67E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 7 235 2.5E-59 T 09-03-2017 UA74_RS11930 785bb58a07c1e62c06c5b1395c4929ff 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS01020 d2dcb983344772df1f9cf655181b5b0c 564 SUPERFAMILY SSF53850 43 562 1.38E-106 T 09-03-2017 UA74_RS01020 d2dcb983344772df1f9cf655181b5b0c 564 Gene3D G3DSA:3.10.105.10 339 533 1.3E-41 T 09-03-2017 UA74_RS01020 d2dcb983344772df1f9cf655181b5b0c 564 Gene3D G3DSA:3.90.76.10 56 234 3.1E-38 T 09-03-2017 UA74_RS01020 d2dcb983344772df1f9cf655181b5b0c 564 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 479 1.6E-74 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS01020 d2dcb983344772df1f9cf655181b5b0c 564 Gene3D G3DSA:3.40.190.10 235 338 1.7E-30 T 09-03-2017 UA74_RS01020 d2dcb983344772df1f9cf655181b5b0c 564 PIRSF PIRSF002741 5 563 1.8E-92 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS28155 60528d64855eab0743b6a138cbcb4421 355 Pfam PF12697 Alpha/beta hydrolase family 72 331 1.1E-22 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS28155 60528d64855eab0743b6a138cbcb4421 355 SUPERFAMILY SSF53474 47 335 3.89E-52 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS28155 60528d64855eab0743b6a138cbcb4421 355 Gene3D G3DSA:3.40.50.1820 44 339 3.4E-55 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02940 086dd6f7527d8963946f09e21b60b382 99 SUPERFAMILY SSF54189 4 92 2.99E-31 T 09-03-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02940 086dd6f7527d8963946f09e21b60b382 99 Gene3D G3DSA:3.30.70.330 4 95 3.5E-34 T 09-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 UA74_RS02940 086dd6f7527d8963946f09e21b60b382 99 Pfam PF00276 Ribosomal protein L23 7 89 1.0E-31 T 09-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 UA74_RS02940 086dd6f7527d8963946f09e21b60b382 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 6 96 21.369 T 09-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 UA74_RS13055 aec66d4cb7afe09f97fe1ebbaca37c93 385 SUPERFAMILY SSF55920 155 382 9.94E-71 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS13055 aec66d4cb7afe09f97fe1ebbaca37c93 385 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 313 325 - T 09-03-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site UA74_RS13055 aec66d4cb7afe09f97fe1ebbaca37c93 385 Gene3D G3DSA:3.40.350.10 10 154 2.0E-16 T 09-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_RS13055 aec66d4cb7afe09f97fe1ebbaca37c93 385 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 156 6.1E-12 T 09-03-2017 IPR000587 Creatinase, N-terminal GO:0016787 UA74_RS13055 aec66d4cb7afe09f97fe1ebbaca37c93 385 Gene3D G3DSA:3.90.230.10 157 383 8.3E-71 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS13055 aec66d4cb7afe09f97fe1ebbaca37c93 385 Pfam PF00557 Metallopeptidase family M24 165 367 2.3E-59 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS13055 aec66d4cb7afe09f97fe1ebbaca37c93 385 SUPERFAMILY SSF53092 10 154 6.8E-17 T 09-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal UA74_RS07600 d6a402c593176d7d3040e4e15d67df98 147 SMART SM00342 31 114 1.3E-31 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS07600 d6a402c593176d7d3040e4e15d67df98 147 SUPERFAMILY SSF46689 67 115 2.55E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07600 d6a402c593176d7d3040e4e15d67df98 147 Gene3D G3DSA:1.10.10.60 70 116 9.7E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07600 d6a402c593176d7d3040e4e15d67df98 147 SUPERFAMILY SSF46689 15 65 1.88E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07600 d6a402c593176d7d3040e4e15d67df98 147 Gene3D G3DSA:1.10.10.60 15 69 2.3E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07600 d6a402c593176d7d3040e4e15d67df98 147 Pfam PF12833 Helix-turn-helix domain 37 114 4.3E-22 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS13265 c2e34d5c8aeee1ada2163ea147bfd41b 267 Gene3D G3DSA:3.40.50.150 4 267 2.3E-103 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13265 c2e34d5c8aeee1ada2163ea147bfd41b 267 PIRSF PIRSF017393 2 267 5.1E-98 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS13265 c2e34d5c8aeee1ada2163ea147bfd41b 267 Pfam PF04672 S-adenosyl methyltransferase 9 266 3.1E-92 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS13265 c2e34d5c8aeee1ada2163ea147bfd41b 267 SUPERFAMILY SSF53335 10 248 2.82E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 SUPERFAMILY SSF54506 4 135 2.69E-34 T 09-03-2017 UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Gene3D G3DSA:3.10.310.10 4 130 6.4E-38 T 09-03-2017 UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Gene3D G3DSA:3.10.310.10 131 266 2.2E-31 T 09-03-2017 UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 280 9.1E-63 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Pfam PF01678 Diaminopimelate epimerase 6 133 9.7E-33 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Pfam PF01678 Diaminopimelate epimerase 151 274 2.5E-21 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 282 28.998 T 09-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_RS08715 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 SUPERFAMILY SSF54506 141 280 3.14E-28 T 09-03-2017 UA74_RS20500 971c058cf0f9506348d6fb72ad8a5ffe 202 Pfam PF13977 Bacterial transcriptional repressor 82 195 2.8E-26 T 09-03-2017 UA74_RS20500 971c058cf0f9506348d6fb72ad8a5ffe 202 SUPERFAMILY SSF48498 82 195 1.42E-20 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS20500 971c058cf0f9506348d6fb72ad8a5ffe 202 SUPERFAMILY SSF46689 2 77 2.98E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20500 971c058cf0f9506348d6fb72ad8a5ffe 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 5.0E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS20500 971c058cf0f9506348d6fb72ad8a5ffe 202 Gene3D G3DSA:1.10.357.10 1 195 2.2E-45 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 843 876 2.6E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 707 740 0.0045 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 809 842 0.005 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1150 1183 46.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 395 428 6.3E-5 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1048 1081 3.3E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 192 225 370.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 741 774 0.0053 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 673 706 2.3E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 429 462 2.0E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 531 564 10.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 226 259 3.2E-5 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 22 55 0.49 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 158 191 4.7E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 877 910 21.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 328 361 2.9E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 90 123 0.0052 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 463 496 0.009 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 294 327 0.0039 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 497 530 1.6 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 946 979 1.3 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 980 1013 0.001 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1014 1047 0.084 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 571 604 0.0026 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 260 293 34.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 775 808 12.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1082 1115 1.5 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 605 638 0.057 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 639 672 2.3 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 56 89 1.1E-4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 124 157 23.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1116 1149 35.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 650 909 8.35E-37 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 948 1216 1.9E-52 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 390 560 7.3E-42 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 977 1180 7.49E-32 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 11 133 3.1E-26 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 9 360 3.49E-51 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 811 909 9.8E-22 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF00515 Tetratricopeptide repeat 228 257 1.1E-6 T 09-03-2017 IPR001440 Tetratricopeptide repeat 1 GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 814 877 3.2E-7 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 577 637 1.6E-4 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 137 190 0.0048 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 747 806 0.0044 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 8 55 0.011 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 66 122 4.5E-6 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 401 460 1.2E-5 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 301 362 2.7E-7 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 469 525 0.0098 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 644 707 1.1E-9 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 1054 1115 5.3E-4 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 955 1013 0.003 T 09-03-2017 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 401 739 2.28E-43 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 134 372 5.2E-50 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11210 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 573 810 4.9E-50 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS17410 8174a944d29176ccccd4c7e40fbe060b 588 SUPERFAMILY SSF63825 36 193 1.05E-20 T 09-03-2017 UA74_RS17410 8174a944d29176ccccd4c7e40fbe060b 588 Gene3D G3DSA:2.120.10.30 89 305 1.2E-31 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS17410 8174a944d29176ccccd4c7e40fbe060b 588 Gene3D G3DSA:2.120.10.30 376 580 1.9E-24 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS17410 8174a944d29176ccccd4c7e40fbe060b 588 SUPERFAMILY SSF101898 141 304 2.25E-22 T 09-03-2017 UA74_RS17410 8174a944d29176ccccd4c7e40fbe060b 588 SUPERFAMILY SSF63829 376 580 2.78E-28 T 09-03-2017 UA74_RS17410 8174a944d29176ccccd4c7e40fbe060b 588 Gene3D G3DSA:2.120.10.30 34 88 1.1E-9 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS17410 8174a944d29176ccccd4c7e40fbe060b 588 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 379 581 1.0E-7 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 10 293 6.4E-98 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 116 143 1.4E-57 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 10 36 1.4E-57 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 94 116 1.4E-57 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 42 54 1.4E-57 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 267 292 1.4E-57 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 245 267 1.4E-57 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 5 293 46.413 T 09-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 PIRSF PIRSF036480 5 293 1.2E-105 T 09-03-2017 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 Gene3D G3DSA:3.30.70.260 5 79 5.4E-19 T 09-03-2017 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 Pfam PF00551 Formyl transferase 94 273 1.7E-37 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 SUPERFAMILY SSF55021 7 84 2.04E-13 T 09-03-2017 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 SUPERFAMILY SSF53328 94 293 8.77E-56 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS02130 5e2cfe5eedd5e9b8261fd3197a7af2ba 293 Gene3D G3DSA:3.40.50.170 93 290 2.3E-51 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 Gene3D G3DSA:3.40.190.10 111 211 3.6E-27 T 09-03-2017 UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 SMART SM00062 32 251 2.1E-57 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 249 9.2E-59 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 SUPERFAMILY SSF53850 27 249 4.72E-62 T 09-03-2017 UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 SMART SM00079 32 250 1.9E-4 T 09-03-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 54 67 - T 09-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 Gene3D G3DSA:3.40.190.10 212 250 5.5E-36 T 09-03-2017 UA74_RS30070 be23188a17394f2f09ecd5b1a2497192 287 Gene3D G3DSA:3.40.190.10 30 110 5.5E-36 T 09-03-2017 UA74_RS06290 51a3c26f22268642628607fe1aa8bf2e 99 SUPERFAMILY SSF54736 22 97 6.28E-25 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_RS06290 51a3c26f22268642628607fe1aa8bf2e 99 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 93 2.1E-22 T 09-03-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 UA74_RS06290 51a3c26f22268642628607fe1aa8bf2e 99 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 2 99 18.042 T 09-03-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS UA74_RS06290 51a3c26f22268642628607fe1aa8bf2e 99 Gene3D G3DSA:3.30.1390.10 8 98 7.6E-30 T 09-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 Pfam PF07690 Major Facilitator Superfamily 11 420 2.5E-41 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 SUPERFAMILY SSF103473 259 430 1.31E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 SUPERFAMILY SSF103473 487 519 1.31E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 SUPERFAMILY SSF103473 2 188 1.31E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 7 445 4.2E-73 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 Gene3D G3DSA:1.20.1250.20 3 190 3.9E-29 T 09-03-2017 UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 Gene3D G3DSA:1.20.1250.20 282 431 1.2E-10 T 09-03-2017 UA74_RS04350 4a6423cd7ce24929aa9a36d76779e94e 530 Gene3D G3DSA:1.20.1250.20 488 511 1.2E-10 T 09-03-2017 UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 Gene3D G3DSA:2.60.40.360 475 573 4.1E-5 T 09-03-2017 IPR008962 PapD-like UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 Gene3D G3DSA:3.40.50.200 167 469 9.2E-86 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 PRINTS PR00723 Subtilisin serine protease family (S8) signature 238 251 1.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 1.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 1.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 Pfam PF00082 Subtilase family 200 460 1.2E-53 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS03565 7b65cf06a7684065ec4a2a2e37e4dc66 1082 SUPERFAMILY SSF52743 184 469 8.12E-79 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS06455 5983e6d5a0093d10c5056ea276ada565 257 Gene3D G3DSA:3.40.50.300 3 236 7.6E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06455 5983e6d5a0093d10c5056ea276ada565 257 SUPERFAMILY SSF52540 3 231 2.51E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06455 5983e6d5a0093d10c5056ea276ada565 257 SMART SM00382 23 206 4.5E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS06455 5983e6d5a0093d10c5056ea276ada565 257 Pfam PF00005 ABC transporter 15 165 1.3E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04930 414b6039470a90881a6d9a8b8560d1ee 991 Hamap MF_01600 UPF0182 protein . 9 894 18.301 T 09-03-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 UA74_RS04930 414b6039470a90881a6d9a8b8560d1ee 991 Pfam PF03699 Uncharacterised protein family (UPF0182) 18 817 5.7E-279 T 09-03-2017 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 UA74_RS04420 b309516337a651594cfb576541322245 374 SMART SM00382 38 236 7.8E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04420 b309516337a651594cfb576541322245 374 Pfam PF00005 ABC transporter 30 186 3.2E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04420 b309516337a651594cfb576541322245 374 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 302 6.1E-19 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS04420 b309516337a651594cfb576541322245 374 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 321 7.2E-25 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS04420 b309516337a651594cfb576541322245 374 SUPERFAMILY SSF52540 37 311 3.82E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04420 b309516337a651594cfb576541322245 374 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS04420 b309516337a651594cfb576541322245 374 Gene3D G3DSA:3.40.50.300 8 260 1.3E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26500 e517973d46bdb1b84115b3ddfcb671fa 450 Gene3D G3DSA:3.20.20.140 56 387 2.4E-77 T 09-03-2017 UA74_RS26500 e517973d46bdb1b84115b3ddfcb671fa 450 SUPERFAMILY SSF51556 53 376 8.81E-64 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS26500 e517973d46bdb1b84115b3ddfcb671fa 450 Gene3D G3DSA:2.30.40.10 32 38 2.0E-4 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS26500 e517973d46bdb1b84115b3ddfcb671fa 450 Gene3D G3DSA:2.30.40.10 388 428 2.0E-4 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS26500 e517973d46bdb1b84115b3ddfcb671fa 450 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 17 447 7.0E-134 T 09-03-2017 IPR010252 Formiminoglutamate deiminase UA74_RS26500 e517973d46bdb1b84115b3ddfcb671fa 450 Pfam PF01979 Amidohydrolase family 51 424 2.5E-40 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS26500 e517973d46bdb1b84115b3ddfcb671fa 450 SUPERFAMILY SSF51338 356 450 4.32E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17370 559a7edbf94bba04ad2dbb66f0314c57 277 SUPERFAMILY SSF47413 31 80 4.15E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17370 559a7edbf94bba04ad2dbb66f0314c57 277 Pfam PF13560 Helix-turn-helix domain 6 86 2.9E-16 T 09-03-2017 UA74_RS17370 559a7edbf94bba04ad2dbb66f0314c57 277 SMART SM00530 10 83 1.1E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS17370 559a7edbf94bba04ad2dbb66f0314c57 277 Gene3D G3DSA:1.10.260.40 6 80 1.9E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 Pfam PF01494 FAD binding domain 6 363 1.2E-103 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 SUPERFAMILY SSF51905 285 374 2.44E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 SUPERFAMILY SSF51905 6 188 2.44E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 Gene3D G3DSA:3.50.50.60 308 336 1.8E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 Gene3D G3DSA:3.50.50.60 7 191 1.8E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.1E-46 T 09-03-2017 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 1.1E-46 T 09-03-2017 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 1.1E-46 T 09-03-2017 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 349 365 1.1E-46 T 09-03-2017 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 1.1E-46 T 09-03-2017 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 349 1.1E-46 T 09-03-2017 UA74_RS10990 32877ccd882c649093b1a70088a68573 541 Gene3D G3DSA:3.30.9.10 250 307 7.6E-5 T 09-03-2017 UA74_RS29225 b057368a6b046883d25682d2d6066403 230 Gene3D G3DSA:2.60.40.200 113 228 5.1E-11 T 09-03-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS29225 b057368a6b046883d25682d2d6066403 230 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 113 226 2.3E-7 T 09-03-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS29225 b057368a6b046883d25682d2d6066403 230 SUPERFAMILY SSF49329 106 227 3.66E-13 T 09-03-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS29865 8bd3ea17089d20df5d3766d42cde7d07 142 SUPERFAMILY SSF46955 18 103 4.58E-18 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS29865 8bd3ea17089d20df5d3766d42cde7d07 142 Pfam PF13411 MerR HTH family regulatory protein 19 84 1.5E-15 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS29865 8bd3ea17089d20df5d3766d42cde7d07 142 Gene3D G3DSA:1.10.1660.10 19 106 8.5E-21 T 09-03-2017 UA74_RS29865 8bd3ea17089d20df5d3766d42cde7d07 142 ProSitePatterns PS00552 MerR-type HTH domain signature. 20 42 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS29865 8bd3ea17089d20df5d3766d42cde7d07 142 SMART SM00422 17 86 4.1E-23 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 85 674 5.8E-167 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 103 672 3.3E-171 T 09-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 SUPERFAMILY SSF56784 422 670 7.15E-59 T 09-03-2017 IPR023214 HAD-like domain UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 SUPERFAMILY SSF56784 365 384 7.15E-59 T 09-03-2017 IPR023214 HAD-like domain UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 Gene3D G3DSA:3.40.50.1000 493 633 1.4E-51 T 09-03-2017 IPR023214 HAD-like domain UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 Gene3D G3DSA:3.40.50.1000 340 380 1.4E-51 T 09-03-2017 IPR023214 HAD-like domain UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 Gene3D G3DSA:3.40.1110.10 381 492 4.6E-27 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 368 374 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 SUPERFAMILY SSF81653 175 267 3.92E-24 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 139 643 2.0E-83 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 SUPERFAMILY SSF81665 104 170 1.83E-10 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 SUPERFAMILY SSF81665 268 359 1.83E-10 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 Pfam PF00702 haloacid dehalogenase-like hydrolase 362 579 6.9E-47 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 Gene3D G3DSA:2.70.150.10 114 268 3.1E-25 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 Pfam PF00122 E1-E2 ATPase 137 357 3.2E-54 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 366 380 5.9E-29 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 217 231 5.9E-29 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 588 600 5.9E-29 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 522 5.9E-29 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 584 5.9E-29 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 490 501 5.9E-29 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00943 Copper-transporting ATPase signature 638 652 2.7E-8 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00943 Copper-transporting ATPase signature 88 107 2.7E-8 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00943 Copper-transporting ATPase signature 542 559 2.7E-8 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00943 Copper-transporting ATPase signature 156 174 2.7E-8 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00943 Copper-transporting ATPase signature 290 304 2.7E-8 T 09-03-2017 UA74_RS05965 851f5ab8f818fa4ffdedb25106685d63 685 PRINTS PR00943 Copper-transporting ATPase signature 349 364 2.7E-8 T 09-03-2017 UA74_RS12265 f0f0484b733f2d4f97f43f55fe369141 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 130 8.9E-40 T 09-03-2017 IPR011605 NusB antitermination factor GO:0006353 UA74_RS12265 f0f0484b733f2d4f97f43f55fe369141 139 Pfam PF01029 NusB family 6 130 1.2E-34 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_RS12265 f0f0484b733f2d4f97f43f55fe369141 139 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 133 22.277 T 09-03-2017 IPR011605 NusB antitermination factor GO:0006353 UA74_RS12265 f0f0484b733f2d4f97f43f55fe369141 139 SUPERFAMILY SSF48013 3 130 2.09E-38 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_RS12265 f0f0484b733f2d4f97f43f55fe369141 139 Gene3D G3DSA:1.10.940.10 1 130 7.3E-43 T 09-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 Pfam PF00072 Response regulator receiver domain 5 115 4.2E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 SUPERFAMILY SSF52172 1 134 1.22E-34 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 Gene3D G3DSA:1.10.10.10 146 204 5.1E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.3E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.3E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.3E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 SMART SM00448 2 115 6.8E-31 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 SMART SM00421 142 199 1.8E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 SUPERFAMILY SSF46894 133 204 1.63E-18 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 Gene3D G3DSA:3.40.50.2300 1 145 1.9E-40 T 09-03-2017 UA74_RS05315 329e2caf3584e627c4b8847a83f51175 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 196 8.7E-16 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS03335 749807f959cbf604ff8a8e9961e04272 337 SUPERFAMILY SSF46785 10 67 2.12E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03335 749807f959cbf604ff8a8e9961e04272 337 Pfam PF13280 WYL domain 146 316 2.7E-34 T 09-03-2017 IPR026881 WYL domain UA74_RS03335 749807f959cbf604ff8a8e9961e04272 337 Pfam PF08279 HTH domain 12 67 8.4E-12 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS03335 749807f959cbf604ff8a8e9961e04272 337 Gene3D G3DSA:1.10.10.10 9 70 1.8E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 104 117 3.9E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 238 260 3.9E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 46 61 3.9E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 26 44 3.9E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 Pfam PF00561 alpha/beta hydrolase fold 20 249 4.7E-23 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 SUPERFAMILY SSF53474 1 258 6.11E-67 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 2.3E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.3E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.3E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 2.3E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS13540 f5ba0b424d7394ef7965b6d9ba4bb76f 272 Gene3D G3DSA:3.40.50.1820 2 258 2.1E-65 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 4.6E-114 T 09-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Gene3D G3DSA:3.30.1360.10 7 61 6.2E-11 T 09-03-2017 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Gene3D G3DSA:3.30.1360.10 171 217 1.5E-5 T 09-03-2017 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.1E-19 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.6E-25 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 SUPERFAMILY SSF55257 170 220 1.24E-25 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 SUPERFAMILY SSF55257 8 48 1.24E-25 T 09-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 34.804 T 09-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Gene3D G3DSA:1.10.150.20 246 318 1.4E-31 T 09-03-2017 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 SUPERFAMILY SSF56553 48 169 4.71E-43 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 SUPERFAMILY SSF47789 246 318 1.02E-23 T 09-03-2017 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 320 2.0E-24 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 302 8.3E-26 T 09-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 SMART SM00662 18 225 5.5E-97 T 09-03-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS03135 8b20bb46e53a47ac69536246b5802a4a 352 Gene3D G3DSA:2.170.120.12 62 168 1.1E-46 T 09-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS00265 ab1c61d73d85d49aee1d4e08822bce4a 570 Pfam PF13482 RNase_H superfamily 471 556 7.5E-11 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS00265 ab1c61d73d85d49aee1d4e08822bce4a 570 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 239 556 3.1E-52 T 09-03-2017 IPR019993 RecB family nuclease, TM0106, putative UA74_RS00265 ab1c61d73d85d49aee1d4e08822bce4a 570 SUPERFAMILY SSF53098 475 562 1.77E-5 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 SUPERFAMILY SSF48264 13 435 4.45E-92 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 Pfam PF00067 Cytochrome P450 18 411 1.3E-63 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 375 384 6.5E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 298 309 6.5E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 384 395 6.5E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 246 263 6.5E-11 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 374 384 1.1E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 235 252 1.1E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 384 407 1.1E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 337 361 1.1E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 255 281 1.1E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 24 43 1.1E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 Gene3D G3DSA:1.10.630.10 13 435 1.2E-95 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24185 54608386d84ef399fd0c9f5802c921b1 436 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 377 386 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS04300 70fee588caca1ce341cda7837e231ece 99 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 93 20.448 T 09-03-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 UA74_RS04300 70fee588caca1ce341cda7837e231ece 99 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 91 2.0E-25 T 09-03-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 UA74_RS04300 70fee588caca1ce341cda7837e231ece 99 SUPERFAMILY SSF55248 1 94 1.44E-27 T 09-03-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 UA74_RS04300 70fee588caca1ce341cda7837e231ece 99 Gene3D G3DSA:3.30.1360.20 2 93 8.0E-27 T 09-03-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 UA74_RS22250 8c44668b919c48f27b431d6101b7a405 396 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 129 1.2E-20 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS22250 8c44668b919c48f27b431d6101b7a405 396 Gene3D G3DSA:3.40.50.720 7 145 6.2E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22250 8c44668b919c48f27b431d6101b7a405 396 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 212 4.0E-8 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS22250 8c44668b919c48f27b431d6101b7a405 396 SUPERFAMILY SSF55347 135 321 4.41E-25 T 09-03-2017 UA74_RS22250 8c44668b919c48f27b431d6101b7a405 396 SUPERFAMILY SSF51735 5 160 9.86E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22250 8c44668b919c48f27b431d6101b7a405 396 Gene3D G3DSA:3.30.360.10 146 373 9.5E-36 T 09-03-2017 UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 Gene3D G3DSA:2.40.10.10 163 260 1.1E-9 T 09-03-2017 UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 Gene3D G3DSA:3.30.300.50 5 84 2.4E-16 T 09-03-2017 UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 Pfam PF02983 Alpha-lytic protease prodomain 88 144 5.9E-5 T 09-03-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 SUPERFAMILY SSF50494 178 347 7.11E-23 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 319 330 - T 09-03-2017 IPR033116 Serine proteases, trypsin family, serine active site UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 Gene3D G3DSA:2.40.10.10 261 353 4.5E-15 T 09-03-2017 UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 Gene3D G3DSA:2.60.40.1560 391 440 9.8E-5 T 09-03-2017 UA74_RS29885 aace700b477f8a79a79aeff30b09ed7a 638 Gene3D G3DSA:2.60.40.1560 482 549 5.0E-5 T 09-03-2017 UA74_RS02400 9a2dc2b6920b9fa65010ad565fbc0a9a 77 Gene3D G3DSA:1.10.1660.10 17 62 4.7E-6 T 09-03-2017 UA74_RS02400 9a2dc2b6920b9fa65010ad565fbc0a9a 77 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 64 1.4E-10 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_RS02400 9a2dc2b6920b9fa65010ad565fbc0a9a 77 SUPERFAMILY SSF46955 15 66 5.95E-11 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS02400 9a2dc2b6920b9fa65010ad565fbc0a9a 77 Pfam PF12728 Helix-turn-helix domain 16 64 1.1E-10 T 09-03-2017 UA74_RS07245 6c5713049c8be7e126e1673daa075b92 219 Pfam PF01939 Protein of unknown function DUF91 1 219 8.2E-82 T 09-03-2017 IPR002793 Endonuclease NucS UA74_RS07245 6c5713049c8be7e126e1673daa075b92 219 Hamap MF_00722 Endonuclease NucS [nucS]. 1 211 31.168 T 09-03-2017 IPR002793 Endonuclease NucS UA74_RS27125 6b5ce0c8a267d2701259ef943c818298 295 SUPERFAMILY SSF53850 92 284 4.5E-32 T 09-03-2017 UA74_RS27125 6b5ce0c8a267d2701259ef943c818298 295 Pfam PF03466 LysR substrate binding domain 90 284 4.0E-37 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS27125 6b5ce0c8a267d2701259ef943c818298 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.4E-18 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS27125 6b5ce0c8a267d2701259ef943c818298 295 SUPERFAMILY SSF46785 2 109 3.78E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27125 6b5ce0c8a267d2701259ef943c818298 295 Gene3D G3DSA:3.40.190.10 182 270 2.3E-25 T 09-03-2017 UA74_RS27125 6b5ce0c8a267d2701259ef943c818298 295 Gene3D G3DSA:1.10.10.10 3 89 5.4E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27125 6b5ce0c8a267d2701259ef943c818298 295 Gene3D G3DSA:3.40.190.10 92 181 3.5E-19 T 09-03-2017 UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 SUPERFAMILY SSF56784 16 235 1.63E-46 T 09-03-2017 IPR023214 HAD-like domain UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 208 4.2E-21 T 09-03-2017 IPR023214 HAD-like domain UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 123 203 1.9E-12 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 208 2.4E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 Gene3D G3DSA:3.40.50.1000 16 233 4.1E-43 T 09-03-2017 IPR023214 HAD-like domain UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 16 27 3.7E-15 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 168 3.7E-15 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 170 190 3.7E-15 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS26065 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 121 134 3.7E-15 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 305 312 - T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 134 341 6.1E-76 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 558 575 - T 09-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF51246 348 467 7.85E-37 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Pfam PF00364 Biotin-requiring enzyme 536 601 2.9E-16 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Gene3D G3DSA:3.30.470.20 223 467 7.9E-90 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Pfam PF02785 Biotin carboxylase C-terminal domain 354 463 6.8E-36 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Pfam PF00289 Biotin carboxylase, N-terminal domain 21 129 2.7E-43 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF51230 532 601 9.29E-19 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Gene3D G3DSA:3.30.1490.20 149 221 3.2E-22 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Gene3D G3DSA:3.40.50.20 21 148 1.9E-46 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 Gene3D G3DSA:2.40.50.100 534 602 2.1E-21 T 09-03-2017 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF56059 102 342 1.33E-58 T 09-03-2017 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 SMART SM00878 354 463 4.1E-57 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS27145 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF52440 18 132 8.63E-47 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 SUPERFAMILY SSF53067 150 384 2.13E-63 T 09-03-2017 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 SUPERFAMILY SSF53067 18 186 1.62E-42 T 09-03-2017 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 193 210 - T 09-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 Gene3D G3DSA:3.30.420.40 196 383 7.0E-57 T 09-03-2017 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 PIRSF PIRSF000722 46 387 1.8E-98 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 165 178 9.8E-32 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 193 214 9.8E-32 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 366 378 9.8E-32 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 314 330 9.8E-32 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 20 31 9.8E-32 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 292 305 9.8E-32 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 Hamap MF_00020 Acetate kinase [ackA]. 1 387 116.257 T 09-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 Pfam PF00871 Acetokinase family 54 378 6.3E-85 T 09-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 Gene3D G3DSA:3.30.420.40 19 195 1.5E-7 T 09-03-2017 UA74_RS11845 6681461eb2714bcb1ce70c602dd94a38 387 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 20 31 - T 09-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_RS03020 230dfc7ebf5e85adbd28b503cd519d3f 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 09-03-2017 IPR018038 Ribosomal protein L30, conserved site UA74_RS03020 230dfc7ebf5e85adbd28b503cd519d3f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.081 T 09-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 UA74_RS03020 230dfc7ebf5e85adbd28b503cd519d3f 60 Gene3D G3DSA:3.30.1390.20 1 59 6.2E-27 T 09-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain UA74_RS03020 230dfc7ebf5e85adbd28b503cd519d3f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 2.6E-23 T 09-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 UA74_RS03020 230dfc7ebf5e85adbd28b503cd519d3f 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 7.1E-18 T 09-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain UA74_RS03020 230dfc7ebf5e85adbd28b503cd519d3f 60 SUPERFAMILY SSF55129 1 60 1.44E-21 T 09-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain UA74_RS03020 230dfc7ebf5e85adbd28b503cd519d3f 60 PIRSF PIRSF002211 1 60 3.6E-28 T 09-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 UA74_RS14445 9e24f82d7f49d93f26ed1ebf7c3d4a3e 622 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 20 155 4.2E-17 T 09-03-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 UA74_RS14445 9e24f82d7f49d93f26ed1ebf7c3d4a3e 622 Gene3D G3DSA:3.30.379.10 17 155 3.3E-15 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS14445 9e24f82d7f49d93f26ed1ebf7c3d4a3e 622 Pfam PF07555 beta-N-acetylglucosaminidase 162 473 1.7E-107 T 09-03-2017 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 UA74_RS14445 9e24f82d7f49d93f26ed1ebf7c3d4a3e 622 SUPERFAMILY SSF140657 490 619 2.17E-5 T 09-03-2017 UA74_RS14445 9e24f82d7f49d93f26ed1ebf7c3d4a3e 622 SUPERFAMILY SSF51445 160 487 1.01E-103 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS14445 9e24f82d7f49d93f26ed1ebf7c3d4a3e 622 SUPERFAMILY SSF55545 19 157 1.1E-16 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 Pfam PF13411 MerR HTH family regulatory protein 2 71 1.8E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 Gene3D G3DSA:3.20.80.10 124 270 1.0E-6 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 SMART SM00422 2 72 5.1E-20 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 SMART SM00871 119 271 6.9E-13 T 09-03-2017 IPR010499 Bacterial transcription activator, effector binding UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 Gene3D G3DSA:1.10.1660.10 2 111 1.0E-24 T 09-03-2017 UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 SUPERFAMILY SSF55136 121 270 1.4E-18 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 SUPERFAMILY SSF46955 2 111 1.98E-23 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS22535 6816d7de708441a60e3ccf92a1842ba4 274 Pfam PF06445 GyrI-like small molecule binding domain 123 267 6.5E-9 T 09-03-2017 IPR029442 GyrI-like small molecule binding domain UA74_RS26280 7d5c26b6f463cc8ebc83074ba9850fe5 171 Pfam PF00583 Acetyltransferase (GNAT) family 65 146 2.8E-15 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS26280 7d5c26b6f463cc8ebc83074ba9850fe5 171 SUPERFAMILY SSF55729 10 150 1.36E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS26280 7d5c26b6f463cc8ebc83074ba9850fe5 171 Gene3D G3DSA:3.40.630.30 8 167 3.5E-28 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29145 43eba8497b9ebc091c4fa28f041742ba 131 Gene3D G3DSA:1.10.260.40 15 68 1.3E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS26340 eef08ff275ae46697e76aa32b078085c 148 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 3 77 2.7E-9 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS26340 eef08ff275ae46697e76aa32b078085c 148 SUPERFAMILY SSF50475 2 96 7.05E-14 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS26340 eef08ff275ae46697e76aa32b078085c 148 Gene3D G3DSA:2.30.110.10 6 99 3.9E-16 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS21855 3925a8226cb0fa4f33bf2cdd8b75b033 193 Pfam PF13302 Acetyltransferase (GNAT) domain 9 146 7.3E-26 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS21855 3925a8226cb0fa4f33bf2cdd8b75b033 193 SUPERFAMILY SSF55729 3 170 9.33E-42 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS21855 3925a8226cb0fa4f33bf2cdd8b75b033 193 Gene3D G3DSA:3.40.630.30 3 175 3.1E-45 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS17510 d1ffb2d2e055878025ec3ef87586f4a9 406 Gene3D G3DSA:3.40.50.150 97 248 2.5E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17510 d1ffb2d2e055878025ec3ef87586f4a9 406 Pfam PF08484 C-methyltransferase C-terminal domain 244 401 4.1E-54 T 09-03-2017 IPR013691 C-methyltransferase UA74_RS17510 d1ffb2d2e055878025ec3ef87586f4a9 406 Pfam PF13489 Methyltransferase domain 80 239 2.7E-13 T 09-03-2017 UA74_RS17510 d1ffb2d2e055878025ec3ef87586f4a9 406 SUPERFAMILY SSF53335 71 254 1.13E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17510 d1ffb2d2e055878025ec3ef87586f4a9 406 Pfam PF08421 Putative zinc binding domain 5 63 2.6E-14 T 09-03-2017 IPR013630 Methyltransferase putative zinc binding domain UA74_RS22960 8d02b7b5475e3cd8fb516c9e068784ba 233 SUPERFAMILY SSF48498 79 222 1.56E-24 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS22960 8d02b7b5475e3cd8fb516c9e068784ba 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 5.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22960 8d02b7b5475e3cd8fb516c9e068784ba 233 SUPERFAMILY SSF46689 9 70 3.39E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22960 8d02b7b5475e3cd8fb516c9e068784ba 233 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 221 1.0E-18 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS22960 8d02b7b5475e3cd8fb516c9e068784ba 233 Gene3D G3DSA:1.10.357.10 3 224 2.2E-53 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS27700 81b7c6d85161e47a1c5c6d2dd104587e 463 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 99 322 5.6E-28 T 09-03-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 UA74_RS27700 81b7c6d85161e47a1c5c6d2dd104587e 463 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 209 222 2.1E-7 T 09-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UA74_RS27700 81b7c6d85161e47a1c5c6d2dd104587e 463 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 183 200 2.1E-7 T 09-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UA74_RS27700 81b7c6d85161e47a1c5c6d2dd104587e 463 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 146 2.1E-7 T 09-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UA74_RS27700 81b7c6d85161e47a1c5c6d2dd104587e 463 Gene3D G3DSA:3.40.710.10 102 342 3.1E-58 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS27700 81b7c6d85161e47a1c5c6d2dd104587e 463 SUPERFAMILY SSF56601 98 342 1.11E-46 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS13470 dec9631991eabd9efe736e3ba90057ab 314 SUPERFAMILY SSF53613 1 302 5.61E-72 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS13470 dec9631991eabd9efe736e3ba90057ab 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS13470 dec9631991eabd9efe736e3ba90057ab 314 Gene3D G3DSA:3.40.1190.20 1 302 1.3E-77 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS13470 dec9631991eabd9efe736e3ba90057ab 314 Pfam PF00294 pfkB family carbohydrate kinase 18 298 1.2E-47 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS28140 4bae059b1a3fb8ec7c71306f5a3ac48d 268 SUPERFAMILY SSF55781 76 259 1.31E-45 T 09-03-2017 IPR029016 GAF domain-like UA74_RS28140 4bae059b1a3fb8ec7c71306f5a3ac48d 268 SMART SM00346 19 106 2.0E-24 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS28140 4bae059b1a3fb8ec7c71306f5a3ac48d 268 Pfam PF01614 Bacterial transcriptional regulator 134 255 2.0E-30 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS28140 4bae059b1a3fb8ec7c71306f5a3ac48d 268 Gene3D G3DSA:3.30.450.40 93 259 1.6E-56 T 09-03-2017 IPR029016 GAF domain-like UA74_RS28140 4bae059b1a3fb8ec7c71306f5a3ac48d 268 Pfam PF09339 IclR helix-turn-helix domain 21 72 7.6E-20 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS28140 4bae059b1a3fb8ec7c71306f5a3ac48d 268 SUPERFAMILY SSF46785 19 89 6.04E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28140 4bae059b1a3fb8ec7c71306f5a3ac48d 268 Gene3D G3DSA:1.10.10.10 17 90 5.9E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22565 af23f8bd35aab1210e42a5fa78fe71ba 316 Gene3D G3DSA:1.10.3720.10 86 310 7.8E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22565 af23f8bd35aab1210e42a5fa78fe71ba 316 SUPERFAMILY SSF161098 89 296 1.26E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22565 af23f8bd35aab1210e42a5fa78fe71ba 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.9E-35 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS02715 6ccb8b14015f5a6132e7e8a77a26360a 181 Pfam PF13521 AAA domain 9 172 1.4E-40 T 09-03-2017 UA74_RS02715 6ccb8b14015f5a6132e7e8a77a26360a 181 Gene3D G3DSA:3.40.50.300 7 176 1.2E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02715 6ccb8b14015f5a6132e7e8a77a26360a 181 SUPERFAMILY SSF52540 6 178 4.71E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24020 e88f8e55021daba0d8eb0ce359e04d9e 438 SMART SM00479 5 171 2.0E-27 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS24020 e88f8e55021daba0d8eb0ce359e04d9e 438 SUPERFAMILY SSF52113 351 420 1.24E-7 T 09-03-2017 IPR001357 BRCT domain UA74_RS24020 e88f8e55021daba0d8eb0ce359e04d9e 438 Gene3D G3DSA:3.30.420.10 5 168 6.7E-47 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS24020 e88f8e55021daba0d8eb0ce359e04d9e 438 Gene3D G3DSA:3.40.50.10190 350 425 1.9E-9 T 09-03-2017 IPR001357 BRCT domain UA74_RS24020 e88f8e55021daba0d8eb0ce359e04d9e 438 SUPERFAMILY SSF53098 5 168 1.41E-44 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS24020 e88f8e55021daba0d8eb0ce359e04d9e 438 Pfam PF00929 Exonuclease 8 161 7.0E-21 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS21570 ae6a946e91ea8957eaa40c582a71eee9 162 Pfam PF08044 Domain of unknown function (DUF1707) 11 62 2.2E-17 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS21570 ae6a946e91ea8957eaa40c582a71eee9 162 Pfam PF05154 TM2 domain 95 145 8.6E-11 T 09-03-2017 IPR007829 TM2 domain UA74_RS22185 8f62777110e98c1bab7d1a6436aef0c0 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.1E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22185 8f62777110e98c1bab7d1a6436aef0c0 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.1E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22185 8f62777110e98c1bab7d1a6436aef0c0 188 Gene3D G3DSA:1.10.357.10 13 182 9.1E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22185 8f62777110e98c1bab7d1a6436aef0c0 188 SUPERFAMILY SSF48498 102 182 1.46E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS22185 8f62777110e98c1bab7d1a6436aef0c0 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 6.0E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22185 8f62777110e98c1bab7d1a6436aef0c0 188 SUPERFAMILY SSF46689 5 84 3.04E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 Pfam PF00664 ABC transporter transmembrane region 56 326 2.1E-38 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 Gene3D G3DSA:3.40.50.300 374 628 2.3E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 SMART SM00382 423 609 2.0E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 SUPERFAMILY SSF52540 371 631 4.28E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 ProSitePatterns PS00211 ABC transporters family signature. 535 549 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 Gene3D G3DSA:1.20.1560.10 44 360 1.1E-65 T 09-03-2017 UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 Pfam PF00005 ABC transporter 414 562 2.6E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS28460 5359b0d1f0d4a663ab317dc1731aa40d 710 SUPERFAMILY SSF90123 44 352 4.45E-66 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 Pfam PF00664 ABC transporter transmembrane region 170 431 3.0E-28 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 Gene3D G3DSA:1.20.1560.10 155 464 2.6E-55 T 09-03-2017 UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 Gene3D G3DSA:3.90.70.10 18 137 5.8E-16 T 09-03-2017 UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 Pfam PF00005 ABC transporter 497 646 8.8E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 SUPERFAMILY SSF90123 152 465 1.7E-54 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 Gene3D G3DSA:3.40.50.300 479 707 1.1E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 SMART SM00382 506 696 9.3E-19 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 ProSitePatterns PS00211 ABC transporters family signature. 618 632 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 SUPERFAMILY SSF52540 473 714 1.33E-80 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09515 30e79a118c12a3fd7a641e28caebcba2 717 Pfam PF03412 Peptidase C39 family 11 138 3.9E-33 T 09-03-2017 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 Gene3D G3DSA:1.10.580.10 57 286 1.9E-95 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 246 274 1.5E-53 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 302 322 1.5E-53 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 385 399 1.5E-53 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 365 381 1.5E-53 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 170 183 1.5E-53 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 224 239 1.5E-53 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 20 428 8.5E-183 T 09-03-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 SUPERFAMILY SSF48256 12 434 7.85E-159 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 PIRSF PIRSF001369 42 434 3.5E-156 T 09-03-2017 IPR024176 Citrate synthase, bacterial-type UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 Gene3D G3DSA:1.10.230.10 287 379 1.6E-36 T 09-03-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 Pfam PF00285 Citrate synthase, C-terminal domain 51 417 6.1E-134 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS28400 1cd84e31e6910e062529d26bf525903f 434 ProSitePatterns PS00480 Citrate synthase signature. 309 321 - T 09-03-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS16630 744fa72bc7a6cdc96fd35a955ceb3337 252 SUPERFAMILY SSF53335 8 158 2.07E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16630 744fa72bc7a6cdc96fd35a955ceb3337 252 Gene3D G3DSA:3.40.50.150 25 157 4.5E-10 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS18385 043bae096304272077346d7506d9e6c3 361 Gene3D G3DSA:3.40.50.2300 197 353 1.6E-43 T 09-03-2017 UA74_RS18385 043bae096304272077346d7506d9e6c3 361 Gene3D G3DSA:3.40.50.2300 85 196 1.1E-26 T 09-03-2017 UA74_RS18385 043bae096304272077346d7506d9e6c3 361 Pfam PF13407 Periplasmic binding protein domain 75 335 3.0E-53 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS18385 043bae096304272077346d7506d9e6c3 361 SUPERFAMILY SSF53822 73 354 3.61E-68 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS25875 fc5c7ec9fda590a55efe468fb8354d08 293 Pfam PF00892 EamA-like transporter family 151 285 5.2E-16 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS25875 fc5c7ec9fda590a55efe468fb8354d08 293 Pfam PF00892 EamA-like transporter family 6 140 1.4E-20 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS25875 fc5c7ec9fda590a55efe468fb8354d08 293 SUPERFAMILY SSF103481 41 143 2.88E-10 T 09-03-2017 UA74_RS25875 fc5c7ec9fda590a55efe468fb8354d08 293 SUPERFAMILY SSF103481 213 289 5.36E-10 T 09-03-2017 UA74_RS07205 2f75fc6255cad03781ee4b760c17a71f 191 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 185 2.0E-49 T 09-03-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_RS07205 2f75fc6255cad03781ee4b760c17a71f 191 SUPERFAMILY SSF89028 6 183 3.73E-56 T 09-03-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_RS07205 2f75fc6255cad03781ee4b760c17a71f 191 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 181 7.2E-52 T 09-03-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_RS07205 2f75fc6255cad03781ee4b760c17a71f 191 Pfam PF01923 Cobalamin adenosyltransferase 8 176 1.4E-57 T 09-03-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_RS07205 2f75fc6255cad03781ee4b760c17a71f 191 Gene3D G3DSA:1.20.1200.10 17 189 1.1E-58 T 09-03-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_RS29140 c00ca9483bfc019c0580aafce07a20dc 389 SUPERFAMILY SSF48452 165 366 2.1E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS29140 c00ca9483bfc019c0580aafce07a20dc 389 Gene3D G3DSA:1.25.40.10 161 374 4.5E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS28440 d8597eca4d7b066c8468b98b1b622c74 338 Pfam PF11268 Protein of unknown function (DUF3071) 1 169 9.6E-61 T 09-03-2017 IPR021421 Protein of unknown function DUF3071 UA74_RS11945 bd66b641b831e2cd6f76a5d570d9a1c6 332 SUPERFAMILY SSF51430 5 319 1.18E-63 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS11945 bd66b641b831e2cd6f76a5d570d9a1c6 332 Pfam PF00248 Aldo/keto reductase family 16 317 3.9E-42 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS11945 bd66b641b831e2cd6f76a5d570d9a1c6 332 Gene3D G3DSA:3.20.20.100 4 318 1.3E-55 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS06765 2a24f9661056ecd981a066493f3f3134 217 Gene3D G3DSA:3.30.420.10 2 178 2.8E-70 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS06765 2a24f9661056ecd981a066493f3f3134 217 Pfam PF00929 Exonuclease 6 169 2.9E-30 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS06765 2a24f9661056ecd981a066493f3f3134 217 SUPERFAMILY SSF53098 3 178 5.88E-45 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS06765 2a24f9661056ecd981a066493f3f3134 217 SMART SM00479 4 179 1.3E-30 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS06765 2a24f9661056ecd981a066493f3f3134 217 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 38.926 T 09-03-2017 IPR022894 Oligoribonuclease GO:0016788 UA74_RS27585 c03c022345cb4c0731df2049d512feac 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS27585 c03c022345cb4c0731df2049d512feac 477 Gene3D G3DSA:3.40.605.10 21 270 3.0E-99 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS27585 c03c022345cb4c0731df2049d512feac 477 SUPERFAMILY SSF53720 16 476 1.19E-160 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS27585 c03c022345cb4c0731df2049d512feac 477 Pfam PF00171 Aldehyde dehydrogenase family 30 476 1.3E-162 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS27585 c03c022345cb4c0731df2049d512feac 477 Gene3D G3DSA:3.40.309.10 271 455 3.3E-66 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS17375 ae086e8007abd60c1e1cf4852dc840d1 47 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 1 47 2.8E-22 T 09-03-2017 IPR020955 Uncharacterised protein family Atu4866 UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 Pfam PF05147 Lanthionine synthetase C-like protein 709 1091 7.5E-49 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 SUPERFAMILY SSF158745 683 1093 1.23E-61 T 09-03-2017 UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 158 1083 1.0E-232 T 09-03-2017 IPR017146 Type 2 lantibiotic biosynthesis protein LanM UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 Pfam PF13575 Domain of unknown function (DUF4135) 211 591 8.2E-105 T 09-03-2017 IPR025410 Domain of unknown function DUF4135 UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 PIRSF PIRSF037228 155 1096 3.3E-175 T 09-03-2017 IPR017146 Type 2 lantibiotic biosynthesis protein LanM UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 PRINTS PR01950 LanC-like protein superfamily signature 1063 1080 6.7E-14 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 PRINTS PR01950 LanC-like protein superfamily signature 709 727 6.7E-14 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 PRINTS PR01950 LanC-like protein superfamily signature 881 897 6.7E-14 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 PRINTS PR01950 LanC-like protein superfamily signature 823 838 6.7E-14 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 PRINTS PR01950 LanC-like protein superfamily signature 944 964 6.7E-14 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS09525 a7c79340df1b7964389cd40c73ef1803 1104 SMART SM01260 706 1091 5.3E-56 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS04705 e8c24045fc90bdf84edd3a3d0d634bca 360 SUPERFAMILY SSF144083 295 357 7.32E-19 T 09-03-2017 UA74_RS04705 e8c24045fc90bdf84edd3a3d0d634bca 360 Pfam PF01544 CorA-like Mg2+ transporter protein 63 355 1.5E-59 T 09-03-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 UA74_RS04705 e8c24045fc90bdf84edd3a3d0d634bca 360 Gene3D G3DSA:3.30.460.20 29 169 2.9E-43 T 09-03-2017 UA74_RS04705 e8c24045fc90bdf84edd3a3d0d634bca 360 Gene3D G3DSA:1.20.58.340 284 360 9.6E-25 T 09-03-2017 UA74_RS04705 e8c24045fc90bdf84edd3a3d0d634bca 360 SUPERFAMILY SSF143865 24 292 3.66E-64 T 09-03-2017 UA74_RS04705 e8c24045fc90bdf84edd3a3d0d634bca 360 Gene3D G3DSA:1.20.58.340 170 281 8.4E-36 T 09-03-2017 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 SUPERFAMILY SSF51905 186 398 7.34E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 SUPERFAMILY SSF51905 3 220 1.11E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 330 2.0E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.4E-7 T 09-03-2017 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 197 222 7.4E-7 T 09-03-2017 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 304 320 3.8E-8 T 09-03-2017 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.8E-8 T 09-03-2017 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 197 215 3.8E-8 T 09-03-2017 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 Gene3D G3DSA:3.50.50.60 205 380 2.0E-7 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS19600 e1d5c5634e0a70f6e80e72d830332b20 457 Gene3D G3DSA:3.50.50.60 5 204 1.1E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS01080 8915c1e13db87f76e2a9bbdc6bfa6d24 150 Pfam PF01475 Ferric uptake regulator family 25 114 1.1E-18 T 09-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 UA74_RS01080 8915c1e13db87f76e2a9bbdc6bfa6d24 150 Gene3D G3DSA:1.10.10.10 18 93 4.1E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01080 8915c1e13db87f76e2a9bbdc6bfa6d24 150 SUPERFAMILY SSF46785 18 145 1.21E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04440 70d3d6a38c16dc1bb006acb5f379adb2 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS04440 70d3d6a38c16dc1bb006acb5f379adb2 106 Gene3D G3DSA:3.30.70.20 5 78 1.3E-18 T 09-03-2017 UA74_RS04440 70d3d6a38c16dc1bb006acb5f379adb2 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.7E-17 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 UA74_RS04440 70d3d6a38c16dc1bb006acb5f379adb2 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.7E-17 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 UA74_RS04440 70d3d6a38c16dc1bb006acb5f379adb2 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.7E-17 T 09-03-2017 IPR000813 7Fe ferredoxin GO:0009055 UA74_RS04440 70d3d6a38c16dc1bb006acb5f379adb2 106 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_RS04440 70d3d6a38c16dc1bb006acb5f379adb2 106 SUPERFAMILY SSF54862 3 85 1.08E-20 T 09-03-2017 UA74_RS27945 deff853efd3d798c659833a09a875e15 101 SUPERFAMILY SSF48600 17 79 4.12E-14 T 09-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_RS27945 deff853efd3d798c659833a09a875e15 101 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 20 93 2.6E-30 T 09-03-2017 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal UA74_RS27945 deff853efd3d798c659833a09a875e15 101 Gene3D G3DSA:1.20.59.10 15 82 6.8E-16 T 09-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_RS27945 deff853efd3d798c659833a09a875e15 101 Pfam PF01817 Chorismate mutase type II 25 84 7.6E-11 T 09-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_RS27945 deff853efd3d798c659833a09a875e15 101 SMART SM00830 25 87 7.4E-8 T 09-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_RS27310 988256f1455c0b0cdb27bfad83c3e070 417 Pfam PF09339 IclR helix-turn-helix domain 20 62 3.1E-5 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS27310 988256f1455c0b0cdb27bfad83c3e070 417 Gene3D G3DSA:1.10.10.10 14 82 3.8E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27310 988256f1455c0b0cdb27bfad83c3e070 417 Gene3D G3DSA:3.30.420.40 229 379 5.8E-42 T 09-03-2017 UA74_RS27310 988256f1455c0b0cdb27bfad83c3e070 417 Gene3D G3DSA:3.30.420.40 87 228 5.2E-34 T 09-03-2017 UA74_RS27310 988256f1455c0b0cdb27bfad83c3e070 417 Pfam PF00480 ROK family 88 395 4.0E-46 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS27310 988256f1455c0b0cdb27bfad83c3e070 417 SUPERFAMILY SSF46785 14 75 1.13E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27310 988256f1455c0b0cdb27bfad83c3e070 417 SUPERFAMILY SSF53067 88 399 1.2E-42 T 09-03-2017 UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 Pfam PF00557 Metallopeptidase family M24 13 245 1.9E-43 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 Gene3D G3DSA:3.90.230.10 3 257 3.7E-69 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 SUPERFAMILY SSF55920 2 253 1.23E-69 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 31.863 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 3.5E-70 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 8.2E-17 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 8.2E-17 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 8.2E-17 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS17250 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 8.2E-17 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS24715 1719a34f2005eced67a729307672c189 214 Pfam PF03473 MOSC domain 49 161 1.2E-13 T 09-03-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 UA74_RS24715 1719a34f2005eced67a729307672c189 214 SUPERFAMILY SSF50800 1 209 1.15E-45 T 09-03-2017 IPR011037 Pyruvate kinase-like, insert domain UA74_RS24715 1719a34f2005eced67a729307672c189 214 Gene3D G3DSA:2.40.33.20 1 210 1.4E-56 T 09-03-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like UA74_RS15920 e0253b8b18633c15b38a3271b3271e5f 224 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 6 135 6.7E-12 T 09-03-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_RS15920 e0253b8b18633c15b38a3271b3271e5f 224 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 46 1.4E-8 T 09-03-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_RS08795 822cf3e7993438cb3ba2f8b683d3df75 395 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 229 381 8.8E-23 T 09-03-2017 IPR031475 Putative nucleotide-binding C-terminal domain UA74_RS08795 822cf3e7993438cb3ba2f8b683d3df75 395 SUPERFAMILY SSF142764 5 386 6.15E-85 T 09-03-2017 UA74_RS08795 822cf3e7993438cb3ba2f8b683d3df75 395 Pfam PF07005 Putative sugar-binding N-terminal domain 5 215 1.3E-47 T 09-03-2017 IPR010737 Putative sugar-binding, N-terminal domain UA74_RS29265 6b83218ec99c9ed563f7835e06f7e450 258 SMART SM00382 29 223 7.0E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS29265 6b83218ec99c9ed563f7835e06f7e450 258 Pfam PF00005 ABC transporter 21 176 1.5E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS29265 6b83218ec99c9ed563f7835e06f7e450 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS29265 6b83218ec99c9ed563f7835e06f7e450 258 Gene3D G3DSA:3.40.50.300 3 250 5.8E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29265 6b83218ec99c9ed563f7835e06f7e450 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 5.3E-115 T 09-03-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 UA74_RS29265 6b83218ec99c9ed563f7835e06f7e450 258 SUPERFAMILY SSF52540 5 244 4.73E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21060 21b00ad44b6fff99c7308573f0b1fe8c 217 Gene3D G3DSA:1.10.357.10 28 198 2.5E-24 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS21060 21b00ad44b6fff99c7308573f0b1fe8c 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 83 3.2E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS21060 21b00ad44b6fff99c7308573f0b1fe8c 217 SUPERFAMILY SSF46689 35 103 9.98E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 Gene3D G3DSA:3.30.70.1400 52 136 1.1E-11 T 09-03-2017 UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 SUPERFAMILY SSF103025 12 265 2.2E-46 T 09-03-2017 UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 255 330 7.2E-11 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 247 6.4E-35 T 09-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 Gene3D G3DSA:3.30.1360.120 137 223 3.5E-17 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 Gene3D G3DSA:3.30.1360.120 12 50 3.5E-17 T 09-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 PIRSF PIRSF006487 1 347 1.0E-40 T 09-03-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 SUPERFAMILY SSF101790 280 330 1.8E-6 T 09-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain UA74_RS05810 298b6a4fe28c7d26f434c2cf11571be3 354 Gene3D G3DSA:2.40.30.110 276 329 1.7E-7 T 09-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 SUPERFAMILY SSF51735 125 283 4.67E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27785 e031c84732409f177cc1a818773ece03 288 Gene3D G3DSA:3.40.192.10 10 141 7.7E-40 T 09-03-2017 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 SUPERFAMILY SSF53223 5 124 1.25E-32 T 09-03-2017 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 284 2.9E-61 T 09-03-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 Hamap MF_01576 Bifunctional protein FolD [folD]. 6 285 36.038 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 8 123 4.4E-31 T 09-03-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 Gene3D G3DSA:3.40.50.720 142 266 8.2E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27785 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 157 177 2.2E-63 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 208 237 2.2E-63 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 112 133 2.2E-63 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 2.2E-63 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 77 104 2.2E-63 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS27785 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 36 58 2.2E-63 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 275 2.3E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 151 3.6E-8 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 299 3.6E-8 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 3.6E-8 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 91 99 3.6E-8 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 Gene3D G3DSA:3.50.50.60 1 93 2.5E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.5E-11 T 09-03-2017 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 90 108 1.5E-11 T 09-03-2017 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.5E-11 T 09-03-2017 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 SUPERFAMILY SSF51905 1 290 5.96E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07050 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 Gene3D G3DSA:3.50.50.60 94 282 6.6E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS19100 8653039bbb9e2958188bc0425c84f70d 311 Gene3D G3DSA:1.10.287.100 232 270 4.2E-15 T 09-03-2017 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 UA74_RS19100 8653039bbb9e2958188bc0425c84f70d 311 SUPERFAMILY SSF159659 5 271 1.44E-82 T 09-03-2017 UA74_RS19100 8653039bbb9e2958188bc0425c84f70d 311 Pfam PF09754 PAC2 family 27 248 1.9E-44 T 09-03-2017 IPR019151 Proteasome assembly chaperone 2 UA74_RS19100 8653039bbb9e2958188bc0425c84f70d 311 PIRSF PIRSF028754 7 311 4.5E-91 T 09-03-2017 IPR008492 Protein of unknown function DUF774 UA74_RS04425 ce6ba490596ef0968a5e42c6ad5e1e22 354 Pfam PF00005 ABC transporter 54 205 1.0E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04425 ce6ba490596ef0968a5e42c6ad5e1e22 354 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS04425 ce6ba490596ef0968a5e42c6ad5e1e22 354 Gene3D G3DSA:3.40.50.300 24 279 3.6E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04425 ce6ba490596ef0968a5e42c6ad5e1e22 354 SMART SM00382 62 255 1.9E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04425 ce6ba490596ef0968a5e42c6ad5e1e22 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 257 324 7.0E-16 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS04425 ce6ba490596ef0968a5e42c6ad5e1e22 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 345 1.4E-25 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS04425 ce6ba490596ef0968a5e42c6ad5e1e22 354 SUPERFAMILY SSF52540 25 277 7.43E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13965 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 Gene3D G3DSA:3.40.50.720 53 161 4.3E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13965 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 SUPERFAMILY SSF55347 149 340 2.62E-29 T 09-03-2017 UA74_RS13965 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 53 141 3.2E-8 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS13965 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 SUPERFAMILY SSF51735 52 176 1.49E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13965 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 Gene3D G3DSA:3.30.360.10 162 377 5.6E-35 T 09-03-2017 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 09-03-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 09-03-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.6E-53 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.223 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 SUPERFAMILY SSF54686 2 136 1.44E-53 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.3E-45 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 Gene3D G3DSA:3.90.1170.10 23 136 1.2E-50 T 09-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.3E-36 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.3E-36 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.3E-36 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02965 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.3E-36 T 09-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS27265 b6cd802f4eba40b52021d1c98b8fcb51 292 Gene3D G3DSA:3.20.20.150 19 291 1.5E-51 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27265 b6cd802f4eba40b52021d1c98b8fcb51 292 SUPERFAMILY SSF51658 22 290 1.44E-46 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27265 b6cd802f4eba40b52021d1c98b8fcb51 292 Pfam PF01261 Xylose isomerase-like TIM barrel 39 248 1.2E-29 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 SUPERFAMILY SSF53187 179 358 2.51E-43 T 09-03-2017 UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 SUPERFAMILY SSF47090 88 151 1.02E-18 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 182 355 2.2E-38 T 09-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 Gene3D G3DSA:1.10.101.10 2 76 1.8E-16 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 Gene3D G3DSA:1.10.101.10 90 153 1.4E-19 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 SMART SM00646 240 355 3.0E-31 T 09-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 Gene3D G3DSA:3.40.630.40 179 358 1.7E-44 T 09-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 SUPERFAMILY SSF47090 3 73 4.97E-12 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 Pfam PF01471 Putative peptidoglycan binding domain 10 72 1.1E-9 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS30410 b77da52b00c81a388475ae1ee9df2635 384 Pfam PF01471 Putative peptidoglycan binding domain 94 149 2.6E-17 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS04260 cebe49da4d0fa9521555c9ad8695ed95 104 SUPERFAMILY SSF140453 5 102 1.02E-8 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS04260 cebe49da4d0fa9521555c9ad8695ed95 104 Pfam PF06013 Proteins of 100 residues with WXG 5 94 7.5E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS04260 cebe49da4d0fa9521555c9ad8695ed95 104 Gene3D G3DSA:1.10.287.1060 1 101 8.5E-7 T 09-03-2017 UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 Pfam PF00664 ABC transporter transmembrane region 45 302 3.0E-23 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 Gene3D G3DSA:3.40.50.300 407 575 3.2E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 SUPERFAMILY SSF52540 376 564 2.25E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 SUPERFAMILY SSF90123 20 335 6.02E-49 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 Gene3D G3DSA:1.20.1560.10 28 339 6.3E-43 T 09-03-2017 UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 ProSitePatterns PS00211 ABC transporters family signature. 259 273 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS14975 5e6cc778584e67b48c7ef9ad61f67449 605 Pfam PF00005 ABC transporter 391 496 6.4E-8 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00640 38aa5bd9077b3473bdad21dd0ac0ec17 228 Pfam PF00535 Glycosyl transferase family 2 9 130 1.6E-20 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS00640 38aa5bd9077b3473bdad21dd0ac0ec17 228 Gene3D G3DSA:3.90.550.10 9 129 5.8E-14 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00640 38aa5bd9077b3473bdad21dd0ac0ec17 228 SUPERFAMILY SSF53448 6 210 1.34E-28 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS02610 170af7fe197d033806202bdacd331dea 340 SUPERFAMILY SSF48576 28 339 7.36E-85 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS02610 170af7fe197d033806202bdacd331dea 340 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 220 232 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS02610 170af7fe197d033806202bdacd331dea 340 Pfam PF00348 Polyprenyl synthetase 50 291 1.3E-59 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS02610 170af7fe197d033806202bdacd331dea 340 Gene3D G3DSA:1.10.600.10 27 339 9.9E-92 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS20430 03fca6d9b0a9c46fc3ad2a6efeee7f8c 444 SUPERFAMILY SSF103473 2 385 5.49E-43 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS20430 03fca6d9b0a9c46fc3ad2a6efeee7f8c 444 Gene3D G3DSA:1.20.1250.20 2 180 4.3E-20 T 09-03-2017 UA74_RS20430 03fca6d9b0a9c46fc3ad2a6efeee7f8c 444 Gene3D G3DSA:1.20.1250.20 209 377 5.1E-17 T 09-03-2017 UA74_RS20430 03fca6d9b0a9c46fc3ad2a6efeee7f8c 444 Pfam PF05977 Transmembrane secretion effector 3 377 5.5E-39 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS03450 d19c1e274fa8d6f13c7e19de162a7a44 373 Gene3D G3DSA:3.40.50.150 14 238 3.0E-45 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS03450 d19c1e274fa8d6f13c7e19de162a7a44 373 SUPERFAMILY SSF53335 4 199 1.08E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS03450 d19c1e274fa8d6f13c7e19de162a7a44 373 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 11 215 2.3E-26 T 09-03-2017 UA74_RS10785 f6dda3108ef39093bc881ff46f7a00dc 329 Pfam PF03741 Integral membrane protein TerC family 70 273 1.1E-50 T 09-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 UA74_RS10785 f6dda3108ef39093bc881ff46f7a00dc 329 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 319 4.8E-116 T 09-03-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 UA74_RS17100 f8624abd27e5c0e0cd0ac5194d793ad8 476 Gene3D G3DSA:2.115.10.20 170 416 4.1E-11 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS17100 f8624abd27e5c0e0cd0ac5194d793ad8 476 Pfam PF03664 Glycosyl hydrolase family 62 159 443 2.5E-59 T 09-03-2017 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UA74_RS17100 f8624abd27e5c0e0cd0ac5194d793ad8 476 Pfam PF00553 Cellulose binding domain 47 147 4.3E-28 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS17100 f8624abd27e5c0e0cd0ac5194d793ad8 476 SMART SM00637 47 147 5.5E-40 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS17100 f8624abd27e5c0e0cd0ac5194d793ad8 476 SUPERFAMILY SSF75005 186 467 9.42E-22 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS17100 f8624abd27e5c0e0cd0ac5194d793ad8 476 SUPERFAMILY SSF49384 44 149 1.05E-27 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS17100 f8624abd27e5c0e0cd0ac5194d793ad8 476 Gene3D G3DSA:2.60.40.290 46 149 1.8E-33 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS00770 e73186704380d4464e3bd39e0fb65555 412 SUPERFAMILY SSF53474 144 343 1.46E-16 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS00770 e73186704380d4464e3bd39e0fb65555 412 Pfam PF12740 Chlorophyllase enzyme 144 286 5.5E-7 T 09-03-2017 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 UA74_RS00770 e73186704380d4464e3bd39e0fb65555 412 Gene3D G3DSA:3.40.50.1820 146 409 1.8E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS00770 e73186704380d4464e3bd39e0fb65555 412 Gene3D G3DSA:3.40.50.1820 50 98 1.8E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12335 88a6ef20bf881062dd6f2bf2a1190ecc 176 Gene3D G3DSA:1.10.10.10 28 100 1.0E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12335 88a6ef20bf881062dd6f2bf2a1190ecc 176 SUPERFAMILY SSF46785 51 127 2.04E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11810 8452bead4c671e29101f357951d72d98 212 SUPERFAMILY SSF55961 3 142 5.5E-26 T 09-03-2017 UA74_RS11810 8452bead4c671e29101f357951d72d98 212 Gene3D G3DSA:3.30.530.20 4 132 4.8E-10 T 09-03-2017 IPR023393 START-like domain UA74_RS11810 8452bead4c671e29101f357951d72d98 212 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 123 2.7E-17 T 09-03-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain UA74_RS20155 4ff36f72701cf46fd6dd94f9d571424a 477 SUPERFAMILY SSF46785 338 424 5.56E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20155 4ff36f72701cf46fd6dd94f9d571424a 477 Gene3D G3DSA:1.10.10.10 340 407 7.5E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04635 1ce24651003d971a9032ffaa39cb65da 130 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 5 82 2.9E-18 T 09-03-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 UA74_RS04635 1ce24651003d971a9032ffaa39cb65da 130 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 124 14.144 T 09-03-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 UA74_RS04635 1ce24651003d971a9032ffaa39cb65da 130 Pfam PF02416 mttA/Hcf106 family 5 41 1.6E-9 T 09-03-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 UA74_RS04635 1ce24651003d971a9032ffaa39cb65da 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 5.3E-10 T 09-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 UA74_RS04635 1ce24651003d971a9032ffaa39cb65da 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 5.3E-10 T 09-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 UA74_RS04635 1ce24651003d971a9032ffaa39cb65da 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 5.3E-10 T 09-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 UA74_RS29950 60044294f8d232dfeefa97c3554af27a 193 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.449 T 09-03-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 UA74_RS29950 60044294f8d232dfeefa97c3554af27a 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 4.9E-63 T 09-03-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 UA74_RS29950 60044294f8d232dfeefa97c3554af27a 193 Pfam PF00692 dUTPase 70 176 7.3E-10 T 09-03-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 UA74_RS29950 60044294f8d232dfeefa97c3554af27a 193 Gene3D G3DSA:2.70.40.10 2 183 8.2E-65 T 09-03-2017 IPR029054 dUTPase-like UA74_RS29950 60044294f8d232dfeefa97c3554af27a 193 SUPERFAMILY SSF51283 2 183 1.7E-56 T 09-03-2017 IPR029054 dUTPase-like UA74_RS18930 bd16f509a84994021b42cd37699f868f 370 SUPERFAMILY SSF55347 136 276 1.64E-26 T 09-03-2017 UA74_RS18930 bd16f509a84994021b42cd37699f868f 370 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 118 3.0E-19 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS18930 bd16f509a84994021b42cd37699f868f 370 SUPERFAMILY SSF51735 4 161 3.49E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18930 bd16f509a84994021b42cd37699f868f 370 Gene3D G3DSA:3.40.50.720 4 148 5.5E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18930 bd16f509a84994021b42cd37699f868f 370 Gene3D G3DSA:3.30.360.10 149 345 1.0E-39 T 09-03-2017 UA74_RS18930 bd16f509a84994021b42cd37699f868f 370 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 245 2.9E-12 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 9 628 3.7E-158 T 09-03-2017 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 4 629 2.9E-197 T 09-03-2017 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 SUPERFAMILY SSF48239 304 628 1.1E-96 T 09-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 308 628 4.4E-121 T 09-03-2017 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 11 293 3.3E-94 T 09-03-2017 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 Gene3D G3DSA:1.50.10.20 287 628 6.8E-106 T 09-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 Gene3D G3DSA:1.50.10.20 34 282 3.1E-50 T 09-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_RS12840 4464dbbe49554e4e87a8f46a8b7c09a8 648 SUPERFAMILY SSF48239 35 290 3.82E-52 T 09-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_RS12860 1078251a0cb25d147281a9eb0b6e0dd1 433 Gene3D G3DSA:3.30.565.10 329 413 2.5E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS12860 1078251a0cb25d147281a9eb0b6e0dd1 433 SUPERFAMILY SSF55874 293 416 4.98E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS12860 1078251a0cb25d147281a9eb0b6e0dd1 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 413 1.8E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS16165 683c8ffa56952faca48d46c4c38448d0 144 Pfam PF01638 HxlR-like helix-turn-helix 16 114 1.4E-11 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS16165 683c8ffa56952faca48d46c4c38448d0 144 SUPERFAMILY SSF46785 10 120 7.24E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16165 683c8ffa56952faca48d46c4c38448d0 144 Gene3D G3DSA:1.10.10.10 9 118 1.9E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11645 0c731d427166bb20533430d412fbff11 143 SUPERFAMILY SSF141322 78 139 3.79E-7 T 09-03-2017 UA74_RS11645 0c731d427166bb20533430d412fbff11 143 Pfam PF01957 NfeD-like C-terminal, partner-binding 5 140 5.4E-22 T 09-03-2017 IPR002810 NfeD-like, C-terminal domain UA74_RS11645 0c731d427166bb20533430d412fbff11 143 Gene3D G3DSA:2.40.50.140 81 140 4.9E-23 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS17315 14590349e2dd22d70b7b00cd978e1a76 236 SUPERFAMILY SSF53335 6 222 2.37E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17315 14590349e2dd22d70b7b00cd978e1a76 236 Gene3D G3DSA:2.20.130.10 152 199 8.7E-26 T 09-03-2017 UA74_RS17315 14590349e2dd22d70b7b00cd978e1a76 236 Pfam PF13649 Methyltransferase domain 43 133 1.8E-14 T 09-03-2017 UA74_RS17315 14590349e2dd22d70b7b00cd978e1a76 236 Gene3D G3DSA:3.40.50.150 200 220 6.9E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17315 14590349e2dd22d70b7b00cd978e1a76 236 Gene3D G3DSA:3.40.50.150 2 151 6.9E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 12 405 2.5E-145 T 09-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 SUPERFAMILY SSF53720 3 415 1.82E-116 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 322 343 - T 09-03-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 Pfam PF00171 Aldehyde dehydrogenase family 3 290 5.7E-15 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 Gene3D G3DSA:3.40.605.10 3 223 1.8E-95 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 Gene3D G3DSA:3.40.605.10 374 415 1.8E-95 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 4 415 42.005 T 09-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 Gene3D G3DSA:3.40.309.10 226 373 3.1E-48 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS08335 0e677074a2cb0fcf0965e847b238f530 418 PIRSF PIRSF000151 1 416 4.2E-171 T 09-03-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 Gene3D G3DSA:3.90.870.10 12 222 6.4E-96 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 210 6.7E-74 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 16 209 2.6E-86 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 SUPERFAMILY SSF142695 216 387 5.1E-71 T 09-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 218 408 2.0E-72 T 09-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 215 411 40.561 T 09-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 Pfam PF00925 GTP cyclohydrolase II 218 383 4.5E-72 T 09-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 11 407 55.494 T 09-03-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 PIRSF PIRSF001259 10 414 9.4E-179 T 09-03-2017 UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 SUPERFAMILY SSF55821 14 217 5.95E-82 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain UA74_RS12400 229b20cba7146c261b559068ca6006b5 443 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 10 214 38.239 T 09-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 172 788 2.7E-207 T 09-03-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 SUPERFAMILY SSF48168 27 243 4.19E-58 T 09-03-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 Pfam PF03477 ATP cone domain 22 106 1.4E-4 T 09-03-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 PRINTS PR01183 Ribonucleotide reductase large chain signature 640 667 8.7E-45 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 PRINTS PR01183 Ribonucleotide reductase large chain signature 563 586 8.7E-45 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 PRINTS PR01183 Ribonucleotide reductase large chain signature 320 339 8.7E-45 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 PRINTS PR01183 Ribonucleotide reductase large chain signature 535 557 8.7E-45 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 PRINTS PR01183 Ribonucleotide reductase large chain signature 455 466 8.7E-45 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 PRINTS PR01183 Ribonucleotide reductase large chain signature 497 520 8.7E-45 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 Pfam PF02867 Ribonucleotide reductase, barrel domain 245 785 2.2E-179 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 629 651 - T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 SUPERFAMILY SSF51998 244 689 1.89E-175 T 09-03-2017 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 SUPERFAMILY SSF51998 720 790 1.89E-175 T 09-03-2017 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 Gene3D G3DSA:3.20.70.20 640 685 3.5E-82 T 09-03-2017 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 Gene3D G3DSA:3.20.70.20 746 790 3.5E-82 T 09-03-2017 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 Gene3D G3DSA:3.20.70.20 421 583 3.5E-82 T 09-03-2017 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 Gene3D G3DSA:3.20.70.20 164 366 3.5E-82 T 09-03-2017 UA74_RS11350 70b3c4df9915fd1677563ccb274ad447 844 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 168 241 3.1E-21 T 09-03-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS17275 fa9f325f2c220f39a1553398bda3d62b 225 Pfam PF16715 Cyclodipeptide synthase 9 208 5.0E-44 T 09-03-2017 IPR030903 Cyclodileucine synthase GO:0016755 UA74_RS17275 fa9f325f2c220f39a1553398bda3d62b 225 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 17 208 3.2E-48 T 09-03-2017 IPR030903 Cyclodileucine synthase GO:0016755 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 Gene3D G3DSA:2.40.10.10 77 135 1.2E-15 T 09-03-2017 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 SMART SM00020 43 262 4.7E-69 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 216 228 4.6E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 71 86 4.6E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 127 141 4.6E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 Gene3D G3DSA:2.40.10.10 136 266 1.5E-40 T 09-03-2017 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 SUPERFAMILY SSF50494 42 266 1.28E-66 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 Pfam PF00089 Trypsin 44 259 1.0E-53 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 217 228 - T 09-03-2017 IPR033116 Serine proteases, trypsin family, serine active site UA74_RS11320 9f0d2bec823bb8fc9f19183fcd513d68 268 Gene3D G3DSA:2.40.10.10 44 76 6.2E-13 T 09-03-2017 UA74_RS04750 0244f4acf2b191c621d958dfacaaddfe 228 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 21 200 1.7E-81 T 09-03-2017 UA74_RS04750 0244f4acf2b191c621d958dfacaaddfe 228 Gene3D G3DSA:1.20.1260.10 19 146 2.2E-5 T 09-03-2017 IPR012347 Ferritin-related UA74_RS04750 0244f4acf2b191c621d958dfacaaddfe 228 SUPERFAMILY SSF47240 23 169 1.53E-7 T 09-03-2017 IPR009078 Ferritin-like superfamily UA74_RS16680 94d31def9bced8f247da32cd70baf296 155 SUPERFAMILY SSF46785 12 93 1.03E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16680 94d31def9bced8f247da32cd70baf296 155 Gene3D G3DSA:1.10.10.10 11 81 2.8E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16680 94d31def9bced8f247da32cd70baf296 155 Pfam PF12802 MarR family 19 78 2.7E-12 T 09-03-2017 UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 Gene3D G3DSA:3.40.50.150 1039 1218 4.9E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 Gene3D G3DSA:3.90.550.10 8 252 1.7E-4 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 SUPERFAMILY SSF53756 517 783 1.15E-31 T 09-03-2017 UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1048 1190 6.7E-22 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 Pfam PF00534 Glycosyl transferases group 1 591 761 7.2E-13 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 SUPERFAMILY SSF53335 1016 1218 8.59E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 SUPERFAMILY SSF53448 6 256 1.29E-13 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 Pfam PF05050 Methyltransferase FkbM domain 1051 1215 7.1E-13 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS00305 06c2929f0b2c2319daf7530c13fef3e7 1251 Gene3D G3DSA:3.40.50.2000 596 761 2.9E-8 T 09-03-2017 UA74_RS27120 0a8ba23d39c574486c8e012397bf09ca 372 SUPERFAMILY SSF54506 170 362 3.45E-43 T 09-03-2017 UA74_RS27120 0a8ba23d39c574486c8e012397bf09ca 372 Gene3D G3DSA:3.10.310.10 3 174 1.4E-61 T 09-03-2017 UA74_RS27120 0a8ba23d39c574486c8e012397bf09ca 372 SUPERFAMILY SSF54506 2 166 2.51E-50 T 09-03-2017 UA74_RS27120 0a8ba23d39c574486c8e012397bf09ca 372 Gene3D G3DSA:3.10.310.10 175 344 1.7E-45 T 09-03-2017 UA74_RS27120 0a8ba23d39c574486c8e012397bf09ca 372 Pfam PF04303 PrpF protein 2 358 5.7E-97 T 09-03-2017 IPR007400 PrpF protein UA74_RS01305 1078c1db7d3307518219b193f55771d1 312 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 10 304 35.433 T 09-03-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 UA74_RS01305 1078c1db7d3307518219b193f55771d1 312 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 16 304 1.2E-95 T 09-03-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 UA74_RS01305 1078c1db7d3307518219b193f55771d1 312 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 194 211 - T 09-03-2017 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 UA74_RS01305 1078c1db7d3307518219b193f55771d1 312 Pfam PF13580 SIS domain 50 167 2.1E-6 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS01305 1078c1db7d3307518219b193f55771d1 312 Gene3D G3DSA:3.40.50.10490 12 258 9.9E-74 T 09-03-2017 UA74_RS01305 1078c1db7d3307518219b193f55771d1 312 SUPERFAMILY SSF53697 16 257 3.56E-59 T 09-03-2017 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 3 412 2.9E-207 T 09-03-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 SUPERFAMILY SSF52374 31 334 2.65E-68 T 09-03-2017 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 53.813 T 09-03-2017 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 Gene3D G3DSA:3.40.50.620 37 328 9.8E-73 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 3.8E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 3.8E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 3.8E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 3.8E-24 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS14205 39c01b3706342bbe4fa4a375ac986d2b 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 37 332 4.4E-81 T 09-03-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 UA74_RS07320 619edbb3ceae57ad07263c8abe0f25b9 321 SUPERFAMILY SSF52540 3 314 5.7E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07320 619edbb3ceae57ad07263c8abe0f25b9 321 SMART SM00382 49 307 0.0034 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07320 619edbb3ceae57ad07263c8abe0f25b9 321 Pfam PF03308 ArgK protein 22 283 4.3E-97 T 09-03-2017 UA74_RS07320 619edbb3ceae57ad07263c8abe0f25b9 321 Gene3D G3DSA:3.40.50.300 50 254 4.9E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07320 619edbb3ceae57ad07263c8abe0f25b9 321 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 315 3.5E-101 T 09-03-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 28 49 1.1E-30 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 6 21 1.1E-30 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 63 75 1.1E-30 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 84 97 1.1E-30 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 6 30 - T 09-03-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 97 2.7E-35 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 SUPERFAMILY SSF50129 4 98 1.04E-34 T 09-03-2017 IPR011032 GroES-like UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 Hamap MF_00580 10 kDa chaperonin [groS]. 5 98 26.046 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 Gene3D G3DSA:2.30.33.40 5 97 2.1E-38 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS28100 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 SMART SM00883 5 97 4.2E-55 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 40 9.2E-6 T 09-03-2017 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 Pfam PF00732 GMC oxidoreductase 184 272 7.8E-8 T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 Gene3D G3DSA:3.50.50.60 191 295 7.1E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 Gene3D G3DSA:3.50.50.60 353 366 7.1E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 Gene3D G3DSA:3.50.50.60 5 122 7.1E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 Gene3D G3DSA:3.50.50.60 436 503 7.1E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 Pfam PF05199 GMC oxidoreductase 436 496 2.1E-16 T 09-03-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 SUPERFAMILY SSF51905 6 293 4.49E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11010 daccf22ac9c98b3bf9af253efb45a749 715 SUPERFAMILY SSF51905 442 504 4.49E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07500 a5d714cc30fa92653d4871e815a12683 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 4.8E-10 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS07500 a5d714cc30fa92653d4871e815a12683 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 4.8E-10 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS07500 a5d714cc30fa92653d4871e815a12683 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 4.8E-10 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS07500 a5d714cc30fa92653d4871e815a12683 112 Gene3D G3DSA:1.10.10.10 2 99 2.1E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07500 a5d714cc30fa92653d4871e815a12683 112 SMART SM00418 2 83 1.5E-19 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS07500 a5d714cc30fa92653d4871e815a12683 112 Pfam PF12840 Helix-turn-helix domain 2 60 7.3E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07500 a5d714cc30fa92653d4871e815a12683 112 SUPERFAMILY SSF46785 3 102 1.93E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09425 43ad774fd39c1e2aedb7400a6025128c 311 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 18 227 5.7E-66 T 09-03-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS09425 43ad774fd39c1e2aedb7400a6025128c 311 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 38 190 5.6E-50 T 09-03-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 UA74_RS09425 43ad774fd39c1e2aedb7400a6025128c 311 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 16 301 16.933 T 09-03-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS09425 43ad774fd39c1e2aedb7400a6025128c 311 SUPERFAMILY SSF55120 17 235 3.52E-69 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS09425 43ad774fd39c1e2aedb7400a6025128c 311 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 191 231 7.6E-11 T 09-03-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 UA74_RS09425 43ad774fd39c1e2aedb7400a6025128c 311 SUPERFAMILY SSF88697 247 303 2.58E-12 T 09-03-2017 IPR015947 PUA-like domain UA74_RS09425 43ad774fd39c1e2aedb7400a6025128c 311 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 247 302 3.6E-20 T 09-03-2017 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS03815 831dcb7a54794668e5fc7066dcfc9e3e 352 Gene3D G3DSA:3.30.470.20 226 315 3.6E-5 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS03815 831dcb7a54794668e5fc7066dcfc9e3e 352 SUPERFAMILY SSF56059 223 328 1.17E-9 T 09-03-2017 UA74_RS05130 8cfc848aa043b978bfa9b180d60ec338 317 Gene3D G3DSA:3.40.50.300 91 156 1.4E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05130 8cfc848aa043b978bfa9b180d60ec338 317 SUPERFAMILY SSF53795 91 152 2.81E-8 T 09-03-2017 UA74_RS04625 c1d4b563bc76b0ee6a92bc6027b3f745 289 Pfam PF13490 Putative zinc-finger 15 45 2.6E-5 T 09-03-2017 IPR027383 Putative zinc-finger UA74_RS02370 2ef5d6cf3d2018627054d220b4c5fdff 521 Gene3D G3DSA:1.10.510.10 98 264 4.8E-42 T 09-03-2017 UA74_RS02370 2ef5d6cf3d2018627054d220b4c5fdff 521 Pfam PF00069 Protein kinase domain 15 261 2.3E-40 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS02370 2ef5d6cf3d2018627054d220b4c5fdff 521 SMART SM00220 15 272 1.7E-46 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS02370 2ef5d6cf3d2018627054d220b4c5fdff 521 Gene3D G3DSA:3.30.200.20 8 92 7.4E-16 T 09-03-2017 UA74_RS02370 2ef5d6cf3d2018627054d220b4c5fdff 521 SUPERFAMILY SSF56112 11 261 1.33E-65 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS02370 2ef5d6cf3d2018627054d220b4c5fdff 521 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS02370 2ef5d6cf3d2018627054d220b4c5fdff 521 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS16860 5804da217d3deac841ca2b72d8ac870a 201 Pfam PF13305 WHG domain 94 175 5.0E-10 T 09-03-2017 IPR025996 WHG domain UA74_RS16860 5804da217d3deac841ca2b72d8ac870a 201 SUPERFAMILY SSF46689 8 81 4.0E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS16860 5804da217d3deac841ca2b72d8ac870a 201 Gene3D G3DSA:1.10.357.10 8 196 5.3E-33 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS16860 5804da217d3deac841ca2b72d8ac870a 201 SUPERFAMILY SSF48498 91 178 6.67E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS16860 5804da217d3deac841ca2b72d8ac870a 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.1E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15600 28ec2bb91a101919470c25e9a76dac7d 189 Pfam PF01872 RibD C-terminal domain 4 180 7.4E-25 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS15600 28ec2bb91a101919470c25e9a76dac7d 189 Gene3D G3DSA:3.40.430.10 4 188 5.4E-34 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS15600 28ec2bb91a101919470c25e9a76dac7d 189 SUPERFAMILY SSF53597 1 185 1.22E-34 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS25440 9c9704786bc1e529b49f65c16241c270 330 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 9 267 3.8E-52 T 09-03-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UA74_RS25440 9c9704786bc1e529b49f65c16241c270 330 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 312 92.453 T 09-03-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UA74_RS25440 9c9704786bc1e529b49f65c16241c270 330 Pfam PF03186 CobD/Cbib protein 9 290 9.0E-90 T 09-03-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 Gene3D G3DSA:3.40.50.300 217 376 1.2E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 SUPERFAMILY SSF52540 82 366 9.29E-73 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 Pfam PF00270 DEAD/DEAH box helicase 37 197 4.1E-49 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 SMART SM00487 31 227 1.3E-53 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 SMART SM00490 267 348 1.3E-33 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 Pfam PF00271 Helicase conserved C-terminal domain 240 348 1.2E-28 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 160 168 - T 09-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site UA74_RS04745 b9f77f4b8a6c25500f4a446158e29618 538 Gene3D G3DSA:3.40.50.300 6 216 1.0E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22455 cca8a5a18f8217cf108c6a5edf1ac782 282 Pfam PF13460 NAD(P)H-binding 13 106 1.5E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22455 cca8a5a18f8217cf108c6a5edf1ac782 282 Gene3D G3DSA:3.40.50.720 6 214 1.8E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22455 cca8a5a18f8217cf108c6a5edf1ac782 282 SUPERFAMILY SSF51735 7 272 4.92E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08360 4a916c04e77de7961b4ec911699705ca 204 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 09-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UA74_RS08360 4a916c04e77de7961b4ec911699705ca 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 198 8.1E-51 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS08360 4a916c04e77de7961b4ec911699705ca 204 PIRSF PIRSF000709 4 173 1.1E-12 T 09-03-2017 UA74_RS08360 4a916c04e77de7961b4ec911699705ca 204 SMART SM00855 5 157 6.7E-22 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS08360 4a916c04e77de7961b4ec911699705ca 204 Gene3D G3DSA:3.40.50.1240 5 199 1.5E-55 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS08360 4a916c04e77de7961b4ec911699705ca 204 SUPERFAMILY SSF53254 5 199 4.82E-53 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 SUPERFAMILY SSF52402 4 185 5.5E-31 T 09-03-2017 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 Gene3D G3DSA:3.90.1260.10 176 372 4.4E-62 T 09-03-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 Pfam PF00764 Arginosuccinate synthase 16 404 3.2E-56 T 09-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 Gene3D G3DSA:3.40.50.620 4 175 6.6E-40 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 09-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 SUPERFAMILY SSF69864 190 435 9.03E-75 T 09-03-2017 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 Gene3D G3DSA:1.10.287.400 377 435 4.7E-28 T 09-03-2017 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 09-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 473 78.926 T 09-03-2017 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS17150 f87848bd11283bcf24e0be014c66e413 482 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 4.5E-137 T 09-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 Pfam PF13183 4Fe-4S dicluster domain 177 249 3.6E-12 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 36 259 5.2E-78 T 09-03-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 179 190 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 33 143 1.1E-33 T 09-03-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 Gene3D G3DSA:3.10.20.30 28 137 7.0E-36 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 SUPERFAMILY SSF54292 30 137 5.11E-25 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 Gene3D G3DSA:1.10.1060.10 138 263 7.4E-40 T 09-03-2017 UA74_RS27695 dedb10bd064317f07c4374a3bab7a658 267 SUPERFAMILY SSF46548 138 264 9.24E-33 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_RS22365 73d38591ec57b38d6cc51fc3d6379f37 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 274 4.8E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22365 73d38591ec57b38d6cc51fc3d6379f37 287 SUPERFAMILY SSF161098 46 273 1.57E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22365 73d38591ec57b38d6cc51fc3d6379f37 287 Gene3D G3DSA:1.10.3720.10 52 280 2.6E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 SUPERFAMILY SSF56112 280 556 1.86E-47 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 Gene3D G3DSA:3.30.200.20 285 376 4.7E-17 T 09-03-2017 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 SMART SM00220 290 545 3.7E-26 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 Gene3D G3DSA:1.10.510.10 377 498 2.2E-24 T 09-03-2017 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 Pfam PF16918 Protein kinase G tetratricopeptide repeat 561 885 1.6E-88 T 09-03-2017 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 Gene3D G3DSA:1.25.40.10 624 759 8.5E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 Pfam PF16919 Protein kinase G rubredoxin domain 168 289 7.8E-36 T 09-03-2017 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 SUPERFAMILY SSF48452 650 757 1.1E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11740 69b22aedca68c74ce3ca8e3b3105ea7b 887 Pfam PF00069 Protein kinase domain 290 535 7.9E-30 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS13105 9bc836a66513663e493bef8644787d84 214 Pfam PF08044 Domain of unknown function (DUF1707) 13 65 3.9E-21 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 SUPERFAMILY SSF53187 233 469 6.86E-56 T 09-03-2017 UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 SUPERFAMILY SSF53187 47 98 6.86E-56 T 09-03-2017 UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 Gene3D G3DSA:3.40.630.10 248 472 7.6E-59 T 09-03-2017 UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 Gene3D G3DSA:3.40.630.10 49 109 7.6E-59 T 09-03-2017 UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 Gene3D G3DSA:3.50.30.30 116 235 4.9E-28 T 09-03-2017 UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 SUPERFAMILY SSF52025 116 233 8.11E-16 T 09-03-2017 UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 Pfam PF02225 PA domain 138 226 7.6E-13 T 09-03-2017 IPR003137 PA domain UA74_RS00720 2115658e05adacf0fb43310d609414ec 506 Pfam PF04389 Peptidase family M28 249 463 1.5E-36 T 09-03-2017 IPR007484 Peptidase M28 UA74_RS10790 4493172216bf6b88dcb32d6ecce6de48 421 SUPERFAMILY SSF51338 370 415 1.92E-17 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS10790 4493172216bf6b88dcb32d6ecce6de48 421 SUPERFAMILY SSF51338 2 62 1.92E-17 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS10790 4493172216bf6b88dcb32d6ecce6de48 421 SUPERFAMILY SSF51556 62 368 3.89E-95 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS10790 4493172216bf6b88dcb32d6ecce6de48 421 Pfam PF01979 Amidohydrolase family 58 412 1.7E-51 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS10790 4493172216bf6b88dcb32d6ecce6de48 421 Gene3D G3DSA:3.20.20.140 72 354 4.9E-91 T 09-03-2017 UA74_RS10790 4493172216bf6b88dcb32d6ecce6de48 421 Gene3D G3DSA:2.30.40.10 355 417 1.6E-12 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS10790 4493172216bf6b88dcb32d6ecce6de48 421 Gene3D G3DSA:2.30.40.10 4 71 2.0E-13 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.9E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.9E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.9E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.9E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.9E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.9E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 2.6E-53 T 09-03-2017 UA74_RS19465 04f435da28174017dbf8360928122fe1 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS19465 04f435da28174017dbf8360928122fe1 244 SUPERFAMILY SSF51735 5 243 1.18E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.3E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.3E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.3E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19465 04f435da28174017dbf8360928122fe1 244 Gene3D G3DSA:3.40.50.720 5 243 1.1E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19465 04f435da28174017dbf8360928122fe1 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 186 0.0012 T 09-03-2017 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 SUPERFAMILY SSF47729 1 91 9.42E-25 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 SMART SM00411 1 89 3.8E-33 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 Pfam PF00216 Bacterial DNA-binding protein 1 88 1.9E-25 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 Gene3D G3DSA:4.10.520.10 1 89 4.0E-28 T 09-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 2.3E-13 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 2.3E-13 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 2.3E-13 T 09-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 UA74_RS26030 2c87d99456b8e80956f90a907d2f3231 292 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 09-03-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 UA74_RS25250 3a6b49df0174ce112d47d12599210636 156 Pfam PF06271 RDD family 78 149 8.5E-6 T 09-03-2017 IPR010432 RDD UA74_RS25250 3a6b49df0174ce112d47d12599210636 156 PIRSF PIRSF021697 1 155 5.0E-44 T 09-03-2017 IPR016795 Uncharacterised conserved protein UCP021697, membrane UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 SMART SM00866 103 243 2.6E-46 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 82 1.1E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.0E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.0E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 SUPERFAMILY SSF46785 18 93 8.88E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 Gene3D G3DSA:1.10.10.10 18 80 2.9E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 Gene3D G3DSA:3.40.1410.10 81 249 8.9E-58 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 SMART SM00345 26 83 1.7E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 SUPERFAMILY SSF64288 71 249 3.61E-55 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS01950 b2beb42205335e4659d25bf357b8ef2d 258 Pfam PF07702 UTRA domain 103 243 1.4E-45 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS03470 b4aa706bba84931e3eafbf80587c720a 62 Pfam PF04149 Domain of unknown function (DUF397) 12 60 1.3E-9 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS11590 6ecfa426b156343d6a06d3a97d7ec2be 248 SUPERFAMILY SSF53448 14 94 2.09E-20 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS11590 6ecfa426b156343d6a06d3a97d7ec2be 248 SUPERFAMILY SSF53448 134 232 2.09E-20 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS11590 6ecfa426b156343d6a06d3a97d7ec2be 248 Pfam PF12804 MobA-like NTP transferase domain 18 210 1.4E-23 T 09-03-2017 IPR025877 MobA-like NTP transferase UA74_RS11590 6ecfa426b156343d6a06d3a97d7ec2be 248 Gene3D G3DSA:3.90.550.10 135 237 8.4E-29 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS11590 6ecfa426b156343d6a06d3a97d7ec2be 248 Gene3D G3DSA:3.90.550.10 14 94 8.4E-29 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS21915 9d93f802f45422402049d83f84d9834f 421 SUPERFAMILY SSF53850 25 419 4.61E-56 T 09-03-2017 UA74_RS21915 9d93f802f45422402049d83f84d9834f 421 Gene3D G3DSA:3.40.190.10 154 319 8.0E-16 T 09-03-2017 UA74_RS21915 9d93f802f45422402049d83f84d9834f 421 Pfam PF01547 Bacterial extracellular solute-binding protein 49 331 4.7E-24 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS21915 9d93f802f45422402049d83f84d9834f 421 Gene3D G3DSA:3.40.190.10 320 343 1.7E-25 T 09-03-2017 UA74_RS21915 9d93f802f45422402049d83f84d9834f 421 Gene3D G3DSA:3.40.190.10 11 144 1.7E-25 T 09-03-2017 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 SMART SM00421 152 209 1.4E-24 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 SUPERFAMILY SSF52172 1 133 7.54E-34 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 Pfam PF00072 Response regulator receiver domain 5 118 3.0E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.4E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.4E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.4E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 Gene3D G3DSA:3.40.50.2300 1 124 3.5E-36 T 09-03-2017 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 Gene3D G3DSA:1.10.10.10 125 215 1.2E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.1E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 SUPERFAMILY SSF46894 144 215 2.04E-23 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS06160 578c31840d518abfcd869a94408b2cd2 216 SMART SM00448 3 118 1.9E-30 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS28405 6fc06a32468a7f4952d416abbb2ac62a 347 Pfam PF00294 pfkB family carbohydrate kinase 2 336 5.3E-43 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS28405 6fc06a32468a7f4952d416abbb2ac62a 347 SUPERFAMILY SSF53613 2 337 8.57E-58 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS28405 6fc06a32468a7f4952d416abbb2ac62a 347 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 278 291 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS28405 6fc06a32468a7f4952d416abbb2ac62a 347 Gene3D G3DSA:3.40.1190.20 2 341 1.1E-62 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS00920 26524714f529f8573e326a0eb42e627a 268 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 266 3.4E-7 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS00920 26524714f529f8573e326a0eb42e627a 268 Gene3D G3DSA:3.40.50.300 4 256 1.9E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00920 26524714f529f8573e326a0eb42e627a 268 SMART SM00382 33 232 1.6E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00920 26524714f529f8573e326a0eb42e627a 268 Pfam PF00005 ABC transporter 25 183 3.2E-22 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00920 26524714f529f8573e326a0eb42e627a 268 SUPERFAMILY SSF52540 4 254 6.27E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05850 d0f7fc6b2e5fab1c0471cacec5dae810 260 SUPERFAMILY SSF53474 10 253 2.92E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05850 d0f7fc6b2e5fab1c0471cacec5dae810 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 7.5E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05850 d0f7fc6b2e5fab1c0471cacec5dae810 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 7.5E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05850 d0f7fc6b2e5fab1c0471cacec5dae810 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 7.5E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05850 d0f7fc6b2e5fab1c0471cacec5dae810 260 Pfam PF00561 alpha/beta hydrolase fold 19 239 7.8E-15 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05850 d0f7fc6b2e5fab1c0471cacec5dae810 260 Gene3D G3DSA:3.40.50.1820 12 252 1.6E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 753 1322 8.2E-233 T 09-03-2017 IPR023837 EccCb-like, Actinobacteria UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 Pfam PF01580 FtsK/SpoIIIE family 813 1039 4.3E-50 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 Pfam PF01580 FtsK/SpoIIIE family 447 576 1.6E-22 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 Gene3D G3DSA:3.40.50.300 811 1012 1.0E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 Gene3D G3DSA:3.40.50.300 446 632 3.0E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 SUPERFAMILY SSF52540 771 1021 2.84E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 697 1.5E-278 T 09-03-2017 IPR023836 EccCa-like, Actinobacteria UA74_RS28240 0992cfb16a2022cf5317704b0b9fd911 1329 SUPERFAMILY SSF52540 440 660 5.62E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 SMART SM00382 39 247 2.0E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 SMART SM00382 384 548 9.1E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 Gene3D G3DSA:3.40.50.300 148 277 3.9E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 Gene3D G3DSA:3.40.50.300 23 114 3.9E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 Gene3D G3DSA:3.40.50.300 375 550 3.5E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 SUPERFAMILY SSF52540 378 550 3.17E-38 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 SUPERFAMILY SSF52540 25 247 6.92E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 Pfam PF00005 ABC transporter 376 503 9.5E-21 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 Pfam PF00005 ABC transporter 30 202 1.7E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS06660 687697e1d52873b284ce3c49953ad753 551 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13990 6ca5a3d92ce921a767c63b06d882919b 474 Gene3D G3DSA:1.10.260.40 7 63 6.0E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13990 6ca5a3d92ce921a767c63b06d882919b 474 SUPERFAMILY SSF47413 7 66 2.15E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13990 6ca5a3d92ce921a767c63b06d882919b 474 SMART SM00530 8 63 2.1E-10 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS13990 6ca5a3d92ce921a767c63b06d882919b 474 Pfam PF13560 Helix-turn-helix domain 7 66 6.7E-10 T 09-03-2017 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 PIRSF PIRSF000732 1 547 1.6E-137 T 09-03-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 Gene3D G3DSA:1.10.274.10 30 126 5.8E-16 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 SUPERFAMILY SSF52009 118 232 3.66E-27 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 Pfam PF00391 PEP-utilising enzyme, mobile domain 147 217 2.8E-21 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 243 513 2.6E-74 T 09-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 SUPERFAMILY SSF51621 239 518 1.54E-80 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 SUPERFAMILY SSF47831 29 136 5.23E-17 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 Gene3D G3DSA:3.50.30.10 127 234 2.4E-30 T 09-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 473 485 3.2E-19 T 09-03-2017 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 420 435 3.2E-19 T 09-03-2017 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 437 452 3.2E-19 T 09-03-2017 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 275 294 3.2E-19 T 09-03-2017 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 Gene3D G3DSA:3.20.20.60 242 540 1.8E-81 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 Pfam PF05524 PEP-utilising enzyme, N-terminal 2 119 4.2E-17 T 09-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 420 438 - T 09-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 UA74_RS30295 44e8735cacd7f35c09b6b75b97fae3fb 561 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 177 188 - T 09-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 207 5.9E-67 T 09-03-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 SUPERFAMILY SSF54782 216 304 2.62E-14 T 09-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 SUPERFAMILY SSF53850 3 211 8.47E-66 T 09-03-2017 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 226 243 5.4E-24 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 71 90 5.4E-24 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 5.4E-24 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 119 136 5.4E-24 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Gene3D G3DSA:3.40.190.10 106 194 8.8E-35 T 09-03-2017 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Gene3D G3DSA:3.30.160.40 217 304 1.9E-17 T 09-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 227 243 - T 09-03-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 223 299 3.2E-15 T 09-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Gene3D G3DSA:3.40.190.10 2 105 3.5E-35 T 09-03-2017 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 301 33.756 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 299 1.1E-89 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02305 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PIRSF PIRSF001438 1 310 3.9E-104 T 09-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS22600 efe533971900e5c56d2cdc53336c117a 130 SUPERFAMILY SSF46785 11 119 8.77E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22600 efe533971900e5c56d2cdc53336c117a 130 Pfam PF01638 HxlR-like helix-turn-helix 23 109 6.0E-24 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS22600 efe533971900e5c56d2cdc53336c117a 130 Gene3D G3DSA:1.10.10.10 7 122 1.6E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11085 80dfa7c7c24c89dc434bd8b8bf4148ee 86 Gene3D G3DSA:1.10.1200.10 4 82 8.5E-17 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS11085 80dfa7c7c24c89dc434bd8b8bf4148ee 86 SMART SM00823 Phosphopantetheine attachment site 6 81 0.0073 T 09-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS11085 80dfa7c7c24c89dc434bd8b8bf4148ee 86 SUPERFAMILY SSF47336 2 81 2.75E-14 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS11085 80dfa7c7c24c89dc434bd8b8bf4148ee 86 Pfam PF00550 Phosphopantetheine attachment site 7 77 2.9E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05595 f49de2b28e6e9c67cab2b8e259309ad0 199 SUPERFAMILY SSF53335 4 186 1.49E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05595 f49de2b28e6e9c67cab2b8e259309ad0 199 Gene3D G3DSA:3.40.50.150 4 188 7.8E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05595 f49de2b28e6e9c67cab2b8e259309ad0 199 Pfam PF08241 Methyltransferase domain 39 132 8.4E-21 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 160 6.5E-24 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF52540 13 234 6.27E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:2.40.30.10 233 331 3.5E-28 T 09-03-2017 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF54980 427 541 2.25E-27 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF50447 180 328 4.57E-31 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Pfam PF03144 Elongation factor Tu domain 2 247 317 2.7E-12 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF54980 330 416 1.25E-10 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Pfam PF00009 Elongation factor Tu GTP binding domain 16 223 1.9E-50 T 09-03-2017 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:2.40.50.250 511 605 8.4E-35 T 09-03-2017 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 16 626 4.3E-269 T 09-03-2017 IPR006298 GTP-binding protein TypA GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 SMART SM00838 424 512 0.0033 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 86 96 3.6E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 18 31 3.6E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.6E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 138 147 3.6E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 102 113 3.6E-16 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:3.40.50.300 13 232 1.3E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:3.30.70.240 431 509 3.1E-29 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:3.30.70.870 332 430 4.0E-33 T 09-03-2017 UA74_RS04395 4710cfba64ded89f7ef5da45b1d8a9b9 637 Pfam PF00679 Elongation factor G C-terminus 425 508 1.8E-21 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 Gene3D G3DSA:3.40.50.300 5 275 8.9E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 SUPERFAMILY SSF52540 6 270 7.82E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 Gene3D G3DSA:3.30.70.870 389 457 7.1E-7 T 09-03-2017 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 Pfam PF16658 Class II release factor RF3, C-terminal domain 381 506 7.0E-36 T 09-03-2017 IPR032090 Peptide chain release factor 3, C-terminal UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 518 8.7E-156 T 09-03-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 Pfam PF00009 Elongation factor Tu GTP binding domain 9 270 1.3E-48 T 09-03-2017 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 SUPERFAMILY SSF50447 255 382 1.01E-23 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 Gene3D G3DSA:2.40.30.10 286 380 3.2E-18 T 09-03-2017 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 PRINTS PR00315 GTP-binding elongation factor signature 11 24 2.7E-11 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 PRINTS PR00315 GTP-binding elongation factor signature 81 91 2.7E-11 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.7E-11 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 PRINTS PR00315 GTP-binding elongation factor signature 97 108 2.7E-11 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 PRINTS PR00315 GTP-binding elongation factor signature 61 69 2.7E-11 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 520 46.616 T 09-03-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 SUPERFAMILY SSF54980 387 460 1.98E-10 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS11245 a7a2108259620ece39ffb717c435b745 523 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 144 4.7E-21 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS08965 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Pfam PF00480 ROK family 85 393 1.8E-50 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS08965 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Gene3D G3DSA:1.10.10.10 11 78 4.5E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08965 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Gene3D G3DSA:3.30.420.40 79 220 8.1E-46 T 09-03-2017 UA74_RS08965 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 ProSitePatterns PS01125 ROK family signature. 216 243 - T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS08965 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Gene3D G3DSA:3.30.420.40 221 375 5.9E-40 T 09-03-2017 UA74_RS08965 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 SUPERFAMILY SSF53067 82 394 1.03E-48 T 09-03-2017 UA74_RS08965 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 SUPERFAMILY SSF46785 12 74 6.21E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 Pfam PF01225 Mur ligase family, catalytic domain 40 114 7.5E-9 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 Pfam PF02875 Mur ligase family, glutamate ligase domain 347 431 6.4E-19 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 Gene3D G3DSA:3.90.190.20 351 497 5.4E-48 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 SUPERFAMILY SSF53623 120 345 4.06E-62 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 Pfam PF08245 Mur ligase middle domain 129 327 5.5E-37 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 SUPERFAMILY SSF63418 34 118 9.42E-17 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 38 504 7.2E-136 T 09-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 SUPERFAMILY SSF53244 347 505 1.44E-43 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 15 504 31.278 T 09-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 Gene3D G3DSA:3.40.1190.10 120 350 6.2E-67 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS09700 e998ebf2556389c0be0537a5fc4e2f0f 513 Gene3D G3DSA:3.40.1390.10 34 118 8.1E-16 T 09-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 SUPERFAMILY SSF52540 267 476 1.5E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 SUPERFAMILY SSF52540 2 232 2.15E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 Gene3D G3DSA:3.40.50.300 1 235 2.0E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 Gene3D G3DSA:3.40.50.300 268 476 7.0E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 Pfam PF00005 ABC transporter 14 171 8.8E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 Pfam PF00005 ABC transporter 271 421 2.2E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 SMART SM00382 280 470 4.2E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS20795 41d176290df0fdb088745559f70c0b39 495 SMART SM00382 23 219 3.9E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS09725 544aa20b59a152c175a743e787bdb437 358 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 141 2.7E-37 T 09-03-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS09725 544aa20b59a152c175a743e787bdb437 358 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 356 30.189 T 09-03-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS09725 544aa20b59a152c175a743e787bdb437 358 SUPERFAMILY SSF53756 3 356 6.06E-94 T 09-03-2017 UA74_RS09725 544aa20b59a152c175a743e787bdb437 358 Gene3D G3DSA:3.40.50.2000 192 325 8.3E-5 T 09-03-2017 UA74_RS09725 544aa20b59a152c175a743e787bdb437 358 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 187 347 2.0E-34 T 09-03-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 UA74_RS09725 544aa20b59a152c175a743e787bdb437 358 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 2.1E-82 T 09-03-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS09725 544aa20b59a152c175a743e787bdb437 358 Gene3D G3DSA:3.40.50.2000 2 191 4.9E-59 T 09-03-2017 UA74_RS10350 201cbf07fc83366486a7b8c927884373 273 SUPERFAMILY SSF81301 14 130 8.18E-7 T 09-03-2017 UA74_RS10350 201cbf07fc83366486a7b8c927884373 273 Gene3D G3DSA:3.30.460.10 22 68 7.7E-6 T 09-03-2017 UA74_RS12595 5bd2e131f23313ac456918e334e25a95 310 SUPERFAMILY SSF52540 5 227 1.52E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12595 5bd2e131f23313ac456918e334e25a95 310 Gene3D G3DSA:3.40.50.300 4 230 7.7E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12595 5bd2e131f23313ac456918e334e25a95 310 SMART SM00382 34 212 4.7E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12595 5bd2e131f23313ac456918e334e25a95 310 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS12595 5bd2e131f23313ac456918e334e25a95 310 Pfam PF00005 ABC transporter 26 164 2.0E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS21745 09e74d8a112ef0647c3d156355b990be 284 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 43 115 7.5E-8 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS21745 09e74d8a112ef0647c3d156355b990be 284 SUPERFAMILY SSF75217 109 283 1.37E-38 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS21745 09e74d8a112ef0647c3d156355b990be 284 Gene3D G3DSA:3.30.1330.30 20 117 2.7E-23 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS21745 09e74d8a112ef0647c3d156355b990be 284 Pfam PF00588 SpoU rRNA Methylase family 132 276 4.3E-34 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_RS21745 09e74d8a112ef0647c3d156355b990be 284 SMART SM00967 43 121 1.6E-9 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS21745 09e74d8a112ef0647c3d156355b990be 284 Gene3D G3DSA:3.40.1280.10 128 282 3.8E-45 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS21745 09e74d8a112ef0647c3d156355b990be 284 SUPERFAMILY SSF55315 21 117 1.13E-16 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS03195 a82b0fd7943249f413071562859ac4a4 500 Pfam PF00990 Diguanylate cyclase, GGDEF domain 319 478 1.3E-37 T 09-03-2017 IPR000160 GGDEF domain UA74_RS03195 a82b0fd7943249f413071562859ac4a4 500 SUPERFAMILY SSF55073 324 481 1.57E-40 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS03195 a82b0fd7943249f413071562859ac4a4 500 Gene3D G3DSA:1.25.40.10 38 282 7.4E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03195 a82b0fd7943249f413071562859ac4a4 500 SMART SM00267 308 482 7.1E-44 T 09-03-2017 IPR000160 GGDEF domain UA74_RS03195 a82b0fd7943249f413071562859ac4a4 500 Gene3D G3DSA:3.30.70.270 321 481 2.2E-47 T 09-03-2017 UA74_RS03195 a82b0fd7943249f413071562859ac4a4 500 SUPERFAMILY SSF48452 153 251 2.22E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03195 a82b0fd7943249f413071562859ac4a4 500 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 317 482 1.2E-40 T 09-03-2017 IPR000160 GGDEF domain UA74_RS22265 96048133ae9d31e52d0fe8747b02eac9 501 Pfam PF08666 SAF domain 15 82 3.5E-10 T 09-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_RS22265 96048133ae9d31e52d0fe8747b02eac9 501 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 106 499 5.6E-154 T 09-03-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 UA74_RS22265 96048133ae9d31e52d0fe8747b02eac9 501 SMART SM00858 15 83 2.7E-14 T 09-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_RS00600 844cca8006176f6f582bb9c039723e58 387 SUPERFAMILY SSF52440 175 283 1.04E-33 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS00600 844cca8006176f6f582bb9c039723e58 387 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 385 3.9E-142 T 09-03-2017 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain UA74_RS00600 844cca8006176f6f582bb9c039723e58 387 SUPERFAMILY SSF56059 3 167 2.61E-71 T 09-03-2017 UA74_RS00600 844cca8006176f6f582bb9c039723e58 387 SUPERFAMILY SSF56059 270 384 2.61E-71 T 09-03-2017 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 271 287 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 498 515 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 70 95 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 414 432 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 474 489 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 181 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 144 162 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 438 456 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 301 320 8.0E-68 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 Pfam PF01019 Gamma-glutamyltranspeptidase 63 593 5.2E-147 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 SUPERFAMILY SSF56235 40 597 5.18E-152 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS24330 8db073318f93c3607cde7628de7c5c59 609 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 50 587 1.1E-122 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS13900 aa0ebb87f6f671dd85cebcc18264b03b 211 Pfam PF01930 Domain of unknown function DUF83 15 191 6.2E-25 T 09-03-2017 IPR022765 Dna2/Cas4, domain of unknown function DUF83 UA74_RS13900 aa0ebb87f6f671dd85cebcc18264b03b 211 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 13 191 3.7E-26 T 09-03-2017 IPR013343 CRISPR-associated protein Cas4 UA74_RS19110 457a199dc9545a84520b52786ec2d06d 489 Pfam PF13460 NAD(P)H-binding 7 114 2.6E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19110 457a199dc9545a84520b52786ec2d06d 489 SUPERFAMILY SSF55961 337 482 9.7E-10 T 09-03-2017 UA74_RS19110 457a199dc9545a84520b52786ec2d06d 489 Pfam PF11066 Protein of unknown function (DUF2867) 328 472 3.7E-41 T 09-03-2017 IPR021295 Protein of unknown function DUF2867 UA74_RS19110 457a199dc9545a84520b52786ec2d06d 489 Gene3D G3DSA:3.40.50.720 2 219 1.4E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19110 457a199dc9545a84520b52786ec2d06d 489 SUPERFAMILY SSF51735 2 280 1.12E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05775 838988aef848195b7132cd283f9d7428 527 SUPERFAMILY SSF48452 104 266 3.79E-32 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05775 838988aef848195b7132cd283f9d7428 527 SMART SM01043 108 250 5.6E-44 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS05775 838988aef848195b7132cd283f9d7428 527 PRINTS PR00364 Disease resistance protein signature 386 400 6.2E-6 T 09-03-2017 UA74_RS05775 838988aef848195b7132cd283f9d7428 527 PRINTS PR00364 Disease resistance protein signature 308 323 6.2E-6 T 09-03-2017 UA74_RS05775 838988aef848195b7132cd283f9d7428 527 PRINTS PR00364 Disease resistance protein signature 474 488 6.2E-6 T 09-03-2017 UA74_RS05775 838988aef848195b7132cd283f9d7428 527 SMART SM00862 19 101 3.8E-11 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS05775 838988aef848195b7132cd283f9d7428 527 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 101 7.6E-10 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS05775 838988aef848195b7132cd283f9d7428 527 Gene3D G3DSA:1.10.10.10 14 104 1.0E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05775 838988aef848195b7132cd283f9d7428 527 SMART SM00382 305 445 7.8E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS05775 838988aef848195b7132cd283f9d7428 527 Pfam PF03704 Bacterial transcriptional activator domain 108 250 1.4E-39 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS05775 838988aef848195b7132cd283f9d7428 527 SUPERFAMILY SSF52540 275 505 1.85E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05775 838988aef848195b7132cd283f9d7428 527 SUPERFAMILY SSF46894 5 101 5.1E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS05775 838988aef848195b7132cd283f9d7428 527 Gene3D G3DSA:3.40.50.300 292 404 7.1E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Gene3D G3DSA:3.40.50.1240 155 302 1.6E-22 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 SUPERFAMILY SSF55811 12 150 1.62E-29 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Pfam PF00293 NUDIX domain 14 148 1.9E-22 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Gene3D G3DSA:3.90.79.10 11 150 2.4E-32 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 158 253 4.6E-12 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 SUPERFAMILY SSF53254 156 308 2.57E-20 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 SMART SM00855 157 271 6.9E-10 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 PRINTS PR00502 NUDIX hydrolase family signature 46 60 8.0E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS26025 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 PRINTS PR00502 NUDIX hydrolase family signature 60 75 8.0E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS17405 ef1df61255e54acbe90a923efe4f6e50 223 SUPERFAMILY SSF46689 15 81 1.85E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17405 ef1df61255e54acbe90a923efe4f6e50 223 SUPERFAMILY SSF48498 89 204 5.4E-24 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS17405 ef1df61255e54acbe90a923efe4f6e50 223 Gene3D G3DSA:1.10.10.60 11 67 7.7E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17405 ef1df61255e54acbe90a923efe4f6e50 223 Gene3D G3DSA:1.10.357.10 68 205 7.2E-42 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS13555 07b43fea1bccfaad1aef2d97f8da0100 394 Pfam PF02040 Arsenical pump membrane protein 47 391 1.4E-18 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_RS13555 07b43fea1bccfaad1aef2d97f8da0100 394 PRINTS PR00758 Arsenical pump membrane protein signature 333 358 4.2E-14 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_RS13555 07b43fea1bccfaad1aef2d97f8da0100 394 PRINTS PR00758 Arsenical pump membrane protein signature 158 181 4.2E-14 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_RS13555 07b43fea1bccfaad1aef2d97f8da0100 394 PRINTS PR00758 Arsenical pump membrane protein signature 366 390 4.2E-14 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_RS13555 07b43fea1bccfaad1aef2d97f8da0100 394 PRINTS PR00758 Arsenical pump membrane protein signature 85 109 4.2E-14 T 09-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_RS07530 c8720cbef7199eb11733a7084ee49c04 294 Gene3D G3DSA:1.10.260.40 7 70 1.6E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS07530 c8720cbef7199eb11733a7084ee49c04 294 SMART SM00530 19 74 4.7E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS07530 c8720cbef7199eb11733a7084ee49c04 294 Pfam PF13560 Helix-turn-helix domain 15 77 2.7E-11 T 09-03-2017 UA74_RS07530 c8720cbef7199eb11733a7084ee49c04 294 SUPERFAMILY SSF47413 14 70 1.74E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 SUPERFAMILY SSF55816 365 572 5.49E-30 T 09-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 SUPERFAMILY SSF56300 20 356 5.9E-46 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 PRINTS PR01607 Apyrase family signature 20 38 5.8E-9 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 PRINTS PR01607 Apyrase family signature 432 455 5.8E-9 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 PRINTS PR01607 Apyrase family signature 247 270 5.8E-9 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 PRINTS PR01607 Apyrase family signature 526 545 5.8E-9 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 PRINTS PR01607 Apyrase family signature 295 315 5.8E-9 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 PRINTS PR01607 Apyrase family signature 227 244 5.8E-9 T 09-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 ProSitePatterns PS00786 5'-nucleotidase signature 2. 123 134 - T 09-03-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 Gene3D G3DSA:3.90.780.10 366 578 5.4E-37 T 09-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 Pfam PF02872 5'-nucleotidase, C-terminal domain 366 549 5.2E-28 T 09-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_RS05015 ff56cee54a564aa53eb73ed7debe99a5 595 Gene3D G3DSA:3.60.21.10 18 360 1.9E-55 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS27345 abb3bf247471f58df3ec778b3193a2ab 255 Pfam PF01061 ABC-2 type transporter 15 222 3.5E-18 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS27345 abb3bf247471f58df3ec778b3193a2ab 255 PIRSF PIRSF006648 1 254 1.2E-19 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS15135 e7cee4d3580c7d3aa1b24912f54c942b 125 SUPERFAMILY SSF54593 10 121 2.95E-19 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15135 e7cee4d3580c7d3aa1b24912f54c942b 125 Gene3D G3DSA:3.10.180.10 15 123 4.5E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15135 e7cee4d3580c7d3aa1b24912f54c942b 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 119 9.5E-8 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS26895 9c188cd675ab85b49ebbe8d6f6525703 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 6.6E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26895 9c188cd675ab85b49ebbe8d6f6525703 333 Gene3D G3DSA:3.90.25.10 184 322 4.2E-50 T 09-03-2017 UA74_RS26895 9c188cd675ab85b49ebbe8d6f6525703 333 SUPERFAMILY SSF51735 1 319 2.69E-97 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26895 9c188cd675ab85b49ebbe8d6f6525703 333 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS26895 9c188cd675ab85b49ebbe8d6f6525703 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 321 7.2E-133 T 09-03-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 UA74_RS26895 9c188cd675ab85b49ebbe8d6f6525703 333 Gene3D G3DSA:3.40.50.720 1 183 1.5E-65 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14705 79a0c394c5626c1da72a375a9483d569 226 Pfam PF12833 Helix-turn-helix domain 149 225 4.0E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS14705 79a0c394c5626c1da72a375a9483d569 226 SMART SM00342 141 223 3.7E-13 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS14705 79a0c394c5626c1da72a375a9483d569 226 Gene3D G3DSA:1.10.10.60 179 226 2.1E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14705 79a0c394c5626c1da72a375a9483d569 226 Gene3D G3DSA:1.10.10.60 128 178 9.7E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05910 a06864daec5cddfa9fa2f80805786349 399 Pfam PF04027 Domain of unknown function (DUF371) 26 144 7.3E-15 T 09-03-2017 IPR007171 Protein of unknown function DUF371 UA74_RS05910 a06864daec5cddfa9fa2f80805786349 399 Gene3D G3DSA:2.60.120.630 22 145 5.9E-26 T 09-03-2017 IPR023131 Mth639-like domain UA74_RS17870 e13878d7c667f53a77b0dec0f35df5f5 291 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 33 268 2.7E-21 T 09-03-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 UA74_RS17870 e13878d7c667f53a77b0dec0f35df5f5 291 SUPERFAMILY SSF56112 40 271 1.53E-29 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS17870 e13878d7c667f53a77b0dec0f35df5f5 291 Gene3D G3DSA:3.90.1200.10 122 233 8.0E-11 T 09-03-2017 UA74_RS03000 8ebb3252d70325de7fc93113368297d0 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.73 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03000 8ebb3252d70325de7fc93113368297d0 132 Gene3D G3DSA:3.30.1370.30 2 72 1.1E-27 T 09-03-2017 UA74_RS03000 8ebb3252d70325de7fc93113368297d0 132 Pfam PF00410 Ribosomal protein S8 5 132 9.5E-48 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03000 8ebb3252d70325de7fc93113368297d0 132 Gene3D G3DSA:3.30.1490.10 76 132 4.7E-26 T 09-03-2017 UA74_RS03000 8ebb3252d70325de7fc93113368297d0 132 SUPERFAMILY SSF56047 3 132 3.14E-43 T 09-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS06120 4e5539e511d7ae415f1c348123900a66 294 Pfam PF02517 CAAX protease self-immunity 182 281 6.6E-15 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 UA74_RS24245 80aa2805751e3701e98d9fcb394d09b1 229 Gene3D G3DSA:1.10.357.10 11 195 1.8E-34 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS24245 80aa2805751e3701e98d9fcb394d09b1 229 SUPERFAMILY SSF46689 9 79 7.48E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS24245 80aa2805751e3701e98d9fcb394d09b1 229 SUPERFAMILY SSF48498 86 175 1.65E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS24245 80aa2805751e3701e98d9fcb394d09b1 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.0E-17 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS24245 80aa2805751e3701e98d9fcb394d09b1 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 6.0E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS24245 80aa2805751e3701e98d9fcb394d09b1 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 6.0E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22180 5fbb24ee58be13b6f4e3a8c060164e3d 507 Pfam PF13810 Domain of unknown function (DUF4185) 47 350 3.9E-104 T 09-03-2017 IPR025442 Domain of unknown function DUF4185 UA74_RS22180 5fbb24ee58be13b6f4e3a8c060164e3d 507 Gene3D G3DSA:2.120.10.10 161 223 7.0E-6 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS22180 5fbb24ee58be13b6f4e3a8c060164e3d 507 Gene3D G3DSA:2.60.120.260 355 505 2.3E-9 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS22180 5fbb24ee58be13b6f4e3a8c060164e3d 507 SUPERFAMILY SSF50939 168 224 3.6E-5 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 Gene3D G3DSA:1.10.10.10 3 67 3.9E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 SUPERFAMILY SSF48008 73 201 1.52E-25 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.2E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 6.7E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 6.7E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 SMART SM00345 8 66 9.6E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 SMART SM00895 76 198 3.0E-21 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 Pfam PF07729 FCD domain 76 197 1.4E-25 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 SUPERFAMILY SSF46785 3 70 1.65E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20210 5b3402c0faa91c27d1ebef45a3957120 208 Gene3D G3DSA:1.20.120.530 70 201 1.7E-26 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS02935 50757f47f457d013bb83f50391353b61 236 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 204 1.2E-68 T 09-03-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02935 50757f47f457d013bb83f50391353b61 236 Gene3D G3DSA:3.40.1370.10 59 203 2.4E-51 T 09-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 UA74_RS02935 50757f47f457d013bb83f50391353b61 236 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 10 209 32.496 T 09-03-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02935 50757f47f457d013bb83f50391353b61 236 SUPERFAMILY SSF52166 4 205 1.44E-72 T 09-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 UA74_RS02935 50757f47f457d013bb83f50391353b61 236 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 5.8E-63 T 09-03-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 UA74_RS10850 879d3d1bdf79fcdb7eaf9825042cac2f 411 SUPERFAMILY SSF140478 167 238 6.8E-5 T 09-03-2017 IPR023353 LemA-like domain UA74_RS10850 879d3d1bdf79fcdb7eaf9825042cac2f 411 SUPERFAMILY SSF55811 244 381 6.91E-19 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS10850 879d3d1bdf79fcdb7eaf9825042cac2f 411 Pfam PF00293 NUDIX domain 254 381 8.3E-17 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS10850 879d3d1bdf79fcdb7eaf9825042cac2f 411 ProSitePatterns PS00893 Nudix box signature. 290 311 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS10850 879d3d1bdf79fcdb7eaf9825042cac2f 411 Gene3D G3DSA:1.20.1440.20 146 244 2.6E-8 T 09-03-2017 IPR023353 LemA-like domain UA74_RS10850 879d3d1bdf79fcdb7eaf9825042cac2f 411 Gene3D G3DSA:1.20.1440.20 18 82 2.6E-8 T 09-03-2017 IPR023353 LemA-like domain UA74_RS10850 879d3d1bdf79fcdb7eaf9825042cac2f 411 Gene3D G3DSA:3.90.79.10 254 383 7.9E-21 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS29680 04a2a783648dc518070bdf81298df4dd 466 Gene3D G3DSA:1.10.45.10 423 462 7.9E-12 T 09-03-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 UA74_RS29680 04a2a783648dc518070bdf81298df4dd 466 SUPERFAMILY SSF56176 8 221 2.52E-77 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS29680 04a2a783648dc518070bdf81298df4dd 466 SUPERFAMILY SSF55103 195 462 1.19E-55 T 09-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UA74_RS29680 04a2a783648dc518070bdf81298df4dd 466 Gene3D G3DSA:3.30.43.10 7 99 1.2E-25 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS29680 04a2a783648dc518070bdf81298df4dd 466 Gene3D G3DSA:3.30.465.10 101 221 9.2E-48 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS29680 04a2a783648dc518070bdf81298df4dd 466 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 461 4.0E-59 T 09-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 UA74_RS29680 04a2a783648dc518070bdf81298df4dd 466 Pfam PF01565 FAD binding domain 45 184 2.2E-42 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS10715 8c6ebe89df64a5d8fbf46e03b95bc45a 711 Pfam PF01061 ABC-2 type transporter 519 665 2.7E-10 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS10715 8c6ebe89df64a5d8fbf46e03b95bc45a 711 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 492 698 5.1E-52 T 09-03-2017 IPR017501 Phage infection protein, YhgE, C-terminal UA74_RS10715 8c6ebe89df64a5d8fbf46e03b95bc45a 711 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 1.6E-42 T 09-03-2017 IPR017500 Phage infection protein, YhgE, N-terminal UA74_RS06840 034f5e5a38abd9ae897c71f51be9c715 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 282 5.6E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS06840 034f5e5a38abd9ae897c71f51be9c715 286 Gene3D G3DSA:1.10.3720.10 47 281 1.3E-61 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS06840 034f5e5a38abd9ae897c71f51be9c715 286 SUPERFAMILY SSF161098 41 273 1.7E-61 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22920 4533a35f048135fa6421400696638d93 227 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 8 198 2.3E-17 T 09-03-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 UA74_RS22920 4533a35f048135fa6421400696638d93 227 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 8 210 1.9E-37 T 09-03-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial UA74_RS22920 4533a35f048135fa6421400696638d93 227 Gene3D G3DSA:3.40.50.1000 102 223 1.8E-31 T 09-03-2017 IPR023214 HAD-like domain UA74_RS22920 4533a35f048135fa6421400696638d93 227 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 196 7.1E-25 T 09-03-2017 UA74_RS22920 4533a35f048135fa6421400696638d93 227 SUPERFAMILY SSF56784 4 219 8.26E-23 T 09-03-2017 IPR023214 HAD-like domain UA74_RS27385 abb9c25dc9f1bf7084ce16bdc764336f 182 Pfam PF01899 Na+/H+ ion antiporter subunit 19 162 2.8E-26 T 09-03-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 UA74_RS08390 7affd8a65a3f8e1a7f07d825b8a9473c 326 Pfam PF06144 DNA polymerase III, delta subunit 13 174 7.8E-7 T 09-03-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 UA74_RS08390 7affd8a65a3f8e1a7f07d825b8a9473c 326 Gene3D G3DSA:1.10.8.60 137 220 5.7E-6 T 09-03-2017 UA74_RS08390 7affd8a65a3f8e1a7f07d825b8a9473c 326 SUPERFAMILY SSF52540 7 182 7.17E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08390 7affd8a65a3f8e1a7f07d825b8a9473c 326 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 9 317 1.1E-28 T 09-03-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 UA74_RS08390 7affd8a65a3f8e1a7f07d825b8a9473c 326 SUPERFAMILY SSF48019 203 317 1.12E-11 T 09-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UA74_RS08390 7affd8a65a3f8e1a7f07d825b8a9473c 326 Gene3D G3DSA:3.40.50.300 9 123 2.5E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22765 8df55aaa868508682c69151cbf0925dc 367 SUPERFAMILY SSF53597 170 364 1.83E-25 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS22765 8df55aaa868508682c69151cbf0925dc 367 Gene3D G3DSA:3.40.430.10 169 366 3.2E-29 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS22765 8df55aaa868508682c69151cbf0925dc 367 SUPERFAMILY SSF55961 14 156 1.45E-36 T 09-03-2017 UA74_RS22765 8df55aaa868508682c69151cbf0925dc 367 Pfam PF01872 RibD C-terminal domain 170 356 8.9E-21 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS22765 8df55aaa868508682c69151cbf0925dc 367 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 156 1.0E-18 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS22765 8df55aaa868508682c69151cbf0925dc 367 Gene3D G3DSA:3.30.530.20 7 156 6.0E-39 T 09-03-2017 IPR023393 START-like domain UA74_RS08305 df6e3776672a19c804142f73bbd39b74 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 7.3E-26 T 09-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08305 df6e3776672a19c804142f73bbd39b74 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 1.2E-34 T 09-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08305 df6e3776672a19c804142f73bbd39b74 103 SUPERFAMILY SSF141091 1 100 1.96E-32 T 09-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS08305 df6e3776672a19c804142f73bbd39b74 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 09-03-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08305 df6e3776672a19c804142f73bbd39b74 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 22.894 T 09-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS27960 ca58914dad841173d9c35b2ce2588c25 247 SUPERFAMILY SSF102588 12 242 7.98E-50 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS27960 ca58914dad841173d9c35b2ce2588c25 247 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 143 2.4E-32 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_RS27960 ca58914dad841173d9c35b2ce2588c25 247 Gene3D G3DSA:3.40.50.10320 11 245 1.2E-58 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS27170 dc2c610b31bb51add4a2ab67bbb7726c 272 Pfam PF14011 EspG family 13 255 1.5E-59 T 09-03-2017 IPR025734 EspG family UA74_RS29200 b9c6945e1ba410bd6f671aefe7a01012 433 Pfam PF00589 Phage integrase family 230 406 2.9E-12 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS29200 b9c6945e1ba410bd6f671aefe7a01012 433 Gene3D G3DSA:1.10.150.130 70 133 3.1E-11 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS29200 b9c6945e1ba410bd6f671aefe7a01012 433 Gene3D G3DSA:1.10.150.130 166 201 3.1E-11 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS29200 b9c6945e1ba410bd6f671aefe7a01012 433 SUPERFAMILY SSF56349 291 411 3.24E-41 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS29200 b9c6945e1ba410bd6f671aefe7a01012 433 SUPERFAMILY SSF56349 161 257 3.24E-41 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS29200 b9c6945e1ba410bd6f671aefe7a01012 433 SUPERFAMILY SSF56349 70 128 3.24E-41 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS29200 b9c6945e1ba410bd6f671aefe7a01012 433 Gene3D G3DSA:1.10.443.10 207 417 2.3E-23 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS14755 4d08870b553963d34efb4b4294b1f135 273 SUPERFAMILY SSF53474 12 272 3.93E-51 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14755 4d08870b553963d34efb4b4294b1f135 273 Gene3D G3DSA:3.40.50.1820 17 272 3.8E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14755 4d08870b553963d34efb4b4294b1f135 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.7E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS14755 4d08870b553963d34efb4b4294b1f135 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.7E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS14755 4d08870b553963d34efb4b4294b1f135 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 1.7E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS14755 4d08870b553963d34efb4b4294b1f135 273 Pfam PF00561 alpha/beta hydrolase fold 27 260 2.5E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22495 14567f5ef24a7e413b6b93790f9cb893 297 Gene3D G3DSA:3.40.50.720 12 163 3.3E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22495 14567f5ef24a7e413b6b93790f9cb893 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 162 1.5E-17 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS22495 14567f5ef24a7e413b6b93790f9cb893 297 PIRSF PIRSF000103 7 297 1.1E-26 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_RS22495 14567f5ef24a7e413b6b93790f9cb893 297 SUPERFAMILY SSF51735 13 161 1.1E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10050 6a4c1d25f696e8c6721a22c822ba609d 257 Gene3D G3DSA:3.20.20.70 6 257 3.4E-100 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS10050 6a4c1d25f696e8c6721a22c822ba609d 257 Pfam PF00977 Histidine biosynthesis protein 6 240 4.1E-84 T 09-03-2017 IPR006062 Histidine biosynthesis GO:0000105 UA74_RS10050 6a4c1d25f696e8c6721a22c822ba609d 257 SUPERFAMILY SSF51366 5 257 1.02E-77 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 UA74_RS10050 6a4c1d25f696e8c6721a22c822ba609d 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 257 46.995 T 09-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UA74_RS10050 6a4c1d25f696e8c6721a22c822ba609d 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 4 257 1.6E-107 T 09-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UA74_RS24190 d517f9b4d5294102e0c0c1659d33a8a8 200 Gene3D G3DSA:1.10.357.10 12 199 1.3E-26 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS24190 d517f9b4d5294102e0c0c1659d33a8a8 200 SUPERFAMILY SSF46689 3 80 7.7E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13350 a295416a7c128050303673716c989921 602 Gene3D G3DSA:3.40.50.300 371 591 2.3E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13350 a295416a7c128050303673716c989921 602 SMART SM00382 386 572 2.1E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13350 a295416a7c128050303673716c989921 602 SUPERFAMILY SSF90123 24 330 2.88E-53 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13350 a295416a7c128050303673716c989921 602 Gene3D G3DSA:1.20.1560.10 24 327 4.4E-54 T 09-03-2017 UA74_RS13350 a295416a7c128050303673716c989921 602 SUPERFAMILY SSF52540 369 595 1.55E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13350 a295416a7c128050303673716c989921 602 Pfam PF00005 ABC transporter 377 525 2.8E-21 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13350 a295416a7c128050303673716c989921 602 Pfam PF00664 ABC transporter transmembrane region 27 295 2.8E-32 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS14250 df5c99dc4bb99ac983eded3421feee93 268 SUPERFAMILY SSF51679 4 257 1.2E-47 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS14250 df5c99dc4bb99ac983eded3421feee93 268 Gene3D G3DSA:3.20.20.30 5 241 7.4E-52 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS14250 df5c99dc4bb99ac983eded3421feee93 268 Pfam PF00296 Luciferase-like monooxygenase 6 240 1.4E-42 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS14105 470a74049e94c12c287abc9e26867e00 188 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 180 1.3E-79 T 09-03-2017 IPR021441 Protein of unknown function DUF3090 UA74_RS14105 470a74049e94c12c287abc9e26867e00 188 Pfam PF11290 Protein of unknown function (DUF3090) 6 176 1.7E-69 T 09-03-2017 IPR021441 Protein of unknown function DUF3090 UA74_RS05605 9625059ec22a58f3ffa3d1abb38d7ea1 476 Gene3D G3DSA:3.30.465.10 101 220 2.2E-40 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS05605 9625059ec22a58f3ffa3d1abb38d7ea1 476 Pfam PF01565 FAD binding domain 45 182 1.6E-37 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS05605 9625059ec22a58f3ffa3d1abb38d7ea1 476 Gene3D G3DSA:1.10.45.10 433 472 2.7E-11 T 09-03-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 UA74_RS05605 9625059ec22a58f3ffa3d1abb38d7ea1 476 Gene3D G3DSA:3.30.43.10 2 99 2.1E-23 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS05605 9625059ec22a58f3ffa3d1abb38d7ea1 476 SUPERFAMILY SSF56176 8 220 3.27E-76 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS05605 9625059ec22a58f3ffa3d1abb38d7ea1 476 Pfam PF02913 FAD linked oxidases, C-terminal domain 224 472 6.3E-50 T 09-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 UA74_RS05605 9625059ec22a58f3ffa3d1abb38d7ea1 476 SUPERFAMILY SSF55103 225 474 1.31E-55 T 09-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UA74_RS07855 1faad53b27dc86730453ada73518d682 265 SUPERFAMILY SSF53448 5 223 4.22E-22 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS07855 1faad53b27dc86730453ada73518d682 265 Pfam PF13641 Glycosyltransferase like family 2 5 216 3.1E-8 T 09-03-2017 UA74_RS07855 1faad53b27dc86730453ada73518d682 265 Gene3D G3DSA:3.90.550.10 5 210 5.7E-13 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 SMART SM00322 59 124 4.9E-7 T 09-03-2017 IPR004087 K Homology domain GO:0003676 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 Pfam PF07650 KH domain 37 109 9.1E-18 T 09-03-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.814 T 09-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 SUPERFAMILY SSF54821 109 206 4.19E-35 T 09-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 09-03-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 8.3E-94 T 09-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 5.0E-36 T 09-03-2017 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 SUPERFAMILY SSF54814 2 105 5.76E-37 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 Gene3D G3DSA:3.30.300.20 17 106 1.2E-33 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS02960 5d19069f22c0e2ce883a57493271eef8 280 Gene3D G3DSA:3.30.1140.32 109 206 5.9E-41 T 09-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS15695 251e0788836d67f920a637644f3782b9 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 266 17.407 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UA74_RS15695 251e0788836d67f920a637644f3782b9 274 Pfam PF02673 Bacitracin resistance protein BacA 3 261 1.5E-74 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UA74_RS15695 251e0788836d67f920a637644f3782b9 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 3 259 1.8E-84 T 09-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 Gene3D G3DSA:3.40.50.300 504 625 9.5E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 Gene3D G3DSA:3.40.50.300 275 465 1.8E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 Pfam PF00270 DEAD/DEAH box helicase 276 462 4.0E-5 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 276 625 1.2E-58 T 09-03-2017 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 SUPERFAMILY SSF52540 276 329 1.43E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 SUPERFAMILY SSF52540 369 624 1.43E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 27 234 2.7E-18 T 09-03-2017 IPR006483 CRISPR-associated Cas3-HD domain UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 SUPERFAMILY SSF109604 30 129 2.63E-6 T 09-03-2017 UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 SMART SM00487 259 489 8.4E-6 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS15925 f70da360a1aae71069c3533ce668a7db 809 SMART SM00490 531 616 1.5E-4 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS28540 01ac8b0dd2f23ab8642716ec814a6e62 128 PRINTS PR00050 Cold shock protein signature 4 19 2.9E-12 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS28540 01ac8b0dd2f23ab8642716ec814a6e62 128 PRINTS PR00050 Cold shock protein signature 38 56 2.9E-12 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS28540 01ac8b0dd2f23ab8642716ec814a6e62 128 PRINTS PR00050 Cold shock protein signature 24 33 2.9E-12 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS28540 01ac8b0dd2f23ab8642716ec814a6e62 128 SMART SM00357 3 65 2.5E-22 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 UA74_RS28540 01ac8b0dd2f23ab8642716ec814a6e62 128 Gene3D G3DSA:2.40.50.140 3 68 1.4E-22 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS28540 01ac8b0dd2f23ab8642716ec814a6e62 128 Pfam PF00313 'Cold-shock' DNA-binding domain 4 63 4.4E-16 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS28540 01ac8b0dd2f23ab8642716ec814a6e62 128 SUPERFAMILY SSF50249 3 65 8.81E-17 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS12815 b28690cae27b36661bf9cf8a7d1eac02 155 Gene3D G3DSA:3.10.450.50 2 147 5.5E-31 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS12815 b28690cae27b36661bf9cf8a7d1eac02 155 SUPERFAMILY SSF54427 2 154 6.19E-37 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS12815 b28690cae27b36661bf9cf8a7d1eac02 155 Pfam PF00866 Ring hydroxylating beta subunit 16 148 1.1E-17 T 09-03-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 UA74_RS28300 4f392d01fabc1ba38d4d31223b4aea1a 267 SUPERFAMILY SSF53335 16 250 7.07E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28300 4f392d01fabc1ba38d4d31223b4aea1a 267 PIRSF PIRSF017393 1 264 4.7E-77 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS28300 4f392d01fabc1ba38d4d31223b4aea1a 267 Pfam PF04672 S-adenosyl methyltransferase 12 252 8.0E-70 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS28300 4f392d01fabc1ba38d4d31223b4aea1a 267 Gene3D G3DSA:3.40.50.150 2 266 2.9E-86 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04290 36102423135ef0c046fec7bf5fa8e1c1 442 Pfam PF13796 Putative sensor 38 216 2.6E-15 T 09-03-2017 IPR025828 Putative sensor domain UA74_RS04290 36102423135ef0c046fec7bf5fa8e1c1 442 SUPERFAMILY SSF55874 329 434 1.63E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS04290 36102423135ef0c046fec7bf5fa8e1c1 442 Pfam PF07730 Histidine kinase 244 312 3.1E-13 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS28550 8317b46e64313315d602d3e8ebc2fb7c 209 SUPERFAMILY SSF56784 5 200 3.45E-35 T 09-03-2017 IPR023214 HAD-like domain UA74_RS28550 8317b46e64313315d602d3e8ebc2fb7c 209 Gene3D G3DSA:3.40.50.1000 69 201 3.5E-24 T 09-03-2017 IPR023214 HAD-like domain UA74_RS28550 8317b46e64313315d602d3e8ebc2fb7c 209 Gene3D G3DSA:1.10.150.240 17 68 2.4E-8 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 UA74_RS28550 8317b46e64313315d602d3e8ebc2fb7c 209 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 157 2.0E-12 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 7.2E-7 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 409 428 7.2E-7 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 7.2E-7 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 7.2E-7 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 Pfam PF07690 Major Facilitator Superfamily 21 418 3.7E-52 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 427 2.6E-76 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 Gene3D G3DSA:1.20.1250.20 503 527 1.7E-22 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 Gene3D G3DSA:1.20.1250.20 17 197 1.1E-28 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 Gene3D G3DSA:1.20.1250.20 272 434 1.7E-22 T 09-03-2017 UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 SUPERFAMILY SSF103473 498 527 3.79E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 SUPERFAMILY SSF103473 7 206 3.79E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14035 35a5826b2c6ae0d252ee0ee197eab299 530 SUPERFAMILY SSF103473 257 428 3.79E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19540 ba66d006701231754fdd67b37bee3709 1222 SUPERFAMILY SSF53300 1056 1207 3.77E-20 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS19540 ba66d006701231754fdd67b37bee3709 1222 Pfam PF05762 VWA domain containing CoxE-like protein 995 1216 5.6E-57 T 09-03-2017 IPR008912 Uncharacterised protein family CoxE-like UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 SUPERFAMILY SSF46894 10 92 7.94E-12 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 92 8.6E-8 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 SUPERFAMILY SSF48452 94 259 3.46E-34 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 Pfam PF03704 Bacterial transcriptional activator domain 99 243 5.7E-39 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 Gene3D G3DSA:1.25.40.10 153 222 9.6E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 SMART SM01043 99 243 4.3E-44 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 Gene3D G3DSA:1.10.10.10 19 95 2.3E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17995 7ca1d9ed5573b5cc0d28d432ce61b127 286 SMART SM00862 18 92 9.9E-8 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS28130 08098b9521b153cb560289b2b0c364de 244 Gene3D G3DSA:3.30.420.40 2 137 7.7E-34 T 09-03-2017 UA74_RS28130 08098b9521b153cb560289b2b0c364de 244 Pfam PF00814 Glycoprotease family 38 168 1.1E-21 T 09-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28130 08098b9521b153cb560289b2b0c364de 244 SUPERFAMILY SSF53067 132 226 1.38E-9 T 09-03-2017 UA74_RS28130 08098b9521b153cb560289b2b0c364de 244 SUPERFAMILY SSF53067 3 107 2.04E-22 T 09-03-2017 UA74_RS28130 08098b9521b153cb560289b2b0c364de 244 Gene3D G3DSA:3.30.420.40 138 193 9.6E-9 T 09-03-2017 UA74_RS28130 08098b9521b153cb560289b2b0c364de 244 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 228 3.7E-51 T 09-03-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 UA74_RS01365 08704b608ad3873ef73257c813bf84da 273 Pfam PF00482 Type II secretion system (T2SS), protein F 101 224 1.0E-7 T 09-03-2017 IPR018076 Type II secretion system F domain UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 8.3E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 8.3E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 8.3E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 Pfam PF03466 LysR substrate binding domain 89 279 3.8E-10 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.8E-21 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 Gene3D G3DSA:3.40.190.10 91 173 2.8E-7 T 09-03-2017 UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 SUPERFAMILY SSF53850 89 283 9.23E-15 T 09-03-2017 UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 SUPERFAMILY SSF46785 5 88 1.96E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 Gene3D G3DSA:3.40.190.10 174 193 8.8E-4 T 09-03-2017 UA74_RS13765 ad90aebe9aeb26b099aef83dd1024a3a 297 Gene3D G3DSA:1.10.10.10 4 83 1.5E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 Gene3D G3DSA:3.40.50.150 559 625 1.3E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 Gene3D G3DSA:3.40.50.150 666 710 1.3E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 Gene3D G3DSA:3.40.50.150 865 944 1.3E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 605 619 2.7E-5 T 09-03-2017 UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 557 573 2.7E-5 T 09-03-2017 UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 872 884 2.7E-5 T 09-03-2017 UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 875 881 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 SUPERFAMILY SSF53335 548 629 4.67E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 SUPERFAMILY SSF53335 863 954 4.67E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 SUPERFAMILY SSF53335 658 712 4.67E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20645 942887ec30f4d57556711bb95c4b9cd5 1357 SUPERFAMILY SSF53335 283 430 4.67E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10555 dc1c4e045c61d300ab0406677b625be4 148 Gene3D G3DSA:3.30.530.20 1 145 1.4E-35 T 09-03-2017 IPR023393 START-like domain UA74_RS10555 dc1c4e045c61d300ab0406677b625be4 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 143 1.9E-20 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS10555 dc1c4e045c61d300ab0406677b625be4 148 SUPERFAMILY SSF55961 2 145 4.32E-33 T 09-03-2017 UA74_RS16235 81a720035881b4f38f178bf19aef3c56 146 Pfam PF01638 HxlR-like helix-turn-helix 20 119 2.8E-8 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS16235 81a720035881b4f38f178bf19aef3c56 146 Gene3D G3DSA:1.10.10.10 17 130 2.5E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16235 81a720035881b4f38f178bf19aef3c56 146 SUPERFAMILY SSF46785 15 121 5.26E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02740 f99f7da0e6df9416d0c046ddea12f5fe 291 Gene3D G3DSA:3.30.2010.10 60 150 1.2E-31 T 09-03-2017 UA74_RS02740 f99f7da0e6df9416d0c046ddea12f5fe 291 Pfam PF01435 Peptidase family M48 68 284 5.6E-37 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UA74_RS02740 f99f7da0e6df9416d0c046ddea12f5fe 291 Hamap MF_00188 Protease HtpX [htpX]. 7 284 27.354 T 09-03-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 Gene3D G3DSA:1.10.10.10 6 57 8.5E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 6.6E-14 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.5E-11 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.5E-11 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.5E-11 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 SUPERFAMILY SSF46785 7 66 4.29E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 SUPERFAMILY SSF54909 70 154 2.15E-11 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 SMART SM00344 7 116 2.9E-30 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 Gene3D G3DSA:3.30.70.920 59 148 2.6E-17 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS10205 5a1d1443a8535ae5ab1adc749ac9b427 160 Pfam PF01037 Lrp/AsnC ligand binding domain 75 146 3.2E-11 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS29835 9b6e25b2576d161b04c34213fdbb8605 278 SUPERFAMILY SSF140478 26 178 9.68E-47 T 09-03-2017 IPR023353 LemA-like domain UA74_RS29835 9b6e25b2576d161b04c34213fdbb8605 278 Pfam PF04011 LemA family 7 184 3.1E-61 T 09-03-2017 IPR007156 LemA UA74_RS29835 9b6e25b2576d161b04c34213fdbb8605 278 Gene3D G3DSA:1.20.1440.20 15 180 1.3E-54 T 09-03-2017 IPR023353 LemA-like domain UA74_RS16555 3038902a4915b121e2f2d9b52ebf4a2b 315 Pfam PF00005 ABC transporter 21 164 2.8E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16555 3038902a4915b121e2f2d9b52ebf4a2b 315 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 306 3.6E-96 T 09-03-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_RS16555 3038902a4915b121e2f2d9b52ebf4a2b 315 SUPERFAMILY SSF52540 3 228 3.13E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16555 3038902a4915b121e2f2d9b52ebf4a2b 315 SMART SM00382 30 221 9.5E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16555 3038902a4915b121e2f2d9b52ebf4a2b 315 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS16555 3038902a4915b121e2f2d9b52ebf4a2b 315 Gene3D G3DSA:3.40.50.300 2 234 1.5E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 SUPERFAMILY SSF52172 4 139 2.28E-30 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 SMART SM00448 5 120 2.6E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.4E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.6E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.6E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.6E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 Gene3D G3DSA:1.10.10.10 161 217 3.1E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 SUPERFAMILY SSF46894 151 218 1.36E-22 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 Pfam PF00072 Response regulator receiver domain 7 119 5.9E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 Gene3D G3DSA:3.40.50.2300 3 160 5.7E-37 T 09-03-2017 UA74_RS07570 66c5c757a7d44a925ff8cfd9fffb2c56 219 SMART SM00421 155 212 4.6E-26 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29635 66ea39a37ee23b138ebbebd3725e6272 137 Pfam PF11349 Protein of unknown function (DUF3151) 8 131 1.3E-58 T 09-03-2017 IPR014487 Protein of unknown function DUF3151 UA74_RS29635 66ea39a37ee23b138ebbebd3725e6272 137 PIRSF PIRSF017349 1 136 8.8E-60 T 09-03-2017 IPR014487 Protein of unknown function DUF3151 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 PRINTS PR00906 SecA protein signature 121 135 1.9E-39 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 PRINTS PR00906 SecA protein signature 415 428 1.9E-39 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 PRINTS PR00906 SecA protein signature 83 107 1.9E-39 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 PRINTS PR00906 SecA protein signature 378 395 1.9E-39 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 PRINTS PR00906 SecA protein signature 190 210 1.9E-39 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 PRINTS PR00906 SecA protein signature 341 363 1.9E-39 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 PRINTS PR00906 SecA protein signature 137 147 1.9E-39 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 SMART SM00957 5 404 8.1E-131 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Gene3D G3DSA:3.40.50.300 371 417 7.4E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Gene3D G3DSA:3.40.50.300 3 248 7.4E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 SUPERFAMILY SSF52540 419 580 4.85E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 745 15.161 T 09-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Gene3D G3DSA:1.10.3060.10 664 739 2.3E-25 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 SMART SM00958 252 360 3.1E-26 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Gene3D G3DSA:3.40.50.300 419 585 2.1E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Pfam PF07516 SecA Wing and Scaffold domain 654 738 1.1E-12 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 2 786 0.0 T 09-03-2017 IPR026389 Protein translocase subunit SecA, Actinobacteria-type UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 SUPERFAMILY SSF81767 258 368 3.79E-29 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 SUPERFAMILY SSF52540 533 571 1.25E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 SUPERFAMILY SSF52540 70 247 1.25E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Pfam PF01043 SecA preprotein cross-linking domain 257 360 1.1E-21 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 ProSitePatterns PS01312 SecA family signature. 502 517 - T 09-03-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 SUPERFAMILY SSF81886 601 746 5.1E-26 T 09-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Pfam PF07517 SecA DEAD-like domain 7 403 7.0E-81 T 09-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_RS19105 f92ad6d590dd0fa67dfa9380c11bff45 803 Gene3D G3DSA:3.90.1440.10 256 369 7.9E-32 T 09-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 UA74_RS18190 0e6191ebeae5383b041140a61636a846 216 Gene3D G3DSA:3.30.530.20 24 157 2.0E-31 T 09-03-2017 IPR023393 START-like domain UA74_RS18190 0e6191ebeae5383b041140a61636a846 216 SUPERFAMILY SSF55961 21 162 2.58E-32 T 09-03-2017 UA74_RS18190 0e6191ebeae5383b041140a61636a846 216 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 147 3.7E-16 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS01300 d64de7d4255b075e5fb7106826d9da71 263 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 09-03-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site UA74_RS01300 d64de7d4255b075e5fb7106826d9da71 263 Pfam PF00795 Carbon-nitrogen hydrolase 2 252 1.2E-31 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS01300 d64de7d4255b075e5fb7106826d9da71 263 Gene3D G3DSA:3.60.110.10 1 263 5.6E-62 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS01300 d64de7d4255b075e5fb7106826d9da71 263 SUPERFAMILY SSF56317 1 261 3.53E-58 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PIRSF PIRSF001100 2 325 6.2E-87 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 249 262 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 288 302 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 129 144 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 186 199 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 264 284 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 217 227 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 58 77 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 101 114 3.1E-45 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 Gene3D G3DSA:3.20.20.40 37 319 2.9E-93 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 SUPERFAMILY SSF51989 38 321 8.76E-89 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 106 122 - T 09-03-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 UA74_RS12250 8f15bcd4378381213ef6dd7dc0efc176 326 Pfam PF01341 Glycosyl hydrolases family 6 48 304 9.9E-66 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS20755 98ac95a33de2fc933722bb941d56d04a 404 Pfam PF01757 Acyltransferase family 21 352 1.6E-25 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS17850 4ecf79fc8709189861021de9dfafee9a 491 SUPERFAMILY SSF55874 282 356 2.56E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS17850 4ecf79fc8709189861021de9dfafee9a 491 Pfam PF07730 Histidine kinase 202 267 8.0E-16 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS17850 4ecf79fc8709189861021de9dfafee9a 491 Gene3D G3DSA:3.30.565.10 316 358 4.0E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS17850 4ecf79fc8709189861021de9dfafee9a 491 Gene3D G3DSA:3.30.565.10 422 486 4.0E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 430 1.8E-78 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 Gene3D G3DSA:1.20.1250.20 20 199 4.9E-30 T 09-03-2017 UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 SUPERFAMILY SSF103473 7 203 2.53E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 SUPERFAMILY SSF103473 257 428 2.53E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 SUPERFAMILY SSF103473 487 515 2.53E-65 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 Gene3D G3DSA:1.20.1250.20 278 429 8.2E-18 T 09-03-2017 UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 Gene3D G3DSA:1.20.1250.20 488 512 8.2E-18 T 09-03-2017 UA74_RS23225 b746d2c3c2efe656b511727f9c4d2a34 523 Pfam PF07690 Major Facilitator Superfamily 27 418 3.2E-49 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS13215 9eaad1f388beddedc0269d7d74c85dda 185 Gene3D G3DSA:2.40.128.110 14 182 6.6E-57 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like UA74_RS13215 9eaad1f388beddedc0269d7d74c85dda 185 Pfam PF04264 YceI-like domain 16 181 1.1E-44 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like UA74_RS13215 9eaad1f388beddedc0269d7d74c85dda 185 SUPERFAMILY SSF101874 14 182 7.85E-54 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like UA74_RS13215 9eaad1f388beddedc0269d7d74c85dda 185 SMART SM00867 15 182 1.2E-70 T 09-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 SMART SM01043 95 237 3.2E-36 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 Gene3D G3DSA:1.10.10.10 6 91 1.8E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 Pfam PF00486 Transcriptional regulatory protein, C terminal 19 86 9.5E-11 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 Pfam PF00931 NB-ARC domain 359 467 7.9E-8 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 Gene3D G3DSA:3.40.50.300 261 385 2.8E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 SMART SM00862 11 88 1.6E-8 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 Gene3D G3DSA:1.25.40.10 107 211 4.4E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 SUPERFAMILY SSF46894 2 88 3.4E-15 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 Pfam PF03704 Bacterial transcriptional activator domain 96 237 4.2E-32 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 SUPERFAMILY SSF52540 280 475 2.44E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14885 ced497d3086dd0a6f50b63edc8e6d441 479 SUPERFAMILY SSF48452 96 256 2.28E-26 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SUPERFAMILY SSF110296 456 761 2.35E-40 T 09-03-2017 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SMART SM00637 783 878 1.6E-38 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Gene3D G3DSA:2.130.10.140 50 490 1.0E-83 T 09-03-2017 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Gene3D G3DSA:2.130.10.140 503 754 1.5E-37 T 09-03-2017 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SUPERFAMILY SSF49384 777 878 1.26E-31 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Pfam PF00553 Cellulose binding domain 783 880 5.6E-28 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Gene3D G3DSA:2.60.40.290 782 880 8.6E-35 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS19010 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SUPERFAMILY SSF110296 41 446 2.35E-81 T 09-03-2017 UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.4 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 1.4E-98 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 Gene3D G3DSA:1.10.10.200 1 79 3.0E-32 T 09-03-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 Gene3D G3DSA:3.30.70.980 138 205 1.7E-21 T 09-03-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 SUPERFAMILY SSF75625 3 246 1.44E-87 T 09-03-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 Gene3D G3DSA:3.30.1270.10 84 137 2.6E-40 T 09-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 Gene3D G3DSA:3.30.1270.10 213 248 2.6E-40 T 09-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS10900 4f70659380acdef76d1badbc97275d1b 250 Pfam PF01709 Transcriptional regulator 5 238 7.1E-86 T 09-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 Gene3D G3DSA:1.10.10.10 159 220 8.9E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 SUPERFAMILY SSF52172 15 135 3.27E-30 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 Pfam PF00072 Response regulator receiver domain 17 129 2.4E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 3.3E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 3.3E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 3.3E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 Gene3D G3DSA:3.40.50.2300 15 158 1.1E-35 T 09-03-2017 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 SMART SM00448 15 129 9.4E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 SMART SM00421 158 215 5.7E-25 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 SUPERFAMILY SSF46894 146 221 9.86E-23 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS09190 4bb8bd6a7320b81ee3b7cf0a9c753caa 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 2.3E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS04330 7e4e2765e193ffd3d3c5ca1b2535c733 220 Gene3D G3DSA:3.40.50.2000 103 209 1.0E-7 T 09-03-2017 UA74_RS04330 7e4e2765e193ffd3d3c5ca1b2535c733 220 SUPERFAMILY SSF53756 29 209 3.56E-16 T 09-03-2017 UA74_RS13165 ced498aab64a891257fa7e1f4bcf7973 267 Pfam PF12822 Protein of unknown function (DUF3816) 71 239 3.9E-16 T 09-03-2017 IPR024529 ECF transporter, substrate-specific component GO:0005215 UA74_RS13165 ced498aab64a891257fa7e1f4bcf7973 267 PIRSF PIRSF037395 1 261 9.3E-92 T 09-03-2017 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 UA74_RS14945 4ecdbadaf1f84af3c53834ba5acfe4a0 287 Pfam PF13460 NAD(P)H-binding 10 175 1.8E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14945 4ecdbadaf1f84af3c53834ba5acfe4a0 287 Gene3D G3DSA:3.40.50.720 4 212 3.3E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14945 4ecdbadaf1f84af3c53834ba5acfe4a0 287 SUPERFAMILY SSF51735 5 276 1.15E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 Gene3D G3DSA:2.40.10.10 23 108 8.3E-5 T 09-03-2017 UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF52540 247 409 1.61E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 Pfam PF13365 Trypsin-like peptidase domain 24 174 1.9E-8 T 09-03-2017 UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 Gene3D G3DSA:1.25.40.10 948 1272 1.2E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF50494 14 177 1.59E-14 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF48452 1096 1141 4.41E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF48452 1221 1273 4.41E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22545 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF48452 947 1038 4.41E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 17 345 3.3E-108 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 SUPERFAMILY SSF47648 12 79 8.77E-20 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 14 346 33.586 T 09-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 Pfam PF02885 Glycosyl transferase family, helical bundle domain 15 75 1.4E-19 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 Pfam PF00591 Glycosyl transferase family, a/b domain 83 336 3.6E-78 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 SUPERFAMILY SSF52418 81 343 6.8E-76 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 Gene3D G3DSA:3.40.1030.10 83 345 1.6E-94 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS25070 2bf9f852d2adf2fa52d64bfeda34068e 356 Gene3D G3DSA:1.20.970.10 15 77 1.8E-26 T 09-03-2017 UA74_RS18755 50a3c196594fd1bb1a36f3151c613f08 312 Pfam PF02779 Transketolase, pyrimidine binding domain 56 173 4.6E-16 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS18755 50a3c196594fd1bb1a36f3151c613f08 312 Gene3D G3DSA:3.40.50.920 187 307 3.8E-10 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS18755 50a3c196594fd1bb1a36f3151c613f08 312 Gene3D G3DSA:3.40.50.970 11 174 5.9E-22 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS18755 50a3c196594fd1bb1a36f3151c613f08 312 SMART SM00861 16 181 1.2E-14 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS18755 50a3c196594fd1bb1a36f3151c613f08 312 SUPERFAMILY SSF52922 187 307 2.49E-12 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS18755 50a3c196594fd1bb1a36f3151c613f08 312 SUPERFAMILY SSF52518 17 173 9.64E-29 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS08150 5bf3c4642505401fd3556704961a7ef3 110 SUPERFAMILY SSF56349 10 98 2.24E-13 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS08150 5bf3c4642505401fd3556704961a7ef3 110 Gene3D G3DSA:1.10.443.10 5 98 2.0E-14 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS08150 5bf3c4642505401fd3556704961a7ef3 110 Pfam PF00589 Phage integrase family 8 91 5.2E-7 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15605 2dd40af6ded555384d6f53b142799c22 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 38 265 1.2E-43 T 09-03-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 UA74_RS15605 2dd40af6ded555384d6f53b142799c22 277 Pfam PF05175 Methyltransferase small domain 108 188 3.3E-11 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 UA74_RS15605 2dd40af6ded555384d6f53b142799c22 277 Gene3D G3DSA:1.10.8.10 34 69 2.3E-6 T 09-03-2017 UA74_RS15605 2dd40af6ded555384d6f53b142799c22 277 Gene3D G3DSA:3.40.50.150 70 265 7.7E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15605 2dd40af6ded555384d6f53b142799c22 277 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 11 272 1.1E-121 T 09-03-2017 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase UA74_RS15605 2dd40af6ded555384d6f53b142799c22 277 SUPERFAMILY SSF53335 47 239 3.29E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15255 98af1eabc5128acf597c656d43fd03e4 427 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 286 372 2.8E-9 T 09-03-2017 IPR023885 4Fe4S-binding SPASM domain UA74_RS15255 98af1eabc5128acf597c656d43fd03e4 427 Pfam PF13353 4Fe-4S single cluster domain 60 173 1.9E-5 T 09-03-2017 UA74_RS15255 98af1eabc5128acf597c656d43fd03e4 427 SMART SM00729 52 261 9.8E-4 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS15255 98af1eabc5128acf597c656d43fd03e4 427 SUPERFAMILY SSF102114 56 361 2.49E-43 T 09-03-2017 UA74_RS15255 98af1eabc5128acf597c656d43fd03e4 427 Pfam PF13186 Iron-sulfur cluster-binding domain 287 352 2.3E-9 T 09-03-2017 IPR023885 4Fe4S-binding SPASM domain UA74_RS15255 98af1eabc5128acf597c656d43fd03e4 427 Gene3D G3DSA:3.20.20.70 54 368 5.1E-48 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS15255 98af1eabc5128acf597c656d43fd03e4 427 Pfam PF04055 Radical SAM superfamily 59 221 8.8E-16 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS01130 7398de3aba765ca7724cd15616a2a7d4 512 SUPERFAMILY SSF53474 179 346 8.03E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01130 7398de3aba765ca7724cd15616a2a7d4 512 SUPERFAMILY SSF53474 70 139 8.03E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01130 7398de3aba765ca7724cd15616a2a7d4 512 SUPERFAMILY SSF53474 408 482 8.03E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01130 7398de3aba765ca7724cd15616a2a7d4 512 Gene3D G3DSA:3.40.50.1820 378 497 2.0E-57 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01130 7398de3aba765ca7724cd15616a2a7d4 512 Gene3D G3DSA:3.40.50.1820 58 144 2.0E-57 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01130 7398de3aba765ca7724cd15616a2a7d4 512 Gene3D G3DSA:3.40.50.1820 189 313 2.0E-57 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01130 7398de3aba765ca7724cd15616a2a7d4 512 Pfam PF00561 alpha/beta hydrolase fold 93 484 1.5E-25 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS04195 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 Pfam PF02401 LytB protein 30 307 1.4E-90 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UA74_RS04195 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 28 311 37.299 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UA74_RS04195 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 30 308 4.2E-98 T 09-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 SUPERFAMILY SSF63380 2 87 1.53E-24 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 Gene3D G3DSA:2.40.30.20 104 196 9.5E-33 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 Gene3D G3DSA:2.40.30.20 5 103 4.7E-33 T 09-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 193 8.0E-64 T 09-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 PIRSF PIRSF000498 1 208 7.1E-73 T 09-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 SUPERFAMILY SSF63380 92 194 1.28E-33 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 Pfam PF00677 Lumazine binding domain 99 183 7.9E-24 T 09-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12395 85d072785edbd3f358cb055cf76714a9 211 Pfam PF00677 Lumazine binding domain 3 86 1.7E-21 T 09-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS22470 12a789502f92fc3b31d30c0dcdaa2f00 193 SUPERFAMILY SSF46785 36 107 2.15E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22470 12a789502f92fc3b31d30c0dcdaa2f00 193 Gene3D G3DSA:1.10.10.10 34 90 9.2E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22470 12a789502f92fc3b31d30c0dcdaa2f00 193 SMART SM00418 34 120 0.0015 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS22470 12a789502f92fc3b31d30c0dcdaa2f00 193 Pfam PF12840 Helix-turn-helix domain 37 89 1.0E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12530 6f311594da10cd0a25d8185a2ab77c12 651 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 74 365 1.4E-35 T 09-03-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 UA74_RS12530 6f311594da10cd0a25d8185a2ab77c12 651 SUPERFAMILY SSF55486 248 322 5.13E-6 T 09-03-2017 UA74_RS12530 6f311594da10cd0a25d8185a2ab77c12 651 Gene3D G3DSA:3.40.390.10 251 325 4.1E-7 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 4.2E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 SUPERFAMILY SSF46894 153 221 1.94E-18 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 Pfam PF00072 Response regulator receiver domain 10 121 3.8E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 SMART SM00421 163 220 5.6E-19 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 SMART SM00448 8 121 3.1E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 Gene3D G3DSA:1.10.10.10 130 221 2.3E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 Gene3D G3DSA:3.40.50.2300 4 129 4.2E-36 T 09-03-2017 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 3.0E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 3.0E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 3.0E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05400 eb996d84867768f3c99810b4dc70c14c 225 SUPERFAMILY SSF52172 7 134 9.11E-33 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 Gene3D G3DSA:2.130.10.10 394 680 6.1E-32 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 Gene3D G3DSA:2.130.10.10 91 350 8.0E-32 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 SUPERFAMILY SSF82171 407 667 1.02E-29 T 09-03-2017 UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 SUPERFAMILY SSF82171 131 291 1.02E-29 T 09-03-2017 UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 Pfam PF07676 WD40-like Beta Propeller Repeat 507 526 2.0E-5 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 Pfam PF07676 WD40-like Beta Propeller Repeat 627 649 0.22 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 Pfam PF07676 WD40-like Beta Propeller Repeat 166 198 3.2E-8 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 Pfam PF07676 WD40-like Beta Propeller Repeat 454 475 0.019 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS20915 293fc951edcbe14399be7bd9494c5a48 1055 Pfam PF07676 WD40-like Beta Propeller Repeat 569 587 0.014 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 09-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 397 1.3E-125 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 SUPERFAMILY SSF53901 12 273 1.68E-57 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Pfam PF02803 Thiolase, C-terminal domain 278 397 1.1E-36 T 09-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Gene3D G3DSA:3.40.47.10 197 275 2.8E-50 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Gene3D G3DSA:3.40.47.10 12 136 2.8E-50 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Gene3D G3DSA:3.40.47.10 280 398 1.2E-48 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Gene3D G3DSA:3.40.47.10 157 196 1.2E-48 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Pfam PF00108 Thiolase, N-terminal domain 13 266 2.2E-55 T 09-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 PIRSF PIRSF000429 8 400 8.4E-121 T 09-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 UA74_RS23835 89e0dfb0ae25a8cde49ad02a9f6e3054 406 SUPERFAMILY SSF53901 277 397 4.45E-39 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 351 2.4E-86 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 354 49.04 T 09-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 Pfam PF00155 Aminotransferase class I and II 25 348 6.7E-50 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 SUPERFAMILY SSF53383 18 349 7.7E-75 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 Gene3D G3DSA:3.90.1150.10 250 353 1.6E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 09-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 Gene3D G3DSA:3.40.640.10 49 249 1.7E-54 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS00780 94c1eb168803467ee7a6030eb029a3d1 355 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 355 45.82 T 09-03-2017 IPR024892 Putative phenylalanine aminotransferase UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 Gene3D G3DSA:1.10.630.10 8 404 1.1E-121 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 343 352 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 146 162 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 294 321 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 163 178 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 277 288 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 99 110 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 322 337 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 200 222 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 352 363 4.4E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 Pfam PF00067 Cytochrome P450 224 373 2.7E-21 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 SUPERFAMILY SSF48264 16 403 1.7E-93 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 343 352 1.1E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 352 363 1.1E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 277 288 1.1E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS30210 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 242 259 1.1E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:1.25.40.10 870 967 3.6E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Pfam PF00931 NB-ARC domain 307 550 4.8E-11 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:1.25.40.10 721 869 7.7E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:1.25.40.10 107 218 7.7E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:3.40.50.300 432 483 0.001 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:3.40.50.300 299 334 0.001 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 PRINTS PR00364 Disease resistance protein signature 389 403 1.5E-9 T 09-03-2017 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 PRINTS PR00364 Disease resistance protein signature 311 326 1.5E-9 T 09-03-2017 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 PRINTS PR00364 Disease resistance protein signature 476 490 1.5E-9 T 09-03-2017 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Pfam PF03704 Bacterial transcriptional activator domain 97 240 7.6E-26 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF48452 851 966 1.14E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF48452 93 256 1.24E-29 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF46894 2 81 2.21E-5 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF48452 727 874 2.09E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 Pfam PF13424 Tetratricopeptide repeat 856 924 6.1E-9 T 09-03-2017 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 935 968 170.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 772 805 420.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 812 845 260.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 855 891 460.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 192 225 190.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 732 765 270.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 895 928 0.68 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF52540 280 546 8.26E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06475 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM01043 97 242 2.0E-32 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS17425 745759acdc51e1dc602bc14a085b7b1c 344 Pfam PF00107 Zinc-binding dehydrogenase 178 302 1.7E-18 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS17425 745759acdc51e1dc602bc14a085b7b1c 344 SUPERFAMILY SSF50129 1 168 9.59E-44 T 09-03-2017 IPR011032 GroES-like UA74_RS17425 745759acdc51e1dc602bc14a085b7b1c 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 7.5E-23 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS17425 745759acdc51e1dc602bc14a085b7b1c 344 Gene3D G3DSA:3.90.180.10 1 169 9.8E-34 T 09-03-2017 IPR011032 GroES-like UA74_RS17425 745759acdc51e1dc602bc14a085b7b1c 344 SUPERFAMILY SSF51735 148 310 1.41E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17425 745759acdc51e1dc602bc14a085b7b1c 344 Gene3D G3DSA:3.40.50.720 170 289 3.2E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00140 8616244d962c0875a9bc677dd80d5bc1 478 SMART SM00332 2 233 1.6E-24 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS00140 8616244d962c0875a9bc677dd80d5bc1 478 Pfam PF13672 Protein phosphatase 2C 18 199 1.4E-11 T 09-03-2017 UA74_RS00140 8616244d962c0875a9bc677dd80d5bc1 478 SMART SM00331 11 235 3.0E-38 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS00140 8616244d962c0875a9bc677dd80d5bc1 478 Gene3D G3DSA:3.60.40.10 3 235 6.6E-66 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS00140 8616244d962c0875a9bc677dd80d5bc1 478 SUPERFAMILY SSF81606 4 234 3.01E-62 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS00125 2edbf5ca4038d692b793002519a509ff 494 SUPERFAMILY SSF56112 9 293 4.79E-73 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS00125 2edbf5ca4038d692b793002519a509ff 494 Gene3D G3DSA:3.30.200.20 4 98 1.0E-25 T 09-03-2017 UA74_RS00125 2edbf5ca4038d692b793002519a509ff 494 Gene3D G3DSA:1.10.510.10 104 262 5.5E-42 T 09-03-2017 UA74_RS00125 2edbf5ca4038d692b793002519a509ff 494 SMART SM00220 12 273 1.3E-55 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS00125 2edbf5ca4038d692b793002519a509ff 494 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS00125 2edbf5ca4038d692b793002519a509ff 494 Pfam PF00069 Protein kinase domain 13 262 3.9E-43 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS02470 7a0aada0b17f5a41c34ed634cdaf0113 282 Gene3D G3DSA:1.10.12.10 220 270 3.1E-26 T 09-03-2017 IPR014748 Crontonase, C-terminal UA74_RS02470 7a0aada0b17f5a41c34ed634cdaf0113 282 Gene3D G3DSA:3.90.226.10 11 218 2.2E-68 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS02470 7a0aada0b17f5a41c34ed634cdaf0113 282 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 276 1.7E-76 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 UA74_RS02470 7a0aada0b17f5a41c34ed634cdaf0113 282 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 7 281 53.656 T 09-03-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 UA74_RS02470 7a0aada0b17f5a41c34ed634cdaf0113 282 TIGRFAM TIGR01929 menB: naphthoate synthase 13 278 1.1E-128 T 09-03-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 UA74_RS02470 7a0aada0b17f5a41c34ed634cdaf0113 282 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 120 140 - T 09-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 UA74_RS02470 7a0aada0b17f5a41c34ed634cdaf0113 282 SUPERFAMILY SSF52096 10 278 1.17E-76 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 PIRSF PIRSF037226 5 399 9.4E-134 T 09-03-2017 IPR017144 Peptidase M20A, amidohydrolase, predicted UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 Gene3D G3DSA:3.30.70.360 171 275 1.9E-21 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 SUPERFAMILY SSF55031 172 275 1.11E-18 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 Pfam PF07687 Peptidase dimerisation domain 169 266 8.4E-9 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 Gene3D G3DSA:3.40.630.10 282 386 9.9E-63 T 09-03-2017 UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 Gene3D G3DSA:3.40.630.10 10 170 9.9E-63 T 09-03-2017 UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 SUPERFAMILY SSF53187 17 185 2.77E-58 T 09-03-2017 UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 SUPERFAMILY SSF53187 285 381 2.77E-58 T 09-03-2017 UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 352 2.5E-57 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 UA74_RS27225 91e36d072ebbecd48dff4a3478e60ddf 408 Pfam PF01546 Peptidase family M20/M25/M40 94 348 3.6E-7 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS30160 494675e7cad95f195d5fea125d3f6198 256 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 162 169 - T 09-03-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 UA74_RS30160 494675e7cad95f195d5fea125d3f6198 256 Gene3D G3DSA:3.20.20.150 1 252 3.4E-55 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS30160 494675e7cad95f195d5fea125d3f6198 256 SUPERFAMILY SSF51658 1 243 3.01E-51 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS30160 494675e7cad95f195d5fea125d3f6198 256 Pfam PF01261 Xylose isomerase-like TIM barrel 16 218 7.1E-22 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS30160 494675e7cad95f195d5fea125d3f6198 256 SMART SM00518 2 254 1.8E-44 T 09-03-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 SUPERFAMILY SSF55920 9 259 9.29E-75 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 Hamap MF_01974 Methionine aminopeptidase [map]. 8 261 37.711 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 Pfam PF00557 Metallopeptidase family M24 17 252 5.2E-43 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 8 260 1.0E-82 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 Gene3D G3DSA:3.90.230.10 9 261 1.4E-80 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 172 184 1.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 203 215 1.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 96 112 1.1E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS03095 1f12e0c4bb74c41ddc3cec376f6d9447 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 178 196 - T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS02675 a79716351ea12789b1104ca3d552fe69 397 Pfam PF02687 FtsX-like permease family 280 391 6.1E-22 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS02675 a79716351ea12789b1104ca3d552fe69 397 Pfam PF12704 MacB-like periplasmic core domain 31 194 1.5E-17 T 09-03-2017 IPR025857 MacB-like periplasmic core domain UA74_RS19870 65f5f66377f57c2f3ea8cc53a7af1186 453 SUPERFAMILY SSF103473 11 406 1.83E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19870 65f5f66377f57c2f3ea8cc53a7af1186 453 Pfam PF07690 Major Facilitator Superfamily 221 402 2.4E-12 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS19870 65f5f66377f57c2f3ea8cc53a7af1186 453 Pfam PF07690 Major Facilitator Superfamily 13 193 1.6E-13 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS19870 65f5f66377f57c2f3ea8cc53a7af1186 453 Gene3D G3DSA:1.20.1250.20 213 405 3.4E-15 T 09-03-2017 UA74_RS19870 65f5f66377f57c2f3ea8cc53a7af1186 453 Gene3D G3DSA:1.20.1250.20 11 190 2.6E-16 T 09-03-2017 UA74_RS23280 3eff044b5a058bdc73084c7790fa041c 255 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 223 9.3E-47 T 09-03-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_RS23280 3eff044b5a058bdc73084c7790fa041c 255 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 42 7.9E-11 T 09-03-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_RS23280 3eff044b5a058bdc73084c7790fa041c 255 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 225 9.5E-55 T 09-03-2017 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 UA74_RS22850 dcd319e9dd06d6fac4b8f3530fb81580 439 Gene3D G3DSA:1.20.1250.20 9 189 2.4E-22 T 09-03-2017 UA74_RS22850 dcd319e9dd06d6fac4b8f3530fb81580 439 Gene3D G3DSA:1.20.1250.20 215 382 3.1E-9 T 09-03-2017 UA74_RS22850 dcd319e9dd06d6fac4b8f3530fb81580 439 SUPERFAMILY SSF103473 8 387 2.35E-49 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22850 dcd319e9dd06d6fac4b8f3530fb81580 439 Pfam PF07690 Major Facilitator Superfamily 13 353 1.8E-29 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 SMART SM00421 153 210 1.6E-21 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 SMART SM00448 6 118 5.3E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 2.8E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 2.8E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 2.8E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 SUPERFAMILY SSF52172 6 123 6.97E-29 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 Gene3D G3DSA:1.10.10.10 121 215 2.2E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 SUPERFAMILY SSF46894 148 215 5.78E-21 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 Gene3D G3DSA:3.40.50.2300 3 120 1.0E-30 T 09-03-2017 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 Pfam PF00072 Response regulator receiver domain 8 119 4.8E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 2.6E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS30285 3c700907305bc63e1d59e3f4c787f031 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS01005 f0d86b2d15310d6bccb73e1d57e243d6 127 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 21.244 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS01005 f0d86b2d15310d6bccb73e1d57e243d6 127 Pfam PF02575 YbaB/EbfC DNA-binding family 13 101 1.3E-33 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS01005 f0d86b2d15310d6bccb73e1d57e243d6 127 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 7 94 1.2E-24 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS01005 f0d86b2d15310d6bccb73e1d57e243d6 127 SUPERFAMILY SSF82607 8 100 3.14E-28 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS01005 f0d86b2d15310d6bccb73e1d57e243d6 127 Gene3D G3DSA:3.30.1310.10 4 106 3.9E-40 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS05925 90d933742fb674263563f1ee82f6e0d7 209 SUPERFAMILY SSF46689 12 84 2.0E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05925 90d933742fb674263563f1ee82f6e0d7 209 Gene3D G3DSA:1.10.10.60 11 64 1.6E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05925 90d933742fb674263563f1ee82f6e0d7 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 64 2.0E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05925 90d933742fb674263563f1ee82f6e0d7 209 Gene3D G3DSA:1.10.357.10 65 205 8.8E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 Pfam PF00551 Formyl transferase 7 178 1.3E-29 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 SUPERFAMILY SSF53328 1 206 2.35E-53 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 Gene3D G3DSA:3.40.50.170 1 206 9.1E-55 T 09-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 SUPERFAMILY SSF50486 205 308 7.85E-23 T 09-03-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 30.472 T 09-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 Gene3D G3DSA:3.10.25.10 208 308 1.4E-24 T 09-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 304 7.1E-63 T 09-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 UA74_RS12365 407bc7f38af3e48ecea15be8227c327c 309 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 1.7E-17 T 09-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_RS17525 9558833ad07d9adde54e6c9a30aea643 453 Gene3D G3DSA:3.90.1150.10 15 73 2.0E-31 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS17525 9558833ad07d9adde54e6c9a30aea643 453 Gene3D G3DSA:3.90.1150.10 349 449 2.0E-31 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS17525 9558833ad07d9adde54e6c9a30aea643 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS17525 9558833ad07d9adde54e6c9a30aea643 453 Gene3D G3DSA:3.40.640.10 75 347 9.7E-76 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS17525 9558833ad07d9adde54e6c9a30aea643 453 SUPERFAMILY SSF53383 29 448 9.15E-108 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS17525 9558833ad07d9adde54e6c9a30aea643 453 Pfam PF00202 Aminotransferase class-III 37 448 2.6E-89 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 Gene3D G3DSA:1.10.10.10 148 214 4.0E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 SUPERFAMILY SSF52172 2 134 2.99E-16 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 196 1.7E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 SUPERFAMILY SSF46894 133 200 8.84E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 Gene3D G3DSA:3.40.50.2300 2 147 1.7E-23 T 09-03-2017 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 SMART SM00448 1 120 8.9E-8 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 SMART SM00421 148 211 1.6E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 Pfam PF00072 Response regulator receiver domain 3 113 2.5E-14 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.3E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.3E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21490 4fc5455a10ada86d9f05e7e0382564c0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.3E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS19660 ca7866de7aee69ad391a0fe962d5280a 344 SUPERFAMILY SSF53613 15 315 2.03E-63 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS19660 ca7866de7aee69ad391a0fe962d5280a 344 Pfam PF00294 pfkB family carbohydrate kinase 16 311 6.6E-44 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS19660 ca7866de7aee69ad391a0fe962d5280a 344 Gene3D G3DSA:3.40.1190.20 12 321 1.8E-67 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS19660 ca7866de7aee69ad391a0fe962d5280a 344 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 264 277 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS18980 0f6a28f0b834f5f2ea8303061e09ce73 223 SUPERFAMILY SSF46785 4 150 2.68E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18980 0f6a28f0b834f5f2ea8303061e09ce73 223 Pfam PF12802 MarR family 37 98 2.1E-11 T 09-03-2017 UA74_RS18980 0f6a28f0b834f5f2ea8303061e09ce73 223 Gene3D G3DSA:1.10.10.10 3 151 7.7E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18980 0f6a28f0b834f5f2ea8303061e09ce73 223 SMART SM00347 32 134 9.6E-15 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS01245 3998517bfaec1edeac5ab013664fb136 249 Gene3D G3DSA:3.90.79.10 50 215 3.0E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS01245 3998517bfaec1edeac5ab013664fb136 249 Pfam PF00293 NUDIX domain 54 174 1.4E-11 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS01245 3998517bfaec1edeac5ab013664fb136 249 SUPERFAMILY SSF55811 55 209 3.25E-23 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS28480 3f061aff0b63406b67d52d8ac2cb757e 498 SUPERFAMILY SSF55931 40 154 3.04E-50 T 09-03-2017 UA74_RS28480 3f061aff0b63406b67d52d8ac2cb757e 498 SUPERFAMILY SSF55931 184 463 3.04E-50 T 09-03-2017 UA74_RS28480 3f061aff0b63406b67d52d8ac2cb757e 498 PIRSF PIRSF012666 1 498 6.0E-211 T 09-03-2017 IPR016602 Uncharacterised conserved protein UCP012666 UA74_RS29430 385752cafeace2f53d6f2c2897579c42 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 38.865 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29430 385752cafeace2f53d6f2c2897579c42 223 Gene3D G3DSA:3.40.50.880 1 220 3.0E-38 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS29430 385752cafeace2f53d6f2c2897579c42 223 PIRSF PIRSF001586 1 223 4.4E-76 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29430 385752cafeace2f53d6f2c2897579c42 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 4.1E-79 T 09-03-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29430 385752cafeace2f53d6f2c2897579c42 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 203 1.1E-32 T 09-03-2017 UA74_RS29430 385752cafeace2f53d6f2c2897579c42 223 SUPERFAMILY SSF52317 1 218 2.87E-67 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS29430 385752cafeace2f53d6f2c2897579c42 223 SMART SM01211 1 220 2.8E-119 T 09-03-2017 UA74_RS04775 4c1f0b8d6bfdb6461919aa12d01448ae 357 SUPERFAMILY SSF55486 227 334 3.67E-11 T 09-03-2017 UA74_RS04775 4c1f0b8d6bfdb6461919aa12d01448ae 357 Pfam PF11350 Protein of unknown function (DUF3152) 148 357 2.9E-63 T 09-03-2017 IPR022603 Domain of unknown function DUF3152 UA74_RS03055 2dc3c3885f0b1089da06bfdb5d6648f5 267 Gene3D G3DSA:1.10.260.40 1 51 8.4E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS03055 2dc3c3885f0b1089da06bfdb5d6648f5 267 SMART SM00530 1 52 9.0E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS03055 2dc3c3885f0b1089da06bfdb5d6648f5 267 Pfam PF13560 Helix-turn-helix domain 1 55 1.7E-12 T 09-03-2017 UA74_RS03055 2dc3c3885f0b1089da06bfdb5d6648f5 267 SUPERFAMILY SSF47413 1 51 2.17E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS06310 d56de3b0464cc99325938d996c4dc481 92 Pfam PF02597 ThiS family 5 90 3.9E-19 T 09-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 UA74_RS06310 d56de3b0464cc99325938d996c4dc481 92 SUPERFAMILY SSF54285 1 90 1.6E-23 T 09-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UA74_RS06310 d56de3b0464cc99325938d996c4dc481 92 Gene3D G3DSA:3.10.20.30 3 88 1.0E-28 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS13490 0c3d6722effe883f210c3b332f733784 213 SUPERFAMILY SSF53335 9 183 1.38E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13490 0c3d6722effe883f210c3b332f733784 213 Gene3D G3DSA:3.40.50.150 25 206 1.2E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13490 0c3d6722effe883f210c3b332f733784 213 Pfam PF13649 Methyltransferase domain 44 135 2.5E-16 T 09-03-2017 UA74_RS04415 4ccc88f195a47199f606dcb4fd8c0f7d 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 305 4.7E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04415 4ccc88f195a47199f606dcb4fd8c0f7d 309 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 70 2.1E-14 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_RS04415 4ccc88f195a47199f606dcb4fd8c0f7d 309 SUPERFAMILY SSF161098 100 286 8.5E-28 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04415 4ccc88f195a47199f606dcb4fd8c0f7d 309 Gene3D G3DSA:1.10.3720.10 95 302 5.2E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS15125 1d42afd2110993bc5ac2102afb3c6b70 294 SUPERFAMILY SSF51735 4 247 2.78E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15125 1d42afd2110993bc5ac2102afb3c6b70 294 Pfam PF13460 NAD(P)H-binding 8 187 3.0E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15125 1d42afd2110993bc5ac2102afb3c6b70 294 Gene3D G3DSA:3.40.50.720 1 219 3.8E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18650 b4275537038bb137f0c4bdfd4370b30e 422 SUPERFAMILY SSF88946 6 77 2.79E-11 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18650 b4275537038bb137f0c4bdfd4370b30e 422 Gene3D G3DSA:1.10.10.10 114 171 2.2E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18650 b4275537038bb137f0c4bdfd4370b30e 422 Gene3D G3DSA:1.10.1740.10 7 95 1.4E-10 T 09-03-2017 UA74_RS18650 b4275537038bb137f0c4bdfd4370b30e 422 Pfam PF04542 Sigma-70 region 2 14 80 4.8E-7 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18650 b4275537038bb137f0c4bdfd4370b30e 422 Pfam PF08281 Sigma-70, region 4 119 169 1.2E-8 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18650 b4275537038bb137f0c4bdfd4370b30e 422 SUPERFAMILY SSF88659 114 171 3.05E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS11760 829d18ac110da251db2b35d0146b5414 866 Gene3D G3DSA:1.10.510.10 464 604 2.2E-32 T 09-03-2017 UA74_RS11760 829d18ac110da251db2b35d0146b5414 866 Gene3D G3DSA:3.30.200.20 382 463 7.6E-24 T 09-03-2017 UA74_RS11760 829d18ac110da251db2b35d0146b5414 866 Pfam PF00069 Protein kinase domain 389 609 5.1E-43 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS11760 829d18ac110da251db2b35d0146b5414 866 SUPERFAMILY SSF56112 386 639 6.47E-60 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS11760 829d18ac110da251db2b35d0146b5414 866 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 394 417 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS11760 829d18ac110da251db2b35d0146b5414 866 SMART SM00220 388 645 1.0E-46 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS11760 829d18ac110da251db2b35d0146b5414 866 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 508 520 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS07265 ca167f3fc1f931154ea77e516350ee70 487 Gene3D G3DSA:3.40.309.10 248 429 9.2E-46 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS07265 ca167f3fc1f931154ea77e516350ee70 487 Gene3D G3DSA:3.40.605.10 3 247 2.8E-64 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS07265 ca167f3fc1f931154ea77e516350ee70 487 SUPERFAMILY SSF53720 4 455 2.75E-113 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS07265 ca167f3fc1f931154ea77e516350ee70 487 Pfam PF00171 Aldehyde dehydrogenase family 4 453 1.1E-110 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS07265 ca167f3fc1f931154ea77e516350ee70 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 232 239 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS05350 8b63d5ce8c9d6abb142819ec01dfc9a1 144 Pfam PF01638 HxlR-like helix-turn-helix 34 119 4.2E-31 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS05350 8b63d5ce8c9d6abb142819ec01dfc9a1 144 SUPERFAMILY SSF46785 20 132 2.22E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05350 8b63d5ce8c9d6abb142819ec01dfc9a1 144 Gene3D G3DSA:1.10.10.10 10 131 5.8E-49 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 09-03-2017 IPR020583 Inositol monophosphatase, metal-binding site UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 Gene3D G3DSA:3.30.540.10 5 154 1.0E-44 T 09-03-2017 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 3.2E-20 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 3.2E-20 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 3.2E-20 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 3.2E-20 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 Pfam PF00459 Inositol monophosphatase family 9 235 8.5E-46 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 Gene3D G3DSA:3.40.190.80 155 260 1.3E-19 T 09-03-2017 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 09-03-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 7 258 1.8E-84 T 09-03-2017 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 UA74_RS27025 386991074e8d9c44e0457c58c25c8fe4 261 SUPERFAMILY SSF56655 6 259 5.76E-71 T 09-03-2017 UA74_RS05625 8aaa00e6a4ad57108317733c6632557d 336 SUPERFAMILY SSF53850 47 283 3.8E-10 T 09-03-2017 UA74_RS05625 8aaa00e6a4ad57108317733c6632557d 336 PIRSF PIRSF017082 4 331 1.0E-68 T 09-03-2017 IPR005064 Bordetella uptake gene GO:0030288 UA74_RS05625 8aaa00e6a4ad57108317733c6632557d 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 327 3.9E-44 T 09-03-2017 IPR005064 Bordetella uptake gene GO:0030288 UA74_RS27725 6b85475bbcd60cd16a0d14333d087697 265 Gene3D G3DSA:3.60.10.10 2 264 5.8E-87 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS27725 6b85475bbcd60cd16a0d14333d087697 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 2.0E-25 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS27725 6b85475bbcd60cd16a0d14333d087697 265 SUPERFAMILY SSF56219 2 264 2.36E-72 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS27725 6b85475bbcd60cd16a0d14333d087697 265 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 264 3.0E-73 T 09-03-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 UA74_RS27725 6b85475bbcd60cd16a0d14333d087697 265 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 5 263 1.9E-71 T 09-03-2017 UA74_RS26840 ebfa4f5f4fb641d971bd8a9bfbf04780 303 Pfam PF00535 Glycosyl transferase family 2 24 204 1.7E-15 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS26840 ebfa4f5f4fb641d971bd8a9bfbf04780 303 SUPERFAMILY SSF53448 22 269 1.38E-39 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS26840 ebfa4f5f4fb641d971bd8a9bfbf04780 303 Gene3D G3DSA:3.90.550.10 23 264 2.6E-32 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS29210 43dba1ee14b6872d6d31e67ae3c61253 287 Pfam PF00561 alpha/beta hydrolase fold 20 269 1.6E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS29210 43dba1ee14b6872d6d31e67ae3c61253 287 Gene3D G3DSA:3.40.50.1820 4 269 8.2E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS29210 43dba1ee14b6872d6d31e67ae3c61253 287 SUPERFAMILY SSF53474 3 271 1.46E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08355 5253a72cc803d48347d64d9411dafd59 143 SUPERFAMILY SSF81301 7 117 2.29E-38 T 09-03-2017 UA74_RS08355 5253a72cc803d48347d64d9411dafd59 143 Pfam PF02410 Ribosomal silencing factor during starvation 15 108 2.0E-23 T 09-03-2017 UA74_RS08355 5253a72cc803d48347d64d9411dafd59 143 Gene3D G3DSA:3.30.460.10 7 112 8.3E-35 T 09-03-2017 UA74_RS08355 5253a72cc803d48347d64d9411dafd59 143 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 14 108 1.3E-31 T 09-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS UA74_RS08355 5253a72cc803d48347d64d9411dafd59 143 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 23.214 T 09-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 SMART SM01390 3 90 1.4E-44 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 7.0E-79 T 09-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 SMART SM00363 91 156 4.8E-16 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 SUPERFAMILY SSF55174 3 201 3.66E-65 T 09-03-2017 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 Gene3D G3DSA:3.10.290.10 94 193 3.1E-27 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 1.5E-28 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 Pfam PF01479 S4 domain 92 138 1.2E-19 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.752 T 09-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 Gene3D G3DSA:1.10.1050.10 1 93 9.7E-40 T 09-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 UA74_RS03130 14c0b2c55d4d1a6716bd105531b25784 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 09-03-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 Gene3D G3DSA:1.10.287.80 254 300 2.2E-24 T 09-03-2017 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 305 4.6E-102 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 SUPERFAMILY SSF52943 3 305 2.62E-80 T 09-03-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 Gene3D G3DSA:1.10.287.80 220 253 2.1E-28 T 09-03-2017 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 Gene3D G3DSA:1.10.287.80 20 61 2.1E-28 T 09-03-2017 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 Gene3D G3DSA:3.40.1380.10 64 207 2.0E-43 T 09-03-2017 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 305 35.235 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 Pfam PF00231 ATP synthase 5 305 1.4E-88 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 252 271 1.1E-34 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.1E-34 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 181 198 1.1E-34 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07170 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 283 304 1.1E-34 T 09-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 ProSitePatterns PS00483 Dihydroorotase signature 2. 298 309 - T 09-03-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 SUPERFAMILY SSF51338 13 51 8.06E-13 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 SUPERFAMILY SSF51338 365 421 8.06E-13 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 423 34.043 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 Gene3D G3DSA:3.20.20.140 67 403 2.6E-88 T 09-03-2017 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 420 8.5E-99 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 Gene3D G3DSA:2.30.40.10 17 66 3.3E-12 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 Pfam PF01979 Amidohydrolase family 48 418 1.2E-11 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS24125 1db1959ba74bd90660297fab8f442e46 423 SUPERFAMILY SSF51556 52 362 2.76E-82 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 SUPERFAMILY SSF49503 211 342 2.54E-23 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 Gene3D G3DSA:2.60.40.420 48 210 2.4E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 Pfam PF07731 Multicopper oxidase 408 514 1.9E-20 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 SUPERFAMILY SSF49503 44 199 3.3E-22 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 Gene3D G3DSA:2.60.40.420 388 514 8.3E-32 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 Pfam PF07732 Multicopper oxidase 162 204 3.8E-4 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 Pfam PF07732 Multicopper oxidase 75 137 5.2E-12 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 Gene3D G3DSA:2.60.40.420 211 343 1.2E-31 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11375 1483cfc6abc9e230967f98db0e2a4a67 515 SUPERFAMILY SSF49503 406 514 2.04E-26 T 09-03-2017 IPR008972 Cupredoxin UA74_RS07125 1909027e647a9ab3c0a673ca09ca9434 215 Gene3D G3DSA:3.90.870.10 6 209 1.2E-68 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain UA74_RS07125 1909027e647a9ab3c0a673ca09ca9434 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 11 207 2.2E-62 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 UA74_RS07125 1909027e647a9ab3c0a673ca09ca9434 215 SUPERFAMILY SSF55821 5 206 4.58E-57 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain UA74_RS07125 1909027e647a9ab3c0a673ca09ca9434 215 Pfam PF01300 Telomere recombination 23 197 6.9E-48 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 UA74_RS11680 5793be2831a7e390fe3424b8fbcc8c41 312 Pfam PF12697 Alpha/beta hydrolase family 48 283 2.8E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS11680 5793be2831a7e390fe3424b8fbcc8c41 312 Gene3D G3DSA:3.40.50.1820 14 283 6.1E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS11680 5793be2831a7e390fe3424b8fbcc8c41 312 SUPERFAMILY SSF53474 17 284 2.03E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 Pfam PF00817 impB/mucB/samB family 1 146 7.8E-36 T 09-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 Hamap MF_01113 DNA polymerase IV [dinB]. 1 341 29.986 T 09-03-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 Pfam PF11799 impB/mucB/samB family C-terminal domain 228 338 4.4E-19 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 Pfam PF11798 IMS family HHH motif 160 189 1.9E-5 T 09-03-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 Gene3D G3DSA:3.30.1490.100 234 340 1.9E-26 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 Gene3D G3DSA:1.10.150.20 161 230 1.5E-18 T 09-03-2017 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 SUPERFAMILY SSF100879 232 332 9.26E-23 T 09-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 SUPERFAMILY SSF56672 1 230 4.45E-63 T 09-03-2017 UA74_RS07325 5845387cdce9e7fb236602247b59ae99 513 Gene3D G3DSA:3.30.70.270 57 156 5.5E-22 T 09-03-2017 UA74_RS29250 9bfc62bfee606aa72006b0c80456a053 677 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 522 605 5.3E-15 T 09-03-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_RS29250 9bfc62bfee606aa72006b0c80456a053 677 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 232 396 5.3E-36 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS29250 9bfc62bfee606aa72006b0c80456a053 677 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 231 396 4.6E-44 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS05720 b9b4d636fd0600e1be7038ac9302bf29 488 SUPERFAMILY SSF56112 8 268 4.45E-68 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS05720 b9b4d636fd0600e1be7038ac9302bf29 488 Pfam PF00069 Protein kinase domain 17 268 3.8E-46 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS05720 b9b4d636fd0600e1be7038ac9302bf29 488 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS05720 b9b4d636fd0600e1be7038ac9302bf29 488 SMART SM00220 15 274 1.2E-55 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS05720 b9b4d636fd0600e1be7038ac9302bf29 488 Gene3D G3DSA:1.10.510.10 87 268 1.3E-47 T 09-03-2017 UA74_RS05720 b9b4d636fd0600e1be7038ac9302bf29 488 Gene3D G3DSA:3.30.200.20 7 86 2.6E-21 T 09-03-2017 UA74_RS05720 b9b4d636fd0600e1be7038ac9302bf29 488 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 Gene3D G3DSA:2.40.10.10 58 243 2.4E-34 T 09-03-2017 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 102 116 1.0E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 50 65 1.0E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 188 200 1.0E-12 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 SMART SM00020 21 239 1.3E-38 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 Pfam PF00089 Trypsin 22 239 1.1E-36 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 Gene3D G3DSA:2.40.10.10 22 57 7.7E-14 T 09-03-2017 UA74_RS01455 26c6f4c7bd5d68787e1adbd659c54cf2 245 SUPERFAMILY SSF50494 20 243 4.66E-47 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS07840 45644b72601bf9e93377383a6e22eaa8 250 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 78 1.8E-5 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS07840 45644b72601bf9e93377383a6e22eaa8 250 SUPERFAMILY SSF48452 92 243 6.83E-29 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS07840 45644b72601bf9e93377383a6e22eaa8 250 SMART SM01043 96 240 6.0E-40 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS07840 45644b72601bf9e93377383a6e22eaa8 250 SMART SM00862 16 89 4.7E-6 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS07840 45644b72601bf9e93377383a6e22eaa8 250 Pfam PF03704 Bacterial transcriptional activator domain 97 239 2.3E-39 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS07840 45644b72601bf9e93377383a6e22eaa8 250 SUPERFAMILY SSF46894 2 89 1.47E-12 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS07840 45644b72601bf9e93377383a6e22eaa8 250 Gene3D G3DSA:1.10.10.10 13 88 4.8E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15870 fcb322de7ebedbc2037884c30196c646 303 Gene3D G3DSA:3.90.25.10 181 289 3.8E-14 T 09-03-2017 UA74_RS15870 fcb322de7ebedbc2037884c30196c646 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 218 1.4E-40 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS15870 fcb322de7ebedbc2037884c30196c646 303 Gene3D G3DSA:3.40.50.720 4 180 4.3E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15870 fcb322de7ebedbc2037884c30196c646 303 SUPERFAMILY SSF51735 4 290 3.13E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07020 c691f9c37d2ff03ceaffb4e6bfd210e0 362 SUPERFAMILY SSF51556 58 323 5.3E-36 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS07020 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Pfam PF01979 Amidohydrolase family 54 359 1.5E-11 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS07020 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Gene3D G3DSA:3.20.20.140 59 323 9.1E-38 T 09-03-2017 UA74_RS07020 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Gene3D G3DSA:2.30.40.10 51 58 4.4E-6 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS07020 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Gene3D G3DSA:2.30.40.10 324 360 4.4E-6 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 375 437 1.5E-14 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 579 642 1.4E-5 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 445 507 8.6E-10 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 515 574 4.3E-10 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 SUPERFAMILY SSF56112 8 276 1.31E-76 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:1.10.510.10 80 269 7.1E-53 T 09-03-2017 UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:3.30.200.20 4 79 2.2E-29 T 09-03-2017 UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 371 439 2.2E-13 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 440 509 5.9E-7 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 576 644 0.019 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 510 575 2.5E-12 T 09-03-2017 IPR005543 PASTA domain UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF00069 Protein kinase domain 11 265 6.0E-50 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS00120 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00220 11 274 1.7E-64 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 Pfam PF00196 Bacterial regulatory proteins, luxR family 864 916 3.5E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 ProSitePatterns PS00622 LuxR-type HTH domain signature. 880 907 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 Gene3D G3DSA:1.25.40.10 610 764 2.7E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 SUPERFAMILY SSF46894 855 917 1.56E-16 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 Pfam PF13191 AAA ATPase domain 11 174 5.9E-15 T 09-03-2017 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 Gene3D G3DSA:1.10.10.10 861 916 5.1E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 866 880 5.6E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 896 908 5.6E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 880 896 5.6E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17340 5e49523b73367c82e14c7b9c78e64476 922 SMART SM00421 863 920 6.6E-22 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21885 157763d98a36d1a054ac81838cf27e88 294 SUPERFAMILY SSF53474 21 258 3.48E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21885 157763d98a36d1a054ac81838cf27e88 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 2.5E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS21885 157763d98a36d1a054ac81838cf27e88 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 2.5E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS21885 157763d98a36d1a054ac81838cf27e88 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.5E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS21885 157763d98a36d1a054ac81838cf27e88 294 Gene3D G3DSA:3.40.50.1820 23 258 5.3E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21885 157763d98a36d1a054ac81838cf27e88 294 Pfam PF00561 alpha/beta hydrolase fold 26 150 3.7E-20 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS24940 837771a49449dd449373a1d7cac5c253 140 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 10 118 7.0E-33 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_RS24940 837771a49449dd449373a1d7cac5c253 140 SUPERFAMILY SSF52980 6 129 8.58E-33 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS24940 837771a49449dd449373a1d7cac5c253 140 Gene3D G3DSA:3.40.960.10 19 133 2.2E-37 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_RS24940 837771a49449dd449373a1d7cac5c253 140 Pfam PF03852 DNA mismatch endonuclease Vsr 9 71 3.2E-16 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 Pfam PF00486 Transcriptional regulatory protein, C terminal 18 73 1.2E-6 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 Pfam PF03704 Bacterial transcriptional activator domain 104 249 6.4E-34 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 SMART SM00862 11 97 1.3E-5 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 Gene3D G3DSA:1.10.10.10 19 77 1.6E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 SMART SM01043 104 249 3.3E-30 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 SUPERFAMILY SSF48452 101 262 7.6E-30 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 Gene3D G3DSA:1.25.40.10 111 228 5.9E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS19415 934275c8cd3f71445794fbbc1f355f8e 287 SUPERFAMILY SSF46894 2 75 5.95E-11 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 283 657 4.6E-51 T 09-03-2017 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 Pfam PF00270 DEAD/DEAH box helicase 276 466 9.2E-6 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 SUPERFAMILY SSF52540 378 465 2.83E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 SUPERFAMILY SSF52540 276 332 2.83E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 SUPERFAMILY SSF52540 513 657 2.83E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 Pfam PF00271 Helicase conserved C-terminal domain 545 656 3.4E-5 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 19 203 7.4E-21 T 09-03-2017 IPR006483 CRISPR-associated Cas3-HD domain UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 SMART SM00487 259 496 0.0017 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 Gene3D G3DSA:3.40.50.300 258 469 2.6E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17770 9611bc0b1134f7a3a5d241049314a142 913 Gene3D G3DSA:3.40.50.300 543 655 6.9E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27890 b33fb527efce506bce1d02c7f6648165 481 Pfam PF07690 Major Facilitator Superfamily 13 393 6.5E-22 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS27890 b33fb527efce506bce1d02c7f6648165 481 SUPERFAMILY SSF103473 10 202 4.58E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS27890 b33fb527efce506bce1d02c7f6648165 481 SUPERFAMILY SSF103473 239 434 4.58E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS27890 b33fb527efce506bce1d02c7f6648165 481 Gene3D G3DSA:1.20.1250.20 255 434 3.7E-15 T 09-03-2017 UA74_RS27890 b33fb527efce506bce1d02c7f6648165 481 Gene3D G3DSA:1.20.1250.20 9 194 1.9E-18 T 09-03-2017 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 Gene3D G3DSA:3.40.50.300 2 178 2.0E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 4 17 3.9E-31 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 32 46 3.9E-31 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 81 97 3.9E-31 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 130 145 3.9E-31 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 147 161 3.9E-31 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 Pfam PF00406 Adenylate kinase 5 159 7.9E-51 T 09-03-2017 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 Hamap MF_00235 Adenylate kinase [adk]. 1 181 41.574 T 09-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 09-03-2017 UA74_RS03090 c48c43a48948ffd20b161ed194e3a27c 186 SUPERFAMILY SSF52540 2 180 1.78E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 4.0E-56 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 1.2E-20 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 4.0E-33 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 4.0E-33 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.0E-33 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 4.0E-33 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 4.0E-33 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 9.4E-49 T 09-03-2017 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 SUPERFAMILY SSF51905 3 94 6.63E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 SUPERFAMILY SSF51905 129 337 6.63E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Gene3D G3DSA:3.30.390.30 343 460 4.5E-28 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Gene3D G3DSA:3.50.50.60 3 145 7.9E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 SUPERFAMILY SSF55424 347 461 1.07E-25 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Gene3D G3DSA:3.50.50.60 146 337 3.6E-49 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27190 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PIRSF PIRSF000350 1 457 3.8E-81 T 09-03-2017 UA74_RS05540 0b8d50e44c890e041277fcc123131a77 311 Pfam PF03466 LysR substrate binding domain 88 293 7.5E-38 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS05540 0b8d50e44c890e041277fcc123131a77 311 Gene3D G3DSA:3.40.190.10 91 184 2.4E-18 T 09-03-2017 UA74_RS05540 0b8d50e44c890e041277fcc123131a77 311 SUPERFAMILY SSF53850 89 293 4.04E-33 T 09-03-2017 UA74_RS05540 0b8d50e44c890e041277fcc123131a77 311 SUPERFAMILY SSF46785 6 109 1.1E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05540 0b8d50e44c890e041277fcc123131a77 311 Gene3D G3DSA:1.10.10.10 7 88 2.1E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05540 0b8d50e44c890e041277fcc123131a77 311 Gene3D G3DSA:3.40.190.10 185 264 9.9E-20 T 09-03-2017 UA74_RS05540 0b8d50e44c890e041277fcc123131a77 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 5.4E-14 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS17515 d890b0997b4614626e719813be2bab17 387 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 374 7.6E-90 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_RS17515 d890b0997b4614626e719813be2bab17 387 Gene3D G3DSA:3.40.640.10 4 257 2.5E-65 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS17515 d890b0997b4614626e719813be2bab17 387 PIRSF PIRSF000390 1 380 1.3E-88 T 09-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_RS17515 d890b0997b4614626e719813be2bab17 387 Gene3D G3DSA:3.90.1150.10 259 379 2.7E-28 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS17515 d890b0997b4614626e719813be2bab17 387 SUPERFAMILY SSF53383 5 376 6.78E-85 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS04860 1e07977febb37b2a65290172b358f720 290 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 46 117 6.1E-7 T 09-03-2017 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 UA74_RS04860 1e07977febb37b2a65290172b358f720 290 ProSitePatterns PS00893 Nudix box signature. 186 207 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS04860 1e07977febb37b2a65290172b358f720 290 Pfam PF00293 NUDIX domain 154 263 5.8E-19 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS04860 1e07977febb37b2a65290172b358f720 290 Gene3D G3DSA:3.90.79.10 115 289 4.0E-46 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS04860 1e07977febb37b2a65290172b358f720 290 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 121 150 5.0E-10 T 09-03-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 UA74_RS04860 1e07977febb37b2a65290172b358f720 290 SUPERFAMILY SSF55811 104 283 1.02E-45 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 SUPERFAMILY SSF52540 51 309 2.78E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 SUPERFAMILY SSF48452 494 684 1.14E-14 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 Pfam PF13424 Tetratricopeptide repeat 534 601 9.2E-8 T 09-03-2017 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 575 608 110.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 655 688 0.89 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 615 648 400.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 533 566 6.6 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 493 526 39.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 Gene3D G3DSA:1.25.40.10 592 702 5.7E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 PRINTS PR00364 Disease resistance protein signature 157 171 3.1E-8 T 09-03-2017 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 PRINTS PR00364 Disease resistance protein signature 244 258 3.1E-8 T 09-03-2017 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 PRINTS PR00364 Disease resistance protein signature 80 95 3.1E-8 T 09-03-2017 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 Pfam PF00931 NB-ARC domain 71 310 2.7E-13 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 Gene3D G3DSA:1.25.40.10 462 591 9.7E-14 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23150 39334908a40ecd4d19700e6171bc291a 729 Gene3D G3DSA:3.40.50.300 64 131 7.1E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08285 6341da0a8ef8575a69de64ce1c42a21a 222 SUPERFAMILY SSF52540 63 196 5.96E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08285 6341da0a8ef8575a69de64ce1c42a21a 222 Gene3D G3DSA:3.40.50.300 50 162 1.7E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15880 1e2c075dc63dcbd8f45a454ed102a019 514 Pfam PF00501 AMP-binding enzyme 12 393 6.3E-55 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS15880 1e2c075dc63dcbd8f45a454ed102a019 514 Gene3D G3DSA:3.40.50.980 165 320 3.2E-24 T 09-03-2017 UA74_RS15880 1e2c075dc63dcbd8f45a454ed102a019 514 SUPERFAMILY SSF56801 5 502 2.88E-70 T 09-03-2017 UA74_RS15880 1e2c075dc63dcbd8f45a454ed102a019 514 Gene3D G3DSA:3.40.50.980 5 164 8.9E-16 T 09-03-2017 UA74_RS15880 1e2c075dc63dcbd8f45a454ed102a019 514 Gene3D G3DSA:3.30.300.30 394 497 1.9E-4 T 09-03-2017 UA74_RS15880 1e2c075dc63dcbd8f45a454ed102a019 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS15880 1e2c075dc63dcbd8f45a454ed102a019 514 Gene3D G3DSA:2.30.38.10 334 386 5.8E-10 T 09-03-2017 UA74_RS01760 b57ed3f98142b0e3a894fb04e5e1b4d6 417 Gene3D G3DSA:3.40.190.10 41 158 1.4E-7 T 09-03-2017 UA74_RS01760 b57ed3f98142b0e3a894fb04e5e1b4d6 417 Gene3D G3DSA:3.40.190.10 159 348 8.5E-42 T 09-03-2017 UA74_RS01760 b57ed3f98142b0e3a894fb04e5e1b4d6 417 Pfam PF13416 Bacterial extracellular solute-binding protein 53 354 2.5E-42 T 09-03-2017 UA74_RS01760 b57ed3f98142b0e3a894fb04e5e1b4d6 417 SUPERFAMILY SSF53850 36 403 3.47E-79 T 09-03-2017 UA74_RS07005 2aa1705e0b0a3026481f4acccc4e2b53 280 Gene3D G3DSA:3.10.310.10 4 116 1.0E-34 T 09-03-2017 UA74_RS07005 2aa1705e0b0a3026481f4acccc4e2b53 280 PIRSF PIRSF016184 1 280 1.4E-58 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_RS07005 2aa1705e0b0a3026481f4acccc4e2b53 280 SUPERFAMILY SSF54506 1 278 1.92E-60 T 09-03-2017 UA74_RS07005 2aa1705e0b0a3026481f4acccc4e2b53 280 Gene3D G3DSA:3.10.310.10 120 267 3.2E-39 T 09-03-2017 UA74_RS07005 2aa1705e0b0a3026481f4acccc4e2b53 280 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 278 1.5E-49 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_RS07005 2aa1705e0b0a3026481f4acccc4e2b53 280 Pfam PF02567 Phenazine biosynthesis-like protein 10 278 2.3E-70 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_RS21970 eb4963adc3d1c6db85a63ff5d08fe0a4 178 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 21 173 4.0E-31 T 09-03-2017 IPR017516 AbrB duplication UA74_RS21970 eb4963adc3d1c6db85a63ff5d08fe0a4 178 Pfam PF05145 Putative ammonia monooxygenase 19 174 1.4E-28 T 09-03-2017 IPR007820 AbrB family GO:0010468|GO:0016021 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 453 1.3E-64 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 09-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 SUPERFAMILY SSF53067 3 257 6.05E-88 T 09-03-2017 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 Hamap MF_00186 Glycerol kinase [glpK]. 2 500 55.554 T 09-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 Gene3D G3DSA:3.30.420.40 257 501 6.3E-102 T 09-03-2017 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 SUPERFAMILY SSF53067 257 500 4.07E-83 T 09-03-2017 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 254 7.0E-74 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 PIRSF PIRSF000538 2 504 1.7E-168 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 499 1.2E-224 T 09-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 UA74_RS27185 4bce5c56a21e599cbb401be76c8ad8bd 504 Gene3D G3DSA:3.30.420.40 2 255 2.9E-103 T 09-03-2017 UA74_RS23275 6d5e9e641bbc2c437b7952c8e2c0630b 381 Pfam PF09344 CT1975-like protein 9 368 2.8E-104 T 09-03-2017 IPR010148 CRISPR-associated protein, CT1975 UA74_RS23275 6d5e9e641bbc2c437b7952c8e2c0630b 381 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 8 333 2.3E-94 T 09-03-2017 IPR010148 CRISPR-associated protein, CT1975 UA74_RS18400 d22e8994c5c14bb602165561086b4d32 264 Pfam PF00722 Glycosyl hydrolases family 16 68 238 1.3E-6 T 09-03-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 UA74_RS18400 d22e8994c5c14bb602165561086b4d32 264 SUPERFAMILY SSF49899 24 243 6.86E-19 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS18400 d22e8994c5c14bb602165561086b4d32 264 Gene3D G3DSA:2.60.120.200 24 246 8.8E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 369 537 1.0E-55 T 09-03-2017 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 Gene3D G3DSA:2.60.120.260 540 644 6.6E-14 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 Pfam PF05592 Bacterial alpha-L-rhamnosidase 547 1054 1.1E-155 T 09-03-2017 IPR008902 Bacterial alpha-L-rhamnosidase UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 SUPERFAMILY SSF49265 72 159 3.71E-6 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 SUPERFAMILY SSF49785 308 435 1.09E-5 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 Gene3D G3DSA:2.60.40.10 73 159 1.4E-6 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 SUPERFAMILY SSF48208 672 1056 3.74E-38 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS20450 d306727b4ce64250970da2e956e6f695 1094 PIRSF PIRSF010631 42 1094 5.9E-295 T 09-03-2017 IPR016007 Alpha-L-rhamnosidase UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:3.40.1440.10 17 95 3.5E-10 T 09-03-2017 IPR027299 GIY-YIG domain UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 458 691 2.5E-44 T 09-03-2017 IPR001162 UvrC family homology region UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF14520 Helix-hairpin-helix domain 707 757 8.8E-9 T 09-03-2017 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF01541 GIY-YIG catalytic domain 18 92 7.2E-10 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:4.10.860.10 187 248 1.4E-19 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 SMART SM00465 17 99 3.4E-20 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 756 29.569 T 09-03-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:1.10.150.20 704 758 5.4E-20 T 09-03-2017 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 SMART SM00278 705 724 20.0 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 SMART SM00278 737 756 27.0 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 SUPERFAMILY SSF47781 650 758 3.08E-23 T 09-03-2017 IPR010994 RuvA domain 2-like UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 SUPERFAMILY SSF46600 195 247 4.58E-14 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF02151 UvrB/uvrC motif 209 242 4.0E-10 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS12420 0b0cc35614941dc6328c46c39251ef7a 774 SUPERFAMILY SSF82771 17 101 7.59E-22 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 Gene3D G3DSA:3.20.20.70 11 360 3.3E-106 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 SUPERFAMILY SSF110921 422 538 7.19E-25 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 Pfam PF08502 LeuA allosteric (dimerisation) domain 388 538 1.2E-24 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 SMART SM00917 387 542 2.5E-36 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 SUPERFAMILY SSF51569 11 305 2.38E-72 T 09-03-2017 UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 16 548 1.5E-175 T 09-03-2017 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 Pfam PF00682 HMGL-like 16 267 3.7E-40 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_RS26100 a313cbd0b0a4a55bef03d92bb121f889 552 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 22 38 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS12390 f0999ba4b0d0249a55f6040055bfa593 232 Gene3D G3DSA:3.20.20.70 1 219 1.9E-84 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS12390 f0999ba4b0d0249a55f6040055bfa593 232 Pfam PF00834 Ribulose-phosphate 3 epimerase family 2 202 2.1E-75 T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS12390 f0999ba4b0d0249a55f6040055bfa593 232 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 1 215 9.0E-80 T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS12390 f0999ba4b0d0249a55f6040055bfa593 232 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS12390 f0999ba4b0d0249a55f6040055bfa593 232 PIRSF PIRSF001461 1 226 9.7E-87 T 09-03-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS12390 f0999ba4b0d0249a55f6040055bfa593 232 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 09-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_RS12390 f0999ba4b0d0249a55f6040055bfa593 232 SUPERFAMILY SSF51366 2 216 5.23E-60 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 UA74_RS23715 83ccb2a833ea043f16bc8ca6f5f162ec 393 Pfam PF00202 Aminotransferase class-III 10 391 1.8E-114 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS23715 83ccb2a833ea043f16bc8ca6f5f162ec 393 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 2 391 4.1E-138 T 09-03-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_RS23715 83ccb2a833ea043f16bc8ca6f5f162ec 393 SUPERFAMILY SSF53383 3 392 2.66E-118 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS23715 83ccb2a833ea043f16bc8ca6f5f162ec 393 Gene3D G3DSA:3.40.640.10 52 296 4.0E-82 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS23715 83ccb2a833ea043f16bc8ca6f5f162ec 393 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS23715 83ccb2a833ea043f16bc8ca6f5f162ec 393 Gene3D G3DSA:3.90.1150.10 301 392 2.1E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS23715 83ccb2a833ea043f16bc8ca6f5f162ec 393 Gene3D G3DSA:3.90.1150.10 5 51 2.1E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS27010 f5eab08174810628bed511ad33f1cbe2 267 Gene3D G3DSA:3.90.550.10 8 235 7.2E-59 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS27010 f5eab08174810628bed511ad33f1cbe2 267 Pfam PF00483 Nucleotidyl transferase 10 234 2.3E-28 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_RS27010 f5eab08174810628bed511ad33f1cbe2 267 SUPERFAMILY SSF53448 5 234 9.81E-58 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 Hamap MF_00318 Enolase [eno]. 2 409 45.533 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 6.3E-206 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 SUPERFAMILY SSF51604 138 421 7.34E-128 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 09-03-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 SMART SM01192 139 423 1.6E-216 T 09-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 Pfam PF03952 Enolase, N-terminal domain 4 134 1.5E-56 T 09-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 361 378 2.6E-48 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 161 174 2.6E-48 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 309 320 2.6E-48 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 332 346 2.6E-48 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 107 123 2.6E-48 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 37 51 2.6E-48 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 Gene3D G3DSA:3.20.20.120 129 421 1.8E-133 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 Gene3D G3DSA:3.30.390.10 4 126 3.2E-53 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 SMART SM01193 4 134 5.7E-86 T 09-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 418 9.1E-132 T 09-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 PIRSF PIRSF001400 1 422 2.6E-192 T 09-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03740 e19f7f8a6827ba8270174224187e5458 428 SUPERFAMILY SSF54826 4 136 1.7E-51 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS14370 46df8bd0287442e941beaa185047ab9e 153 SUPERFAMILY SSF46785 6 147 3.52E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14370 46df8bd0287442e941beaa185047ab9e 153 Pfam PF12802 MarR family 39 98 1.2E-8 T 09-03-2017 UA74_RS14370 46df8bd0287442e941beaa185047ab9e 153 SMART SM00347 33 136 6.5E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS14370 46df8bd0287442e941beaa185047ab9e 153 Gene3D G3DSA:1.10.10.10 2 147 2.6E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 Gene3D G3DSA:3.40.50.720 6 251 5.8E-83 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 SUPERFAMILY SSF51735 7 252 6.0E-77 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 7 253 1.6E-104 T 09-03-2017 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.12+1.1.1.127|MetaCyc: PWY-5515|MetaCyc: PWY-6507|MetaCyc: PWY-7562 UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 179 0.003 T 09-03-2017 UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 250 2.1E-58 T 09-03-2017 UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.1E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.1E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.6E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.6E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.6E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.6E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.6E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21170 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.6E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:4.10.870.10 798 869 7.1E-28 T 09-03-2017 IPR027390 Endoglucanase F, domain 3 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Pfam PF02011 Glycosyl hydrolase family 48 257 891 5.7E-289 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Pfam PF00553 Cellulose binding domain 42 142 4.8E-36 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:1.50.10.10 387 402 7.6E-183 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:1.50.10.10 477 795 7.6E-183 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:1.50.10.10 870 891 7.6E-183 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:1.50.10.10 253 341 7.6E-183 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:2.60.40.290 41 142 2.1E-38 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 107 120 - T 09-03-2017 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 283 308 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 660 686 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 470 497 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 824 852 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 614 637 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 715 735 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 309 326 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 425 449 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 543 562 1.5E-93 T 09-03-2017 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 SUPERFAMILY SSF48208 253 893 5.02E-267 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 SMART SM00637 42 142 1.8E-49 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS21120 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 SUPERFAMILY SSF49384 41 142 9.07E-32 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS13910 62c03dff1aa6b2f446bdcb3b3c7dc933 102 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 7 93 1.6E-16 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_RS13910 62c03dff1aa6b2f446bdcb3b3c7dc933 102 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 7 101 15.05 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_RS13910 62c03dff1aa6b2f446bdcb3b3c7dc933 102 Pfam PF09827 CRISPR associated protein Cas2 7 79 4.1E-19 T 09-03-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 UA74_RS13910 62c03dff1aa6b2f446bdcb3b3c7dc933 102 Gene3D G3DSA:3.30.70.240 7 77 6.6E-23 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS13910 62c03dff1aa6b2f446bdcb3b3c7dc933 102 SUPERFAMILY SSF143430 6 90 6.02E-22 T 09-03-2017 UA74_RS13910 62c03dff1aa6b2f446bdcb3b3c7dc933 102 PIRSF PIRSF032582 7 102 6.6E-31 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_RS10805 41d5251f075520b93624006c80af7167 211 Gene3D G3DSA:3.40.630.30 1 192 1.9E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS10805 41d5251f075520b93624006c80af7167 211 Pfam PF00583 Acetyltransferase (GNAT) family 105 168 4.5E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS10805 41d5251f075520b93624006c80af7167 211 SUPERFAMILY SSF55729 4 193 2.79E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS03535 faf752a621fb1d7cd7c6158da43724b7 222 Pfam PF00106 short chain dehydrogenase 4 138 2.3E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS03535 faf752a621fb1d7cd7c6158da43724b7 222 Gene3D G3DSA:3.40.50.720 3 188 1.3E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03535 faf752a621fb1d7cd7c6158da43724b7 222 SUPERFAMILY SSF51735 3 190 1.79E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03535 faf752a621fb1d7cd7c6158da43724b7 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 175 1.6E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS03535 faf752a621fb1d7cd7c6158da43724b7 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 116 1.6E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS03535 faf752a621fb1d7cd7c6158da43724b7 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 26 1.6E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS03535 faf752a621fb1d7cd7c6158da43724b7 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 134 1.6E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS19710 c3eb2a5a4a106e856f8f7d56c2fc0794 227 Pfam PF00005 ABC transporter 16 152 1.7E-21 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS19710 c3eb2a5a4a106e856f8f7d56c2fc0794 227 SMART SM00382 23 201 3.6E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS19710 c3eb2a5a4a106e856f8f7d56c2fc0794 227 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS19710 c3eb2a5a4a106e856f8f7d56c2fc0794 227 SUPERFAMILY SSF52540 2 215 2.38E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19710 c3eb2a5a4a106e856f8f7d56c2fc0794 227 Gene3D G3DSA:3.40.50.300 1 218 1.9E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02860 f1f59bb88c54b73b701906c71f54ec45 286 Pfam PF13560 Helix-turn-helix domain 13 70 1.1E-8 T 09-03-2017 UA74_RS02860 f1f59bb88c54b73b701906c71f54ec45 286 SUPERFAMILY SSF47413 9 72 5.07E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02860 f1f59bb88c54b73b701906c71f54ec45 286 Gene3D G3DSA:1.10.260.40 5 70 1.8E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02860 f1f59bb88c54b73b701906c71f54ec45 286 SMART SM00530 16 71 1.4E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS06335 1017b069f9bd1c5226f9ecc09193508f 256 Pfam PF12706 Beta-lactamase superfamily domain 48 223 1.8E-20 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS06335 1017b069f9bd1c5226f9ecc09193508f 256 SMART SM00849 18 193 3.0E-7 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS06335 1017b069f9bd1c5226f9ecc09193508f 256 SUPERFAMILY SSF56281 3 254 4.98E-47 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS06335 1017b069f9bd1c5226f9ecc09193508f 256 Gene3D G3DSA:3.60.15.10 3 252 7.2E-52 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS20685 e8d8bc86f5b463e32e6557e1e100f4d8 372 Gene3D G3DSA:2.115.10.20 15 330 1.0E-83 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS20685 e8d8bc86f5b463e32e6557e1e100f4d8 372 Pfam PF04616 Glycosyl hydrolases family 43 18 313 1.5E-54 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_RS20685 e8d8bc86f5b463e32e6557e1e100f4d8 372 SUPERFAMILY SSF75005 17 330 8.57E-57 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS25490 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 Gene3D G3DSA:3.40.30.10 2 152 9.3E-48 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS25490 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 Pfam PF00578 AhpC/TSA family 5 130 1.8E-36 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS25490 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 SUPERFAMILY SSF52833 1 152 5.79E-46 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS25490 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 PIRSF PIRSF000239 1 151 1.1E-23 T 09-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS16150 d99fe5bd1f83bc61681336f30a35d087 171 Pfam PF06114 Domain of unknown function (DUF955) 66 138 2.5E-4 T 09-03-2017 IPR010359 HTH domain, IrrE-type UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 255 266 1.4E-9 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 223 235 1.4E-9 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 240 255 1.4E-9 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 78 91 1.4E-9 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Gene3D G3DSA:1.10.10.10 208 269 1.4E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 SUPERFAMILY SSF88659 203 269 2.62E-16 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 SUPERFAMILY SSF88946 31 124 6.67E-31 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Gene3D G3DSA:1.10.601.10 46 121 2.8E-23 T 09-03-2017 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Pfam PF04545 Sigma-70, region 4 219 268 3.3E-17 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Gene3D G3DSA:1.10.10.10 122 176 4.1E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Pfam PF04542 Sigma-70 region 2 54 124 4.4E-20 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Pfam PF04539 Sigma-70 region 3 138 192 1.1E-11 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 269 6.2E-40 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 48 270 1.6E-90 T 09-03-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS21350 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 SUPERFAMILY SSF88659 127 200 6.1E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS03695 344d995ac828eb8694f5f66efff5b8ee 340 Gene3D G3DSA:1.10.287.1080 129 184 4.3E-11 T 09-03-2017 UA74_RS03695 344d995ac828eb8694f5f66efff5b8ee 340 TIGRFAM TIGR00444 mazG: MazG family protein 119 262 5.9E-44 T 09-03-2017 IPR011551 NTP pyrophosphohydrolase MazG UA74_RS03695 344d995ac828eb8694f5f66efff5b8ee 340 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 135 210 1.4E-24 T 09-03-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UA74_RS03695 344d995ac828eb8694f5f66efff5b8ee 340 SUPERFAMILY SSF101386 116 213 1.8E-22 T 09-03-2017 UA74_RS09290 3379901fb088320e7f4aeca180750e05 345 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 13 336 1.8E-136 T 09-03-2017 IPR019949 Luciferase family oxidoreductase, group 1 UA74_RS09290 3379901fb088320e7f4aeca180750e05 345 Gene3D G3DSA:3.20.20.30 12 336 5.0E-96 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS09290 3379901fb088320e7f4aeca180750e05 345 SUPERFAMILY SSF51679 12 336 3.79E-82 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS09290 3379901fb088320e7f4aeca180750e05 345 Pfam PF00296 Luciferase-like monooxygenase 25 313 1.8E-37 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS28585 c02ac44021fc56fb43718c31a1e00a85 226 Pfam PF01476 LysM domain 181 225 6.8E-12 T 09-03-2017 IPR018392 LysM domain UA74_RS28585 c02ac44021fc56fb43718c31a1e00a85 226 Gene3D G3DSA:3.10.350.10 181 225 2.8E-12 T 09-03-2017 IPR018392 LysM domain UA74_RS28585 c02ac44021fc56fb43718c31a1e00a85 226 SMART SM00257 180 226 5.2E-10 T 09-03-2017 IPR018392 LysM domain UA74_RS28585 c02ac44021fc56fb43718c31a1e00a85 226 Pfam PF06737 Transglycosylase-like domain 41 114 1.0E-35 T 09-03-2017 IPR010618 Transglycosylase-like UA74_RS28585 c02ac44021fc56fb43718c31a1e00a85 226 SUPERFAMILY SSF54106 181 225 1.57E-8 T 09-03-2017 IPR018392 LysM domain UA74_RS28585 c02ac44021fc56fb43718c31a1e00a85 226 Gene3D G3DSA:1.10.530.10 22 119 1.2E-41 T 09-03-2017 UA74_RS28585 c02ac44021fc56fb43718c31a1e00a85 226 SUPERFAMILY SSF53955 40 120 9.09E-33 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS27295 caaf84692dd6635d2dcfd5413b5e1984 355 Gene3D G3DSA:3.40.50.2300 52 168 2.2E-25 T 09-03-2017 UA74_RS27295 caaf84692dd6635d2dcfd5413b5e1984 355 Pfam PF13407 Periplasmic binding protein domain 58 315 1.6E-39 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS27295 caaf84692dd6635d2dcfd5413b5e1984 355 Gene3D G3DSA:3.40.50.2300 169 348 4.1E-26 T 09-03-2017 UA74_RS27295 caaf84692dd6635d2dcfd5413b5e1984 355 SUPERFAMILY SSF53822 55 348 2.36E-53 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS28435 aa4c49e91439b94ab01d595d299de3b1 378 Pfam PF00266 Aminotransferase class-V 39 336 2.1E-12 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS28435 aa4c49e91439b94ab01d595d299de3b1 378 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 18 377 3.4E-193 T 09-03-2017 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 UA74_RS28435 aa4c49e91439b94ab01d595d299de3b1 378 Gene3D G3DSA:3.40.640.10 26 270 1.1E-50 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS28435 aa4c49e91439b94ab01d595d299de3b1 378 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 11 377 23.895 T 09-03-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 UA74_RS28435 aa4c49e91439b94ab01d595d299de3b1 378 SUPERFAMILY SSF53383 23 376 2.96E-72 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS28435 aa4c49e91439b94ab01d595d299de3b1 378 PIRSF PIRSF000525 11 377 2.1E-76 T 09-03-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 UA74_RS15475 de90433aee24b2741ade64150158d40f 408 Pfam PF07690 Major Facilitator Superfamily 9 329 1.6E-36 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS15475 de90433aee24b2741ade64150158d40f 408 SUPERFAMILY SSF103473 3 395 3.66E-51 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15475 de90433aee24b2741ade64150158d40f 408 Gene3D G3DSA:1.20.1250.20 5 181 6.1E-25 T 09-03-2017 UA74_RS15475 de90433aee24b2741ade64150158d40f 408 Gene3D G3DSA:1.20.1250.20 209 383 1.1E-14 T 09-03-2017 UA74_RS05880 891d5f6e8470f12bdd4168eec3289e9e 328 SUPERFAMILY SSF51735 1 317 1.21E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05880 891d5f6e8470f12bdd4168eec3289e9e 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 238 7.3E-36 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS05880 891d5f6e8470f12bdd4168eec3289e9e 328 Gene3D G3DSA:3.40.50.720 1 189 4.9E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05880 891d5f6e8470f12bdd4168eec3289e9e 328 Gene3D G3DSA:3.90.25.10 190 315 2.2E-17 T 09-03-2017 UA74_RS14740 ffb9b8ef2af490b2830c4f626054a2b9 267 Gene3D G3DSA:3.90.1200.10 20 197 1.4E-17 T 09-03-2017 UA74_RS14740 ffb9b8ef2af490b2830c4f626054a2b9 267 SUPERFAMILY SSF56112 16 197 9.48E-23 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS14740 ffb9b8ef2af490b2830c4f626054a2b9 267 Pfam PF01636 Phosphotransferase enzyme family 112 184 4.3E-8 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS30060 60ad4d87c81a4d97c981d02a02ab4aee 272 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS30060 60ad4d87c81a4d97c981d02a02ab4aee 272 PIRSF PIRSF039085 18 261 2.3E-111 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UA74_RS30060 60ad4d87c81a4d97c981d02a02ab4aee 272 Gene3D G3DSA:3.40.50.300 20 256 6.3E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30060 60ad4d87c81a4d97c981d02a02ab4aee 272 Pfam PF00005 ABC transporter 37 185 7.8E-34 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS30060 60ad4d87c81a4d97c981d02a02ab4aee 272 SUPERFAMILY SSF52540 21 255 7.99E-77 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30060 60ad4d87c81a4d97c981d02a02ab4aee 272 SMART SM00382 46 233 1.1E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 SUPERFAMILY SSF47203 237 380 2.09E-10 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 Gene3D G3DSA:1.20.140.10 201 390 2.9E-37 T 09-03-2017 UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 Gene3D G3DSA:2.40.110.10 117 200 2.9E-24 T 09-03-2017 UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 Gene3D G3DSA:1.10.540.10 5 112 1.2E-31 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 PIRSF PIRSF016578 2 393 4.0E-116 T 09-03-2017 UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 88 2.0E-4 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 SUPERFAMILY SSF56645 9 208 1.83E-31 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS17670 0cddab9e1fd82d46e9747919ffb492de 393 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 371 3.8E-20 T 09-03-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 Gene3D G3DSA:3.30.70.360 181 272 3.7E-20 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 7 356 3.4E-154 T 09-03-2017 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 Pfam PF07687 Peptidase dimerisation domain 172 269 4.1E-12 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 SUPERFAMILY SSF53187 9 184 5.74E-41 T 09-03-2017 UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 SUPERFAMILY SSF53187 282 356 5.74E-41 T 09-03-2017 UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 SUPERFAMILY SSF55031 172 273 2.54E-18 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 Gene3D G3DSA:3.40.630.10 9 180 9.4E-44 T 09-03-2017 UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 Gene3D G3DSA:3.40.630.10 301 356 9.4E-44 T 09-03-2017 UA74_RS04465 7154989cb23de8200667a1dbd47a6292 357 Pfam PF01546 Peptidase family M20/M25/M40 68 356 2.5E-21 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS30415 36ee80a334ec29cc59f273aaeb2c4884 214 SUPERFAMILY SSF55729 33 141 2.93E-10 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS30415 36ee80a334ec29cc59f273aaeb2c4884 214 Pfam PF00583 Acetyltransferase (GNAT) family 66 138 5.7E-5 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS30415 36ee80a334ec29cc59f273aaeb2c4884 214 Gene3D G3DSA:3.40.630.30 40 168 1.9E-9 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS17740 e2c1905c3af6dbfcc79c58a8862bf214 324 Pfam PF01867 CRISPR associated protein Cas1 50 137 3.3E-6 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS17740 e2c1905c3af6dbfcc79c58a8862bf214 324 Pfam PF01867 CRISPR associated protein Cas1 147 252 1.8E-12 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS17740 e2c1905c3af6dbfcc79c58a8862bf214 324 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 148 254 1.9E-22 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS17740 e2c1905c3af6dbfcc79c58a8862bf214 324 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 8 303 17.868 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS17740 e2c1905c3af6dbfcc79c58a8862bf214 324 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 17 285 8.3E-100 T 09-03-2017 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 SMART SM00421 150 207 3.7E-22 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 Gene3D G3DSA:1.10.10.10 124 214 6.9E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 Pfam PF00072 Response regulator receiver domain 5 116 4.0E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 9.8E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 5.4E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 5.4E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 5.4E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 SMART SM00448 3 115 6.8E-33 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 SUPERFAMILY SSF52172 2 131 3.7E-34 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 SUPERFAMILY SSF46894 141 213 4.08E-21 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS24050 dc8e1018548fdc600843e0d7787e5b9e 221 Gene3D G3DSA:3.40.50.2300 1 123 1.5E-39 T 09-03-2017 UA74_RS28215 cae12d0696d5337e793a6222051a3f45 203 Gene3D G3DSA:3.30.230.10 79 203 8.7E-49 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS28215 cae12d0696d5337e793a6222051a3f45 203 SUPERFAMILY SSF54211 79 203 7.59E-44 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS28215 cae12d0696d5337e793a6222051a3f45 203 Pfam PF00380 Ribosomal protein S9/S16 83 203 8.4E-44 T 09-03-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 UA74_RS28215 cae12d0696d5337e793a6222051a3f45 203 ProSitePatterns PS00360 Ribosomal protein S9 signature. 142 160 - T 09-03-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 UA74_RS28215 cae12d0696d5337e793a6222051a3f45 203 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 74 203 32.278 T 09-03-2017 IPR023035 Ribosomal protein S9, bacterial/plastid UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 14 391 1.5E-192 T 09-03-2017 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 Pfam PF01261 Xylose isomerase-like TIM barrel 52 276 6.2E-25 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 Gene3D G3DSA:3.20.20.150 15 394 1.7E-134 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 Hamap MF_00455 Xylose isomerase [xylA]. 12 391 34.678 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 140 161 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 167 186 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 231 258 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 259 270 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 56 78 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 116 135 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 93 113 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 292 303 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 189 213 4.4E-64 T 09-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_RS27285 dbb63b6d67aa7d8d0f2d970045be8b0e 396 SUPERFAMILY SSF51658 15 395 2.49E-115 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS06340 4a6261a6e161030c8a6084c480f34605 320 Gene3D G3DSA:1.20.58.340 246 320 4.4E-15 T 09-03-2017 UA74_RS06340 4a6261a6e161030c8a6084c480f34605 320 Pfam PF01544 CorA-like Mg2+ transporter protein 33 316 7.0E-60 T 09-03-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 UA74_RS06340 4a6261a6e161030c8a6084c480f34605 320 SUPERFAMILY SSF143865 5 255 4.45E-62 T 09-03-2017 UA74_RS06340 4a6261a6e161030c8a6084c480f34605 320 Gene3D G3DSA:3.30.460.20 4 128 8.7E-25 T 09-03-2017 UA74_RS06340 4a6261a6e161030c8a6084c480f34605 320 Gene3D G3DSA:1.20.58.340 130 242 1.4E-35 T 09-03-2017 UA74_RS06340 4a6261a6e161030c8a6084c480f34605 320 SUPERFAMILY SSF144083 256 317 1.57E-11 T 09-03-2017 UA74_RS17060 b1608edff45929033f54ae091975f449 404 SUPERFAMILY SSF51338 12 63 2.44E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17060 b1608edff45929033f54ae091975f449 404 SUPERFAMILY SSF51338 364 402 2.44E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17060 b1608edff45929033f54ae091975f449 404 Gene3D G3DSA:2.30.40.10 9 64 7.4E-16 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17060 b1608edff45929033f54ae091975f449 404 Gene3D G3DSA:2.30.40.10 364 402 7.4E-16 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17060 b1608edff45929033f54ae091975f449 404 Pfam PF01979 Amidohydrolase family 59 402 1.4E-40 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS17060 b1608edff45929033f54ae091975f449 404 Gene3D G3DSA:3.20.20.140 65 360 9.2E-77 T 09-03-2017 UA74_RS17060 b1608edff45929033f54ae091975f449 404 SUPERFAMILY SSF51556 63 364 1.92E-76 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS08205 d3d70b4fda6dffde176fe9122d77db42 473 Gene3D G3DSA:1.20.1250.20 238 433 2.8E-15 T 09-03-2017 UA74_RS08205 d3d70b4fda6dffde176fe9122d77db42 473 Gene3D G3DSA:1.20.1250.20 18 212 9.0E-14 T 09-03-2017 UA74_RS08205 d3d70b4fda6dffde176fe9122d77db42 473 SUPERFAMILY SSF103473 16 437 3.92E-42 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS08205 d3d70b4fda6dffde176fe9122d77db42 473 Pfam PF07690 Major Facilitator Superfamily 34 389 4.6E-25 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:3.40.980.10 161 329 2.5E-46 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:2.40.340.10 330 400 7.1E-22 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 SUPERFAMILY SSF63882 1 174 1.44E-45 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 Pfam PF03454 MoeA C-terminal region (domain IV) 331 403 4.5E-20 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 SMART SM00852 178 317 5.9E-22 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 165 2.9E-30 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:2.170.190.11 44 129 4.1E-32 T 09-03-2017 UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 Pfam PF00994 Probable molybdopterin binding domain 179 316 2.4E-16 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 SUPERFAMILY SSF53218 175 321 2.75E-30 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:3.90.105.10 130 160 6.3E-16 T 09-03-2017 UA74_RS03275 deb243806c58c6e58ee68bb872a36cd7 407 SUPERFAMILY SSF63867 326 403 2.22E-18 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS27795 e35f8b55992e09e5158bebf8c1b9fae9 413 SUPERFAMILY SSF103473 3 403 1.96E-29 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS27795 e35f8b55992e09e5158bebf8c1b9fae9 413 Gene3D G3DSA:1.20.1250.20 12 173 1.4E-9 T 09-03-2017 UA74_RS27795 e35f8b55992e09e5158bebf8c1b9fae9 413 Gene3D G3DSA:1.20.1250.20 228 404 3.6E-13 T 09-03-2017 UA74_RS27795 e35f8b55992e09e5158bebf8c1b9fae9 413 Pfam PF07690 Major Facilitator Superfamily 13 220 3.0E-9 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS11120 6b19db4adc5d29e0ae5edd6950cfbfb0 181 SUPERFAMILY SSF51230 101 176 2.75E-20 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS11120 6b19db4adc5d29e0ae5edd6950cfbfb0 181 Pfam PF00364 Biotin-requiring enzyme 103 174 3.8E-15 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS11120 6b19db4adc5d29e0ae5edd6950cfbfb0 181 Gene3D G3DSA:2.40.50.100 101 176 2.0E-23 T 09-03-2017 UA74_RS11120 6b19db4adc5d29e0ae5edd6950cfbfb0 181 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 122 136 8.1E-13 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UA74_RS11120 6b19db4adc5d29e0ae5edd6950cfbfb0 181 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 105 118 8.1E-13 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UA74_RS11120 6b19db4adc5d29e0ae5edd6950cfbfb0 181 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 137 150 8.1E-13 T 09-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 Gene3D G3DSA:3.40.50.2300 182 331 1.3E-37 T 09-03-2017 UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 54 5.0E-7 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 Pfam PF13377 Periplasmic binding protein-like domain 179 352 5.5E-27 T 09-03-2017 UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 Gene3D G3DSA:1.10.260.40 10 62 3.2E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 Gene3D G3DSA:3.40.50.2300 63 181 9.7E-23 T 09-03-2017 UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 SMART SM00354 10 81 6.6E-12 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 SUPERFAMILY SSF53822 83 347 4.32E-46 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS01770 e60d88c653bf74902d37bdf89420381f 366 SUPERFAMILY SSF47413 10 68 4.03E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 SUPERFAMILY SSF50249 14 91 6.43E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 14 85 1.0E-28 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 Pfam PF00366 Ribosomal protein S17 19 86 1.0E-28 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 ProSitePatterns PS00056 Ribosomal protein S17 signature. 65 77 - T 09-03-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 Gene3D G3DSA:2.40.50.140 14 91 1.4E-32 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 14 85 2.0E-32 T 09-03-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 12 90 23.723 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 PRINTS PR00973 Ribosomal protein S17 family signature 33 56 3.6E-10 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 PRINTS PR00973 Ribosomal protein S17 family signature 75 82 3.6E-10 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02975 d543c74f8b44dfeccce5ab88e19b5de6 92 PRINTS PR00973 Ribosomal protein S17 family signature 65 75 3.6E-10 T 09-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS25895 76b02d1b48e53448a7700d63fde4587e 63 SUPERFAMILY SSF143800 2 62 9.22E-22 T 09-03-2017 UA74_RS25895 76b02d1b48e53448a7700d63fde4587e 63 Pfam PF00830 Ribosomal L28 family 4 59 2.1E-21 T 09-03-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS25895 76b02d1b48e53448a7700d63fde4587e 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 1.1E-20 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS25895 76b02d1b48e53448a7700d63fde4587e 63 Gene3D G3DSA:4.10.1160.10 19 62 3.4E-22 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS25895 76b02d1b48e53448a7700d63fde4587e 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 15.995 T 09-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS14575 06b51b7218703d7fca4152357cf822cf 523 Gene3D G3DSA:1.20.1250.20 459 491 1.5E-17 T 09-03-2017 UA74_RS14575 06b51b7218703d7fca4152357cf822cf 523 Gene3D G3DSA:1.20.1250.20 260 426 1.5E-17 T 09-03-2017 UA74_RS14575 06b51b7218703d7fca4152357cf822cf 523 Pfam PF07690 Major Facilitator Superfamily 22 414 1.1E-48 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS14575 06b51b7218703d7fca4152357cf822cf 523 SUPERFAMILY SSF103473 8 200 5.75E-53 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14575 06b51b7218703d7fca4152357cf822cf 523 SUPERFAMILY SSF103473 457 483 5.75E-53 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14575 06b51b7218703d7fca4152357cf822cf 523 SUPERFAMILY SSF103473 251 425 5.75E-53 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14575 06b51b7218703d7fca4152357cf822cf 523 Gene3D G3DSA:1.20.1250.20 18 196 8.7E-25 T 09-03-2017 UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 277 427 1.3E-47 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 55 575 1.1E-256 T 09-03-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 SMART SM00382 273 429 9.8E-22 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 SUPERFAMILY SSF52540 485 546 2.14E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 SUPERFAMILY SSF52540 235 444 2.14E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 ProSitePatterns PS00674 AAA-protein family signature. 397 415 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 57 576 50.861 T 09-03-2017 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 Gene3D G3DSA:3.40.50.300 227 442 1.3E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12950 6f9807d63cde95d3a16a9571b193d1b3 597 Pfam PF16450 Proteasomal ATPase OB/ID domain 99 234 1.2E-52 T 09-03-2017 IPR032501 Proteasomal ATPase, OB/ID domain UA74_RS26350 60e22a4b6cf17fee7e86152934390bc2 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 7.3E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26350 60e22a4b6cf17fee7e86152934390bc2 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.4E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26350 60e22a4b6cf17fee7e86152934390bc2 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.4E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26350 60e22a4b6cf17fee7e86152934390bc2 186 Gene3D G3DSA:1.10.357.10 3 172 4.7E-29 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS26350 60e22a4b6cf17fee7e86152934390bc2 186 SUPERFAMILY SSF46689 3 69 3.34E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 SUPERFAMILY SSF52518 79 495 1.29E-129 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 159 323 2.0E-9 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 29 920 0.0 T 09-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 Gene3D G3DSA:3.40.50.970 501 739 4.7E-108 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 PIRSF PIRSF000156 19 924 0.0 T 09-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 SUPERFAMILY SSF52922 738 916 7.15E-48 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 SUPERFAMILY SSF52518 502 735 1.38E-84 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 Gene3D G3DSA:3.40.50.920 743 919 8.8E-63 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS25500 38d6de5b6002d6bc433ae95127c4290c 930 Gene3D G3DSA:3.40.50.970 79 497 5.0E-152 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 Pfam PF04542 Sigma-70 region 2 32 96 1.5E-12 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 Gene3D G3DSA:1.10.1740.10 8 115 2.7E-23 T 09-03-2017 UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 52 83 - T 09-03-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 183 8.3E-22 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 Pfam PF08281 Sigma-70, region 4 131 180 3.9E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 SUPERFAMILY SSF88659 126 183 1.25E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 SUPERFAMILY SSF88946 7 109 2.75E-22 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS17220 ae778bf14e611a133b471b22582573a7 192 Gene3D G3DSA:1.10.10.10 130 183 2.3E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12350 3d0c7b4becd7cfff2b836f8ad8e997e5 255 Pfam PF08241 Methyltransferase domain 45 131 1.1E-13 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS12350 3d0c7b4becd7cfff2b836f8ad8e997e5 255 SUPERFAMILY SSF53335 26 170 6.48E-21 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12350 3d0c7b4becd7cfff2b836f8ad8e997e5 255 Gene3D G3DSA:3.40.50.150 39 156 5.7E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06180 edf518184c2c5000b1f848e327bb601d 248 Gene3D G3DSA:3.40.50.300 11 230 4.1E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06180 edf518184c2c5000b1f848e327bb601d 248 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS06180 edf518184c2c5000b1f848e327bb601d 248 SMART SM00382 40 226 9.5E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS06180 edf518184c2c5000b1f848e327bb601d 248 SUPERFAMILY SSF52540 12 229 2.37E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06180 edf518184c2c5000b1f848e327bb601d 248 Pfam PF00005 ABC transporter 31 177 6.8E-34 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS19305 ca8c174d518ab014a218b28a4e315a4f 231 Gene3D G3DSA:1.10.10.10 124 219 1.2E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19305 ca8c174d518ab014a218b28a4e315a4f 231 SMART SM00862 145 217 2.4E-20 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS19305 ca8c174d518ab014a218b28a4e315a4f 231 SMART SM00448 1 112 4.9E-29 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS19305 ca8c174d518ab014a218b28a4e315a4f 231 Pfam PF00072 Response regulator receiver domain 3 112 6.2E-21 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS19305 ca8c174d518ab014a218b28a4e315a4f 231 SUPERFAMILY SSF52172 1 170 1.06E-33 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS19305 ca8c174d518ab014a218b28a4e315a4f 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 217 1.3E-19 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS19305 ca8c174d518ab014a218b28a4e315a4f 231 Gene3D G3DSA:3.40.50.2300 1 123 4.2E-29 T 09-03-2017 UA74_RS10445 265d86e4b4544716969e3220a461fb76 280 Gene3D G3DSA:3.40.50.1820 5 278 8.3E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10445 265d86e4b4544716969e3220a461fb76 280 Pfam PF00561 alpha/beta hydrolase fold 23 259 6.3E-24 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS10445 265d86e4b4544716969e3220a461fb76 280 SUPERFAMILY SSF53474 7 277 1.26E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10445 265d86e4b4544716969e3220a461fb76 280 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 25 33 2.6E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS10445 265d86e4b4544716969e3220a461fb76 280 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 91 105 2.6E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS10445 265d86e4b4544716969e3220a461fb76 280 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 62 2.6E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS09635 75ee5b989e648d5c0a9543d89d347975 422 Pfam PF00860 Permease family 31 386 4.8E-74 T 09-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS03615 2c8e7d6a79c4352f11403f4711d7d090 192 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 19 32 - T 09-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 UA74_RS03615 2c8e7d6a79c4352f11403f4711d7d090 192 Gene3D G3DSA:3.40.50.1470 4 191 1.7E-73 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_RS03615 2c8e7d6a79c4352f11403f4711d7d090 192 SUPERFAMILY SSF53178 6 190 1.28E-65 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_RS03615 2c8e7d6a79c4352f11403f4711d7d090 192 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 09-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 UA74_RS03615 2c8e7d6a79c4352f11403f4711d7d090 192 Pfam PF01195 Peptidyl-tRNA hydrolase 8 189 3.9E-55 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_RS03615 2c8e7d6a79c4352f11403f4711d7d090 192 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 7 190 4.2E-57 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_RS03615 2c8e7d6a79c4352f11403f4711d7d090 192 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 6 183 33.261 T 09-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_RS00710 ec99ce4960fa12e37ebc472c1f420a98 220 SUPERFAMILY SSF53335 38 207 6.66E-8 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00710 ec99ce4960fa12e37ebc472c1f420a98 220 Gene3D G3DSA:3.40.50.150 56 201 8.0E-8 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00710 ec99ce4960fa12e37ebc472c1f420a98 220 Pfam PF13578 Methyltransferase domain 54 185 4.1E-13 T 09-03-2017 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 SUPERFAMILY SSF47413 2 60 2.35E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 Gene3D G3DSA:1.10.260.40 2 53 1.2E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 SMART SM00354 1 71 6.1E-19 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 8.9E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 Gene3D G3DSA:3.40.50.2300 173 311 1.4E-24 T 09-03-2017 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 Gene3D G3DSA:3.40.50.2300 54 172 1.4E-22 T 09-03-2017 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 Pfam PF13377 Periplasmic binding protein-like domain 168 330 3.0E-27 T 09-03-2017 UA74_RS07435 7390047dc088ce749701bdd745184dce 336 SUPERFAMILY SSF53822 58 324 8.78E-37 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS15655 33b2ddc22b95f0cbc5698055e35b9601 311 PRINTS PR00069 Aldo-keto reductase signature 39 63 5.4E-7 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS15655 33b2ddc22b95f0cbc5698055e35b9601 311 PRINTS PR00069 Aldo-keto reductase signature 242 266 5.4E-7 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS15655 33b2ddc22b95f0cbc5698055e35b9601 311 PRINTS PR00069 Aldo-keto reductase signature 103 121 5.4E-7 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS15655 33b2ddc22b95f0cbc5698055e35b9601 311 SUPERFAMILY SSF51430 1 309 1.57E-86 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS15655 33b2ddc22b95f0cbc5698055e35b9601 311 Pfam PF00248 Aldo/keto reductase family 15 295 6.7E-63 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS15655 33b2ddc22b95f0cbc5698055e35b9601 311 Gene3D G3DSA:3.20.20.100 1 309 1.0E-85 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 SMART SM00895 94 219 5.1E-19 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 SUPERFAMILY SSF46785 6 78 1.61E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 SUPERFAMILY SSF48008 90 224 6.8E-25 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.6E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.6E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 SMART SM00345 15 74 9.7E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 Gene3D G3DSA:1.20.120.530 89 224 1.5E-26 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.8E-19 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 Gene3D G3DSA:1.10.10.10 7 78 2.3E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09150 4d23ab9a1647668fe36b8330e4b70c38 234 Pfam PF07729 FCD domain 94 211 3.1E-22 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS00690 4135668b04b5de3bb144ed5fa96267af 272 Pfam PF00005 ABC transporter 47 177 2.1E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00690 4135668b04b5de3bb144ed5fa96267af 272 Gene3D G3DSA:3.40.50.300 40 243 1.0E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00690 4135668b04b5de3bb144ed5fa96267af 272 SUPERFAMILY SSF52540 41 242 3.08E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00690 4135668b04b5de3bb144ed5fa96267af 272 SMART SM00382 56 228 2.8E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04020 3e263fa5e97d76fe7ba2678478666d22 150 Pfam PF14155 Domain of unknown function (DUF4307) 18 126 1.5E-31 T 09-03-2017 IPR025443 Protein of unknown function DUF4307 UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 196 223 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 SUPERFAMILY SSF51735 150 337 3.56E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 Gene3D G3DSA:3.40.50.720 2 184 1.0E-75 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 63 363 1.2E-17 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 Gene3D G3DSA:3.40.50.720 186 344 3.8E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 156 336 1.1E-44 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 SUPERFAMILY SSF52283 3 167 8.72E-59 T 09-03-2017 UA74_RS17135 c9f72ed50d6e587285d2b01dafb278a0 385 Hamap MF_03210 Formate dehydrogenase, mitochondrial. 2 384 53.064 T 09-03-2017 IPR033689 NAD-dependent formate dehydrogenase GO:0008863 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 UA74_RS23950 91c68754892535cb02de637f6fe9b52e 393 Gene3D G3DSA:3.20.20.150 20 380 5.4E-91 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS23950 91c68754892535cb02de637f6fe9b52e 393 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 12 383 1.3E-189 T 09-03-2017 IPR013457 Rhamnose isomerase-related UA74_RS23950 91c68754892535cb02de637f6fe9b52e 393 SUPERFAMILY SSF51658 30 367 1.13E-90 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS23950 91c68754892535cb02de637f6fe9b52e 393 Pfam PF06134 L-rhamnose isomerase (RhaA) 96 341 2.8E-6 T 09-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 UA74_RS23950 91c68754892535cb02de637f6fe9b52e 393 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 110 332 2.0E-7 T 09-03-2017 UA74_RS25985 e9e5e27ae567b7c5097f9843513fb336 484 Gene3D G3DSA:3.40.640.10 149 364 7.3E-43 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS25985 e9e5e27ae567b7c5097f9843513fb336 484 SMART SM00345 30 89 2.2E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS25985 e9e5e27ae567b7c5097f9843513fb336 484 SUPERFAMILY SSF46785 19 93 1.48E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS25985 e9e5e27ae567b7c5097f9843513fb336 484 Pfam PF00155 Aminotransferase class I and II 182 417 1.8E-10 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS25985 e9e5e27ae567b7c5097f9843513fb336 484 Gene3D G3DSA:1.10.10.10 17 90 5.9E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS25985 e9e5e27ae567b7c5097f9843513fb336 484 SUPERFAMILY SSF53383 84 471 3.35E-63 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS25985 e9e5e27ae567b7c5097f9843513fb336 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 89 1.6E-13 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS00255 2df3388eb9cf1fdeda2e4ec94472d39f 330 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 54 321 1.6E-59 T 09-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 UA74_RS00255 2df3388eb9cf1fdeda2e4ec94472d39f 330 Gene3D G3DSA:3.40.190.10 53 155 2.8E-50 T 09-03-2017 UA74_RS00255 2df3388eb9cf1fdeda2e4ec94472d39f 330 Gene3D G3DSA:3.40.190.10 270 326 2.8E-50 T 09-03-2017 UA74_RS00255 2df3388eb9cf1fdeda2e4ec94472d39f 330 Gene3D G3DSA:3.40.190.120 156 263 6.1E-30 T 09-03-2017 UA74_RS00255 2df3388eb9cf1fdeda2e4ec94472d39f 330 SUPERFAMILY SSF53850 54 325 2.14E-59 T 09-03-2017 UA74_RS25220 408d5579f5d8427a181f950dec1ecb50 296 Pfam PF08338 Domain of unknown function (DUF1731) 246 290 4.0E-15 T 09-03-2017 IPR013549 Domain of unknown function DUF1731 UA74_RS25220 408d5579f5d8427a181f950dec1ecb50 296 SUPERFAMILY SSF51735 1 254 3.48E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS25220 408d5579f5d8427a181f950dec1ecb50 296 Gene3D G3DSA:3.40.50.720 1 246 8.8E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS25220 408d5579f5d8427a181f950dec1ecb50 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 119 2.2E-7 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS25220 408d5579f5d8427a181f950dec1ecb50 296 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 289 6.0E-91 T 09-03-2017 IPR010099 Epimerase family protein SDR39U1 UA74_RS10860 4256b19f7b3451453c73ea0cc99c2d24 253 Gene3D G3DSA:3.40.50.300 3 201 4.8E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10860 4256b19f7b3451453c73ea0cc99c2d24 253 Pfam PF02223 Thymidylate kinase 5 194 7.1E-5 T 09-03-2017 UA74_RS10860 4256b19f7b3451453c73ea0cc99c2d24 253 SUPERFAMILY SSF52540 1 201 8.33E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02585 96f2c4297ae16bf756ef0145a14f8e81 262 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 34 181 4.8E-34 T 09-03-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 52 67 1.9E-19 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 32 50 1.9E-19 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 272 294 1.9E-19 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.9E-19 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 111 124 1.9E-19 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 Gene3D G3DSA:3.40.50.1820 6 296 3.8E-54 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.0E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.0E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.0E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 Pfam PF00561 alpha/beta hydrolase fold 27 181 2.2E-23 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22430 0f0e95eeba5ed2bd0d61b03481d2b80e 301 SUPERFAMILY SSF53474 9 296 1.79E-52 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS11495 4284e3658aed2c41934a6712a0169882 353 Pfam PF01595 Domain of unknown function DUF21 8 202 1.1E-41 T 09-03-2017 IPR002550 Domain of unknown function DUF21 UA74_RS11495 4284e3658aed2c41934a6712a0169882 353 SMART SM00116 288 336 59.0 T 09-03-2017 IPR000644 CBS domain UA74_RS11495 4284e3658aed2c41934a6712a0169882 353 SMART SM00116 226 274 0.0071 T 09-03-2017 IPR000644 CBS domain UA74_RS11495 4284e3658aed2c41934a6712a0169882 353 Gene3D G3DSA:3.10.580.10 208 341 2.7E-15 T 09-03-2017 UA74_RS11495 4284e3658aed2c41934a6712a0169882 353 Pfam PF00571 CBS domain 217 271 1.3E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS11495 4284e3658aed2c41934a6712a0169882 353 SUPERFAMILY SSF54631 210 342 9.22E-22 T 09-03-2017 UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 3 54 1.1E-5 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 PIRSF PIRSF006337 1 573 1.8E-221 T 09-03-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 Pfam PF00128 Alpha amylase, catalytic domain 114 193 4.2E-12 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 SUPERFAMILY SSF81296 4 78 1.43E-18 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 Gene3D G3DSA:2.60.40.10 3 77 8.7E-27 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 SMART SM00642 99 456 1.3E-8 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 SUPERFAMILY SSF51445 74 502 7.3E-105 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 540 1.4E-224 T 09-03-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 Pfam PF11941 Domain of unknown function (DUF3459) 488 577 1.1E-15 T 09-03-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 Gene3D G3DSA:3.20.20.80 95 424 4.2E-75 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS21315 0be25f3062a89f6417f5d0111cb02c0e 585 Gene3D G3DSA:3.20.20.80 467 501 4.2E-75 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS24290 e4a64c951038042387af761206161323 330 SUPERFAMILY SSF52283 19 138 1.02E-10 T 09-03-2017 UA74_RS24290 e4a64c951038042387af761206161323 330 Gene3D G3DSA:3.40.50.720 120 292 3.1E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24290 e4a64c951038042387af761206161323 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 126 290 9.0E-44 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS24290 e4a64c951038042387af761206161323 330 Gene3D G3DSA:3.40.50.720 33 119 6.1E-11 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24290 e4a64c951038042387af761206161323 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS24290 e4a64c951038042387af761206161323 330 SUPERFAMILY SSF51735 103 291 5.86E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24290 e4a64c951038042387af761206161323 330 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 201 223 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS10075 61909a9b43c119e378cec1f65af42d58 280 Gene3D G3DSA:1.10.260.40 1 51 4.3E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS10075 61909a9b43c119e378cec1f65af42d58 280 SMART SM00530 1 55 0.0017 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS10075 61909a9b43c119e378cec1f65af42d58 280 SUPERFAMILY SSF47413 1 51 1.75E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS10075 61909a9b43c119e378cec1f65af42d58 280 Pfam PF13560 Helix-turn-helix domain 1 56 3.9E-9 T 09-03-2017 UA74_RS11595 0dccfd8bc194a4e4e11997740a19dbf0 360 Gene3D G3DSA:1.10.8.300 215 332 6.7E-39 T 09-03-2017 UA74_RS11595 0dccfd8bc194a4e4e11997740a19dbf0 360 SUPERFAMILY SSF52540 25 307 9.52E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11595 0dccfd8bc194a4e4e11997740a19dbf0 360 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 56 186 1.4E-58 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_RS11595 0dccfd8bc194a4e4e11997740a19dbf0 360 PIRSF PIRSF002849 3 337 3.1E-132 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted UA74_RS11595 0dccfd8bc194a4e4e11997740a19dbf0 360 Gene3D G3DSA:3.40.50.300 38 202 7.3E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02360 8d8c8549360991952b44dfbc93bc0fc8 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 191 7.8E-34 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS02360 8d8c8549360991952b44dfbc93bc0fc8 210 SMART SM00855 6 158 2.1E-16 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS02360 8d8c8549360991952b44dfbc93bc0fc8 210 SUPERFAMILY SSF53254 6 196 9.69E-36 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS02360 8d8c8549360991952b44dfbc93bc0fc8 210 Gene3D G3DSA:3.40.50.1240 7 191 6.0E-31 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS12560 a1e2819e0d61aacb7d72278f5b492a7e 323 Gene3D G3DSA:3.90.180.10 2 144 7.1E-44 T 09-03-2017 IPR011032 GroES-like UA74_RS12560 a1e2819e0d61aacb7d72278f5b492a7e 323 SMART SM00829 11 321 5.1E-30 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS12560 a1e2819e0d61aacb7d72278f5b492a7e 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 8.2E-9 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS12560 a1e2819e0d61aacb7d72278f5b492a7e 323 Gene3D G3DSA:3.40.50.720 145 252 5.0E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12560 a1e2819e0d61aacb7d72278f5b492a7e 323 Pfam PF00107 Zinc-binding dehydrogenase 150 253 2.1E-27 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS12560 a1e2819e0d61aacb7d72278f5b492a7e 323 SUPERFAMILY SSF50129 2 143 6.54E-38 T 09-03-2017 IPR011032 GroES-like UA74_RS12560 a1e2819e0d61aacb7d72278f5b492a7e 323 SUPERFAMILY SSF51735 112 264 7.05E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03325 ed42ac4e7edee6c2a103ce10e182de36 290 Pfam PF00248 Aldo/keto reductase family 14 285 1.1E-53 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS03325 ed42ac4e7edee6c2a103ce10e182de36 290 SUPERFAMILY SSF51430 3 285 7.2E-69 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS03325 ed42ac4e7edee6c2a103ce10e182de36 290 Gene3D G3DSA:3.20.20.100 2 285 5.8E-71 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 SMART SM00354 4 74 1.7E-25 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 09-03-2017 UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 Pfam PF13377 Periplasmic binding protein-like domain 172 334 5.8E-33 T 09-03-2017 UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 8.2E-14 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 Gene3D G3DSA:3.40.50.2300 57 175 1.3E-39 T 09-03-2017 UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 SUPERFAMILY SSF53822 63 337 3.85E-67 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 Gene3D G3DSA:3.40.50.2300 176 309 1.4E-42 T 09-03-2017 UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 Gene3D G3DSA:1.10.260.40 6 56 1.6E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23960 496dd25cfba806b3bc4bec080f145420 341 SUPERFAMILY SSF47413 5 60 2.53E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS03800 6d8346f72f7e9b06e5d2270c5985495d 470 Pfam PF01882 Protein of unknown function DUF58 222 326 1.3E-16 T 09-03-2017 IPR002881 Domain of unknown function DUF58 UA74_RS24610 c6ecaf70c629991012df4c58a79282c8 246 SUPERFAMILY SSF88697 11 72 3.31E-12 T 09-03-2017 IPR015947 PUA-like domain UA74_RS24610 c6ecaf70c629991012df4c58a79282c8 246 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 8 244 1.4E-41 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS24610 c6ecaf70c629991012df4c58a79282c8 246 PIRSF PIRSF015601 7 246 2.9E-51 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS24610 c6ecaf70c629991012df4c58a79282c8 246 SUPERFAMILY SSF75217 77 246 9.42E-43 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS24610 c6ecaf70c629991012df4c58a79282c8 246 Gene3D G3DSA:3.40.1280.10 14 246 1.5E-69 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS24610 c6ecaf70c629991012df4c58a79282c8 246 Pfam PF04452 RNA methyltransferase 21 240 6.5E-60 T 09-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 UA74_RS18720 fa48a20faf9c294b2e89d557f6edf902 383 SUPERFAMILY SSF69118 14 179 2.75E-26 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_RS18720 fa48a20faf9c294b2e89d557f6edf902 383 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 76 118 2.1E-8 T 09-03-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_RS18720 fa48a20faf9c294b2e89d557f6edf902 383 Pfam PF02627 Carboxymuconolactone decarboxylase family 61 120 3.7E-7 T 09-03-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_RS18720 fa48a20faf9c294b2e89d557f6edf902 383 Gene3D G3DSA:1.20.1290.10 91 181 8.7E-14 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_RS18720 fa48a20faf9c294b2e89d557f6edf902 383 Gene3D G3DSA:1.20.1290.10 318 342 2.5E-9 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_RS18720 fa48a20faf9c294b2e89d557f6edf902 383 Gene3D G3DSA:1.20.1290.10 53 90 2.5E-9 T 09-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_RS02100 9f7d9b13a0f67c1d84249eb832a36fc3 368 Gene3D G3DSA:3.40.50.300 146 296 1.2E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02100 9f7d9b13a0f67c1d84249eb832a36fc3 368 SUPERFAMILY SSF53795 148 236 2.38E-10 T 09-03-2017 UA74_RS15465 59cbf570f85656fcfad1cdf00f0c8a4c 135 Gene3D G3DSA:3.30.70.1060 1 130 5.4E-37 T 09-03-2017 UA74_RS15465 59cbf570f85656fcfad1cdf00f0c8a4c 135 Pfam PF03795 YCII-related domain 15 109 5.6E-11 T 09-03-2017 IPR005545 YCII-related UA74_RS15465 59cbf570f85656fcfad1cdf00f0c8a4c 135 SUPERFAMILY SSF54909 21 124 4.56E-22 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 Pfam PF04408 Helicase associated domain (HA2) 395 453 1.1E-8 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 SMART SM00487 13 194 3.7E-19 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 Pfam PF08482 ATP-dependent helicase C-terminal 723 854 1.6E-52 T 09-03-2017 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 Pfam PF13245 Part of AAA domain 24 81 1.1E-5 T 09-03-2017 UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 SUPERFAMILY SSF52540 26 342 5.19E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 SMART SM00490 234 332 2.3E-14 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 Gene3D G3DSA:3.40.50.300 199 348 6.7E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 SMART SM00847 392 485 2.6E-5 T 09-03-2017 IPR007502 Helicase-associated domain GO:0004386 UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 Gene3D G3DSA:3.40.50.300 15 168 2.4E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05025 26c093e7a43115bb5a781ac3e59408b4 866 Pfam PF00271 Helicase conserved C-terminal domain 217 332 3.4E-10 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS25655 644b54b2133d9412636d6983305ad823 460 TIGRFAM TIGR00836 amt: ammonium transporter 5 413 2.5E-139 T 09-03-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 UA74_RS25655 644b54b2133d9412636d6983305ad823 460 Gene3D G3DSA:1.10.3430.10 1 394 4.9E-135 T 09-03-2017 IPR029020 Ammonium/urea transporter UA74_RS25655 644b54b2133d9412636d6983305ad823 460 Pfam PF00909 Ammonium Transporter Family 7 413 4.3E-126 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 UA74_RS25655 644b54b2133d9412636d6983305ad823 460 ProSitePatterns PS01219 Ammonium transporters signature. 169 194 - T 09-03-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 UA74_RS25655 644b54b2133d9412636d6983305ad823 460 SUPERFAMILY SSF111352 2 394 1.15E-120 T 09-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 UA74_RS15360 d95e875df8759b26df9ad29553fadf51 160 SUPERFAMILY SSF55729 4 149 3.77E-25 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15360 d95e875df8759b26df9ad29553fadf51 160 Gene3D G3DSA:3.40.630.30 10 150 8.6E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15360 d95e875df8759b26df9ad29553fadf51 160 Pfam PF00583 Acetyltransferase (GNAT) family 51 128 3.2E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Gene3D G3DSA:2.102.10.10 36 142 3.0E-32 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 181 371 4.7E-44 T 09-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 SUPERFAMILY SSF50022 12 149 4.58E-43 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Gene3D G3DSA:3.90.380.10 143 368 6.5E-19 T 09-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 51 66 4.4E-21 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 179 201 4.4E-21 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 4.4E-21 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 21 46 4.4E-21 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 72 92 4.4E-21 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 SUPERFAMILY SSF55961 173 372 7.61E-42 T 09-03-2017 UA74_RS06690 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Pfam PF00355 Rieske [2Fe-2S] domain 37 121 4.0E-16 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 Gene3D G3DSA:3.40.50.2300 2 121 8.3E-35 T 09-03-2017 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 SMART SM00421 147 204 7.4E-23 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 2.7E-15 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 Pfam PF00072 Response regulator receiver domain 5 117 4.1E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 SUPERFAMILY SSF46894 136 207 1.63E-18 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 Gene3D G3DSA:1.10.10.10 122 208 1.2E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 SUPERFAMILY SSF52172 3 133 7.26E-32 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.5E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.5E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.5E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS00560 b43db1b688493b186f2a5ec5326ff270 210 SMART SM00448 3 116 3.4E-29 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 Gene3D G3DSA:3.40.50.980 6 155 5.4E-42 T 09-03-2017 UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 Gene3D G3DSA:3.30.300.30 407 524 3.6E-27 T 09-03-2017 UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 32 437 2.4E-113 T 09-03-2017 IPR010071 Amino acid adenylation domain UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 SUPERFAMILY SSF56801 6 521 4.06E-129 T 09-03-2017 UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 Gene3D G3DSA:2.30.38.10 322 395 5.2E-18 T 09-03-2017 UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 Gene3D G3DSA:3.40.50.980 156 311 1.4E-44 T 09-03-2017 UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 512 7.7E-8 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS05235 db22e8a238cde72c873385bbff8ecdc4 527 Pfam PF00501 AMP-binding enzyme 11 413 5.0E-89 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS23355 b997f22a0529379ea62140e073018ee6 45 Pfam PF13586 Transposase DDE domain 2 43 5.3E-8 T 09-03-2017 IPR025668 Transposase DDE domain UA74_RS22840 b351d7c5b017eefe0c3cb8876ae7fbe0 152 Pfam PF12802 MarR family 31 85 3.1E-12 T 09-03-2017 UA74_RS22840 b351d7c5b017eefe0c3cb8876ae7fbe0 152 Gene3D G3DSA:1.10.10.10 4 141 7.5E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22840 b351d7c5b017eefe0c3cb8876ae7fbe0 152 SUPERFAMILY SSF46785 5 141 3.06E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22840 b351d7c5b017eefe0c3cb8876ae7fbe0 152 SMART SM00347 26 126 3.1E-19 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS19215 41ccc72ba47950e6889750041f5b0100 379 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 39 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS19215 41ccc72ba47950e6889750041f5b0100 379 SUPERFAMILY SSF56112 7 262 6.97E-58 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS19215 41ccc72ba47950e6889750041f5b0100 379 SMART SM00220 11 268 9.9E-35 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS19215 41ccc72ba47950e6889750041f5b0100 379 Pfam PF00069 Protein kinase domain 11 260 2.9E-33 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS19215 41ccc72ba47950e6889750041f5b0100 379 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS19215 41ccc72ba47950e6889750041f5b0100 379 Gene3D G3DSA:1.10.510.10 80 258 1.0E-31 T 09-03-2017 UA74_RS19215 41ccc72ba47950e6889750041f5b0100 379 Gene3D G3DSA:3.30.200.20 5 79 9.1E-15 T 09-03-2017 UA74_RS20090 6e2e6f3b850628fc49c6f303da87939c 266 Pfam PF01261 Xylose isomerase-like TIM barrel 29 192 2.0E-24 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS20090 6e2e6f3b850628fc49c6f303da87939c 266 SUPERFAMILY SSF51658 11 262 3.73E-33 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS20090 6e2e6f3b850628fc49c6f303da87939c 266 Gene3D G3DSA:3.20.20.150 1 262 9.4E-32 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS22605 773000a16634866721b7749db96dd881 258 Pfam PF01614 Bacterial transcriptional regulator 123 244 9.7E-30 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS22605 773000a16634866721b7749db96dd881 258 Gene3D G3DSA:3.30.450.40 73 247 1.2E-50 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22605 773000a16634866721b7749db96dd881 258 SMART SM00346 4 95 3.0E-14 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS22605 773000a16634866721b7749db96dd881 258 Gene3D G3DSA:1.10.10.10 4 68 2.7E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22605 773000a16634866721b7749db96dd881 258 SUPERFAMILY SSF55781 73 245 7.19E-45 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22605 773000a16634866721b7749db96dd881 258 Pfam PF09339 IclR helix-turn-helix domain 6 57 8.8E-13 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS22605 773000a16634866721b7749db96dd881 258 SUPERFAMILY SSF46785 4 78 4.5E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 Pfam PF01270 Glycosyl hydrolases family 8 66 420 2.3E-17 T 09-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 SUPERFAMILY SSF48208 63 423 9.07E-73 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 PRINTS PR00735 Glycosyl hydrolase family 8 signature 168 186 1.2E-20 T 09-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 PRINTS PR00735 Glycosyl hydrolase family 8 signature 309 318 1.2E-20 T 09-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 PRINTS PR00735 Glycosyl hydrolase family 8 signature 236 253 1.2E-20 T 09-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 PRINTS PR00735 Glycosyl hydrolase family 8 signature 106 119 1.2E-20 T 09-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 PRINTS PR00735 Glycosyl hydrolase family 8 signature 408 422 1.2E-20 T 09-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 PRINTS PR00735 Glycosyl hydrolase family 8 signature 279 290 1.2E-20 T 09-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_RS10355 c5ecd4fa338a3cbcbfe9b9960a20237e 428 Gene3D G3DSA:1.50.10.10 63 423 9.7E-86 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS05410 14f62fb873112097b33827c745451790 314 Gene3D G3DSA:3.40.50.720 13 240 1.3E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05410 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 3.9E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05410 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 3.9E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05410 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 3.9E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05410 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 3.9E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05410 14f62fb873112097b33827c745451790 314 Pfam PF00106 short chain dehydrogenase 16 217 7.8E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05410 14f62fb873112097b33827c745451790 314 SUPERFAMILY SSF51735 13 221 9.41E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23605 b9c172e8f9e972758d3be156f58bd631 144 Pfam PF12277 Protein of unknown function (DUF3618) 38 69 3.8E-9 T 09-03-2017 IPR022062 Protein of unknown function DUF3618 UA74_RS04995 881443ab03a6ab1fa5b029ff1dc6f656 109 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 1.0E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS04995 881443ab03a6ab1fa5b029ff1dc6f656 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.4E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS04995 881443ab03a6ab1fa5b029ff1dc6f656 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.4E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS04995 881443ab03a6ab1fa5b029ff1dc6f656 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.4E-12 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS04995 881443ab03a6ab1fa5b029ff1dc6f656 109 SMART SM00418 3 81 1.2E-24 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS04995 881443ab03a6ab1fa5b029ff1dc6f656 109 SUPERFAMILY SSF46785 1 97 3.94E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04995 881443ab03a6ab1fa5b029ff1dc6f656 109 Gene3D G3DSA:1.10.10.10 1 101 5.9E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23285 d146d3532fc3b4b7005e70e2f5ee4cb5 213 SUPERFAMILY SSF117987 3 86 2.04E-16 T 09-03-2017 UA74_RS23285 d146d3532fc3b4b7005e70e2f5ee4cb5 213 Pfam PF08798 CRISPR associated protein 4 208 5.1E-45 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS23285 d146d3532fc3b4b7005e70e2f5ee4cb5 213 Gene3D G3DSA:3.30.70.1210 96 208 1.2E-19 T 09-03-2017 UA74_RS23285 d146d3532fc3b4b7005e70e2f5ee4cb5 213 SMART SM01101 3 208 5.0E-45 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS23285 d146d3532fc3b4b7005e70e2f5ee4cb5 213 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 26 208 1.1E-18 T 09-03-2017 IPR010179 CRISPR-associated protein Cse3 UA74_RS23285 d146d3532fc3b4b7005e70e2f5ee4cb5 213 Gene3D G3DSA:3.30.70.1200 3 84 3.8E-19 T 09-03-2017 UA74_RS23285 d146d3532fc3b4b7005e70e2f5ee4cb5 213 SUPERFAMILY SSF117987 94 208 3.4E-22 T 09-03-2017 UA74_RS22290 005c46b8d4e359020953d89c9fa7e9b6 217 Pfam PF13649 Methyltransferase domain 39 128 2.9E-14 T 09-03-2017 UA74_RS22290 005c46b8d4e359020953d89c9fa7e9b6 217 Gene3D G3DSA:3.40.50.150 19 216 7.3E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS22290 005c46b8d4e359020953d89c9fa7e9b6 217 SUPERFAMILY SSF53335 3 208 2.43E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00330 a557f1bcb87d5869e071a9fcb178a306 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 56 8.6E-10 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS00330 a557f1bcb87d5869e071a9fcb178a306 83 SUPERFAMILY SSF143120 1 81 4.58E-24 T 09-03-2017 UA74_RS00330 a557f1bcb87d5869e071a9fcb178a306 83 Gene3D G3DSA:3.40.1620.10 1 51 6.1E-12 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS00330 a557f1bcb87d5869e071a9fcb178a306 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 73 3.1E-21 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 49 3.9E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 33 3.9E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 SMART SM00345 1 59 7.0E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 Pfam PF07729 FCD domain 85 205 4.4E-26 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 SUPERFAMILY SSF46785 2 63 2.01E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 Gene3D G3DSA:1.20.120.530 81 215 4.4E-29 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 Gene3D G3DSA:1.10.10.10 2 69 3.6E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 SUPERFAMILY SSF48008 82 213 4.97E-27 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 SMART SM00895 85 207 5.2E-21 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS18300 a9bc1d94eeab397c9ccfae3ad3206591 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 59 9.0E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 SUPERFAMILY SSF48264 26 410 4.71E-97 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 199 221 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 350 359 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 97 108 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 301 328 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 283 294 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 329 344 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 161 176 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 359 370 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00359 B-class P450 signature 144 160 1.2E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 Pfam PF00067 Cytochrome P450 35 380 2.1E-34 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00385 P450 superfamily signature 248 265 6.7E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00385 P450 superfamily signature 359 370 6.7E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00385 P450 superfamily signature 283 294 6.7E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 PRINTS PR00385 P450 superfamily signature 350 359 6.7E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12790 4fa2298fe5059066c1f74b9d26bdc1b6 411 Gene3D G3DSA:1.10.630.10 18 410 1.8E-122 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS26660 174f5cef3f936ef8460c815f0d355765 261 SUPERFAMILY SSF143081 2 241 5.89E-63 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) UA74_RS26660 174f5cef3f936ef8460c815f0d355765 261 Gene3D G3DSA:3.90.1680.10 1 242 3.3E-67 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) UA74_RS26660 174f5cef3f936ef8460c815f0d355765 261 Pfam PF02586 SOS response associated peptidase (SRAP) 1 232 1.1E-61 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 SUPERFAMILY SSF51430 7 268 4.71E-95 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.4E-49 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 196 220 4.4E-49 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 159 188 4.4E-49 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 93 111 4.4E-49 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 125 142 4.4E-49 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 PIRSF PIRSF000097 1 272 3.8E-88 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 Pfam PF00248 Aldo/keto reductase family 24 260 6.4E-48 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 Gene3D G3DSA:3.20.20.100 7 270 8.0E-106 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS21235 988804842d49a455dafdf69d89d9b193 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS04670 a7eb53adb3d6edaee5dbbec3a62b078a 281 Gene3D G3DSA:1.10.3720.10 12 268 8.7E-65 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04670 a7eb53adb3d6edaee5dbbec3a62b078a 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 274 4.2E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04670 a7eb53adb3d6edaee5dbbec3a62b078a 281 SUPERFAMILY SSF161098 11 281 7.01E-74 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23205 b595d4fc024269721ca9839a4784d792 187 PIRSF PIRSF018427 1 184 8.1E-51 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_RS23205 b595d4fc024269721ca9839a4784d792 187 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 14 173 1.0E-43 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_RS23205 b595d4fc024269721ca9839a4784d792 187 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 12 185 34.208 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_RS23205 b595d4fc024269721ca9839a4784d792 187 SUPERFAMILY SSF55811 12 177 6.63E-45 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS23205 b595d4fc024269721ca9839a4784d792 187 Pfam PF00293 NUDIX domain 39 155 4.6E-20 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS23205 b595d4fc024269721ca9839a4784d792 187 Gene3D G3DSA:3.90.79.10 39 179 3.6E-39 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS17385 ab65ba0525d33758075e9293cbc3b60e 471 SUPERFAMILY SSF51338 16 77 2.53E-22 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17385 ab65ba0525d33758075e9293cbc3b60e 471 SUPERFAMILY SSF51338 382 455 2.53E-22 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17385 ab65ba0525d33758075e9293cbc3b60e 471 SUPERFAMILY SSF51556 77 383 4.66E-46 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS17385 ab65ba0525d33758075e9293cbc3b60e 471 Gene3D G3DSA:3.20.20.140 80 390 2.4E-47 T 09-03-2017 UA74_RS17385 ab65ba0525d33758075e9293cbc3b60e 471 Pfam PF01979 Amidohydrolase family 74 428 3.2E-26 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS17385 ab65ba0525d33758075e9293cbc3b60e 471 Gene3D G3DSA:2.30.40.10 391 432 1.5E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17385 ab65ba0525d33758075e9293cbc3b60e 471 Gene3D G3DSA:2.30.40.10 13 79 1.5E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 Gene3D G3DSA:3.20.20.210 12 394 1.5E-129 T 09-03-2017 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 15 763 0.0 T 09-03-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 436 758 1.5E-145 T 09-03-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 SUPERFAMILY SSF51726 414 763 7.59E-112 T 09-03-2017 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 Gene3D G3DSA:3.20.20.210 399 764 2.8E-122 T 09-03-2017 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 PIRSF PIRSF000382 9 766 0.0 T 09-03-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 763 33.845 T 09-03-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 321 3.6E-107 T 09-03-2017 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS11400 f6afd623acb6b752d4bb36a06d851f2b 766 SUPERFAMILY SSF51726 12 394 1.05E-90 T 09-03-2017 UA74_RS21310 e217e23e5ec0e935ae4aa85d872a3ebd 147 Pfam PF07681 DoxX 31 105 1.4E-4 T 09-03-2017 IPR032808 DoxX family UA74_RS26880 08e9ec88778c8a5d611ced755fc7d7d3 834 SUPERFAMILY SSF53448 7 250 1.5E-51 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS26880 08e9ec88778c8a5d611ced755fc7d7d3 834 SUPERFAMILY SSF53756 378 768 1.51E-23 T 09-03-2017 UA74_RS26880 08e9ec88778c8a5d611ced755fc7d7d3 834 Pfam PF13692 Glycosyl transferases group 1 581 737 2.6E-10 T 09-03-2017 UA74_RS26880 08e9ec88778c8a5d611ced755fc7d7d3 834 Pfam PF13641 Glycosyltransferase like family 2 8 227 3.1E-17 T 09-03-2017 UA74_RS26880 08e9ec88778c8a5d611ced755fc7d7d3 834 Gene3D G3DSA:3.90.550.10 8 253 2.9E-48 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 Pfam PF01386 Ribosomal L25p family 6 93 8.4E-24 T 09-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 177 2.3E-47 T 09-03-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 Gene3D G3DSA:2.40.240.10 3 96 5.1E-28 T 09-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 179 6.3E-17 T 09-03-2017 IPR020057 Ribosomal protein L25, beta domain UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 Gene3D G3DSA:2.170.120.20 98 187 2.4E-19 T 09-03-2017 IPR020057 Ribosomal protein L25, beta domain UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 SUPERFAMILY SSF50715 11 179 1.69E-47 T 09-03-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 181 24.718 T 09-03-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_RS03630 94106ccbe62499e6fa3062a6d1cd7201 206 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 92 6.0E-19 T 09-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_RS01030 5bcf7e4cb40073b3ed93b211cf694628 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 310 3.6E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01030 5bcf7e4cb40073b3ed93b211cf694628 311 Gene3D G3DSA:1.10.3720.10 101 307 5.9E-27 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01030 5bcf7e4cb40073b3ed93b211cf694628 311 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 83 8.2E-13 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_RS01030 5bcf7e4cb40073b3ed93b211cf694628 311 SUPERFAMILY SSF161098 102 291 1.19E-27 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS05690 402009abb129c7863d0aa47132cbd21c 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 9.1E-129 T 09-03-2017 IPR002823 Protein of unknown function DUF112, transmembrane UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 466 8.0E-26 T 09-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 SUPERFAMILY SSF52935 322 468 2.75E-36 T 09-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 SUPERFAMILY SSF51621 166 338 8.03E-95 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 SUPERFAMILY SSF51621 2 76 8.03E-95 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 Gene3D G3DSA:3.40.1380.20 325 466 7.0E-39 T 09-03-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 2.6E-170 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 PRINTS PR01050 Pyruvate kinase family signature 216 242 7.4E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 PRINTS PR01050 Pyruvate kinase family signature 243 267 7.4E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 PRINTS PR01050 Pyruvate kinase family signature 312 328 7.4E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 PRINTS PR01050 Pyruvate kinase family signature 185 199 7.4E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 PRINTS PR01050 Pyruvate kinase family signature 60 76 7.4E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 PRINTS PR01050 Pyruvate kinase family signature 268 292 7.4E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 PRINTS PR01050 Pyruvate kinase family signature 293 311 7.4E-66 T 09-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 Gene3D G3DSA:2.40.33.10 74 167 3.3E-29 T 09-03-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 Gene3D G3DSA:3.20.20.60 3 73 4.5E-101 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 Gene3D G3DSA:3.20.20.60 168 324 4.5E-101 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 SUPERFAMILY SSF50800 71 165 8.02E-26 T 09-03-2017 IPR011037 Pyruvate kinase-like, insert domain UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 Pfam PF00224 Pyruvate kinase, barrel domain 3 337 2.1E-120 T 09-03-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS21380 bfffa8e316f4fe633ce8768a985b9c6c 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 214 226 - T 09-03-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_RS28350 a0778050bdbe74a7978157302355247c 948 Gene3D G3DSA:3.40.50.300 391 594 9.7E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28350 a0778050bdbe74a7978157302355247c 948 SUPERFAMILY SSF52540 378 597 1.57E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28350 a0778050bdbe74a7978157302355247c 948 Pfam PF01580 FtsK/SpoIIIE family 392 594 1.0E-20 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_RS04800 7ad55cb353d1a4221ca56a37ab856fde 109 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 7 80 4.1E-15 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS04800 7ad55cb353d1a4221ca56a37ab856fde 109 Gene3D G3DSA:1.10.10.10 4 83 2.2E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04800 7ad55cb353d1a4221ca56a37ab856fde 109 SUPERFAMILY SSF46767 5 80 2.35E-14 T 09-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_RS04005 7e5c1e67660b3369f2e25255125ba7bc 398 Gene3D G3DSA:3.10.180.10 203 398 2.1E-77 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS04005 7e5c1e67660b3369f2e25255125ba7bc 398 Gene3D G3DSA:3.10.180.10 31 202 4.6E-45 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS04005 7e5c1e67660b3369f2e25255125ba7bc 398 SUPERFAMILY SSF54593 30 385 5.65E-89 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS04005 7e5c1e67660b3369f2e25255125ba7bc 398 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 38 398 1.7E-126 T 09-03-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_RS04005 7e5c1e67660b3369f2e25255125ba7bc 398 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 40 149 8.3E-7 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS04005 7e5c1e67660b3369f2e25255125ba7bc 398 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 209 352 8.3E-15 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS04005 7e5c1e67660b3369f2e25255125ba7bc 398 PIRSF PIRSF009283 25 398 5.5E-130 T 09-03-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_RS23475 82062f9c017d7921f9bd7beb7196ad92 280 Gene3D G3DSA:1.10.357.10 27 276 2.9E-53 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS23475 82062f9c017d7921f9bd7beb7196ad92 280 SUPERFAMILY SSF48498 107 273 1.56E-20 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS23475 82062f9c017d7921f9bd7beb7196ad92 280 SUPERFAMILY SSF46689 31 94 2.36E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS23475 82062f9c017d7921f9bd7beb7196ad92 280 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 101 206 1.8E-12 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS23475 82062f9c017d7921f9bd7beb7196ad92 280 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 5.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 Gene3D G3DSA:3.50.50.60 268 347 1.3E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 Gene3D G3DSA:3.50.50.60 8 175 1.3E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 Pfam PF01494 FAD binding domain 10 343 4.7E-27 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 SUPERFAMILY SSF51905 10 168 1.09E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 SUPERFAMILY SSF51905 268 371 1.09E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.5E-19 T 09-03-2017 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.5E-19 T 09-03-2017 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 2.5E-19 T 09-03-2017 UA74_RS10930 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 2.5E-19 T 09-03-2017 UA74_RS25170 f04e00ef8cd5eaf2023b55bcb3cbb773 357 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 20 351 4.4E-128 T 09-03-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS25170 f04e00ef8cd5eaf2023b55bcb3cbb773 357 Pfam PF02277 Phosphoribosyltransferase 16 351 8.6E-137 T 09-03-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS25170 f04e00ef8cd5eaf2023b55bcb3cbb773 357 Gene3D G3DSA:3.40.50.10210 79 333 1.1E-107 T 09-03-2017 UA74_RS25170 f04e00ef8cd5eaf2023b55bcb3cbb773 357 SUPERFAMILY SSF52733 12 352 7.46E-113 T 09-03-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS25170 f04e00ef8cd5eaf2023b55bcb3cbb773 357 Gene3D G3DSA:1.10.1610.10 10 78 9.4E-34 T 09-03-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS25170 f04e00ef8cd5eaf2023b55bcb3cbb773 357 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 18 353 36.88 T 09-03-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 SUPERFAMILY SSF48498 96 247 8.89E-23 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 Gene3D G3DSA:1.10.357.10 22 247 9.6E-50 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 9.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 9.1E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 245 9.1E-12 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 78 8.8E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 SUPERFAMILY SSF46689 23 84 9.98E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22580 22a60b4690ed676d9a6a9641cfac547a 342 Gene3D G3DSA:3.40.50.300 51 278 2.5E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22580 22a60b4690ed676d9a6a9641cfac547a 342 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS22580 22a60b4690ed676d9a6a9641cfac547a 342 SUPERFAMILY SSF52540 50 276 4.73E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22580 22a60b4690ed676d9a6a9641cfac547a 342 SMART SM00382 65 253 7.5E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22580 22a60b4690ed676d9a6a9641cfac547a 342 Pfam PF00005 ABC transporter 56 204 1.2E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00460 b88dfe8b1aed345e72330e098af9628e 269 Pfam PF14011 EspG family 10 259 8.3E-48 T 09-03-2017 IPR025734 EspG family UA74_RS04795 a504041dc4c90e6af98b3fb04a83c44f 262 PIRSF PIRSF017393 2 262 3.6E-83 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS04795 a504041dc4c90e6af98b3fb04a83c44f 262 Pfam PF04672 S-adenosyl methyltransferase 10 261 2.2E-79 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS04795 a504041dc4c90e6af98b3fb04a83c44f 262 SUPERFAMILY SSF53335 7 242 3.07E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04795 a504041dc4c90e6af98b3fb04a83c44f 262 Gene3D G3DSA:3.40.50.150 5 261 1.3E-92 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15675 039221f0d184524f7313f7b95411d11e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 3.5E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS15675 039221f0d184524f7313f7b95411d11e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 3.5E-7 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS15675 039221f0d184524f7313f7b95411d11e 120 SMART SM00418 25 103 2.2E-11 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS15675 039221f0d184524f7313f7b95411d11e 120 Pfam PF12840 Helix-turn-helix domain 25 79 7.8E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15675 039221f0d184524f7313f7b95411d11e 120 Gene3D G3DSA:1.10.10.10 21 102 3.1E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15675 039221f0d184524f7313f7b95411d11e 120 SUPERFAMILY SSF46785 11 102 3.18E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 Gene3D G3DSA:3.30.420.40 176 204 1.1E-15 T 09-03-2017 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 Gene3D G3DSA:3.30.420.40 294 332 1.1E-15 T 09-03-2017 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 312 326 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 Gene3D G3DSA:3.30.420.40 3 175 4.5E-23 T 09-03-2017 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 SUPERFAMILY SSF53067 166 351 2.8E-32 T 09-03-2017 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 Gene3D G3DSA:3.90.640.10 205 286 4.8E-7 T 09-03-2017 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 30 42 2.2E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 177 187 2.2E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 2 15 2.2E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 309 325 2.2E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 Pfam PF00012 Hsp70 protein 88 350 3.1E-30 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS24735 028d34ef423a3607025b73f37706eebd 656 SUPERFAMILY SSF53067 3 156 2.49E-22 T 09-03-2017 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 SUPERFAMILY SSF161093 270 440 3.27E-48 T 09-03-2017 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 Gene3D G3DSA:1.10.357.20 269 441 6.8E-57 T 09-03-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 SMART SM00924 24 127 1.0E-24 T 09-03-2017 IPR006668 Magnesium transporter, MgtE intracellular domain UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 SUPERFAMILY SSF158791 3 124 5.1E-24 T 09-03-2017 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 Gene3D G3DSA:1.25.60.10 3 120 5.9E-19 T 09-03-2017 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 Gene3D G3DSA:3.10.580.10 121 255 1.1E-23 T 09-03-2017 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 SMART SM00116 134 187 3.0 T 09-03-2017 IPR000644 CBS domain UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 SMART SM00116 198 246 8.5E-6 T 09-03-2017 IPR000644 CBS domain UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF03448 MgtE intracellular N domain 26 124 2.4E-20 T 09-03-2017 IPR006668 Magnesium transporter, MgtE intracellular domain UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF00571 CBS domain 192 246 3.7E-6 T 09-03-2017 IPR000644 CBS domain UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF00571 CBS domain 127 183 1.3E-6 T 09-03-2017 IPR000644 CBS domain UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 SUPERFAMILY SSF54631 126 264 1.89E-30 T 09-03-2017 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 TIGRFAM TIGR00400 mgtE: magnesium transporter 5 441 6.9E-119 T 09-03-2017 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 UA74_RS25515 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF01769 Divalent cation transporter 313 434 4.0E-30 T 09-03-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 UA74_RS03995 7b5d2addd5128ce5161ab5f45825d3db 521 Pfam PF06259 Alpha/beta hydrolase 300 464 4.9E-30 T 09-03-2017 IPR010427 Protein of unknown function DUF1023 UA74_RS03995 7b5d2addd5128ce5161ab5f45825d3db 521 SUPERFAMILY SSF140453 11 95 1.05E-5 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS03995 7b5d2addd5128ce5161ab5f45825d3db 521 Gene3D G3DSA:1.10.287.1060 10 75 3.0E-5 T 09-03-2017 UA74_RS03995 7b5d2addd5128ce5161ab5f45825d3db 521 SUPERFAMILY SSF53474 358 461 5.28E-5 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.2E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.2E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 7.2E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 7.2E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.2E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.2E-27 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.3E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.3E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.3E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 193 0.0038 T 09-03-2017 UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 Pfam PF00106 short chain dehydrogenase 7 199 5.3E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 SUPERFAMILY SSF51735 7 248 1.83E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00270 b1720da2f80b720dcc0f58d419bea227 252 Gene3D G3DSA:3.40.50.720 2 248 7.0E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05175 a1079788a8bba4204c5595e79e5fce30 167 Pfam PF00589 Phage integrase family 106 146 2.7E-7 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS05175 a1079788a8bba4204c5595e79e5fce30 167 Gene3D G3DSA:1.10.443.10 105 160 1.3E-9 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS05175 a1079788a8bba4204c5595e79e5fce30 167 SUPERFAMILY SSF56349 98 158 6.18E-10 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS14020 e99f73e9c96c7056a674d090afa8bbd4 167 SUPERFAMILY SSF55846 2 158 8.24E-35 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS14020 e99f73e9c96c7056a674d090afa8bbd4 167 SMART SM00644 12 145 4.0E-5 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS14020 e99f73e9c96c7056a674d090afa8bbd4 167 Gene3D G3DSA:3.40.80.10 2 160 1.7E-33 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS14020 e99f73e9c96c7056a674d090afa8bbd4 167 SMART SM00701 1 137 1.3E-9 T 09-03-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 UA74_RS14020 e99f73e9c96c7056a674d090afa8bbd4 167 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 25 145 2.5E-11 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS09815 5484ac1ef4088f9bbcd99f769d860c4f 198 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 37 194 15.094 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS09815 5484ac1ef4088f9bbcd99f769d860c4f 198 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 169 185 1.4E-16 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS09815 5484ac1ef4088f9bbcd99f769d860c4f 198 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 84 92 1.4E-16 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS09815 5484ac1ef4088f9bbcd99f769d860c4f 198 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 141 1.4E-16 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS09815 5484ac1ef4088f9bbcd99f769d860c4f 198 ProSitePatterns PS00855 Signal peptidases II signature. 129 141 - T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS09815 5484ac1ef4088f9bbcd99f769d860c4f 198 Pfam PF01252 Signal peptidase (SPase) II 46 187 7.7E-29 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS09815 5484ac1ef4088f9bbcd99f769d860c4f 198 TIGRFAM TIGR00077 lspA: signal peptidase II 38 190 1.6E-26 T 09-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 Gene3D G3DSA:3.40.50.300 668 729 3.3E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 Gene3D G3DSA:3.40.50.300 590 651 6.3E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 Pfam PF13538 UvrD-like helicase C-terminal domain 668 717 4.1E-8 T 09-03-2017 IPR027785 UvrD-like helicase C-terminal domain UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 Pfam PF13245 Part of AAA domain 183 244 2.8E-15 T 09-03-2017 UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 Gene3D G3DSA:3.40.50.300 491 589 4.3E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 Gene3D G3DSA:3.40.50.300 166 274 4.3E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 SUPERFAMILY SSF52540 509 721 7.31E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 SUPERFAMILY SSF52540 383 435 7.31E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17295 1014de1d003bf1d9953b90052c2f9756 739 SUPERFAMILY SSF52540 165 244 7.31E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 224 2.7E-109 T 09-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 09-03-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 SUPERFAMILY SSF52313 6 228 1.83E-93 T 09-03-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Gene3D G3DSA:1.10.287.610 100 152 3.8E-23 T 09-03-2017 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 231 42.523 T 09-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Gene3D G3DSA:3.40.50.10490 158 235 9.1E-68 T 09-03-2017 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Gene3D G3DSA:3.40.50.10490 23 99 9.1E-68 T 09-03-2017 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 196 210 6.6E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.6E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.6E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.6E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 175 186 6.6E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 158 175 6.6E-39 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS09035 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Pfam PF00318 Ribosomal protein S2 9 224 1.3E-96 T 09-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS29420 067d9ff1b2c9091625d4fc5573fa93b3 285 Gene3D G3DSA:3.20.20.80 79 284 2.8E-72 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS29420 067d9ff1b2c9091625d4fc5573fa93b3 285 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 84 117 - T 09-03-2017 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 UA74_RS29420 067d9ff1b2c9091625d4fc5573fa93b3 285 SUPERFAMILY SSF51445 78 284 2.95E-63 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS29420 067d9ff1b2c9091625d4fc5573fa93b3 285 SMART SM00641 80 189 1.2E-44 T 09-03-2017 IPR018077 Glycoside hydrolase, family 25 subgroup UA74_RS29420 067d9ff1b2c9091625d4fc5573fa93b3 285 Pfam PF01183 Glycosyl hydrolases family 25 83 267 2.3E-49 T 09-03-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 UA74_RS10675 79c3b83c0200e320da1368ba98787f6f 402 SUPERFAMILY SSF53822 66 396 2.76E-66 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS10675 79c3b83c0200e320da1368ba98787f6f 402 Gene3D G3DSA:3.40.50.2300 66 257 2.2E-39 T 09-03-2017 UA74_RS10675 79c3b83c0200e320da1368ba98787f6f 402 Pfam PF13458 Periplasmic binding protein 66 393 4.9E-43 T 09-03-2017 IPR028081 Leucine-binding protein domain UA74_RS20725 a52f2e03c6994fcc290bc3a58c0c0af4 155 SUPERFAMILY SSF55811 7 135 2.98E-21 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS20725 a52f2e03c6994fcc290bc3a58c0c0af4 155 PRINTS PR00502 NUDIX hydrolase family signature 53 68 2.1E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS20725 a52f2e03c6994fcc290bc3a58c0c0af4 155 PRINTS PR00502 NUDIX hydrolase family signature 38 52 2.1E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS20725 a52f2e03c6994fcc290bc3a58c0c0af4 155 Gene3D G3DSA:3.90.79.10 8 140 1.2E-20 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS20725 a52f2e03c6994fcc290bc3a58c0c0af4 155 Pfam PF00293 NUDIX domain 10 126 2.3E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS11490 cdc2a2ed88e6167ad7ad10ae3c333153 360 SUPERFAMILY SSF53850 17 316 2.71E-6 T 09-03-2017 UA74_RS11490 cdc2a2ed88e6167ad7ad10ae3c333153 360 Pfam PF13531 Bacterial extracellular solute-binding protein 20 316 3.0E-22 T 09-03-2017 UA74_RS01350 d4d45a1bc02f4d90d8185e43879f5745 277 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 17 215 1.5E-63 T 09-03-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial UA74_RS01350 d4d45a1bc02f4d90d8185e43879f5745 277 Gene3D G3DSA:3.40.50.1000 88 235 7.9E-46 T 09-03-2017 IPR023214 HAD-like domain UA74_RS01350 d4d45a1bc02f4d90d8185e43879f5745 277 Pfam PF12710 haloacid dehalogenase-like hydrolase 18 202 1.4E-32 T 09-03-2017 UA74_RS01350 d4d45a1bc02f4d90d8185e43879f5745 277 SUPERFAMILY SSF56784 15 227 2.34E-29 T 09-03-2017 IPR023214 HAD-like domain UA74_RS01350 d4d45a1bc02f4d90d8185e43879f5745 277 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 17 204 1.9E-21 T 09-03-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 SUPERFAMILY SSF48264 12 399 1.03E-97 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 237 254 5.7E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 339 348 5.7E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 272 283 5.7E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 348 359 5.7E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 94 105 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 195 217 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 158 173 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 141 157 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 348 359 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 339 348 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 272 283 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 318 333 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 290 317 1.7E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 Pfam PF00067 Cytochrome P450 185 369 3.4E-30 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17285 69a79b8e817315574a6cdf633eed216a 399 Gene3D G3DSA:1.10.630.10 10 399 3.2E-120 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS11025 4303fdf1e2c620d1c2d0a93d207fed16 472 SUPERFAMILY SSF103473 10 205 2.09E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS11025 4303fdf1e2c620d1c2d0a93d207fed16 472 SUPERFAMILY SSF103473 255 464 2.09E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS11025 4303fdf1e2c620d1c2d0a93d207fed16 472 Gene3D G3DSA:1.20.1250.20 270 466 4.1E-19 T 09-03-2017 UA74_RS11025 4303fdf1e2c620d1c2d0a93d207fed16 472 Pfam PF07690 Major Facilitator Superfamily 26 417 1.6E-46 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS11025 4303fdf1e2c620d1c2d0a93d207fed16 472 Gene3D G3DSA:1.20.1250.20 22 202 2.4E-24 T 09-03-2017 UA74_RS23455 de400368ead7a901fa5f1063ebb6136c 133 Gene3D G3DSA:1.10.10.10 6 131 4.4E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23455 de400368ead7a901fa5f1063ebb6136c 133 SMART SM00347 21 120 2.0E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS23455 de400368ead7a901fa5f1063ebb6136c 133 SUPERFAMILY SSF46785 10 131 1.88E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23455 de400368ead7a901fa5f1063ebb6136c 133 Pfam PF13463 Winged helix DNA-binding domain 37 93 5.6E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 SUPERFAMILY SSF46785 7 139 8.49E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.1E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 4.1E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 4.1E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 4.1E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 Gene3D G3DSA:1.10.10.10 8 137 5.1E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 SMART SM00347 28 127 3.1E-16 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05450 357cb77a7de5a85b18ddf2c3bd266998 145 Pfam PF01047 MarR family 40 91 8.6E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05415 746083a632f3b0f2ed95b1aebebf0eb6 279 SMART SM00530 10 82 2.0E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS05415 746083a632f3b0f2ed95b1aebebf0eb6 279 Gene3D G3DSA:1.10.260.40 5 81 1.4E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05415 746083a632f3b0f2ed95b1aebebf0eb6 279 Pfam PF13560 Helix-turn-helix domain 7 85 1.5E-16 T 09-03-2017 UA74_RS05415 746083a632f3b0f2ed95b1aebebf0eb6 279 SUPERFAMILY SSF47413 30 81 5.0E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 SUPERFAMILY SSF49319 191 307 6.38E-8 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 SUPERFAMILY SSF49319 132 184 4.41E-9 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 SUPERFAMILY SSF49319 50 104 4.41E-9 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 Gene3D G3DSA:2.60.40.230 192 307 9.1E-18 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 Gene3D G3DSA:2.60.40.230 50 184 6.2E-17 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 Gene3D G3DSA:2.60.40.230 313 424 1.0E-22 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 Gene3D G3DSA:2.60.40.230 444 569 3.2E-19 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 SUPERFAMILY SSF49319 445 569 1.03E-11 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 71 - T 09-03-2017 IPR010916 TonB box, conserved site UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 SUPERFAMILY SSF49319 313 424 1.31E-16 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29920 a4f40dc01236b45c90ee59975150b848 667 Pfam PF00960 Neocarzinostatin family 315 408 2.2E-7 T 09-03-2017 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 UA74_RS15250 cb97a785db623537358445f5d64ac9d0 522 SMART SM00729 180 386 3.6E-6 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS15250 cb97a785db623537358445f5d64ac9d0 522 Gene3D G3DSA:3.80.30.20 183 354 2.0E-25 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe UA74_RS15250 cb97a785db623537358445f5d64ac9d0 522 SUPERFAMILY SSF102114 153 338 6.15E-21 T 09-03-2017 UA74_RS15250 cb97a785db623537358445f5d64ac9d0 522 Pfam PF02310 B12 binding domain 15 125 5.1E-17 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS15250 cb97a785db623537358445f5d64ac9d0 522 SUPERFAMILY SSF52242 18 119 3.45E-5 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS15250 cb97a785db623537358445f5d64ac9d0 522 Pfam PF04055 Radical SAM superfamily 185 329 2.9E-9 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.4E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.4E-5 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.3E-17 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 SUPERFAMILY SSF53822 62 341 1.04E-63 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 Gene3D G3DSA:1.10.260.40 3 62 2.0E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 Gene3D G3DSA:3.40.50.2300 63 182 2.6E-39 T 09-03-2017 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 09-03-2017 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 SMART SM00354 2 72 8.8E-24 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 Pfam PF13377 Periplasmic binding protein-like domain 178 338 6.5E-32 T 09-03-2017 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 Gene3D G3DSA:3.40.50.2300 183 314 2.4E-48 T 09-03-2017 UA74_RS23665 70080cfa6324b5eca057a14fef933d0a 351 SUPERFAMILY SSF47413 3 56 6.66E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28620 6fbd608306b8d5268f41bd5937320ff4 203 SUPERFAMILY SSF52540 21 194 2.85E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28620 6fbd608306b8d5268f41bd5937320ff4 203 Gene3D G3DSA:3.40.50.300 16 195 1.2E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28620 6fbd608306b8d5268f41bd5937320ff4 203 Pfam PF03029 Conserved hypothetical ATP binding protein 26 194 1.1E-27 T 09-03-2017 IPR004130 GPN-loop GTPase UA74_RS27765 f022aae5f1e582625d511180b2238d95 66 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 3.2E-26 T 09-03-2017 IPR015035 Domain of unknown function DUF1918 UA74_RS27765 f022aae5f1e582625d511180b2238d95 66 SUPERFAMILY SSF50118 1 61 8.5E-22 T 09-03-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor UA74_RS10950 52cc6d5a166bccfe109b193b0f966d6e 510 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 482 1.7E-84 T 09-03-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 UA74_RS10950 52cc6d5a166bccfe109b193b0f966d6e 510 SUPERFAMILY SSF103473 13 202 7.19E-18 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS10950 52cc6d5a166bccfe109b193b0f966d6e 510 Pfam PF00854 POT family 94 457 5.4E-33 T 09-03-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 UA74_RS10950 52cc6d5a166bccfe109b193b0f966d6e 510 SUPERFAMILY SSF103473 200 483 4.19E-13 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS10950 52cc6d5a166bccfe109b193b0f966d6e 510 Gene3D G3DSA:1.20.1250.20 20 199 5.0E-14 T 09-03-2017 UA74_RS10950 52cc6d5a166bccfe109b193b0f966d6e 510 Gene3D G3DSA:1.20.1250.20 287 481 3.3E-13 T 09-03-2017 UA74_RS27110 b370acf331b4c3a45eed608095b9eb9c 558 Gene3D G3DSA:1.10.3720.10 4 267 4.0E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS27110 b370acf331b4c3a45eed608095b9eb9c 558 Gene3D G3DSA:1.10.3720.10 291 546 6.9E-34 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS27110 b370acf331b4c3a45eed608095b9eb9c 558 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 371 547 3.1E-9 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS27110 b370acf331b4c3a45eed608095b9eb9c 558 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 272 5.7E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS27110 b370acf331b4c3a45eed608095b9eb9c 558 SUPERFAMILY SSF161098 291 547 1.03E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS27110 b370acf331b4c3a45eed608095b9eb9c 558 SUPERFAMILY SSF161098 4 272 3.53E-48 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23250 29b455bdfc264d4b7b1211d36ac9c1d2 270 SUPERFAMILY SSF53335 13 252 2.15E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23250 29b455bdfc264d4b7b1211d36ac9c1d2 270 PIRSF PIRSF017393 1 269 7.1E-86 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS23250 29b455bdfc264d4b7b1211d36ac9c1d2 270 Pfam PF04672 S-adenosyl methyltransferase 10 268 1.1E-79 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS23250 29b455bdfc264d4b7b1211d36ac9c1d2 270 Gene3D G3DSA:3.40.50.150 1 267 1.7E-92 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14720 5d63fbdf9945414d30f60ee832f97d99 277 Gene3D G3DSA:1.10.260.40 4 80 1.2E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS14720 5d63fbdf9945414d30f60ee832f97d99 277 SUPERFAMILY SSF47413 28 80 4.74E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS14720 5d63fbdf9945414d30f60ee832f97d99 277 SMART SM00530 9 81 4.9E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS14720 5d63fbdf9945414d30f60ee832f97d99 277 Pfam PF13560 Helix-turn-helix domain 5 83 9.8E-15 T 09-03-2017 UA74_RS20770 7e0ee536a90afafbae099d8682c5b267 285 Pfam PF01261 Xylose isomerase-like TIM barrel 26 216 2.2E-27 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS20770 7e0ee536a90afafbae099d8682c5b267 285 SUPERFAMILY SSF51658 1 263 2.09E-57 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS20770 7e0ee536a90afafbae099d8682c5b267 285 Gene3D G3DSA:3.20.20.150 2 283 8.5E-84 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 ProSitePatterns PS00622 LuxR-type HTH domain signature. 308 335 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 324 336 1.8E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 308 324 1.8E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 294 308 1.8E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 SUPERFAMILY SSF46894 284 348 2.93E-12 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 Pfam PF00196 Bacterial regulatory proteins, luxR family 294 347 4.3E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 SMART SM00421 291 348 3.6E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS19095 807dafa7d19252663d8d08afd28b5fac 367 Gene3D G3DSA:1.10.10.10 292 347 1.0E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23810 ef0e695cdb1fcbbffc2eebb0773dbebf 373 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 18 355 2.3E-121 T 09-03-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_RS23810 ef0e695cdb1fcbbffc2eebb0773dbebf 373 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 15 355 2.2E-126 T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_RS23810 ef0e695cdb1fcbbffc2eebb0773dbebf 373 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 15 357 47.32 T 09-03-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_RS23810 ef0e695cdb1fcbbffc2eebb0773dbebf 373 SUPERFAMILY SSF51726 18 357 3.66E-103 T 09-03-2017 UA74_RS23810 ef0e695cdb1fcbbffc2eebb0773dbebf 373 Gene3D G3DSA:3.20.20.210 13 357 5.0E-145 T 09-03-2017 UA74_RS23810 ef0e695cdb1fcbbffc2eebb0773dbebf 373 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 148 164 - T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_RS23810 ef0e695cdb1fcbbffc2eebb0773dbebf 373 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 31 40 - T 09-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_RS01650 2edc8580439b80e91269e38fee4cf4fc 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 7 157 2.3E-45 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_RS01650 2edc8580439b80e91269e38fee4cf4fc 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 6 158 30.374 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_RS01650 2edc8580439b80e91269e38fee4cf4fc 161 Pfam PF02542 YgbB family 7 156 4.7E-46 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_RS01650 2edc8580439b80e91269e38fee4cf4fc 161 Gene3D G3DSA:3.30.1330.50 6 157 3.0E-53 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_RS01650 2edc8580439b80e91269e38fee4cf4fc 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 40 55 - T 09-03-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_RS01650 2edc8580439b80e91269e38fee4cf4fc 161 SUPERFAMILY SSF69765 6 158 1.31E-49 T 09-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_RS17955 cbbcd3865471db25e3043c52e5f26f9f 243 SMART SM00422 1 70 5.3E-19 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS17955 cbbcd3865471db25e3043c52e5f26f9f 243 SUPERFAMILY SSF46955 4 99 7.69E-22 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS17955 cbbcd3865471db25e3043c52e5f26f9f 243 Pfam PF00376 MerR family regulatory protein 4 39 1.2E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS17955 cbbcd3865471db25e3043c52e5f26f9f 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.8E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS17955 cbbcd3865471db25e3043c52e5f26f9f 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 7.8E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS17955 cbbcd3865471db25e3043c52e5f26f9f 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.8E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS17955 cbbcd3865471db25e3043c52e5f26f9f 243 Gene3D G3DSA:1.10.1660.10 4 103 1.5E-23 T 09-03-2017 UA74_RS23895 e6464b22de130b5eafb60d9a804a9024 383 Gene3D G3DSA:3.40.50.720 4 143 2.1E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23895 e6464b22de130b5eafb60d9a804a9024 383 Gene3D G3DSA:3.30.360.10 144 327 1.8E-13 T 09-03-2017 UA74_RS23895 e6464b22de130b5eafb60d9a804a9024 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 127 2.3E-17 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS23895 e6464b22de130b5eafb60d9a804a9024 383 SUPERFAMILY SSF51735 4 155 1.48E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23895 e6464b22de130b5eafb60d9a804a9024 383 SUPERFAMILY SSF55347 137 287 3.05E-12 T 09-03-2017 UA74_RS03900 0d34c216afb96d392663747ce2a69a44 313 SUPERFAMILY SSF161098 72 299 1.57E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03900 0d34c216afb96d392663747ce2a69a44 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 297 2.4E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03900 0d34c216afb96d392663747ce2a69a44 313 Gene3D G3DSA:1.10.3720.10 79 308 2.2E-64 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS17685 536bbb0062724bd9be17a51f3bb1e744 189 Pfam PF01872 RibD C-terminal domain 4 175 7.3E-21 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS17685 536bbb0062724bd9be17a51f3bb1e744 189 Gene3D G3DSA:3.40.430.10 4 178 3.5E-24 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS17685 536bbb0062724bd9be17a51f3bb1e744 189 SUPERFAMILY SSF53597 3 178 1.96E-22 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 SUPERFAMILY SSF53223 10 129 1.18E-28 T 09-03-2017 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 Gene3D G3DSA:3.40.50.720 164 324 4.0E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 PIRSF PIRSF000185 6 392 4.2E-80 T 09-03-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 Gene3D G3DSA:3.40.192.10 12 124 5.1E-28 T 09-03-2017 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 SMART SM00839 161 388 4.2E-41 T 09-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 12 117 1.8E-18 T 09-03-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 58 72 7.1E-7 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 189 209 7.1E-7 T 09-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 SUPERFAMILY SSF51735 156 383 3.85E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 156 323 1.2E-32 T 09-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 UA74_RS07010 ca368f51b1069c4ca402e461bf94c0b4 397 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 66 79 - T 09-03-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 UA74_RS04305 99edf4420b243621cf3e14fdf74d718e 366 Gene3D G3DSA:3.40.190.10 15 143 1.2E-24 T 09-03-2017 UA74_RS04305 99edf4420b243621cf3e14fdf74d718e 366 Gene3D G3DSA:3.40.190.10 296 361 1.2E-24 T 09-03-2017 UA74_RS04305 99edf4420b243621cf3e14fdf74d718e 366 SUPERFAMILY SSF53850 44 361 4.63E-48 T 09-03-2017 UA74_RS04305 99edf4420b243621cf3e14fdf74d718e 366 Pfam PF13343 Bacterial extracellular solute-binding protein 91 336 3.5E-26 T 09-03-2017 UA74_RS04305 99edf4420b243621cf3e14fdf74d718e 366 Gene3D G3DSA:3.40.190.10 169 295 3.0E-20 T 09-03-2017 UA74_RS04305 99edf4420b243621cf3e14fdf74d718e 366 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 43 360 2.4E-68 T 09-03-2017 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 SUPERFAMILY SSF52540 316 528 1.38E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 Gene3D G3DSA:1.10.1750.10 552 653 1.3E-37 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 SMART SM00382 349 477 3.1E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 Gene3D G3DSA:3.40.50.300 313 481 4.4E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 SUPERFAMILY SSF48295 548 653 1.12E-34 T 09-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 382 396 1.8E-51 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 448 475 1.8E-51 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 414 428 1.8E-51 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 611 630 1.8E-51 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 350 370 1.8E-51 T 09-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 SMART SM00760 561 630 6.8E-34 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 Pfam PF00308 Bacterial dnaA protein 317 534 8.4E-102 T 09-03-2017 IPR013317 Chromosomal replication initiator protein DnaA UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 ProSitePatterns PS01008 DnaA protein signature. 611 630 - T 09-03-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 564 630 6.2E-28 T 09-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 Gene3D G3DSA:1.10.8.60 483 551 3.6E-28 T 09-03-2017 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 301 651 5.4E-149 T 09-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UA74_RS00005 25b8c4755b06bb017d31fc818e8ed80f 657 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 652 32.897 T 09-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UA74_RS26160 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 SUPERFAMILY SSF47413 10 71 2.76E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS26160 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 SMART SM00530 16 71 2.6E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS26160 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 Pfam PF13560 Helix-turn-helix domain 12 74 3.3E-11 T 09-03-2017 UA74_RS26160 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 Gene3D G3DSA:1.10.260.40 12 70 1.1E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18480 0667db49f14d24f46b8237622c9a525a 311 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 09-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS18480 0667db49f14d24f46b8237622c9a525a 311 Pfam PF00849 RNA pseudouridylate synthase 99 245 1.4E-17 T 09-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS18480 0667db49f14d24f46b8237622c9a525a 311 SUPERFAMILY SSF55120 83 295 5.44E-49 T 09-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_RS02560 c0eb915f17b003cc253c132f57754630 237 SUPERFAMILY SSF52833 12 171 2.46E-43 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS02560 c0eb915f17b003cc253c132f57754630 237 PIRSF PIRSF000216 3 222 2.6E-61 T 09-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02560 c0eb915f17b003cc253c132f57754630 237 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 18 163 1.1E-44 T 09-03-2017 UA74_RS02560 c0eb915f17b003cc253c132f57754630 237 Gene3D G3DSA:3.40.30.10 80 167 6.6E-8 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 Pfam PF12833 Helix-turn-helix domain 213 290 1.0E-16 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 SUPERFAMILY SSF46689 190 241 6.81E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 Gene3D G3DSA:1.10.10.60 245 292 2.2E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 286 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 Gene3D G3DSA:1.10.10.60 190 244 5.5E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 Pfam PF12852 Cupin 2 175 2.2E-42 T 09-03-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 SUPERFAMILY SSF46689 243 293 4.93E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14950 fa7b791a5ee4a52f1962c85396b5a370 315 SMART SM00342 207 290 7.3E-28 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS13385 53a7f0d50eb8d6b956890b839dafd4dc 437 Pfam PF13203 Putative metallopeptidase domain 86 301 2.3E-19 T 09-03-2017 IPR025154 Putative metallopeptidase domain UA74_RS13385 53a7f0d50eb8d6b956890b839dafd4dc 437 SUPERFAMILY SSF53300 310 420 3.71E-9 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS13385 53a7f0d50eb8d6b956890b839dafd4dc 437 Pfam PF09967 VWA-like domain (DUF2201) 310 432 4.1E-16 T 09-03-2017 IPR018698 VWA-like domain UA74_RS29275 f089342ff4eb2f6d79af4d3bd914d7a1 319 SUPERFAMILY SSF161098 40 308 4.97E-28 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS29275 f089342ff4eb2f6d79af4d3bd914d7a1 319 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 17 313 9.3E-84 T 09-03-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 UA74_RS29275 f089342ff4eb2f6d79af4d3bd914d7a1 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 311 3.2E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS29275 f089342ff4eb2f6d79af4d3bd914d7a1 319 Gene3D G3DSA:1.10.3720.10 33 317 2.9E-32 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS06980 57a8d05916a585246f73b42bc764b505 909 SUPERFAMILY SSF51445 607 790 2.74E-26 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS06980 57a8d05916a585246f73b42bc764b505 909 SUPERFAMILY SSF51445 476 574 2.74E-26 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS06980 57a8d05916a585246f73b42bc764b505 909 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 480 687 1.6E-7 T 09-03-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 UA74_RS06980 57a8d05916a585246f73b42bc764b505 909 Gene3D G3DSA:3.20.20.80 477 806 4.7E-28 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS03675 db2d00150ff7c58a0a3789578ec70bd6 188 Pfam PF14124 Domain of unknown function (DUF4291) 5 182 1.8E-69 T 09-03-2017 IPR025633 Protein of unknown function DUF4291 UA74_RS18360 402d7a772c8d6def0d41b3881b080a86 239 SUPERFAMILY SSF52317 7 194 1.8E-45 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS18360 402d7a772c8d6def0d41b3881b080a86 239 Pfam PF01965 DJ-1/PfpI family 7 172 8.7E-25 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS18360 402d7a772c8d6def0d41b3881b080a86 239 Gene3D G3DSA:3.40.50.880 7 196 9.9E-57 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS10635 228612cf6e8f64e3355e2a73730408d4 297 Pfam PF02374 Anion-transporting ATPase 7 254 1.2E-50 T 09-03-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_RS10635 228612cf6e8f64e3355e2a73730408d4 297 SUPERFAMILY SSF52540 7 256 2.43E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10635 228612cf6e8f64e3355e2a73730408d4 297 Gene3D G3DSA:3.40.50.300 7 165 3.2E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10635 228612cf6e8f64e3355e2a73730408d4 297 Gene3D G3DSA:3.40.50.300 198 254 3.2E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10635 228612cf6e8f64e3355e2a73730408d4 297 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 9 253 2.3E-53 T 09-03-2017 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 Gene3D G3DSA:3.30.565.10 296 419 2.4E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 1.5E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 373 1.5E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 1.5E-6 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 SMART SM00387 323 421 3.3E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 Pfam PF07730 Histidine kinase 219 284 9.0E-17 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 PIRSF PIRSF037434 6 423 2.2E-69 T 09-03-2017 IPR017205 Signal transduction histidine kinase, ChrS UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 SUPERFAMILY SSF55874 290 418 1.44E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS24385 27e583d28924df7588198fcd81b8d838 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 418 4.1E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05365 ab5fe3ff079101695e22c9155bff0a90 243 Pfam PF12697 Alpha/beta hydrolase family 15 238 7.0E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05365 ab5fe3ff079101695e22c9155bff0a90 243 Gene3D G3DSA:3.40.50.1820 12 241 1.9E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05365 ab5fe3ff079101695e22c9155bff0a90 243 SUPERFAMILY SSF53474 13 241 1.49E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22020 1e11ea087eec1e1e09209f72ab1c99c3 310 SUPERFAMILY SSF46689 78 140 2.69E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22020 1e11ea087eec1e1e09209f72ab1c99c3 310 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 156 299 1.5E-12 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS22020 1e11ea087eec1e1e09209f72ab1c99c3 310 Pfam PF00440 Bacterial regulatory proteins, tetR family 83 129 3.5E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22020 1e11ea087eec1e1e09209f72ab1c99c3 310 Gene3D G3DSA:1.10.357.10 72 305 3.2E-49 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22020 1e11ea087eec1e1e09209f72ab1c99c3 310 SUPERFAMILY SSF48498 158 303 2.11E-21 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 Pfam PF12706 Beta-lactamase superfamily domain 61 179 2.2E-13 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 SMART SM00849 32 226 1.2E-22 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 21 560 9.4E-146 T 09-03-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 372 419 1.7E-10 T 09-03-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 Hamap MF_01491 Ribonuclease J [rnj]. 15 563 40.335 T 09-03-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 375 403 - T 09-03-2017 IPR001587 Ribonuclease J, conserved site UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 Gene3D G3DSA:3.60.15.10 19 266 1.7E-71 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 SUPERFAMILY SSF56281 20 435 4.32E-93 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS09575 6fcff1d9f35511d6f7268099060c9782 563 PIRSF PIRSF004803 15 563 5.7E-194 T 09-03-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UA74_RS19985 138fcd77abc1f1e67c2a8c6ade422719 363 SMART SM00382 73 228 9.7E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS19985 138fcd77abc1f1e67c2a8c6ade422719 363 Gene3D G3DSA:3.40.50.300 59 232 1.4E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19985 138fcd77abc1f1e67c2a8c6ade422719 363 Pfam PF07728 AAA domain (dynein-related subfamily) 77 218 4.5E-33 T 09-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_RS19985 138fcd77abc1f1e67c2a8c6ade422719 363 SUPERFAMILY SSF52540 53 296 3.19E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02145 4a1157a957bdf200092064db8a973ec5 273 Gene3D G3DSA:3.40.50.150 44 153 2.2E-4 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS02145 4a1157a957bdf200092064db8a973ec5 273 SUPERFAMILY SSF53335 48 185 1.25E-8 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19015 ca977772b1f5e2f8938bca8ab664ccab 355 Pfam PF04055 Radical SAM superfamily 77 253 3.4E-11 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS19015 ca977772b1f5e2f8938bca8ab664ccab 355 SMART SM00729 73 299 0.0044 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS19015 ca977772b1f5e2f8938bca8ab664ccab 355 Gene3D G3DSA:3.20.20.70 80 269 2.0E-6 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS19015 ca977772b1f5e2f8938bca8ab664ccab 355 SUPERFAMILY SSF102114 76 290 6.28E-12 T 09-03-2017 UA74_RS29080 a259daa5a59e7f220444bedaa7790259 400 Gene3D G3DSA:3.40.640.10 46 254 2.0E-17 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS29080 a259daa5a59e7f220444bedaa7790259 400 SUPERFAMILY SSF53383 4 393 1.49E-76 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS29080 a259daa5a59e7f220444bedaa7790259 400 Pfam PF00266 Aminotransferase class-V 76 320 5.1E-18 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS29080 a259daa5a59e7f220444bedaa7790259 400 PIRSF PIRSF038800 1 398 1.3E-119 T 09-03-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 UA74_RS29080 a259daa5a59e7f220444bedaa7790259 400 Gene3D G3DSA:3.90.1150.10 255 393 3.0E-41 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS09960 5882999b480a8f8dec2c91a98b0e78c8 389 SUPERFAMILY SSF53335 11 48 1.12E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09960 5882999b480a8f8dec2c91a98b0e78c8 389 SUPERFAMILY SSF53335 95 219 1.12E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09960 5882999b480a8f8dec2c91a98b0e78c8 389 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 168 183 - T 09-03-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_RS09960 5882999b480a8f8dec2c91a98b0e78c8 389 Gene3D G3DSA:3.40.50.150 21 268 1.4E-54 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09960 5882999b480a8f8dec2c91a98b0e78c8 389 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 19 212 8.7E-29 T 09-03-2017 UA74_RS06115 3905ef83f914d958fb398b96c1c3c460 350 Gene3D G3DSA:2.60.40.10 45 129 9.7E-5 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS06115 3905ef83f914d958fb398b96c1c3c460 350 SUPERFAMILY SSF49265 45 129 4.47E-5 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS06115 3905ef83f914d958fb398b96c1c3c460 350 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 154 347 6.9E-16 T 09-03-2017 IPR004302 Chitin-binding protein, N-terminal UA74_RS06115 3905ef83f914d958fb398b96c1c3c460 350 SUPERFAMILY SSF81296 154 349 7.98E-20 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS06115 3905ef83f914d958fb398b96c1c3c460 350 Gene3D G3DSA:2.70.50.50 154 349 4.9E-23 T 09-03-2017 UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 367 1.6E-112 T 09-03-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 SUPERFAMILY SSF52540 1 231 7.84E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 SUPERFAMILY SSF52540 260 351 7.84E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 ProSitePatterns PS00618 RecF protein signature 2. 327 345 - T 09-03-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 Gene3D G3DSA:3.40.50.300 1 166 3.4E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 Gene3D G3DSA:3.40.50.300 255 358 3.4E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 385 92.49 T 09-03-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 UA74_RS00020 556e88a78c8b00aad0214f9059683071 385 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 359 1.1E-14 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal UA74_RS14790 1d3603086bf080722c7a0b7af15480f9 516 Gene3D G3DSA:3.30.43.10 53 111 3.3E-5 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS14790 1d3603086bf080722c7a0b7af15480f9 516 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 55 88 - T 09-03-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 UA74_RS14790 1d3603086bf080722c7a0b7af15480f9 516 Gene3D G3DSA:3.30.465.10 112 207 1.2E-9 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS14790 1d3603086bf080722c7a0b7af15480f9 516 Pfam PF01565 FAD binding domain 55 188 2.7E-22 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS14790 1d3603086bf080722c7a0b7af15480f9 516 SUPERFAMILY SSF56176 19 217 1.12E-37 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS04520 4748b96c1eb1e981bc578433c6ec2ba8 151 SUPERFAMILY SSF55961 6 146 1.15E-17 T 09-03-2017 UA74_RS04520 4748b96c1eb1e981bc578433c6ec2ba8 151 Gene3D G3DSA:3.30.530.20 9 146 5.8E-10 T 09-03-2017 IPR023393 START-like domain UA74_RS04520 4748b96c1eb1e981bc578433c6ec2ba8 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 7.7E-9 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS18645 619a086a5e47d040d9a4298704ae1c24 446 SUPERFAMILY SSF56176 5 200 4.46E-46 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS18645 619a086a5e47d040d9a4298704ae1c24 446 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 38 71 - T 09-03-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 UA74_RS18645 619a086a5e47d040d9a4298704ae1c24 446 Gene3D G3DSA:3.30.43.10 37 98 2.1E-10 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS18645 619a086a5e47d040d9a4298704ae1c24 446 Gene3D G3DSA:3.30.465.10 99 197 1.4E-10 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS18645 619a086a5e47d040d9a4298704ae1c24 446 Pfam PF01565 FAD binding domain 38 174 6.2E-30 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS00220 efe22ead510f0e1d514e630b36b2f0a9 189 SUPERFAMILY SSF81296 29 124 5.04E-23 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS00220 efe22ead510f0e1d514e630b36b2f0a9 189 Gene3D G3DSA:2.60.40.1220 29 124 2.5E-26 T 09-03-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like UA74_RS00220 efe22ead510f0e1d514e630b36b2f0a9 189 Pfam PF04234 CopC domain 30 123 1.4E-23 T 09-03-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 7.2E-34 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 7.2E-34 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 367 379 7.2E-34 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 7.2E-34 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 337 343 7.2E-34 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 7.2E-34 T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 28 45 - T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 401 524 3.6E-31 T 09-03-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 372 382 - T 09-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 Gene3D G3DSA:3.50.50.60 22 338 2.0E-47 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 SUPERFAMILY SSF51905 286 347 5.48E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 SUPERFAMILY SSF51905 23 249 5.48E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS27175 c02b041a0f62fd23a929dc8363e362f3 569 Pfam PF01266 FAD dependent oxidoreductase 24 372 5.9E-50 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 210 3.2E-4 T 09-03-2017 UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.0E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.0E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.0E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 SUPERFAMILY SSF51735 2 248 2.15E-69 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 2.6E-54 T 09-03-2017 UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 Gene3D G3DSA:3.40.50.720 2 248 3.7E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.3E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.3E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.3E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.3E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.3E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08520 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.3E-37 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00385 P450 superfamily signature 341 350 1.5E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00385 P450 superfamily signature 350 361 1.5E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00385 P450 superfamily signature 274 285 1.5E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00385 P450 superfamily signature 239 256 1.5E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 Pfam PF00067 Cytochrome P450 271 371 1.8E-19 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 160 175 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 350 361 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 292 319 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 197 219 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 320 335 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 96 107 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 143 159 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 341 350 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 PRINTS PR00359 B-class P450 signature 274 285 1.4E-55 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 Gene3D G3DSA:1.10.630.10 12 401 1.9E-120 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS12340 25dc9e2ab8ef548579aeb3622c2fc51a 401 SUPERFAMILY SSF48264 14 401 7.73E-96 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09440 d7d8eaa65bacb0c7ac838e89f43b6347 178 Gene3D G3DSA:3.90.1140.10 1 177 2.6E-25 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase UA74_RS09440 d7d8eaa65bacb0c7ac838e89f43b6347 178 SUPERFAMILY SSF55144 2 176 5.23E-18 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase UA74_RS09440 d7d8eaa65bacb0c7ac838e89f43b6347 178 Pfam PF13563 2'-5' RNA ligase superfamily 42 153 2.4E-9 T 09-03-2017 UA74_RS27055 69730f73493fbc418f615a859fb88a47 319 Pfam PF00682 HMGL-like 25 296 4.8E-47 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_RS27055 69730f73493fbc418f615a859fb88a47 319 SUPERFAMILY SSF51569 21 310 8.06E-67 T 09-03-2017 UA74_RS27055 69730f73493fbc418f615a859fb88a47 319 Gene3D G3DSA:3.20.20.70 23 310 4.4E-81 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS25145 01914428187c38cedd6015d4d43df387 375 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 372 9.0E-99 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS25145 01914428187c38cedd6015d4d43df387 375 Pfam PF02595 Glycerate kinase family 3 372 6.9E-109 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS25145 01914428187c38cedd6015d4d43df387 375 PIRSF PIRSF006078 1 374 3.6E-105 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS25145 01914428187c38cedd6015d4d43df387 375 Gene3D G3DSA:3.90.1510.10 42 274 1.5E-69 T 09-03-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 UA74_RS25145 01914428187c38cedd6015d4d43df387 375 SUPERFAMILY SSF110738 1 372 1.44E-96 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 24 475 2.4E-137 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 433 446 2.7E-29 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 293 315 2.7E-29 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 366 380 2.7E-29 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 62 81 2.7E-29 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 351 365 2.7E-29 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 50 456 6.1E-113 T 09-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 SUPERFAMILY SSF56601 22 467 4.07E-99 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 Gene3D G3DSA:3.40.710.10 36 80 1.6E-4 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS14590 0c7f064b0117a120cdd2343bd185ad9f 518 Gene3D G3DSA:3.40.710.10 235 476 5.8E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 Gene3D G3DSA:3.50.50.60 466 524 6.5E-94 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 Gene3D G3DSA:3.50.50.60 16 144 6.5E-94 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 Gene3D G3DSA:3.50.50.60 208 332 6.5E-94 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 SUPERFAMILY SSF54373 365 467 1.96E-12 T 09-03-2017 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 100 123 - T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 Pfam PF05199 GMC oxidoreductase 377 519 7.3E-34 T 09-03-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 274 288 - T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 Pfam PF00732 GMC oxidoreductase 17 314 2.2E-67 T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 Gene3D G3DSA:3.30.560.10 374 465 4.1E-12 T 09-03-2017 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 SUPERFAMILY SSF51905 14 303 1.68E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05430 7369b009f331a01d122b2f2d03ba2be9 529 SUPERFAMILY SSF51905 463 524 1.68E-66 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS28965 9edc608f2cbf86d4331fb798063775bb 323 Gene3D G3DSA:3.90.550.10 11 256 2.7E-37 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS28965 9edc608f2cbf86d4331fb798063775bb 323 Pfam PF00535 Glycosyl transferase family 2 12 137 9.7E-18 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS28965 9edc608f2cbf86d4331fb798063775bb 323 SUPERFAMILY SSF53448 9 237 1.62E-44 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS09555 e16df43ee6b077d2fe15f967690abd84 187 Gene3D G3DSA:1.10.1220.10 106 152 1.6E-6 T 09-03-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 UA74_RS09555 e16df43ee6b077d2fe15f967690abd84 187 Pfam PF05534 HicB family 110 140 2.7E-6 T 09-03-2017 IPR008651 Uncharacterised protein family HicB UA74_RS09555 e16df43ee6b077d2fe15f967690abd84 187 SUPERFAMILY SSF47598 105 157 4.89E-10 T 09-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 Gene3D G3DSA:1.20.120.530 89 219 4.2E-29 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 Gene3D G3DSA:1.10.10.10 2 69 4.7E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 SMART SM00345 7 66 4.0E-14 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 SUPERFAMILY SSF46785 2 70 2.4E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.1E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 Pfam PF07729 FCD domain 92 213 1.9E-29 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 SMART SM00895 92 214 8.3E-22 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 SUPERFAMILY SSF48008 88 220 1.28E-29 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.8E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS11920 3b59616c16313705a14ea74f2d1b5045 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.8E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 Pfam PF00041 Fibronectin type III domain 341 415 1.8E-11 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 SUPERFAMILY SSF51445 31 326 3.13E-76 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 150 159 - T 09-03-2017 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 SMART SM00060 338 415 1.7E-11 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 Pfam PF00553 Cellulose binding domain 435 535 4.5E-30 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 Gene3D G3DSA:3.20.20.80 32 327 7.2E-74 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 41 286 1.9E-36 T 09-03-2017 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 Gene3D G3DSA:2.60.40.10 336 426 2.3E-21 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 SUPERFAMILY SSF49265 335 429 8.6E-18 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 SMART SM00637 435 535 2.6E-43 T 09-03-2017 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 SUPERFAMILY SSF49384 431 536 1.74E-33 T 09-03-2017 IPR008965 Carbohydrate-binding domain GO:0030246 UA74_RS13115 8ba3c0fed987c660429fbd285cfc9e64 538 Gene3D G3DSA:2.60.40.290 434 537 4.4E-37 T 09-03-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 UA74_RS04065 5bec6cd704c84aaba5f0d9c828171dcf 124 Pfam PF01638 HxlR-like helix-turn-helix 32 114 2.7E-23 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS04065 5bec6cd704c84aaba5f0d9c828171dcf 124 SUPERFAMILY SSF46785 23 114 6.29E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04065 5bec6cd704c84aaba5f0d9c828171dcf 124 Gene3D G3DSA:1.10.10.10 19 116 2.8E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 SMART SM00421 137 194 2.4E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.7E-7 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.7E-7 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.7E-7 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 2.2E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 Gene3D G3DSA:1.10.10.10 144 200 6.7E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 Pfam PF00072 Response regulator receiver domain 4 114 2.9E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 Gene3D G3DSA:3.40.50.2300 1 143 1.9E-32 T 09-03-2017 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 SUPERFAMILY SSF46894 131 200 2.72E-17 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 SUPERFAMILY SSF52172 1 129 2.85E-29 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS05500 d907137e722c0b21dcbe1aff39589d1c 200 SMART SM00448 2 115 3.8E-22 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS23600 069bf03ff27fbb15cdc353c05ce0c289 95 Pfam PF14019 Protein of unknown function (DUF4235) 7 83 4.2E-25 T 09-03-2017 IPR025329 Protein of unknown function DUF4235 UA74_RS18280 9a994a784b4e90f2f4d5b25c454a3273 762 PIRSF PIRSF007663 1 740 9.1E-243 T 09-03-2017 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51 UA74_RS18280 9a994a784b4e90f2f4d5b25c454a3273 762 Gene3D G3DSA:2.70.98.50 2 379 1.6E-131 T 09-03-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 UA74_RS18280 9a994a784b4e90f2f4d5b25c454a3273 762 SUPERFAMILY SSF48208 251 701 3.23E-84 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS18280 9a994a784b4e90f2f4d5b25c454a3273 762 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 3 241 1.6E-68 T 09-03-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 UA74_RS27920 0069f30dbf91eae124d4ada9b528e093 218 Pfam PF12840 Helix-turn-helix domain 21 76 6.3E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27920 0069f30dbf91eae124d4ada9b528e093 218 SUPERFAMILY SSF46785 19 130 1.14E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27920 0069f30dbf91eae124d4ada9b528e093 218 Gene3D G3DSA:1.10.10.10 21 91 8.3E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27920 0069f30dbf91eae124d4ada9b528e093 218 SMART SM00418 19 95 1.1E-6 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS28150 a6e7057ff0469e79ab7f3cf20b6b3a36 154 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 12 141 3.1E-22 T 09-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 UA74_RS28150 a6e7057ff0469e79ab7f3cf20b6b3a36 154 SUPERFAMILY SSF52540 24 131 1.18E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28150 a6e7057ff0469e79ab7f3cf20b6b3a36 154 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 132 4.6E-29 T 09-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 UA74_RS28150 a6e7057ff0469e79ab7f3cf20b6b3a36 154 Gene3D G3DSA:3.40.50.300 4 152 1.4E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27100 e9b4481b8f74d5ca5926426bf4df558a 160 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 81 125 3.1E-15 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_RS27100 e9b4481b8f74d5ca5926426bf4df558a 160 SUPERFAMILY SSF46955 80 126 1.45E-5 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS27100 e9b4481b8f74d5ca5926426bf4df558a 160 Pfam PF12728 Helix-turn-helix domain 80 127 1.9E-12 T 09-03-2017 UA74_RS00360 67c775991fdaecc3888ebd5f29c17b28 136 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 131 5.3E-36 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS00360 67c775991fdaecc3888ebd5f29c17b28 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 86 1.4E-15 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS00360 67c775991fdaecc3888ebd5f29c17b28 136 Gene3D G3DSA:2.30.110.10 6 131 4.4E-27 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS00360 67c775991fdaecc3888ebd5f29c17b28 136 SUPERFAMILY SSF50475 6 130 1.88E-31 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS03110 2b40ccf80060da414bfd87960cf34569 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 2.9E-38 T 09-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 UA74_RS03110 2b40ccf80060da414bfd87960cf34569 73 SUPERFAMILY SSF50249 4 72 3.94E-27 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS03110 2b40ccf80060da414bfd87960cf34569 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.567 T 09-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 UA74_RS03110 2b40ccf80060da414bfd87960cf34569 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 2.2E-29 T 09-03-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 UA74_RS03110 2b40ccf80060da414bfd87960cf34569 73 Gene3D G3DSA:2.40.50.140 3 73 2.7E-39 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS13680 5bd867542443048d0750400c3c65714c 232 PRINTS PR00400 Tetracycline repressor protein signature 26 49 5.4E-12 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 PRINTS PR00400 Tetracycline repressor protein signature 187 201 5.4E-12 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 PRINTS PR00400 Tetracycline repressor protein signature 78 97 5.4E-12 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 SUPERFAMILY SSF48498 77 205 3.67E-27 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS13680 5bd867542443048d0750400c3c65714c 232 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 203 4.4E-13 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 SUPERFAMILY SSF46689 1 68 3.69E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.0E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.0E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.2E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13680 5bd867542443048d0750400c3c65714c 232 Gene3D G3DSA:1.10.357.10 2 206 6.1E-59 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS13730 13268867d06d59285bcaa1504601e1ff 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 284 9.2E-35 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS00675 1ae03ceef8ddb4c036341bd53c0cc405 638 Pfam PF13641 Glycosyltransferase like family 2 175 428 1.3E-35 T 09-03-2017 UA74_RS00675 1ae03ceef8ddb4c036341bd53c0cc405 638 SUPERFAMILY SSF53448 343 430 2.44E-22 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00675 1ae03ceef8ddb4c036341bd53c0cc405 638 SUPERFAMILY SSF53448 206 311 2.44E-22 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00675 1ae03ceef8ddb4c036341bd53c0cc405 638 Gene3D G3DSA:3.90.550.10 223 427 2.4E-12 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 Pfam PF01019 Gamma-glutamyltranspeptidase 35 592 7.8E-129 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 SUPERFAMILY SSF56235 404 599 4.05E-127 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 SUPERFAMILY SSF56235 6 369 4.05E-127 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 8.7E-27 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 487 504 8.7E-27 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 409 427 8.7E-27 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 463 478 8.7E-27 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 8.7E-27 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS20230 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 8.7E-27 T 09-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 UA74_RS03915 60b19a0b62929c12d0d24a163ddad6f8 509 Gene3D G3DSA:3.20.20.80 46 364 7.3E-34 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS03915 60b19a0b62929c12d0d24a163ddad6f8 509 SUPERFAMILY SSF51445 28 390 8.35E-110 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS03915 60b19a0b62929c12d0d24a163ddad6f8 509 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 301 501 4.7E-43 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UA74_RS03915 60b19a0b62929c12d0d24a163ddad6f8 509 SUPERFAMILY SSF51011 381 508 8.63E-35 T 09-03-2017 UA74_RS03915 60b19a0b62929c12d0d24a163ddad6f8 509 SMART SM00813 301 501 4.0E-79 T 09-03-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UA74_RS14905 0231aa766e8da1456161680cbb730093 85 Gene3D G3DSA:3.90.820.10 21 79 9.1E-32 T 09-03-2017 UA74_RS14905 0231aa766e8da1456161680cbb730093 85 SMART SM00923 13 63 4.6E-21 T 09-03-2017 IPR005153 MbtH-like protein UA74_RS14905 0231aa766e8da1456161680cbb730093 85 Pfam PF03621 MbtH-like protein 17 63 2.1E-22 T 09-03-2017 IPR005153 MbtH-like protein UA74_RS14905 0231aa766e8da1456161680cbb730093 85 SUPERFAMILY SSF160582 17 79 4.45E-28 T 09-03-2017 UA74_RS17075 fb83e941d1c799d2d5c589f131ddf1f5 275 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 270 8.2E-6 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS17075 fb83e941d1c799d2d5c589f131ddf1f5 275 Gene3D G3DSA:3.40.50.300 11 262 1.3E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17075 fb83e941d1c799d2d5c589f131ddf1f5 275 SUPERFAMILY SSF52540 12 260 1.61E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17075 fb83e941d1c799d2d5c589f131ddf1f5 275 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS17075 fb83e941d1c799d2d5c589f131ddf1f5 275 SMART SM00382 40 238 5.6E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS17075 fb83e941d1c799d2d5c589f131ddf1f5 275 Pfam PF00005 ABC transporter 32 188 1.1E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 SMART SM01350 184 471 5.6E-197 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 184 470 8.1E-119 T 09-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 Gene3D G3DSA:3.40.50.720 7 185 8.6E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 259 271 - T 09-03-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 Gene3D G3DSA:1.20.5.320 439 476 3.1E-20 T 09-03-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 11 471 8.3E-200 T 09-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 PIRSF PIRSF000109 4 479 9.4E-195 T 09-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 SUPERFAMILY SSF51735 9 182 4.56E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 Gene3D G3DSA:1.10.1040.10 186 437 3.0E-100 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 9 32 5.2E-80 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 173 201 5.2E-80 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 5.2E-80 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 255 282 5.2E-80 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 72 101 5.2E-80 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 125 150 5.2E-80 T 09-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 174 9.3E-49 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS21360 a57f4331d1061e91bdff74d581d9a9b6 479 SUPERFAMILY SSF48179 182 472 1.08E-115 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS09145 90ad913d5b1e56524c8279df46fdd9eb 126 Pfam PF01850 PIN domain 3 118 3.8E-15 T 09-03-2017 IPR002716 PIN domain UA74_RS09145 90ad913d5b1e56524c8279df46fdd9eb 126 Gene3D G3DSA:3.40.50.1010 1 124 4.8E-6 T 09-03-2017 IPR029060 PIN domain-like UA74_RS09145 90ad913d5b1e56524c8279df46fdd9eb 126 SUPERFAMILY SSF88723 1 124 4.49E-21 T 09-03-2017 IPR029060 PIN domain-like UA74_RS10180 3506585b67f327a8eaaf387650a1a5f2 488 Gene3D G3DSA:1.20.1250.20 276 456 1.9E-17 T 09-03-2017 UA74_RS10180 3506585b67f327a8eaaf387650a1a5f2 488 Pfam PF07690 Major Facilitator Superfamily 28 289 2.7E-28 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS10180 3506585b67f327a8eaaf387650a1a5f2 488 SUPERFAMILY SSF103473 9 208 5.62E-68 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS10180 3506585b67f327a8eaaf387650a1a5f2 488 SUPERFAMILY SSF103473 261 455 5.62E-68 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS10180 3506585b67f327a8eaaf387650a1a5f2 488 Gene3D G3DSA:1.20.1250.20 19 209 2.7E-35 T 09-03-2017 UA74_RS12920 ebb5b00a640e0d724b280ff876f0751b 376 Pfam PF02163 Peptidase family M50 151 198 1.1E-6 T 09-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 UA74_RS12920 ebb5b00a640e0d724b280ff876f0751b 376 Gene3D G3DSA:3.10.580.10 271 373 5.0E-5 T 09-03-2017 UA74_RS12920 ebb5b00a640e0d724b280ff876f0751b 376 PIRSF PIRSF006404 14 376 7.8E-62 T 09-03-2017 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS UA74_RS12920 ebb5b00a640e0d724b280ff876f0751b 376 SUPERFAMILY SSF54631 263 373 1.39E-5 T 09-03-2017 UA74_RS15105 de81729ca4135be1d834da4eec1eb565 178 Pfam PF03358 NADPH-dependent FMN reductase 6 133 6.9E-32 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS15105 de81729ca4135be1d834da4eec1eb565 178 SUPERFAMILY SSF52218 6 154 3.26E-35 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS15105 de81729ca4135be1d834da4eec1eb565 178 Gene3D G3DSA:3.40.50.360 6 168 5.4E-41 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS08425 e1d1ca361214dbe64087bdb17d0026ce 127 Gene3D G3DSA:3.10.180.10 14 122 4.5E-22 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS08425 e1d1ca361214dbe64087bdb17d0026ce 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 108 1.6E-7 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS08425 e1d1ca361214dbe64087bdb17d0026ce 127 SUPERFAMILY SSF54593 14 116 7.52E-19 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS04855 aa51c09717fac01636a8511f63e5bd1c 456 Gene3D G3DSA:3.30.830.10 40 224 2.3E-20 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 UA74_RS04855 aa51c09717fac01636a8511f63e5bd1c 456 Gene3D G3DSA:3.30.830.10 252 439 4.0E-22 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 UA74_RS04855 aa51c09717fac01636a8511f63e5bd1c 456 Pfam PF00675 Insulinase (Peptidase family M16) 73 185 4.1E-5 T 09-03-2017 IPR011765 Peptidase M16, N-terminal UA74_RS04855 aa51c09717fac01636a8511f63e5bd1c 456 Pfam PF05193 Peptidase M16 inactive domain 205 371 6.2E-14 T 09-03-2017 IPR007863 Peptidase M16, C-terminal UA74_RS04855 aa51c09717fac01636a8511f63e5bd1c 456 SUPERFAMILY SSF63411 260 451 1.13E-33 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_RS04855 aa51c09717fac01636a8511f63e5bd1c 456 SUPERFAMILY SSF63411 39 242 1.56E-25 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_RS19595 cf157b9c787b4afce5d77e1b89c0957b 398 Pfam PF07690 Major Facilitator Superfamily 19 296 2.8E-23 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS19595 cf157b9c787b4afce5d77e1b89c0957b 398 Gene3D G3DSA:1.20.1250.20 10 179 5.4E-19 T 09-03-2017 UA74_RS19595 cf157b9c787b4afce5d77e1b89c0957b 398 SUPERFAMILY SSF103473 5 387 2.22E-47 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19595 cf157b9c787b4afce5d77e1b89c0957b 398 Gene3D G3DSA:1.20.1250.20 207 385 4.9E-15 T 09-03-2017 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 PIRSF PIRSF000538 1 439 5.8E-132 T 09-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 SUPERFAMILY SSF53067 246 436 4.83E-44 T 09-03-2017 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 Gene3D G3DSA:3.30.420.40 2 242 1.0E-61 T 09-03-2017 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 TIGRFAM TIGR01312 XylB: xylulokinase 2 435 3.5E-116 T 09-03-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 255 432 1.1E-26 T 09-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 2 242 8.4E-61 T 09-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 SUPERFAMILY SSF53067 2 245 2.59E-64 T 09-03-2017 UA74_RS09770 9abd106e1b9ef4bc18209d0a83db04b2 480 Gene3D G3DSA:3.30.420.40 246 436 1.9E-40 T 09-03-2017 UA74_RS11685 922ec942be5abffdf13b43e9b3fb390c 470 ProSitePatterns PS00571 Amidases signature. 156 187 - T 09-03-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UA74_RS11685 922ec942be5abffdf13b43e9b3fb390c 470 Gene3D G3DSA:3.90.1300.10 5 466 7.9E-137 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS11685 922ec942be5abffdf13b43e9b3fb390c 470 SUPERFAMILY SSF75304 5 466 1.14E-133 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS11685 922ec942be5abffdf13b43e9b3fb390c 470 Pfam PF01425 Amidase 28 448 1.1E-104 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS16925 c7e2e71b1526adfd84ae082d4dd7dc8a 126 Gene3D G3DSA:3.10.450.50 4 124 3.4E-39 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS16925 c7e2e71b1526adfd84ae082d4dd7dc8a 126 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 1 124 26.472 T 09-03-2017 IPR023006 Uncharacterised protein family UPF0225 UA74_RS16925 c7e2e71b1526adfd84ae082d4dd7dc8a 126 SUPERFAMILY SSF54427 25 124 1.75E-32 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS01575 86da80bc169cc93a5e2bfbe3515e504a 261 Pfam PF03309 Type III pantothenate kinase 3 208 1.0E-60 T 09-03-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_RS01575 86da80bc169cc93a5e2bfbe3515e504a 261 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 256 2.4E-70 T 09-03-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_RS01575 86da80bc169cc93a5e2bfbe3515e504a 261 SUPERFAMILY SSF53067 2 124 2.96E-26 T 09-03-2017 UA74_RS01575 86da80bc169cc93a5e2bfbe3515e504a 261 SUPERFAMILY SSF53067 126 259 5.44E-33 T 09-03-2017 UA74_RS01575 86da80bc169cc93a5e2bfbe3515e504a 261 Gene3D G3DSA:3.30.420.40 96 259 5.4E-46 T 09-03-2017 UA74_RS01575 86da80bc169cc93a5e2bfbe3515e504a 261 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 260 32.916 T 09-03-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_RS06260 82316a13f0626edb1cd366480402131c 197 Pfam PF02632 BioY family 51 189 1.3E-34 T 09-03-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UA74_RS06260 82316a13f0626edb1cd366480402131c 197 PIRSF PIRSF016661 13 197 6.5E-37 T 09-03-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 Pfam PF00067 Cytochrome P450 239 338 1.8E-17 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 SUPERFAMILY SSF48264 3 370 5.37E-89 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 317 328 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 240 251 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 258 285 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 121 136 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 104 120 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 158 180 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 308 317 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00359 B-class P450 signature 55 66 3.0E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 Gene3D G3DSA:1.10.630.10 3 370 5.9E-117 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 310 319 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00385 P450 superfamily signature 317 328 1.8E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00385 P450 superfamily signature 205 222 1.8E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00385 P450 superfamily signature 240 251 1.8E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20390 add8fcec928f8453c0738f3a85cce29a 374 PRINTS PR00385 P450 superfamily signature 308 317 1.8E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09780 3c374a94d98b0c07500f381ece9b1162 236 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 13 232 1.1E-52 T 09-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase UA74_RS09780 3c374a94d98b0c07500f381ece9b1162 236 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 8 231 5.4E-71 T 09-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase UA74_RS09780 3c374a94d98b0c07500f381ece9b1162 236 SUPERFAMILY SSF64438 3 233 3.3E-72 T 09-03-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic UA74_RS09780 3c374a94d98b0c07500f381ece9b1162 236 Gene3D G3DSA:3.60.140.10 2 234 1.6E-82 T 09-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase UA74_RS06275 3fdcf5616dbd64c0161892d46d667ca1 351 SUPERFAMILY SSF51735 150 323 3.51E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06275 3fdcf5616dbd64c0161892d46d667ca1 351 SMART SM00829 10 346 6.2E-11 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS06275 3fdcf5616dbd64c0161892d46d667ca1 351 Gene3D G3DSA:3.40.50.720 178 295 1.0E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06275 3fdcf5616dbd64c0161892d46d667ca1 351 Pfam PF00107 Zinc-binding dehydrogenase 183 307 1.9E-27 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS06275 3fdcf5616dbd64c0161892d46d667ca1 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 141 6.0E-12 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS06275 3fdcf5616dbd64c0161892d46d667ca1 351 SUPERFAMILY SSF50129 1 179 1.89E-34 T 09-03-2017 IPR011032 GroES-like UA74_RS06275 3fdcf5616dbd64c0161892d46d667ca1 351 Gene3D G3DSA:3.90.180.10 1 177 8.8E-38 T 09-03-2017 IPR011032 GroES-like UA74_RS26725 c4d973f14a2ba4b33994accf98957105 227 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 168 223 2.4E-22 T 09-03-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal UA74_RS26725 c4d973f14a2ba4b33994accf98957105 227 SUPERFAMILY SSF69754 1 106 7.06E-26 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 UA74_RS26725 c4d973f14a2ba4b33994accf98957105 227 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 8.3E-22 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 UA74_RS26725 c4d973f14a2ba4b33994accf98957105 227 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 4.5E-29 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 UA74_RS26725 c4d973f14a2ba4b33994accf98957105 227 Gene3D G3DSA:3.30.160.100 1 101 1.8E-29 T 09-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 UA74_RS15555 aeab2b8c05850a5835d95f108e145c7c 339 Gene3D G3DSA:3.20.20.100 1 313 3.3E-87 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS15555 aeab2b8c05850a5835d95f108e145c7c 339 Pfam PF00248 Aldo/keto reductase family 16 313 3.5E-67 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS15555 aeab2b8c05850a5835d95f108e145c7c 339 SUPERFAMILY SSF51430 1 313 6.42E-92 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS09340 ac77edf342d981f5c48e6b59c8f8d85b 156 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 5 114 2.0E-19 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 UA74_RS09340 ac77edf342d981f5c48e6b59c8f8d85b 156 Gene3D G3DSA:3.30.300.20 5 121 8.7E-33 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS09340 ac77edf342d981f5c48e6b59c8f8d85b 156 SUPERFAMILY SSF89919 3 116 4.19E-26 T 09-03-2017 IPR023799 Ribosome-binding factor A domain UA74_RS09340 ac77edf342d981f5c48e6b59c8f8d85b 156 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 120 18.216 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 UA74_RS09340 ac77edf342d981f5c48e6b59c8f8d85b 156 Pfam PF02033 Ribosome-binding factor A 6 113 1.4E-24 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 UA74_RS09340 ac77edf342d981f5c48e6b59c8f8d85b 156 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 09-03-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 UA74_RS09340 ac77edf342d981f5c48e6b59c8f8d85b 156 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 6.0E-25 T 09-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 UA74_RS14715 e47bb456bf30f4ef947db710154d67cd 161 SUPERFAMILY SSF55729 4 145 6.23E-30 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14715 e47bb456bf30f4ef947db710154d67cd 161 Pfam PF13302 Acetyltransferase (GNAT) domain 9 141 5.1E-19 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS14715 e47bb456bf30f4ef947db710154d67cd 161 Gene3D G3DSA:3.40.630.30 3 151 6.7E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS00290 83d0e1bdbb997144b9845e2563f4aa4b 433 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 149 307 2.8E-15 T 09-03-2017 IPR031811 AlgX, SGNH hydrolase-like domain UA74_RS06350 85471ada321582cd20fe3d8b1d4c9166 212 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 8 200 3.0E-47 T 09-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 UA74_RS06350 85471ada321582cd20fe3d8b1d4c9166 212 Gene3D G3DSA:3.90.950.10 5 206 5.7E-78 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_RS06350 85471ada321582cd20fe3d8b1d4c9166 212 Pfam PF01725 Ham1 family 8 200 1.9E-54 T 09-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 UA74_RS06350 85471ada321582cd20fe3d8b1d4c9166 212 SUPERFAMILY SSF52972 5 204 2.41E-62 T 09-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_RS06350 85471ada321582cd20fe3d8b1d4c9166 212 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 6 205 48.863 T 09-03-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 UA74_RS13010 62b056da9d3eb3dd606c10803331b0dc 325 Pfam PF13280 WYL domain 147 318 1.0E-26 T 09-03-2017 IPR026881 WYL domain UA74_RS18030 1307cec25f9c46e05c468f1d96947822 583 Pfam PF01593 Flavin containing amine oxidoreductase 22 390 1.8E-13 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS18030 1307cec25f9c46e05c468f1d96947822 583 Gene3D G3DSA:3.50.50.60 13 116 5.1E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18030 1307cec25f9c46e05c468f1d96947822 583 Gene3D G3DSA:3.50.50.60 226 352 5.1E-28 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18030 1307cec25f9c46e05c468f1d96947822 583 SUPERFAMILY SSF51905 10 343 4.02E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18030 1307cec25f9c46e05c468f1d96947822 583 SUPERFAMILY SSF51905 497 531 4.02E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 SUPERFAMILY SSF48452 405 525 3.7E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 SUPERFAMILY SSF56112 11 304 8.79E-71 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 Gene3D G3DSA:3.30.200.20 3 73 6.7E-20 T 09-03-2017 UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 Gene3D G3DSA:1.10.510.10 74 261 4.8E-45 T 09-03-2017 UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 SMART SM00220 7 271 3.5E-53 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 Pfam PF00069 Protein kinase domain 11 258 8.6E-45 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS20620 8e7bc78b80dde08b52b5ae23a453a552 541 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 SUPERFAMILY SSF56645 11 232 1.57E-69 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 2.0E-47 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 SUPERFAMILY SSF47203 233 383 2.09E-54 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 4.3E-24 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 PIRSF PIRSF016578 4 377 3.8E-22 T 09-03-2017 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 Gene3D G3DSA:1.20.140.10 223 383 1.1E-61 T 09-03-2017 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 Gene3D G3DSA:1.10.540.10 12 123 1.9E-32 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 Gene3D G3DSA:2.40.110.10 126 222 4.6E-35 T 09-03-2017 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 122 3.5E-27 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS02275 b6a2855c7183c8c7d111c751037431d0 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 Gene3D G3DSA:3.40.50.2000 423 716 6.0E-79 T 09-03-2017 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 Gene3D G3DSA:3.40.50.2000 24 422 6.1E-87 T 09-03-2017 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 SUPERFAMILY SSF53756 5 746 3.04E-194 T 09-03-2017 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 111 712 6.0E-229 T 09-03-2017 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 PIRSF PIRSF000460 1 800 2.7E-251 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 602 614 - T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 Pfam PF11897 Protein of unknown function (DUF3417) 13 123 8.8E-33 T 09-03-2017 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 Pfam PF00343 Carbohydrate phosphorylase 128 173 2.5E-4 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_RS06365 13111c18a7a021a36b0ff7e376510578 852 Pfam PF00343 Carbohydrate phosphorylase 278 624 1.3E-16 T 09-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_RS20020 f6727335d371e1abac8d05ecc68d86ac 376 Gene3D G3DSA:3.40.710.10 38 345 4.1E-78 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS20020 f6727335d371e1abac8d05ecc68d86ac 376 Pfam PF00144 Beta-lactamase 35 347 4.2E-60 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS20020 f6727335d371e1abac8d05ecc68d86ac 376 SUPERFAMILY SSF56601 26 346 1.98E-74 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 270 4.7E-79 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 SUPERFAMILY SSF51735 3 162 1.07E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 166 270 6.9E-37 T 09-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 102 7.4E-21 T 09-03-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 Gene3D G3DSA:3.40.50.720 3 162 4.8E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 PIRSF PIRSF000193 1 273 7.6E-69 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 SUPERFAMILY SSF48179 165 272 2.55E-34 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 270 26.873 T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 226 248 - T 09-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 UA74_RS02240 ad7b93775238321221036bedb3b8ff29 283 Gene3D G3DSA:1.10.3730.10 165 270 8.2E-39 T 09-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UA74_RS03280 49f0c5457a7f3e7658b886ca948fd0a3 213 Gene3D G3DSA:3.40.630.30 9 198 6.6E-47 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS03280 49f0c5457a7f3e7658b886ca948fd0a3 213 SUPERFAMILY SSF55729 21 191 3.81E-37 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS03280 49f0c5457a7f3e7658b886ca948fd0a3 213 Pfam PF13302 Acetyltransferase (GNAT) domain 24 168 2.9E-13 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 293 1.7E-16 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 Gene3D G3DSA:3.50.50.60 14 143 5.4E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 1.9E-9 T 09-03-2017 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 1.9E-9 T 09-03-2017 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 1.9E-9 T 09-03-2017 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 SUPERFAMILY SSF51905 9 313 2.28E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 Gene3D G3DSA:3.50.50.60 144 241 6.2E-36 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 16 38 4.6E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 153 4.6E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 4.6E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 156 180 4.6E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 296 4.6E-16 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS16820 ec49be7dfd06dfea90dfb89252dc0508 334 Gene3D G3DSA:3.50.50.60 247 316 3.9E-5 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25185 1c5b39c00b345122ddd3baedec6b64bc 366 SUPERFAMILY SSF56752 10 363 4.45E-109 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 UA74_RS25185 1c5b39c00b345122ddd3baedec6b64bc 366 Gene3D G3DSA:3.20.10.10 180 352 4.9E-64 T 09-03-2017 UA74_RS25185 1c5b39c00b345122ddd3baedec6b64bc 366 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 363 8.7E-129 T 09-03-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 UA74_RS25185 1c5b39c00b345122ddd3baedec6b64bc 366 Pfam PF01063 Amino-transferase class IV 75 319 1.9E-27 T 09-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 UA74_RS25185 1c5b39c00b345122ddd3baedec6b64bc 366 Gene3D G3DSA:3.30.470.10 22 179 3.4E-67 T 09-03-2017 UA74_RS25185 1c5b39c00b345122ddd3baedec6b64bc 366 PIRSF PIRSF006468 5 365 1.5E-127 T 09-03-2017 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 UA74_RS11950 1e4e6ea8769b37d7d00f6932ef6919d2 379 Pfam PF04909 Amidohydrolase 276 377 2.8E-22 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS11950 1e4e6ea8769b37d7d00f6932ef6919d2 379 Pfam PF04909 Amidohydrolase 7 180 7.8E-16 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS11950 1e4e6ea8769b37d7d00f6932ef6919d2 379 SUPERFAMILY SSF51556 267 377 8.36E-34 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS11950 1e4e6ea8769b37d7d00f6932ef6919d2 379 SUPERFAMILY SSF51556 6 175 8.36E-34 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS11950 1e4e6ea8769b37d7d00f6932ef6919d2 379 Gene3D G3DSA:3.20.20.140 270 378 1.5E-30 T 09-03-2017 UA74_RS11950 1e4e6ea8769b37d7d00f6932ef6919d2 379 Gene3D G3DSA:3.20.20.140 5 183 2.9E-35 T 09-03-2017 UA74_RS11040 4b641f3974c6f550405f651d92078aa2 221 Pfam PF03070 TENA/THI-4/PQQC family 17 210 3.9E-17 T 09-03-2017 IPR004305 Thiaminase-2/PQQC UA74_RS11040 4b641f3974c6f550405f651d92078aa2 221 SUPERFAMILY SSF48613 1 220 1.11E-34 T 09-03-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS11040 4b641f3974c6f550405f651d92078aa2 221 Gene3D G3DSA:1.20.910.10 2 220 5.2E-40 T 09-03-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS23030 7968a49788b485f12928ada28577eea2 318 Pfam PF00248 Aldo/keto reductase family 21 316 8.6E-59 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS23030 7968a49788b485f12928ada28577eea2 318 SUPERFAMILY SSF51430 9 316 4.32E-79 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS23030 7968a49788b485f12928ada28577eea2 318 Gene3D G3DSA:3.20.20.100 14 316 6.0E-77 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS05905 c088e4cd7640f2802bfc6fd00143b60e 99 SUPERFAMILY SSF46785 6 79 2.5E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05905 c088e4cd7640f2802bfc6fd00143b60e 99 Gene3D G3DSA:1.10.10.10 18 79 5.5E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 165 176 - T 09-03-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 399 415 3.0E-17 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 206 219 3.0E-17 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 3.0E-17 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 400 410 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 SUPERFAMILY SSF52743 142 478 4.71E-66 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 Gene3D G3DSA:3.40.50.200 139 478 2.2E-69 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 Pfam PF00082 Subtilase family 162 444 9.0E-40 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS08265 ecb8a3eed1502d514b86bc492ec09c2c 479 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 210 220 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS01525 9272102db57febaf5448abc631d87270 267 SUPERFAMILY SSF51717 1 262 3.14E-88 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS01525 9272102db57febaf5448abc631d87270 267 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 260 9.2E-88 T 09-03-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 UA74_RS01525 9272102db57febaf5448abc631d87270 267 Pfam PF00809 Pterin binding enzyme 1 246 6.6E-83 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS01525 9272102db57febaf5448abc631d87270 267 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS01525 9272102db57febaf5448abc631d87270 267 Gene3D G3DSA:3.20.20.20 1 263 1.8E-101 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 Gene3D G3DSA:3.40.50.300 1 240 1.3E-82 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 Gene3D G3DSA:3.30.70.260 254 327 1.8E-7 T 09-03-2017 UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SUPERFAMILY SSF52540 1 238 9.54E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 Pfam PF09383 NIL domain 262 327 2.2E-9 T 09-03-2017 IPR018449 NIL domain UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SUPERFAMILY SSF55021 242 327 5.84E-8 T 09-03-2017 UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SMART SM00930 257 330 1.0E-10 T 09-03-2017 IPR018449 NIL domain UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 Pfam PF00005 ABC transporter 21 169 2.8E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SMART SM00382 30 217 3.8E-19 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS05715 55fa06fe2e7e81bb18920d9167d3f7ac 298 Gene3D G3DSA:3.40.50.720 2 101 4.6E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05715 55fa06fe2e7e81bb18920d9167d3f7ac 298 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 297 5.9E-24 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 UA74_RS05715 55fa06fe2e7e81bb18920d9167d3f7ac 298 Gene3D G3DSA:3.40.50.720 102 276 2.9E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05715 55fa06fe2e7e81bb18920d9167d3f7ac 298 SUPERFAMILY SSF51735 93 276 8.35E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05715 55fa06fe2e7e81bb18920d9167d3f7ac 298 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 275 1.6E-52 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS05715 55fa06fe2e7e81bb18920d9167d3f7ac 298 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 185 207 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS05715 55fa06fe2e7e81bb18920d9167d3f7ac 298 SUPERFAMILY SSF52283 2 115 5.29E-23 T 09-03-2017 UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 Gene3D G3DSA:1.10.10.60 2 40 7.9E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 SUPERFAMILY SSF46689 4 57 2.14E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 2.9E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 2.9E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 2.4E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 Gene3D G3DSA:1.10.357.10 45 175 2.2E-27 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 SUPERFAMILY SSF48498 69 175 7.42E-19 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS05515 a97973de1d776c50deefffa7a0e21a86 213 Pfam PF16859 Bacterial transcriptional repressor C-terminal 61 170 9.9E-24 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS01145 a82dc38fb549e6a5deb4d0ee70882fb2 156 Gene3D G3DSA:1.10.10.410 94 155 6.4E-17 T 09-03-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal UA74_RS01145 a82dc38fb549e6a5deb4d0ee70882fb2 156 Pfam PF09424 Yqey-like protein 5 154 9.4E-42 T 09-03-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial UA74_RS01145 a82dc38fb549e6a5deb4d0ee70882fb2 156 Gene3D G3DSA:1.10.1510.10 3 93 1.7E-25 T 09-03-2017 UA74_RS01145 a82dc38fb549e6a5deb4d0ee70882fb2 156 SUPERFAMILY SSF89095 4 154 2.41E-30 T 09-03-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 UA74_RS27290 42810f1efcff6fcf0a6b84610c32f6c2 402 SUPERFAMILY SSF55347 142 317 5.07E-37 T 09-03-2017 UA74_RS27290 42810f1efcff6fcf0a6b84610c32f6c2 402 Gene3D G3DSA:3.30.360.10 157 298 2.4E-49 T 09-03-2017 UA74_RS27290 42810f1efcff6fcf0a6b84610c32f6c2 402 Gene3D G3DSA:3.30.360.10 346 391 2.4E-49 T 09-03-2017 UA74_RS27290 42810f1efcff6fcf0a6b84610c32f6c2 402 SUPERFAMILY SSF51735 5 168 3.55E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27290 42810f1efcff6fcf0a6b84610c32f6c2 402 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 220 1.1E-11 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS27290 42810f1efcff6fcf0a6b84610c32f6c2 402 Gene3D G3DSA:3.40.50.720 4 156 8.5E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27290 42810f1efcff6fcf0a6b84610c32f6c2 402 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 126 1.1E-23 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS27880 1506e8f84ddb92a51c0b1ccafbb94e57 271 Gene3D G3DSA:2.70.70.10 132 265 2.0E-44 T 09-03-2017 UA74_RS27880 1506e8f84ddb92a51c0b1ccafbb94e57 271 Pfam PF01551 Peptidase family M23 164 260 5.8E-31 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS27880 1506e8f84ddb92a51c0b1ccafbb94e57 271 SUPERFAMILY SSF51261 136 264 4.03E-47 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS07275 478dbf83e117066a636fa61cf5891410 236 SUPERFAMILY SSF101473 9 205 4.71E-50 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS07275 478dbf83e117066a636fa61cf5891410 236 SMART SM01120 32 206 5.0E-69 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS07275 478dbf83e117066a636fa61cf5891410 236 Gene3D G3DSA:1.10.357.10 86 133 1.5E-4 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS07275 478dbf83e117066a636fa61cf5891410 236 Gene3D G3DSA:1.10.357.10 10 53 1.5E-4 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS07275 478dbf83e117066a636fa61cf5891410 236 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 14 205 4.5E-68 T 09-03-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 UA74_RS07275 478dbf83e117066a636fa61cf5891410 236 Pfam PF02734 DAK2 domain 32 205 2.9E-52 T 09-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS05185 6cf44939751a2e8a057bfc303be11cf8 269 SUPERFAMILY SSF75217 112 265 9.81E-36 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS05185 6cf44939751a2e8a057bfc303be11cf8 269 Pfam PF00588 SpoU rRNA Methylase family 119 260 1.6E-27 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_RS05185 6cf44939751a2e8a057bfc303be11cf8 269 Gene3D G3DSA:3.30.1330.30 8 105 1.7E-9 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS05185 6cf44939751a2e8a057bfc303be11cf8 269 SUPERFAMILY SSF55315 8 107 3.3E-7 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS05185 6cf44939751a2e8a057bfc303be11cf8 269 Gene3D G3DSA:3.40.1280.10 117 266 1.2E-36 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS06145 282beb3c9896f145d7d1c78975660e54 136 Gene3D G3DSA:3.40.50.1010 8 130 7.0E-15 T 09-03-2017 IPR029060 PIN domain-like UA74_RS06145 282beb3c9896f145d7d1c78975660e54 136 Pfam PF01850 PIN domain 10 122 1.4E-6 T 09-03-2017 IPR002716 PIN domain UA74_RS06145 282beb3c9896f145d7d1c78975660e54 136 SUPERFAMILY SSF88723 9 131 5.61E-17 T 09-03-2017 IPR029060 PIN domain-like UA74_RS06145 282beb3c9896f145d7d1c78975660e54 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 10 134 9.93 T 09-03-2017 IPR022907 VapC family GO:0004540 UA74_RS25740 6960d475ec7d590edfd91acb2d43ac91 218 Pfam PF02669 K+-transporting ATPase, c chain 11 205 1.2E-55 T 09-03-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 UA74_RS25740 6960d475ec7d590edfd91acb2d43ac91 218 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 6 208 29.941 T 09-03-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 UA74_RS25740 6960d475ec7d590edfd91acb2d43ac91 218 PIRSF PIRSF001296 5 212 1.6E-54 T 09-03-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 UA74_RS11335 666ac67205f23ad7c67cf7cf166a76cb 131 Gene3D G3DSA:1.10.10.10 4 105 1.8E-41 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11335 666ac67205f23ad7c67cf7cf166a76cb 131 SUPERFAMILY SSF46785 4 109 1.65E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11335 666ac67205f23ad7c67cf7cf166a76cb 131 Pfam PF01638 HxlR-like helix-turn-helix 8 92 2.1E-27 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS05155 54971d6258fb2358de9386003d6ab1a4 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 196 2.4E-39 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS05155 54971d6258fb2358de9386003d6ab1a4 217 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 09-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UA74_RS05155 54971d6258fb2358de9386003d6ab1a4 217 SUPERFAMILY SSF53254 1 215 3.8E-41 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS05155 54971d6258fb2358de9386003d6ab1a4 217 Gene3D G3DSA:3.40.50.1240 1 216 1.1E-42 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS05155 54971d6258fb2358de9386003d6ab1a4 217 SMART SM00855 5 161 6.2E-15 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS22670 1dd4259bad2d9d5267f8734ee2d4fb37 285 Pfam PF01381 Helix-turn-helix 10 59 3.8E-11 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS22670 1dd4259bad2d9d5267f8734ee2d4fb37 285 SUPERFAMILY SSF47413 4 61 5.09E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22670 1dd4259bad2d9d5267f8734ee2d4fb37 285 Gene3D G3DSA:1.10.260.40 2 59 4.3E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22670 1dd4259bad2d9d5267f8734ee2d4fb37 285 SMART SM00530 9 64 1.5E-10 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS22450 e71bcc6d2569843802e52e03fa19960a 323 Gene3D G3DSA:1.10.10.10 6 66 2.5E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22450 e71bcc6d2569843802e52e03fa19960a 323 PIRSF PIRSF016838 2 317 4.0E-24 T 09-03-2017 IPR028349 Protein PafC UA74_RS22450 e71bcc6d2569843802e52e03fa19960a 323 Pfam PF13280 WYL domain 141 309 3.5E-30 T 09-03-2017 IPR026881 WYL domain UA74_RS22450 e71bcc6d2569843802e52e03fa19960a 323 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS22450 e71bcc6d2569843802e52e03fa19960a 323 Pfam PF08279 HTH domain 7 62 4.7E-14 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS22450 e71bcc6d2569843802e52e03fa19960a 323 SUPERFAMILY SSF46785 5 62 2.59E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22450 e71bcc6d2569843802e52e03fa19960a 323 SMART SM00420 7 59 0.0072 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS22550 75cb6afeb52e376d159f8de32729170f 484 Gene3D G3DSA:1.25.40.10 7 210 2.8E-27 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22550 75cb6afeb52e376d159f8de32729170f 484 SUPERFAMILY SSF48452 71 224 1.57E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22550 75cb6afeb52e376d159f8de32729170f 484 SUPERFAMILY SSF48452 7 114 7.59E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS22550 75cb6afeb52e376d159f8de32729170f 484 Pfam PF14559 Tetratricopeptide repeat 47 90 1.4E-7 T 09-03-2017 UA74_RS22550 75cb6afeb52e376d159f8de32729170f 484 SMART SM00028 146 179 80.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS22550 75cb6afeb52e376d159f8de32729170f 484 SMART SM00028 2 35 30.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS22550 75cb6afeb52e376d159f8de32729170f 484 SMART SM00028 36 69 3.4 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS30470 e8fecbb344050c4995a72707c489b08a 45 Pfam PF00468 Ribosomal protein L34 3 45 1.3E-19 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30470 e8fecbb344050c4995a72707c489b08a 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 23 3.0E-5 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30470 e8fecbb344050c4995a72707c489b08a 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.739 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30470 e8fecbb344050c4995a72707c489b08a 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 4.1E-19 T 09-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS30470 e8fecbb344050c4995a72707c489b08a 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 09-03-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS17560 25a6c4403f15815b24be386542737e25 348 SUPERFAMILY SSF53335 120 342 2.71E-35 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17560 25a6c4403f15815b24be386542737e25 348 PIRSF PIRSF005739 3 348 1.8E-23 T 09-03-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_RS17560 25a6c4403f15815b24be386542737e25 348 SUPERFAMILY SSF46785 13 87 7.71E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17560 25a6c4403f15815b24be386542737e25 348 Gene3D G3DSA:1.10.10.10 18 89 1.6E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17560 25a6c4403f15815b24be386542737e25 348 Pfam PF00891 O-methyltransferase 137 332 5.9E-29 T 09-03-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_RS17560 25a6c4403f15815b24be386542737e25 348 Gene3D G3DSA:3.40.50.150 96 339 8.8E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17560 25a6c4403f15815b24be386542737e25 348 Pfam PF16864 Dimerisation domain 18 97 7.4E-8 T 09-03-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_RS24150 4f17c1c7275bf7b96efbc49a626f893a 294 Gene3D G3DSA:3.40.50.720 13 210 1.6E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24150 4f17c1c7275bf7b96efbc49a626f893a 294 SUPERFAMILY SSF51735 13 220 4.28E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24150 4f17c1c7275bf7b96efbc49a626f893a 294 Pfam PF00106 short chain dehydrogenase 15 150 4.8E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14290 4f38fc9fc26c9fb20c12ccf12c01f721 265 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 240 1.9E-63 T 09-03-2017 UA74_RS14290 4f38fc9fc26c9fb20c12ccf12c01f721 265 SUPERFAMILY SSF51621 7 259 6.73E-47 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS14290 4f38fc9fc26c9fb20c12ccf12c01f721 265 Gene3D G3DSA:3.20.20.60 3 222 5.0E-46 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 SMART SM01043 113 254 6.5E-39 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS01830 b91da1f1585692e15258ce86146607da 959 Gene3D G3DSA:1.25.40.10 757 956 3.2E-22 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 105 7.8E-8 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 SMART SM00862 27 106 3.1E-10 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 Pfam PF00931 NB-ARC domain 323 509 6.6E-7 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 Pfam PF13424 Tetratricopeptide repeat 827 894 5.1E-8 T 09-03-2017 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF52540 293 562 3.07E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01830 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF48452 110 274 9.1E-27 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 Pfam PF03704 Bacterial transcriptional activator domain 114 254 3.4E-37 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS01830 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF46894 14 106 5.95E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF48452 762 936 1.14E-22 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 PRINTS PR00364 Disease resistance protein signature 325 340 5.3E-7 T 09-03-2017 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 PRINTS PR00364 Disease resistance protein signature 408 422 5.3E-7 T 09-03-2017 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 PRINTS PR00364 Disease resistance protein signature 494 508 5.3E-7 T 09-03-2017 UA74_RS01830 b91da1f1585692e15258ce86146607da 959 Gene3D G3DSA:1.10.10.10 21 109 6.9E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11105 ebfbf9cd561584285b6cfde4e3d5835f 116 SUPERFAMILY SSF54909 7 97 2.23E-18 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS11105 ebfbf9cd561584285b6cfde4e3d5835f 116 Gene3D G3DSA:3.30.70.900 7 99 5.0E-12 T 09-03-2017 UA74_RS11105 ebfbf9cd561584285b6cfde4e3d5835f 116 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 78 1.4E-8 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS21290 1e95a3d578e76a0ac4d62cf817ab9082 240 Gene3D G3DSA:3.40.50.1820 16 212 9.2E-21 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21290 1e95a3d578e76a0ac4d62cf817ab9082 240 Pfam PF12697 Alpha/beta hydrolase family 30 219 4.1E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS21290 1e95a3d578e76a0ac4d62cf817ab9082 240 SUPERFAMILY SSF53474 10 211 9.76E-24 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27000 a6809b485f466de1d3f30a5e3c0c33ee 184 Pfam PF04138 GtrA-like protein 27 157 3.4E-22 T 09-03-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 UA74_RS10775 2b415581d3afe352e02b99eaad3e3895 312 Pfam PF12679 ABC-2 family transporter protein 58 310 1.8E-14 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 UA74_RS27705 7ac5f721021bbb91f32a71ff0f8ed760 363 Pfam PF03631 Virulence factor BrkB 45 301 6.3E-43 T 09-03-2017 IPR017039 Virulence factor BrkB UA74_RS27705 7ac5f721021bbb91f32a71ff0f8ed760 363 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 34 300 3.6E-69 T 09-03-2017 IPR005274 Inner membrane protein YhjD UA74_RS22745 ce7e762199a0235c932371c26543bdc9 306 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 305 6.0E-24 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS22745 ce7e762199a0235c932371c26543bdc9 306 Gene3D G3DSA:3.40.50.300 2 254 6.0E-81 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22745 ce7e762199a0235c932371c26543bdc9 306 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 299 2.7E-19 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS22745 ce7e762199a0235c932371c26543bdc9 306 Pfam PF00005 ABC transporter 26 179 2.8E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS22745 ce7e762199a0235c932371c26543bdc9 306 SUPERFAMILY SSF52540 2 250 2.83E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22745 ce7e762199a0235c932371c26543bdc9 306 SMART SM00382 35 229 1.3E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22745 ce7e762199a0235c932371c26543bdc9 306 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS19365 0b4b065a5e4b134f81dc74402560095d 189 SUPERFAMILY SSF46689 1 71 8.48E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS19365 0b4b065a5e4b134f81dc74402560095d 189 Gene3D G3DSA:1.10.357.10 3 181 8.1E-23 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS19365 0b4b065a5e4b134f81dc74402560095d 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 2.3E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.3E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.3E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.3E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 192 0.004 T 09-03-2017 UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 252 1.1E-59 T 09-03-2017 UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 Gene3D G3DSA:3.40.50.720 9 253 1.8E-80 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.9E-43 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13600 b577fd7401d9e78c17c8ab9afe318800 254 SUPERFAMILY SSF51735 13 253 2.58E-77 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23190 96b0fef5f7d94fd7a07ed0369ecd11ab 72 Pfam PF13275 S4 domain 4 67 2.7E-24 T 09-03-2017 UA74_RS23190 96b0fef5f7d94fd7a07ed0369ecd11ab 72 SUPERFAMILY SSF55174 2 66 6.41E-18 T 09-03-2017 UA74_RS23190 96b0fef5f7d94fd7a07ed0369ecd11ab 72 Gene3D G3DSA:3.10.290.10 1 67 3.7E-25 T 09-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 UA74_RS12230 e8fc4a59f998aef238a802b9dd20201e 369 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 338 3.6E-108 T 09-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_RS12230 e8fc4a59f998aef238a802b9dd20201e 369 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 5 355 37.547 T 09-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_RS12230 e8fc4a59f998aef238a802b9dd20201e 369 Gene3D G3DSA:3.40.50.1970 11 170 5.8E-54 T 09-03-2017 UA74_RS12230 e8fc4a59f998aef238a802b9dd20201e 369 PIRSF PIRSF001455 4 351 1.1E-99 T 09-03-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_RS12230 e8fc4a59f998aef238a802b9dd20201e 369 Gene3D G3DSA:1.20.1090.10 172 353 1.4E-61 T 09-03-2017 UA74_RS12230 e8fc4a59f998aef238a802b9dd20201e 369 SUPERFAMILY SSF56796 10 353 1.01E-101 T 09-03-2017 UA74_RS12230 e8fc4a59f998aef238a802b9dd20201e 369 Pfam PF01761 3-dehydroquinate synthase 66 322 1.9E-93 T 09-03-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_RS17645 6bf3630254ea6e9cb52791b867b18fbc 535 Pfam PF00221 Aromatic amino acid lyase 17 495 6.1E-163 T 09-03-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 UA74_RS17645 6bf3630254ea6e9cb52791b867b18fbc 535 SUPERFAMILY SSF48557 8 524 6.67E-169 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 UA74_RS17645 6bf3630254ea6e9cb52791b867b18fbc 535 Gene3D G3DSA:1.10.275.10 4 203 7.3E-63 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal UA74_RS17645 6bf3630254ea6e9cb52791b867b18fbc 535 TIGRFAM TIGR03832 Tyr_2_3_mutase: tyrosine 2,3-aminomutase 12 518 2.0E-287 T 09-03-2017 IPR022314 Tyrosine 2,3-aminomutase, putative KEGG: 00350+5.4.3.6+4.3.1.23 UA74_RS17645 6bf3630254ea6e9cb52791b867b18fbc 535 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 09-03-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 UA74_RS17645 6bf3630254ea6e9cb52791b867b18fbc 535 Gene3D G3DSA:1.20.200.10 204 531 1.8E-109 T 09-03-2017 UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 145 162 3.0E-19 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 164 187 3.0E-19 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 124 144 3.0E-19 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 65 79 3.0E-19 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 188 202 3.0E-19 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 SUPERFAMILY SSF50494 44 213 3.39E-26 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 Gene3D G3DSA:2.40.10.10 118 211 4.5E-19 T 09-03-2017 UA74_RS01925 11bc50af06ed805c47261def5cdb1b5c 220 Gene3D G3DSA:2.40.10.10 44 117 1.8E-21 T 09-03-2017 UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 Gene3D G3DSA:3.40.50.300 16 170 1.4E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 20 322 1.6E-133 T 09-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 SMART SM00382 47 180 1.2E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 249 324 4.0E-30 T 09-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 SUPERFAMILY SSF52540 16 247 1.04E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 342 156.725 T 09-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 249 322 2.9E-28 T 09-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 Gene3D G3DSA:1.10.8.60 179 251 6.1E-32 T 09-03-2017 UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 3 231 3.5E-105 T 09-03-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 SUPERFAMILY SSF46785 252 326 7.89E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11160 6d1af7a10718e1af3aa0a5a5e6f8b4f2 342 Gene3D G3DSA:1.10.10.10 253 323 1.0E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17585 80622057feb7da938ef2213350af6a43 513 Gene3D G3DSA:1.20.1250.20 478 504 7.9E-12 T 09-03-2017 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 Gene3D G3DSA:1.20.1250.20 263 425 7.9E-12 T 09-03-2017 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 Gene3D G3DSA:1.20.1250.20 14 196 3.9E-26 T 09-03-2017 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 Pfam PF07690 Major Facilitator Superfamily 27 414 1.0E-36 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 SUPERFAMILY SSF103473 477 505 4.32E-20 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS17585 80622057feb7da938ef2213350af6a43 513 SUPERFAMILY SSF103473 213 424 4.32E-20 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS17585 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 82 104 6.8E-5 T 09-03-2017 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 6.8E-5 T 09-03-2017 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 6.8E-5 T 09-03-2017 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 6.8E-5 T 09-03-2017 UA74_RS17585 80622057feb7da938ef2213350af6a43 513 SUPERFAMILY SSF103473 8 200 1.07E-37 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS02000 1cc82a197183cd89ffbdeccf3607b359 118 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 110 6.4E-19 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_RS02000 1cc82a197183cd89ffbdeccf3607b359 118 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 115 15.548 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_RS23270 c5fdf2c00a7db647431eac6dc6035ef2 272 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 167 256 1.0E-15 T 09-03-2017 IPR013382 CRISPR-associated protein Cse2 UA74_RS23270 c5fdf2c00a7db647431eac6dc6035ef2 272 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 174 258 6.6E-12 T 09-03-2017 IPR013382 CRISPR-associated protein Cse2 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 Gene3D G3DSA:3.20.20.70 4 300 1.4E-76 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 PIRSF PIRSF001365 3 304 5.5E-66 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 SMART SM01130 7 299 4.5E-82 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 2.2E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 2.2E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 2.2E-6 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 SUPERFAMILY SSF51569 4 297 7.01E-74 T 09-03-2017 UA74_RS17035 32b3f99735970a2879636e0d9df055c5 305 Pfam PF00701 Dihydrodipicolinate synthetase family 8 294 1.7E-43 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS15460 56c3b20225fae24491c59d9d26fa4378 131 Pfam PF04542 Sigma-70 region 2 5 69 3.9E-9 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15460 56c3b20225fae24491c59d9d26fa4378 131 Gene3D G3DSA:1.10.10.10 93 130 3.2E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15460 56c3b20225fae24491c59d9d26fa4378 131 SUPERFAMILY SSF88946 4 67 3.65E-11 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS15460 56c3b20225fae24491c59d9d26fa4378 131 Gene3D G3DSA:1.10.1740.10 4 92 2.9E-12 T 09-03-2017 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 Pfam PF03454 MoeA C-terminal region (domain IV) 347 411 3.0E-14 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 Gene3D G3DSA:3.40.980.10 175 343 9.9E-56 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 Gene3D G3DSA:3.90.105.10 144 174 1.1E-15 T 09-03-2017 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 SUPERFAMILY SSF53218 189 332 4.45E-40 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 SUPERFAMILY SSF63882 14 188 3.14E-48 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 Pfam PF03453 MoeA N-terminal region (domain I and II) 19 179 2.4E-32 T 09-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 Gene3D G3DSA:2.40.340.10 347 409 1.0E-15 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 SUPERFAMILY SSF63867 346 412 7.19E-15 T 09-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 189 324 7.8E-32 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 Pfam PF00994 Probable molybdopterin binding domain 193 326 1.9E-24 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 Gene3D G3DSA:2.170.190.11 57 143 4.1E-30 T 09-03-2017 UA74_RS28730 187b2735d1ab16030eb7e3ed7d538d7b 425 SMART SM00852 192 328 4.5E-40 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS15690 d68cae6dbe541db06745b9629503468f 159 SUPERFAMILY SSF46785 19 147 6.39E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15690 d68cae6dbe541db06745b9629503468f 159 SMART SM00347 38 140 2.2E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS15690 d68cae6dbe541db06745b9629503468f 159 Gene3D G3DSA:1.10.10.10 14 146 2.7E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15690 d68cae6dbe541db06745b9629503468f 159 Pfam PF12802 MarR family 46 102 7.6E-8 T 09-03-2017 UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 186 0.002 T 09-03-2017 UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.9E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.9E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.9E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.9E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.9E-33 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 256 2.1E-59 T 09-03-2017 UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 Gene3D G3DSA:3.40.50.720 8 258 3.5E-80 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15175 2f067411e847cd28fc7d35bdda8fdf8a 263 SUPERFAMILY SSF51735 13 257 1.05E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14355 3e6764387fb35f88da9dbe043add7566 255 Gene3D G3DSA:3.40.630.30 124 215 8.0E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14355 3e6764387fb35f88da9dbe043add7566 255 SUPERFAMILY SSF55729 53 211 2.98E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14355 3e6764387fb35f88da9dbe043add7566 255 Pfam PF08445 FR47-like protein 160 212 6.6E-7 T 09-03-2017 IPR013653 FR47-like GO:0016747 UA74_RS12455 9e0da9e445e1b996154ec75bd8e3fd10 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 7.0E-6 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_RS12455 9e0da9e445e1b996154ec75bd8e3fd10 78 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 7.0E-6 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_RS12455 9e0da9e445e1b996154ec75bd8e3fd10 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 7.0E-6 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_RS12455 9e0da9e445e1b996154ec75bd8e3fd10 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 4.3E-20 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_RS12455 9e0da9e445e1b996154ec75bd8e3fd10 78 Pfam PF03840 Preprotein translocase SecG subunit 4 72 2.7E-18 T 09-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 Pfam PF00571 CBS domain 100 136 0.0025 T 09-03-2017 IPR000644 CBS domain UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 SUPERFAMILY SSF51412 203 473 3.53E-91 T 09-03-2017 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 SUPERFAMILY SSF51412 11 93 3.53E-91 T 09-03-2017 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 474 6.1E-104 T 09-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 SMART SM01240 11 475 6.0E-189 T 09-03-2017 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 SUPERFAMILY SSF54631 99 202 4.42E-15 T 09-03-2017 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 Gene3D G3DSA:3.20.20.70 11 475 1.4E-126 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 PIRSF PIRSF000130 3 479 1.2E-139 T 09-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_RS04105 37af19ab889c95c867bb336853ed2d62 479 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 477 5.1E-247 T 09-03-2017 IPR005991 IMP dehydrogenase-related 1 UA74_RS11270 1a8b1be0bdd2d824074323280ff786ba 509 Gene3D G3DSA:3.40.630.30 356 481 1.3E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS11270 1a8b1be0bdd2d824074323280ff786ba 509 Gene3D G3DSA:3.30.70.260 173 210 2.3E-5 T 09-03-2017 UA74_RS11270 1a8b1be0bdd2d824074323280ff786ba 509 SUPERFAMILY SSF55021 172 236 1.22E-7 T 09-03-2017 UA74_RS11270 1a8b1be0bdd2d824074323280ff786ba 509 SUPERFAMILY SSF55729 344 481 9.76E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS11270 1a8b1be0bdd2d824074323280ff786ba 509 Pfam PF01842 ACT domain 173 219 1.9E-6 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 UA74_RS11270 1a8b1be0bdd2d824074323280ff786ba 509 Pfam PF00583 Acetyltransferase (GNAT) family 415 477 1.2E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS18965 0ff647f4f5a6388bf71e174d7c6c0bf0 428 SUPERFAMILY SSF53850 21 419 3.86E-58 T 09-03-2017 UA74_RS18965 0ff647f4f5a6388bf71e174d7c6c0bf0 428 Gene3D G3DSA:3.40.190.10 162 358 4.9E-32 T 09-03-2017 UA74_RS18965 0ff647f4f5a6388bf71e174d7c6c0bf0 428 Gene3D G3DSA:3.40.190.10 35 161 5.7E-11 T 09-03-2017 UA74_RS18965 0ff647f4f5a6388bf71e174d7c6c0bf0 428 Pfam PF13416 Bacterial extracellular solute-binding protein 51 363 1.2E-23 T 09-03-2017 UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 PIRSF PIRSF004749 1 178 1.5E-43 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 128 157 5.0E-32 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 33 62 5.0E-32 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 97 108 5.0E-32 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 109 127 5.0E-32 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 Gene3D G3DSA:3.90.45.10 5 188 3.7E-60 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 Pfam PF01327 Polypeptide deformylase 4 158 2.8E-43 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 SUPERFAMILY SSF56420 1 164 7.2E-54 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 10 164 2.5E-38 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS01870 c37b593a6d05bef258fce3ed1f3ab9cd 193 Hamap MF_00163 Peptide deformylase [def]. 2 170 28.36 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS08260 e706c63f1ab563ca1e7569f489a151c4 189 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 15 189 27.477 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_RS08260 e706c63f1ab563ca1e7569f489a151c4 189 Gene3D G3DSA:3.90.79.10 8 180 4.0E-45 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS08260 e706c63f1ab563ca1e7569f489a151c4 189 SUPERFAMILY SSF55811 17 179 1.02E-38 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS08260 e706c63f1ab563ca1e7569f489a151c4 189 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 19 177 2.2E-34 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_RS08260 e706c63f1ab563ca1e7569f489a151c4 189 Pfam PF00293 NUDIX domain 42 175 9.4E-24 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS08260 e706c63f1ab563ca1e7569f489a151c4 189 PIRSF PIRSF018427 1 188 8.1E-47 T 09-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_RS01335 f520224c7279b7a4f825d5222b446968 425 Pfam PF00144 Beta-lactamase 78 410 2.6E-72 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS01335 f520224c7279b7a4f825d5222b446968 425 Gene3D G3DSA:3.40.710.10 62 404 2.7E-83 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS01335 f520224c7279b7a4f825d5222b446968 425 SUPERFAMILY SSF56601 74 412 3.24E-85 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS03920 c09af71db68821d831ba933803027038 384 Gene3D G3DSA:3.30.390.10 9 116 3.9E-37 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03920 c09af71db68821d831ba933803027038 384 SMART SM00922 132 237 2.1E-21 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS03920 c09af71db68821d831ba933803027038 384 Gene3D G3DSA:3.20.20.120 117 355 6.8E-88 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS03920 c09af71db68821d831ba933803027038 384 SUPERFAMILY SSF54826 3 116 1.85E-26 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS03920 c09af71db68821d831ba933803027038 384 Pfam PF13378 Enolase C-terminal domain-like 137 358 1.5E-65 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS03920 c09af71db68821d831ba933803027038 384 SUPERFAMILY SSF51604 99 365 9.04E-81 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS03920 c09af71db68821d831ba933803027038 384 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 111 9.0E-14 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 Gene3D G3DSA:3.30.70.240 134 205 1.5E-11 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 09-03-2017 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 Pfam PF01205 Uncharacterized protein family UPF0029 19 123 2.8E-29 T 09-03-2017 IPR001498 Impact, N-terminal UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 SUPERFAMILY SSF54980 135 200 2.16E-9 T 09-03-2017 IPR009022 Elongation factor G, III-V domain UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 SUPERFAMILY SSF54211 3 131 4.55E-42 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 1.2E-10 T 09-03-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 Gene3D G3DSA:3.30.230.30 5 131 4.2E-47 T 09-03-2017 IPR001498 Impact, N-terminal UA74_RS14770 8bc25e6ce506c8d6b3e1f5818acaf246 210 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 202 1.5E-57 T 09-03-2017 IPR015796 Impact family, bacterial/archaeal UA74_RS07560 c5b47a3548b12cc58dcbebb055e0d9db 288 SUPERFAMILY SSF55729 119 282 4.33E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS07560 c5b47a3548b12cc58dcbebb055e0d9db 288 Pfam PF00583 Acetyltransferase (GNAT) family 202 276 1.8E-6 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS07560 c5b47a3548b12cc58dcbebb055e0d9db 288 Gene3D G3DSA:3.40.630.30 149 282 8.0E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS06140 3bca0c19568ac87679f55137a73b453a 60 Gene3D G3DSA:3.20.20.140 1 59 1.3E-11 T 09-03-2017 UA74_RS06140 3bca0c19568ac87679f55137a73b453a 60 Pfam PF00962 Adenosine/AMP deaminase 3 58 2.3E-11 T 09-03-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 UA74_RS06140 3bca0c19568ac87679f55137a73b453a 60 SUPERFAMILY SSF51556 1 58 3.3E-12 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 Gene3D G3DSA:2.120.10.30 9 120 7.3E-56 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 Gene3D G3DSA:2.120.10.30 152 307 7.3E-56 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 19 287 1.1E-51 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 SUPERFAMILY SSF63829 15 119 2.13E-41 T 09-03-2017 UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 SUPERFAMILY SSF63829 151 305 2.13E-41 T 09-03-2017 UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 268 286 3.8E-17 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 226 243 3.8E-17 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 18 35 3.8E-17 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS06320 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 186 206 3.8E-17 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 SUPERFAMILY SSF54806 134 191 1.05E-5 T 09-03-2017 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 PIRSF PIRSF001134 2 385 2.2E-123 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:2.40.10.10 202 280 1.8E-24 T 09-03-2017 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:2.40.10.10 281 370 1.2E-28 T 09-03-2017 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 Pfam PF00089 Trypsin 202 374 1.1E-8 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:3.30.300.50 45 125 4.9E-26 T 09-03-2017 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 SUPERFAMILY SSF50494 203 379 4.24E-34 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 Pfam PF02983 Alpha-lytic protease prodomain 128 183 1.7E-12 T 09-03-2017 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:3.30.300.50 127 195 2.5E-15 T 09-03-2017 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 238 6.7E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 324 347 6.7E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 348 362 6.7E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 284 304 6.7E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01935 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 305 322 6.7E-40 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS11795 6f052701376013f965efa41384751bab 215 SUPERFAMILY SSF56784 13 178 6.54E-42 T 09-03-2017 IPR023214 HAD-like domain UA74_RS11795 6f052701376013f965efa41384751bab 215 Gene3D G3DSA:3.40.50.1000 11 181 2.6E-47 T 09-03-2017 IPR023214 HAD-like domain UA74_RS11795 6f052701376013f965efa41384751bab 215 Pfam PF13242 HAD-hyrolase-like 112 176 2.2E-12 T 09-03-2017 UA74_RS11795 6f052701376013f965efa41384751bab 215 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 18 157 1.1E-30 T 09-03-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 UA74_RS11795 6f052701376013f965efa41384751bab 215 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 18 158 1.9E-32 T 09-03-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 UA74_RS15480 ad29e71f06e554c706c41b3610065df9 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 3.3E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15480 ad29e71f06e554c706c41b3610065df9 209 Gene3D G3DSA:1.10.10.60 3 67 2.2E-22 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15480 ad29e71f06e554c706c41b3610065df9 209 SUPERFAMILY SSF48498 83 196 2.31E-29 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS15480 ad29e71f06e554c706c41b3610065df9 209 Gene3D G3DSA:1.10.357.10 70 197 4.9E-42 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15480 ad29e71f06e554c706c41b3610065df9 209 SUPERFAMILY SSF46689 2 79 1.59E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SUPERFAMILY SSF48452 821 921 1.78E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Gene3D G3DSA:1.25.40.10 690 829 4.5E-22 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Gene3D G3DSA:1.25.40.10 830 920 2.6E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Gene3D G3DSA:1.10.10.10 10 93 1.6E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Gene3D G3DSA:1.25.40.10 108 220 1.5E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SUPERFAMILY SSF48452 691 849 5.56E-20 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM00028 103 136 78.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM00028 843 876 290.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM00028 803 836 8.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM00028 723 756 0.0099 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM00028 763 796 55.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM00028 883 916 39.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 PRINTS PR00364 Disease resistance protein signature 384 398 1.3E-9 T 09-03-2017 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 PRINTS PR00364 Disease resistance protein signature 303 318 1.3E-9 T 09-03-2017 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 PRINTS PR00364 Disease resistance protein signature 469 483 1.3E-9 T 09-03-2017 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SUPERFAMILY SSF46894 2 91 2.41E-11 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SUPERFAMILY SSF48452 93 254 4.77E-35 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SUPERFAMILY SSF52540 268 537 1.51E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM00862 15 91 4.8E-7 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Gene3D G3DSA:3.40.50.300 275 328 6.6E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Pfam PF03704 Bacterial transcriptional activator domain 98 243 2.6E-39 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 91 1.9E-6 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Pfam PF00931 NB-ARC domain 301 534 3.4E-13 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Pfam PF13424 Tetratricopeptide repeat 763 830 8.9E-10 T 09-03-2017 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 Pfam PF13424 Tetratricopeptide repeat 845 914 2.0E-8 T 09-03-2017 UA74_RS18415 3639db440b89738d9703ec15919acbe6 945 SMART SM01043 98 243 3.0E-47 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.3E-19 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 3.3E-19 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.3E-19 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 3.3E-19 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.3E-19 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 Gene3D G3DSA:3.50.50.60 9 163 7.2E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 SUPERFAMILY SSF51905 9 196 3.08E-39 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 Gene3D G3DSA:3.30.390.30 328 400 4.3E-17 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 Gene3D G3DSA:3.50.50.60 164 320 1.7E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 SUPERFAMILY SSF51905 149 317 2.04E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 Pfam PF14759 Reductase C-terminal 328 396 5.9E-12 T 09-03-2017 IPR028202 Reductase, C-terminal UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.1E-15 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 6.1E-15 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 6.1E-15 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 6.1E-15 T 09-03-2017 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 SUPERFAMILY SSF55424 321 397 2.33E-19 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS07770 a6c3c842612f8339fffe14f6477f7412 404 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 308 7.9E-53 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS05710 901a564154dbd22728222e00b79d0624 193 Gene3D G3DSA:3.50.30.40 10 166 1.5E-47 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein UA74_RS05710 901a564154dbd22728222e00b79d0624 193 Pfam PF03737 Demethylmenaquinone methyltransferase 13 158 1.9E-41 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein UA74_RS05710 901a564154dbd22728222e00b79d0624 193 SUPERFAMILY SSF89562 9 169 7.06E-42 T 09-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein UA74_RS26930 8db21f196abb4c86d3070d4eb2029fa5 661 Pfam PF14517 Tachylectin 119 212 3.5E-13 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS26930 8db21f196abb4c86d3070d4eb2029fa5 661 SUPERFAMILY SSF50934 135 306 2.22E-13 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS26930 8db21f196abb4c86d3070d4eb2029fa5 661 SUPERFAMILY SSF89372 501 621 7.06E-7 T 09-03-2017 UA74_RS26930 8db21f196abb4c86d3070d4eb2029fa5 661 Gene3D G3DSA:2.115.10.10 137 294 3.6E-20 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS26930 8db21f196abb4c86d3070d4eb2029fa5 661 SUPERFAMILY SSF89372 273 523 7.59E-14 T 09-03-2017 UA74_RS29860 d19e24c9974616cd0bff332073eebe76 578 Pfam PF04294 VanW like protein 366 496 9.5E-39 T 09-03-2017 IPR007391 Vancomycin resistance VanW UA74_RS29860 d19e24c9974616cd0bff332073eebe76 578 Pfam PF12229 Putative peptidoglycan binding domain 220 318 1.1E-10 T 09-03-2017 IPR022029 Putative peptidoglycan binding domain UA74_RS27810 92c480d806829af6d17ff49234e9be03 200 SUPERFAMILY SSF141571 21 198 3.92E-44 T 09-03-2017 UA74_RS27810 92c480d806829af6d17ff49234e9be03 200 Pfam PF13599 Pentapeptide repeats (9 copies) 30 104 1.3E-9 T 09-03-2017 IPR001646 Pentapeptide repeat UA74_RS27810 92c480d806829af6d17ff49234e9be03 200 Pfam PF00805 Pentapeptide repeats (8 copies) 130 166 3.6E-12 T 09-03-2017 IPR001646 Pentapeptide repeat UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 Pfam PF00919 Uncharacterized protein family UPF0004 9 106 1.3E-26 T 09-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 8 445 8.2E-146 T 09-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 153 173 - T 09-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 Pfam PF04055 Radical SAM superfamily 153 324 6.8E-30 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 8 417 7.5E-139 T 09-03-2017 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 SMART SM00729 149 367 8.1E-59 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 6 450 66.466 T 09-03-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 SUPERFAMILY SSF102114 135 374 3.79E-60 T 09-03-2017 UA74_RS08690 e65433ecad8921322d9e0e2a82b096ba 496 Gene3D G3DSA:3.80.30.20 149 378 3.3E-83 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe UA74_RS16705 f5b68a13f6a13343e8dadcfbc5f27d28 484 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 86 8.2E-30 T 09-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 UA74_RS16705 f5b68a13f6a13343e8dadcfbc5f27d28 484 SUPERFAMILY SSF52794 3 98 7.67E-31 T 09-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UA74_RS16705 f5b68a13f6a13343e8dadcfbc5f27d28 484 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 86 1.9E-18 T 09-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UA74_RS16705 f5b68a13f6a13343e8dadcfbc5f27d28 484 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 128 462 1.3E-104 T 09-03-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 UA74_RS16705 f5b68a13f6a13343e8dadcfbc5f27d28 484 Gene3D G3DSA:3.40.50.2300 1 101 7.3E-37 T 09-03-2017 UA74_RS25465 f56a16a721e78b6a489bc1cd92ee9e75 176 Gene3D G3DSA:3.40.390.10 56 149 9.5E-7 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 UA74_RS25465 f56a16a721e78b6a489bc1cd92ee9e75 176 Pfam PF11350 Protein of unknown function (DUF3152) 6 167 1.0E-47 T 09-03-2017 IPR022603 Domain of unknown function DUF3152 UA74_RS25465 f56a16a721e78b6a489bc1cd92ee9e75 176 SUPERFAMILY SSF55486 27 163 1.81E-19 T 09-03-2017 UA74_RS10985 e2e96a8dccd62f87fe73b1fb5130f37f 343 SUPERFAMILY SSF46785 15 94 4.08E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10985 e2e96a8dccd62f87fe73b1fb5130f37f 343 SUPERFAMILY SSF53335 96 334 3.52E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10985 e2e96a8dccd62f87fe73b1fb5130f37f 343 Pfam PF16864 Dimerisation domain 17 95 2.1E-13 T 09-03-2017 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_RS10985 e2e96a8dccd62f87fe73b1fb5130f37f 343 Gene3D G3DSA:3.40.50.150 99 335 2.2E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10985 e2e96a8dccd62f87fe73b1fb5130f37f 343 Pfam PF00891 O-methyltransferase 104 325 6.7E-32 T 09-03-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_RS10985 e2e96a8dccd62f87fe73b1fb5130f37f 343 Gene3D G3DSA:1.10.10.10 10 89 2.6E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF55729 30 172 1.46E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.50.720 195 333 1.1E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF52210 496 642 9.29E-20 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF00583 Acetyltransferase (GNAT) family 92 166 1.7E-9 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.30.470.20 711 796 4.8E-5 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF52210 334 493 7.06E-36 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 357 489 9.3E-44 T 09-03-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF56059 708 910 9.06E-21 T 09-03-2017 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.50.261 487 593 2.4E-9 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF51735 203 339 1.18E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.630.30 26 179 8.5E-24 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF13549 ATP-grasp domain 705 910 3.2E-52 T 09-03-2017 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 SMART SM00881 208 303 1.5E-35 T 09-03-2017 IPR003781 CoA-binding GO:0048037 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.50.261 334 486 1.9E-32 T 09-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_RS08850 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF13380 CoA binding domain 212 338 1.0E-24 T 09-03-2017 IPR003781 CoA-binding GO:0048037 UA74_RS04400 8c8734e468e3583ad6603d619d18f532 571 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 429 2.7E-35 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS04400 8c8734e468e3583ad6603d619d18f532 571 Gene3D G3DSA:3.90.76.10 45 194 4.6E-16 T 09-03-2017 UA74_RS04400 8c8734e468e3583ad6603d619d18f532 571 SUPERFAMILY SSF53850 33 565 4.16E-60 T 09-03-2017 UA74_RS04400 8c8734e468e3583ad6603d619d18f532 571 Gene3D G3DSA:3.40.190.10 195 300 2.4E-14 T 09-03-2017 UA74_RS04400 8c8734e468e3583ad6603d619d18f532 571 Gene3D G3DSA:3.10.105.10 301 536 5.1E-20 T 09-03-2017 UA74_RS14810 be9a34f2c0396688619aebee57f34d9d 553 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 27 520 15.383 T 09-03-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UA74_RS14810 be9a34f2c0396688619aebee57f34d9d 553 SUPERFAMILY SSF56317 242 512 3.92E-42 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS14810 be9a34f2c0396688619aebee57f34d9d 553 Gene3D G3DSA:3.60.110.10 239 512 5.1E-35 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS14810 be9a34f2c0396688619aebee57f34d9d 553 Pfam PF00795 Carbon-nitrogen hydrolase 317 506 4.4E-18 T 09-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 UA74_RS14810 be9a34f2c0396688619aebee57f34d9d 553 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 74 482 2.5E-73 T 09-03-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UA74_RS12845 4c1b7a52b040fcda48153e0486121fcb 322 Pfam PF00348 Polyprenyl synthetase 17 253 1.7E-51 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS12845 4c1b7a52b040fcda48153e0486121fcb 322 Gene3D G3DSA:1.10.600.10 12 302 6.8E-70 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS12845 4c1b7a52b040fcda48153e0486121fcb 322 SUPERFAMILY SSF48576 10 300 1.6E-66 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS12845 4c1b7a52b040fcda48153e0486121fcb 322 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 188 200 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 SMART SM00345 30 86 9.5E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 SMART SM00866 105 243 2.0E-39 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 Gene3D G3DSA:1.10.10.10 21 82 1.5E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 SUPERFAMILY SSF46785 25 94 1.23E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 SUPERFAMILY SSF64288 74 247 8.17E-46 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 Pfam PF07702 UTRA domain 107 243 6.4E-35 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 Gene3D G3DSA:3.40.1410.10 83 248 3.2E-47 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 2.2E-11 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 2.2E-11 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS12190 c966cc9b83945adc0f3fa919ab3c4dd4 267 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 85 2.0E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS07615 87864baa37573efc284b044a195febce 477 Pfam PF01636 Phosphotransferase enzyme family 148 381 4.4E-5 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS07615 87864baa37573efc284b044a195febce 477 Gene3D G3DSA:3.90.1200.10 272 440 4.4E-4 T 09-03-2017 UA74_RS07615 87864baa37573efc284b044a195febce 477 SUPERFAMILY SSF56112 408 436 6.73E-16 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS07615 87864baa37573efc284b044a195febce 477 SUPERFAMILY SSF56112 149 381 6.73E-16 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 Pfam PF00106 short chain dehydrogenase 12 194 4.7E-49 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.1E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.1E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.1E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.1E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.1E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.1E-32 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.0E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.0E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.0E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 SUPERFAMILY SSF51735 7 251 3.24E-66 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 Gene3D G3DSA:3.40.50.720 7 252 6.4E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09205 ab281e36b07923d146e9a4c11a372682 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 189 8.5E-5 T 09-03-2017 UA74_RS18710 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Pfam PF05199 GMC oxidoreductase 451 509 2.0E-15 T 09-03-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 UA74_RS18710 f5df5d7d94eeaa782d32b7f8e76dcc58 563 SUPERFAMILY SSF51905 454 515 1.3E-49 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18710 f5df5d7d94eeaa782d32b7f8e76dcc58 563 SUPERFAMILY SSF51905 4 276 1.3E-49 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18710 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Gene3D G3DSA:3.50.50.60 421 515 7.0E-69 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18710 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Gene3D G3DSA:3.50.50.60 5 124 7.0E-69 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18710 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Gene3D G3DSA:3.50.50.60 172 278 7.0E-69 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18710 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Pfam PF00732 GMC oxidoreductase 8 258 2.1E-16 T 09-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 Gene3D G3DSA:3.40.50.1700 405 656 6.2E-61 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 SMART SM01217 720 789 8.7E-27 T 09-03-2017 IPR026891 Fibronectin type III-like domain UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 115 131 3.7E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 184 200 3.7E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 286 304 3.7E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 215 231 3.7E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 PRINTS PR00133 Glycosyl hydrolase family 3 signature 138 157 3.7E-20 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 Gene3D G3DSA:3.20.20.300 17 379 4.9E-102 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 Pfam PF14310 Fibronectin type III-like domain 720 789 6.2E-19 T 09-03-2017 IPR026891 Fibronectin type III-like domain UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 420 657 6.8E-46 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 38 366 1.1E-70 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 SUPERFAMILY SSF52279 420 660 4.32E-47 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS18970 cd013c4e5591bccc532b03ec60e48313 828 SUPERFAMILY SSF51445 17 419 3.16E-96 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS13180 054bf498abf5f83a214845203d88ad8c 406 SUPERFAMILY SSF56059 115 310 5.83E-23 T 09-03-2017 UA74_RS13180 054bf498abf5f83a214845203d88ad8c 406 Gene3D G3DSA:3.30.470.20 106 304 1.7E-17 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS27135 588cb218aedd838737f7ef70fcbb8444 403 Pfam PF04235 Protein of unknown function (DUF418) 279 390 1.9E-6 T 09-03-2017 IPR007349 Domain of unknown function DUF418 UA74_RS27135 588cb218aedd838737f7ef70fcbb8444 403 Pfam PF07786 Protein of unknown function (DUF1624) 8 218 3.0E-5 T 09-03-2017 IPR012429 Protein of unknown function DUF1624 KEGG: 00531+2.3.1.78|Reactome: R-HSA-2024096|Reactome: R-HSA-2206291 UA74_RS06630 335f7f3c08d1bcae0beb7863d4635115 68 Pfam PF04149 Domain of unknown function (DUF397) 10 63 2.1E-19 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS08465 5f13cca0e7e00b533ab2e7c8df7d63a5 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS08465 5f13cca0e7e00b533ab2e7c8df7d63a5 307 SUPERFAMILY SSF53613 5 300 3.59E-66 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS08465 5f13cca0e7e00b533ab2e7c8df7d63a5 307 Pfam PF00294 pfkB family carbohydrate kinase 6 300 1.9E-54 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS08465 5f13cca0e7e00b533ab2e7c8df7d63a5 307 Gene3D G3DSA:3.40.1190.20 3 299 8.3E-68 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS00940 46572034fdb105726bc2e30c6e8169fd 394 Pfam PF13088 BNR repeat-like domain 34 369 2.1E-61 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS00940 46572034fdb105726bc2e30c6e8169fd 394 Gene3D G3DSA:2.120.10.10 309 388 3.9E-62 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS00940 46572034fdb105726bc2e30c6e8169fd 394 Gene3D G3DSA:2.120.10.10 19 265 3.9E-62 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS00940 46572034fdb105726bc2e30c6e8169fd 394 SUPERFAMILY SSF50939 308 387 7.57E-49 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS00940 46572034fdb105726bc2e30c6e8169fd 394 SUPERFAMILY SSF50939 19 266 7.57E-49 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS13545 a0e7a7c2a7894f6f238605d2b0823f7b 445 SMART SM00345 7 66 1.2E-9 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS13545 a0e7a7c2a7894f6f238605d2b0823f7b 445 Gene3D G3DSA:3.40.640.10 121 331 1.4E-46 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS13545 a0e7a7c2a7894f6f238605d2b0823f7b 445 SUPERFAMILY SSF53383 115 435 2.99E-63 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS13545 a0e7a7c2a7894f6f238605d2b0823f7b 445 Pfam PF00155 Aminotransferase class I and II 125 430 2.5E-16 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS13545 a0e7a7c2a7894f6f238605d2b0823f7b 445 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.6E-11 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS13545 a0e7a7c2a7894f6f238605d2b0823f7b 445 Gene3D G3DSA:1.10.10.10 4 67 4.4E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13545 a0e7a7c2a7894f6f238605d2b0823f7b 445 SUPERFAMILY SSF46785 4 82 6.53E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14615 a654aa06bc264acf82ba0a59b0f63375 227 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 10 185 1.5E-62 T 09-03-2017 IPR023932 Uncharacterised protein family, CE1759 UA74_RS14615 a654aa06bc264acf82ba0a59b0f63375 227 SUPERFAMILY SSF52218 9 167 2.19E-27 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS14615 a654aa06bc264acf82ba0a59b0f63375 227 Gene3D G3DSA:3.40.50.360 6 179 3.0E-31 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS14615 a654aa06bc264acf82ba0a59b0f63375 227 Pfam PF03358 NADPH-dependent FMN reductase 10 159 8.8E-30 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS25155 68df42cbb2e97a448b1cb2222e74fb3a 327 Gene3D G3DSA:3.20.20.100 1 314 6.3E-101 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS25155 68df42cbb2e97a448b1cb2222e74fb3a 327 Pfam PF00248 Aldo/keto reductase family 15 312 6.9E-76 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS25155 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 9.0E-6 T 09-03-2017 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_RS25155 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 256 268 9.0E-6 T 09-03-2017 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_RS25155 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 269 282 9.0E-6 T 09-03-2017 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_RS25155 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 203 209 9.0E-6 T 09-03-2017 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_RS25155 68df42cbb2e97a448b1cb2222e74fb3a 327 SUPERFAMILY SSF51430 1 313 4.19E-97 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS03365 4cd215e2bf322fa42c9ffeda0592d1ee 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.9E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS03365 4cd215e2bf322fa42c9ffeda0592d1ee 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.9E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS03365 4cd215e2bf322fa42c9ffeda0592d1ee 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.4E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS03365 4cd215e2bf322fa42c9ffeda0592d1ee 201 SUPERFAMILY SSF46689 8 76 1.2E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS03365 4cd215e2bf322fa42c9ffeda0592d1ee 201 Gene3D G3DSA:1.10.357.10 11 184 1.3E-20 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15015 ecad227bfb8e682b1b4903501ee3fe32 190 Pfam PF04434 SWIM zinc finger 125 144 2.2E-4 T 09-03-2017 IPR007527 Zinc finger, SWIM-type GO:0008270 UA74_RS27590 3922eb6e05049cd2317b4369098e7e15 297 Pfam PF00171 Aldehyde dehydrogenase family 33 264 7.0E-40 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS27590 3922eb6e05049cd2317b4369098e7e15 297 SUPERFAMILY SSF53720 15 263 1.44E-45 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS27590 3922eb6e05049cd2317b4369098e7e15 297 Gene3D G3DSA:3.40.605.10 15 264 2.0E-54 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS03165 49247f5b0dde0915d98e438eb5789368 416 SUPERFAMILY SSF55874 308 412 1.92E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03165 49247f5b0dde0915d98e438eb5789368 416 Pfam PF07730 Histidine kinase 225 292 2.3E-13 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS03165 49247f5b0dde0915d98e438eb5789368 416 Pfam PF13796 Putative sensor 30 196 1.9E-16 T 09-03-2017 IPR025828 Putative sensor domain UA74_RS01140 0da301d2706505874ba9eb4f5b0d64b4 320 SUPERFAMILY SSF56300 43 284 3.07E-25 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS01140 0da301d2706505874ba9eb4f5b0d64b4 320 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 48 232 9.1E-9 T 09-03-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 UA74_RS01140 0da301d2706505874ba9eb4f5b0d64b4 320 Gene3D G3DSA:3.60.21.10 46 247 4.4E-16 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS07800 de4d8edb0ef304f40021eb8e81593701 85 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 18 82 4.2E-11 T 09-03-2017 IPR008792 Coenzyme PQQ synthesis D UA74_RS27045 101d01b7f045f6d430e66307325adade 134 Gene3D G3DSA:3.30.1310.10 6 93 2.5E-5 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS27045 101d01b7f045f6d430e66307325adade 134 Pfam PF02575 YbaB/EbfC DNA-binding family 18 98 1.5E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS05305 ac1471723bee3f400c60ff788aa4b4c7 254 Pfam PF01061 ABC-2 type transporter 7 203 3.0E-23 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS05305 ac1471723bee3f400c60ff788aa4b4c7 254 PIRSF PIRSF006648 3 254 9.2E-15 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS11515 d6b8e7d655854f89fd06f04932a03c6e 415 SUPERFAMILY SSF55931 31 260 2.26E-30 T 09-03-2017 UA74_RS11515 d6b8e7d655854f89fd06f04932a03c6e 415 SUPERFAMILY SSF55931 296 365 2.26E-30 T 09-03-2017 UA74_RS11515 d6b8e7d655854f89fd06f04932a03c6e 415 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 15 415 30.121 T 09-03-2017 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_RS11515 d6b8e7d655854f89fd06f04932a03c6e 415 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 41 338 1.4E-44 T 09-03-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_RS11515 d6b8e7d655854f89fd06f04932a03c6e 415 PIRSF PIRSF017901 5 407 2.1E-82 T 09-03-2017 UA74_RS12820 6b8915dca36ba81141a42852fc99aa56 226 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 34 178 1.9E-21 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_RS12820 6b8915dca36ba81141a42852fc99aa56 226 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 34 214 5.3E-14 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_RS12820 6b8915dca36ba81141a42852fc99aa56 226 SUPERFAMILY SSF109854 28 181 5.49E-15 T 09-03-2017 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 Pfam PF00815 Histidinol dehydrogenase 22 435 9.4E-155 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 09-03-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 4.6E-83 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 Gene3D G3DSA:3.40.50.1980 29 247 2.1E-74 T 09-03-2017 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 SUPERFAMILY SSF53720 25 436 5.49E-69 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 3.4E-139 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 PIRSF PIRSF000099 1 439 7.0E-149 T 09-03-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS09970 44dc0c1f7a4f58f739ddde9e5629859f 440 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 436 38.312 T 09-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_RS23510 b2498f8bf21494d497dac5fea60d3a40 199 SUPERFAMILY SSF55729 7 193 8.86E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS23510 b2498f8bf21494d497dac5fea60d3a40 199 Gene3D G3DSA:3.40.630.30 6 198 6.1E-38 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS23510 b2498f8bf21494d497dac5fea60d3a40 199 Pfam PF00583 Acetyltransferase (GNAT) family 119 175 1.2E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 SUPERFAMILY SSF52440 9 125 6.76E-45 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 Pfam PF00289 Biotin carboxylase, N-terminal domain 15 122 1.7E-41 T 09-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 SMART SM00878 348 456 1.3E-58 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 Gene3D G3DSA:3.30.470.20 217 460 6.8E-94 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 SUPERFAMILY SSF51246 343 458 5.76E-38 T 09-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.3E-70 T 09-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 SUPERFAMILY SSF56059 96 362 4.42E-67 T 09-03-2017 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 Pfam PF02785 Biotin carboxylase C-terminal domain 348 457 1.1E-36 T 09-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 Gene3D G3DSA:3.40.50.20 15 142 6.2E-45 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS11125 59cad30e897425ba5cc1883e5c481d63 476 Gene3D G3DSA:3.30.1490.20 143 215 1.1E-23 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS20460 787f316dd82b4762398da463e7eeabab 220 Pfam PF01323 DSBA-like thioredoxin domain 12 212 3.3E-44 T 09-03-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 UA74_RS20460 787f316dd82b4762398da463e7eeabab 220 Gene3D G3DSA:3.40.30.10 9 213 2.2E-50 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS20460 787f316dd82b4762398da463e7eeabab 220 SUPERFAMILY SSF52833 10 218 2.86E-50 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS15160 0a0a209b140a83f4702fefd83b0b7242 276 SUPERFAMILY SSF141571 188 269 2.9E-19 T 09-03-2017 UA74_RS15160 0a0a209b140a83f4702fefd83b0b7242 276 SUPERFAMILY SSF141571 60 96 2.9E-19 T 09-03-2017 UA74_RS15160 0a0a209b140a83f4702fefd83b0b7242 276 Pfam PF00805 Pentapeptide repeats (8 copies) 192 225 2.4E-10 T 09-03-2017 IPR001646 Pentapeptide repeat UA74_RS19480 0bb91ca7a1ea559db3c636aad64537d7 346 Gene3D G3DSA:3.40.50.1980 56 175 3.5E-12 T 09-03-2017 UA74_RS19480 0bb91ca7a1ea559db3c636aad64537d7 346 SUPERFAMILY SSF53807 60 338 4.71E-36 T 09-03-2017 UA74_RS19480 0bb91ca7a1ea559db3c636aad64537d7 346 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 21 47 6.8E-4 T 09-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UA74_RS19480 0bb91ca7a1ea559db3c636aad64537d7 346 Gene3D G3DSA:3.40.50.1980 176 342 7.1E-23 T 09-03-2017 UA74_RS19480 0bb91ca7a1ea559db3c636aad64537d7 346 Pfam PF01497 Periplasmic binding protein 84 319 1.4E-15 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS23595 7614849bee53bbb4746d1f13233eed98 405 Pfam PF01594 Domain of unknown function DUF20 34 355 1.8E-59 T 09-03-2017 IPR002549 Transmembrane protein TqsA-like UA74_RS03210 0451ce426e83879ca3f9a813736f38b8 232 SMART SM00862 152 227 5.5E-26 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS03210 0451ce426e83879ca3f9a813736f38b8 232 Gene3D G3DSA:3.40.50.2300 1 121 1.5E-43 T 09-03-2017 UA74_RS03210 0451ce426e83879ca3f9a813736f38b8 232 SUPERFAMILY SSF52172 1 186 5.69E-44 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS03210 0451ce426e83879ca3f9a813736f38b8 232 SMART SM00448 1 112 2.4E-46 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS03210 0451ce426e83879ca3f9a813736f38b8 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 2.8E-25 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS03210 0451ce426e83879ca3f9a813736f38b8 232 Pfam PF00072 Response regulator receiver domain 3 112 3.7E-32 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS03210 0451ce426e83879ca3f9a813736f38b8 232 Gene3D G3DSA:1.10.10.10 132 229 7.2E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23725 81a9a4083d0575159bbc3c60b0f77501 356 SUPERFAMILY SSF52540 61 244 5.58E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23725 81a9a4083d0575159bbc3c60b0f77501 356 Gene3D G3DSA:3.40.50.300 16 203 7.5E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23725 81a9a4083d0575159bbc3c60b0f77501 356 Pfam PF03969 AFG1-like ATPase 235 336 3.3E-15 T 09-03-2017 IPR005654 ATPase, AFG1-like GO:0005524 UA74_RS23725 81a9a4083d0575159bbc3c60b0f77501 356 Pfam PF03969 AFG1-like ATPase 36 226 1.2E-39 T 09-03-2017 IPR005654 ATPase, AFG1-like GO:0005524 UA74_RS22080 221028ef198b4dfa87eea0c55a833a8a 163 Pfam PF00589 Phage integrase family 7 109 4.8E-7 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS22080 221028ef198b4dfa87eea0c55a833a8a 163 Gene3D G3DSA:1.10.443.10 10 116 3.2E-14 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS22080 221028ef198b4dfa87eea0c55a833a8a 163 SUPERFAMILY SSF56349 13 116 7.65E-15 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 Gene3D G3DSA:2.40.10.10 70 137 4.5E-14 T 09-03-2017 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 SUPERFAMILY SSF50494 55 265 1.41E-35 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 SMART SM00020 60 261 7.0E-13 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 95 100 - T 09-03-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 Gene3D G3DSA:2.40.10.10 138 264 4.2E-12 T 09-03-2017 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 Pfam PF00089 Trypsin 68 261 8.8E-22 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 131 145 1.1E-6 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 213 225 1.1E-6 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS05640 d528270ea555eece0dbef747507bc8cf 267 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 85 100 1.1E-6 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS12670 584fbe817e6ca45532e6ea388749946a 832 SUPERFAMILY SSF48208 305 771 5.83E-47 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS12670 584fbe817e6ca45532e6ea388749946a 832 Gene3D G3DSA:1.50.10.10 409 619 6.5E-11 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS12670 584fbe817e6ca45532e6ea388749946a 832 Gene3D G3DSA:2.70.98.50 22 408 2.6E-49 T 09-03-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 UA74_RS12670 584fbe817e6ca45532e6ea388749946a 832 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 22 280 7.5E-15 T 09-03-2017 IPR027414 Glycosyl hydrolase family, N-terminal domain KEGG: 00511+3.2.1.51 UA74_RS12410 111f53ae155800225cc4fb31ce3237dd 156 Pfam PF10756 Bacterial PH domain 76 146 2.9E-20 T 09-03-2017 IPR019692 Protein of unknown function DUF2581 UA74_RS00805 7b42e30726907dbe663fa99d5bee2f19 417 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 113 159 6.8E-13 T 09-03-2017 IPR023849 Uncharacterised domain CHP03934, TQXA UA74_RS00805 7b42e30726907dbe663fa99d5bee2f19 417 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 381 413 5.4E-4 T 09-03-2017 IPR019931 LPXTG cell wall anchor domain UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 Gene3D G3DSA:3.40.50.300 441 531 2.3E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 574 1.0E-171 T 09-03-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 Gene3D G3DSA:3.40.50.300 2 210 6.2E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 SUPERFAMILY SSF52540 5 50 3.68E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 SUPERFAMILY SSF52540 403 532 3.68E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 SUPERFAMILY SSF52540 2 221 2.94E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 PIRSF PIRSF003128 1 579 4.8E-151 T 09-03-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 UA74_RS21595 887258015e2bb7507d2799c90b2e1751 587 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 529 1.4E-13 T 09-03-2017 IPR003395 RecF/RecN/SMC, N-terminal UA74_RS27915 dc3ac1fea959b2a9b9000a6252ee2cc8 468 Pfam PF05977 Transmembrane secretion effector 10 412 1.3E-26 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS27915 dc3ac1fea959b2a9b9000a6252ee2cc8 468 SUPERFAMILY SSF103473 8 400 2.35E-47 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS27915 dc3ac1fea959b2a9b9000a6252ee2cc8 468 Gene3D G3DSA:1.20.1250.20 226 405 4.0E-19 T 09-03-2017 UA74_RS27915 dc3ac1fea959b2a9b9000a6252ee2cc8 468 Gene3D G3DSA:1.20.1250.20 8 196 4.3E-18 T 09-03-2017 UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 Gene3D G3DSA:2.60.40.420 219 347 3.6E-31 T 09-03-2017 IPR008972 Cupredoxin UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 SUPERFAMILY SSF49503 57 217 4.58E-26 T 09-03-2017 IPR008972 Cupredoxin UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 SUPERFAMILY SSF49503 414 524 5.94E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 Pfam PF07731 Multicopper oxidase 416 524 1.2E-22 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 SUPERFAMILY SSF49503 220 346 2.13E-23 T 09-03-2017 IPR008972 Cupredoxin UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 Pfam PF00394 Multicopper oxidase 254 347 4.0E-5 T 09-03-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 Gene3D G3DSA:2.60.40.420 69 218 1.9E-28 T 09-03-2017 IPR008972 Cupredoxin UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 Gene3D G3DSA:2.60.40.420 392 524 2.4E-31 T 09-03-2017 IPR008972 Cupredoxin UA74_RS22490 c13551c50e3e1ed9a564cd38597d7005 525 Pfam PF07732 Multicopper oxidase 90 216 1.2E-16 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS20340 ab4373f8025f72bd9d9aa1b81cd7f218 266 Gene3D G3DSA:3.40.50.1820 1 248 1.3E-20 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20340 ab4373f8025f72bd9d9aa1b81cd7f218 266 SUPERFAMILY SSF53474 1 249 1.53E-20 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Gene3D G3DSA:3.10.20.70 5 107 4.0E-36 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 SMART SM01230 104 383 6.9E-150 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 5.9E-25 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 09-03-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 390 402 - T 09-03-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 SUPERFAMILY SSF54368 5 103 1.83E-31 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 09-03-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 4.1E-134 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 SUPERFAMILY SSF55931 105 473 4.41E-137 T 09-03-2017 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 473 2.0E-202 T 09-03-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25255 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Gene3D G3DSA:3.30.590.10 108 454 9.8E-133 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 14 316 29.472 T 09-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 SUPERFAMILY SSF56042 155 305 9.63E-30 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 39 148 2.4E-20 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 15 318 4.0E-82 T 09-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 PIRSF PIRSF005303 9 319 1.8E-87 T 09-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 Gene3D G3DSA:3.30.1330.10 10 150 1.1E-43 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 SUPERFAMILY SSF55326 12 148 8.52E-34 T 09-03-2017 UA74_RS25935 abc499c2337cb036c565a77b6025f9ff 322 Gene3D G3DSA:3.90.650.10 157 318 2.0E-47 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS01960 61ed8a5fdde7bd034231b5988b9c4c0b 313 Gene3D G3DSA:1.10.3720.10 15 298 6.6E-50 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01960 61ed8a5fdde7bd034231b5988b9c4c0b 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 301 4.7E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01960 61ed8a5fdde7bd034231b5988b9c4c0b 313 SUPERFAMILY SSF161098 69 297 1.44E-52 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21690 e4cde5dc29966d24d42d2c2e324f75fe 392 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 8 391 1.9E-114 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_RS21690 e4cde5dc29966d24d42d2c2e324f75fe 392 Pfam PF01960 ArgJ family 17 392 9.7E-133 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_RS21690 e4cde5dc29966d24d42d2c2e324f75fe 392 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 392 135.401 T 09-03-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_RS21690 e4cde5dc29966d24d42d2c2e324f75fe 392 Gene3D G3DSA:3.60.70.12 8 268 4.6E-92 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_RS21690 e4cde5dc29966d24d42d2c2e324f75fe 392 SUPERFAMILY SSF56266 13 388 1.31E-125 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_RS21690 e4cde5dc29966d24d42d2c2e324f75fe 392 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 37 390 8.0E-103 T 09-03-2017 UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 Gene3D G3DSA:2.40.50.100 374 388 6.5E-9 T 09-03-2017 UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 Gene3D G3DSA:2.40.50.100 240 284 6.5E-9 T 09-03-2017 UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 Pfam PF00005 ABC transporter 21 162 6.4E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 Gene3D G3DSA:3.40.50.300 4 235 2.9E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 Gene3D G3DSA:2.40.50.140 285 372 8.1E-10 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 SUPERFAMILY SSF52540 4 242 1.5E-83 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 SMART SM00382 29 212 1.8E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04675 bd2d3bf188b2a3d20534890febdfb541 392 SUPERFAMILY SSF50331 237 388 2.75E-20 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS11980 dbfd22e8a35c44e92410230711d939bd 357 SUPERFAMILY SSF56112 5 322 2.62E-28 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS11980 dbfd22e8a35c44e92410230711d939bd 357 Pfam PF01636 Phosphotransferase enzyme family 31 298 2.0E-22 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS11980 dbfd22e8a35c44e92410230711d939bd 357 Gene3D G3DSA:3.90.1200.10 112 298 5.3E-15 T 09-03-2017 UA74_RS03025 e8e8b41f9c6cb6b03b6274329e2ddb13 147 Gene3D G3DSA:3.100.10.10 33 146 4.2E-31 T 09-03-2017 UA74_RS03025 e8e8b41f9c6cb6b03b6274329e2ddb13 147 SUPERFAMILY SSF52080 8 146 5.49E-39 T 09-03-2017 IPR021131 Ribosomal protein L18e/L15P UA74_RS03025 e8e8b41f9c6cb6b03b6274329e2ddb13 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 147 19.069 T 09-03-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 UA74_RS03025 e8e8b41f9c6cb6b03b6274329e2ddb13 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 141 - T 09-03-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS03025 e8e8b41f9c6cb6b03b6274329e2ddb13 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 144 7.3E-43 T 09-03-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03025 e8e8b41f9c6cb6b03b6274329e2ddb13 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 145 2.2E-30 T 09-03-2017 IPR021131 Ribosomal protein L18e/L15P UA74_RS14610 32b664dee68b7fdf35c83b3b7daccb34 395 Pfam PF00296 Luciferase-like monooxygenase 1 264 6.2E-51 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS14610 32b664dee68b7fdf35c83b3b7daccb34 395 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 353 2.5E-185 T 09-03-2017 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative UA74_RS14610 32b664dee68b7fdf35c83b3b7daccb34 395 SUPERFAMILY SSF51679 1 332 1.13E-63 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS14610 32b664dee68b7fdf35c83b3b7daccb34 395 Gene3D G3DSA:3.20.20.30 1 338 1.1E-69 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 SUPERFAMILY SSF53850 95 284 4.98E-37 T 09-03-2017 UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.0E-19 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.3E-6 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.3E-6 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.3E-6 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 Gene3D G3DSA:3.40.190.10 183 267 7.9E-20 T 09-03-2017 UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 SUPERFAMILY SSF46785 6 114 4.96E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 Pfam PF03466 LysR substrate binding domain 92 284 9.8E-43 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 Gene3D G3DSA:1.10.10.10 6 89 2.7E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13320 a7fd01047e41184a62ea0199daed4368 299 Gene3D G3DSA:3.40.190.10 93 182 3.2E-15 T 09-03-2017 UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 Gene3D G3DSA:3.40.50.2300 185 331 1.2E-42 T 09-03-2017 UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 SUPERFAMILY SSF53822 77 355 3.14E-54 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 Gene3D G3DSA:1.10.260.40 17 68 1.2E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 SUPERFAMILY SSF47413 16 74 4.64E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 SMART SM00354 16 86 1.2E-20 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 63 1.2E-13 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 Pfam PF13377 Periplasmic binding protein-like domain 182 349 5.2E-32 T 09-03-2017 UA74_RS18130 8e74c5aff00604c482c19b17d8b32c34 357 Gene3D G3DSA:3.40.50.2300 69 184 2.0E-29 T 09-03-2017 UA74_RS21995 ef5c511dde760893d00eca64819e8cc6 488 SUPERFAMILY SSF51445 36 396 8.44E-22 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS21995 ef5c511dde760893d00eca64819e8cc6 488 Gene3D G3DSA:3.20.20.80 45 323 1.0E-22 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS13655 83bf086d6c30426df90de991bfd18250 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 348 406 5.5E-18 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain UA74_RS13920 dd70143e566e36a8b3faa0b429db603c 630 Gene3D G3DSA:2.130.10.10 5 262 6.4E-24 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS13920 dd70143e566e36a8b3faa0b429db603c 630 SUPERFAMILY SSF82171 21 250 1.7E-22 T 09-03-2017 UA74_RS13920 dd70143e566e36a8b3faa0b429db603c 630 SUPERFAMILY SSF82171 305 353 1.7E-22 T 09-03-2017 UA74_RS13920 dd70143e566e36a8b3faa0b429db603c 630 Gene3D G3DSA:3.40.50.1820 300 623 2.3E-73 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS13920 dd70143e566e36a8b3faa0b429db603c 630 Pfam PF00326 Prolyl oligopeptidase family 414 624 1.4E-31 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS13920 dd70143e566e36a8b3faa0b429db603c 630 SUPERFAMILY SSF53474 293 627 1.68E-54 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17165 ea0ef8db1ca81d6171cb325385dbf917 266 Pfam PF00975 Thioesterase domain 18 123 1.9E-29 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS17165 ea0ef8db1ca81d6171cb325385dbf917 266 SUPERFAMILY SSF53474 4 264 9.89E-54 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17165 ea0ef8db1ca81d6171cb325385dbf917 266 SMART SM00824 Thioesterase 20 184 1.6E-5 T 09-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_RS17165 ea0ef8db1ca81d6171cb325385dbf917 266 Gene3D G3DSA:3.40.50.1820 202 264 8.3E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17165 ea0ef8db1ca81d6171cb325385dbf917 266 Gene3D G3DSA:3.40.50.1820 5 121 8.3E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 5.8E-14 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 4.7E-9 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SUPERFAMILY SSF81923 7 157 6.97E-32 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:1.10.8.60 346 429 4.7E-36 T 09-03-2017 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:3.40.50.300 555 776 4.6E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:1.10.8.60 777 856 3.5E-29 T 09-03-2017 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 09-03-2017 IPR028299 ClpA/B, conserved site 2 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 759 3.8E-52 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SUPERFAMILY SSF52540 159 547 1.07E-94 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SUPERFAMILY SSF52540 548 848 6.81E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:1.10.1780.10 2 148 1.1E-37 T 09-03-2017 IPR004176 Clp, N-terminal GO:0019538 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SMART SM00382 199 345 1.2E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SMART SM00382 599 746 1.3E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 7.5E-26 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 851 0.0 T 09-03-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 3.2E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 3.2E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 3.2E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 3.2E-41 T 09-03-2017 IPR001270 ClpA/B family GO:0005524 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 318 1.2E-11 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:3.40.50.300 160 343 2.3E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SMART SM01086 766 857 5.6E-33 T 09-03-2017 IPR019489 Clp ATPase, C-terminal UA74_RS29780 0fcc9f90c3cf4315d44e9f517d49c7bd 865 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 09-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 UA74_RS15530 e60a624e64bfdf7fef3743034faca2bb 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 6.8E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15530 e60a624e64bfdf7fef3743034faca2bb 205 Gene3D G3DSA:1.10.357.10 3 189 1.6E-21 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15530 e60a624e64bfdf7fef3743034faca2bb 205 SUPERFAMILY SSF46689 3 74 7.18E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07380 fda68c14be5dba5fbb98007ec3472a03 209 Gene3D G3DSA:3.40.50.720 1 195 3.0E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07380 fda68c14be5dba5fbb98007ec3472a03 209 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 97 1.0E-12 T 09-03-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_RS07380 fda68c14be5dba5fbb98007ec3472a03 209 SUPERFAMILY SSF51735 1 202 1.62E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 SMART SM00422 118 187 1.4E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 SMART SM00422 1 69 0.011 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 SUPERFAMILY SSF46955 5 107 3.48E-13 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 Gene3D G3DSA:1.10.1660.10 5 107 3.7E-15 T 09-03-2017 UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 Gene3D G3DSA:1.10.1660.10 118 235 3.4E-21 T 09-03-2017 UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 Pfam PF13411 MerR HTH family regulatory protein 119 186 3.6E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 Pfam PF00376 MerR family regulatory protein 5 39 1.1E-9 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 SUPERFAMILY SSF46955 118 230 2.01E-18 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS19805 ec4b514a312a0a21a8bd75f34800e1ff 245 ProSitePatterns PS00552 MerR-type HTH domain signature. 121 143 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS11175 a15b583026fe84c274eb9db693a0c80b 270 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 128 143 1.4E-5 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS11175 a15b583026fe84c274eb9db693a0c80b 270 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 197 212 1.4E-5 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS11175 a15b583026fe84c274eb9db693a0c80b 270 Gene3D G3DSA:2.40.100.10 111 268 1.6E-38 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS11175 a15b583026fe84c274eb9db693a0c80b 270 SUPERFAMILY SSF50891 115 269 1.61E-36 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS11175 a15b583026fe84c274eb9db693a0c80b 270 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 116 267 6.6E-26 T 09-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 UA74_RS14585 6e20d92473e56b2e6cf067c2d3a6d205 193 Gene3D G3DSA:1.10.357.10 5 189 3.1E-29 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS14585 6e20d92473e56b2e6cf067c2d3a6d205 193 SUPERFAMILY SSF48498 100 186 1.05E-8 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS14585 6e20d92473e56b2e6cf067c2d3a6d205 193 SUPERFAMILY SSF46689 8 77 2.84E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14585 6e20d92473e56b2e6cf067c2d3a6d205 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 2.7E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 Pfam PF08281 Sigma-70, region 4 102 155 1.5E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 SUPERFAMILY SSF88946 4 89 1.41E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 Pfam PF04542 Sigma-70 region 2 22 79 1.2E-9 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 Gene3D G3DSA:1.10.1740.10 5 79 1.7E-13 T 09-03-2017 UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 Gene3D G3DSA:1.10.10.10 99 160 5.1E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 SUPERFAMILY SSF88659 100 159 2.43E-13 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 6 160 1.4E-44 T 09-03-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_RS00395 3489b1da902e483cd527cc8c17b1aeb2 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 158 1.5E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS10060 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 SUPERFAMILY SSF141734 8 114 1.05E-45 T 09-03-2017 UA74_RS10060 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 59 108 3.0E-20 T 09-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UA74_RS10060 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 10 113 31.564 T 09-03-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UA74_RS10060 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 36 108 1.4E-33 T 09-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UA74_RS00115 fa47cacf0a841f5a6834e77670b6a832 134 Gene3D G3DSA:3.10.450.50 5 124 1.7E-22 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS00115 fa47cacf0a841f5a6834e77670b6a832 134 Pfam PF12680 SnoaL-like domain 14 113 9.1E-11 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS00115 fa47cacf0a841f5a6834e77670b6a832 134 SUPERFAMILY SSF54427 6 123 2.73E-20 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Gene3D G3DSA:3.90.960.10 254 393 2.5E-6 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 581 36.398 T 09-03-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 SUPERFAMILY SSF55826 255 385 1.06E-9 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Pfam PF03129 Anticodon binding domain 493 578 4.4E-18 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Gene3D G3DSA:3.30.930.10 12 236 1.4E-91 T 09-03-2017 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Gene3D G3DSA:3.30.930.10 402 482 1.4E-91 T 09-03-2017 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 SUPERFAMILY SSF52954 477 581 6.34E-28 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 SUPERFAMILY SSF55681 12 239 7.65E-87 T 09-03-2017 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 SUPERFAMILY SSF55681 420 490 7.65E-87 T 09-03-2017 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 576 3.2E-165 T 09-03-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.6E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.6E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 1.6E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.6E-15 T 09-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Gene3D G3DSA:3.40.50.800 483 580 3.4E-25 T 09-03-2017 IPR004154 Anticodon-binding UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 471 4.7E-37 T 09-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS09280 26e15011ffef84277ded12f1c12aba90 582 Pfam PF04073 Aminoacyl-tRNA editing domain 259 387 1.3E-20 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS28535 85b4ef7cf41052050822ff41e46806e1 288 SUPERFAMILY SSF46689 32 91 3.54E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS28535 85b4ef7cf41052050822ff41e46806e1 288 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 80 3.3E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS28535 85b4ef7cf41052050822ff41e46806e1 288 Gene3D G3DSA:1.10.10.60 29 84 2.2E-22 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS28535 85b4ef7cf41052050822ff41e46806e1 288 SUPERFAMILY SSF48498 98 241 7.56E-24 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS28535 85b4ef7cf41052050822ff41e46806e1 288 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 95 235 4.7E-19 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS28535 85b4ef7cf41052050822ff41e46806e1 288 Gene3D G3DSA:1.10.357.10 85 239 2.0E-34 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS27270 e1868b7f7fc3e23da31481e202a8c48e 290 Pfam PF01040 UbiA prenyltransferase family 30 174 5.0E-15 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 UA74_RS27680 baa5d294e91f33be24ca426826776f28 145 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 23 126 1.3E-22 T 09-03-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27680 baa5d294e91f33be24ca426826776f28 145 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 24 127 4.3E-27 T 09-03-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27680 baa5d294e91f33be24ca426826776f28 145 SUPERFAMILY SSF81343 23 132 1.96E-26 T 09-03-2017 UA74_RS27680 baa5d294e91f33be24ca426826776f28 145 Gene3D G3DSA:1.20.1300.10 23 129 2.2E-29 T 09-03-2017 UA74_RS22200 609836439343de19a582c80a16ab0dd0 405 Gene3D G3DSA:1.20.1250.20 8 191 4.8E-18 T 09-03-2017 UA74_RS22200 609836439343de19a582c80a16ab0dd0 405 Gene3D G3DSA:1.20.1250.20 217 397 1.7E-19 T 09-03-2017 UA74_RS22200 609836439343de19a582c80a16ab0dd0 405 SUPERFAMILY SSF103473 7 397 1.7E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22200 609836439343de19a582c80a16ab0dd0 405 Pfam PF07690 Major Facilitator Superfamily 19 329 1.1E-21 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 SUPERFAMILY SSF48452 339 473 4.81E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 Pfam PF00069 Protein kinase domain 4 280 7.1E-40 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 5 28 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 SMART SM00220 1 287 2.1E-44 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 Gene3D G3DSA:1.25.40.10 338 473 2.3E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 Gene3D G3DSA:1.10.510.10 139 283 1.0E-40 T 09-03-2017 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 Gene3D G3DSA:3.30.200.20 4 138 1.2E-17 T 09-03-2017 UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 SUPERFAMILY SSF56112 3 288 1.86E-60 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS10325 de72dddd618c92e4f9f38a9dc286677a 519 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 144 156 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS28160 165155f37992dcc557ad80420667feac 401 Gene3D G3DSA:2.40.37.10 232 381 8.8E-57 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_RS28160 165155f37992dcc557ad80420667feac 401 Hamap MF_01201 Alanine racemase. 9 379 30.891 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 SUPERFAMILY SSF50621 246 378 1.19E-46 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_RS28160 165155f37992dcc557ad80420667feac 401 Pfam PF01168 Alanine racemase, N-terminal domain 16 239 2.6E-60 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 Gene3D G3DSA:3.20.20.10 19 231 1.3E-66 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS28160 165155f37992dcc557ad80420667feac 401 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 41 51 - T 09-03-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 Pfam PF00842 Alanine racemase, C-terminal domain 251 371 1.8E-38 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 TIGRFAM TIGR00492 alr: alanine racemase 13 371 6.1E-84 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 SUPERFAMILY SSF51419 16 252 2.62E-56 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS28160 165155f37992dcc557ad80420667feac 401 SMART SM01005 251 379 4.2E-59 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 267 282 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 36 52 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 284 299 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 72 90 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 170 181 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 212 239 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 305 322 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 133 145 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS28160 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 360 373 2.2E-59 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 Pfam PF00583 Acetyltransferase (GNAT) family 70 156 2.4E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 Pfam PF00583 Acetyltransferase (GNAT) family 239 320 6.2E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 SUPERFAMILY SSF55729 49 167 1.95E-15 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 SUPERFAMILY SSF55729 134 322 1.51E-33 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 Gene3D G3DSA:3.40.630.30 48 164 3.5E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 4 327 5.2E-86 T 09-03-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 Gene3D G3DSA:3.40.630.30 185 321 1.4E-28 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 PIRSF PIRSF021524 1 330 7.9E-105 T 09-03-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 UA74_RS29285 9f1a869261584e76573469a0fd787e22 330 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 2 330 33.58 T 09-03-2017 IPR017813 Mycothiol acetyltransferase GO:0016747 UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 379 494 3.4E-13 T 09-03-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 251 9.6E-93 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 Gene3D G3DSA:3.40.47.10 264 429 2.7E-63 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 Gene3D G3DSA:3.40.47.10 3 263 2.0E-93 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 SMART SM00825 Beta-ketoacyl synthase 3 429 4.7E-222 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 164 180 - T 09-03-2017 IPR018201 Beta-ketoacyl synthase, active site UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 376 1.6E-42 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS16520 4e1cccb696cf6a5d87c5cc53c08bbd29 502 SUPERFAMILY SSF53901 1 366 9.16E-104 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18820 97351d96a67157e6a3f7242d26c2baaa 413 Pfam PF13416 Bacterial extracellular solute-binding protein 57 351 9.1E-31 T 09-03-2017 UA74_RS18820 97351d96a67157e6a3f7242d26c2baaa 413 Gene3D G3DSA:3.40.190.10 46 167 1.2E-14 T 09-03-2017 UA74_RS18820 97351d96a67157e6a3f7242d26c2baaa 413 SUPERFAMILY SSF53850 21 410 4.3E-65 T 09-03-2017 UA74_RS18820 97351d96a67157e6a3f7242d26c2baaa 413 Gene3D G3DSA:3.40.190.10 168 347 2.0E-34 T 09-03-2017 UA74_RS22190 838cc41261905cfda713d7890598b792 447 Gene3D G3DSA:1.20.1250.20 47 221 2.3E-9 T 09-03-2017 UA74_RS22190 838cc41261905cfda713d7890598b792 447 Pfam PF07690 Major Facilitator Superfamily 53 382 1.0E-20 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS22190 838cc41261905cfda713d7890598b792 447 SUPERFAMILY SSF103473 34 427 2.35E-43 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22190 838cc41261905cfda713d7890598b792 447 Gene3D G3DSA:1.20.1250.20 249 439 5.4E-19 T 09-03-2017 UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 Pfam PF12833 Helix-turn-helix domain 239 317 2.0E-19 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 SUPERFAMILY SSF46689 269 320 1.34E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 Gene3D G3DSA:1.10.10.60 223 269 8.2E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 SUPERFAMILY SSF52317 5 198 4.58E-49 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 SUPERFAMILY SSF46689 218 267 4.93E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 SMART SM00342 233 316 2.3E-24 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 Gene3D G3DSA:1.10.10.60 270 320 6.3E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 Gene3D G3DSA:3.40.50.880 7 222 5.0E-54 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS18355 8e591cccd644241e5cac89d6004f0719 330 Pfam PF01965 DJ-1/PfpI family 6 177 5.2E-25 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 SUPERFAMILY SSF55729 123 279 2.3E-29 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 26 41 1.6E-5 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.6E-5 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 Pfam PF12840 Helix-turn-helix domain 24 83 1.0E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 Gene3D G3DSA:1.10.10.10 11 94 1.0E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 Pfam PF00583 Acetyltransferase (GNAT) family 174 254 6.5E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 SMART SM00418 24 110 5.4E-13 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 Gene3D G3DSA:3.40.630.30 122 279 2.4E-35 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS19570 e610898d13acf5364c0f624215afbb60 301 SUPERFAMILY SSF46785 20 93 3.09E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28135 4f805937f29e8d6c4b9c7dac97b54df7 534 PIRSF PIRSF001363 1 534 2.0E-230 T 09-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS28135 4f805937f29e8d6c4b9c7dac97b54df7 534 Gene3D G3DSA:3.20.20.360 71 414 2.0E-117 T 09-03-2017 UA74_RS28135 4f805937f29e8d6c4b9c7dac97b54df7 534 SUPERFAMILY SSF51645 7 532 4.84E-180 T 09-03-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS28135 4f805937f29e8d6c4b9c7dac97b54df7 534 Pfam PF01274 Malate synthase 13 531 3.8E-185 T 09-03-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS28135 4f805937f29e8d6c4b9c7dac97b54df7 534 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 09-03-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS28135 4f805937f29e8d6c4b9c7dac97b54df7 534 Gene3D G3DSA:1.20.1220.12 416 527 3.0E-27 T 09-03-2017 UA74_RS28135 4f805937f29e8d6c4b9c7dac97b54df7 534 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 22 533 4.3E-228 T 09-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS03775 21d75f7b15ed55d92f2f4ddf3c172e3d 250 Gene3D G3DSA:3.40.470.10 17 244 4.6E-50 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS03775 21d75f7b15ed55d92f2f4ddf3c172e3d 250 SUPERFAMILY SSF52141 26 239 3.6E-40 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS03775 21d75f7b15ed55d92f2f4ddf3c172e3d 250 SMART SM00987 58 236 8.1E-30 T 09-03-2017 UA74_RS03775 21d75f7b15ed55d92f2f4ddf3c172e3d 250 Pfam PF03167 Uracil DNA glycosylase superfamily 58 236 8.0E-26 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS03775 21d75f7b15ed55d92f2f4ddf3c172e3d 250 SMART SM00986 58 236 8.1E-30 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 PIRSF PIRSF000535 1 301 1.5E-68 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 Gene3D G3DSA:3.40.1190.20 35 294 4.8E-71 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 295 3.7E-92 T 09-03-2017 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 295 1.0E-94 T 09-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 Pfam PF00294 pfkB family carbohydrate kinase 15 291 8.0E-42 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 Gene3D G3DSA:2.20.150.10 9 34 2.3E-8 T 09-03-2017 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 UA74_RS16715 9ee62ef8e39ad48d7f98e9b5c7164721 314 SUPERFAMILY SSF53613 2 291 3.74E-60 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS29625 fc97060073ba04189255de1abf054db2 353 Pfam PF13515 Fusaric acid resistance protein-like 21 143 4.1E-14 T 09-03-2017 UA74_RS17310 84589695e567034695ecfa633fdad210 256 SUPERFAMILY SSF53335 29 235 5.85E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17310 84589695e567034695ecfa633fdad210 256 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 55 214 8.6E-36 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS17310 84589695e567034695ecfa633fdad210 256 Gene3D G3DSA:3.40.50.150 42 200 9.0E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17310 84589695e567034695ecfa633fdad210 256 Pfam PF05050 Methyltransferase FkbM domain 57 233 1.0E-21 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS20615 0991a662b4f27eb2c58ad8432c24a5fc 697 Pfam PF13361 UvrD-like helicase C-terminal domain 615 686 2.3E-12 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS20615 0991a662b4f27eb2c58ad8432c24a5fc 697 Gene3D G3DSA:3.40.50.300 502 696 6.0E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20615 0991a662b4f27eb2c58ad8432c24a5fc 697 SUPERFAMILY SSF52540 238 693 9.56E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20615 0991a662b4f27eb2c58ad8432c24a5fc 697 Pfam PF00580 UvrD/REP helicase N-terminal domain 433 485 6.1E-11 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS20615 0991a662b4f27eb2c58ad8432c24a5fc 697 Pfam PF13245 Part of AAA domain 259 324 2.7E-10 T 09-03-2017 UA74_RS20615 0991a662b4f27eb2c58ad8432c24a5fc 697 Gene3D G3DSA:3.40.50.300 388 485 1.8E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20615 0991a662b4f27eb2c58ad8432c24a5fc 697 Gene3D G3DSA:3.40.50.300 241 356 1.8E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01165 85f2cb7551cb622ef1a7bc7ed2bdddd8 389 SUPERFAMILY SSF52540 24 197 1.08E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01165 85f2cb7551cb622ef1a7bc7ed2bdddd8 389 SUPERFAMILY SSF52540 239 326 1.08E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01165 85f2cb7551cb622ef1a7bc7ed2bdddd8 389 Gene3D G3DSA:3.40.50.300 19 186 9.5E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01165 85f2cb7551cb622ef1a7bc7ed2bdddd8 389 Gene3D G3DSA:3.40.50.300 241 301 9.5E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01165 85f2cb7551cb622ef1a7bc7ed2bdddd8 389 Pfam PF02374 Anion-transporting ATPase 28 299 2.5E-23 T 09-03-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_RS00785 732a4f7f6ad3c9c3a8f9a8ed51a0d436 235 SUPERFAMILY SSF53474 4 234 1.29E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS00785 732a4f7f6ad3c9c3a8f9a8ed51a0d436 235 Gene3D G3DSA:3.40.50.1820 8 235 1.3E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS00785 732a4f7f6ad3c9c3a8f9a8ed51a0d436 235 Pfam PF01738 Dienelactone hydrolase family 18 233 2.6E-24 T 09-03-2017 IPR002925 Dienelactone hydrolase GO:0016787 UA74_RS14230 37f93e3b5bf97c058ad72d31eee6c75e 301 PIRSF PIRSF028754 4 296 2.1E-104 T 09-03-2017 IPR008492 Protein of unknown function DUF774 UA74_RS14230 37f93e3b5bf97c058ad72d31eee6c75e 301 Pfam PF09754 PAC2 family 27 245 7.7E-48 T 09-03-2017 IPR019151 Proteasome assembly chaperone 2 UA74_RS14230 37f93e3b5bf97c058ad72d31eee6c75e 301 SUPERFAMILY SSF159659 14 267 2.35E-86 T 09-03-2017 UA74_RS17095 75633be907b65cf055bc459cca968f56 628 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 18 531 4.9E-126 T 09-03-2017 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 UA74_RS17095 75633be907b65cf055bc459cca968f56 628 SUPERFAMILY SSF48208 126 347 2.61E-24 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS17095 75633be907b65cf055bc459cca968f56 628 Gene3D G3DSA:1.50.10.10 110 279 5.1E-11 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS17085 65a640b3c7d6888a3ee7280b3e053821 303 Gene3D G3DSA:1.10.3720.10 92 299 1.8E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS17085 65a640b3c7d6888a3ee7280b3e053821 303 SUPERFAMILY SSF161098 94 285 3.92E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS17085 65a640b3c7d6888a3ee7280b3e053821 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 301 1.8E-30 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04595 1f94cabb9482305621ef24f56aa30be8 296 SUPERFAMILY SSF46785 15 120 1.36E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04595 1f94cabb9482305621ef24f56aa30be8 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 72 1.9E-14 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS04595 1f94cabb9482305621ef24f56aa30be8 296 SUPERFAMILY SSF53850 98 295 2.79E-41 T 09-03-2017 UA74_RS04595 1f94cabb9482305621ef24f56aa30be8 296 Gene3D G3DSA:1.10.10.10 15 87 7.7E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04595 1f94cabb9482305621ef24f56aa30be8 296 Pfam PF03466 LysR substrate binding domain 97 295 3.9E-48 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS04595 1f94cabb9482305621ef24f56aa30be8 296 Gene3D G3DSA:3.40.190.10 99 185 3.3E-21 T 09-03-2017 UA74_RS04595 1f94cabb9482305621ef24f56aa30be8 296 Gene3D G3DSA:3.40.190.10 186 269 3.6E-28 T 09-03-2017 UA74_RS18875 473bdd877b07c2a932d63ecfe5aa327a 292 SUPERFAMILY SSF161098 23 292 5.63E-64 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18875 473bdd877b07c2a932d63ecfe5aa327a 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 285 7.3E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18875 473bdd877b07c2a932d63ecfe5aa327a 292 Gene3D G3DSA:1.10.3720.10 21 279 9.0E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07225 17055a571ab993abfbbb050a55797a40 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 215 1.9E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07225 17055a571ab993abfbbb050a55797a40 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 5.8E-28 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 UA74_RS07225 17055a571ab993abfbbb050a55797a40 221 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 4 215 2.8E-85 T 09-03-2017 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD UA74_RS07225 17055a571ab993abfbbb050a55797a40 221 Gene3D G3DSA:1.10.3720.10 11 215 1.5E-41 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07225 17055a571ab993abfbbb050a55797a40 221 SUPERFAMILY SSF161098 15 201 1.7E-37 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08455 7685727213e6282a3dc77be6bb96eae8 108 Pfam PF11298 Protein of unknown function (DUF3099) 14 82 4.3E-28 T 09-03-2017 IPR021449 Protein of unknown function DUF3099 UA74_RS18075 42ea03f44eab6c7fff3bde301e715d2d 180 SUPERFAMILY SSF109854 9 168 4.88E-31 T 09-03-2017 UA74_RS18075 42ea03f44eab6c7fff3bde301e715d2d 180 Pfam PF04978 Protein of unknown function (DUF664) 10 169 2.1E-19 T 09-03-2017 IPR007061 Protein of unknown function DUF664 UA74_RS18075 42ea03f44eab6c7fff3bde301e715d2d 180 Gene3D G3DSA:1.20.120.450 5 171 1.8E-65 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS03680 fc5b518a97d84009dac2ba362cf0c0fd 316 Pfam PF07885 Ion channel 123 199 1.7E-14 T 09-03-2017 IPR013099 Potassium channel domain UA74_RS03680 fc5b518a97d84009dac2ba362cf0c0fd 316 SUPERFAMILY SSF81324 17 198 5.42E-34 T 09-03-2017 UA74_RS03680 fc5b518a97d84009dac2ba362cf0c0fd 316 PRINTS PR01333 Two pore domain K+ channel signature 288 297 2.1E-6 T 09-03-2017 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 UA74_RS03680 fc5b518a97d84009dac2ba362cf0c0fd 316 PRINTS PR01333 Two pore domain K+ channel signature 155 183 2.1E-6 T 09-03-2017 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 UA74_RS03680 fc5b518a97d84009dac2ba362cf0c0fd 316 Gene3D G3DSA:1.10.287.70 16 198 6.3E-31 T 09-03-2017 UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 PIRSF PIRSF000728 22 300 4.9E-99 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 TIGRFAM TIGR00761 argB: acetylglutamate kinase 38 276 2.3E-76 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 Hamap MF_00082_B Acetylglutamate kinase [argB]. 35 301 33.868 T 09-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 PRINTS PR00474 Glutamate 5-kinase family signature 68 82 1.1E-8 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 PRINTS PR00474 Glutamate 5-kinase family signature 200 227 1.1E-8 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 PRINTS PR00474 Glutamate 5-kinase family signature 251 271 1.1E-8 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 Gene3D G3DSA:3.40.1160.10 36 300 2.6E-99 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 Pfam PF00696 Amino acid kinase family 38 278 1.3E-44 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS21685 049d1b8abb7e931f02ab608fdf2ba10d 306 SUPERFAMILY SSF53633 19 302 6.55E-86 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS28050 5811480981590ed91c29bb9e636ad062 195 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 134 189 7.3E-11 T 09-03-2017 UA74_RS08985 9391e5efa06dcb3a332c0c842923a180 357 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 326 1.8E-21 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS08985 9391e5efa06dcb3a332c0c842923a180 357 SUPERFAMILY SSF52540 9 260 8.11E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08985 9391e5efa06dcb3a332c0c842923a180 357 Gene3D G3DSA:3.40.50.300 8 263 3.0E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08985 9391e5efa06dcb3a332c0c842923a180 357 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS08985 9391e5efa06dcb3a332c0c842923a180 357 SMART SM00382 37 239 1.9E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08985 9391e5efa06dcb3a332c0c842923a180 357 Pfam PF00005 ABC transporter 29 189 1.9E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS08985 9391e5efa06dcb3a332c0c842923a180 357 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 1.1E-17 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF47644 636 719 7.45E-23 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF51717 340 611 1.83E-74 T 09-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 PIRSF PIRSF000381 3 1187 0.0 T 09-03-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.20.20.20 348 610 8.4E-84 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 TIGRFAM TIGR02082 metH: methionine synthase 14 1186 0.0 T 09-03-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 971 1186 1.1E-31 T 09-03-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.40.50.280 723 866 3.6E-47 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02607 B12 binding domain 642 713 3.8E-23 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SMART SM01018 638 720 5.0E-39 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF00809 Pterin binding enzyme 344 579 7.5E-45 T 09-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF52242 720 856 1.37E-38 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF82282 7 382 4.32E-105 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.10.196.10 957 1186 9.8E-63 T 09-03-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02574 Homocysteine S-methyltransferase 18 308 2.7E-67 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:1.10.1240.10 632 717 1.1E-29 T 09-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF56507 900 1187 1.83E-84 T 09-03-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02310 B12 binding domain 726 844 2.5E-19 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS14235 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.20.20.330 5 347 2.4E-106 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS15935 ef0e67b0126185b3b61c379d69dc263a 326 Pfam PF01867 CRISPR associated protein Cas1 10 278 1.3E-67 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS15935 ef0e67b0126185b3b61c379d69dc263a 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 6 326 9.1E-97 T 09-03-2017 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 UA74_RS15935 ef0e67b0126185b3b61c379d69dc263a 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 10 320 1.4E-72 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS15935 ef0e67b0126185b3b61c379d69dc263a 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 5 311 22.167 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 Gene3D G3DSA:3.20.20.80 168 601 1.2E-110 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 Gene3D G3DSA:2.60.40.10 14 167 2.1E-45 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 14 724 7.3E-255 T 09-03-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 SUPERFAMILY SSF81296 14 138 2.38E-36 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 SMART SM00642 170 593 2.4E-7 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 18 108 2.2E-16 T 09-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 SUPERFAMILY SSF51445 508 600 1.21E-126 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 SUPERFAMILY SSF51445 155 479 1.21E-126 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 Pfam PF00128 Alpha amylase, catalytic domain 200 283 4.8E-6 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 SUPERFAMILY SSF51011 613 725 5.9E-16 T 09-03-2017 UA74_RS06420 a44a45ed86f0c431d6774d7c31b3206d 732 Gene3D G3DSA:2.60.40.1180 613 725 1.0E-19 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 SUPERFAMILY SSF116734 449 596 4.41E-8 T 09-03-2017 UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 Pfam PF02384 N-6 DNA Methylase 133 329 8.0E-25 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 SUPERFAMILY SSF53335 131 343 3.93E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 243 249 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 274 298 6.5E-10 T 09-03-2017 UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 240 252 6.5E-10 T 09-03-2017 UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 176 190 6.5E-10 T 09-03-2017 UA74_RS02700 caf3717f77eed2fef0238e0907a8989b 610 Gene3D G3DSA:3.40.50.150 159 328 2.9E-24 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06675 d7f3e2708fd83d71fa65bb79a16672b6 105 Gene3D G3DSA:2.102.10.10 2 99 1.1E-30 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS06675 d7f3e2708fd83d71fa65bb79a16672b6 105 Pfam PF00355 Rieske [2Fe-2S] domain 2 86 9.4E-18 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS06675 d7f3e2708fd83d71fa65bb79a16672b6 105 SUPERFAMILY SSF50022 2 98 1.44E-30 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS28365 9dabb1a18e93f9d645ff46c2389d0500 335 SMART SM00829 19 333 2.7E-8 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS28365 9dabb1a18e93f9d645ff46c2389d0500 335 Pfam PF00107 Zinc-binding dehydrogenase 159 286 1.1E-24 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS28365 9dabb1a18e93f9d645ff46c2389d0500 335 Pfam PF16884 N-terminal domain of oxidoreductase 7 113 1.4E-37 T 09-03-2017 UA74_RS28365 9dabb1a18e93f9d645ff46c2389d0500 335 Gene3D G3DSA:3.90.180.10 2 141 5.5E-50 T 09-03-2017 IPR011032 GroES-like UA74_RS28365 9dabb1a18e93f9d645ff46c2389d0500 335 SUPERFAMILY SSF50129 6 144 1.4E-39 T 09-03-2017 IPR011032 GroES-like UA74_RS28365 9dabb1a18e93f9d645ff46c2389d0500 335 SUPERFAMILY SSF51735 123 300 8.68E-50 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28365 9dabb1a18e93f9d645ff46c2389d0500 335 Gene3D G3DSA:3.40.50.720 142 302 7.2E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 Gene3D G3DSA:3.40.50.1820 262 367 2.8E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 Gene3D G3DSA:3.40.50.1820 43 192 2.8E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 Pfam PF00005 ABC transporter 656 796 2.3E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 56 319 5.3E-17 T 09-03-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 SUPERFAMILY SSF52540 632 859 9.87E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 SMART SM00382 664 852 4.0E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 451 575 4.2E-9 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 Gene3D G3DSA:3.40.50.300 635 859 3.7E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 SMART SM00939 360 587 2.3E-7 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 SUPERFAMILY SSF53474 12 188 1.06E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 SUPERFAMILY SSF53474 289 368 1.06E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 ProSitePatterns PS00211 ABC transporters family signature. 768 782 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 Gene3D G3DSA:2.60.120.260 455 564 1.2E-14 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS10780 338fe5ebcaac43238da62d046df06ace 937 SUPERFAMILY SSF49785 419 589 1.25E-13 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS09615 25866d15525585f35e1956fe5b0c7850 144 SMART SM00530 12 67 1.2E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS09615 25866d15525585f35e1956fe5b0c7850 144 Pfam PF13560 Helix-turn-helix domain 8 65 1.5E-9 T 09-03-2017 UA74_RS09615 25866d15525585f35e1956fe5b0c7850 144 SUPERFAMILY SSF47413 4 71 5.91E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09615 25866d15525585f35e1956fe5b0c7850 144 Gene3D G3DSA:1.10.260.40 9 75 8.8E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13510 d0a4249152a069c300b35eb694236ceb 296 Pfam PF13560 Helix-turn-helix domain 17 82 1.8E-11 T 09-03-2017 UA74_RS13510 d0a4249152a069c300b35eb694236ceb 296 SUPERFAMILY SSF47413 12 78 5.2E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13510 d0a4249152a069c300b35eb694236ceb 296 SMART SM00530 20 80 1.4E-4 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS13510 d0a4249152a069c300b35eb694236ceb 296 Gene3D G3DSA:1.10.260.40 13 80 2.3E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16755 8022861f66d697f0472cd8ceb3a7f7b6 298 Pfam PF00376 MerR family regulatory protein 12 44 1.4E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS16755 8022861f66d697f0472cd8ceb3a7f7b6 298 Gene3D G3DSA:1.10.1660.10 14 63 1.4E-13 T 09-03-2017 UA74_RS16755 8022861f66d697f0472cd8ceb3a7f7b6 298 SUPERFAMILY SSF46955 13 64 1.24E-12 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS16755 8022861f66d697f0472cd8ceb3a7f7b6 298 SMART SM00422 12 66 8.1E-4 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS21655 1e3c3b5ac52bd58b5b3fa3946cd3ea5e 224 Gene3D G3DSA:3.10.300.10 14 215 1.2E-61 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_RS21655 1e3c3b5ac52bd58b5b3fa3946cd3ea5e 224 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 21 203 5.6E-59 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_RS21655 1e3c3b5ac52bd58b5b3fa3946cd3ea5e 224 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 15 207 7.2E-55 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_RS21655 1e3c3b5ac52bd58b5b3fa3946cd3ea5e 224 SUPERFAMILY SSF50486 14 213 2.75E-58 T 09-03-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 UA74_RS21655 1e3c3b5ac52bd58b5b3fa3946cd3ea5e 224 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 10 207 30.747 T 09-03-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_RS26530 bb6697f2c61233b934ad91fef72c028e 264 Pfam PF01614 Bacterial transcriptional regulator 127 252 1.5E-16 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS26530 bb6697f2c61233b934ad91fef72c028e 264 Gene3D G3DSA:1.10.10.10 6 79 5.6E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26530 bb6697f2c61233b934ad91fef72c028e 264 SUPERFAMILY SSF55781 72 258 1.05E-41 T 09-03-2017 IPR029016 GAF domain-like UA74_RS26530 bb6697f2c61233b934ad91fef72c028e 264 SMART SM00346 7 97 3.1E-19 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS26530 bb6697f2c61233b934ad91fef72c028e 264 SUPERFAMILY SSF46785 7 80 3.29E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26530 bb6697f2c61233b934ad91fef72c028e 264 Gene3D G3DSA:3.30.450.40 80 260 8.1E-48 T 09-03-2017 IPR029016 GAF domain-like UA74_RS26530 bb6697f2c61233b934ad91fef72c028e 264 Pfam PF09339 IclR helix-turn-helix domain 9 57 5.7E-12 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS11325 77c0988f57434538cfacbc638e12947d 397 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 205 225 - T 09-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UA74_RS11325 77c0988f57434538cfacbc638e12947d 397 Gene3D G3DSA:3.40.640.10 42 272 2.9E-59 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS11325 77c0988f57434538cfacbc638e12947d 397 Pfam PF00266 Aminotransferase class-V 21 384 6.6E-60 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS11325 77c0988f57434538cfacbc638e12947d 397 SUPERFAMILY SSF53383 6 390 6.95E-80 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS11325 77c0988f57434538cfacbc638e12947d 397 Gene3D G3DSA:3.90.1150.10 273 389 2.4E-30 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 156 171 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 326 341 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 89 100 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 281 292 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 139 155 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 199 221 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 298 325 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 347 356 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 356 367 1.1E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 Pfam PF00067 Cytochrome P450 82 379 1.5E-18 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 SUPERFAMILY SSF48264 13 402 4.98E-85 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 Gene3D G3DSA:1.10.630.10 9 402 1.4E-113 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS00435 75c4102239c8717e92c4a8ac92c79266 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS22395 4c01fa0bf844b5be331e2a811424e559 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 4.0E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22395 4c01fa0bf844b5be331e2a811424e559 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 4.0E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22395 4c01fa0bf844b5be331e2a811424e559 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 4.0E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22395 4c01fa0bf844b5be331e2a811424e559 275 SUPERFAMILY SSF53474 6 259 1.46E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22395 4c01fa0bf844b5be331e2a811424e559 275 Pfam PF12697 Alpha/beta hydrolase family 21 255 1.4E-17 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22395 4c01fa0bf844b5be331e2a811424e559 275 Gene3D G3DSA:3.40.50.1820 5 259 4.8E-43 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 SUPERFAMILY SSF46955 3 117 1.28E-29 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 SMART SM00422 3 72 2.6E-21 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 Gene3D G3DSA:1.10.1660.10 3 121 1.4E-31 T 09-03-2017 UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 3.9E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 3.9E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 3.9E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS27435 c85b1f64bd7d2b02b24d28fe96931e42 132 Pfam PF13411 MerR HTH family regulatory protein 3 68 6.6E-15 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS00240 b89a92c2eed4608f777f2afff42edc10 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 205 8.5E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00240 b89a92c2eed4608f777f2afff42edc10 215 Gene3D G3DSA:1.10.3720.10 7 197 2.5E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00240 b89a92c2eed4608f777f2afff42edc10 215 SUPERFAMILY SSF161098 14 199 6.15E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03200 b8cf1e7247749b3dc6e4b26e964b948a 110 Pfam PF07110 EthD domain 16 82 3.4E-8 T 09-03-2017 IPR009799 EthD domain UA74_RS03200 b8cf1e7247749b3dc6e4b26e964b948a 110 Gene3D G3DSA:3.30.70.900 1 102 3.0E-20 T 09-03-2017 UA74_RS03200 b8cf1e7247749b3dc6e4b26e964b948a 110 SUPERFAMILY SSF54909 1 101 4.45E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS03200 b8cf1e7247749b3dc6e4b26e964b948a 110 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 100 2.7E-14 T 09-03-2017 IPR009799 EthD domain UA74_RS14855 2eb661aac7595ebcfddf92dcd6371306 449 SUPERFAMILY SSF56219 79 349 5.76E-14 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS14855 2eb661aac7595ebcfddf92dcd6371306 449 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 16 31 - T 09-03-2017 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 UA74_RS14855 2eb661aac7595ebcfddf92dcd6371306 449 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 84 345 1.1E-8 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS14910 e4281f089ae68b0f6037ce83e806a952 414 Pfam PF07690 Major Facilitator Superfamily 22 249 2.8E-11 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS14910 e4281f089ae68b0f6037ce83e806a952 414 Pfam PF07690 Major Facilitator Superfamily 261 395 3.8E-9 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS14910 e4281f089ae68b0f6037ce83e806a952 414 SUPERFAMILY SSF103473 18 399 1.18E-36 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14910 e4281f089ae68b0f6037ce83e806a952 414 Gene3D G3DSA:1.20.1250.20 220 399 1.4E-15 T 09-03-2017 UA74_RS14910 e4281f089ae68b0f6037ce83e806a952 414 Gene3D G3DSA:1.20.1250.20 17 195 5.0E-14 T 09-03-2017 UA74_RS03205 2b4f3629059e79f60cd2d365074efbc1 202 Pfam PF03458 UPF0126 domain 90 159 9.8E-17 T 09-03-2017 IPR005115 Uncharacterised domain UPF0126 UA74_RS03205 2b4f3629059e79f60cd2d365074efbc1 202 Pfam PF03458 UPF0126 domain 4 78 3.0E-22 T 09-03-2017 IPR005115 Uncharacterised domain UPF0126 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 Pfam PF00288 GHMP kinases N terminal domain 81 140 1.7E-12 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 Gene3D G3DSA:3.30.70.890 161 262 4.1E-27 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 PIRSF PIRSF000676 1 276 6.1E-71 T 09-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 87 98 - T 09-03-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 TIGRFAM TIGR00191 thrB: homoserine kinase 4 263 2.4E-59 T 09-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 SUPERFAMILY SSF54211 4 149 5.31E-30 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 245 260 4.0E-30 T 09-03-2017 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 11 26 4.0E-30 T 09-03-2017 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 168 185 4.0E-30 T 09-03-2017 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 94 109 4.0E-30 T 09-03-2017 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 127 140 4.0E-30 T 09-03-2017 UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 SUPERFAMILY SSF55060 165 267 2.09E-20 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 Gene3D G3DSA:3.30.230.10 3 149 4.5E-50 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS07085 00de285d6bd8cb73f3e843d5d5a4328c 292 Hamap MF_00384 Homoserine kinase [thrB]. 4 289 27.203 T 09-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 Gene3D G3DSA:3.50.50.60 4 134 6.8E-38 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 5.5E-70 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 SUPERFAMILY SSF55424 333 457 2.06E-29 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 447 9.7E-25 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 457 1.4E-137 T 09-03-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 2.0E-73 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 Gene3D G3DSA:3.50.50.60 135 326 7.8E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 Gene3D G3DSA:3.30.390.30 337 458 8.0E-31 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PIRSF PIRSF000350 2 449 4.1E-74 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 3.6E-38 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 3.6E-38 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 3.6E-38 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.6E-38 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 3.6E-38 T 09-03-2017 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 SUPERFAMILY SSF51905 3 326 9.67E-61 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25210 44288104e7212a478c6fe35ff1baf56f 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 09-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UA74_RS24315 37b365e2da702ffb5096c24189f235cc 443 Pfam PF13416 Bacterial extracellular solute-binding protein 64 364 4.6E-31 T 09-03-2017 UA74_RS24315 37b365e2da702ffb5096c24189f235cc 443 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 154 171 - T 09-03-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 UA74_RS24315 37b365e2da702ffb5096c24189f235cc 443 Gene3D G3DSA:3.40.190.10 175 361 1.0E-39 T 09-03-2017 UA74_RS24315 37b365e2da702ffb5096c24189f235cc 443 Gene3D G3DSA:3.40.190.10 49 174 3.0E-21 T 09-03-2017 UA74_RS24315 37b365e2da702ffb5096c24189f235cc 443 SUPERFAMILY SSF53850 51 429 1.71E-67 T 09-03-2017 UA74_RS23005 46e56cf8d99dcbdad75db6b6dc549ac6 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 301 3.5E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23005 46e56cf8d99dcbdad75db6b6dc549ac6 314 SUPERFAMILY SSF161098 74 298 8.5E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23005 46e56cf8d99dcbdad75db6b6dc549ac6 314 Gene3D G3DSA:1.10.3720.10 23 301 1.2E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01220 9e86ec99f8711264160efe5cb9eddc69 439 Gene3D G3DSA:1.20.1250.20 36 197 2.9E-7 T 09-03-2017 UA74_RS01220 9e86ec99f8711264160efe5cb9eddc69 439 PRINTS PR01035 Tetracycline resistance protein signature 258 277 1.0E-4 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS01220 9e86ec99f8711264160efe5cb9eddc69 439 PRINTS PR01035 Tetracycline resistance protein signature 347 369 1.0E-4 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS01220 9e86ec99f8711264160efe5cb9eddc69 439 PRINTS PR01035 Tetracycline resistance protein signature 229 245 1.0E-4 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS01220 9e86ec99f8711264160efe5cb9eddc69 439 SUPERFAMILY SSF103473 24 404 1.96E-26 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS01220 9e86ec99f8711264160efe5cb9eddc69 439 Pfam PF07690 Major Facilitator Superfamily 27 337 4.4E-11 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS01220 9e86ec99f8711264160efe5cb9eddc69 439 Gene3D G3DSA:1.20.1250.20 222 404 1.8E-7 T 09-03-2017 UA74_RS14390 3704b5a1c53a9c004d7ed3c4d56d4152 321 Gene3D G3DSA:3.90.180.10 1 148 1.8E-27 T 09-03-2017 IPR011032 GroES-like UA74_RS14390 3704b5a1c53a9c004d7ed3c4d56d4152 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 09-03-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_RS14390 3704b5a1c53a9c004d7ed3c4d56d4152 321 SMART SM00829 10 317 3.4E-10 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS14390 3704b5a1c53a9c004d7ed3c4d56d4152 321 Gene3D G3DSA:3.40.50.720 149 286 3.3E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14390 3704b5a1c53a9c004d7ed3c4d56d4152 321 SUPERFAMILY SSF50129 1 152 3.62E-25 T 09-03-2017 IPR011032 GroES-like UA74_RS14390 3704b5a1c53a9c004d7ed3c4d56d4152 321 Pfam PF13602 Zinc-binding dehydrogenase 186 316 8.0E-21 T 09-03-2017 UA74_RS14390 3704b5a1c53a9c004d7ed3c4d56d4152 321 SUPERFAMILY SSF51735 119 260 3.7E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26815 bd39f617ebc32d55bcf62d76699c0dbd 333 Pfam PF01933 Uncharacterised protein family UPF0052 3 295 5.0E-63 T 09-03-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 UA74_RS26815 bd39f617ebc32d55bcf62d76699c0dbd 333 SUPERFAMILY SSF142338 3 329 8.24E-79 T 09-03-2017 UA74_RS26815 bd39f617ebc32d55bcf62d76699c0dbd 333 Gene3D G3DSA:3.40.50.10680 98 330 6.7E-78 T 09-03-2017 UA74_RS26815 bd39f617ebc32d55bcf62d76699c0dbd 333 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 333 130.936 T 09-03-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 UA74_RS26815 bd39f617ebc32d55bcf62d76699c0dbd 333 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 326 5.5E-117 T 09-03-2017 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 UA74_RS10645 db9235e29ca378997ab8e601a1f48fe1 323 Gene3D G3DSA:3.40.50.1980 158 321 1.2E-36 T 09-03-2017 UA74_RS10645 db9235e29ca378997ab8e601a1f48fe1 323 SUPERFAMILY SSF53807 39 315 5.49E-43 T 09-03-2017 UA74_RS10645 db9235e29ca378997ab8e601a1f48fe1 323 Pfam PF01497 Periplasmic binding protein 58 299 1.1E-16 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS10645 db9235e29ca378997ab8e601a1f48fe1 323 Gene3D G3DSA:3.40.50.1980 37 157 2.3E-22 T 09-03-2017 UA74_RS12640 8cda922e8c36104b087a3eaad50c9bee 136 SUPERFAMILY SSF117916 33 130 5.23E-27 T 09-03-2017 UA74_RS12640 8cda922e8c36104b087a3eaad50c9bee 136 Pfam PF01883 Domain of unknown function DUF59 34 99 7.2E-20 T 09-03-2017 IPR002744 Domain of unknown function DUF59 UA74_RS01930 59c0484659de385b5105ba5bdf89a15e 228 SUPERFAMILY SSF50494 95 219 2.02E-10 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS01930 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 147 164 1.8E-20 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01930 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 191 205 1.8E-20 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01930 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 126 146 1.8E-20 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01930 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 166 189 1.8E-20 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01930 59c0484659de385b5105ba5bdf89a15e 228 Gene3D G3DSA:2.40.10.10 123 222 7.6E-16 T 09-03-2017 UA74_RS25030 8b7a2bb3c5d9aac7dd3518cbdf255d25 95 SUPERFAMILY SSF54909 2 77 2.95E-16 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS25030 8b7a2bb3c5d9aac7dd3518cbdf255d25 95 Gene3D G3DSA:3.30.70.920 3 78 3.9E-22 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS25030 8b7a2bb3c5d9aac7dd3518cbdf255d25 95 Pfam PF01037 Lrp/AsnC ligand binding domain 13 76 1.1E-13 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 Gene3D G3DSA:1.20.1250.20 3 195 3.6E-12 T 09-03-2017 UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 Hamap MF_00165 Thymidylate kinase [tmk]. 471 662 15.546 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 Pfam PF02223 Thymidylate kinase 485 649 1.2E-10 T 09-03-2017 UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 Pfam PF05977 Transmembrane secretion effector 241 407 2.3E-6 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 Pfam PF05977 Transmembrane secretion effector 3 166 1.3E-7 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 SUPERFAMILY SSF52540 470 657 1.11E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 SUPERFAMILY SSF103473 230 442 3.53E-30 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 SUPERFAMILY SSF103473 2 201 3.53E-30 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 Gene3D G3DSA:1.20.1250.20 255 450 2.0E-12 T 09-03-2017 UA74_RS01420 d73f4bcd43461e995fa0c50d0c98544c 693 Gene3D G3DSA:3.40.50.300 470 663 6.0E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05705 4c3b5e25d374671a033493d24563989f 268 Gene3D G3DSA:1.10.10.10 6 76 5.4E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05705 4c3b5e25d374671a033493d24563989f 268 Pfam PF09339 IclR helix-turn-helix domain 18 66 5.9E-13 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS05705 4c3b5e25d374671a033493d24563989f 268 Pfam PF01614 Bacterial transcriptional regulator 134 260 3.5E-8 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS05705 4c3b5e25d374671a033493d24563989f 268 SMART SM00346 16 105 1.5E-15 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS05705 4c3b5e25d374671a033493d24563989f 268 Gene3D G3DSA:3.30.450.40 86 260 4.1E-31 T 09-03-2017 IPR029016 GAF domain-like UA74_RS05705 4c3b5e25d374671a033493d24563989f 268 SUPERFAMILY SSF46785 16 85 2.59E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05705 4c3b5e25d374671a033493d24563989f 268 SUPERFAMILY SSF55781 93 260 1.83E-27 T 09-03-2017 IPR029016 GAF domain-like UA74_RS11840 451e6e7b92f27521a98140d88d29127f 239 PIRSF PIRSF008292 1 235 8.2E-90 T 09-03-2017 IPR016538 Uncharacterised conserved protein UCP008292 UA74_RS11840 451e6e7b92f27521a98140d88d29127f 239 Pfam PF00149 Calcineurin-like phosphoesterase 2 204 1.2E-11 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS11840 451e6e7b92f27521a98140d88d29127f 239 SUPERFAMILY SSF56300 2 224 9.77E-31 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS11840 451e6e7b92f27521a98140d88d29127f 239 Gene3D G3DSA:3.60.21.10 2 238 5.7E-26 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS04760 fa5e7edc389ac976fc0199c4fdbb7ac0 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.6E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04760 fa5e7edc389ac976fc0199c4fdbb7ac0 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.6E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04760 fa5e7edc389ac976fc0199c4fdbb7ac0 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.7E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04760 fa5e7edc389ac976fc0199c4fdbb7ac0 210 SUPERFAMILY SSF48498 92 204 4.6E-24 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS04760 fa5e7edc389ac976fc0199c4fdbb7ac0 210 Gene3D G3DSA:1.10.357.10 16 203 4.4E-40 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS04760 fa5e7edc389ac976fc0199c4fdbb7ac0 210 SUPERFAMILY SSF46689 13 92 3.94E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS26035 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 SUPERFAMILY SSF52016 1 187 5.69E-53 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS26035 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.5E-54 T 09-03-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 UA74_RS26035 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 38.32 T 09-03-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 UA74_RS26035 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 Pfam PF00694 Aconitase C-terminal domain 1 115 4.4E-23 T 09-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 UA74_RS26035 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 Gene3D G3DSA:3.20.19.10 1 186 2.4E-39 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS16475 578f318c49d90fa57ec4dfaefdd29541 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 127 180 3.1E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16475 578f318c49d90fa57ec4dfaefdd29541 202 Pfam PF08448 PAS fold 7 114 2.0E-6 T 09-03-2017 IPR013656 PAS fold-4 UA74_RS16475 578f318c49d90fa57ec4dfaefdd29541 202 Gene3D G3DSA:1.10.10.10 126 186 7.1E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16475 578f318c49d90fa57ec4dfaefdd29541 202 SUPERFAMILY SSF46894 122 187 1.63E-11 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS16475 578f318c49d90fa57ec4dfaefdd29541 202 Gene3D G3DSA:3.30.450.20 2 106 5.8E-8 T 09-03-2017 UA74_RS16475 578f318c49d90fa57ec4dfaefdd29541 202 SMART SM00421 124 181 1.6E-4 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16475 578f318c49d90fa57ec4dfaefdd29541 202 SUPERFAMILY SSF55785 2 105 4.33E-8 T 09-03-2017 IPR000014 PAS domain UA74_RS02550 466528da198da2715aed4569e7eade5a 232 SUPERFAMILY SSF143243 76 228 8.89E-50 T 09-03-2017 UA74_RS02550 466528da198da2715aed4569e7eade5a 232 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 140 201 5.0E-21 T 09-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02550 466528da198da2715aed4569e7eade5a 232 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 91 212 8.3E-45 T 09-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02550 466528da198da2715aed4569e7eade5a 232 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 60 220 29.709 T 09-03-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02550 466528da198da2715aed4569e7eade5a 232 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 90 211 1.7E-44 T 09-03-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 Pfam PF00326 Prolyl oligopeptidase family 373 578 8.5E-34 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 Gene3D G3DSA:2.120.10.30 146 296 4.5E-16 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 SUPERFAMILY SSF82171 24 307 2.22E-23 T 09-03-2017 UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 378 402 3.8E-6 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 438 458 3.8E-6 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 352 370 3.8E-6 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 512 534 3.8E-6 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 Gene3D G3DSA:3.40.50.1820 337 578 7.1E-52 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 Gene3D G3DSA:2.120.10.30 22 145 2.5E-5 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS17720 947c5bc941c4aa910379af7639a192b7 589 SUPERFAMILY SSF53474 278 582 1.17E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20070 ec1dfc60529e7b47c8df921439df982c 457 Gene3D G3DSA:1.20.1250.20 21 220 3.0E-41 T 09-03-2017 UA74_RS20070 ec1dfc60529e7b47c8df921439df982c 457 Pfam PF07690 Major Facilitator Superfamily 27 399 2.8E-44 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS20070 ec1dfc60529e7b47c8df921439df982c 457 Gene3D G3DSA:1.20.1250.20 242 437 2.3E-13 T 09-03-2017 UA74_RS20070 ec1dfc60529e7b47c8df921439df982c 457 SUPERFAMILY SSF103473 12 436 4.84E-77 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS00100 32c35479536205d48a9ba6fd1d134c0d 262 SUPERFAMILY SSF63817 26 244 6.04E-28 T 09-03-2017 IPR023365 Sortase domain UA74_RS00100 32c35479536205d48a9ba6fd1d134c0d 262 Gene3D G3DSA:2.40.260.10 62 165 1.5E-19 T 09-03-2017 IPR023365 Sortase domain UA74_RS00100 32c35479536205d48a9ba6fd1d134c0d 262 Gene3D G3DSA:2.40.260.10 214 247 1.5E-19 T 09-03-2017 IPR023365 Sortase domain UA74_RS00100 32c35479536205d48a9ba6fd1d134c0d 262 Pfam PF04203 Sortase family 71 243 7.6E-27 T 09-03-2017 IPR005754 Sortase family UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 SUPERFAMILY SSF56112 15 280 3.33E-73 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 SMART SM00740 594 662 8.1E-10 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 SMART SM00740 665 722 0.79 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 SMART SM00740 458 524 0.006 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 SMART SM00740 529 593 0.0038 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 Gene3D G3DSA:1.10.510.10 103 275 1.1E-47 T 09-03-2017 UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 140 152 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 Gene3D G3DSA:3.30.200.20 8 100 1.4E-22 T 09-03-2017 UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 Pfam PF03793 PASTA domain 667 721 9.1E-6 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 Pfam PF03793 PASTA domain 464 524 7.0E-8 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 Pfam PF03793 PASTA domain 534 593 7.7E-10 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 Pfam PF03793 PASTA domain 598 661 3.5E-10 T 09-03-2017 IPR005543 PASTA domain UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 Pfam PF00069 Protein kinase domain 19 234 3.0E-45 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS24815 d1362c2e01e5944041f71a3c1b5c9e53 723 SMART SM00220 17 278 3.3E-59 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS13645 7408e84c67fd0d34c039cb77f1e3566c 329 SUPERFAMILY SSF50129 2 142 2.28E-33 T 09-03-2017 IPR011032 GroES-like UA74_RS13645 7408e84c67fd0d34c039cb77f1e3566c 329 Gene3D G3DSA:3.40.50.720 149 264 7.4E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13645 7408e84c67fd0d34c039cb77f1e3566c 329 Pfam PF00107 Zinc-binding dehydrogenase 154 269 1.4E-28 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS13645 7408e84c67fd0d34c039cb77f1e3566c 329 SMART SM00829 13 325 7.3E-43 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS13645 7408e84c67fd0d34c039cb77f1e3566c 329 Gene3D G3DSA:3.90.180.10 2 148 5.5E-43 T 09-03-2017 IPR011032 GroES-like UA74_RS13645 7408e84c67fd0d34c039cb77f1e3566c 329 SUPERFAMILY SSF51735 115 270 3.82E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13645 7408e84c67fd0d34c039cb77f1e3566c 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 2.0E-9 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS03375 dd0eed328bd3547d2526f2dc96f970f1 338 SUPERFAMILY SSF51735 1 140 1.14E-12 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03375 dd0eed328bd3547d2526f2dc96f970f1 338 Gene3D G3DSA:3.40.50.720 1 158 5.2E-17 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03375 dd0eed328bd3547d2526f2dc96f970f1 338 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 123 5.3E-6 T 09-03-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 UA74_RS03765 c4ef28508004325fbd75ea5ab0cf36c5 492 Pfam PF00450 Serine carboxypeptidase 82 214 3.6E-9 T 09-03-2017 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 UA74_RS03765 c4ef28508004325fbd75ea5ab0cf36c5 492 Gene3D G3DSA:3.40.50.1820 24 481 1.1E-53 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS03765 c4ef28508004325fbd75ea5ab0cf36c5 492 SUPERFAMILY SSF53474 34 480 1.64E-71 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06720 7b9bb3bc01294740f98137215b065593 138 Gene3D G3DSA:3.10.180.10 7 126 1.8E-6 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS06720 7b9bb3bc01294740f98137215b065593 138 SUPERFAMILY SSF54593 3 129 7.66E-11 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS28615 70d67e8efbe5a4af9a5691a9dfb8d201 763 Pfam PF13625 Helicase conserved C-terminal domain 468 590 1.3E-39 T 09-03-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 UA74_RS17695 b27802ca66cd497363c6dda668eb7001 363 Gene3D G3DSA:3.40.718.10 4 334 3.4E-30 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS17695 b27802ca66cd497363c6dda668eb7001 363 SUPERFAMILY SSF53659 4 344 2.69E-28 T 09-03-2017 UA74_RS17695 b27802ca66cd497363c6dda668eb7001 363 SMART SM01329 4 340 3.0E-7 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS17695 b27802ca66cd497363c6dda668eb7001 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 107 339 3.0E-13 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 151 7.4E-36 T 09-03-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 PIRSF PIRSF000102 1 318 9.6E-92 T 09-03-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 149 167 2.1E-24 T 09-03-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 179 192 2.1E-24 T 09-03-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 6 30 2.1E-24 T 09-03-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 31 55 2.1E-24 T 09-03-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 125 145 2.1E-24 T 09-03-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 Gene3D G3DSA:3.90.110.10 153 316 4.6E-50 T 09-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 SUPERFAMILY SSF51735 6 151 9.88E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 SUPERFAMILY SSF56327 153 311 1.27E-45 T 09-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 Gene3D G3DSA:3.40.50.720 5 151 2.9E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27770 be0db59e4bcc19fe1d024a50c74064d7 318 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 312 4.1E-18 T 09-03-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 UA74_RS02670 2cf44624443f1c35137a4744add96f31 232 Pfam PF00005 ABC transporter 22 170 3.7E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS02670 2cf44624443f1c35137a4744add96f31 232 SUPERFAMILY SSF52540 4 223 2.13E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02670 2cf44624443f1c35137a4744add96f31 232 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS02670 2cf44624443f1c35137a4744add96f31 232 SMART SM00382 31 218 2.6E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS02670 2cf44624443f1c35137a4744add96f31 232 Gene3D G3DSA:3.40.50.300 3 222 1.5E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07645 5aa92eda2cf405fb2c9abb194fd28476 161 SUPERFAMILY SSF54427 49 155 5.42E-13 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS07645 5aa92eda2cf405fb2c9abb194fd28476 161 Gene3D G3DSA:3.10.450.50 53 156 6.4E-10 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS07645 5aa92eda2cf405fb2c9abb194fd28476 161 Pfam PF12680 SnoaL-like domain 61 154 3.2E-8 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 Pfam PF08281 Sigma-70, region 4 153 204 6.1E-17 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 Gene3D G3DSA:1.10.1740.10 41 114 1.3E-26 T 09-03-2017 UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 Gene3D G3DSA:1.10.10.10 149 210 5.8E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 67 98 - T 09-03-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 207 1.5E-27 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 36 220 9.0E-107 T 09-03-2017 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 SUPERFAMILY SSF88659 151 209 2.24E-17 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 SUPERFAMILY SSF88946 42 125 4.97E-23 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS26640 fb9b06fc91efcf22c6c3d82c05d28209 228 Pfam PF04542 Sigma-70 region 2 49 112 1.5E-18 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS20835 7ce9b9b797ee3770a0980d548c809802 243 Gene3D G3DSA:3.10.350.10 181 229 9.4E-4 T 09-03-2017 IPR018392 LysM domain UA74_RS06555 bd0b0e77a9db224262c499c4a0342d22 458 Gene3D G3DSA:3.30.300.30 360 444 4.0E-16 T 09-03-2017 UA74_RS06555 bd0b0e77a9db224262c499c4a0342d22 458 Pfam PF13193 AMP-binding enzyme C-terminal domain 374 441 2.4E-10 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS06555 bd0b0e77a9db224262c499c4a0342d22 458 SUPERFAMILY SSF56801 11 444 7.72E-74 T 09-03-2017 UA74_RS06555 bd0b0e77a9db224262c499c4a0342d22 458 Pfam PF00501 AMP-binding enzyme 14 309 1.1E-29 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS06555 bd0b0e77a9db224262c499c4a0342d22 458 Gene3D G3DSA:3.40.50.980 6 145 7.2E-12 T 09-03-2017 UA74_RS06555 bd0b0e77a9db224262c499c4a0342d22 458 Gene3D G3DSA:3.40.50.980 146 287 6.0E-23 T 09-03-2017 UA74_RS00190 43d767878c61d7eeae549fc0fc44e311 342 SUPERFAMILY SSF53335 148 333 1.35E-18 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00190 43d767878c61d7eeae549fc0fc44e311 342 Gene3D G3DSA:3.40.50.150 144 330 9.8E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00190 43d767878c61d7eeae549fc0fc44e311 342 Pfam PF13649 Methyltransferase domain 209 277 1.6E-6 T 09-03-2017 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 Gene3D G3DSA:3.90.380.10 164 421 1.8E-55 T 09-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 201 420 3.1E-19 T 09-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 Pfam PF00355 Rieske [2Fe-2S] domain 54 136 1.1E-17 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 SUPERFAMILY SSF55961 175 421 1.96E-43 T 09-03-2017 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 158 184 2.2E-28 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 89 109 2.2E-28 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 68 83 2.2E-28 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 110 130 2.2E-28 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 197 219 2.2E-28 T 09-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 SUPERFAMILY SSF50022 20 172 2.62E-46 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 96 119 - T 09-03-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 UA74_RS12810 2ba0a01a11de7655142ec633a9a9de34 422 Gene3D G3DSA:2.102.10.10 54 163 1.7E-23 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS06545 7c759f07bfe53263d5577d4985c011e2 358 SUPERFAMILY SSF52402 1 238 2.03E-43 T 09-03-2017 UA74_RS06545 7c759f07bfe53263d5577d4985c011e2 358 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 355 33.714 T 09-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 UA74_RS06545 7c759f07bfe53263d5577d4985c011e2 358 Gene3D G3DSA:2.30.30.280 207 268 2.1E-11 T 09-03-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 UA74_RS06545 7c759f07bfe53263d5577d4985c011e2 358 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 353 3.4E-83 T 09-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 UA74_RS06545 7c759f07bfe53263d5577d4985c011e2 358 Gene3D G3DSA:2.40.30.10 273 357 1.9E-15 T 09-03-2017 UA74_RS06545 7c759f07bfe53263d5577d4985c011e2 358 Pfam PF03054 tRNA methyl transferase 1 353 4.0E-110 T 09-03-2017 UA74_RS06545 7c759f07bfe53263d5577d4985c011e2 358 Gene3D G3DSA:3.40.50.620 1 204 1.1E-76 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS11465 d7c7afd0a5e501a02eb8d43345999363 226 SMART SM00422 7 70 6.9E-15 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS11465 d7c7afd0a5e501a02eb8d43345999363 226 SUPERFAMILY SSF46955 8 69 2.7E-12 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS11465 d7c7afd0a5e501a02eb8d43345999363 226 Gene3D G3DSA:1.10.1660.10 8 74 5.2E-17 T 09-03-2017 UA74_RS11465 d7c7afd0a5e501a02eb8d43345999363 226 Pfam PF00376 MerR family regulatory protein 7 38 4.6E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 SUPERFAMILY SSF53187 304 400 3.69E-54 T 09-03-2017 UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 SUPERFAMILY SSF53187 36 203 3.69E-54 T 09-03-2017 UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 Gene3D G3DSA:3.30.70.360 190 296 1.1E-26 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 SUPERFAMILY SSF55031 188 298 6.15E-24 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 42 367 7.2E-72 T 09-03-2017 IPR017439 Amidohydrolase GO:0016787 UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 Pfam PF07687 Peptidase dimerisation domain 191 283 8.8E-10 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 Gene3D G3DSA:3.40.630.10 301 411 2.0E-61 T 09-03-2017 UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 Gene3D G3DSA:3.40.630.10 24 189 2.0E-61 T 09-03-2017 UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 PIRSF PIRSF037226 22 416 3.0E-122 T 09-03-2017 IPR017144 Peptidase M20A, amidohydrolase, predicted UA74_RS30055 01b06aa0e50b69c8ad5dda878447d998 424 Pfam PF01546 Peptidase family M20/M25/M40 108 223 9.3E-6 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 Pfam PF00072 Response regulator receiver domain 5 119 1.1E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 SMART SM00448 3 118 9.5E-31 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 Gene3D G3DSA:1.10.10.10 126 215 2.1E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 SMART SM00421 152 209 4.0E-22 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 209 7.1E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 SUPERFAMILY SSF52172 1 134 8.4E-32 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 Gene3D G3DSA:3.40.50.2300 1 125 1.2E-34 T 09-03-2017 UA74_RS29690 df04aaae5ee90a9517f6b6208637c5e8 218 SUPERFAMILY SSF46894 145 214 5.1E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 498 2.8E-84 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 Gene3D G3DSA:1.20.1250.20 272 433 1.3E-19 T 09-03-2017 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 Gene3D G3DSA:1.20.1250.20 480 505 1.3E-19 T 09-03-2017 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 Gene3D G3DSA:1.20.1250.20 23 203 1.2E-33 T 09-03-2017 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 SUPERFAMILY SSF46785 535 650 6.81E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 SUPERFAMILY SSF103473 474 502 8.76E-31 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 SUPERFAMILY SSF103473 210 427 8.76E-31 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 Pfam PF07690 Major Facilitator Superfamily 25 417 2.6E-53 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 PRINTS PR01035 Tetracycline resistance protein signature 145 167 3.1E-5 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 PRINTS PR01035 Tetracycline resistance protein signature 31 47 3.1E-5 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 Gene3D G3DSA:1.10.10.10 533 650 2.1E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04945 b27d21ad4c04edc57a4efef831a7fb6b 669 SUPERFAMILY SSF103473 11 195 6.54E-45 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS10030 5191584539d9506783dd47ef923ac845 243 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 243 9.7E-122 T 09-03-2017 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 UA74_RS10030 5191584539d9506783dd47ef923ac845 243 Pfam PF00977 Histidine biosynthesis protein 5 234 8.0E-60 T 09-03-2017 IPR006062 Histidine biosynthesis GO:0000105 UA74_RS10030 5191584539d9506783dd47ef923ac845 243 Gene3D G3DSA:3.20.20.70 5 241 2.5E-68 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS10030 5191584539d9506783dd47ef923ac845 243 SUPERFAMILY SSF51366 3 240 5.81E-58 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 UA74_RS10030 5191584539d9506783dd47ef923ac845 243 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 241 31.733 T 09-03-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SMART SM00963 1 86 5.1E-33 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.9E-20 T 09-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Pfam PF02978 Signal peptide binding domain 330 427 1.8E-28 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SMART SM00382 99 303 1.4E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Gene3D G3DSA:1.10.260.30 330 431 4.0E-35 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 4.4E-177 T 09-03-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Gene3D G3DSA:1.20.120.140 2 89 8.4E-34 T 09-03-2017 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SMART SM00962 100 298 1.2E-109 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SUPERFAMILY SSF52540 42 356 7.3E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SUPERFAMILY SSF47446 330 430 8.67E-32 T 09-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 440 33.338 T 09-03-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 1.7E-69 T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Gene3D G3DSA:3.40.50.300 93 299 1.4E-76 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08905 9b4457e6ba0aaaf6d1dedfbdab00338d 526 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 09-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 Gene3D G3DSA:2.40.30.10 163 212 5.8E-12 T 09-03-2017 UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 Gene3D G3DSA:2.40.30.10 8 37 5.8E-12 T 09-03-2017 UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 Pfam PF00297 Ribosomal protein L3 99 186 9.7E-18 T 09-03-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 209 2.7E-88 T 09-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 212 39.579 T 09-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 SUPERFAMILY SSF50447 6 213 1.06E-81 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 09-03-2017 IPR019926 Ribosomal protein L3, conserved site UA74_RS02930 634cfbb2e48a2da96948738786f499fc 216 Gene3D G3DSA:4.10.960.10 81 162 2.6E-34 T 09-03-2017 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 Gene3D G3DSA:3.20.70.20 83 496 6.3E-99 T 09-03-2017 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 Gene3D G3DSA:3.20.70.20 668 713 6.3E-99 T 09-03-2017 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 Gene3D G3DSA:3.20.70.20 555 601 6.3E-99 T 09-03-2017 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 555 582 3.6E-12 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 410 433 3.6E-12 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 448 470 3.6E-12 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 249 268 3.6E-12 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 3.6E-12 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 SUPERFAMILY SSF51998 642 721 1.37E-129 T 09-03-2017 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 SUPERFAMILY SSF51998 174 607 1.37E-129 T 09-03-2017 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 93 719 1.1E-182 T 09-03-2017 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 Pfam PF02867 Ribonucleotide reductase, barrel domain 174 709 1.0E-141 T 09-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_RS08750 41a958fda890b352d502b824b8d93263 957 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 70 153 3.6E-19 T 09-03-2017 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 SMART SM00028 73 104 240.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 SMART SM00028 142 175 330.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 SMART SM00028 3 36 82.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 SMART SM00028 37 70 3.2 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 Pfam PF13432 Tetratricopeptide repeat 120 176 2.7E-7 T 09-03-2017 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 SUPERFAMILY SSF48452 3 170 8.49E-25 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 Pfam PF14559 Tetratricopeptide repeat 15 69 5.1E-6 T 09-03-2017 UA74_RS06815 c4e135003e0f72b2b686aaf30e1ea218 425 Gene3D G3DSA:1.25.40.10 2 176 4.2E-28 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 SUPERFAMILY SSF49503 145 214 4.03E-23 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 SUPERFAMILY SSF49503 39 105 4.03E-23 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 Gene3D G3DSA:2.60.40.420 148 216 2.8E-25 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 Gene3D G3DSA:2.60.40.420 38 108 2.8E-25 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 SUPERFAMILY SSF49503 217 320 1.44E-30 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 SUPERFAMILY SSF49503 536 589 1.44E-30 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 ProSitePatterns PS00080 Multicopper oxidases signature 2. 566 577 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 Gene3D G3DSA:2.60.40.420 217 350 4.7E-22 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 Pfam PF07732 Multicopper oxidase 71 107 4.5E-5 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 Pfam PF07732 Multicopper oxidase 144 213 3.2E-7 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 Gene3D G3DSA:2.60.40.420 464 586 5.5E-26 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 Pfam PF07731 Multicopper oxidase 466 586 3.0E-21 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_RS11540 1572e505665077cfd4f48f4f33e28b5d 614 ProSitePatterns PS00079 Multicopper oxidases signature 1. 561 581 - T 09-03-2017 IPR033138 Multicopper oxidases, conserved site UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 SUPERFAMILY SSF46894 148 220 1.7E-21 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 2.9E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 2.9E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 2.9E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 SMART SM00448 6 121 3.0E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 Gene3D G3DSA:1.10.10.10 129 221 3.6E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 1.6E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 Gene3D G3DSA:3.40.50.2300 3 128 5.6E-36 T 09-03-2017 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 SUPERFAMILY SSF52172 5 137 3.84E-32 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 SMART SM00421 158 215 6.8E-25 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS17855 0632c5396ef4ff27ba9621bf9e92c485 224 Pfam PF00072 Response regulator receiver domain 8 122 3.3E-24 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 Gene3D G3DSA:1.10.10.10 161 218 7.8E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 3.4E-16 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 Gene3D G3DSA:3.40.50.2300 3 160 2.0E-36 T 09-03-2017 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 SMART SM00448 5 122 2.9E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 SUPERFAMILY SSF52172 4 140 4.13E-31 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 SUPERFAMILY SSF46894 144 218 1.22E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 SMART SM00421 159 216 9.1E-24 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 Pfam PF00072 Response regulator receiver domain 7 123 9.9E-24 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.7E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.7E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS16465 65b3cd1fe2cfcf630a630de67f7a27d3 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.7E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28590 250765e10233b7205b97471d6e82383a 366 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 149 9.3E-29 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28590 250765e10233b7205b97471d6e82383a 366 Pfam PF02391 MoaE protein 236 346 5.0E-29 T 09-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28590 250765e10233b7205b97471d6e82383a 366 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 09-03-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 UA74_RS28590 250765e10233b7205b97471d6e82383a 366 SUPERFAMILY SSF54690 236 364 1.15E-33 T 09-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28590 250765e10233b7205b97471d6e82383a 366 SUPERFAMILY SSF53218 13 161 4.32E-36 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28590 250765e10233b7205b97471d6e82383a 366 Pfam PF00994 Probable molybdopterin binding domain 15 151 5.6E-25 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28590 250765e10233b7205b97471d6e82383a 366 Gene3D G3DSA:3.40.980.10 12 162 1.0E-45 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS28590 250765e10233b7205b97471d6e82383a 366 Gene3D G3DSA:3.90.1170.40 229 364 1.4E-38 T 09-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_RS28590 250765e10233b7205b97471d6e82383a 366 SMART SM00852 14 156 2.1E-15 T 09-03-2017 IPR001453 MoaB/Mog domain UA74_RS00725 912e2f2d350cf5b28a7c59a79c1b0e45 407 SUPERFAMILY SSF56219 212 402 3.31E-22 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS00725 912e2f2d350cf5b28a7c59a79c1b0e45 407 SUPERFAMILY SSF56219 41 184 3.31E-22 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS00725 912e2f2d350cf5b28a7c59a79c1b0e45 407 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 43 395 2.8E-39 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS07710 a7d5fa6b4e6d412bdda546183bcaca6a 107 Gene3D G3DSA:3.30.750.24 11 101 5.6E-16 T 09-03-2017 IPR002645 STAS domain UA74_RS07710 a7d5fa6b4e6d412bdda546183bcaca6a 107 SUPERFAMILY SSF52091 10 101 1.24E-14 T 09-03-2017 IPR002645 STAS domain UA74_RS07710 a7d5fa6b4e6d412bdda546183bcaca6a 107 Pfam PF01740 STAS domain 19 101 1.4E-10 T 09-03-2017 IPR002645 STAS domain UA74_RS07710 a7d5fa6b4e6d412bdda546183bcaca6a 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 102 1.3E-15 T 09-03-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UA74_RS25300 2d9c1bdc28e189c1d3dffcc0956f40fc 1280 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1055 1216 1.4E-13 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS25300 2d9c1bdc28e189c1d3dffcc0956f40fc 1280 SUPERFAMILY SSF53335 1000 1242 5.12E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS25300 2d9c1bdc28e189c1d3dffcc0956f40fc 1280 Pfam PF05050 Methyltransferase FkbM domain 1058 1241 2.1E-8 T 09-03-2017 IPR006342 Methyltransferase FkbM UA74_RS25300 2d9c1bdc28e189c1d3dffcc0956f40fc 1280 SUPERFAMILY SSF53756 528 771 1.76E-13 T 09-03-2017 UA74_RS25300 2d9c1bdc28e189c1d3dffcc0956f40fc 1280 Gene3D G3DSA:3.40.50.150 1038 1244 4.5E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS27155 ca1a0ce55ccc6f2280fda707174b7bae 203 Pfam PF12079 Protein of unknown function (DUF3558) 21 197 9.3E-28 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS06280 785cb4e293b7f216216e0c00e5068d06 195 Gene3D G3DSA:1.10.357.10 15 187 8.8E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06280 785cb4e293b7f216216e0c00e5068d06 195 SUPERFAMILY SSF48498 82 183 1.06E-13 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS06280 785cb4e293b7f216216e0c00e5068d06 195 SUPERFAMILY SSF46689 14 82 4.82E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06280 785cb4e293b7f216216e0c00e5068d06 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.7E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06280 785cb4e293b7f216216e0c00e5068d06 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.7E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06280 785cb4e293b7f216216e0c00e5068d06 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 2.2E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22910 59137390bad494f275962703ad80ac94 337 Gene3D G3DSA:3.40.47.10 173 337 9.4E-44 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22910 59137390bad494f275962703ad80ac94 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 250 337 1.1E-26 T 09-03-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS22910 59137390bad494f275962703ad80ac94 337 Gene3D G3DSA:3.40.47.10 21 172 2.8E-53 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS22910 59137390bad494f275962703ad80ac94 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 121 193 5.7E-21 T 09-03-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS22910 59137390bad494f275962703ad80ac94 337 SUPERFAMILY SSF53901 16 337 5.47E-54 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS09235 0d92199a020d1feaa78f62020981f32b 385 Gene3D G3DSA:3.90.1150.10 262 371 1.4E-12 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS09235 0d92199a020d1feaa78f62020981f32b 385 SUPERFAMILY SSF53383 20 371 1.34E-92 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS09235 0d92199a020d1feaa78f62020981f32b 385 Gene3D G3DSA:3.40.640.10 46 261 1.9E-79 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS09235 0d92199a020d1feaa78f62020981f32b 385 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 09-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 UA74_RS09235 0d92199a020d1feaa78f62020981f32b 385 Pfam PF00155 Aminotransferase class I and II 29 369 9.7E-56 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS24580 71f7885a69bce641a88451a059ad7385 244 Pfam PF12158 Protein of unknown function (DUF3592) 98 199 8.7E-6 T 09-03-2017 IPR021994 Protein of unknown function DUF3592 UA74_RS24950 93ed64080c0e5758b40a27f46cced500 174 Hamap MF_00977 3'-5' exoribonuclease. 1 159 42.873 T 09-03-2017 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 UA74_RS24950 93ed64080c0e5758b40a27f46cced500 174 Pfam PF16473 3' exoribonuclease, RNase T-like 2 155 2.1E-18 T 09-03-2017 IPR033390 3'-5' exoribonuclease Rv2179c-like domain UA74_RS24950 93ed64080c0e5758b40a27f46cced500 174 SUPERFAMILY SSF53098 4 154 2.88E-6 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS20780 140d82bd7483655f022ed64438ee0780 391 SUPERFAMILY SSF53822 91 365 1.36E-38 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS20780 140d82bd7483655f022ed64438ee0780 391 Gene3D G3DSA:3.40.50.2300 208 350 2.2E-19 T 09-03-2017 UA74_RS20780 140d82bd7483655f022ed64438ee0780 391 Pfam PF13407 Periplasmic binding protein domain 122 343 8.1E-27 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS20780 140d82bd7483655f022ed64438ee0780 391 Gene3D G3DSA:3.40.50.2300 126 207 2.8E-11 T 09-03-2017 UA74_RS29320 663f8a7b16b2e5c0705943884400e193 101 SUPERFAMILY SSF49478 26 78 5.49E-6 T 09-03-2017 UA74_RS29320 663f8a7b16b2e5c0705943884400e193 101 Pfam PF07210 Protein of unknown function (DUF1416) 4 99 2.1E-35 T 09-03-2017 IPR010814 Protein of unknown function DUF1416 UA74_RS29320 663f8a7b16b2e5c0705943884400e193 101 Gene3D G3DSA:2.60.40.10 25 84 3.3E-7 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS09060 accdca4c0077c86d34acf74806544b66 253 SUPERFAMILY SSF53335 27 202 1.66E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09060 accdca4c0077c86d34acf74806544b66 253 Pfam PF08241 Methyltransferase domain 58 152 1.3E-17 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS09060 accdca4c0077c86d34acf74806544b66 253 Gene3D G3DSA:3.40.50.150 48 199 7.8E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06955 5f53f9e95cb96ac971b2d08e76e930ed 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.9E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06955 5f53f9e95cb96ac971b2d08e76e930ed 189 SUPERFAMILY SSF48498 85 188 3.89E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS06955 5f53f9e95cb96ac971b2d08e76e930ed 189 SUPERFAMILY SSF46689 8 75 1.9E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06955 5f53f9e95cb96ac971b2d08e76e930ed 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.8E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06955 5f53f9e95cb96ac971b2d08e76e930ed 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.8E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06955 5f53f9e95cb96ac971b2d08e76e930ed 189 Gene3D G3DSA:1.10.357.10 6 188 2.0E-34 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS16905 a739deb0107ba37f8160a13e02c5cc13 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.5E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS16905 a739deb0107ba37f8160a13e02c5cc13 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.5E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS16905 a739deb0107ba37f8160a13e02c5cc13 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 2.4E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS16905 a739deb0107ba37f8160a13e02c5cc13 208 SUPERFAMILY SSF48498 87 194 4.45E-12 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS16905 a739deb0107ba37f8160a13e02c5cc13 208 Gene3D G3DSA:1.10.357.10 17 189 2.4E-30 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS16905 a739deb0107ba37f8160a13e02c5cc13 208 SUPERFAMILY SSF46689 10 85 5.64E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS29435 698c9e1947de3c9f0db0585759058527 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 1.8E-25 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29435 698c9e1947de3c9f0db0585759058527 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 1.0E-21 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29435 698c9e1947de3c9f0db0585759058527 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 75 3.0E-15 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29435 698c9e1947de3c9f0db0585759058527 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 19.962 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS29435 698c9e1947de3c9f0db0585759058527 79 SUPERFAMILY SSF82697 3 77 7.5E-23 T 09-03-2017 UA74_RS29435 698c9e1947de3c9f0db0585759058527 79 Gene3D G3DSA:3.30.1280.10 3 78 1.2E-29 T 09-03-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_RS24720 f61761d499f7ada116049473b52dfc3f 341 Gene3D G3DSA:3.20.20.70 4 328 2.8E-55 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS24720 f61761d499f7ada116049473b52dfc3f 341 SUPERFAMILY SSF51412 4 331 3.21E-48 T 09-03-2017 UA74_RS24720 f61761d499f7ada116049473b52dfc3f 341 Pfam PF03060 Nitronate monooxygenase 7 331 8.4E-76 T 09-03-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 UA74_RS06595 327dc7b6615ec87094cbf1ce6b6e4b43 72 SUPERFAMILY SSF160582 1 56 3.66E-14 T 09-03-2017 UA74_RS06595 327dc7b6615ec87094cbf1ce6b6e4b43 72 Pfam PF03621 MbtH-like protein 1 51 4.2E-13 T 09-03-2017 IPR005153 MbtH-like protein UA74_RS06595 327dc7b6615ec87094cbf1ce6b6e4b43 72 Gene3D G3DSA:3.90.820.10 13 56 3.7E-12 T 09-03-2017 UA74_RS06595 327dc7b6615ec87094cbf1ce6b6e4b43 72 SMART SM00923 3 53 1.2E-5 T 09-03-2017 IPR005153 MbtH-like protein UA74_RS00835 d79f618ee05bd414ff4fd9c9ed92f8d0 162 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 10 153 5.0E-50 T 09-03-2017 IPR023869 tRNA adenosine deaminase-associated protein, putative UA74_RS18270 da94a25eeae130dbeb2efccb9397f7af 376 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 206 8.0E-30 T 09-03-2017 UA74_RS18270 da94a25eeae130dbeb2efccb9397f7af 376 Gene3D G3DSA:3.40.50.150 17 244 2.9E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS18270 da94a25eeae130dbeb2efccb9397f7af 376 SUPERFAMILY SSF53335 6 207 3.31E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12135 10c0f0681bd469cbad01171bee7c731f 178 Pfam PF03652 Holliday junction resolvase 28 161 2.0E-41 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UA74_RS12135 10c0f0681bd469cbad01171bee7c731f 178 SMART SM00732 27 129 6.2E-21 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 UA74_RS12135 10c0f0681bd469cbad01171bee7c731f 178 Gene3D G3DSA:3.30.420.140 27 168 5.6E-44 T 09-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 UA74_RS12135 10c0f0681bd469cbad01171bee7c731f 178 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 27 164 21.948 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UA74_RS12135 10c0f0681bd469cbad01171bee7c731f 178 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 30 161 4.7E-26 T 09-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UA74_RS12135 10c0f0681bd469cbad01171bee7c731f 178 SUPERFAMILY SSF53098 27 163 3.19E-32 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS05245 081aee843a0644fc02119c7fe2e73d3c 349 SUPERFAMILY SSF53335 142 236 2.05E-17 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05245 081aee843a0644fc02119c7fe2e73d3c 349 Pfam PF05175 Methyltransferase small domain 162 235 2.2E-8 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 UA74_RS05245 081aee843a0644fc02119c7fe2e73d3c 349 Gene3D G3DSA:3.40.50.150 144 241 1.3E-14 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13735 6d80ab1b72aa563e598eb16a661de304 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 327 9.3E-25 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 28 42 - T 09-03-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 SUPERFAMILY SSF51445 24 473 9.24E-154 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 TIGRFAM TIGR03356 BGL: beta-galactosidase 24 463 9.9E-174 T 09-03-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 Pfam PF00232 Glycosyl hydrolase family 1 23 470 1.8E-147 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 Gene3D G3DSA:3.20.20.80 24 475 2.9E-145 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 8.2E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 407 8.2E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 8.2E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 383 8.2E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS06850 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 8.2E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS06470 64b961635841a695c93f679128d81f0e 239 SUPERFAMILY SSF51161 33 219 1.03E-29 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS06470 64b961635841a695c93f679128d81f0e 239 Gene3D G3DSA:2.160.10.10 32 216 1.5E-32 T 09-03-2017 UA74_RS06470 64b961635841a695c93f679128d81f0e 239 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 162 196 3.8E-7 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS28895 a6188e9937768f0d60d5253d3ceb3155 236 Gene3D G3DSA:2.60.120.590 13 214 2.8E-51 T 09-03-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like UA74_RS28895 a6188e9937768f0d60d5253d3ceb3155 236 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 15 213 1.7E-47 T 09-03-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like UA74_RS28895 a6188e9937768f0d60d5253d3ceb3155 236 SUPERFAMILY SSF51197 13 214 2.33E-44 T 09-03-2017 UA74_RS09785 2d8344585ddcafa048069447a7f3d428 248 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 20 245 2.3E-40 T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 UA74_RS09785 2d8344585ddcafa048069447a7f3d428 248 PIRSF PIRSF004848 7 248 3.7E-59 T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 UA74_RS09785 2d8344585ddcafa048069447a7f3d428 248 SUPERFAMILY SSF51419 16 243 1.07E-60 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS09785 2d8344585ddcafa048069447a7f3d428 248 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 92 106 - T 09-03-2017 IPR011078 Uncharacterised protein family UPF0001 UA74_RS09785 2d8344585ddcafa048069447a7f3d428 248 Pfam PF01168 Alanine racemase, N-terminal domain 20 246 1.5E-19 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS09785 2d8344585ddcafa048069447a7f3d428 248 Gene3D G3DSA:3.20.20.10 9 246 1.4E-74 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS10045 7893b839bf572e11356faae31eb0edda 358 Pfam PF01757 Acyltransferase family 1 333 6.2E-11 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 SUPERFAMILY SSF55424 357 471 3.78E-26 T 09-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PIRSF PIRSF000350 1 470 4.2E-76 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 SUPERFAMILY SSF51905 4 336 9.72E-45 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 361 466 2.1E-20 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 1.2E-20 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.2E-20 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.2E-20 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 1.2E-20 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 318 6.4E-50 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 Gene3D G3DSA:3.30.390.30 356 472 3.2E-26 T 09-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 1.5E-51 T 09-03-2017 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 Gene3D G3DSA:3.50.50.60 5 147 1.4E-29 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25625 077fab39a07eae00a6ee751ee9b2b7af 475 Gene3D G3DSA:3.50.50.60 148 335 1.4E-39 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS18430 0b976ded56a5daaf9f32d7ee5737fa25 289 Gene3D G3DSA:3.20.20.100 19 285 1.2E-72 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS18430 0b976ded56a5daaf9f32d7ee5737fa25 289 SUPERFAMILY SSF51430 17 284 2.88E-75 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS18430 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 119 137 1.3E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS18430 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 150 167 1.3E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS18430 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 221 245 1.3E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS18430 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 54 78 1.3E-6 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS18430 0b976ded56a5daaf9f32d7ee5737fa25 289 Pfam PF00248 Aldo/keto reductase family 24 284 8.5E-61 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS03125 2d96aece4754d17f11eb5dc2f8bc37f7 135 SUPERFAMILY SSF53137 20 135 3.2E-49 T 09-03-2017 UA74_RS03125 2d96aece4754d17f11eb5dc2f8bc37f7 135 Gene3D G3DSA:3.30.420.80 13 135 9.7E-57 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UA74_RS03125 2d96aece4754d17f11eb5dc2f8bc37f7 135 PIRSF PIRSF002131 6 135 2.1E-53 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UA74_RS03125 2d96aece4754d17f11eb5dc2f8bc37f7 135 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 16 132 1.5E-58 T 09-03-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS03125 2d96aece4754d17f11eb5dc2f8bc37f7 135 ProSitePatterns PS00054 Ribosomal protein S11 signature. 103 125 - T 09-03-2017 IPR018102 Ribosomal S11, conserved site UA74_RS03125 2d96aece4754d17f11eb5dc2f8bc37f7 135 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 135 33.96 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UA74_RS03125 2d96aece4754d17f11eb5dc2f8bc37f7 135 Pfam PF00411 Ribosomal protein S11 25 134 1.0E-48 T 09-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UA74_RS11330 561d3155fa6ab6fcc7578f8966149766 242 SUPERFAMILY SSF51735 2 194 1.19E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11330 561d3155fa6ab6fcc7578f8966149766 242 Gene3D G3DSA:3.40.50.720 2 184 3.3E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11330 561d3155fa6ab6fcc7578f8966149766 242 Pfam PF00106 short chain dehydrogenase 3 183 4.0E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 Pfam PF00561 alpha/beta hydrolase fold 22 253 2.4E-27 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.4E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.4E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.4E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00412 Epoxide hydrolase signature 27 45 6.2E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00412 Epoxide hydrolase signature 47 62 6.2E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00412 Epoxide hydrolase signature 214 230 6.2E-6 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 SUPERFAMILY SSF53474 2 274 1.17E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15295 c410682bf38a26e7d20b409cbf7862a5 275 Gene3D G3DSA:3.40.50.1820 2 274 6.0E-68 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05470 d4900dd3487559f99b3cb1e821afc833 185 SUPERFAMILY SSF46689 3 67 8.98E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05470 d4900dd3487559f99b3cb1e821afc833 185 SUPERFAMILY SSF48498 79 178 3.86E-11 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS05470 d4900dd3487559f99b3cb1e821afc833 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.4E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05470 d4900dd3487559f99b3cb1e821afc833 185 Pfam PF13305 WHG domain 80 160 2.0E-7 T 09-03-2017 IPR025996 WHG domain UA74_RS05470 d4900dd3487559f99b3cb1e821afc833 185 Gene3D G3DSA:1.10.357.10 4 179 5.7E-32 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS05470 d4900dd3487559f99b3cb1e821afc833 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 7.6E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05470 d4900dd3487559f99b3cb1e821afc833 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 7.6E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13120 0f5b5d0028f7be74ff412ad1a726dee0 201 SUPERFAMILY SSF88946 19 115 3.92E-22 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13120 0f5b5d0028f7be74ff412ad1a726dee0 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 191 5.2E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13120 0f5b5d0028f7be74ff412ad1a726dee0 201 Gene3D G3DSA:1.10.10.10 134 194 2.5E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13120 0f5b5d0028f7be74ff412ad1a726dee0 201 Pfam PF08281 Sigma-70, region 4 137 188 6.1E-15 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13120 0f5b5d0028f7be74ff412ad1a726dee0 201 SUPERFAMILY SSF88659 133 193 6.76E-13 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13120 0f5b5d0028f7be74ff412ad1a726dee0 201 Pfam PF04542 Sigma-70 region 2 39 104 2.1E-13 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS13120 0f5b5d0028f7be74ff412ad1a726dee0 201 Gene3D G3DSA:1.10.1740.10 22 120 1.6E-23 T 09-03-2017 UA74_RS13210 7155c94df5f522dec0e7aee396997759 222 Gene3D G3DSA:1.10.357.10 8 193 5.4E-43 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS13210 7155c94df5f522dec0e7aee396997759 222 SUPERFAMILY SSF48498 83 186 4.79E-18 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS13210 7155c94df5f522dec0e7aee396997759 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.7E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13210 7155c94df5f522dec0e7aee396997759 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.7E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13210 7155c94df5f522dec0e7aee396997759 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 8.3E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13210 7155c94df5f522dec0e7aee396997759 222 SUPERFAMILY SSF46689 5 84 1.55E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 Gene3D G3DSA:3.40.50.1820 13 277 2.4E-65 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 6.3E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 6.3E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 6.3E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 6.3E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 6.5E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 6.5E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 6.5E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 SUPERFAMILY SSF53474 13 277 2.11E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19430 9ca61f4f659d6e40e535c300ba49b1c6 278 Pfam PF00561 alpha/beta hydrolase fold 26 264 5.2E-32 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS21785 3366cc0fa41cc8b1d0f657581af6af79 225 Pfam PF00753 Metallo-beta-lactamase superfamily 34 204 6.3E-16 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS21785 3366cc0fa41cc8b1d0f657581af6af79 225 Gene3D G3DSA:3.60.15.10 20 223 4.0E-47 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS21785 3366cc0fa41cc8b1d0f657581af6af79 225 SUPERFAMILY SSF56281 27 221 1.96E-46 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS21785 3366cc0fa41cc8b1d0f657581af6af79 225 SMART SM00849 36 204 1.4E-30 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 10 179 30.135 T 09-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 16 179 3.1E-62 T 09-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 Gene3D G3DSA:3.10.20.80 12 86 4.4E-36 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 ProSitePatterns PS00938 Initiation factor 3 signature. 67 80 - T 09-03-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 SUPERFAMILY SSF55200 94 178 1.7E-30 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 93 176 3.6E-33 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 SUPERFAMILY SSF54364 14 87 3.27E-29 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 Gene3D G3DSA:3.30.110.10 88 179 1.4E-36 T 09-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 UA74_RS21760 481bf1466e20eff48e92061efbbc8af7 203 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 16 84 5.8E-31 T 09-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_RS22280 3ac80da70db735e434b437c8a4544b8f 268 Gene3D G3DSA:3.40.50.1820 2 259 3.8E-51 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22280 3ac80da70db735e434b437c8a4544b8f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 7.8E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22280 3ac80da70db735e434b437c8a4544b8f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 7.8E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22280 3ac80da70db735e434b437c8a4544b8f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 7.8E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22280 3ac80da70db735e434b437c8a4544b8f 268 Pfam PF00561 alpha/beta hydrolase fold 20 128 1.4E-20 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS22280 3ac80da70db735e434b437c8a4544b8f 268 SUPERFAMILY SSF53474 1 259 1.08E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15550 eca2c5a1e50f2914c4a3821b37f475f7 196 Gene3D G3DSA:1.10.357.10 14 195 3.6E-40 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15550 eca2c5a1e50f2914c4a3821b37f475f7 196 SUPERFAMILY SSF48498 92 195 1.08E-10 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS15550 eca2c5a1e50f2914c4a3821b37f475f7 196 SUPERFAMILY SSF46689 13 93 1.15E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15550 eca2c5a1e50f2914c4a3821b37f475f7 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.2E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15550 eca2c5a1e50f2914c4a3821b37f475f7 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.2E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15550 eca2c5a1e50f2914c4a3821b37f475f7 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 1.6E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 Gene3D G3DSA:1.10.10.10 3 85 7.5E-36 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 Gene3D G3DSA:3.30.450.40 177 338 3.9E-36 T 09-03-2017 IPR029016 GAF domain-like UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 PIRSF PIRSF005485 1 340 5.7E-101 T 09-03-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 330 27.53 T 09-03-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 Pfam PF01628 HrcA protein C terminal domain 104 323 8.3E-61 T 09-03-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 Pfam PF08220 DeoR-like helix-turn-helix domain 17 63 3.1E-5 T 09-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 SUPERFAMILY SSF46785 4 83 1.21E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 SUPERFAMILY SSF55781 72 338 5.3E-56 T 09-03-2017 IPR029016 GAF domain-like UA74_RS24620 d2d1e309b05d544560626acfe6f4520e 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 336 6.3E-93 T 09-03-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UA74_RS15130 6e04c4a42d9847f08d5eea9a9e4af1b1 136 Pfam PF01638 HxlR-like helix-turn-helix 36 121 4.4E-24 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS15130 6e04c4a42d9847f08d5eea9a9e4af1b1 136 SUPERFAMILY SSF46785 20 122 6.0E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15130 6e04c4a42d9847f08d5eea9a9e4af1b1 136 Gene3D G3DSA:1.10.10.10 21 134 1.6E-37 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29405 db9cdd14b2b2a0d66b6f1cd128757ede 653 Gene3D G3DSA:1.50.10.10 244 630 4.4E-78 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS29405 db9cdd14b2b2a0d66b6f1cd128757ede 653 SUPERFAMILY SSF48208 234 617 1.49E-97 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS29405 db9cdd14b2b2a0d66b6f1cd128757ede 653 Pfam PF00723 Glycosyl hydrolases family 15 252 613 6.2E-52 T 09-03-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 UA74_RS25795 d7d11113d301ce82b02c57117581e8bf 196 Gene3D G3DSA:3.40.50.150 2 182 1.2E-52 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS25795 d7d11113d301ce82b02c57117581e8bf 196 Pfam PF03602 Conserved hypothetical protein 95 2 178 5.6E-47 T 09-03-2017 UA74_RS25795 d7d11113d301ce82b02c57117581e8bf 196 SUPERFAMILY SSF53335 2 179 2.04E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS25795 d7d11113d301ce82b02c57117581e8bf 196 PIRSF PIRSF004553 1 183 1.5E-53 T 09-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS25795 d7d11113d301ce82b02c57117581e8bf 196 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 178 8.7E-47 T 09-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 UA74_RS25795 d7d11113d301ce82b02c57117581e8bf 196 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS02290 685b77e84a0bf509908b3ad3e05816d2 229 SMART SM00554 131 228 1.3E-27 T 09-03-2017 IPR000782 FAS1 domain UA74_RS02290 685b77e84a0bf509908b3ad3e05816d2 229 Pfam PF02469 Fasciclin domain 107 227 1.3E-27 T 09-03-2017 IPR000782 FAS1 domain UA74_RS02290 685b77e84a0bf509908b3ad3e05816d2 229 Gene3D G3DSA:2.30.180.10 95 227 1.4E-30 T 09-03-2017 IPR000782 FAS1 domain UA74_RS02290 685b77e84a0bf509908b3ad3e05816d2 229 SUPERFAMILY SSF82153 93 228 9.68E-30 T 09-03-2017 IPR000782 FAS1 domain UA74_RS12320 a72dcf6056a4c47ffa0028cd391daf87 96 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 21 93 14.491 T 09-03-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS12320 a72dcf6056a4c47ffa0028cd391daf87 96 Pfam PF01192 RNA polymerase Rpb6 28 90 1.2E-15 T 09-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 UA74_RS12320 a72dcf6056a4c47ffa0028cd391daf87 96 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 21 91 1.5E-25 T 09-03-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_RS12320 a72dcf6056a4c47ffa0028cd391daf87 96 SUPERFAMILY SSF63562 21 92 3.66E-23 T 09-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 UA74_RS12320 a72dcf6056a4c47ffa0028cd391daf87 96 SMART SM01409 28 92 1.3E-14 T 09-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 UA74_RS12320 a72dcf6056a4c47ffa0028cd391daf87 96 Gene3D G3DSA:3.90.940.10 21 94 1.6E-32 T 09-03-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 3.6E-16 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 SUPERFAMILY SSF47413 12 69 3.07E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 Gene3D G3DSA:1.10.260.40 11 66 6.6E-24 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 Gene3D G3DSA:3.40.50.2300 182 344 8.1E-61 T 09-03-2017 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 Gene3D G3DSA:3.40.50.2300 67 181 3.5E-22 T 09-03-2017 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 SMART SM00354 12 82 3.2E-23 T 09-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 Pfam PF13377 Periplasmic binding protein-like domain 185 344 3.5E-40 T 09-03-2017 UA74_RS21150 b43d834fd193360cb722a889d6986946 344 SUPERFAMILY SSF53822 86 344 1.58E-67 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS08070 39bdc7d6116270fb6710b17638d07a93 251 Gene3D G3DSA:3.90.1560.10 18 245 4.0E-51 T 09-03-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 UA74_RS08070 39bdc7d6116270fb6710b17638d07a93 251 Pfam PF04029 2-phosphosulpholactate phosphatase 29 241 9.8E-19 T 09-03-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 UA74_RS08070 39bdc7d6116270fb6710b17638d07a93 251 SUPERFAMILY SSF142823 13 244 3.66E-39 T 09-03-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 UA74_RS16570 59f61edfb0891fe5b6b18d7fe7c5fa04 338 Gene3D G3DSA:3.40.47.10 171 335 9.7E-42 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16570 59f61edfb0891fe5b6b18d7fe7c5fa04 338 SUPERFAMILY SSF53901 12 335 4.99E-60 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16570 59f61edfb0891fe5b6b18d7fe7c5fa04 338 Gene3D G3DSA:3.40.47.10 12 170 3.1E-55 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS16570 59f61edfb0891fe5b6b18d7fe7c5fa04 338 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 335 1.9E-88 T 09-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS16570 59f61edfb0891fe5b6b18d7fe7c5fa04 338 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 248 335 3.6E-26 T 09-03-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS16570 59f61edfb0891fe5b6b18d7fe7c5fa04 338 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 192 3.1E-22 T 09-03-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS01450 e9c40591d76792ef2a17231f833844fe 727 Gene3D G3DSA:3.40.50.300 160 268 6.1E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01450 e9c40591d76792ef2a17231f833844fe 727 Gene3D G3DSA:3.40.50.300 479 587 6.1E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01450 e9c40591d76792ef2a17231f833844fe 727 Pfam PF13245 Part of AAA domain 176 234 7.0E-14 T 09-03-2017 UA74_RS01450 e9c40591d76792ef2a17231f833844fe 727 SUPERFAMILY SSF52540 334 363 9.39E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01450 e9c40591d76792ef2a17231f833844fe 727 SUPERFAMILY SSF52540 160 238 9.39E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01450 e9c40591d76792ef2a17231f833844fe 727 SUPERFAMILY SSF52540 483 704 9.39E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01450 e9c40591d76792ef2a17231f833844fe 727 Gene3D G3DSA:3.40.50.300 654 712 7.4E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 Pfam PF09278 MerR, DNA binding 51 116 6.5E-17 T 09-03-2017 IPR015358 Transcription regulator MerR, DNA binding UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 Gene3D G3DSA:1.10.1660.10 63 141 1.0E-15 T 09-03-2017 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 SMART SM00422 9 77 3.7E-25 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 Pfam PF00376 MerR family regulatory protein 10 46 4.8E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 Gene3D G3DSA:1.10.1660.10 7 62 9.6E-20 T 09-03-2017 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 146 1.1E-67 T 09-03-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 1.1E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 1.1E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 1.1E-13 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS14015 f641393413164c3837b31ed21f5c894b 146 SUPERFAMILY SSF46955 9 129 2.34E-26 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 SUPERFAMILY SSF54373 572 661 2.03E-18 T 09-03-2017 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 SUPERFAMILY SSF51905 105 509 1.36E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 SUPERFAMILY SSF51905 678 714 1.36E-48 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.90.660.10 134 215 1.4E-54 T 09-03-2017 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.90.660.10 575 655 1.4E-54 T 09-03-2017 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.90.660.10 490 509 1.4E-54 T 09-03-2017 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.50.50.60 681 714 7.3E-15 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.50.50.60 369 486 7.3E-15 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.50.50.60 103 133 7.6E-12 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:1.10.405.10 253 368 7.9E-15 T 09-03-2017 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Pfam PF01593 Flavin containing amine oxidoreductase 575 713 3.0E-18 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Pfam PF01593 Flavin containing amine oxidoreductase 115 198 1.9E-16 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS08615 717dba991f0317f2f3743db3afa7afbb 719 Pfam PF01593 Flavin containing amine oxidoreductase 367 504 4.7E-11 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 SMART SM00421 167 224 8.6E-25 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 SUPERFAMILY SSF52172 1 144 2.28E-29 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 Gene3D G3DSA:1.10.10.10 135 231 2.7E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 Pfam PF00196 Bacterial regulatory proteins, luxR family 169 223 1.0E-18 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 ProSitePatterns PS00622 LuxR-type HTH domain signature. 184 211 - T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 SMART SM00448 2 125 1.3E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 Gene3D G3DSA:3.40.50.2300 1 134 5.9E-35 T 09-03-2017 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 212 4.2E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 200 4.2E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 184 4.2E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 Pfam PF00072 Response regulator receiver domain 4 126 3.7E-21 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21550 d74a6440ccf831f415432f48bfe45b06 234 SUPERFAMILY SSF46894 161 230 2.24E-22 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS00870 e4e3da8d9330efb8c3bc867fc6cc124a 170 SMART SM00347 40 140 3.6E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00870 e4e3da8d9330efb8c3bc867fc6cc124a 170 SUPERFAMILY SSF46785 18 155 6.07E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00870 e4e3da8d9330efb8c3bc867fc6cc124a 170 Gene3D G3DSA:1.10.10.10 18 153 5.0E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00870 e4e3da8d9330efb8c3bc867fc6cc124a 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 1.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00870 e4e3da8d9330efb8c3bc867fc6cc124a 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 1.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00870 e4e3da8d9330efb8c3bc867fc6cc124a 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 1.2E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS00870 e4e3da8d9330efb8c3bc867fc6cc124a 170 Pfam PF13463 Winged helix DNA-binding domain 68 113 3.2E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 294 2.8E-20 T 09-03-2017 IPR020801 Polyketide synthase, acyl transferase domain UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 SUPERFAMILY SSF55048 124 190 1.57E-8 T 09-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 Pfam PF00698 Acyl transferase domain 4 266 1.1E-39 T 09-03-2017 IPR014043 Acyl transferase UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 PIRSF PIRSF000446 1 296 1.9E-62 T 09-03-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 SUPERFAMILY SSF52151 1 118 9.16E-58 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 SUPERFAMILY SSF52151 183 280 9.16E-58 T 09-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 Gene3D G3DSA:3.30.70.250 122 189 3.8E-11 T 09-03-2017 UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 Gene3D G3DSA:3.40.366.10 190 279 2.1E-53 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS05835 33d299909d953640d4bfb17368302ffc 300 Gene3D G3DSA:3.40.366.10 2 118 2.1E-53 T 09-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 UA74_RS12890 2e7d8435419b87fbbb7a157ecf14c189 87 SUPERFAMILY SSF101386 2 87 1.83E-20 T 09-03-2017 UA74_RS12890 2e7d8435419b87fbbb7a157ecf14c189 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.471 T 09-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 UA74_RS12890 2e7d8435419b87fbbb7a157ecf14c189 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 2.7E-21 T 09-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 UA74_RS12890 2e7d8435419b87fbbb7a157ecf14c189 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 11 86 2.7E-6 T 09-03-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 UA74_RS26735 1ccb3beeff84feac75bfce245ea36cae 586 Gene3D G3DSA:2.120.10.30 401 534 4.0E-4 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS26735 1ccb3beeff84feac75bfce245ea36cae 586 Gene3D G3DSA:2.120.10.30 311 367 4.0E-4 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS26735 1ccb3beeff84feac75bfce245ea36cae 586 SUPERFAMILY SSF69322 412 572 1.24E-5 T 09-03-2017 UA74_RS26735 1ccb3beeff84feac75bfce245ea36cae 586 SUPERFAMILY SSF69322 346 367 1.24E-5 T 09-03-2017 UA74_RS26735 1ccb3beeff84feac75bfce245ea36cae 586 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 334 585 3.8E-41 T 09-03-2017 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal UA74_RS26735 1ccb3beeff84feac75bfce245ea36cae 586 Pfam PF10646 Sporulation and spore germination 182 291 8.5E-9 T 09-03-2017 IPR019606 GerMN domain UA74_RS26735 1ccb3beeff84feac75bfce245ea36cae 586 SMART SM00909 209 297 2.5E-8 T 09-03-2017 IPR019606 GerMN domain UA74_RS02435 93d030a20312756e4ff793082ebb565d 367 Gene3D G3DSA:3.40.50.1100 151 342 3.4E-35 T 09-03-2017 UA74_RS02435 93d030a20312756e4ff793082ebb565d 367 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 322 6.0E-47 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS02435 93d030a20312756e4ff793082ebb565d 367 SUPERFAMILY SSF53686 30 342 6.16E-70 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS02435 93d030a20312756e4ff793082ebb565d 367 Gene3D G3DSA:3.40.50.1100 55 150 4.3E-23 T 09-03-2017 UA74_RS07975 11b816c8184f8c31f8eb30ed13ac7bdc 152 SUPERFAMILY SSF54637 4 136 4.41E-27 T 09-03-2017 IPR029069 HotDog domain UA74_RS07975 11b816c8184f8c31f8eb30ed13ac7bdc 152 Pfam PF13279 Thioesterase-like superfamily 11 122 1.7E-9 T 09-03-2017 UA74_RS07975 11b816c8184f8c31f8eb30ed13ac7bdc 152 Gene3D G3DSA:3.10.129.10 3 134 2.7E-35 T 09-03-2017 IPR029069 HotDog domain UA74_RS22035 9077619a54c58e096b1df72367eb5f7f 228 Pfam PF00881 Nitroreductase family 16 203 1.0E-28 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_RS22035 9077619a54c58e096b1df72367eb5f7f 228 SUPERFAMILY SSF55469 130 227 2.09E-35 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS22035 9077619a54c58e096b1df72367eb5f7f 228 SUPERFAMILY SSF55469 12 78 2.09E-35 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS22035 9077619a54c58e096b1df72367eb5f7f 228 Gene3D G3DSA:3.40.109.10 12 90 7.9E-39 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS22035 9077619a54c58e096b1df72367eb5f7f 228 Gene3D G3DSA:3.40.109.10 130 227 7.9E-39 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS01170 d8f59c8862821d72491bc6c531d15ffa 334 Gene3D G3DSA:3.40.50.300 34 240 4.9E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01170 d8f59c8862821d72491bc6c531d15ffa 334 SUPERFAMILY SSF52540 19 238 1.18E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01170 d8f59c8862821d72491bc6c531d15ffa 334 Gene3D G3DSA:3.40.50.300 246 279 4.4E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01170 d8f59c8862821d72491bc6c531d15ffa 334 Gene3D G3DSA:3.40.50.300 16 33 4.4E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01170 d8f59c8862821d72491bc6c531d15ffa 334 Pfam PF02374 Anion-transporting ATPase 19 176 4.5E-17 T 09-03-2017 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_RS29685 d38556e62d0badffaeeb2ba682864f50 466 Pfam PF00144 Beta-lactamase 26 329 1.9E-52 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS29685 d38556e62d0badffaeeb2ba682864f50 466 Gene3D G3DSA:3.40.710.10 32 344 1.7E-68 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS29685 d38556e62d0badffaeeb2ba682864f50 466 SUPERFAMILY SSF56601 21 341 2.05E-65 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS01915 f2b5300df71416d62021ff5f588cf058 277 Gene3D G3DSA:3.20.20.30 129 276 4.1E-11 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS01915 f2b5300df71416d62021ff5f588cf058 277 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 5 275 7.3E-107 T 09-03-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted UA74_RS01915 f2b5300df71416d62021ff5f588cf058 277 Gene3D G3DSA:3.20.20.30 18 116 4.0E-7 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS01915 f2b5300df71416d62021ff5f588cf058 277 Pfam PF00296 Luciferase-like monooxygenase 18 115 1.5E-5 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS01915 f2b5300df71416d62021ff5f588cf058 277 SUPERFAMILY SSF51679 15 274 2.52E-27 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS05270 f9c8fb4cff03fc430afbf120c516d019 551 Pfam PF00668 Condensation domain 7 307 5.9E-47 T 09-03-2017 IPR001242 Condensation domain UA74_RS05270 f9c8fb4cff03fc430afbf120c516d019 551 Pfam PF00550 Phosphopantetheine attachment site 485 547 5.4E-10 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05270 f9c8fb4cff03fc430afbf120c516d019 551 SUPERFAMILY SSF52777 196 439 5.34E-34 T 09-03-2017 UA74_RS05270 f9c8fb4cff03fc430afbf120c516d019 551 Gene3D G3DSA:1.10.1200.10 476 549 1.5E-16 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS05270 f9c8fb4cff03fc430afbf120c516d019 551 SUPERFAMILY SSF52777 13 189 1.19E-43 T 09-03-2017 UA74_RS05270 f9c8fb4cff03fc430afbf120c516d019 551 SUPERFAMILY SSF47336 479 547 2.75E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS00815 7fd1c3fefcfdef6da9d310cb842a9b6e 194 SUPERFAMILY SSF159275 1 194 8.5E-41 T 09-03-2017 UA74_RS00815 7fd1c3fefcfdef6da9d310cb842a9b6e 194 Pfam PF06475 Putative glycolipid-binding 1 193 1.5E-43 T 09-03-2017 IPR009467 Putative glycolipid-binding protein UA74_RS14520 2366040bac25aaa44fe4337a9ae22a38 631 Pfam PF00245 Alkaline phosphatase 38 379 2.3E-54 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_RS14520 2366040bac25aaa44fe4337a9ae22a38 631 SMART SM00098 38 459 1.2E-13 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_RS14520 2366040bac25aaa44fe4337a9ae22a38 631 SUPERFAMILY SSF53649 23 458 3.32E-84 T 09-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 UA74_RS14520 2366040bac25aaa44fe4337a9ae22a38 631 PRINTS PR00113 Alkaline phosphatase signature 302 331 1.8E-17 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_RS14520 2366040bac25aaa44fe4337a9ae22a38 631 PRINTS PR00113 Alkaline phosphatase signature 37 57 1.8E-17 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_RS14520 2366040bac25aaa44fe4337a9ae22a38 631 PRINTS PR00113 Alkaline phosphatase signature 205 215 1.8E-17 T 09-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_RS14520 2366040bac25aaa44fe4337a9ae22a38 631 Gene3D G3DSA:3.40.720.10 25 458 5.4E-96 T 09-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 UA74_RS21175 43a4723a695737b890db27e68b835670 276 Pfam PF04962 KduI/IolB family 32 270 9.3E-30 T 09-03-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_RS21175 43a4723a695737b890db27e68b835670 276 Gene3D G3DSA:2.60.120.520 20 130 1.5E-38 T 09-03-2017 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_RS21175 43a4723a695737b890db27e68b835670 276 Gene3D G3DSA:2.60.120.500 131 276 1.8E-64 T 09-03-2017 IPR027447 5-keto-4-deoxyuronate isomerase, C-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_RS21175 43a4723a695737b890db27e68b835670 276 SUPERFAMILY SSF51182 1 260 2.54E-91 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS21175 43a4723a695737b890db27e68b835670 276 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 276 50.168 T 09-03-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_RS21175 43a4723a695737b890db27e68b835670 276 PIRSF PIRSF006625 1 276 3.8E-114 T 09-03-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_RS25770 ab8135194df00a913af30b80a5b8e39e 60 Pfam PF01783 Ribosomal L32p protein family 2 56 3.2E-26 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS25770 ab8135194df00a913af30b80a5b8e39e 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 57 18.467 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS25770 ab8135194df00a913af30b80a5b8e39e 60 SUPERFAMILY SSF57829 2 56 1.22E-19 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_RS25770 ab8135194df00a913af30b80a5b8e39e 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 2.6E-25 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS00565 98751b10106064f7ffe9a20c0b5c4820 178 Pfam PF00011 Hsp20/alpha crystallin family 52 150 1.8E-15 T 09-03-2017 IPR002068 Alpha crystallin/Hsp20 domain UA74_RS00565 98751b10106064f7ffe9a20c0b5c4820 178 Gene3D G3DSA:2.60.40.790 4 150 2.3E-27 T 09-03-2017 IPR008978 HSP20-like chaperone UA74_RS00565 98751b10106064f7ffe9a20c0b5c4820 178 SUPERFAMILY SSF49764 30 149 5.58E-27 T 09-03-2017 IPR008978 HSP20-like chaperone UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 SMART SM00347 27 126 2.0E-15 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 SUPERFAMILY SSF46785 12 138 1.92E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 Gene3D G3DSA:1.10.10.10 11 139 1.1E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 3.0E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 3.0E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 3.0E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 3.0E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS15055 78f20a25920d37d4dd0f5e5fa24954ae 152 Pfam PF13463 Winged helix DNA-binding domain 34 99 3.2E-12 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS13865 5d3e4285737408e068fc96eeb9ffc112 208 Gene3D G3DSA:3.90.1140.10 24 202 2.1E-18 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase UA74_RS13865 5d3e4285737408e068fc96eeb9ffc112 208 Pfam PF13563 2'-5' RNA ligase superfamily 50 184 3.1E-15 T 09-03-2017 UA74_RS13865 5d3e4285737408e068fc96eeb9ffc112 208 SUPERFAMILY SSF55144 26 200 1.12E-17 T 09-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase UA74_RS21385 8c5b850a42a071c697cedfa2493ca869 192 Pfam PF04892 VanZ like family 81 149 3.5E-7 T 09-03-2017 IPR006976 VanZ-like UA74_RS05210 f57a10b1c9a7351817a23fad2c27e493 472 SUPERFAMILY SSF52777 10 184 8.15E-37 T 09-03-2017 UA74_RS05210 f57a10b1c9a7351817a23fad2c27e493 472 SUPERFAMILY SSF52777 200 442 6.67E-29 T 09-03-2017 UA74_RS05210 f57a10b1c9a7351817a23fad2c27e493 472 Pfam PF00668 Condensation domain 4 310 8.6E-42 T 09-03-2017 IPR001242 Condensation domain UA74_RS27745 385d375dcb2d53edda2b2e6cc4b6d5ce 405 SMART SM01329 9 396 6.7E-137 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS27745 385d375dcb2d53edda2b2e6cc4b6d5ce 405 SUPERFAMILY SSF53659 2 404 1.56E-150 T 09-03-2017 UA74_RS27745 385d375dcb2d53edda2b2e6cc4b6d5ce 405 Gene3D G3DSA:3.40.718.10 3 404 4.9E-172 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS27745 385d375dcb2d53edda2b2e6cc4b6d5ce 405 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 404 1.9E-210 T 09-03-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 UA74_RS27745 385d375dcb2d53edda2b2e6cc4b6d5ce 405 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 271 290 - T 09-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UA74_RS27745 385d375dcb2d53edda2b2e6cc4b6d5ce 405 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 384 2.3E-70 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS27745 385d375dcb2d53edda2b2e6cc4b6d5ce 405 PIRSF PIRSF000108 1 405 2.1E-221 T 09-03-2017 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 UA74_RS14900 10ca43aad2dc267695e3b74f2532f9d5 328 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 306 5.4E-29 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS14900 10ca43aad2dc267695e3b74f2532f9d5 328 Gene3D G3DSA:3.40.50.1100 80 308 1.0E-29 T 09-03-2017 UA74_RS14900 10ca43aad2dc267695e3b74f2532f9d5 328 PIRSF PIRSF006278 1 316 1.4E-43 T 09-03-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase UA74_RS14900 10ca43aad2dc267695e3b74f2532f9d5 328 SUPERFAMILY SSF53686 4 306 3.17E-44 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS07860 0856ccaf6c1dcfa7739defcfe64a1aaf 430 SUPERFAMILY SSF53335 246 405 4.96E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07860 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Gene3D G3DSA:3.40.50.150 250 399 1.6E-14 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07860 0856ccaf6c1dcfa7739defcfe64a1aaf 430 SUPERFAMILY SSF102588 28 222 1.12E-43 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS07860 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Pfam PF02585 GlcNAc-PI de-N-acetylase 31 156 8.4E-26 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_RS07860 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Pfam PF05401 Nodulation protein S (NodS) 258 383 2.4E-14 T 09-03-2017 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 UA74_RS07860 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Gene3D G3DSA:3.40.50.10320 29 220 9.5E-42 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 Pfam PF00361 Proton-conducting membrane transporter 145 431 1.2E-85 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 2.3E-57 T 09-03-2017 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 233 254 2.3E-57 T 09-03-2017 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 430 449 2.3E-57 T 09-03-2017 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 323 335 2.3E-57 T 09-03-2017 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 168 189 2.3E-57 T 09-03-2017 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 255 281 2.3E-57 T 09-03-2017 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 429 451 1.9E-13 T 09-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 1.9E-13 T 09-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 273 295 1.9E-13 T 09-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 1.9E-13 T 09-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 638 4.3E-220 T 09-03-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02595 87a1b2e2e3285174626515721b86f3e2 644 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 132 2.7E-23 T 09-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS29905 bda12f00a88577f54ecf3d902c3ae54a 338 Gene3D G3DSA:3.40.50.1980 186 331 5.6E-14 T 09-03-2017 UA74_RS29905 bda12f00a88577f54ecf3d902c3ae54a 338 Pfam PF01497 Periplasmic binding protein 85 310 1.6E-32 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS29905 bda12f00a88577f54ecf3d902c3ae54a 338 SUPERFAMILY SSF53807 83 334 1.33E-41 T 09-03-2017 UA74_RS29905 bda12f00a88577f54ecf3d902c3ae54a 338 Gene3D G3DSA:3.40.50.1980 78 185 1.1E-18 T 09-03-2017 UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 Gene3D G3DSA:3.40.50.300 154 283 4.9E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 Gene3D G3DSA:3.40.50.300 331 577 1.4E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 Gene3D G3DSA:3.40.50.300 3 119 4.9E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 SUPERFAMILY SSF52540 333 575 1.63E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 SUPERFAMILY SSF52540 153 287 1.3E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 SUPERFAMILY SSF52540 3 101 1.3E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 Pfam PF00005 ABC transporter 354 504 4.3E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 Pfam PF00005 ABC transporter 24 211 5.7E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 555 581 4.0E-4 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 263 295 9.2E-4 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 SMART SM00382 32 244 2.5E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14060 374305eb7a9fc4c2a489529dbbb5fdee 582 SMART SM00382 362 553 8.0E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12680 a731fa88017b458afe3c27829540c654 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 239 1.1E-56 T 09-03-2017 UA74_RS12680 a731fa88017b458afe3c27829540c654 241 Gene3D G3DSA:3.40.50.720 1 240 5.6E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.1E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.1E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.1E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.0E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.0E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.0E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 2.0E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 2.0E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS12680 a731fa88017b458afe3c27829540c654 241 SUPERFAMILY SSF51735 1 240 2.34E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14785 c85fa52bff4f1a9ced39347f544db513 139 Gene3D G3DSA:1.10.10.10 75 112 2.0E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 SMART SM00448 2 115 1.1E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 SUPERFAMILY SSF52172 2 129 1.15E-31 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 Gene3D G3DSA:1.10.10.10 153 207 1.4E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 206 1.8E-13 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 SMART SM00421 151 208 3.9E-14 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 Gene3D G3DSA:3.40.50.2300 2 152 1.2E-34 T 09-03-2017 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.1E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.1E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.1E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 Pfam PF00072 Response regulator receiver domain 4 115 1.5E-23 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS20005 c2de927d2c6cc8fd90934dffc6535b5e 214 SUPERFAMILY SSF46894 142 210 9.52E-17 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS26145 1412abf636ac0b7f8eca57ef78168eed 614 SUPERFAMILY SSF52016 423 612 3.3E-59 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS26145 1412abf636ac0b7f8eca57ef78168eed 614 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 1.8E-232 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS26145 1412abf636ac0b7f8eca57ef78168eed 614 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS26145 1412abf636ac0b7f8eca57ef78168eed 614 SUPERFAMILY SSF143975 4 422 4.05E-131 T 09-03-2017 UA74_RS26145 1412abf636ac0b7f8eca57ef78168eed 614 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS26145 1412abf636ac0b7f8eca57ef78168eed 614 Pfam PF00920 Dehydratase family 34 608 6.5E-210 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS26145 1412abf636ac0b7f8eca57ef78168eed 614 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 44.388 T 09-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS03880 a476f41b9c42259ef1b1a84bd83c99c0 135 Gene3D G3DSA:2.70.70.10 3 128 2.8E-45 T 09-03-2017 UA74_RS03880 a476f41b9c42259ef1b1a84bd83c99c0 135 SUPERFAMILY SSF51261 6 127 4.08E-46 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS03880 a476f41b9c42259ef1b1a84bd83c99c0 135 Pfam PF01551 Peptidase family M23 29 123 2.0E-31 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS15220 a476f41b9c42259ef1b1a84bd83c99c0 135 Gene3D G3DSA:2.70.70.10 3 128 2.8E-45 T 09-03-2017 UA74_RS15220 a476f41b9c42259ef1b1a84bd83c99c0 135 SUPERFAMILY SSF51261 6 127 4.08E-46 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS15220 a476f41b9c42259ef1b1a84bd83c99c0 135 Pfam PF01551 Peptidase family M23 29 123 2.0E-31 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS09560 a476f41b9c42259ef1b1a84bd83c99c0 135 Gene3D G3DSA:2.70.70.10 3 128 2.8E-45 T 09-03-2017 UA74_RS09560 a476f41b9c42259ef1b1a84bd83c99c0 135 SUPERFAMILY SSF51261 6 127 4.08E-46 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS09560 a476f41b9c42259ef1b1a84bd83c99c0 135 Pfam PF01551 Peptidase family M23 29 123 2.0E-31 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 SUPERFAMILY SSF103473 473 496 1.29E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 SUPERFAMILY SSF103473 249 419 1.29E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 SUPERFAMILY SSF103473 7 199 1.29E-54 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 Gene3D G3DSA:1.20.1250.20 474 497 7.4E-15 T 09-03-2017 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 Gene3D G3DSA:1.20.1250.20 20 195 1.5E-25 T 09-03-2017 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 Gene3D G3DSA:1.20.1250.20 259 420 7.4E-15 T 09-03-2017 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 1.3E-6 T 09-03-2017 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 100 1.3E-6 T 09-03-2017 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 356 376 1.3E-6 T 09-03-2017 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 1.3E-6 T 09-03-2017 UA74_RS14295 8157d694a315c0e47051f98e4a46738e 518 Pfam PF07690 Major Facilitator Superfamily 23 409 4.8E-39 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 140 154 3.5E-14 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 225 237 3.5E-14 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 82 97 3.5E-14 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 226 237 - T 09-03-2017 IPR033116 Serine proteases, trypsin family, serine active site UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 92 97 - T 09-03-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 Gene3D G3DSA:2.40.10.10 91 287 3.6E-34 T 09-03-2017 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 SMART SM00020 55 282 1.5E-32 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 Gene3D G3DSA:2.40.10.10 56 90 1.2E-12 T 09-03-2017 UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 SUPERFAMILY SSF50494 46 286 1.27E-47 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS04135 f6bc20298d271d0bbc4a2ad1e1f54b75 288 Pfam PF00089 Trypsin 56 257 8.2E-34 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.7E-57 T 09-03-2017 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 Gene3D G3DSA:3.40.50.300 5 213 3.5E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 SUPERFAMILY SSF50465 305 397 6.04E-35 T 09-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 Gene3D G3DSA:2.40.30.10 214 301 2.6E-35 T 09-03-2017 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 Pfam PF03144 Elongation factor Tu domain 2 227 297 1.6E-17 T 09-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 Pfam PF03143 Elongation factor Tu C-terminal domain 303 395 1.0E-31 T 09-03-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 2.3E-217 T 09-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 SUPERFAMILY SSF50447 207 304 4.78E-30 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 58.189 T 09-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 9.9E-13 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 Gene3D G3DSA:2.40.30.10 303 395 4.1E-45 T 09-03-2017 UA74_RS02920 e77a62862c007231daf98dc062cea8bf 397 SUPERFAMILY SSF52540 6 221 2.78E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17930 4e23831a8f952f354a3315cb1b934e77 250 Gene3D G3DSA:1.10.357.10 23 245 6.8E-56 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS17930 4e23831a8f952f354a3315cb1b934e77 250 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 97 238 1.1E-16 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS17930 4e23831a8f952f354a3315cb1b934e77 250 SUPERFAMILY SSF48498 100 241 8.56E-19 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS17930 4e23831a8f952f354a3315cb1b934e77 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 3.3E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS17930 4e23831a8f952f354a3315cb1b934e77 250 SUPERFAMILY SSF46689 25 88 1.3E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS09390 5a429197defd0a150f7380c0ddc57fd4 284 SMART SM00530 17 74 3.9E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS09390 5a429197defd0a150f7380c0ddc57fd4 284 SUPERFAMILY SSF47413 13 80 2.96E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09390 5a429197defd0a150f7380c0ddc57fd4 284 Gene3D G3DSA:1.10.260.40 7 74 9.3E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09390 5a429197defd0a150f7380c0ddc57fd4 284 Pfam PF13560 Helix-turn-helix domain 14 71 1.9E-6 T 09-03-2017 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 SUPERFAMILY SSF51905 9 175 4.39E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 SUPERFAMILY SSF51905 278 380 4.39E-51 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.3E-19 T 09-03-2017 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.3E-19 T 09-03-2017 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 1.3E-19 T 09-03-2017 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 1.3E-19 T 09-03-2017 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 Gene3D G3DSA:3.50.50.60 279 352 2.7E-34 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 Gene3D G3DSA:3.50.50.60 8 180 2.7E-34 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03600 ca1636203ae83af4cbef52d4a800b4de 408 Pfam PF01494 FAD binding domain 7 350 1.6E-27 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS21945 a4693f78cea3a38e680667c159cf5f7e 543 SUPERFAMILY SSF56300 295 363 7.05E-11 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS21945 a4693f78cea3a38e680667c159cf5f7e 543 SUPERFAMILY SSF56300 410 475 7.05E-11 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS21945 a4693f78cea3a38e680667c159cf5f7e 543 SUPERFAMILY SSF56300 95 249 7.05E-11 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS21945 a4693f78cea3a38e680667c159cf5f7e 543 Pfam PF09423 PhoD-like phosphatase 122 456 1.2E-12 T 09-03-2017 IPR018946 Alkaline phosphatase D-related UA74_RS21945 a4693f78cea3a38e680667c159cf5f7e 543 Gene3D G3DSA:3.60.21.10 117 246 3.5E-9 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS21945 a4693f78cea3a38e680667c159cf5f7e 543 Gene3D G3DSA:3.60.21.10 296 357 3.5E-9 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS22320 0b2bd6ddf7a2a046c8f9df35f567666b 364 Pfam PF01032 FecCD transport family 39 359 1.9E-90 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS22320 0b2bd6ddf7a2a046c8f9df35f567666b 364 SUPERFAMILY SSF81345 22 359 2.75E-77 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS22320 0b2bd6ddf7a2a046c8f9df35f567666b 364 Gene3D G3DSA:1.10.3470.10 27 361 1.6E-102 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 SUPERFAMILY SSF53850 92 293 7.6E-24 T 09-03-2017 UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 Pfam PF03466 LysR substrate binding domain 91 290 4.9E-27 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 SUPERFAMILY SSF46785 4 86 2.66E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 7.4E-25 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 Gene3D G3DSA:1.10.10.10 4 87 3.9E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.0E-10 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.0E-10 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.0E-10 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 Gene3D G3DSA:3.40.190.10 94 176 3.0E-14 T 09-03-2017 UA74_RS07660 e8d15abff630767cdcbbbbf429643977 308 Gene3D G3DSA:3.40.190.10 177 265 1.3E-10 T 09-03-2017 UA74_RS23695 4f1ddfdc2c94f0e94ec633e8629ac70d 159 PIRSF PIRSF000239 1 156 3.5E-18 T 09-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS23695 4f1ddfdc2c94f0e94ec633e8629ac70d 159 SUPERFAMILY SSF52833 3 149 1.59E-41 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS23695 4f1ddfdc2c94f0e94ec633e8629ac70d 159 Gene3D G3DSA:3.40.30.10 2 149 2.4E-37 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS23695 4f1ddfdc2c94f0e94ec633e8629ac70d 159 Pfam PF00578 AhpC/TSA family 4 125 5.6E-29 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS02385 7e26fa06bd4f3e82c110ca0b4db45c2c 324 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 87 321 3.0E-72 T 09-03-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 UA74_RS02385 7e26fa06bd4f3e82c110ca0b4db45c2c 324 Pfam PF01578 Cytochrome C assembly protein 110 318 5.7E-44 T 09-03-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 UA74_RS17455 c1a826af364bed8c724f1705d53510b1 490 Pfam PF07690 Major Facilitator Superfamily 26 420 4.4E-44 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS17455 c1a826af364bed8c724f1705d53510b1 490 Gene3D G3DSA:1.20.1250.20 271 472 3.3E-21 T 09-03-2017 UA74_RS17455 c1a826af364bed8c724f1705d53510b1 490 Gene3D G3DSA:1.20.1250.20 24 199 2.9E-28 T 09-03-2017 UA74_RS17455 c1a826af364bed8c724f1705d53510b1 490 SUPERFAMILY SSF103473 20 210 5.49E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS17455 c1a826af364bed8c724f1705d53510b1 490 SUPERFAMILY SSF103473 256 473 5.49E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS12155 1296c7668e81970fab20c0d31e3d2686 281 Gene3D G3DSA:1.10.260.40 13 68 5.3E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS12155 1296c7668e81970fab20c0d31e3d2686 281 SMART SM00530 17 72 0.0032 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS12155 1296c7668e81970fab20c0d31e3d2686 281 SUPERFAMILY SSF47413 8 72 4.1E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS12155 1296c7668e81970fab20c0d31e3d2686 281 Pfam PF13560 Helix-turn-helix domain 14 75 1.4E-8 T 09-03-2017 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 SUPERFAMILY SSF143800 2 66 8.63E-25 T 09-03-2017 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 Pfam PF01197 Ribosomal protein L31 2 66 4.2E-30 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 PRINTS PR01249 Ribosomal protein L31 signature 32 47 2.9E-21 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 PRINTS PR01249 Ribosomal protein L31 signature 47 65 2.9E-21 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.9E-21 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 27.99 T 09-03-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS07100 2dc0127ea8def50550f1cbf468df9003 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 1.6E-31 T 09-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 Gene3D G3DSA:3.40.50.300 10 216 1.2E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 SUPERFAMILY SSF50447 223 313 7.49E-19 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 Gene3D G3DSA:2.40.30.10 224 349 2.1E-22 T 09-03-2017 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 63 78 - T 09-03-2017 IPR031157 Tr-type G domain, conserved site UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 SUPERFAMILY SSF52540 9 217 3.64E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 SUPERFAMILY SSF50465 319 420 1.01E-22 T 09-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 PRINTS PR00315 GTP-binding elongation factor signature 11 24 7.1E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 PRINTS PR00315 GTP-binding elongation factor signature 70 78 7.1E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 PRINTS PR00315 GTP-binding elongation factor signature 106 117 7.1E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 PRINTS PR00315 GTP-binding elongation factor signature 143 152 7.1E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 PRINTS PR00315 GTP-binding elongation factor signature 90 100 7.1E-13 T 09-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 10 420 8.8E-164 T 09-03-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 UA74_RS24650 8bbfaec7a6f86cf744a24608150d147f 423 Pfam PF00009 Elongation factor Tu GTP binding domain 11 195 2.3E-37 T 09-03-2017 UA74_RS23775 198520f56347219b147172db9a5b2f71 429 SUPERFAMILY SSF55681 7 347 1.9E-68 T 09-03-2017 UA74_RS23775 198520f56347219b147172db9a5b2f71 429 Pfam PF13393 Histidyl-tRNA synthetase 10 341 3.4E-47 T 09-03-2017 UA74_RS23775 198520f56347219b147172db9a5b2f71 429 PIRSF PIRSF001549 2 427 1.8E-95 T 09-03-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 UA74_RS23775 198520f56347219b147172db9a5b2f71 429 Gene3D G3DSA:3.30.930.10 259 345 1.8E-77 T 09-03-2017 UA74_RS23775 198520f56347219b147172db9a5b2f71 429 Gene3D G3DSA:3.30.930.10 6 206 1.8E-77 T 09-03-2017 UA74_RS23775 198520f56347219b147172db9a5b2f71 429 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 411 6.7E-89 T 09-03-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 UA74_RS00935 9bb83ef24431b913f742324405739dbc 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 240 3.3E-36 T 09-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 UA74_RS00935 9bb83ef24431b913f742324405739dbc 255 SUPERFAMILY SSF51621 6 252 7.07E-64 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS00935 9bb83ef24431b913f742324405739dbc 255 Gene3D G3DSA:3.20.20.60 7 252 5.6E-65 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS27895 cad62c5d7dd2a5a56037c4c5210aa575 377 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 19 212 1.1E-30 T 09-03-2017 UA74_RS27895 cad62c5d7dd2a5a56037c4c5210aa575 377 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 168 183 - T 09-03-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_RS27895 cad62c5d7dd2a5a56037c4c5210aa575 377 Gene3D G3DSA:3.40.50.150 21 251 1.4E-51 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS27895 cad62c5d7dd2a5a56037c4c5210aa575 377 SUPERFAMILY SSF53335 17 212 1.49E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24565 7c6e054e43b213a87a15ba29afcab8c3 122 Gene3D G3DSA:1.10.10.10 3 72 1.9E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24565 7c6e054e43b213a87a15ba29afcab8c3 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.5E-6 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS24565 7c6e054e43b213a87a15ba29afcab8c3 122 SMART SM00345 12 71 1.2E-4 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS24565 7c6e054e43b213a87a15ba29afcab8c3 122 SUPERFAMILY SSF46785 4 84 1.94E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12990 fa4de972cdb3a8c374ac226c61b32ffb 262 Pfam PF00227 Proteasome subunit 25 187 7.3E-28 T 09-03-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 UA74_RS12990 fa4de972cdb3a8c374ac226c61b32ffb 262 SUPERFAMILY SSF56235 10 236 6.87E-38 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS12990 fa4de972cdb3a8c374ac226c61b32ffb 262 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 240 47.463 T 09-03-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UA74_RS12990 fa4de972cdb3a8c374ac226c61b32ffb 262 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 236 2.5E-102 T 09-03-2017 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UA74_RS12990 fa4de972cdb3a8c374ac226c61b32ffb 262 Gene3D G3DSA:3.60.20.10 3 242 1.8E-76 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS25905 3821e3b514545f12eb8be8e56ff03d4b 225 Gene3D G3DSA:3.40.470.10 6 224 2.1E-79 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS25905 3821e3b514545f12eb8be8e56ff03d4b 225 SMART SM00986 53 212 5.2E-29 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS25905 3821e3b514545f12eb8be8e56ff03d4b 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 09-03-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS25905 3821e3b514545f12eb8be8e56ff03d4b 225 Pfam PF03167 Uracil DNA glycosylase superfamily 56 211 2.1E-16 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS25905 3821e3b514545f12eb8be8e56ff03d4b 225 SMART SM00987 53 212 5.2E-29 T 09-03-2017 UA74_RS25905 3821e3b514545f12eb8be8e56ff03d4b 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 32.951 T 09-03-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS25905 3821e3b514545f12eb8be8e56ff03d4b 225 SUPERFAMILY SSF52141 8 223 3.92E-70 T 09-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 Gene3D G3DSA:1.10.10.10 7 68 6.9E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 Pfam PF07729 FCD domain 96 211 1.3E-22 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 Gene3D G3DSA:1.20.120.530 92 224 7.6E-24 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 SUPERFAMILY SSF48008 94 221 6.28E-23 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 SUPERFAMILY SSF46785 7 71 8.33E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 7.9E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 SMART SM00345 8 67 2.1E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 2.3E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 2.3E-7 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS10185 32d3492c70a2552fb05dbd3e0e087ca4 229 SMART SM00895 96 213 1.5E-16 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS09920 af16c20c54b70fa21fb0d0baee1a27d6 347 Pfam PF02445 Quinolinate synthetase A protein 35 339 1.2E-110 T 09-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UA74_RS09920 af16c20c54b70fa21fb0d0baee1a27d6 347 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 32 340 3.6E-88 T 09-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UA74_RS09920 af16c20c54b70fa21fb0d0baee1a27d6 347 SUPERFAMILY SSF142754 32 340 2.35E-101 T 09-03-2017 UA74_RS03445 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Gene3D G3DSA:1.10.530.10 276 369 4.9E-32 T 09-03-2017 UA74_RS03445 5f0b3045da0ae36b7fadf20ac0b0ced4 371 SMART SM01208 200 278 1.3E-27 T 09-03-2017 IPR011098 G5 domain UA74_RS03445 5f0b3045da0ae36b7fadf20ac0b0ced4 371 SUPERFAMILY SSF53955 286 369 1.87E-24 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS03445 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF06737 Transglycosylase-like domain 287 363 3.2E-24 T 09-03-2017 IPR010618 Transglycosylase-like UA74_RS03445 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF03990 Domain of unknown function (DUF348) 148 187 1.1E-8 T 09-03-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 UA74_RS03445 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF03990 Domain of unknown function (DUF348) 32 72 1.6E-12 T 09-03-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 UA74_RS03445 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF07501 G5 domain 204 277 3.3E-24 T 09-03-2017 IPR011098 G5 domain UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 63 78 4.1E-24 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 43 61 4.1E-24 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 121 134 4.1E-24 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 290 312 4.1E-24 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 107 120 4.1E-24 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 4.9E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 4.9E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 4.9E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 SUPERFAMILY SSF53474 14 314 7.19E-67 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 Gene3D G3DSA:3.40.50.1820 5 314 2.0E-73 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01255 f12b56cdbc7f2d1c1df8e40b798a2f95 319 Pfam PF00561 alpha/beta hydrolase fold 37 299 1.0E-21 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS29525 7707db7cf23a865d00c51cfdf374a13f 392 SUPERFAMILY SSF53383 14 389 2.24E-96 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS29525 7707db7cf23a865d00c51cfdf374a13f 392 Pfam PF00155 Aminotransferase class I and II 37 384 1.8E-57 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS29525 7707db7cf23a865d00c51cfdf374a13f 392 Gene3D G3DSA:3.40.640.10 51 256 8.4E-59 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS29525 7707db7cf23a865d00c51cfdf374a13f 392 Gene3D G3DSA:3.90.1150.10 257 388 1.5E-31 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS29525 7707db7cf23a865d00c51cfdf374a13f 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_RS03305 f4a81e201dc4279f161e24fa15bf3f3d 283 SUPERFAMILY SSF51679 1 282 6.92E-43 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS03305 f4a81e201dc4279f161e24fa15bf3f3d 283 Pfam PF00296 Luciferase-like monooxygenase 19 230 8.8E-27 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS03305 f4a81e201dc4279f161e24fa15bf3f3d 283 Gene3D G3DSA:3.20.20.30 1 282 1.2E-43 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS07920 4551636991d1ba25fcc6693fa930a5b2 559 Pfam PF00999 Sodium/hydrogen exchanger family 8 403 2.4E-51 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UA74_RS07920 4551636991d1ba25fcc6693fa930a5b2 559 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 10 465 1.1E-100 T 09-03-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 SUPERFAMILY SSF51971 346 375 7.65E-46 T 09-03-2017 UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 SUPERFAMILY SSF51971 6 273 7.65E-46 T 09-03-2017 UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 79 2.1E-17 T 09-03-2017 UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 Gene3D G3DSA:3.40.50.720 6 85 7.3E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 Gene3D G3DSA:3.40.50.720 333 380 7.3E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 Gene3D G3DSA:3.40.50.720 189 263 7.3E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 6 379 3.4E-105 T 09-03-2017 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 Pfam PF03275 UDP-galactopyranose mutase 154 361 2.4E-81 T 09-03-2017 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 UA74_RS00670 45da195e8325a6270d0dbbf59e36d71d 395 SUPERFAMILY SSF54373 254 325 2.35E-22 T 09-03-2017 UA74_RS13870 43e789c53b98e8c81efb155f00389c12 163 Gene3D G3DSA:3.30.530.20 1 153 2.1E-12 T 09-03-2017 IPR023393 START-like domain UA74_RS13870 43e789c53b98e8c81efb155f00389c12 163 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 150 6.4E-8 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS13870 43e789c53b98e8c81efb155f00389c12 163 SUPERFAMILY SSF55961 1 156 2.42E-21 T 09-03-2017 UA74_RS21500 2bfc3afca32d497a9cb6318fa37120e4 198 SUPERFAMILY SSF55729 23 174 7.52E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS21500 2bfc3afca32d497a9cb6318fa37120e4 198 Pfam PF13302 Acetyltransferase (GNAT) domain 27 167 1.3E-20 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS21500 2bfc3afca32d497a9cb6318fa37120e4 198 Gene3D G3DSA:3.40.630.30 23 174 1.7E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS21965 4a99e08cd0acebd732dcbca8a6c7dd00 174 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 5 159 2.3E-30 T 09-03-2017 IPR017516 AbrB duplication UA74_RS21965 4a99e08cd0acebd732dcbca8a6c7dd00 174 Pfam PF05145 Putative ammonia monooxygenase 5 159 2.2E-25 T 09-03-2017 IPR007820 AbrB family GO:0010468|GO:0016021 UA74_RS06835 87e23c87069bc0fa340389c24351c9dc 425 Gene3D G3DSA:3.40.190.10 34 164 3.6E-13 T 09-03-2017 UA74_RS06835 87e23c87069bc0fa340389c24351c9dc 425 Gene3D G3DSA:3.40.190.10 165 354 4.5E-23 T 09-03-2017 UA74_RS06835 87e23c87069bc0fa340389c24351c9dc 425 SUPERFAMILY SSF53850 33 422 1.76E-48 T 09-03-2017 UA74_RS06835 87e23c87069bc0fa340389c24351c9dc 425 Pfam PF13416 Bacterial extracellular solute-binding protein 52 355 2.3E-26 T 09-03-2017 UA74_RS04850 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Gene3D G3DSA:3.30.830.10 239 419 2.5E-12 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 UA74_RS04850 ae7f03f129c2eb95ebbd6d35f2bfe116 430 SUPERFAMILY SSF63411 231 421 3.67E-18 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_RS04850 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Pfam PF00675 Insulinase (Peptidase family M16) 17 131 3.9E-18 T 09-03-2017 IPR011765 Peptidase M16, N-terminal UA74_RS04850 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Gene3D G3DSA:3.30.830.10 4 223 6.5E-45 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 UA74_RS04850 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Pfam PF05193 Peptidase M16 inactive domain 173 353 6.9E-18 T 09-03-2017 IPR007863 Peptidase M16, C-terminal UA74_RS04850 ae7f03f129c2eb95ebbd6d35f2bfe116 430 SUPERFAMILY SSF63411 5 220 1.25E-48 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_RS20085 489acd95797fe7260264d617be762f98 267 SUPERFAMILY SSF51351 10 254 1.01E-53 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS20085 489acd95797fe7260264d617be762f98 267 Pfam PF00121 Triosephosphate isomerase 12 247 8.0E-46 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS20085 489acd95797fe7260264d617be762f98 267 Gene3D G3DSA:3.20.20.70 11 257 1.7E-64 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 SMART SM00344 10 116 7.8E-22 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 6.8E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 6.8E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 6.8E-7 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 Gene3D G3DSA:3.30.70.920 62 147 2.9E-19 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 Pfam PF13404 AsnC-type helix-turn-helix domain 10 50 2.2E-6 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 SUPERFAMILY SSF46785 9 70 4.81E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 Pfam PF01037 Lrp/AsnC ligand binding domain 84 146 4.5E-15 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 Gene3D G3DSA:1.10.10.10 9 59 9.6E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04010 fa2f9f2adc8bb27299c72248da6fd760 166 SUPERFAMILY SSF54909 70 154 5.09E-18 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS28090 d31b9681eff58d8d8d25c9df7e9691f0 100 Pfam PF02467 Transcription factor WhiB 17 85 2.1E-24 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS28090 d31b9681eff58d8d8d25c9df7e9691f0 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.752 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS07715 e0f65315b375148559d1cd92721f48a4 404 Pfam PF13546 DDE superfamily endonuclease 26 250 1.2E-56 T 09-03-2017 UA74_RS07715 e0f65315b375148559d1cd92721f48a4 404 SUPERFAMILY SSF53098 16 392 1.06E-6 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS01425 7d1a0cd636d607a21b580845c1353d2b 410 Pfam PF13177 DNA polymerase III, delta subunit 48 193 2.1E-33 T 09-03-2017 UA74_RS01425 7d1a0cd636d607a21b580845c1353d2b 410 Gene3D G3DSA:1.20.272.10 326 403 2.1E-4 T 09-03-2017 UA74_RS01425 7d1a0cd636d607a21b580845c1353d2b 410 Gene3D G3DSA:3.40.50.300 16 193 1.6E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01425 7d1a0cd636d607a21b580845c1353d2b 410 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 48 228 1.9E-55 T 09-03-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS01425 7d1a0cd636d607a21b580845c1353d2b 410 SUPERFAMILY SSF52540 16 232 1.59E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24765 26b4090f11f22285084a1e4d76791b34 168 Gene3D G3DSA:3.90.960.10 8 162 2.8E-41 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS24765 26b4090f11f22285084a1e4d76791b34 168 Pfam PF04073 Aminoacyl-tRNA editing domain 33 151 6.2E-27 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS24765 26b4090f11f22285084a1e4d76791b34 168 SUPERFAMILY SSF55826 12 159 5.89E-33 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 PRINTS PR00050 Cold shock protein signature 39 57 1.1E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 PRINTS PR00050 Cold shock protein signature 24 33 1.1E-17 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 09-03-2017 IPR019844 Cold-shock conserved site UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 PIRSF PIRSF002599 1 66 5.6E-25 T 09-03-2017 IPR012156 Cold shock, CspA GO:0003676 UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 SMART SM00357 3 66 2.9E-29 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 Gene3D G3DSA:2.40.50.140 1 64 1.6E-31 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 SUPERFAMILY SSF50249 1 65 2.06E-24 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS14075 7af4bca60a26be37ac8bd3e0d17cbd80 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.1E-29 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 Gene3D G3DSA:3.40.50.1820 14 243 2.8E-58 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 Gene3D G3DSA:3.40.50.1820 310 420 2.8E-58 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 Pfam PF00561 alpha/beta hydrolase fold 49 231 1.9E-17 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 2.6E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 140 154 2.6E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 2.6E-9 T 09-03-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 SUPERFAMILY SSF53474 42 170 3.94E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS03395 61dab505ff67f3f759fd2817ba83bc85 427 SUPERFAMILY SSF53474 270 419 3.94E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14600 cc8aca53116517a4931339586f9bb6be 285 Gene3D G3DSA:3.40.190.10 68 151 1.2E-15 T 09-03-2017 UA74_RS14600 cc8aca53116517a4931339586f9bb6be 285 Gene3D G3DSA:3.40.190.10 152 229 6.5E-16 T 09-03-2017 UA74_RS14600 cc8aca53116517a4931339586f9bb6be 285 Gene3D G3DSA:1.10.10.10 2 60 5.1E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14600 cc8aca53116517a4931339586f9bb6be 285 SUPERFAMILY SSF46785 2 59 1.66E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14600 cc8aca53116517a4931339586f9bb6be 285 SUPERFAMILY SSF53850 66 277 2.01E-28 T 09-03-2017 UA74_RS14600 cc8aca53116517a4931339586f9bb6be 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 40 1.2E-13 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS14600 cc8aca53116517a4931339586f9bb6be 285 Pfam PF03466 LysR substrate binding domain 66 271 1.3E-26 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS01875 b733d96b31427ce0ff7a7680cf6546af 537 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 74 501 55.347 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_RS01875 b733d96b31427ce0ff7a7680cf6546af 537 Pfam PF01964 Radical SAM ThiC family 75 495 1.3E-198 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_RS01875 b733d96b31427ce0ff7a7680cf6546af 537 Pfam PF13667 ThiC-associated domain 3 64 3.2E-13 T 09-03-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_RS01875 b733d96b31427ce0ff7a7680cf6546af 537 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 75 498 1.4E-207 T 09-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_RS24955 8eb8433a07beb1505ac6050a15f5ab62 247 SMART SM00563 35 154 6.3E-36 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS24955 8eb8433a07beb1505ac6050a15f5ab62 247 Gene3D G3DSA:3.40.1130.10 2 207 8.7E-34 T 09-03-2017 UA74_RS24955 8eb8433a07beb1505ac6050a15f5ab62 247 SUPERFAMILY SSF69593 2 226 1.31E-54 T 09-03-2017 UA74_RS24955 8eb8433a07beb1505ac6050a15f5ab62 247 Pfam PF01553 Acyltransferase 21 151 5.8E-26 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS00525 bc663a42e10caccb23d905060ae5ec0e 401 Gene3D G3DSA:3.90.850.10 111 380 6.1E-98 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS00525 bc663a42e10caccb23d905060ae5ec0e 401 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 2 398 2.1E-115 T 09-03-2017 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_RS00525 bc663a42e10caccb23d905060ae5ec0e 401 SUPERFAMILY SSF63433 2 108 1.7E-15 T 09-03-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_RS00525 bc663a42e10caccb23d905060ae5ec0e 401 SUPERFAMILY SSF56529 111 398 2.09E-88 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS00525 bc663a42e10caccb23d905060ae5ec0e 401 Pfam PF09298 Fumarylacetoacetase N-terminal 18 108 1.1E-8 T 09-03-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_RS00525 bc663a42e10caccb23d905060ae5ec0e 401 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 114 392 1.4E-53 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS00525 bc663a42e10caccb23d905060ae5ec0e 401 Gene3D G3DSA:2.30.30.230 2 110 1.7E-16 T 09-03-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_RS08485 4c88383198b26e4ed42c54389a378280 582 SUPERFAMILY SSF52540 13 170 2.89E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08485 4c88383198b26e4ed42c54389a378280 582 Gene3D G3DSA:3.40.50.300 266 372 3.1E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08485 4c88383198b26e4ed42c54389a378280 582 Pfam PF04851 Type III restriction enzyme, res subunit 13 166 1.2E-13 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_RS08485 4c88383198b26e4ed42c54389a378280 582 SUPERFAMILY SSF52540 258 373 4.78E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08485 4c88383198b26e4ed42c54389a378280 582 SUPERFAMILY SSF52540 128 198 4.78E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08485 4c88383198b26e4ed42c54389a378280 582 Gene3D G3DSA:3.40.50.300 12 170 1.2E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08485 4c88383198b26e4ed42c54389a378280 582 SMART SM00487 10 193 4.8E-12 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:3.90.800.10 76 198 5.2E-33 T 09-03-2017 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 SUPERFAMILY SSF52374 11 323 4.56E-97 T 09-03-2017 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:1.10.10.350 403 493 1.4E-22 T 09-03-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 11 494 31.605 T 09-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 SUPERFAMILY SSF48163 324 494 1.44E-36 T 09-03-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 39 4.7E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 4.7E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 14 26 4.7E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 43 56 4.7E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 4.7E-22 T 09-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 11 492 4.4E-126 T 09-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:3.40.50.620 200 254 5.8E-43 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:3.40.50.620 11 75 5.8E-43 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:1.10.1160.10 257 339 7.0E-30 T 09-03-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 UA74_RS26070 34a81c21289c83cfc12859a8033a4b60 498 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 11 327 2.2E-78 T 09-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 UA74_RS00445 51d243976a7bba70f23aed598d5ebe42 275 SUPERFAMILY SSF51695 3 264 1.83E-60 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS00445 51d243976a7bba70f23aed598d5ebe42 275 Gene3D G3DSA:3.20.20.190 2 266 1.4E-65 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS00445 51d243976a7bba70f23aed598d5ebe42 275 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 258 9.2E-39 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 Gene3D G3DSA:1.20.1340.10 1 81 2.4E-28 T 09-03-2017 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 73 92 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 391 410 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 138 158 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 348 363 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 29 46 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 94 112 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 113 132 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 47 66 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 6 25 2.3E-54 T 09-03-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 SUPERFAMILY SSF53383 1 474 8.25E-133 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 Gene3D G3DSA:3.40.640.10 83 362 2.7E-96 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 35 409 6.4E-101 T 09-03-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 292 313 - T 09-03-2017 IPR021115 Pyridoxal-phosphate binding site GO:0016831 UA74_RS21365 b77f73cc27a417abd464f0f09d8647fd 476 Gene3D G3DSA:3.90.1150.10 363 473 1.4E-29 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS20405 644feea5ffa7a3c73aa3333f02695034 317 Gene3D G3DSA:3.40.50.1980 148 310 6.1E-30 T 09-03-2017 UA74_RS20405 644feea5ffa7a3c73aa3333f02695034 317 SUPERFAMILY SSF53807 29 306 1.02E-52 T 09-03-2017 UA74_RS20405 644feea5ffa7a3c73aa3333f02695034 317 Gene3D G3DSA:3.40.50.1980 27 147 3.0E-28 T 09-03-2017 UA74_RS20405 644feea5ffa7a3c73aa3333f02695034 317 Pfam PF01497 Periplasmic binding protein 47 278 1.4E-23 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS01590 f49244b5e345f910a53e887d447285ff 255 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 220 241 8.1E-7 T 09-03-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 Pfam PF04542 Sigma-70 region 2 7 73 3.1E-13 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 164 1.2E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 SUPERFAMILY SSF88659 112 166 3.18E-10 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 Pfam PF08281 Sigma-70, region 4 119 164 6.5E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 SUPERFAMILY SSF88946 4 93 3.22E-14 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 Gene3D G3DSA:1.10.1740.10 3 75 2.3E-14 T 09-03-2017 UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 SUPERFAMILY SSF54427 176 323 4.61E-15 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 Gene3D G3DSA:1.10.10.10 119 167 2.1E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24465 60adca3dee688be749f4bd165ef2a193 326 Gene3D G3DSA:3.10.450.50 176 323 1.6E-13 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS05180 8ca5a7980df51216b0c6ab7351de0bed 270 SUPERFAMILY SSF75217 109 265 8.5E-44 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS05180 8ca5a7980df51216b0c6ab7351de0bed 270 Gene3D G3DSA:3.30.1330.30 10 105 1.7E-24 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS05180 8ca5a7980df51216b0c6ab7351de0bed 270 SUPERFAMILY SSF55315 4 103 2.75E-22 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS05180 8ca5a7980df51216b0c6ab7351de0bed 270 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 33 103 1.6E-7 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS05180 8ca5a7980df51216b0c6ab7351de0bed 270 SMART SM00967 32 108 1.1E-8 T 09-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 UA74_RS05180 8ca5a7980df51216b0c6ab7351de0bed 270 Pfam PF00588 SpoU rRNA Methylase family 119 259 4.4E-37 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_RS05180 8ca5a7980df51216b0c6ab7351de0bed 270 Gene3D G3DSA:3.40.1280.10 118 264 6.2E-49 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 SUPERFAMILY SSF88946 74 171 1.7E-27 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 PRINTS PR00046 Major sigma-70 factor signature 126 139 2.7E-12 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 PRINTS PR00046 Major sigma-70 factor signature 274 286 2.7E-12 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 PRINTS PR00046 Major sigma-70 factor signature 291 306 2.7E-12 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 PRINTS PR00046 Major sigma-70 factor signature 306 317 2.7E-12 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 SUPERFAMILY SSF88659 238 323 1.2E-21 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 Gene3D G3DSA:1.10.10.10 171 216 4.2E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 126 139 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 Pfam PF04542 Sigma-70 region 2 99 171 6.0E-18 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 Gene3D G3DSA:1.10.601.10 88 165 2.7E-20 T 09-03-2017 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 SUPERFAMILY SSF88659 172 249 2.62E-13 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 Pfam PF04545 Sigma-70, region 4 270 319 1.6E-16 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 291 317 - T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 Gene3D G3DSA:1.10.10.10 259 323 6.3E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 99 321 1.9E-83 T 09-03-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 Pfam PF04539 Sigma-70 region 3 180 255 1.1E-6 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS09025 38b6dd384197608303d56c5f9bab6a94 325 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 96 321 4.3E-34 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS25595 b751ac2fa109da4ffc6f81aca1773215 82 Hamap MF_01217 Acyl carrier protein [acpP]. 8 82 16.822 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS25595 b751ac2fa109da4ffc6f81aca1773215 82 Gene3D G3DSA:1.10.1200.10 7 80 4.4E-24 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS25595 b751ac2fa109da4ffc6f81aca1773215 82 SUPERFAMILY SSF47336 7 81 8.77E-21 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS25595 b751ac2fa109da4ffc6f81aca1773215 82 Pfam PF00550 Phosphopantetheine attachment site 12 78 6.4E-16 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS25595 b751ac2fa109da4ffc6f81aca1773215 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 45 78 2.0E-9 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS25595 b751ac2fa109da4ffc6f81aca1773215 82 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 9 82 1.4E-20 T 09-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 Gene3D G3DSA:1.10.10.10 923 980 4.3E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 Gene3D G3DSA:3.40.50.300 181 235 1.5E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 Gene3D G3DSA:3.40.50.300 23 86 1.5E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 Pfam PF00196 Bacterial regulatory proteins, luxR family 926 979 2.3E-12 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 SUPERFAMILY SSF52540 28 74 4.09E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 SUPERFAMILY SSF52540 166 260 4.09E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 SMART SM00421 923 980 1.7E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 956 968 2.0E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 926 940 2.0E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 940 956 2.0E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 SUPERFAMILY SSF46894 922 980 1.5E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS13650 0524e41fff11cced7a33578052cdc00c 1038 Pfam PF13191 AAA ATPase domain 20 222 9.6E-12 T 09-03-2017 UA74_RS28850 8d6c8514035f7965bcf89ad7c61281e5 497 Gene3D G3DSA:3.40.50.720 338 484 7.4E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28850 8d6c8514035f7965bcf89ad7c61281e5 497 Gene3D G3DSA:3.40.50.720 141 244 7.4E-47 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28850 8d6c8514035f7965bcf89ad7c61281e5 497 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 342 443 8.7E-7 T 09-03-2017 UA74_RS28850 8d6c8514035f7965bcf89ad7c61281e5 497 Pfam PF00106 short chain dehydrogenase 160 247 8.3E-9 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS28850 8d6c8514035f7965bcf89ad7c61281e5 497 SUPERFAMILY SSF51735 154 252 1.81E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28850 8d6c8514035f7965bcf89ad7c61281e5 497 SUPERFAMILY SSF51735 343 455 1.81E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05010 0600df9cca125253c7a3c6ee30aa1ded 653 SUPERFAMILY SSF51004 65 197 6.8E-14 T 09-03-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain UA74_RS05010 0600df9cca125253c7a3c6ee30aa1ded 653 SUPERFAMILY SSF51004 234 308 6.8E-14 T 09-03-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain UA74_RS05010 0600df9cca125253c7a3c6ee30aa1ded 653 Gene3D G3DSA:2.130.10.10 53 195 8.9E-20 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS05010 0600df9cca125253c7a3c6ee30aa1ded 653 Gene3D G3DSA:2.130.10.10 232 338 8.9E-20 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS05010 0600df9cca125253c7a3c6ee30aa1ded 653 Gene3D G3DSA:2.130.10.10 408 503 8.9E-20 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS24675 0bda3751334250e7298216851a92b461 248 SUPERFAMILY SSF53800 12 243 5.01E-34 T 09-03-2017 UA74_RS24675 0bda3751334250e7298216851a92b461 248 Gene3D G3DSA:3.40.50.1400 132 244 1.3E-22 T 09-03-2017 UA74_RS24675 0bda3751334250e7298216851a92b461 248 Gene3D G3DSA:3.40.50.1400 11 126 5.8E-25 T 09-03-2017 UA74_RS24675 0bda3751334250e7298216851a92b461 248 Pfam PF01903 CbiX 17 115 1.1E-18 T 09-03-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 UA74_RS24675 0bda3751334250e7298216851a92b461 248 Pfam PF01903 CbiX 140 237 6.2E-14 T 09-03-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 UA74_RS28410 a01b47f70aa52e40d4d6c18b20f94504 405 Pfam PF01979 Amidohydrolase family 56 382 1.6E-14 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS28410 a01b47f70aa52e40d4d6c18b20f94504 405 SUPERFAMILY SSF51556 58 352 6.19E-46 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS28410 a01b47f70aa52e40d4d6c18b20f94504 405 Gene3D G3DSA:3.20.20.140 65 385 5.3E-34 T 09-03-2017 UA74_RS28410 a01b47f70aa52e40d4d6c18b20f94504 405 Gene3D G3DSA:2.30.40.10 3 64 1.1E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS28410 a01b47f70aa52e40d4d6c18b20f94504 405 SUPERFAMILY SSF51338 351 387 1.98E-22 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS28410 a01b47f70aa52e40d4d6c18b20f94504 405 SUPERFAMILY SSF51338 1 59 1.98E-22 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 SMART SM00997 245 407 4.2E-105 T 09-03-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 13 486 1.2E-142 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 SMART SM00996 13 486 0.0 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 9 479 47.729 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 SUPERFAMILY SSF51735 245 407 9.29E-75 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 Gene3D G3DSA:3.40.50.720 247 406 1.0E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 245 407 4.7E-80 T 09-03-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 267 283 - T 09-03-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 Gene3D G3DSA:3.40.50.1480 13 246 2.2E-140 T 09-03-2017 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 Gene3D G3DSA:3.40.50.1480 408 487 2.2E-140 T 09-03-2017 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 14 479 3.6E-189 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 PIRSF PIRSF001109 1 487 2.8E-188 T 09-03-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 SUPERFAMILY SSF52283 408 487 6.23E-109 T 09-03-2017 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 SUPERFAMILY SSF52283 12 159 6.23E-109 T 09-03-2017 UA74_RS26760 889f7d7eab8608df0d4a03df7c4b4c16 487 SUPERFAMILY SSF52283 197 244 6.23E-109 T 09-03-2017 UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Gene3D G3DSA:1.25.40.20 220 281 7.2E-18 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SUPERFAMILY SSF54427 7 135 1.87E-19 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SUPERFAMILY SSF48403 123 281 8.65E-34 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Gene3D G3DSA:1.25.40.20 142 219 2.2E-21 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Pfam PF13606 Ankyrin repeat 239 263 1.2E-4 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Gene3D G3DSA:3.10.450.50 4 137 2.7E-18 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Pfam PF12680 SnoaL-like domain 10 121 4.2E-7 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SMART SM00248 238 267 0.1 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SMART SM00248 171 200 0.016 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SMART SM00248 204 233 8.1E-5 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS07635 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Pfam PF12796 Ankyrin repeats (3 copies) 143 229 6.1E-13 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS15445 7b29fc26b26e0cb157b86792d6aee074 301 Pfam PF05368 NmrA-like family 8 235 1.2E-47 T 09-03-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_RS15445 7b29fc26b26e0cb157b86792d6aee074 301 Gene3D G3DSA:3.40.50.720 1 230 1.4E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15445 7b29fc26b26e0cb157b86792d6aee074 301 SUPERFAMILY SSF51735 5 241 3.26E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07445 7f90c77a3802edfe24f0107e6fe492a7 550 Pfam PF01547 Bacterial extracellular solute-binding protein 126 366 1.4E-15 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS07445 7f90c77a3802edfe24f0107e6fe492a7 550 SUPERFAMILY SSF53850 33 40 2.64E-54 T 09-03-2017 UA74_RS07445 7f90c77a3802edfe24f0107e6fe492a7 550 SUPERFAMILY SSF53850 97 547 2.64E-54 T 09-03-2017 UA74_RS07445 7f90c77a3802edfe24f0107e6fe492a7 550 Gene3D G3DSA:3.40.190.10 99 235 3.0E-7 T 09-03-2017 UA74_RS07445 7f90c77a3802edfe24f0107e6fe492a7 550 Gene3D G3DSA:3.40.190.10 236 417 1.4E-24 T 09-03-2017 UA74_RS07445 7f90c77a3802edfe24f0107e6fe492a7 550 Gene3D G3DSA:3.40.190.10 497 547 1.4E-24 T 09-03-2017 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 Gene3D G3DSA:3.10.20.30 430 492 1.5E-25 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 Gene3D G3DSA:3.30.460.10 217 363 4.5E-46 T 09-03-2017 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 Pfam PF13291 ACT domain 688 764 2.3E-16 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 SMART SM00954 274 384 1.6E-61 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 Gene3D G3DSA:3.30.70.260 690 762 5.9E-14 T 09-03-2017 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 SUPERFAMILY SSF109604 43 229 1.15E-69 T 09-03-2017 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 Pfam PF02824 TGS domain 431 490 7.3E-24 T 09-03-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 SUPERFAMILY SSF81301 231 408 1.13E-60 T 09-03-2017 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 Pfam PF04607 Region found in RelA / SpoT proteins 274 383 1.5E-36 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 SMART SM00471 82 192 2.2E-12 T 09-03-2017 IPR003607 HD/PDEase domain UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 Pfam PF13328 HD domain 67 214 7.5E-48 T 09-03-2017 IPR003607 HD/PDEase domain UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 SUPERFAMILY SSF55021 688 767 2.25E-14 T 09-03-2017 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 67 764 2.9E-264 T 09-03-2017 IPR004811 RelA/SpoT family GO:0015969 UA74_RS11170 709105344b2fa152d724c90dcf1e8799 769 SUPERFAMILY SSF81271 418 490 4.58E-23 T 09-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UA74_RS26335 95fd8e0f1243a78b699dd1d23125aae1 328 SUPERFAMILY SSF51679 1 318 5.1E-73 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS26335 95fd8e0f1243a78b699dd1d23125aae1 328 Pfam PF00296 Luciferase-like monooxygenase 1 295 2.6E-55 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS26335 95fd8e0f1243a78b699dd1d23125aae1 328 Gene3D G3DSA:3.20.20.30 1 318 6.0E-80 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 Gene3D G3DSA:1.10.230.10 244 339 5.2E-28 T 09-03-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 Gene3D G3DSA:1.10.580.10 20 243 2.5E-66 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 Pfam PF00285 Citrate synthase, C-terminal domain 14 370 8.0E-106 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 186 201 5.4E-35 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 208 236 5.4E-35 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 261 281 5.4E-35 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 320 336 5.4E-35 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 340 354 5.4E-35 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 137 150 5.4E-35 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 PIRSF PIRSF001369 6 384 1.4E-101 T 09-03-2017 IPR024176 Citrate synthase, bacterial-type UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 SUPERFAMILY SSF48256 10 378 7.98E-109 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14255 caf32a63c4e85200f83eb79653322177 385 ProSitePatterns PS00480 Citrate synthase signature. 268 280 - T 09-03-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 283 299 6.0E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 166 176 6.0E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 314 334 6.0E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 2 15 6.0E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 107 127 6.0E-7 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 Pfam PF00012 Hsp70 protein 102 324 2.6E-23 T 09-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 286 300 - T 09-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 Gene3D G3DSA:3.30.420.40 166 313 5.2E-15 T 09-03-2017 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 SUPERFAMILY SSF53067 4 146 4.86E-20 T 09-03-2017 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 Gene3D G3DSA:3.30.420.40 4 165 1.6E-20 T 09-03-2017 UA74_RS19115 9830fe66b4ae1c4eacc09d327c5e112c 589 SUPERFAMILY SSF53067 155 325 2.66E-27 T 09-03-2017 UA74_RS07460 bdf22feba5913c40f5b643044548f65a 354 SUPERFAMILY SSF51726 3 347 1.96E-49 T 09-03-2017 UA74_RS07460 bdf22feba5913c40f5b643044548f65a 354 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 3 321 3.5E-13 T 09-03-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS07460 bdf22feba5913c40f5b643044548f65a 354 Gene3D G3DSA:3.20.20.210 3 352 4.2E-65 T 09-03-2017 UA74_RS28630 628ae1fe74eaca0b073812474c04eab5 140 SUPERFAMILY SSF103196 5 129 1.48E-34 T 09-03-2017 UA74_RS28630 628ae1fe74eaca0b073812474c04eab5 140 SMART SM00960 12 102 6.7E-33 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS28630 628ae1fe74eaca0b073812474c04eab5 140 Pfam PF03259 Roadblock/LC7 domain 13 102 2.8E-24 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS28630 628ae1fe74eaca0b073812474c04eab5 140 Gene3D G3DSA:3.30.450.30 12 126 1.4E-26 T 09-03-2017 UA74_RS10650 0083c67c74f9090e9b7fee9ea6bb67dd 279 SMART SM00382 36 260 5.0E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10650 0083c67c74f9090e9b7fee9ea6bb67dd 279 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS10650 0083c67c74f9090e9b7fee9ea6bb67dd 279 SUPERFAMILY SSF52540 13 242 3.55E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10650 0083c67c74f9090e9b7fee9ea6bb67dd 279 Pfam PF00005 ABC transporter 29 176 1.3E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS10650 0083c67c74f9090e9b7fee9ea6bb67dd 279 Gene3D G3DSA:3.40.50.300 13 248 5.3E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 SMART SM00422 1 69 6.8E-20 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 SUPERFAMILY SSF46955 1 113 1.61E-28 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 Pfam PF13411 MerR HTH family regulatory protein 1 67 2.0E-19 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 Gene3D G3DSA:1.10.1660.10 1 113 2.9E-31 T 09-03-2017 UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.6E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.6E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15610 c410ff044403d95649392d6a4c4d0837 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.6E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 SUPERFAMILY SSF55326 15 177 1.5E-44 T 09-03-2017 UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 Pfam PF02769 AIR synthase related protein, C-terminal domain 184 351 1.8E-34 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 SUPERFAMILY SSF56042 180 351 6.43E-55 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 Gene3D G3DSA:3.90.650.10 180 349 1.2E-62 T 09-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 Pfam PF00586 AIR synthase related protein, N-terminal domain 69 172 9.1E-16 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 15 344 1.8E-135 T 09-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 14 361 41.877 T 09-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_RS29390 66e404e86cd93ba6b606cc35e8c5c2f7 370 Gene3D G3DSA:3.30.1330.10 30 177 3.8E-52 T 09-03-2017 IPR016188 PurM-like, N-terminal domain UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 SUPERFAMILY SSF51419 65 334 4.65E-71 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 54 472 37.718 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 341 448 8.3E-14 T 09-03-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01181 Diaminopimelate decarboxylase signature 356 374 1.7E-23 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01181 Diaminopimelate decarboxylase signature 202 211 1.7E-23 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01181 Diaminopimelate decarboxylase signature 113 130 1.7E-23 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01181 Diaminopimelate decarboxylase signature 439 461 1.7E-23 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 95 113 - T 09-03-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 46 472 7.4E-139 T 09-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 230 243 7.3E-16 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 429 442 7.3E-16 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 95 113 7.3E-16 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 115 127 7.3E-16 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 323 342 7.3E-16 T 09-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 269 286 - T 09-03-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 72 333 8.5E-61 T 09-03-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 Gene3D G3DSA:2.40.37.10 314 472 2.2E-46 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 Gene3D G3DSA:3.20.20.10 75 313 3.5E-74 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS07070 c1a38d8de785accb8e119859936fc53f 473 SUPERFAMILY SSF50621 308 472 2.72E-45 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_RS29000 93f05aea3ff942c283ea319fe9695160 219 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 126 4.8E-11 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_RS29000 93f05aea3ff942c283ea319fe9695160 219 SUPERFAMILY SSF102588 12 211 5.49E-28 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS29000 93f05aea3ff942c283ea319fe9695160 219 Gene3D G3DSA:3.40.50.10320 11 211 2.7E-31 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS09665 cd4b09cac13a1d2167052229847dbc22 364 Gene3D G3DSA:1.10.8.300 227 333 5.7E-32 T 09-03-2017 UA74_RS09665 cd4b09cac13a1d2167052229847dbc22 364 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 64 193 2.6E-62 T 09-03-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_RS09665 cd4b09cac13a1d2167052229847dbc22 364 SUPERFAMILY SSF52540 42 308 1.65E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09665 cd4b09cac13a1d2167052229847dbc22 364 Gene3D G3DSA:3.40.50.300 47 209 2.0E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09665 cd4b09cac13a1d2167052229847dbc22 364 PIRSF PIRSF002849 4 338 2.5E-129 T 09-03-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted UA74_RS25325 ca7f068b462a0900245f02124abdb18e 287 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 27 287 8.5E-92 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_RS25325 ca7f068b462a0900245f02124abdb18e 287 Pfam PF02548 Ketopantoate hydroxymethyltransferase 25 281 5.3E-109 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_RS25325 ca7f068b462a0900245f02124abdb18e 287 PIRSF PIRSF000388 17 287 1.0E-110 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_RS25325 ca7f068b462a0900245f02124abdb18e 287 Gene3D G3DSA:3.20.20.60 24 287 2.2E-112 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS25325 ca7f068b462a0900245f02124abdb18e 287 SUPERFAMILY SSF51621 25 285 5.1E-103 T 09-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 UA74_RS25325 ca7f068b462a0900245f02124abdb18e 287 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 26 286 42.555 T 09-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_RS18110 9eb6a9b22a18229b9f290c269129cb5c 364 Gene3D G3DSA:3.20.20.70 1 358 6.1E-111 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS18110 9eb6a9b22a18229b9f290c269129cb5c 364 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 16 336 7.3E-68 T 09-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 UA74_RS18110 9eb6a9b22a18229b9f290c269129cb5c 364 SUPERFAMILY SSF51395 1 358 8.9E-102 T 09-03-2017 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 Pfam PF01341 Glycosyl hydrolases family 6 72 416 4.4E-88 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PIRSF PIRSF001100 4 466 1.2E-103 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 Gene3D G3DSA:3.20.20.40 46 466 2.2E-114 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 SUPERFAMILY SSF51989 50 466 2.35E-95 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 70 89 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 153 168 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 225 238 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 393 407 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 265 275 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 121 134 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 370 390 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS06700 3511e12eda41ae176a33f14956fbca40 466 PRINTS PR00733 Glycosyl hydrolase family 6 signature 329 342 9.5E-38 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS03985 8dc7f561d5069695155d82c709aec39c 400 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 23 392 1.9E-128 T 09-03-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 UA74_RS03985 8dc7f561d5069695155d82c709aec39c 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 304 1.1E-83 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS03985 8dc7f561d5069695155d82c709aec39c 400 Gene3D G3DSA:3.40.50.1100 71 319 9.1E-74 T 09-03-2017 UA74_RS03985 8dc7f561d5069695155d82c709aec39c 400 SUPERFAMILY SSF53686 7 311 1.7E-94 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS03985 8dc7f561d5069695155d82c709aec39c 400 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 09-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UA74_RS23790 0241a4a066ee5ec743e940a3c05b35f3 141 SUPERFAMILY SSF51316 12 140 1.1E-53 T 09-03-2017 IPR011057 Mss4-like UA74_RS23790 0241a4a066ee5ec743e940a3c05b35f3 141 Pfam PF01641 SelR domain 17 136 1.2E-50 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UA74_RS23790 0241a4a066ee5ec743e940a3c05b35f3 141 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 13 139 4.8E-48 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UA74_RS23790 0241a4a066ee5ec743e940a3c05b35f3 141 Gene3D G3DSA:2.170.150.20 8 140 1.3E-57 T 09-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SUPERFAMILY SSF46894 2 87 1.19E-10 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SMART SM00862 11 87 1.3E-6 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SUPERFAMILY SSF48452 89 257 2.47E-26 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SMART SM00028 832 865 5.2 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SMART SM00028 872 905 59.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SMART SM00028 792 825 33.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SMART SM00028 752 785 69.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SMART SM00028 712 745 17.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Pfam PF13424 Tetratricopeptide repeat 754 822 2.4E-9 T 09-03-2017 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SMART SM01043 94 236 2.2E-38 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Pfam PF13176 Tetratricopeptide repeat 834 858 0.031 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Pfam PF00931 NB-ARC domain 285 530 3.5E-12 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Pfam PF13374 Tetratricopeptide repeat 712 744 4.3E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Gene3D G3DSA:1.25.40.10 584 595 2.1E-28 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Gene3D G3DSA:1.25.40.10 669 909 2.1E-28 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 PRINTS PR00364 Disease resistance protein signature 368 382 2.3E-8 T 09-03-2017 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 PRINTS PR00364 Disease resistance protein signature 289 304 2.3E-8 T 09-03-2017 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 PRINTS PR00364 Disease resistance protein signature 456 470 2.3E-8 T 09-03-2017 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Gene3D G3DSA:1.10.10.10 7 90 1.5E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SUPERFAMILY SSF52540 256 526 3.04E-23 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 SUPERFAMILY SSF48452 706 912 1.23E-27 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Pfam PF00486 Transcriptional regulatory protein, C terminal 18 86 2.4E-5 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS14005 1a8cec36bda68738320f81cfeb907903 920 Pfam PF03704 Bacterial transcriptional activator domain 94 236 2.0E-33 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS09840 da7993df6e7299a02790b7befd31210e 177 Pfam PF03703 Bacterial PH domain 87 146 2.1E-15 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS07270 28b276eaabf375a73eb9a7c2f54709cf 332 Pfam PF02733 Dak1 domain 18 327 6.8E-127 T 09-03-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_RS07270 28b276eaabf375a73eb9a7c2f54709cf 332 Gene3D G3DSA:3.40.50.10440 11 181 1.6E-70 T 09-03-2017 UA74_RS07270 28b276eaabf375a73eb9a7c2f54709cf 332 Gene3D G3DSA:3.30.1180.20 184 331 7.0E-55 T 09-03-2017 UA74_RS07270 28b276eaabf375a73eb9a7c2f54709cf 332 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 328 2.8E-142 T 09-03-2017 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 UA74_RS07270 28b276eaabf375a73eb9a7c2f54709cf 332 SUPERFAMILY SSF82549 11 331 5.75E-122 T 09-03-2017 UA74_RS04980 5f9897832c6a8935622fc713d459b028 319 Gene3D G3DSA:3.20.20.30 16 314 2.7E-48 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS04980 5f9897832c6a8935622fc713d459b028 319 SUPERFAMILY SSF51679 18 313 4.37E-42 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS04980 5f9897832c6a8935622fc713d459b028 319 Pfam PF00296 Luciferase-like monooxygenase 17 293 8.8E-38 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 Gene3D G3DSA:3.40.50.300 2 222 6.9E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 Gene3D G3DSA:3.40.50.300 255 485 1.5E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 SMART SM00382 279 472 9.8E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 SMART SM00382 30 217 3.0E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 SUPERFAMILY SSF52540 4 222 2.76E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 SUPERFAMILY SSF52540 262 478 3.61E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 Pfam PF00005 ABC transporter 271 423 7.2E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00980 c10bdc723975899ce0268130f2bbe77a 500 Pfam PF00005 ABC transporter 21 170 6.3E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS07450 e447cbb0a7a63ca32bd1a3c2c79ff1a2 305 SUPERFAMILY SSF161098 59 286 4.06E-48 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07450 e447cbb0a7a63ca32bd1a3c2c79ff1a2 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 233 9.6E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07450 e447cbb0a7a63ca32bd1a3c2c79ff1a2 305 Gene3D G3DSA:1.10.3720.10 6 289 2.2E-43 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21935 3db43d9dc73199bca0befd214c219975 321 SUPERFAMILY SSF46785 5 63 6.33E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21935 3db43d9dc73199bca0befd214c219975 321 Gene3D G3DSA:1.10.10.10 1 63 1.0E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21935 3db43d9dc73199bca0befd214c219975 321 Pfam PF08279 HTH domain 8 60 4.9E-15 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS21935 3db43d9dc73199bca0befd214c219975 321 Pfam PF13280 WYL domain 140 316 1.3E-40 T 09-03-2017 IPR026881 WYL domain UA74_RS14010 213f1e4892d44c7693f648e64b29d79d 270 Pfam PF04672 S-adenosyl methyltransferase 14 256 9.2E-77 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS14010 213f1e4892d44c7693f648e64b29d79d 270 SUPERFAMILY SSF53335 23 262 7.88E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14010 213f1e4892d44c7693f648e64b29d79d 270 PIRSF PIRSF017393 3 270 1.2E-80 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS14010 213f1e4892d44c7693f648e64b29d79d 270 Gene3D G3DSA:3.40.50.150 10 261 5.5E-86 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07480 6acaf28d71d41a467012f4e5686ca61c 318 SUPERFAMILY SSF56059 131 312 4.09E-21 T 09-03-2017 UA74_RS07480 6acaf28d71d41a467012f4e5686ca61c 318 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 313 5.8E-117 T 09-03-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family UA74_RS14550 bb271c40cb9af53fdba4387e998de4d5 342 Gene3D G3DSA:3.40.50.1980 60 178 5.9E-26 T 09-03-2017 UA74_RS14550 bb271c40cb9af53fdba4387e998de4d5 342 SUPERFAMILY SSF53807 46 330 4.71E-45 T 09-03-2017 UA74_RS14550 bb271c40cb9af53fdba4387e998de4d5 342 Gene3D G3DSA:3.40.50.1980 179 307 8.3E-18 T 09-03-2017 UA74_RS14550 bb271c40cb9af53fdba4387e998de4d5 342 Pfam PF01497 Periplasmic binding protein 63 299 4.5E-19 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 370 447 9.2E-16 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 131 1.9E-29 T 09-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF55957 365 448 5.62E-18 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 251 1.3E-24 T 09-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF53738 7 121 1.18E-31 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.40.120.10 9 132 2.4E-29 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.40.120.10 171 247 2.6E-30 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF53738 151 253 2.16E-28 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 363 1.0E-25 T 09-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF53738 257 361 1.84E-29 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 246 6.4E-21 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 202 215 6.4E-21 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 168 187 6.4E-21 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 6.4E-21 T 09-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.30.310.50 366 448 7.1E-22 T 09-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS26790 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.40.120.10 248 365 1.9E-36 T 09-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_RS19425 fddc78f332afebdf4ec95a383057bcaf 571 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS19425 fddc78f332afebdf4ec95a383057bcaf 571 SUPERFAMILY SSF52016 371 558 3.06E-55 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS19425 fddc78f332afebdf4ec95a383057bcaf 571 SUPERFAMILY SSF143975 3 368 1.44E-111 T 09-03-2017 UA74_RS19425 fddc78f332afebdf4ec95a383057bcaf 571 Pfam PF00920 Dehydratase family 36 552 3.1E-167 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Pfam PF12705 PD-(D/E)XK nuclease superfamily 953 1107 1.3E-13 T 09-03-2017 UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Pfam PF13361 UvrD-like helicase C-terminal domain 417 510 5.3E-7 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Pfam PF13361 UvrD-like helicase C-terminal domain 634 764 6.4E-16 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Gene3D G3DSA:3.40.50.300 239 341 2.6E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Gene3D G3DSA:3.40.50.300 118 180 2.6E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Gene3D G3DSA:3.40.50.300 21 85 2.6E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Gene3D G3DSA:1.10.486.10 473 636 7.5E-18 T 09-03-2017 UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 SUPERFAMILY SSF52540 545 695 1.06E-104 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 SUPERFAMILY SSF52540 229 509 1.06E-104 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 SUPERFAMILY SSF52540 743 788 1.06E-104 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 SUPERFAMILY SSF52540 21 197 1.06E-104 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Gene3D G3DSA:3.40.50.300 358 472 1.2E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Gene3D G3DSA:3.40.50.300 739 787 1.2E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Gene3D G3DSA:3.40.50.300 658 693 1.2E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 Pfam PF00580 UvrD/REP helicase N-terminal domain 22 339 3.0E-44 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS04810 00a8ded562d4c9933dde262a29d5d7a9 1132 SUPERFAMILY SSF52980 957 1091 2.09E-7 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 SMART SM00382 367 533 1.1E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 SMART SM00382 30 215 8.3E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 Pfam PF12848 ABC transporter 209 266 1.0E-4 T 09-03-2017 IPR032781 ABC-transporter extension domain UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 SUPERFAMILY SSF52540 6 221 3.55E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 Pfam PF00005 ABC transporter 360 489 1.3E-17 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 Pfam PF00005 ABC transporter 23 171 1.0E-18 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 SUPERFAMILY SSF52540 335 537 1.09E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 Gene3D G3DSA:3.40.50.300 359 537 9.7E-32 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14765 d8881d4830a26b93590a015fa4316016 545 Gene3D G3DSA:3.40.50.300 8 261 9.3E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 21 184 2.1E-30 T 09-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 SUPERFAMILY SSF48179 283 487 7.14E-50 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 PRINTS PR00084 Mannitol dehydrogenase signature 22 32 1.6E-12 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 PRINTS PR00084 Mannitol dehydrogenase signature 248 263 1.6E-12 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 PRINTS PR00084 Mannitol dehydrogenase signature 175 188 1.6E-12 T 09-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 Gene3D G3DSA:3.40.50.720 11 281 1.1E-86 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 217 442 6.6E-66 T 09-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 Gene3D G3DSA:1.10.1040.10 283 487 3.4E-56 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 SUPERFAMILY SSF51735 8 281 6.3E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22260 922d9b648ccbd80398dd86947e56f02f 491 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 218 230 - T 09-03-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_RS23080 9844f9a89a573a94da27b9e389e8651e 165 ProSitePatterns PS00893 Nudix box signature. 46 67 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS23080 9844f9a89a573a94da27b9e389e8651e 165 Pfam PF00293 NUDIX domain 11 136 1.1E-20 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS23080 9844f9a89a573a94da27b9e389e8651e 165 PRINTS PR00502 NUDIX hydrolase family signature 55 70 1.9E-6 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS23080 9844f9a89a573a94da27b9e389e8651e 165 PRINTS PR00502 NUDIX hydrolase family signature 41 55 1.9E-6 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS23080 9844f9a89a573a94da27b9e389e8651e 165 Gene3D G3DSA:3.90.79.10 8 155 2.7E-29 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS23080 9844f9a89a573a94da27b9e389e8651e 165 SUPERFAMILY SSF55811 8 152 2.57E-27 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS21735 b138a5de9512b4c8a58935f839d5dd4b 562 Pfam PF03235 Protein of unknown function DUF262 22 212 4.0E-26 T 09-03-2017 IPR004919 Domain of unknown function DUF262 UA74_RS20900 f924dae11989b7fda6bcc1f2b04f364d 687 SUPERFAMILY SSF52540 423 660 5.6E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20900 f924dae11989b7fda6bcc1f2b04f364d 687 Gene3D G3DSA:3.40.50.300 424 612 2.4E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20900 f924dae11989b7fda6bcc1f2b04f364d 687 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 473 597 7.2E-23 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS20900 f924dae11989b7fda6bcc1f2b04f364d 687 SMART SM00382 468 596 1.2E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 221 1.0E-24 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 SUPERFAMILY SSF52172 4 122 3.84E-40 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 Gene3D G3DSA:3.40.50.2300 4 121 6.5E-39 T 09-03-2017 UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 SUPERFAMILY SSF46894 124 223 1.42E-26 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 Gene3D G3DSA:1.10.10.10 123 223 2.0E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 SMART SM00448 2 113 3.3E-39 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 SMART SM00862 143 221 1.5E-25 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS27020 b572f9aa5005bab73793f1a7d24139d6 224 Pfam PF00072 Response regulator receiver domain 4 114 1.9E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS10275 7a680ec16860ceb80641e17fc3ab924a 224 Gene3D G3DSA:2.160.10.10 59 205 2.1E-44 T 09-03-2017 UA74_RS10275 7a680ec16860ceb80641e17fc3ab924a 224 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 5.5E-8 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS10275 7a680ec16860ceb80641e17fc3ab924a 224 SUPERFAMILY SSF51161 40 203 9.84E-44 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS03690 5c6a8887656b159b0990b8e0687286dc 315 Pfam PF13624 SurA N-terminal domain 10 114 1.3E-6 T 09-03-2017 UA74_RS03690 5c6a8887656b159b0990b8e0687286dc 315 SUPERFAMILY SSF109998 35 154 1.44E-7 T 09-03-2017 IPR027304 Trigger factor/SurA domain UA74_RS02480 7ef8a188a1a06e1c9bc5962e61746796 388 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 112 385 9.8E-74 T 09-03-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 UA74_RS02480 7ef8a188a1a06e1c9bc5962e61746796 388 SUPERFAMILY SSF56322 8 386 3.01E-81 T 09-03-2017 IPR005801 ADC synthase GO:0009058 UA74_RS02480 7ef8a188a1a06e1c9bc5962e61746796 388 Pfam PF00425 chorismate binding enzyme 129 377 1.2E-67 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal UA74_RS02480 7ef8a188a1a06e1c9bc5962e61746796 388 Gene3D G3DSA:3.60.120.10 32 386 3.7E-82 T 09-03-2017 IPR005801 ADC synthase GO:0009058 UA74_RS24390 cacb914904958c4353988a9b14f8aecb 246 PIRSF PIRSF006648 5 245 9.5E-17 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS24390 cacb914904958c4353988a9b14f8aecb 246 Pfam PF01061 ABC-2 type transporter 6 212 1.2E-23 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS10280 8b0312420007f9604dda82fb29e98d76 253 Pfam PF01925 Sulfite exporter TauE/SafE 7 246 2.5E-27 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 Gene3D G3DSA:3.40.50.2300 3 148 6.8E-34 T 09-03-2017 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 SMART SM00421 148 205 5.6E-22 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 SUPERFAMILY SSF52172 4 181 9.81E-30 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 7.2E-16 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 SMART SM00448 3 116 3.1E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 Pfam PF00072 Response regulator receiver domain 5 117 4.7E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.4E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.4E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.4E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS10580 3a978f8201a9d4f1827458b545b5c85e 222 Gene3D G3DSA:1.10.10.10 149 208 1.0E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19000 a7109eacd12cbef446dcf4cc79fc1f11 272 Gene3D G3DSA:1.10.260.40 11 67 5.1E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS19000 a7109eacd12cbef446dcf4cc79fc1f11 272 Pfam PF13560 Helix-turn-helix domain 10 69 1.3E-12 T 09-03-2017 UA74_RS19000 a7109eacd12cbef446dcf4cc79fc1f11 272 SMART SM00530 13 68 7.2E-11 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS19000 a7109eacd12cbef446dcf4cc79fc1f11 272 SUPERFAMILY SSF47413 6 67 8.45E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02135 d24db47b83c8124acbea9e05a2bd224b 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 4.9E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS02135 d24db47b83c8124acbea9e05a2bd224b 207 SUPERFAMILY SSF46689 13 93 1.51E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS02135 d24db47b83c8124acbea9e05a2bd224b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.1E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS02135 d24db47b83c8124acbea9e05a2bd224b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.1E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS02135 d24db47b83c8124acbea9e05a2bd224b 207 SUPERFAMILY SSF48498 92 202 2.56E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS02135 d24db47b83c8124acbea9e05a2bd224b 207 Gene3D G3DSA:1.10.357.10 15 204 4.5E-41 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22335 86b9052ff6c1b362c63bd27e40b8bd15 265 SMART SM00954 56 179 4.7E-44 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 UA74_RS22335 86b9052ff6c1b362c63bd27e40b8bd15 265 Gene3D G3DSA:1.10.287.860 162 210 2.5E-19 T 09-03-2017 UA74_RS22335 86b9052ff6c1b362c63bd27e40b8bd15 265 Gene3D G3DSA:3.30.460.10 18 159 1.6E-39 T 09-03-2017 UA74_RS22335 86b9052ff6c1b362c63bd27e40b8bd15 265 Pfam PF04607 Region found in RelA / SpoT proteins 56 177 1.7E-35 T 09-03-2017 IPR007685 RelA/SpoT GO:0015969 UA74_RS22335 86b9052ff6c1b362c63bd27e40b8bd15 265 SUPERFAMILY SSF81301 18 213 6.38E-57 T 09-03-2017 UA74_RS08270 9267b534a445071088580a0d9e39b42e 169 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 1 159 1.9E-45 T 09-03-2017 IPR018768 Domain of unknown function DUF2344 UA74_RS08270 9267b534a445071088580a0d9e39b42e 169 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 1 159 1.9E-50 T 09-03-2017 IPR018768 Domain of unknown function DUF2344 UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 Pfam PF07731 Multicopper oxidase 451 584 1.4E-22 T 09-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 SUPERFAMILY SSF49503 24 93 1.1E-21 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 SUPERFAMILY SSF49503 130 202 1.1E-21 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 Gene3D G3DSA:2.60.40.420 450 583 1.9E-27 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 ProSitePatterns PS00079 Multicopper oxidases signature 1. 559 579 - T 09-03-2017 IPR033138 Multicopper oxidases, conserved site UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 Pfam PF07732 Multicopper oxidase 134 200 4.4E-6 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 Pfam PF07732 Multicopper oxidase 58 91 7.5E-5 T 09-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 Gene3D G3DSA:2.60.40.420 135 202 1.2E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 Gene3D G3DSA:2.60.40.420 24 95 1.2E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 SUPERFAMILY SSF49503 529 582 3.21E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 SUPERFAMILY SSF49503 238 277 3.21E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 SUPERFAMILY SSF49503 473 489 3.21E-24 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 Gene3D G3DSA:2.60.40.420 203 332 1.1E-22 T 09-03-2017 IPR008972 Cupredoxin UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 ProSitePatterns PS00080 Multicopper oxidases signature 2. 564 575 - T 09-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_RS11545 023e34195293b98e2dc097d6621b24ee 604 SUPERFAMILY SSF49503 205 332 1.09E-13 T 09-03-2017 IPR008972 Cupredoxin UA74_RS19955 a4f10d3ea6d6aa60a1a3df0202826bcb 250 SUPERFAMILY SSF63380 14 126 5.38E-16 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS19955 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Pfam PF04954 Siderophore-interacting protein 130 245 1.6E-23 T 09-03-2017 IPR007037 Siderophore-interacting protein UA74_RS19955 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Pfam PF08021 Siderophore-interacting FAD-binding domain 22 122 9.7E-10 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting UA74_RS19955 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Gene3D G3DSA:2.40.30.10 18 121 2.1E-17 T 09-03-2017 UA74_RS19955 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Gene3D G3DSA:3.40.50.80 126 246 5.7E-22 T 09-03-2017 UA74_RS19725 f1ebc2e4d8ea621bff30024994ce5ac8 574 SUPERFAMILY SSF82171 16 302 9.81E-11 T 09-03-2017 UA74_RS19725 f1ebc2e4d8ea621bff30024994ce5ac8 574 Pfam PF00326 Prolyl oligopeptidase family 354 558 1.4E-35 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS19725 f1ebc2e4d8ea621bff30024994ce5ac8 574 SUPERFAMILY SSF53474 320 555 2.75E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19725 f1ebc2e4d8ea621bff30024994ce5ac8 574 Gene3D G3DSA:3.40.50.1820 320 557 2.4E-51 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19725 f1ebc2e4d8ea621bff30024994ce5ac8 574 Gene3D G3DSA:2.120.10.30 11 70 2.5E-10 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS19725 f1ebc2e4d8ea621bff30024994ce5ac8 574 Gene3D G3DSA:2.120.10.30 206 300 2.5E-10 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS08100 180934179a0030aefcae17d785338e53 283 Pfam PF13531 Bacterial extracellular solute-binding protein 63 280 3.8E-39 T 09-03-2017 UA74_RS08100 180934179a0030aefcae17d785338e53 283 Gene3D G3DSA:3.40.190.10 60 190 3.0E-38 T 09-03-2017 UA74_RS08100 180934179a0030aefcae17d785338e53 283 SUPERFAMILY SSF53850 62 283 5.27E-53 T 09-03-2017 UA74_RS08100 180934179a0030aefcae17d785338e53 283 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 68 279 8.3E-36 T 09-03-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 UA74_RS08100 180934179a0030aefcae17d785338e53 283 PIRSF PIRSF004846 21 283 5.9E-60 T 09-03-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 UA74_RS26770 cc3100bbd0abeb9adae6532fd4580913 505 Pfam PF13520 Amino acid permease 32 458 5.1E-49 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 UA74_RS26770 cc3100bbd0abeb9adae6532fd4580913 505 PIRSF PIRSF006060 6 500 5.1E-87 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 UA74_RS13905 37fc8fd889e00039c8389e24a33deac6 338 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 332 4.4E-74 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS13905 37fc8fd889e00039c8389e24a33deac6 338 Pfam PF01867 CRISPR associated protein Cas1 8 292 7.5E-84 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS13905 37fc8fd889e00039c8389e24a33deac6 338 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 6 323 23.881 T 09-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_RS02265 506ad68ab35b8ca5b32e909718572b9a 301 Gene3D G3DSA:3.40.50.1000 124 267 1.9E-47 T 09-03-2017 IPR023214 HAD-like domain UA74_RS02265 506ad68ab35b8ca5b32e909718572b9a 301 SUPERFAMILY SSF56784 49 266 1.31E-28 T 09-03-2017 IPR023214 HAD-like domain UA74_RS02265 506ad68ab35b8ca5b32e909718572b9a 301 Pfam PF12710 haloacid dehalogenase-like hydrolase 50 236 6.1E-25 T 09-03-2017 UA74_RS02265 506ad68ab35b8ca5b32e909718572b9a 301 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 49 249 3.0E-54 T 09-03-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial UA74_RS02265 506ad68ab35b8ca5b32e909718572b9a 301 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 49 237 4.4E-17 T 09-03-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 SMART SM01043 778 917 2.5E-17 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 SUPERFAMILY SSF48452 798 929 2.16E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 SMART SM00862 692 771 1.6E-5 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 Gene3D G3DSA:1.10.10.10 697 756 3.8E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 Pfam PF01476 LysM domain 180 229 7.3E-6 T 09-03-2017 IPR018392 LysM domain UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 Pfam PF00486 Transcriptional regulatory protein, C terminal 698 761 1.4E-6 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 SUPERFAMILY SSF46894 673 758 7.94E-9 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS16230 c80e514530f0a751a4b0264df66d6ea8 952 Pfam PF03704 Bacterial transcriptional activator domain 778 916 1.0E-9 T 09-03-2017 IPR005158 Bacterial transcriptional activator domain UA74_RS20205 087ab5372c3f4ef8b7d8543da770dffb 237 Pfam PF06912 Protein of unknown function (DUF1275) 2 214 6.0E-35 T 09-03-2017 IPR010699 Protein of unknown function DUF1275 UA74_RS03075 bf45eed02036b572691f9f8588254774 219 SUPERFAMILY SSF53335 8 198 1.75E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS03075 bf45eed02036b572691f9f8588254774 219 Pfam PF13649 Methyltransferase domain 54 144 7.8E-18 T 09-03-2017 UA74_RS03075 bf45eed02036b572691f9f8588254774 219 Gene3D G3DSA:3.40.50.150 9 188 4.0E-33 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09315 d87c6ef6b37acd2077594d0456c2e1bc 197 Gene3D G3DSA:3.30.300.70 2 87 2.7E-18 T 09-03-2017 IPR028989 Ribosome maturation factor RimP, N-terminal UA74_RS09315 d87c6ef6b37acd2077594d0456c2e1bc 197 SUPERFAMILY SSF74942 91 154 7.45E-5 T 09-03-2017 IPR028998 Ribosome maturation factor RimP, C-terminal UA74_RS09315 d87c6ef6b37acd2077594d0456c2e1bc 197 Pfam PF02576 Putative ribosome maturation factor RimP 5 150 1.8E-23 T 09-03-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 UA74_RS09315 d87c6ef6b37acd2077594d0456c2e1bc 197 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 3 154 19.655 T 09-03-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 UA74_RS09315 d87c6ef6b37acd2077594d0456c2e1bc 197 SUPERFAMILY SSF75420 3 90 4.18E-14 T 09-03-2017 IPR028989 Ribosome maturation factor RimP, N-terminal UA74_RS30080 2d1e38aed47b5ef7bcbd2917ad308e0b 467 Pfam PF01546 Peptidase family M20/M25/M40 89 459 2.4E-21 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS30080 2d1e38aed47b5ef7bcbd2917ad308e0b 467 Gene3D G3DSA:3.30.70.360 214 369 1.9E-23 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS30080 2d1e38aed47b5ef7bcbd2917ad308e0b 467 Pfam PF07687 Peptidase dimerisation domain 201 360 4.9E-10 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS30080 2d1e38aed47b5ef7bcbd2917ad308e0b 467 SUPERFAMILY SSF53187 377 461 1.77E-43 T 09-03-2017 UA74_RS30080 2d1e38aed47b5ef7bcbd2917ad308e0b 467 SUPERFAMILY SSF53187 10 203 1.77E-43 T 09-03-2017 UA74_RS30080 2d1e38aed47b5ef7bcbd2917ad308e0b 467 Gene3D G3DSA:3.40.630.10 8 213 2.9E-45 T 09-03-2017 UA74_RS30080 2d1e38aed47b5ef7bcbd2917ad308e0b 467 Gene3D G3DSA:3.40.630.10 401 462 2.9E-45 T 09-03-2017 UA74_RS00900 c8d3c225b1e79d3ff999b6d5ef9746ac 414 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 253 398 1.0E-18 T 09-03-2017 IPR031475 Putative nucleotide-binding C-terminal domain UA74_RS00900 c8d3c225b1e79d3ff999b6d5ef9746ac 414 SUPERFAMILY SSF142764 10 405 2.48E-45 T 09-03-2017 UA74_RS00900 c8d3c225b1e79d3ff999b6d5ef9746ac 414 Pfam PF07005 Putative sugar-binding N-terminal domain 10 222 2.6E-17 T 09-03-2017 IPR010737 Putative sugar-binding, N-terminal domain UA74_RS21920 b56103195c9c18e142c6dee0808b5d72 386 Gene3D G3DSA:3.30.360.10 165 361 2.7E-39 T 09-03-2017 UA74_RS21920 b56103195c9c18e142c6dee0808b5d72 386 SUPERFAMILY SSF55347 153 287 3.6E-24 T 09-03-2017 UA74_RS21920 b56103195c9c18e142c6dee0808b5d72 386 Gene3D G3DSA:3.40.50.720 1 164 1.1E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21920 b56103195c9c18e142c6dee0808b5d72 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 112 3.3E-26 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS21920 b56103195c9c18e142c6dee0808b5d72 386 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 155 261 1.2E-11 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS21920 b56103195c9c18e142c6dee0808b5d72 386 SUPERFAMILY SSF51735 1 177 1.55E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22690 f4d1db6bb736427305c711460552a9f6 273 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 2 239 4.0E-12 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS22690 f4d1db6bb736427305c711460552a9f6 273 SUPERFAMILY SSF56219 2 136 8.51E-15 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS22690 f4d1db6bb736427305c711460552a9f6 273 SUPERFAMILY SSF56219 177 243 8.51E-15 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS22690 f4d1db6bb736427305c711460552a9f6 273 Gene3D G3DSA:3.60.10.10 87 244 1.2E-6 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS16675 16a99cc3aca27158e0af25a4413123e5 287 Pfam PF00005 ABC transporter 23 161 1.3E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16675 16a99cc3aca27158e0af25a4413123e5 287 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS16675 16a99cc3aca27158e0af25a4413123e5 287 SUPERFAMILY SSF52540 3 221 7.14E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16675 16a99cc3aca27158e0af25a4413123e5 287 Gene3D G3DSA:3.40.50.300 3 226 3.7E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16675 16a99cc3aca27158e0af25a4413123e5 287 SMART SM00382 30 216 4.7E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22520 b9481466dba450a8ced81bb4f2bb91fe 286 Pfam PF00753 Metallo-beta-lactamase superfamily 59 199 1.3E-14 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS22520 b9481466dba450a8ced81bb4f2bb91fe 286 SMART SM00849 55 225 1.6E-9 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS22520 b9481466dba450a8ced81bb4f2bb91fe 286 SUPERFAMILY SSF56281 58 230 1.02E-20 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS22520 b9481466dba450a8ced81bb4f2bb91fe 286 Gene3D G3DSA:3.60.15.10 27 212 6.7E-19 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS18205 c0e36ae2049c44df1698a6db2c5b9c77 275 Gene3D G3DSA:1.10.3720.10 5 262 2.8E-53 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18205 c0e36ae2049c44df1698a6db2c5b9c77 275 SUPERFAMILY SSF161098 4 274 2.8E-63 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18205 c0e36ae2049c44df1698a6db2c5b9c77 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 268 2.9E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Pfam PF08529 NusA N-terminal domain 6 60 1.7E-8 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Pfam PF08529 NusA N-terminal domain 68 100 1.0E-6 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 340 26.119 T 09-03-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF50249 110 179 6.97E-16 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:2.40.50.140 106 178 1.1E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 SMART SM00316 110 180 2.9E-5 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 323 1.8E-105 T 09-03-2017 IPR010213 Transcription termination factor NusA GO:0003723 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:3.30.300.20 258 324 1.4E-30 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF54814 259 323 4.25E-17 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Pfam PF13184 NusA-like KH domain 211 277 1.7E-24 T 09-03-2017 IPR025249 KH domain, NusA-like GO:0003723 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF54814 180 258 7.85E-27 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:3.30.300.20 179 257 5.6E-32 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 SMART SM00322 284 338 1.2 T 09-03-2017 IPR004087 K Homology domain GO:0003676 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 SMART SM00322 210 283 0.47 T 09-03-2017 IPR004087 K Homology domain GO:0003676 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:3.30.1480.10 4 99 3.4E-30 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 UA74_RS09320 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF69705 4 99 2.35E-30 T 09-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 UA74_RS10520 2498c49436d80836ddfe3df5a4693fc4 150 SUPERFAMILY SSF52799 54 142 4.24E-17 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like UA74_RS10520 2498c49436d80836ddfe3df5a4693fc4 150 Gene3D G3DSA:3.90.190.10 57 143 4.1E-17 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like UA74_RS15035 29c4144103b45e6bb361db44d8d72351 311 Gene3D G3DSA:3.40.50.720 31 185 1.7E-25 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15035 29c4144103b45e6bb361db44d8d72351 311 PIRSF PIRSF000103 23 308 4.1E-32 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_RS15035 29c4144103b45e6bb361db44d8d72351 311 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 31 182 2.0E-18 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS15035 29c4144103b45e6bb361db44d8d72351 311 SUPERFAMILY SSF51735 31 185 6.81E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18115 3f47495cb179e9d5138917ea77f304a3 119 Gene3D G3DSA:1.10.1660.10 1 116 1.4E-24 T 09-03-2017 UA74_RS18115 3f47495cb179e9d5138917ea77f304a3 119 Pfam PF13411 MerR HTH family regulatory protein 1 67 3.1E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS18115 3f47495cb179e9d5138917ea77f304a3 119 SUPERFAMILY SSF46955 1 117 1.94E-23 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS18115 3f47495cb179e9d5138917ea77f304a3 119 SMART SM00422 1 69 9.5E-12 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS18115 3f47495cb179e9d5138917ea77f304a3 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.4E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS18115 3f47495cb179e9d5138917ea77f304a3 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.4E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS18115 3f47495cb179e9d5138917ea77f304a3 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.4E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 2.8E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 2.8E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 2.8E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 2.8E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 2.8E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 2.8E-57 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 SMART SM01004 2 322 3.8E-207 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 PIRSF PIRSF001415 1 325 1.3E-141 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 SUPERFAMILY SSF51569 1 324 6.59E-129 T 09-03-2017 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 09-03-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 Gene3D G3DSA:3.20.20.70 2 324 1.2E-138 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS02315 f6d9c4f778c78b6fa2df9704a4466c23 325 Pfam PF00490 Delta-aminolevulinic acid dehydratase 5 321 1.2E-134 T 09-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 Gene3D G3DSA:1.10.10.10 1 83 1.7E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 Gene3D G3DSA:3.40.190.10 178 263 4.5E-23 T 09-03-2017 UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 SUPERFAMILY SSF46785 1 83 4.34E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 Gene3D G3DSA:3.40.190.10 90 177 2.5E-24 T 09-03-2017 UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.6E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.6E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.6E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.6E-22 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 Pfam PF03466 LysR substrate binding domain 88 287 3.2E-43 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS15365 d7e6e13df90a64f76f4a8f5172b50542 298 SUPERFAMILY SSF53850 88 287 3.16E-39 T 09-03-2017 UA74_RS25350 f7cda26010f493bd39a291f264f28fa3 308 Gene3D G3DSA:3.30.2010.10 106 163 1.8E-10 T 09-03-2017 UA74_RS25350 f7cda26010f493bd39a291f264f28fa3 308 Pfam PF01435 Peptidase family M48 98 300 1.4E-21 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UA74_RS05665 b365c042623161730392babe2ab64d46 408 Pfam PF13560 Helix-turn-helix domain 7 62 5.4E-9 T 09-03-2017 UA74_RS05665 b365c042623161730392babe2ab64d46 408 SMART SM00530 9 64 9.8E-8 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS05665 b365c042623161730392babe2ab64d46 408 Gene3D G3DSA:1.10.260.40 5 64 1.0E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05665 b365c042623161730392babe2ab64d46 408 SUPERFAMILY SSF47413 5 64 4.79E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24855 e9ebcbdfb202f2dfba6a2827ec33c5e6 923 Pfam PF03639 Glycosyl hydrolase family 81 32 664 1.6E-63 T 09-03-2017 IPR005200 Endo-1,3(4)-beta-glucanase GO:0052861 UA74_RS09110 c45dc569be027e238e088b93edfb0bc5 401 Pfam PF02163 Peptidase family M50 10 350 2.9E-48 T 09-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 UA74_RS09110 c45dc569be027e238e088b93edfb0bc5 401 Gene3D G3DSA:2.30.42.10 94 214 1.9E-14 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS09110 c45dc569be027e238e088b93edfb0bc5 401 SUPERFAMILY SSF50156 106 212 1.33E-8 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 SUPERFAMILY SSF69618 17 274 4.58E-55 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 Pfam PF02602 Uroporphyrinogen-III synthase HemD 29 270 4.3E-41 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 Gene3D G3DSA:3.40.50.10090 145 278 5.7E-34 T 09-03-2017 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 Gene3D G3DSA:3.40.50.10090 14 142 5.0E-31 T 09-03-2017 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 SUPERFAMILY SSF46894 284 373 2.75E-10 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 Pfam PF00486 Transcriptional regulatory protein, C terminal 312 371 1.4E-9 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 SMART SM00862 301 371 2.8E-11 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS09445 5bc02bf3e09e54574adf22adce43e4b6 376 Gene3D G3DSA:1.10.10.10 289 373 4.4E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01520 e7efd0d2afa7e7679448951de8095845 209 Gene3D G3DSA:3.30.1130.10 77 207 2.3E-58 T 09-03-2017 UA74_RS01520 e7efd0d2afa7e7679448951de8095845 209 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 30 208 8.8E-70 T 09-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 UA74_RS01520 e7efd0d2afa7e7679448951de8095845 209 Pfam PF01227 GTP cyclohydrolase I 29 206 1.0E-74 T 09-03-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 UA74_RS01520 e7efd0d2afa7e7679448951de8095845 209 Gene3D G3DSA:1.10.286.10 23 74 1.9E-23 T 09-03-2017 UA74_RS01520 e7efd0d2afa7e7679448951de8095845 209 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 24 207 41.436 T 09-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 UA74_RS01520 e7efd0d2afa7e7679448951de8095845 209 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 134 144 - T 09-03-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 UA74_RS01520 e7efd0d2afa7e7679448951de8095845 209 SUPERFAMILY SSF55620 20 207 8.15E-77 T 09-03-2017 UA74_RS27980 0a507d775c5dec42a41bbef4b3f53094 300 Gene3D G3DSA:1.10.10.10 1 87 9.6E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27980 0a507d775c5dec42a41bbef4b3f53094 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.9E-17 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS27980 0a507d775c5dec42a41bbef4b3f53094 300 Pfam PF03466 LysR substrate binding domain 88 294 1.9E-39 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS27980 0a507d775c5dec42a41bbef4b3f53094 300 Gene3D G3DSA:3.40.190.10 179 266 2.3E-27 T 09-03-2017 UA74_RS27980 0a507d775c5dec42a41bbef4b3f53094 300 Gene3D G3DSA:3.40.190.10 89 178 1.2E-17 T 09-03-2017 UA74_RS27980 0a507d775c5dec42a41bbef4b3f53094 300 SUPERFAMILY SSF46785 1 112 1.59E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27980 0a507d775c5dec42a41bbef4b3f53094 300 SUPERFAMILY SSF53850 90 298 1.38E-34 T 09-03-2017 UA74_RS00875 c623aa34033f21a8f7bc84362f70005c 130 Pfam PF00583 Acetyltransferase (GNAT) family 19 107 5.5E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS00875 c623aa34033f21a8f7bc84362f70005c 130 SUPERFAMILY SSF55729 20 110 3.09E-19 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS00875 c623aa34033f21a8f7bc84362f70005c 130 Gene3D G3DSA:3.40.630.30 24 110 8.8E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 Pfam PF00561 alpha/beta hydrolase fold 20 269 6.5E-20 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 224 240 1.4E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 100 113 1.4E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 257 279 1.4E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 45 60 1.4E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 3.0E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.0E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 3.0E-7 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 Gene3D G3DSA:3.40.50.1820 2 282 4.1E-55 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15565 200a6b5bdbd877c3a164439fccf0905a 286 SUPERFAMILY SSF53474 2 282 3.13E-54 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23985 86b49b3fc7238dc8ce00000163953796 191 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 129 2.0E-12 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_RS23985 86b49b3fc7238dc8ce00000163953796 191 SUPERFAMILY SSF109854 3 135 3.43E-19 T 09-03-2017 UA74_RS23985 86b49b3fc7238dc8ce00000163953796 191 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 11 185 7.6E-41 T 09-03-2017 IPR017520 Conserved hypothetical protein CHP03086 UA74_RS23985 86b49b3fc7238dc8ce00000163953796 191 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 165 7.5E-20 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_RS02490 92dafad319b6d7ada51d3862f9fe538f 252 Gene3D G3DSA:3.30.540.10 15 151 5.6E-23 T 09-03-2017 UA74_RS02490 92dafad319b6d7ada51d3862f9fe538f 252 Pfam PF00459 Inositol monophosphatase family 17 227 9.4E-20 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02490 92dafad319b6d7ada51d3862f9fe538f 252 Gene3D G3DSA:3.40.190.80 179 247 5.1E-4 T 09-03-2017 UA74_RS02490 92dafad319b6d7ada51d3862f9fe538f 252 SUPERFAMILY SSF56655 15 249 2.75E-31 T 09-03-2017 UA74_RS02490 92dafad319b6d7ada51d3862f9fe538f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 90 106 3.5E-5 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02490 92dafad319b6d7ada51d3862f9fe538f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 48 68 3.5E-5 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS14670 3cb4dd03b4853710fa68442738464f2f 341 Gene3D G3DSA:3.40.50.1100 29 126 6.8E-15 T 09-03-2017 UA74_RS14670 3cb4dd03b4853710fa68442738464f2f 341 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 30 279 2.5E-28 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS14670 3cb4dd03b4853710fa68442738464f2f 341 SUPERFAMILY SSF53686 28 294 3.8E-42 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS14670 3cb4dd03b4853710fa68442738464f2f 341 Gene3D G3DSA:3.40.50.1100 127 296 9.8E-24 T 09-03-2017 UA74_RS25830 d8dd774ea124f1fea0fdee1f5b9d49cb 422 SUPERFAMILY SSF53335 187 395 2.59E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS25830 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Pfam PF08241 Methyltransferase domain 234 327 9.0E-22 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS25830 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Gene3D G3DSA:3.40.50.150 192 389 5.3E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS25830 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Gene3D G3DSA:3.30.460.10 28 191 8.4E-54 T 09-03-2017 UA74_RS25830 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Pfam PF04229 GrpB protein 29 187 5.4E-51 T 09-03-2017 IPR007344 GrpB/Dephospho-CoA kinase UA74_RS25830 d8dd774ea124f1fea0fdee1f5b9d49cb 422 SUPERFAMILY SSF81301 31 190 9.15E-48 T 09-03-2017 UA74_RS04640 f6117f41eb1768d8a5d659185e9b3603 384 SUPERFAMILY SSF52540 119 365 3.09E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04640 f6117f41eb1768d8a5d659185e9b3603 384 Gene3D G3DSA:3.40.50.300 112 364 6.3E-85 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04640 f6117f41eb1768d8a5d659185e9b3603 384 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 120 365 8.0E-88 T 09-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein UA74_RS04640 f6117f41eb1768d8a5d659185e9b3603 384 SUPERFAMILY SSF117916 14 97 5.23E-22 T 09-03-2017 UA74_RS04640 f6117f41eb1768d8a5d659185e9b3603 384 Hamap MF_02040 Iron-sulfur cluster carrier protein. 111 366 33.288 T 09-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein UA74_RS04640 f6117f41eb1768d8a5d659185e9b3603 384 Pfam PF01883 Domain of unknown function DUF59 15 85 5.1E-18 T 09-03-2017 IPR002744 Domain of unknown function DUF59 UA74_RS04640 f6117f41eb1768d8a5d659185e9b3603 384 ProSitePatterns PS01215 Mrp family signature. 224 240 - T 09-03-2017 IPR000808 Mrp, conserved site GO:0005524 UA74_RS10970 dbd9510b16a3262185129bf1294c37b7 287 Gene3D G3DSA:3.20.20.30 1 285 2.7E-56 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS10970 dbd9510b16a3262185129bf1294c37b7 287 SUPERFAMILY SSF51679 1 285 5.23E-53 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS10970 dbd9510b16a3262185129bf1294c37b7 287 Pfam PF00296 Luciferase-like monooxygenase 5 261 1.5E-37 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS21850 22c3b7fa1754907ea8253f23a8217486 414 Gene3D G3DSA:3.40.630.30 152 257 7.5E-7 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS21850 22c3b7fa1754907ea8253f23a8217486 414 Pfam PF13527 Acetyltransferase (GNAT) domain 20 144 1.6E-15 T 09-03-2017 UA74_RS21850 22c3b7fa1754907ea8253f23a8217486 414 Gene3D G3DSA:3.40.630.30 14 145 8.5E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS21850 22c3b7fa1754907ea8253f23a8217486 414 SUPERFAMILY SSF55729 17 256 3.62E-31 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09710 3870ece0908c1794d1c04a4677507d26 357 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 346 23.115 T 09-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS09710 3870ece0908c1794d1c04a4677507d26 357 ProSitePatterns PS01348 MraY family signature 2. 175 186 - T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS09710 3870ece0908c1794d1c04a4677507d26 357 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 8.6E-6 T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS09710 3870ece0908c1794d1c04a4677507d26 357 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 09-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS09710 3870ece0908c1794d1c04a4677507d26 357 Pfam PF00953 Glycosyl transferase family 4 82 272 5.4E-38 T 09-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 UA74_RS09710 3870ece0908c1794d1c04a4677507d26 357 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 342 6.8E-92 T 09-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:3.30.559.10 336 570 2.9E-81 T 09-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF51230 1 96 2.75E-27 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 153 182 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF47005 266 311 2.62E-12 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:2.40.50.100 129 221 8.3E-30 T 09-03-2017 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:2.40.50.100 1 95 9.5E-31 T 09-03-2017 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF51230 130 222 1.01E-26 T 09-03-2017 IPR011053 Single hybrid motif UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF02817 e3 binding domain 273 307 7.9E-15 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 579 3.0E-262 T 09-03-2017 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF00364 Biotin-requiring enzyme 5 76 1.4E-21 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF00364 Biotin-requiring enzyme 130 201 5.4E-21 T 09-03-2017 IPR000089 Biotin/lipoyl attachment UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 343 570 9.3E-76 T 09-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:4.10.320.10 269 318 1.5E-19 T 09-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF52777 334 570 1.11E-78 T 09-03-2017 UA74_RS25215 15d5326c9a3bd5aa56afeb19975e92a0 579 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 09-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 SUPERFAMILY SSF52540 5 229 3.72E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 Gene3D G3DSA:3.40.50.300 275 485 2.1E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 Gene3D G3DSA:3.40.50.300 4 231 1.0E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 Pfam PF00005 ABC transporter 277 431 1.2E-20 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 Pfam PF00005 ABC transporter 21 171 7.2E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 SUPERFAMILY SSF52540 277 483 3.22E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 SMART SM00382 286 480 0.0049 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS18380 f4ddf48986ce358622918a63230ec0ff 516 SMART SM00382 30 227 2.0E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS09140 eec7f73bd0cbe2850b9fcab8396d72d4 81 SUPERFAMILY SSF143120 5 46 1.22E-9 T 09-03-2017 UA74_RS09140 eec7f73bd0cbe2850b9fcab8396d72d4 81 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 39 3.7E-6 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS09140 eec7f73bd0cbe2850b9fcab8396d72d4 81 Gene3D G3DSA:3.40.1620.10 5 48 1.7E-10 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS09140 eec7f73bd0cbe2850b9fcab8396d72d4 81 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 41 2.7E-9 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS00630 c7bf705ad00848938da09cd512b40767 310 Gene3D G3DSA:3.40.50.720 1 177 1.3E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00630 c7bf705ad00848938da09cd512b40767 310 Gene3D G3DSA:3.90.25.10 178 309 5.2E-29 T 09-03-2017 UA74_RS00630 c7bf705ad00848938da09cd512b40767 310 SUPERFAMILY SSF51735 1 309 2.78E-87 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00630 c7bf705ad00848938da09cd512b40767 310 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 3.3E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15900 c4898a48511a7aa6b20c233666d7a89d 281 Gene3D G3DSA:3.30.70.141 55 195 2.0E-6 T 09-03-2017 UA74_RS15900 c4898a48511a7aa6b20c233666d7a89d 281 SUPERFAMILY SSF54919 53 196 3.14E-13 T 09-03-2017 UA74_RS15900 c4898a48511a7aa6b20c233666d7a89d 281 Pfam PF00334 Nucleoside diphosphate kinase 57 192 8.4E-8 T 09-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_RS12675 f5cf25188750ffe342d98fe84ffe3060 322 Pfam PF07859 alpha/beta hydrolase fold 86 291 6.6E-64 T 09-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 UA74_RS12675 f5cf25188750ffe342d98fe84ffe3060 322 Gene3D G3DSA:3.40.50.1820 31 317 1.4E-84 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12675 f5cf25188750ffe342d98fe84ffe3060 322 SUPERFAMILY SSF53474 57 314 4.24E-69 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 438 448 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 249 2.5E-22 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 PRINTS PR00723 Subtilisin serine protease family (S8) signature 267 280 2.5E-22 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 PRINTS PR00723 Subtilisin serine protease family (S8) signature 437 453 2.5E-22 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 Gene3D G3DSA:3.40.50.200 212 495 2.2E-87 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 Pfam PF00082 Subtilase family 230 487 3.9E-54 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 SUPERFAMILY SSF52743 211 495 3.01E-80 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS20520 4be9b1877ac8631a5e559e70f6250002 1227 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 271 281 - T 09-03-2017 IPR022398 Peptidase S8, subtilisin, His-active site UA74_RS14030 bb6e9220751bff6fde67e416ddaf7b43 301 Pfam PF00722 Glycosyl hydrolases family 16 84 265 4.0E-21 T 09-03-2017 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 UA74_RS14030 bb6e9220751bff6fde67e416ddaf7b43 301 SUPERFAMILY SSF49899 30 301 5.12E-54 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS14030 bb6e9220751bff6fde67e416ddaf7b43 301 Gene3D G3DSA:2.60.120.200 29 300 2.5E-53 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS10210 05b386696fc90e374c4da569b2c5ef91 203 SMART SM01006 21 69 2.1E-13 T 09-03-2017 IPR019432 Siderophore biosynthesis protein, conserved domain UA74_RS10210 05b386696fc90e374c4da569b2c5ef91 203 Gene3D G3DSA:3.40.630.30 8 182 6.7E-52 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS10210 05b386696fc90e374c4da569b2c5ef91 203 Pfam PF13523 Acetyltransferase (GNAT) domain 29 170 1.2E-46 T 09-03-2017 UA74_RS10210 05b386696fc90e374c4da569b2c5ef91 203 SUPERFAMILY SSF55729 8 182 1.24E-46 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS23320 a38bf0afdff5f0fbd53eec2818ef0539 130 SUPERFAMILY SSF50475 7 125 2.29E-27 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS23320 a38bf0afdff5f0fbd53eec2818ef0539 130 Gene3D G3DSA:2.30.110.10 7 125 8.5E-33 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS23320 a38bf0afdff5f0fbd53eec2818ef0539 130 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 83 8.5E-17 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS11145 792e09a0b25029a800eb175b7edc2064 124 Gene3D G3DSA:3.10.180.10 9 121 6.5E-22 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS11145 792e09a0b25029a800eb175b7edc2064 124 SUPERFAMILY SSF54593 1 122 1.02E-27 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS11145 792e09a0b25029a800eb175b7edc2064 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 114 1.0E-9 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS24665 afeafa740f05e80b56018f6625796eb5 91 Gene3D G3DSA:3.40.50.300 1 66 6.0E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24665 afeafa740f05e80b56018f6625796eb5 91 SUPERFAMILY SSF52540 1 64 1.3E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 9 282 6.5E-52 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 Pfam PF08544 GHMP kinases C terminal 213 285 1.4E-8 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 SUPERFAMILY SSF55060 173 293 2.09E-22 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 PIRSF PIRSF010376 8 307 8.0E-81 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 Gene3D G3DSA:3.30.70.890 173 289 1.7E-24 T 09-03-2017 IPR013750 GHMP kinase, C-terminal domain UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 SUPERFAMILY SSF54211 8 167 4.25E-43 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 298 31.638 T 09-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 Pfam PF00288 GHMP kinases N terminal domain 96 154 4.6E-8 T 09-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 UA74_RS03575 a97748067b7fc1dfd53d8ae83fc5f524 321 Gene3D G3DSA:3.30.230.10 9 168 5.9E-51 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS20470 6dee0495ca0954c3fe3d8425aa0aa0a6 262 Pfam PF00929 Exonuclease 15 177 3.6E-10 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS20470 6dee0495ca0954c3fe3d8425aa0aa0a6 262 Gene3D G3DSA:3.30.420.10 6 188 1.5E-33 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS20470 6dee0495ca0954c3fe3d8425aa0aa0a6 262 SMART SM00479 12 187 2.4E-14 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS20470 6dee0495ca0954c3fe3d8425aa0aa0a6 262 SUPERFAMILY SSF53098 8 200 2.55E-39 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS15670 ffba46459e2b52ca0cd749c392e41338 211 Gene3D G3DSA:3.40.50.720 1 206 6.9E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15670 ffba46459e2b52ca0cd749c392e41338 211 SUPERFAMILY SSF51735 1 205 3.81E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15670 ffba46459e2b52ca0cd749c392e41338 211 Pfam PF13460 NAD(P)H-binding 7 192 9.4E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28700 58db3ca1b9eac555dce8993715b42293 200 Gene3D G3DSA:1.10.10.10 130 193 7.5E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28700 58db3ca1b9eac555dce8993715b42293 200 Gene3D G3DSA:1.10.1740.10 23 129 3.7E-19 T 09-03-2017 UA74_RS28700 58db3ca1b9eac555dce8993715b42293 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 192 5.2E-20 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28700 58db3ca1b9eac555dce8993715b42293 200 SUPERFAMILY SSF88946 22 106 4.91E-19 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28700 58db3ca1b9eac555dce8993715b42293 200 SUPERFAMILY SSF88659 113 193 7.52E-7 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28700 58db3ca1b9eac555dce8993715b42293 200 Pfam PF04542 Sigma-70 region 2 40 105 1.2E-11 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS03670 119be9c21ef5fade5f4c174cd3f6dc56 200 SUPERFAMILY SSF52980 10 144 4.45E-20 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS03670 119be9c21ef5fade5f4c174cd3f6dc56 200 Gene3D G3DSA:3.90.1570.10 10 143 7.1E-20 T 09-03-2017 IPR012296 Nuclease, putative, TT1808 UA74_RS03670 119be9c21ef5fade5f4c174cd3f6dc56 200 Pfam PF05685 Putative restriction endonuclease 20 168 7.4E-23 T 09-03-2017 IPR008538 Domain of unknown function DUF820 UA74_RS17090 155dd9600a91a666dc94572bb00286ed 573 Gene3D G3DSA:3.90.76.10 63 237 1.4E-28 T 09-03-2017 UA74_RS17090 155dd9600a91a666dc94572bb00286ed 573 Gene3D G3DSA:3.10.105.10 322 536 1.2E-38 T 09-03-2017 UA74_RS17090 155dd9600a91a666dc94572bb00286ed 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 482 2.9E-60 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS17090 155dd9600a91a666dc94572bb00286ed 573 SUPERFAMILY SSF53850 53 556 3.98E-86 T 09-03-2017 UA74_RS17090 155dd9600a91a666dc94572bb00286ed 573 PIRSF PIRSF002741 4 566 1.4E-62 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS15890 935c3ce25bfbe94ef36a90488c68ec94 316 Gene3D G3DSA:3.40.1190.20 22 303 4.9E-38 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS15890 935c3ce25bfbe94ef36a90488c68ec94 316 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 10 304 15.672 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_RS15890 935c3ce25bfbe94ef36a90488c68ec94 316 SUPERFAMILY SSF53613 23 302 3.27E-36 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS15890 935c3ce25bfbe94ef36a90488c68ec94 316 Pfam PF01256 Carbohydrate kinase 33 294 3.6E-26 T 09-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_RS07680 888c3fec0bef668457609e71e8215802 275 Pfam PF17124 ThiJ/PfpI family-like 9 174 1.9E-17 T 09-03-2017 IPR032633 ThiJ/PfpI family-like UA74_RS07680 888c3fec0bef668457609e71e8215802 275 SUPERFAMILY SSF52317 1 90 1.09E-39 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS07680 888c3fec0bef668457609e71e8215802 275 SUPERFAMILY SSF52317 120 266 1.09E-39 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS07680 888c3fec0bef668457609e71e8215802 275 Gene3D G3DSA:3.40.50.880 1 267 5.9E-54 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS17160 ce1220ff09c23f162fd63ed4a2a955ce 433 Pfam PF05977 Transmembrane secretion effector 21 422 2.3E-26 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS17160 ce1220ff09c23f162fd63ed4a2a955ce 433 Gene3D G3DSA:1.20.1250.20 234 415 5.6E-13 T 09-03-2017 UA74_RS17160 ce1220ff09c23f162fd63ed4a2a955ce 433 Gene3D G3DSA:1.20.1250.20 21 211 3.7E-16 T 09-03-2017 UA74_RS17160 ce1220ff09c23f162fd63ed4a2a955ce 433 SUPERFAMILY SSF103473 21 415 3.4E-43 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS09080 ee0d9a2540ace8687a88600726639b0f 408 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS09080 ee0d9a2540ace8687a88600726639b0f 408 Pfam PF08402 TOBE domain 307 392 5.5E-14 T 09-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 UA74_RS09080 ee0d9a2540ace8687a88600726639b0f 408 SUPERFAMILY SSF52540 24 257 5.59E-84 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09080 ee0d9a2540ace8687a88600726639b0f 408 Pfam PF00005 ABC transporter 39 181 5.6E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS09080 ee0d9a2540ace8687a88600726639b0f 408 SMART SM00382 48 239 5.2E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS09080 ee0d9a2540ace8687a88600726639b0f 408 SUPERFAMILY SSF50331 262 391 3.1E-17 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS09080 ee0d9a2540ace8687a88600726639b0f 408 Gene3D G3DSA:3.40.50.300 20 256 4.5E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20030 3e491e6ec1d0b43cd8f22e43a5f83179 306 Pfam PF00440 Bacterial regulatory proteins, tetR family 120 162 1.0E-4 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS20030 3e491e6ec1d0b43cd8f22e43a5f83179 306 Gene3D G3DSA:1.10.357.10 112 301 3.8E-18 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS20030 3e491e6ec1d0b43cd8f22e43a5f83179 306 SUPERFAMILY SSF46689 112 168 6.16E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS16120 9631052b19e348e4a27b359e5146c61f 300 Pfam PF13353 4Fe-4S single cluster domain 7 109 7.4E-7 T 09-03-2017 UA74_RS16120 9631052b19e348e4a27b359e5146c61f 300 Pfam PF04055 Radical SAM superfamily 6 148 2.0E-20 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS16120 9631052b19e348e4a27b359e5146c61f 300 SUPERFAMILY SSF102114 2 272 5.36E-50 T 09-03-2017 UA74_RS16120 9631052b19e348e4a27b359e5146c61f 300 Gene3D G3DSA:3.20.20.70 2 291 2.1E-52 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS16120 9631052b19e348e4a27b359e5146c61f 300 SMART SM00729 1 201 9.8E-8 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS28885 659ccbd3644501b078c3a22a50abade6 165 Gene3D G3DSA:1.10.1740.10 4 86 1.0E-17 T 09-03-2017 UA74_RS28885 659ccbd3644501b078c3a22a50abade6 165 Gene3D G3DSA:1.10.10.10 98 154 5.7E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28885 659ccbd3644501b078c3a22a50abade6 165 Pfam PF04542 Sigma-70 region 2 8 73 1.4E-13 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28885 659ccbd3644501b078c3a22a50abade6 165 Pfam PF08281 Sigma-70, region 4 99 140 4.6E-8 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28885 659ccbd3644501b078c3a22a50abade6 165 SUPERFAMILY SSF88946 4 82 8.63E-17 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28885 659ccbd3644501b078c3a22a50abade6 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 152 2.0E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28885 659ccbd3644501b078c3a22a50abade6 165 SUPERFAMILY SSF88659 96 153 2.8E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS12515 b1df46c0291fe151460feacd1136cd37 310 Pfam PF01040 UbiA prenyltransferase family 32 270 1.6E-64 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 UA74_RS12515 b1df46c0291fe151460feacd1136cd37 310 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 16 298 19.09 T 09-03-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 UA74_RS12515 b1df46c0291fe151460feacd1136cd37 310 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 19 296 7.3E-96 T 09-03-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 UA74_RS22230 55e2648db9307057414e93ac63e01072 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 326 2.7E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22230 55e2648db9307057414e93ac63e01072 330 Gene3D G3DSA:1.10.3720.10 93 323 2.9E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22230 55e2648db9307057414e93ac63e01072 330 SUPERFAMILY SSF161098 98 314 1.09E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS29720 fd4157eb5219fe5ca723b67db7e1529f 237 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 17 236 28.547 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 UA74_RS29720 fd4157eb5219fe5ca723b67db7e1529f 237 SUPERFAMILY SSF53335 7 235 3.93E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS29720 fd4157eb5219fe5ca723b67db7e1529f 237 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 54 235 4.3E-40 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 UA74_RS29720 fd4157eb5219fe5ca723b67db7e1529f 237 Pfam PF02390 Putative methyltransferase 59 226 9.4E-51 T 09-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 UA74_RS29720 fd4157eb5219fe5ca723b67db7e1529f 237 Gene3D G3DSA:3.40.50.150 58 192 2.3E-10 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07815 177d71297a574eff97c2a6364f960895 311 SMART SM00382 26 233 4.1E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS07815 177d71297a574eff97c2a6364f960895 311 SUPERFAMILY SSF52540 2 224 9.69E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07815 177d71297a574eff97c2a6364f960895 311 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS07815 177d71297a574eff97c2a6364f960895 311 Gene3D G3DSA:3.40.50.300 1 229 1.9E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07815 177d71297a574eff97c2a6364f960895 311 Pfam PF00005 ABC transporter 18 161 4.5E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00095 0d1466fad9c93e00f2ef48b26b5335bb 88 Pfam PF06781 Uncharacterised protein family (UPF0233) 1 88 3.3E-38 T 09-03-2017 IPR009619 Cell division protein CrgA UA74_RS00095 0d1466fad9c93e00f2ef48b26b5335bb 88 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 88 25.446 T 09-03-2017 IPR009619 Cell division protein CrgA UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 Pfam PF01595 Domain of unknown function DUF21 11 186 2.8E-35 T 09-03-2017 IPR002550 Domain of unknown function DUF21 UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 SUPERFAMILY SSF54631 189 332 2.65E-32 T 09-03-2017 UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 Gene3D G3DSA:3.30.465.10 336 425 2.8E-21 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 Pfam PF03471 Transporter associated domain 346 407 7.4E-11 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 Pfam PF00571 CBS domain 278 329 1.9E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 Pfam PF00571 CBS domain 202 257 7.8E-8 T 09-03-2017 IPR000644 CBS domain UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 Gene3D G3DSA:3.10.580.10 188 335 6.0E-20 T 09-03-2017 UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 SMART SM00116 281 329 15.0 T 09-03-2017 IPR000644 CBS domain UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 SMART SM00116 211 260 4.7E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 SMART SM01091 345 427 7.1E-19 T 09-03-2017 IPR005170 Transporter-associated domain UA74_RS24590 4c4d734cf9fa8c99b6b0192246596fc6 452 SUPERFAMILY SSF56176 340 413 1.94E-12 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS16125 58e16cc80007ab3992bb0afecbbdbead 132 Gene3D G3DSA:3.40.50.1580 58 124 0.001 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS16125 58e16cc80007ab3992bb0afecbbdbead 132 SUPERFAMILY SSF53167 3 98 1.44E-7 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 SMART SM00359 281 360 3.3E-16 T 09-03-2017 IPR002478 PUA domain GO:0003723 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 SUPERFAMILY SSF53633 12 259 6.15E-55 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 Gene3D G3DSA:2.30.130.10 279 366 7.3E-21 T 09-03-2017 IPR015947 PUA-like domain UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 8.3E-51 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 8.3E-51 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 8.3E-51 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 8.3E-51 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 8.3E-51 T 09-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 Pfam PF01472 PUA domain 281 351 6.9E-18 T 09-03-2017 IPR002478 PUA domain GO:0003723 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 366 1.4E-118 T 09-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 09-03-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 SUPERFAMILY SSF88697 281 367 1.77E-16 T 09-03-2017 IPR015947 PUA-like domain UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 PIRSF PIRSF000729 8 369 2.2E-113 T 09-03-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 Pfam PF00696 Amino acid kinase family 13 240 2.1E-35 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 Gene3D G3DSA:3.40.1160.10 12 259 3.2E-48 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS08320 578a799f70424e8a55917880ea26e53a 369 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 262 33.884 T 09-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_RS21370 3d665ac76f2d120a567ed90e9763af57 361 Pfam PF04018 Domain of unknown function (DUF368) 44 292 1.7E-65 T 09-03-2017 IPR007163 Protein of unknown function DUF368 UA74_RS00860 8d6a92ed8875ed1f88d7d692ea656736 544 SUPERFAMILY SSF51679 7 289 2.52E-55 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS00860 8d6a92ed8875ed1f88d7d692ea656736 544 Pfam PF01814 Hemerythrin HHE cation binding domain 391 535 5.8E-17 T 09-03-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 UA74_RS00860 8d6a92ed8875ed1f88d7d692ea656736 544 Gene3D G3DSA:1.20.120.520 384 540 7.1E-27 T 09-03-2017 UA74_RS00860 8d6a92ed8875ed1f88d7d692ea656736 544 Gene3D G3DSA:3.20.20.30 8 288 7.7E-61 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS00860 8d6a92ed8875ed1f88d7d692ea656736 544 Pfam PF00296 Luciferase-like monooxygenase 19 230 2.1E-45 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS15200 e54cf7f27f657848e5d2945fbb775fcb 211 Pfam PF13302 Acetyltransferase (GNAT) domain 13 146 9.5E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS15200 e54cf7f27f657848e5d2945fbb775fcb 211 Gene3D G3DSA:3.40.630.30 12 174 1.1E-21 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15200 e54cf7f27f657848e5d2945fbb775fcb 211 SUPERFAMILY SSF55729 8 170 5.01E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS10975 e3e8d2ab533c30a24c76a743416e994c 151 Pfam PF08592 Domain of unknown function (DUF1772) 19 147 7.8E-16 T 09-03-2017 IPR013901 Protein of unknown function DUF1772 UA74_RS15735 fdaa326949d1263c9105ae7b1920ab9a 711 Pfam PF01580 FtsK/SpoIIIE family 348 513 1.2E-6 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_RS15735 fdaa326949d1263c9105ae7b1920ab9a 711 SUPERFAMILY SSF52540 283 541 7.26E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15735 fdaa326949d1263c9105ae7b1920ab9a 711 Gene3D G3DSA:3.40.50.300 298 520 3.7E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06530 bcdb978f995c5d35042f5890e2411031 260 SUPERFAMILY SSF52402 1 254 3.21E-74 T 09-03-2017 UA74_RS06530 bcdb978f995c5d35042f5890e2411031 260 PIRSF PIRSF000090 1 260 3.4E-84 T 09-03-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 UA74_RS06530 bcdb978f995c5d35042f5890e2411031 260 SMART SM00893 23 213 6.6E-54 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_RS06530 bcdb978f995c5d35042f5890e2411031 260 Gene3D G3DSA:3.40.50.620 1 259 2.2E-90 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS06530 bcdb978f995c5d35042f5890e2411031 260 Pfam PF01012 Electron transfer flavoprotein domain 25 208 5.0E-46 T 09-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_RS14040 f95ea114f9301e893312e96a1aae9512 275 SUPERFAMILY SSF63992 1 267 3.92E-83 T 09-03-2017 IPR007035 Peptidase M55, D-aminopeptidase UA74_RS14040 f95ea114f9301e893312e96a1aae9512 275 Gene3D G3DSA:3.30.1360.130 213 268 4.5E-12 T 09-03-2017 UA74_RS14040 f95ea114f9301e893312e96a1aae9512 275 Pfam PF04951 D-aminopeptidase 1 260 2.4E-92 T 09-03-2017 IPR007035 Peptidase M55, D-aminopeptidase UA74_RS14040 f95ea114f9301e893312e96a1aae9512 275 Gene3D G3DSA:3.40.50.10780 1 208 1.9E-74 T 09-03-2017 IPR027476 D-aminopeptidase, N-terminal UA74_RS14040 f95ea114f9301e893312e96a1aae9512 275 PIRSF PIRSF015853 1 272 3.9E-91 T 09-03-2017 IPR007035 Peptidase M55, D-aminopeptidase UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 PRINTS PR00421 Thioredoxin family signature 29 38 2.4E-8 T 09-03-2017 UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 PRINTS PR00421 Thioredoxin family signature 21 29 2.4E-8 T 09-03-2017 UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 PRINTS PR00421 Thioredoxin family signature 68 79 2.4E-8 T 09-03-2017 UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 Pfam PF00085 Thioredoxin 4 102 7.8E-25 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 SUPERFAMILY SSF52833 3 103 9.93E-32 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.2E-29 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 PIRSF PIRSF000077 1 104 4.8E-27 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_RS19035 f738d3fc234eec52a24c3dc804ff6afe 113 Gene3D G3DSA:3.40.30.10 4 101 4.1E-31 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 SUPERFAMILY SSF51735 14 242 4.0E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 Gene3D G3DSA:3.40.50.720 15 239 3.8E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 Pfam PF00106 short chain dehydrogenase 16 192 1.4E-42 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-18 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.7E-18 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.7E-18 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.7E-18 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS02185 2ffd4a0a5a6794ef0e93ea86a9d076db 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.7E-18 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08655 4a22ecb0848bc0b0ee78dac3dd10528d 626 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 164 174 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS08655 4a22ecb0848bc0b0ee78dac3dd10528d 626 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 12 612 5.8E-283 T 09-03-2017 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 UA74_RS08655 4a22ecb0848bc0b0ee78dac3dd10528d 626 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS08655 4a22ecb0848bc0b0ee78dac3dd10528d 626 SUPERFAMILY SSF143975 11 428 1.7E-143 T 09-03-2017 UA74_RS08655 4a22ecb0848bc0b0ee78dac3dd10528d 626 SUPERFAMILY SSF52016 429 612 9.42E-57 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS08655 4a22ecb0848bc0b0ee78dac3dd10528d 626 Pfam PF00920 Dehydratase family 75 609 1.8E-162 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS16735 cb6a36f06f9ab97bbbc79ade6873bcea 331 SUPERFAMILY SSF53807 55 329 1.3E-44 T 09-03-2017 UA74_RS16735 cb6a36f06f9ab97bbbc79ade6873bcea 331 Pfam PF01497 Periplasmic binding protein 64 301 3.8E-31 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS16735 cb6a36f06f9ab97bbbc79ade6873bcea 331 Gene3D G3DSA:3.40.50.1980 60 183 1.8E-17 T 09-03-2017 UA74_RS16735 cb6a36f06f9ab97bbbc79ade6873bcea 331 Gene3D G3DSA:3.40.50.1980 184 328 2.6E-22 T 09-03-2017 UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 SUPERFAMILY SSF51735 4 184 4.87E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 179 6.4E-75 T 09-03-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 Gene3D G3DSA:3.50.50.60 9 38 9.3E-4 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 Gene3D G3DSA:1.10.1040.10 39 326 2.8E-109 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 1.8E-62 T 09-03-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 1.5E-131 T 09-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 SUPERFAMILY SSF48179 185 330 3.74E-66 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS26125 d1e225ed88b43b7ae3884a138cca7607 337 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 3 330 44.89 T 09-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_RS01825 a5f5d0e6da224ad3554d47bd3bcb09d2 358 SUPERFAMILY SSF101478 2 341 2.62E-46 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 UA74_RS01825 a5f5d0e6da224ad3554d47bd3bcb09d2 358 Pfam PF03747 ADP-ribosylglycohydrolase 7 322 1.8E-54 T 09-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 UA74_RS27430 895b644f6e688286eb32524cf2d57e04 328 SUPERFAMILY SSF51430 11 308 3.8E-98 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS27430 895b644f6e688286eb32524cf2d57e04 328 Pfam PF00248 Aldo/keto reductase family 18 307 3.1E-74 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS27430 895b644f6e688286eb32524cf2d57e04 328 Gene3D G3DSA:3.20.20.100 7 320 2.6E-114 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS12630 15aec3e6c9f87a076ad6e99b994bb2be 436 Pfam PF00266 Aminotransferase class-V 31 411 6.3E-135 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS12630 15aec3e6c9f87a076ad6e99b994bb2be 436 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 423 8.1E-172 T 09-03-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 UA74_RS12630 15aec3e6c9f87a076ad6e99b994bb2be 436 Gene3D G3DSA:3.90.1150.10 299 417 3.5E-25 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS12630 15aec3e6c9f87a076ad6e99b994bb2be 436 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 232 251 - T 09-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UA74_RS12630 15aec3e6c9f87a076ad6e99b994bb2be 436 Gene3D G3DSA:3.40.640.10 42 298 4.4E-85 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS12630 15aec3e6c9f87a076ad6e99b994bb2be 436 SUPERFAMILY SSF53383 9 419 4.76E-117 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 308 874 3.6E-168 T 09-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 1 277 8.5E-127 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 SUPERFAMILY SSF109604 655 806 1.57E-7 T 09-03-2017 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 284 5.8E-121 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 53 68 3.1E-57 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 154 169 3.1E-57 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 239 255 3.1E-57 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 105 129 3.1E-57 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 74 94 3.1E-57 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 131 151 3.1E-57 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 SUPERFAMILY SSF55681 2 278 2.98E-109 T 09-03-2017 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 Gene3D G3DSA:3.30.930.10 1 199 8.3E-86 T 09-03-2017 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 279 49.921 T 09-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 Gene3D G3DSA:1.20.58.180 203 284 2.2E-27 T 09-03-2017 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 305 1006 20.326 T 09-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS19070 03945843eff1c948d114e54e1de8891b 1013 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 307 1004 6.3E-152 T 09-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_RS08280 75f69e5d7d646a3e4243578bed329f13 951 Pfam PF00575 S1 RNA binding domain 366 443 7.9E-5 T 09-03-2017 IPR003029 S1 domain GO:0003676 UA74_RS08280 75f69e5d7d646a3e4243578bed329f13 951 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 25 74 1.0E-9 T 09-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal UA74_RS08280 75f69e5d7d646a3e4243578bed329f13 951 Pfam PF10150 Ribonuclease E/G family 446 717 2.2E-101 T 09-03-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 UA74_RS08280 75f69e5d7d646a3e4243578bed329f13 951 SUPERFAMILY SSF50249 367 450 6.2E-17 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS08280 75f69e5d7d646a3e4243578bed329f13 951 Gene3D G3DSA:2.40.50.140 364 450 2.7E-29 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS08280 75f69e5d7d646a3e4243578bed329f13 951 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 342 744 3.4E-150 T 09-03-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 UA74_RS08280 75f69e5d7d646a3e4243578bed329f13 951 SMART SM00316 365 444 1.6E-7 T 09-03-2017 IPR022967 RNA-binding domain, S1 UA74_RS11615 2e1781bbc000c28a187407c8292dcf14 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 2.9E-68 T 09-03-2017 UA74_RS11615 2e1781bbc000c28a187407c8292dcf14 255 SUPERFAMILY SSF51735 6 253 1.02E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11615 2e1781bbc000c28a187407c8292dcf14 255 PIRSF PIRSF000094 2 255 7.2E-88 T 09-03-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 UA74_RS11615 2e1781bbc000c28a187407c8292dcf14 255 Gene3D G3DSA:3.40.50.720 4 252 1.9E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30275 ee2dd62966ce707046a78224c6026ae7 398 SMART SM00267 220 398 1.5E-45 T 09-03-2017 IPR000160 GGDEF domain UA74_RS30275 ee2dd62966ce707046a78224c6026ae7 398 Pfam PF00990 Diguanylate cyclase, GGDEF domain 231 393 4.1E-41 T 09-03-2017 IPR000160 GGDEF domain UA74_RS30275 ee2dd62966ce707046a78224c6026ae7 398 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 229 397 1.7E-44 T 09-03-2017 IPR000160 GGDEF domain UA74_RS30275 ee2dd62966ce707046a78224c6026ae7 398 SUPERFAMILY SSF55073 237 396 4.32E-41 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS30275 ee2dd62966ce707046a78224c6026ae7 398 Gene3D G3DSA:3.30.70.270 233 397 8.7E-47 T 09-03-2017 UA74_RS05940 4b56c57c2afe21f2d82f03fc9e9e9e91 175 Gene3D G3DSA:3.40.50.720 20 73 4.2E-7 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05940 4b56c57c2afe21f2d82f03fc9e9e9e91 175 SUPERFAMILY SSF51735 17 128 1.41E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08025 ed0aea1a35c5f48a68700467da07a773 179 SMART SM00507 83 132 9.2E-15 T 09-03-2017 IPR003615 HNH nuclease UA74_RS08025 ed0aea1a35c5f48a68700467da07a773 179 Pfam PF14279 HNH endonuclease 96 142 4.9E-13 T 09-03-2017 IPR029471 HNH endonuclease 5 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 Pfam PF00083 Sugar (and other) transporter 31 462 2.1E-121 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 SUPERFAMILY SSF103473 21 460 1.31E-84 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 25 459 2.3E-121 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 Gene3D G3DSA:1.20.1250.20 270 458 6.7E-24 T 09-03-2017 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 Gene3D G3DSA:1.20.1250.20 29 212 4.0E-28 T 09-03-2017 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 279 289 3.0E-27 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 37 47 3.0E-27 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 364 385 3.0E-27 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 120 139 3.0E-27 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 387 399 3.0E-27 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS22940 5bbe89d92fe6246983f991b7823a79db 477 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 100 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 Gene3D G3DSA:3.30.160.20 209 286 5.2E-33 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 Pfam PF00472 RF-1 domain 210 319 4.8E-39 T 09-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 2 355 36.29 T 09-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 SUPERFAMILY SSF75620 12 351 5.49E-120 T 09-03-2017 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 Gene3D G3DSA:1.20.58.410 6 82 3.3E-12 T 09-03-2017 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 353 1.5E-143 T 09-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 Pfam PF03462 PCRF domain 12 202 7.0E-62 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 UA74_RS07105 e91e216c26c6a49d651b486e50498cba 358 SMART SM00937 64 177 2.9E-52 T 09-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 UA74_RS26200 492e714f4517d432eb5ef95e4f47de2b 400 SUPERFAMILY SSF63829 350 398 2.09E-12 T 09-03-2017 UA74_RS26200 492e714f4517d432eb5ef95e4f47de2b 400 SUPERFAMILY SSF63829 89 307 2.09E-12 T 09-03-2017 UA74_RS26200 492e714f4517d432eb5ef95e4f47de2b 400 Gene3D G3DSA:2.120.10.30 80 311 8.2E-33 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS26200 492e714f4517d432eb5ef95e4f47de2b 400 Pfam PF07995 Glucose / Sorbosone dehydrogenase 101 297 1.2E-19 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 UA74_RS15570 fcc2ad63299cd8a0713b157dade04d52 251 SUPERFAMILY SSF52799 5 239 1.09E-44 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like UA74_RS15570 fcc2ad63299cd8a0713b157dade04d52 251 Gene3D G3DSA:3.90.190.10 8 171 4.7E-23 T 09-03-2017 IPR029021 Protein-tyrosine phosphatase-like UA74_RS15570 fcc2ad63299cd8a0713b157dade04d52 251 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 137 147 - T 09-03-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 UA74_RS15570 fcc2ad63299cd8a0713b157dade04d52 251 Pfam PF13350 Tyrosine phosphatase family 6 242 9.4E-59 T 09-03-2017 IPR026893 Tyrosine/serine-protein phosphatase IphP-type UA74_RS21250 598218de20d0ccfa24851059690a20eb 281 SUPERFAMILY SSF46689 16 101 1.2E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS21250 598218de20d0ccfa24851059690a20eb 281 SUPERFAMILY SSF48498 98 211 5.48E-13 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS21250 598218de20d0ccfa24851059690a20eb 281 Gene3D G3DSA:1.10.10.60 16 71 1.0E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS21250 598218de20d0ccfa24851059690a20eb 281 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.3E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS21250 598218de20d0ccfa24851059690a20eb 281 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.3E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS21250 598218de20d0ccfa24851059690a20eb 281 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 2.3E-17 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS21250 598218de20d0ccfa24851059690a20eb 281 Gene3D G3DSA:1.10.357.10 72 213 8.1E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 Gene3D G3DSA:1.10.10.10 4 72 8.3E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 SUPERFAMILY SSF46785 5 70 7.26E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 SUPERFAMILY SSF48008 89 222 3.4E-22 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 SMART SM00345 7 66 1.2E-18 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 3.9E-17 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 Pfam PF07729 FCD domain 93 214 2.2E-21 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 SMART SM00895 93 215 2.1E-17 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 6.0E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 6.0E-5 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS01850 51ce7660f9d1ccb1138bf580e8b9acfb 226 Gene3D G3DSA:1.20.120.530 88 221 3.8E-24 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS00345 68d4ad37a6d3427bf7c146afb15e8871 1245 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 434 444 - T 09-03-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_RS00345 68d4ad37a6d3427bf7c146afb15e8871 1245 Gene3D G3DSA:3.40.50.200 188 493 1.0E-86 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS00345 68d4ad37a6d3427bf7c146afb15e8871 1245 SUPERFAMILY SSF52743 201 492 1.26E-82 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS00345 68d4ad37a6d3427bf7c146afb15e8871 1245 Pfam PF00082 Subtilase family 220 483 9.7E-54 T 09-03-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_RS00345 68d4ad37a6d3427bf7c146afb15e8871 1245 PRINTS PR00723 Subtilisin serine protease family (S8) signature 433 449 8.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS00345 68d4ad37a6d3427bf7c146afb15e8871 1245 PRINTS PR00723 Subtilisin serine protease family (S8) signature 220 239 8.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS00345 68d4ad37a6d3427bf7c146afb15e8871 1245 PRINTS PR00723 Subtilisin serine protease family (S8) signature 258 271 8.8E-20 T 09-03-2017 IPR015500 Peptidase S8, subtilisin-related UA74_RS26555 ecb56151f14d13e6f63d659ed30bce1d 295 Gene3D G3DSA:3.40.190.10 32 140 1.1E-35 T 09-03-2017 UA74_RS26555 ecb56151f14d13e6f63d659ed30bce1d 295 Gene3D G3DSA:3.40.190.10 248 292 1.1E-35 T 09-03-2017 UA74_RS26555 ecb56151f14d13e6f63d659ed30bce1d 295 SUPERFAMILY SSF53850 36 293 2.99E-39 T 09-03-2017 UA74_RS26555 ecb56151f14d13e6f63d659ed30bce1d 295 Gene3D G3DSA:3.40.190.120 141 237 1.0E-18 T 09-03-2017 UA74_RS26555 ecb56151f14d13e6f63d659ed30bce1d 295 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 36 293 5.0E-37 T 09-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 UA74_RS00705 b511e9e10779ea97658a53cae70814bb 399 Gene3D G3DSA:3.40.640.10 31 259 9.1E-44 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS00705 b511e9e10779ea97658a53cae70814bb 399 Gene3D G3DSA:3.90.1150.10 260 398 5.2E-19 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS00705 b511e9e10779ea97658a53cae70814bb 399 SUPERFAMILY SSF53383 3 398 6.19E-66 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS00705 b511e9e10779ea97658a53cae70814bb 399 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 6.8E-123 T 09-03-2017 IPR011340 Cysteine desulfurase-related UA74_RS00705 b511e9e10779ea97658a53cae70814bb 399 Pfam PF00266 Aminotransferase class-V 295 391 1.3E-7 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS00705 b511e9e10779ea97658a53cae70814bb 399 Pfam PF00266 Aminotransferase class-V 21 234 2.1E-31 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 Pfam PF13541 Subunit ChlI of Mg-chelatase 373 432 4.7E-7 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 Gene3D G3DSA:3.40.50.300 74 279 6.7E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 326 349 1.2E-83 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 217 245 1.2E-83 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 178 202 1.2E-83 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 85 113 1.2E-83 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 128 145 1.2E-83 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 16 40 1.2E-83 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 252 278 1.2E-83 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 SUPERFAMILY SSF54211 298 454 2.66E-30 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 SMART SM00382 93 248 8.8E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 TIGRFAM TIGR00416 sms: DNA repair protein RadA 10 433 3.0E-152 T 09-03-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 Gene3D G3DSA:3.30.230.10 289 433 2.8E-27 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 Pfam PF13481 AAA domain 62 226 7.5E-17 T 09-03-2017 UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 SUPERFAMILY SSF52540 75 293 1.61E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01630 8a771211ee3141cd2776bb8d84c03e71 460 Hamap MF_01498 DNA repair protein RadA [radA]. 27 457 42.352 T 09-03-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 UA74_RS07055 d4159089952cfac3c59f0653acc1d4c1 215 Gene3D G3DSA:1.20.1260.10 35 206 1.1E-56 T 09-03-2017 IPR012347 Ferritin-related UA74_RS07055 d4159089952cfac3c59f0653acc1d4c1 215 Pfam PF03713 Domain of unknown function (DUF305) 41 203 1.9E-46 T 09-03-2017 IPR005183 Domain of unknown function DUF305 UA74_RS20565 e806315451b38159f69b7abf5448f178 141 Gene3D G3DSA:3.30.1330.40 7 137 3.5E-39 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS20565 e806315451b38159f69b7abf5448f178 141 Pfam PF01042 Endoribonuclease L-PSP 26 134 3.0E-21 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family UA74_RS20565 e806315451b38159f69b7abf5448f178 141 SUPERFAMILY SSF55298 25 136 1.37E-30 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS24795 15e3aa6e50370e84b10de447c983247a 371 SUPERFAMILY SSF48576 27 370 3.84E-72 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS24795 15e3aa6e50370e84b10de447c983247a 371 Gene3D G3DSA:1.10.600.10 29 370 2.2E-78 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS24795 15e3aa6e50370e84b10de447c983247a 371 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 101 115 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS24795 15e3aa6e50370e84b10de447c983247a 371 Pfam PF00348 Polyprenyl synthetase 52 308 7.0E-44 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS22435 53a5b5217d85199513c511beadb2b349 233 SUPERFAMILY SSF48498 86 192 2.83E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS22435 53a5b5217d85199513c511beadb2b349 233 SUPERFAMILY SSF46689 7 89 1.5E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22435 53a5b5217d85199513c511beadb2b349 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 5.6E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22435 53a5b5217d85199513c511beadb2b349 233 Gene3D G3DSA:1.10.357.10 6 216 2.5E-30 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS24680 3eb918ff86586e478eb034f768f0e1ef 267 SUPERFAMILY SSF52096 3 254 2.49E-66 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS24680 3eb918ff86586e478eb034f768f0e1ef 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 253 3.9E-48 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 UA74_RS24680 3eb918ff86586e478eb034f768f0e1ef 267 Gene3D G3DSA:3.90.226.10 3 253 5.4E-64 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS16395 67c4212418be822ab44947d52838a214 1628 Gene3D G3DSA:3.40.1140.10 34 106 5.5E-18 T 09-03-2017 UA74_RS16395 67c4212418be822ab44947d52838a214 1628 Gene3D G3DSA:3.40.1140.10 1502 1586 5.5E-18 T 09-03-2017 UA74_RS16395 67c4212418be822ab44947d52838a214 1628 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1471 1567 2.0E-17 T 09-03-2017 UA74_RS16395 67c4212418be822ab44947d52838a214 1628 SUPERFAMILY SSF52540 1475 1590 5.84E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16395 67c4212418be822ab44947d52838a214 1628 SUPERFAMILY SSF52540 34 109 5.84E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12575 3d6b309de66c8e688b529c3c988a6363 295 SUPERFAMILY SSF56059 118 269 3.06E-10 T 09-03-2017 UA74_RS26140 e99016deaf0074a9e7f289fd00906014 225 Pfam PF10756 Bacterial PH domain 61 131 3.7E-12 T 09-03-2017 IPR019692 Protein of unknown function DUF2581 UA74_RS26140 e99016deaf0074a9e7f289fd00906014 225 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 38 131 8.0E-10 T 09-03-2017 IPR020535 Low molecular weight antigen Cfp6 UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 354 370 1.3E-18 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 115 134 1.3E-18 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 39 56 1.3E-18 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 169 184 1.3E-18 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 60 78 1.3E-18 T 09-03-2017 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 SUPERFAMILY SSF51445 29 380 1.24E-58 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 Gene3D G3DSA:3.20.20.80 27 389 4.1E-71 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS22355 8b371ecbfad265f9522c99850ed5ddb3 795 Pfam PF01301 Glycosyl hydrolases family 35 39 381 4.0E-46 T 09-03-2017 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS15095 12850abd79524eda784c4712acebb263 178 SUPERFAMILY SSF55729 9 156 3.87E-28 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15095 12850abd79524eda784c4712acebb263 178 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 2.6E-22 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS15095 12850abd79524eda784c4712acebb263 178 Gene3D G3DSA:3.40.630.30 7 164 4.3E-35 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29955 5bace9aa1f2a0029ba07a02558be969b 205 SUPERFAMILY SSF56784 1 190 2.56E-43 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29955 5bace9aa1f2a0029ba07a02558be969b 205 Gene3D G3DSA:3.40.50.1000 58 194 2.4E-40 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29955 5bace9aa1f2a0029ba07a02558be969b 205 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 1 163 6.0E-7 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS29955 5bace9aa1f2a0029ba07a02558be969b 205 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 1 169 3.3E-19 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS29955 5bace9aa1f2a0029ba07a02558be969b 205 Gene3D G3DSA:1.10.150.240 12 57 6.7E-9 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 UA74_RS29955 5bace9aa1f2a0029ba07a02558be969b 205 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 169 1.6E-24 T 09-03-2017 IPR023214 HAD-like domain UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 Gene3D G3DSA:3.30.160.20 36 95 3.1E-29 T 09-03-2017 IPR014720 Double-stranded RNA-binding domain UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 1.0E-27 T 09-03-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 4.1E-28 T 09-03-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 09-03-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 35 186 3.3E-67 T 09-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 SUPERFAMILY SSF54768 34 99 2.83E-22 T 09-03-2017 UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 Gene3D G3DSA:3.30.230.10 101 181 4.3E-31 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 SUPERFAMILY SSF54211 102 181 5.56E-24 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS03015 3791e9b816d962446f217ff1d73d4264 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 4 186 33.888 T 09-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_RS16335 c39d339942db8048dc1bbfae2db45b26 276 Pfam PF01555 DNA methylase 15 79 2.8E-13 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 UA74_RS16335 c39d339942db8048dc1bbfae2db45b26 276 Gene3D G3DSA:3.40.50.150 14 84 2.0E-17 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16335 c39d339942db8048dc1bbfae2db45b26 276 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 41 59 1.1E-7 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UA74_RS16335 c39d339942db8048dc1bbfae2db45b26 276 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 64 84 1.1E-7 T 09-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UA74_RS16335 c39d339942db8048dc1bbfae2db45b26 276 SUPERFAMILY SSF53335 21 190 1.95E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16335 c39d339942db8048dc1bbfae2db45b26 276 Gene3D G3DSA:3.40.50.150 97 224 7.4E-12 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15495 84f80664fa108d45a8d0a156cf08c8fb 352 SUPERFAMILY SSF51735 316 349 1.6E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15495 84f80664fa108d45a8d0a156cf08c8fb 352 SUPERFAMILY SSF51735 6 265 1.6E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15495 84f80664fa108d45a8d0a156cf08c8fb 352 Gene3D G3DSA:3.40.50.720 4 262 3.4E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15495 84f80664fa108d45a8d0a156cf08c8fb 352 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 103 2.3E-8 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS04790 888828035f2427208039a3a4dec3efdb 278 SUPERFAMILY SSF69618 9 271 3.27E-52 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS04790 888828035f2427208039a3a4dec3efdb 278 Gene3D G3DSA:3.40.50.10090 137 273 5.5E-35 T 09-03-2017 UA74_RS04790 888828035f2427208039a3a4dec3efdb 278 Gene3D G3DSA:3.40.50.10090 5 135 1.7E-26 T 09-03-2017 UA74_RS04790 888828035f2427208039a3a4dec3efdb 278 Pfam PF02602 Uroporphyrinogen-III synthase HemD 22 262 4.7E-36 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 Pfam PF01168 Alanine racemase, N-terminal domain 27 241 5.7E-51 T 09-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 SUPERFAMILY SSF51419 27 245 9.35E-45 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 Pfam PF00842 Alanine racemase, C-terminal domain 252 375 5.3E-33 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 SMART SM01005 250 377 1.2E-49 T 09-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 45 55 - T 09-03-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 283 298 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 304 321 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 76 94 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 214 241 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 359 372 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 266 281 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 40 56 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 171 182 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 134 146 1.2E-48 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 Gene3D G3DSA:3.20.20.10 27 234 6.8E-54 T 09-03-2017 IPR029066 PLP-binding barrel UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 Gene3D G3DSA:2.40.37.10 235 375 1.9E-44 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 Hamap MF_01201 Alanine racemase. 16 377 25.99 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 SUPERFAMILY SSF50621 247 375 8.37E-38 T 09-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_RS19315 491e3b8a6314306d4829617d7cb046a5 377 TIGRFAM TIGR00492 alr: alanine racemase 27 374 2.8E-68 T 09-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_RS13185 57184ad8c7dc875824beb8ffd7e41c6f 427 Gene3D G3DSA:3.40.50.2000 2 263 4.0E-16 T 09-03-2017 UA74_RS13185 57184ad8c7dc875824beb8ffd7e41c6f 427 SUPERFAMILY SSF53756 1 423 4.0E-69 T 09-03-2017 UA74_RS13185 57184ad8c7dc875824beb8ffd7e41c6f 427 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 223 404 1.9E-11 T 09-03-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 UA74_RS13185 57184ad8c7dc875824beb8ffd7e41c6f 427 Gene3D G3DSA:3.40.50.2000 264 406 1.9E-22 T 09-03-2017 UA74_RS13185 57184ad8c7dc875824beb8ffd7e41c6f 427 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 9 408 1.7E-35 T 09-03-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_RS00235 6d3009f45470048559647d33c886eaa0 524 ProSitePatterns PS01303 BCCT family of transporters signature. 309 318 - T 09-03-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 UA74_RS00235 6d3009f45470048559647d33c886eaa0 524 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 40 493 1.7E-160 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 UA74_RS00235 6d3009f45470048559647d33c886eaa0 524 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 492 2.2E-177 T 09-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 UA74_RS26015 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 Pfam PF01983 Guanylyl transferase CofC like 7 207 1.7E-8 T 09-03-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 UA74_RS26015 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 SUPERFAMILY SSF53448 17 209 6.19E-24 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS26015 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 7 205 1.7E-40 T 09-03-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 UA74_RS26015 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 5 212 21.387 T 09-03-2017 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 UA74_RS26015 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 Gene3D G3DSA:3.90.550.10 8 178 3.1E-19 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS11730 5a31a11cf5e7b4e7423ba16095cd7937 326 Gene3D G3DSA:3.40.190.10 173 273 3.5E-19 T 09-03-2017 UA74_RS11730 5a31a11cf5e7b4e7423ba16095cd7937 326 Gene3D G3DSA:3.40.190.10 274 310 4.0E-26 T 09-03-2017 UA74_RS11730 5a31a11cf5e7b4e7423ba16095cd7937 326 Gene3D G3DSA:3.40.190.10 89 172 4.0E-26 T 09-03-2017 UA74_RS11730 5a31a11cf5e7b4e7423ba16095cd7937 326 SMART SM00062 91 313 2.3E-53 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS11730 5a31a11cf5e7b4e7423ba16095cd7937 326 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 92 311 9.9E-46 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS11730 5a31a11cf5e7b4e7423ba16095cd7937 326 SUPERFAMILY SSF53850 81 311 2.63E-51 T 09-03-2017 UA74_RS04240 8ce99cfed19f5aafa6bddeb82bf5cd19 287 Gene3D G3DSA:3.40.50.150 11 184 5.3E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04240 8ce99cfed19f5aafa6bddeb82bf5cd19 287 SUPERFAMILY SSF53335 16 256 3.55E-42 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04240 8ce99cfed19f5aafa6bddeb82bf5cd19 287 SMART SM00650 24 185 1.8E-61 T 09-03-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 UA74_RS04240 8ce99cfed19f5aafa6bddeb82bf5cd19 287 Pfam PF00398 Ribosomal RNA adenine dimethylase 10 253 1.0E-31 T 09-03-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm UA74_RS04240 8ce99cfed19f5aafa6bddeb82bf5cd19 287 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 40 67 - T 09-03-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00385 P450 superfamily signature 246 263 2.1E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00385 P450 superfamily signature 281 292 2.1E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00385 P450 superfamily signature 359 370 2.1E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00385 P450 superfamily signature 350 359 2.1E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00359 B-class P450 signature 145 161 5.8E-29 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00359 B-class P450 signature 199 221 5.8E-29 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00359 B-class P450 signature 350 359 5.8E-29 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00359 B-class P450 signature 162 177 5.8E-29 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00359 B-class P450 signature 299 326 5.8E-29 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00359 B-class P450 signature 281 292 5.8E-29 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 PRINTS PR00359 B-class P450 signature 359 370 5.8E-29 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 SUPERFAMILY SSF48264 18 413 3.93E-88 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 Pfam PF00067 Cytochrome P450 203 268 2.7E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 Pfam PF00067 Cytochrome P450 281 380 6.8E-13 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16075 d8608f8d578e898251ec446427860b74 419 Gene3D G3DSA:1.10.630.10 16 415 4.3E-112 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS04825 de99de55d01f30d1fcc1c61acd52d740 358 SUPERFAMILY SSF51735 142 286 3.59E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS04825 de99de55d01f30d1fcc1c61acd52d740 358 Gene3D G3DSA:3.40.50.720 138 276 6.7E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS04825 de99de55d01f30d1fcc1c61acd52d740 358 Gene3D G3DSA:1.10.287.70 42 134 4.4E-14 T 09-03-2017 UA74_RS04825 de99de55d01f30d1fcc1c61acd52d740 358 Pfam PF02254 TrkA-N domain 146 263 6.5E-26 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_RS04825 de99de55d01f30d1fcc1c61acd52d740 358 SUPERFAMILY SSF81324 42 163 1.44E-19 T 09-03-2017 UA74_RS04825 de99de55d01f30d1fcc1c61acd52d740 358 Pfam PF07885 Ion channel 46 126 1.0E-12 T 09-03-2017 IPR013099 Potassium channel domain UA74_RS00505 7d202de4023d62635bd3239f4c338482 266 Pfam PF02517 CAAX protease self-immunity 162 249 1.9E-14 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 UA74_RS10400 0346fe8e0d8d41d55e2de3741e7a9ca6 393 Gene3D G3DSA:3.90.1150.10 283 389 2.3E-22 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS10400 0346fe8e0d8d41d55e2de3741e7a9ca6 393 SUPERFAMILY SSF53383 29 389 3.89E-78 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS10400 0346fe8e0d8d41d55e2de3741e7a9ca6 393 Gene3D G3DSA:3.40.640.10 54 282 4.3E-45 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS10400 0346fe8e0d8d41d55e2de3741e7a9ca6 393 Pfam PF00266 Aminotransferase class-V 55 376 2.4E-32 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS10400 0346fe8e0d8d41d55e2de3741e7a9ca6 393 PIRSF PIRSF000524 20 393 1.1E-72 T 09-03-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 322 53.954 T 09-03-2017 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 PIRSF PIRSF018005 3 323 2.0E-120 T 09-03-2017 IPR017804 Methyltransferase EgtD-like UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 20 319 4.2E-108 T 09-03-2017 IPR017804 Methyltransferase EgtD-like UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 SUPERFAMILY SSF53335 73 207 5.14E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 SUPERFAMILY SSF53335 257 315 5.14E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 Gene3D G3DSA:3.40.50.150 244 246 9.3E-6 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 Gene3D G3DSA:3.40.50.150 54 200 9.3E-6 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 Gene3D G3DSA:3.40.50.150 286 309 9.3E-6 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS11530 fdd61e1bb65ff473659cf72ce601d595 323 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 193 317 1.0E-40 T 09-03-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent UA74_RS01970 5dc7cd0b979e63a673a5a7c4c99c2717 507 Gene3D G3DSA:3.20.20.300 20 338 2.0E-87 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01970 5dc7cd0b979e63a673a5a7c4c99c2717 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 2.6E-5 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01970 5dc7cd0b979e63a673a5a7c4c99c2717 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 88 107 2.6E-5 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01970 5dc7cd0b979e63a673a5a7c4c99c2717 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 241 259 2.6E-5 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01970 5dc7cd0b979e63a673a5a7c4c99c2717 507 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 34 337 7.3E-71 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01970 5dc7cd0b979e63a673a5a7c4c99c2717 507 SUPERFAMILY SSF51445 13 337 5.26E-74 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS29715 85b0cf44e9c3572efcf04b2f099d3d6e 305 Pfam PF02898 Nitric oxide synthase, oxygenase domain 2 290 4.3E-90 T 09-03-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_RS29715 85b0cf44e9c3572efcf04b2f099d3d6e 305 SUPERFAMILY SSF56512 2 296 1.09E-94 T 09-03-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_RS29715 85b0cf44e9c3572efcf04b2f099d3d6e 305 Gene3D G3DSA:3.90.440.10 56 171 1.4E-28 T 09-03-2017 UA74_RS29715 85b0cf44e9c3572efcf04b2f099d3d6e 305 Gene3D G3DSA:3.90.1230.10 172 277 2.0E-23 T 09-03-2017 UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 SUPERFAMILY SSF52518 8 184 6.42E-30 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 469 562 2.9E-6 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 SUPERFAMILY SSF52518 468 579 1.0E-17 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 SUPERFAMILY SSF52518 368 430 1.0E-17 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 PIRSF PIRSF004983 1 596 1.2E-124 T 09-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Gene3D G3DSA:3.40.50.970 8 184 2.4E-45 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 590 31.031 T 09-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 181 4.9E-29 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 427 5.0E-101 T 09-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UA74_RS02475 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Gene3D G3DSA:3.40.50.970 337 577 6.9E-23 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 4.3E-17 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 SUPERFAMILY SSF46894 145 215 2.24E-20 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 Gene3D G3DSA:3.40.50.2300 2 152 3.2E-40 T 09-03-2017 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 SMART SM00421 151 208 4.5E-22 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 SUPERFAMILY SSF52172 2 133 2.28E-33 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.8E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.8E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.8E-11 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 Gene3D G3DSA:1.10.10.10 153 213 4.9E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 SMART SM00448 2 117 1.6E-31 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS22475 10ceabdcf396ab534225af1ca5b491e8 216 Pfam PF00072 Response regulator receiver domain 4 118 1.4E-27 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21115 89fe6c3b33147585350b8051e5313191 563 SMART SM00331 336 546 3.5E-27 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS21115 89fe6c3b33147585350b8051e5313191 563 Pfam PF00072 Response regulator receiver domain 17 129 2.8E-11 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21115 89fe6c3b33147585350b8051e5313191 563 SUPERFAMILY SSF81606 352 544 3.14E-9 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS21115 89fe6c3b33147585350b8051e5313191 563 Gene3D G3DSA:3.40.50.2300 14 137 6.2E-22 T 09-03-2017 UA74_RS21115 89fe6c3b33147585350b8051e5313191 563 SMART SM00448 15 129 1.0E-11 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS21115 89fe6c3b33147585350b8051e5313191 563 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 366 546 3.0E-42 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS21115 89fe6c3b33147585350b8051e5313191 563 SUPERFAMILY SSF52172 16 137 7.68E-22 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS27485 28075a1e81773a82582658029e682eb8 201 SMART SM00479 8 178 6.7E-33 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS27485 28075a1e81773a82582658029e682eb8 201 SUPERFAMILY SSF53098 8 190 3.71E-36 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS27485 28075a1e81773a82582658029e682eb8 201 Pfam PF00929 Exonuclease 10 169 1.4E-20 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS27485 28075a1e81773a82582658029e682eb8 201 Gene3D G3DSA:3.30.420.10 3 178 1.6E-40 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS28775 7492b4cb17ebe128efb05a766af9079b 242 SUPERFAMILY SSF52540 20 231 7.57E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28775 7492b4cb17ebe128efb05a766af9079b 242 Pfam PF00005 ABC transporter 35 180 9.7E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS28775 7492b4cb17ebe128efb05a766af9079b 242 SMART SM00382 41 230 4.3E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS28775 7492b4cb17ebe128efb05a766af9079b 242 Gene3D G3DSA:3.40.50.300 15 229 8.0E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 283 296 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 Gene3D G3DSA:3.20.20.70 52 444 5.7E-147 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 SUPERFAMILY SSF110921 501 598 2.75E-35 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 80 96 - T 09-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 SUPERFAMILY SSF89000 438 488 2.43E-14 T 09-03-2017 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 Pfam PF08502 LeuA allosteric (dimerisation) domain 472 598 3.2E-32 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 Pfam PF00682 HMGL-like 73 353 1.0E-77 T 09-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 SMART SM00917 472 599 1.3E-36 T 09-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 43 600 4.7E-263 T 09-03-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 44 600 54.852 T 09-03-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_RS01050 c60aec15c1008695637bb74311579c5a 600 SUPERFAMILY SSF51569 62 370 4.21E-97 T 09-03-2017 UA74_RS29990 c903b42f7bb3b489d3a28626d0c84180 109 Gene3D G3DSA:2.30.22.10 47 104 1.3E-8 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_RS29990 c903b42f7bb3b489d3a28626d0c84180 109 Pfam PF01025 GrpE 36 103 2.0E-7 T 09-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_RS29990 c903b42f7bb3b489d3a28626d0c84180 109 SUPERFAMILY SSF51064 49 104 3.27E-6 T 09-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 Pfam PF00005 ABC transporter 32 182 1.2E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 Pfam PF00005 ABC transporter 285 437 1.1E-14 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 SUPERFAMILY SSF52540 284 490 8.78E-34 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 SMART SM00382 292 484 2.5 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 SMART SM00382 41 238 4.3E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 SUPERFAMILY SSF52540 16 240 1.48E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 Gene3D G3DSA:3.40.50.300 284 489 7.5E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18290 14419017dcf69e57eaf3d666c2538787 507 Gene3D G3DSA:3.40.50.300 15 244 1.0E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20140 7b52ba2afa31d2eea90902ef57eea1fd 280 SUPERFAMILY SSF161098 2 280 3.27E-68 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20140 7b52ba2afa31d2eea90902ef57eea1fd 280 Gene3D G3DSA:1.10.3720.10 2 267 2.4E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20140 7b52ba2afa31d2eea90902ef57eea1fd 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 273 2.7E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 Gene3D G3DSA:3.40.220.10 18 146 4.7E-6 T 09-03-2017 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 154 461 7.2E-106 T 09-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 PRINTS PR00481 Cytosol aminopeptidase signature 313 333 3.3E-47 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 PRINTS PR00481 Cytosol aminopeptidase signature 254 275 3.3E-47 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 PRINTS PR00481 Cytosol aminopeptidase signature 232 249 3.3E-47 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 PRINTS PR00481 Cytosol aminopeptidase signature 291 312 3.3E-47 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 PRINTS PR00481 Cytosol aminopeptidase signature 342 357 3.3E-47 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 SUPERFAMILY SSF53187 150 465 4.71E-103 T 09-03-2017 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 Gene3D G3DSA:3.40.630.10 147 466 1.1E-113 T 09-03-2017 UA74_RS04590 55f9ec922d44dc1388e63a94b7bdfb09 471 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 317 324 - T 09-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_RS23845 a61ded0c2e3f8f85c857809ec62f4f71 625 Gene3D G3DSA:3.90.1310.10 223 330 2.0E-13 T 09-03-2017 UA74_RS23845 a61ded0c2e3f8f85c857809ec62f4f71 625 Pfam PF00905 Penicillin binding protein transpeptidase domain 346 615 2.8E-43 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_RS23845 a61ded0c2e3f8f85c857809ec62f4f71 625 Gene3D G3DSA:3.40.710.10 331 621 3.0E-60 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS23845 a61ded0c2e3f8f85c857809ec62f4f71 625 SUPERFAMILY SSF56519 139 324 2.75E-24 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UA74_RS23845 a61ded0c2e3f8f85c857809ec62f4f71 625 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 30 137 3.5E-11 T 09-03-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 UA74_RS23845 a61ded0c2e3f8f85c857809ec62f4f71 625 SUPERFAMILY SSF56601 280 619 4.73E-67 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS23845 a61ded0c2e3f8f85c857809ec62f4f71 625 Pfam PF03717 Penicillin-binding Protein dimerisation domain 145 302 3.0E-16 T 09-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 Pfam PF01126 Heme oxygenase 11 210 1.5E-49 T 09-03-2017 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 SUPERFAMILY SSF48613 10 217 1.67E-54 T 09-03-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 10 35 7.2E-24 T 09-03-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 45 70 7.2E-24 T 09-03-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 123 144 7.2E-24 T 09-03-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 165 186 7.2E-24 T 09-03-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 197 215 7.2E-24 T 09-03-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 70 95 7.2E-24 T 09-03-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 PIRSF PIRSF000343 1 220 1.1E-58 T 09-03-2017 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS29915 2f69e7553a8cabbce57115a8aa386414 234 Gene3D G3DSA:1.20.910.10 7 214 4.9E-55 T 09-03-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_RS27325 86ed784b1c62ecdf7838ad367aff3782 195 SUPERFAMILY SSF46689 6 78 1.3E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS27325 86ed784b1c62ecdf7838ad367aff3782 195 Gene3D G3DSA:1.10.10.60 8 44 1.1E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS27325 86ed784b1c62ecdf7838ad367aff3782 195 Gene3D G3DSA:1.10.357.10 45 187 6.4E-16 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS27325 86ed784b1c62ecdf7838ad367aff3782 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 6.2E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS10460 1eef6ddaf734004ca03a495a68f3a662 409 Pfam PF13439 Glycosyltransferase Family 4 21 197 5.4E-38 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS10460 1eef6ddaf734004ca03a495a68f3a662 409 Gene3D G3DSA:3.40.50.2000 184 370 2.1E-37 T 09-03-2017 UA74_RS10460 1eef6ddaf734004ca03a495a68f3a662 409 SUPERFAMILY SSF53756 1 392 1.33E-96 T 09-03-2017 UA74_RS10460 1eef6ddaf734004ca03a495a68f3a662 409 Pfam PF00534 Glycosyl transferases group 1 207 369 6.3E-39 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS28070 42e294beb6898c59fdb93775e34a81c1 315 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 34 80 1.0E-9 T 09-03-2017 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 SUPERFAMILY SSF50494 224 435 1.35E-55 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 Gene3D G3DSA:2.40.10.10 221 309 1.8E-26 T 09-03-2017 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 SUPERFAMILY SSF50156 411 512 3.02E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 SMART SM00228 440 512 1.0E-10 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 PRINTS PR00834 HtrA/DegQ protease family signature 259 271 4.4E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 PRINTS PR00834 HtrA/DegQ protease family signature 470 482 4.4E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 PRINTS PR00834 HtrA/DegQ protease family signature 324 348 4.4E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 PRINTS PR00834 HtrA/DegQ protease family signature 366 383 4.4E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 PRINTS PR00834 HtrA/DegQ protease family signature 283 303 4.4E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 PRINTS PR00834 HtrA/DegQ protease family signature 388 405 4.4E-45 T 09-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 Pfam PF13365 Trypsin-like peptidase domain 250 395 5.6E-32 T 09-03-2017 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 Gene3D G3DSA:2.30.42.10 444 526 4.6E-16 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 Gene3D G3DSA:2.40.10.10 316 443 5.4E-43 T 09-03-2017 UA74_RS03225 8017126f5205981afd0c79aa1ba62c4a 529 Pfam PF13180 PDZ domain 440 522 4.2E-14 T 09-03-2017 IPR001478 PDZ domain GO:0005515 UA74_RS21485 8c52b32555c3f19b667a4f2673a5ece4 402 Pfam PF07730 Histidine kinase 210 279 2.0E-12 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS21485 8c52b32555c3f19b667a4f2673a5ece4 402 SMART SM00387 313 402 9.4E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21485 8c52b32555c3f19b667a4f2673a5ece4 402 Gene3D G3DSA:3.30.565.10 315 401 1.2E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21485 8c52b32555c3f19b667a4f2673a5ece4 402 SUPERFAMILY SSF55874 292 400 2.74E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS21485 8c52b32555c3f19b667a4f2673a5ece4 402 Pfam PF13796 Putative sensor 8 180 6.9E-9 T 09-03-2017 IPR025828 Putative sensor domain UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 362 371 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 Gene3D G3DSA:1.10.630.10 16 420 3.0E-102 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 158 174 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 339 354 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 175 190 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 311 338 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 294 305 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 111 122 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 360 369 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 369 380 3.1E-37 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 SUPERFAMILY SSF48264 18 75 5.76E-77 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 SUPERFAMILY SSF48264 106 420 5.76E-77 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17530 7c5dfa4b21636af145589c4204e4b3c2 420 Pfam PF00067 Cytochrome P450 198 389 2.1E-12 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS27255 becfa8fec6a9c9a3054f838a7fc8f3a4 288 PIRSF PIRSF005295 2 259 3.5E-107 T 09-03-2017 IPR012022 Protein of unknown function UCP005295 UA74_RS27255 becfa8fec6a9c9a3054f838a7fc8f3a4 288 Pfam PF01026 TatD related DNase 4 228 2.1E-15 T 09-03-2017 IPR001130 TatD family GO:0016788 UA74_RS27255 becfa8fec6a9c9a3054f838a7fc8f3a4 288 Gene3D G3DSA:3.20.20.140 4 255 6.8E-39 T 09-03-2017 UA74_RS27255 becfa8fec6a9c9a3054f838a7fc8f3a4 288 SUPERFAMILY SSF51556 2 256 1.23E-54 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS12755 80a73c8d2decd138816170aacdd75f81 454 PIRSF PIRSF006060 6 439 1.6E-67 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 UA74_RS12755 80a73c8d2decd138816170aacdd75f81 454 Pfam PF00324 Amino acid permease 29 381 1.4E-36 T 09-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 Gene3D G3DSA:3.10.560.10 96 157 1.8E-9 T 09-03-2017 UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 SMART SM00278 197 216 0.016 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 SMART SM00278 227 246 3.8 T 09-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 Pfam PF12836 Helix-hairpin-helix motif 187 248 7.5E-23 T 09-03-2017 UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 SUPERFAMILY SSF47781 182 248 7.56E-28 T 09-03-2017 IPR010994 RuvA domain 2-like UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 Pfam PF10531 SLBB domain 102 156 1.3E-11 T 09-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 Gene3D G3DSA:1.10.150.320 181 248 2.5E-21 T 09-03-2017 UA74_RS08375 10d70e0cc11505bcb44ef83c09817426 249 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 187 248 1.4E-16 T 09-03-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain UA74_RS28580 3407ff055b377ebdecfb3dec9e588241 83 Pfam PF02597 ThiS family 5 83 3.5E-8 T 09-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 UA74_RS28580 3407ff055b377ebdecfb3dec9e588241 83 Gene3D G3DSA:3.10.20.30 2 83 8.0E-17 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS28580 3407ff055b377ebdecfb3dec9e588241 83 SUPERFAMILY SSF54285 2 81 4.45E-10 T 09-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 SUPERFAMILY SSF51905 5 171 6.76E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 SUPERFAMILY SSF51905 271 377 6.76E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 Gene3D G3DSA:3.50.50.60 272 345 6.4E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 Gene3D G3DSA:3.50.50.60 5 176 6.4E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 Pfam PF01494 FAD binding domain 6 339 2.2E-17 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 4.0E-10 T 09-03-2017 UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 4.0E-10 T 09-03-2017 UA74_RS04360 b83561db2156001bf25c7a07410fe778 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.0E-10 T 09-03-2017 UA74_RS12800 f6435b4e3662546698a17c324aa99a1c 180 SUPERFAMILY SSF51182 52 156 1.68E-20 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS12800 f6435b4e3662546698a17c324aa99a1c 180 Pfam PF07883 Cupin domain 67 122 6.2E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS12800 f6435b4e3662546698a17c324aa99a1c 180 Gene3D G3DSA:2.60.120.10 51 148 4.7E-23 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS04615 3121be6ede63af85f54e40552e9abd67 216 Pfam PF01596 O-methyltransferase 40 214 3.9E-27 T 09-03-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 UA74_RS04615 3121be6ede63af85f54e40552e9abd67 216 SUPERFAMILY SSF53335 37 214 1.09E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04615 3121be6ede63af85f54e40552e9abd67 216 Gene3D G3DSA:3.40.50.150 11 214 6.6E-51 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15500 540c2f4acc9d76e4f84f6a6093b9456c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 5.8E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15500 540c2f4acc9d76e4f84f6a6093b9456c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 5.8E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15500 540c2f4acc9d76e4f84f6a6093b9456c 198 SUPERFAMILY SSF46689 13 93 3.64E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15500 540c2f4acc9d76e4f84f6a6093b9456c 198 Gene3D G3DSA:1.10.357.10 15 195 5.0E-40 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15500 540c2f4acc9d76e4f84f6a6093b9456c 198 SUPERFAMILY SSF48498 92 195 9.85E-13 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS15500 540c2f4acc9d76e4f84f6a6093b9456c 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.6E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS08105 0ab35519fbb4edf5c20ab9a3cce20945 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 261 1.7E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08105 0ab35519fbb4edf5c20ab9a3cce20945 271 SUPERFAMILY SSF161098 18 263 1.85E-51 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08105 0ab35519fbb4edf5c20ab9a3cce20945 271 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 38 260 2.5E-71 T 09-03-2017 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 UA74_RS08105 0ab35519fbb4edf5c20ab9a3cce20945 271 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 60 263 7.6E-70 T 09-03-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 UA74_RS08105 0ab35519fbb4edf5c20ab9a3cce20945 271 Gene3D G3DSA:1.10.3720.10 15 260 3.7E-45 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23375 924504c4e15a046c9b390a92143c1844 369 Gene3D G3DSA:3.30.565.10 281 365 3.9E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23375 924504c4e15a046c9b390a92143c1844 369 SUPERFAMILY SSF55874 258 364 1.18E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23375 924504c4e15a046c9b390a92143c1844 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 281 325 2.4E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23375 924504c4e15a046c9b390a92143c1844 369 Pfam PF07730 Histidine kinase 170 235 2.6E-18 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS02015 47a0af54d65ef2b048e3283af8bd5c37 256 SUPERFAMILY SSF58113 56 190 3.92E-6 T 09-03-2017 UA74_RS02015 47a0af54d65ef2b048e3283af8bd5c37 256 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 71 168 2.0E-10 T 09-03-2017 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 SUPERFAMILY SSF53244 309 452 2.93E-24 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 Pfam PF08245 Mur ligase middle domain 54 280 1.5E-11 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 150 165 - T 09-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 448 9.3E-96 T 09-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 Gene3D G3DSA:3.40.1190.10 17 307 6.9E-89 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 PIRSF PIRSF001563 5 455 4.8E-111 T 09-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 385 1.3E-8 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 Gene3D G3DSA:3.90.190.20 309 452 5.7E-36 T 09-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_RS08225 c2d1012005e3ef762ac5096315f6f41b 455 SUPERFAMILY SSF53623 13 306 3.97E-86 T 09-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_RS12520 82d2c3fe287d3b8ebfbf1860d6bd529e 297 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 58 234 6.6E-19 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS12520 82d2c3fe287d3b8ebfbf1860d6bd529e 297 Gene3D G3DSA:3.40.50.1110 54 243 1.1E-21 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS12520 82d2c3fe287d3b8ebfbf1860d6bd529e 297 SUPERFAMILY SSF52266 54 243 2.96E-28 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 Gene3D G3DSA:3.40.50.300 433 665 2.9E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 SUPERFAMILY SSF90123 4 292 4.84E-27 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 Pfam PF00005 ABC transporter 450 597 3.3E-22 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 Pfam PF00664 ABC transporter transmembrane region 52 280 2.1E-6 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 SMART SM00382 458 641 2.0E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 ProSitePatterns PS00211 ABC transporters family signature. 569 583 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 SUPERFAMILY SSF52540 432 663 3.86E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13310 61bad80cac5884822e70b3a16ef5fb8b 688 Gene3D G3DSA:1.20.1560.10 4 285 1.0E-18 T 09-03-2017 UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 Pfam PF00106 short chain dehydrogenase 9 199 3.1E-45 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PIRSF PIRSF000126 1 267 3.1E-65 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.5E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.5E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.5E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.5E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.8E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.8E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.8E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 SUPERFAMILY SSF51735 3 257 1.59E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 Gene3D G3DSA:3.40.50.720 2 213 9.7E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16875 c5e9c327f0e14fc88036194dc5faae1c 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 194 2.5E-4 T 09-03-2017 UA74_RS09090 bea8cf4a80e6beb4940a677791ff18c7 287 SUPERFAMILY SSF161098 20 278 7.85E-50 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS09090 bea8cf4a80e6beb4940a677791ff18c7 287 Gene3D G3DSA:1.10.3720.10 21 278 2.4E-44 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS09090 bea8cf4a80e6beb4940a677791ff18c7 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 275 3.2E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS15080 87f5637a417404f73eade7d6cc250c54 288 Gene3D G3DSA:3.40.50.720 4 213 4.8E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15080 87f5637a417404f73eade7d6cc250c54 288 SUPERFAMILY SSF51735 4 248 1.08E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23550 9fb830bc5a55cdec93b21f7e067681b0 397 SMART SM00331 166 380 3.2E-14 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS23550 9fb830bc5a55cdec93b21f7e067681b0 397 SUPERFAMILY SSF81606 183 377 7.85E-7 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS23550 9fb830bc5a55cdec93b21f7e067681b0 397 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 194 380 1.9E-29 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS20590 bfff87368be8c6310abb8ea2197f3ea0 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 414 1.4E-99 T 09-03-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit UA74_RS20590 bfff87368be8c6310abb8ea2197f3ea0 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 420 3.3E-106 T 09-03-2017 IPR004681 TRAP transporter permease protein GO:0016021 UA74_RS20590 bfff87368be8c6310abb8ea2197f3ea0 425 PIRSF PIRSF006066 1 425 1.9E-122 T 09-03-2017 IPR004681 TRAP transporter permease protein GO:0016021 UA74_RS26755 93d0624b838248be89307dc06a7ef5f2 233 Pfam PF02223 Thymidylate kinase 27 185 2.2E-20 T 09-03-2017 UA74_RS26755 93d0624b838248be89307dc06a7ef5f2 233 Hamap MF_00165 Thymidylate kinase [tmk]. 23 232 13.403 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_RS26755 93d0624b838248be89307dc06a7ef5f2 233 SUPERFAMILY SSF52540 23 220 2.51E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26755 93d0624b838248be89307dc06a7ef5f2 233 Gene3D G3DSA:3.40.50.300 23 223 5.1E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01840 8790a6f724241888c1b2117f9bf07e80 201 Gene3D G3DSA:3.40.50.620 39 159 8.2E-13 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS01840 8790a6f724241888c1b2117f9bf07e80 201 Pfam PF02698 DUF218 domain 41 157 2.9E-16 T 09-03-2017 IPR003848 Domain of unknown function DUF218 UA74_RS15580 26ae7e1e936d594f719230e051300ec9 326 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 16 311 6.1E-97 T 09-03-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_RS15580 26ae7e1e936d594f719230e051300ec9 326 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS15580 26ae7e1e936d594f719230e051300ec9 326 SMART SM00382 32 217 8.4E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS15580 26ae7e1e936d594f719230e051300ec9 326 Pfam PF00005 ABC transporter 24 166 2.5E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS15580 26ae7e1e936d594f719230e051300ec9 326 Gene3D G3DSA:3.40.50.300 5 230 7.3E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15580 26ae7e1e936d594f719230e051300ec9 326 SUPERFAMILY SSF52540 7 230 1.25E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00840 9859f6c911a87daeb44404fb230da792 159 Pfam PF14437 MafB19-like deaminase 10 156 2.4E-28 T 09-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 UA74_RS00840 9859f6c911a87daeb44404fb230da792 159 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 14 157 46.359 T 09-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 UA74_RS00840 9859f6c911a87daeb44404fb230da792 159 SUPERFAMILY SSF53927 7 157 4.52E-49 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 UA74_RS00840 9859f6c911a87daeb44404fb230da792 159 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 60 98 - T 09-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UA74_RS00840 9859f6c911a87daeb44404fb230da792 159 Gene3D G3DSA:3.40.140.10 6 155 4.1E-57 T 09-03-2017 UA74_RS12275 fc254bc89d5e30d4154eaa5b7603032c 216 Pfam PF00156 Phosphoribosyl transferase domain 23 162 2.0E-18 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_RS12275 fc254bc89d5e30d4154eaa5b7603032c 216 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 15 192 35.605 T 09-03-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UA74_RS12275 fc254bc89d5e30d4154eaa5b7603032c 216 SUPERFAMILY SSF53271 21 186 8.15E-40 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS12275 fc254bc89d5e30d4154eaa5b7603032c 216 Gene3D G3DSA:3.40.50.2020 17 185 9.6E-46 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS05140 5a6ed95a1d4c557bcdc9bb475cb82992 280 Gene3D G3DSA:3.90.1200.10 110 217 2.6E-5 T 09-03-2017 UA74_RS05140 5a6ed95a1d4c557bcdc9bb475cb82992 280 SUPERFAMILY SSF56112 11 212 5.02E-20 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS16710 30bb14e59b71251bac756b4ffb29d0d3 150 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 131 9.4E-34 T 09-03-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 UA74_RS16710 30bb14e59b71251bac756b4ffb29d0d3 150 Gene3D G3DSA:3.40.930.10 3 146 2.2E-39 T 09-03-2017 IPR002178 PTS EIIA type-2 domain UA74_RS16710 30bb14e59b71251bac756b4ffb29d0d3 150 SUPERFAMILY SSF55804 3 144 8.76E-32 T 09-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 UA74_RS16710 30bb14e59b71251bac756b4ffb29d0d3 150 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 144 3.8E-30 T 09-03-2017 IPR002178 PTS EIIA type-2 domain UA74_RS28595 22d76be35a1cd5cd217793baa1bbcfc4 156 Gene3D G3DSA:3.30.70.640 2 154 3.8E-58 T 09-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 UA74_RS28595 22d76be35a1cd5cd217793baa1bbcfc4 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 148 1.2E-56 T 09-03-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 UA74_RS28595 22d76be35a1cd5cd217793baa1bbcfc4 156 SUPERFAMILY SSF55040 10 152 1.83E-50 T 09-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 UA74_RS28595 22d76be35a1cd5cd217793baa1bbcfc4 156 Pfam PF01967 MoaC family 14 147 1.4E-48 T 09-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 UA74_RS28595 22d76be35a1cd5cd217793baa1bbcfc4 156 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 1 155 32.97 T 09-03-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 UA74_RS13795 5340b76458c127e63f6bfaeb437c3750 146 SUPERFAMILY SSF103196 6 130 9.94E-29 T 09-03-2017 UA74_RS13795 5340b76458c127e63f6bfaeb437c3750 146 SMART SM00960 13 103 1.1E-29 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS13795 5340b76458c127e63f6bfaeb437c3750 146 Gene3D G3DSA:3.30.450.30 12 127 7.7E-21 T 09-03-2017 UA74_RS13795 5340b76458c127e63f6bfaeb437c3750 146 Pfam PF03259 Roadblock/LC7 domain 13 103 2.6E-20 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS22570 9e529f3e503201d3d8d58ddfea06a2b4 297 SUPERFAMILY SSF161098 90 277 1.03E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22570 9e529f3e503201d3d8d58ddfea06a2b4 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 296 4.7E-29 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22570 9e529f3e503201d3d8d58ddfea06a2b4 297 Gene3D G3DSA:1.10.3720.10 85 291 2.8E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS25560 77a72290819bb3efb59f35d48ceef586 431 Gene3D G3DSA:3.40.630.10 48 208 1.5E-32 T 09-03-2017 UA74_RS25560 77a72290819bb3efb59f35d48ceef586 431 Pfam PF00246 Zinc carboxypeptidase 55 170 1.8E-20 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS25560 77a72290819bb3efb59f35d48ceef586 431 SMART SM00631 47 268 2.5E-4 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS25560 77a72290819bb3efb59f35d48ceef586 431 SUPERFAMILY SSF53187 45 299 6.95E-40 T 09-03-2017 UA74_RS05660 9d88b46783122f04774650fe5df5421b 272 SUPERFAMILY SSF56112 95 238 1.0E-6 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS05660 9d88b46783122f04774650fe5df5421b 272 Gene3D G3DSA:3.90.1200.10 163 230 2.4E-4 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 4 488 1.1E-183 T 09-03-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 39 140 4.9E-19 T 09-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 SUPERFAMILY SSF51971 382 480 2.35E-10 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 470 1.3E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 Gene3D G3DSA:3.50.50.60 244 415 1.4E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 SUPERFAMILY SSF46548 6 164 1.26E-28 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 6.7E-24 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 178 191 6.7E-24 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 155 177 6.7E-24 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 220 230 6.7E-24 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 SUPERFAMILY SSF51971 153 415 9.81E-61 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 Gene3D G3DSA:1.10.1060.10 3 156 3.3E-32 T 09-03-2017 UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 Gene3D G3DSA:3.40.50.720 157 243 8.9E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21400 e7ff76e2e56f5d69a8677da52194b9d1 501 Gene3D G3DSA:3.40.50.720 417 490 8.9E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20215 d93b28dff29be9d5f7d924761a8fc674 530 SUPERFAMILY SSF53850 35 525 7.96E-115 T 09-03-2017 UA74_RS20215 d93b28dff29be9d5f7d924761a8fc674 530 Gene3D G3DSA:3.10.105.10 312 495 1.1E-47 T 09-03-2017 UA74_RS20215 d93b28dff29be9d5f7d924761a8fc674 530 Gene3D G3DSA:3.40.190.10 194 311 8.8E-29 T 09-03-2017 UA74_RS20215 d93b28dff29be9d5f7d924761a8fc674 530 Gene3D G3DSA:3.90.76.10 47 193 2.2E-29 T 09-03-2017 UA74_RS20215 d93b28dff29be9d5f7d924761a8fc674 530 PIRSF PIRSF002741 2 525 3.0E-87 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS20215 d93b28dff29be9d5f7d924761a8fc674 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 444 4.0E-68 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS01375 0d16ae00d37a4546b3ecf76d1c80ddd7 68 Pfam PF14029 Protein of unknown function (DUF4244) 13 65 4.5E-24 T 09-03-2017 IPR025338 Protein of unknown function DUF4244 UA74_RS27510 a52fef3743bd976931ab48556da9be6a 142 SUPERFAMILY SSF55811 16 130 3.52E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS27510 a52fef3743bd976931ab48556da9be6a 142 Pfam PF00293 NUDIX domain 18 125 8.2E-18 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS27510 a52fef3743bd976931ab48556da9be6a 142 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS27510 a52fef3743bd976931ab48556da9be6a 142 Gene3D G3DSA:3.90.79.10 17 126 5.9E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS27510 a52fef3743bd976931ab48556da9be6a 142 PRINTS PR00502 NUDIX hydrolase family signature 46 60 3.2E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS27510 a52fef3743bd976931ab48556da9be6a 142 PRINTS PR00502 NUDIX hydrolase family signature 60 75 3.2E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS02005 ed5fe84f9b3f3e33e201311fa2558633 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 12 121 5.8E-20 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_RS02005 ed5fe84f9b3f3e33e201311fa2558633 132 TIGRFAM TIGR00494 crcB: protein CrcB 12 123 2.1E-23 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_RS02005 ed5fe84f9b3f3e33e201311fa2558633 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 10 126 17.223 T 09-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_RS13725 abb770a3ede5b9f55e8782bd674964b8 260 Gene3D G3DSA:3.40.50.1580 15 254 9.6E-55 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS13725 abb770a3ede5b9f55e8782bd674964b8 260 SUPERFAMILY SSF53167 16 253 7.07E-52 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS13725 abb770a3ede5b9f55e8782bd674964b8 260 Pfam PF01048 Phosphorylase superfamily 29 249 8.8E-34 T 09-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_RS19640 6cfc0173bb4310a3fd10cdb43de4d9e3 212 SUPERFAMILY SSF51569 3 200 5.13E-58 T 09-03-2017 UA74_RS19640 6cfc0173bb4310a3fd10cdb43de4d9e3 212 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 3 201 5.4E-52 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS19640 6cfc0173bb4310a3fd10cdb43de4d9e3 212 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 122 135 - T 09-03-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS19640 6cfc0173bb4310a3fd10cdb43de4d9e3 212 Gene3D G3DSA:3.20.20.70 2 204 5.6E-69 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS19640 6cfc0173bb4310a3fd10cdb43de4d9e3 212 Pfam PF01081 KDPG and KHG aldolase 3 194 6.6E-43 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS18935 a816a4fb31955dafb6d45dcec6314fc1 398 Gene3D G3DSA:1.10.260.40 7 70 1.4E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18935 a816a4fb31955dafb6d45dcec6314fc1 398 SUPERFAMILY SSF47413 9 71 2.34E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18935 a816a4fb31955dafb6d45dcec6314fc1 398 SUPERFAMILY SSF48452 329 366 4.34E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18935 a816a4fb31955dafb6d45dcec6314fc1 398 SUPERFAMILY SSF48452 161 284 4.34E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18935 a816a4fb31955dafb6d45dcec6314fc1 398 Gene3D G3DSA:1.25.40.10 145 229 1.4E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS18935 a816a4fb31955dafb6d45dcec6314fc1 398 SMART SM00530 14 69 5.1E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS18935 a816a4fb31955dafb6d45dcec6314fc1 398 Pfam PF13560 Helix-turn-helix domain 11 68 6.1E-11 T 09-03-2017 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 SMART SM00863 660 704 1.2E-18 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF55186 559 719 3.79E-40 T 09-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF101353 249 442 2.09E-55 T 09-03-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 Pfam PF01411 tRNA synthetases class II (A) 5 562 7.6E-194 T 09-03-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 Pfam PF02272 DHHA1 domain 812 881 2.3E-6 T 09-03-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 162.815 T 09-03-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF50447 460 559 7.77E-17 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 3.7E-26 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 3.7E-26 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 3.7E-26 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 3.7E-26 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 3.7E-26 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 660 704 6.1E-16 T 09-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF55681 3 248 5.47E-87 T 09-03-2017 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 8.9E-238 T 09-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_RS12130 0f4777032937edd9fa73cb2a2bbca4d0 892 Gene3D G3DSA:3.30.930.10 2 244 8.9E-92 T 09-03-2017 UA74_RS17880 ee364a74fe0bbeca237fd34b243343b7 325 SUPERFAMILY SSF75005 38 316 2.28E-63 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS17880 ee364a74fe0bbeca237fd34b243343b7 325 Gene3D G3DSA:2.115.10.20 37 315 3.4E-69 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS17880 ee364a74fe0bbeca237fd34b243343b7 325 Pfam PF04616 Glycosyl hydrolases family 43 40 314 2.0E-44 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SMART SM00487 24 308 2.7E-4 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 609 645 8.1E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 14 124 8.1E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 209 265 8.1E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 Pfam PF13307 Helicase C-terminal domain 504 663 9.6E-28 T 09-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 Pfam PF00270 DEAD/DEAH box helicase 37 93 1.2E-5 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 Gene3D G3DSA:3.40.50.300 412 421 3.3E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 Gene3D G3DSA:3.40.50.300 197 269 3.3E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 Gene3D G3DSA:3.40.50.300 30 114 3.3E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 394 422 1.55E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 499 589 1.55E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 620 641 1.55E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 206 248 1.55E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06250 b65773549ed50273cb9fbd71518469db 682 SMART SM00491 521 650 7.0E-41 T 09-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UA74_RS06950 b5fe30b32c1ca772c495659fc7a293c1 321 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 109 1.9E-8 T 09-03-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 UA74_RS06950 b5fe30b32c1ca772c495659fc7a293c1 321 Gene3D G3DSA:3.40.50.720 2 193 5.3E-16 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 Pfam PF07690 Major Facilitator Superfamily 80 471 1.9E-54 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 Gene3D G3DSA:1.20.1250.20 76 254 4.6E-35 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 Gene3D G3DSA:1.20.1250.20 528 555 4.6E-23 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 Gene3D G3DSA:1.20.1250.20 324 483 4.6E-23 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 102 8.7E-9 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 PRINTS PR01036 Tetracycline resistance protein TetB signature 198 222 8.7E-9 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 PRINTS PR01036 Tetracycline resistance protein TetB signature 263 281 8.7E-9 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 PRINTS PR01036 Tetracycline resistance protein TetB signature 168 188 8.7E-9 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 PRINTS PR01036 Tetracycline resistance protein TetB signature 462 481 8.7E-9 T 09-03-2017 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 77 490 8.3E-78 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 SUPERFAMILY SSF103473 56 260 1.31E-73 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 SUPERFAMILY SSF103473 526 554 1.31E-73 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14185 ed6b64afc786d5613bf63b0a353a34ee 621 SUPERFAMILY SSF103473 309 481 1.31E-73 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS13590 1a91746f7ddb1a9ec6eacd3f44493f5d 291 SUPERFAMILY SSF56300 184 280 4.41E-29 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS13590 1a91746f7ddb1a9ec6eacd3f44493f5d 291 SUPERFAMILY SSF56300 19 144 4.41E-29 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS13590 1a91746f7ddb1a9ec6eacd3f44493f5d 291 Gene3D G3DSA:3.60.21.10 19 93 3.9E-24 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS13590 1a91746f7ddb1a9ec6eacd3f44493f5d 291 Gene3D G3DSA:3.60.21.10 187 274 3.9E-24 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS13590 1a91746f7ddb1a9ec6eacd3f44493f5d 291 Pfam PF00149 Calcineurin-like phosphoesterase 19 252 1.8E-15 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS14170 5d6dba5d26b88d4421d5e93960cf1649 432 Pfam PF07730 Histidine kinase 240 306 9.1E-13 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS14170 5d6dba5d26b88d4421d5e93960cf1649 432 Gene3D G3DSA:3.30.565.10 347 430 3.3E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS14170 5d6dba5d26b88d4421d5e93960cf1649 432 SUPERFAMILY SSF55874 342 429 9.58E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS14170 5d6dba5d26b88d4421d5e93960cf1649 432 Pfam PF13796 Putative sensor 38 210 1.0E-10 T 09-03-2017 IPR025828 Putative sensor domain UA74_RS27375 3a0cc38fe40188d9f95328894ac99473 120 Pfam PF03334 Na+/H+ antiporter subunit 11 89 3.9E-24 T 09-03-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 UA74_RS27375 3a0cc38fe40188d9f95328894ac99473 120 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 103 2.7E-22 T 09-03-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00097 Anthranilate synthase component II signature 99 107 6.3E-35 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00097 Anthranilate synthase component II signature 3 17 6.3E-35 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00097 Anthranilate synthase component II signature 46 55 6.3E-35 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00097 Anthranilate synthase component II signature 119 131 6.3E-35 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00097 Anthranilate synthase component II signature 74 85 6.3E-35 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00097 Anthranilate synthase component II signature 164 177 6.3E-35 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 2.9E-7 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.9E-7 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 Gene3D G3DSA:3.40.50.880 2 188 5.6E-64 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.2E-13 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.2E-13 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 2.2E-13 T 09-03-2017 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 Pfam PF00117 Glutamine amidotransferase class-I 5 185 7.1E-51 T 09-03-2017 IPR017926 Glutamine amidotransferase UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 185 7.5E-67 T 09-03-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS00105 ce753ae42a1e8e8d2f2d23492f7c290f 213 SUPERFAMILY SSF52317 2 188 5.47E-54 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS28375 992988a80d97f955b143ffe9d67151e2 90 Gene3D G3DSA:1.10.260.40 14 73 5.1E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28375 992988a80d97f955b143ffe9d67151e2 90 SMART SM00530 15 70 7.8E-12 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS28375 992988a80d97f955b143ffe9d67151e2 90 SUPERFAMILY SSF47413 12 74 1.04E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28375 992988a80d97f955b143ffe9d67151e2 90 Pfam PF01381 Helix-turn-helix 19 68 1.9E-11 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS09735 a6285aa09f10ac5049349cab02027427 246 Pfam PF08478 POTRA domain, FtsQ-type 56 123 1.9E-14 T 09-03-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type UA74_RS09735 a6285aa09f10ac5049349cab02027427 246 Pfam PF03799 Cell division protein FtsQ 137 231 8.6E-6 T 09-03-2017 IPR005548 Cell division protein FtsQ/DivIB UA74_RS20355 14f2cb3ae389a6639888b29877c8073e 432 SMART SM00387 216 330 0.0068 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20355 14f2cb3ae389a6639888b29877c8073e 432 Gene3D G3DSA:3.30.565.10 186 329 3.9E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20355 14f2cb3ae389a6639888b29877c8073e 432 SUPERFAMILY SSF55874 203 328 1.06E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS18835 eb3f3bc9e9522c828ab61f631bf4a7b0 340 SUPERFAMILY SSF51735 31 281 1.23E-21 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18835 eb3f3bc9e9522c828ab61f631bf4a7b0 340 Gene3D G3DSA:3.40.50.720 31 229 8.4E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16695 93cfd310923ce55af4ac18e41275cf5a 418 Gene3D G3DSA:1.20.1250.20 16 201 1.3E-17 T 09-03-2017 UA74_RS16695 93cfd310923ce55af4ac18e41275cf5a 418 Gene3D G3DSA:1.20.1250.20 227 404 1.5E-14 T 09-03-2017 UA74_RS16695 93cfd310923ce55af4ac18e41275cf5a 418 SUPERFAMILY SSF103473 17 405 1.7E-46 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16695 93cfd310923ce55af4ac18e41275cf5a 418 Pfam PF05977 Transmembrane secretion effector 17 400 1.3E-35 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS17490 be9832574563271981c7fef72021b3f3 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS17490 be9832574563271981c7fef72021b3f3 253 SUPERFAMILY SSF51735 5 252 1.31E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.1E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 Gene3D G3DSA:3.40.50.720 4 251 8.1E-77 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.1E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS17490 be9832574563271981c7fef72021b3f3 253 Pfam PF00106 short chain dehydrogenase 11 196 4.7E-57 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS28990 f8f15a1519c1c96377f0632961e80b87 181 SUPERFAMILY SSF51182 1 178 2.73E-55 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS28990 f8f15a1519c1c96377f0632961e80b87 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 173 9.2E-53 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_RS28990 f8f15a1519c1c96377f0632961e80b87 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 8 167 2.0E-45 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_RS28990 f8f15a1519c1c96377f0632961e80b87 181 Gene3D G3DSA:2.60.120.10 1 177 2.5E-59 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 218 5.3E-70 T 09-03-2017 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 3.8E-38 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 3.8E-38 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 3.8E-38 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 3.8E-38 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 Pfam PF01470 Pyroglutamyl peptidase 3 205 1.8E-64 T 09-03-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 206 35.862 T 09-03-2017 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 SUPERFAMILY SSF53182 1 219 7.06E-64 T 09-03-2017 UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 Gene3D G3DSA:3.40.630.20 2 212 1.1E-60 T 09-03-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like UA74_RS10345 dcab0edcc6be5b28b0d94b266ca1bef0 220 PIRSF PIRSF015592 1 217 5.6E-71 T 09-03-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 UA74_RS26605 a40a2d655ffcfaab945b65312e717dcc 302 SUPERFAMILY SSF53474 31 275 4.33E-41 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26605 a40a2d655ffcfaab945b65312e717dcc 302 Gene3D G3DSA:3.40.50.1820 47 279 4.1E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26605 a40a2d655ffcfaab945b65312e717dcc 302 Pfam PF07859 alpha/beta hydrolase fold 81 198 1.4E-14 T 09-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 UA74_RS22645 9e05a9c2a9f61bcf776d3719def439e0 242 SUPERFAMILY SSF144010 14 232 1.31E-50 T 09-03-2017 UA74_RS22645 9e05a9c2a9f61bcf776d3719def439e0 242 Gene3D G3DSA:3.30.1330.100 144 230 2.7E-36 T 09-03-2017 UA74_RS22645 9e05a9c2a9f61bcf776d3719def439e0 242 Gene3D G3DSA:3.30.1330.100 13 60 2.7E-36 T 09-03-2017 UA74_RS22645 9e05a9c2a9f61bcf776d3719def439e0 242 Pfam PF01996 F420-0:Gamma-glutamyl ligase 18 224 1.1E-40 T 09-03-2017 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_RS22645 9e05a9c2a9f61bcf776d3719def439e0 242 Gene3D G3DSA:3.90.1660.10 63 143 2.5E-18 T 09-03-2017 UA74_RS23340 6ce91dde07fe9236d4112a3513f3a4dc 305 SUPERFAMILY SSF63829 187 301 2.13E-12 T 09-03-2017 UA74_RS23340 6ce91dde07fe9236d4112a3513f3a4dc 305 SUPERFAMILY SSF63829 13 223 4.38E-28 T 09-03-2017 UA74_RS23340 6ce91dde07fe9236d4112a3513f3a4dc 305 PIRSF PIRSF026412 3 302 9.1E-100 T 09-03-2017 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 UA74_RS23340 6ce91dde07fe9236d4112a3513f3a4dc 305 Gene3D G3DSA:2.120.10.30 184 292 1.0E-9 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS23340 6ce91dde07fe9236d4112a3513f3a4dc 305 Gene3D G3DSA:2.120.10.30 17 181 2.3E-19 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS23340 6ce91dde07fe9236d4112a3513f3a4dc 305 Hamap MF_01282 Virginiamycin B lyase [vgb]. 14 301 43.436 T 09-03-2017 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 PIRSF PIRSF000077 2 108 8.4E-45 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 2.8E-40 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 Pfam PF00085 Thioredoxin 6 107 2.0E-35 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 SUPERFAMILY SSF52833 5 109 1.48E-40 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 PRINTS PR00421 Thioredoxin family signature 32 41 5.7E-9 T 09-03-2017 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 PRINTS PR00421 Thioredoxin family signature 24 32 5.7E-9 T 09-03-2017 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 PRINTS PR00421 Thioredoxin family signature 72 83 5.7E-9 T 09-03-2017 UA74_RS30405 00b24b1d2ddceb57db778d88ede1168f 109 Gene3D G3DSA:3.40.30.10 3 108 1.9E-39 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS21830 aa7e9caecc0596826c85de5cdf691d59 674 Pfam PF00823 PPE family 52 182 2.2E-10 T 09-03-2017 IPR000030 PPE family UA74_RS21830 aa7e9caecc0596826c85de5cdf691d59 674 SUPERFAMILY SSF140459 42 196 1.02E-12 T 09-03-2017 UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 Pfam PF00733 Asparagine synthase 241 605 3.7E-79 T 09-03-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 Gene3D G3DSA:3.40.50.620 224 398 8.4E-72 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 Gene3D G3DSA:3.40.50.620 462 579 8.4E-72 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 PIRSF PIRSF001589 1 613 6.9E-149 T 09-03-2017 UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 SUPERFAMILY SSF52402 220 392 1.07E-61 T 09-03-2017 UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 SUPERFAMILY SSF52402 455 580 1.07E-61 T 09-03-2017 UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 Pfam PF13537 Glutamine amidotransferase domain 49 170 2.6E-43 T 09-03-2017 IPR017932 Glutamine amidotransferase type 2 domain UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 Gene3D G3DSA:3.60.20.10 1 223 7.6E-74 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 SUPERFAMILY SSF56235 1 225 5.4E-61 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS11045 44b3dced95dbddfc2cbb45860fb52762 614 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 538 6.6E-150 T 09-03-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UA74_RS18475 d2c90b31796af97b915e11bdf86f0f5e 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 5.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18475 d2c90b31796af97b915e11bdf86f0f5e 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 5.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18475 d2c90b31796af97b915e11bdf86f0f5e 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 5.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18475 d2c90b31796af97b915e11bdf86f0f5e 318 Gene3D G3DSA:3.40.50.720 9 256 1.5E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18475 d2c90b31796af97b915e11bdf86f0f5e 318 SUPERFAMILY SSF51735 7 271 1.07E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18475 d2c90b31796af97b915e11bdf86f0f5e 318 Pfam PF00106 short chain dehydrogenase 15 221 1.9E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14055 0c24f00a8eec141c22d0e91cc7a5605d 290 Gene3D G3DSA:1.10.3720.10 81 285 1.3E-26 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS14055 0c24f00a8eec141c22d0e91cc7a5605d 290 SUPERFAMILY SSF161098 81 261 2.62E-25 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS14055 0c24f00a8eec141c22d0e91cc7a5605d 290 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 62 6.3E-6 T 09-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_RS14055 0c24f00a8eec141c22d0e91cc7a5605d 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 288 7.2E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS29495 09c3406de73cd7a50fd4900475fe8b96 107 SUPERFAMILY SSF103481 5 105 1.07E-18 T 09-03-2017 UA74_RS29495 09c3406de73cd7a50fd4900475fe8b96 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.6E-24 T 09-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 UA74_RS17065 2a056bbe088db931f4b9606668e3a565 560 Pfam PF05960 Bacterial protein of unknown function (DUF885) 30 543 2.7E-129 T 09-03-2017 IPR010281 Protein of unknown function DUF885 UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 SUPERFAMILY SSF53092 6 140 2.79E-21 T 09-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 SUPERFAMILY SSF55920 102 363 2.75E-73 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 PRINTS PR00599 Methionine aminopeptidase-1 signature 201 214 6.9E-8 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 PRINTS PR00599 Methionine aminopeptidase-1 signature 321 333 6.9E-8 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 PRINTS PR00599 Methionine aminopeptidase-1 signature 223 239 6.9E-8 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 Gene3D G3DSA:3.40.350.10 4 139 4.3E-22 T 09-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 Pfam PF00557 Metallopeptidase family M24 149 352 4.2E-62 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 141 7.6E-21 T 09-03-2017 IPR000587 Creatinase, N-terminal GO:0016787 UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 Gene3D G3DSA:3.90.230.10 141 368 1.6E-75 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS12255 797d0452aef0e6a808c49007a398dc90 369 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 299 311 - T 09-03-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site UA74_RS07295 1334be570a4880d29ff01a2ad0719ab7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 5.6E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS07295 1334be570a4880d29ff01a2ad0719ab7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 5.6E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS07295 1334be570a4880d29ff01a2ad0719ab7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 5.6E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS07295 1334be570a4880d29ff01a2ad0719ab7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 5.6E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS07295 1334be570a4880d29ff01a2ad0719ab7 264 Gene3D G3DSA:3.40.50.1820 10 260 3.7E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07295 1334be570a4880d29ff01a2ad0719ab7 264 Pfam PF00561 alpha/beta hydrolase fold 13 246 5.0E-24 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS07295 1334be570a4880d29ff01a2ad0719ab7 264 SUPERFAMILY SSF53474 8 259 8.04E-55 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14690 9e84e1565fdb3c14306ca1e7438d7ac5 341 Gene3D G3DSA:3.40.710.10 74 292 6.1E-29 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS14690 9e84e1565fdb3c14306ca1e7438d7ac5 341 SUPERFAMILY SSF56601 56 291 1.97E-23 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS14690 9e84e1565fdb3c14306ca1e7438d7ac5 341 Pfam PF13354 Beta-lactamase enzyme family 91 284 1.1E-35 T 09-03-2017 UA74_RS01965 5addc70afd1ec3755eba57e2196958a0 276 Gene3D G3DSA:1.10.3720.10 2 263 2.6E-72 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01965 5addc70afd1ec3755eba57e2196958a0 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 269 6.2E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01965 5addc70afd1ec3755eba57e2196958a0 276 SUPERFAMILY SSF161098 2 276 2.43E-78 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19145 44dff2fb6785aad899fa51ccd24aeea2 253 PIRSF PIRSF006648 1 253 1.4E-66 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS19145 44dff2fb6785aad899fa51ccd24aeea2 253 Pfam PF01061 ABC-2 type transporter 9 217 3.0E-21 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS17715 2c90751eec34d295c1d47d9d5a1247ed 629 Gene3D G3DSA:3.80.30.20 260 450 2.6E-16 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe UA74_RS17715 2c90751eec34d295c1d47d9d5a1247ed 629 TIGRFAM TIGR03975 rSAM_ocin_1: ribosomal peptide maturation radical SAM protein 1 3 602 7.4E-172 T 09-03-2017 IPR023984 Ribosomal peptide maturation radical SAM protein 1 UA74_RS17715 2c90751eec34d295c1d47d9d5a1247ed 629 SMART SM00729 260 475 4.7E-10 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS17715 2c90751eec34d295c1d47d9d5a1247ed 629 SUPERFAMILY SSF102114 260 456 1.49E-18 T 09-03-2017 UA74_RS17715 2c90751eec34d295c1d47d9d5a1247ed 629 Pfam PF02310 B12 binding domain 113 197 2.2E-10 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS22810 fcb26827cc85debc5d061e3e50c0f64c 436 Pfam PF00294 pfkB family carbohydrate kinase 216 402 4.2E-29 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS22810 fcb26827cc85debc5d061e3e50c0f64c 436 Pfam PF00294 pfkB family carbohydrate kinase 16 105 1.9E-14 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS22810 fcb26827cc85debc5d061e3e50c0f64c 436 SUPERFAMILY SSF53613 206 415 8.89E-45 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS22810 fcb26827cc85debc5d061e3e50c0f64c 436 Gene3D G3DSA:3.40.1190.20 209 416 3.2E-81 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS22810 fcb26827cc85debc5d061e3e50c0f64c 436 Gene3D G3DSA:3.40.1190.20 8 114 3.2E-81 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS22810 fcb26827cc85debc5d061e3e50c0f64c 436 SUPERFAMILY SSF53613 14 107 4.28E-18 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS22810 fcb26827cc85debc5d061e3e50c0f64c 436 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 359 372 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS24690 4ebb241867666e53569422d6afaf794c 251 Pfam PF13489 Methyltransferase domain 32 156 1.0E-10 T 09-03-2017 UA74_RS24690 4ebb241867666e53569422d6afaf794c 251 Gene3D G3DSA:3.40.50.150 22 178 1.0E-14 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24690 4ebb241867666e53569422d6afaf794c 251 SUPERFAMILY SSF53335 32 184 2.23E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09485 bdbc0456882eafd9787bcef8b0647e66 438 Pfam PF00675 Insulinase (Peptidase family M16) 20 167 1.0E-38 T 09-03-2017 IPR011765 Peptidase M16, N-terminal UA74_RS09485 bdbc0456882eafd9787bcef8b0647e66 438 SUPERFAMILY SSF63411 246 425 1.4E-39 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_RS09485 bdbc0456882eafd9787bcef8b0647e66 438 SUPERFAMILY SSF63411 10 218 4.02E-60 T 09-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_RS09485 bdbc0456882eafd9787bcef8b0647e66 438 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 41 64 - T 09-03-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 UA74_RS09485 bdbc0456882eafd9787bcef8b0647e66 438 Pfam PF05193 Peptidase M16 inactive domain 174 357 1.0E-40 T 09-03-2017 IPR007863 Peptidase M16, C-terminal UA74_RS09485 bdbc0456882eafd9787bcef8b0647e66 438 Gene3D G3DSA:3.30.830.10 245 427 3.9E-47 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 UA74_RS09485 bdbc0456882eafd9787bcef8b0647e66 438 Gene3D G3DSA:3.30.830.10 10 214 4.0E-60 T 09-03-2017 IPR011237 Peptidase M16 domain GO:0046872 UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 SMART SM00422 1 69 4.4E-20 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 Pfam PF13411 MerR HTH family regulatory protein 1 63 1.1E-15 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 SUPERFAMILY SSF46955 1 113 1.03E-23 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 Gene3D G3DSA:1.10.1660.10 1 112 5.0E-27 T 09-03-2017 UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.7E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.7E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS09200 0b81a0887e66684ce570098cf8461c55 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.7E-7 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15390 274dfa21b9750701ad4b5d484c069c2e 237 Gene3D G3DSA:3.40.50.300 2 218 7.7E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15390 274dfa21b9750701ad4b5d484c069c2e 237 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS15390 274dfa21b9750701ad4b5d484c069c2e 237 SUPERFAMILY SSF52540 2 219 7.26E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15390 274dfa21b9750701ad4b5d484c069c2e 237 Pfam PF00005 ABC transporter 18 156 6.3E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS15390 274dfa21b9750701ad4b5d484c069c2e 237 SMART SM00382 26 204 3.0E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16190 e7fb993f16c7fb0d778276a65c536cfb 284 SUPERFAMILY SSF52540 2 235 9.11E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16190 e7fb993f16c7fb0d778276a65c536cfb 284 Gene3D G3DSA:3.40.50.300 1 216 5.1E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08840 72699f0ced38ec6e5404caa8a9bfcd1c 216 Pfam PF12079 Protein of unknown function (DUF3558) 21 209 4.4E-8 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS22310 7e37ee1cc1dd50f81e76316a6666a8bd 449 Gene3D G3DSA:1.20.1250.20 6 189 1.3E-18 T 09-03-2017 UA74_RS22310 7e37ee1cc1dd50f81e76316a6666a8bd 449 Gene3D G3DSA:1.20.1250.20 209 394 2.6E-10 T 09-03-2017 UA74_RS22310 7e37ee1cc1dd50f81e76316a6666a8bd 449 Pfam PF07690 Major Facilitator Superfamily 14 356 2.2E-24 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS22310 7e37ee1cc1dd50f81e76316a6666a8bd 449 SUPERFAMILY SSF103473 6 394 8.5E-38 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS27150 ac56f6b1cd34d7dc1e7691010bffaea3 124 Pfam PF08044 Domain of unknown function (DUF1707) 1 53 5.0E-20 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS17070 84818a28f1559e50689663d071514b90 276 SMART SM00382 37 229 1.4E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS17070 84818a28f1559e50689663d071514b90 276 Pfam PF00005 ABC transporter 29 179 8.2E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS17070 84818a28f1559e50689663d071514b90 276 Gene3D G3DSA:3.40.50.300 5 253 4.7E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17070 84818a28f1559e50689663d071514b90 276 SUPERFAMILY SSF52540 9 251 1.02E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17070 84818a28f1559e50689663d071514b90 276 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 265 1.4E-7 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS17070 84818a28f1559e50689663d071514b90 276 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS11640 d608e24c92b5773ea8dfe9c53690756f 277 Pfam PF11296 Protein of unknown function (DUF3097) 10 272 4.5E-119 T 09-03-2017 IPR021447 Protein of unknown function DUF3097 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 Gene3D G3DSA:3.20.20.80 111 463 1.9E-66 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 Gene3D G3DSA:3.30.379.10 7 110 1.8E-13 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 Pfam PF00754 F5/8 type C domain 493 595 7.6E-15 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 SUPERFAMILY SSF51445 134 455 2.9E-69 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 SUPERFAMILY SSF55545 8 129 6.67E-14 T 09-03-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 135 397 2.6E-49 T 09-03-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 SUPERFAMILY SSF49785 494 597 2.34E-18 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 8 128 3.2E-17 T 09-03-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 Gene3D G3DSA:2.60.120.260 493 611 1.1E-18 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 PRINTS PR00738 Glycosyl hydrolase family 20 signature 255 273 9.5E-13 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 PRINTS PR00738 Glycosyl hydrolase family 20 signature 277 290 9.5E-13 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 PRINTS PR00738 Glycosyl hydrolase family 20 signature 154 175 9.5E-13 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS19940 25bfc73afef598c179ee85f65cab1f2a 615 PRINTS PR00738 Glycosyl hydrolase family 20 signature 90 110 9.5E-13 T 09-03-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_RS02880 0eb127160f5fc294464632d5ac98a163 320 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS02880 0eb127160f5fc294464632d5ac98a163 320 SUPERFAMILY SSF52540 23 248 7.04E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02880 0eb127160f5fc294464632d5ac98a163 320 SMART SM00382 49 227 6.5E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS02880 0eb127160f5fc294464632d5ac98a163 320 Pfam PF00005 ABC transporter 41 178 5.0E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS02880 0eb127160f5fc294464632d5ac98a163 320 Gene3D G3DSA:3.40.50.300 19 243 1.4E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23000 03a578d3832ec6c6e4c5a4591e466d72 443 Gene3D G3DSA:3.40.190.10 161 357 8.3E-52 T 09-03-2017 UA74_RS23000 03a578d3832ec6c6e4c5a4591e466d72 443 Gene3D G3DSA:3.40.190.10 37 160 2.5E-19 T 09-03-2017 UA74_RS23000 03a578d3832ec6c6e4c5a4591e466d72 443 SUPERFAMILY SSF53850 14 438 2.12E-78 T 09-03-2017 UA74_RS23000 03a578d3832ec6c6e4c5a4591e466d72 443 Pfam PF01547 Bacterial extracellular solute-binding protein 49 335 1.3E-50 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS20125 f9f3e0f4b5f5b58cf8e0a739e5c27b89 289 SUPERFAMILY SSF53474 20 276 4.25E-14 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20125 f9f3e0f4b5f5b58cf8e0a739e5c27b89 289 Pfam PF05448 Acetyl xylan esterase (AXE1) 3 233 1.6E-16 T 09-03-2017 IPR008391 Acetyl xylan esterase UA74_RS20125 f9f3e0f4b5f5b58cf8e0a739e5c27b89 289 Gene3D G3DSA:3.40.50.1820 3 233 7.4E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10490 16e3bbe467d0d515ebd178bf37925094 356 SUPERFAMILY SSF53756 4 338 2.04E-66 T 09-03-2017 UA74_RS10490 16e3bbe467d0d515ebd178bf37925094 356 Gene3D G3DSA:3.40.50.2000 4 154 1.7E-15 T 09-03-2017 UA74_RS10490 16e3bbe467d0d515ebd178bf37925094 356 Gene3D G3DSA:3.40.50.2000 173 338 3.1E-54 T 09-03-2017 UA74_RS10490 16e3bbe467d0d515ebd178bf37925094 356 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 75 316 2.5E-23 T 09-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 UA74_RS26000 0be0030659aeb141792d9592f052d85b 380 Gene3D G3DSA:3.40.640.10 10 254 1.2E-57 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS26000 0be0030659aeb141792d9592f052d85b 380 Gene3D G3DSA:3.90.1150.10 255 376 9.0E-26 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS26000 0be0030659aeb141792d9592f052d85b 380 SUPERFAMILY SSF53383 33 377 3.57E-70 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS26000 0be0030659aeb141792d9592f052d85b 380 PIRSF PIRSF001434 3 378 1.8E-97 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS26000 0be0030659aeb141792d9592f052d85b 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 375 4.9E-75 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS00250 94574ed839840ff957b04c2f77ff5349 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 239 5.7E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00250 94574ed839840ff957b04c2f77ff5349 248 Gene3D G3DSA:1.10.3720.10 19 241 9.3E-28 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00250 94574ed839840ff957b04c2f77ff5349 248 SUPERFAMILY SSF161098 47 234 2.22E-31 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01360 e7f1e76eca346265bda274e4dfdeaae7 425 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 41 384 1.0E-149 T 09-03-2017 IPR022399 Helicase/secretion neighbourhood ATPase UA74_RS01360 e7f1e76eca346265bda274e4dfdeaae7 425 Gene3D G3DSA:3.30.450.90 90 190 1.1E-22 T 09-03-2017 UA74_RS01360 e7f1e76eca346265bda274e4dfdeaae7 425 Gene3D G3DSA:3.40.50.300 199 384 1.2E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01360 e7f1e76eca346265bda274e4dfdeaae7 425 Pfam PF00437 Type II/IV secretion system protein 93 372 1.9E-69 T 09-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 UA74_RS01360 e7f1e76eca346265bda274e4dfdeaae7 425 SUPERFAMILY SSF52540 75 378 3.6E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14275 11d708c38be1226de630349ea692a693 224 SUPERFAMILY SSF56420 36 201 1.57E-53 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 Hamap MF_00163 Peptide deformylase [def]. 37 204 28.334 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 41 201 4.7E-38 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 131 142 3.9E-35 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 143 161 3.9E-35 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 69 98 3.9E-35 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 162 191 3.9E-35 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 Gene3D G3DSA:3.90.45.10 40 208 3.4E-55 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS14275 11d708c38be1226de630349ea692a693 224 Pfam PF01327 Polypeptide deformylase 39 194 1.6E-45 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS09405 55283e674660864ae75b89f0f6905a62 87 Pfam PF16827 zinc-finger 20 75 6.8E-6 T 09-03-2017 IPR031795 Putative zinc-finger containing protein UA74_RS17595 7488988146acce9411be7495a113c966 420 SUPERFAMILY SSF48264 14 404 1.83E-95 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 Pfam PF00067 Cytochrome P450 207 372 1.7E-24 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 Gene3D G3DSA:1.10.630.10 14 405 2.2E-124 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 274 285 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 137 153 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 154 169 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 320 335 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 91 102 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 292 319 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 193 215 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 342 351 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 351 362 8.6E-53 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17595 7488988146acce9411be7495a113c966 420 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS07630 35a715eeba4315c2e31714afa6f37a1a 212 Pfam PF12680 SnoaL-like domain 115 198 4.5E-7 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS07630 35a715eeba4315c2e31714afa6f37a1a 212 SUPERFAMILY SSF54427 108 205 3.86E-11 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS07630 35a715eeba4315c2e31714afa6f37a1a 212 Gene3D G3DSA:3.10.450.50 108 205 2.4E-11 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS21015 ecadac03cd3f7f326745c3638c3e4f36 146 Gene3D G3DSA:1.10.10.10 6 135 1.5E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21015 ecadac03cd3f7f326745c3638c3e4f36 146 SUPERFAMILY SSF46785 6 135 6.14E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05620 affc85f634921896645176b99ff82abc 444 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 135 2.9E-5 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS05620 affc85f634921896645176b99ff82abc 444 SUPERFAMILY SSF51604 137 413 4.98E-77 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS05620 affc85f634921896645176b99ff82abc 444 Gene3D G3DSA:3.20.20.120 121 396 6.7E-99 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS05620 affc85f634921896645176b99ff82abc 444 SUPERFAMILY SSF54826 6 135 6.01E-31 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS05620 affc85f634921896645176b99ff82abc 444 SMART SM00922 184 284 4.3E-14 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS05620 affc85f634921896645176b99ff82abc 444 Pfam PF13378 Enolase C-terminal domain-like 190 403 3.4E-38 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS05620 affc85f634921896645176b99ff82abc 444 Gene3D G3DSA:3.30.390.10 34 120 7.5E-10 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS11250 001460fc81f1a09fc1cd3ba25d9e01a7 450 PIRSF PIRSF000521 3 449 7.1E-149 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS11250 001460fc81f1a09fc1cd3ba25d9e01a7 450 SUPERFAMILY SSF53383 37 446 3.17E-79 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS11250 001460fc81f1a09fc1cd3ba25d9e01a7 450 TIGRFAM TIGR03251 LAT_fam: L-lysine 6-transaminase 15 446 2.3E-208 T 09-03-2017 IPR017657 L-lysine 6-transaminase GO:0017000|GO:0030170|GO:0045484 MetaCyc: PWY-5298 UA74_RS11250 001460fc81f1a09fc1cd3ba25d9e01a7 450 Gene3D G3DSA:3.90.1150.10 339 448 2.6E-18 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS11250 001460fc81f1a09fc1cd3ba25d9e01a7 450 Gene3D G3DSA:3.40.640.10 77 338 5.7E-65 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS11250 001460fc81f1a09fc1cd3ba25d9e01a7 450 Pfam PF00202 Aminotransferase class-III 32 445 5.1E-77 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS01060 195973f016854a0275f11ce6fff0fb77 207 Pfam PF00881 Nitroreductase family 26 87 7.0E-10 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_RS01060 195973f016854a0275f11ce6fff0fb77 207 Pfam PF00881 Nitroreductase family 114 168 4.5E-7 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_RS01060 195973f016854a0275f11ce6fff0fb77 207 SUPERFAMILY SSF55469 20 204 8.9E-38 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS01060 195973f016854a0275f11ce6fff0fb77 207 Gene3D G3DSA:3.40.109.10 20 204 3.2E-38 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS24900 9c0e350ce14cc3e89a1fdf2be340c3ab 573 Gene3D G3DSA:1.10.287.1060 74 124 2.7E-4 T 09-03-2017 UA74_RS24900 9c0e350ce14cc3e89a1fdf2be340c3ab 573 SUPERFAMILY SSF140453 74 162 9.68E-8 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS03300 9ebb1beae99999470dd74f288583da33 145 Pfam PF00400 WD domain, G-beta repeat 71 99 2.4E-6 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS03300 9ebb1beae99999470dd74f288583da33 145 SMART SM00320 62 100 1.1E-5 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS03300 9ebb1beae99999470dd74f288583da33 145 SUPERFAMILY SSF50978 65 108 8.97E-7 T 09-03-2017 IPR017986 WD40-repeat-containing domain GO:0005515 UA74_RS03300 9ebb1beae99999470dd74f288583da33 145 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 87 101 - T 09-03-2017 IPR019775 WD40 repeat, conserved site UA74_RS03300 9ebb1beae99999470dd74f288583da33 145 Gene3D G3DSA:2.130.10.10 30 105 1.2E-9 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 Pfam PF01680 SOR/SNZ family 18 223 9.7E-108 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 Gene3D G3DSA:3.20.20.70 203 289 2.6E-50 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 Gene3D G3DSA:3.20.20.70 35 171 2.6E-50 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 15 305 53.57 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 20 305 5.1E-146 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 PIRSF PIRSF029271 8 305 6.6E-152 T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 ProSitePatterns PS01235 PdxS/SNZ family signature. 216 234 - T 09-03-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_RS10865 b029c64cc07d0595c480988c47287fde 305 SUPERFAMILY SSF51366 29 275 2.82E-63 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 UA74_RS26260 f83b3ec5a578b17a69b4ae80c0168fe1 372 SUPERFAMILY SSF52540 1 139 3.43E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26260 f83b3ec5a578b17a69b4ae80c0168fe1 372 SUPERFAMILY SSF52540 180 312 3.43E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26260 f83b3ec5a578b17a69b4ae80c0168fe1 372 Gene3D G3DSA:3.40.50.300 259 313 6.5E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26260 f83b3ec5a578b17a69b4ae80c0168fe1 372 Pfam PF13175 AAA ATPase domain 244 309 4.9E-12 T 09-03-2017 UA74_RS26260 f83b3ec5a578b17a69b4ae80c0168fe1 372 Pfam PF12476 Protein of unknown function (DUF3696) 325 370 1.6E-13 T 09-03-2017 IPR022532 Domain of unknown function DUF3696, C-terminal UA74_RS26260 f83b3ec5a578b17a69b4ae80c0168fe1 372 Gene3D G3DSA:3.40.50.300 1 50 4.3E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26260 f83b3ec5a578b17a69b4ae80c0168fe1 372 PIRSF PIRSF034888 1 371 3.9E-48 T 09-03-2017 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 SMART SM00382 311 480 1.3E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 SMART SM00382 29 199 1.5E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 SUPERFAMILY SSF52540 5 203 1.46E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 Pfam PF16326 ABC transporter C-terminal domain 540 598 8.0E-8 T 09-03-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 Pfam PF00005 ABC transporter 20 155 4.5E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 Pfam PF00005 ABC transporter 303 436 2.4E-23 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 Gene3D G3DSA:3.40.50.300 285 498 1.3E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 Gene3D G3DSA:3.40.50.300 4 229 3.0E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03590 9b9f033b86f3bc4e2eff79068658e2eb 606 SUPERFAMILY SSF52540 271 484 1.73E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 SUPERFAMILY SSF55874 284 414 8.25E-20 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 Gene3D G3DSA:3.30.565.10 285 416 2.6E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 4.9E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 4.9E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 4.9E-5 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 Pfam PF07730 Histidine kinase 215 280 3.0E-15 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 SMART SM00387 319 416 1.0E-5 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 415 2.2E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03405 e39bf69aff767ce068375faffbe4d1d5 425 PIRSF PIRSF037434 7 421 1.5E-62 T 09-03-2017 IPR017205 Signal transduction histidine kinase, ChrS UA74_RS06995 4637ec10b72d314b11d5162dd79ee191 88 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 85 19.392 T 09-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 UA74_RS06995 4637ec10b72d314b11d5162dd79ee191 88 Pfam PF02416 mttA/Hcf106 family 4 52 2.6E-14 T 09-03-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 UA74_RS15545 4c605cebef1e23c7a21cbd25fae4312b 199 SUPERFAMILY SSF55961 22 160 6.25E-28 T 09-03-2017 UA74_RS15545 4c605cebef1e23c7a21cbd25fae4312b 199 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 153 6.1E-12 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS15545 4c605cebef1e23c7a21cbd25fae4312b 199 Gene3D G3DSA:3.30.530.20 19 160 3.5E-31 T 09-03-2017 IPR023393 START-like domain UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 Pfam PF00294 pfkB family carbohydrate kinase 231 338 3.5E-24 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 Pfam PF00294 pfkB family carbohydrate kinase 5 209 1.6E-39 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 SUPERFAMILY SSF53613 5 203 4.12E-75 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 SUPERFAMILY SSF53613 246 343 4.12E-75 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 290 303 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 Hamap MF_01987 Ribokinase [rbsK]. 5 344 24.187 T 09-03-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 PRINTS PR00990 Ribokinase signature 107 120 1.4E-25 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 PRINTS PR00990 Ribokinase signature 36 55 1.4E-25 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 PRINTS PR00990 Ribokinase signature 175 190 1.4E-25 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 PRINTS PR00990 Ribokinase signature 9 30 1.4E-25 T 09-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 Gene3D G3DSA:3.40.1190.20 244 342 6.2E-89 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS30305 67e9748991688117f1554a6c1f93e51e 344 Gene3D G3DSA:3.40.1190.20 5 196 6.2E-89 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1187 1260 2.0E-21 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 605 640 1.0E-7 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 478 508 4.8E-5 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 812 846 1.2E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 393 425 1.1E-5 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 562 598 7.7E-8 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 709 746 8.2E-12 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 464 493 1.6E-5 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 520 556 1.1E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF03527 RHS protein 1159 1191 2.8E-8 T 09-03-2017 IPR001826 RHS protein UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 520 560 8.2E-9 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 562 602 7.5E-9 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 793 826 1.7E-5 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 414 443 0.0018 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 464 498 5.1E-7 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 688 723 1.5E-5 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 605 644 5.5E-7 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 709 749 2.3E-10 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 499 539 8.0E-6 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 541 576 3.2E-8 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 812 846 0.0031 T 09-03-2017 IPR006530 YD repeat UA74_RS24905 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 393 427 8.8E-6 T 09-03-2017 IPR006530 YD repeat UA74_RS13475 11fec5dbdd2c0feef4482371609c7a12 220 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS13475 11fec5dbdd2c0feef4482371609c7a12 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.6E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13475 11fec5dbdd2c0feef4482371609c7a12 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.6E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13475 11fec5dbdd2c0feef4482371609c7a12 220 Gene3D G3DSA:1.10.10.60 6 61 1.5E-19 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13475 11fec5dbdd2c0feef4482371609c7a12 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 3.2E-15 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS13475 11fec5dbdd2c0feef4482371609c7a12 220 SUPERFAMILY SSF46689 5 78 7.28E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13475 11fec5dbdd2c0feef4482371609c7a12 220 Gene3D G3DSA:1.10.357.10 62 199 8.0E-30 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 Gene3D G3DSA:1.10.10.60 206 261 1.6E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 SUPERFAMILY SSF46689 208 257 1.97E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 SUPERFAMILY SSF46689 260 309 8.96E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 Gene3D G3DSA:1.10.10.60 262 309 4.2E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 Pfam PF12852 Cupin 2 192 1.1E-53 T 09-03-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 303 - T 09-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 SMART SM00342 224 307 2.6E-29 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS02755 4c75f2d7f6ee773829d1c78b1de35cc3 313 Pfam PF12833 Helix-turn-helix domain 230 308 4.4E-20 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS05655 1ccdadd697754feeeac86574106b1a95 405 Gene3D G3DSA:2.60.120.650 32 226 3.8E-23 T 09-03-2017 UA74_RS05655 1ccdadd697754feeeac86574106b1a95 405 SUPERFAMILY SSF51197 72 269 2.47E-31 T 09-03-2017 UA74_RS05655 1ccdadd697754feeeac86574106b1a95 405 Pfam PF08007 Cupin superfamily protein 128 274 1.2E-27 T 09-03-2017 IPR003347 JmjC domain UA74_RS14875 2b6ad971047f444573453fba6c445b81 161 SUPERFAMILY SSF55729 3 158 3.24E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14875 2b6ad971047f444573453fba6c445b81 161 Pfam PF13302 Acetyltransferase (GNAT) domain 3 136 9.9E-20 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS14875 2b6ad971047f444573453fba6c445b81 161 Gene3D G3DSA:3.40.630.30 3 138 2.5E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS16245 17568888f8c1e4f540554823fce8c660 389 Pfam PF07728 AAA domain (dynein-related subfamily) 162 290 4.5E-15 T 09-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_RS16245 17568888f8c1e4f540554823fce8c660 389 SUPERFAMILY SSF52540 150 315 6.54E-18 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16245 17568888f8c1e4f540554823fce8c660 389 Gene3D G3DSA:3.40.50.300 151 297 2.9E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18490 14f3822240f8e06a02b17229afa183bc 258 SUPERFAMILY SSF53474 2 256 1.4E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18490 14f3822240f8e06a02b17229afa183bc 258 Gene3D G3DSA:3.40.50.1820 3 256 3.1E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18490 14f3822240f8e06a02b17229afa183bc 258 Pfam PF12697 Alpha/beta hydrolase family 23 242 6.7E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS03905 fa83751b863a1ebce758e0c1effa77bf 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 293 5.8E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03905 fa83751b863a1ebce758e0c1effa77bf 302 SUPERFAMILY SSF161098 34 298 6.28E-72 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03905 fa83751b863a1ebce758e0c1effa77bf 302 Gene3D G3DSA:1.10.3720.10 25 288 1.1E-66 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS06505 597a3048c94ec22213c16d447c6216db 137 SUPERFAMILY SSF50475 2 135 1.48E-23 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS06505 597a3048c94ec22213c16d447c6216db 137 Gene3D G3DSA:2.30.110.10 5 135 5.3E-23 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS06505 597a3048c94ec22213c16d447c6216db 137 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 87 3.3E-12 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS06505 597a3048c94ec22213c16d447c6216db 137 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 135 3.3E-31 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 Gene3D G3DSA:3.40.50.300 256 493 2.6E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 Gene3D G3DSA:3.40.50.300 7 222 1.3E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 SMART SM00382 281 475 9.0E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 SMART SM00382 34 222 3.1E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 SUPERFAMILY SSF52540 8 223 5.65E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 Pfam PF00005 ABC transporter 25 174 1.3E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 Pfam PF00005 ABC transporter 273 426 2.0E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 SUPERFAMILY SSF52540 249 487 4.39E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30315 04bd4e1228ce1dcb9413293a50ee1a91 505 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS08870 5fad602b00387102a85b513e47efee38 227 SUPERFAMILY SSF52172 3 176 3.13E-38 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS08870 5fad602b00387102a85b513e47efee38 227 Pfam PF00072 Response regulator receiver domain 5 112 6.1E-26 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS08870 5fad602b00387102a85b513e47efee38 227 SMART SM00448 2 112 1.3E-34 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS08870 5fad602b00387102a85b513e47efee38 227 SMART SM00862 146 222 2.2E-26 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS08870 5fad602b00387102a85b513e47efee38 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 7.3E-24 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS08870 5fad602b00387102a85b513e47efee38 227 Gene3D G3DSA:1.10.10.10 124 224 1.1E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08870 5fad602b00387102a85b513e47efee38 227 Gene3D G3DSA:3.40.50.2300 3 123 1.6E-36 T 09-03-2017 UA74_RS27885 fb543d76f415c7c874586b65cef37b62 230 Gene3D G3DSA:2.70.70.10 86 224 1.4E-42 T 09-03-2017 UA74_RS27885 fb543d76f415c7c874586b65cef37b62 230 SUPERFAMILY SSF51261 91 223 9.94E-46 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS27885 fb543d76f415c7c874586b65cef37b62 230 Pfam PF01551 Peptidase family M23 123 219 9.8E-31 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS05375 a1bd8245fed7fcaf25c17f9dfa43aa24 318 SUPERFAMILY SSF53474 49 314 2.41E-52 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05375 a1bd8245fed7fcaf25c17f9dfa43aa24 318 Pfam PF07859 alpha/beta hydrolase fold 89 294 2.9E-49 T 09-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 UA74_RS05375 a1bd8245fed7fcaf25c17f9dfa43aa24 318 Gene3D G3DSA:3.40.50.1820 49 316 6.6E-65 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12605 86d4d8d58f898eb7ce1780507ddb53da 265 Gene3D G3DSA:1.10.10.10 22 123 6.0E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12605 86d4d8d58f898eb7ce1780507ddb53da 265 Pfam PF01022 Bacterial regulatory protein, arsR family 29 61 4.6E-5 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS12605 86d4d8d58f898eb7ce1780507ddb53da 265 SUPERFAMILY SSF46785 20 205 2.08E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02180 735c3ac7d7cf23f7783a3f7db63194bd 253 SUPERFAMILY SSF54593 15 186 9.42E-26 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS02180 735c3ac7d7cf23f7783a3f7db63194bd 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 146 247 6.7E-5 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS02180 735c3ac7d7cf23f7783a3f7db63194bd 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 121 2.0E-7 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS02180 735c3ac7d7cf23f7783a3f7db63194bd 253 Gene3D G3DSA:3.10.180.10 144 252 1.2E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS02180 735c3ac7d7cf23f7783a3f7db63194bd 253 Gene3D G3DSA:3.10.180.10 12 125 3.9E-35 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 Pfam PF04820 Tryptophan halogenase 5 480 4.4E-145 T 09-03-2017 IPR006905 Tryptophan halogenase UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 SUPERFAMILY SSF51905 338 423 2.3E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 SUPERFAMILY SSF51905 155 248 2.3E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 SUPERFAMILY SSF51905 3 86 2.3E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 PIRSF PIRSF011396 1 519 5.7E-153 T 09-03-2017 IPR006905 Tryptophan halogenase UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 Gene3D G3DSA:3.50.50.60 168 247 8.6E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 Gene3D G3DSA:3.50.50.60 4 71 8.6E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16895 1b5b1b576a6781c5dc6c2d113aad19dd 522 Gene3D G3DSA:3.50.50.60 333 377 8.6E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS22295 4645eaea18c15f6610d08d4742aed901 194 Pfam PF07883 Cupin domain 116 177 8.6E-15 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS22295 4645eaea18c15f6610d08d4742aed901 194 SUPERFAMILY SSF47413 7 77 3.66E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22295 4645eaea18c15f6610d08d4742aed901 194 SMART SM00530 15 70 1.2E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS22295 4645eaea18c15f6610d08d4742aed901 194 Pfam PF13560 Helix-turn-helix domain 11 69 1.2E-12 T 09-03-2017 UA74_RS22295 4645eaea18c15f6610d08d4742aed901 194 SUPERFAMILY SSF51182 67 177 9.24E-23 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS22295 4645eaea18c15f6610d08d4742aed901 194 Gene3D G3DSA:1.10.260.40 9 79 9.3E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22295 4645eaea18c15f6610d08d4742aed901 194 Gene3D G3DSA:2.60.120.10 88 181 7.4E-15 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS25225 3c388e49dec3ecb03e19d0c4ddc7d103 258 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 89 141 5.0E-18 T 09-03-2017 UA74_RS25225 3c388e49dec3ecb03e19d0c4ddc7d103 258 Pfam PF03099 Biotin/lipoate A/B protein ligase family 68 178 1.2E-9 T 09-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 UA74_RS25225 3c388e49dec3ecb03e19d0c4ddc7d103 258 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 45 214 7.2E-40 T 09-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_RS25225 3c388e49dec3ecb03e19d0c4ddc7d103 258 Hamap MF_00013 Octanoyltransferase [lipB]. 19 226 33.979 T 09-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_RS25225 3c388e49dec3ecb03e19d0c4ddc7d103 258 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 85 100 - T 09-03-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UA74_RS25225 3c388e49dec3ecb03e19d0c4ddc7d103 258 Gene3D G3DSA:3.90.1550.10 19 221 3.1E-74 T 09-03-2017 UA74_RS25225 3c388e49dec3ecb03e19d0c4ddc7d103 258 SUPERFAMILY SSF55681 18 224 9.11E-66 T 09-03-2017 UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 Gene3D G3DSA:1.20.1560.10 31 303 2.8E-29 T 09-03-2017 UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 Pfam PF00664 ABC transporter transmembrane region 89 253 1.0E-15 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 Gene3D G3DSA:3.40.50.300 383 598 1.6E-68 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 ProSitePatterns PS00211 ABC transporters family signature. 522 536 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 SUPERFAMILY SSF52540 382 598 5.53E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 SMART SM00382 410 596 1.2E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 SUPERFAMILY SSF90123 19 290 1.07E-34 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS23395 5071dd0e49c2237739244c2a9006396a 663 Pfam PF00005 ABC transporter 401 550 6.7E-35 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS11975 1b7dfc638b1842507099f6ff77bbbdfd 301 Gene3D G3DSA:1.10.10.60 217 268 2.3E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11975 1b7dfc638b1842507099f6ff77bbbdfd 301 SUPERFAMILY SSF46689 212 262 7.83E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11975 1b7dfc638b1842507099f6ff77bbbdfd 301 Pfam PF12833 Helix-turn-helix domain 234 296 1.7E-11 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS11975 1b7dfc638b1842507099f6ff77bbbdfd 301 SUPERFAMILY SSF52317 3 193 1.95E-42 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS11975 1b7dfc638b1842507099f6ff77bbbdfd 301 Pfam PF01965 DJ-1/PfpI family 3 172 4.2E-20 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS11975 1b7dfc638b1842507099f6ff77bbbdfd 301 SMART SM00342 228 300 0.0014 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS11975 1b7dfc638b1842507099f6ff77bbbdfd 301 Gene3D G3DSA:3.40.50.880 3 216 4.3E-49 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS28565 70285d2412b9b3b6265e09d68b6eb197 243 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 2 218 9.2E-45 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_RS28565 70285d2412b9b3b6265e09d68b6eb197 243 Pfam PF13344 Haloacid dehalogenase-like hydrolase 1 96 2.5E-22 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_RS28565 70285d2412b9b3b6265e09d68b6eb197 243 Pfam PF13242 HAD-hyrolase-like 169 242 1.3E-23 T 09-03-2017 UA74_RS28565 70285d2412b9b3b6265e09d68b6eb197 243 Gene3D G3DSA:3.40.50.1000 1 70 1.0E-38 T 09-03-2017 IPR023214 HAD-like domain UA74_RS28565 70285d2412b9b3b6265e09d68b6eb197 243 Gene3D G3DSA:3.40.50.1000 169 243 1.0E-38 T 09-03-2017 IPR023214 HAD-like domain UA74_RS28565 70285d2412b9b3b6265e09d68b6eb197 243 Gene3D G3DSA:3.40.50.10410 75 168 6.0E-33 T 09-03-2017 IPR023215 Nitrophenylphosphatase-like domain UA74_RS28565 70285d2412b9b3b6265e09d68b6eb197 243 SUPERFAMILY SSF56784 1 242 5.11E-65 T 09-03-2017 IPR023214 HAD-like domain UA74_RS25335 14b7d730bd3fe73c1713850ebd5e7a78 327 Pfam PF13409 Glutathione S-transferase, N-terminal domain 49 141 8.6E-12 T 09-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 UA74_RS25335 14b7d730bd3fe73c1713850ebd5e7a78 327 Gene3D G3DSA:3.40.30.10 23 161 8.9E-13 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS25335 14b7d730bd3fe73c1713850ebd5e7a78 327 SUPERFAMILY SSF52833 25 145 2.61E-7 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS25335 14b7d730bd3fe73c1713850ebd5e7a78 327 SUPERFAMILY SSF47616 162 324 5.85E-33 T 09-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like UA74_RS25335 14b7d730bd3fe73c1713850ebd5e7a78 327 Gene3D G3DSA:1.20.1050.10 162 274 1.4E-22 T 09-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like UA74_RS25335 14b7d730bd3fe73c1713850ebd5e7a78 327 PIRSF PIRSF015753 2 310 2.6E-111 T 09-03-2017 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 UA74_RS25335 14b7d730bd3fe73c1713850ebd5e7a78 327 Pfam PF13410 Glutathione S-transferase, C-terminal domain 190 260 5.6E-11 T 09-03-2017 UA74_RS05340 3b314496c5d3802fbc66f9837307afa4 278 Pfam PF02517 CAAX protease self-immunity 119 210 3.9E-17 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81593 371 525 7.14E-34 T 09-03-2017 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 83 1035 16.481 T 09-03-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 86 355 6.9E-36 T 09-03-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 629 878 5.5E-60 T 09-03-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF08335 GlnD PII-uridylyltransferase 378 524 1.3E-32 T 09-03-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF08335 GlnD PII-uridylyltransferase 901 1043 3.2E-23 T 09-03-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Gene3D G3DSA:3.30.460.10 712 887 4.7E-53 T 09-03-2017 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Gene3D G3DSA:3.30.460.10 185 364 2.2E-46 T 09-03-2017 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81593 894 1045 2.04E-36 T 09-03-2017 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81301 72 364 1.01E-51 T 09-03-2017 UA74_RS25275 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81301 601 887 3.01E-64 T 09-03-2017 UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 Gene3D G3DSA:1.20.200.10 102 451 4.8E-79 T 09-03-2017 UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 Pfam PF00206 Lyase 42 304 6.5E-20 T 09-03-2017 IPR022761 Fumarate lyase, N-terminal UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 SMART SM00998 369 455 1.3E-20 T 09-03-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 1.2E-9 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 1.2E-9 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 1.2E-9 T 09-03-2017 IPR000362 Fumarate lyase family UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 09-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 Gene3D G3DSA:1.10.275.10 13 101 8.4E-20 T 09-03-2017 IPR024083 Fumarase/histidase, N-terminal UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 452 5.3E-123 T 09-03-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 453 1.4E-11 T 09-03-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_RS29465 d7563a29a557a0e10d8685bc11b6dcb5 477 SUPERFAMILY SSF48557 10 456 1.52E-78 T 09-03-2017 IPR008948 L-Aspartase-like GO:0003824 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 SUPERFAMILY SSF48264 4 453 3.27E-112 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 Pfam PF00067 Cytochrome P450 8 431 1.5E-86 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 Gene3D G3DSA:1.10.630.10 5 453 8.7E-119 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 392 402 2.8E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 255 272 2.8E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 357 381 2.8E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 275 301 2.8E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 402 425 2.8E-20 T 09-03-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 393 402 9.3E-14 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 318 329 9.3E-14 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 266 283 9.3E-14 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS28820 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 402 413 9.3E-14 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS24205 73bf37a2866c76cf2bc5bccee0191cc0 417 Pfam PF01566 Natural resistance-associated macrophage protein 48 392 6.7E-73 T 09-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 UA74_RS07940 3940d512230e630a55f70c66dc6a8f70 111 SUPERFAMILY SSF46955 26 98 2.84E-12 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS07940 3940d512230e630a55f70c66dc6a8f70 111 Gene3D G3DSA:1.10.1660.10 26 101 2.3E-14 T 09-03-2017 UA74_RS07940 3940d512230e630a55f70c66dc6a8f70 111 Pfam PF13411 MerR HTH family regulatory protein 26 88 2.7E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS07940 3940d512230e630a55f70c66dc6a8f70 111 SMART SM00422 26 94 1.3E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF13191 AAA ATPase domain 267 397 5.3E-8 T 09-03-2017 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SUPERFAMILY SSF50978 1074 1185 4.03E-39 T 09-03-2017 IPR017986 WD40-repeat-containing domain GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SUPERFAMILY SSF50978 824 1039 4.03E-39 T 09-03-2017 IPR017986 WD40-repeat-containing domain GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1151 1200 290.0 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1255 1294 0.043 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 991 1029 7.0 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1068 1107 0.0024 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1340 1382 13.0 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1297 1337 0.0014 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 899 937 6.9E-4 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 816 856 0.038 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:3.40.50.300 262 320 6.3E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF00400 WD domain, G-beta repeat 914 936 0.17 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF00400 WD domain, G-beta repeat 1086 1107 0.034 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF00400 WD domain, G-beta repeat 1299 1337 0.14 T 09-03-2017 IPR001680 WD40 repeat GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 SUPERFAMILY SSF82171 1056 1393 5.49E-33 T 09-03-2017 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:2.130.10.10 964 1173 6.2E-24 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1324 1338 - T 09-03-2017 IPR019775 WD40 repeat, conserved site UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:2.130.10.10 787 949 4.6E-29 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS06855 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:2.130.10.10 1174 1384 1.9E-27 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS10170 4faa49ace235a770dca18db34b9666ec 1132 Gene3D G3DSA:3.60.21.10 779 1006 4.4E-22 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS10170 4faa49ace235a770dca18db34b9666ec 1132 Pfam PF09992 Phosphodiester glycosidase 258 411 9.8E-30 T 09-03-2017 IPR018711 Phosphodiester glycosidase UA74_RS10170 4faa49ace235a770dca18db34b9666ec 1132 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 574 585 - T 09-03-2017 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 UA74_RS10170 4faa49ace235a770dca18db34b9666ec 1132 SUPERFAMILY SSF56300 783 999 1.54E-26 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS10170 4faa49ace235a770dca18db34b9666ec 1132 Pfam PF00149 Calcineurin-like phosphoesterase 783 961 1.8E-12 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS15265 c13a47c2d65ccfa258e8e998183f935f 318 Gene3D G3DSA:1.10.150.130 25 108 2.4E-5 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS15265 c13a47c2d65ccfa258e8e998183f935f 318 Pfam PF00589 Phage integrase family 142 298 1.0E-15 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15265 c13a47c2d65ccfa258e8e998183f935f 318 SUPERFAMILY SSF56349 21 299 2.03E-28 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS15265 c13a47c2d65ccfa258e8e998183f935f 318 Gene3D G3DSA:1.10.443.10 134 304 1.9E-25 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS16980 c1247e358013ab603ab68121bb8471d5 542 Pfam PF12831 FAD dependent oxidoreductase 12 514 6.0E-112 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16980 c1247e358013ab603ab68121bb8471d5 542 Gene3D G3DSA:3.50.50.60 429 513 2.1E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16980 c1247e358013ab603ab68121bb8471d5 542 Gene3D G3DSA:3.50.50.60 7 245 2.1E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16980 c1247e358013ab603ab68121bb8471d5 542 SUPERFAMILY SSF51905 2 267 2.64E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS29540 6f9c7452c28d8d9da2c774650225d0af 542 Pfam PF00999 Sodium/hydrogen exchanger family 5 408 2.1E-52 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UA74_RS29540 6f9c7452c28d8d9da2c774650225d0af 542 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 535 2.9E-90 T 09-03-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 UA74_RS27905 24786af8ebcebadcb1202f04e90cd2a9 73 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 6 70 2.0E-8 T 09-03-2017 IPR026496 Putative ATP-grasp target RiPP UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 SUPERFAMILY SSF52540 408 779 5.12E-85 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 SUPERFAMILY SSF52540 4 327 5.12E-85 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 293 2.8E-35 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Pfam PF13361 UvrD-like helicase C-terminal domain 674 761 1.6E-9 T 09-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Gene3D G3DSA:3.40.50.300 401 496 1.4E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Gene3D G3DSA:3.40.50.300 676 779 1.4E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Pfam PF12705 PD-(D/E)XK nuclease superfamily 862 1110 3.8E-36 T 09-03-2017 UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Gene3D G3DSA:3.40.50.300 188 293 2.7E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Gene3D G3DSA:3.40.50.300 3 144 2.7E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04805 2685773f25764bb569c8bff28029383d 1120 Gene3D G3DSA:1.10.486.10 537 657 1.1E-4 T 09-03-2017 UA74_RS23540 a4606b4d1a478ca6dd3568cd4b4ec603 117 Gene3D G3DSA:3.30.750.24 12 98 2.2E-27 T 09-03-2017 IPR002645 STAS domain UA74_RS23540 a4606b4d1a478ca6dd3568cd4b4ec603 117 SUPERFAMILY SSF52091 12 100 1.39E-21 T 09-03-2017 IPR002645 STAS domain UA74_RS23540 a4606b4d1a478ca6dd3568cd4b4ec603 117 Pfam PF13466 STAS domain 14 94 5.3E-19 T 09-03-2017 IPR002645 STAS domain UA74_RS23540 a4606b4d1a478ca6dd3568cd4b4ec603 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 11 100 1.4E-23 T 09-03-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UA74_RS10255 e3d0086f461c9819564cced4adeb3756 287 Gene3D G3DSA:3.90.850.10 67 281 1.4E-82 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS10255 e3d0086f461c9819564cced4adeb3756 287 SUPERFAMILY SSF56529 64 281 1.2E-72 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS10255 e3d0086f461c9819564cced4adeb3756 287 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 279 1.5E-66 T 09-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 UA74_RS09795 8b2955be6ed03b67bff7f9740d70a545 94 Pfam PF02325 YGGT family 10 91 1.5E-13 T 09-03-2017 IPR003425 CCB3/YggT GO:0016020 UA74_RS23865 9b2d6a1929828631735cdebcc45f6482 295 SUPERFAMILY SSF51735 2 294 1.81E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23865 9b2d6a1929828631735cdebcc45f6482 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 238 2.6E-21 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS23865 9b2d6a1929828631735cdebcc45f6482 295 Gene3D G3DSA:3.40.50.720 2 192 7.4E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29135 17ac9521fc29e26887582fe5d4837b09 193 Gene3D G3DSA:3.90.79.10 5 185 2.8E-38 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS29135 17ac9521fc29e26887582fe5d4837b09 193 SUPERFAMILY SSF55811 13 183 5.69E-35 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS29135 17ac9521fc29e26887582fe5d4837b09 193 ProSitePatterns PS00893 Nudix box signature. 84 105 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS29135 17ac9521fc29e26887582fe5d4837b09 193 Pfam PF00293 NUDIX domain 52 160 2.2E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS25480 0dc069d81896f38c603960606e677505 306 SMART SM00530 6 83 4.5E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS25480 0dc069d81896f38c603960606e677505 306 Pfam PF13560 Helix-turn-helix domain 33 86 4.1E-15 T 09-03-2017 UA74_RS25480 0dc069d81896f38c603960606e677505 306 Gene3D G3DSA:1.10.260.40 32 82 5.5E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25480 0dc069d81896f38c603960606e677505 306 SUPERFAMILY SSF47413 32 81 1.16E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25580 8446b681accb7467a5bf96806b55c695 402 Pfam PF13556 PucR C-terminal helix-turn-helix domain 334 392 2.2E-22 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain UA74_RS06480 8e21f7a76a596a63a2194d319396f8fe 437 Pfam PF00534 Glycosyl transferases group 1 213 374 1.7E-39 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS06480 8e21f7a76a596a63a2194d319396f8fe 437 Gene3D G3DSA:3.40.50.2000 179 374 1.8E-44 T 09-03-2017 UA74_RS06480 8e21f7a76a596a63a2194d319396f8fe 437 SUPERFAMILY SSF53756 1 394 4.19E-95 T 09-03-2017 UA74_RS06480 8e21f7a76a596a63a2194d319396f8fe 437 Gene3D G3DSA:3.40.50.2000 13 154 1.5E-7 T 09-03-2017 UA74_RS06480 8e21f7a76a596a63a2194d319396f8fe 437 Pfam PF13439 Glycosyltransferase Family 4 15 197 1.0E-31 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 SUPERFAMILY SSF53098 20 203 1.07E-54 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 SUPERFAMILY SSF82771 226 304 9.29E-14 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 SMART SM00465 226 307 1.7E-10 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 SUPERFAMILY SSF46600 402 444 7.32E-6 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 SMART SM00479 25 193 2.7E-47 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 Gene3D G3DSA:3.30.420.10 19 199 1.1E-56 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 Pfam PF02151 UvrB/uvrC motif 413 443 5.8E-5 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 21 188 2.8E-31 T 09-03-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 Gene3D G3DSA:4.10.860.10 392 445 3.7E-7 T 09-03-2017 IPR001943 UVR domain GO:0005515 UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 Pfam PF00929 Exonuclease 27 184 5.6E-34 T 09-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_RS25025 5edc59218b2f186aeb3a1cb22005deec 573 Pfam PF01541 GIY-YIG catalytic domain 228 302 6.6E-5 T 09-03-2017 IPR000305 GIY-YIG nuclease superfamily UA74_RS28055 51d72b643ec18665137aa6914db5ff31 376 SMART SM01240 15 376 1.3E-16 T 09-03-2017 UA74_RS28055 51d72b643ec18665137aa6914db5ff31 376 SUPERFAMILY SSF51412 10 78 6.93E-63 T 09-03-2017 UA74_RS28055 51d72b643ec18665137aa6914db5ff31 376 SUPERFAMILY SSF51412 119 375 6.93E-63 T 09-03-2017 UA74_RS28055 51d72b643ec18665137aa6914db5ff31 376 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 18 305 1.7E-35 T 09-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 UA74_RS28055 51d72b643ec18665137aa6914db5ff31 376 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 374 7.0E-170 T 09-03-2017 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 UA74_RS28055 51d72b643ec18665137aa6914db5ff31 376 Gene3D G3DSA:3.20.20.70 12 375 3.4E-69 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS16880 4dd6ad5a807ca976ecfefb50b6f20e3c 147 SMART SM00347 26 125 2.0E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS16880 4dd6ad5a807ca976ecfefb50b6f20e3c 147 Gene3D G3DSA:1.10.10.10 9 137 2.0E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16880 4dd6ad5a807ca976ecfefb50b6f20e3c 147 Pfam PF01047 MarR family 33 91 2.7E-8 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS16880 4dd6ad5a807ca976ecfefb50b6f20e3c 147 SUPERFAMILY SSF46785 12 140 2.25E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07470 31501c947935e7108beac61229b18b1f 403 SUPERFAMILY SSF47413 5 70 3.49E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS07470 31501c947935e7108beac61229b18b1f 403 SMART SM00530 11 67 7.8E-8 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS07470 31501c947935e7108beac61229b18b1f 403 Pfam PF13560 Helix-turn-helix domain 8 66 2.6E-11 T 09-03-2017 UA74_RS07470 31501c947935e7108beac61229b18b1f 403 Gene3D G3DSA:1.10.260.40 8 83 1.7E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 Gene3D G3DSA:1.10.630.10 395 469 1.5E-18 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 Gene3D G3DSA:1.10.630.10 41 337 2.3E-51 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 SUPERFAMILY SSF48264 42 337 1.44E-41 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 165 180 6.8E-10 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 307 334 6.8E-10 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 290 301 6.8E-10 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 148 164 6.8E-10 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 SUPERFAMILY SSF48264 396 471 7.33E-16 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 414 423 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 Pfam PF00067 Cytochrome P450 397 438 2.1E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09245 c9eac44adcbd3535bc436e28198859dc 475 Pfam PF00067 Cytochrome P450 289 337 2.0E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS15225 733b91e34863d8a3d7c2c8788a2de684 292 SMART SM00422 11 80 2.3E-18 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15225 733b91e34863d8a3d7c2c8788a2de684 292 Gene3D G3DSA:1.10.1660.10 12 120 1.2E-25 T 09-03-2017 UA74_RS15225 733b91e34863d8a3d7c2c8788a2de684 292 SUPERFAMILY SSF46955 12 121 2.23E-22 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS15225 733b91e34863d8a3d7c2c8788a2de684 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 2.5E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15225 733b91e34863d8a3d7c2c8788a2de684 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 2.5E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15225 733b91e34863d8a3d7c2c8788a2de684 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 2.5E-6 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15225 733b91e34863d8a3d7c2c8788a2de684 292 Pfam PF00376 MerR family regulatory protein 12 49 1.2E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS04895 c01a31f5b89c126923f550f6647562a4 196 Pfam PF00583 Acetyltransferase (GNAT) family 111 170 2.1E-7 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS04895 c01a31f5b89c126923f550f6647562a4 196 Gene3D G3DSA:3.40.630.30 16 189 1.3E-15 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS04895 c01a31f5b89c126923f550f6647562a4 196 SUPERFAMILY SSF55729 13 73 1.92E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS04895 c01a31f5b89c126923f550f6647562a4 196 SUPERFAMILY SSF55729 106 192 1.92E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS20575 8209a535d1236805cfb249398cb7bf11 329 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 311 2.0E-78 T 09-03-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 UA74_RS20575 8209a535d1236805cfb249398cb7bf11 329 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 285 5.5E-64 T 09-03-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 UA74_RS20575 8209a535d1236805cfb249398cb7bf11 329 PIRSF PIRSF006470 1 326 3.7E-77 T 09-03-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 Pfam PF00561 alpha/beta hydrolase fold 95 252 4.1E-18 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 SUPERFAMILY SSF53474 406 500 6.95E-23 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 SUPERFAMILY SSF53474 199 253 6.95E-23 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 SUPERFAMILY SSF53474 94 152 6.95E-23 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 Gene3D G3DSA:3.40.50.1820 197 326 1.3E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 Gene3D G3DSA:3.40.50.1820 60 150 1.3E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 Gene3D G3DSA:3.40.50.1820 396 515 1.3E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02725 346c5b78c9ac495d47185fadac93ae46 533 Pfam PF08386 TAP-like protein 428 527 7.9E-24 T 09-03-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal UA74_RS07190 d12fbceb392a944cdfd710be2f3b4773 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 109 5.9E-22 T 09-03-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07190 d12fbceb392a944cdfd710be2f3b4773 121 SUPERFAMILY SSF51344 4 84 3.79E-20 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07190 d12fbceb392a944cdfd710be2f3b4773 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 84 5.0E-22 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07190 d12fbceb392a944cdfd710be2f3b4773 121 Gene3D G3DSA:2.60.15.10 3 89 1.3E-23 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07190 d12fbceb392a944cdfd710be2f3b4773 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 6.9E-25 T 09-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS07190 d12fbceb392a944cdfd710be2f3b4773 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 17.306 T 09-03-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 UA74_RS22695 b0f02db4a7e563312a269c5aa7f45b29 215 Gene3D G3DSA:1.10.357.10 4 213 6.6E-41 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22695 b0f02db4a7e563312a269c5aa7f45b29 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 7.5E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22695 b0f02db4a7e563312a269c5aa7f45b29 215 SUPERFAMILY SSF48498 91 214 7.78E-30 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS22695 b0f02db4a7e563312a269c5aa7f45b29 215 SUPERFAMILY SSF46689 10 81 1.6E-16 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS21460 bffc35284b9689e8e5ecfdaf7e546c8b 660 Gene3D G3DSA:3.40.50.300 485 648 1.7E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21460 bffc35284b9689e8e5ecfdaf7e546c8b 660 Pfam PF00580 UvrD/REP helicase N-terminal domain 373 468 5.9E-10 T 09-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 UA74_RS21460 bffc35284b9689e8e5ecfdaf7e546c8b 660 Gene3D G3DSA:3.40.50.300 211 312 3.4E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21460 bffc35284b9689e8e5ecfdaf7e546c8b 660 Gene3D G3DSA:3.40.50.300 396 484 3.4E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21460 bffc35284b9689e8e5ecfdaf7e546c8b 660 Pfam PF13245 Part of AAA domain 232 262 6.9E-6 T 09-03-2017 UA74_RS21460 bffc35284b9689e8e5ecfdaf7e546c8b 660 SUPERFAMILY SSF52540 206 651 2.33E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30440 4910db704247d00e670c14f5f8e1ba85 229 Pfam PF02527 rRNA small subunit methyltransferase G 23 198 2.6E-50 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_RS30440 4910db704247d00e670c14f5f8e1ba85 229 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 196 5.1E-40 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_RS30440 4910db704247d00e670c14f5f8e1ba85 229 SUPERFAMILY SSF53335 25 179 1.52E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS30440 4910db704247d00e670c14f5f8e1ba85 229 PIRSF PIRSF003078 3 214 2.2E-45 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_RS30440 4910db704247d00e670c14f5f8e1ba85 229 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 13 194 25.046 T 09-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_RS30440 4910db704247d00e670c14f5f8e1ba85 229 Gene3D G3DSA:3.40.50.150 21 219 9.0E-63 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS25965 8b90a9ae2c09049970fc48eb9c52f8bb 293 Gene3D G3DSA:3.40.50.300 2 221 2.2E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25965 8b90a9ae2c09049970fc48eb9c52f8bb 293 Pfam PF00005 ABC transporter 20 157 6.7E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS25965 8b90a9ae2c09049970fc48eb9c52f8bb 293 SUPERFAMILY SSF52540 3 223 1.33E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25965 8b90a9ae2c09049970fc48eb9c52f8bb 293 SMART SM00382 29 205 1.3E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00430 fda9d4b46be671f62a9bcf60ee54ff52 401 SMART SM00387 280 390 7.9E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00430 fda9d4b46be671f62a9bcf60ee54ff52 401 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 288 387 1.2E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00430 fda9d4b46be671f62a9bcf60ee54ff52 401 Pfam PF06580 Histidine kinase 190 266 1.1E-24 T 09-03-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 UA74_RS00430 fda9d4b46be671f62a9bcf60ee54ff52 401 SUPERFAMILY SSF55874 254 387 2.1E-17 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS00430 fda9d4b46be671f62a9bcf60ee54ff52 401 Gene3D G3DSA:3.30.565.10 246 388 1.4E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS06300 0499f61bd2ea51d9e2353fe251c535ab 341 Pfam PF03576 Peptidase family S58 11 329 3.8E-70 T 09-03-2017 IPR005321 Peptidase S58, DmpA UA74_RS06300 0499f61bd2ea51d9e2353fe251c535ab 341 SUPERFAMILY SSF56266 5 335 4.19E-76 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_RS06300 0499f61bd2ea51d9e2353fe251c535ab 341 Gene3D G3DSA:3.60.70.12 6 334 2.2E-92 T 09-03-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_RS13445 258d7832e964cb8c7104c858c57791f0 461 Pfam PF14315 Domain of unknown function (DUF4380) 40 332 6.4E-12 T 09-03-2017 IPR025488 Protein of unknown function DUF4380 UA74_RS12425 67bdb089cd3a8157b1c6b6f04d2560cf 285 PIRSF PIRSF005052 1 285 1.2E-110 T 09-03-2017 IPR005337 RapZ-like family GO:0005524 UA74_RS12425 67bdb089cd3a8157b1c6b6f04d2560cf 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 40.889 T 09-03-2017 IPR005337 RapZ-like family GO:0005524 UA74_RS12425 67bdb089cd3a8157b1c6b6f04d2560cf 285 SUPERFAMILY SSF52540 5 154 2.48E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12425 67bdb089cd3a8157b1c6b6f04d2560cf 285 Gene3D G3DSA:3.40.50.300 5 156 4.6E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12425 67bdb089cd3a8157b1c6b6f04d2560cf 285 Pfam PF03668 P-loop ATPase protein family 1 285 3.7E-109 T 09-03-2017 IPR005337 RapZ-like family GO:0005524 UA74_RS30390 98353e6b52d0635450a636870c9db19f 205 Gene3D G3DSA:1.10.1740.10 5 110 6.4E-32 T 09-03-2017 UA74_RS30390 98353e6b52d0635450a636870c9db19f 205 Pfam PF04542 Sigma-70 region 2 26 93 7.8E-18 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS30390 98353e6b52d0635450a636870c9db19f 205 Gene3D G3DSA:1.10.10.10 114 179 2.2E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS30390 98353e6b52d0635450a636870c9db19f 205 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 3.6E-31 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS30390 98353e6b52d0635450a636870c9db19f 205 SUPERFAMILY SSF88946 6 104 1.51E-29 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS30390 98353e6b52d0635450a636870c9db19f 205 SUPERFAMILY SSF88659 113 178 2.4E-16 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS30390 98353e6b52d0635450a636870c9db19f 205 Pfam PF08281 Sigma-70, region 4 121 173 2.0E-16 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 Gene3D G3DSA:3.90.1170.30 325 416 1.7E-24 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 Gene3D G3DSA:3.40.1030.10 74 323 8.3E-108 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 70 4.2E-17 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 SMART SM00941 341 415 6.9E-23 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 SUPERFAMILY SSF52418 74 323 9.55E-81 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 8 410 3.4E-162 T 09-03-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 Gene3D G3DSA:1.20.970.10 6 71 2.4E-28 T 09-03-2017 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 PIRSF PIRSF000478 4 430 3.8E-149 T 09-03-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 Pfam PF00591 Glycosyl transferase family, a/b domain 81 306 3.5E-32 T 09-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 342 414 5.2E-17 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 SUPERFAMILY SSF47648 6 73 3.92E-20 T 09-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 SUPERFAMILY SSF54680 328 431 7.06E-21 T 09-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS27650 7349c201e19cc52c0802d4056d8637ef 436 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 114 129 - T 09-03-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_RS13425 4e39a3841a182f874cc0dfb7985bdf68 329 Gene3D G3DSA:3.40.50.2300 160 303 6.8E-24 T 09-03-2017 UA74_RS13425 4e39a3841a182f874cc0dfb7985bdf68 329 Gene3D G3DSA:3.40.50.2300 37 159 1.7E-23 T 09-03-2017 UA74_RS13425 4e39a3841a182f874cc0dfb7985bdf68 329 SUPERFAMILY SSF53822 34 309 3.08E-49 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS13425 4e39a3841a182f874cc0dfb7985bdf68 329 Pfam PF13407 Periplasmic binding protein domain 37 297 2.8E-34 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS13630 ec3e2674020e78d997cc24d97bc9393d 253 Pfam PF13458 Periplasmic binding protein 16 223 2.3E-28 T 09-03-2017 IPR028081 Leucine-binding protein domain UA74_RS13630 ec3e2674020e78d997cc24d97bc9393d 253 Gene3D G3DSA:3.40.50.2300 19 173 9.3E-19 T 09-03-2017 UA74_RS13630 ec3e2674020e78d997cc24d97bc9393d 253 SUPERFAMILY SSF53822 18 249 7.06E-27 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS20890 f58fedbe438d5ab6ddffe8c956a22189 204 Pfam PF01810 LysE type translocator 15 202 4.3E-45 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 UA74_RS13800 224df53e706b9ec469635f1d91127cf7 430 SMART SM00387 169 280 6.0E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS13800 224df53e706b9ec469635f1d91127cf7 430 Gene3D G3DSA:3.30.565.10 166 279 6.4E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS13800 224df53e706b9ec469635f1d91127cf7 430 SUPERFAMILY SSF55874 162 279 5.24E-20 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS13800 224df53e706b9ec469635f1d91127cf7 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 173 277 1.3E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS01920 9530e537d47d01778630ca9188e549c1 191 Gene3D G3DSA:3.40.630.30 9 182 4.4E-46 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS01920 9530e537d47d01778630ca9188e549c1 191 SUPERFAMILY SSF55729 10 179 1.77E-41 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS01920 9530e537d47d01778630ca9188e549c1 191 Pfam PF13302 Acetyltransferase (GNAT) domain 18 155 1.3E-20 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS20360 5c5d08cd05381661edce69d4fe8e3018 137 SMART SM00960 10 101 3.1E-20 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS20360 5c5d08cd05381661edce69d4fe8e3018 137 Gene3D G3DSA:3.30.450.30 6 128 1.3E-24 T 09-03-2017 UA74_RS20360 5c5d08cd05381661edce69d4fe8e3018 137 Pfam PF03259 Roadblock/LC7 domain 12 100 9.3E-21 T 09-03-2017 IPR004942 Roadblock/LAMTOR2 domain UA74_RS20360 5c5d08cd05381661edce69d4fe8e3018 137 SUPERFAMILY SSF103196 2 129 1.33E-26 T 09-03-2017 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 SUPERFAMILY SSF161098 34 146 6.45E-6 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 SUPERFAMILY SSF161098 320 442 1.96E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 Gene3D G3DSA:1.10.3720.10 309 443 8.8E-30 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 Gene3D G3DSA:1.10.3720.10 671 735 4.0E-6 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 Gene3D G3DSA:1.10.3720.10 34 154 8.8E-30 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 Gene3D G3DSA:1.10.3720.10 477 643 1.9E-12 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 SUPERFAMILY SSF161098 478 746 9.16E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08295 4719cdf6525dbb6866a563d27257f27b 754 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 321 443 4.0E-10 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS16665 3fd58422ccd57c8fad4fd62d64dec8a8 244 Pfam PF12730 ABC-2 family transporter protein 22 157 2.6E-6 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 UA74_RS15410 718855060ffef4fc229a8c20637039a8 125 Pfam PF03795 YCII-related domain 1 113 9.9E-11 T 09-03-2017 IPR005545 YCII-related UA74_RS15410 718855060ffef4fc229a8c20637039a8 125 Gene3D G3DSA:3.30.70.1060 1 116 1.7E-31 T 09-03-2017 UA74_RS15410 718855060ffef4fc229a8c20637039a8 125 SUPERFAMILY SSF54909 14 114 1.07E-20 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS24320 f61dab20eeb9361858487fd012989fee 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 293 4.3E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24320 f61dab20eeb9361858487fd012989fee 309 Gene3D G3DSA:1.10.3720.10 30 296 9.4E-51 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24320 f61dab20eeb9361858487fd012989fee 309 SUPERFAMILY SSF161098 30 308 1.01E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 Pfam PF13183 4Fe-4S dicluster domain 518 598 8.0E-9 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 Gene3D G3DSA:3.30.465.10 84 239 4.9E-30 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 Gene3D G3DSA:3.30.43.10 8 80 1.2E-19 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 Gene3D G3DSA:1.10.1060.10 460 607 4.2E-12 T 09-03-2017 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 Pfam PF01565 FAD binding domain 30 166 8.7E-40 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 Pfam PF02913 FAD linked oxidases, C-terminal domain 243 479 6.2E-47 T 09-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 SUPERFAMILY SSF46548 514 603 2.04E-8 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 SUPERFAMILY SSF56176 11 167 2.33E-49 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 SUPERFAMILY SSF56176 200 239 2.33E-49 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 SUPERFAMILY SSF55103 243 483 2.13E-51 T 09-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UA74_RS19875 963df9182cbc194adf68c6361faa4505 687 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 584 595 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 SUPERFAMILY SSF53807 40 314 7.36E-68 T 09-03-2017 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 253 271 2.6E-21 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 40 58 2.6E-21 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 71 84 2.6E-21 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 198 219 2.6E-21 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 280 299 2.6E-21 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 84 101 2.6E-21 T 09-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 40 61 5.0E-19 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 293 311 5.0E-19 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 84 103 5.0E-19 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 198 215 5.0E-19 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 249 266 5.0E-19 T 09-03-2017 IPR006129 Adhesin B GO:0007155 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 Gene3D G3DSA:3.40.50.1980 36 190 5.3E-40 T 09-03-2017 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 312 4.9E-69 T 09-03-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UA74_RS19695 b066b60f29620a1618d74606f233c7d3 318 Gene3D G3DSA:3.40.50.1980 191 314 4.8E-33 T 09-03-2017 UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 88 184 1.1E-12 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 Gene3D G3DSA:3.40.50.1000 7 201 2.6E-31 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 Pfam PF13419 Haloacid dehalogenase-like hydrolase 97 183 1.0E-8 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 SUPERFAMILY SSF56784 8 193 4.05E-28 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 8 19 1.9E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 1.9E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 1.9E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS29515 ec9fd6203ae50b4c44fc3eb5e61c50a6 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 1.9E-10 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 SUPERFAMILY SSF48498 83 180 3.18E-8 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 6.4E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 Pfam PF13977 Bacterial transcriptional repressor 84 177 2.3E-6 T 09-03-2017 UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 SUPERFAMILY SSF46689 8 84 6.98E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 Gene3D G3DSA:1.10.357.10 10 181 5.7E-30 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS08135 d0a229b4f6835aeb5f2167b53f79e4fe 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.8E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS16480 86de46694e449865534129486ef20775 416 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 247 386 7.9E-11 T 09-03-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 UA74_RS16480 86de46694e449865534129486ef20775 416 SUPERFAMILY SSF53756 20 411 8.03E-68 T 09-03-2017 UA74_RS16480 86de46694e449865534129486ef20775 416 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 24 407 5.8E-106 T 09-03-2017 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_RS16480 86de46694e449865534129486ef20775 416 Gene3D G3DSA:3.40.50.2000 19 252 1.8E-10 T 09-03-2017 UA74_RS16480 86de46694e449865534129486ef20775 416 Gene3D G3DSA:3.40.50.2000 253 393 1.9E-27 T 09-03-2017 UA74_RS10235 69b3ec74a6a3227876e9e55b48ca7634 331 SUPERFAMILY SSF48576 18 300 7.19E-71 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS10235 69b3ec74a6a3227876e9e55b48ca7634 331 Gene3D G3DSA:1.10.600.10 16 313 2.5E-76 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS10235 69b3ec74a6a3227876e9e55b48ca7634 331 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 170 195 - T 09-03-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 UA74_RS10235 69b3ec74a6a3227876e9e55b48ca7634 331 Pfam PF00494 Squalene/phytoene synthase 29 285 4.3E-59 T 09-03-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 UA74_RS30135 63c795c4b12fee1a19afbba0ebd05c10 188 Gene3D G3DSA:1.10.10.10 1 87 6.5E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS30135 63c795c4b12fee1a19afbba0ebd05c10 188 SUPERFAMILY SSF46785 2 173 1.62E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS30135 63c795c4b12fee1a19afbba0ebd05c10 188 Pfam PF03551 Transcriptional regulator PadR-like family 6 85 6.5E-19 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS17120 b39997b50c92dd77dbaba7f063ef6368 245 Gene3D G3DSA:3.90.79.10 9 147 3.8E-40 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS17120 b39997b50c92dd77dbaba7f063ef6368 245 Gene3D G3DSA:1.10.10.10 150 222 1.9E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17120 b39997b50c92dd77dbaba7f063ef6368 245 SUPERFAMILY SSF55811 5 154 9.07E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS17120 b39997b50c92dd77dbaba7f063ef6368 245 SUPERFAMILY SSF46785 158 229 9.11E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17120 b39997b50c92dd77dbaba7f063ef6368 245 Pfam PF00293 NUDIX domain 18 142 2.0E-15 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS29700 5b52db5c7c0c574208d1da14fd4ba053 221 Pfam PF00005 ABC transporter 18 165 1.6E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS29700 5b52db5c7c0c574208d1da14fd4ba053 221 SMART SM00382 26 214 1.4E-21 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS29700 5b52db5c7c0c574208d1da14fd4ba053 221 SUPERFAMILY SSF52540 4 216 3.31E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29700 5b52db5c7c0c574208d1da14fd4ba053 221 Gene3D G3DSA:3.40.50.300 5 215 9.0E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08470 f4a870c223891088d6270ba481554f62 307 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 10 305 37.483 T 09-03-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 UA74_RS08470 f4a870c223891088d6270ba481554f62 307 Pfam PF04227 Indigoidine synthase A like protein 11 302 1.5E-111 T 09-03-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 UA74_RS08470 f4a870c223891088d6270ba481554f62 307 SUPERFAMILY SSF110581 5 304 1.96E-94 T 09-03-2017 UA74_RS13250 1e1749666bc6875cda7bec6e50d2a605 196 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 7 165 8.9E-58 T 09-03-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain UA74_RS13250 1e1749666bc6875cda7bec6e50d2a605 196 Pfam PF13298 DNA polymerase Ligase (LigD) 36 147 6.0E-39 T 09-03-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain UA74_RS21925 9b7c7f8b5dafe96798080a744f2ea98b 302 Pfam PF14100 Methane oxygenase PmoA 14 295 2.7E-80 T 09-03-2017 IPR029475 Methane oxygenase PmoA UA74_RS28985 909450231724a8d5dbd82797d55a286d 389 SUPERFAMILY SSF53335 121 217 6.58E-10 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28985 909450231724a8d5dbd82797d55a286d 389 Pfam PF08484 C-methyltransferase C-terminal domain 213 363 2.0E-25 T 09-03-2017 IPR013691 C-methyltransferase UA74_RS28985 909450231724a8d5dbd82797d55a286d 389 Gene3D G3DSA:3.40.50.150 124 222 4.1E-7 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28985 909450231724a8d5dbd82797d55a286d 389 Pfam PF08421 Putative zinc binding domain 9 61 8.7E-13 T 09-03-2017 IPR013630 Methyltransferase putative zinc binding domain UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 525 3.7E-38 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 SUPERFAMILY SSF52518 357 557 6.66E-58 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 Gene3D G3DSA:3.40.50.970 352 550 8.6E-57 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 SUPERFAMILY SSF52467 181 351 8.0E-43 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 Gene3D G3DSA:3.40.50.1220 184 338 5.8E-42 T 09-03-2017 IPR029035 DHS-like NAD/FAD-binding domain UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 1.3E-39 T 09-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 317 4.3E-31 T 09-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 SUPERFAMILY SSF52518 2 173 1.16E-40 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 09-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UA74_RS19715 0c484ced6e3d0cbee40911dff1c16d38 577 Gene3D G3DSA:3.40.50.970 3 173 5.9E-48 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS24395 1539c04bd873c2137c50e363d0d25aed 302 Gene3D G3DSA:3.40.50.300 3 229 2.1E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24395 1539c04bd873c2137c50e363d0d25aed 302 SMART SM00382 28 205 2.0E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS24395 1539c04bd873c2137c50e363d0d25aed 302 SUPERFAMILY SSF52540 3 236 3.25E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24395 1539c04bd873c2137c50e363d0d25aed 302 Pfam PF00005 ABC transporter 20 157 1.8E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS24395 1539c04bd873c2137c50e363d0d25aed 302 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS27930 c83ae10e70374287cf5fd271cd1f8788 435 Gene3D G3DSA:3.40.1140.10 53 124 7.4E-10 T 09-03-2017 UA74_RS27930 c83ae10e70374287cf5fd271cd1f8788 435 Gene3D G3DSA:3.40.1140.10 297 382 7.4E-10 T 09-03-2017 UA74_RS27930 c83ae10e70374287cf5fd271cd1f8788 435 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 42 143 8.7E-18 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS27930 c83ae10e70374287cf5fd271cd1f8788 435 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 293 366 5.7E-15 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS27930 c83ae10e70374287cf5fd271cd1f8788 435 SUPERFAMILY SSF52540 42 159 1.35E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27930 c83ae10e70374287cf5fd271cd1f8788 435 SUPERFAMILY SSF52540 273 370 1.35E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27930 c83ae10e70374287cf5fd271cd1f8788 435 Gene3D G3DSA:3.40.50.300 1 52 2.5E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08385 33fb5e2221bd05f6b5a3c0968f0380e8 420 Gene3D G3DSA:3.40.50.1100 204 402 2.8E-37 T 09-03-2017 UA74_RS08385 33fb5e2221bd05f6b5a3c0968f0380e8 420 SUPERFAMILY SSF53686 17 406 1.44E-84 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS08385 33fb5e2221bd05f6b5a3c0968f0380e8 420 TIGRFAM TIGR00260 thrC: threonine synthase 66 394 1.5E-84 T 09-03-2017 IPR004450 Threonine synthase-like UA74_RS08385 33fb5e2221bd05f6b5a3c0968f0380e8 420 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 87 388 1.4E-65 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS08385 33fb5e2221bd05f6b5a3c0968f0380e8 420 Gene3D G3DSA:3.40.50.1100 120 203 1.4E-29 T 09-03-2017 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 357 4.8E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 SUPERFAMILY SSF55874 347 518 7.33E-41 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 Pfam PF00672 HAMP domain 211 279 4.1E-15 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 SMART SM00304 230 282 2.8E-15 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 453 1.6E-11 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 467 1.6E-11 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 511 1.6E-11 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 492 1.6E-11 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 SMART SM00387 403 514 1.0E-29 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 404 512 6.8E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 SUPERFAMILY SSF47384 273 357 2.75E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 SUPERFAMILY SSF158472 230 281 3.27E-10 T 09-03-2017 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 Gene3D G3DSA:1.10.287.130 282 353 2.1E-14 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 SMART SM00388 290 357 2.4E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS26740 6bb9c94ebd515ac6c18feb3beb1047d1 654 Gene3D G3DSA:3.30.565.10 360 514 2.3E-35 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03115 868521480f6c4858e4b51542b043c605 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03115 868521480f6c4858e4b51542b043c605 37 SUPERFAMILY SSF57840 2 37 2.35E-15 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03115 868521480f6c4858e4b51542b043c605 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 4.6E-19 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03115 868521480f6c4858e4b51542b043c605 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.47 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03115 868521480f6c4858e4b51542b043c605 37 Pfam PF00444 Ribosomal protein L36 2 37 2.3E-16 T 09-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03115 868521480f6c4858e4b51542b043c605 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 4.0E-8 T 09-03-2017 UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 SUPERFAMILY SSF51011 328 410 3.78E-7 T 09-03-2017 UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 PRINTS PR00740 Glycosyl hydrolase family 27 signature 281 302 7.7E-7 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 PRINTS PR00740 Glycosyl hydrolase family 27 signature 28 43 7.7E-7 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 PRINTS PR00740 Glycosyl hydrolase family 27 signature 181 199 7.7E-7 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 SUPERFAMILY SSF51445 1 105 4.21E-62 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 SUPERFAMILY SSF51445 140 325 4.21E-62 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 Gene3D G3DSA:3.20.20.70 1 319 3.8E-96 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 Pfam PF16499 Alpha galactosidase A 146 346 4.4E-22 T 09-03-2017 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS20695 828cc6852c65fd3645e0c83792dfd8df 414 Gene3D G3DSA:2.60.40.1180 320 411 5.6E-13 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 Gene3D G3DSA:1.10.10.10 106 163 7.8E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 Gene3D G3DSA:1.10.1740.10 5 88 1.1E-14 T 09-03-2017 UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 163 8.1E-21 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 Gene3D G3DSA:3.10.450.50 169 290 1.0E-14 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 Pfam PF04542 Sigma-70 region 2 8 73 2.7E-14 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 Pfam PF08281 Sigma-70, region 4 108 159 2.4E-16 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 SUPERFAMILY SSF88946 5 88 5.49E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 SUPERFAMILY SSF88659 84 164 6.35E-14 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07040 e37a3b95c7990bf792dff6782f586695 310 SUPERFAMILY SSF54427 172 291 5.12E-16 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 SUPERFAMILY SSF51294 2893 3033 9.29E-18 T 09-03-2017 IPR028992 Hedgehog/Intein (Hint) domain UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF07591 Pretoxin HINT domain 2902 3035 5.4E-17 T 09-03-2017 UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.170.16.10 2890 3041 4.4E-26 T 09-03-2017 IPR028992 Hedgehog/Intein (Hint) domain UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2572 2651 1.1E-17 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1029 1186 2.0E-15 T 09-03-2017 UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.60.120.200 1023 1196 6.8E-19 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 1874 1908 1.5E-4 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2406 2438 1.8E-5 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 1926 1959 2.4E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2254 2289 6.3E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 1476 1506 2.7E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2335 2373 2.5E-5 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2022 2058 1.1E-7 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2112 2145 3.9E-6 T 09-03-2017 IPR031325 RHS repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 SUPERFAMILY SSF49899 1023 1200 1.58E-20 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1476 1507 2.5E-4 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2064 2098 5.4E-4 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2022 2060 1.8E-5 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1874 1900 1.9E-4 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1926 1959 1.3E-6 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2406 2436 5.6E-6 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2274 2311 5.6E-4 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2112 2143 1.3E-5 T 09-03-2017 IPR006530 YD repeat UA74_RS06015 aecb34adc8cef397ff1c755905a93abf 3149 SMART SM00306 2890 2992 3.4E-12 T 09-03-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 8.5E-18 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 Gene3D G3DSA:1.10.357.10 80 207 6.8E-34 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.0E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.0E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 SUPERFAMILY SSF46689 9 79 3.34E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 Gene3D G3DSA:1.10.10.60 10 67 1.2E-21 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 151 205 2.1E-14 T 09-03-2017 UA74_RS15235 666fe3e8a40f8dc38a371d98d9ed0935 217 SUPERFAMILY SSF48498 82 206 7.71E-10 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS21560 5f0589b7d29822290a2b7372ef7d1e4d 334 SUPERFAMILY SSF53474 125 217 1.76E-7 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21560 5f0589b7d29822290a2b7372ef7d1e4d 334 Gene3D G3DSA:3.40.50.1820 162 251 4.7E-4 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21560 5f0589b7d29822290a2b7372ef7d1e4d 334 Pfam PF06259 Alpha/beta hydrolase 67 240 5.9E-44 T 09-03-2017 IPR010427 Protein of unknown function DUF1023 UA74_RS08300 b61151a4e33899c0aec26b56fee56db6 469 SUPERFAMILY SSF48452 280 408 1.98E-9 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS08300 b61151a4e33899c0aec26b56fee56db6 469 Gene3D G3DSA:1.25.40.10 278 343 3.6E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS08300 b61151a4e33899c0aec26b56fee56db6 469 Gene3D G3DSA:1.25.40.10 344 402 4.0E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS04780 fd1d6f11d01cfd80590fe501d5613812 389 Pfam PF00899 ThiF family 24 255 2.0E-61 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UA74_RS04780 fd1d6f11d01cfd80590fe501d5613812 389 Gene3D G3DSA:3.40.50.720 15 256 1.8E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS04780 fd1d6f11d01cfd80590fe501d5613812 389 Pfam PF00581 Rhodanese-like domain 287 380 4.1E-14 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS04780 fd1d6f11d01cfd80590fe501d5613812 389 SMART SM00450 287 384 1.1E-28 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS04780 fd1d6f11d01cfd80590fe501d5613812 389 Gene3D G3DSA:3.40.250.10 282 384 6.4E-28 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS04780 fd1d6f11d01cfd80590fe501d5613812 389 SUPERFAMILY SSF69572 10 356 1.57E-97 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UA74_RS18060 51001a1543dd25b9b968c27a5132cf9d 286 Gene3D G3DSA:2.115.10.10 131 265 1.4E-17 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS18060 51001a1543dd25b9b968c27a5132cf9d 286 Pfam PF14517 Tachylectin 45 247 6.9E-21 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS18060 51001a1543dd25b9b968c27a5132cf9d 286 SUPERFAMILY SSF50934 124 250 9.42E-15 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS05345 ac1409e12c64bfe46841ad8b1267382a 214 SUPERFAMILY SSF51735 3 210 2.12E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05345 ac1409e12c64bfe46841ad8b1267382a 214 Pfam PF13460 NAD(P)H-binding 8 201 4.9E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05345 ac1409e12c64bfe46841ad8b1267382a 214 Gene3D G3DSA:3.40.50.720 3 212 7.8E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14190 8d11225ad6aeb82d076f3c2338ff78b6 207 Gene3D G3DSA:1.10.10.60 17 67 5.4E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14190 8d11225ad6aeb82d076f3c2338ff78b6 207 SUPERFAMILY SSF46689 19 71 4.58E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14190 8d11225ad6aeb82d076f3c2338ff78b6 207 Gene3D G3DSA:1.10.357.10 68 200 3.3E-19 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS14190 8d11225ad6aeb82d076f3c2338ff78b6 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 69 1.7E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS19360 9b17561a1e0d48acc13b1ec7b4534fc0 840 Pfam PF03176 MMPL family 523 789 2.2E-32 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 UA74_RS19360 9b17561a1e0d48acc13b1ec7b4534fc0 840 Pfam PF03176 MMPL family 181 438 1.2E-38 T 09-03-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 UA74_RS19360 9b17561a1e0d48acc13b1ec7b4534fc0 840 SUPERFAMILY SSF82866 547 788 2.75E-28 T 09-03-2017 UA74_RS19360 9b17561a1e0d48acc13b1ec7b4534fc0 840 SUPERFAMILY SSF82866 238 430 4.19E-25 T 09-03-2017 UA74_RS19360 9b17561a1e0d48acc13b1ec7b4534fc0 840 Gene3D G3DSA:1.20.1640.10 238 431 8.3E-23 T 09-03-2017 UA74_RS19360 9b17561a1e0d48acc13b1ec7b4534fc0 840 Gene3D G3DSA:1.20.1640.10 591 794 4.6E-29 T 09-03-2017 UA74_RS15650 725df0bb693207a6b7c68b8a2df773ef 256 Gene3D G3DSA:3.40.50.360 1 233 3.6E-69 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS15650 725df0bb693207a6b7c68b8a2df773ef 256 Pfam PF02525 Flavodoxin-like fold 1 214 1.9E-54 T 09-03-2017 IPR003680 Flavodoxin-like fold UA74_RS15650 725df0bb693207a6b7c68b8a2df773ef 256 SUPERFAMILY SSF52218 1 235 2.79E-66 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 Gene3D G3DSA:3.40.50.980 198 290 2.4E-26 T 09-03-2017 UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 Gene3D G3DSA:3.40.50.980 340 403 2.4E-26 T 09-03-2017 UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 Gene3D G3DSA:2.30.38.10 404 466 1.8E-19 T 09-03-2017 UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 Gene3D G3DSA:3.30.300.30 470 589 8.8E-4 T 09-03-2017 UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 Gene3D G3DSA:3.40.50.980 42 197 1.4E-31 T 09-03-2017 UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 Pfam PF00501 AMP-binding enzyme 24 472 2.6E-95 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 SUPERFAMILY SSF56801 17 295 2.35E-111 T 09-03-2017 UA74_RS25000 d274ba1b8957215dafbed221b7087d3e 603 SUPERFAMILY SSF56801 343 593 2.35E-111 T 09-03-2017 UA74_RS14320 8b70fc0a421d83c5e5c7a8d822ca39eb 424 SUPERFAMILY SSF103473 33 415 3.79E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14320 8b70fc0a421d83c5e5c7a8d822ca39eb 424 Pfam PF07690 Major Facilitator Superfamily 41 359 7.1E-18 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS14320 8b70fc0a421d83c5e5c7a8d822ca39eb 424 Gene3D G3DSA:1.20.1250.20 36 214 2.2E-11 T 09-03-2017 UA74_RS14320 8b70fc0a421d83c5e5c7a8d822ca39eb 424 Gene3D G3DSA:1.20.1250.20 241 422 3.0E-16 T 09-03-2017 UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 Pfam PF00106 short chain dehydrogenase 1 191 2.1E-38 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.9E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.9E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 2.9E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.9E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 5.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 5.7E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 Gene3D G3DSA:3.40.50.720 1 226 2.8E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15510 fa49c4ef58fe75d8ed950920dc18cb51 233 SUPERFAMILY SSF51735 1 217 6.22E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17440 6d87fb5281c15c8d1e092d0800bd1c14 66 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 2.7E-7 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS17440 6d87fb5281c15c8d1e092d0800bd1c14 66 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.7E-7 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS17440 6d87fb5281c15c8d1e092d0800bd1c14 66 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.7E-7 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS17440 6d87fb5281c15c8d1e092d0800bd1c14 66 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 1.6E-13 T 09-03-2017 UA74_RS17440 6d87fb5281c15c8d1e092d0800bd1c14 66 SUPERFAMILY SSF54862 2 61 4.41E-14 T 09-03-2017 UA74_RS17440 6d87fb5281c15c8d1e092d0800bd1c14 66 Gene3D G3DSA:3.30.70.20 1 63 6.0E-18 T 09-03-2017 UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 Pfam PF00106 short chain dehydrogenase 3 200 1.0E-45 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 SUPERFAMILY SSF51735 3 233 4.08E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.6E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.6E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 Gene3D G3DSA:3.40.50.720 1 232 1.8E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.5E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.5E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.5E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.5E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24420 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.5E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS08970 dde061e2facda130a601f37a06f34416 575 SUPERFAMILY SSF53850 69 550 9.45E-103 T 09-03-2017 UA74_RS08970 dde061e2facda130a601f37a06f34416 575 Gene3D G3DSA:3.10.105.10 318 531 1.5E-37 T 09-03-2017 UA74_RS08970 dde061e2facda130a601f37a06f34416 575 Gene3D G3DSA:3.90.76.10 75 217 2.9E-33 T 09-03-2017 UA74_RS08970 dde061e2facda130a601f37a06f34416 575 Gene3D G3DSA:3.40.190.10 218 317 9.1E-22 T 09-03-2017 UA74_RS08970 dde061e2facda130a601f37a06f34416 575 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 106 468 9.4E-74 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS08970 dde061e2facda130a601f37a06f34416 575 PIRSF PIRSF002741 27 554 4.2E-83 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS04370 0795bcd14f491ae1d77420c5f10a43a4 334 SMART SM00382 54 237 1.1E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04370 0795bcd14f491ae1d77420c5f10a43a4 334 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS04370 0795bcd14f491ae1d77420c5f10a43a4 334 SUPERFAMILY SSF52540 29 252 6.64E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04370 0795bcd14f491ae1d77420c5f10a43a4 334 Pfam PF00005 ABC transporter 46 190 1.6E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04370 0795bcd14f491ae1d77420c5f10a43a4 334 Gene3D G3DSA:3.40.50.300 31 253 9.5E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26240 f9485fa1f6bce9db85c011c8a986f5b8 505 ProSitePatterns PS00571 Amidases signature. 155 186 - T 09-03-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UA74_RS26240 f9485fa1f6bce9db85c011c8a986f5b8 505 Gene3D G3DSA:3.90.1300.10 5 489 5.0E-172 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS26240 f9485fa1f6bce9db85c011c8a986f5b8 505 SUPERFAMILY SSF75304 4 485 5.1E-158 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS26240 f9485fa1f6bce9db85c011c8a986f5b8 505 Pfam PF01425 Amidase 26 476 9.3E-159 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS26240 f9485fa1f6bce9db85c011c8a986f5b8 505 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 486 6.0E-188 T 09-03-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS26240 f9485fa1f6bce9db85c011c8a986f5b8 505 PIRSF PIRSF001221 4 454 1.1E-43 T 09-03-2017 UA74_RS26240 f9485fa1f6bce9db85c011c8a986f5b8 505 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 13 489 91.586 T 09-03-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS18200 cb9fd2188efba1b05ea72eb57a814cbf 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 284 2.0E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18200 cb9fd2188efba1b05ea72eb57a814cbf 294 Gene3D G3DSA:1.10.3720.10 5 284 3.2E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18200 cb9fd2188efba1b05ea72eb57a814cbf 294 SUPERFAMILY SSF161098 55 281 9.94E-58 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 310 2.8E-120 T 09-03-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 Gene3D G3DSA:1.20.120.640 303 401 2.7E-16 T 09-03-2017 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 Gene3D G3DSA:3.40.50.620 21 302 2.5E-96 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 SMART SM00840 345 410 4.8E-9 T 09-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 471 4.3E-135 T 09-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 SUPERFAMILY SSF52374 4 309 2.17E-89 T 09-03-2017 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 2.5E-26 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 2.5E-26 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.5E-26 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.5E-26 T 09-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 473 35.458 T 09-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 Pfam PF09190 DALR domain 345 402 8.3E-7 T 09-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 UA74_RS01660 6bfd558957e656fe92cdee15e482fbd5 476 SUPERFAMILY SSF47323 333 472 4.97E-30 T 09-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_RS09260 2395a1e6bed467bf10d5fb7203ea551c 507 Pfam PF00270 DEAD/DEAH box helicase 91 258 3.4E-41 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS09260 2395a1e6bed467bf10d5fb7203ea551c 507 SUPERFAMILY SSF52540 139 416 1.6E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09260 2395a1e6bed467bf10d5fb7203ea551c 507 SMART SM00487 86 286 5.0E-50 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS09260 2395a1e6bed467bf10d5fb7203ea551c 507 Pfam PF00271 Helicase conserved C-terminal domain 304 401 2.9E-25 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS09260 2395a1e6bed467bf10d5fb7203ea551c 507 Gene3D G3DSA:3.40.50.300 64 275 1.1E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09260 2395a1e6bed467bf10d5fb7203ea551c 507 SMART SM00490 320 401 1.3E-31 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS09260 2395a1e6bed467bf10d5fb7203ea551c 507 Gene3D G3DSA:3.40.50.300 276 430 1.9E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03935 8b24e579f1f50659a4cf1029fb148ede 287 Gene3D G3DSA:1.10.260.40 7 71 4.5E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS03935 8b24e579f1f50659a4cf1029fb148ede 287 SUPERFAMILY SSF47413 18 72 5.32E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS03935 8b24e579f1f50659a4cf1029fb148ede 287 SMART SM00530 20 76 1.3E-4 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS03935 8b24e579f1f50659a4cf1029fb148ede 287 Pfam PF13560 Helix-turn-helix domain 17 74 5.6E-10 T 09-03-2017 UA74_RS28020 70a6aecadb51ff31619693666040dd09 475 SUPERFAMILY SSF53720 7 437 1.83E-91 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS28020 70a6aecadb51ff31619693666040dd09 475 Pfam PF00171 Aldehyde dehydrogenase family 22 439 6.6E-88 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS28020 70a6aecadb51ff31619693666040dd09 475 Gene3D G3DSA:3.40.309.10 273 436 8.8E-40 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS28020 70a6aecadb51ff31619693666040dd09 475 Gene3D G3DSA:3.40.605.10 6 272 1.6E-54 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 SUPERFAMILY SSF56574 7 373 2.88E-86 T 09-03-2017 IPR023796 Serpin domain UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 ProSitePatterns PS00284 Serpins signature. 346 356 - T 09-03-2017 IPR023795 Serpin, conserved site UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 SMART SM00093 13 373 1.4E-67 T 09-03-2017 IPR023796 Serpin domain UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 Gene3D G3DSA:3.30.497.10 266 319 3.9E-54 T 09-03-2017 UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 Gene3D G3DSA:3.30.497.10 8 175 3.9E-54 T 09-03-2017 UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 Gene3D G3DSA:2.30.39.10 176 254 5.5E-31 T 09-03-2017 UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 Gene3D G3DSA:2.30.39.10 320 373 5.5E-31 T 09-03-2017 UA74_RS24470 c19f4d893d6729ca13d8c7d56a57c87b 374 Pfam PF00079 Serpin (serine protease inhibitor) 10 373 2.6E-79 T 09-03-2017 IPR023796 Serpin domain UA74_RS17185 1fc173a43479ae261412f92b83229e40 334 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 22 225 3.3E-30 T 09-03-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 UA74_RS17185 1fc173a43479ae261412f92b83229e40 334 Gene3D G3DSA:3.40.50.720 150 285 3.9E-17 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17185 1fc173a43479ae261412f92b83229e40 334 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 5 327 6.0E-112 T 09-03-2017 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB UA74_RS17185 1fc173a43479ae261412f92b83229e40 334 PIRSF PIRSF001439 5 327 5.1E-63 T 09-03-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 UA74_RS17185 1fc173a43479ae261412f92b83229e40 334 SUPERFAMILY SSF51735 9 326 3.77E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17185 1fc173a43479ae261412f92b83229e40 334 Gene3D G3DSA:3.30.1780.10 7 149 2.6E-38 T 09-03-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 UA74_RS27060 deeb066bd53481119191c0041da34fe0 172 Pfam PF03703 Bacterial PH domain 72 143 2.4E-18 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 Gene3D G3DSA:3.30.9.10 279 385 2.1E-29 T 09-03-2017 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 Pfam PF01266 FAD dependent oxidoreductase 10 422 3.2E-58 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 SUPERFAMILY SSF54373 292 385 9.94E-17 T 09-03-2017 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 Gene3D G3DSA:3.50.50.60 255 278 6.3E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 Gene3D G3DSA:3.50.50.60 152 189 6.3E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 Gene3D G3DSA:3.50.50.60 10 84 6.3E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 Gene3D G3DSA:3.50.50.60 386 442 6.3E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 SUPERFAMILY SSF51971 371 427 1.29E-35 T 09-03-2017 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 SUPERFAMILY SSF51971 263 305 1.29E-35 T 09-03-2017 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 SUPERFAMILY SSF51971 9 185 1.29E-35 T 09-03-2017 UA74_RS01905 788a22c4305984d07a190ab8c290e14c 463 Gene3D G3DSA:3.30.9.10 85 151 6.6E-4 T 09-03-2017 UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 419 506 1.3E-5 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 71 338 2.1E-51 T 09-03-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 Gene3D G3DSA:3.40.50.1820 281 391 1.0E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 Gene3D G3DSA:3.40.50.1820 42 222 1.0E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 Gene3D G3DSA:2.60.120.260 398 508 7.3E-13 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 SMART SM00939 361 530 2.5E-10 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 SUPERFAMILY SSF49785 386 510 6.16E-14 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 423 529 7.7E-20 T 09-03-2017 IPR005674 CocE/Serine esterase GO:0016787 UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 75 417 3.2E-81 T 09-03-2017 IPR005674 CocE/Serine esterase GO:0016787 UA74_RS24355 0bf4441cb958a8ba1a4916c328117e54 575 SUPERFAMILY SSF53474 65 395 5.51E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27445 fee58c4141b04d208ed95aca3877824c 68 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 36 9.9E-6 T 09-03-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 UA74_RS27445 fee58c4141b04d208ed95aca3877824c 68 SUPERFAMILY SSF47598 3 60 3.34E-6 T 09-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 UA74_RS13415 f95350893c3b96e54cb90fab99e6e462 100 Gene3D G3DSA:1.20.1530.10 31 74 8.8E-4 T 09-03-2017 IPR023171 Na/H antiporter domain UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Gene3D G3DSA:2.40.30.10 940 1037 7.4E-33 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 ProSitePatterns PS01176 Initiation factor 2 signature. 990 1012 - T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 PRINTS PR01217 Proline rich extensin signature 163 188 1.5E-10 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 PRINTS PR01217 Proline rich extensin signature 134 151 1.5E-10 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 PRINTS PR01217 Proline rich extensin signature 69 81 1.5E-10 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 PRINTS PR01217 Proline rich extensin signature 85 106 1.5E-10 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 PRINTS PR01217 Proline rich extensin signature 117 133 1.5E-10 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 SUPERFAMILY SSF52156 818 945 1.7E-33 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 SUPERFAMILY SSF50447 940 1037 2.55E-27 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Gene3D G3DSA:3.40.50.300 534 698 3.1E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 SUPERFAMILY SSF52540 533 700 7.02E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Gene3D G3DSA:3.40.50.10050 837 917 1.4E-18 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Gene3D G3DSA:2.40.30.10 709 803 5.1E-20 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 SUPERFAMILY SSF50447 711 794 2.29E-22 T 09-03-2017 IPR009000 Translation protein, beta-barrel domain UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 446 1037 3.9E-221 T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 536 695 1.3E-30 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 1037 16.702 T 09-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 4 51 1.7E-14 T 09-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Pfam PF00009 Elongation factor Tu GTP binding domain 538 698 5.6E-33 T 09-03-2017 UA74_RS09330 f4cfc23f0cf90aac00443e77a1964df5 1038 Pfam PF11987 Translation-initiation factor 2 825 928 7.1E-31 T 09-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 UA74_RS07390 f2f47cf18d8077e0a28e61a5ee226005 166 ProSitePatterns PS00893 Nudix box signature. 46 67 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS07390 f2f47cf18d8077e0a28e61a5ee226005 166 SUPERFAMILY SSF55811 14 143 2.57E-24 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS07390 f2f47cf18d8077e0a28e61a5ee226005 166 PRINTS PR00502 NUDIX hydrolase family signature 55 70 5.3E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS07390 f2f47cf18d8077e0a28e61a5ee226005 166 PRINTS PR00502 NUDIX hydrolase family signature 41 55 5.3E-5 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS07390 f2f47cf18d8077e0a28e61a5ee226005 166 Gene3D G3DSA:3.90.79.10 13 146 1.5E-27 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS07390 f2f47cf18d8077e0a28e61a5ee226005 166 Pfam PF00293 NUDIX domain 14 129 1.5E-17 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS12450 19d9fd7c08ed07ba32612166bf504621 262 Gene3D G3DSA:3.20.20.70 4 255 5.1E-104 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS12450 19d9fd7c08ed07ba32612166bf504621 262 SUPERFAMILY SSF51351 3 255 4.71E-90 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12450 19d9fd7c08ed07ba32612166bf504621 262 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 09-03-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12450 19d9fd7c08ed07ba32612166bf504621 262 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 7 247 3.7E-57 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12450 19d9fd7c08ed07ba32612166bf504621 262 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 256 39.393 T 09-03-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12450 19d9fd7c08ed07ba32612166bf504621 262 Pfam PF00121 Triosephosphate isomerase 7 253 8.5E-88 T 09-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS09120 8c81d129bd7da946d77155f611fbb1e4 278 SUPERFAMILY SSF55729 73 273 1.58E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09120 8c81d129bd7da946d77155f611fbb1e4 278 PIRSF PIRSF021603 2 278 4.1E-113 T 09-03-2017 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like UA74_RS09120 8c81d129bd7da946d77155f611fbb1e4 278 Gene3D G3DSA:3.40.630.30 119 273 5.6E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09120 8c81d129bd7da946d77155f611fbb1e4 278 Pfam PF13312 Domain of unknown function (DUF4081) 48 150 4.1E-42 T 09-03-2017 IPR025289 Domain of unknown function DUF4081 UA74_RS09120 8c81d129bd7da946d77155f611fbb1e4 278 Pfam PF08445 FR47-like protein 206 269 7.0E-13 T 09-03-2017 IPR013653 FR47-like GO:0016747 UA74_RS06010 e794c22d9af5e66cf7830e693adaea61 595 SUPERFAMILY SSF50934 112 213 1.31E-14 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS06010 e794c22d9af5e66cf7830e693adaea61 595 SUPERFAMILY SSF50934 27 59 1.31E-14 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS06010 e794c22d9af5e66cf7830e693adaea61 595 SUPERFAMILY SSF89372 293 478 2.09E-14 T 09-03-2017 UA74_RS06010 e794c22d9af5e66cf7830e693adaea61 595 Pfam PF14517 Tachylectin 7 228 1.6E-23 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS06010 e794c22d9af5e66cf7830e693adaea61 595 Gene3D G3DSA:2.115.10.10 74 248 6.2E-23 T 09-03-2017 IPR023294 Tachylectin 2 UA74_RS30370 ecc6314f9d06bb0e22ec5ed27b33bf21 182 SUPERFAMILY SSF55811 31 159 6.5E-31 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS30370 ecc6314f9d06bb0e22ec5ed27b33bf21 182 PRINTS PR00502 NUDIX hydrolase family signature 58 72 1.2E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS30370 ecc6314f9d06bb0e22ec5ed27b33bf21 182 PRINTS PR00502 NUDIX hydrolase family signature 72 87 1.2E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS30370 ecc6314f9d06bb0e22ec5ed27b33bf21 182 ProSitePatterns PS00893 Nudix box signature. 63 84 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS30370 ecc6314f9d06bb0e22ec5ed27b33bf21 182 Gene3D G3DSA:3.90.79.10 32 161 7.4E-30 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS30370 ecc6314f9d06bb0e22ec5ed27b33bf21 182 Pfam PF00293 NUDIX domain 46 157 6.5E-21 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS22300 74170f13d666813305a2bf246b0d8442 335 SUPERFAMILY SSF51679 2 329 1.11E-70 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS22300 74170f13d666813305a2bf246b0d8442 335 Gene3D G3DSA:3.20.20.30 3 327 2.6E-76 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS22300 74170f13d666813305a2bf246b0d8442 335 Pfam PF00296 Luciferase-like monooxygenase 3 289 3.1E-49 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS05980 6227d5cb488a4b621b664d686c011a5c 640 Pfam PF01435 Peptidase family M48 77 304 5.5E-15 T 09-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UA74_RS05980 6227d5cb488a4b621b664d686c011a5c 640 Gene3D G3DSA:3.30.2010.10 74 162 1.0E-13 T 09-03-2017 UA74_RS15505 3cc47d2648a06930521b5fb36a3a6b95 321 Pfam PF07224 Chlorophyllase 37 153 4.1E-5 T 09-03-2017 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 UA74_RS15505 3cc47d2648a06930521b5fb36a3a6b95 321 Gene3D G3DSA:3.40.50.1820 19 258 3.9E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS15505 3cc47d2648a06930521b5fb36a3a6b95 321 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 22 57 - T 09-03-2017 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 UA74_RS15505 3cc47d2648a06930521b5fb36a3a6b95 321 SUPERFAMILY SSF53474 13 230 6.6E-26 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS04355 4060d3e8829001e1e9c6b655a9c099f6 173 Gene3D G3DSA:1.10.10.10 7 153 3.6E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04355 4060d3e8829001e1e9c6b655a9c099f6 173 SMART SM00347 34 138 3.4E-4 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS04355 4060d3e8829001e1e9c6b655a9c099f6 173 SUPERFAMILY SSF46785 16 153 7.93E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04355 4060d3e8829001e1e9c6b655a9c099f6 173 Pfam PF12802 MarR family 39 101 9.6E-9 T 09-03-2017 UA74_RS06865 094d32634d5c22617fbf7f3d4d5ef347 243 Pfam PF00182 Chitinase class I 41 243 2.2E-43 T 09-03-2017 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 UA74_RS06865 094d32634d5c22617fbf7f3d4d5ef347 243 Gene3D G3DSA:1.10.530.10 41 99 1.7E-53 T 09-03-2017 UA74_RS06865 094d32634d5c22617fbf7f3d4d5ef347 243 Gene3D G3DSA:1.10.530.10 163 243 1.7E-53 T 09-03-2017 UA74_RS06865 094d32634d5c22617fbf7f3d4d5ef347 243 PIRSF PIRSF001060 8 243 6.5E-80 T 09-03-2017 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 UA74_RS06865 094d32634d5c22617fbf7f3d4d5ef347 243 Gene3D G3DSA:3.30.20.10 107 162 6.3E-24 T 09-03-2017 UA74_RS06865 094d32634d5c22617fbf7f3d4d5ef347 243 SUPERFAMILY SSF53955 39 243 3.37E-65 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS01015 c8c406b92742a5178b3c76cac397e375 178 Gene3D G3DSA:3.40.50.300 1 154 7.4E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01015 c8c406b92742a5178b3c76cac397e375 178 SUPERFAMILY SSF52540 1 159 9.94E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 SUPERFAMILY SSF55979 245 367 2.77E-9 T 09-03-2017 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 9 340 8.8E-41 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 339 5.3E-6 T 09-03-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 SUPERFAMILY SSF55979 4 120 6.8E-15 T 09-03-2017 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 SMART SM00480 19 364 1.5E-20 T 09-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 Gene3D G3DSA:3.10.150.10 130 246 4.3E-23 T 09-03-2017 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 Gene3D G3DSA:3.10.150.10 5 118 1.5E-18 T 09-03-2017 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 133 241 4.7E-16 T 09-03-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 SUPERFAMILY SSF55979 131 245 1.26E-17 T 09-03-2017 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 Gene3D G3DSA:3.10.150.10 252 367 1.0E-8 T 09-03-2017 UA74_RS01215 c0a2bf66a0a56efe40b266489e1fab07 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 5 119 2.5E-16 T 09-03-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS26170 f45c7dbce9db2e796d2aa661ed846a58 722 Pfam PF00069 Protein kinase domain 16 262 2.4E-32 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS26170 f45c7dbce9db2e796d2aa661ed846a58 722 Gene3D G3DSA:1.10.510.10 94 262 4.4E-37 T 09-03-2017 UA74_RS26170 f45c7dbce9db2e796d2aa661ed846a58 722 Gene3D G3DSA:3.30.200.20 8 88 7.5E-13 T 09-03-2017 UA74_RS26170 f45c7dbce9db2e796d2aa661ed846a58 722 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS26170 f45c7dbce9db2e796d2aa661ed846a58 722 SUPERFAMILY SSF56112 11 267 1.17E-58 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS26170 f45c7dbce9db2e796d2aa661ed846a58 722 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 133 145 - T 09-03-2017 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS16830 014a150c1c67fb4b57e8248ab321ee8a 290 Pfam PF13649 Methyltransferase domain 58 154 3.7E-17 T 09-03-2017 UA74_RS16830 014a150c1c67fb4b57e8248ab321ee8a 290 Gene3D G3DSA:3.40.50.150 41 250 7.3E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS16830 014a150c1c67fb4b57e8248ab321ee8a 290 SUPERFAMILY SSF53335 39 225 1.2E-32 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20525 2021d956d480e852562d3d3e979e94f7 247 Gene3D G3DSA:2.40.30.10 1 115 4.6E-28 T 09-03-2017 UA74_RS20525 2021d956d480e852562d3d3e979e94f7 247 SUPERFAMILY SSF63380 2 115 7.23E-5 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS20525 2021d956d480e852562d3d3e979e94f7 247 Gene3D G3DSA:3.40.50.80 123 247 6.8E-38 T 09-03-2017 UA74_RS20525 2021d956d480e852562d3d3e979e94f7 247 Pfam PF08021 Siderophore-interacting FAD-binding domain 3 114 1.2E-26 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting UA74_RS20525 2021d956d480e852562d3d3e979e94f7 247 Pfam PF04954 Siderophore-interacting protein 132 243 3.0E-32 T 09-03-2017 IPR007037 Siderophore-interacting protein UA74_RS17820 4da0234774cc75badabce1b0b100fc53 196 SUPERFAMILY SSF55729 11 175 6.23E-25 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS17820 4da0234774cc75badabce1b0b100fc53 196 Pfam PF13302 Acetyltransferase (GNAT) domain 20 154 2.1E-13 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS17820 4da0234774cc75badabce1b0b100fc53 196 Gene3D G3DSA:3.40.630.30 8 185 3.2E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09460 1e367679c727afa8df4f55d9c55cdcc1 461 Pfam PF07690 Major Facilitator Superfamily 57 372 5.9E-20 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS09460 1e367679c727afa8df4f55d9c55cdcc1 461 SUPERFAMILY SSF103473 22 444 1.1E-40 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS09460 1e367679c727afa8df4f55d9c55cdcc1 461 Gene3D G3DSA:1.20.1250.20 238 443 9.2E-15 T 09-03-2017 UA74_RS09460 1e367679c727afa8df4f55d9c55cdcc1 461 Gene3D G3DSA:1.20.1250.20 41 224 7.4E-13 T 09-03-2017 UA74_RS24560 fcdc93cce98306a67963b51d81424a4d 292 Pfam PF00005 ABC transporter 21 154 1.1E-14 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS24560 fcdc93cce98306a67963b51d81424a4d 292 SMART SM00382 29 206 2.4E-4 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS24560 fcdc93cce98306a67963b51d81424a4d 292 Gene3D G3DSA:3.40.50.300 5 219 3.4E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24560 fcdc93cce98306a67963b51d81424a4d 292 SUPERFAMILY SSF52540 4 219 2.67E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27480 ba1799c23329bac48119f42e6fa63b88 215 Gene3D G3DSA:3.40.50.300 10 207 1.1E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27480 ba1799c23329bac48119f42e6fa63b88 215 SUPERFAMILY SSF52540 11 204 3.22E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27480 ba1799c23329bac48119f42e6fa63b88 215 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 11 193 2.2E-33 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_RS27480 ba1799c23329bac48119f42e6fa63b88 215 Hamap MF_00165 Thymidylate kinase [tmk]. 13 207 17.031 T 09-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_RS27480 ba1799c23329bac48119f42e6fa63b88 215 Pfam PF02223 Thymidylate kinase 17 171 7.4E-32 T 09-03-2017 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 ProSitePatterns PS00480 Citrate synthase signature. 294 306 - T 09-03-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 SUPERFAMILY SSF48256 77 400 7.85E-66 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 SUPERFAMILY SSF46955 12 64 1.46E-6 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 Gene3D G3DSA:1.10.230.10 295 355 2.3E-11 T 09-03-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 Pfam PF00285 Citrate synthase, C-terminal domain 76 391 3.2E-60 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 Gene3D G3DSA:1.10.580.10 81 294 4.9E-43 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 Pfam PF12728 Helix-turn-helix domain 13 65 1.0E-8 T 09-03-2017 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 236 264 6.6E-26 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 287 307 6.6E-26 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 342 358 6.6E-26 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 214 229 6.6E-26 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 362 376 6.6E-26 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS14260 0ddaad12cc5a519c52720337a9ea5639 403 Gene3D G3DSA:1.10.1660.10 14 80 7.6E-4 T 09-03-2017 UA74_RS22855 33bcdb4f7c2b5110539d29732d3b9633 340 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 17 25 - T 09-03-2017 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 UA74_RS22855 33bcdb4f7c2b5110539d29732d3b9633 340 SUPERFAMILY SSF51556 3 319 3.81E-81 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS22855 33bcdb4f7c2b5110539d29732d3b9633 340 Pfam PF02126 Phosphotriesterase family 13 318 1.7E-91 T 09-03-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 UA74_RS22855 33bcdb4f7c2b5110539d29732d3b9633 340 Gene3D G3DSA:3.20.20.140 3 319 1.0E-102 T 09-03-2017 UA74_RS26885 6eb93e71a24a686ac1294a18b711ea72 364 SUPERFAMILY SSF53756 22 363 1.32E-59 T 09-03-2017 UA74_RS26885 6eb93e71a24a686ac1294a18b711ea72 364 Pfam PF13692 Glycosyl transferases group 1 205 327 5.8E-20 T 09-03-2017 UA74_RS26885 6eb93e71a24a686ac1294a18b711ea72 364 Gene3D G3DSA:3.40.50.2000 165 333 1.4E-21 T 09-03-2017 UA74_RS26885 6eb93e71a24a686ac1294a18b711ea72 364 Pfam PF13439 Glycosyltransferase Family 4 25 184 1.2E-11 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS28075 02541d414e14d89b35bc828b62031eca 190 Pfam PF08281 Sigma-70, region 4 131 180 1.1E-11 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28075 02541d414e14d89b35bc828b62031eca 190 SUPERFAMILY SSF88946 12 112 2.51E-17 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28075 02541d414e14d89b35bc828b62031eca 190 SUPERFAMILY SSF88659 112 185 2.62E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28075 02541d414e14d89b35bc828b62031eca 190 Gene3D G3DSA:1.10.1740.10 11 124 1.7E-19 T 09-03-2017 UA74_RS28075 02541d414e14d89b35bc828b62031eca 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 1.5E-26 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28075 02541d414e14d89b35bc828b62031eca 190 Gene3D G3DSA:1.10.10.10 125 185 2.2E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28075 02541d414e14d89b35bc828b62031eca 190 Pfam PF04542 Sigma-70 region 2 26 98 3.4E-13 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS24990 17b74616ef189e7e50fa8fe605b5c2dc 261 Gene3D G3DSA:3.60.21.10 1 34 3.0E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS24990 17b74616ef189e7e50fa8fe605b5c2dc 261 Gene3D G3DSA:3.60.21.10 86 248 3.0E-17 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS24990 17b74616ef189e7e50fa8fe605b5c2dc 261 Pfam PF00149 Calcineurin-like phosphoesterase 2 232 2.1E-7 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS24990 17b74616ef189e7e50fa8fe605b5c2dc 261 SUPERFAMILY SSF56300 87 254 6.84E-29 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS24990 17b74616ef189e7e50fa8fe605b5c2dc 261 SUPERFAMILY SSF56300 2 43 6.84E-29 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS23915 854b6880c06c84a6b7fadf5b708fb0b8 415 SUPERFAMILY SSF53850 12 413 1.14E-56 T 09-03-2017 UA74_RS23915 854b6880c06c84a6b7fadf5b708fb0b8 415 Pfam PF01547 Bacterial extracellular solute-binding protein 36 321 2.7E-30 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS23915 854b6880c06c84a6b7fadf5b708fb0b8 415 Gene3D G3DSA:3.40.190.10 21 142 7.1E-30 T 09-03-2017 UA74_RS23915 854b6880c06c84a6b7fadf5b708fb0b8 415 Gene3D G3DSA:3.40.190.10 309 342 7.1E-30 T 09-03-2017 UA74_RS23915 854b6880c06c84a6b7fadf5b708fb0b8 415 Gene3D G3DSA:3.40.190.10 143 308 2.6E-14 T 09-03-2017 UA74_RS13160 b31ee25ab4a05d6e286a6c15d2bf95eb 250 Pfam PF05331 Protein of unknown function (DUF742) 140 250 1.8E-28 T 09-03-2017 IPR007995 Protein of unknown function DUF742 UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 182 1.0E-48 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 Pfam PF04229 GrpB protein 213 325 8.6E-14 T 09-03-2017 IPR007344 GrpB/Dephospho-CoA kinase UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 Pfam PF01121 Dephospho-CoA kinase 4 180 1.7E-59 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 SUPERFAMILY SSF81301 214 325 2.88E-17 T 09-03-2017 UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 192 26.261 T 09-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 SUPERFAMILY SSF52540 3 194 3.93E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 Gene3D G3DSA:3.40.50.300 2 192 1.3E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10750 967a528fd517ca5a8be5c0fd879fcbca 326 Gene3D G3DSA:3.30.460.10 213 325 3.0E-20 T 09-03-2017 UA74_RS21275 7d1dfb9e6ab01a97cca7a5edda94ceea 439 Gene3D G3DSA:3.40.50.150 147 435 1.5E-90 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21275 7d1dfb9e6ab01a97cca7a5edda94ceea 439 Pfam PF02353 Mycolic acid cyclopropane synthetase 152 433 7.2E-84 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21275 7d1dfb9e6ab01a97cca7a5edda94ceea 439 SUPERFAMILY SSF53335 159 438 7.59E-66 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21275 7d1dfb9e6ab01a97cca7a5edda94ceea 439 PIRSF PIRSF003085 40 439 1.1E-114 T 09-03-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 UA74_RS02615 40f4ab033b807709e3e23c7029d58d29 349 SUPERFAMILY SSF103481 78 180 1.31E-11 T 09-03-2017 UA74_RS02615 40f4ab033b807709e3e23c7029d58d29 349 TIGRFAM TIGR00688 rarD: protein RarD 45 293 1.2E-55 T 09-03-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 UA74_RS02615 40f4ab033b807709e3e23c7029d58d29 349 SUPERFAMILY SSF103481 242 319 1.09E-7 T 09-03-2017 UA74_RS02615 40f4ab033b807709e3e23c7029d58d29 349 Pfam PF00892 EamA-like transporter family 44 178 2.4E-9 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS00405 3524cb49760e345f6be1dd04c4e8e1bc 116 Pfam PF04341 Protein of unknown function, DUF485 22 109 2.2E-35 T 09-03-2017 IPR007436 Protein of unknown function DUF485 UA74_RS12305 a7249566d7a00608441a818a1a87df5d 280 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 92 105 - T 09-03-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12305 a7249566d7a00608441a818a1a87df5d 280 SMART SM00934 18 267 5.9E-32 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS12305 a7249566d7a00608441a818a1a87df5d 280 Gene3D G3DSA:3.20.20.70 7 271 2.6E-57 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS12305 a7249566d7a00608441a818a1a87df5d 280 SUPERFAMILY SSF51366 5 268 2.4E-57 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 UA74_RS12305 a7249566d7a00608441a818a1a87df5d 280 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 3 277 32.495 T 09-03-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 UA74_RS12305 a7249566d7a00608441a818a1a87df5d 280 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 267 1.6E-78 T 09-03-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 UA74_RS12305 a7249566d7a00608441a818a1a87df5d 280 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 18 266 3.4E-36 T 09-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_RS13080 b4ef09699c87d31a80646509d7f98c93 229 Pfam PF00005 ABC transporter 32 178 2.6E-28 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13080 b4ef09699c87d31a80646509d7f98c93 229 Gene3D G3DSA:3.40.50.300 10 228 9.7E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13080 b4ef09699c87d31a80646509d7f98c93 229 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13080 b4ef09699c87d31a80646509d7f98c93 229 SUPERFAMILY SSF52540 10 227 6.23E-51 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13080 b4ef09699c87d31a80646509d7f98c93 229 SMART SM00382 41 225 1.4E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08570 19bcc618099e413d9ea180ede3cccaf1 233 PIRSF PIRSF010219 1 205 2.1E-70 T 09-03-2017 IPR016566 Uncharacterised conserved protein UCP010219 UA74_RS08570 19bcc618099e413d9ea180ede3cccaf1 233 Pfam PF11361 Protein of unknown function (DUF3159) 5 187 3.6E-65 T 09-03-2017 IPR016566 Uncharacterised conserved protein UCP010219 UA74_RS08790 f032dbc22b677437adf17cd506d772e9 344 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 323 3.6E-87 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS08790 f032dbc22b677437adf17cd506d772e9 344 SUPERFAMILY SSF53659 4 330 4.96E-90 T 09-03-2017 UA74_RS08790 f032dbc22b677437adf17cd506d772e9 344 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 328 30.395 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS08790 f032dbc22b677437adf17cd506d772e9 344 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 328 2.0E-91 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS08790 f032dbc22b677437adf17cd506d772e9 344 Gene3D G3DSA:3.40.718.10 4 328 3.7E-105 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS28475 eeed39de1478dc85aaca94ec2c24ff90 276 SUPERFAMILY SSF55315 6 68 5.65E-6 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS28475 eeed39de1478dc85aaca94ec2c24ff90 276 Gene3D G3DSA:3.30.1330.30 7 66 3.5E-5 T 09-03-2017 IPR029064 50S ribosomal protein L30e-like UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 Gene3D G3DSA:1.10.10.10 4 85 2.1E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 Gene3D G3DSA:3.40.190.10 164 259 1.8E-9 T 09-03-2017 UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.0E-9 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.0E-9 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.0E-9 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.8E-21 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 Pfam PF03466 LysR substrate binding domain 116 287 3.5E-16 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 SUPERFAMILY SSF53850 114 288 1.72E-16 T 09-03-2017 UA74_RS22845 84be2bc69a0b5f5c1ceabcf12777e309 323 SUPERFAMILY SSF46785 4 99 4.09E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03730 3fe549d0fb68a58d391b43cd17fe9568 322 Gene3D G3DSA:1.10.530.10 168 197 4.5E-10 T 09-03-2017 UA74_RS03730 3fe549d0fb68a58d391b43cd17fe9568 322 Gene3D G3DSA:1.10.530.10 237 313 4.5E-10 T 09-03-2017 UA74_RS03730 3fe549d0fb68a58d391b43cd17fe9568 322 SUPERFAMILY SSF53955 151 317 4.16E-34 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS03730 3fe549d0fb68a58d391b43cd17fe9568 322 Pfam PF13406 Transglycosylase SLT domain 236 279 5.2E-8 T 09-03-2017 IPR031304 Transglycosylase SLT domain 2 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 SUPERFAMILY SSF55874 206 360 7.2E-29 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 203 3.5E-8 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 SMART SM00304 86 139 2.1E-9 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 SMART SM00388 140 204 3.1E-7 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 SMART SM00387 246 360 1.5E-18 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 SUPERFAMILY SSF47384 123 203 1.96E-13 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 338 4.8E-9 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 4.8E-9 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 357 4.8E-9 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 Pfam PF00672 HAMP domain 68 136 3.9E-13 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 Gene3D G3DSA:3.30.565.10 209 362 1.8E-30 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 SUPERFAMILY SSF158472 88 136 1.31E-6 T 09-03-2017 UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 359 1.4E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS19300 f11c074f7807201e217400bff7e7f8bd 369 Gene3D G3DSA:1.10.287.130 130 200 2.4E-9 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS19345 dd603946f76c0befb2c1e33647d5deae 138 Pfam PF07876 Stress responsive A/B Barrel Domain 2 92 8.3E-14 T 09-03-2017 IPR013097 Stress responsive alpha-beta barrel UA74_RS19345 dd603946f76c0befb2c1e33647d5deae 138 SUPERFAMILY SSF54909 1 97 2.31E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS19345 dd603946f76c0befb2c1e33647d5deae 138 SMART SM00886 2 93 5.7E-13 T 09-03-2017 IPR013097 Stress responsive alpha-beta barrel UA74_RS19345 dd603946f76c0befb2c1e33647d5deae 138 Gene3D G3DSA:3.30.70.900 1 91 1.8E-14 T 09-03-2017 UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 Gene3D G3DSA:3.40.50.300 277 502 1.7E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 Pfam PF00005 ABC transporter 302 442 2.9E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 Pfam PF00005 ABC transporter 18 169 5.5E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 SUPERFAMILY SSF52540 278 502 4.1E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 SUPERFAMILY SSF52540 2 232 3.39E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 SMART SM00382 310 491 5.4E-9 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 SMART SM00382 27 218 3.9E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 Gene3D G3DSA:3.40.50.300 1 231 6.1E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13170 5c6381e72ace6225c59b5f16f625d4ec 538 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS14665 68868d894525c9b4adb830a2a738628f 242 Gene3D G3DSA:3.40.50.150 33 219 2.3E-15 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14665 68868d894525c9b4adb830a2a738628f 242 SUPERFAMILY SSF53335 37 218 1.28E-15 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14665 68868d894525c9b4adb830a2a738628f 242 Pfam PF05175 Methyltransferase small domain 60 155 1.5E-5 T 09-03-2017 IPR007848 Methyltransferase small domain GO:0008168 UA74_RS10660 ba8c1dac1256667602008d54e972566b 534 Pfam PF13699 Domain of unknown function (DUF4157) 34 103 2.1E-24 T 09-03-2017 IPR025295 Domain of unknown function DUF4157 UA74_RS04620 dc311524cf9f1abcf8a95a956c1a5db4 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 185 2.7E-29 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04620 dc311524cf9f1abcf8a95a956c1a5db4 197 SUPERFAMILY SSF88659 127 186 2.24E-17 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04620 dc311524cf9f1abcf8a95a956c1a5db4 197 Gene3D G3DSA:1.10.10.10 129 187 5.5E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04620 dc311524cf9f1abcf8a95a956c1a5db4 197 Pfam PF08281 Sigma-70, region 4 131 181 7.2E-17 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04620 dc311524cf9f1abcf8a95a956c1a5db4 197 SUPERFAMILY SSF88946 29 107 1.32E-23 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04620 dc311524cf9f1abcf8a95a956c1a5db4 197 Pfam PF04542 Sigma-70 region 2 33 98 5.8E-20 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04620 dc311524cf9f1abcf8a95a956c1a5db4 197 Gene3D G3DSA:1.10.1740.10 28 119 1.1E-25 T 09-03-2017 UA74_RS01820 bf06d49070e9e9ed16d3e40361c178bf 300 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 47 262 8.1E-33 T 09-03-2017 IPR008775 Phytanoyl-CoA dioxygenase UA74_RS01820 bf06d49070e9e9ed16d3e40361c178bf 300 Gene3D G3DSA:2.60.120.620 35 277 3.8E-51 T 09-03-2017 UA74_RS01820 bf06d49070e9e9ed16d3e40361c178bf 300 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 25 299 4.9E-129 T 09-03-2017 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 UA74_RS01820 bf06d49070e9e9ed16d3e40361c178bf 300 SUPERFAMILY SSF51197 36 298 1.28E-56 T 09-03-2017 UA74_RS20785 d2af809dcc337638b48df0022e77230d 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 317 7.2E-44 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS29270 cca7b548ee063fb4fe8a5d8af2a574d1 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 299 1.4E-27 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS29270 cca7b548ee063fb4fe8a5d8af2a574d1 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 31 297 3.3E-78 T 09-03-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 UA74_RS29270 cca7b548ee063fb4fe8a5d8af2a574d1 304 Gene3D G3DSA:1.10.3720.10 30 297 7.0E-42 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS29270 cca7b548ee063fb4fe8a5d8af2a574d1 304 SUPERFAMILY SSF161098 35 291 6.17E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01535 1bed4be1fc9ca05f9bca97998dd1483a 166 Gene3D G3DSA:3.30.70.560 3 151 6.7E-45 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS01535 1bed4be1fc9ca05f9bca97998dd1483a 166 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 130 2.5E-29 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS01535 1bed4be1fc9ca05f9bca97998dd1483a 166 SUPERFAMILY SSF55083 1 151 9.81E-43 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS01535 1bed4be1fc9ca05f9bca97998dd1483a 166 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 85 96 - T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS01535 1bed4be1fc9ca05f9bca97998dd1483a 166 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 130 7.4E-34 T 09-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_RS15665 0b6ec19a96573d008db75f33f870c077 143 Gene3D G3DSA:3.10.180.10 11 139 2.5E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15665 0b6ec19a96573d008db75f33f870c077 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 131 1.7E-6 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS15665 0b6ec19a96573d008db75f33f870c077 143 SUPERFAMILY SSF54593 10 133 5.5E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS21080 c6d98c17a033a01931b338586e87d4f2 437 Pfam PF00534 Glycosyl transferases group 1 224 404 3.9E-25 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS21080 c6d98c17a033a01931b338586e87d4f2 437 SUPERFAMILY SSF53756 18 420 3.95E-47 T 09-03-2017 UA74_RS21080 c6d98c17a033a01931b338586e87d4f2 437 Gene3D G3DSA:3.40.50.2000 219 404 8.5E-24 T 09-03-2017 UA74_RS06575 8bf13dd8dbdb922281acced30f68d83d 298 SUPERFAMILY SSF53901 31 195 7.2E-8 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS17910 01efd35bb2a52663f2256078e7eb6f65 412 Gene3D G3DSA:3.40.190.10 17 145 1.1E-11 T 09-03-2017 UA74_RS17910 01efd35bb2a52663f2256078e7eb6f65 412 Pfam PF13416 Bacterial extracellular solute-binding protein 38 336 5.3E-21 T 09-03-2017 UA74_RS17910 01efd35bb2a52663f2256078e7eb6f65 412 Gene3D G3DSA:3.40.190.10 146 335 1.1E-33 T 09-03-2017 UA74_RS17910 01efd35bb2a52663f2256078e7eb6f65 412 SUPERFAMILY SSF53850 21 401 9.88E-54 T 09-03-2017 UA74_RS04205 2eac7d8e3c4151026acb337d4169bd77 327 Pfam PF02646 RmuC family 61 264 5.8E-38 T 09-03-2017 IPR003798 DNA recombination RmuC UA74_RS19840 e6ecf9cf48dc9192d0282afaa881c619 285 SMART SM00530 20 75 3.4E-4 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS19840 e6ecf9cf48dc9192d0282afaa881c619 285 Gene3D G3DSA:1.10.260.40 12 74 2.7E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS19840 e6ecf9cf48dc9192d0282afaa881c619 285 Pfam PF13560 Helix-turn-helix domain 17 78 2.1E-11 T 09-03-2017 UA74_RS19840 e6ecf9cf48dc9192d0282afaa881c619 285 SUPERFAMILY SSF47413 16 74 6.22E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 Pfam PF00574 Clp protease 12 186 8.3E-78 T 09-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 SUPERFAMILY SSF52096 13 188 5.69E-66 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 106 119 - T 09-03-2017 IPR033135 ClpP, histidine active site UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 PRINTS PR00127 Clp protease catalytic subunit P signature 105 124 1.1E-46 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 PRINTS PR00127 Clp protease catalytic subunit P signature 162 181 1.1E-46 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 PRINTS PR00127 Clp protease catalytic subunit P signature 53 73 1.1E-46 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 PRINTS PR00127 Clp protease catalytic subunit P signature 13 28 1.1E-46 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 PRINTS PR00127 Clp protease catalytic subunit P signature 84 101 1.1E-46 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 187 38.982 T 09-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_RS08170 75be7fb3908d9aa360e2d098e500e129 199 Gene3D G3DSA:3.90.226.10 13 189 5.2E-76 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS17700 0490463e058dcda66362dccd8a65f629 205 SUPERFAMILY SSF52499 4 190 2.35E-39 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS17700 0490463e058dcda66362dccd8a65f629 205 Gene3D G3DSA:3.40.50.850 5 171 2.4E-39 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS17700 0490463e058dcda66362dccd8a65f629 205 Pfam PF00857 Isochorismatase family 7 190 2.2E-36 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS04340 303e577eccf346c318c32b450ed0fb10 168 Gene3D G3DSA:3.90.79.10 24 155 5.0E-10 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS04340 303e577eccf346c318c32b450ed0fb10 168 Pfam PF00293 NUDIX domain 25 108 3.4E-6 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS04340 303e577eccf346c318c32b450ed0fb10 168 SUPERFAMILY SSF55811 21 155 1.11E-11 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS24040 52c6d453183ece8aedf81c951d3dc243 687 SUPERFAMILY SSF82171 28 410 4.19E-35 T 09-03-2017 UA74_RS24040 52c6d453183ece8aedf81c951d3dc243 687 Gene3D G3DSA:3.40.50.1820 424 676 3.5E-63 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24040 52c6d453183ece8aedf81c951d3dc243 687 Gene3D G3DSA:2.130.10.10 305 385 2.2E-11 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS24040 52c6d453183ece8aedf81c951d3dc243 687 Pfam PF00326 Prolyl oligopeptidase family 469 675 1.1E-44 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS24040 52c6d453183ece8aedf81c951d3dc243 687 SUPERFAMILY SSF53474 424 675 1.05E-60 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24040 52c6d453183ece8aedf81c951d3dc243 687 Gene3D G3DSA:2.130.10.10 16 293 2.6E-24 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 466 631 7.0E-39 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 138 347 2.5E-27 T 09-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:3.40.50.1000 473 592 4.6E-36 T 09-03-2017 IPR023214 HAD-like domain UA74_RS25745 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF56784 313 337 3.92E-38 T 09-03-2017 IPR023214 HAD-like domain UA74_RS25745 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF56784 373 433 3.92E-38 T 09-03-2017 IPR023214 HAD-like domain UA74_RS25745 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF56784 468 588 3.92E-38 T 09-03-2017 IPR023214 HAD-like domain UA74_RS25745 726786be75d31a51538187a238e45ffb 712 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 24 705 1.4E-288 T 09-03-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF81665 228 319 1.96E-12 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF81665 45 112 1.96E-12 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 Pfam PF00122 E1-E2 ATPase 81 316 3.9E-39 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:2.70.150.10 61 228 2.1E-19 T 09-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 24 709 39.114 T 09-03-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 Pfam PF00702 haloacid dehalogenase-like hydrolase 323 559 1.6E-32 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 327 333 - T 09-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF81653 138 227 1.57E-19 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:3.40.1110.10 336 472 7.8E-41 T 09-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 325 339 5.0E-26 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 470 481 5.0E-26 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 174 188 5.0E-26 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 568 580 5.0E-26 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 564 5.0E-26 T 09-03-2017 UA74_RS25745 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 492 502 5.0E-26 T 09-03-2017 UA74_RS07375 9ba51bb7eddc7b032fa88bc03fd6b8bd 656 Gene3D G3DSA:3.20.20.80 198 557 1.2E-66 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07375 9ba51bb7eddc7b032fa88bc03fd6b8bd 656 SUPERFAMILY SSF51445 200 559 5.37E-79 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07375 9ba51bb7eddc7b032fa88bc03fd6b8bd 656 SMART SM00642 199 534 6.0E-5 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07375 9ba51bb7eddc7b032fa88bc03fd6b8bd 656 Pfam PF11896 Domain of unknown function (DUF3416) 3 193 2.7E-53 T 09-03-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 UA74_RS07375 9ba51bb7eddc7b032fa88bc03fd6b8bd 656 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 655 44.933 T 09-03-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 UA74_RS28200 3c5eb1fb930aa6f4e27ffeff56582cae 900 SUPERFAMILY SSF140453 159 236 5.23E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS28200 3c5eb1fb930aa6f4e27ffeff56582cae 900 Gene3D G3DSA:1.10.287.1060 159 233 2.2E-4 T 09-03-2017 UA74_RS10225 63f5e1276830dde7329440cd7756601e 363 Gene3D G3DSA:1.10.600.10 19 362 6.3E-84 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS10225 63f5e1276830dde7329440cd7756601e 363 SUPERFAMILY SSF48576 33 362 4.93E-73 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS10225 63f5e1276830dde7329440cd7756601e 363 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS10225 63f5e1276830dde7329440cd7756601e 363 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS10225 63f5e1276830dde7329440cd7756601e 363 Pfam PF00348 Polyprenyl synthetase 41 286 2.9E-52 T 09-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 UA74_RS24625 79fac5caa04c2821b15b5badfdb66082 408 SMART SM00729 29 254 5.9E-57 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS24625 79fac5caa04c2821b15b5badfdb66082 408 SUPERFAMILY SSF102114 22 407 1.7E-102 T 09-03-2017 UA74_RS24625 79fac5caa04c2821b15b5badfdb66082 408 Pfam PF04055 Radical SAM superfamily 34 209 1.9E-19 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS24625 79fac5caa04c2821b15b5badfdb66082 408 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 366 4.5E-68 T 09-03-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 UA74_RS24625 79fac5caa04c2821b15b5badfdb66082 408 Gene3D G3DSA:3.80.30.20 32 268 4.0E-33 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe UA74_RS19795 02c7953ed5715301bef5df7261a8219e 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.8E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19795 02c7953ed5715301bef5df7261a8219e 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 2.8E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19795 02c7953ed5715301bef5df7261a8219e 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 2.8E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19795 02c7953ed5715301bef5df7261a8219e 110 SMART SM00418 3 77 5.0E-16 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19795 02c7953ed5715301bef5df7261a8219e 110 SUPERFAMILY SSF46785 1 97 1.87E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19795 02c7953ed5715301bef5df7261a8219e 110 Pfam PF12840 Helix-turn-helix domain 2 61 6.6E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19795 02c7953ed5715301bef5df7261a8219e 110 Gene3D G3DSA:1.10.10.10 1 100 1.4E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 165 1.8E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 Gene3D G3DSA:3.40.50.720 307 435 1.7E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 Gene3D G3DSA:3.40.50.720 1 86 1.7E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 SUPERFAMILY SSF51971 1 202 1.65E-56 T 09-03-2017 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 SUPERFAMILY SSF51971 251 307 1.65E-56 T 09-03-2017 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 Gene3D G3DSA:3.50.50.60 87 306 2.7E-70 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 PRINTS PR00419 Adrenodoxin reductase family signature 22 35 2.9E-9 T 09-03-2017 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 PRINTS PR00419 Adrenodoxin reductase family signature 65 75 2.9E-9 T 09-03-2017 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 PRINTS PR00419 Adrenodoxin reductase family signature 136 150 2.9E-9 T 09-03-2017 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 SUPERFAMILY SSF51971 252 430 4.71E-10 T 09-03-2017 UA74_RS09910 e0f4c44d7fdab1ffa212bcf0e24f1a9e 439 PIRSF PIRSF000362 1 439 1.8E-160 T 09-03-2017 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 UA74_RS14940 b059d7079ea6fc8fc0a460f2e1c675c4 191 Gene3D G3DSA:3.40.630.30 14 188 8.3E-51 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14940 b059d7079ea6fc8fc0a460f2e1c675c4 191 Pfam PF13302 Acetyltransferase (GNAT) domain 20 158 6.7E-32 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS14940 b059d7079ea6fc8fc0a460f2e1c675c4 191 SUPERFAMILY SSF55729 14 182 3.73E-43 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 SUPERFAMILY SSF88659 151 209 3.55E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 Pfam PF04542 Sigma-70 region 2 36 101 1.1E-20 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 SUPERFAMILY SSF88946 16 108 2.04E-29 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 Pfam PF12680 SnoaL-like domain 231 337 7.6E-8 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 Gene3D G3DSA:1.10.10.10 152 210 1.9E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 Gene3D G3DSA:3.10.450.50 225 341 1.8E-14 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 58 89 - T 09-03-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 SUPERFAMILY SSF54427 229 340 3.35E-12 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 29 350 2.7E-105 T 09-03-2017 IPR014305 RNA polymerase sigma-G type, actinobacteria UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 Pfam PF08281 Sigma-70, region 4 154 205 5.0E-13 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 Gene3D G3DSA:1.10.1740.10 16 108 9.4E-35 T 09-03-2017 UA74_RS18635 fe0ff7bf25ee32e0be7cd47e0cbeecb7 376 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 209 1.9E-25 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS19865 62da5446771938380bf3e77365c3ae4a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.3E-13 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19865 62da5446771938380bf3e77365c3ae4a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 1.3E-13 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19865 62da5446771938380bf3e77365c3ae4a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 1.3E-13 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19865 62da5446771938380bf3e77365c3ae4a 116 SUPERFAMILY SSF46785 14 100 4.82E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19865 62da5446771938380bf3e77365c3ae4a 116 Pfam PF12840 Helix-turn-helix domain 26 83 3.8E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19865 62da5446771938380bf3e77365c3ae4a 116 SMART SM00418 25 103 3.8E-22 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19865 62da5446771938380bf3e77365c3ae4a 116 Gene3D G3DSA:1.10.10.10 4 108 1.7E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05135 5a25bbb3229c6db0e8c9fa1b49ff4fa2 316 Gene3D G3DSA:3.90.550.10 6 241 2.3E-34 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS05135 5a25bbb3229c6db0e8c9fa1b49ff4fa2 316 SUPERFAMILY SSF53448 3 216 4.71E-36 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS05135 5a25bbb3229c6db0e8c9fa1b49ff4fa2 316 Pfam PF00535 Glycosyl transferase family 2 9 139 2.2E-20 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 1.6E-16 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 SMART SM00895 87 210 3.6E-6 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 Gene3D G3DSA:1.10.10.10 12 79 4.7E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 SMART SM00345 19 77 6.7E-15 T 09-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 SUPERFAMILY SSF46785 13 81 1.59E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 Gene3D G3DSA:1.20.120.530 81 208 1.9E-16 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 SUPERFAMILY SSF48008 93 213 1.88E-15 T 09-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_RS20510 dd4c4f420b0413eb52112a29bd68d4fe 227 Pfam PF07729 FCD domain 91 206 3.5E-17 T 09-03-2017 IPR011711 GntR, C-terminal UA74_RS29105 a7ddb29229ee19215fbfb09d1de450ac 168 Pfam PF01047 MarR family 39 98 1.4E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29105 a7ddb29229ee19215fbfb09d1de450ac 168 SUPERFAMILY SSF46785 15 143 1.91E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29105 a7ddb29229ee19215fbfb09d1de450ac 168 Gene3D G3DSA:1.10.10.10 13 144 4.8E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29105 a7ddb29229ee19215fbfb09d1de450ac 168 SMART SM00347 32 131 3.6E-15 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29105 a7ddb29229ee19215fbfb09d1de450ac 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.7E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29105 a7ddb29229ee19215fbfb09d1de450ac 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.7E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29105 a7ddb29229ee19215fbfb09d1de450ac 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.7E-5 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS23245 924acc3ccf3cb93a1a156abe1e0e8a7c 243 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 7 202 6.1E-29 T 09-03-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 UA74_RS23245 924acc3ccf3cb93a1a156abe1e0e8a7c 243 Gene3D G3DSA:1.10.3630.10 6 169 1.2E-15 T 09-03-2017 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 285 295 2.0E-23 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 381 402 2.0E-23 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 38 48 2.0E-23 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 121 140 2.0E-23 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 404 416 2.0E-23 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 Pfam PF00083 Sugar (and other) transporter 34 475 1.1E-101 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 22 475 9.3E-105 T 09-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 SUPERFAMILY SSF103473 26 475 2.35E-66 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 Gene3D G3DSA:1.20.1250.20 273 474 6.2E-21 T 09-03-2017 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 Gene3D G3DSA:1.20.1250.20 34 224 6.4E-22 T 09-03-2017 UA74_RS29965 83949196a0233e2129837dc6563bdd56 476 ProSitePatterns PS00216 Sugar transport proteins signature 1. 329 346 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS13125 42e6c730f8dd0cb57bb071129094d82f 253 Pfam PF13490 Putative zinc-finger 15 49 8.7E-6 T 09-03-2017 IPR027383 Putative zinc-finger UA74_RS02115 47632de0b9d425c33e18061926fa712d 390 Gene3D G3DSA:3.20.20.70 23 178 4.3E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS02115 47632de0b9d425c33e18061926fa712d 390 SUPERFAMILY SSF102114 28 140 7.06E-6 T 09-03-2017 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 37 505 1.3E-166 T 09-03-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 SUPERFAMILY SSF56322 27 506 8.77E-153 T 09-03-2017 IPR005801 ADC synthase GO:0009058 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 Pfam PF04715 Anthranilate synthase component I, N terminal region 38 179 8.2E-31 T 09-03-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 Gene3D G3DSA:3.60.120.10 26 509 5.2E-173 T 09-03-2017 IPR005801 ADC synthase GO:0009058 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 Pfam PF00425 chorismate binding enzyme 235 497 9.2E-97 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 439 453 2.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 359 372 2.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 454 468 2.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS10110 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 345 358 2.5E-24 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS10835 23c2020280b8543dc9633b2f6ed13e44 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_RS10835 23c2020280b8543dc9633b2f6ed13e44 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 3.5E-11 T 09-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_RS08940 23627013512843e4f2be01a8e1e3364a 267 SUPERFAMILY SSF75217 2 239 6.34E-88 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS08940 23627013512843e4f2be01a8e1e3364a 267 Gene3D G3DSA:3.40.1280.10 2 166 1.5E-63 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS08940 23627013512843e4f2be01a8e1e3364a 267 PIRSF PIRSF000386 1 257 1.4E-92 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_RS08940 23627013512843e4f2be01a8e1e3364a 267 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 267 103.308 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_RS08940 23627013512843e4f2be01a8e1e3364a 267 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 3.3E-75 T 09-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_RS08940 23627013512843e4f2be01a8e1e3364a 267 Gene3D G3DSA:1.10.1270.20 167 252 2.4E-32 T 09-03-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_RS08940 23627013512843e4f2be01a8e1e3364a 267 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 227 3.9E-66 T 09-03-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_RS04390 b7bd637890a313548922b7cfcd955738 370 SUPERFAMILY SSF55811 152 231 5.38E-22 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS04390 b7bd637890a313548922b7cfcd955738 370 SUPERFAMILY SSF55811 315 355 5.38E-22 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS04390 b7bd637890a313548922b7cfcd955738 370 Gene3D G3DSA:3.90.79.10 154 245 7.0E-22 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS04390 b7bd637890a313548922b7cfcd955738 370 Gene3D G3DSA:3.90.79.10 322 355 7.0E-22 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS04390 b7bd637890a313548922b7cfcd955738 370 Pfam PF00293 NUDIX domain 154 236 2.3E-12 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS04390 b7bd637890a313548922b7cfcd955738 370 PRINTS PR00502 NUDIX hydrolase family signature 181 195 4.1E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS04390 b7bd637890a313548922b7cfcd955738 370 PRINTS PR00502 NUDIX hydrolase family signature 195 210 4.1E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS22305 c2bc452c32ee889dff473bfcb42f9b95 267 SUPERFAMILY SSF52540 6 218 7.5E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22305 c2bc452c32ee889dff473bfcb42f9b95 267 SMART SM00382 26 210 5.3E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS22305 c2bc452c32ee889dff473bfcb42f9b95 267 Gene3D G3DSA:3.40.50.300 2 223 4.5E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22305 c2bc452c32ee889dff473bfcb42f9b95 267 Pfam PF00005 ABC transporter 18 166 9.0E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16640 88c4b6d409cbb94b7513cdbd6dbef270 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 53 2.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS16640 88c4b6d409cbb94b7513cdbd6dbef270 230 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 72 210 3.6E-14 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS16640 88c4b6d409cbb94b7513cdbd6dbef270 230 Gene3D G3DSA:1.10.357.10 3 215 1.2E-40 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS16640 88c4b6d409cbb94b7513cdbd6dbef270 230 SUPERFAMILY SSF48498 74 210 2.78E-18 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS16640 88c4b6d409cbb94b7513cdbd6dbef270 230 SUPERFAMILY SSF46689 7 70 2.87E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13580 a5b6825551b68edd08b80b188d8ec391 496 Gene3D G3DSA:1.20.1250.20 91 270 1.2E-21 T 09-03-2017 UA74_RS13580 a5b6825551b68edd08b80b188d8ec391 496 Gene3D G3DSA:1.20.1250.20 287 473 1.8E-20 T 09-03-2017 UA74_RS13580 a5b6825551b68edd08b80b188d8ec391 496 SUPERFAMILY SSF103473 87 462 1.29E-52 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS13580 a5b6825551b68edd08b80b188d8ec391 496 Pfam PF07690 Major Facilitator Superfamily 96 290 2.8E-18 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS13580 a5b6825551b68edd08b80b188d8ec391 496 Pfam PF07690 Major Facilitator Superfamily 297 476 4.3E-16 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS17485 c7cf86e0d2cb84d5b5b9352bc53ccb5a 231 Gene3D G3DSA:1.10.10.60 29 79 1.5E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17485 c7cf86e0d2cb84d5b5b9352bc53ccb5a 231 Gene3D G3DSA:1.10.357.10 80 229 1.7E-18 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS17485 c7cf86e0d2cb84d5b5b9352bc53ccb5a 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 82 3.4E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS17485 c7cf86e0d2cb84d5b5b9352bc53ccb5a 231 SUPERFAMILY SSF46689 27 106 2.0E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS12580 a30ceb21806af55beb0599b4444f27b9 159 SUPERFAMILY SSF46785 33 145 1.27E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12580 a30ceb21806af55beb0599b4444f27b9 159 SMART SM00418 30 104 0.0082 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS12580 a30ceb21806af55beb0599b4444f27b9 159 Pfam PF12802 MarR family 26 79 9.0E-8 T 09-03-2017 UA74_RS12580 a30ceb21806af55beb0599b4444f27b9 159 Gene3D G3DSA:1.10.10.10 13 82 5.1E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18050 32d4eea3278fcab9d27cd53bfdc5f431 317 Gene3D G3DSA:3.40.50.1820 9 300 4.0E-51 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18050 32d4eea3278fcab9d27cd53bfdc5f431 317 SUPERFAMILY SSF53474 9 300 6.84E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18050 32d4eea3278fcab9d27cd53bfdc5f431 317 Pfam PF00561 alpha/beta hydrolase fold 30 138 2.5E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS08720 ef4c0ee82b739d8bc02c8ce4c7f7a870 442 Gene3D G3DSA:1.20.1250.20 229 412 4.8E-12 T 09-03-2017 UA74_RS08720 ef4c0ee82b739d8bc02c8ce4c7f7a870 442 Gene3D G3DSA:1.20.1250.20 13 204 4.7E-19 T 09-03-2017 UA74_RS08720 ef4c0ee82b739d8bc02c8ce4c7f7a870 442 SUPERFAMILY SSF103473 12 408 4.32E-40 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS08720 ef4c0ee82b739d8bc02c8ce4c7f7a870 442 Pfam PF05977 Transmembrane secretion effector 15 409 1.2E-23 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS08780 eb8c648c969c6b58a4777bd83a81f717 133 PIRSF PIRSF008459 1 133 2.1E-26 T 09-03-2017 IPR016540 Uncharacterised conserved protein UCP008459 UA74_RS08780 eb8c648c969c6b58a4777bd83a81f717 133 SUPERFAMILY SSF55021 66 130 6.54E-17 T 09-03-2017 UA74_RS08780 eb8c648c969c6b58a4777bd83a81f717 133 Gene3D G3DSA:3.30.2130.10 1 128 3.8E-17 T 09-03-2017 UA74_RS08780 eb8c648c969c6b58a4777bd83a81f717 133 Pfam PF13840 ACT domain 64 125 3.0E-18 T 09-03-2017 IPR027795 GATS-like ACT domain UA74_RS08780 eb8c648c969c6b58a4777bd83a81f717 133 SUPERFAMILY SSF55021 1 55 3.02E-9 T 09-03-2017 UA74_RS06870 e06f20ed486a941b7f59b490b56ea96d 186 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 86 5.2E-17 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily UA74_RS06870 e06f20ed486a941b7f59b490b56ea96d 186 SMART SM00226 1 180 2.7E-10 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily UA74_RS06870 e06f20ed486a941b7f59b490b56ea96d 186 SUPERFAMILY SSF52788 1 181 3.27E-24 T 09-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily UA74_RS06870 e06f20ed486a941b7f59b490b56ea96d 186 Gene3D G3DSA:3.40.50.270 1 183 1.7E-28 T 09-03-2017 UA74_RS13565 7cf60454a06ab93bd4d085ae4da5155f 478 Pfam PF00171 Aldehyde dehydrogenase family 8 421 6.2E-33 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS13565 7cf60454a06ab93bd4d085ae4da5155f 478 SUPERFAMILY SSF53720 7 460 7.46E-77 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS13565 7cf60454a06ab93bd4d085ae4da5155f 478 Gene3D G3DSA:3.40.605.10 8 234 4.2E-30 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS13565 7cf60454a06ab93bd4d085ae4da5155f 478 Gene3D G3DSA:3.40.309.10 235 410 2.2E-42 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS07260 2006690cc590250e6964a7e45e9ab06a 325 Pfam PF12079 Protein of unknown function (DUF3558) 4 181 3.0E-8 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS00580 a10edf584af8c2821eba830d08991c23 205 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 198 4.5E-42 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS00580 a10edf584af8c2821eba830d08991c23 205 Gene3D G3DSA:3.40.50.1240 2 199 4.9E-40 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS00580 a10edf584af8c2821eba830d08991c23 205 SUPERFAMILY SSF53254 2 194 1.39E-39 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS00580 a10edf584af8c2821eba830d08991c23 205 SMART SM00855 2 157 2.1E-15 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS00580 a10edf584af8c2821eba830d08991c23 205 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 09-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UA74_RS30465 f50b74c7425e8e3e40fea74ad71203f2 156 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 7 132 2.7E-18 T 09-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UA74_RS30465 f50b74c7425e8e3e40fea74ad71203f2 156 SUPERFAMILY SSF54211 2 133 1.34E-22 T 09-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_RS30465 f50b74c7425e8e3e40fea74ad71203f2 156 Pfam PF00825 Ribonuclease P 2 132 1.1E-27 T 09-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UA74_RS30465 f50b74c7425e8e3e40fea74ad71203f2 156 Gene3D G3DSA:3.30.230.10 2 134 1.4E-32 T 09-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_RS30465 f50b74c7425e8e3e40fea74ad71203f2 156 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 135 17.143 T 09-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 Gene3D G3DSA:1.10.540.10 6 133 3.0E-39 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 383 2.8E-26 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 224 4.4E-23 T 09-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 SUPERFAMILY SSF47203 241 389 2.26E-38 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 SUPERFAMILY SSF56645 9 236 1.01E-73 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 137 149 - T 09-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 131 3.8E-29 T 09-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 Gene3D G3DSA:2.40.110.10 134 225 1.1E-36 T 09-03-2017 UA74_RS29065 04409858c06f5832de985eb34465d2df 391 Gene3D G3DSA:1.20.140.10 226 386 7.4E-38 T 09-03-2017 UA74_RS28560 3d3c89f49e9310275444d336914096de 261 SUPERFAMILY SSF54506 1 259 1.54E-72 T 09-03-2017 UA74_RS28560 3d3c89f49e9310275444d336914096de 261 Gene3D G3DSA:3.10.310.10 123 249 4.6E-40 T 09-03-2017 UA74_RS28560 3d3c89f49e9310275444d336914096de 261 Pfam PF02567 Phenazine biosynthesis-like protein 8 257 2.7E-58 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_RS28560 3d3c89f49e9310275444d336914096de 261 Gene3D G3DSA:3.10.310.10 1 122 5.1E-38 T 09-03-2017 UA74_RS28560 3d3c89f49e9310275444d336914096de 261 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 85 1.0E-23 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_RS28560 3d3c89f49e9310275444d336914096de 261 PIRSF PIRSF016184 1 261 1.7E-49 T 09-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 Gene3D G3DSA:3.40.250.10 4 139 5.6E-37 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 Pfam PF00581 Rhodanese-like domain 149 266 6.6E-17 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 Pfam PF00581 Rhodanese-like domain 9 118 4.0E-15 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 SUPERFAMILY SSF52821 149 274 5.24E-34 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 Gene3D G3DSA:3.40.250.10 149 274 4.2E-34 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 SMART SM00450 8 122 1.4E-21 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 SMART SM00450 144 271 4.5E-20 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 SUPERFAMILY SSF52821 5 139 6.16E-35 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 ProSitePatterns PS00380 Rhodanese signature 1. 34 45 - T 09-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 UA74_RS29315 19f8463e1f1d3f6ca885829bc2685847 282 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 09-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 09-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 SUPERFAMILY SSF103263 2 392 1.16E-129 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 Hamap MF_00300 Chorismate synthase [aroC]. 2 376 33.57 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 09-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 Gene3D G3DSA:3.60.150.10 2 393 8.4E-146 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 Pfam PF01264 Chorismate synthase 2 369 1.1E-112 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 TIGRFAM TIGR00033 aroC: chorismate synthase 2 374 2.3E-119 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS12215 50273662ac04f83293503ec2f821686a 395 PIRSF PIRSF001456 1 386 1.4E-120 T 09-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_RS03745 84181b45b4724377f2b4e0b26d8d79ae 181 Pfam PF04977 Septum formation initiator 69 143 1.3E-12 T 09-03-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 SUPERFAMILY SSF56634 25 544 1.02E-210 T 09-03-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 Pfam PF00199 Catalase 38 424 1.2E-168 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 Pfam PF01965 DJ-1/PfpI family 552 666 6.1E-9 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 Gene3D G3DSA:3.40.50.880 550 720 1.1E-38 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 PIRSF PIRSF038927 7 719 0.0 T 09-03-2017 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 SUPERFAMILY SSF52317 549 718 1.17E-16 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 369 377 - T 09-03-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 SMART SM01060 38 427 2.2E-255 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 ProSitePatterns PS00438 Catalase proximal active site signature. 74 90 - T 09-03-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 51 74 2.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 356 382 2.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 115 133 2.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 324 351 2.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 136 153 2.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 155 173 2.3E-69 T 09-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 Gene3D G3DSA:2.40.180.10 26 394 1.0E-172 T 09-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS13260 e4b989c5d178b356c9147317355d0b4d 721 Pfam PF06628 Catalase-related immune-responsive 455 517 2.2E-21 T 09-03-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 Gene3D G3DSA:3.40.50.1820 4 383 9.7E-132 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 SUPERFAMILY SSF53474 4 380 1.5E-91 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 Pfam PF06441 Epoxide hydrolase N terminus 8 113 3.3E-36 T 09-03-2017 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 PIRSF PIRSF001112 2 384 4.4E-121 T 09-03-2017 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 133 148 4.0E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 179 192 4.0E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 104 122 4.0E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS24430 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 355 377 4.0E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS01330 7753a528219277fe6dbd6c5035d51855 271 Pfam PF14011 EspG family 13 262 8.4E-48 T 09-03-2017 IPR025734 EspG family UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 SUPERFAMILY SSF158472 178 226 1.31E-5 T 09-03-2017 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 SMART SM00388 231 303 7.9E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 3.2E-16 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 SUPERFAMILY SSF47384 214 304 1.26E-13 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 Gene3D G3DSA:1.10.287.130 225 299 4.2E-15 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 302 1.2E-12 T 09-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 SUPERFAMILY SSF55874 305 452 1.96E-37 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 Pfam PF00672 HAMP domain 159 224 8.7E-14 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 451 7.6E-22 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 Gene3D G3DSA:3.30.565.10 305 451 1.5E-40 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 SMART SM00304 178 230 4.1E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS03215 9d8e7d63977228d22f43756e9783759f 455 SMART SM00387 343 454 7.1E-34 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS12925 d12dcbaeb3347d6169439ea8426d3880 277 Gene3D G3DSA:3.40.50.150 71 275 9.0E-64 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12925 d12dcbaeb3347d6169439ea8426d3880 277 PIRSF PIRSF017269 2 272 4.8E-83 T 09-03-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 UA74_RS12925 d12dcbaeb3347d6169439ea8426d3880 277 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 237 6.7E-19 T 09-03-2017 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 UA74_RS12925 d12dcbaeb3347d6169439ea8426d3880 277 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 5 55 3.5E-28 T 09-03-2017 UA74_RS12925 d12dcbaeb3347d6169439ea8426d3880 277 SUPERFAMILY SSF53335 7 260 3.01E-72 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12925 d12dcbaeb3347d6169439ea8426d3880 277 Gene3D G3DSA:3.10.330.20 4 69 1.3E-28 T 09-03-2017 UA74_RS12705 d6df5a0a97768f0f02349cbfee0d67f6 186 Gene3D G3DSA:3.40.50.1820 45 93 1.2E-4 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14150 0a072a402badac3eb3141ee41c0cbbc0 633 SUPERFAMILY SSF53300 446 616 2.82E-16 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS14150 0a072a402badac3eb3141ee41c0cbbc0 633 SMART SM00327 444 626 7.3E-12 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS14150 0a072a402badac3eb3141ee41c0cbbc0 633 Gene3D G3DSA:3.40.50.410 445 589 1.4E-5 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS19890 b1bcb022473db4b9d6955dea6dba6c7d 383 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 91 210 7.9E-26 T 09-03-2017 UA74_RS19890 b1bcb022473db4b9d6955dea6dba6c7d 383 SUPERFAMILY SSF53335 3 209 1.11E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19890 b1bcb022473db4b9d6955dea6dba6c7d 383 Gene3D G3DSA:3.40.50.150 14 244 9.0E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24825 16ff1568b59bc47346cee256a9184aaf 495 SUPERFAMILY SSF117892 67 204 4.58E-24 T 09-03-2017 IPR001107 Band 7 domain UA74_RS24825 16ff1568b59bc47346cee256a9184aaf 495 Pfam PF15975 Flotillin 364 473 5.9E-11 T 09-03-2017 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 UA74_RS24825 16ff1568b59bc47346cee256a9184aaf 495 Pfam PF01145 SPFH domain / Band 7 family 29 215 3.9E-20 T 09-03-2017 IPR001107 Band 7 domain UA74_RS09250 771b590aad906bb88715b188e149d372 462 SUPERFAMILY SSF53790 2 235 1.7E-50 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS09250 771b590aad906bb88715b188e149d372 462 Gene3D G3DSA:3.40.1010.10 3 114 8.2E-24 T 09-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS09250 771b590aad906bb88715b188e149d372 462 Gene3D G3DSA:3.30.950.10 117 236 1.0E-24 T 09-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS09250 771b590aad906bb88715b188e149d372 462 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 09-03-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 UA74_RS09250 771b590aad906bb88715b188e149d372 462 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 213 2.1E-35 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 SMART SM00382 23 211 5.8E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 SMART SM00382 276 472 9.8 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 Gene3D G3DSA:3.40.50.300 248 486 1.8E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 Gene3D G3DSA:3.40.50.300 2 224 1.6E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 SUPERFAMILY SSF52540 2 221 1.61E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 SUPERFAMILY SSF52540 249 483 1.62E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 Pfam PF00005 ABC transporter 15 163 2.6E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13740 0275162b329275347e5482d5967ea1f0 495 Pfam PF00005 ABC transporter 268 423 1.6E-15 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS21455 23ceced77c75cb41b7c3a493247a817d 326 Gene3D G3DSA:3.60.15.10 60 318 1.9E-77 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS21455 23ceced77c75cb41b7c3a493247a817d 326 Pfam PF12706 Beta-lactamase superfamily domain 85 275 1.2E-47 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS21455 23ceced77c75cb41b7c3a493247a817d 326 SUPERFAMILY SSF56281 52 290 4.98E-38 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS09030 a63988312c59e26f6ff5342edf7dcad5 174 Gene3D G3DSA:2.70.70.10 32 165 8.7E-28 T 09-03-2017 UA74_RS09030 a63988312c59e26f6ff5342edf7dcad5 174 Pfam PF01551 Peptidase family M23 66 160 6.0E-17 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS09030 a63988312c59e26f6ff5342edf7dcad5 174 SUPERFAMILY SSF51261 40 164 2.04E-19 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS12445 33f78f1ea7083b87809350988550e969 411 Gene3D G3DSA:3.40.50.1270 197 399 6.3E-84 T 09-03-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 26 36 - T 09-03-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 Gene3D G3DSA:3.40.50.1260 16 196 1.3E-59 T 09-03-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PIRSF PIRSF000724 8 411 1.7E-132 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 185 207 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 120 135 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 208 227 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 21 37 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 387 404 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 330 355 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 42 64 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 155 177 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 363 374 2.5E-76 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 SUPERFAMILY SSF53748 20 411 1.65E-139 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 Pfam PF00162 Phosphoglycerate kinase 22 401 8.9E-143 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12445 33f78f1ea7083b87809350988550e969 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 16 411 40.509 T 09-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS19220 180da2d9c8fc532ecb92c04850c6c713 234 Pfam PF06054 Competence protein CoiA-like family 8 113 1.1E-5 T 09-03-2017 IPR010330 Competence-induced protein CoiA-like UA74_RS14470 4b90e8e3aefa282cca89f01f38f5d7be 412 Gene3D G3DSA:3.30.465.10 69 173 2.0E-26 T 09-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 UA74_RS14470 4b90e8e3aefa282cca89f01f38f5d7be 412 SUPERFAMILY SSF56176 5 174 1.38E-32 T 09-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 UA74_RS14470 4b90e8e3aefa282cca89f01f38f5d7be 412 Gene3D G3DSA:3.30.43.10 6 68 1.9E-8 T 09-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 UA74_RS14470 4b90e8e3aefa282cca89f01f38f5d7be 412 Pfam PF04030 D-arabinono-1,4-lactone oxidase 283 407 3.2E-20 T 09-03-2017 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 UA74_RS14470 4b90e8e3aefa282cca89f01f38f5d7be 412 Pfam PF01565 FAD binding domain 19 145 1.1E-18 T 09-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_RS25495 18ef24fffd3b213e804b3750577a7def 143 Pfam PF11253 Protein of unknown function (DUF3052) 13 137 5.0E-58 T 09-03-2017 IPR021412 Protein of unknown function DUF3052 UA74_RS29490 21870aaa3144dd63c46a2f92daee9fc0 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 4.1E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS29490 21870aaa3144dd63c46a2f92daee9fc0 200 Gene3D G3DSA:1.10.357.10 10 191 2.3E-29 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS29490 21870aaa3144dd63c46a2f92daee9fc0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS29490 21870aaa3144dd63c46a2f92daee9fc0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS29490 21870aaa3144dd63c46a2f92daee9fc0 200 SUPERFAMILY SSF46689 7 78 2.57E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17130 90d9580b81bac78136be9481904e7a45 235 Gene3D G3DSA:3.90.79.10 9 144 3.9E-41 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS17130 90d9580b81bac78136be9481904e7a45 235 Gene3D G3DSA:1.10.10.10 147 220 1.3E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17130 90d9580b81bac78136be9481904e7a45 235 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS17130 90d9580b81bac78136be9481904e7a45 235 Pfam PF00293 NUDIX domain 14 140 1.0E-15 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS17130 90d9580b81bac78136be9481904e7a45 235 SUPERFAMILY SSF55811 12 150 1.62E-27 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS17130 90d9580b81bac78136be9481904e7a45 235 SUPERFAMILY SSF46785 155 226 2.99E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27085 c320bd5823fb5b4a08dd5c2429ff9e66 130 Gene3D G3DSA:3.10.180.10 2 128 3.8E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS27085 c320bd5823fb5b4a08dd5c2429ff9e66 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 125 4.9E-11 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS27085 c320bd5823fb5b4a08dd5c2429ff9e66 130 SUPERFAMILY SSF54593 3 127 1.34E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS08860 1bc42b8f5c1e354a041d5885e026bc0d 141 Gene3D G3DSA:1.10.10.10 2 133 9.0E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08860 1bc42b8f5c1e354a041d5885e026bc0d 141 SUPERFAMILY SSF46785 5 133 1.57E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09745 b105a64557bf644be9caa61b927b3231 281 Gene3D G3DSA:1.10.260.40 5 68 5.7E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09745 b105a64557bf644be9caa61b927b3231 281 Pfam PF13560 Helix-turn-helix domain 10 69 2.7E-13 T 09-03-2017 UA74_RS09745 b105a64557bf644be9caa61b927b3231 281 SMART SM00530 14 69 4.3E-10 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS09745 b105a64557bf644be9caa61b927b3231 281 SUPERFAMILY SSF47413 8 68 2.73E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS14380 f6d55fdba1f86c6c040aeec2e1d0d6bf 64 SUPERFAMILY SSF53098 7 59 1.86E-5 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS14380 f6d55fdba1f86c6c040aeec2e1d0d6bf 64 Pfam PF13683 Integrase core domain 7 52 1.5E-10 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 UA74_RS14380 f6d55fdba1f86c6c040aeec2e1d0d6bf 64 Gene3D G3DSA:3.30.420.10 7 52 4.2E-7 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS20370 e8671306538886ad09150413c764746c 199 Gene3D G3DSA:3.40.50.300 18 163 1.2E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20370 e8671306538886ad09150413c764746c 199 Pfam PF03029 Conserved hypothetical ATP binding protein 24 191 2.0E-22 T 09-03-2017 IPR004130 GPN-loop GTPase UA74_RS20370 e8671306538886ad09150413c764746c 199 SUPERFAMILY SSF52540 18 194 1.08E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03360 7a1884af1c349520c3e4c855df029337 132 SUPERFAMILY SSF55961 3 130 6.05E-12 T 09-03-2017 UA74_RS03360 7a1884af1c349520c3e4c855df029337 132 Gene3D G3DSA:3.30.530.20 7 129 4.5E-9 T 09-03-2017 IPR023393 START-like domain UA74_RS14090 9876b1e6b1a05e97277ea724e27fcdf4 187 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 185 2.2E-21 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_RS14090 9876b1e6b1a05e97277ea724e27fcdf4 187 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 7 185 6.1E-48 T 09-03-2017 IPR017520 Conserved hypothetical protein CHP03086 UA74_RS14090 9876b1e6b1a05e97277ea724e27fcdf4 187 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 129 5.3E-14 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_RS14090 9876b1e6b1a05e97277ea724e27fcdf4 187 SUPERFAMILY SSF109854 2 135 1.45E-22 T 09-03-2017 UA74_RS14090 9876b1e6b1a05e97277ea724e27fcdf4 187 Gene3D G3DSA:1.20.120.450 2 51 2.5E-4 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS19580 23340152a087a6bb1548d5609e8420ea 377 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 16 344 5.2E-132 T 09-03-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 UA74_RS19580 23340152a087a6bb1548d5609e8420ea 377 Pfam PF01758 Sodium Bile acid symporter family 61 257 4.7E-62 T 09-03-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UA74_RS19580 23340152a087a6bb1548d5609e8420ea 377 PIRSF PIRSF005508 2 359 7.8E-136 T 09-03-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 UA74_RS21190 56d49ed04ba18e5669cc6b14f006e940 266 Gene3D G3DSA:3.40.50.150 21 250 1.3E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21190 56d49ed04ba18e5669cc6b14f006e940 266 SUPERFAMILY SSF53335 13 253 1.2E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21190 56d49ed04ba18e5669cc6b14f006e940 266 Pfam PF01209 ubiE/COQ5 methyltransferase family 29 141 8.0E-19 T 09-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_RS15005 b6f3937759d32da43759a75de969a1d2 161 SMART SM00347 36 136 1.7E-14 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS15005 b6f3937759d32da43759a75de969a1d2 161 Gene3D G3DSA:1.10.10.10 7 144 2.6E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15005 b6f3937759d32da43759a75de969a1d2 161 SUPERFAMILY SSF46785 17 144 3.99E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15005 b6f3937759d32da43759a75de969a1d2 161 Pfam PF12802 MarR family 45 100 1.3E-14 T 09-03-2017 UA74_RS27600 af08251a79cf2b824163f5b4e570d992 133 SUPERFAMILY SSF55298 1 133 7.38E-26 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS27600 af08251a79cf2b824163f5b4e570d992 133 Pfam PF01042 Endoribonuclease L-PSP 19 131 1.0E-20 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family UA74_RS27600 af08251a79cf2b824163f5b4e570d992 133 Gene3D G3DSA:3.30.1330.40 1 133 9.8E-33 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS23330 b75237bd4006532abd54cc12a0f86506 220 Gene3D G3DSA:3.30.70.900 5 104 3.1E-17 T 09-03-2017 UA74_RS23330 b75237bd4006532abd54cc12a0f86506 220 Gene3D G3DSA:3.30.70.900 124 193 1.8E-12 T 09-03-2017 UA74_RS23330 b75237bd4006532abd54cc12a0f86506 220 SUPERFAMILY SSF54909 121 186 2.86E-9 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS23330 b75237bd4006532abd54cc12a0f86506 220 SUPERFAMILY SSF54909 42 75 1.88E-5 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS23330 b75237bd4006532abd54cc12a0f86506 220 Pfam PF03992 Antibiotic biosynthesis monooxygenase 132 186 1.2E-4 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS02230 12d30617cf7e81599a935f95d0ca83ca 283 SUPERFAMILY SSF51658 6 275 1.66E-40 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS02230 12d30617cf7e81599a935f95d0ca83ca 283 Pfam PF01261 Xylose isomerase-like TIM barrel 20 227 2.7E-12 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS02230 12d30617cf7e81599a935f95d0ca83ca 283 Gene3D G3DSA:3.20.20.150 2 276 1.0E-39 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS21075 2bfdb547075ed215277a57c06e32d06f 257 Pfam PF13349 Putative adhesin 121 252 3.7E-12 T 09-03-2017 IPR025164 Putative adhesin UA74_RS18870 b3f1e0824870b80e23c88c22f4e0ff1b 296 Gene3D G3DSA:1.10.3720.10 68 293 2.4E-58 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18870 b3f1e0824870b80e23c88c22f4e0ff1b 296 Gene3D G3DSA:1.20.58.370 9 43 6.0E-8 T 09-03-2017 UA74_RS18870 b3f1e0824870b80e23c88c22f4e0ff1b 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 290 2.8E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18870 b3f1e0824870b80e23c88c22f4e0ff1b 296 SUPERFAMILY SSF160964 10 43 2.35E-7 T 09-03-2017 UA74_RS18870 b3f1e0824870b80e23c88c22f4e0ff1b 296 SUPERFAMILY SSF161098 59 285 1.44E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 1.0E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 1.0E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.0E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 1.0E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 SUPERFAMILY SSF53474 8 267 2.63E-47 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23445 927db3e318a4b77aba3356d218801288 273 Pfam PF12146 Serine aminopeptidase, S33 28 223 8.5E-20 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 53 68 1.5E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.5E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 243 265 1.5E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 110 123 1.5E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23445 927db3e318a4b77aba3356d218801288 273 Gene3D G3DSA:3.40.50.1820 9 268 1.6E-46 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 Gene3D G3DSA:3.20.20.140 77 293 1.4E-27 T 09-03-2017 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 77 874 3.1E-189 T 09-03-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 Gene3D G3DSA:1.10.150.280 965 1015 8.6E-4 T 09-03-2017 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 SMART SM00481 77 144 4.6E-26 T 09-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 76 1191 12.703 T 09-03-2017 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 SUPERFAMILY SSF89550 77 284 8.24E-22 T 09-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 Pfam PF14579 Helix-hairpin-helix motif 856 1025 8.3E-22 T 09-03-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 Pfam PF02811 PHP domain 78 249 2.0E-31 T 09-03-2017 IPR004013 PHP domain GO:0003824 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 368 783 4.0E-140 T 09-03-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_RS27820 2c731c96e8fd19f08dc7a48f27356c50 1191 Gene3D G3DSA:2.40.50.140 1095 1165 5.4E-5 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS28690 1f01d4ade9980563adccc8e5f094c913 224 SUPERFAMILY SSF110395 5 221 1.57E-42 T 09-03-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 UA74_RS28690 1f01d4ade9980563adccc8e5f094c913 224 Gene3D G3DSA:3.20.20.380 5 209 4.5E-49 T 09-03-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 UA74_RS28690 1f01d4ade9980563adccc8e5f094c913 224 Pfam PF03932 CutC family 7 198 3.4E-31 T 09-03-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 UA74_RS29255 86b822131340117b879834acb7f045ef 220 Pfam PF01895 PhoU domain 123 204 4.0E-11 T 09-03-2017 IPR026022 PhoU domain UA74_RS29255 86b822131340117b879834acb7f045ef 220 Pfam PF01895 PhoU domain 16 102 1.6E-15 T 09-03-2017 IPR026022 PhoU domain UA74_RS29255 86b822131340117b879834acb7f045ef 220 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 4.6E-53 T 09-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 UA74_RS29255 86b822131340117b879834acb7f045ef 220 PIRSF PIRSF003107 1 217 2.6E-53 T 09-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 UA74_RS29255 86b822131340117b879834acb7f045ef 220 SUPERFAMILY SSF109755 2 213 1.67E-55 T 09-03-2017 UA74_RS29255 86b822131340117b879834acb7f045ef 220 Gene3D G3DSA:1.20.58.220 115 211 1.3E-17 T 09-03-2017 UA74_RS29255 86b822131340117b879834acb7f045ef 220 Gene3D G3DSA:1.20.58.220 1 106 1.3E-26 T 09-03-2017 UA74_RS10430 591c552f68ca7dc6ffef6f7015ac606c 430 Gene3D G3DSA:1.25.40.10 198 283 1.6E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10430 591c552f68ca7dc6ffef6f7015ac606c 430 Gene3D G3DSA:1.25.40.10 298 417 6.4E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10430 591c552f68ca7dc6ffef6f7015ac606c 430 SUPERFAMILY SSF48452 208 412 7.11E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS10430 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 342 375 23.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS10430 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 382 415 190.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS10430 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 215 248 40.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS10430 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 302 335 42.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS23085 f6b2e8d2c3c464d4a34780f38500d067 279 SUPERFAMILY SSF56219 2 253 2.88E-29 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS23085 f6b2e8d2c3c464d4a34780f38500d067 279 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 244 2.4E-14 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS23085 f6b2e8d2c3c464d4a34780f38500d067 279 Gene3D G3DSA:3.60.10.10 1 250 1.8E-32 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS17580 c10d24b44ec136d8ebcc635932591397 282 SUPERFAMILY SSF53474 12 277 5.08E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17580 c10d24b44ec136d8ebcc635932591397 282 Gene3D G3DSA:3.40.50.1820 11 278 3.0E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17580 c10d24b44ec136d8ebcc635932591397 282 Pfam PF00561 alpha/beta hydrolase fold 26 162 1.1E-16 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS18440 8c084654ae90ab312dcf009abbd24aff 104 Pfam PF00754 F5/8 type C domain 7 98 3.7E-7 T 09-03-2017 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_RS18440 8c084654ae90ab312dcf009abbd24aff 104 SUPERFAMILY SSF49785 3 101 4.95E-11 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS18440 8c084654ae90ab312dcf009abbd24aff 104 Gene3D G3DSA:2.60.120.260 2 101 3.8E-13 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS06755 fd0d21c5f85537e601bef910c5f38298 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 8.8E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06755 fd0d21c5f85537e601bef910c5f38298 199 SUPERFAMILY SSF48498 84 194 1.55E-18 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS06755 fd0d21c5f85537e601bef910c5f38298 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06755 fd0d21c5f85537e601bef910c5f38298 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.5E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06755 fd0d21c5f85537e601bef910c5f38298 199 Gene3D G3DSA:1.10.357.10 2 196 8.6E-48 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06755 fd0d21c5f85537e601bef910c5f38298 199 SUPERFAMILY SSF46689 2 69 3.18E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06755 fd0d21c5f85537e601bef910c5f38298 199 Pfam PF13977 Bacterial transcriptional repressor 85 195 1.4E-18 T 09-03-2017 UA74_RS10595 7825b92749fff904cd3ccc7c7fe57375 236 Pfam PF00582 Universal stress protein family 60 218 4.4E-22 T 09-03-2017 IPR006016 UspA GO:0006950 UA74_RS10595 7825b92749fff904cd3ccc7c7fe57375 236 Gene3D G3DSA:3.40.50.620 60 219 1.5E-29 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS10595 7825b92749fff904cd3ccc7c7fe57375 236 SUPERFAMILY SSF52402 61 220 1.17E-26 T 09-03-2017 UA74_RS10595 7825b92749fff904cd3ccc7c7fe57375 236 PRINTS PR01438 Universal stress protein signature 60 78 5.4E-15 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS10595 7825b92749fff904cd3ccc7c7fe57375 236 PRINTS PR01438 Universal stress protein signature 178 190 5.4E-15 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS10595 7825b92749fff904cd3ccc7c7fe57375 236 PRINTS PR01438 Universal stress protein signature 196 218 5.4E-15 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS04915 91339434c35fabbe0527d48989652d69 502 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 90 440 9.5E-114 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 UA74_RS04915 91339434c35fabbe0527d48989652d69 502 Pfam PF10103 Zinicin-like metallopeptidase 90 438 9.1E-112 T 09-03-2017 IPR018766 Zinicin-like metallopeptidase type 2 UA74_RS04915 91339434c35fabbe0527d48989652d69 502 SUPERFAMILY SSF55486 89 440 2.2E-108 T 09-03-2017 UA74_RS09095 0cc82890487fea4f4601730a9bf0791d 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 58 237 5.2E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS09095 0cc82890487fea4f4601730a9bf0791d 255 SUPERFAMILY SSF161098 2 233 2.35E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS09095 0cc82890487fea4f4601730a9bf0791d 255 Gene3D G3DSA:1.10.3720.10 1 244 1.6E-53 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS10135 2f4f8518ceedfaa555cf398a94502061 185 SUPERFAMILY SSF52980 14 151 1.5E-18 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS10135 2f4f8518ceedfaa555cf398a94502061 185 Gene3D G3DSA:3.90.1570.10 16 151 2.9E-16 T 09-03-2017 IPR012296 Nuclease, putative, TT1808 UA74_RS10135 2f4f8518ceedfaa555cf398a94502061 185 Pfam PF05685 Putative restriction endonuclease 23 183 2.7E-20 T 09-03-2017 IPR008538 Domain of unknown function DUF820 UA74_RS13070 beb39808f511c4ea23789cc2abd314ea 212 Pfam PF08241 Methyltransferase domain 28 121 1.2E-16 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS13070 beb39808f511c4ea23789cc2abd314ea 212 Gene3D G3DSA:3.40.50.150 16 121 3.0E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13070 beb39808f511c4ea23789cc2abd314ea 212 SUPERFAMILY SSF53335 6 129 2.61E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12045 4cc98aeb51b79eb42a0a5e18013e1194 400 Gene3D G3DSA:1.20.1250.20 215 383 8.4E-13 T 09-03-2017 UA74_RS12045 4cc98aeb51b79eb42a0a5e18013e1194 400 SUPERFAMILY SSF103473 8 396 1.06E-35 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS12045 4cc98aeb51b79eb42a0a5e18013e1194 400 Pfam PF07690 Major Facilitator Superfamily 233 391 2.0E-10 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS12045 4cc98aeb51b79eb42a0a5e18013e1194 400 Pfam PF07690 Major Facilitator Superfamily 14 220 3.3E-10 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS12045 4cc98aeb51b79eb42a0a5e18013e1194 400 Gene3D G3DSA:1.20.1250.20 9 188 6.1E-15 T 09-03-2017 UA74_RS25050 f0d51f0985cc6f8e60e558e28db76012 269 PIRSF PIRSF000007 1 269 1.1E-117 T 09-03-2017 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 UA74_RS25050 f0d51f0985cc6f8e60e558e28db76012 269 SUPERFAMILY SSF46626 23 135 1.86E-17 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_RS25050 f0d51f0985cc6f8e60e558e28db76012 269 Gene3D G3DSA:1.10.760.10 52 138 6.1E-19 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_RS25050 f0d51f0985cc6f8e60e558e28db76012 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 54 129 9.5E-7 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_RS25050 f0d51f0985cc6f8e60e558e28db76012 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 150 223 1.5E-11 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_RS25050 f0d51f0985cc6f8e60e558e28db76012 269 Gene3D G3DSA:1.10.760.10 150 229 5.9E-18 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_RS25050 f0d51f0985cc6f8e60e558e28db76012 269 SUPERFAMILY SSF46626 135 225 3.01E-27 T 09-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_RS25755 b4102cf233847085069d48f4b129ff1c 35 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 13 35 8.8E-10 T 09-03-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 UA74_RS25755 b4102cf233847085069d48f4b129ff1c 35 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 13 35 7.7E-10 T 09-03-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 UA74_RS14475 25e8722d852d474cb7f7464b9ecb0842 273 Gene3D G3DSA:3.40.710.10 32 265 3.5E-46 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS14475 25e8722d852d474cb7f7464b9ecb0842 273 Pfam PF00144 Beta-lactamase 34 250 1.2E-30 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS14475 25e8722d852d474cb7f7464b9ecb0842 273 SUPERFAMILY SSF56601 8 265 4.15E-53 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 205 2.6E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 123 2.6E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 2.6E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 2.6E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 2.6E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 Gene3D G3DSA:3.40.50.720 18 273 5.8E-60 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 173 201 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 SUPERFAMILY SSF51735 20 274 4.75E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29925 9615838b00f8abad5789da8958f30eb3 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 273 6.4E-40 T 09-03-2017 UA74_RS07220 cb5d62bee52b02f08f21cd7085faea0a 224 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 1 201 4.7E-71 T 09-03-2017 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC UA74_RS07220 cb5d62bee52b02f08f21cd7085faea0a 224 Gene3D G3DSA:1.10.3720.10 2 200 1.4E-43 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07220 cb5d62bee52b02f08f21cd7085faea0a 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 19 200 1.7E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07220 cb5d62bee52b02f08f21cd7085faea0a 224 SUPERFAMILY SSF161098 2 186 5.76E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07220 cb5d62bee52b02f08f21cd7085faea0a 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 2 95 1.0E-22 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 UA74_RS16460 7256b23f459b33b3750023d403c62f50 405 SUPERFAMILY SSF56601 33 374 8.77E-67 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS16460 7256b23f459b33b3750023d403c62f50 405 Pfam PF00144 Beta-lactamase 75 378 3.3E-54 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS16460 7256b23f459b33b3750023d403c62f50 405 Gene3D G3DSA:3.40.710.10 71 374 3.9E-69 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS27450 91b39dbf4a6fbab6fff300dc640ab06e 201 Gene3D G3DSA:1.10.357.10 3 189 6.4E-41 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS27450 91b39dbf4a6fbab6fff300dc640ab06e 201 SUPERFAMILY SSF48498 84 190 1.19E-23 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS27450 91b39dbf4a6fbab6fff300dc640ab06e 201 Pfam PF13305 WHG domain 89 172 2.6E-14 T 09-03-2017 IPR025996 WHG domain UA74_RS27450 91b39dbf4a6fbab6fff300dc640ab06e 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.5E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS27450 91b39dbf4a6fbab6fff300dc640ab06e 201 SUPERFAMILY SSF46689 3 86 2.57E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS01345 9367dc2baee650421f7f40691ac65130 601 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 50 389 2.4E-106 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01345 9367dc2baee650421f7f40691ac65130 601 Gene3D G3DSA:3.20.20.300 83 414 1.3E-107 T 09-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_RS01345 9367dc2baee650421f7f40691ac65130 601 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 431 597 5.8E-10 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS01345 9367dc2baee650421f7f40691ac65130 601 Gene3D G3DSA:3.40.50.1700 415 596 4.2E-13 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS01345 9367dc2baee650421f7f40691ac65130 601 SUPERFAMILY SSF52279 431 598 3.79E-13 T 09-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_RS01345 9367dc2baee650421f7f40691ac65130 601 SUPERFAMILY SSF51445 34 424 6.21E-102 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS10605 350ed0ec8d5c6811ef76ddb627a9f402 189 Gene3D G3DSA:1.10.10.60 9 38 7.9E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS10605 350ed0ec8d5c6811ef76ddb627a9f402 189 SUPERFAMILY SSF46689 6 44 6.48E-9 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS10605 350ed0ec8d5c6811ef76ddb627a9f402 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 6 36 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS10605 350ed0ec8d5c6811ef76ddb627a9f402 189 Gene3D G3DSA:1.10.357.10 39 174 8.0E-13 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS10605 350ed0ec8d5c6811ef76ddb627a9f402 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 39 1.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS10605 350ed0ec8d5c6811ef76ddb627a9f402 189 SUPERFAMILY SSF48498 67 166 1.76E-8 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS12965 4ae2418dc3321d7c1d36dfe3138b1d43 318 Gene3D G3DSA:3.20.20.100 9 301 9.9E-31 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS12965 4ae2418dc3321d7c1d36dfe3138b1d43 318 Pfam PF00248 Aldo/keto reductase family 47 298 1.9E-20 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS12965 4ae2418dc3321d7c1d36dfe3138b1d43 318 SUPERFAMILY SSF51430 8 302 1.1E-35 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS02375 c7d550f3dad9e5195de73781084de512 286 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 20 46 1.7E-6 T 09-03-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 UA74_RS02375 c7d550f3dad9e5195de73781084de512 286 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 85 265 1.9E-30 T 09-03-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 Pfam PF13229 Right handed beta helix region 382 532 5.0E-14 T 09-03-2017 UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 Gene3D G3DSA:2.160.20.10 373 531 9.6E-17 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 Gene3D G3DSA:2.160.20.10 2 126 9.6E-17 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 358 380 10000.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 290 312 760.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 459 486 2500.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 493 518 1800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 382 404 15.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 433 455 31.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 405 432 8100.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SUPERFAMILY SSF51126 3 103 2.49E-25 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SUPERFAMILY SSF51126 373 556 2.49E-25 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS28530 ff89652ff1a7404f16e15211097ddd9e 607 SUPERFAMILY SSF51126 280 304 2.49E-25 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS23885 caf37c1aaa3ee5eebc647337df3f4a79 285 SUPERFAMILY SSF161098 9 285 3.66E-73 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23885 caf37c1aaa3ee5eebc647337df3f4a79 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 278 2.7E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23885 caf37c1aaa3ee5eebc647337df3f4a79 285 Gene3D G3DSA:1.10.3720.10 4 272 3.5E-66 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 Gene3D G3DSA:1.10.10.10 157 222 7.7E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 Pfam PF00072 Response regulator receiver domain 11 107 1.3E-12 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 SUPERFAMILY SSF52172 7 142 5.27E-20 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 8.6E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 8.6E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 8.6E-8 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 SMART SM00421 156 218 8.2E-9 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 Gene3D G3DSA:3.40.50.2300 8 156 7.3E-24 T 09-03-2017 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 SUPERFAMILY SSF46894 140 206 3.27E-12 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 SMART SM00448 9 128 1.5E-10 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS04295 4b5e4526b577e3db8addcf3e10bd10cf 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 203 1.0E-10 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 621 3.2E-246 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 Pfam PF13522 Glutamine amidotransferase domain 65 202 7.6E-22 T 09-03-2017 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 SUPERFAMILY SSF53697 254 621 1.11E-105 T 09-03-2017 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 Gene3D G3DSA:3.40.50.10490 451 621 9.7E-61 T 09-03-2017 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 Pfam PF01380 SIS domain 298 422 8.2E-32 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 Pfam PF01380 SIS domain 470 599 3.9E-21 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 621 40.563 T 09-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 Gene3D G3DSA:3.60.20.10 2 249 1.0E-75 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 Gene3D G3DSA:3.40.50.10490 253 450 1.9E-70 T 09-03-2017 UA74_RS28175 bcc17b0db01280ba92ee7d7843796290 621 SUPERFAMILY SSF56235 2 240 1.72E-67 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS21395 194e5b443b3fb345fea06eb3a42fafed 280 Gene3D G3DSA:3.40.50.80 139 275 5.7E-43 T 09-03-2017 UA74_RS21395 194e5b443b3fb345fea06eb3a42fafed 280 SUPERFAMILY SSF63380 10 139 8.7E-14 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS21395 194e5b443b3fb345fea06eb3a42fafed 280 Pfam PF04954 Siderophore-interacting protein 144 264 8.6E-37 T 09-03-2017 IPR007037 Siderophore-interacting protein UA74_RS21395 194e5b443b3fb345fea06eb3a42fafed 280 Gene3D G3DSA:2.40.30.10 13 135 5.8E-34 T 09-03-2017 UA74_RS21395 194e5b443b3fb345fea06eb3a42fafed 280 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 136 5.5E-34 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting UA74_RS23560 9ae29e6225126dac7b5fc38b5ff4602f 176 Pfam PF04343 Protein of unknown function, DUF488 15 134 1.3E-25 T 09-03-2017 IPR007438 Protein of unknown function DUF488 UA74_RS23560 9ae29e6225126dac7b5fc38b5ff4602f 176 PIRSF PIRSF024492 1 175 1.1E-42 T 09-03-2017 IPR014519 Uncharacterised conserved protein UCP024492 UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 2.5E-58 T 09-03-2017 UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 Gene3D G3DSA:3.40.50.720 2 249 2.3E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 186 1.5E-4 T 09-03-2017 UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 SUPERFAMILY SSF51735 2 249 8.95E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.0E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.0E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS15240 75a350715b027bd92c64b03b237fedea 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.0E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20950 c5b4f3a285b26db1942de88d98f02adc 169 SMART SM00418 5 86 0.0018 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS20950 c5b4f3a285b26db1942de88d98f02adc 169 Gene3D G3DSA:1.10.10.10 5 74 2.3E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20950 c5b4f3a285b26db1942de88d98f02adc 169 SUPERFAMILY SSF46785 3 149 1.78E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20950 c5b4f3a285b26db1942de88d98f02adc 169 Pfam PF12840 Helix-turn-helix domain 7 63 2.5E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26195 6911ff403c067c3d7d5439303bd19acf 335 Pfam PF00561 alpha/beta hydrolase fold 26 129 1.4E-6 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS26195 6911ff403c067c3d7d5439303bd19acf 335 Gene3D G3DSA:3.40.50.1820 23 300 1.6E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26195 6911ff403c067c3d7d5439303bd19acf 335 SUPERFAMILY SSF53474 5 139 9.58E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26195 6911ff403c067c3d7d5439303bd19acf 335 SUPERFAMILY SSF53474 177 298 9.58E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26600 ba8c457bef18f5ed6fafa8e7590b97d8 201 Gene3D G3DSA:3.40.50.1240 14 199 7.7E-48 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS26600 ba8c457bef18f5ed6fafa8e7590b97d8 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 14 199 2.5E-49 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS26600 ba8c457bef18f5ed6fafa8e7590b97d8 201 SUPERFAMILY SSF53254 14 199 2.49E-50 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS26600 ba8c457bef18f5ed6fafa8e7590b97d8 201 SMART SM00855 13 161 4.3E-20 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS00620 7f5724038f9aad5a564752eaebafbcac 295 Pfam PF00296 Luciferase-like monooxygenase 21 232 6.7E-43 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS00620 7f5724038f9aad5a564752eaebafbcac 295 SUPERFAMILY SSF51679 19 292 1.96E-52 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS00620 7f5724038f9aad5a564752eaebafbcac 295 Gene3D G3DSA:3.20.20.30 20 291 4.8E-59 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS12020 1c875f794e78d1cf33473dba4aeadabb 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.1E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS12020 1c875f794e78d1cf33473dba4aeadabb 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.1E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS12020 1c875f794e78d1cf33473dba4aeadabb 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.1E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS12020 1c875f794e78d1cf33473dba4aeadabb 127 SMART SM00422 1 69 8.2E-17 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS12020 1c875f794e78d1cf33473dba4aeadabb 127 SUPERFAMILY SSF46955 1 113 3.41E-24 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS12020 1c875f794e78d1cf33473dba4aeadabb 127 Pfam PF13411 MerR HTH family regulatory protein 1 64 4.2E-17 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS12020 1c875f794e78d1cf33473dba4aeadabb 127 Gene3D G3DSA:1.10.1660.10 1 120 1.5E-28 T 09-03-2017 UA74_RS24235 f9339b595335a5effd83e6947fb677bf 133 SUPERFAMILY SSF54593 1 128 1.34E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS24235 f9339b595335a5effd83e6947fb677bf 133 Gene3D G3DSA:3.10.180.10 2 130 9.1E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 SUPERFAMILY SSF88946 5 90 7.85E-10 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 Pfam PF04542 Sigma-70 region 2 17 77 1.7E-6 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 1.3E-18 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 Pfam PF08281 Sigma-70, region 4 103 156 4.6E-16 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 Gene3D G3DSA:1.10.1740.10 5 78 4.7E-11 T 09-03-2017 UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 162 1.1E-48 T 09-03-2017 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 SUPERFAMILY SSF88659 102 159 8.04E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS07185 8238197a3ac52a424e4eda9a71ee0482 188 Gene3D G3DSA:1.10.10.10 102 161 1.3E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22315 9b57e769a6538518a930c1a3a1cb221b 327 Gene3D G3DSA:3.40.50.20 12 113 1.6E-6 T 09-03-2017 IPR016185 Pre-ATP-grasp domain UA74_RS22315 9b57e769a6538518a930c1a3a1cb221b 327 Gene3D G3DSA:3.30.470.20 179 274 3.8E-16 T 09-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 UA74_RS22315 9b57e769a6538518a930c1a3a1cb221b 327 Gene3D G3DSA:3.30.1490.20 114 178 2.7E-7 T 09-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 UA74_RS22315 9b57e769a6538518a930c1a3a1cb221b 327 Pfam PF08443 RimK-like ATP-grasp domain 102 279 6.9E-14 T 09-03-2017 IPR013651 ATP-grasp fold, RimK-type UA74_RS22315 9b57e769a6538518a930c1a3a1cb221b 327 SUPERFAMILY SSF56059 92 281 6.9E-29 T 09-03-2017 UA74_RS12160 a5051e7add88d7b70e2cdef5f66eafee 106 Pfam PF04149 Domain of unknown function (DUF397) 52 102 4.6E-21 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS12160 a5051e7add88d7b70e2cdef5f66eafee 106 Pfam PF04149 Domain of unknown function (DUF397) 10 28 1.1E-5 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS12160 a5051e7add88d7b70e2cdef5f66eafee 106 Pfam PF04149 Domain of unknown function (DUF397) 31 48 3.4E-5 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS14985 e0b97f30851b5ce9bc33554b436c7bce 209 Gene3D G3DSA:2.30.110.10 27 152 7.1E-31 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS14985 e0b97f30851b5ce9bc33554b436c7bce 209 SUPERFAMILY SSF50475 39 154 1.43E-21 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS14985 e0b97f30851b5ce9bc33554b436c7bce 209 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 208 5.5E-73 T 09-03-2017 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent UA74_RS14985 e0b97f30851b5ce9bc33554b436c7bce 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 127 2.0E-16 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS16730 cdd4d66b44cf52061373d1ddb0461b27 272 Gene3D G3DSA:3.40.50.300 12 247 1.1E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16730 cdd4d66b44cf52061373d1ddb0461b27 272 SMART SM00382 33 220 1.6E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16730 cdd4d66b44cf52061373d1ddb0461b27 272 Pfam PF00005 ABC transporter 24 173 4.1E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16730 cdd4d66b44cf52061373d1ddb0461b27 272 SUPERFAMILY SSF52540 7 235 2.27E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.5E-17 T 09-03-2017 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 1.5E-17 T 09-03-2017 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.5E-17 T 09-03-2017 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 SUPERFAMILY SSF51905 4 311 3.42E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 67 77 2.0E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 2.0E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 2.0E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 2.0E-15 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 296 4.7E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 Gene3D G3DSA:3.50.50.60 148 194 8.8E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 Gene3D G3DSA:3.50.50.60 6 144 3.4E-25 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 Gene3D G3DSA:3.50.50.60 195 317 7.3E-21 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04130 d9ef3856e4bc5adb1e73e8374d829466 328 Hamap MF_01685 Ferredoxin--NADP reductase. 8 328 37.204 T 09-03-2017 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 UA74_RS09230 0b22c91f2cc3e4b1f796bc30b947e0a7 98 Gene3D G3DSA:3.30.70.900 2 91 3.5E-13 T 09-03-2017 UA74_RS09230 0b22c91f2cc3e4b1f796bc30b947e0a7 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 2.2E-12 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS09230 0b22c91f2cc3e4b1f796bc30b947e0a7 98 SUPERFAMILY SSF54909 1 93 2.61E-13 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS30190 05363b05783393eb12eba11a2285b915 172 Pfam PF05534 HicB family 109 139 9.0E-6 T 09-03-2017 IPR008651 Uncharacterised protein family HicB UA74_RS30190 05363b05783393eb12eba11a2285b915 172 SUPERFAMILY SSF47598 105 150 2.22E-12 T 09-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 UA74_RS30190 05363b05783393eb12eba11a2285b915 172 Gene3D G3DSA:1.10.1220.10 108 154 3.6E-14 T 09-03-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 UA74_RS18785 3d8bb1776e12991d724c867444e84b21 426 SUPERFAMILY SSF51569 152 409 1.05E-26 T 09-03-2017 UA74_RS18785 3d8bb1776e12991d724c867444e84b21 426 SMART SM01130 144 419 3.4E-8 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS18785 3d8bb1776e12991d724c867444e84b21 426 Pfam PF00701 Dihydrodipicolinate synthetase family 183 401 2.1E-8 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS18785 3d8bb1776e12991d724c867444e84b21 426 Gene3D G3DSA:3.20.20.70 152 418 3.6E-41 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS18785 3d8bb1776e12991d724c867444e84b21 426 Gene3D G3DSA:3.20.20.70 20 56 1.4E-4 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS03635 7ff2a34d230f6ac20c33574b7e95adfd 431 Pfam PF01566 Natural resistance-associated macrophage protein 41 396 1.1E-28 T 09-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 UA74_RS14530 139f4356423e7aee57b4afd4c2500d9a 206 SUPERFAMILY SSF55821 1 204 4.88E-57 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain UA74_RS14530 139f4356423e7aee57b4afd4c2500d9a 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 8.7E-53 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 UA74_RS14530 139f4356423e7aee57b4afd4c2500d9a 206 Gene3D G3DSA:3.90.870.10 2 204 8.4E-57 T 09-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain UA74_RS14530 139f4356423e7aee57b4afd4c2500d9a 206 Pfam PF01300 Telomere recombination 23 198 5.0E-39 T 09-03-2017 IPR006070 YrdC-like domain GO:0003725 UA74_RS05755 3461adcf8c5fa1fccd2e0caceae64266 201 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 178 8.9E-50 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_RS05755 3461adcf8c5fa1fccd2e0caceae64266 201 SUPERFAMILY SSF51182 1 196 5.18E-63 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS05755 3461adcf8c5fa1fccd2e0caceae64266 201 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 6.0E-63 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_RS05755 3461adcf8c5fa1fccd2e0caceae64266 201 Gene3D G3DSA:2.60.120.10 1 189 1.4E-57 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS04605 4e0cb46749310f53b6453a8355e66f88 385 Gene3D G3DSA:3.40.50.2000 162 361 9.1E-53 T 09-03-2017 UA74_RS04605 4e0cb46749310f53b6453a8355e66f88 385 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 2 381 7.8E-179 T 09-03-2017 IPR011875 Glycogen synthase, corynebacterial KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 UA74_RS04605 4e0cb46749310f53b6453a8355e66f88 385 Pfam PF00534 Glycosyl transferases group 1 191 361 6.1E-31 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS04605 4e0cb46749310f53b6453a8355e66f88 385 SUPERFAMILY SSF53756 8 383 8.37E-85 T 09-03-2017 UA74_RS04605 4e0cb46749310f53b6453a8355e66f88 385 Pfam PF13439 Glycosyltransferase Family 4 15 176 2.9E-31 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS25900 c38bdb32aeaca8351a3bc87bf2f88728 223 SUPERFAMILY SSF48371 6 221 1.99E-60 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 UA74_RS25900 c38bdb32aeaca8351a3bc87bf2f88728 223 Pfam PF08713 DNA alkylation repair enzyme 10 197 2.4E-20 T 09-03-2017 IPR014825 DNA alkylation repair enzyme UA74_RS20680 c671c799b862ab172bd2b0e19e8f222e 286 Gene3D G3DSA:3.40.50.720 7 218 1.7E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20680 c671c799b862ab172bd2b0e19e8f222e 286 SUPERFAMILY SSF51735 6 246 6.32E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20680 c671c799b862ab172bd2b0e19e8f222e 286 Pfam PF13460 NAD(P)H-binding 11 185 5.2E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20880 32c7a6065dc9e404491aaf2fca644d63 237 Pfam PF00005 ABC transporter 29 179 7.5E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20880 32c7a6065dc9e404491aaf2fca644d63 237 Gene3D G3DSA:3.40.50.300 9 231 6.8E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20880 32c7a6065dc9e404491aaf2fca644d63 237 SUPERFAMILY SSF52540 9 231 1.15E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20880 32c7a6065dc9e404491aaf2fca644d63 237 SMART SM00382 38 227 8.6E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS20880 32c7a6065dc9e404491aaf2fca644d63 237 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 SUPERFAMILY SSF103473 264 470 6.54E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 SUPERFAMILY SSF103473 14 211 6.54E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 433 2.6E-81 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 Pfam PF07690 Major Facilitator Superfamily 30 426 2.2E-44 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 2.7E-8 T 09-03-2017 UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 2.7E-8 T 09-03-2017 UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 2.7E-8 T 09-03-2017 UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 Gene3D G3DSA:1.20.1250.20 23 206 3.2E-30 T 09-03-2017 UA74_RS17365 f191faf953562c72fc1bfda9f843ac37 470 Gene3D G3DSA:1.20.1250.20 284 470 8.7E-16 T 09-03-2017 UA74_RS01460 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_RS01460 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 SUPERFAMILY SSF46785 27 161 1.67E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01460 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 SMART SM00347 47 146 7.3E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS01460 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 Pfam PF12802 MarR family 58 110 4.8E-14 T 09-03-2017 UA74_RS01460 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 Gene3D G3DSA:1.10.10.10 29 160 2.8E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26245 9f4f44a228201c3966d1e1808619d987 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.608 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UA74_RS26245 9f4f44a228201c3966d1e1808619d987 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 1.5E-15 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UA74_RS26245 9f4f44a228201c3966d1e1808619d987 99 SUPERFAMILY SSF141000 3 94 1.14E-27 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UA74_RS26245 9f4f44a228201c3966d1e1808619d987 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.4E-22 T 09-03-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 SUPERFAMILY SSF46955 1 112 5.13E-28 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 Gene3D G3DSA:1.10.1660.10 1 113 1.5E-31 T 09-03-2017 UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 SMART SM00422 1 69 1.4E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 Pfam PF13411 MerR HTH family regulatory protein 1 67 6.3E-17 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.0E-9 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.0E-9 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS15450 0a6d4708336cc1f4f0478ab99a370f83 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.0E-9 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS16415 d2f2c24aa011a4ed4453e895ddbbde6d 630 Pfam PF07591 Pretoxin HINT domain 398 532 5.2E-20 T 09-03-2017 UA74_RS16415 d2f2c24aa011a4ed4453e895ddbbde6d 630 SUPERFAMILY SSF51294 390 530 3.79E-20 T 09-03-2017 IPR028992 Hedgehog/Intein (Hint) domain UA74_RS16415 d2f2c24aa011a4ed4453e895ddbbde6d 630 Gene3D G3DSA:2.170.16.10 387 540 1.8E-29 T 09-03-2017 IPR028992 Hedgehog/Intein (Hint) domain UA74_RS16415 d2f2c24aa011a4ed4453e895ddbbde6d 630 SMART SM00306 387 489 6.5E-14 T 09-03-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS16415 d2f2c24aa011a4ed4453e895ddbbde6d 630 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 507 532 0.0057 T 09-03-2017 IPR030934 Intein C-terminal splicing region UA74_RS16415 d2f2c24aa011a4ed4453e895ddbbde6d 630 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 108 187 1.5E-18 T 09-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 UA74_RS00320 8e83f6bd51838aacae3103e0483fa68c 224 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 47 210 37.236 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_RS00320 8e83f6bd51838aacae3103e0483fa68c 224 Pfam PF01625 Peptide methionine sulfoxide reductase 49 204 2.6E-67 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_RS00320 8e83f6bd51838aacae3103e0483fa68c 224 Gene3D G3DSA:3.30.1060.10 12 204 1.8E-78 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_RS00320 8e83f6bd51838aacae3103e0483fa68c 224 SUPERFAMILY SSF55068 15 214 1.96E-78 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_RS00320 8e83f6bd51838aacae3103e0483fa68c 224 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 49 204 6.2E-65 T 09-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_RS24000 edcf90f69f8b2833a5d9e89925b5e2f2 102 Pfam PF02575 YbaB/EbfC DNA-binding family 14 93 2.8E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS24000 edcf90f69f8b2833a5d9e89925b5e2f2 102 SUPERFAMILY SSF82607 13 95 2.22E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS24000 edcf90f69f8b2833a5d9e89925b5e2f2 102 Gene3D G3DSA:3.30.1310.10 7 99 8.9E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 SUPERFAMILY SSF55347 144 229 3.49E-29 T 09-03-2017 UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 SUPERFAMILY SSF55347 284 336 3.49E-29 T 09-03-2017 UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 Gene3D G3DSA:3.30.360.10 285 333 2.6E-51 T 09-03-2017 UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 Gene3D G3DSA:3.30.360.10 380 438 2.6E-51 T 09-03-2017 UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 Gene3D G3DSA:3.30.360.10 149 228 2.6E-51 T 09-03-2017 UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 151 227 3.4E-16 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 Gene3D G3DSA:3.40.50.720 9 148 7.5E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 138 2.6E-17 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS23970 d8333b8ef4b0894485093a73b27e4dcb 444 SUPERFAMILY SSF51735 9 170 6.63E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 78 94 - T 09-03-2017 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PRINTS PR00733 Glycosyl hydrolase family 6 signature 158 171 5.2E-30 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PRINTS PR00733 Glycosyl hydrolase family 6 signature 188 198 5.2E-30 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PRINTS PR00733 Glycosyl hydrolase family 6 signature 237 257 5.2E-30 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PRINTS PR00733 Glycosyl hydrolase family 6 signature 73 86 5.2E-30 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PRINTS PR00733 Glycosyl hydrolase family 6 signature 223 236 5.2E-30 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PRINTS PR00733 Glycosyl hydrolase family 6 signature 34 53 5.2E-30 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PRINTS PR00733 Glycosyl hydrolase family 6 signature 261 275 5.2E-30 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 Pfam PF01341 Glycosyl hydrolases family 6 40 279 1.9E-63 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 PIRSF PIRSF001100 1 299 1.5E-76 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 SUPERFAMILY SSF51989 15 297 2.22E-72 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS28950 d0f017a5e0aab5c033c28b091f9fe9f3 300 Gene3D G3DSA:3.20.20.40 16 298 2.9E-77 T 09-03-2017 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_RS01750 73c55037b61a5024451596128cf181a0 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 291 1.6E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01750 73c55037b61a5024451596128cf181a0 300 Gene3D G3DSA:1.10.3720.10 20 287 1.1E-67 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01750 73c55037b61a5024451596128cf181a0 300 SUPERFAMILY SSF161098 24 300 1.68E-68 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08980 2d02e8da2380f02e2f0d43dea98ef108 266 SUPERFAMILY SSF161098 42 221 2.88E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08980 2d02e8da2380f02e2f0d43dea98ef108 266 Gene3D G3DSA:1.10.3720.10 40 239 3.5E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08980 2d02e8da2380f02e2f0d43dea98ef108 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 251 1.2E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS13480 217cb29830123864f3e71220c2b300e8 148 Pfam PF04075 Domain of unknown function (DUF385) 19 147 1.2E-35 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS13480 217cb29830123864f3e71220c2b300e8 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 34 146 5.1E-32 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 Gene3D G3DSA:3.40.50.1820 2 357 5.2E-135 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 SUPERFAMILY SSF53474 2 357 1.54E-99 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 Pfam PF06441 Epoxide hydrolase N terminus 2 107 1.4E-38 T 09-03-2017 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 PIRSF PIRSF001112 1 360 2.1E-108 T 09-03-2017 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 162 175 1.2E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 176 189 1.2E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 301 317 1.2E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 332 354 1.2E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS20180 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 98 116 1.2E-9 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 273 284 2.0E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 340 349 2.0E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 349 360 2.0E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 238 255 2.0E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 Pfam PF00067 Cytochrome P450 86 370 3.4E-28 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 SUPERFAMILY SSF48264 9 400 1.28E-98 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 140 156 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 194 216 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 93 104 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 273 284 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 291 318 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 157 172 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 319 334 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 340 349 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 349 360 7.0E-60 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS05945 aec8b2acd4cf00de609d08bb239b4a47 400 Gene3D G3DSA:1.10.630.10 6 400 2.0E-120 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS25680 222b5954550c25e47caaaea083450f49 500 Pfam PF00474 Sodium:solute symporter family 33 436 7.9E-34 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS25680 222b5954550c25e47caaaea083450f49 500 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 439 9.5E-64 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS01150 43d59c69823d9698771b3127328effea 249 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 12 228 7.1E-26 T 09-03-2017 UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 Pfam PF13378 Enolase C-terminal domain-like 201 385 6.5E-41 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 SMART SM00922 129 265 1.1E-17 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 SUPERFAMILY SSF54826 1 112 3.68E-31 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 Gene3D G3DSA:3.20.20.120 120 373 3.1E-80 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 SUPERFAMILY SSF51604 98 394 7.75E-71 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 5.7E-31 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS18880 b9985912a98dfa31e6d4be0e5d7b917b 410 Gene3D G3DSA:3.30.390.10 1 119 4.5E-44 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS26455 83f8900dd22ca65b1626ed934382db35 410 Gene3D G3DSA:3.40.50.300 4 224 3.4E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26455 83f8900dd22ca65b1626ed934382db35 410 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS26455 83f8900dd22ca65b1626ed934382db35 410 SUPERFAMILY SSF52540 5 225 8.22E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26455 83f8900dd22ca65b1626ed934382db35 410 SMART SM00382 32 210 7.9E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26455 83f8900dd22ca65b1626ed934382db35 410 Pfam PF00005 ABC transporter 24 162 2.3E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS00535 d46490acb2753a71d0025ae8466c08b9 521 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 475 1.9E-164 T 09-03-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 UA74_RS00535 d46490acb2753a71d0025ae8466c08b9 521 PIRSF PIRSF006446 1 489 4.2E-132 T 09-03-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 SUPERFAMILY SSF102114 507 838 1.1E-45 T 09-03-2017 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 Gene3D G3DSA:3.20.20.70 32 360 9.5E-70 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 Gene3D G3DSA:3.20.20.70 504 842 8.6E-73 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 535 847 9.5E-109 T 09-03-2017 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 SUPERFAMILY SSF102114 36 374 1.24E-38 T 09-03-2017 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 SMART SM00729 539 768 0.0061 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 SMART SM00729 76 310 2.1E-7 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 Pfam PF04055 Radical SAM superfamily 543 714 7.6E-15 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 Pfam PF04055 Radical SAM superfamily 80 257 3.2E-11 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 Hamap MF_01612 FO synthase subunit 2 [cofH]. 478 851 48.734 T 09-03-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 Hamap MF_01611 FO synthase subunit 1 [cofG]. 72 404 49.514 T 09-03-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 73 402 7.7E-143 T 09-03-2017 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 UA74_RS17960 cbaff1548a92ecde6edc848125699513 875 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 503 850 3.1E-152 T 09-03-2017 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 UA74_RS19475 0e0050d3a0bd5feb218137cd4836557a 283 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 246 267 1.6E-7 T 09-03-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 UA74_RS22500 1c92b083b04a70e85b3faf8274606c2d 382 Gene3D G3DSA:1.10.357.10 11 208 1.1E-22 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22500 1c92b083b04a70e85b3faf8274606c2d 382 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22500 1c92b083b04a70e85b3faf8274606c2d 382 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22500 1c92b083b04a70e85b3faf8274606c2d 382 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.1E-13 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22500 1c92b083b04a70e85b3faf8274606c2d 382 SUPERFAMILY SSF46689 4 71 2.82E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06105 4e822f14c1400754880e4c74745f551f 205 Gene3D G3DSA:1.10.357.10 10 201 6.6E-22 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06105 4e822f14c1400754880e4c74745f551f 205 SUPERFAMILY SSF46689 4 66 4.04E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06105 4e822f14c1400754880e4c74745f551f 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 58 8.9E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS06105 4e822f14c1400754880e4c74745f551f 205 SUPERFAMILY SSF48498 82 197 1.47E-13 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS15340 c3f9e7209d049bdef2a0237b87f26d53 136 Gene3D G3DSA:3.10.180.10 2 134 6.3E-29 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15340 c3f9e7209d049bdef2a0237b87f26d53 136 SUPERFAMILY SSF54593 5 134 4.03E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15340 c3f9e7209d049bdef2a0237b87f26d53 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 4.6E-15 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS13620 deb4af19439e4ceb13b540e773af88ea 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 220 241 1.0E-8 T 09-03-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal UA74_RS13620 deb4af19439e4ceb13b540e773af88ea 241 Pfam PF00005 ABC transporter 11 171 1.5E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13620 deb4af19439e4ceb13b540e773af88ea 241 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13620 deb4af19439e4ceb13b540e773af88ea 241 SMART SM00382 20 220 5.0E-5 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13620 deb4af19439e4ceb13b540e773af88ea 241 Gene3D G3DSA:3.40.50.300 1 239 4.7E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13620 deb4af19439e4ceb13b540e773af88ea 241 SUPERFAMILY SSF52540 1 240 8.54E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.4E-21 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 Gene3D G3DSA:1.10.10.10 1 84 2.2E-28 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 SUPERFAMILY SSF46785 1 84 8.08E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 Pfam PF03466 LysR substrate binding domain 87 283 1.8E-27 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 Gene3D G3DSA:3.40.190.10 88 196 7.6E-18 T 09-03-2017 UA74_RS13525 0d7bd74806038573889f94e1e37a8caa 290 SUPERFAMILY SSF53850 89 287 1.63E-25 T 09-03-2017 UA74_RS28955 cced8dcb1ec1b29bc8cc97ee01153bf7 666 Pfam PF13440 Polysaccharide biosynthesis protein 213 457 5.4E-47 T 09-03-2017 UA74_RS16505 135aea34a58b59afb59e7b2eb8098600 177 Pfam PF08659 KR domain 2 177 4.9E-55 T 09-03-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16505 135aea34a58b59afb59e7b2eb8098600 177 Gene3D G3DSA:3.40.50.720 1 176 4.6E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16505 135aea34a58b59afb59e7b2eb8098600 177 SUPERFAMILY SSF51735 1 176 1.18E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16505 135aea34a58b59afb59e7b2eb8098600 177 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 176 1.7E-42 T 09-03-2017 UA74_RS26545 65e47ced7cd938438399e985baca11bd 259 Pfam PF03734 L,D-transpeptidase catalytic domain 142 258 2.2E-10 T 09-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UA74_RS26545 65e47ced7cd938438399e985baca11bd 259 Gene3D G3DSA:2.40.440.10 137 258 3.0E-16 T 09-03-2017 UA74_RS26545 65e47ced7cd938438399e985baca11bd 259 SUPERFAMILY SSF141523 137 258 3.79E-16 T 09-03-2017 UA74_RS07250 d5cd24b4afd8c14f18d8b8b375489fd0 558 Pfam PF00474 Sodium:solute symporter family 44 454 9.8E-48 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS07250 d5cd24b4afd8c14f18d8b8b375489fd0 558 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 159 184 - T 09-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 UA74_RS07250 d5cd24b4afd8c14f18d8b8b375489fd0 558 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 44 457 5.4E-72 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS02955 9a6e5efeabb898f6a41369ee7466af95 143 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 17 126 29.467 T 09-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02955 9a6e5efeabb898f6a41369ee7466af95 143 ProSitePatterns PS00464 Ribosomal protein L22 signature. 99 123 - T 09-03-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02955 9a6e5efeabb898f6a41369ee7466af95 143 Pfam PF00237 Ribosomal protein L22p/L17e 24 123 6.5E-31 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 UA74_RS02955 9a6e5efeabb898f6a41369ee7466af95 143 SUPERFAMILY SSF54843 10 127 9.03E-43 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 UA74_RS02955 9a6e5efeabb898f6a41369ee7466af95 143 Gene3D G3DSA:3.90.470.10 19 127 3.3E-41 T 09-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 UA74_RS02955 9a6e5efeabb898f6a41369ee7466af95 143 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 21 123 1.5E-46 T 09-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS29005 e32818015ce580b5fc224c1b395e417f 283 SUPERFAMILY SSF53448 1 255 1.82E-43 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS29005 e32818015ce580b5fc224c1b395e417f 283 Gene3D G3DSA:3.90.550.10 2 254 1.4E-41 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS22710 903829b6ec0ea9c601939ecb28e2fd83 542 Gene3D G3DSA:3.40.605.10 20 279 1.0E-42 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS22710 903829b6ec0ea9c601939ecb28e2fd83 542 Pfam PF00171 Aldehyde dehydrogenase family 32 445 2.2E-42 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS22710 903829b6ec0ea9c601939ecb28e2fd83 542 SUPERFAMILY SSF53720 36 534 6.41E-92 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS22710 903829b6ec0ea9c601939ecb28e2fd83 542 Gene3D G3DSA:3.40.309.10 281 472 5.1E-46 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 Gene3D G3DSA:3.40.50.720 1 131 1.6E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 SUPERFAMILY SSF116726 144 217 9.55E-12 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 Pfam PF02080 TrkA-C domain 152 215 2.5E-11 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.6E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 1.6E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 1.6E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.6E-7 T 09-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 Gene3D G3DSA:3.30.70.1450 148 220 9.7E-9 T 09-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 SUPERFAMILY SSF51735 1 145 1.23E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08575 ec3370e7345d02f781c6c7e3c5d0fae6 226 Pfam PF02254 TrkA-N domain 3 118 1.3E-24 T 09-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_RS05570 bf5b72398a18b56bef0faab5ac4c3cf9 196 SUPERFAMILY SSF55729 18 180 1.98E-34 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS05570 bf5b72398a18b56bef0faab5ac4c3cf9 196 Pfam PF13302 Acetyltransferase (GNAT) domain 19 156 2.1E-17 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS05570 bf5b72398a18b56bef0faab5ac4c3cf9 196 Gene3D G3DSA:3.40.630.30 18 180 4.6E-35 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS13495 cc3f69ef965ed61b6050391c8537246e 193 Gene3D G3DSA:2.60.120.10 100 180 8.1E-12 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS13495 cc3f69ef965ed61b6050391c8537246e 193 SMART SM00530 15 70 2.0E-18 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS13495 cc3f69ef965ed61b6050391c8537246e 193 Pfam PF01381 Helix-turn-helix 16 70 1.5E-16 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS13495 cc3f69ef965ed61b6050391c8537246e 193 SUPERFAMILY SSF47413 12 75 1.8E-17 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13495 cc3f69ef965ed61b6050391c8537246e 193 SUPERFAMILY SSF51182 66 177 4.98E-20 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS13495 cc3f69ef965ed61b6050391c8537246e 193 Gene3D G3DSA:1.10.260.40 11 81 1.7E-20 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13495 cc3f69ef965ed61b6050391c8537246e 193 Pfam PF07883 Cupin domain 119 177 4.9E-10 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS25150 59dbfdb49cbe821f6af6c8599855acfe 218 Pfam PF11241 Protein of unknown function (DUF3043) 39 207 2.1E-60 T 09-03-2017 IPR021403 Protein of unknown function DUF3043 UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 SUPERFAMILY SSF117892 51 185 2.62E-41 T 09-03-2017 IPR001107 Band 7 domain UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 SMART SM00244 20 178 1.8E-58 T 09-03-2017 IPR001107 Band 7 domain UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 75 96 2.4E-35 T 09-03-2017 IPR001972 Stomatin family GO:0016020 UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 130 153 2.4E-35 T 09-03-2017 IPR001972 Stomatin family GO:0016020 UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 27 49 2.4E-35 T 09-03-2017 IPR001972 Stomatin family GO:0016020 UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 110 127 2.4E-35 T 09-03-2017 IPR001972 Stomatin family GO:0016020 UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 173 194 2.4E-35 T 09-03-2017 IPR001972 Stomatin family GO:0016020 UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 154 172 2.4E-35 T 09-03-2017 IPR001972 Stomatin family GO:0016020 UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 Pfam PF01145 SPFH domain / Band 7 family 24 194 1.4E-34 T 09-03-2017 IPR001107 Band 7 domain UA74_RS11650 a6e6b80fef2f42bc7c87524d179ada63 418 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 09-03-2017 IPR018080 Band 7/stomatin-like, conserved site UA74_RS03845 e5cbf1388c211576804223cb5a8008d5 261 PIRSF PIRSF009160 1 261 1.1E-82 T 09-03-2017 IPR010539 Protein of unknown function UCP009160 UA74_RS03845 e5cbf1388c211576804223cb5a8008d5 261 Pfam PF12811 Bax inhibitor 1 like 35 260 1.1E-85 T 09-03-2017 IPR010539 Protein of unknown function UCP009160 UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 Gene3D G3DSA:1.20.1560.10 6 303 5.9E-26 T 09-03-2017 UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 4 495 2.0E-133 T 09-03-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 SMART SM00382 340 527 2.3E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 SUPERFAMILY SSF52540 309 533 4.74E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 Gene3D G3DSA:3.40.50.300 315 532 1.7E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 SUPERFAMILY SSF90123 5 285 2.22E-30 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 SUPERFAMILY SSF90123 442 450 2.22E-30 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 Pfam PF00664 ABC transporter transmembrane region 10 232 1.9E-7 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS23400 fa64c7047ab8bf52c6ad20ca57425ca7 543 Pfam PF00005 ABC transporter 332 465 1.6E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 SUPERFAMILY SSF52540 10 260 2.66E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 SUPERFAMILY SSF52540 314 559 1.54E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 539 564 0.02 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 282 7.5E-4 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 SMART SM00382 39 238 1.9E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 SMART SM00382 345 537 7.9E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF00005 ABC transporter 337 487 8.0E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF00005 ABC transporter 31 189 2.6E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 Gene3D G3DSA:3.40.50.300 312 561 3.2E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 Gene3D G3DSA:3.40.50.300 9 262 3.5E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20235 5d3945e35c7ccb1123e7414a108a9033 570 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS15335 2eed6139e4feeaecd25247821b062bff 144 Pfam PF08818 Domain of unknown function (DU1801) 52 143 1.9E-6 T 09-03-2017 IPR014922 Domain of unknown function DUF1801 UA74_RS15335 2eed6139e4feeaecd25247821b062bff 144 SUPERFAMILY SSF159888 44 126 7.32E-10 T 09-03-2017 UA74_RS18295 9929b344365e98af54196913ec5cbc3f 345 SUPERFAMILY SSF53822 37 336 7.23E-56 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS18295 9929b344365e98af54196913ec5cbc3f 345 Gene3D G3DSA:3.40.50.2300 155 336 3.0E-32 T 09-03-2017 UA74_RS18295 9929b344365e98af54196913ec5cbc3f 345 Pfam PF13407 Periplasmic binding protein domain 39 299 3.1E-47 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS18295 9929b344365e98af54196913ec5cbc3f 345 Gene3D G3DSA:3.40.50.2300 38 154 1.1E-31 T 09-03-2017 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 PIRSF PIRSF004491 1 317 5.7E-99 T 09-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 Pfam PF06574 FAD synthetase 12 166 1.7E-50 T 09-03-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 SUPERFAMILY SSF82114 174 314 1.09E-40 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 SMART SM00904 183 314 1.5E-53 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 Pfam PF01687 Riboflavin kinase 184 313 1.2E-35 T 09-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 313 2.0E-71 T 09-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 SUPERFAMILY SSF52374 16 175 1.16E-31 T 09-03-2017 UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 Gene3D G3DSA:3.40.50.620 1 179 1.3E-62 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS09430 831dc41d2250de40d919fb3c779c2951 317 Gene3D G3DSA:2.40.30.30 180 314 1.5E-46 T 09-03-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 UA74_RS28520 c6b3b225b3937ff50cc2f0bddefb3227 419 Gene3D G3DSA:1.20.1250.20 247 408 6.2E-6 T 09-03-2017 UA74_RS28520 c6b3b225b3937ff50cc2f0bddefb3227 419 Gene3D G3DSA:1.20.1250.20 47 208 1.2E-5 T 09-03-2017 UA74_RS28520 c6b3b225b3937ff50cc2f0bddefb3227 419 SUPERFAMILY SSF103473 37 410 1.31E-15 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS28520 c6b3b225b3937ff50cc2f0bddefb3227 419 Pfam PF07690 Major Facilitator Superfamily 36 380 1.2E-9 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS02995 25efde8ecf05ba8f4bab85aebfe2421f 61 SUPERFAMILY SSF57716 4 61 5.2E-22 T 09-03-2017 UA74_RS02995 25efde8ecf05ba8f4bab85aebfe2421f 61 Gene3D G3DSA:4.10.830.10 1 61 7.8E-28 T 09-03-2017 UA74_RS02995 25efde8ecf05ba8f4bab85aebfe2421f 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.208 T 09-03-2017 IPR023053 Ribosomal protein S14, type Z UA74_RS02995 25efde8ecf05ba8f4bab85aebfe2421f 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 09-03-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS02995 25efde8ecf05ba8f4bab85aebfe2421f 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.4E-24 T 09-03-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS15355 cc14553a689a0f64781fe05c7d752cd8 213 Gene3D G3DSA:1.10.357.10 9 205 8.2E-30 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15355 cc14553a689a0f64781fe05c7d752cd8 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.6E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15355 cc14553a689a0f64781fe05c7d752cd8 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.6E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15355 cc14553a689a0f64781fe05c7d752cd8 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.2E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15355 cc14553a689a0f64781fe05c7d752cd8 213 SUPERFAMILY SSF46689 4 72 7.09E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20145 1dece367f47650b48da212dea10e15d7 317 Gene3D G3DSA:1.10.3720.10 28 303 5.8E-58 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20145 1dece367f47650b48da212dea10e15d7 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 303 4.7E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS20145 1dece367f47650b48da212dea10e15d7 317 SUPERFAMILY SSF161098 75 302 7.06E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 43 251 6.4E-44 T 09-03-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 SUPERFAMILY SSF49503 122 258 1.75E-32 T 09-03-2017 IPR008972 Cupredoxin UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 SUPERFAMILY SSF81464 17 115 8.99E-22 T 09-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 164 241 2.3E-14 T 09-03-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 224 241 8.1E-8 T 09-03-2017 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 123 142 8.1E-8 T 09-03-2017 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 206 223 8.1E-8 T 09-03-2017 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 88 100 8.1E-8 T 09-03-2017 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 182 235 - T 09-03-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 Gene3D G3DSA:2.60.40.420 116 267 1.6E-34 T 09-03-2017 IPR008972 Cupredoxin UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 Gene3D G3DSA:1.10.287.90 32 115 1.6E-18 T 09-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS25080 da59bd7e790b39e452b3693c0d117698 305 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 34 107 8.7E-5 T 09-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS13975 d0c2b132a0ab0f14c8e11dc3af87576d 340 Gene3D G3DSA:3.40.190.10 129 248 7.0E-15 T 09-03-2017 UA74_RS13975 d0c2b132a0ab0f14c8e11dc3af87576d 340 Pfam PF09084 NMT1/THI5 like 50 255 1.0E-42 T 09-03-2017 IPR015168 SsuA/THI5-like UA74_RS13975 d0c2b132a0ab0f14c8e11dc3af87576d 340 SUPERFAMILY SSF53850 38 262 1.72E-34 T 09-03-2017 UA74_RS01090 9c4d030a73aacd1ae2dc747c597db225 79 Gene3D G3DSA:2.10.230.10 30 71 4.1E-4 T 09-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_RS04380 0a0779ef882bda3235a0f505b4e14cb6 244 Gene3D G3DSA:1.10.10.10 126 224 1.7E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04380 0a0779ef882bda3235a0f505b4e14cb6 244 Gene3D G3DSA:3.40.50.2300 2 125 2.4E-35 T 09-03-2017 UA74_RS04380 0a0779ef882bda3235a0f505b4e14cb6 244 SUPERFAMILY SSF52172 3 182 1.18E-38 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS04380 0a0779ef882bda3235a0f505b4e14cb6 244 Pfam PF00072 Response regulator receiver domain 5 113 6.3E-25 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS04380 0a0779ef882bda3235a0f505b4e14cb6 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 1.8E-23 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS04380 0a0779ef882bda3235a0f505b4e14cb6 244 SMART SM00448 3 114 2.5E-38 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS04380 0a0779ef882bda3235a0f505b4e14cb6 244 SMART SM00862 148 223 1.1E-21 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS22515 e8651ed907859fede8c5dd8fc8879010 247 SUPERFAMILY SSF53335 8 232 5.72E-33 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS22515 e8651ed907859fede8c5dd8fc8879010 247 Gene3D G3DSA:3.40.50.150 198 227 7.3E-33 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS22515 e8651ed907859fede8c5dd8fc8879010 247 Gene3D G3DSA:3.40.50.150 14 157 7.3E-33 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS22515 e8651ed907859fede8c5dd8fc8879010 247 Pfam PF13649 Methyltransferase domain 40 132 3.7E-16 T 09-03-2017 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 SUPERFAMILY SSF51735 125 278 2.39E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 8.2E-24 T 09-03-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 3.4E-50 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 3.4E-50 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 254 272 3.4E-50 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 3.4E-50 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.4E-50 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 3.4E-50 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 278 29.906 T 09-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 Gene3D G3DSA:3.40.192.10 7 138 1.8E-29 T 09-03-2017 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 SUPERFAMILY SSF53223 1 121 1.15E-25 T 09-03-2017 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 277 2.0E-54 T 09-03-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 UA74_RS15075 59134bd5541f395aa33c3ac3e4ac440a 279 Gene3D G3DSA:3.40.50.720 139 262 3.1E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29555 7775ddd6d79bac868e18f2efe723ef7b 143 Gene3D G3DSA:1.10.10.10 13 142 2.9E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS29555 7775ddd6d79bac868e18f2efe723ef7b 143 SUPERFAMILY SSF46785 13 142 1.06E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10770 c4a1e12e051a27b9d010c6526224aa84 143 Gene3D G3DSA:3.10.180.10 7 142 3.8E-8 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS10770 c4a1e12e051a27b9d010c6526224aa84 143 SUPERFAMILY SSF54593 88 142 2.56E-7 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS10770 c4a1e12e051a27b9d010c6526224aa84 143 SUPERFAMILY SSF54593 3 35 2.56E-7 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 SMART SM00642 199 534 2.2E-5 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 Gene3D G3DSA:3.20.20.80 172 558 7.9E-69 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 Gene3D G3DSA:3.20.20.80 67 124 7.9E-69 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 659 44.804 T 09-03-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 SUPERFAMILY SSF51445 199 559 1.69E-81 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 Pfam PF00128 Alpha amylase, catalytic domain 221 326 5.0E-5 T 09-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 Gene3D G3DSA:2.60.40.1180 564 647 2.5E-5 T 09-03-2017 IPR013780 Glycosyl hydrolase, all-beta UA74_RS07625 3559859ff54b9837b22bcfc9221db884 660 Pfam PF11896 Domain of unknown function (DUF3416) 3 193 5.4E-58 T 09-03-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 UA74_RS21515 c4ca71ac2dcd6813d98ce36259975201 281 Pfam PF02616 Segregation and condensation protein ScpA 36 256 6.1E-61 T 09-03-2017 IPR003768 Segregation and condensation protein A UA74_RS21410 3cb5166ec987a44bc2049c17380653ec 327 SUPERFAMILY SSF53807 64 320 8.24E-52 T 09-03-2017 UA74_RS21410 3cb5166ec987a44bc2049c17380653ec 327 Gene3D G3DSA:3.40.50.1980 73 189 2.3E-22 T 09-03-2017 UA74_RS21410 3cb5166ec987a44bc2049c17380653ec 327 Gene3D G3DSA:3.40.50.1980 191 319 1.3E-22 T 09-03-2017 UA74_RS21410 3cb5166ec987a44bc2049c17380653ec 327 Pfam PF01497 Periplasmic binding protein 76 300 1.5E-25 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS02775 1e7947e0d2c380a7930338cfd514f8e6 163 SUPERFAMILY SSF89963 5 87 3.66E-26 T 09-03-2017 IPR007551 Protein of unknown function DUF520 UA74_RS02775 1e7947e0d2c380a7930338cfd514f8e6 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 24.943 T 09-03-2017 IPR007551 Protein of unknown function DUF520 UA74_RS02775 1e7947e0d2c380a7930338cfd514f8e6 163 Gene3D G3DSA:3.30.70.860 98 163 1.9E-29 T 09-03-2017 UA74_RS02775 1e7947e0d2c380a7930338cfd514f8e6 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 2.8E-60 T 09-03-2017 IPR007551 Protein of unknown function DUF520 UA74_RS02775 1e7947e0d2c380a7930338cfd514f8e6 163 SUPERFAMILY SSF89963 92 163 1.18E-23 T 09-03-2017 IPR007551 Protein of unknown function DUF520 UA74_RS02775 1e7947e0d2c380a7930338cfd514f8e6 163 Gene3D G3DSA:3.30.70.990 11 97 1.1E-28 T 09-03-2017 UA74_RS11925 6dd4d816af29879360ef919a95852bc1 576 SUPERFAMILY SSF69318 499 530 6.02E-16 T 09-03-2017 UA74_RS11925 6dd4d816af29879360ef919a95852bc1 576 SUPERFAMILY SSF69318 100 364 6.02E-16 T 09-03-2017 UA74_RS11925 6dd4d816af29879360ef919a95852bc1 576 Gene3D G3DSA:2.130.10.130 17 185 4.1E-5 T 09-03-2017 UA74_RS11925 6dd4d816af29879360ef919a95852bc1 576 Gene3D G3DSA:2.130.10.130 237 349 4.1E-5 T 09-03-2017 UA74_RS23240 e6f8b7dca0f9a9524250d074c369a151 227 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 7 200 2.3E-25 T 09-03-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 UA74_RS23240 e6f8b7dca0f9a9524250d074c369a151 227 Gene3D G3DSA:1.10.3630.10 17 209 2.0E-11 T 09-03-2017 UA74_RS24655 a3ac8adabec5f37c7e4ebe5e337a3227 365 Gene3D G3DSA:3.40.190.10 134 263 1.9E-13 T 09-03-2017 UA74_RS24655 a3ac8adabec5f37c7e4ebe5e337a3227 365 SUPERFAMILY SSF53850 49 278 9.96E-35 T 09-03-2017 UA74_RS24655 a3ac8adabec5f37c7e4ebe5e337a3227 365 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 50 343 1.2E-53 T 09-03-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 UA74_RS24655 a3ac8adabec5f37c7e4ebe5e337a3227 365 Pfam PF13379 NMT1-like family 47 281 2.0E-27 T 09-03-2017 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 SUPERFAMILY SSF81891 183 496 3.79E-60 T 09-03-2017 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 SMART SM00471 282 502 4.2E-4 T 09-03-2017 IPR003607 HD/PDEase domain UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 SUPERFAMILY SSF81301 29 178 3.81E-32 T 09-03-2017 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 22 496 1.4E-231 T 09-03-2017 IPR014065 tRNA adenylyltransferase UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 212 271 4.1E-15 T 09-03-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 Gene3D G3DSA:1.10.3090.10 443 465 3.2E-52 T 09-03-2017 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 Gene3D G3DSA:1.10.3090.10 183 375 3.2E-52 T 09-03-2017 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 TIGRFAM TIGR00277 HDIG: HDIG domain 283 368 3.9E-17 T 09-03-2017 IPR006675 HDIG domain UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 Gene3D G3DSA:3.30.460.10 29 178 8.1E-38 T 09-03-2017 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 Pfam PF01743 Poly A polymerase head domain 46 179 1.3E-28 T 09-03-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 UA74_RS30365 702b2b2f97f7d6f861d71890d4f2a46a 508 Pfam PF01966 HD domain 286 411 1.6E-13 T 09-03-2017 IPR006674 HD domain UA74_RS15305 2a2a7516a291c30e18fbdf829e60087c 199 Pfam PF13977 Bacterial transcriptional repressor 85 196 1.2E-9 T 09-03-2017 UA74_RS15305 2a2a7516a291c30e18fbdf829e60087c 199 Gene3D G3DSA:1.10.357.10 1 198 5.0E-36 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15305 2a2a7516a291c30e18fbdf829e60087c 199 SUPERFAMILY SSF48498 83 197 2.08E-14 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS15305 2a2a7516a291c30e18fbdf829e60087c 199 SUPERFAMILY SSF46689 1 68 7.18E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15305 2a2a7516a291c30e18fbdf829e60087c 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 3.2E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26975 46ef6fff87a8766d10f05419e4f08190 396 Pfam PF01139 tRNA-splicing ligase RtcB 28 396 6.9E-124 T 09-03-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 UA74_RS26975 46ef6fff87a8766d10f05419e4f08190 396 SUPERFAMILY SSF103365 9 396 5.23E-125 T 09-03-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 UA74_RS10560 6e1fc379cedda365f2c4c98b9e8fae60 327 SUPERFAMILY SSF51430 1 316 1.57E-71 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS10560 6e1fc379cedda365f2c4c98b9e8fae60 327 Gene3D G3DSA:3.20.20.100 1 307 5.4E-70 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS10560 6e1fc379cedda365f2c4c98b9e8fae60 327 Pfam PF00248 Aldo/keto reductase family 16 309 1.2E-56 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS22165 40d719fd3446df39c697b06318e4b9be 551 Gene3D G3DSA:2.130.10.10 202 437 9.5E-4 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS22165 40d719fd3446df39c697b06318e4b9be 551 Gene3D G3DSA:2.130.10.10 490 539 9.5E-4 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS22165 40d719fd3446df39c697b06318e4b9be 551 SUPERFAMILY SSF54001 59 149 1.67E-6 T 09-03-2017 UA74_RS22165 40d719fd3446df39c697b06318e4b9be 551 Gene3D G3DSA:3.90.1720.10 62 149 1.5E-9 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain UA74_RS22165 40d719fd3446df39c697b06318e4b9be 551 SUPERFAMILY SSF89372 205 431 8.5E-14 T 09-03-2017 UA74_RS15345 a3acf8d571d6685ff013a5fef2aae56d 266 Gene3D G3DSA:3.10.180.10 3 126 4.7E-17 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15345 a3acf8d571d6685ff013a5fef2aae56d 266 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 145 261 1.0E-5 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS15345 a3acf8d571d6685ff013a5fef2aae56d 266 SUPERFAMILY SSF54593 145 265 7.56E-17 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15345 a3acf8d571d6685ff013a5fef2aae56d 266 Gene3D G3DSA:3.10.180.10 144 264 5.1E-22 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS15345 a3acf8d571d6685ff013a5fef2aae56d 266 SUPERFAMILY SSF54593 1 124 1.09E-11 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 SUPERFAMILY SSF118215 18 416 1.96E-96 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 Gene3D G3DSA:1.10.3860.10 10 419 1.7E-104 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 Pfam PF00375 Sodium:dicarboxylate symporter family 18 415 2.1E-106 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 370 390 6.5E-29 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 58 78 6.5E-29 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 92 117 6.5E-29 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 16 36 6.5E-29 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 309 335 6.5E-29 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 344 363 6.5E-29 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS27140 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 6.5E-29 T 09-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_RS24730 9b40bc5d910ca532a7c369d4df0e0227 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 5.1E-30 T 09-03-2017 IPR021408 Protein of unknown function DUF3046 UA74_RS29510 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 SUPERFAMILY SSF53383 7 336 3.35E-90 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS29510 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 PIRSF PIRSF017617 1 337 2.4E-105 T 09-03-2017 IPR023603 Threonine aldolase UA74_RS29510 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 Gene3D G3DSA:3.90.1150.10 255 336 6.4E-18 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS29510 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 Pfam PF01212 Beta-eliminating lyase 8 292 1.3E-71 T 09-03-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 UA74_RS29510 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 Gene3D G3DSA:3.40.640.10 4 253 5.2E-66 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS24350 cfe6b9b61f347ee366628e77c474cfec 374 Gene3D G3DSA:3.40.710.10 10 366 1.6E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS24350 cfe6b9b61f347ee366628e77c474cfec 374 Pfam PF00144 Beta-lactamase 20 357 7.7E-50 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS24350 cfe6b9b61f347ee366628e77c474cfec 374 SUPERFAMILY SSF56601 15 360 1.66E-59 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS13820 9a9800056b70040002655e86973b8540 191 SUPERFAMILY SSF160904 2 170 1.44E-34 T 09-03-2017 UA74_RS13820 9a9800056b70040002655e86973b8540 191 Gene3D G3DSA:1.10.3300.10 8 172 3.9E-36 T 09-03-2017 IPR023286 ABATE domain UA74_RS13820 9a9800056b70040002655e86973b8540 191 Pfam PF11706 CGNR zinc finger 129 171 1.5E-14 T 09-03-2017 IPR021005 Zinc finger, CGNR UA74_RS23360 b25ebe8ad1088705f2ade3330ceaadd6 224 Gene3D G3DSA:3.30.70.900 129 198 1.3E-8 T 09-03-2017 UA74_RS23360 b25ebe8ad1088705f2ade3330ceaadd6 224 Gene3D G3DSA:3.30.70.900 21 114 3.7E-10 T 09-03-2017 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 SUPERFAMILY SSF51569 4 340 2.56E-98 T 09-03-2017 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 PIRSF PIRSF001359 6 341 6.1E-66 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 6.9E-81 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 339 1.5E-142 T 09-03-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 Gene3D G3DSA:3.20.20.70 2 341 1.3E-120 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS29640 941d837cc336c9fe5c9c1d147be424c8 344 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 5.9E-76 T 09-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 SUPERFAMILY SSF52425 5 172 1.31E-42 T 09-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Pfam PF00875 DNA photolyase 7 158 1.6E-40 T 09-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 375 389 6.4E-23 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 316 332 6.4E-23 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 138 154 6.4E-23 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 336 354 6.4E-23 T 09-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 SUPERFAMILY SSF48173 189 459 2.49E-98 T 09-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Gene3D G3DSA:1.25.40.80 197 272 4.5E-33 T 09-03-2017 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Gene3D G3DSA:1.10.579.10 273 460 1.2E-74 T 09-03-2017 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Pfam PF03441 FAD binding domain of DNA photolyase 264 457 1.2E-78 T 09-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 UA74_RS28395 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Gene3D G3DSA:3.40.50.620 5 159 8.5E-40 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS26430 80f5ed81a9b42838e60d4544344cfd6c 292 SUPERFAMILY SSF53474 5 292 4.8E-63 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26430 80f5ed81a9b42838e60d4544344cfd6c 292 Pfam PF00561 alpha/beta hydrolase fold 31 138 9.2E-21 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS26430 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 36 54 2.1E-8 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS26430 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 267 289 2.1E-8 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS26430 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 117 130 2.1E-8 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS26430 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 103 116 2.1E-8 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS26430 80f5ed81a9b42838e60d4544344cfd6c 292 Gene3D G3DSA:3.40.50.1820 2 292 1.1E-61 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24270 14348b298ed1c00e94e6b5293e2059a7 383 SUPERFAMILY SSF48230 156 325 1.19E-7 T 09-03-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 UA74_RS07725 897cb26bb023d15a94f5db85d1247bcd 503 SUPERFAMILY SSF53474 5 477 1.12E-107 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07725 897cb26bb023d15a94f5db85d1247bcd 503 Pfam PF00135 Carboxylesterase family 4 483 1.4E-98 T 09-03-2017 IPR002018 Carboxylesterase, type B UA74_RS07725 897cb26bb023d15a94f5db85d1247bcd 503 Gene3D G3DSA:3.40.50.1820 5 502 1.6E-131 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12480 8eee32e6464a1e085c0a058fb57cd3a2 277 Gene3D G3DSA:3.50.50.60 113 203 4.5E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12480 8eee32e6464a1e085c0a058fb57cd3a2 277 Gene3D G3DSA:3.50.50.60 7 71 4.5E-23 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12480 8eee32e6464a1e085c0a058fb57cd3a2 277 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.2E-11 T 09-03-2017 UA74_RS12480 8eee32e6464a1e085c0a058fb57cd3a2 277 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 1.2E-11 T 09-03-2017 UA74_RS12480 8eee32e6464a1e085c0a058fb57cd3a2 277 Pfam PF01494 FAD binding domain 6 275 1.3E-43 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS12480 8eee32e6464a1e085c0a058fb57cd3a2 277 SUPERFAMILY SSF51905 7 190 5.51E-24 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS30170 8d9921eb67dcb1c78b4e2b518ad1359e 168 Gene3D G3DSA:2.40.50.140 3 117 9.1E-41 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS30170 8d9921eb67dcb1c78b4e2b518ad1359e 168 SUPERFAMILY SSF50249 6 168 1.86E-46 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS30170 8d9921eb67dcb1c78b4e2b518ad1359e 168 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 131 1.4E-32 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UA74_RS30170 8d9921eb67dcb1c78b4e2b518ad1359e 168 Pfam PF00436 Single-strand binding protein family 6 106 1.1E-28 T 09-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 UA74_RS30170 8d9921eb67dcb1c78b4e2b518ad1359e 168 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 31.305 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UA74_RS15875 c6484bd92bccd5bd1e3a5fd8be165c0f 193 Gene3D G3DSA:1.10.150.240 13 75 7.6E-16 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 UA74_RS15875 c6484bd92bccd5bd1e3a5fd8be165c0f 193 Gene3D G3DSA:3.40.50.1000 77 188 8.4E-17 T 09-03-2017 IPR023214 HAD-like domain UA74_RS15875 c6484bd92bccd5bd1e3a5fd8be165c0f 193 SUPERFAMILY SSF56784 1 184 3.0E-24 T 09-03-2017 IPR023214 HAD-like domain UA74_RS11700 e8b74ad3ec3a8a767ef8ad3a1b529110 252 PIRSF PIRSF015736 14 248 1.7E-62 T 09-03-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 Pfam PF04545 Sigma-70, region 4 202 251 1.1E-14 T 09-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 250 2.4E-32 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 Gene3D G3DSA:1.10.10.10 194 254 3.8E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 Gene3D G3DSA:1.10.10.10 110 163 3.0E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 Pfam PF04539 Sigma-70 region 3 125 163 4.2E-9 T 09-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 Pfam PF04542 Sigma-70 region 2 41 110 2.3E-16 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 SUPERFAMILY SSF88946 14 110 4.45E-28 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 PRINTS PR00046 Major sigma-70 factor signature 223 238 1.5E-6 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 PRINTS PR00046 Major sigma-70 factor signature 206 218 1.5E-6 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 PRINTS PR00046 Major sigma-70 factor signature 65 78 1.5E-6 T 09-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 SUPERFAMILY SSF88659 175 253 4.86E-15 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 35 251 5.1E-79 T 09-03-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 SUPERFAMILY SSF88659 114 184 3.36E-14 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS23530 2ad3176642a752dccdfa0b91f8c1e670 261 Gene3D G3DSA:1.10.601.10 21 109 1.6E-20 T 09-03-2017 UA74_RS11080 930ee880c9a3db9c073157fbeb1ec0df 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 277 365 1.0E-18 T 09-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_RS11080 930ee880c9a3db9c073157fbeb1ec0df 413 SUPERFAMILY SSF53901 217 408 1.1E-45 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11080 930ee880c9a3db9c073157fbeb1ec0df 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 246 5.3E-31 T 09-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_RS11080 930ee880c9a3db9c073157fbeb1ec0df 413 SMART SM00825 Beta-ketoacyl synthase 10 412 5.2E-4 T 09-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_RS11080 930ee880c9a3db9c073157fbeb1ec0df 413 Gene3D G3DSA:3.40.47.10 10 256 2.9E-48 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11080 930ee880c9a3db9c073157fbeb1ec0df 413 SUPERFAMILY SSF53901 11 254 3.67E-57 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS11080 930ee880c9a3db9c073157fbeb1ec0df 413 Gene3D G3DSA:3.40.47.10 278 409 1.1E-36 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS21860 4173b5b21f6aca28982088727da3553b 394 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 11 385 2.4E-129 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS21860 4173b5b21f6aca28982088727da3553b 394 PIRSF PIRSF006078 10 389 2.2E-105 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS21860 4173b5b21f6aca28982088727da3553b 394 Gene3D G3DSA:3.90.1510.10 52 286 1.0E-78 T 09-03-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 UA74_RS21860 4173b5b21f6aca28982088727da3553b 394 SUPERFAMILY SSF110738 11 386 3.53E-112 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS21860 4173b5b21f6aca28982088727da3553b 394 Pfam PF02595 Glycerate kinase family 12 384 4.5E-128 T 09-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_RS08990 5368f7079fe35ee37706f6eae0f669ec 343 SUPERFAMILY SSF52540 4 251 2.47E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08990 5368f7079fe35ee37706f6eae0f669ec 343 Gene3D G3DSA:3.40.50.300 2 253 1.7E-75 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08990 5368f7079fe35ee37706f6eae0f669ec 343 Pfam PF00005 ABC transporter 28 180 2.6E-35 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS08990 5368f7079fe35ee37706f6eae0f669ec 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 336 1.4E-13 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS08990 5368f7079fe35ee37706f6eae0f669ec 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 317 9.6E-14 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS08990 5368f7079fe35ee37706f6eae0f669ec 343 SMART SM00382 36 230 1.4E-20 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08990 5368f7079fe35ee37706f6eae0f669ec 343 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS20150 e49b803424e2b9ca5ef1b3913b0451d5 418 Gene3D G3DSA:3.40.190.10 127 345 6.4E-27 T 09-03-2017 UA74_RS20150 e49b803424e2b9ca5ef1b3913b0451d5 418 Pfam PF01547 Bacterial extracellular solute-binding protein 26 313 1.6E-25 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS20150 e49b803424e2b9ca5ef1b3913b0451d5 418 SUPERFAMILY SSF53850 21 414 2.64E-58 T 09-03-2017 UA74_RS20150 e49b803424e2b9ca5ef1b3913b0451d5 418 Gene3D G3DSA:3.40.190.10 23 126 2.6E-23 T 09-03-2017 UA74_RS09645 e811b21074fa09f93d4c29fd96f6be70 263 SUPERFAMILY SSF53335 23 203 1.27E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09645 e811b21074fa09f93d4c29fd96f6be70 263 Gene3D G3DSA:3.40.50.150 26 202 1.1E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09645 e811b21074fa09f93d4c29fd96f6be70 263 Pfam PF13489 Methyltransferase domain 13 196 4.8E-18 T 09-03-2017 UA74_RS27665 5aeee8a3a921c7058690312238687806 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 327 2.7E-36 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS10545 92222d826c42b9b8dfef46690f7afe61 503 Pfam PF01740 STAS domain 414 491 9.4E-8 T 09-03-2017 IPR002645 STAS domain UA74_RS10545 92222d826c42b9b8dfef46690f7afe61 503 Gene3D G3DSA:3.30.750.24 412 491 8.0E-9 T 09-03-2017 IPR002645 STAS domain UA74_RS10545 92222d826c42b9b8dfef46690f7afe61 503 Pfam PF00916 Sulfate permease family 178 369 8.8E-27 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UA74_RS10545 92222d826c42b9b8dfef46690f7afe61 503 Pfam PF00916 Sulfate permease family 31 154 2.6E-20 T 09-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UA74_RS10545 92222d826c42b9b8dfef46690f7afe61 503 SUPERFAMILY SSF52091 410 491 3.73E-13 T 09-03-2017 IPR002645 STAS domain UA74_RS21195 9842bf54f88b0b82ae30664cee03adef 51 Pfam PF01783 Ribosomal L32p protein family 2 30 8.5E-11 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21195 9842bf54f88b0b82ae30664cee03adef 51 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 51 12.837 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21195 9842bf54f88b0b82ae30664cee03adef 51 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 33 2.2E-11 T 09-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21195 9842bf54f88b0b82ae30664cee03adef 51 SUPERFAMILY SSF57829 1 37 5.19E-9 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_RS30065 e6951405a8867ef9db7fb076fe894e66 274 Gene3D G3DSA:1.10.3720.10 52 255 1.2E-43 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS30065 e6951405a8867ef9db7fb076fe894e66 274 SUPERFAMILY SSF161098 51 241 7.33E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS30065 e6951405a8867ef9db7fb076fe894e66 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 255 9.6E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS30065 e6951405a8867ef9db7fb076fe894e66 274 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 52 147 2.5E-17 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 UA74_RS13835 9dbef47ba92fa4045321322f12c97170 301 Gene3D G3DSA:1.10.10.10 160 300 3.8E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13835 9dbef47ba92fa4045321322f12c97170 301 SUPERFAMILY SSF46785 169 300 9.52E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01355 327a97ee508ce9aec397bd6eefefb998 360 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 122 282 5.1E-10 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain UA74_RS01355 327a97ee508ce9aec397bd6eefefb998 360 Gene3D G3DSA:3.40.50.300 118 333 1.4E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01355 327a97ee508ce9aec397bd6eefefb998 360 SUPERFAMILY SSF52172 2 114 3.98E-6 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS01355 327a97ee508ce9aec397bd6eefefb998 360 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 11 350 6.4E-101 T 09-03-2017 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like UA74_RS01355 327a97ee508ce9aec397bd6eefefb998 360 SUPERFAMILY SSF52540 119 334 1.67E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS06355 eb777ab31a84b8ead70f17810363eefd 161 Gene3D G3DSA:3.40.30.10 4 155 1.4E-47 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS06355 eb777ab31a84b8ead70f17810363eefd 161 Pfam PF00578 AhpC/TSA family 10 137 9.3E-36 T 09-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS06355 eb777ab31a84b8ead70f17810363eefd 161 PIRSF PIRSF000239 2 155 5.6E-19 T 09-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_RS06355 eb777ab31a84b8ead70f17810363eefd 161 SUPERFAMILY SSF52833 6 155 1.98E-46 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 SUPERFAMILY SSF46785 24 154 1.12E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 7.9E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 7.9E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 7.9E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 7.9E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 SMART SM00347 40 140 4.5E-19 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 Gene3D G3DSA:1.10.10.10 23 154 2.4E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13570 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 Pfam PF01047 MarR family 54 104 2.3E-13 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 SUPERFAMILY SSF56801 24 479 2.09E-79 T 09-03-2017 UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:3.40.50.980 159 313 1.7E-24 T 09-03-2017 UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:3.30.300.30 374 468 5.5E-13 T 09-03-2017 UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 Pfam PF00501 AMP-binding enzyme 41 375 7.3E-42 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 Pfam PF13193 AMP-binding enzyme C-terminal domain 385 467 1.0E-8 T 09-03-2017 IPR025110 AMP-binding enzyme C-terminal domain UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 09-03-2017 IPR020845 AMP-binding, conserved site UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:1.10.10.10 483 541 3.2E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:3.40.50.980 43 158 1.6E-13 T 09-03-2017 UA74_RS17010 7a266523c2a428bd6a80ba8b2d99acce 782 SUPERFAMILY SSF53335 615 755 3.77E-5 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 Pfam PF07687 Peptidase dimerisation domain 206 342 1.3E-14 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 88 97 - T 09-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 Gene3D G3DSA:3.30.70.360 219 259 7.9E-23 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 Gene3D G3DSA:3.30.70.360 296 341 7.9E-23 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 SUPERFAMILY SSF55031 209 248 1.26E-9 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 SUPERFAMILY SSF55031 295 349 1.26E-9 T 09-03-2017 IPR011650 Peptidase M20, dimerisation domain UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 Pfam PF01546 Peptidase family M20/M25/M40 89 443 2.3E-37 T 09-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 SUPERFAMILY SSF53187 11 209 1.14E-53 T 09-03-2017 UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 SUPERFAMILY SSF53187 355 443 1.14E-53 T 09-03-2017 UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 Gene3D G3DSA:3.40.630.10 15 218 6.6E-58 T 09-03-2017 UA74_RS15720 71b614a725189763c52b6a7487355a7b 445 Gene3D G3DSA:3.40.630.10 380 443 6.6E-58 T 09-03-2017 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 170 386 2.9E-71 T 09-03-2017 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 SUPERFAMILY SSF55021 8 77 8.59E-9 T 09-03-2017 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 Gene3D G3DSA:3.30.70.260 113 184 3.1E-5 T 09-03-2017 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 Gene3D G3DSA:3.30.70.260 8 80 2.1E-12 T 09-03-2017 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 Gene3D G3DSA:1.10.150.210 194 244 6.3E-22 T 09-03-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 Gene3D G3DSA:3.40.50.1000 245 374 3.6E-45 T 09-03-2017 IPR023214 HAD-like domain UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 184 354 8.7E-28 T 09-03-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 SUPERFAMILY SSF56784 182 391 2.94E-49 T 09-03-2017 IPR023214 HAD-like domain UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 Pfam PF12710 haloacid dehalogenase-like hydrolase 185 352 9.2E-25 T 09-03-2017 UA74_RS06245 c94a05ca925ec9913cdf9d2c1c1f7ff7 411 Pfam PF13740 ACT domain 9 80 1.7E-16 T 09-03-2017 UA74_RS23115 c80d6bde1f0c3f72cd896c4828fe50c5 282 Pfam PF13560 Helix-turn-helix domain 14 65 4.5E-11 T 09-03-2017 UA74_RS23115 c80d6bde1f0c3f72cd896c4828fe50c5 282 SMART SM00530 17 72 1.1E-8 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS23115 c80d6bde1f0c3f72cd896c4828fe50c5 282 Gene3D G3DSA:1.10.260.40 7 71 3.5E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23115 c80d6bde1f0c3f72cd896c4828fe50c5 282 SUPERFAMILY SSF47413 11 72 1.18E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS00950 9906148015ddfa659f55e71ff3fe3037 386 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 123 2.5E-7 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS00950 9906148015ddfa659f55e71ff3fe3037 386 Pfam PF13378 Enolase C-terminal domain-like 154 373 1.8E-37 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS00950 9906148015ddfa659f55e71ff3fe3037 386 SUPERFAMILY SSF54826 21 123 3.18E-16 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS00950 9906148015ddfa659f55e71ff3fe3037 386 Gene3D G3DSA:3.20.20.120 129 367 1.3E-45 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS00950 9906148015ddfa659f55e71ff3fe3037 386 SMART SM00922 147 248 2.7E-13 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS00950 9906148015ddfa659f55e71ff3fe3037 386 Gene3D G3DSA:3.30.390.10 1 128 3.2E-23 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS00950 9906148015ddfa659f55e71ff3fe3037 386 SUPERFAMILY SSF51604 123 382 2.36E-46 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS13715 138562a721a6df716a6f6ee145088aa8 365 Gene3D G3DSA:1.20.120.420 14 178 7.9E-22 T 09-03-2017 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 UA74_RS13715 138562a721a6df716a6f6ee145088aa8 365 Pfam PF01008 Initiation factor 2 subunit family 71 350 2.1E-46 T 09-03-2017 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 UA74_RS13715 138562a721a6df716a6f6ee145088aa8 365 SUPERFAMILY SSF100950 14 358 1.26E-74 T 09-03-2017 UA74_RS13715 138562a721a6df716a6f6ee145088aa8 365 Gene3D G3DSA:3.40.50.10470 179 358 2.4E-42 T 09-03-2017 UA74_RS00175 0692b2ed9f3757a26c6f8a93370b5496 216 Gene3D G3DSA:3.40.50.720 3 207 4.1E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00175 0692b2ed9f3757a26c6f8a93370b5496 216 SUPERFAMILY SSF51735 2 204 1.07E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS00175 0692b2ed9f3757a26c6f8a93370b5496 216 Pfam PF13460 NAD(P)H-binding 7 193 1.2E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11290 22ac92a2c2c9aecd52373901ee6f8b60 287 Gene3D G3DSA:1.10.260.40 7 70 3.9E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS11290 22ac92a2c2c9aecd52373901ee6f8b60 287 Pfam PF13560 Helix-turn-helix domain 12 73 1.1E-11 T 09-03-2017 UA74_RS11290 22ac92a2c2c9aecd52373901ee6f8b60 287 SUPERFAMILY SSF47413 9 72 1.69E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS11290 22ac92a2c2c9aecd52373901ee6f8b60 287 SMART SM00530 16 71 6.7E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 Pfam PF12796 Ankyrin repeats (3 copies) 17 107 2.4E-14 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 SUPERFAMILY SSF48403 17 145 3.37E-24 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 Gene3D G3DSA:1.25.40.20 95 145 2.4E-14 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 SMART SM00248 120 150 0.033 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 SMART SM00248 42 71 0.11 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 SMART SM00248 78 107 1.0E-4 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 PRINTS PR01415 Ankyrin repeat signature 94 108 1.4E-7 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 PRINTS PR01415 Ankyrin repeat signature 43 58 1.4E-7 T 09-03-2017 IPR002110 Ankyrin repeat GO:0005515 UA74_RS18580 05e8de94239506c56d8cc1f58e9cafab 155 Gene3D G3DSA:1.25.40.20 15 94 1.1E-18 T 09-03-2017 IPR020683 Ankyrin repeat-containing domain UA74_RS28320 7314c84a3024f6ecb20f2a07253eaf9f 212 SUPERFAMILY SSF53335 33 211 1.21E-43 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28320 7314c84a3024f6ecb20f2a07253eaf9f 212 Gene3D G3DSA:3.40.50.150 17 210 1.5E-62 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28320 7314c84a3024f6ecb20f2a07253eaf9f 212 Pfam PF01596 O-methyltransferase 18 207 7.7E-37 T 09-03-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 UA74_RS17140 deefaf9775217ce6a671d21277b71e4a 156 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.8E-39 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS17140 deefaf9775217ce6a671d21277b71e4a 156 Gene3D G3DSA:3.40.1400.10 1 148 7.7E-53 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS17140 deefaf9775217ce6a671d21277b71e4a 156 PIRSF PIRSF005384 1 148 7.1E-47 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS17140 deefaf9775217ce6a671d21277b71e4a 156 Pfam PF02502 Ribose/Galactose Isomerase 3 141 8.9E-45 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS17140 deefaf9775217ce6a671d21277b71e4a 156 SUPERFAMILY SSF89623 1 144 8.76E-48 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS27235 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 Gene3D G3DSA:3.20.20.150 2 318 1.6E-74 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27235 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 SUPERFAMILY SSF51658 8 318 2.75E-57 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27235 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 2.0E-23 T 09-03-2017 IPR011418 AP endonuclease, family 2, C-terminal UA74_RS27235 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 Pfam PF01261 Xylose isomerase-like TIM barrel 22 274 1.5E-36 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS19410 5c361555189783b6e016db6139a362fe 186 Gene3D G3DSA:2.30.110.10 28 179 7.9E-42 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS19410 5c361555189783b6e016db6139a362fe 186 SUPERFAMILY SSF50475 29 181 1.37E-37 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS19410 5c361555189783b6e016db6139a362fe 186 SMART SM00903 39 181 2.0E-36 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 UA74_RS19410 5c361555189783b6e016db6139a362fe 186 Pfam PF01613 Flavin reductase like domain 39 180 2.3E-26 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 UA74_RS13025 bb82f15b8f517f15ea0830d680adbed6 135 Pfam PF02416 mttA/Hcf106 family 4 54 7.6E-14 T 09-03-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 UA74_RS13025 bb82f15b8f517f15ea0830d680adbed6 135 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 98 19.846 T 09-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 UA74_RS29485 d38d2dba11ed3f75da255bc5303c81c3 449 ProSitePatterns PS00217 Sugar transport proteins signature 2. 321 346 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS29485 d38d2dba11ed3f75da255bc5303c81c3 449 ProSitePatterns PS00216 Sugar transport proteins signature 1. 58 74 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS29485 d38d2dba11ed3f75da255bc5303c81c3 449 Pfam PF07690 Major Facilitator Superfamily 248 399 2.6E-13 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS29485 d38d2dba11ed3f75da255bc5303c81c3 449 Pfam PF07690 Major Facilitator Superfamily 13 246 1.8E-17 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS29485 d38d2dba11ed3f75da255bc5303c81c3 449 Gene3D G3DSA:1.20.1250.20 229 398 1.3E-16 T 09-03-2017 UA74_RS29485 d38d2dba11ed3f75da255bc5303c81c3 449 SUPERFAMILY SSF103473 2 399 9.02E-41 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS29485 d38d2dba11ed3f75da255bc5303c81c3 449 Gene3D G3DSA:1.20.1250.20 2 188 3.1E-16 T 09-03-2017 UA74_RS19735 7f7112939d41a657e1066f2023fa193f 630 Pfam PF04055 Radical SAM superfamily 271 429 9.7E-10 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS19735 7f7112939d41a657e1066f2023fa193f 630 Gene3D G3DSA:3.80.30.20 264 453 2.4E-21 T 09-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe UA74_RS19735 7f7112939d41a657e1066f2023fa193f 630 Pfam PF02310 B12 binding domain 122 200 1.1E-9 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS19735 7f7112939d41a657e1066f2023fa193f 630 TIGRFAM TIGR03975 rSAM_ocin_1: ribosomal peptide maturation radical SAM protein 1 3 602 1.8E-191 T 09-03-2017 IPR023984 Ribosomal peptide maturation radical SAM protein 1 UA74_RS19735 7f7112939d41a657e1066f2023fa193f 630 SMART SM00729 264 477 3.0E-21 T 09-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 UA74_RS19735 7f7112939d41a657e1066f2023fa193f 630 SUPERFAMILY SSF102114 264 488 1.77E-23 T 09-03-2017 UA74_RS02690 228047d40c030e323c30c45e5235ad9f 235 SUPERFAMILY SSF56281 4 226 1.76E-43 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS02690 228047d40c030e323c30c45e5235ad9f 235 Gene3D G3DSA:3.60.15.10 1 223 6.4E-41 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS02690 228047d40c030e323c30c45e5235ad9f 235 Pfam PF00753 Metallo-beta-lactamase superfamily 15 212 8.5E-24 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS02690 228047d40c030e323c30c45e5235ad9f 235 SMART SM00849 17 212 1.5E-26 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS22390 547ac22be514b4119936a501a04456f5 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 9.7E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 9.7E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 9.7E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.7E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 9.7E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 9.7E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 241 3.8E-55 T 09-03-2017 UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 5.5E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 5.5E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 5.5E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22390 547ac22be514b4119936a501a04456f5 249 Gene3D G3DSA:3.40.50.720 2 243 1.6E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22390 547ac22be514b4119936a501a04456f5 249 SUPERFAMILY SSF51735 6 243 7.18E-70 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09015 864db4b7f343056c580fdfab09f3a52c 385 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 293 2.8E-63 T 09-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 UA74_RS09015 864db4b7f343056c580fdfab09f3a52c 385 Gene3D G3DSA:3.40.50.450 125 245 2.3E-14 T 09-03-2017 UA74_RS09015 864db4b7f343056c580fdfab09f3a52c 385 SUPERFAMILY SSF102405 106 299 1.98E-35 T 09-03-2017 UA74_RS09015 864db4b7f343056c580fdfab09f3a52c 385 Pfam PF02481 DNA recombination-mediator protein A 74 292 1.4E-69 T 09-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 UA74_RS21320 df59a2efe95f884bd0cd782cfdf2a924 419 Gene3D G3DSA:3.90.1230.10 218 328 7.8E-42 T 09-03-2017 UA74_RS21320 df59a2efe95f884bd0cd782cfdf2a924 419 Pfam PF02898 Nitric oxide synthase, oxygenase domain 28 385 9.2E-153 T 09-03-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_RS21320 df59a2efe95f884bd0cd782cfdf2a924 419 SUPERFAMILY SSF56512 11 387 1.57E-157 T 09-03-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_RS21320 df59a2efe95f884bd0cd782cfdf2a924 419 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 87 94 - T 09-03-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_RS21320 df59a2efe95f884bd0cd782cfdf2a924 419 PIRSF PIRSF037219 23 391 1.2E-155 T 09-03-2017 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 UA74_RS21320 df59a2efe95f884bd0cd782cfdf2a924 419 Gene3D G3DSA:3.90.340.10 16 156 1.6E-47 T 09-03-2017 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 SUPERFAMILY SSF52317 397 620 2.9E-52 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 Pfam PF08532 Beta-galactosidase trimerisation domain 400 619 1.8E-57 T 09-03-2017 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 SUPERFAMILY SSF51445 17 371 9.78E-114 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 Gene3D G3DSA:3.20.20.80 17 391 3.3E-127 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 PIRSF PIRSF001084 8 693 3.5E-249 T 09-03-2017 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 Pfam PF08533 Beta-galactosidase C-terminal domain 629 690 1.5E-4 T 09-03-2017 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 Pfam PF02449 Beta-galactosidase 20 389 5.7E-146 T 09-03-2017 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_RS23965 bd0dfc8e9f3233e7db1fa19a945fe920 695 Gene3D G3DSA:3.40.50.880 397 622 9.4E-64 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS21050 3bdc937ad421cc8c32c50483d375bf8f 321 Pfam PF01636 Phosphotransferase enzyme family 76 246 1.1E-6 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS21050 3bdc937ad421cc8c32c50483d375bf8f 321 SUPERFAMILY SSF56112 26 285 2.62E-17 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS21050 3bdc937ad421cc8c32c50483d375bf8f 321 Gene3D G3DSA:3.90.1200.10 130 246 3.5E-7 T 09-03-2017 UA74_RS24230 7ff845bfe2562f95d56e8e9562f7f695 325 Pfam PF00106 short chain dehydrogenase 51 247 1.2E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24230 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 229 7.7E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24230 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 137 7.7E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24230 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 248 7.7E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24230 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 50 67 7.7E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24230 7ff845bfe2562f95d56e8e9562f7f695 325 SUPERFAMILY SSF51735 46 308 3.1E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24230 7ff845bfe2562f95d56e8e9562f7f695 325 Gene3D G3DSA:3.40.50.720 40 289 2.4E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 SUPERFAMILY SSF46609 3 88 4.06E-26 T 09-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 09-03-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 PIRSF PIRSF000349 1 200 9.5E-65 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 3.4E-26 T 09-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 5.0E-18 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 5.0E-18 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 5.0E-18 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 5.0E-18 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 5.0E-18 T 09-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 Gene3D G3DSA:1.10.287.990 23 83 9.7E-20 T 09-03-2017 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 191 4.9E-32 T 09-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS20535 03874e0e457876a92a3c522a72c92322 207 SUPERFAMILY SSF54719 86 196 4.58E-40 T 09-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 09-03-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 Gene3D G3DSA:3.20.20.80 2 480 7.7E-144 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 446 458 2.0E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 401 412 2.0E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 359 367 2.0E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 285 299 2.0E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 422 439 2.0E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 SUPERFAMILY SSF51445 2 368 3.63E-144 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 SUPERFAMILY SSF51445 399 476 3.63E-144 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS11880 babed4e07a90b5d0b784fa92f79188c0 488 Pfam PF00232 Glycosyl hydrolase family 1 2 475 9.7E-136 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS18750 ab7416770fa5da2b8129c7ecc38f9e4f 233 SUPERFAMILY SSF52518 27 227 9.09E-50 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS18750 ab7416770fa5da2b8129c7ecc38f9e4f 233 Gene3D G3DSA:3.40.50.970 27 227 1.3E-49 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS18750 ab7416770fa5da2b8129c7ecc38f9e4f 233 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 27 224 3.1E-28 T 09-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_RS26175 60c6e2e2bbcc56de7473cb514acf6fca 684 Pfam PF00069 Protein kinase domain 15 261 4.3E-35 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS26175 60c6e2e2bbcc56de7473cb514acf6fca 684 SUPERFAMILY SSF56112 11 267 1.75E-61 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS26175 60c6e2e2bbcc56de7473cb514acf6fca 684 Gene3D G3DSA:3.30.200.20 7 89 1.7E-16 T 09-03-2017 UA74_RS26175 60c6e2e2bbcc56de7473cb514acf6fca 684 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS26175 60c6e2e2bbcc56de7473cb514acf6fca 684 Gene3D G3DSA:1.10.510.10 97 329 1.7E-36 T 09-03-2017 UA74_RS26175 60c6e2e2bbcc56de7473cb514acf6fca 684 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 133 145 - T 09-03-2017 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS17845 8b04dc02d5449f60f577bf87f22849af 297 SMART SM00382 26 204 1.9E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS17845 8b04dc02d5449f60f577bf87f22849af 297 SUPERFAMILY SSF52540 2 217 4.66E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17845 8b04dc02d5449f60f577bf87f22849af 297 Gene3D G3DSA:3.40.50.300 1 220 2.4E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17845 8b04dc02d5449f60f577bf87f22849af 297 Pfam PF00005 ABC transporter 18 156 1.2E-25 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16950 b2a458e09b1a64cf39da082e5f8b5d20 195 Pfam PF04191 Phospholipid methyltransferase 71 168 1.2E-4 T 09-03-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 UA74_RS21415 dc7708bc1ef6b8f6a9e57c87bf955c08 340 SUPERFAMILY SSF81345 5 335 2.75E-75 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS21415 dc7708bc1ef6b8f6a9e57c87bf955c08 340 Pfam PF01032 FecCD transport family 19 335 1.0E-84 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS21415 dc7708bc1ef6b8f6a9e57c87bf955c08 340 Gene3D G3DSA:1.10.3470.10 10 339 4.1E-95 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS20720 e1fa5eb894db9c507caca8a28cea91c8 200 Gene3D G3DSA:3.40.50.10420 29 197 1.6E-52 T 09-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain UA74_RS20720 e1fa5eb894db9c507caca8a28cea91c8 200 SUPERFAMILY SSF100950 29 197 1.0E-37 T 09-03-2017 UA74_RS20720 e1fa5eb894db9c507caca8a28cea91c8 200 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 98 197 6.7E-21 T 09-03-2017 IPR003741 LUD domain UA74_RS10420 4aaa44cb8e0abc896d6f8b70b5f0a90a 116 Pfam PF13453 Transcription factor zinc-finger 3 41 3.0E-17 T 09-03-2017 IPR027392 Transcription factor zinc-finger UA74_RS10745 b5f28dd244142f4b5f700659ecb8d678 678 Pfam PF01757 Acyltransferase family 21 351 1.2E-20 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS12010 350b6e7f3bf0b98beb757e29ca15a4d1 330 Gene3D G3DSA:3.40.50.970 4 193 7.5E-78 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12010 350b6e7f3bf0b98beb757e29ca15a4d1 330 SMART SM00861 4 179 3.1E-61 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS12010 350b6e7f3bf0b98beb757e29ca15a4d1 330 SUPERFAMILY SSF52518 4 203 2.12E-68 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12010 350b6e7f3bf0b98beb757e29ca15a4d1 330 Pfam PF02780 Transketolase, C-terminal domain 193 314 1.1E-39 T 09-03-2017 IPR033248 Transketolase, C-terminal domain UA74_RS12010 350b6e7f3bf0b98beb757e29ca15a4d1 330 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 9.5E-44 T 09-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_RS12010 350b6e7f3bf0b98beb757e29ca15a4d1 330 SUPERFAMILY SSF52922 190 323 6.94E-41 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS12010 350b6e7f3bf0b98beb757e29ca15a4d1 330 Gene3D G3DSA:3.40.50.920 194 323 4.7E-45 T 09-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 UA74_RS05680 6434b00d669e59eeb758082c6f4ebd72 274 Gene3D G3DSA:1.10.580.10 15 61 1.5E-8 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS05680 6434b00d669e59eeb758082c6f4ebd72 274 Pfam PF00285 Citrate synthase, C-terminal domain 55 246 3.9E-27 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS05680 6434b00d669e59eeb758082c6f4ebd72 274 Pfam PF00285 Citrate synthase, C-terminal domain 14 59 5.9E-6 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS05680 6434b00d669e59eeb758082c6f4ebd72 274 SUPERFAMILY SSF48256 4 251 1.7E-48 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS05680 6434b00d669e59eeb758082c6f4ebd72 274 Gene3D G3DSA:1.10.580.10 62 168 2.1E-18 T 09-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_RS12625 a7ad1e832cc325f410fe81df61f017ff 256 Gene3D G3DSA:3.40.50.300 3 234 6.3E-45 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12625 a7ad1e832cc325f410fe81df61f017ff 256 Pfam PF00005 ABC transporter 23 174 2.8E-20 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS12625 a7ad1e832cc325f410fe81df61f017ff 256 SMART SM00382 32 225 3.9E-6 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS12625 a7ad1e832cc325f410fe81df61f017ff 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 1.6E-103 T 09-03-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 UA74_RS12625 a7ad1e832cc325f410fe81df61f017ff 256 SUPERFAMILY SSF52540 4 234 4.18E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 SUPERFAMILY SSF48452 505 691 3.13E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 PRINTS PR00364 Disease resistance protein signature 160 174 1.0E-9 T 09-03-2017 UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 PRINTS PR00364 Disease resistance protein signature 248 262 1.0E-9 T 09-03-2017 UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 PRINTS PR00364 Disease resistance protein signature 82 97 1.0E-9 T 09-03-2017 UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 Gene3D G3DSA:3.40.50.300 68 180 2.1E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 SUPERFAMILY SSF52540 47 309 1.37E-24 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 Gene3D G3DSA:1.25.40.10 561 696 2.5E-15 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS20675 66606712e6e43938a176e8c6373b6483 714 Pfam PF00931 NB-ARC domain 69 280 8.4E-7 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 177 205 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 51 281 8.9E-53 T 09-03-2017 UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 190 209 4.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 129 4.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 178 4.5E-7 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 Gene3D G3DSA:3.40.50.720 38 282 1.5E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 1.3E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 1.3E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 1.3E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 1.3E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 265 1.3E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 1.3E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07870 f36d201bac3aaeb8d9cd0f38979b3bbe 286 SUPERFAMILY SSF51735 41 283 3.1E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14995 236a1d6be85fe672d429ce87fb06e1e3 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 190 8.4E-9 T 09-03-2017 IPR023214 HAD-like domain UA74_RS14995 236a1d6be85fe672d429ce87fb06e1e3 220 Gene3D G3DSA:3.40.50.1000 2 206 1.3E-25 T 09-03-2017 IPR023214 HAD-like domain UA74_RS14995 236a1d6be85fe672d429ce87fb06e1e3 220 SUPERFAMILY SSF56784 1 202 9.03E-26 T 09-03-2017 IPR023214 HAD-like domain UA74_RS20400 ce8221e14518204c57fb739ca40faab2 343 Pfam PF01032 FecCD transport family 31 337 3.7E-85 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS20400 ce8221e14518204c57fb739ca40faab2 343 Gene3D G3DSA:1.10.3470.10 18 338 3.2E-97 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS20400 ce8221e14518204c57fb739ca40faab2 343 SUPERFAMILY SSF81345 16 337 1.44E-75 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS12955 91fe5d8e14447eb5822f95b98bfeb072 167 Pfam PF12079 Protein of unknown function (DUF3558) 10 166 1.2E-10 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 Gene3D G3DSA:1.10.630.10 16 400 1.3E-102 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 192 214 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 291 318 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 156 171 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 273 284 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 319 334 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 340 349 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 349 360 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 139 155 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 PRINTS PR00359 B-class P450 signature 92 103 1.0E-49 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 Pfam PF00067 Cytochrome P450 208 370 7.1E-17 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS23065 c219752b117642778609fe06ab6424f5 400 SUPERFAMILY SSF48264 19 400 3.93E-77 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS11675 1da9e41b2838471c66849a6daf7ddbf6 199 Gene3D G3DSA:1.10.357.10 4 193 3.4E-32 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS11675 1da9e41b2838471c66849a6daf7ddbf6 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 7.5E-16 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS11675 1da9e41b2838471c66849a6daf7ddbf6 199 SUPERFAMILY SSF46689 6 86 1.3E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11675 1da9e41b2838471c66849a6daf7ddbf6 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.8E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS11675 1da9e41b2838471c66849a6daf7ddbf6 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.8E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS11675 1da9e41b2838471c66849a6daf7ddbf6 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 63 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 SUPERFAMILY SSF109998 246 434 9.81E-41 T 09-03-2017 IPR027304 Trigger factor/SurA domain UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 SUPERFAMILY SSF102735 2 128 5.49E-31 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 PIRSF PIRSF003095 1 443 6.8E-108 T 09-03-2017 IPR005215 Trigger factor GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 Pfam PF05697 Bacterial trigger factor protein (TF) 2 145 8.7E-37 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 TIGRFAM TIGR00115 tig: trigger factor 12 415 1.3E-111 T 09-03-2017 IPR005215 Trigger factor GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 415 6.0E-33 T 09-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 Hamap MF_00303 Trigger factor [tig]. 1 424 18.515 T 09-03-2017 IPR005215 Trigger factor GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 Gene3D G3DSA:3.30.70.1050 2 119 1.1E-31 T 09-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 Gene3D G3DSA:3.10.50.40 159 212 1.3E-12 T 09-03-2017 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 Gene3D G3DSA:1.10.3120.10 213 391 1.4E-40 T 09-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 UA74_RS08165 1f1a7d615371352efe0160dc744cabfb 477 SUPERFAMILY SSF54534 133 244 5.3E-19 T 09-03-2017 UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 406 5.1E-115 T 09-03-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 Pfam PF01842 ACT domain 268 329 1.0E-10 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 Pfam PF13840 ACT domain 341 403 2.8E-15 T 09-03-2017 IPR027795 GATS-like ACT domain UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 Gene3D G3DSA:3.40.1160.10 3 246 7.1E-72 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 PIRSF PIRSF000726 59 414 1.5E-124 T 09-03-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 SUPERFAMILY SSF55021 251 330 2.05E-17 T 09-03-2017 UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 SUPERFAMILY SSF55021 334 408 9.92E-22 T 09-03-2017 UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 09-03-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 Pfam PF00696 Amino acid kinase family 3 231 6.9E-53 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS01070 ceddd35172fdca5be38deae952df0589 421 SUPERFAMILY SSF53633 4 244 1.11E-70 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS11140 701f8a617b9d7a8122298b45cef3cfe3 180 Gene3D G3DSA:3.10.180.10 53 178 8.6E-20 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS11140 701f8a617b9d7a8122298b45cef3cfe3 180 SUPERFAMILY SSF54593 51 179 1.29E-18 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS05200 10fab9a81f31992d7566f8b69c5e5712 577 Pfam PF00664 ABC transporter transmembrane region 36 301 4.2E-25 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS05200 10fab9a81f31992d7566f8b69c5e5712 577 Gene3D G3DSA:1.20.1560.10 21 331 5.2E-42 T 09-03-2017 UA74_RS05200 10fab9a81f31992d7566f8b69c5e5712 577 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS05200 10fab9a81f31992d7566f8b69c5e5712 577 SUPERFAMILY SSF52540 354 568 2.08E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05200 10fab9a81f31992d7566f8b69c5e5712 577 SUPERFAMILY SSF90123 19 331 1.03E-46 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS05200 10fab9a81f31992d7566f8b69c5e5712 577 Pfam PF00005 ABC transporter 382 496 3.4E-7 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS05200 10fab9a81f31992d7566f8b69c5e5712 577 Gene3D G3DSA:3.40.50.300 385 570 3.8E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17555 1c4d74632eae31d03c4294fa51b67dd0 118 SMART SM00418 8 86 1.9E-19 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS17555 1c4d74632eae31d03c4294fa51b67dd0 118 Pfam PF12840 Helix-turn-helix domain 8 62 7.3E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17555 1c4d74632eae31d03c4294fa51b67dd0 118 SUPERFAMILY SSF46785 4 99 3.22E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS17555 1c4d74632eae31d03c4294fa51b67dd0 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.2E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS17555 1c4d74632eae31d03c4294fa51b67dd0 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 2.2E-8 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS17555 1c4d74632eae31d03c4294fa51b67dd0 118 Gene3D G3DSA:1.10.10.10 2 106 2.4E-31 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07640 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 Pfam PF00248 Aldo/keto reductase family 16 318 2.8E-62 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS07640 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 Gene3D G3DSA:3.20.20.100 3 322 2.9E-90 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS07640 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 SUPERFAMILY SSF51430 3 319 1.7E-81 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS07640 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 PRINTS PR00069 Aldo-keto reductase signature 122 140 1.8E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07640 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 PRINTS PR00069 Aldo-keto reductase signature 252 276 1.8E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS07640 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 PRINTS PR00069 Aldo-keto reductase signature 153 170 1.8E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS11885 86f1c76afc67736c61a9b8eb969a5e3e 328 SUPERFAMILY SSF51735 5 160 3.29E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11885 86f1c76afc67736c61a9b8eb969a5e3e 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 124 1.0E-23 T 09-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_RS11885 86f1c76afc67736c61a9b8eb969a5e3e 328 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 140 203 3.7E-4 T 09-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 UA74_RS11885 86f1c76afc67736c61a9b8eb969a5e3e 328 Gene3D G3DSA:3.40.50.720 5 147 1.4E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11885 86f1c76afc67736c61a9b8eb969a5e3e 328 SUPERFAMILY SSF55347 132 292 2.62E-37 T 09-03-2017 UA74_RS11885 86f1c76afc67736c61a9b8eb969a5e3e 328 Gene3D G3DSA:3.30.360.10 148 324 1.3E-46 T 09-03-2017 UA74_RS26255 b4b75ec1eee42c2d8bf65b6f1a83f34b 377 Pfam PF03235 Protein of unknown function DUF262 43 114 3.6E-14 T 09-03-2017 IPR004919 Domain of unknown function DUF262 UA74_RS15375 f97feb8b9b8a881edfc1fbde20724523 208 Gene3D G3DSA:3.40.50.720 2 202 3.4E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15375 f97feb8b9b8a881edfc1fbde20724523 208 Pfam PF13460 NAD(P)H-binding 7 198 1.3E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15375 f97feb8b9b8a881edfc1fbde20724523 208 SUPERFAMILY SSF51735 2 201 1.72E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS04450 bfdd8b8e724aabf111e17fad7cc01d49 340 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 3 328 31.764 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS04450 bfdd8b8e724aabf111e17fad7cc01d49 340 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 7 327 3.7E-94 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS04450 bfdd8b8e724aabf111e17fad7cc01d49 340 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 38 322 2.5E-87 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS04450 bfdd8b8e724aabf111e17fad7cc01d49 340 Gene3D G3DSA:3.40.718.10 3 328 1.7E-106 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS04450 bfdd8b8e724aabf111e17fad7cc01d49 340 SUPERFAMILY SSF53659 5 328 4.07E-97 T 09-03-2017 UA74_RS21185 a8459373e39ca6902f44758c2b3e88af 300 SUPERFAMILY SSF103481 175 276 1.14E-14 T 09-03-2017 UA74_RS21185 a8459373e39ca6902f44758c2b3e88af 300 SUPERFAMILY SSF103481 30 130 3.14E-12 T 09-03-2017 UA74_RS21185 a8459373e39ca6902f44758c2b3e88af 300 Pfam PF00892 EamA-like transporter family 139 272 3.4E-22 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS21185 a8459373e39ca6902f44758c2b3e88af 300 Pfam PF00892 EamA-like transporter family 2 126 7.7E-17 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS01880 b13e019e997e080be99a834cf3a7128d 288 SUPERFAMILY SSF53613 18 282 4.37E-71 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS01880 b13e019e997e080be99a834cf3a7128d 288 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 21 279 1.5E-83 T 09-03-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_RS01880 b13e019e997e080be99a834cf3a7128d 288 Gene3D G3DSA:3.40.1190.20 19 279 4.2E-88 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS01880 b13e019e997e080be99a834cf3a7128d 288 Pfam PF08543 Phosphomethylpyrimidine kinase 28 277 5.0E-81 T 09-03-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 UA74_RS19065 c2d0c959973adbf769f79992312750ef 159 Gene3D G3DSA:3.10.129.10 15 142 9.4E-21 T 09-03-2017 IPR029069 HotDog domain UA74_RS19065 c2d0c959973adbf769f79992312750ef 159 Pfam PF03061 Thioesterase superfamily 32 114 2.6E-7 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 UA74_RS19065 c2d0c959973adbf769f79992312750ef 159 SUPERFAMILY SSF54637 15 143 3.87E-20 T 09-03-2017 IPR029069 HotDog domain UA74_RS01210 73413774acd58b9a3654ef078cddc551 273 SUPERFAMILY SSF56281 30 272 3.28E-49 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS01210 73413774acd58b9a3654ef078cddc551 273 Gene3D G3DSA:3.60.15.10 26 231 1.1E-43 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS01210 73413774acd58b9a3654ef078cddc551 273 Pfam PF00753 Metallo-beta-lactamase superfamily 39 201 4.0E-18 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS01210 73413774acd58b9a3654ef078cddc551 273 SMART SM00849 40 201 6.2E-24 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS21990 e340751b1d935748955568ffaf496639 199 Gene3D G3DSA:1.10.10.60 7 54 1.7E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS21990 e340751b1d935748955568ffaf496639 199 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 184 1.2E-12 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS21990 e340751b1d935748955568ffaf496639 199 Gene3D G3DSA:1.10.357.10 57 189 1.5E-14 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS21990 e340751b1d935748955568ffaf496639 199 SUPERFAMILY SSF48498 78 188 6.0E-8 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS21990 e340751b1d935748955568ffaf496639 199 SUPERFAMILY SSF46689 5 67 1.39E-8 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS21990 e340751b1d935748955568ffaf496639 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 5.4E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS10410 6318089d6b01c7d43da1efa0dec3a3a1 476 Gene3D G3DSA:3.80.30.10 130 292 1.2E-30 T 09-03-2017 UA74_RS10410 6318089d6b01c7d43da1efa0dec3a3a1 476 Pfam PF04055 Radical SAM superfamily 88 241 1.5E-12 T 09-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_RS10410 6318089d6b01c7d43da1efa0dec3a3a1 476 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 16 338 2.4E-88 T 09-03-2017 IPR027596 AmmeMemoRadiSam system radical SAM enzyme UA74_RS10410 6318089d6b01c7d43da1efa0dec3a3a1 476 SUPERFAMILY SSF102114 86 319 1.7E-27 T 09-03-2017 UA74_RS16600 b9c8ff0070c035d79a8bacd2cc68f717 507 SUPERFAMILY SSF53822 123 476 2.94E-17 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS16600 b9c8ff0070c035d79a8bacd2cc68f717 507 Gene3D G3DSA:3.40.50.2300 138 271 4.8E-9 T 09-03-2017 UA74_RS16600 b9c8ff0070c035d79a8bacd2cc68f717 507 Pfam PF01094 Receptor family ligand binding region 132 473 2.5E-6 T 09-03-2017 IPR001828 Receptor, ligand binding region UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.1E-30 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 SUPERFAMILY SSF50249 1 66 7.93E-25 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 SMART SM00357 3 67 8.5E-29 T 09-03-2017 IPR011129 Cold shock protein GO:0003676 UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 09-03-2017 IPR019844 Cold-shock conserved site UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 PIRSF PIRSF002599 1 67 2.6E-24 T 09-03-2017 IPR012156 Cold shock, CspA GO:0003676 UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 PRINTS PR00050 Cold shock protein signature 25 34 1.8E-16 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 PRINTS PR00050 Cold shock protein signature 4 19 1.8E-16 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 PRINTS PR00050 Cold shock protein signature 40 58 1.8E-16 T 09-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_RS07930 a38a45b967b82989fc0a06db888c0999 67 Gene3D G3DSA:2.40.50.140 1 66 4.3E-31 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS08510 20300e241d23fff174b71dd5b3be3e97 387 SUPERFAMILY SSF53067 84 381 1.35E-43 T 09-03-2017 UA74_RS08510 20300e241d23fff174b71dd5b3be3e97 387 Gene3D G3DSA:1.10.10.10 10 76 6.9E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08510 20300e241d23fff174b71dd5b3be3e97 387 Gene3D G3DSA:3.30.420.40 219 359 2.4E-36 T 09-03-2017 UA74_RS08510 20300e241d23fff174b71dd5b3be3e97 387 Gene3D G3DSA:3.30.420.40 80 218 6.8E-32 T 09-03-2017 UA74_RS08510 20300e241d23fff174b71dd5b3be3e97 387 Pfam PF00480 ROK family 85 379 2.4E-49 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS08510 20300e241d23fff174b71dd5b3be3e97 387 SUPERFAMILY SSF46785 10 74 2.15E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26370 3c0c6901f389c62c1d3040dc8755b693 537 SUPERFAMILY SSF52096 239 518 1.02E-88 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS26370 3c0c6901f389c62c1d3040dc8755b693 537 SUPERFAMILY SSF52096 26 273 1.31E-69 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS26370 3c0c6901f389c62c1d3040dc8755b693 537 Gene3D G3DSA:3.90.226.10 281 528 2.9E-95 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS26370 3c0c6901f389c62c1d3040dc8755b693 537 Gene3D G3DSA:3.90.226.10 31 277 1.7E-79 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS26370 3c0c6901f389c62c1d3040dc8755b693 537 Pfam PF01039 Carboxyl transferase domain 50 527 4.6E-150 T 09-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_RS05260 0932af5860b7df03ff4d7b9b49781757 384 Gene3D G3DSA:3.40.640.10 53 252 4.0E-52 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS05260 0932af5860b7df03ff4d7b9b49781757 384 SUPERFAMILY SSF53383 49 379 7.21E-73 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS05260 0932af5860b7df03ff4d7b9b49781757 384 Gene3D G3DSA:3.90.1150.10 253 379 3.4E-17 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS05260 0932af5860b7df03ff4d7b9b49781757 384 Pfam PF00155 Aminotransferase class I and II 55 363 1.0E-38 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS18365 5a95780e7247ed7eeea98bcc634c1584 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 16 146 4.9E-12 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS18365 5a95780e7247ed7eeea98bcc634c1584 153 SUPERFAMILY SSF55961 17 146 9.47E-18 T 09-03-2017 UA74_RS18365 5a95780e7247ed7eeea98bcc634c1584 153 Gene3D G3DSA:3.30.530.20 16 140 1.6E-6 T 09-03-2017 IPR023393 START-like domain UA74_RS19260 b1a5c2679132d5e4ed6182f24d1c2778 510 Pfam PF00361 Proton-conducting membrane transporter 126 413 8.3E-48 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS19260 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 369 395 2.9E-7 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS19260 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 2.9E-7 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS19260 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 131 150 2.9E-7 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS19260 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 317 336 2.9E-7 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS25460 5e53120a8daeb79ff580febebd13b96d 1401 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 6 1395 1.9E-201 T 09-03-2017 IPR013496 Conserved hypothetical protein CHP02680 UA74_RS25460 5e53120a8daeb79ff580febebd13b96d 1401 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1254 1347 4.1E-19 T 09-03-2017 UA74_RS25460 5e53120a8daeb79ff580febebd13b96d 1401 Gene3D G3DSA:3.40.1140.10 5 97 2.5E-18 T 09-03-2017 UA74_RS25460 5e53120a8daeb79ff580febebd13b96d 1401 Gene3D G3DSA:3.40.1140.10 1284 1351 2.5E-18 T 09-03-2017 UA74_RS25460 5e53120a8daeb79ff580febebd13b96d 1401 SUPERFAMILY SSF52540 19 87 1.29E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25460 5e53120a8daeb79ff580febebd13b96d 1401 SUPERFAMILY SSF52540 197 307 1.29E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25460 5e53120a8daeb79ff580febebd13b96d 1401 SUPERFAMILY SSF52540 1258 1349 1.29E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17045 e91263ebaed0a56e14e369fa14093235 103 SUPERFAMILY SSF54292 18 98 8.59E-15 T 09-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 UA74_RS17045 e91263ebaed0a56e14e369fa14093235 103 Gene3D G3DSA:3.10.20.30 32 88 5.7E-5 T 09-03-2017 IPR012675 Beta-grasp domain UA74_RS17045 e91263ebaed0a56e14e369fa14093235 103 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 94 5.2E-21 T 09-03-2017 UA74_RS16865 6ec5b575075b0de01f66725678872603 302 Gene3D G3DSA:3.40.50.720 13 230 2.9E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16865 6ec5b575075b0de01f66725678872603 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.2E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16865 6ec5b575075b0de01f66725678872603 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.2E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16865 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16865 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16865 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16865 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.1E-14 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16865 6ec5b575075b0de01f66725678872603 302 Pfam PF00106 short chain dehydrogenase 16 206 3.3E-23 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS16865 6ec5b575075b0de01f66725678872603 302 SUPERFAMILY SSF51735 13 241 7.74E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15380 2e3ded12c92a899e8dbf08bb318a7db5 347 Gene3D G3DSA:3.30.565.10 260 342 9.3E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS15380 2e3ded12c92a899e8dbf08bb318a7db5 347 Pfam PF07730 Histidine kinase 147 207 5.3E-11 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS15380 2e3ded12c92a899e8dbf08bb318a7db5 347 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 342 1.1E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS15380 2e3ded12c92a899e8dbf08bb318a7db5 347 SMART SM00387 254 345 4.4E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS15380 2e3ded12c92a899e8dbf08bb318a7db5 347 SUPERFAMILY SSF55874 249 342 1.86E-16 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07730 81391d70ae08926f089910613b27b1a9 161 SUPERFAMILY SSF101386 36 145 6.98E-28 T 09-03-2017 UA74_RS07730 81391d70ae08926f089910613b27b1a9 161 Gene3D G3DSA:1.10.287.1080 29 125 1.8E-21 T 09-03-2017 UA74_RS07730 81391d70ae08926f089910613b27b1a9 161 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 54 132 4.1E-7 T 09-03-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 Gene3D G3DSA:3.40.710.10 62 315 2.7E-95 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 Pfam PF13354 Beta-lactamase enzyme family 83 288 2.4E-35 T 09-03-2017 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 93 110 3.7E-66 T 09-03-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 169 193 3.7E-66 T 09-03-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 248 263 3.7E-66 T 09-03-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 133 158 3.7E-66 T 09-03-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 195 220 3.7E-66 T 09-03-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 231 246 3.7E-66 T 09-03-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 62 86 3.7E-66 T 09-03-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 SUPERFAMILY SSF56601 62 310 5.8E-70 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS19435 6767fce064119c1b1d30529efce509a9 319 ProSitePatterns PS00146 Beta-lactamase class-A active site. 95 110 - T 09-03-2017 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 UA74_RS03050 3fa65aa9a5718601db0985d77891d286 65 Pfam PF04149 Domain of unknown function (DUF397) 7 58 1.5E-14 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS05160 0e5a78037933839566b76f33141d3471 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 43 177 4.3E-9 T 09-03-2017 IPR023214 HAD-like domain UA74_RS05160 0e5a78037933839566b76f33141d3471 214 SUPERFAMILY SSF56784 1 207 2.18E-33 T 09-03-2017 IPR023214 HAD-like domain UA74_RS05160 0e5a78037933839566b76f33141d3471 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 170 1.9E-7 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS05160 0e5a78037933839566b76f33141d3471 214 Gene3D G3DSA:3.40.50.1000 1 209 1.4E-30 T 09-03-2017 IPR023214 HAD-like domain UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 6.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 6.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 6.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 6.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 6.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 6.0E-40 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 Gene3D G3DSA:3.40.50.720 13 261 2.4E-75 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18305 69111173cde22a29813c273db43b3e33 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 258 7.1E-57 T 09-03-2017 UA74_RS18305 69111173cde22a29813c273db43b3e33 275 SUPERFAMILY SSF51735 16 261 1.32E-74 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 1.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 1.2E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18305 69111173cde22a29813c273db43b3e33 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS09750 194c5721ccb02324a15ee6c4fa55e984 285 SMART SM00797 22 282 8.1E-105 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B UA74_RS09750 194c5721ccb02324a15ee6c4fa55e984 285 Pfam PF02626 Allophanate hydrolase subunit 2 23 279 1.6E-84 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B UA74_RS09750 194c5721ccb02324a15ee6c4fa55e984 285 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 279 4.9E-85 T 09-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B UA74_RS09750 194c5721ccb02324a15ee6c4fa55e984 285 SUPERFAMILY SSF50891 172 280 1.1E-13 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS09750 194c5721ccb02324a15ee6c4fa55e984 285 Gene3D G3DSA:2.40.100.10 174 279 1.0E-7 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS07595 6f6ad1089e1893c0cb9e99cdd0179f8b 136 SUPERFAMILY SSF54593 3 134 3.49E-25 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS07595 6f6ad1089e1893c0cb9e99cdd0179f8b 136 Gene3D G3DSA:3.10.180.10 1 134 7.8E-29 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS07595 6f6ad1089e1893c0cb9e99cdd0179f8b 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 2.3E-13 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS10720 a474ca2da14dc098934515fd611de7f8 242 Gene3D G3DSA:3.40.50.300 6 135 1.2E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10720 a474ca2da14dc098934515fd611de7f8 242 Pfam PF00005 ABC transporter 24 75 1.2E-5 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS10720 a474ca2da14dc098934515fd611de7f8 242 SUPERFAMILY SSF52540 5 166 3.88E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18485 9fa9fa88847ed70c911f8fc491937ddf 221 Pfam PF00156 Phosphoribosyl transferase domain 13 199 4.1E-23 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_RS18485 9fa9fa88847ed70c911f8fc491937ddf 221 SUPERFAMILY SSF53271 7 211 1.79E-43 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS18485 9fa9fa88847ed70c911f8fc491937ddf 221 Gene3D G3DSA:3.40.50.2020 98 207 1.4E-36 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS18485 9fa9fa88847ed70c911f8fc491937ddf 221 Gene3D G3DSA:3.40.50.2020 10 66 1.4E-36 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS28415 9e6955f3ba4256d4db7bd37a57013483 308 Gene3D G3DSA:2.70.98.10 9 305 6.7E-42 T 09-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 UA74_RS28415 9e6955f3ba4256d4db7bd37a57013483 308 Pfam PF01263 Aldose 1-epimerase 15 302 2.1E-40 T 09-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 UA74_RS28415 9e6955f3ba4256d4db7bd37a57013483 308 SUPERFAMILY SSF74650 12 305 2.64E-57 T 09-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 UA74_RS10470 17de904219cbddb497dfa54e49776804 294 Pfam PF00535 Glycosyl transferase family 2 7 164 2.0E-19 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS10470 17de904219cbddb497dfa54e49776804 294 Gene3D G3DSA:3.90.550.10 5 232 2.2E-26 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS10470 17de904219cbddb497dfa54e49776804 294 SUPERFAMILY SSF53448 3 231 3.84E-37 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS17725 59d8d94c7d6fc23e7b4ec0edbe0c063e 448 Pfam PF07690 Major Facilitator Superfamily 21 369 2.5E-23 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS17725 59d8d94c7d6fc23e7b4ec0edbe0c063e 448 SUPERFAMILY SSF103473 12 404 1.57E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS17725 59d8d94c7d6fc23e7b4ec0edbe0c063e 448 Gene3D G3DSA:1.20.1250.20 13 200 4.1E-20 T 09-03-2017 UA74_RS17725 59d8d94c7d6fc23e7b4ec0edbe0c063e 448 Gene3D G3DSA:1.20.1250.20 233 404 1.5E-6 T 09-03-2017 UA74_RS01910 569caa2afdf9fbbcddf38871268a9c6b 227 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 17 220 9.7E-60 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_RS01910 569caa2afdf9fbbcddf38871268a9c6b 227 SUPERFAMILY SSF51391 12 222 3.92E-59 T 09-03-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_RS01910 569caa2afdf9fbbcddf38871268a9c6b 227 Gene3D G3DSA:3.20.20.70 9 225 1.2E-71 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS01910 569caa2afdf9fbbcddf38871268a9c6b 227 Pfam PF02581 Thiamine monophosphate synthase/TENI 18 207 2.6E-50 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_RS01910 569caa2afdf9fbbcddf38871268a9c6b 227 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 15 225 25.158 T 09-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_RS19980 e14fefc9f42664ee493bda172ebc8890 1183 Pfam PF13569 Domain of unknown function (DUF4132) 889 1096 2.5E-45 T 09-03-2017 IPR025406 Domain of unknown function DUF4132 UA74_RS07155 a265b6c7a09b0570426793b8598dca88 183 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 28 174 2.8E-30 T 09-03-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 UA74_RS07155 a265b6c7a09b0570426793b8598dca88 183 Hamap MF_01398 ATP synthase subunit b [atpF]. 4 174 12.937 T 09-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UA74_RS07155 a265b6c7a09b0570426793b8598dca88 183 Pfam PF00430 ATP synthase B/B' CF(0) 24 152 2.6E-30 T 09-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UA74_RS07155 a265b6c7a09b0570426793b8598dca88 183 Gene3D G3DSA:1.20.5.620 80 138 1.5E-16 T 09-03-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain UA74_RS07155 a265b6c7a09b0570426793b8598dca88 183 SUPERFAMILY SSF81573 80 138 1.02E-13 T 09-03-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain UA74_RS13690 475f6540236e52b00056c16821d19017 365 Gene3D G3DSA:3.40.50.720 186 304 5.3E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13690 475f6540236e52b00056c16821d19017 365 Pfam PF00107 Zinc-binding dehydrogenase 193 315 5.7E-20 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS13690 475f6540236e52b00056c16821d19017 365 Gene3D G3DSA:3.90.180.10 5 185 3.2E-55 T 09-03-2017 IPR011032 GroES-like UA74_RS13690 475f6540236e52b00056c16821d19017 365 SUPERFAMILY SSF50129 7 188 3.8E-47 T 09-03-2017 IPR011032 GroES-like UA74_RS13690 475f6540236e52b00056c16821d19017 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 151 2.0E-25 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS13690 475f6540236e52b00056c16821d19017 365 SUPERFAMILY SSF51735 155 329 2.76E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13690 475f6540236e52b00056c16821d19017 365 SMART SM00829 12 361 1.0E-7 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS18550 09d2c81f77732fe297357883487454ae 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 2.6E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS30300 a006cbc5109fba6af2654116f0f94bf4 129 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 129 29.16 T 09-03-2017 IPR023064 D-ribose pyranase GO:0016872 UA74_RS30300 a006cbc5109fba6af2654116f0f94bf4 129 Pfam PF05025 RbsD / FucU transport protein family 2 127 8.0E-40 T 09-03-2017 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UA74_RS30300 a006cbc5109fba6af2654116f0f94bf4 129 SUPERFAMILY SSF102546 2 129 2.49E-36 T 09-03-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UA74_RS30300 a006cbc5109fba6af2654116f0f94bf4 129 Gene3D G3DSA:3.40.1650.10 3 128 1.4E-27 T 09-03-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UA74_RS29665 ce50eafd5307267855df9f874ecc1e91 316 Gene3D G3DSA:3.30.420.40 1 153 2.3E-32 T 09-03-2017 UA74_RS29665 ce50eafd5307267855df9f874ecc1e91 316 Gene3D G3DSA:3.30.420.40 154 294 1.1E-40 T 09-03-2017 UA74_RS29665 ce50eafd5307267855df9f874ecc1e91 316 Pfam PF00480 ROK family 2 310 1.9E-57 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS29665 ce50eafd5307267855df9f874ecc1e91 316 SUPERFAMILY SSF53067 1 312 1.07E-53 T 09-03-2017 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 SUPERFAMILY SSF54368 8 105 1.44E-28 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 SMART SM01230 106 357 1.1E-126 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 Pfam PF00120 Glutamine synthetase, catalytic domain 107 441 1.4E-126 T 09-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 1.1E-24 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 SUPERFAMILY SSF55931 108 444 9.22E-118 T 09-03-2017 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 09-03-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 Gene3D G3DSA:3.30.590.10 110 435 5.9E-118 T 09-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_RS25305 b0ffdc3ebf9430384b0161a65e1216f5 447 Gene3D G3DSA:3.10.20.70 6 109 1.2E-36 T 09-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_RS05300 9b4cfeef1c533f8c7f4881b972abd34f 312 Pfam PF00005 ABC transporter 20 157 3.4E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS05300 9b4cfeef1c533f8c7f4881b972abd34f 312 Gene3D G3DSA:3.40.50.300 3 227 6.8E-67 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05300 9b4cfeef1c533f8c7f4881b972abd34f 312 SUPERFAMILY SSF52540 3 221 1.51E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05300 9b4cfeef1c533f8c7f4881b972abd34f 312 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS05300 9b4cfeef1c533f8c7f4881b972abd34f 312 SMART SM00382 28 206 8.9E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS24065 42c7a09b969d35ef35d8366e120ea55f 341 Pfam PF07786 Protein of unknown function (DUF1624) 13 107 2.0E-4 T 09-03-2017 IPR012429 Protein of unknown function DUF1624 KEGG: 00531+2.3.1.78|Reactome: R-HSA-2024096|Reactome: R-HSA-2206291 UA74_RS24065 42c7a09b969d35ef35d8366e120ea55f 341 Pfam PF04235 Protein of unknown function (DUF418) 182 317 4.4E-29 T 09-03-2017 IPR007349 Domain of unknown function DUF418 UA74_RS23100 c9d03a3fddf826c0c62cf5c58260d245 352 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 29 94 7.8E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS23100 c9d03a3fddf826c0c62cf5c58260d245 352 Gene3D G3DSA:1.10.10.10 28 113 4.4E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23100 c9d03a3fddf826c0c62cf5c58260d245 352 SUPERFAMILY SSF46785 27 114 9.07E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23580 ab911be2391383dd3b02f3f248cecda0 275 Gene3D G3DSA:3.40.1210.10 2 243 3.0E-46 T 09-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 UA74_RS23580 ab911be2391383dd3b02f3f248cecda0 275 SUPERFAMILY SSF64167 2 242 7.59E-41 T 09-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 UA74_RS23580 ab911be2391383dd3b02f3f248cecda0 275 Pfam PF01975 Survival protein SurE 3 187 2.9E-38 T 09-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 UA74_RS01815 575d5f681a0c95e0d5193e02538ee74b 130 Pfam PF06339 Ectoine synthase 2 125 3.4E-56 T 09-03-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS01815 575d5f681a0c95e0d5193e02538ee74b 130 Gene3D G3DSA:2.60.120.10 33 110 6.6E-14 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS01815 575d5f681a0c95e0d5193e02538ee74b 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 7.0E-39 T 09-03-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS01815 575d5f681a0c95e0d5193e02538ee74b 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 36.852 T 09-03-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS01815 575d5f681a0c95e0d5193e02538ee74b 130 SUPERFAMILY SSF51182 13 125 1.17E-20 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS19490 327263f3feb1283ff57f01414731de68 348 SUPERFAMILY SSF81345 14 341 1.1E-67 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS19490 327263f3feb1283ff57f01414731de68 348 Pfam PF01032 FecCD transport family 33 341 3.0E-75 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS19490 327263f3feb1283ff57f01414731de68 348 Gene3D G3DSA:1.10.3470.10 22 344 4.3E-85 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS21865 e6152cebb6bd5045281a35c2e99ceff2 479 Pfam PF00939 Sodium:sulfate symporter transmembrane region 14 463 7.0E-25 T 09-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UA74_RS19385 50681e3993e3cee15b01e77d674e3b21 334 Gene3D G3DSA:3.40.50.1820 63 314 4.6E-51 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19385 50681e3993e3cee15b01e77d674e3b21 334 SUPERFAMILY SSF53474 60 327 9.7E-40 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19385 50681e3993e3cee15b01e77d674e3b21 334 Pfam PF00756 Putative esterase 73 330 1.6E-55 T 09-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 UA74_RS24880 3f6a80a486195229f868fd1868ffd93f 42 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 40 2.2E-5 T 09-03-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family UA74_RS24880 3f6a80a486195229f868fd1868ffd93f 42 SUPERFAMILY SSF143011 6 42 2.88E-9 T 09-03-2017 UA74_RS13045 6a35fc9a4af8faaf3aa485ab267917ce 404 Pfam PF13527 Acetyltransferase (GNAT) domain 6 131 1.8E-22 T 09-03-2017 UA74_RS13045 6a35fc9a4af8faaf3aa485ab267917ce 404 Gene3D G3DSA:3.40.630.30 144 286 3.0E-21 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS13045 6a35fc9a4af8faaf3aa485ab267917ce 404 SUPERFAMILY SSF55718 300 404 1.37E-16 T 09-03-2017 IPR003033 SCP2 sterol-binding domain UA74_RS13045 6a35fc9a4af8faaf3aa485ab267917ce 404 Gene3D G3DSA:3.30.1050.10 301 392 8.5E-14 T 09-03-2017 IPR003033 SCP2 sterol-binding domain UA74_RS13045 6a35fc9a4af8faaf3aa485ab267917ce 404 Gene3D G3DSA:3.40.630.30 4 133 3.7E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS13045 6a35fc9a4af8faaf3aa485ab267917ce 404 SUPERFAMILY SSF55729 5 299 1.02E-49 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS13045 6a35fc9a4af8faaf3aa485ab267917ce 404 Pfam PF13530 Sterol carrier protein domain 180 400 1.1E-45 T 09-03-2017 IPR025559 Enhanced intracellular survival protein domain UA74_RS16080 3c062651d5916a21ba4cbc0d2915d125 344 Gene3D G3DSA:1.25.40.10 130 293 8.5E-13 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS16080 3c062651d5916a21ba4cbc0d2915d125 344 SUPERFAMILY SSF48452 130 276 5.92E-12 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.40.1010.10 8 116 2.5E-31 T 09-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 09-03-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 SUPERFAMILY SSF69618 238 489 7.46E-70 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 Pfam PF02602 Uroporphyrinogen-III synthase HemD 252 482 1.9E-66 T 09-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.40.50.10090 244 365 2.6E-39 T 09-03-2017 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.40.50.10090 372 489 2.6E-34 T 09-03-2017 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 SUPERFAMILY SSF53790 6 241 1.27E-48 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 203 9.4E-38 T 09-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS02310 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.30.950.10 119 243 1.0E-29 T 09-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 UA74_RS14415 007cfa0383c043f1f2d9bf2306561208 120 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 50 70 - T 09-03-2017 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 UA74_RS14415 007cfa0383c043f1f2d9bf2306561208 120 PIRSF PIRSF002030 1 118 1.0E-39 T 09-03-2017 IPR016339 Truncated hemoglobin, group 1 UA74_RS14415 007cfa0383c043f1f2d9bf2306561208 120 SUPERFAMILY SSF46458 2 116 2.12E-35 T 09-03-2017 IPR009050 Globin-like UA74_RS14415 007cfa0383c043f1f2d9bf2306561208 120 Pfam PF01152 Bacterial-like globin 3 115 1.3E-26 T 09-03-2017 IPR001486 Truncated hemoglobin GO:0019825 UA74_RS14415 007cfa0383c043f1f2d9bf2306561208 120 Gene3D G3DSA:1.10.490.10 2 118 7.4E-38 T 09-03-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UA74_RS20240 23bcf165669b6b1f38648e55c4a1f9e8 377 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 91 319 2.9E-29 T 09-03-2017 IPR018713 Domain of unknown function DUF2236 UA74_RS22120 ba998e24d9d2dc0916b0032aca793b78 137 Pfam PF00293 NUDIX domain 9 122 4.0E-15 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS22120 ba998e24d9d2dc0916b0032aca793b78 137 SUPERFAMILY SSF55811 6 130 1.76E-24 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS22120 ba998e24d9d2dc0916b0032aca793b78 137 Gene3D G3DSA:3.90.79.10 9 133 1.7E-24 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS22120 ba998e24d9d2dc0916b0032aca793b78 137 PRINTS PR00502 NUDIX hydrolase family signature 45 60 2.3E-6 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS22120 ba998e24d9d2dc0916b0032aca793b78 137 PRINTS PR00502 NUDIX hydrolase family signature 31 45 2.3E-6 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 PRINTS PR01466 Bacterial arginine deiminase signature 353 367 6.1E-38 T 09-03-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 PRINTS PR01466 Bacterial arginine deiminase signature 376 394 6.1E-38 T 09-03-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 PRINTS PR01466 Bacterial arginine deiminase signature 148 166 6.1E-38 T 09-03-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 PRINTS PR01466 Bacterial arginine deiminase signature 333 350 6.1E-38 T 09-03-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 PRINTS PR01466 Bacterial arginine deiminase signature 176 191 6.1E-38 T 09-03-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 Gene3D G3DSA:3.75.10.10 148 397 1.3E-117 T 09-03-2017 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 Gene3D G3DSA:3.75.10.10 3 65 1.3E-117 T 09-03-2017 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 SUPERFAMILY SSF55909 3 397 5.69E-114 T 09-03-2017 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 PIRSF PIRSF006356 2 397 1.0E-134 T 09-03-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 Pfam PF02274 Amidinotransferase 16 394 9.4E-87 T 09-03-2017 UA74_RS00490 f7949f796368e550e82e41e4e5f5169c 398 Hamap MF_00242 Arginine deiminase [arcA]. 1 397 41.137 T 09-03-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_RS26575 a5e080e376e62cd1c8de6f72f537eb60 555 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 235 241 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS26575 a5e080e376e62cd1c8de6f72f537eb60 555 Gene3D G3DSA:3.40.50.150 125 335 3.2E-56 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS26575 a5e080e376e62cd1c8de6f72f537eb60 555 SUPERFAMILY SSF53335 177 301 4.31E-14 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS26575 a5e080e376e62cd1c8de6f72f537eb60 555 Pfam PF01861 Protein of unknown function DUF43 132 304 4.4E-29 T 09-03-2017 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal UA74_RS18905 2cb4ec17e6f900e465b323b97556719c 140 Gene3D G3DSA:2.30.40.10 1 32 1.6E-5 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS11435 66947715f3e5adf9697ac6ac427f80d6 290 Pfam PF00296 Luciferase-like monooxygenase 20 245 8.9E-46 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS11435 66947715f3e5adf9697ac6ac427f80d6 290 SUPERFAMILY SSF51679 4 285 1.35E-57 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS11435 66947715f3e5adf9697ac6ac427f80d6 290 Gene3D G3DSA:3.20.20.30 1 252 2.1E-65 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS11435 66947715f3e5adf9697ac6ac427f80d6 290 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 10 232 1.3E-89 T 09-03-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c UA74_RS12060 5d953bbb1cda96e94d44b3cbd36c76d7 149 Pfam PF07681 DoxX 12 94 9.7E-20 T 09-03-2017 IPR032808 DoxX family UA74_RS17545 2e307a41fb596459d94f963c488e56fc 137 SUPERFAMILY SSF54593 6 133 4.83E-22 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS17545 2e307a41fb596459d94f963c488e56fc 137 Gene3D G3DSA:3.10.180.10 8 132 3.0E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS17545 2e307a41fb596459d94f963c488e56fc 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 129 5.4E-8 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 SMART SM00490 423 500 1.1E-12 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 Pfam PF13625 Helicase conserved C-terminal domain 6 133 1.3E-44 T 09-03-2017 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 SUPERFAMILY SSF52540 387 527 6.57E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 SUPERFAMILY SSF52540 284 354 6.57E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 1.8E-14 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 SMART SM00487 178 353 3.4E-22 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 356 378 2.4E-34 T 09-03-2017 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 456 474 2.4E-34 T 09-03-2017 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 475 500 2.4E-34 T 09-03-2017 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 291 311 2.4E-34 T 09-03-2017 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 191 213 2.4E-34 T 09-03-2017 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 540 3.9E-45 T 09-03-2017 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 SUPERFAMILY SSF52540 146 345 2.85E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 Gene3D G3DSA:3.40.50.300 180 344 3.7E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28665 6e84b01c992feed8b267039678c8f74e 553 Gene3D G3DSA:3.40.50.300 379 534 3.3E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20190 c092c3a743e1a29b5114ecc2ccc97f12 254 Gene3D G3DSA:1.10.357.10 26 253 1.6E-57 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS20190 c092c3a743e1a29b5114ecc2ccc97f12 254 SUPERFAMILY SSF46689 29 91 5.49E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20190 c092c3a743e1a29b5114ecc2ccc97f12 254 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 97 250 8.0E-18 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS20190 c092c3a743e1a29b5114ecc2ccc97f12 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 84 6.9E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS20190 c092c3a743e1a29b5114ecc2ccc97f12 254 SUPERFAMILY SSF48498 103 253 4.0E-28 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS28330 f411b856566bfee95f3d7d81a2687245 263 Gene3D G3DSA:1.10.260.40 2 49 1.9E-4 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28330 f411b856566bfee95f3d7d81a2687245 263 Pfam PF13560 Helix-turn-helix domain 1 52 3.1E-6 T 09-03-2017 UA74_RS27475 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 38 62 5.9E-9 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS27475 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 103 121 5.9E-9 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS27475 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 134 151 5.9E-9 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS27475 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 205 229 5.9E-9 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS27475 1a07934013e28912af7f74ca1463bb44 277 Gene3D G3DSA:3.20.20.100 6 273 2.2E-75 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS27475 1a07934013e28912af7f74ca1463bb44 277 SUPERFAMILY SSF51430 6 271 7.33E-72 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS27475 1a07934013e28912af7f74ca1463bb44 277 Pfam PF00248 Aldo/keto reductase family 8 271 4.9E-61 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS08495 6bfedad0204ba59845831f99b707e9ee 373 Gene3D G3DSA:3.40.50.2300 40 163 1.5E-24 T 09-03-2017 UA74_RS08495 6bfedad0204ba59845831f99b707e9ee 373 Gene3D G3DSA:3.40.50.2300 164 347 4.3E-41 T 09-03-2017 UA74_RS08495 6bfedad0204ba59845831f99b707e9ee 373 Pfam PF13407 Periplasmic binding protein domain 47 307 1.0E-56 T 09-03-2017 IPR025997 Periplasmic binding protein UA74_RS08495 6bfedad0204ba59845831f99b707e9ee 373 SUPERFAMILY SSF53822 44 347 2.51E-59 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS26415 83b1c8737cabaa0bd0e1f04f5a78df9f 121 Pfam PF02656 Domain of unknown function (DUF202) 22 85 2.1E-14 T 09-03-2017 IPR003807 Domain of unknown function DUF202 UA74_RS16160 7c4df442db61cd510c23ffa8d911c449 198 SUPERFAMILY SSF55073 44 195 6.59E-27 T 09-03-2017 IPR029787 Nucleotide cyclase UA74_RS16160 7c4df442db61cd510c23ffa8d911c449 198 SMART SM00267 29 196 3.1E-23 T 09-03-2017 IPR000160 GGDEF domain UA74_RS16160 7c4df442db61cd510c23ffa8d911c449 198 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 40 194 9.3E-25 T 09-03-2017 IPR000160 GGDEF domain UA74_RS16160 7c4df442db61cd510c23ffa8d911c449 198 Gene3D G3DSA:3.30.70.270 41 195 4.5E-32 T 09-03-2017 UA74_RS16160 7c4df442db61cd510c23ffa8d911c449 198 Pfam PF00990 Diguanylate cyclase, GGDEF domain 41 191 7.8E-25 T 09-03-2017 IPR000160 GGDEF domain UA74_RS13085 ae08057a51bad3f9666109893c807f19 234 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13085 ae08057a51bad3f9666109893c807f19 234 Gene3D G3DSA:3.40.50.300 11 228 8.4E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13085 ae08057a51bad3f9666109893c807f19 234 Pfam PF00005 ABC transporter 33 178 4.8E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13085 ae08057a51bad3f9666109893c807f19 234 SUPERFAMILY SSF52540 12 227 1.95E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13085 ae08057a51bad3f9666109893c807f19 234 SMART SM00382 41 225 5.9E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16355 f3041155cb498854599da5546e293934 80 Gene3D G3DSA:3.30.420.10 2 74 5.2E-16 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS16355 f3041155cb498854599da5546e293934 80 SUPERFAMILY SSF53098 2 73 1.15E-13 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS16355 f3041155cb498854599da5546e293934 80 Pfam PF00665 Integrase core domain 2 74 2.4E-10 T 09-03-2017 IPR001584 Integrase, catalytic core GO:0015074 UA74_RS00625 a2fee8df01481c0669842d9e281335d8 270 Gene3D G3DSA:3.40.50.1000 174 270 4.3E-52 T 09-03-2017 IPR023214 HAD-like domain UA74_RS00625 a2fee8df01481c0669842d9e281335d8 270 Gene3D G3DSA:3.40.50.1000 3 74 4.3E-52 T 09-03-2017 IPR023214 HAD-like domain UA74_RS00625 a2fee8df01481c0669842d9e281335d8 270 SUPERFAMILY SSF56784 3 270 2.51E-59 T 09-03-2017 IPR023214 HAD-like domain UA74_RS00625 a2fee8df01481c0669842d9e281335d8 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 266 6.5E-51 T 09-03-2017 IPR023214 HAD-like domain UA74_RS09800 5676e77bcdbe06ed104b28bc285971fb 275 Pfam PF05103 DivIVA protein 3 65 5.8E-13 T 09-03-2017 IPR007793 DivIVA family UA74_RS09800 5676e77bcdbe06ed104b28bc285971fb 275 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 6.1E-15 T 09-03-2017 IPR019933 DivIVA domain UA74_RS23685 7a016297af8da2cc7e303b6d9ffc8651 319 SUPERFAMILY SSF53335 92 293 4.54E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23685 7a016297af8da2cc7e303b6d9ffc8651 319 Gene3D G3DSA:3.40.50.150 92 290 1.1E-41 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23685 7a016297af8da2cc7e303b6d9ffc8651 319 Pfam PF02353 Mycolic acid cyclopropane synthetase 92 288 1.0E-38 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21145 cbeb891f0117b7183e8f238dd6cf2f8b 416 SUPERFAMILY SSF53850 16 413 5.69E-41 T 09-03-2017 UA74_RS21145 cbeb891f0117b7183e8f238dd6cf2f8b 416 Gene3D G3DSA:3.40.190.10 27 154 1.3E-13 T 09-03-2017 UA74_RS21145 cbeb891f0117b7183e8f238dd6cf2f8b 416 Gene3D G3DSA:3.40.190.10 155 343 2.6E-15 T 09-03-2017 UA74_RS21145 cbeb891f0117b7183e8f238dd6cf2f8b 416 Pfam PF13416 Bacterial extracellular solute-binding protein 41 344 9.5E-28 T 09-03-2017 UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 Pfam PF01037 Lrp/AsnC ligand binding domain 69 137 3.9E-13 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 Gene3D G3DSA:3.30.70.920 53 138 3.0E-14 T 09-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 SUPERFAMILY SSF54909 63 137 8.85E-12 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 Pfam PF13404 AsnC-type helix-turn-helix domain 1 41 8.6E-16 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 SMART SM00344 1 108 4.4E-18 T 09-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 SUPERFAMILY SSF46785 1 55 1.8E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 Gene3D G3DSA:1.10.10.10 2 48 6.5E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.4E-12 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.4E-12 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS10390 6c6c33a96ab3acc729b8cec3b294a95c 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.4E-12 T 09-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 UA74_RS01180 21dd525c5175b7cbc6e02805a4da6c99 157 Gene3D G3DSA:3.30.1330.40 7 156 4.0E-67 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS01180 21dd525c5175b7cbc6e02805a4da6c99 157 SUPERFAMILY SSF55298 8 156 3.46E-55 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS01180 21dd525c5175b7cbc6e02805a4da6c99 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 11 155 5.2E-30 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS10145 6bd8071d910488f3afee540ced57fa62 241 Gene3D G3DSA:3.40.50.300 9 227 1.0E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10145 6bd8071d910488f3afee540ced57fa62 241 Pfam PF02224 Cytidylate kinase 10 226 3.1E-63 T 09-03-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 UA74_RS10145 6bd8071d910488f3afee540ced57fa62 241 Hamap MF_00238 Cytidylate kinase [cmk]. 8 231 29.339 T 09-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 UA74_RS10145 6bd8071d910488f3afee540ced57fa62 241 SUPERFAMILY SSF52540 9 227 9.66E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10145 6bd8071d910488f3afee540ced57fa62 241 TIGRFAM TIGR00017 cmk: cytidylate kinase 9 220 8.3E-59 T 09-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 UA74_RS17900 907a8621ee81877f24849ed8ef5f78c2 270 SUPERFAMILY SSF161098 9 270 9.27E-64 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS17900 907a8621ee81877f24849ed8ef5f78c2 270 Gene3D G3DSA:1.10.3720.10 9 257 7.8E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS17900 907a8621ee81877f24849ed8ef5f78c2 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 255 5.5E-20 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 SUPERFAMILY SSF51735 3 168 4.7E-61 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 Gene3D G3DSA:3.40.50.720 2 160 6.9E-73 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 317 5.6E-67 T 09-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 5.2E-41 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 5.2E-41 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 5.2E-41 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 5.2E-41 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 5.2E-41 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 SUPERFAMILY SSF55347 152 318 5.66E-71 T 09-03-2017 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 329 1.1E-134 T 09-03-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 SMART SM00846 3 152 7.9E-90 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 8.0E-57 T 09-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 PIRSF PIRSF000149 1 338 4.6E-131 T 09-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_RS12440 0f3f0b5a8603c38fbf35eaea01a398b1 339 Gene3D G3DSA:3.30.360.10 161 319 3.2E-75 T 09-03-2017 UA74_RS26330 7f035443552759a62d6fe8c6180b73dd 260 Gene3D G3DSA:3.40.50.1820 7 249 1.1E-40 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26330 7f035443552759a62d6fe8c6180b73dd 260 SUPERFAMILY SSF53474 6 248 1.14E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26330 7f035443552759a62d6fe8c6180b73dd 260 Pfam PF00561 alpha/beta hydrolase fold 14 134 3.9E-16 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS17030 fdf66e0fdc451db69f938ec5daecaad4 333 Gene3D G3DSA:3.10.310.10 155 320 7.7E-57 T 09-03-2017 UA74_RS17030 fdf66e0fdc451db69f938ec5daecaad4 333 Pfam PF05544 Proline racemase 10 331 1.9E-121 T 09-03-2017 IPR008794 Proline racemase family UA74_RS17030 fdf66e0fdc451db69f938ec5daecaad4 333 Gene3D G3DSA:3.10.310.10 5 154 4.0E-64 T 09-03-2017 UA74_RS17030 fdf66e0fdc451db69f938ec5daecaad4 333 SUPERFAMILY SSF54506 2 331 6.73E-110 T 09-03-2017 UA74_RS17030 fdf66e0fdc451db69f938ec5daecaad4 333 PIRSF PIRSF029792 1 333 8.7E-122 T 09-03-2017 IPR008794 Proline racemase family UA74_RS17225 d77af151171f05b619564440664dedb6 277 SMART SM00382 27 212 5.5E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS17225 d77af151171f05b619564440664dedb6 277 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS17225 d77af151171f05b619564440664dedb6 277 SUPERFAMILY SSF52540 3 224 1.67E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17225 d77af151171f05b619564440664dedb6 277 Gene3D G3DSA:3.40.50.300 3 227 5.0E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17225 d77af151171f05b619564440664dedb6 277 Pfam PF00005 ABC transporter 20 167 4.6E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 23 460 7.1E-137 T 09-03-2017 IPR004452 4Fe-4S binding protein GO:0019516 UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 Pfam PF13183 4Fe-4S dicluster domain 314 384 4.7E-9 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 Gene3D G3DSA:1.10.1060.10 296 404 1.2E-12 T 09-03-2017 UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 SUPERFAMILY SSF54862 295 399 2.85E-15 T 09-03-2017 UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 SUPERFAMILY SSF100950 69 93 7.11E-35 T 09-03-2017 UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 SUPERFAMILY SSF100950 139 299 7.11E-35 T 09-03-2017 UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 317 328 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 Gene3D G3DSA:3.40.50.10420 70 132 1.2E-41 T 09-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 Gene3D G3DSA:3.40.50.10420 196 295 1.2E-41 T 09-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 74 297 3.0E-47 T 09-03-2017 IPR003741 LUD domain UA74_RS20715 0f7ce87853c8c2fa255604d7d913f9c7 476 Pfam PF11870 Domain of unknown function (DUF3390) 400 473 1.0E-6 T 09-03-2017 IPR024569 4Fe-4S binding protein, C-terminal UA74_RS24340 d256dbeb0518c680357f7bbd8d22d487 156 Pfam PF01814 Hemerythrin HHE cation binding domain 14 138 8.0E-18 T 09-03-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 UA74_RS24340 d256dbeb0518c680357f7bbd8d22d487 156 Gene3D G3DSA:1.20.120.520 12 140 7.2E-26 T 09-03-2017 UA74_RS20365 8b4b0a1c03e34f75f6704bd407e651ec 117 Pfam PF05331 Protein of unknown function (DUF742) 6 115 6.8E-36 T 09-03-2017 IPR007995 Protein of unknown function DUF742 UA74_RS20365 8b4b0a1c03e34f75f6704bd407e651ec 117 Gene3D G3DSA:1.10.10.10 43 92 3.7E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04725 f12bea9a685fd6758b49dd21da7d26c1 268 Pfam PF12705 PD-(D/E)XK nuclease superfamily 8 250 2.8E-30 T 09-03-2017 UA74_RS23590 559b35741476053fd27ae6613ba95453 181 SUPERFAMILY SSF52317 1 169 3.73E-44 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS23590 559b35741476053fd27ae6613ba95453 181 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 166 3.7E-47 T 09-03-2017 IPR006286 Peptidase C56, PfpI UA74_RS23590 559b35741476053fd27ae6613ba95453 181 Gene3D G3DSA:3.40.50.880 1 172 5.4E-53 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS23590 559b35741476053fd27ae6613ba95453 181 Pfam PF01965 DJ-1/PfpI family 1 167 1.3E-52 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS09450 4b43058cdc8e6685d136f01ce31f5b39 114 SUPERFAMILY SSF50022 7 113 1.23E-34 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS09450 4b43058cdc8e6685d136f01ce31f5b39 114 Pfam PF13806 Rieske-like [2Fe-2S] domain 8 111 5.7E-36 T 09-03-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 UA74_RS09450 4b43058cdc8e6685d136f01ce31f5b39 114 Gene3D G3DSA:2.102.10.10 7 112 1.9E-40 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS09450 4b43058cdc8e6685d136f01ce31f5b39 114 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 8 111 2.0E-34 T 09-03-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 UA74_RS05050 b1798ac90ade680c2e95ff99e2b16ba0 28 Pfam PF04149 Domain of unknown function (DUF397) 3 28 5.2E-5 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS14495 a939ae9243ce40b4ae117379da23d7f9 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS14495 a939ae9243ce40b4ae117379da23d7f9 497 Pfam PF00171 Aldehyde dehydrogenase family 37 493 1.3E-166 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS14495 a939ae9243ce40b4ae117379da23d7f9 497 Gene3D G3DSA:3.40.605.10 24 281 3.1E-99 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS14495 a939ae9243ce40b4ae117379da23d7f9 497 Gene3D G3DSA:3.40.309.10 282 468 2.7E-64 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS14495 a939ae9243ce40b4ae117379da23d7f9 497 SUPERFAMILY SSF53720 24 496 1.7E-165 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS28995 297a324f9a48190d34144b404f59d2c7 345 Gene3D G3DSA:3.40.50.720 1 189 1.6E-28 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28995 297a324f9a48190d34144b404f59d2c7 345 Gene3D G3DSA:3.90.25.10 190 307 1.4E-13 T 09-03-2017 UA74_RS28995 297a324f9a48190d34144b404f59d2c7 345 SUPERFAMILY SSF51735 1 317 7.08E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28995 297a324f9a48190d34144b404f59d2c7 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 235 6.5E-41 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 SUPERFAMILY SSF103473 13 223 6.8E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 SUPERFAMILY SSF103473 283 446 6.8E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 153 3.1E-13 T 09-03-2017 UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 163 187 3.1E-13 T 09-03-2017 UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 42 66 3.1E-13 T 09-03-2017 UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 Gene3D G3DSA:1.20.1250.20 347 445 2.2E-6 T 09-03-2017 UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 Pfam PF07690 Major Facilitator Superfamily 44 393 3.4E-40 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS15100 737d4286981ed325e27b6bf97091bf48 451 Gene3D G3DSA:1.20.1250.20 35 220 2.1E-31 T 09-03-2017 UA74_RS28420 748c57d88506363f871deff65b5cf16b 459 PIRSF PIRSF006060 8 448 3.3E-70 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 UA74_RS28420 748c57d88506363f871deff65b5cf16b 459 Pfam PF13520 Amino acid permease 30 411 3.3E-38 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 UA74_RS18255 98e616c9db92853e00f75e3043186945 497 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 32 227 1.1E-19 T 09-03-2017 IPR001099 Chalcone/stilbene synthase, N-terminal UA74_RS18255 98e616c9db92853e00f75e3043186945 497 Gene3D G3DSA:3.40.47.10 354 497 5.9E-36 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18255 98e616c9db92853e00f75e3043186945 497 Gene3D G3DSA:3.40.47.10 24 231 3.7E-55 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18255 98e616c9db92853e00f75e3043186945 497 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 359 496 2.2E-15 T 09-03-2017 IPR012328 Chalcone/stilbene synthase, C-terminal UA74_RS18255 98e616c9db92853e00f75e3043186945 497 SUPERFAMILY SSF53901 354 497 1.54E-37 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS18255 98e616c9db92853e00f75e3043186945 497 SUPERFAMILY SSF53901 27 231 5.77E-50 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS12140 62d2633a70b726d021395ce8874982f7 409 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 46 398 1.7E-35 T 09-03-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like UA74_RS12140 62d2633a70b726d021395ce8874982f7 409 Pfam PF02618 YceG-like family 82 399 4.0E-54 T 09-03-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like UA74_RS23500 3327e126df192a4bec3a056145d4d3d4 234 Gene3D G3DSA:3.60.40.10 12 166 6.2E-9 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS23500 3327e126df192a4bec3a056145d4d3d4 234 SUPERFAMILY SSF81606 15 233 1.57E-13 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS23500 3327e126df192a4bec3a056145d4d3d4 234 Pfam PF13672 Protein phosphatase 2C 17 180 2.0E-8 T 09-03-2017 UA74_RS15615 98f0b9e9b03e13bba81f04d123425abb 278 PIRSF PIRSF000103 1 278 3.6E-32 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_RS15615 98f0b9e9b03e13bba81f04d123425abb 278 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 151 3.2E-14 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS15615 98f0b9e9b03e13bba81f04d123425abb 278 SUPERFAMILY SSF51735 1 153 6.05E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS15615 98f0b9e9b03e13bba81f04d123425abb 278 Gene3D G3DSA:3.40.50.720 2 154 5.1E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10550 66a537e4b0e4dfce1f8492539312ab8d 134 SUPERFAMILY SSF46785 5 97 1.41E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10550 66a537e4b0e4dfce1f8492539312ab8d 134 SMART SM00418 5 84 2.3E-21 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS10550 66a537e4b0e4dfce1f8492539312ab8d 134 Gene3D G3DSA:1.10.10.10 5 102 1.6E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10550 66a537e4b0e4dfce1f8492539312ab8d 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.7E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS10550 66a537e4b0e4dfce1f8492539312ab8d 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.7E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS10550 66a537e4b0e4dfce1f8492539312ab8d 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 2.7E-9 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS10550 66a537e4b0e4dfce1f8492539312ab8d 134 Pfam PF12840 Helix-turn-helix domain 6 64 5.7E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13345 f42dfc8a5c27d952d0a33dd550877dee 603 Gene3D G3DSA:3.40.50.300 415 597 4.8E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13345 f42dfc8a5c27d952d0a33dd550877dee 603 Gene3D G3DSA:3.40.50.300 339 375 4.8E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13345 f42dfc8a5c27d952d0a33dd550877dee 603 Gene3D G3DSA:1.20.1560.10 7 319 6.5E-37 T 09-03-2017 UA74_RS13345 f42dfc8a5c27d952d0a33dd550877dee 603 Pfam PF00005 ABC transporter 477 527 2.1E-6 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13345 f42dfc8a5c27d952d0a33dd550877dee 603 SUPERFAMILY SSF90123 7 319 8.11E-45 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13345 f42dfc8a5c27d952d0a33dd550877dee 603 SUPERFAMILY SSF52540 414 599 3.25E-36 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13345 f42dfc8a5c27d952d0a33dd550877dee 603 Pfam PF00664 ABC transporter transmembrane region 28 283 6.1E-11 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS24370 9339c54b0e4cf08a86dbcb31b3a42cfe 173 Gene3D G3DSA:1.10.10.10 7 85 2.0E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24370 9339c54b0e4cf08a86dbcb31b3a42cfe 173 Pfam PF03551 Transcriptional regulator PadR-like family 10 83 3.8E-9 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS24370 9339c54b0e4cf08a86dbcb31b3a42cfe 173 SUPERFAMILY SSF46785 7 167 1.03E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05745 1f43d0634d073d34bf9931bea3fe3797 452 Gene3D G3DSA:3.20.20.80 9 285 1.3E-21 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS05745 1f43d0634d073d34bf9931bea3fe3797 452 SUPERFAMILY SSF51445 8 360 1.64E-26 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS05255 08885d28cf00aead37ff81e0a04eef0e 279 SUPERFAMILY SSF53335 24 226 3.05E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05255 08885d28cf00aead37ff81e0a04eef0e 279 Gene3D G3DSA:3.40.50.150 27 258 6.0E-33 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05255 08885d28cf00aead37ff81e0a04eef0e 279 Pfam PF08241 Methyltransferase domain 53 150 1.0E-17 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS07290 4682a672374e3c541fb876f437374ff7 249 SUPERFAMILY SSF53474 14 220 1.26E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07290 4682a672374e3c541fb876f437374ff7 249 Gene3D G3DSA:3.40.50.1820 18 221 1.1E-31 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26300 dbd0d7dbb8e528dd3e0b1be2e6f842de 345 Gene3D G3DSA:3.20.20.210 92 334 1.1E-11 T 09-03-2017 UA74_RS26300 dbd0d7dbb8e528dd3e0b1be2e6f842de 345 SUPERFAMILY SSF51726 63 338 2.62E-27 T 09-03-2017 UA74_RS26300 dbd0d7dbb8e528dd3e0b1be2e6f842de 345 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 10 334 1.7E-17 T 09-03-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS16745 fa5cc3e812844b76212f0c9e0f3846f2 139 Gene3D G3DSA:1.10.10.10 12 121 8.1E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16745 fa5cc3e812844b76212f0c9e0f3846f2 139 Pfam PF12802 MarR family 30 82 9.6E-11 T 09-03-2017 UA74_RS16745 fa5cc3e812844b76212f0c9e0f3846f2 139 SUPERFAMILY SSF46785 8 120 3.12E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16745 fa5cc3e812844b76212f0c9e0f3846f2 139 SMART SM00347 25 124 0.0022 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS01680 083e52de6b8431e2581d4d9938e9214d 65 Pfam PF12728 Helix-turn-helix domain 10 55 5.0E-11 T 09-03-2017 UA74_RS01680 083e52de6b8431e2581d4d9938e9214d 65 Gene3D G3DSA:1.10.10.10 10 58 1.8E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01680 083e52de6b8431e2581d4d9938e9214d 65 SUPERFAMILY SSF46955 9 57 5.37E-9 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS25715 0d674236a0e790bb49840b6b970e5092 100 Pfam PF00708 Acylphosphatase 14 89 8.4E-21 T 09-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UA74_RS25715 0d674236a0e790bb49840b6b970e5092 100 ProSitePatterns PS00150 Acylphosphatase signature 1. 19 29 - T 09-03-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UA74_RS25715 0d674236a0e790bb49840b6b970e5092 100 SUPERFAMILY SSF54975 11 97 4.8E-23 T 09-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UA74_RS25715 0d674236a0e790bb49840b6b970e5092 100 Gene3D G3DSA:3.30.70.100 13 97 5.3E-24 T 09-03-2017 UA74_RS22145 ba639bde2c36be66779f245b65c6b008 325 SUPERFAMILY SSF51430 8 308 7.07E-101 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS22145 ba639bde2c36be66779f245b65c6b008 325 Pfam PF00248 Aldo/keto reductase family 13 307 4.8E-77 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS22145 ba639bde2c36be66779f245b65c6b008 325 Gene3D G3DSA:3.20.20.100 8 313 1.1E-110 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS22145 ba639bde2c36be66779f245b65c6b008 325 PRINTS PR00069 Aldo-keto reductase signature 241 265 1.0E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS22145 ba639bde2c36be66779f245b65c6b008 325 PRINTS PR00069 Aldo-keto reductase signature 42 66 1.0E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS22145 ba639bde2c36be66779f245b65c6b008 325 PRINTS PR00069 Aldo-keto reductase signature 108 126 1.0E-5 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 305 76.79 T 09-03-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 Gene3D G3DSA:3.40.50.1370 2 138 3.3E-52 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 141 1.1E-47 T 09-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 Gene3D G3DSA:3.40.50.1370 139 291 8.0E-60 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 302 3.0E-53 T 09-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 SUPERFAMILY SSF53671 2 305 2.23E-98 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 5.3E-27 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 5.3E-27 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 5.3E-27 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 5.3E-27 T 09-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 304 1.1E-115 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 4.5E-30 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 4.5E-30 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 4.5E-30 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 4.5E-30 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS21675 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 4.5E-30 T 09-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_RS00280 d444f7ce27792d1701379b6e68f3ea03 131 SUPERFAMILY SSF46955 5 119 3.33E-30 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS00280 d444f7ce27792d1701379b6e68f3ea03 131 Gene3D G3DSA:1.10.1660.10 5 118 6.6E-32 T 09-03-2017 UA74_RS00280 d444f7ce27792d1701379b6e68f3ea03 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 1.3E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS00280 d444f7ce27792d1701379b6e68f3ea03 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 1.3E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS00280 d444f7ce27792d1701379b6e68f3ea03 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 1.3E-5 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS00280 d444f7ce27792d1701379b6e68f3ea03 131 Pfam PF13411 MerR HTH family regulatory protein 5 70 7.2E-16 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS00280 d444f7ce27792d1701379b6e68f3ea03 131 SMART SM00422 5 74 5.9E-18 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS21025 fbf3104067bd1529028d5bef42a8df77 305 Gene3D G3DSA:3.60.10.10 5 280 5.4E-9 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS21025 fbf3104067bd1529028d5bef42a8df77 305 SUPERFAMILY SSF56219 4 282 2.36E-18 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS21025 fbf3104067bd1529028d5bef42a8df77 305 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 27 275 6.0E-15 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS09540 5c270bf223f6623dbc2d938427663979 69 TIGRFAM TIGR03898 lanti_MRSA_kill: type 2 lantibiotic, mersacidin/lichenicidin family 2 37 6.8E-7 T 09-03-2017 IPR027635 Type 2 lantibiotic, leader peptide domain GO:0042742 UA74_RS06710 b5eb6eccb18471eac27ab093fcfc379f 271 SUPERFAMILY SSF53474 12 222 2.13E-39 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06710 b5eb6eccb18471eac27ab093fcfc379f 271 Gene3D G3DSA:3.40.50.1820 11 226 4.2E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06710 b5eb6eccb18471eac27ab093fcfc379f 271 Pfam PF01764 Lipase (class 3) 75 208 2.4E-30 T 09-03-2017 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 UA74_RS09295 176ea1a333257309e6face9b06806ff2 136 SUPERFAMILY SSF111038 4 132 3.14E-31 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 UA74_RS09295 176ea1a333257309e6face9b06806ff2 136 Pfam PF01894 Uncharacterised protein family UPF0047 19 130 1.3E-21 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 UA74_RS09295 176ea1a333257309e6face9b06806ff2 136 Gene3D G3DSA:2.60.120.460 3 132 9.1E-29 T 09-03-2017 IPR001602 Uncharacterised protein family UPF0047 UA74_RS25455 4336e6db97a87833341042b8b2a7a5d9 418 Pfam PF09661 Protein of unknown function (DUF2398) 34 384 2.8E-93 T 09-03-2017 IPR013494 Conserved hypothetical protein CHP02678 UA74_RS25455 4336e6db97a87833341042b8b2a7a5d9 418 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 34 382 9.5E-39 T 09-03-2017 IPR013494 Conserved hypothetical protein CHP02678 UA74_RS16535 cf58a137dc170fe19b8f7002764fba4a 304 SUPERFAMILY SSF53448 8 100 1.46E-7 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS16535 cf58a137dc170fe19b8f7002764fba4a 304 Pfam PF13704 Glycosyl transferase family 2 10 101 1.1E-16 T 09-03-2017 UA74_RS16535 cf58a137dc170fe19b8f7002764fba4a 304 Gene3D G3DSA:3.90.550.10 31 99 1.3E-4 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS24755 08fda7561f2615e90751fc5bdb9a6700 259 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 33 138 1.4E-9 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_RS24755 08fda7561f2615e90751fc5bdb9a6700 259 Pfam PF07398 MDMPI C-terminal domain 152 248 1.2E-8 T 09-03-2017 IPR010872 MDMPI C-terminal UA74_RS02520 04a9521c8a2f7c494d77dae1f67323a3 324 SUPERFAMILY SSF53474 1 153 1.11E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02520 04a9521c8a2f7c494d77dae1f67323a3 324 SUPERFAMILY SSF53474 195 274 1.11E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02520 04a9521c8a2f7c494d77dae1f67323a3 324 Pfam PF12146 Serine aminopeptidase, S33 45 136 1.3E-9 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 UA74_RS02520 04a9521c8a2f7c494d77dae1f67323a3 324 Gene3D G3DSA:3.40.50.1820 230 258 2.0E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS02520 04a9521c8a2f7c494d77dae1f67323a3 324 Gene3D G3DSA:3.40.50.1820 1 154 2.0E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05840 127e94e865d6762d326ddfc3fd82d650 181 Gene3D G3DSA:3.90.470.20 61 168 2.5E-12 T 09-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 UA74_RS14750 c99490eeb8efeffc479a4ce38dfd730e 185 Gene3D G3DSA:1.10.3300.10 17 179 1.3E-29 T 09-03-2017 IPR023286 ABATE domain UA74_RS14750 c99490eeb8efeffc479a4ce38dfd730e 185 Pfam PF11706 CGNR zinc finger 136 179 3.0E-17 T 09-03-2017 IPR021005 Zinc finger, CGNR UA74_RS14750 c99490eeb8efeffc479a4ce38dfd730e 185 SUPERFAMILY SSF160904 7 178 1.26E-31 T 09-03-2017 UA74_RS12900 39dd427d6c173c50c78af8b650a58843 344 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 15 331 1.7E-81 T 09-03-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 UA74_RS12900 39dd427d6c173c50c78af8b650a58843 344 SUPERFAMILY SSF51556 10 334 3.68E-73 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS12900 39dd427d6c173c50c78af8b650a58843 344 Pfam PF00962 Adenosine/AMP deaminase 15 328 6.7E-70 T 09-03-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 UA74_RS12900 39dd427d6c173c50c78af8b650a58843 344 Gene3D G3DSA:3.20.20.140 12 332 4.3E-88 T 09-03-2017 UA74_RS06400 cdb3545627a851d2af6c79acde0f098d 198 SUPERFAMILY SSF46785 68 197 2.14E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06400 cdb3545627a851d2af6c79acde0f098d 198 Gene3D G3DSA:1.10.10.10 68 198 7.1E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26190 87d6cdd0af9bd161e4ef613f2b400013 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 269 3.5E-43 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS26190 87d6cdd0af9bd161e4ef613f2b400013 304 SUPERFAMILY SSF52283 34 118 3.4E-5 T 09-03-2017 UA74_RS26190 87d6cdd0af9bd161e4ef613f2b400013 304 SUPERFAMILY SSF51735 96 270 5.05E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26190 87d6cdd0af9bd161e4ef613f2b400013 304 Gene3D G3DSA:3.40.50.720 96 270 4.0E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20855 9c0b2f0f0ae3ef4a55be14a55533a198 146 Pfam PF06841 T4-like virus tail tube protein gp19 11 143 2.5E-26 T 09-03-2017 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 UA74_RS20855 9c0b2f0f0ae3ef4a55be14a55533a198 146 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 6 146 1.3E-25 T 09-03-2017 IPR011747 Conserved hypothetical protein CHP02241 UA74_RS06785 c2b927b1d030b14f456cf18137198fad 179 Gene3D G3DSA:3.40.630.30 14 163 1.7E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS06785 c2b927b1d030b14f456cf18137198fad 179 Pfam PF00583 Acetyltransferase (GNAT) family 72 157 1.2E-6 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS06785 c2b927b1d030b14f456cf18137198fad 179 SUPERFAMILY SSF55729 13 165 2.79E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS13485 c6eb0cd2c8f40aa0d4bbc881d5bcc1e6 163 SUPERFAMILY SSF109854 6 158 6.78E-35 T 09-03-2017 UA74_RS13485 c6eb0cd2c8f40aa0d4bbc881d5bcc1e6 163 Gene3D G3DSA:1.20.120.450 7 163 2.3E-36 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS13485 c6eb0cd2c8f40aa0d4bbc881d5bcc1e6 163 Pfam PF04978 Protein of unknown function (DUF664) 22 159 1.0E-36 T 09-03-2017 IPR007061 Protein of unknown function DUF664 UA74_RS16835 84157c665f7f4973cd5b48aca81cc6d9 280 Pfam PF07920 Protein of unknown function (DUF1684) 136 273 9.4E-24 T 09-03-2017 IPR012467 Protein of unknown function DUF1684 UA74_RS14860 085c86a9eec0e0580ae397a91eef0205 325 Pfam PF00589 Phage integrase family 139 298 3.1E-19 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS14860 085c86a9eec0e0580ae397a91eef0205 325 SUPERFAMILY SSF56349 5 307 3.53E-35 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS14860 085c86a9eec0e0580ae397a91eef0205 325 Gene3D G3DSA:1.10.150.130 17 103 3.3E-11 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS14860 085c86a9eec0e0580ae397a91eef0205 325 Gene3D G3DSA:1.10.443.10 138 306 4.0E-33 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS03735 08ea6140f64e1d7604564253deb6d95e 125 Gene3D G3DSA:1.25.40.10 4 116 4.6E-18 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03735 08ea6140f64e1d7604564253deb6d95e 125 Pfam PF13432 Tetratricopeptide repeat 45 105 1.8E-8 T 09-03-2017 UA74_RS03735 08ea6140f64e1d7604564253deb6d95e 125 SUPERFAMILY SSF48452 8 106 7.59E-16 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS03735 08ea6140f64e1d7604564253deb6d95e 125 SMART SM00028 40 73 0.13 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS03735 08ea6140f64e1d7604564253deb6d95e 125 SMART SM00028 74 107 21.0 T 09-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_RS10150 0c12290fddfb1ac6d7292089f447a082 240 SUPERFAMILY SSF69593 35 227 1.96E-35 T 09-03-2017 UA74_RS10150 0c12290fddfb1ac6d7292089f447a082 240 Pfam PF01553 Acyltransferase 45 167 1.2E-21 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS10150 0c12290fddfb1ac6d7292089f447a082 240 Gene3D G3DSA:3.40.1130.10 39 171 6.0E-16 T 09-03-2017 UA74_RS10150 0c12290fddfb1ac6d7292089f447a082 240 SMART SM00563 60 170 5.4E-31 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS20060 c6aa7cdd48549c330fa327c958541635 143 Gene3D G3DSA:3.10.180.10 7 142 8.4E-7 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS20060 c6aa7cdd48549c330fa327c958541635 143 SUPERFAMILY SSF54593 5 142 4.95E-10 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 368 377 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 Gene3D G3DSA:1.10.630.10 32 425 6.7E-117 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 Pfam PF00067 Cytochrome P450 55 289 1.9E-12 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 Pfam PF00067 Cytochrome P450 300 387 1.3E-12 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 158 174 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 375 386 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 345 360 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 213 235 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 366 375 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 299 310 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 111 122 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 175 190 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00359 B-class P450 signature 317 344 1.3E-50 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 SUPERFAMILY SSF48264 36 424 1.7E-87 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00385 P450 superfamily signature 299 310 2.6E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00385 P450 superfamily signature 264 281 2.6E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00385 P450 superfamily signature 366 375 2.6E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS06960 3c59fd74656e1e1e240d8d2f9db87296 425 PRINTS PR00385 P450 superfamily signature 375 386 2.6E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS19445 2f6b9133f0ecd6dd47299c0403b32977 352 Gene3D G3DSA:3.40.50.1820 81 322 8.6E-45 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19445 2f6b9133f0ecd6dd47299c0403b32977 352 Pfam PF00756 Putative esterase 81 317 4.1E-27 T 09-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 UA74_RS19445 2f6b9133f0ecd6dd47299c0403b32977 352 SUPERFAMILY SSF53474 76 216 1.28E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19445 2f6b9133f0ecd6dd47299c0403b32977 352 SUPERFAMILY SSF53474 246 326 1.28E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14265 361a428b289af976a658b9fdcd02698d 150 Pfam PF00583 Acetyltransferase (GNAT) family 52 133 2.4E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS14265 361a428b289af976a658b9fdcd02698d 150 Gene3D G3DSA:3.40.630.30 3 138 2.0E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS14265 361a428b289af976a658b9fdcd02698d 150 SUPERFAMILY SSF55729 1 140 1.47E-20 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS06035 2742f79084947ce6aa9feac37dcd52f0 392 Pfam PF16483 Beta-1,3-glucanase 46 389 1.1E-96 T 09-03-2017 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 UA74_RS20435 594091299517a38cb41d41f8f3ad4d94 320 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 119 225 8.4E-11 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS20435 594091299517a38cb41d41f8f3ad4d94 320 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 219 1.9E-13 T 09-03-2017 IPR023214 HAD-like domain UA74_RS20435 594091299517a38cb41d41f8f3ad4d94 320 Gene3D G3DSA:3.40.50.1000 129 252 8.7E-32 T 09-03-2017 IPR023214 HAD-like domain UA74_RS20435 594091299517a38cb41d41f8f3ad4d94 320 Gene3D G3DSA:3.40.50.1000 7 22 8.7E-32 T 09-03-2017 IPR023214 HAD-like domain UA74_RS20435 594091299517a38cb41d41f8f3ad4d94 320 Gene3D G3DSA:1.10.150.240 23 121 3.2E-4 T 09-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 UA74_RS20435 594091299517a38cb41d41f8f3ad4d94 320 SUPERFAMILY SSF56784 9 252 5.51E-39 T 09-03-2017 IPR023214 HAD-like domain UA74_RS25055 e204f5452be263d32b33f0a25b3eebce 203 Gene3D G3DSA:1.20.120.80 22 202 4.9E-55 T 09-03-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS25055 e204f5452be263d32b33f0a25b3eebce 203 Pfam PF00510 Cytochrome c oxidase subunit III 22 201 3.4E-25 T 09-03-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS25055 e204f5452be263d32b33f0a25b3eebce 203 SUPERFAMILY SSF81452 13 201 2.22E-58 T 09-03-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS08885 0041cdc7b617b416f1eab866c6e53539 181 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 11 168 2.0E-57 T 09-03-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 UA74_RS08885 0041cdc7b617b416f1eab866c6e53539 181 SUPERFAMILY SSF52540 8 171 2.38E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08885 0041cdc7b617b416f1eab866c6e53539 181 Gene3D G3DSA:3.40.50.300 5 171 1.3E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08885 0041cdc7b617b416f1eab866c6e53539 181 Pfam PF01202 Shikimate kinase 17 130 2.3E-10 T 09-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_RS01440 4ec1b4aa47318faa96a0de1aee75b382 591 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 334 401 3.8E-8 T 09-03-2017 IPR018905 Alpha-galactosidase, NEW3 domain UA74_RS01440 4ec1b4aa47318faa96a0de1aee75b382 591 SUPERFAMILY SSF49785 435 587 3.53E-37 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS01440 4ec1b4aa47318faa96a0de1aee75b382 591 SMART SM00776 432 589 7.1E-50 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module UA74_RS01440 4ec1b4aa47318faa96a0de1aee75b382 591 Gene3D G3DSA:3.60.21.10 49 283 1.8E-22 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS01440 4ec1b4aa47318faa96a0de1aee75b382 591 SUPERFAMILY SSF56300 39 306 3.48E-31 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS01440 4ec1b4aa47318faa96a0de1aee75b382 591 Pfam PF08305 NPCBM/NEW2 domain 435 587 1.2E-40 T 09-03-2017 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module UA74_RS01440 4ec1b4aa47318faa96a0de1aee75b382 591 Pfam PF00149 Calcineurin-like phosphoesterase 38 250 1.8E-14 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS21845 3feb9687f890ecd102948ae9b9aeff74 282 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 98 1.4E-10 T 09-03-2017 IPR022536 ESX-1 secretion-associated protein EspC UA74_RS28800 475e13a6ce058ad965962cf8dd258666 170 SUPERFAMILY SSF46785 7 137 2.33E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28800 475e13a6ce058ad965962cf8dd258666 170 Gene3D G3DSA:1.10.10.10 7 137 4.8E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28900 bbcaebc82366dc1e8b8b5ef65ce3340c 207 SUPERFAMILY SSF48150 21 198 6.5E-66 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS28900 bbcaebc82366dc1e8b8b5ef65ce3340c 207 Gene3D G3DSA:1.10.340.30 21 198 3.7E-71 T 09-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_RS28900 bbcaebc82366dc1e8b8b5ef65ce3340c 207 Pfam PF03352 Methyladenine glycosylase 25 195 3.5E-65 T 09-03-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 UA74_RS05600 4598e77001f5231436dcdd0ce66652db 141 Pfam PF12802 MarR family 31 82 3.0E-12 T 09-03-2017 UA74_RS05600 4598e77001f5231436dcdd0ce66652db 141 Gene3D G3DSA:1.10.10.10 13 129 5.4E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05600 4598e77001f5231436dcdd0ce66652db 141 SUPERFAMILY SSF46785 29 129 9.69E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05600 4598e77001f5231436dcdd0ce66652db 141 SMART SM00347 15 127 5.6E-4 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS29015 f9108bc4260047e42baa9e23819f20f2 502 Pfam PF13727 CoA-binding domain 104 234 2.9E-7 T 09-03-2017 UA74_RS29015 f9108bc4260047e42baa9e23819f20f2 502 Pfam PF02397 Bacterial sugar transferase 309 496 5.2E-58 T 09-03-2017 IPR003362 Bacterial sugar transferase UA74_RS29015 f9108bc4260047e42baa9e23819f20f2 502 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 48 502 4.6E-123 T 09-03-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase UA74_RS00225 81dbb3917c576e17fc06ec4a5518cda6 248 Pfam PF07987 Domain of unkown function (DUF1775) 31 174 4.8E-39 T 09-03-2017 IPR012533 GLE1, N-terminal, bacteria UA74_RS18895 2bef0bc086c27d12e8c99ea5abd16fb9 205 SUPERFAMILY SSF46785 4 173 1.51E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18895 2bef0bc086c27d12e8c99ea5abd16fb9 205 Pfam PF03551 Transcriptional regulator PadR-like family 8 80 3.4E-8 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS18895 2bef0bc086c27d12e8c99ea5abd16fb9 205 Gene3D G3DSA:1.10.10.10 4 93 3.7E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09610 a0204a2ad86625ea21d579a3f0eea61a 149 Gene3D G3DSA:3.90.950.20 2 145 3.8E-49 T 09-03-2017 IPR008136 CinA, C-terminal UA74_RS09610 a0204a2ad86625ea21d579a3f0eea61a 149 Pfam PF02464 Competence-damaged protein 2 143 1.2E-42 T 09-03-2017 IPR008136 CinA, C-terminal UA74_RS09610 a0204a2ad86625ea21d579a3f0eea61a 149 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 2 141 3.3E-32 T 09-03-2017 IPR008136 CinA, C-terminal UA74_RS09610 a0204a2ad86625ea21d579a3f0eea61a 149 SUPERFAMILY SSF142433 2 144 9.15E-41 T 09-03-2017 IPR008136 CinA, C-terminal UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 Gene3D G3DSA:1.20.1250.20 26 219 9.7E-32 T 09-03-2017 UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 Gene3D G3DSA:1.20.1250.20 292 488 3.7E-12 T 09-03-2017 UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 157 181 7.0E-8 T 09-03-2017 UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 127 147 7.0E-8 T 09-03-2017 UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 36 60 7.0E-8 T 09-03-2017 UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 SUPERFAMILY SSF103473 28 220 7.72E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 SUPERFAMILY SSF103473 274 489 7.72E-61 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS12550 79b15da29a9827a5b75f9bdebb1cf2f4 495 Pfam PF07690 Major Facilitator Superfamily 38 438 8.1E-45 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS18350 411c55a9ca5ea922b67ce1acc4cb80d9 147 Pfam PF03061 Thioesterase superfamily 57 134 1.2E-17 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 UA74_RS18350 411c55a9ca5ea922b67ce1acc4cb80d9 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 29 142 1.9E-27 T 09-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 UA74_RS18350 411c55a9ca5ea922b67ce1acc4cb80d9 147 SUPERFAMILY SSF54637 17 142 2.49E-36 T 09-03-2017 IPR029069 HotDog domain UA74_RS18350 411c55a9ca5ea922b67ce1acc4cb80d9 147 Gene3D G3DSA:3.10.129.10 10 145 1.1E-44 T 09-03-2017 IPR029069 HotDog domain UA74_RS06000 150bcc36ff39e9b31813abfffd4db3d1 473 SUPERFAMILY SSF53092 46 201 2.98E-22 T 09-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal UA74_RS06000 150bcc36ff39e9b31813abfffd4db3d1 473 SUPERFAMILY SSF55920 203 469 3.79E-55 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS06000 150bcc36ff39e9b31813abfffd4db3d1 473 Pfam PF05195 Aminopeptidase P, N-terminal domain 46 163 7.4E-18 T 09-03-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 UA74_RS06000 150bcc36ff39e9b31813abfffd4db3d1 473 Gene3D G3DSA:3.90.230.10 207 462 3.5E-57 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS06000 150bcc36ff39e9b31813abfffd4db3d1 473 Pfam PF00557 Metallopeptidase family M24 210 447 3.6E-43 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS06000 150bcc36ff39e9b31813abfffd4db3d1 473 Gene3D G3DSA:3.40.350.10 42 206 2.0E-29 T 09-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_RS06000 150bcc36ff39e9b31813abfffd4db3d1 473 SMART SM01011 43 180 8.9E-33 T 09-03-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 UA74_RS25660 914e10fbe439c61987ddfe444838c9d4 243 Gene3D G3DSA:1.10.101.10 35 106 1.4E-20 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS25660 914e10fbe439c61987ddfe444838c9d4 243 Pfam PF01471 Putative peptidoglycan binding domain 44 105 3.7E-12 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS25660 914e10fbe439c61987ddfe444838c9d4 243 Gene3D G3DSA:3.30.1380.10 117 235 6.0E-30 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS25660 914e10fbe439c61987ddfe444838c9d4 243 SUPERFAMILY SSF55166 117 230 3.92E-28 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS25660 914e10fbe439c61987ddfe444838c9d4 243 SUPERFAMILY SSF47090 33 108 1.88E-17 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS25660 914e10fbe439c61987ddfe444838c9d4 243 Pfam PF08291 Peptidase M15 117 227 7.1E-22 T 09-03-2017 IPR013230 Peptidase M15A, C-terminal MetaCyc: PWY-6470 UA74_RS27675 2dcb8eb542b797fcfae98783f686cc96 385 SUPERFAMILY SSF53822 86 300 2.24E-6 T 09-03-2017 IPR028082 Periplasmic binding protein-like I UA74_RS27675 2dcb8eb542b797fcfae98783f686cc96 385 Pfam PF02608 Basic membrane protein 79 381 9.8E-49 T 09-03-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 UA74_RS27675 2dcb8eb542b797fcfae98783f686cc96 385 Gene3D G3DSA:3.40.50.2300 182 350 1.3E-42 T 09-03-2017 UA74_RS21710 cb570c8b0d920e0a0ff1ca043f83a3cf 180 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 20 143 1.6E-23 T 09-03-2017 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_RS21710 cb570c8b0d920e0a0ff1ca043f83a3cf 180 SUPERFAMILY SSF54427 17 148 1.72E-34 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS21710 cb570c8b0d920e0a0ff1ca043f83a3cf 180 Gene3D G3DSA:3.10.450.50 12 150 1.3E-37 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS21710 cb570c8b0d920e0a0ff1ca043f83a3cf 180 Pfam PF14534 Domain of unknown function (DUF4440) 24 135 1.6E-12 T 09-03-2017 IPR027843 Domain of unknown function DUF4440 UA74_RS29995 01245171c2231b614a4ee34a9365be65 613 Pfam PF00350 Dynamin family 50 203 1.2E-13 T 09-03-2017 IPR022812 Dynamin superfamily UA74_RS29995 01245171c2231b614a4ee34a9365be65 613 Gene3D G3DSA:3.40.50.300 121 150 6.8E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29995 01245171c2231b614a4ee34a9365be65 613 Gene3D G3DSA:3.40.50.300 18 59 6.8E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29995 01245171c2231b614a4ee34a9365be65 613 SUPERFAMILY SSF52540 44 279 9.19E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29995 01245171c2231b614a4ee34a9365be65 613 Gene3D G3DSA:3.40.50.300 60 93 6.1E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29995 01245171c2231b614a4ee34a9365be65 613 Gene3D G3DSA:3.40.50.300 151 252 6.1E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04890 46b55d6093b178b6986c76a6bc032985 198 SUPERFAMILY SSF48498 86 183 3.26E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS04890 46b55d6093b178b6986c76a6bc032985 198 SUPERFAMILY SSF46689 14 86 3.9E-18 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS04890 46b55d6093b178b6986c76a6bc032985 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04890 46b55d6093b178b6986c76a6bc032985 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.7E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04890 46b55d6093b178b6986c76a6bc032985 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 7.7E-17 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04890 46b55d6093b178b6986c76a6bc032985 198 Gene3D G3DSA:1.10.357.10 17 181 8.2E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS07130 f52b0b336a71f6a8583ccf343ceedbe0 427 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 12 424 49.398 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UA74_RS07130 f52b0b336a71f6a8583ccf343ceedbe0 427 Gene3D G3DSA:3.40.640.10 42 287 4.0E-103 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS07130 f52b0b336a71f6a8583ccf343ceedbe0 427 PIRSF PIRSF000412 8 424 5.2E-158 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UA74_RS07130 f52b0b336a71f6a8583ccf343ceedbe0 427 Pfam PF00464 Serine hydroxymethyltransferase 13 389 3.6E-155 T 09-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UA74_RS07130 f52b0b336a71f6a8583ccf343ceedbe0 427 Gene3D G3DSA:3.90.1150.10 288 424 4.5E-46 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS07130 f52b0b336a71f6a8583ccf343ceedbe0 427 SUPERFAMILY SSF53383 12 424 3.16E-162 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 Pfam PF09448 Methylmuconolactone methyl-isomerase 123 227 1.0E-12 T 09-03-2017 IPR018566 4-Methylmuconolactone methyl-isomerase UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 131 214 4.6E-13 T 09-03-2017 IPR009799 EthD domain UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 4 82 3.4E-8 T 09-03-2017 IPR009799 EthD domain UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 Gene3D G3DSA:3.30.70.900 2 101 3.1E-17 T 09-03-2017 UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 Gene3D G3DSA:3.30.70.900 125 212 9.7E-20 T 09-03-2017 UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 SUPERFAMILY SSF54909 122 225 1.53E-26 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 Pfam PF07110 EthD domain 12 93 5.6E-10 T 09-03-2017 IPR009799 EthD domain UA74_RS07675 78a56e27a6c6d9b45831bbcc660b6b35 231 SUPERFAMILY SSF54909 2 103 4.69E-19 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS20315 302188a43473550878d3f43f9bdc5b23 398 Gene3D G3DSA:1.10.10.10 268 397 5.2E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20315 302188a43473550878d3f43f9bdc5b23 398 SUPERFAMILY SSF46785 268 397 7.88E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS11180 2b2cca74d8d4fcad385d1b33277d7696 233 Gene3D G3DSA:3.60.15.10 6 226 1.5E-51 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS11180 2b2cca74d8d4fcad385d1b33277d7696 233 Pfam PF00753 Metallo-beta-lactamase superfamily 9 209 4.4E-24 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS11180 2b2cca74d8d4fcad385d1b33277d7696 233 SUPERFAMILY SSF56281 6 226 5.96E-49 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS11180 2b2cca74d8d4fcad385d1b33277d7696 233 SMART SM00849 12 209 9.4E-35 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS04160 7f3238139c2237beda31c9f51ba285b4 197 Gene3D G3DSA:1.10.10.10 118 181 1.2E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04160 7f3238139c2237beda31c9f51ba285b4 197 SUPERFAMILY SSF88659 119 181 2.43E-11 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04160 7f3238139c2237beda31c9f51ba285b4 197 SUPERFAMILY SSF88946 13 97 1.49E-15 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04160 7f3238139c2237beda31c9f51ba285b4 197 Pfam PF08281 Sigma-70, region 4 126 176 1.5E-12 T 09-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04160 7f3238139c2237beda31c9f51ba285b4 197 Pfam PF04542 Sigma-70 region 2 23 91 2.2E-10 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS04160 7f3238139c2237beda31c9f51ba285b4 197 Gene3D G3DSA:1.10.1740.10 14 110 4.2E-17 T 09-03-2017 UA74_RS04160 7f3238139c2237beda31c9f51ba285b4 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 180 3.8E-19 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 Gene3D G3DSA:3.40.30.10 5 111 1.9E-33 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 Pfam PF00085 Thioredoxin 10 110 2.0E-30 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 PRINTS PR00421 Thioredoxin family signature 37 46 4.3E-7 T 09-03-2017 UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 PRINTS PR00421 Thioredoxin family signature 77 88 4.3E-7 T 09-03-2017 UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 PRINTS PR00421 Thioredoxin family signature 29 37 4.3E-7 T 09-03-2017 UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 PIRSF PIRSF000077 7 113 2.7E-38 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 TIGRFAM TIGR01068 thioredoxin: thioredoxin 14 110 9.6E-34 T 09-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 SUPERFAMILY SSF52833 6 113 6.86E-37 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS19605 45ece54cc9963b9e3c38a34f26615677 115 ProSitePatterns PS00194 Thioredoxin family active site. 30 48 - T 09-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_RS07695 d00b3d92616f59d740efc4f755e52a5f 200 Gene3D G3DSA:3.40.50.880 11 199 3.7E-29 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS07695 d00b3d92616f59d740efc4f755e52a5f 200 Pfam PF01965 DJ-1/PfpI family 16 193 1.2E-13 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS07695 d00b3d92616f59d740efc4f755e52a5f 200 SUPERFAMILY SSF52317 15 198 3.51E-20 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS14485 121a9904faee609ec435187f69206824 1281 Pfam PF04261 Dyp-type peroxidase family 110 345 1.2E-11 T 09-03-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 UA74_RS14485 121a9904faee609ec435187f69206824 1281 SUPERFAMILY SSF51998 504 824 1.01E-100 T 09-03-2017 UA74_RS14485 121a9904faee609ec435187f69206824 1281 SUPERFAMILY SSF51998 1046 1273 1.01E-100 T 09-03-2017 UA74_RS14485 121a9904faee609ec435187f69206824 1281 SUPERFAMILY SSF51998 859 1006 1.01E-100 T 09-03-2017 UA74_RS14485 121a9904faee609ec435187f69206824 1281 SUPERFAMILY SSF54909 11 347 8.4E-31 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS14485 121a9904faee609ec435187f69206824 1281 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 12 347 2.1E-31 T 09-03-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 UA74_RS14485 121a9904faee609ec435187f69206824 1281 Pfam PF02901 Pyruvate formate lyase-like 539 1090 5.7E-126 T 09-03-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 UA74_RS14485 121a9904faee609ec435187f69206824 1281 Gene3D G3DSA:3.20.70.20 539 822 3.2E-116 T 09-03-2017 UA74_RS14485 121a9904faee609ec435187f69206824 1281 Gene3D G3DSA:3.20.70.20 857 1268 3.2E-116 T 09-03-2017 UA74_RS01785 fb9c3aa1aef49eb07491544d2c9634bd 490 Pfam PF00982 Glycosyltransferase family 20 23 484 4.0E-150 T 09-03-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 UA74_RS01785 fb9c3aa1aef49eb07491544d2c9634bd 490 SUPERFAMILY SSF53756 22 486 4.92E-143 T 09-03-2017 UA74_RS01785 fb9c3aa1aef49eb07491544d2c9634bd 490 Gene3D G3DSA:3.40.50.2000 273 470 7.9E-73 T 09-03-2017 UA74_RS01785 fb9c3aa1aef49eb07491544d2c9634bd 490 Gene3D G3DSA:3.40.50.2000 22 272 3.0E-83 T 09-03-2017 UA74_RS11895 44a5b9c3023efdf42ba01cf3da625fa8 225 Pfam PF06283 Trehalose utilisation 10 220 7.2E-73 T 09-03-2017 IPR029010 ThuA-like domain UA74_RS11895 44a5b9c3023efdf42ba01cf3da625fa8 225 SUPERFAMILY SSF52317 7 222 1.24E-43 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS11895 44a5b9c3023efdf42ba01cf3da625fa8 225 Gene3D G3DSA:3.40.50.880 9 222 2.4E-38 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS06845 b1289b023bf10dd249732e8573030e36 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 282 1.2E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS06845 b1289b023bf10dd249732e8573030e36 292 SUPERFAMILY SSF161098 20 292 3.64E-64 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS06845 b1289b023bf10dd249732e8573030e36 292 Gene3D G3DSA:1.10.3720.10 17 278 2.8E-56 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS10320 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 120 197 6.8E-9 T 09-03-2017 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 UA74_RS10320 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 SMART SM00487 278 505 4.8E-9 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS10320 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 Gene3D G3DSA:3.40.50.300 279 477 1.1E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10320 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 Pfam PF04851 Type III restriction enzyme, res subunit 282 474 7.3E-13 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_RS10320 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 SUPERFAMILY SSF52540 243 530 4.47E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05820 33430b2029bd533e5ad3abd65c801b17 242 Gene3D G3DSA:3.40.109.10 10 240 1.7E-29 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS05820 33430b2029bd533e5ad3abd65c801b17 242 Pfam PF00881 Nitroreductase family 18 217 1.9E-19 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_RS05820 33430b2029bd533e5ad3abd65c801b17 242 SUPERFAMILY SSF55469 10 73 4.23E-29 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS05820 33430b2029bd533e5ad3abd65c801b17 242 SUPERFAMILY SSF55469 106 241 4.23E-29 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS26180 b133b9cbbb685d93d5dd6b8ca700d63e 310 Pfam PF07681 DoxX 155 239 5.0E-19 T 09-03-2017 IPR032808 DoxX family UA74_RS05585 0b947d1cc2d14761d39e2418d897c528 415 Gene3D G3DSA:1.20.1250.20 225 406 1.4E-18 T 09-03-2017 UA74_RS05585 0b947d1cc2d14761d39e2418d897c528 415 Gene3D G3DSA:1.20.1250.20 20 206 3.3E-24 T 09-03-2017 UA74_RS05585 0b947d1cc2d14761d39e2418d897c528 415 SUPERFAMILY SSF103473 14 403 5.75E-53 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS05585 0b947d1cc2d14761d39e2418d897c528 415 Pfam PF07690 Major Facilitator Superfamily 29 351 1.5E-31 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS22270 13ff9657406fdfe4b3f85254bcbd718f 497 SUPERFAMILY SSF51556 168 455 1.36E-61 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS22270 13ff9657406fdfe4b3f85254bcbd718f 497 Gene3D G3DSA:2.30.40.10 8 80 7.8E-14 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS22270 13ff9657406fdfe4b3f85254bcbd718f 497 SUPERFAMILY SSF51338 4 58 1.39E-16 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS22270 13ff9657406fdfe4b3f85254bcbd718f 497 SUPERFAMILY SSF51338 455 487 1.39E-16 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS22270 13ff9657406fdfe4b3f85254bcbd718f 497 Pfam PF01979 Amidohydrolase family 179 470 9.0E-15 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS22270 13ff9657406fdfe4b3f85254bcbd718f 497 Gene3D G3DSA:3.20.20.140 162 442 1.6E-67 T 09-03-2017 UA74_RS22270 13ff9657406fdfe4b3f85254bcbd718f 497 Gene3D G3DSA:2.30.40.10 443 485 4.1E-5 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS05985 2218aa7255378c53aca4d390e6cdfdda 194 Pfam PF12464 Maltose acetyltransferase 18 68 2.5E-6 T 09-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 UA74_RS05985 2218aa7255378c53aca4d390e6cdfdda 194 Gene3D G3DSA:2.160.10.10 13 194 9.0E-53 T 09-03-2017 UA74_RS05985 2218aa7255378c53aca4d390e6cdfdda 194 SMART SM01266 16 69 9.5E-8 T 09-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 UA74_RS05985 2218aa7255378c53aca4d390e6cdfdda 194 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 149 177 - T 09-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UA74_RS05985 2218aa7255378c53aca4d390e6cdfdda 194 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 141 175 2.6E-9 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS05985 2218aa7255378c53aca4d390e6cdfdda 194 SUPERFAMILY SSF51161 27 192 3.1E-46 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 Gene3D G3DSA:3.40.50.720 6 248 7.1E-72 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 SUPERFAMILY SSF51735 8 248 7.38E-69 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.0E-39 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS20420 87e6fa7c5a68b8344a64c3aa6d46b40c 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 247 5.2E-55 T 09-03-2017 UA74_RS05055 202f265d7e62280126adffed9147cd96 85 SMART SM00966 1 43 0.0019 T 09-03-2017 IPR007159 SpoVT-AbrB domain GO:0003677 UA74_RS05055 202f265d7e62280126adffed9147cd96 85 SUPERFAMILY SSF89447 3 62 7.5E-8 T 09-03-2017 UA74_RS05055 202f265d7e62280126adffed9147cd96 85 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 38 1.2E-8 T 09-03-2017 IPR007159 SpoVT-AbrB domain GO:0003677 UA74_RS05055 202f265d7e62280126adffed9147cd96 85 Gene3D G3DSA:2.10.260.10 5 38 3.4E-6 T 09-03-2017 UA74_RS05055 202f265d7e62280126adffed9147cd96 85 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 35 5.2E-6 T 09-03-2017 IPR007159 SpoVT-AbrB domain GO:0003677 UA74_RS29260 10fecaa59df713a5ddc35521aa90ce8c 276 SMART SM00530 9 64 3.0E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS29260 10fecaa59df713a5ddc35521aa90ce8c 276 Gene3D G3DSA:1.10.260.40 3 62 3.4E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS29260 10fecaa59df713a5ddc35521aa90ce8c 276 SUPERFAMILY SSF47413 4 60 2.53E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS29260 10fecaa59df713a5ddc35521aa90ce8c 276 Pfam PF13560 Helix-turn-helix domain 6 67 6.7E-14 T 09-03-2017 UA74_RS14935 a750bb47fe62dfc23cac95df87ad4262 314 Gene3D G3DSA:3.40.50.150 137 271 4.3E-13 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14935 a750bb47fe62dfc23cac95df87ad4262 314 Pfam PF13649 Methyltransferase domain 174 263 6.4E-9 T 09-03-2017 UA74_RS14935 a750bb47fe62dfc23cac95df87ad4262 314 SUPERFAMILY SSF53335 167 271 5.94E-17 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15330 2469feb575ce6b5d5ad6c2a783a5fae7 115 SUPERFAMILY SSF54909 2 111 4.83E-25 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS15330 2469feb575ce6b5d5ad6c2a783a5fae7 115 Pfam PF03795 YCII-related domain 2 110 3.9E-18 T 09-03-2017 IPR005545 YCII-related UA74_RS15330 2469feb575ce6b5d5ad6c2a783a5fae7 115 Gene3D G3DSA:3.30.70.1060 2 112 1.1E-33 T 09-03-2017 UA74_RS19150 c9b31d27a8a08de7d123acd1d74a0c66 268 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS19150 c9b31d27a8a08de7d123acd1d74a0c66 268 SMART SM00382 35 224 9.5E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS19150 c9b31d27a8a08de7d123acd1d74a0c66 268 Pfam PF00005 ABC transporter 26 167 6.7E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS19150 c9b31d27a8a08de7d123acd1d74a0c66 268 SUPERFAMILY SSF52540 6 226 6.37E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19150 c9b31d27a8a08de7d123acd1d74a0c66 268 Gene3D G3DSA:3.40.50.300 5 228 3.7E-66 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10365 999f19d6fa575e2d69149606745d7663 484 SUPERFAMILY SSF48317 54 203 3.01E-30 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS10365 999f19d6fa575e2d69149606745d7663 484 SMART SM00014 93 202 2.9E-13 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS10365 999f19d6fa575e2d69149606745d7663 484 Gene3D G3DSA:1.20.144.10 50 202 8.4E-30 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS10365 999f19d6fa575e2d69149606745d7663 484 Pfam PF01569 PAP2 superfamily 95 202 4.2E-23 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS02580 dae7191229beaf56e2fc0e8c998b1928 188 Pfam PF12838 4Fe-4S dicluster domain 52 110 5.1E-11 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_RS02580 dae7191229beaf56e2fc0e8c998b1928 188 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 2.6E-39 T 09-03-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02580 dae7191229beaf56e2fc0e8c998b1928 188 SUPERFAMILY SSF54862 26 141 2.55E-25 T 09-03-2017 UA74_RS02580 dae7191229beaf56e2fc0e8c998b1928 188 Gene3D G3DSA:1.10.1060.10 4 114 2.0E-19 T 09-03-2017 UA74_RS02580 dae7191229beaf56e2fc0e8c998b1928 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS02580 dae7191229beaf56e2fc0e8c998b1928 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS02580 dae7191229beaf56e2fc0e8c998b1928 188 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 146 26.782 T 09-03-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS24375 1fbb990fc6b0f4a094f6360741891468 211 SUPERFAMILY SSF55136 126 195 3.14E-9 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain UA74_RS24375 1fbb990fc6b0f4a094f6360741891468 211 PIRSF PIRSF031644 2 206 3.4E-63 T 09-03-2017 IPR008319 Uncharacterised conserved protein UCP031644 UA74_RS24375 1fbb990fc6b0f4a094f6360741891468 211 Pfam PF06445 GyrI-like small molecule binding domain 20 201 3.2E-21 T 09-03-2017 IPR029442 GyrI-like small molecule binding domain UA74_RS24375 1fbb990fc6b0f4a094f6360741891468 211 Gene3D G3DSA:3.20.80.10 2 203 7.9E-78 T 09-03-2017 IPR011256 Regulatory factor, effector binding domain UA74_RS01790 cc8b769758873e352606f063a525977c 472 Pfam PF12821 Threonine/Serine exporter, ThrE 311 439 1.7E-17 T 09-03-2017 IPR024528 Threonine/Serine exporter, ThrE UA74_RS01790 cc8b769758873e352606f063a525977c 472 Pfam PF06738 Putative threonine/serine exporter 42 285 8.6E-58 T 09-03-2017 IPR010619 Putative threonine/serine exporter UA74_RS23365 dd2834cd9e089973f1c7209a6530ef92 122 Pfam PF13788 Domain of unknown function (DUF4180) 9 118 1.3E-39 T 09-03-2017 IPR025438 Domain of unknown function DUF4180 UA74_RS24495 b1ee6492d9328cb24b530a2b955933f4 210 SUPERFAMILY SSF63817 53 205 8.44E-11 T 09-03-2017 IPR023365 Sortase domain UA74_RS24495 b1ee6492d9328cb24b530a2b955933f4 210 Pfam PF04203 Sortase family 105 203 7.4E-9 T 09-03-2017 IPR005754 Sortase family UA74_RS24495 b1ee6492d9328cb24b530a2b955933f4 210 Gene3D G3DSA:2.40.260.10 107 200 3.2E-5 T 09-03-2017 IPR023365 Sortase domain UA74_RS19995 acd7126f11ba09a18bde3d02924034d4 380 SUPERFAMILY SSF53300 217 358 7.19E-18 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS19995 acd7126f11ba09a18bde3d02924034d4 380 Pfam PF05762 VWA domain containing CoxE-like protein 154 371 1.4E-53 T 09-03-2017 IPR008912 Uncharacterised protein family CoxE-like UA74_RS19995 acd7126f11ba09a18bde3d02924034d4 380 Gene3D G3DSA:3.40.50.410 218 337 4.7E-5 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS19995 acd7126f11ba09a18bde3d02924034d4 380 SMART SM00327 216 378 2.6E-7 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS24685 7dea9991485d0456fa2016155490fc99 279 Gene3D G3DSA:3.40.50.150 58 177 1.4E-11 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24685 7dea9991485d0456fa2016155490fc99 279 SUPERFAMILY SSF53335 61 188 1.13E-15 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24685 7dea9991485d0456fa2016155490fc99 279 Pfam PF13489 Methyltransferase domain 56 187 1.7E-6 T 09-03-2017 UA74_RS23875 d0f98857da1ee775d715dbc6471ae256 413 Gene3D G3DSA:3.40.190.10 11 134 7.7E-33 T 09-03-2017 UA74_RS23875 d0f98857da1ee775d715dbc6471ae256 413 Gene3D G3DSA:3.40.190.10 309 358 7.7E-33 T 09-03-2017 UA74_RS23875 d0f98857da1ee775d715dbc6471ae256 413 SUPERFAMILY SSF53850 19 412 9.83E-57 T 09-03-2017 UA74_RS23875 d0f98857da1ee775d715dbc6471ae256 413 Gene3D G3DSA:3.40.190.10 141 308 2.2E-16 T 09-03-2017 UA74_RS23875 d0f98857da1ee775d715dbc6471ae256 413 Pfam PF01547 Bacterial extracellular solute-binding protein 36 321 4.4E-25 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS17145 b73e2592c1a79a229f9cda5efc714bde 447 SUPERFAMILY SSF103473 20 420 1.57E-58 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS17145 b73e2592c1a79a229f9cda5efc714bde 447 Gene3D G3DSA:1.20.1250.20 20 222 4.2E-27 T 09-03-2017 UA74_RS17145 b73e2592c1a79a229f9cda5efc714bde 447 Gene3D G3DSA:1.20.1250.20 241 426 1.4E-16 T 09-03-2017 UA74_RS17145 b73e2592c1a79a229f9cda5efc714bde 447 Pfam PF07690 Major Facilitator Superfamily 72 385 2.4E-28 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS05005 b1358bf6ad32e232488a713d1dfbeb18 71 Gene3D G3DSA:1.10.10.10 27 70 8.9E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08855 d2a7772662ae881ada5134a6d1ada16c 155 SUPERFAMILY SSF46785 36 149 3.9E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS08855 d2a7772662ae881ada5134a6d1ada16c 155 Pfam PF12802 MarR family 59 99 1.5E-7 T 09-03-2017 UA74_RS08855 d2a7772662ae881ada5134a6d1ada16c 155 SMART SM00347 31 135 0.0033 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS08855 d2a7772662ae881ada5134a6d1ada16c 155 Gene3D G3DSA:1.10.10.10 38 147 9.8E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12015 6fe94298e95f4385a5085bbe296e1415 373 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 45 357 5.7E-129 T 09-03-2017 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UA74_RS12015 6fe94298e95f4385a5085bbe296e1415 373 Gene3D G3DSA:3.40.50.970 40 359 1.8E-123 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12015 6fe94298e95f4385a5085bbe296e1415 373 SUPERFAMILY SSF52518 41 359 2.86E-98 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS12015 6fe94298e95f4385a5085bbe296e1415 373 Pfam PF00676 Dehydrogenase E1 component 52 348 3.1E-81 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 UA74_RS13065 0ff42c8ccd1eefb41cc15b961ec207cb 359 SUPERFAMILY SSF52266 44 328 8.49E-39 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS13065 0ff42c8ccd1eefb41cc15b961ec207cb 359 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 46 319 6.1E-15 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS13065 0ff42c8ccd1eefb41cc15b961ec207cb 359 Gene3D G3DSA:3.40.50.1110 38 328 1.4E-39 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS07475 65b3cef70939886b87684881ed35920d 92 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 25 82 3.5E-7 T 09-03-2017 IPR026496 Putative ATP-grasp target RiPP UA74_RS20320 7a693508381bbe43972cbbf3aea7498e 278 SMART SM00342 183 266 8.6E-10 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS20320 7a693508381bbe43972cbbf3aea7498e 278 Gene3D G3DSA:1.10.10.60 220 266 9.1E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20320 7a693508381bbe43972cbbf3aea7498e 278 Gene3D G3DSA:1.10.10.60 169 219 1.7E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20320 7a693508381bbe43972cbbf3aea7498e 278 Pfam PF12833 Helix-turn-helix domain 190 266 6.0E-14 T 09-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_RS08745 e678806d1c72d7444b038a435f4d194b 160 Pfam PF03477 ATP cone domain 47 132 1.1E-14 T 09-03-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 UA74_RS08745 e678806d1c72d7444b038a435f4d194b 160 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 2 144 6.2E-50 T 09-03-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 UA74_RS08745 e678806d1c72d7444b038a435f4d194b 160 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 78.377 T 09-03-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 UA74_RS23955 da75ca22e3dda2233645b3a7b5cb2a0a 107 Pfam PF05336 Domain of unknown function (DUF718) 4 106 1.5E-28 T 09-03-2017 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UA74_RS23955 da75ca22e3dda2233645b3a7b5cb2a0a 107 SUPERFAMILY SSF54909 3 107 6.43E-30 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 240 2.0E-58 T 09-03-2017 UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 SUPERFAMILY SSF51735 5 240 2.88E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.1E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.1E-5 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 Gene3D G3DSA:3.40.50.720 2 241 4.8E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.4E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.4E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.4E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.4E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS06900 9366db6a56c6f0f61113ba51d49502fd 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 SUPERFAMILY SSF53474 377 493 1.15E-14 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 SUPERFAMILY SSF53474 217 271 1.15E-14 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 SUPERFAMILY SSF53474 116 172 1.15E-14 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 Pfam PF08386 TAP-like protein 421 520 1.1E-19 T 09-03-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 Gene3D G3DSA:3.40.50.1820 391 505 1.9E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 Gene3D G3DSA:3.40.50.1820 111 171 1.9E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 Gene3D G3DSA:3.40.50.1820 215 342 1.9E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23770 7ca5f357e94cb31fc8b7ea142042118a 522 Pfam PF00561 alpha/beta hydrolase fold 141 343 1.0E-12 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS26325 fb0294123c69ea0e42b29db33038d768 213 Pfam PF01614 Bacterial transcriptional regulator 144 187 1.7E-4 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS26325 fb0294123c69ea0e42b29db33038d768 213 SUPERFAMILY SSF55781 68 209 8.5E-22 T 09-03-2017 IPR029016 GAF domain-like UA74_RS26325 fb0294123c69ea0e42b29db33038d768 213 SMART SM00346 1 81 7.6E-8 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS26325 fb0294123c69ea0e42b29db33038d768 213 SUPERFAMILY SSF46785 1 66 4.62E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26325 fb0294123c69ea0e42b29db33038d768 213 Gene3D G3DSA:1.10.10.10 1 67 9.9E-15 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26325 fb0294123c69ea0e42b29db33038d768 213 Pfam PF09339 IclR helix-turn-helix domain 1 45 1.7E-6 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS26325 fb0294123c69ea0e42b29db33038d768 213 Gene3D G3DSA:3.30.450.40 68 209 1.7E-19 T 09-03-2017 IPR029016 GAF domain-like UA74_RS22465 90696d20f9021f7931839979fca9dde4 397 Gene3D G3DSA:1.20.1250.20 4 180 1.3E-16 T 09-03-2017 UA74_RS22465 90696d20f9021f7931839979fca9dde4 397 Gene3D G3DSA:1.20.1250.20 203 383 9.2E-16 T 09-03-2017 UA74_RS22465 90696d20f9021f7931839979fca9dde4 397 SUPERFAMILY SSF103473 2 382 1.83E-41 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22465 90696d20f9021f7931839979fca9dde4 397 Pfam PF05977 Transmembrane secretion effector 1 379 1.1E-32 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS16310 6870b5c2fde051cfbfef27239962a695 376 Pfam PF12666 PrgI family protein 6 93 2.4E-14 T 09-03-2017 IPR024414 Uncharacterised protein family PrgI UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 Gene3D G3DSA:3.40.50.300 508 593 6.6E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 Gene3D G3DSA:3.40.50.300 330 365 6.6E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 SUPERFAMILY SSF52540 314 365 5.6E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 SUPERFAMILY SSF52540 47 223 5.6E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 SUPERFAMILY SSF52540 508 582 5.6E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 SMART SM00490 493 577 1.5E-11 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 Pfam PF00271 Helicase conserved C-terminal domain 512 577 1.3E-11 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 SMART SM00487 33 248 5.1E-30 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 Pfam PF00270 DEAD/DEAH box helicase 38 223 8.5E-22 T 09-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 Gene3D G3DSA:3.40.50.300 24 230 3.0E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24740 37bfe138eb5fde1eb5b72869f9c93bd7 1757 Pfam PF08494 DEAD/H associated 840 1033 1.4E-72 T 09-03-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 UA74_RS16645 bf34672adb5657459ea8da7e06eaba4b 504 Gene3D G3DSA:3.90.76.10 52 177 3.6E-13 T 09-03-2017 UA74_RS16645 bf34672adb5657459ea8da7e06eaba4b 504 Gene3D G3DSA:3.10.105.10 301 468 1.1E-30 T 09-03-2017 UA74_RS16645 bf34672adb5657459ea8da7e06eaba4b 504 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 409 6.7E-60 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS16645 bf34672adb5657459ea8da7e06eaba4b 504 SUPERFAMILY SSF53850 39 492 1.39E-79 T 09-03-2017 UA74_RS16645 bf34672adb5657459ea8da7e06eaba4b 504 Gene3D G3DSA:3.40.190.10 185 300 5.1E-28 T 09-03-2017 UA74_RS17175 822530f4634172dc22c1e4e79458696d 522 Pfam PF16861 Carbamoyltransferase C-terminus 354 517 1.4E-52 T 09-03-2017 IPR031730 Carbamoyltransferase, C-terminal UA74_RS17175 822530f4634172dc22c1e4e79458696d 522 Pfam PF02543 Carbamoyltransferase N-terminus 101 308 6.5E-17 T 09-03-2017 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 UA74_RS26700 639c635354a01fec28a2322203292f09 505 Pfam PF06974 Protein of unknown function (DUF1298) 356 501 3.2E-25 T 09-03-2017 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 UA74_RS26700 639c635354a01fec28a2322203292f09 505 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 289 7.7E-75 T 09-03-2017 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 UA74_RS26700 639c635354a01fec28a2322203292f09 505 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 503 2.5E-133 T 09-03-2017 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 UA74_RS26700 639c635354a01fec28a2322203292f09 505 SUPERFAMILY SSF52777 53 164 1.56E-6 T 09-03-2017 UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 SUPERFAMILY SSF69742 1 158 9.68E-42 T 09-03-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 421 25.229 T 09-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.4E-40 T 09-03-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 424 5.5E-117 T 09-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 09-03-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 310 2.9E-27 T 09-03-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 SUPERFAMILY SSF69075 322 424 1.57E-15 T 09-03-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 Gene3D G3DSA:3.40.50.720 173 310 3.9E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 SUPERFAMILY SSF51735 164 309 5.23E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02300 716e8b1198409f5bc1a2c1d12bb24403 589 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 325 423 5.3E-20 T 09-03-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_RS11755 fdf54f1d30c364421bb71ddf15a62eea 241 Gene3D G3DSA:2.10.25.10 72 104 9.8E-4 T 09-03-2017 UA74_RS11755 fdf54f1d30c364421bb71ddf15a62eea 241 Gene3D G3DSA:2.60.200.20 142 231 5.4E-18 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS11755 fdf54f1d30c364421bb71ddf15a62eea 241 SMART SM00240 153 210 1.3E-7 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS11755 fdf54f1d30c364421bb71ddf15a62eea 241 Pfam PF00498 FHA domain 156 228 5.3E-11 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS11755 fdf54f1d30c364421bb71ddf15a62eea 241 SUPERFAMILY SSF49879 127 232 2.49E-18 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 UA74_RS22150 cd4622415c663ce6c753200f08655fa2 124 Pfam PF10012 Uncharacterized protein conserved in bacteria (DUF2255) 8 121 2.6E-38 T 09-03-2017 IPR016888 Uncharacterised conserved protein UCP028498 UA74_RS22150 cd4622415c663ce6c753200f08655fa2 124 Gene3D G3DSA:2.30.110.10 6 123 2.5E-4 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS22150 cd4622415c663ce6c753200f08655fa2 124 SUPERFAMILY SSF50475 6 68 8.18E-5 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS29845 607ec24b3b7ed9103cb38a350551e1e0 399 SUPERFAMILY SSF48208 24 294 3.0E-23 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS29845 607ec24b3b7ed9103cb38a350551e1e0 399 Gene3D G3DSA:1.50.10.10 28 261 1.2E-17 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS29845 607ec24b3b7ed9103cb38a350551e1e0 399 Pfam PF03663 Glycosyl hydrolase family 76 32 329 3.7E-26 T 09-03-2017 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 UA74_RS08475 1e97f0fddaef8168286ee720e437a9ae 87 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 6.5E-28 T 09-03-2017 IPR021400 Protein of unknown function DUF3039 UA74_RS12115 f268518d5972df96a04b919ccb75dbb0 484 SUPERFAMILY SSF53383 30 471 7.89E-105 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS12115 f268518d5972df96a04b919ccb75dbb0 484 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 86 404 6.5E-46 T 09-03-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UA74_RS12115 f268518d5972df96a04b919ccb75dbb0 484 Gene3D G3DSA:3.40.640.10 83 357 3.4E-78 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS12115 f268518d5972df96a04b919ccb75dbb0 484 Gene3D G3DSA:3.90.1150.10 358 472 4.9E-30 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS10725 7894ce38a49cf8423c58edc6325b0add 308 SUPERFAMILY SSF55729 147 298 4.48E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS10725 7894ce38a49cf8423c58edc6325b0add 308 Gene3D G3DSA:3.40.630.30 147 301 3.8E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS10725 7894ce38a49cf8423c58edc6325b0add 308 Pfam PF00583 Acetyltransferase (GNAT) family 205 293 1.1E-5 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS22210 5af1125613d4b70a5034578a1355399d 693 SUPERFAMILY SSF53474 502 648 1.93E-7 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22210 5af1125613d4b70a5034578a1355399d 693 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 214 244 - T 09-03-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 UA74_RS22210 5af1125613d4b70a5034578a1355399d 693 SUPERFAMILY SSF53474 208 368 2.2E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22210 5af1125613d4b70a5034578a1355399d 693 SUPERFAMILY SSF53474 83 180 2.2E-25 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22210 5af1125613d4b70a5034578a1355399d 693 Gene3D G3DSA:3.40.50.1820 84 366 3.1E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22210 5af1125613d4b70a5034578a1355399d 693 Pfam PF05448 Acetyl xylan esterase (AXE1) 155 260 1.7E-8 T 09-03-2017 IPR008391 Acetyl xylan esterase UA74_RS22210 5af1125613d4b70a5034578a1355399d 693 Gene3D G3DSA:3.40.50.1820 505 655 8.7E-9 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18620 b0fe4b1ce3672740c89f07abecfe4e24 394 Gene3D G3DSA:3.60.60.10 110 368 1.8E-22 T 09-03-2017 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 UA74_RS18620 b0fe4b1ce3672740c89f07abecfe4e24 394 SUPERFAMILY SSF56235 177 365 2.08E-12 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS18620 b0fe4b1ce3672740c89f07abecfe4e24 394 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 156 367 5.4E-15 T 09-03-2017 IPR005079 Peptidase C45 UA74_RS18805 d5361253549afaf55f36d0e3faa5eb09 239 Pfam PF04909 Amidohydrolase 50 239 2.9E-29 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS18805 d5361253549afaf55f36d0e3faa5eb09 239 SUPERFAMILY SSF51556 2 239 3.74E-43 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS18805 d5361253549afaf55f36d0e3faa5eb09 239 Gene3D G3DSA:3.20.20.140 2 239 4.1E-47 T 09-03-2017 UA74_RS09955 b0fbc35e8070240c2f57868d895e31b1 337 SUPERFAMILY SSF56059 142 332 5.71E-13 T 09-03-2017 UA74_RS09955 b0fbc35e8070240c2f57868d895e31b1 337 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 9 332 2.8E-115 T 09-03-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family UA74_RS01435 f0f2897273c5abe9a18a6d1770bca3fe 215 Pfam PF13302 Acetyltransferase (GNAT) domain 48 187 2.4E-23 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS01435 f0f2897273c5abe9a18a6d1770bca3fe 215 SUPERFAMILY SSF55729 42 210 9.9E-39 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS01435 f0f2897273c5abe9a18a6d1770bca3fe 215 Gene3D G3DSA:3.40.630.30 42 210 9.8E-44 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15810 2d89bcff7db76b6f69158fcb5364fd9a 168 Gene3D G3DSA:1.10.10.10 15 122 1.1E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26560 0bc656bb9c35ce5b6d48e43be5225e88 235 SUPERFAMILY SSF161098 23 203 1.23E-33 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS26560 0bc656bb9c35ce5b6d48e43be5225e88 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 214 5.6E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS26560 0bc656bb9c35ce5b6d48e43be5225e88 235 Gene3D G3DSA:1.10.3720.10 24 204 9.9E-25 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18025 ef9d31c3f3aff7fab1c5a24204047ff1 351 SUPERFAMILY SSF50129 4 111 8.48E-18 T 09-03-2017 IPR011032 GroES-like UA74_RS18025 ef9d31c3f3aff7fab1c5a24204047ff1 351 Gene3D G3DSA:3.40.50.720 153 316 3.2E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18025 ef9d31c3f3aff7fab1c5a24204047ff1 351 Gene3D G3DSA:3.90.180.10 2 152 2.8E-29 T 09-03-2017 IPR011032 GroES-like UA74_RS18025 ef9d31c3f3aff7fab1c5a24204047ff1 351 Pfam PF16884 N-terminal domain of oxidoreductase 5 102 2.4E-14 T 09-03-2017 UA74_RS18025 ef9d31c3f3aff7fab1c5a24204047ff1 351 Pfam PF00107 Zinc-binding dehydrogenase 170 293 1.2E-14 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS18025 ef9d31c3f3aff7fab1c5a24204047ff1 351 SMART SM00829 14 349 6.4E-4 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS18025 ef9d31c3f3aff7fab1c5a24204047ff1 351 SUPERFAMILY SSF51735 136 305 1.32E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 Pfam PF01842 ACT domain 4 69 2.5E-18 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 9.6E-64 T 09-03-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 SUPERFAMILY SSF55021 3 76 1.17E-23 T 09-03-2017 UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 74 3.0E-31 T 09-03-2017 UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 Gene3D G3DSA:3.30.70.1150 84 162 1.1E-30 T 09-03-2017 UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 Gene3D G3DSA:3.30.70.260 1 78 1.1E-35 T 09-03-2017 UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 SUPERFAMILY SSF55021 81 162 3.85E-26 T 09-03-2017 UA74_RS26130 cb7b996f4e9d467964c51e9672e36834 168 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.3E-28 T 09-03-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UA74_RS27315 f1c21c41ca597fbe97e62e051daa3322 104 Pfam PF12680 SnoaL-like domain 4 104 2.1E-14 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS27315 f1c21c41ca597fbe97e62e051daa3322 104 SUPERFAMILY SSF54427 4 104 5.19E-24 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS27315 f1c21c41ca597fbe97e62e051daa3322 104 Gene3D G3DSA:3.10.450.50 2 104 1.5E-30 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 13 324 8.0E-96 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 SUPERFAMILY SSF53067 11 326 3.02E-36 T 09-03-2017 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 Gene3D G3DSA:3.30.420.40 11 173 2.4E-43 T 09-03-2017 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 ProSitePatterns PS01016 Glycoprotease family signature. 109 129 - T 09-03-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 89 109 6.4E-51 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 110 129 6.4E-51 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 144 156 6.4E-51 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 168 189 6.4E-51 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 13 26 6.4E-51 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 281 290 6.4E-51 T 09-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 10 350 61.238 T 09-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 12 330 4.1E-124 T 09-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS28120 af5e2502c0abbb46f6537360fa41d21d 355 Pfam PF00814 Glycoprotease family 36 324 6.0E-97 T 09-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 UA74_RS13150 03840b51be7e0b416e70e0285687be6c 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 230 3.4E-19 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS13150 03840b51be7e0b416e70e0285687be6c 353 SUPERFAMILY SSF51735 4 322 1.81E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13150 03840b51be7e0b416e70e0285687be6c 353 Gene3D G3DSA:3.40.50.720 6 316 8.9E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS28510 119802e9add65ac379a925b23440660d 483 Pfam PF11228 Protein of unknown function (DUF3027) 76 266 5.6E-80 T 09-03-2017 IPR021391 Protein of unknown function DUF3027 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF52283 6 137 2.46E-36 T 09-03-2017 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 09-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 1.7E-59 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 09-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 9 527 8.8E-185 T 09-03-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 316 8.8E-34 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.40.50.720 111 286 7.3E-67 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.30.1330.90 323 451 5.2E-39 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.30.70.260 452 519 3.1E-12 T 09-03-2017 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 Pfam PF01842 ACT domain 459 517 3.3E-9 T 09-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF143548 325 453 8.11E-31 T 09-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF51735 103 285 7.41E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF55021 456 526 4.25E-13 T 09-03-2017 UA74_RS26115 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.40.50.720 4 110 1.1E-34 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07910 968d0560c6ba0f94c06acde74fb4de84 490 Pfam PF00561 alpha/beta hydrolase fold 37 419 7.9E-23 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS07910 968d0560c6ba0f94c06acde74fb4de84 490 SUPERFAMILY SSF53474 125 179 4.94E-16 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07910 968d0560c6ba0f94c06acde74fb4de84 490 SUPERFAMILY SSF53474 342 423 4.94E-16 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07910 968d0560c6ba0f94c06acde74fb4de84 490 SUPERFAMILY SSF53474 30 85 4.94E-16 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07910 968d0560c6ba0f94c06acde74fb4de84 490 Gene3D G3DSA:3.40.50.1820 123 247 3.0E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07910 968d0560c6ba0f94c06acde74fb4de84 490 Gene3D G3DSA:3.40.50.1820 318 439 3.0E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07910 968d0560c6ba0f94c06acde74fb4de84 490 Gene3D G3DSA:3.40.50.1820 1 84 3.0E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 8 487 1.7E-152 T 09-03-2017 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 Gene3D G3DSA:3.50.50.60 122 136 1.0E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 Gene3D G3DSA:3.50.50.60 215 296 1.0E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 Gene3D G3DSA:3.50.50.60 7 61 1.0E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 Gene3D G3DSA:3.50.50.60 447 487 1.0E-35 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 SUPERFAMILY SSF51905 447 485 1.26E-63 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 SUPERFAMILY SSF51905 1 315 1.26E-63 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10230 802b063ebe04d2977c7ca4820b4f654d 503 Pfam PF01593 Flavin containing amine oxidoreductase 15 485 5.8E-45 T 09-03-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_RS15290 8afe5066d9999ec99203014f035ee867 1033 Pfam PF13700 Domain of unknown function (DUF4158) 5 170 1.6E-48 T 09-03-2017 IPR025296 Domain of unknown function DUF4158 UA74_RS15290 8afe5066d9999ec99203014f035ee867 1033 Pfam PF01526 Tn3 transposase DDE domain 613 1002 2.0E-131 T 09-03-2017 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 UA74_RS14270 514155752406e22bef3a40762f83889c 220 Hamap MF_00801 Endonuclease V [nfi]. 13 220 28.892 T 09-03-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 UA74_RS14270 514155752406e22bef3a40762f83889c 220 Pfam PF04493 Endonuclease V 25 215 3.1E-64 T 09-03-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 UA74_RS17230 1f5e79cfd0e5b90b6848049e6bcdd197 323 Pfam PF01032 FecCD transport family 2 316 2.2E-96 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS17230 1f5e79cfd0e5b90b6848049e6bcdd197 323 Gene3D G3DSA:1.10.3470.10 2 318 5.0E-107 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS17230 1f5e79cfd0e5b90b6848049e6bcdd197 323 SUPERFAMILY SSF81345 2 316 1.26E-81 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS09885 ca274a1d58895ec49e5232f3374563d0 243 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 202 23.856 T 09-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 UA74_RS09885 ca274a1d58895ec49e5232f3374563d0 243 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 169 2.1E-31 T 09-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 UA74_RS09885 ca274a1d58895ec49e5232f3374563d0 243 Pfam PF13500 AAA domain 4 201 2.2E-33 T 09-03-2017 UA74_RS09885 ca274a1d58895ec49e5232f3374563d0 243 PIRSF PIRSF006755 1 212 1.3E-37 T 09-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 UA74_RS09885 ca274a1d58895ec49e5232f3374563d0 243 Gene3D G3DSA:3.40.50.300 3 201 1.4E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09885 ca274a1d58895ec49e5232f3374563d0 243 SUPERFAMILY SSF52540 1 201 1.22E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28225 811945f28b83c9de99df8b29e1f2d1ba 96 Gene3D G3DSA:1.10.287.1060 5 95 1.6E-20 T 09-03-2017 UA74_RS28225 811945f28b83c9de99df8b29e1f2d1ba 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 3.2E-17 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS28225 811945f28b83c9de99df8b29e1f2d1ba 96 SUPERFAMILY SSF140453 4 95 7.85E-20 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS28225 811945f28b83c9de99df8b29e1f2d1ba 96 Pfam PF06013 Proteins of 100 residues with WXG 5 88 5.6E-13 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 ProSitePatterns PS00018 EF-hand calcium-binding domain. 205 217 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 Pfam PF00656 Caspase domain 7 203 7.9E-11 T 09-03-2017 UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.300 536 647 5.9E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.300 847 946 5.9E-42 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 SUPERFAMILY SSF52129 3 201 2.37E-14 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 Pfam PF13087 AAA domain 919 1099 2.1E-29 T 09-03-2017 UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.1460 5 154 7.9E-10 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 Pfam PF13086 AAA domain 540 887 2.7E-20 T 09-03-2017 UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 SUPERFAMILY SSF52540 538 606 7.78E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 SUPERFAMILY SSF52540 814 884 7.78E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 SUPERFAMILY SSF52540 929 1106 7.78E-43 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21445 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.300 947 1100 3.1E-6 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30230 499fac39b9aa9f35e1566ec6c843238b 347 Pfam PF00487 Fatty acid desaturase 63 321 5.5E-40 T 09-03-2017 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_RS30230 499fac39b9aa9f35e1566ec6c843238b 347 PIRSF PIRSF015921 2 347 5.4E-78 T 09-03-2017 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 UA74_RS30455 8e026094f1de6434897d23db485c1f1a 356 Pfam PF02096 60Kd inner membrane protein 32 247 3.9E-52 T 09-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 UA74_RS30455 8e026094f1de6434897d23db485c1f1a 356 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 32 247 1.1E-57 T 09-03-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal UA74_RS25045 ec9928a33d4b8ef78fbe254523265b1d 375 Gene3D G3DSA:2.102.10.10 167 373 2.5E-40 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS25045 ec9928a33d4b8ef78fbe254523265b1d 375 SUPERFAMILY SSF50022 290 373 1.83E-24 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS25045 ec9928a33d4b8ef78fbe254523265b1d 375 Pfam PF00355 Rieske [2Fe-2S] domain 265 347 6.5E-11 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS12245 12c60ffeed1e24b6c89135b5a6a28b0e 594 SUPERFAMILY SSF75005 188 377 1.2E-16 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS12245 12c60ffeed1e24b6c89135b5a6a28b0e 594 Gene3D G3DSA:2.115.10.20 189 296 2.2E-12 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS03910 b96612cf5b61d1701b23676873c34911 313 Pfam PF04616 Glycosyl hydrolases family 43 30 310 2.2E-54 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_RS03910 b96612cf5b61d1701b23676873c34911 313 PIRSF PIRSF026534 6 313 1.9E-96 T 09-03-2017 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 UA74_RS03910 b96612cf5b61d1701b23676873c34911 313 SUPERFAMILY SSF75005 18 312 9.42E-72 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS03910 b96612cf5b61d1701b23676873c34911 313 Gene3D G3DSA:2.115.10.20 24 312 1.2E-80 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS29230 9b9aebb4a4ec976082d979c455aaa2fa 383 Gene3D G3DSA:3.20.20.70 21 264 6.6E-90 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS29230 9b9aebb4a4ec976082d979c455aaa2fa 383 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 09-03-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 UA74_RS29230 9b9aebb4a4ec976082d979c455aaa2fa 383 SUPERFAMILY SSF51395 23 334 3.11E-85 T 09-03-2017 UA74_RS29230 9b9aebb4a4ec976082d979c455aaa2fa 383 Gene3D G3DSA:1.10.1200.80 270 345 4.3E-18 T 09-03-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 UA74_RS29230 9b9aebb4a4ec976082d979c455aaa2fa 383 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 16 337 7.1E-118 T 09-03-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 UA74_RS29230 9b9aebb4a4ec976082d979c455aaa2fa 383 Pfam PF01207 Dihydrouridine synthase (Dus) 26 329 5.9E-106 T 09-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UA74_RS29230 9b9aebb4a4ec976082d979c455aaa2fa 383 PIRSF PIRSF006621 14 347 6.4E-112 T 09-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UA74_RS18445 67e0cbef34ec399ee4ba19ba149f2767 453 Pfam PF12770 CHAT domain 121 380 7.0E-7 T 09-03-2017 IPR024983 CHAT domain UA74_RS13780 94833cf0714d05ff324e09c6907e6f59 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.1E-5 T 09-03-2017 UA74_RS13780 94833cf0714d05ff324e09c6907e6f59 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.1E-5 T 09-03-2017 UA74_RS13780 94833cf0714d05ff324e09c6907e6f59 413 Gene3D G3DSA:3.50.50.60 2 159 5.6E-11 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS13780 94833cf0714d05ff324e09c6907e6f59 413 SUPERFAMILY SSF51905 283 357 1.42E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS13780 94833cf0714d05ff324e09c6907e6f59 413 SUPERFAMILY SSF51905 2 157 1.42E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS08590 ea8842152cccf5de1c6080e0d82665d9 418 Gene3D G3DSA:2.40.50.140 2 74 6.1E-23 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS08590 ea8842152cccf5de1c6080e0d82665d9 418 SUPERFAMILY SSF53335 65 412 7.97E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS08590 ea8842152cccf5de1c6080e0d82665d9 418 Pfam PF01938 TRAM domain 3 49 4.2E-10 T 09-03-2017 IPR002792 TRAM domain UA74_RS08590 ea8842152cccf5de1c6080e0d82665d9 418 Gene3D G3DSA:3.40.50.150 217 411 6.2E-39 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS08590 ea8842152cccf5de1c6080e0d82665d9 418 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 338 411 7.5E-9 T 09-03-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 UA74_RS08590 ea8842152cccf5de1c6080e0d82665d9 418 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 395 405 - T 09-03-2017 IPR030391 RNA methyltransferase TrmA, conserved site UA74_RS08590 ea8842152cccf5de1c6080e0d82665d9 418 SUPERFAMILY SSF50249 2 54 1.71E-11 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS17080 ed2938c80da191d5f3bcfb7cc12a7bb7 331 SUPERFAMILY SSF161098 109 310 2.62E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS17080 ed2938c80da191d5f3bcfb7cc12a7bb7 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 328 3.2E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS17080 ed2938c80da191d5f3bcfb7cc12a7bb7 331 Gene3D G3DSA:1.10.3720.10 106 319 4.6E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19370 77d6000f475512ad0e9737ce1819504d 319 Pfam PF07676 WD40-like Beta Propeller Repeat 125 140 0.0017 T 09-03-2017 IPR011659 WD40-like Beta Propeller UA74_RS19370 77d6000f475512ad0e9737ce1819504d 319 Gene3D G3DSA:2.130.10.10 127 319 1.5E-31 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS19370 77d6000f475512ad0e9737ce1819504d 319 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 227 308 1.2E-5 T 09-03-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 UA74_RS19370 77d6000f475512ad0e9737ce1819504d 319 SUPERFAMILY SSF69304 51 317 2.48E-22 T 09-03-2017 UA74_RS19370 77d6000f475512ad0e9737ce1819504d 319 Gene3D G3DSA:2.140.10.30 52 126 7.0E-4 T 09-03-2017 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 UA74_RS15205 c9914aafe84553f5aab1759c05e0d5c7 231 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 54 146 5.4E-16 T 09-03-2017 IPR026588 Choice-of-anchor A domain UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 105 1.1E-6 T 09-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 Pfam PF13244 Domain of unknown function (DUF4040) 606 670 1.0E-15 T 09-03-2017 IPR025383 Domain of unknown function DUF4040 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 Pfam PF00361 Proton-conducting membrane transporter 131 422 1.4E-67 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 4.9E-34 T 09-03-2017 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 4.9E-34 T 09-03-2017 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 108 128 4.9E-34 T 09-03-2017 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 4.9E-34 T 09-03-2017 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 266 4.9E-34 T 09-03-2017 UA74_RS27405 4dcc1b6b401c51a7b456b61c3b3f328e 850 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 4.9E-34 T 09-03-2017 UA74_RS28770 552ed7208ce8c47e27a111b7fdb657ad 807 Pfam PF02687 FtsX-like permease family 688 797 1.4E-6 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS28770 552ed7208ce8c47e27a111b7fdb657ad 807 Pfam PF02687 FtsX-like permease family 206 321 1.1E-7 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS06495 429e3660e4c6bb721e1e08716a93f1ed 250 SUPERFAMILY SSF53335 26 195 2.48E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS06495 429e3660e4c6bb721e1e08716a93f1ed 250 Pfam PF08241 Methyltransferase domain 48 138 1.5E-18 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS06495 429e3660e4c6bb721e1e08716a93f1ed 250 Gene3D G3DSA:3.40.50.150 34 191 1.6E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19255 53e2f0e31593aff6be27568d204f7222 131 Pfam PF01899 Na+/H+ ion antiporter subunit 5 108 1.1E-26 T 09-03-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 UA74_RS04735 e4f4b3ecb9db67737b6613cb393dff1d 295 SUPERFAMILY SSF53474 39 289 1.54E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS04735 e4f4b3ecb9db67737b6613cb393dff1d 295 Pfam PF12697 Alpha/beta hydrolase family 43 282 2.2E-17 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS04735 e4f4b3ecb9db67737b6613cb393dff1d 295 Gene3D G3DSA:3.40.50.1820 24 290 2.1E-34 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS29900 282d96d53ed64e866c84bb828ee119ab 377 SUPERFAMILY SSF81345 33 368 1.7E-83 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS29900 282d96d53ed64e866c84bb828ee119ab 377 Gene3D G3DSA:1.10.3470.10 41 372 6.2E-108 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS29900 282d96d53ed64e866c84bb828ee119ab 377 Pfam PF01032 FecCD transport family 49 368 2.9E-94 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS06450 5f014d25bea37b14b1684d305da39684 171 Gene3D G3DSA:3.30.1310.10 17 115 3.0E-9 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS06450 5f014d25bea37b14b1684d305da39684 171 SUPERFAMILY SSF82607 24 112 1.7E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS06450 5f014d25bea37b14b1684d305da39684 171 Pfam PF02575 YbaB/EbfC DNA-binding family 28 112 7.7E-11 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS06725 c219ad4eb39adbbec199202078e52ecc 230 Gene3D G3DSA:3.40.50.880 7 205 2.1E-66 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS06725 c219ad4eb39adbbec199202078e52ecc 230 SUPERFAMILY SSF52317 5 187 2.29E-53 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS06725 c219ad4eb39adbbec199202078e52ecc 230 Pfam PF01965 DJ-1/PfpI family 7 166 4.4E-31 T 09-03-2017 IPR002818 DJ-1/PfpI UA74_RS20425 32e68d7266a62c41d87f2bc2c4ba06e1 202 SUPERFAMILY SSF48498 79 193 2.86E-22 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS20425 32e68d7266a62c41d87f2bc2c4ba06e1 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 3.5E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS20425 32e68d7266a62c41d87f2bc2c4ba06e1 202 SUPERFAMILY SSF46689 3 76 2.74E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20425 32e68d7266a62c41d87f2bc2c4ba06e1 202 Gene3D G3DSA:1.10.10.60 3 66 3.1E-21 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20425 32e68d7266a62c41d87f2bc2c4ba06e1 202 Gene3D G3DSA:1.10.357.10 74 193 2.3E-31 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 SUPERFAMILY SSF53850 91 291 3.72E-31 T 09-03-2017 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 Pfam PF03466 LysR substrate binding domain 88 290 2.9E-34 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 Gene3D G3DSA:3.40.190.10 174 261 2.2E-19 T 09-03-2017 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.7E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.7E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.7E-8 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 Gene3D G3DSA:1.10.10.10 2 85 6.9E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.6E-23 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 Gene3D G3DSA:3.40.190.10 90 173 1.1E-14 T 09-03-2017 UA74_RS15485 7daeb9179592814031da0ae3d5031ce1 310 SUPERFAMILY SSF46785 2 112 1.59E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00150 057e2b8b9853d31f67aea601035671c3 399 SUPERFAMILY SSF49879 271 396 3.63E-29 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 UA74_RS00150 057e2b8b9853d31f67aea601035671c3 399 Pfam PF00498 FHA domain 327 389 1.0E-16 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS00150 057e2b8b9853d31f67aea601035671c3 399 Gene3D G3DSA:2.60.200.20 299 396 3.8E-26 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS00150 057e2b8b9853d31f67aea601035671c3 399 SMART SM00240 325 375 4.9E-13 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS00150 057e2b8b9853d31f67aea601035671c3 399 Pfam PF12401 Protein of unknown function (DUF2662) 4 117 7.0E-43 T 09-03-2017 IPR022128 Protein of unknown function DUF3662 UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 SUPERFAMILY SSF46785 24 107 2.56E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 5.6E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 5.6E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 5.6E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 5.6E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 Pfam PF01022 Bacterial regulatory protein, arsR family 42 86 5.7E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 SMART SM00418 34 112 3.2E-28 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS24510 176dea8a58fee769fc1ac11696d75e4b 126 Gene3D G3DSA:1.10.10.10 23 118 1.2E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23700 38bf5c50bebdc89b45f82b23206153dc 264 Pfam PF04248 Domain of unknown function (DUF427) 41 131 7.9E-29 T 09-03-2017 IPR007361 Domain of unknown function DUF427 UA74_RS23700 38bf5c50bebdc89b45f82b23206153dc 264 Pfam PF04248 Domain of unknown function (DUF427) 164 254 9.0E-28 T 09-03-2017 IPR007361 Domain of unknown function DUF427 UA74_RS25675 cc9c90deb99f288c5df09c39879df5bd 418 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 4 383 32.553 T 09-03-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 UA74_RS25675 cc9c90deb99f288c5df09c39879df5bd 418 Gene3D G3DSA:3.30.420.40 5 211 3.4E-49 T 09-03-2017 UA74_RS25675 cc9c90deb99f288c5df09c39879df5bd 418 SUPERFAMILY SSF53067 100 113 2.22E-8 T 09-03-2017 UA74_RS25675 cc9c90deb99f288c5df09c39879df5bd 418 SUPERFAMILY SSF53067 152 334 2.22E-8 T 09-03-2017 UA74_RS25675 cc9c90deb99f288c5df09c39879df5bd 418 Pfam PF03702 Uncharacterised protein family (UPF0075) 5 382 6.6E-94 T 09-03-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 UA74_RS25590 3d9853f2b4f0b45d7edc21e06d110545 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 15 327 58.231 T 09-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS25590 3d9853f2b4f0b45d7edc21e06d110545 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 120 196 4.5E-27 T 09-03-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS25590 3d9853f2b4f0b45d7edc21e06d110545 328 Gene3D G3DSA:3.40.47.10 175 325 5.2E-43 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS25590 3d9853f2b4f0b45d7edc21e06d110545 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 16 325 2.3E-97 T 09-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS25590 3d9853f2b4f0b45d7edc21e06d110545 328 SUPERFAMILY SSF53901 15 326 8.86E-60 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS25590 3d9853f2b4f0b45d7edc21e06d110545 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 235 325 3.2E-29 T 09-03-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_RS25590 3d9853f2b4f0b45d7edc21e06d110545 328 Gene3D G3DSA:3.40.47.10 16 174 2.4E-55 T 09-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 UA74_RS19420 2613d955345e734fe03f0940e59771ad 145 SUPERFAMILY SSF82784 1 136 6.41E-30 T 09-03-2017 IPR003718 OsmC/Ohr family UA74_RS19420 2613d955345e734fe03f0940e59771ad 145 Pfam PF02566 OsmC-like protein 45 140 8.0E-16 T 09-03-2017 IPR003718 OsmC/Ohr family UA74_RS19420 2613d955345e734fe03f0940e59771ad 145 Gene3D G3DSA:3.30.300.20 3 144 5.0E-43 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS19420 2613d955345e734fe03f0940e59771ad 145 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 142 3.4E-49 T 09-03-2017 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 SUPERFAMILY SSF46785 24 115 8.06E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 Pfam PF01022 Bacterial regulatory protein, arsR family 43 91 1.2E-15 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 SMART SM00418 36 116 8.3E-30 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 09-03-2017 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 Gene3D G3DSA:1.10.10.10 17 115 1.2E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 2.2E-20 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 2.2E-20 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 2.2E-20 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS19585 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 2.2E-20 T 09-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_RS16050 f0a172c290948af2b35977b5701cef13 295 Pfam PF01636 Phosphotransferase enzyme family 25 232 8.7E-11 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS16050 f0a172c290948af2b35977b5701cef13 295 Gene3D G3DSA:3.90.1200.10 104 230 1.3E-4 T 09-03-2017 UA74_RS16050 f0a172c290948af2b35977b5701cef13 295 SUPERFAMILY SSF56112 23 266 4.08E-19 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS24845 62b33864d6e6b7aee59303bcee58ad14 291 SUPERFAMILY SSF51695 38 288 4.71E-72 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS24845 62b33864d6e6b7aee59303bcee58ad14 291 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 44 282 9.6E-46 T 09-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_RS24845 62b33864d6e6b7aee59303bcee58ad14 291 Gene3D G3DSA:3.20.20.190 27 289 1.6E-75 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS25425 dbef7d3ea22d7a1c290f1eda876dd0d6 344 Gene3D G3DSA:3.40.640.10 25 239 2.0E-47 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS25425 dbef7d3ea22d7a1c290f1eda876dd0d6 344 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 193 206 - T 09-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_RS25425 dbef7d3ea22d7a1c290f1eda876dd0d6 344 SUPERFAMILY SSF53383 10 335 3.33E-55 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS25425 dbef7d3ea22d7a1c290f1eda876dd0d6 344 Gene3D G3DSA:3.90.1150.10 241 339 1.4E-18 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS25425 dbef7d3ea22d7a1c290f1eda876dd0d6 344 Pfam PF00155 Aminotransferase class I and II 35 334 7.1E-24 T 09-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_RS27825 822d68dea697615a36915487e1bf0027 552 Pfam PF00817 impB/mucB/samB family 7 136 1.7E-15 T 09-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_RS27825 822d68dea697615a36915487e1bf0027 552 SUPERFAMILY SSF56672 10 217 1.42E-33 T 09-03-2017 UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 Gene3D G3DSA:3.40.50.720 7 240 4.7E-67 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.9E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 9.9E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.9E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 Pfam PF00106 short chain dehydrogenase 8 203 1.9E-46 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13760 f4abf4a992a9e51e45efaf31e9907253 241 SUPERFAMILY SSF51735 7 233 4.48E-58 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22340 8598e9e6ce669e9782e29efec67f1453 172 SMART SM00347 25 124 6.2E-4 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS22340 8598e9e6ce669e9782e29efec67f1453 172 SUPERFAMILY SSF46785 6 138 1.36E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22340 8598e9e6ce669e9782e29efec67f1453 172 Gene3D G3DSA:1.10.10.10 6 140 6.4E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22340 8598e9e6ce669e9782e29efec67f1453 172 Pfam PF13463 Winged helix DNA-binding domain 33 97 7.3E-7 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS22340 8598e9e6ce669e9782e29efec67f1453 172 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 97 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_RS05950 d0a9dc9ef588325ca48e1dc18058430c 197 SUPERFAMILY SSF48498 81 182 3.34E-14 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS05950 d0a9dc9ef588325ca48e1dc18058430c 197 Gene3D G3DSA:1.10.357.10 9 189 5.0E-37 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS05950 d0a9dc9ef588325ca48e1dc18058430c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.8E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05950 d0a9dc9ef588325ca48e1dc18058430c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.8E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05950 d0a9dc9ef588325ca48e1dc18058430c 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 2.8E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS05950 d0a9dc9ef588325ca48e1dc18058430c 197 SUPERFAMILY SSF46689 9 87 5.99E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS13270 558b13d7bb7b9cca89bbac3d315c6d97 172 SUPERFAMILY SSF53271 8 159 3.02E-40 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS13270 558b13d7bb7b9cca89bbac3d315c6d97 172 Pfam PF00156 Phosphoribosyl transferase domain 37 145 3.8E-15 T 09-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_RS13270 558b13d7bb7b9cca89bbac3d315c6d97 172 Gene3D G3DSA:3.40.50.2020 2 167 3.7E-49 T 09-03-2017 IPR029057 Phosphoribosyltransferase-like UA74_RS13270 558b13d7bb7b9cca89bbac3d315c6d97 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 1 167 30.456 T 09-03-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 UA74_RS14640 9bc5f75d66e47c22cf220ec2be09b175 318 SUPERFAMILY SSF54593 5 282 1.98E-49 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14640 9bc5f75d66e47c22cf220ec2be09b175 318 Gene3D G3DSA:3.10.180.10 2 131 4.3E-36 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14640 9bc5f75d66e47c22cf220ec2be09b175 318 Gene3D G3DSA:3.10.180.10 140 311 3.2E-46 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14640 9bc5f75d66e47c22cf220ec2be09b175 318 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 270 4.4E-12 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS14640 9bc5f75d66e47c22cf220ec2be09b175 318 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 127 1.5E-13 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS21205 1eab5d7f588c12003da7f041d8400704 415 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 58 179 2.1E-8 T 09-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain UA74_RS21205 1eab5d7f588c12003da7f041d8400704 415 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 251 366 1.1E-17 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS21205 1eab5d7f588c12003da7f041d8400704 415 SUPERFAMILY SSF90002 251 313 2.88E-10 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS21205 1eab5d7f588c12003da7f041d8400704 415 SUPERFAMILY SSF90002 340 366 2.88E-10 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS21205 1eab5d7f588c12003da7f041d8400704 415 SMART SM00833 250 366 5.5E-36 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS21205 1eab5d7f588c12003da7f041d8400704 415 Gene3D G3DSA:3.40.50.300 33 206 8.4E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21205 1eab5d7f588c12003da7f041d8400704 415 Gene3D G3DSA:3.30.1220.10 246 366 1.6E-8 T 09-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_RS00650 247735f568a2dba8baf1889bf591bf45 294 Gene3D G3DSA:3.90.550.10 3 248 7.8E-34 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00650 247735f568a2dba8baf1889bf591bf45 294 Pfam PF00535 Glycosyl transferase family 2 5 123 1.6E-15 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS00650 247735f568a2dba8baf1889bf591bf45 294 SUPERFAMILY SSF53448 3 236 6.49E-31 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS24015 bfa5485b1f37b32804cb97176627b679 265 Pfam PF03211 Pectate lyase 44 237 3.5E-73 T 09-03-2017 IPR004898 Pectate lyase, catalytic GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 UA74_RS24015 bfa5485b1f37b32804cb97176627b679 265 SUPERFAMILY SSF51126 48 220 2.28E-51 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS24015 bfa5485b1f37b32804cb97176627b679 265 Gene3D G3DSA:2.160.20.10 51 264 4.6E-81 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 Pfam PF01494 FAD binding domain 3 349 1.4E-72 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 6.3E-33 T 09-03-2017 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 6.3E-33 T 09-03-2017 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 6.3E-33 T 09-03-2017 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 6.3E-33 T 09-03-2017 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 338 6.3E-33 T 09-03-2017 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 Gene3D G3DSA:3.50.50.60 276 355 8.3E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 Gene3D G3DSA:3.50.50.60 3 176 8.3E-52 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 SUPERFAMILY SSF51905 3 171 7.86E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15155 67d3353f21f041fe11e775ac83c57f45 521 SUPERFAMILY SSF51905 275 384 7.86E-60 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11750 bc5004248537075ae69a7675df17058d 440 SUPERFAMILY SSF53300 49 226 3.5E-22 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS11750 bc5004248537075ae69a7675df17058d 440 Pfam PF13768 von Willebrand factor type A domain 51 208 1.2E-13 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS11750 bc5004248537075ae69a7675df17058d 440 SMART SM00327 48 219 3.3E-13 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS11750 bc5004248537075ae69a7675df17058d 440 Gene3D G3DSA:3.40.50.410 50 204 5.8E-11 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 35 41 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 32 44 2.6E-20 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 66 85 2.6E-20 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 270 292 2.6E-20 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 293 307 2.6E-20 T 09-03-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 SUPERFAMILY SSF53335 3 192 3.03E-68 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 SUPERFAMILY SSF53335 241 335 3.03E-68 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 Pfam PF01555 DNA methylase 32 327 3.0E-46 T 09-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 Gene3D G3DSA:3.40.50.150 2 164 1.5E-68 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05080 3327854fae5f0cc3af33af73b6363a61 475 Gene3D G3DSA:3.40.50.150 225 362 1.5E-68 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS07235 0fa98d9f99680fa2d3949088c3e8c7e7 174 Gene3D G3DSA:3.90.79.10 2 172 6.8E-37 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS07235 0fa98d9f99680fa2d3949088c3e8c7e7 174 Pfam PF00293 NUDIX domain 43 152 9.7E-10 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS07235 0fa98d9f99680fa2d3949088c3e8c7e7 174 SUPERFAMILY SSF55811 2 173 5.69E-34 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS09170 b7da3b9aeb1527862590fd4a925fdaea 178 SUPERFAMILY SSF49777 7 170 1.44E-44 T 09-03-2017 IPR008914 Phosphatidylethanolamine-binding protein UA74_RS09170 b7da3b9aeb1527862590fd4a925fdaea 178 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 43 175 2.0E-37 T 09-03-2017 IPR005247 YbhB/YbcL UA74_RS09170 b7da3b9aeb1527862590fd4a925fdaea 178 Pfam PF01161 Phosphatidylethanolamine-binding protein 34 174 1.9E-32 T 09-03-2017 IPR008914 Phosphatidylethanolamine-binding protein UA74_RS09170 b7da3b9aeb1527862590fd4a925fdaea 178 Gene3D G3DSA:3.90.280.10 20 177 3.8E-47 T 09-03-2017 IPR008914 Phosphatidylethanolamine-binding protein UA74_RS29110 719fbb09dfe111ea6255e698bc4be872 314 Gene3D G3DSA:3.40.50.1820 3 304 1.8E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS29110 719fbb09dfe111ea6255e698bc4be872 314 SUPERFAMILY SSF53474 8 304 4.73E-36 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS29110 719fbb09dfe111ea6255e698bc4be872 314 Pfam PF12697 Alpha/beta hydrolase family 29 297 1.7E-20 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS20185 a752a5a69762bf936a88ea4ef47f8a7b 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 1.2E-11 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS20185 a752a5a69762bf936a88ea4ef47f8a7b 130 SUPERFAMILY SSF54593 7 123 2.15E-24 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS20185 a752a5a69762bf936a88ea4ef47f8a7b 130 Gene3D G3DSA:3.10.180.10 3 123 3.6E-28 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS13305 2466d29a9c88dd9e9d92380783f4f375 562 Pfam PF00005 ABC transporter 345 491 3.0E-17 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS13305 2466d29a9c88dd9e9d92380783f4f375 562 SUPERFAMILY SSF90123 8 321 1.83E-37 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13305 2466d29a9c88dd9e9d92380783f4f375 562 SMART SM00382 354 537 7.1E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS13305 2466d29a9c88dd9e9d92380783f4f375 562 Gene3D G3DSA:1.20.1560.10 10 317 4.4E-34 T 09-03-2017 UA74_RS13305 2466d29a9c88dd9e9d92380783f4f375 562 SUPERFAMILY SSF52540 324 551 8.63E-50 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13305 2466d29a9c88dd9e9d92380783f4f375 562 Pfam PF00664 ABC transporter transmembrane region 29 282 7.7E-10 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS13305 2466d29a9c88dd9e9d92380783f4f375 562 Gene3D G3DSA:3.40.50.300 329 552 1.4E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01805 f2085202eb2fb7894c1aafe4468d40f1 181 SUPERFAMILY SSF55729 14 138 1.92E-18 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS01805 f2085202eb2fb7894c1aafe4468d40f1 181 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 21 174 1.7E-54 T 09-03-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 UA74_RS01805 f2085202eb2fb7894c1aafe4468d40f1 181 Pfam PF00583 Acetyltransferase (GNAT) family 66 138 2.1E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS01805 f2085202eb2fb7894c1aafe4468d40f1 181 Gene3D G3DSA:3.40.630.30 20 174 1.6E-61 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS27870 b37599f45f0c9b52a9f34a0f976eb930 135 SUPERFAMILY SSF52242 3 131 1.44E-49 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS27870 b37599f45f0c9b52a9f34a0f976eb930 135 Gene3D G3DSA:3.40.50.280 3 131 9.6E-55 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS27870 b37599f45f0c9b52a9f34a0f976eb930 135 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 4 132 2.2E-50 T 09-03-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS27870 b37599f45f0c9b52a9f34a0f976eb930 135 Pfam PF02310 B12 binding domain 5 115 3.1E-23 T 09-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_RS08910 c753574bcc4b00b3a59f785fc0a890c7 372 Pfam PF01979 Amidohydrolase family 160 349 4.1E-10 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS08910 c753574bcc4b00b3a59f785fc0a890c7 372 Gene3D G3DSA:2.30.40.10 319 356 3.9E-6 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS08910 c753574bcc4b00b3a59f785fc0a890c7 372 Gene3D G3DSA:2.30.40.10 33 43 3.9E-6 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS08910 c753574bcc4b00b3a59f785fc0a890c7 372 Gene3D G3DSA:3.20.20.140 44 318 2.0E-61 T 09-03-2017 UA74_RS08910 c753574bcc4b00b3a59f785fc0a890c7 372 SUPERFAMILY SSF51556 42 321 7.23E-60 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS15455 ddfc8b37e900bebad7af210f9256e40c 107 Gene3D G3DSA:1.20.5.40 28 47 1.8E-4 T 09-03-2017 UA74_RS23520 6f5b3f3997846ab0845697aa2e9b4bf4 452 PIRSF PIRSF017901 3 451 3.9E-95 T 09-03-2017 UA74_RS23520 6f5b3f3997846ab0845697aa2e9b4bf4 452 SUPERFAMILY SSF55931 302 436 6.77E-44 T 09-03-2017 UA74_RS23520 6f5b3f3997846ab0845697aa2e9b4bf4 452 SUPERFAMILY SSF55931 23 264 6.77E-44 T 09-03-2017 UA74_RS23520 6f5b3f3997846ab0845697aa2e9b4bf4 452 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 76 354 1.6E-42 T 09-03-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 296 494 2.5E-67 T 09-03-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 SUPERFAMILY SSF47203 277 498 2.3E-51 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 22 286 3.4E-93 T 09-03-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 Gene3D G3DSA:2.40.110.10 159 278 2.9E-45 T 09-03-2017 UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 PIRSF PIRSF500125 7 522 1.6E-256 T 09-03-2017 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 PIRSF PIRSF000331 18 506 3.4E-201 T 09-03-2017 IPR004925 HpaB/PvcC/4-BUDH UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 Gene3D G3DSA:1.10.3140.10 19 158 1.2E-55 T 09-03-2017 UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 Gene3D G3DSA:1.20.140.10 279 480 7.6E-36 T 09-03-2017 UA74_RS17630 6ae9fe243155fd5acddab74a5366af61 527 SUPERFAMILY SSF56645 20 287 1.28E-79 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS10695 a3896000775a43a362cdf6076684da4e 237 SUPERFAMILY SSF52540 3 233 1.96E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10695 a3896000775a43a362cdf6076684da4e 237 PIRSF PIRSF039137 1 237 5.5E-110 T 09-03-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 UA74_RS10695 a3896000775a43a362cdf6076684da4e 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS10695 a3896000775a43a362cdf6076684da4e 237 SMART SM00382 28 215 3.5E-10 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10695 a3896000775a43a362cdf6076684da4e 237 Gene3D G3DSA:3.40.50.300 2 233 3.4E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10695 a3896000775a43a362cdf6076684da4e 237 Pfam PF00005 ABC transporter 19 164 3.9E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS07735 d14d68d53821dc94a906a3a09cb999bb 482 SUPERFAMILY SSF81606 5 236 3.53E-59 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS07735 d14d68d53821dc94a906a3a09cb999bb 482 SMART SM00331 11 236 1.2E-36 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS07735 d14d68d53821dc94a906a3a09cb999bb 482 Pfam PF13672 Protein phosphatase 2C 19 196 1.3E-10 T 09-03-2017 UA74_RS07735 d14d68d53821dc94a906a3a09cb999bb 482 Gene3D G3DSA:3.60.40.10 2 236 3.4E-62 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS07735 d14d68d53821dc94a906a3a09cb999bb 482 SMART SM00332 2 234 5.7E-23 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF51445 292 635 5.76E-103 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 Gene3D G3DSA:2.60.40.320 191 294 4.6E-15 T 09-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF49785 2 187 1.98E-52 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 Pfam PF00703 Glycosyl hydrolases family 2 205 295 1.9E-5 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 Gene3D G3DSA:3.20.20.80 295 531 8.5E-63 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 Gene3D G3DSA:3.20.20.80 569 636 8.5E-63 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 Gene3D G3DSA:2.60.120.260 18 187 4.4E-26 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF49303 191 295 7.91E-17 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 UA74_RS08995 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF49303 732 799 5.61E-5 T 09-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 Gene3D G3DSA:3.40.250.10 151 281 6.3E-34 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 Gene3D G3DSA:3.40.250.10 2 145 1.1E-46 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 SUPERFAMILY SSF52821 164 277 7.6E-29 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 ProSitePatterns PS00683 Rhodanese C-terminal signature. 258 268 - T 09-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 SMART SM00450 151 274 1.3E-14 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 SMART SM00450 6 130 9.1E-23 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 SUPERFAMILY SSF52821 2 145 5.11E-38 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 Pfam PF00581 Rhodanese-like domain 163 269 2.0E-9 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS08835 11ea9b7265358e04873da069993db9d8 283 Pfam PF00581 Rhodanese-like domain 7 126 2.3E-17 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS26980 e303d46fd0332f12f0a0226841c64a7c 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 148 28.127 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_RS26980 e303d46fd0332f12f0a0226841c64a7c 162 Gene3D G3DSA:3.40.50.7700 1 145 2.7E-66 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_RS26980 e303d46fd0332f12f0a0226841c64a7c 162 Pfam PF00731 AIR carboxylase 1 138 1.9E-60 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_RS26980 e303d46fd0332f12f0a0226841c64a7c 162 SUPERFAMILY SSF52255 1 144 1.96E-59 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_RS26980 e303d46fd0332f12f0a0226841c64a7c 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 144 2.0E-59 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_RS26980 e303d46fd0332f12f0a0226841c64a7c 162 PIRSF PIRSF001338 1 159 9.0E-62 T 09-03-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 UA74_RS26980 e303d46fd0332f12f0a0226841c64a7c 162 SMART SM01001 1 144 4.4E-80 T 09-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_RS05865 7767465e745ef1da0e4c616a6f647c0e 312 SMART SM00382 29 239 3.0E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS05865 7767465e745ef1da0e4c616a6f647c0e 312 Pfam PF00005 ABC transporter 21 163 1.0E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS05865 7767465e745ef1da0e4c616a6f647c0e 312 SUPERFAMILY SSF52540 3 227 1.7E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05865 7767465e745ef1da0e4c616a6f647c0e 312 Gene3D G3DSA:3.40.50.300 2 230 6.9E-74 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05865 7767465e745ef1da0e4c616a6f647c0e 312 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS25545 5fc982143be9770d3ba98f7e136a3cb3 66 Pfam PF04149 Domain of unknown function (DUF397) 6 58 4.4E-19 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS27520 e5b951f516cf434dca2db35f43ffae63 136 Gene3D G3DSA:1.10.10.10 8 135 3.2E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27520 e5b951f516cf434dca2db35f43ffae63 136 SUPERFAMILY SSF46785 7 135 1.58E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16185 dbf652c110cbbc2a1c7f8e396d81b155 227 Pfam PF08666 SAF domain 67 128 2.3E-4 T 09-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_RS14540 de9c0ff3a1b87c7a994409b20ca2eab2 346 Pfam PF01032 FecCD transport family 35 339 3.6E-65 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS14540 de9c0ff3a1b87c7a994409b20ca2eab2 346 Gene3D G3DSA:1.10.3470.10 21 343 7.6E-72 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS14540 de9c0ff3a1b87c7a994409b20ca2eab2 346 SUPERFAMILY SSF81345 17 339 1.57E-55 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 09-03-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 09-03-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 SUPERFAMILY SSF53681 7 109 1.31E-32 T 09-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 255 3.5E-66 T 09-03-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 Hamap MF_00258 Glutamate racemase [murI]. 6 259 36.156 T 09-03-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 SUPERFAMILY SSF53681 111 258 1.26E-38 T 09-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 Gene3D G3DSA:3.40.50.1860 5 174 9.0E-52 T 09-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS06330 ac59cd4f8840eaa3c1e55c3fec93a237 261 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 1.4E-31 T 09-03-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_RS28525 82880b4d50cea5f6d283b3833e519957 147 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 16 121 2.0E-6 T 09-03-2017 IPR024495 Protein of unknown function DUF2771 UA74_RS28525 82880b4d50cea5f6d283b3833e519957 147 Pfam PF10969 Protein of unknown function (DUF2771) 12 127 4.0E-20 T 09-03-2017 IPR024495 Protein of unknown function DUF2771 UA74_RS08365 e78ece1d38a5569dc8899fbc7fff241b 290 Gene3D G3DSA:3.40.50.1110 20 108 4.6E-9 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS08365 e78ece1d38a5569dc8899fbc7fff241b 290 Gene3D G3DSA:3.40.50.1110 147 249 4.6E-9 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS08365 e78ece1d38a5569dc8899fbc7fff241b 290 SUPERFAMILY SSF52266 149 250 2.0E-11 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS08365 e78ece1d38a5569dc8899fbc7fff241b 290 SUPERFAMILY SSF52266 22 109 2.0E-11 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS08365 e78ece1d38a5569dc8899fbc7fff241b 290 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 25 233 2.5E-6 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS11035 ef0d5ffe1342e6a55a62d4f7aea0cc6b 129 Pfam PF04486 SchA/CurD like domain 1 119 3.9E-49 T 09-03-2017 IPR007575 SchA/CurD-like domain UA74_RS20605 d13083ba01de88b1253a8ba81f8fbaa0 362 SUPERFAMILY SSF51695 56 243 6.07E-9 T 09-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 UA74_RS20605 d13083ba01de88b1253a8ba81f8fbaa0 362 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 124 217 3.5E-8 T 09-03-2017 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent UA74_RS09595 d000215d84f236a5eb79c052f255e249 124 Pfam PF13707 RloB-like protein 43 121 2.5E-11 T 09-03-2017 IPR025591 RloB-like protein UA74_RS28655 44f273a2cbfb19ce62f388d57669e867 285 Gene3D G3DSA:1.10.3720.10 71 267 9.5E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS28655 44f273a2cbfb19ce62f388d57669e867 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 263 3.2E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS28655 44f273a2cbfb19ce62f388d57669e867 285 SUPERFAMILY SSF161098 75 257 1.44E-23 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03010 13160b260407aa8d12796cb0c71cf058 136 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 25 136 1.8E-40 T 09-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS03010 13160b260407aa8d12796cb0c71cf058 136 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 23 136 5.9E-48 T 09-03-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03010 13160b260407aa8d12796cb0c71cf058 136 Gene3D G3DSA:3.30.420.100 41 136 2.7E-37 T 09-03-2017 UA74_RS03010 13160b260407aa8d12796cb0c71cf058 136 SUPERFAMILY SSF53137 23 134 5.01E-48 T 09-03-2017 UA74_RS03010 13160b260407aa8d12796cb0c71cf058 136 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 22 136 28.079 T 09-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS24785 52900cf52f67b7b62d1f93e844169212 225 Pfam PF11353 Protein of unknown function (DUF3153) 20 212 5.9E-11 T 09-03-2017 IPR021499 Protein of unknown function DUF3153 UA74_RS21495 dcfb1dbf04987edcb2a2075e00c2ffc5 512 SUPERFAMILY SSF53720 3 487 2.88E-131 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS21495 dcfb1dbf04987edcb2a2075e00c2ffc5 512 Gene3D G3DSA:3.40.605.10 4 262 4.6E-75 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS21495 dcfb1dbf04987edcb2a2075e00c2ffc5 512 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS21495 dcfb1dbf04987edcb2a2075e00c2ffc5 512 Gene3D G3DSA:3.40.309.10 263 460 1.2E-53 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS21495 dcfb1dbf04987edcb2a2075e00c2ffc5 512 Pfam PF00171 Aldehyde dehydrogenase family 19 485 1.4E-127 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS27400 a802668acac3429576bbe1fae0eae7d8 181 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 37 158 1.8E-28 T 09-03-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 Gene3D G3DSA:3.30.300.50 51 129 2.2E-20 T 09-03-2017 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 Gene3D G3DSA:4.10.1080.10 431 470 8.7E-4 T 09-03-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 384 398 2.3E-6 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 247 261 2.3E-6 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 337 354 2.3E-6 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 316 336 2.3E-6 T 09-03-2017 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 369 380 - T 09-03-2017 IPR033116 Serine proteases, trypsin family, serine active site UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 Gene3D G3DSA:2.40.10.10 314 415 8.3E-16 T 09-03-2017 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 SUPERFAMILY SSF50494 231 393 8.71E-22 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 Pfam PF00089 Trypsin 249 395 1.1E-5 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 681 713 0.0012 T 09-03-2017 IPR019931 LPXTG cell wall anchor domain UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 Gene3D G3DSA:2.60.40.1560 479 527 3.9E-4 T 09-03-2017 UA74_RS01625 c65450697a5748ee08f1d246c0372ab7 724 Gene3D G3DSA:2.40.10.10 215 313 2.5E-12 T 09-03-2017 UA74_RS21615 898734bf44c0b16288369d549f4d9101 356 Gene3D G3DSA:3.40.50.1000 17 93 3.3E-33 T 09-03-2017 IPR023214 HAD-like domain UA74_RS21615 898734bf44c0b16288369d549f4d9101 356 Gene3D G3DSA:3.40.50.1000 203 278 3.3E-33 T 09-03-2017 IPR023214 HAD-like domain UA74_RS21615 898734bf44c0b16288369d549f4d9101 356 Pfam PF13344 Haloacid dehalogenase-like hydrolase 24 124 8.2E-19 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_RS21615 898734bf44c0b16288369d549f4d9101 356 SUPERFAMILY SSF56784 20 276 1.76E-52 T 09-03-2017 IPR023214 HAD-like domain UA74_RS21615 898734bf44c0b16288369d549f4d9101 356 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 25 251 1.8E-31 T 09-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_RS21615 898734bf44c0b16288369d549f4d9101 356 Gene3D G3DSA:3.40.50.10410 94 202 1.0E-26 T 09-03-2017 IPR023215 Nitrophenylphosphatase-like domain UA74_RS21615 898734bf44c0b16288369d549f4d9101 356 Pfam PF13242 HAD-hyrolase-like 204 275 8.9E-15 T 09-03-2017 UA74_RS08540 3ae73835e0afe13d4fe11d9f5f1f6d08 225 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 80 170 3.6E-10 T 09-03-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_RS27195 579723d072477271e6c7ab8982a09f4a 150 Gene3D G3DSA:3.10.490.10 3 147 4.5E-47 T 09-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like UA74_RS27195 579723d072477271e6c7ab8982a09f4a 150 Pfam PF13772 AIG2-like family 59 140 1.8E-21 T 09-03-2017 UA74_RS27195 579723d072477271e6c7ab8982a09f4a 150 SUPERFAMILY SSF110857 3 120 8.37E-17 T 09-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 Gene3D G3DSA:3.40.50.300 245 455 1.0E-47 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 Pfam PF00005 ABC transporter 266 412 4.4E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 Pfam PF00005 ABC transporter 20 175 2.1E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 Gene3D G3DSA:3.40.50.300 3 226 3.9E-48 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 ProSitePatterns PS00211 ABC transporters family signature. 384 398 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 SMART SM00382 28 211 8.3E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 SMART SM00382 271 460 7.0E-16 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 SUPERFAMILY SSF52540 241 459 1.26E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16660 ceb38acf74600cb76f1e5219874fbe85 462 SUPERFAMILY SSF52540 3 225 1.02E-44 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12985 4a7a6ece0acf3131b6a84e1639036962 281 Pfam PF00227 Proteasome subunit 52 235 4.7E-33 T 09-03-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 UA74_RS12985 4a7a6ece0acf3131b6a84e1639036962 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 275 1.6E-101 T 09-03-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UA74_RS12985 4a7a6ece0acf3131b6a84e1639036962 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 10 281 47.352 T 09-03-2017 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UA74_RS12985 4a7a6ece0acf3131b6a84e1639036962 281 Gene3D G3DSA:3.60.20.10 54 259 3.9E-51 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS12985 4a7a6ece0acf3131b6a84e1639036962 281 SUPERFAMILY SSF56235 51 265 2.04E-51 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS02280 e8dad0b0f4a802922e8422d236cd605a 80 SUPERFAMILY SSF52833 2 79 9.1E-16 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS02280 e8dad0b0f4a802922e8422d236cd605a 80 Gene3D G3DSA:3.40.30.10 5 80 3.9E-21 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS02280 e8dad0b0f4a802922e8422d236cd605a 80 Pfam PF05768 Glutaredoxin-like domain (DUF836) 6 78 6.2E-13 T 09-03-2017 IPR008554 Glutaredoxin-like UA74_RS11385 1416e4f0319b375a04beb38cdc021493 317 SUPERFAMILY SSF52540 3 224 1.95E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11385 1416e4f0319b375a04beb38cdc021493 317 SMART SM00382 29 211 8.9E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS11385 1416e4f0319b375a04beb38cdc021493 317 Pfam PF00005 ABC transporter 20 163 9.8E-26 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS11385 1416e4f0319b375a04beb38cdc021493 317 Pfam PF13732 Domain of unknown function (DUF4162) 217 304 6.5E-7 T 09-03-2017 IPR025302 Domain of unknown function DUF4162 UA74_RS11385 1416e4f0319b375a04beb38cdc021493 317 Gene3D G3DSA:3.40.50.300 2 224 2.8E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11385 1416e4f0319b375a04beb38cdc021493 317 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS11385 1416e4f0319b375a04beb38cdc021493 317 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 305 2.2E-102 T 09-03-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_RS00025 8231fcaa35ce24dff740b73887e9904a 181 Hamap MF_00630 UPF0232 protein . 2 168 29.362 T 09-03-2017 IPR023007 Uncharacterised protein family UPF0232, actinobacteria UA74_RS00025 8231fcaa35ce24dff740b73887e9904a 181 Pfam PF05258 Protein of unknown function (DUF721) 70 156 7.8E-23 T 09-03-2017 IPR007922 Protein of unknown function DUF721/UPF0232 UA74_RS27580 43458408e142c5f3aa4550eea3115e24 329 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 72 291 1.2E-49 T 09-03-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 UA74_RS27580 43458408e142c5f3aa4550eea3115e24 329 Gene3D G3DSA:3.20.20.70 66 321 3.8E-86 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS27580 43458408e142c5f3aa4550eea3115e24 329 SMART SM01133 70 310 2.8E-62 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 UA74_RS27580 43458408e142c5f3aa4550eea3115e24 329 Pfam PF01791 DeoC/LacD family aldolase 67 305 7.7E-23 T 09-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 UA74_RS27580 43458408e142c5f3aa4550eea3115e24 329 SUPERFAMILY SSF51569 67 309 1.02E-69 T 09-03-2017 UA74_RS08645 c33117fc2f874435a1d3c24ef189fb74 221 Gene3D G3DSA:3.40.50.1000 68 215 2.0E-16 T 09-03-2017 IPR023214 HAD-like domain UA74_RS08645 c33117fc2f874435a1d3c24ef189fb74 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 187 2.1E-11 T 09-03-2017 IPR023214 HAD-like domain UA74_RS08645 c33117fc2f874435a1d3c24ef189fb74 221 SUPERFAMILY SSF56784 8 214 1.63E-30 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29415 c55fc84615d37cc2e01a0f13aab211b1 254 Pfam PF04672 S-adenosyl methyltransferase 1 234 2.2E-72 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS29415 c55fc84615d37cc2e01a0f13aab211b1 254 Gene3D G3DSA:3.40.50.150 1 253 7.1E-85 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS29415 c55fc84615d37cc2e01a0f13aab211b1 254 SUPERFAMILY SSF53335 1 221 6.53E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS29415 c55fc84615d37cc2e01a0f13aab211b1 254 PIRSF PIRSF017393 1 253 4.3E-78 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS23040 d9876c137d8058ae1eae176832f5ff74 897 SUPERFAMILY SSF55874 511 636 3.93E-21 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23040 d9876c137d8058ae1eae176832f5ff74 897 Pfam PF00672 HAMP domain 324 408 3.9E-10 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS23040 d9876c137d8058ae1eae176832f5ff74 897 SMART SM00387 524 637 2.4E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23040 d9876c137d8058ae1eae176832f5ff74 897 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 528 634 2.1E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23040 d9876c137d8058ae1eae176832f5ff74 897 Pfam PF08376 Nitrate and nitrite sensing 65 294 2.8E-21 T 09-03-2017 IPR013587 Nitrate/nitrite sensing protein UA74_RS23040 d9876c137d8058ae1eae176832f5ff74 897 Gene3D G3DSA:3.30.565.10 490 640 5.0E-20 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS20300 0deee83436bf4d9e55c7873e2f089ba7 282 SUPERFAMILY SSF47413 10 65 2.82E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS20300 0deee83436bf4d9e55c7873e2f089ba7 282 SMART SM00530 14 69 5.5E-10 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS20300 0deee83436bf4d9e55c7873e2f089ba7 282 Pfam PF13560 Helix-turn-helix domain 10 72 3.0E-12 T 09-03-2017 UA74_RS20300 0deee83436bf4d9e55c7873e2f089ba7 282 Gene3D G3DSA:1.10.260.40 6 65 6.1E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS00385 0dda86806b22ad4856f7714b51220185 266 Gene3D G3DSA:3.40.50.150 8 264 1.8E-93 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00385 0dda86806b22ad4856f7714b51220185 266 Pfam PF04672 S-adenosyl methyltransferase 10 265 1.2E-82 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS00385 0dda86806b22ad4856f7714b51220185 266 SUPERFAMILY SSF53335 10 244 1.79E-40 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00385 0dda86806b22ad4856f7714b51220185 266 PIRSF PIRSF017393 2 266 4.8E-85 T 09-03-2017 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_RS15855 b91d014d03f628b6cc6c4c7ebb791224 229 SUPERFAMILY SSF102588 6 225 4.05E-38 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS15855 b91d014d03f628b6cc6c4c7ebb791224 229 Gene3D G3DSA:3.40.50.10320 6 225 2.1E-43 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS15855 b91d014d03f628b6cc6c4c7ebb791224 229 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 131 1.2E-17 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_RS07135 3368a318b14fc17b18dc2efce39559ae 388 Pfam PF00953 Glycosyl transferase family 4 94 259 4.8E-30 T 09-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 UA74_RS14070 0fea4ec872f9a5b112bf48c1f0180940 129 Gene3D G3DSA:3.40.960.10 8 120 6.9E-42 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_RS14070 0fea4ec872f9a5b112bf48c1f0180940 129 Pfam PF03852 DNA mismatch endonuclease Vsr 1 60 2.6E-17 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_RS14070 0fea4ec872f9a5b112bf48c1f0180940 129 SUPERFAMILY SSF52980 1 118 2.47E-36 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS14070 0fea4ec872f9a5b112bf48c1f0180940 129 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 107 1.1E-36 T 09-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_RS17605 e5990b20c2ea281759ccda2713650b35 327 Gene3D G3DSA:3.40.50.720 3 179 3.0E-48 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17605 e5990b20c2ea281759ccda2713650b35 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 7.5E-58 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS17605 e5990b20c2ea281759ccda2713650b35 327 Gene3D G3DSA:3.90.25.10 180 318 8.1E-37 T 09-03-2017 UA74_RS17605 e5990b20c2ea281759ccda2713650b35 327 SUPERFAMILY SSF51735 3 317 1.1E-87 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17605 e5990b20c2ea281759ccda2713650b35 327 PRINTS PR01713 Nucleotide sugar epimerase signature 235 250 4.3E-5 T 09-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 UA74_RS17605 e5990b20c2ea281759ccda2713650b35 327 PRINTS PR01713 Nucleotide sugar epimerase signature 212 227 4.3E-5 T 09-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 UA74_RS17605 e5990b20c2ea281759ccda2713650b35 327 PRINTS PR01713 Nucleotide sugar epimerase signature 278 295 4.3E-5 T 09-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 UA74_RS21955 6878921e5c416952e51f562fd7884b21 135 SUPERFAMILY SSF50475 6 130 2.06E-28 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS21955 6878921e5c416952e51f562fd7884b21 135 Gene3D G3DSA:2.30.110.10 6 131 1.3E-29 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS21955 6878921e5c416952e51f562fd7884b21 135 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 12 127 3.3E-30 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS21955 6878921e5c416952e51f562fd7884b21 135 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 91 5.0E-14 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS03345 3a8c46de47f59f0b47ef21182d5f0fbc 145 Gene3D G3DSA:3.10.180.10 5 144 7.0E-10 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS03345 3a8c46de47f59f0b47ef21182d5f0fbc 145 SUPERFAMILY SSF54593 6 144 2.4E-10 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14660 f6b3cfb7831aeedbb1cd101611e2dd5f 172 Gene3D G3DSA:3.40.50.850 2 169 9.2E-33 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS14660 f6b3cfb7831aeedbb1cd101611e2dd5f 172 SUPERFAMILY SSF52499 2 137 6.02E-32 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS14660 f6b3cfb7831aeedbb1cd101611e2dd5f 172 Pfam PF00857 Isochorismatase family 4 141 1.5E-26 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS10450 576dce013626634a9d9bd6d66d904372 96 Gene3D G3DSA:3.40.50.1820 2 94 1.6E-13 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10450 576dce013626634a9d9bd6d66d904372 96 SUPERFAMILY SSF53474 4 93 5.74E-15 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS22285 d446b92472798ebff53850921d5aa911 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 4.2E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22285 d446b92472798ebff53850921d5aa911 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 4.2E-5 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22285 d446b92472798ebff53850921d5aa911 226 Gene3D G3DSA:1.10.357.10 5 196 2.8E-26 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS22285 d446b92472798ebff53850921d5aa911 226 SUPERFAMILY SSF46689 5 80 2.21E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22285 d446b92472798ebff53850921d5aa911 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 1.4E-11 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS23615 ce730e49e64f10e5ce74308d5563bf97 257 PIRSF PIRSF015736 11 252 1.3E-59 T 09-03-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_RS05250 2d6c20f1bece579e4650bc8e56f40cdb 70 Gene3D G3DSA:3.90.820.10 10 68 5.1E-29 T 09-03-2017 UA74_RS05250 2d6c20f1bece579e4650bc8e56f40cdb 70 SUPERFAMILY SSF160582 2 67 2.62E-26 T 09-03-2017 UA74_RS05250 2d6c20f1bece579e4650bc8e56f40cdb 70 SMART SM00923 2 52 1.8E-18 T 09-03-2017 IPR005153 MbtH-like protein UA74_RS05250 2d6c20f1bece579e4650bc8e56f40cdb 70 Pfam PF03621 MbtH-like protein 2 51 9.5E-20 T 09-03-2017 IPR005153 MbtH-like protein UA74_RS06940 5aca50478a19dddc51853fd8a8727a10 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 5.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS06940 5aca50478a19dddc51853fd8a8727a10 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 5.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS06940 5aca50478a19dddc51853fd8a8727a10 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 5.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS06940 5aca50478a19dddc51853fd8a8727a10 64 SUPERFAMILY SSF54862 2 62 1.26E-11 T 09-03-2017 UA74_RS06940 5aca50478a19dddc51853fd8a8727a10 64 Pfam PF13459 4Fe-4S single cluster domain 3 61 9.8E-12 T 09-03-2017 UA74_RS06940 5aca50478a19dddc51853fd8a8727a10 64 Gene3D G3DSA:3.30.70.20 1 64 2.4E-13 T 09-03-2017 UA74_RS23010 085310e5cbb4558542ce6884bb6330b9 299 Gene3D G3DSA:1.10.3720.10 28 287 3.3E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23010 085310e5cbb4558542ce6884bb6330b9 299 SUPERFAMILY SSF161098 31 299 3.79E-58 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23010 085310e5cbb4558542ce6884bb6330b9 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 293 6.2E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS25945 5a86f6551373c6d6a64698bec6143de2 190 Pfam PF12028 Protein of unknown function (DUF3515) 22 185 1.0E-47 T 09-03-2017 IPR021903 Protein of unknown function DUF3515 UA74_RS12620 846543aa0e46c7250c9b1fb70ae4dc86 111 Gene3D G3DSA:2.102.10.10 1 105 5.8E-28 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS12620 846543aa0e46c7250c9b1fb70ae4dc86 111 SUPERFAMILY SSF50022 1 105 4.84E-27 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS12620 846543aa0e46c7250c9b1fb70ae4dc86 111 Pfam PF00355 Rieske [2Fe-2S] domain 4 93 5.7E-17 T 09-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 90 98 7.8E-5 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 256 274 7.8E-5 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 134 158 7.8E-5 T 09-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 Gene3D G3DSA:3.50.50.60 1 100 3.9E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 Gene3D G3DSA:3.50.50.60 149 298 8.1E-26 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 274 2.7E-41 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 SUPERFAMILY SSF51905 1 155 1.1E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 SUPERFAMILY SSF51905 185 310 1.1E-32 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.7E-8 T 09-03-2017 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 268 3.7E-8 T 09-03-2017 UA74_RS10000 eefb43ece04cbcdcfc9e5ae8a39e5f7d 383 Gene3D G3DSA:3.50.50.60 101 148 7.6E-4 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS21800 a5d548f3956a924c7207d5b1827e539b 150 Gene3D G3DSA:3.30.420.10 8 149 3.9E-57 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS21800 a5d548f3956a924c7207d5b1827e539b 150 SUPERFAMILY SSF53098 8 148 1.14E-53 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS21800 a5d548f3956a924c7207d5b1827e539b 150 Pfam PF00075 RNase H 9 147 6.2E-50 T 09-03-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 UA74_RS21800 a5d548f3956a924c7207d5b1827e539b 150 Hamap MF_00042 Ribonuclease H [rnhA]. 7 150 31.541 T 09-03-2017 IPR022892 Ribonuclease H GO:0004523 UA74_RS16140 dc3fa64043bea427e6ced2c6a9a772c7 60 Pfam PF13560 Helix-turn-helix domain 2 46 6.2E-7 T 09-03-2017 UA74_RS16140 dc3fa64043bea427e6ced2c6a9a772c7 60 SUPERFAMILY SSF47413 1 50 1.56E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16140 dc3fa64043bea427e6ced2c6a9a772c7 60 Gene3D G3DSA:1.10.260.40 1 50 4.0E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25570 6f2b7cae7c053f55e3b808559624d67d 272 Pfam PF05552 Conserved TM helix 103 145 1.2E-7 T 09-03-2017 IPR008910 Conserved TM helix UA74_RS25570 6f2b7cae7c053f55e3b808559624d67d 272 Pfam PF05552 Conserved TM helix 11 55 1.8E-12 T 09-03-2017 IPR008910 Conserved TM helix UA74_RS30435 f7ff8cfb6ee6fc1b5b7e638973169174 299 Pfam PF13614 AAA domain 39 216 3.1E-57 T 09-03-2017 IPR025669 AAA domain UA74_RS30435 f7ff8cfb6ee6fc1b5b7e638973169174 299 SUPERFAMILY SSF52540 39 289 7.75E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS30435 f7ff8cfb6ee6fc1b5b7e638973169174 299 Gene3D G3DSA:3.40.50.300 39 290 7.7E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19160 2ed61db0427b3d9df1645135ad931904 113 Gene3D G3DSA:1.10.10.10 4 107 1.3E-30 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19160 2ed61db0427b3d9df1645135ad931904 113 SUPERFAMILY SSF46785 5 106 5.93E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19160 2ed61db0427b3d9df1645135ad931904 113 Pfam PF03551 Transcriptional regulator PadR-like family 17 89 1.2E-20 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS30460 76992c5de1b4d18f6ccdabbb4e7a61c3 102 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 21 91 1.3E-27 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor UA74_RS30460 76992c5de1b4d18f6ccdabbb4e7a61c3 102 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 30 82 2.0E-19 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor UA74_RS30460 76992c5de1b4d18f6ccdabbb4e7a61c3 102 Pfam PF01809 Haemolytic domain 17 82 3.5E-28 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor UA74_RS30460 76992c5de1b4d18f6ccdabbb4e7a61c3 102 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 15 83 24.494 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor UA74_RS30460 76992c5de1b4d18f6ccdabbb4e7a61c3 102 SMART SM01234 15 82 3.8E-43 T 09-03-2017 IPR002696 Putative membrane protein insertion efficiency factor UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 SUPERFAMILY SSF48264 17 402 5.89E-106 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 293 320 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 275 286 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 159 174 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 351 362 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 142 158 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 96 107 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 194 216 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 342 351 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 321 336 7.7E-62 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 Pfam PF00067 Cytochrome P450 175 267 2.7E-8 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 Pfam PF00067 Cytochrome P450 273 372 5.3E-16 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS09875 cc148c5bda26bf2f9d7eed987b5dff90 404 Gene3D G3DSA:1.10.630.10 9 402 3.4E-141 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS11070 ff65dc5a6ff42a7f80b42c5f8ed13739 142 Gene3D G3DSA:2.60.120.10 20 116 1.8E-22 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS11070 ff65dc5a6ff42a7f80b42c5f8ed13739 142 Pfam PF07883 Cupin domain 45 107 4.9E-17 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS11070 ff65dc5a6ff42a7f80b42c5f8ed13739 142 SUPERFAMILY SSF51182 20 134 2.97E-27 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS11070 ff65dc5a6ff42a7f80b42c5f8ed13739 142 PIRSF PIRSF016602 1 139 9.5E-53 T 09-03-2017 IPR016672 Polyketide biosynthesis protein CurC, predicted UA74_RS07565 128a30442aea0a5dcf0a5904d7167de0 385 Pfam PF07730 Histidine kinase 185 249 1.1E-16 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS07565 128a30442aea0a5dcf0a5904d7167de0 385 SUPERFAMILY SSF55874 266 380 4.85E-14 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS07565 128a30442aea0a5dcf0a5904d7167de0 385 Gene3D G3DSA:3.30.565.10 296 381 8.5E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS22735 63ec771509f0150635e11b6628c6623f 320 SUPERFAMILY SSF161098 94 280 9.27E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22735 63ec771509f0150635e11b6628c6623f 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 290 4.5E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22735 63ec771509f0150635e11b6628c6623f 320 Gene3D G3DSA:1.10.3720.10 92 293 2.1E-19 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS23735 b2cd33c072a49fec73b66eb1d76d2662 145 Pfam PF03780 Asp23 family, cell envelope-related function 20 130 8.5E-33 T 09-03-2017 IPR005531 Alkaline shock protein Asp23 UA74_RS02885 ea9466da2773d9c4afb5edbf3bd7ba58 392 SUPERFAMILY SSF55874 265 376 5.47E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS02885 ea9466da2773d9c4afb5edbf3bd7ba58 392 Pfam PF07730 Histidine kinase 197 262 3.1E-13 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS20175 2ebbbc5f58d96c28bec3f36bcfad3a45 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.0E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS20175 2ebbbc5f58d96c28bec3f36bcfad3a45 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.0E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS20175 2ebbbc5f58d96c28bec3f36bcfad3a45 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.0E-6 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS20175 2ebbbc5f58d96c28bec3f36bcfad3a45 157 SMART SM00347 28 133 7.6E-15 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS20175 2ebbbc5f58d96c28bec3f36bcfad3a45 157 Pfam PF01047 MarR family 44 96 9.2E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS20175 2ebbbc5f58d96c28bec3f36bcfad3a45 157 SUPERFAMILY SSF46785 18 149 3.28E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20175 2ebbbc5f58d96c28bec3f36bcfad3a45 157 Gene3D G3DSA:1.10.10.10 19 146 8.1E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18495 ce9d332d04eeea89f8d9160b3893d342 386 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 83 210 1.4E-30 T 09-03-2017 UA74_RS18495 ce9d332d04eeea89f8d9160b3893d342 386 SUPERFAMILY SSF53335 85 213 1.78E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS18495 ce9d332d04eeea89f8d9160b3893d342 386 Gene3D G3DSA:3.40.50.150 17 241 1.6E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04115 2cbd84067fbbe56a8fb87d1ca0a126a7 312 SUPERFAMILY SSF103481 31 54 7.85E-12 T 09-03-2017 UA74_RS04115 2cbd84067fbbe56a8fb87d1ca0a126a7 312 SUPERFAMILY SSF103481 84 159 7.85E-12 T 09-03-2017 UA74_RS04115 2cbd84067fbbe56a8fb87d1ca0a126a7 312 Pfam PF00892 EamA-like transporter family 164 297 3.7E-10 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS04115 2cbd84067fbbe56a8fb87d1ca0a126a7 312 Pfam PF00892 EamA-like transporter family 73 155 5.0E-9 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS04115 2cbd84067fbbe56a8fb87d1ca0a126a7 312 SUPERFAMILY SSF103481 210 298 7.32E-7 T 09-03-2017 UA74_RS04430 c0eeb725065d2b5401e4a94f4b759779 332 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 17 279 4.0E-87 T 09-03-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS04430 c0eeb725065d2b5401e4a94f4b759779 332 Gene3D G3DSA:3.40.50.10320 14 286 8.7E-77 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS04430 c0eeb725065d2b5401e4a94f4b759779 332 SUPERFAMILY SSF102588 15 281 2.09E-57 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS04430 c0eeb725065d2b5401e4a94f4b759779 332 Pfam PF02585 GlcNAc-PI de-N-acetylase 17 174 1.3E-24 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_RS04430 c0eeb725065d2b5401e4a94f4b759779 332 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 16 301 35.548 T 09-03-2017 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 535 3.8E-75 T 09-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 SUPERFAMILY SSF103473 267 439 4.32E-66 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 SUPERFAMILY SSF103473 512 536 4.32E-66 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 SUPERFAMILY SSF103473 21 214 4.32E-66 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 Pfam PF07690 Major Facilitator Superfamily 31 429 1.1E-50 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 Gene3D G3DSA:1.20.1250.20 513 538 2.0E-23 T 09-03-2017 UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 Gene3D G3DSA:1.20.1250.20 31 212 7.8E-33 T 09-03-2017 UA74_RS01465 b47e3db4e92631ed02a5d8f48f618204 600 Gene3D G3DSA:1.20.1250.20 285 441 2.0E-23 T 09-03-2017 UA74_RS18825 ad16b06ee71c6a65f7025daa5b7274f6 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 289 2.4E-18 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18825 ad16b06ee71c6a65f7025daa5b7274f6 296 Gene3D G3DSA:1.10.3720.10 67 294 1.5E-65 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18825 ad16b06ee71c6a65f7025daa5b7274f6 296 SUPERFAMILY SSF161098 63 287 3.92E-61 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS09155 6274f79cd0b55aa5d4466c45c34aee42 406 Gene3D G3DSA:1.20.1250.20 217 398 3.6E-12 T 09-03-2017 UA74_RS09155 6274f79cd0b55aa5d4466c45c34aee42 406 Pfam PF07690 Major Facilitator Superfamily 31 366 1.0E-16 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS09155 6274f79cd0b55aa5d4466c45c34aee42 406 Gene3D G3DSA:1.20.1250.20 29 210 2.3E-15 T 09-03-2017 UA74_RS09155 6274f79cd0b55aa5d4466c45c34aee42 406 SUPERFAMILY SSF103473 26 402 4.32E-39 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS12735 2e9a344ab383b28f83e57e10cf17737a 242 Pfam PF13580 SIS domain 15 144 5.1E-36 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS12735 2e9a344ab383b28f83e57e10cf17737a 242 SUPERFAMILY SSF53697 18 203 4.89E-18 T 09-03-2017 UA74_RS12735 2e9a344ab383b28f83e57e10cf17737a 242 Gene3D G3DSA:3.40.50.10490 14 233 3.6E-50 T 09-03-2017 UA74_RS03140 8427a0eb9697a5320060f7883b549df4 180 Pfam PF01196 Ribosomal protein L17 20 116 3.4E-34 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03140 8427a0eb9697a5320060f7883b549df4 180 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 116 1.6E-38 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03140 8427a0eb9697a5320060f7883b549df4 180 SUPERFAMILY SSF64263 1 118 2.49E-45 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03140 8427a0eb9697a5320060f7883b549df4 180 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.527 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS03140 8427a0eb9697a5320060f7883b549df4 180 Gene3D G3DSA:3.90.1030.10 3 117 8.8E-44 T 09-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS11695 c8e5a9db8f5caf2ed5e12286d0514a11 164 SUPERFAMILY SSF50891 5 147 9.86E-9 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS11695 c8e5a9db8f5caf2ed5e12286d0514a11 164 Pfam PF12903 Protein of unknown function (DUF3830) 7 161 1.1E-60 T 09-03-2017 IPR024532 Protein of unknown function DUF3830 UA74_RS23815 40aa77d0c0a8739ea5e270a8956d8b77 184 Pfam PF11452 Protein of unknown function (DUF3000) 8 178 2.5E-69 T 09-03-2017 IPR021555 Protein of unknown function DUF3000 UA74_RS28785 c9ad8d19f5f0d8189298dec1a675366a 259 SUPERFAMILY SSF88946 5 109 2.98E-19 T 09-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28785 c9ad8d19f5f0d8189298dec1a675366a 259 Pfam PF04542 Sigma-70 region 2 28 95 3.1E-11 T 09-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28785 c9ad8d19f5f0d8189298dec1a675366a 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 182 1.1E-23 T 09-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28785 c9ad8d19f5f0d8189298dec1a675366a 259 SUPERFAMILY SSF88659 114 185 4.49E-9 T 09-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_RS28785 c9ad8d19f5f0d8189298dec1a675366a 259 Gene3D G3DSA:1.10.1740.10 7 115 1.3E-19 T 09-03-2017 UA74_RS28785 c9ad8d19f5f0d8189298dec1a675366a 259 Gene3D G3DSA:1.10.10.10 125 186 1.9E-6 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20875 2eaccbe0158b154b0b34dbab823b77aa 435 Pfam PF02687 FtsX-like permease family 311 428 4.1E-12 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS08130 57391b1bb3a461c794e78f43c284080d 265 SUPERFAMILY SSF55846 3 161 7.77E-27 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS08130 57391b1bb3a461c794e78f43c284080d 265 SUPERFAMILY SSF47090 187 245 9.02E-11 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS08130 57391b1bb3a461c794e78f43c284080d 265 SMART SM00701 2 126 6.2E-4 T 09-03-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 UA74_RS08130 57391b1bb3a461c794e78f43c284080d 265 Gene3D G3DSA:1.10.101.10 190 244 1.2E-13 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS08130 57391b1bb3a461c794e78f43c284080d 265 Gene3D G3DSA:3.40.80.10 3 161 3.5E-28 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS08130 57391b1bb3a461c794e78f43c284080d 265 Pfam PF01471 Putative peptidoglycan binding domain 192 244 2.8E-9 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS26405 67cb587f3c9c76cf5b695ca5959ef14d 125 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 24 50 7.0E-9 T 09-03-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 UA74_RS26405 67cb587f3c9c76cf5b695ca5959ef14d 125 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 50 77 7.0E-9 T 09-03-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 UA74_RS26405 67cb587f3c9c76cf5b695ca5959ef14d 125 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 100 116 7.0E-9 T 09-03-2017 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 UA74_RS26405 67cb587f3c9c76cf5b695ca5959ef14d 125 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 25 115 1.0E-11 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 UA74_RS26405 67cb587f3c9c76cf5b695ca5959ef14d 125 Pfam PF00720 Subtilisin inhibitor-like 22 111 2.2E-21 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 UA74_RS26405 67cb587f3c9c76cf5b695ca5959ef14d 125 Gene3D G3DSA:3.30.350.10 36 125 1.1E-28 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 UA74_RS26405 67cb587f3c9c76cf5b695ca5959ef14d 125 SUPERFAMILY SSF55399 22 125 3.4E-25 T 09-03-2017 IPR023549 Subtilisin inhibitor GO:0004867 UA74_RS18100 6490a9209550d33a59dfdfc23e7333a0 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 65 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS18100 6490a9209550d33a59dfdfc23e7333a0 208 Gene3D G3DSA:1.10.357.10 8 201 2.4E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS18100 6490a9209550d33a59dfdfc23e7333a0 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.2E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS18100 6490a9209550d33a59dfdfc23e7333a0 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.2E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS18100 6490a9209550d33a59dfdfc23e7333a0 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 4.3E-17 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS18100 6490a9209550d33a59dfdfc23e7333a0 208 SUPERFAMILY SSF46689 10 87 4.0E-21 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS17280 02b3a0c816ff6cfd9113952830273de2 346 SUPERFAMILY SSF48264 36 253 1.09E-29 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17280 02b3a0c816ff6cfd9113952830273de2 346 Gene3D G3DSA:1.10.630.10 36 253 2.6E-34 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS17280 02b3a0c816ff6cfd9113952830273de2 346 PRINTS PR00359 B-class P450 signature 212 223 6.9E-5 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17280 02b3a0c816ff6cfd9113952830273de2 346 PRINTS PR00359 B-class P450 signature 76 92 6.9E-5 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS17280 02b3a0c816ff6cfd9113952830273de2 346 PRINTS PR00359 B-class P450 signature 230 257 6.9E-5 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS24865 21ae009c8fa442ea214d7816c023da05 274 Gene3D G3DSA:1.10.260.40 11 63 1.5E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24865 21ae009c8fa442ea214d7816c023da05 274 Pfam PF13560 Helix-turn-helix domain 5 66 6.2E-10 T 09-03-2017 UA74_RS24865 21ae009c8fa442ea214d7816c023da05 274 SMART SM00530 8 64 1.6E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS24865 21ae009c8fa442ea214d7816c023da05 274 SUPERFAMILY SSF47413 11 63 9.65E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16620 9cefc596936a5aaa488cc0a5ee24f1bd 502 SUPERFAMILY SSF103473 6 195 2.62E-64 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16620 9cefc596936a5aaa488cc0a5ee24f1bd 502 SUPERFAMILY SSF103473 246 460 2.62E-64 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16620 9cefc596936a5aaa488cc0a5ee24f1bd 502 Pfam PF07690 Major Facilitator Superfamily 15 408 2.3E-44 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS16620 9cefc596936a5aaa488cc0a5ee24f1bd 502 Gene3D G3DSA:1.20.1250.20 263 462 3.3E-16 T 09-03-2017 UA74_RS16620 9cefc596936a5aaa488cc0a5ee24f1bd 502 Gene3D G3DSA:1.20.1250.20 8 195 2.4E-30 T 09-03-2017 UA74_RS10380 3a0a036a43201c2706f1a17549a2d67c 547 SUPERFAMILY SSF75304 50 538 1.31E-122 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS10380 3a0a036a43201c2706f1a17549a2d67c 547 Gene3D G3DSA:3.90.1300.10 50 542 2.9E-142 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS10380 3a0a036a43201c2706f1a17549a2d67c 547 Pfam PF01425 Amidase 72 522 2.5E-101 T 09-03-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_RS20740 51cc2af39db8fd352bce3816ec6ad632 223 Gene3D G3DSA:1.10.10.10 127 221 5.7E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20740 51cc2af39db8fd352bce3816ec6ad632 223 SMART SM00448 2 112 7.6E-42 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS20740 51cc2af39db8fd352bce3816ec6ad632 223 Pfam PF00072 Response regulator receiver domain 5 112 4.1E-28 T 09-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_RS20740 51cc2af39db8fd352bce3816ec6ad632 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 220 4.6E-26 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS20740 51cc2af39db8fd352bce3816ec6ad632 223 Gene3D G3DSA:3.40.50.2300 3 121 2.5E-39 T 09-03-2017 UA74_RS20740 51cc2af39db8fd352bce3816ec6ad632 223 SUPERFAMILY SSF52172 3 179 5.57E-41 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS20740 51cc2af39db8fd352bce3816ec6ad632 223 SMART SM00862 144 220 4.2E-27 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS22885 ffba9ad344f79873b984f01383ecf7f8 141 Pfam PF07702 UTRA domain 4 131 6.7E-30 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS22885 ffba9ad344f79873b984f01383ecf7f8 141 SMART SM00866 2 132 2.4E-20 T 09-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_RS22885 ffba9ad344f79873b984f01383ecf7f8 141 SUPERFAMILY SSF64288 4 137 1.35E-33 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS22885 ffba9ad344f79873b984f01383ecf7f8 141 Gene3D G3DSA:3.40.1410.10 3 135 1.8E-48 T 09-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain UA74_RS17690 15912ac93d89b141fd9488886919fb71 175 ProSitePatterns PS00018 EF-hand calcium-binding domain. 67 79 - T 09-03-2017 IPR018247 EF-Hand 1, calcium-binding site UA74_RS17690 15912ac93d89b141fd9488886919fb71 175 SUPERFAMILY SSF47473 4 165 3.73E-19 T 09-03-2017 IPR011992 EF-hand domain pair UA74_RS17690 15912ac93d89b141fd9488886919fb71 175 SMART SM00054 58 86 8.2 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 UA74_RS17690 15912ac93d89b141fd9488886919fb71 175 SMART SM00054 8 36 12.0 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 UA74_RS17690 15912ac93d89b141fd9488886919fb71 175 SMART SM00054 96 124 28.0 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 UA74_RS17690 15912ac93d89b141fd9488886919fb71 175 Pfam PF13833 EF-hand domain pair 61 83 0.0017 T 09-03-2017 IPR002048 EF-hand domain GO:0005509 UA74_RS17690 15912ac93d89b141fd9488886919fb71 175 Gene3D G3DSA:1.10.238.10 6 160 2.5E-16 T 09-03-2017 IPR011992 EF-hand domain pair UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 565 595 - T 09-03-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 504 522 1.7E-41 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 554 1.7E-41 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 662 684 1.7E-41 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 588 608 1.7E-41 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 643 658 1.7E-41 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 558 577 1.7E-41 T 09-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 Gene3D G3DSA:3.40.50.1820 407 730 1.7E-80 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 5 204 1.3E-13 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 278 453 5.4E-18 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 Pfam PF00326 Prolyl oligopeptidase family 527 731 6.5E-50 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 Gene3D G3DSA:2.130.10.120 95 193 7.4E-14 T 09-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 SUPERFAMILY SSF50993 3 206 2.46E-39 T 09-03-2017 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 SUPERFAMILY SSF50993 275 453 2.46E-39 T 09-03-2017 UA74_RS12880 da7d34d3a1a461933bcd1ad25d697839 793 SUPERFAMILY SSF53474 471 729 1.5E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01340 796b77bf0971b552596664ccd02a366c 436 PIRSF PIRSF016719 20 436 1.3E-135 T 09-03-2017 IPR008302 Uncharacterised conserved protein UCP016719 UA74_RS01340 796b77bf0971b552596664ccd02a366c 436 Pfam PF07075 Protein of unknown function (DUF1343) 72 435 6.5E-130 T 09-03-2017 IPR008302 Uncharacterised conserved protein UCP016719 UA74_RS07955 0f2a785b4586a05fdaa0c40023401048 141 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 129 4.2E-17 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UA74_RS07955 0f2a785b4586a05fdaa0c40023401048 141 PIRSF PIRSF002070 1 138 1.2E-16 T 09-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UA74_RS07955 0f2a785b4586a05fdaa0c40023401048 141 SUPERFAMILY SSF50249 4 129 2.95E-28 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS07955 0f2a785b4586a05fdaa0c40023401048 141 Gene3D G3DSA:2.40.50.140 2 114 1.9E-28 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS07955 0f2a785b4586a05fdaa0c40023401048 141 Pfam PF00436 Single-strand binding protein family 5 104 1.3E-16 T 09-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 UA74_RS03725 599f55d260ba842b406903267ce3ad68 294 SUPERFAMILY SSF53955 119 286 1.69E-35 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS03725 599f55d260ba842b406903267ce3ad68 294 Gene3D G3DSA:1.10.530.10 139 166 8.8E-10 T 09-03-2017 UA74_RS03725 599f55d260ba842b406903267ce3ad68 294 Gene3D G3DSA:1.10.530.10 206 283 8.8E-10 T 09-03-2017 UA74_RS03725 599f55d260ba842b406903267ce3ad68 294 Pfam PF13406 Transglycosylase SLT domain 204 263 1.6E-8 T 09-03-2017 IPR031304 Transglycosylase SLT domain 2 UA74_RS14305 2010f51c1f412e49b77f5fb6453371ce 682 Gene3D G3DSA:1.50.10.10 313 550 1.1E-14 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS14305 2010f51c1f412e49b77f5fb6453371ce 682 SUPERFAMILY SSF48208 277 677 6.97E-50 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS21940 af276f96df52394aff2678024b63ec38 287 Gene3D G3DSA:3.40.50.720 3 244 6.0E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21940 af276f96df52394aff2678024b63ec38 287 SUPERFAMILY SSF51735 3 245 1.1E-40 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21940 af276f96df52394aff2678024b63ec38 287 Pfam PF00106 short chain dehydrogenase 7 210 2.9E-22 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21940 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.6E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21940 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 5.6E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21940 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 5.6E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21940 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.6E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21940 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 5.6E-15 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS24790 90be9bea9425165ef691c69bdc26d82c 294 Gene3D G3DSA:3.20.20.220 3 291 8.3E-100 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like UA74_RS24790 90be9bea9425165ef691c69bdc26d82c 294 SUPERFAMILY SSF51730 3 290 1.04E-90 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like UA74_RS24790 90be9bea9425165ef691c69bdc26d82c 294 Pfam PF02219 Methylenetetrahydrofolate reductase 7 288 1.5E-90 T 09-03-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 UA74_RS24790 90be9bea9425165ef691c69bdc26d82c 294 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 15 287 6.3E-90 T 09-03-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 UA74_RS12830 a1fdb5dbd6575c61ef049468f931c591 259 Pfam PF08241 Methyltransferase domain 55 145 5.8E-21 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS12830 a1fdb5dbd6575c61ef049468f931c591 259 Gene3D G3DSA:3.40.50.150 31 148 1.2E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12830 a1fdb5dbd6575c61ef049468f931c591 259 SUPERFAMILY SSF53335 14 197 5.41E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04085 f0e23523942314dea6bfffc1fc992a64 217 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 8 214 2.8E-59 T 09-03-2017 IPR005744 Hly-III GO:0016021|GO:0019835 UA74_RS04085 f0e23523942314dea6bfffc1fc992a64 217 Pfam PF03006 Haemolysin-III related 7 208 3.4E-44 T 09-03-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 UA74_RS27645 e3de1ae66d3a95d7eb3cf718265962f2 386 SUPERFAMILY SSF58113 73 219 1.57E-5 T 09-03-2017 UA74_RS27645 e3de1ae66d3a95d7eb3cf718265962f2 386 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 2 294 1.0E-5 T 09-03-2017 UA74_RS27645 e3de1ae66d3a95d7eb3cf718265962f2 386 SUPERFAMILY SSF58113 188 301 1.22E-6 T 09-03-2017 UA74_RS24595 a3bb782a297795af2096f4991ba54660 195 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 176 21.0 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UA74_RS24595 a3bb782a297795af2096f4991ba54660 195 SUPERFAMILY SSF55486 7 150 1.07E-37 T 09-03-2017 UA74_RS24595 a3bb782a297795af2096f4991ba54660 195 Pfam PF02130 Uncharacterized protein family UPF0054 19 147 5.6E-36 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UA74_RS24595 a3bb782a297795af2096f4991ba54660 195 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 09-03-2017 IPR020549 Endoribonuclease YbeY, conserved site UA74_RS24595 a3bb782a297795af2096f4991ba54660 195 Gene3D G3DSA:3.40.390.30 7 154 2.2E-42 T 09-03-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 UA74_RS24595 a3bb782a297795af2096f4991ba54660 195 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 2.9E-31 T 09-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 SUPERFAMILY SSF46565 1 65 2.75E-22 T 09-03-2017 IPR001623 DnaJ domain UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 PRINTS PR00625 DnaJ domain signature 23 38 3.7E-7 T 09-03-2017 IPR001623 DnaJ domain UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 PRINTS PR00625 DnaJ domain signature 5 23 3.7E-7 T 09-03-2017 IPR001623 DnaJ domain UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 SMART SM00271 2 56 8.7E-18 T 09-03-2017 IPR001623 DnaJ domain UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 Gene3D G3DSA:1.10.287.110 2 62 5.6E-20 T 09-03-2017 IPR001623 DnaJ domain UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 41 60 - T 09-03-2017 IPR018253 DnaJ domain, conserved site UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 Pfam PF08378 Nuclease-related domain 219 288 9.2E-5 T 09-03-2017 IPR011528 Nuclease-related domain, NERD UA74_RS06155 9e9a4904b071cecccbe4af472a4537b5 376 Pfam PF00226 DnaJ domain 3 61 1.2E-16 T 09-03-2017 IPR001623 DnaJ domain UA74_RS00570 7f40f6c3e5f11d05bb29cee6d99f3833 197 Gene3D G3DSA:3.40.220.10 12 193 6.4E-46 T 09-03-2017 UA74_RS00570 7f40f6c3e5f11d05bb29cee6d99f3833 197 SUPERFAMILY SSF52949 17 192 9.42E-26 T 09-03-2017 UA74_RS00570 7f40f6c3e5f11d05bb29cee6d99f3833 197 SMART SM00506 40 185 6.1E-12 T 09-03-2017 IPR002589 Macro domain UA74_RS00570 7f40f6c3e5f11d05bb29cee6d99f3833 197 Pfam PF01661 Macro domain 57 183 4.6E-12 T 09-03-2017 IPR002589 Macro domain UA74_RS24960 93c724f49687c8c8fc130ac9bd10e2a9 256 PIRSF PIRSF017388 3 248 7.3E-61 T 09-03-2017 IPR012354 Esterase/lipase GO:0052689 UA74_RS24960 93c724f49687c8c8fc130ac9bd10e2a9 256 Gene3D G3DSA:3.40.50.1820 16 246 4.0E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24960 93c724f49687c8c8fc130ac9bd10e2a9 256 Pfam PF12146 Serine aminopeptidase, S33 20 220 3.2E-18 T 09-03-2017 IPR022742 Serine aminopeptidase, S33 UA74_RS24960 93c724f49687c8c8fc130ac9bd10e2a9 256 SUPERFAMILY SSF53474 19 246 7.84E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS28335 ec4c1330760a61dfd170955d971fbb26 592 Pfam PF00246 Zinc carboxypeptidase 141 442 1.8E-46 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS28335 ec4c1330760a61dfd170955d971fbb26 592 Gene3D G3DSA:3.40.630.10 129 475 3.9E-68 T 09-03-2017 UA74_RS28335 ec4c1330760a61dfd170955d971fbb26 592 SUPERFAMILY SSF53187 128 474 3.97E-62 T 09-03-2017 UA74_RS28335 ec4c1330760a61dfd170955d971fbb26 592 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 197 211 5.3E-5 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS28335 ec4c1330760a61dfd170955d971fbb26 592 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 366 379 5.3E-5 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS28335 ec4c1330760a61dfd170955d971fbb26 592 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 298 306 5.3E-5 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS28335 ec4c1330760a61dfd170955d971fbb26 592 SMART SM00631 133 465 3.9E-42 T 09-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_RS23175 8c173f514016536694799160b6f2fb8c 542 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 4 488 4.2E-96 T 09-03-2017 IPR013381 CRISPR-associated protein Cse1 UA74_RS23175 8c173f514016536694799160b6f2fb8c 542 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 4 339 2.4E-47 T 09-03-2017 IPR013381 CRISPR-associated protein Cse1 UA74_RS22975 e36120bd9f5e549a1ac465f5791b873a 198 SUPERFAMILY SSF48498 78 186 8.9E-7 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS22975 e36120bd9f5e549a1ac465f5791b873a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.9E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22975 e36120bd9f5e549a1ac465f5791b873a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.9E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22975 e36120bd9f5e549a1ac465f5791b873a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 2.3E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS22975 e36120bd9f5e549a1ac465f5791b873a 198 SUPERFAMILY SSF46689 4 72 1.9E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS22975 e36120bd9f5e549a1ac465f5791b873a 198 Gene3D G3DSA:1.10.357.10 3 185 9.0E-28 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06695 47f6bae79389cb252ec6aea2c76791a5 182 Pfam PF02441 Flavoprotein 73 129 1.1E-10 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_RS06695 47f6bae79389cb252ec6aea2c76791a5 182 Gene3D G3DSA:3.40.50.1950 20 179 1.8E-17 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_RS06695 47f6bae79389cb252ec6aea2c76791a5 182 SUPERFAMILY SSF52507 11 178 4.06E-20 T 09-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_RS08820 97b4208af97d28813d7fd011285d0aab 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 246 6.7E-58 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS08820 97b4208af97d28813d7fd011285d0aab 320 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 315 4.5E-118 T 09-03-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 UA74_RS08820 97b4208af97d28813d7fd011285d0aab 320 Gene3D G3DSA:3.40.50.720 3 168 2.0E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08820 97b4208af97d28813d7fd011285d0aab 320 SUPERFAMILY SSF51735 2 314 2.05E-88 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08820 97b4208af97d28813d7fd011285d0aab 320 Gene3D G3DSA:3.90.25.10 169 315 1.5E-44 T 09-03-2017 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 182 487 4.9E-109 T 09-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 342 349 - T 09-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 30 145 6.6E-20 T 09-03-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 279 300 5.6E-48 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 338 358 5.6E-48 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 316 337 5.6E-48 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 366 381 5.6E-48 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 257 274 5.6E-48 T 09-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 6 496 33.73 T 09-03-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 SUPERFAMILY SSF53187 176 494 1.91E-106 T 09-03-2017 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 SUPERFAMILY SSF52949 19 154 4.24E-21 T 09-03-2017 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 Gene3D G3DSA:3.40.630.10 175 496 2.9E-125 T 09-03-2017 UA74_RS25200 35e59dc81b7cd9929f0e2d07d205fef8 498 Gene3D G3DSA:3.40.220.10 18 174 5.4E-28 T 09-03-2017 UA74_RS14570 c75f8f55d0d2d1400e2caeebd3728f2e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.2E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS14570 c75f8f55d0d2d1400e2caeebd3728f2e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 9.2E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS14570 c75f8f55d0d2d1400e2caeebd3728f2e 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 09-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_RS14570 c75f8f55d0d2d1400e2caeebd3728f2e 213 SUPERFAMILY SSF46689 16 88 2.29E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14570 c75f8f55d0d2d1400e2caeebd3728f2e 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.0E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS14570 c75f8f55d0d2d1400e2caeebd3728f2e 213 Gene3D G3DSA:1.10.357.10 6 211 9.9E-40 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS11190 b43b10c1e0069242c69ad0919e8216db 629 Pfam PF07907 YibE/F-like protein 204 442 4.5E-71 T 09-03-2017 IPR012507 YibE/F-like UA74_RS17320 19c419d2e5cd7fd6c0cd985895ac06ef 349 Gene3D G3DSA:3.40.50.150 107 277 3.4E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17320 19c419d2e5cd7fd6c0cd985895ac06ef 349 SUPERFAMILY SSF53335 82 289 4.5E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17320 19c419d2e5cd7fd6c0cd985895ac06ef 349 Pfam PF13489 Methyltransferase domain 97 264 1.1E-19 T 09-03-2017 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 SUPERFAMILY SSF51556 61 388 2.38E-87 T 09-03-2017 IPR032466 Metal-dependent hydrolase UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 23 446 1.3E-127 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 Pfam PF01979 Amidohydrolase family 58 441 8.6E-19 T 09-03-2017 IPR006680 Amidohydrolase-related GO:0016787 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 SUPERFAMILY SSF51338 21 60 9.99E-23 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 SUPERFAMILY SSF51338 389 450 9.99E-23 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 ProSitePatterns PS00483 Dihydroorotase signature 2. 323 334 - T 09-03-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 Gene3D G3DSA:3.20.20.140 75 429 1.2E-97 T 09-03-2017 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 Hamap MF_00220_B Dihydroorotase [pyrC]. 10 447 40.297 T 09-03-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 UA74_RS12285 9752654f2d7b72156c3bfa1626426e5c 456 Gene3D G3DSA:2.30.40.10 23 74 3.3E-15 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 Gene3D G3DSA:3.50.50.60 4 183 5.5E-19 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 Gene3D G3DSA:3.50.50.60 301 334 5.5E-19 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.5E-5 T 09-03-2017 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 1.5E-5 T 09-03-2017 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 318 1.5E-5 T 09-03-2017 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 Pfam PF01494 FAD binding domain 109 335 3.9E-5 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 SUPERFAMILY SSF51905 3 186 1.15E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS11220 56e275fe5e51760f76ea8247979ff129 439 SUPERFAMILY SSF51905 298 370 1.15E-27 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16625 5dbd8d031bca812d3f515c364813c42d 229 SUPERFAMILY SSF46689 11 74 1.44E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS16625 5dbd8d031bca812d3f515c364813c42d 229 SUPERFAMILY SSF48498 83 220 1.45E-12 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS16625 5dbd8d031bca812d3f515c364813c42d 229 Gene3D G3DSA:1.10.357.10 9 223 4.1E-38 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS16625 5dbd8d031bca812d3f515c364813c42d 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 3.8E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS23465 72ab051608fa4d0ea05c63be256a7d38 159 SUPERFAMILY SSF55961 7 149 7.47E-40 T 09-03-2017 UA74_RS23465 72ab051608fa4d0ea05c63be256a7d38 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 148 3.7E-28 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS23465 72ab051608fa4d0ea05c63be256a7d38 159 Gene3D G3DSA:3.30.530.20 8 152 5.7E-42 T 09-03-2017 IPR023393 START-like domain UA74_RS19785 b5294e64d3c4b7a989fcd0c6f63cfec0 378 Pfam PF00144 Beta-lactamase 30 365 1.6E-51 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS19785 b5294e64d3c4b7a989fcd0c6f63cfec0 378 Gene3D G3DSA:3.40.710.10 238 375 3.1E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS19785 b5294e64d3c4b7a989fcd0c6f63cfec0 378 Gene3D G3DSA:3.40.710.10 9 206 3.1E-62 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS19785 b5294e64d3c4b7a989fcd0c6f63cfec0 378 SUPERFAMILY SSF56601 11 373 9.01E-57 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS17765 c07915ceacfc19fcd6de17ecf142fe78 536 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 29 484 2.0E-68 T 09-03-2017 IPR013381 CRISPR-associated protein Cse1 UA74_RS17765 c07915ceacfc19fcd6de17ecf142fe78 536 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 7 525 1.2E-40 T 09-03-2017 IPR013381 CRISPR-associated protein Cse1 UA74_RS09755 2162614e3d34f059f251afa11cb58fa0 193 SUPERFAMILY SSF50891 70 192 6.45E-41 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS09755 2162614e3d34f059f251afa11cb58fa0 193 SUPERFAMILY SSF160467 1 74 1.09E-9 T 09-03-2017 UA74_RS09755 2162614e3d34f059f251afa11cb58fa0 193 Pfam PF02682 Allophanate hydrolase subunit 1 4 181 2.4E-63 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D UA74_RS09755 2162614e3d34f059f251afa11cb58fa0 193 SMART SM00796 1 181 1.8E-78 T 09-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D UA74_RS09755 2162614e3d34f059f251afa11cb58fa0 193 Gene3D G3DSA:3.30.1360.40 8 57 3.6E-8 T 09-03-2017 IPR024946 Arginine repressor C-terminal-like domain UA74_RS09755 2162614e3d34f059f251afa11cb58fa0 193 Gene3D G3DSA:2.40.100.10 70 192 4.0E-47 T 09-03-2017 IPR029000 Cyclophilin-like domain UA74_RS23925 c94a5695f75a229a9f9686052cd8dd12 415 Pfam PF01547 Bacterial extracellular solute-binding protein 34 321 5.3E-37 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS23925 c94a5695f75a229a9f9686052cd8dd12 415 Gene3D G3DSA:3.40.190.10 29 152 1.2E-22 T 09-03-2017 UA74_RS23925 c94a5695f75a229a9f9686052cd8dd12 415 SUPERFAMILY SSF53850 11 413 4.14E-58 T 09-03-2017 UA74_RS23925 c94a5695f75a229a9f9686052cd8dd12 415 Gene3D G3DSA:3.40.190.10 153 338 1.6E-19 T 09-03-2017 UA74_RS05320 9e4faeeaedb89b2521f304a92f009927 221 Pfam PF00857 Isochorismatase family 18 168 7.3E-27 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS05320 9e4faeeaedb89b2521f304a92f009927 221 SUPERFAMILY SSF52499 11 192 5.23E-44 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS05320 9e4faeeaedb89b2521f304a92f009927 221 Gene3D G3DSA:3.40.50.850 12 198 1.8E-39 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS04315 98ce6cf4a60c99d1a6bd8cce3114df3f 356 Gene3D G3DSA:3.40.50.300 3 234 1.7E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04315 98ce6cf4a60c99d1a6bd8cce3114df3f 356 SMART SM00382 27 210 4.5E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04315 98ce6cf4a60c99d1a6bd8cce3114df3f 356 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS04315 98ce6cf4a60c99d1a6bd8cce3114df3f 356 Pfam PF00005 ABC transporter 19 160 1.5E-33 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04315 98ce6cf4a60c99d1a6bd8cce3114df3f 356 SUPERFAMILY SSF52540 4 240 3.87E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23800 bcf0a071e1929ea273dcd67aa8fd49cc 230 Gene3D G3DSA:3.30.70.1030 15 131 1.3E-24 T 09-03-2017 UA74_RS23800 bcf0a071e1929ea273dcd67aa8fd49cc 230 Pfam PF06778 Chlorite dismutase 32 220 5.3E-74 T 09-03-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase UA74_RS23800 bcf0a071e1929ea273dcd67aa8fd49cc 230 Gene3D G3DSA:3.30.70.1100 132 229 7.6E-41 T 09-03-2017 UA74_RS23800 bcf0a071e1929ea273dcd67aa8fd49cc 230 SUPERFAMILY SSF54909 5 229 9.65E-79 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS25845 0d988ff58a8c795259f16a9fe377c0e2 71 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 1 57 1.1E-15 T 09-03-2017 IPR002823 Protein of unknown function DUF112, transmembrane UA74_RS05555 f68f9541841a27b8eb538545ef36f073 574 Gene3D G3DSA:1.10.287.1060 74 125 3.0E-4 T 09-03-2017 UA74_RS05555 f68f9541841a27b8eb538545ef36f073 574 SUPERFAMILY SSF140453 75 155 7.19E-8 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS28515 ccd789a05678179f94f46ec5a0cc3714 271 SUPERFAMILY SSF50969 80 261 8.63E-11 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_RS28515 ccd789a05678179f94f46ec5a0cc3714 271 Gene3D G3DSA:2.140.10.10 43 146 1.2E-5 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain UA74_RS28515 ccd789a05678179f94f46ec5a0cc3714 271 Pfam PF05096 Glutamine cyclotransferase 32 267 2.8E-96 T 09-03-2017 IPR007788 Glutamine cyclotransferase UA74_RS26785 f845eeba3acecf1253774dbdd1b3c44b 78 Gene3D G3DSA:2.20.25.10 12 60 1.7E-11 T 09-03-2017 UA74_RS26785 f845eeba3acecf1253774dbdd1b3c44b 78 SUPERFAMILY SSF158997 6 61 3.27E-13 T 09-03-2017 UA74_RS26785 f845eeba3acecf1253774dbdd1b3c44b 78 Pfam PF03966 Trm112p-like protein 6 50 1.0E-5 T 09-03-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 UA74_RS16985 92a65df799cd80868eb13ed5c3ba8cd0 709 Pfam PF01968 Hydantoinase/oxoprolinase 194 501 3.2E-72 T 09-03-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 UA74_RS16985 92a65df799cd80868eb13ed5c3ba8cd0 709 Gene3D G3DSA:3.30.420.40 5 71 2.5E-5 T 09-03-2017 UA74_RS16985 92a65df799cd80868eb13ed5c3ba8cd0 709 SUPERFAMILY SSF53067 252 336 2.16E-12 T 09-03-2017 UA74_RS16985 92a65df799cd80868eb13ed5c3ba8cd0 709 SUPERFAMILY SSF53067 7 87 2.16E-12 T 09-03-2017 UA74_RS16985 92a65df799cd80868eb13ed5c3ba8cd0 709 SUPERFAMILY SSF53067 399 495 2.16E-12 T 09-03-2017 UA74_RS16985 92a65df799cd80868eb13ed5c3ba8cd0 709 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 7 174 6.8E-27 T 09-03-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 UA74_RS13895 40b79eb443693a57775086ed9049b7a4 297 Pfam PF05107 CRISPR-associated protein Cas7 12 281 2.9E-82 T 09-03-2017 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C UA74_RS13895 40b79eb443693a57775086ed9049b7a4 297 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 12 294 2.3E-81 T 09-03-2017 IPR013418 CRISPR-associated protein Csd2 UA74_RS13895 40b79eb443693a57775086ed9049b7a4 297 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 12 281 1.1E-61 T 09-03-2017 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C UA74_RS12905 6bc77cbbb462e45124eb2931068a98c8 103 SUPERFAMILY SSF54909 1 98 4.95E-27 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS12905 6bc77cbbb462e45124eb2931068a98c8 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 3.9E-12 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS12905 6bc77cbbb462e45124eb2931068a98c8 103 Gene3D G3DSA:3.30.70.900 1 95 5.5E-16 T 09-03-2017 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PIRSF PIRSF005536 2 685 6.0E-174 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 23 269 6.6E-38 T 09-03-2017 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 ProSitePatterns PS00512 Alpha-galactosidase signature. 340 356 - T 09-03-2017 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 389 411 3.6E-41 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 522 538 3.6E-41 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 311 325 3.6E-41 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 497 513 3.6E-41 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 339 354 3.6E-41 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 447 462 3.6E-41 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 226 241 3.6E-41 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 Pfam PF02065 Melibiase 274 612 1.7E-121 T 09-03-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 SUPERFAMILY SSF51445 307 639 5.21E-103 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS18585 7e9e7c4930ff8c1ae45cdd25ac590716 724 Gene3D G3DSA:3.20.20.70 306 596 7.7E-41 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS18225 1429bb75dc11f0b29bb9e2b179a5dc57 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS18225 1429bb75dc11f0b29bb9e2b179a5dc57 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS18225 1429bb75dc11f0b29bb9e2b179a5dc57 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-5 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS18225 1429bb75dc11f0b29bb9e2b179a5dc57 64 Pfam PF13459 4Fe-4S single cluster domain 3 62 1.6E-11 T 09-03-2017 UA74_RS18225 1429bb75dc11f0b29bb9e2b179a5dc57 64 Gene3D G3DSA:3.30.70.20 1 63 1.9E-15 T 09-03-2017 UA74_RS18225 1429bb75dc11f0b29bb9e2b179a5dc57 64 SUPERFAMILY SSF54862 2 62 3.45E-13 T 09-03-2017 UA74_RS16100 8b5ef0318301b0c3c68c758c1af64255 230 Pfam PF06508 Queuosine biosynthesis protein QueC 17 217 3.3E-42 T 09-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UA74_RS16100 8b5ef0318301b0c3c68c758c1af64255 230 Gene3D G3DSA:3.40.50.620 17 229 8.4E-47 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS16100 8b5ef0318301b0c3c68c758c1af64255 230 SUPERFAMILY SSF52402 17 227 3.53E-42 T 09-03-2017 UA74_RS16100 8b5ef0318301b0c3c68c758c1af64255 230 PIRSF PIRSF006293 14 230 3.2E-50 T 09-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UA74_RS19680 486ad0d98df600857628f429e227002c 119 Gene3D G3DSA:3.10.180.10 2 115 1.9E-9 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS19680 486ad0d98df600857628f429e227002c 119 SUPERFAMILY SSF54593 1 115 5.92E-12 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS29155 e6739b3a4961c13a97cfb8d0877b81c9 110 Pfam PF02467 Transcription factor WhiB 43 89 3.0E-11 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS07780 ee7f7dde31446a3151201ec608f83b88 277 Pfam PF12697 Alpha/beta hydrolase family 1 270 1.2E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS07780 ee7f7dde31446a3151201ec608f83b88 277 Gene3D G3DSA:3.40.50.1820 1 274 9.6E-37 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07780 ee7f7dde31446a3151201ec608f83b88 277 SUPERFAMILY SSF53474 1 273 1.85E-26 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08705 a66bfe9513ab3429c838b68f100fac57 243 SUPERFAMILY SSF53213 2 241 2.35E-8 T 09-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 UA74_RS14595 3532422950c22b65023760409ef8472e 547 Gene3D G3DSA:3.40.50.300 7 103 1.6E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14595 3532422950c22b65023760409ef8472e 547 Gene3D G3DSA:3.40.50.300 365 544 6.0E-30 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14595 3532422950c22b65023760409ef8472e 547 Gene3D G3DSA:3.40.50.300 136 279 1.6E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14595 3532422950c22b65023760409ef8472e 547 SUPERFAMILY SSF52540 361 543 4.28E-35 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14595 3532422950c22b65023760409ef8472e 547 SMART SM00382 374 541 3.6E-12 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14595 3532422950c22b65023760409ef8472e 547 SMART SM00382 29 232 2.7E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14595 3532422950c22b65023760409ef8472e 547 Pfam PF00005 ABC transporter 367 495 8.2E-16 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14595 3532422950c22b65023760409ef8472e 547 Pfam PF00005 ABC transporter 22 187 1.1E-19 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS14595 3532422950c22b65023760409ef8472e 547 SUPERFAMILY SSF52540 5 229 5.14E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25380 dae49c4b4c767feeb6610e43b60ed04d 958 Pfam PF12846 AAA-like domain 467 852 1.2E-21 T 09-03-2017 UA74_RS25380 dae49c4b4c767feeb6610e43b60ed04d 958 Gene3D G3DSA:3.40.50.300 719 797 3.4E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25380 dae49c4b4c767feeb6610e43b60ed04d 958 Gene3D G3DSA:3.40.50.300 481 551 3.4E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25380 dae49c4b4c767feeb6610e43b60ed04d 958 Gene3D G3DSA:3.40.50.300 608 656 3.4E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25380 dae49c4b4c767feeb6610e43b60ed04d 958 SUPERFAMILY SSF52540 441 557 3.19E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25380 dae49c4b4c767feeb6610e43b60ed04d 958 SUPERFAMILY SSF52540 586 803 3.19E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11395 86f4d09edf5fed6150ec2fded22c5393 182 Gene3D G3DSA:3.10.129.10 14 164 2.0E-50 T 09-03-2017 IPR029069 HotDog domain UA74_RS11395 86f4d09edf5fed6150ec2fded22c5393 182 Pfam PF03061 Thioesterase superfamily 31 102 2.4E-18 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 UA74_RS11395 86f4d09edf5fed6150ec2fded22c5393 182 SUPERFAMILY SSF54637 16 164 3.82E-41 T 09-03-2017 IPR029069 HotDog domain UA74_RS05220 5306cf2ef35a9798e1563d46a06fad43 366 SUPERFAMILY SSF55909 16 366 2.68E-101 T 09-03-2017 UA74_RS05220 5306cf2ef35a9798e1563d46a06fad43 366 Gene3D G3DSA:3.75.10.10 17 366 6.4E-136 T 09-03-2017 UA74_RS04405 27212da5482233c273785c6155b157da 595 Gene3D G3DSA:3.40.190.10 183 355 3.0E-27 T 09-03-2017 UA74_RS04405 27212da5482233c273785c6155b157da 595 SUPERFAMILY SSF53850 61 592 1.27E-75 T 09-03-2017 UA74_RS04405 27212da5482233c273785c6155b157da 595 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 512 1.6E-53 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS04405 27212da5482233c273785c6155b157da 595 Gene3D G3DSA:3.10.105.10 356 561 3.0E-38 T 09-03-2017 UA74_RS18240 209d422691110f694c3a320affb21208 284 Pfam PF01040 UbiA prenyltransferase family 31 256 3.7E-20 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 UA74_RS06130 120309ce67b54b3da4d6b853f4a9b611 142 SUPERFAMILY SSF54593 3 140 1.06E-22 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS06130 120309ce67b54b3da4d6b853f4a9b611 142 Gene3D G3DSA:3.10.180.10 1 139 4.5E-19 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS06130 120309ce67b54b3da4d6b853f4a9b611 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 136 3.4E-11 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS06130 120309ce67b54b3da4d6b853f4a9b611 142 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 09-03-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 UA74_RS00895 90affb473f8b4b6c6d202e02376a835d 323 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 1 318 7.0E-106 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS00895 90affb473f8b4b6c6d202e02376a835d 323 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 318 32.345 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS00895 90affb473f8b4b6c6d202e02376a835d 323 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 24 314 1.7E-102 T 09-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 UA74_RS00895 90affb473f8b4b6c6d202e02376a835d 323 SUPERFAMILY SSF53659 1 318 2.4E-101 T 09-03-2017 UA74_RS00895 90affb473f8b4b6c6d202e02376a835d 323 Gene3D G3DSA:3.40.718.10 1 318 6.8E-122 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 293 417 3.6E-12 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 557 687 4.0E-40 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 12 90 2.2E-12 T 09-03-2017 IPR003338 CDC48, N-terminal subdomain UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:1.10.8.60 430 503 1.7E-16 T 09-03-2017 UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:1.10.8.60 697 765 5.3E-17 T 09-03-2017 UA74_RS28740 110ab89986736c015793859d2ce080c6 781 SMART SM01073 3 91 3.1E-14 T 09-03-2017 IPR003338 CDC48, N-terminal subdomain UA74_RS28740 110ab89986736c015793859d2ce080c6 781 SUPERFAMILY SSF52540 255 504 5.27E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28740 110ab89986736c015793859d2ce080c6 781 SUPERFAMILY SSF52540 518 774 3.83E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28740 110ab89986736c015793859d2ce080c6 781 SMART SM00382 553 690 2.5E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS28740 110ab89986736c015793859d2ce080c6 781 SMART SM00382 289 423 0.0044 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:2.40.40.20 14 91 2.7E-8 T 09-03-2017 UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:3.40.50.300 518 696 5.1E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28740 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:3.40.50.300 252 429 2.1E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS28740 110ab89986736c015793859d2ce080c6 781 ProSitePatterns PS00674 AAA-protein family signature. 658 676 - T 09-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_RS28740 110ab89986736c015793859d2ce080c6 781 SUPERFAMILY SSF50692 14 89 2.36E-9 T 09-03-2017 IPR009010 Aspartate decarboxylase-like domain UA74_RS20765 08c80da44a83e11530b2f9ce5ed2c429 303 SUPERFAMILY SSF53474 83 289 3.74E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20765 08c80da44a83e11530b2f9ce5ed2c429 303 Gene3D G3DSA:3.40.50.1820 51 287 8.7E-63 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS20765 08c80da44a83e11530b2f9ce5ed2c429 303 Pfam PF01738 Dienelactone hydrolase family 97 223 3.1E-5 T 09-03-2017 IPR002925 Dienelactone hydrolase GO:0016787 UA74_RS14970 cb35562f54ca6b2e2a1cacb109bfad98 607 SMART SM00382 372 557 4.2E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS14970 cb35562f54ca6b2e2a1cacb109bfad98 607 Gene3D G3DSA:1.20.1560.10 23 327 5.4E-59 T 09-03-2017 UA74_RS14970 cb35562f54ca6b2e2a1cacb109bfad98 607 Gene3D G3DSA:3.40.50.300 347 575 9.2E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14970 cb35562f54ca6b2e2a1cacb109bfad98 607 Pfam PF00664 ABC transporter transmembrane region 33 304 7.6E-27 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS14970 cb35562f54ca6b2e2a1cacb109bfad98 607 SUPERFAMILY SSF90123 22 327 7.06E-56 T 09-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 UA74_RS14970 cb35562f54ca6b2e2a1cacb109bfad98 607 SUPERFAMILY SSF52540 341 581 5.04E-62 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14970 cb35562f54ca6b2e2a1cacb109bfad98 607 Pfam PF00005 ABC transporter 365 511 2.5E-20 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 237 248 - T 09-03-2017 IPR033116 Serine proteases, trypsin family, serine active site UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 Gene3D G3DSA:2.40.10.10 158 286 2.8E-39 T 09-03-2017 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 93 98 - T 09-03-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 Gene3D G3DSA:2.40.10.10 89 157 6.6E-15 T 09-03-2017 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 Pfam PF00089 Trypsin 56 280 1.9E-55 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 SMART SM00020 55 282 5.2E-76 T 09-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 SUPERFAMILY SSF50494 33 286 4.61E-66 T 09-03-2017 IPR009003 Peptidase S1, PA clan UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 236 248 2.2E-11 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 83 98 2.2E-11 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 147 161 2.2E-11 T 09-03-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_RS09220 009e36a9195fe2d89abdf3f7aea056ab 288 Gene3D G3DSA:2.40.10.10 56 88 1.8E-14 T 09-03-2017 UA74_RS28635 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Pfam PF08376 Nitrate and nitrite sensing 109 347 8.9E-37 T 09-03-2017 IPR013587 Nitrate/nitrite sensing protein UA74_RS28635 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 SMART SM00304 385 455 0.0026 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS28635 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 SUPERFAMILY SSF55874 554 676 2.36E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS28635 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 571 670 1.7E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS28635 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Pfam PF00672 HAMP domain 367 451 8.4E-14 T 09-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 UA74_RS28635 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 SMART SM00387 567 678 1.1E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS28635 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Gene3D G3DSA:3.30.565.10 534 672 3.7E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05630 0dc5dcc2b0b85dada5277fa4cb585580 192 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 58 189 2.6E-19 T 09-03-2017 IPR009936 Protein of unknown function DUF1468 UA74_RS10040 9bf7ef311a2ce6b0ff489411b20b8f13 228 Pfam PF02517 CAAX protease self-immunity 98 209 1.9E-14 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 UA74_RS10040 9bf7ef311a2ce6b0ff489411b20b8f13 228 PIRSF PIRSF026622 3 223 8.1E-26 T 09-03-2017 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 Gene3D G3DSA:3.30.540.10 17 163 2.1E-22 T 09-03-2017 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 Gene3D G3DSA:3.40.190.80 171 284 2.9E-10 T 09-03-2017 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 PRINTS PR00377 Inositol monophosphatase superfamily signature 200 221 9.0E-12 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 PRINTS PR00377 Inositol monophosphatase superfamily signature 154 177 9.0E-12 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 PRINTS PR00377 Inositol monophosphatase superfamily signature 105 121 9.0E-12 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 73 9.0E-12 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 PRINTS PR00377 Inositol monophosphatase superfamily signature 231 255 9.0E-12 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 Pfam PF00459 Inositol monophosphatase family 24 256 3.1E-27 T 09-03-2017 IPR000760 Inositol monophosphatase GO:0046854 UA74_RS02525 c5ecba8ed186518b9277c60e571c1eb4 289 SUPERFAMILY SSF56655 18 283 4.06E-35 T 09-03-2017 UA74_RS18985 4b550ad6bfcaa59ef4714ef5f82106c4 191 Pfam PF03358 NADPH-dependent FMN reductase 5 145 7.9E-30 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS18985 4b550ad6bfcaa59ef4714ef5f82106c4 191 SUPERFAMILY SSF52218 4 174 1.02E-35 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS18985 4b550ad6bfcaa59ef4714ef5f82106c4 191 Gene3D G3DSA:3.40.50.360 6 182 3.3E-45 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 8 357 1.3E-207 T 09-03-2017 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 SUPERFAMILY SSF55347 194 302 1.57E-34 T 09-03-2017 UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 Pfam PF01658 Myo-inositol-1-phosphate synthase 195 303 2.2E-31 T 09-03-2017 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 Gene3D G3DSA:3.30.360.10 194 303 6.5E-48 T 09-03-2017 UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 PIRSF PIRSF015578 2 359 1.1E-93 T 09-03-2017 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 SUPERFAMILY SSF51735 7 189 1.41E-93 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 SUPERFAMILY SSF51735 300 359 1.41E-93 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 Gene3D G3DSA:3.40.50.720 304 358 2.5E-115 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30130 49547537de501e07100cf5d3d0bc5ba6 363 Gene3D G3DSA:3.40.50.720 5 193 2.5E-115 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS30215 a394c524239c8296e0b58555d3e27136 348 Pfam PF13411 MerR HTH family regulatory protein 10 78 2.0E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS30215 a394c524239c8296e0b58555d3e27136 348 SUPERFAMILY SSF46955 10 113 4.76E-24 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS30215 a394c524239c8296e0b58555d3e27136 348 SMART SM00422 10 79 1.5E-17 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS30215 a394c524239c8296e0b58555d3e27136 348 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 2.3E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS30215 a394c524239c8296e0b58555d3e27136 348 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 2.3E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS30215 a394c524239c8296e0b58555d3e27136 348 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 2.3E-8 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS30215 a394c524239c8296e0b58555d3e27136 348 Gene3D G3DSA:1.10.1660.10 10 114 1.1E-27 T 09-03-2017 UA74_RS28725 00b3ac6664ab225305efb3bcb6b0421e 212 SUPERFAMILY SSF51219 4 209 9.16E-30 T 09-03-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain UA74_RS28725 00b3ac6664ab225305efb3bcb6b0421e 212 Gene3D G3DSA:3.60.160.10 6 209 3.2E-29 T 09-03-2017 IPR002838 Mitochondrial biogenesis protein AIM24 UA74_RS28725 00b3ac6664ab225305efb3bcb6b0421e 212 Pfam PF01987 Mitochondrial biogenesis AIM24 10 205 1.7E-28 T 09-03-2017 IPR002838 Mitochondrial biogenesis protein AIM24 UA74_RS25995 43bb9971b9881024335cca13dd388c38 165 SUPERFAMILY SSF51182 25 152 1.1E-29 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS25995 43bb9971b9881024335cca13dd388c38 165 Pfam PF05995 Cysteine dioxygenase type I 27 150 1.7E-23 T 09-03-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 UA74_RS25995 43bb9971b9881024335cca13dd388c38 165 Gene3D G3DSA:2.60.120.10 34 156 1.9E-20 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS27320 5c6f16d52ea2bb3a7dbd1f8a11a412f4 284 Pfam PF13460 NAD(P)H-binding 14 115 1.5E-6 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27320 5c6f16d52ea2bb3a7dbd1f8a11a412f4 284 SUPERFAMILY SSF51735 8 275 4.24E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27320 5c6f16d52ea2bb3a7dbd1f8a11a412f4 284 Gene3D G3DSA:3.40.50.720 9 217 3.4E-23 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13785 10004d11cf49630fa8b6885f34019b75 198 SUPERFAMILY SSF52540 16 191 2.52E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13785 10004d11cf49630fa8b6885f34019b75 198 Pfam PF03029 Conserved hypothetical ATP binding protein 21 164 2.5E-24 T 09-03-2017 IPR004130 GPN-loop GTPase UA74_RS13785 10004d11cf49630fa8b6885f34019b75 198 Gene3D G3DSA:3.40.50.300 16 184 6.7E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS14955 cb0a92006d5e6c269a63ebfe59fb6721 302 PIRSF PIRSF000103 6 302 1.7E-41 T 09-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_RS14955 cb0a92006d5e6c269a63ebfe59fb6721 302 SUPERFAMILY SSF51735 14 164 2.35E-30 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14955 cb0a92006d5e6c269a63ebfe59fb6721 302 SUPERFAMILY SSF48179 183 297 1.25E-5 T 09-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 UA74_RS14955 cb0a92006d5e6c269a63ebfe59fb6721 302 Gene3D G3DSA:1.10.1040.10 187 297 4.4E-5 T 09-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_RS14955 cb0a92006d5e6c269a63ebfe59fb6721 302 Gene3D G3DSA:3.40.50.720 7 169 1.3E-29 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14955 cb0a92006d5e6c269a63ebfe59fb6721 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 165 2.9E-20 T 09-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 UA74_RS28960 baee57ab1d8da39702198e7e1aff9f6f 283 Pfam PF00535 Glycosyl transferase family 2 66 182 3.0E-20 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS28960 baee57ab1d8da39702198e7e1aff9f6f 283 Gene3D G3DSA:3.90.550.10 64 261 8.6E-33 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS28960 baee57ab1d8da39702198e7e1aff9f6f 283 SUPERFAMILY SSF53448 64 263 3.38E-33 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS11820 f65c2f5b43f2eb063754db4ff501ac61 139 Pfam PF13581 Histidine kinase-like ATPase domain 18 85 3.3E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS19630 04806bda3711713adbe64164c907043f 320 Gene3D G3DSA:1.10.3720.10 87 318 6.6E-63 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19630 04806bda3711713adbe64164c907043f 320 SUPERFAMILY SSF161098 81 308 1.14E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19630 04806bda3711713adbe64164c907043f 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 316 3.5E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18695 1c5cb26e5295d3f901eace3289312215 653 Gene3D G3DSA:2.130.10.130 403 541 1.5E-25 T 09-03-2017 UA74_RS18695 1c5cb26e5295d3f901eace3289312215 653 Gene3D G3DSA:2.130.10.130 78 369 1.5E-25 T 09-03-2017 UA74_RS18695 1c5cb26e5295d3f901eace3289312215 653 Pfam PF07593 ASPIC and UnbV 573 631 1.1E-7 T 09-03-2017 IPR011519 ASPIC/UnbV UA74_RS18695 1c5cb26e5295d3f901eace3289312215 653 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 294 368 8.1E-7 T 09-03-2017 UA74_RS18695 1c5cb26e5295d3f901eace3289312215 653 SUPERFAMILY SSF69318 70 442 1.57E-50 T 09-03-2017 UA74_RS18695 1c5cb26e5295d3f901eace3289312215 653 SUPERFAMILY SSF69318 477 539 1.57E-50 T 09-03-2017 UA74_RS26960 03719c1df8b809ba5bebe80ec51b02ef 193 Pfam PF13707 RloB-like protein 14 150 1.6E-29 T 09-03-2017 IPR025591 RloB-like protein UA74_RS26010 d60f10518c78140b7fc2ef52c2d8d809 249 Pfam PF01553 Acyltransferase 31 157 7.2E-27 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS26010 d60f10518c78140b7fc2ef52c2d8d809 249 SUPERFAMILY SSF69593 29 225 5.75E-45 T 09-03-2017 UA74_RS26010 d60f10518c78140b7fc2ef52c2d8d809 249 Gene3D G3DSA:3.40.1130.10 30 223 1.8E-24 T 09-03-2017 UA74_RS26010 d60f10518c78140b7fc2ef52c2d8d809 249 SMART SM00563 43 161 7.0E-34 T 09-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 UA74_RS23830 f63966c44ba19dd23ac7721d80404f59 92 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 67 2.9E-5 T 09-03-2017 IPR027379 Cardiolipin synthase N-terminal UA74_RS16560 95481c8da00478c1be0cfa8673809483 269 Pfam PF01061 ABC-2 type transporter 18 233 1.1E-32 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS16560 95481c8da00478c1be0cfa8673809483 269 PIRSF PIRSF006648 3 269 1.9E-58 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 SUPERFAMILY SSF51735 2 238 1.15E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 Gene3D G3DSA:3.40.50.720 2 238 2.4E-54 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 236 8.8E-40 T 09-03-2017 UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 5.2E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 5.2E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.2E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 5.2E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 5.2E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22095 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.2E-19 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14325 bdae360972f99a2c094d88db3d4ce5d6 218 Gene3D G3DSA:3.40.225.10 4 212 8.6E-52 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS14325 bdae360972f99a2c094d88db3d4ce5d6 218 SUPERFAMILY SSF53639 4 213 2.94E-50 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS14325 bdae360972f99a2c094d88db3d4ce5d6 218 SMART SM01007 6 188 1.4E-48 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS14325 bdae360972f99a2c094d88db3d4ce5d6 218 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 187 6.1E-41 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 Gene3D G3DSA:1.25.40.10 495 700 1.3E-17 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 SUPERFAMILY SSF52540 46 319 2.02E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 SUPERFAMILY SSF48452 493 697 1.65E-16 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 Gene3D G3DSA:3.40.50.300 69 205 9.9E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 PRINTS PR00364 Disease resistance protein signature 253 267 5.4E-11 T 09-03-2017 UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 PRINTS PR00364 Disease resistance protein signature 89 104 5.4E-11 T 09-03-2017 UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 PRINTS PR00364 Disease resistance protein signature 166 180 5.4E-11 T 09-03-2017 UA74_RS21430 48b0700eda48027fe93441b84d65979c 733 Pfam PF00931 NB-ARC domain 85 311 1.6E-9 T 09-03-2017 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6803207 UA74_RS23435 a1a84ff1251c3b0f08e21f4639bed5a4 109 Pfam PF14079 Domain of unknown function (DUF4260) 4 104 3.1E-28 T 09-03-2017 IPR025356 Protein of unknown function DUF4260 UA74_RS23235 a290e4764822d8ee673118701b04b294 216 Gene3D G3DSA:1.10.3630.10 8 209 5.2E-13 T 09-03-2017 UA74_RS23235 a290e4764822d8ee673118701b04b294 216 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 7 203 3.8E-31 T 09-03-2017 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 UA74_RS08480 4212c664e7d2c5043ced7b762ef183c4 448 Pfam PF03631 Virulence factor BrkB 36 296 3.0E-43 T 09-03-2017 IPR017039 Virulence factor BrkB UA74_RS24540 3af5ec15ff5de560df7c5b26913a2c35 246 PIRSF PIRSF006648 2 245 1.5E-19 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS24540 3af5ec15ff5de560df7c5b26913a2c35 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 6.0E-5 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS24540 3af5ec15ff5de560df7c5b26913a2c35 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 6.0E-5 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS24540 3af5ec15ff5de560df7c5b26913a2c35 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 6.0E-5 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS24540 3af5ec15ff5de560df7c5b26913a2c35 246 Pfam PF01061 ABC-2 type transporter 3 213 2.8E-27 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS23680 3143d199e409d3fe0e5a97c091d27a1a 385 SUPERFAMILY SSF51445 14 384 7.72E-68 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS23680 3143d199e409d3fe0e5a97c091d27a1a 385 Gene3D G3DSA:3.20.20.80 14 384 1.2E-59 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS23680 3143d199e409d3fe0e5a97c091d27a1a 385 Pfam PF00232 Glycosyl hydrolase family 1 15 244 7.2E-31 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS23680 3143d199e409d3fe0e5a97c091d27a1a 385 Pfam PF00232 Glycosyl hydrolase family 1 314 381 5.7E-7 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 Gene3D G3DSA:3.50.50.60 1 168 8.9E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 Gene3D G3DSA:3.50.50.60 333 433 8.9E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 Gene3D G3DSA:3.50.50.60 169 302 1.1E-6 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 SUPERFAMILY SSF51905 1 194 1.0E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 PIRSF PIRSF000332 1 431 4.3E-52 T 09-03-2017 IPR012143 Dimethylaniline monooxygenase, N-oxide-forming GO:0004499|GO:0050660|GO:0050661|GO:0055114 KEGG: 00982+1.14.13.8 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 287 314 6.8E-10 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 21 45 6.8E-10 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 176 191 6.8E-10 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 149 163 6.8E-10 T 09-03-2017 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 Pfam PF00743 Flavin-binding monooxygenase-like 1 373 1.5E-46 T 09-03-2017 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_RS16775 e2e824cb439e33bc582b37ea0d99804c 439 SUPERFAMILY SSF51905 141 303 8.33E-16 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS02510 a677a95147acf84783005c707a500920 169 SUPERFAMILY SSF117916 2 98 3.6E-23 T 09-03-2017 UA74_RS02510 a677a95147acf84783005c707a500920 169 Pfam PF01883 Domain of unknown function DUF59 7 72 3.4E-13 T 09-03-2017 IPR002744 Domain of unknown function DUF59 UA74_RS02510 a677a95147acf84783005c707a500920 169 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 16 168 2.7E-55 T 09-03-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit UA74_RS04680 a3b826d0be536fd8d1ab7671026ae502 282 Gene3D G3DSA:3.90.1530.10 84 147 7.7E-5 T 09-03-2017 UA74_RS04680 a3b826d0be536fd8d1ab7671026ae502 282 SUPERFAMILY SSF110849 90 146 9.42E-9 T 09-03-2017 IPR003115 ParB/Sulfiredoxin UA74_RS05870 11fb4fea7a1da7384e5b72833bdd0a27 392 Gene3D G3DSA:3.40.1710.10 50 144 1.2E-4 T 09-03-2017 UA74_RS05870 11fb4fea7a1da7384e5b72833bdd0a27 392 Pfam PF12698 ABC-2 family transporter protein 24 384 2.1E-30 T 09-03-2017 UA74_RS05335 25a169e64adb12fe2be93e17ddbe3139 395 Pfam PF07730 Histidine kinase 192 256 4.5E-17 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS05335 25a169e64adb12fe2be93e17ddbe3139 395 Gene3D G3DSA:3.30.565.10 304 386 7.3E-4 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05335 25a169e64adb12fe2be93e17ddbe3139 395 SUPERFAMILY SSF55874 282 390 2.15E-11 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08345 e78e778af2a48a9f2dc147d4951ee2aa 74 SUPERFAMILY SSF54862 4 63 4.02E-9 T 09-03-2017 UA74_RS08345 e78e778af2a48a9f2dc147d4951ee2aa 74 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 4.0E-6 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS08345 e78e778af2a48a9f2dc147d4951ee2aa 74 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 4.0E-6 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS08345 e78e778af2a48a9f2dc147d4951ee2aa 74 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 4.0E-6 T 09-03-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_RS08345 e78e778af2a48a9f2dc147d4951ee2aa 74 Gene3D G3DSA:3.30.70.20 4 64 5.6E-14 T 09-03-2017 UA74_RS08345 e78e778af2a48a9f2dc147d4951ee2aa 74 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 59 7.0E-10 T 09-03-2017 UA74_RS26780 006fc6134fdf9bcec16c770e9e9c4f44 367 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 203 354 5.7E-9 T 09-03-2017 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 UA74_RS26780 006fc6134fdf9bcec16c770e9e9c4f44 367 SUPERFAMILY SSF53697 68 354 7.78E-43 T 09-03-2017 UA74_RS09045 a79dac5f314329fd78f3ecb597e2a757 250 SUPERFAMILY SSF53633 11 241 6.02E-69 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS09045 a79dac5f314329fd78f3ecb597e2a757 250 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 12 242 6.6E-88 T 09-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 UA74_RS09045 a79dac5f314329fd78f3ecb597e2a757 250 PIRSF PIRSF005650 7 249 1.0E-86 T 09-03-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 UA74_RS09045 a79dac5f314329fd78f3ecb597e2a757 250 Gene3D G3DSA:3.40.1160.10 4 242 1.6E-85 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS09045 a79dac5f314329fd78f3ecb597e2a757 250 Pfam PF00696 Amino acid kinase family 13 221 5.1E-28 T 09-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase UA74_RS09045 a79dac5f314329fd78f3ecb597e2a757 250 Hamap MF_01220_B Uridylate kinase [pyrH]. 9 242 42.621 T 09-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 UA74_RS04740 30a32619106a530755539c6593c389cb 402 Gene3D G3DSA:2.140.10.10 69 118 3.0E-8 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain UA74_RS04740 30a32619106a530755539c6593c389cb 402 Gene3D G3DSA:2.140.10.10 184 185 3.0E-8 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain UA74_RS04740 30a32619106a530755539c6593c389cb 402 Gene3D G3DSA:2.140.10.10 296 382 3.0E-8 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain UA74_RS04740 30a32619106a530755539c6593c389cb 402 SUPERFAMILY SSF50998 58 175 1.67E-6 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_RS04740 30a32619106a530755539c6593c389cb 402 SUPERFAMILY SSF50998 213 231 1.67E-6 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_RS04740 30a32619106a530755539c6593c389cb 402 SUPERFAMILY SSF50998 298 372 1.67E-6 T 09-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_RS04740 30a32619106a530755539c6593c389cb 402 Pfam PF13360 PQQ-like domain 290 374 2.5E-4 T 09-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat UA74_RS25340 38817a5662f01992c6e60fb55c4eaf04 294 SUPERFAMILY SSF53807 17 265 1.96E-25 T 09-03-2017 UA74_RS25340 38817a5662f01992c6e60fb55c4eaf04 294 Gene3D G3DSA:3.40.50.1980 17 117 9.5E-17 T 09-03-2017 UA74_RS25340 38817a5662f01992c6e60fb55c4eaf04 294 Gene3D G3DSA:3.40.50.1980 144 181 0.001 T 09-03-2017 UA74_RS10925 537780f48b961fd38dc8cddfb7445b5d 310 SUPERFAMILY SSF51735 9 299 4.35E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10925 537780f48b961fd38dc8cddfb7445b5d 310 Pfam PF00106 short chain dehydrogenase 16 216 1.4E-26 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10925 537780f48b961fd38dc8cddfb7445b5d 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 3.9E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10925 537780f48b961fd38dc8cddfb7445b5d 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.9E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10925 537780f48b961fd38dc8cddfb7445b5d 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.9E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10925 537780f48b961fd38dc8cddfb7445b5d 310 Gene3D G3DSA:3.40.50.720 6 242 7.8E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10925 537780f48b961fd38dc8cddfb7445b5d 310 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 161 0.0041 T 09-03-2017 UA74_RS16920 6cb53e265c0f5853684d7d3876964143 295 SUPERFAMILY SSF47413 31 82 2.62E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16920 6cb53e265c0f5853684d7d3876964143 295 Gene3D G3DSA:1.10.260.40 3 82 4.8E-19 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16920 6cb53e265c0f5853684d7d3876964143 295 Pfam PF13560 Helix-turn-helix domain 6 86 6.3E-16 T 09-03-2017 UA74_RS16920 6cb53e265c0f5853684d7d3876964143 295 SMART SM00530 10 83 7.8E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS12105 599391a0663762b4f421351bb9930bb7 435 Gene3D G3DSA:3.50.50.60 3 200 1.3E-14 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12105 599391a0663762b4f421351bb9930bb7 435 Gene3D G3DSA:3.50.50.60 201 233 3.6E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12105 599391a0663762b4f421351bb9930bb7 435 Gene3D G3DSA:3.50.50.60 269 366 3.6E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12105 599391a0663762b4f421351bb9930bb7 435 SUPERFAMILY SSF51905 273 369 6.09E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12105 599391a0663762b4f421351bb9930bb7 435 SUPERFAMILY SSF51905 186 212 6.09E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12105 599391a0663762b4f421351bb9930bb7 435 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 341 7.6E-103 T 09-03-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase UA74_RS12105 599391a0663762b4f421351bb9930bb7 435 SUPERFAMILY SSF51905 4 270 1.15E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS00380 9135b816944fa9950ffc3070062dc217 115 SMART SM00450 9 103 6.5E-24 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS00380 9135b816944fa9950ffc3070062dc217 115 SUPERFAMILY SSF52821 5 106 1.15E-32 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS00380 9135b816944fa9950ffc3070062dc217 115 Pfam PF00581 Rhodanese-like domain 19 99 3.6E-15 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS00380 9135b816944fa9950ffc3070062dc217 115 Gene3D G3DSA:3.40.250.10 6 107 5.3E-32 T 09-03-2017 IPR001763 Rhodanese-like domain UA74_RS16750 672869c75dd87e4b13805f0761647041 51 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 51 4.8E-13 T 09-03-2017 IPR025161 Putative transposase IS4/IS5 family UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 38 56 1.1E-10 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.1E-10 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 261 283 1.1E-10 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 228 244 1.1E-10 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 Gene3D G3DSA:3.40.50.1820 3 285 2.9E-53 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 Pfam PF00561 alpha/beta hydrolase fold 30 269 2.8E-22 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 SUPERFAMILY SSF53474 4 285 1.63E-53 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.5E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.5E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.5E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS24240 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.5E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS04575 2908b8b3f8a909678d1e061bff807745 257 SUPERFAMILY SSF52096 2 256 2.73E-80 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS04575 2908b8b3f8a909678d1e061bff807745 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 5 255 3.5E-63 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 UA74_RS04575 2908b8b3f8a909678d1e061bff807745 257 Gene3D G3DSA:3.90.226.10 2 197 1.4E-63 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS04575 2908b8b3f8a909678d1e061bff807745 257 Gene3D G3DSA:1.10.12.10 199 257 1.4E-17 T 09-03-2017 IPR014748 Crontonase, C-terminal UA74_RS18655 fc1f37935f4532a0a6891b4c3d66d101 267 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 4.9E-36 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_RS18655 fc1f37935f4532a0a6891b4c3d66d101 267 SUPERFAMILY SSF109854 3 153 1.7E-22 T 09-03-2017 UA74_RS18655 fc1f37935f4532a0a6891b4c3d66d101 267 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 147 9.7E-22 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_RS18655 fc1f37935f4532a0a6891b4c3d66d101 267 Gene3D G3DSA:1.20.120.450 3 117 7.6E-8 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS18655 fc1f37935f4532a0a6891b4c3d66d101 267 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 6 257 9.8E-94 T 09-03-2017 IPR017518 Conserved hypothetical protein CHP03084 UA74_RS19790 59c785a699ef579529b91c181328665f 153 Gene3D G3DSA:3.30.530.20 9 147 1.3E-28 T 09-03-2017 IPR023393 START-like domain UA74_RS19790 59c785a699ef579529b91c181328665f 153 SUPERFAMILY SSF55961 10 146 2.85E-28 T 09-03-2017 UA74_RS19790 59c785a699ef579529b91c181328665f 153 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 147 1.6E-20 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS29195 2d9ea4448d3b988ae255ef1262edb275 399 Gene3D G3DSA:1.25.40.10 148 282 5.4E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS29195 2d9ea4448d3b988ae255ef1262edb275 399 SUPERFAMILY SSF48452 177 285 4.01E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS28945 72f4431ea853c075b043d594b692283e 396 SUPERFAMILY SSF53756 2 80 3.24E-12 T 09-03-2017 UA74_RS28945 72f4431ea853c075b043d594b692283e 396 SUPERFAMILY SSF53756 120 371 3.24E-12 T 09-03-2017 UA74_RS28945 72f4431ea853c075b043d594b692283e 396 Pfam PF13692 Glycosyl transferases group 1 241 368 2.7E-10 T 09-03-2017 UA74_RS28945 72f4431ea853c075b043d594b692283e 396 Pfam PF13579 Glycosyl transferase 4-like domain 17 224 7.2E-9 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.3E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.3E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.3E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 6.7E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.7E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.7E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.7E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.7E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.7E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 4.6E-45 T 09-03-2017 UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 Gene3D G3DSA:3.40.50.720 2 258 3.3E-64 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14580 fa5658768e1d304c468265b7c20f2fc0 262 SUPERFAMILY SSF51735 7 258 3.42E-62 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10315 6b302cc520edc29f6da897169512eb3e 394 SUPERFAMILY SSF116734 2 153 1.49E-23 T 09-03-2017 UA74_RS10315 6b302cc520edc29f6da897169512eb3e 394 SUPERFAMILY SSF116734 188 381 2.45E-19 T 09-03-2017 UA74_RS10315 6b302cc520edc29f6da897169512eb3e 394 Pfam PF01420 Type I restriction modification DNA specificity domain 32 139 2.4E-5 T 09-03-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 UA74_RS28880 0df9448dbac523ea3e597991e10e1797 163 Gene3D G3DSA:3.30.530.20 3 162 1.8E-38 T 09-03-2017 IPR023393 START-like domain UA74_RS28880 0df9448dbac523ea3e597991e10e1797 163 SUPERFAMILY SSF55961 3 147 7.74E-34 T 09-03-2017 UA74_RS28880 0df9448dbac523ea3e597991e10e1797 163 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 141 3.0E-15 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 250 3.1E-61 T 09-03-2017 UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 Gene3D G3DSA:3.40.50.720 1 249 5.8E-79 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.9E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.9E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.9E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.9E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.9E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.9E-35 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 SUPERFAMILY SSF51735 6 249 1.83E-76 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.2E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS11100 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.2E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07915 c7d335a06799da5c43d8f4769818dced 138 Gene3D G3DSA:3.40.50.720 7 115 3.6E-15 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07915 c7d335a06799da5c43d8f4769818dced 138 SUPERFAMILY SSF51735 1 115 2.99E-16 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 Gene3D G3DSA:3.40.50.720 13 151 2.0E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 PIRSF PIRSF000148 11 361 8.9E-108 T 09-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 SUPERFAMILY SSF55347 138 346 9.55E-66 T 09-03-2017 UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 150 345 1.9E-45 T 09-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 14 360 1.2E-115 T 09-03-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 14 127 3.2E-27 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 SUPERFAMILY SSF51735 13 165 2.45E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 Gene3D G3DSA:3.30.360.10 152 341 2.2E-70 T 09-03-2017 UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 SMART SM00859 13 129 1.1E-35 T 09-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_RS01075 67256d2c56fb13fb2b5f8d69abe66a28 361 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 11 359 32.371 T 09-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 UA74_RS28875 7646cf4793d7498ad21fa88c7e94b314 130 Pfam PF01638 HxlR-like helix-turn-helix 33 121 2.3E-33 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS28875 7646cf4793d7498ad21fa88c7e94b314 130 Gene3D G3DSA:1.10.10.10 24 126 2.3E-43 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28875 7646cf4793d7498ad21fa88c7e94b314 130 SUPERFAMILY SSF46785 23 122 1.65E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:3.40.50.300 491 556 2.3E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:3.40.50.300 18 59 7.2E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:3.40.50.300 106 107 7.2E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:3.40.50.300 367 482 7.2E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:3.40.50.300 683 796 2.3E-54 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Pfam PF00005 ABC transporter 507 719 2.4E-10 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:1.20.1580.10 301 366 6.3E-29 T 09-03-2017 UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:1.20.1580.10 111 186 6.3E-29 T 09-03-2017 UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 SUPERFAMILY SSF52540 23 70 1.9E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 SUPERFAMILY SSF52540 313 459 1.9E-31 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:1.10.8.280 189 300 1.6E-9 T 09-03-2017 UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:1.20.1580.10 560 682 1.5E-35 T 09-03-2017 UA74_RS07590 48e98221a46861e65114cd0890032cc7 801 SUPERFAMILY SSF52540 500 772 6.55E-37 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01610 5583a0afe025b88b34ebef6718f36d42 103 Gene3D G3DSA:3.30.70.900 1 100 3.8E-34 T 09-03-2017 UA74_RS01610 5583a0afe025b88b34ebef6718f36d42 103 SUPERFAMILY SSF54909 1 96 1.86E-24 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS01610 5583a0afe025b88b34ebef6718f36d42 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 73 5.6E-19 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS08400 ee3554778ca23c1371bdd7b23a814584 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 245 3.6E-35 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_RS17400 731e092651bdcf54b7fb8814c4c28c16 301 Pfam PF12697 Alpha/beta hydrolase family 75 262 6.2E-9 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS17400 731e092651bdcf54b7fb8814c4c28c16 301 SUPERFAMILY SSF53474 38 280 8.26E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17400 731e092651bdcf54b7fb8814c4c28c16 301 Gene3D G3DSA:3.40.50.1820 69 279 1.7E-26 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS11705 c9aa656cad8533e8ae403f0914af3ffe 238 PIRSF PIRSF015736 3 237 2.2E-49 T 09-03-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_RS09565 c3b8de514c9e01304b9528f62bc02b6f 250 SUPERFAMILY SSF69796 32 234 4.58E-60 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS09565 c3b8de514c9e01304b9528f62bc02b6f 250 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 7 238 25.963 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS09565 c3b8de514c9e01304b9528f62bc02b6f 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 8 230 4.2E-59 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS09565 c3b8de514c9e01304b9528f62bc02b6f 250 Pfam PF02511 Thymidylate synthase complementing protein 31 225 1.9E-53 T 09-03-2017 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_RS28000 9147263c31c8437b40aee7a9770e1a8c 485 Pfam PF04024 PspC domain 33 84 8.7E-11 T 09-03-2017 IPR007168 Phage shock protein, PspC, N-terminal UA74_RS28000 9147263c31c8437b40aee7a9770e1a8c 485 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 391 482 1.5E-7 T 09-03-2017 IPR024425 Cell wall-active antibiotics response 4TMS YvqF UA74_RS05385 1016c60cb20d3d1298109e527d8340bb 302 Pfam PF12697 Alpha/beta hydrolase family 42 292 3.0E-16 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS05385 1016c60cb20d3d1298109e527d8340bb 302 Gene3D G3DSA:3.40.50.1820 16 296 3.0E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS05385 1016c60cb20d3d1298109e527d8340bb 302 SUPERFAMILY SSF53474 12 296 8.03E-35 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06780 dacd6539be9b1b37f63e9a08b4fd22a2 447 SUPERFAMILY SSF56801 41 440 1.96E-69 T 09-03-2017 UA74_RS06780 dacd6539be9b1b37f63e9a08b4fd22a2 447 Gene3D G3DSA:3.40.50.980 56 208 1.2E-18 T 09-03-2017 UA74_RS06780 dacd6539be9b1b37f63e9a08b4fd22a2 447 Gene3D G3DSA:3.40.50.980 231 356 6.6E-31 T 09-03-2017 UA74_RS06780 dacd6539be9b1b37f63e9a08b4fd22a2 447 Pfam PF00501 AMP-binding enzyme 56 435 1.5E-54 T 09-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 UA74_RS06780 dacd6539be9b1b37f63e9a08b4fd22a2 447 Gene3D G3DSA:2.30.38.10 362 434 6.5E-9 T 09-03-2017 UA74_RS22215 f8edac354f748fc9d0ab720770b9151e 218 SUPERFAMILY SSF52266 15 200 5.04E-38 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS22215 f8edac354f748fc9d0ab720770b9151e 218 Gene3D G3DSA:3.40.50.1110 16 200 7.3E-36 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS22215 f8edac354f748fc9d0ab720770b9151e 218 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 21 190 3.2E-29 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS05560 dd17e85c46812d17e7bd4474b90314bb 565 Gene3D G3DSA:1.10.287.1060 61 140 9.9E-4 T 09-03-2017 UA74_RS05560 dd17e85c46812d17e7bd4474b90314bb 565 SUPERFAMILY SSF140453 62 149 7.98E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS14100 173830c8001bf373076c7fc3f8ae7e69 654 Gene3D G3DSA:2.120.10.30 83 358 2.5E-10 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS14100 173830c8001bf373076c7fc3f8ae7e69 654 Gene3D G3DSA:3.40.50.1820 359 640 3.6E-66 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14100 173830c8001bf373076c7fc3f8ae7e69 654 Pfam PF00326 Prolyl oligopeptidase family 437 641 1.8E-46 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS14100 173830c8001bf373076c7fc3f8ae7e69 654 SUPERFAMILY SSF82171 79 368 3.92E-12 T 09-03-2017 UA74_RS14100 173830c8001bf373076c7fc3f8ae7e69 654 SUPERFAMILY SSF53474 385 640 1.35E-59 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS09300 cfb1f30d386689a50d59954a966a3e5f 343 Gene3D G3DSA:3.90.1150.10 275 341 9.9E-5 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS09300 cfb1f30d386689a50d59954a966a3e5f 343 SUPERFAMILY SSF53383 14 342 1.21E-39 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS09300 cfb1f30d386689a50d59954a966a3e5f 343 Pfam PF00266 Aminotransferase class-V 20 290 7.5E-8 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS09300 cfb1f30d386689a50d59954a966a3e5f 343 Gene3D G3DSA:3.40.640.10 31 226 1.9E-25 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS20410 f5f4fe4311ee7db058d72b54c3004648 439 SUPERFAMILY SSF50939 78 426 1.51E-63 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS20410 f5f4fe4311ee7db058d72b54c3004648 439 Gene3D G3DSA:2.120.10.10 50 426 4.4E-60 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS20410 f5f4fe4311ee7db058d72b54c3004648 439 Pfam PF13088 BNR repeat-like domain 96 394 7.5E-22 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS11720 e3a611505a09c22b95be4ed2c3c32b75 417 Gene3D G3DSA:3.40.640.10 48 297 2.2E-89 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS11720 e3a611505a09c22b95be4ed2c3c32b75 417 Gene3D G3DSA:3.90.1150.10 298 414 1.2E-43 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS11720 e3a611505a09c22b95be4ed2c3c32b75 417 SUPERFAMILY SSF53383 11 412 4.03E-134 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS11720 e3a611505a09c22b95be4ed2c3c32b75 417 Pfam PF00202 Aminotransferase class-III 12 412 1.7E-123 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS11720 e3a611505a09c22b95be4ed2c3c32b75 417 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS01505 320c2a1a30635c17ffd9c2a74ec9340f 337 Pfam PF01171 PP-loop family 19 192 3.3E-31 T 09-03-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 UA74_RS01505 320c2a1a30635c17ffd9c2a74ec9340f 337 SUPERFAMILY SSF82829 205 307 1.26E-13 T 09-03-2017 UA74_RS01505 320c2a1a30635c17ffd9c2a74ec9340f 337 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 302 18.49 T 09-03-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UA74_RS01505 320c2a1a30635c17ffd9c2a74ec9340f 337 Gene3D G3DSA:3.40.50.620 19 137 1.3E-6 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS01505 320c2a1a30635c17ffd9c2a74ec9340f 337 Pfam PF09179 TilS substrate binding domain 243 308 2.8E-12 T 09-03-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UA74_RS01505 320c2a1a30635c17ffd9c2a74ec9340f 337 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 19 195 2.4E-37 T 09-03-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UA74_RS01505 320c2a1a30635c17ffd9c2a74ec9340f 337 SUPERFAMILY SSF52402 19 224 1.12E-42 T 09-03-2017 UA74_RS13685 4e72bce5cd779550718a471c78d5181e 463 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 264 275 - T 09-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 UA74_RS13685 4e72bce5cd779550718a471c78d5181e 463 SUPERFAMILY SSF53720 2 461 4.97E-152 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS13685 4e72bce5cd779550718a471c78d5181e 463 Pfam PF00171 Aldehyde dehydrogenase family 6 461 1.2E-159 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS13685 4e72bce5cd779550718a471c78d5181e 463 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 236 243 - T 09-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 UA74_RS13685 4e72bce5cd779550718a471c78d5181e 463 Gene3D G3DSA:3.40.605.10 2 248 8.9E-83 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS13685 4e72bce5cd779550718a471c78d5181e 463 Gene3D G3DSA:3.40.309.10 249 436 4.6E-63 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS04665 3e12285a4ce3a9c614eb599614bd3114 322 Gene3D G3DSA:1.10.3720.10 34 306 2.2E-51 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04665 3e12285a4ce3a9c614eb599614bd3114 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 309 5.1E-10 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04665 3e12285a4ce3a9c614eb599614bd3114 322 SUPERFAMILY SSF161098 37 311 4.58E-48 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS11165 3032acea31975d3b4957a188eac25d11 146 Pfam PF02699 Preprotein translocase subunit 5 80 3.1E-21 T 09-03-2017 IPR003849 Preprotein translocase YajC UA74_RS11165 3032acea31975d3b4957a188eac25d11 146 SMART SM01323 1 83 5.7E-29 T 09-03-2017 IPR003849 Preprotein translocase YajC UA74_RS11165 3032acea31975d3b4957a188eac25d11 146 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 82 3.6E-22 T 09-03-2017 IPR003849 Preprotein translocase YajC UA74_RS14800 a192401c05cac418f531fbd36d366ac8 249 Gene3D G3DSA:3.40.50.150 203 236 1.2E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14800 a192401c05cac418f531fbd36d366ac8 249 Gene3D G3DSA:3.40.50.150 21 167 1.2E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14800 a192401c05cac418f531fbd36d366ac8 249 SUPERFAMILY SSF53335 21 163 1.66E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14800 a192401c05cac418f531fbd36d366ac8 249 SUPERFAMILY SSF53335 217 236 1.66E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14800 a192401c05cac418f531fbd36d366ac8 249 Pfam PF13649 Methyltransferase domain 55 152 2.2E-9 T 09-03-2017 UA74_RS11670 1185fb410c25d5fe7f29316d90b37eda 160 SUPERFAMILY SSF82784 4 150 1.96E-39 T 09-03-2017 IPR003718 OsmC/Ohr family UA74_RS11670 1185fb410c25d5fe7f29316d90b37eda 160 Gene3D G3DSA:3.30.300.20 3 153 4.0E-56 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS11670 1185fb410c25d5fe7f29316d90b37eda 160 Pfam PF02566 OsmC-like protein 51 147 1.1E-11 T 09-03-2017 IPR003718 OsmC/Ohr family UA74_RS13255 a5e251fbdd5eddb44f6905bc2c13429a 138 SMART SM00116 11 59 1.6 T 09-03-2017 IPR000644 CBS domain UA74_RS13255 a5e251fbdd5eddb44f6905bc2c13429a 138 SMART SM00116 77 124 1.1E-4 T 09-03-2017 IPR000644 CBS domain UA74_RS13255 a5e251fbdd5eddb44f6905bc2c13429a 138 SUPERFAMILY SSF54631 3 117 1.39E-26 T 09-03-2017 UA74_RS13255 a5e251fbdd5eddb44f6905bc2c13429a 138 Pfam PF00571 CBS domain 70 116 7.4E-8 T 09-03-2017 IPR000644 CBS domain UA74_RS13255 a5e251fbdd5eddb44f6905bc2c13429a 138 Pfam PF00571 CBS domain 5 57 1.9E-7 T 09-03-2017 IPR000644 CBS domain UA74_RS13255 a5e251fbdd5eddb44f6905bc2c13429a 138 Gene3D G3DSA:3.10.580.10 4 116 1.5E-24 T 09-03-2017 UA74_RS06540 fbcd5f364445eba2eb9918ca2e62a084 394 SUPERFAMILY SSF53383 2 389 2.39E-91 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS06540 fbcd5f364445eba2eb9918ca2e62a084 394 Gene3D G3DSA:3.90.1150.10 251 383 3.6E-34 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS06540 fbcd5f364445eba2eb9918ca2e62a084 394 Pfam PF00266 Aminotransferase class-V 3 379 1.0E-60 T 09-03-2017 IPR000192 Aminotransferase class V domain UA74_RS06540 fbcd5f364445eba2eb9918ca2e62a084 394 PIRSF PIRSF005572 1 393 1.2E-107 T 09-03-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 UA74_RS06540 fbcd5f364445eba2eb9918ca2e62a084 394 Gene3D G3DSA:3.40.640.10 18 250 1.5E-76 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS10425 c561d27ed1b5a943cb2852f8a08ee45c 219 Gene3D G3DSA:3.40.50.300 41 206 3.7E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10425 c561d27ed1b5a943cb2852f8a08ee45c 219 SUPERFAMILY SSF52540 41 206 2.71E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10425 c561d27ed1b5a943cb2852f8a08ee45c 219 Pfam PF13671 AAA domain 42 152 3.2E-9 T 09-03-2017 UA74_RS29170 06df0b90775c7aa77e74fec747825d09 740 Pfam PF01580 FtsK/SpoIIIE family 369 538 2.3E-7 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_RS29170 06df0b90775c7aa77e74fec747825d09 740 SUPERFAMILY SSF52540 306 569 1.33E-10 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS29170 06df0b90775c7aa77e74fec747825d09 740 Gene3D G3DSA:3.40.50.300 323 545 3.4E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11020 d992870af58d104e761df53fb1e41a78 284 Pfam PF05368 NmrA-like family 6 217 8.9E-25 T 09-03-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_RS11020 d992870af58d104e761df53fb1e41a78 284 Gene3D G3DSA:3.40.50.720 1 214 1.3E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11020 d992870af58d104e761df53fb1e41a78 284 SUPERFAMILY SSF51735 5 252 8.45E-59 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29305 cd89874c3677c058f01ac7e3b65f632a 159 SUPERFAMILY SSF52833 50 152 9.72E-13 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS29305 cd89874c3677c058f01ac7e3b65f632a 159 Pfam PF00085 Thioredoxin 67 148 9.9E-7 T 09-03-2017 IPR013766 Thioredoxin domain GO:0045454 UA74_RS29305 cd89874c3677c058f01ac7e3b65f632a 159 Gene3D G3DSA:3.40.30.10 67 149 9.6E-10 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS19880 6278d95ecf11e5841dd41d5dae879429 111 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 36 74 2.5E-6 T 09-03-2017 IPR026496 Putative ATP-grasp target RiPP UA74_RS25130 3b3911e172aca8ad3c52017b89d540c4 311 Pfam PF00294 pfkB family carbohydrate kinase 14 281 5.8E-41 T 09-03-2017 IPR011611 Carbohydrate kinase PfkB UA74_RS25130 3b3911e172aca8ad3c52017b89d540c4 311 SUPERFAMILY SSF53613 10 281 5.14E-49 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS25130 3b3911e172aca8ad3c52017b89d540c4 311 Gene3D G3DSA:3.40.1190.20 30 291 6.6E-41 T 09-03-2017 IPR029056 Ribokinase-like UA74_RS25130 3b3911e172aca8ad3c52017b89d540c4 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 33 57 - T 09-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_RS18545 01065cae100e670bd8f5ac693a1dc096 290 Pfam PF13560 Helix-turn-helix domain 14 73 8.8E-10 T 09-03-2017 UA74_RS18545 01065cae100e670bd8f5ac693a1dc096 290 SMART SM00530 16 71 1.8E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS18545 01065cae100e670bd8f5ac693a1dc096 290 Gene3D G3DSA:1.10.260.40 2 69 3.4E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18545 01065cae100e670bd8f5ac693a1dc096 290 SUPERFAMILY SSF47413 8 69 2.7E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17460 65a723d19d44e75968aefd8cb7645054 284 SUPERFAMILY SSF53474 11 280 3.08E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17460 65a723d19d44e75968aefd8cb7645054 284 Pfam PF12697 Alpha/beta hydrolase family 10 277 2.5E-23 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS17460 65a723d19d44e75968aefd8cb7645054 284 Gene3D G3DSA:3.40.50.1820 10 281 2.7E-44 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18665 4539cba580783e12e15691df84bd92f8 172 SUPERFAMILY SSF50475 20 172 2.01E-46 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS18665 4539cba580783e12e15691df84bd92f8 172 Gene3D G3DSA:2.30.110.10 17 172 2.4E-50 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS18665 4539cba580783e12e15691df84bd92f8 172 SMART SM00903 26 172 3.5E-51 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 UA74_RS18665 4539cba580783e12e15691df84bd92f8 172 Pfam PF01613 Flavin reductase like domain 26 172 5.8E-35 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 UA74_RS20630 4b834415e153999467b373330e684e7f 258 SUPERFAMILY SSF56024 102 239 4.93E-17 T 09-03-2017 UA74_RS20630 4b834415e153999467b373330e684e7f 258 Gene3D G3DSA:3.30.870.10 104 242 1.0E-15 T 09-03-2017 UA74_RS20630 4b834415e153999467b373330e684e7f 258 Pfam PF13091 PLD-like domain 109 235 2.0E-13 T 09-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 UA74_RS12635 68b081a2175ecf20456e9e1354fb9035 153 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 143 3.6E-46 T 09-03-2017 UA74_RS12635 68b081a2175ecf20456e9e1354fb9035 153 Pfam PF01592 NifU-like N terminal domain 6 131 6.8E-27 T 09-03-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 UA74_RS12635 68b081a2175ecf20456e9e1354fb9035 153 Gene3D G3DSA:3.90.1010.10 5 146 4.0E-41 T 09-03-2017 UA74_RS12635 68b081a2175ecf20456e9e1354fb9035 153 SUPERFAMILY SSF82649 2 145 3.66E-42 T 09-03-2017 UA74_RS05475 0081dc61d7c39e33c55732b713d93bc6 207 SUPERFAMILY SSF55961 49 201 1.08E-13 T 09-03-2017 UA74_RS05475 0081dc61d7c39e33c55732b713d93bc6 207 Gene3D G3DSA:3.30.530.20 49 191 3.2E-7 T 09-03-2017 IPR023393 START-like domain UA74_RS05475 0081dc61d7c39e33c55732b713d93bc6 207 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 49 201 6.1E-8 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 Pfam PF02384 N-6 DNA Methylase 158 373 3.4E-31 T 09-03-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 SUPERFAMILY SSF53335 124 439 1.92E-46 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 Gene3D G3DSA:3.40.50.150 150 329 1.8E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 181 195 8.8E-11 T 09-03-2017 UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 279 303 8.8E-11 T 09-03-2017 UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 158 174 8.8E-11 T 09-03-2017 UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 245 257 8.8E-11 T 09-03-2017 UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 248 254 - T 09-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_RS20625 56c0ea2a8f9e7366137b9de62195e861 636 SUPERFAMILY SSF116734 473 613 1.8E-7 T 09-03-2017 UA74_RS05000 e7f925c350a3395bdfe1c274c49c46e0 252 Pfam PF09335 SNARE associated Golgi protein 47 174 1.2E-23 T 09-03-2017 IPR032816 SNARE associated Golgi protein UA74_RS07345 0cbd00aa9224663ac16b59ef3cbe56ed 586 SUPERFAMILY SSF51703 23 580 2.88E-185 T 09-03-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS07345 0cbd00aa9224663ac16b59ef3cbe56ed 586 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 47 585 4.5E-195 T 09-03-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS07345 0cbd00aa9224663ac16b59ef3cbe56ed 586 Gene3D G3DSA:3.20.20.240 48 580 7.3E-209 T 09-03-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS07345 0cbd00aa9224663ac16b59ef3cbe56ed 586 Pfam PF01642 Methylmalonyl-CoA mutase 48 578 1.5E-207 T 09-03-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_RS12915 ac51d84d0c43fd2a2b9738c5d7de01e1 297 Pfam PF12705 PD-(D/E)XK nuclease superfamily 24 270 3.5E-37 T 09-03-2017 UA74_RS12915 ac51d84d0c43fd2a2b9738c5d7de01e1 297 SUPERFAMILY SSF52980 44 205 5.36E-10 T 09-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_RS15940 98e90bafbded1a342ca0931cd71b7cb4 87 Pfam PF09827 CRISPR associated protein Cas2 1 65 1.7E-14 T 09-03-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 UA74_RS15940 98e90bafbded1a342ca0931cd71b7cb4 87 Gene3D G3DSA:3.30.70.240 1 65 6.3E-20 T 09-03-2017 IPR000640 Translation elongation factor EFG, V domain UA74_RS15940 98e90bafbded1a342ca0931cd71b7cb4 87 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 87 13.094 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_RS15940 98e90bafbded1a342ca0931cd71b7cb4 87 SUPERFAMILY SSF143430 1 80 5.49E-20 T 09-03-2017 UA74_RS15940 98e90bafbded1a342ca0931cd71b7cb4 87 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 65 5.3E-8 T 09-03-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_RS16870 9e311750bf54d94d566ef592489df293 497 Pfam PF00135 Carboxylesterase family 3 476 3.9E-83 T 09-03-2017 IPR002018 Carboxylesterase, type B UA74_RS16870 9e311750bf54d94d566ef592489df293 497 Gene3D G3DSA:3.40.50.1820 4 490 1.8E-111 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16870 9e311750bf54d94d566ef592489df293 497 SUPERFAMILY SSF53474 4 489 7.7E-98 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16870 9e311750bf54d94d566ef592489df293 497 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 170 185 - T 09-03-2017 IPR019826 Carboxylesterase type B, active site UA74_RS25165 8f9ff30709bb0aa61e906156ea56ed30 190 SUPERFAMILY SSF52540 13 189 9.16E-40 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25165 8f9ff30709bb0aa61e906156ea56ed30 190 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 13 189 1.2E-51 T 09-03-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS25165 8f9ff30709bb0aa61e906156ea56ed30 190 Gene3D G3DSA:3.40.50.300 13 189 9.6E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS25165 8f9ff30709bb0aa61e906156ea56ed30 190 PIRSF PIRSF006135 11 190 2.4E-48 T 09-03-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 UA74_RS05695 9983a03769b49a4d8900d960f2198d2c 192 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 17 184 5.9E-20 T 09-03-2017 IPR009936 Protein of unknown function DUF1468 UA74_RS01755 4b008c8ffa7fd7ea227f4cba4eb508a3 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 314 9.1E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01755 4b008c8ffa7fd7ea227f4cba4eb508a3 324 Gene3D G3DSA:1.10.3720.10 96 320 8.0E-62 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01755 4b008c8ffa7fd7ea227f4cba4eb508a3 324 SUPERFAMILY SSF161098 81 310 7.85E-57 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS28290 64166e3341bd92b6e044096c8e71b587 281 SUPERFAMILY SSF54593 19 128 2.18E-7 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS28290 64166e3341bd92b6e044096c8e71b587 281 Gene3D G3DSA:3.10.180.10 18 132 9.0E-19 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS28290 64166e3341bd92b6e044096c8e71b587 281 Gene3D G3DSA:3.10.180.10 146 265 4.8E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS28290 64166e3341bd92b6e044096c8e71b587 281 SUPERFAMILY SSF54593 146 263 3.3E-14 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS20260 92d00555624c91615c7317b90d32b787 90 Pfam PF03668 P-loop ATPase protein family 35 82 2.6E-6 T 09-03-2017 IPR005337 RapZ-like family GO:0005524 UA74_RS03390 3db180a6fd73b0ba0cae1ae36613cb37 211 SUPERFAMILY SSF51735 1 202 1.25E-38 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03390 3db180a6fd73b0ba0cae1ae36613cb37 211 Pfam PF13460 NAD(P)H-binding 7 199 4.5E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS03390 3db180a6fd73b0ba0cae1ae36613cb37 211 Gene3D G3DSA:3.40.50.720 1 201 1.0E-46 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS06985 2a4790e3ca408ce965e502cc99236eb5 334 Pfam PF05235 CHAD domain 28 283 2.0E-45 T 09-03-2017 IPR007899 CHAD domain UA74_RS06985 2a4790e3ca408ce965e502cc99236eb5 334 SMART SM00880 28 315 2.8E-54 T 09-03-2017 IPR007899 CHAD domain UA74_RS16655 32ea4c36b6060918216147ffd5611f6d 296 SUPERFAMILY SSF161098 94 272 1.57E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS16655 32ea4c36b6060918216147ffd5611f6d 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 286 3.1E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22325 e740491b7d3c007dc76f828ad6eb41c9 324 Gene3D G3DSA:3.40.50.1980 175 318 4.3E-17 T 09-03-2017 UA74_RS22325 e740491b7d3c007dc76f828ad6eb41c9 324 Pfam PF01497 Periplasmic binding protein 85 299 3.4E-19 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS22325 e740491b7d3c007dc76f828ad6eb41c9 324 Gene3D G3DSA:3.40.50.1980 91 174 4.7E-7 T 09-03-2017 UA74_RS22325 e740491b7d3c007dc76f828ad6eb41c9 324 SUPERFAMILY SSF53807 24 304 4.32E-35 T 09-03-2017 UA74_RS04570 e4cdfc91106e0e544003b4667f2de4eb 489 SUPERFAMILY SSF140459 29 183 4.97E-7 T 09-03-2017 UA74_RS25235 735ea5d3f473938d1f50e17a116e3865 309 SUPERFAMILY SSF51735 13 256 1.11E-53 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS25235 735ea5d3f473938d1f50e17a116e3865 309 Pfam PF00106 short chain dehydrogenase 16 220 3.0E-31 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25235 735ea5d3f473938d1f50e17a116e3865 309 Gene3D G3DSA:3.40.50.720 7 255 1.3E-56 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS25235 735ea5d3f473938d1f50e17a116e3865 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.5E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25235 735ea5d3f473938d1f50e17a116e3865 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.5E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25235 735ea5d3f473938d1f50e17a116e3865 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.5E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS25235 735ea5d3f473938d1f50e17a116e3865 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 1.5E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21095 30d2bba6b645bbcc53443195bad3e954 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.4E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21095 30d2bba6b645bbcc53443195bad3e954 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.4E-6 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS21095 30d2bba6b645bbcc53443195bad3e954 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS21095 30d2bba6b645bbcc53443195bad3e954 255 SUPERFAMILY SSF51735 7 238 3.85E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21095 30d2bba6b645bbcc53443195bad3e954 255 Gene3D G3DSA:3.40.50.720 4 234 3.3E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21095 30d2bba6b645bbcc53443195bad3e954 255 Pfam PF00106 short chain dehydrogenase 14 189 2.0E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS22935 c93216c6a39c43a3717afd3e897f4a78 203 Pfam PF07336 Putative stress-induced transcription regulator 6 149 1.9E-14 T 09-03-2017 IPR010852 Putative stress-induced transcription regulator UA74_RS22935 c93216c6a39c43a3717afd3e897f4a78 203 SUPERFAMILY SSF160904 3 192 4.58E-35 T 09-03-2017 UA74_RS22935 c93216c6a39c43a3717afd3e897f4a78 203 Gene3D G3DSA:1.10.3300.10 5 194 4.7E-35 T 09-03-2017 IPR023286 ABATE domain UA74_RS22935 c93216c6a39c43a3717afd3e897f4a78 203 Pfam PF11706 CGNR zinc finger 153 193 1.5E-10 T 09-03-2017 IPR021005 Zinc finger, CGNR UA74_RS13190 0ac2b78af90156aae23ca76bc05224f1 413 Gene3D G3DSA:3.40.50.2000 4 248 3.6E-6 T 09-03-2017 UA74_RS13190 0ac2b78af90156aae23ca76bc05224f1 413 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 246 384 2.8E-9 T 09-03-2017 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 UA74_RS13190 0ac2b78af90156aae23ca76bc05224f1 413 SUPERFAMILY SSF53756 3 410 2.51E-62 T 09-03-2017 UA74_RS13190 0ac2b78af90156aae23ca76bc05224f1 413 Gene3D G3DSA:3.40.50.2000 249 390 8.1E-21 T 09-03-2017 UA74_RS03355 2f64461db394a998b21ca577ef3727f3 187 SUPERFAMILY SSF160904 15 186 1.01E-38 T 09-03-2017 UA74_RS03355 2f64461db394a998b21ca577ef3727f3 187 Pfam PF11706 CGNR zinc finger 145 186 2.9E-19 T 09-03-2017 IPR021005 Zinc finger, CGNR UA74_RS03355 2f64461db394a998b21ca577ef3727f3 187 Pfam PF07336 Putative stress-induced transcription regulator 20 141 1.5E-17 T 09-03-2017 IPR010852 Putative stress-induced transcription regulator UA74_RS03355 2f64461db394a998b21ca577ef3727f3 187 Gene3D G3DSA:1.10.3300.10 15 186 3.3E-41 T 09-03-2017 IPR023286 ABATE domain UA74_RS18790 227f12fe83046884fda68d1bb9c09a59 407 Gene3D G3DSA:1.10.10.10 328 406 1.5E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS18790 227f12fe83046884fda68d1bb9c09a59 407 SUPERFAMILY SSF46785 328 406 4.55E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 PIRSF PIRSF037434 5 414 5.1E-69 T 09-03-2017 IPR017205 Signal transduction histidine kinase, ChrS UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 Pfam PF07730 Histidine kinase 216 282 4.6E-14 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 SMART SM00387 320 411 2.5E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 Gene3D G3DSA:3.30.565.10 290 371 3.4E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 Gene3D G3DSA:3.30.565.10 372 408 4.3E-7 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 SUPERFAMILY SSF55874 287 408 1.7E-22 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 408 5.2E-9 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 408 1.7E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 1.7E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS05310 3147a3adbf71b355bda9ca2a38be76b7 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 1.7E-8 T 09-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_RS27105 f8c1ada59e148c1b2630ea00ebee4cdd 369 SUPERFAMILY SSF53850 64 361 3.2E-50 T 09-03-2017 UA74_RS27105 f8c1ada59e148c1b2630ea00ebee4cdd 369 Gene3D G3DSA:3.40.190.10 296 348 9.1E-31 T 09-03-2017 UA74_RS27105 f8c1ada59e148c1b2630ea00ebee4cdd 369 Gene3D G3DSA:3.40.190.10 1 160 9.1E-31 T 09-03-2017 UA74_RS27105 f8c1ada59e148c1b2630ea00ebee4cdd 369 Pfam PF13343 Bacterial extracellular solute-binding protein 120 333 7.9E-23 T 09-03-2017 UA74_RS27105 f8c1ada59e148c1b2630ea00ebee4cdd 369 Gene3D G3DSA:3.40.190.10 166 295 7.0E-28 T 09-03-2017 UA74_RS25910 c119ccd8e4c6ade1e89268009545c200 136 Gene3D G3DSA:3.30.1330.40 1 136 1.6E-37 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS25910 c119ccd8e4c6ade1e89268009545c200 136 SUPERFAMILY SSF55298 2 135 2.04E-29 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS25910 c119ccd8e4c6ade1e89268009545c200 136 Pfam PF01042 Endoribonuclease L-PSP 17 134 1.0E-21 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family UA74_RS02140 e5d4b964ac6a5328cbbeb65b5149ec17 307 SUPERFAMILY SSF51679 14 283 1.18E-41 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS02140 e5d4b964ac6a5328cbbeb65b5149ec17 307 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 12 305 4.4E-98 T 09-03-2017 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted UA74_RS02140 e5d4b964ac6a5328cbbeb65b5149ec17 307 Pfam PF00296 Luciferase-like monooxygenase 14 280 2.0E-24 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS02140 e5d4b964ac6a5328cbbeb65b5149ec17 307 Gene3D G3DSA:3.20.20.30 14 304 4.1E-31 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS07305 c7d5a38784f419aa473a6cb77212e7eb 156 SUPERFAMILY SSF54593 9 147 2.75E-31 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS07305 c7d5a38784f419aa473a6cb77212e7eb 156 Gene3D G3DSA:3.10.180.10 9 143 1.8E-35 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS07305 c7d5a38784f419aa473a6cb77212e7eb 156 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 12 143 1.7E-35 T 09-03-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 UA74_RS07305 c7d5a38784f419aa473a6cb77212e7eb 156 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 122 2.1E-17 T 09-03-2017 UA74_RS16725 1efdc2f95aefe968cd18fabc744db68b 350 Pfam PF01032 FecCD transport family 25 343 6.0E-90 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS16725 1efdc2f95aefe968cd18fabc744db68b 350 Gene3D G3DSA:1.10.3470.10 12 347 1.1E-103 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS16725 1efdc2f95aefe968cd18fabc744db68b 350 SUPERFAMILY SSF81345 10 344 1.96E-79 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS29215 c1bebe024800aead0121277e692d87e3 415 Gene3D G3DSA:1.20.1250.20 22 200 3.5E-16 T 09-03-2017 UA74_RS29215 c1bebe024800aead0121277e692d87e3 415 Gene3D G3DSA:1.20.1250.20 229 403 1.5E-10 T 09-03-2017 UA74_RS29215 c1bebe024800aead0121277e692d87e3 415 Pfam PF05977 Transmembrane secretion effector 11 396 7.2E-39 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS29215 c1bebe024800aead0121277e692d87e3 415 SUPERFAMILY SSF103473 17 405 4.19E-38 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS14435 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 368 397 1100.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS14435 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 158 180 1000.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS14435 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 211 233 2600.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS14435 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 316 338 220.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS14435 d24863e3cf8741acbdf0bdbecd7d3a0d 408 Pfam PF13229 Right handed beta helix region 153 263 9.8E-5 T 09-03-2017 UA74_RS14435 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SUPERFAMILY SSF51126 89 408 7.6E-14 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS14435 d24863e3cf8741acbdf0bdbecd7d3a0d 408 Gene3D G3DSA:2.160.20.10 89 398 1.3E-4 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS21005 dd7c55d6915b735b048bb787a4a6768d 265 SUPERFAMILY SSF56059 70 258 8.97E-15 T 09-03-2017 UA74_RS09790 30528fbffa87350c4b5e077c58afdf6c 205 Hamap MF_01197 Cell division protein SepF [sepF]. 1 198 21.761 T 09-03-2017 IPR023052 Cell division protein SepF GO:0090529 UA74_RS09790 30528fbffa87350c4b5e077c58afdf6c 205 Pfam PF04472 Protein of unknown function (DUF552) 119 190 2.8E-24 T 09-03-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 Pfam PF03466 LysR substrate binding domain 88 281 1.9E-41 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 Gene3D G3DSA:3.40.190.10 90 175 3.5E-17 T 09-03-2017 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.6E-20 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.6E-7 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.6E-7 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.6E-7 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 Gene3D G3DSA:3.40.190.10 176 260 6.0E-21 T 09-03-2017 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 SUPERFAMILY SSF53850 88 281 6.04E-38 T 09-03-2017 UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 Gene3D G3DSA:1.10.10.10 1 82 2.8E-26 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS03330 9a70faf47f362d798255338a53ad04f7 306 SUPERFAMILY SSF46785 1 82 9.25E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS26075 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 8.7E-22 T 09-03-2017 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 8.7E-22 T 09-03-2017 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 8.7E-22 T 09-03-2017 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 8.7E-22 T 09-03-2017 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 SUPERFAMILY SSF51905 15 184 4.08E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 SUPERFAMILY SSF51905 276 366 4.08E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 Pfam PF01494 FAD binding domain 14 322 1.0E-53 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 Gene3D G3DSA:3.50.50.60 287 324 1.5E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS26075 a25a961146a598be6afc90abe910b493 429 Gene3D G3DSA:3.50.50.60 15 187 1.5E-42 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09760 0ca5af60118727b39ac8498b21f4f505 249 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 243 41.312 T 09-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF UA74_RS09760 0ca5af60118727b39ac8498b21f4f505 249 SUPERFAMILY SSF88713 1 248 1.56E-93 T 09-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UA74_RS09760 0ca5af60118727b39ac8498b21f4f505 249 Pfam PF03746 LamB/YcsF family 1 238 7.9E-98 T 09-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF UA74_RS16035 ba7ecd4832f796ad96910cc70d078852 589 SUPERFAMILY SSF56349 60 367 6.73E-46 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS16035 ba7ecd4832f796ad96910cc70d078852 589 Gene3D G3DSA:1.10.443.10 170 366 5.2E-27 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS16035 ba7ecd4832f796ad96910cc70d078852 589 Gene3D G3DSA:1.10.150.130 60 150 2.1E-14 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS16035 ba7ecd4832f796ad96910cc70d078852 589 Pfam PF00589 Phage integrase family 171 360 8.9E-15 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS10140 4c4210128a644e2aee46bc098f4c84e5 345 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 276 15.64 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UA74_RS10140 4c4210128a644e2aee46bc098f4c84e5 345 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 267 4.9E-42 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UA74_RS10140 4c4210128a644e2aee46bc098f4c84e5 345 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 270 1.0E-64 T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UA74_RS10140 4c4210128a644e2aee46bc098f4c84e5 345 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 09-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UA74_RS28680 cc2ed6b77e2d7377e19ec3489fc638cd 75 Pfam PF04024 PspC domain 15 73 7.4E-19 T 09-03-2017 IPR007168 Phage shock protein, PspC, N-terminal UA74_RS18865 0dbafcfaecfe904c1ff66582093c73ca 430 Gene3D G3DSA:3.40.190.10 167 353 5.2E-43 T 09-03-2017 UA74_RS18865 0dbafcfaecfe904c1ff66582093c73ca 430 SUPERFAMILY SSF53850 26 423 1.72E-58 T 09-03-2017 UA74_RS18865 0dbafcfaecfe904c1ff66582093c73ca 430 Pfam PF13416 Bacterial extracellular solute-binding protein 58 355 3.1E-26 T 09-03-2017 UA74_RS18865 0dbafcfaecfe904c1ff66582093c73ca 430 Gene3D G3DSA:3.40.190.10 39 166 1.5E-13 T 09-03-2017 UA74_RS13000 3e24b6a7f86e78fc1a165918e46e4c27 498 Gene3D G3DSA:1.20.144.10 10 179 2.6E-37 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS13000 3e24b6a7f86e78fc1a165918e46e4c27 498 SUPERFAMILY SSF48317 18 179 1.31E-39 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS13000 3e24b6a7f86e78fc1a165918e46e4c27 498 SUPERFAMILY SSF111331 204 491 3.05E-42 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain UA74_RS13000 3e24b6a7f86e78fc1a165918e46e4c27 498 SMART SM00014 67 176 3.9E-20 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS13000 3e24b6a7f86e78fc1a165918e46e4c27 498 SMART SM00046 203 331 2.9E-8 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_RS13000 3e24b6a7f86e78fc1a165918e46e4c27 498 Pfam PF00781 Diacylglycerol kinase catalytic domain 204 321 1.7E-12 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_RS13000 3e24b6a7f86e78fc1a165918e46e4c27 498 Pfam PF01569 PAP2 superfamily 69 180 4.7E-19 T 09-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_RS23730 9d7d20b89c2d4430eb96cacb6be25768 242 SUPERFAMILY SSF53597 17 232 2.8E-44 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS23730 9d7d20b89c2d4430eb96cacb6be25768 242 Gene3D G3DSA:3.40.430.10 8 239 7.0E-66 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS23730 9d7d20b89c2d4430eb96cacb6be25768 242 Pfam PF01872 RibD C-terminal domain 19 208 5.6E-33 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS11835 1d0c2e8c5fe2e1ccb8c8575853ef0e4c 96 Pfam PF04972 BON domain 22 84 1.9E-8 T 09-03-2017 IPR007055 BON domain UA74_RS03480 f9dfc425a9c321d1bd2892932450cbb3 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 1.5E-19 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS00810 06833bfd330786d1b95debd18f0f03be 57 Pfam PF14013 MT0933-like antitoxin protein 9 53 7.0E-9 T 09-03-2017 IPR028037 Antitoxin Rv0909/MT0933 UA74_RS27380 0faf159b92ff326083ecd0ef7fc876d8 88 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 81 1.2E-6 T 09-03-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 UA74_RS01670 c38eb18bf6559ddd98920616a7a506d1 477 PIRSF PIRSF016636 1 477 8.7E-148 T 09-03-2017 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB UA74_RS01670 c38eb18bf6559ddd98920616a7a506d1 477 PIRSF PIRSF500217 1 477 7.0E-150 T 09-03-2017 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 UA74_RS01670 c38eb18bf6559ddd98920616a7a506d1 477 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 152 356 8.1E-33 T 09-03-2017 IPR004299 Membrane bound O-acyl transferase, MBOAT UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 SUPERFAMILY SSF51735 2 265 4.12E-63 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 264 1.1E-47 T 09-03-2017 UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 4.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 4.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 4.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 4.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 4.9E-30 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 Gene3D G3DSA:3.40.50.720 3 264 3.3E-71 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 9.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 9.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 9.5E-8 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05240 48fe4ef25d3a16044c63fc609af6d7b5 269 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 266 1.4E-104 T 09-03-2017 IPR023985 Mycofactocin-dependent oxidoreductase UA74_RS10755 3a526e057925798914cd68292ec8260a 172 SUPERFAMILY SSF159234 7 170 2.75E-26 T 09-03-2017 UA74_RS10755 3a526e057925798914cd68292ec8260a 172 Gene3D G3DSA:2.40.380.10 5 165 2.0E-30 T 09-03-2017 IPR007295 Domain of unknown function DUF402 UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 4.3E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.3E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 4.3E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.3E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 4.3E-34 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 SUPERFAMILY SSF51735 8 255 2.69E-64 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 Gene3D G3DSA:3.40.50.720 5 255 2.0E-66 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS05565 d6deb194d5bf8385306f3c4659f921f8 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 8.8E-49 T 09-03-2017 UA74_RS16915 4e059de06f4566b520638f8d6a7b497d 470 Pfam PF07690 Major Facilitator Superfamily 2 394 8.0E-46 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS16915 4e059de06f4566b520638f8d6a7b497d 470 Gene3D G3DSA:1.20.1250.20 248 457 4.1E-19 T 09-03-2017 UA74_RS16915 4e059de06f4566b520638f8d6a7b497d 470 Gene3D G3DSA:1.20.1250.20 1 180 1.4E-26 T 09-03-2017 UA74_RS16915 4e059de06f4566b520638f8d6a7b497d 470 SUPERFAMILY SSF103473 2 180 1.07E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS16915 4e059de06f4566b520638f8d6a7b497d 470 SUPERFAMILY SSF103473 233 455 1.07E-56 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19295 1ab458b71b7320e2dcb3895f1b809962 466 Pfam PF02386 Cation transport protein 45 444 3.6E-54 T 09-03-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 UA74_RS12695 e47da0b786af8b19ee195a11f2791137 199 Gene3D G3DSA:3.40.50.150 159 181 8.6E-6 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12695 e47da0b786af8b19ee195a11f2791137 199 Gene3D G3DSA:3.40.50.150 54 115 8.6E-6 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12695 e47da0b786af8b19ee195a11f2791137 199 SUPERFAMILY SSF53335 59 183 4.61E-7 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 SUPERFAMILY SSF51905 2 271 2.46E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 SUPERFAMILY SSF51905 342 379 2.46E-22 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 349 356 1.3E-5 T 09-03-2017 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.3E-5 T 09-03-2017 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 63 2.0E-8 T 09-03-2017 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 Gene3D G3DSA:3.50.50.60 4 52 5.8E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 Gene3D G3DSA:3.50.50.60 295 296 5.8E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 Gene3D G3DSA:3.50.50.60 171 250 5.8E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS04985 074a3449eb04746c97f7b8b423d75025 388 Gene3D G3DSA:3.50.50.60 347 381 5.8E-20 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 4.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 4.9E-12 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 SUPERFAMILY SSF51735 5 249 5.31E-42 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 Pfam PF00106 short chain dehydrogenase 6 202 3.3E-25 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07580 34ca5a29df3e3ad2e6eeacf7e774def3 293 Gene3D G3DSA:3.40.50.720 4 249 4.6E-44 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS27610 095dad3aaf3d522cf6725241604ea3b8 111 Gene3D G3DSA:1.10.10.10 6 95 5.7E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27610 095dad3aaf3d522cf6725241604ea3b8 111 Pfam PF13601 Winged helix DNA-binding domain 17 94 5.4E-15 T 09-03-2017 IPR027395 Winged helix DNA-binding domain UA74_RS27610 095dad3aaf3d522cf6725241604ea3b8 111 SUPERFAMILY SSF46785 12 95 4.77E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 476 798 6.0E-143 T 09-03-2017 IPR032380 Polynucleotide kinase-phosphatase, ligase domain UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 SUPERFAMILY SSF56300 180 406 2.66E-40 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 3 861 0.0 T 09-03-2017 IPR024028 Polynucleotide kinase-phosphatase, bacterial UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF13671 AAA domain 11 140 8.4E-20 T 09-03-2017 UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 802 861 1.4E-31 T 09-03-2017 IPR032390 Polynucleotide kinase-phosphatase, C-terminal UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 SUPERFAMILY SSF56091 524 623 8.63E-11 T 09-03-2017 UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 SUPERFAMILY SSF56091 656 772 8.63E-11 T 09-03-2017 UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF00149 Calcineurin-like phosphoesterase 182 388 2.2E-10 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Gene3D G3DSA:3.40.50.300 11 137 1.4E-21 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 SUPERFAMILY SSF52540 11 145 3.24E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Gene3D G3DSA:3.60.21.10 179 423 3.6E-51 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS13015 cd11987c14af532365ed11dfe1a3bea0 329 PIRSF PIRSF016838 1 320 6.1E-119 T 09-03-2017 IPR028349 Protein PafC UA74_RS13015 cd11987c14af532365ed11dfe1a3bea0 329 Pfam PF13280 WYL domain 149 312 1.1E-33 T 09-03-2017 IPR026881 WYL domain UA74_RS19245 951ff6a10f652e6bf5e52f1b4bba6490 125 Pfam PF03334 Na+/H+ antiporter subunit 13 91 1.9E-19 T 09-03-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 UA74_RS19245 951ff6a10f652e6bf5e52f1b4bba6490 125 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 104 1.8E-18 T 09-03-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 UA74_RS08395 dbd2d7c1cb873d80aa777a167bad0f84 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 3.0E-23 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08395 dbd2d7c1cb873d80aa777a167bad0f84 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.595 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08395 dbd2d7c1cb873d80aa777a167bad0f84 86 Gene3D G3DSA:1.20.58.110 3 86 4.7E-29 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08395 dbd2d7c1cb873d80aa777a167bad0f84 86 Pfam PF01649 Ribosomal protein S20 2 84 3.1E-27 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08395 dbd2d7c1cb873d80aa777a167bad0f84 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 83 2.9E-22 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS08395 dbd2d7c1cb873d80aa777a167bad0f84 86 SUPERFAMILY SSF46992 3 86 1.05E-27 T 09-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21085 c1b8cded4e7207ca1aef9b6197dbe74e 457 Gene3D G3DSA:3.30.420.40 10 142 5.7E-11 T 09-03-2017 UA74_RS21085 c1b8cded4e7207ca1aef9b6197dbe74e 457 SUPERFAMILY SSF53067 11 224 7.98E-19 T 09-03-2017 UA74_RS21085 c1b8cded4e7207ca1aef9b6197dbe74e 457 SUPERFAMILY SSF53067 334 439 7.98E-19 T 09-03-2017 UA74_RS21085 c1b8cded4e7207ca1aef9b6197dbe74e 457 Gene3D G3DSA:3.30.420.40 143 223 1.2E-8 T 09-03-2017 UA74_RS21085 c1b8cded4e7207ca1aef9b6197dbe74e 457 Gene3D G3DSA:3.30.420.40 323 402 1.2E-8 T 09-03-2017 UA74_RS21085 c1b8cded4e7207ca1aef9b6197dbe74e 457 Pfam PF00480 ROK family 13 211 8.4E-9 T 09-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS26855 450d3a5e2fa3521b58f4495e2ae15677 219 SUPERFAMILY SSF141571 52 208 9.94E-17 T 09-03-2017 UA74_RS04960 0aa82937383322abc407459327ad5bb7 229 SUPERFAMILY SSF52540 1 220 1.87E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04960 0aa82937383322abc407459327ad5bb7 229 Pfam PF00005 ABC transporter 19 166 2.9E-34 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS04960 0aa82937383322abc407459327ad5bb7 229 Gene3D G3DSA:3.40.50.300 1 219 4.9E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04960 0aa82937383322abc407459327ad5bb7 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS04960 0aa82937383322abc407459327ad5bb7 229 SMART SM00382 28 215 3.9E-15 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS04960 0aa82937383322abc407459327ad5bb7 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.3E-85 T 09-03-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 Pfam PF00905 Penicillin binding protein transpeptidase domain 374 647 6.5E-23 T 09-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 Gene3D G3DSA:1.10.3810.10 69 270 3.1E-63 T 09-03-2017 UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 Gene3D G3DSA:3.40.710.10 307 703 2.3E-82 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 Pfam PF00912 Transglycosylase 69 257 3.4E-57 T 09-03-2017 IPR001264 Glycosyl transferase, family 51 UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 SUPERFAMILY SSF56601 534 706 2.91E-77 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 SUPERFAMILY SSF56601 239 261 2.91E-77 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 SUPERFAMILY SSF56601 306 504 2.91E-77 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS21330 685717fe897cf8729ee902d11a6d34f5 709 SUPERFAMILY SSF53955 58 274 1.15E-60 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS01095 9b6c43f8bb66ea0583460113ef8194bb 186 Gene3D G3DSA:3.40.50.360 3 183 3.6E-45 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS01095 9b6c43f8bb66ea0583460113ef8194bb 186 Pfam PF03358 NADPH-dependent FMN reductase 4 144 5.5E-23 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS01095 9b6c43f8bb66ea0583460113ef8194bb 186 SUPERFAMILY SSF52218 4 177 2.35E-33 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS25265 2e5b1ad22ccadfdd637ebeeaf48785c2 311 Gene3D G3DSA:1.20.120.350 13 111 1.6E-13 T 09-03-2017 IPR027359 Voltage-dependent channel, four helix bundle domain UA74_RS25265 2e5b1ad22ccadfdd637ebeeaf48785c2 311 Pfam PF00520 Ion transport protein 14 225 4.0E-46 T 09-03-2017 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 UA74_RS25265 2e5b1ad22ccadfdd637ebeeaf48785c2 311 SUPERFAMILY SSF81324 13 223 3.14E-35 T 09-03-2017 UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 Gene3D G3DSA:3.90.120.10 356 418 2.3E-8 T 09-03-2017 UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 106 118 - T 09-03-2017 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 220 233 1.2E-12 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 19 35 1.2E-12 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 144 158 1.2E-12 T 09-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 Pfam PF00145 C-5 cytosine-specific DNA methylase 207 429 1.4E-20 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 Pfam PF00145 C-5 cytosine-specific DNA methylase 20 173 1.3E-25 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 Gene3D G3DSA:3.40.50.150 20 248 2.9E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 Gene3D G3DSA:3.40.50.150 291 309 2.9E-48 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 SUPERFAMILY SSF53335 203 248 1.28E-68 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 SUPERFAMILY SSF53335 20 172 1.28E-68 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS24935 bc387b796647e7ca3fb3ea7fd9b41de8 445 SUPERFAMILY SSF53335 296 434 1.28E-68 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28935 5742de6509c5602ee9eeb14dfa3571b2 449 SUPERFAMILY SSF53383 11 417 3.86E-77 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS28935 5742de6509c5602ee9eeb14dfa3571b2 449 Gene3D G3DSA:3.90.1150.10 11 80 5.9E-18 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS28935 5742de6509c5602ee9eeb14dfa3571b2 449 Gene3D G3DSA:3.90.1150.10 323 417 5.9E-18 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS28935 5742de6509c5602ee9eeb14dfa3571b2 449 Pfam PF00202 Aminotransferase class-III 45 390 6.0E-36 T 09-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_RS28935 5742de6509c5602ee9eeb14dfa3571b2 449 Gene3D G3DSA:3.40.640.10 81 317 6.9E-46 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS28360 d5d1e0521c69d6d460da380c99dd23cc 269 Gene3D G3DSA:3.40.630.30 127 246 3.5E-12 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS28360 d5d1e0521c69d6d460da380c99dd23cc 269 SUPERFAMILY SSF55729 128 243 9.17E-13 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS28360 d5d1e0521c69d6d460da380c99dd23cc 269 Pfam PF00583 Acetyltransferase (GNAT) family 179 240 2.9E-9 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS09650 51ebef95ab602bb3846bf37695952831 137 Pfam PF11239 Protein of unknown function (DUF3040) 1 85 8.9E-30 T 09-03-2017 IPR021401 Protein of unknown function DUF3040 UA74_RS04485 311ebee46d4932b6682b91125157b58b 209 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 7 199 2.1E-47 T 09-03-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 UA74_RS04485 311ebee46d4932b6682b91125157b58b 209 Pfam PF03358 NADPH-dependent FMN reductase 7 134 1.2E-17 T 09-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_RS04485 311ebee46d4932b6682b91125157b58b 209 Gene3D G3DSA:3.40.50.360 5 205 9.0E-65 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS04485 311ebee46d4932b6682b91125157b58b 209 SUPERFAMILY SSF52218 8 200 5.5E-49 T 09-03-2017 IPR029039 Flavoprotein-like domain UA74_RS26185 50d9f918d84714a9a112f6ce60b0e569 184 Pfam PF07681 DoxX 29 110 5.7E-16 T 09-03-2017 IPR032808 DoxX family UA74_RS01800 56391fe0739d91a4dc17b7dd3dc966f0 328 SUPERFAMILY SSF51430 13 326 4.58E-88 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS01800 56391fe0739d91a4dc17b7dd3dc966f0 328 Gene3D G3DSA:3.20.20.100 13 326 5.5E-86 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS01800 56391fe0739d91a4dc17b7dd3dc966f0 328 Pfam PF00248 Aldo/keto reductase family 28 326 7.9E-64 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS07745 9c0994ff65116826ac754ce13ba77931 360 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 95 6.0E-9 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS07745 9c0994ff65116826ac754ce13ba77931 360 SUPERFAMILY SSF46785 29 134 1.73E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07745 9c0994ff65116826ac754ce13ba77931 360 SUPERFAMILY SSF53850 142 263 6.64E-5 T 09-03-2017 UA74_RS07745 9c0994ff65116826ac754ce13ba77931 360 Gene3D G3DSA:1.10.10.10 29 115 9.4E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21140 112778825435ee8e8c45832e6822edf1 335 SUPERFAMILY SSF161098 87 320 8.76E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21140 112778825435ee8e8c45832e6822edf1 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 328 3.5E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21140 112778825435ee8e8c45832e6822edf1 335 Gene3D G3DSA:1.10.3720.10 93 327 6.3E-60 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21000 53e857a2488b2d9b4ba6fe96e9878dac 359 SUPERFAMILY SSF53335 7 203 4.27E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS21000 53e857a2488b2d9b4ba6fe96e9878dac 359 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 203 2.3E-29 T 09-03-2017 UA74_RS21000 53e857a2488b2d9b4ba6fe96e9878dac 359 Gene3D G3DSA:3.40.50.150 13 205 6.3E-49 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28685 815797c1a6c09fba30246883252662f8 187 Gene3D G3DSA:3.20.20.80 30 98 4.2E-9 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS28685 815797c1a6c09fba30246883252662f8 187 SUPERFAMILY SSF51445 21 99 1.98E-6 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS28685 815797c1a6c09fba30246883252662f8 187 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 14 98 2.6E-6 T 09-03-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 73 375 2.2E-66 T 09-03-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 SMART SM00939 390 606 5.0E-40 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 402 603 3.8E-39 T 09-03-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 Gene3D G3DSA:3.40.50.1820 322 425 5.8E-86 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 Gene3D G3DSA:3.40.50.1820 58 254 5.8E-86 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 SUPERFAMILY SSF49785 467 611 1.23E-32 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 SUPERFAMILY SSF53474 43 425 2.26E-76 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 Gene3D G3DSA:2.60.120.260 426 609 2.6E-48 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 59 69 1.0E-17 T 09-03-2017 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 94 110 1.0E-17 T 09-03-2017 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 43 55 1.0E-17 T 09-03-2017 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 254 270 1.0E-17 T 09-03-2017 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 77 86 1.0E-17 T 09-03-2017 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_RS08805 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 574 589 1.0E-17 T 09-03-2017 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_RS12615 33c29d5039dad0ba340e7b1a05d4f0ee 374 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 91 361 2.9E-74 T 09-03-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 UA74_RS12615 33c29d5039dad0ba340e7b1a05d4f0ee 374 SUPERFAMILY SSF101960 17 369 9.68E-88 T 09-03-2017 UA74_RS12615 33c29d5039dad0ba340e7b1a05d4f0ee 374 Pfam PF01458 Uncharacterized protein family (UPF0051) 124 344 1.8E-70 T 09-03-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 UA74_RS22595 d7072d2bfe00f700d2d8b0ebe62aa096 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 23 91 1.0E-12 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS22595 d7072d2bfe00f700d2d8b0ebe62aa096 144 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 13 138 1.3E-24 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS22595 d7072d2bfe00f700d2d8b0ebe62aa096 144 Gene3D G3DSA:2.30.110.10 7 140 7.9E-25 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS22595 d7072d2bfe00f700d2d8b0ebe62aa096 144 SUPERFAMILY SSF50475 6 140 9.54E-23 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS18995 5a2ae20ae79fac278a04e5efe25c14a3 122 Gene3D G3DSA:3.10.450.50 4 120 1.2E-15 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS18995 5a2ae20ae79fac278a04e5efe25c14a3 122 SUPERFAMILY SSF54427 1 117 2.1E-34 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS18995 5a2ae20ae79fac278a04e5efe25c14a3 122 Pfam PF12680 SnoaL-like domain 9 110 1.2E-12 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS08920 bae05559063c174c65a5d05ac43dff03 258 Pfam PF02517 CAAX protease self-immunity 155 243 2.5E-15 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 UA74_RS02555 0ca3489ee747005706a9b98deeb64b47 473 SUPERFAMILY SSF56762 80 473 1.57E-115 T 09-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02555 0ca3489ee747005706a9b98deeb64b47 473 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 70 473 1.5E-163 T 09-03-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02555 0ca3489ee747005706a9b98deeb64b47 473 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 66 473 46.594 T 09-03-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02555 0ca3489ee747005706a9b98deeb64b47 473 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 185 473 1.1E-105 T 09-03-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02555 0ca3489ee747005706a9b98deeb64b47 473 Gene3D G3DSA:1.10.645.10 401 466 8.8E-61 T 09-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02555 0ca3489ee747005706a9b98deeb64b47 473 Gene3D G3DSA:1.10.645.10 65 357 8.8E-61 T 09-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02555 0ca3489ee747005706a9b98deeb64b47 473 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 107 118 - T 09-03-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02710 bf2f6c74c11941273399228ffad276b6 134 Pfam PF01042 Endoribonuclease L-PSP 18 133 1.2E-17 T 09-03-2017 IPR006175 YjgF/YER057c/UK114 family UA74_RS02710 bf2f6c74c11941273399228ffad276b6 134 Gene3D G3DSA:3.30.1330.40 17 133 1.1E-28 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS02710 bf2f6c74c11941273399228ffad276b6 134 SUPERFAMILY SSF55298 20 133 1.48E-25 T 09-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_RS17245 c4f79594b21aa9fe31dfe752384a5771 89 SUPERFAMILY SSF47413 11 77 1.63E-15 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS17245 c4f79594b21aa9fe31dfe752384a5771 89 Pfam PF13560 Helix-turn-helix domain 16 75 3.4E-11 T 09-03-2017 UA74_RS17245 c4f79594b21aa9fe31dfe752384a5771 89 SMART SM00530 20 74 6.1E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS17245 c4f79594b21aa9fe31dfe752384a5771 89 Gene3D G3DSA:1.10.260.40 8 75 2.9E-23 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02095 f709905b42318aa9060cd2639b3acaf6 258 Pfam PF00483 Nucleotidyl transferase 8 246 1.8E-14 T 09-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_RS02095 f709905b42318aa9060cd2639b3acaf6 258 SUPERFAMILY SSF53448 5 249 7.43E-35 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS02095 f709905b42318aa9060cd2639b3acaf6 258 Gene3D G3DSA:3.90.550.10 5 247 4.2E-37 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS14085 eac4336f8429fef5b4b5de077db0ac47 225 SUPERFAMILY SSF53335 50 193 7.91E-23 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14085 eac4336f8429fef5b4b5de077db0ac47 225 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 80 133 2.8E-10 T 09-03-2017 UA74_RS14085 eac4336f8429fef5b4b5de077db0ac47 225 Gene3D G3DSA:3.40.50.150 47 197 7.4E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS09660 0d656a8dbf40aee1f7399bea549e22e4 425 Pfam PF01882 Protein of unknown function DUF58 197 280 2.7E-20 T 09-03-2017 IPR002881 Domain of unknown function DUF58 UA74_RS09835 47ff7e04fecd29de4d1a72331724728c 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 3.1E-10 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS09835 47ff7e04fecd29de4d1a72331724728c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.0E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS09835 47ff7e04fecd29de4d1a72331724728c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.0E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS09835 47ff7e04fecd29de4d1a72331724728c 212 SUPERFAMILY SSF46689 16 93 4.82E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS09835 47ff7e04fecd29de4d1a72331724728c 212 Gene3D G3DSA:1.10.357.10 18 209 1.4E-33 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS09835 47ff7e04fecd29de4d1a72331724728c 212 SUPERFAMILY SSF48498 93 199 4.2E-9 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS22635 ca8ea3bdd59d2e0303a2f4430abc9d20 280 SUPERFAMILY SSF47413 6 62 1.07E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22635 ca8ea3bdd59d2e0303a2f4430abc9d20 280 Gene3D G3DSA:1.10.260.40 7 61 1.8E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22635 ca8ea3bdd59d2e0303a2f4430abc9d20 280 SMART SM00530 15 68 0.0055 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS22635 ca8ea3bdd59d2e0303a2f4430abc9d20 280 Pfam PF13560 Helix-turn-helix domain 12 63 2.3E-13 T 09-03-2017 UA74_RS15575 d842535fa4c59966418862a6e8b4d24c 316 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 43 294 2.2E-67 T 09-03-2017 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 UA74_RS15575 d842535fa4c59966418862a6e8b4d24c 316 SUPERFAMILY SSF56112 38 296 2.72E-27 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS00325 d277e235f604049c20f51f6360b63b19 86 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 2.5E-32 T 09-03-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 UA74_RS00325 d277e235f604049c20f51f6360b63b19 86 SUPERFAMILY SSF143011 1 83 1.44E-26 T 09-03-2017 UA74_RS00325 d277e235f604049c20f51f6360b63b19 86 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 1.9E-37 T 09-03-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 UA74_RS24250 b95922d4b1e8f1ab2636f30a70598821 142 Gene3D G3DSA:2.30.110.10 3 135 1.1E-31 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS24250 b95922d4b1e8f1ab2636f30a70598821 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 133 6.2E-35 T 09-03-2017 IPR019920 F420-binding domain, putative UA74_RS24250 b95922d4b1e8f1ab2636f30a70598821 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 90 1.1E-15 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS24250 b95922d4b1e8f1ab2636f30a70598821 142 SUPERFAMILY SSF50475 2 133 3.93E-26 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS26570 f1932fe86acfac9820fe625616db4b28 378 Gene3D G3DSA:3.40.50.300 1 236 1.4E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26570 f1932fe86acfac9820fe625616db4b28 378 Pfam PF00005 ABC transporter 19 163 2.9E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS26570 f1932fe86acfac9820fe625616db4b28 378 SUPERFAMILY SSF52540 2 239 3.08E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26570 f1932fe86acfac9820fe625616db4b28 378 SMART SM00382 27 212 9.4E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS26570 f1932fe86acfac9820fe625616db4b28 378 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 SUPERFAMILY SSF56420 3 166 3.4E-50 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 Gene3D G3DSA:3.90.45.10 5 169 1.4E-54 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 Hamap MF_00163 Peptide deformylase [def]. 2 160 26.868 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 PIRSF PIRSF004749 1 170 2.5E-43 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 87 98 2.3E-30 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 118 147 2.3E-30 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 33 62 2.3E-30 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 99 117 2.3E-30 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 Pfam PF01327 Polypeptide deformylase 4 148 1.5E-41 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS12370 ca14687659b5371012f61c19bf6724f2 181 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 7 154 8.0E-36 T 09-03-2017 IPR023635 Peptide deformylase UA74_RS23515 c57ea0e7367482223a27a63ea5c124f7 317 Gene3D G3DSA:2.60.120.200 53 283 2.7E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS23515 c57ea0e7367482223a27a63ea5c124f7 317 SUPERFAMILY SSF49899 53 283 3.03E-23 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS10240 ae0ce6709c7d9130832b369720cd6b0b 433 Gene3D G3DSA:3.40.50.1820 270 360 3.5E-8 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10240 ae0ce6709c7d9130832b369720cd6b0b 433 Gene3D G3DSA:3.40.50.1820 125 154 3.5E-8 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10240 ae0ce6709c7d9130832b369720cd6b0b 433 SUPERFAMILY SSF53474 298 375 2.1E-6 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10240 ae0ce6709c7d9130832b369720cd6b0b 433 SUPERFAMILY SSF53474 125 207 2.1E-6 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS10240 ae0ce6709c7d9130832b369720cd6b0b 433 Pfam PF06259 Alpha/beta hydrolase 273 366 7.7E-25 T 09-03-2017 IPR010427 Protein of unknown function DUF1023 UA74_RS10240 ae0ce6709c7d9130832b369720cd6b0b 433 Pfam PF06259 Alpha/beta hydrolase 147 253 4.5E-21 T 09-03-2017 IPR010427 Protein of unknown function DUF1023 UA74_RS15435 97f6e0f791c1e5ea729f3cdcacb3c864 200 SUPERFAMILY SSF53597 2 196 1.07E-26 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS15435 97f6e0f791c1e5ea729f3cdcacb3c864 200 Pfam PF01872 RibD C-terminal domain 2 187 7.6E-10 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS15435 97f6e0f791c1e5ea729f3cdcacb3c864 200 Gene3D G3DSA:3.40.430.10 3 195 2.5E-26 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS20825 6a6e52d91e6108414fd648cbe827090a 120 Pfam PF05488 PAAR motif 40 108 6.1E-13 T 09-03-2017 IPR008727 PAAR motif UA74_RS20825 6a6e52d91e6108414fd648cbe827090a 120 Pfam PF05488 PAAR motif 80 119 1.2E-7 T 09-03-2017 IPR008727 PAAR motif UA74_RS19885 1d46dc980e3d0a7d35266f1901d0eb18 320 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 314 4.8E-112 T 09-03-2017 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family UA74_RS19885 1d46dc980e3d0a7d35266f1901d0eb18 320 SUPERFAMILY SSF56059 131 316 2.43E-12 T 09-03-2017 UA74_RS05095 fdd6f3594cbf4169f5c522a85c962b3c 343 Gene3D G3DSA:1.25.40.10 99 211 3.0E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05095 fdd6f3594cbf4169f5c522a85c962b3c 343 Gene3D G3DSA:1.25.40.10 265 304 3.0E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS05095 fdd6f3594cbf4169f5c522a85c962b3c 343 SUPERFAMILY SSF48452 98 207 3.04E-6 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS29360 0326220208af595a3cb336de09430fd7 61 Pfam PF11273 Protein of unknown function (DUF3073) 2 60 1.4E-23 T 09-03-2017 IPR021426 Protein of unknown function DUF3073 UA74_RS29050 a4d4c53678ce0f7b1c5480b4d1a3f579 302 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 64 207 6.9E-45 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS29050 a4d4c53678ce0f7b1c5480b4d1a3f579 302 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 64 207 5.3E-41 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS26940 35f143f4deec33bd4c01a2c51491743b 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 296 3.8E-37 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS21780 0dc3a66477651a48bcc3823e7501fdd6 248 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 24 156 3.8E-21 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_RS21780 0dc3a66477651a48bcc3823e7501fdd6 248 SUPERFAMILY SSF55718 165 247 2.0E-9 T 09-03-2017 IPR003033 SCP2 sterol-binding domain UA74_RS21780 0dc3a66477651a48bcc3823e7501fdd6 248 Gene3D G3DSA:1.20.120.450 16 130 7.7E-6 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS21780 0dc3a66477651a48bcc3823e7501fdd6 248 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 24 231 7.2E-26 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_RS21780 0dc3a66477651a48bcc3823e7501fdd6 248 SUPERFAMILY SSF109854 15 162 6.59E-37 T 09-03-2017 UA74_RS00275 a7548df9c8977cf38fbd35599cfb686c 320 Gene3D G3DSA:3.20.20.100 9 316 2.6E-90 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS00275 a7548df9c8977cf38fbd35599cfb686c 320 SUPERFAMILY SSF51430 2 316 7.6E-89 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS00275 a7548df9c8977cf38fbd35599cfb686c 320 Pfam PF00248 Aldo/keto reductase family 16 314 1.1E-64 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS21090 e27172d6da22a70441ebf26b039db0e7 384 SUPERFAMILY SSF50129 7 167 2.6E-23 T 09-03-2017 IPR011032 GroES-like UA74_RS21090 e27172d6da22a70441ebf26b039db0e7 384 Gene3D G3DSA:3.90.180.10 6 180 6.7E-26 T 09-03-2017 IPR011032 GroES-like UA74_RS21090 e27172d6da22a70441ebf26b039db0e7 384 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 95 3.3E-10 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS23655 982f331e328ce4d2359a46c08f20f1b2 158 Pfam PF11774 Lsr2 1 94 1.0E-23 T 09-03-2017 IPR024412 Lsr2 UA74_RS23655 982f331e328ce4d2359a46c08f20f1b2 158 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 90 5.0E-14 T 09-03-2017 IPR024412 Lsr2 UA74_RS16030 dd1fb7c790650214431640cf7ed9397e 1025 Gene3D G3DSA:3.40.50.300 255 432 1.2E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16030 dd1fb7c790650214431640cf7ed9397e 1025 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 8 686 7.7E-119 T 09-03-2017 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 UA74_RS16030 dd1fb7c790650214431640cf7ed9397e 1025 SMART SM00487 257 448 2.3E-15 T 09-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_RS16030 dd1fb7c790650214431640cf7ed9397e 1025 Pfam PF04851 Type III restriction enzyme, res subunit 261 420 3.0E-14 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_RS16030 dd1fb7c790650214431640cf7ed9397e 1025 SUPERFAMILY SSF52540 232 459 2.13E-25 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16030 dd1fb7c790650214431640cf7ed9397e 1025 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 11 202 8.4E-21 T 09-03-2017 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 UA74_RS28650 4bd1444582d5835632d16736ddde1a7b 255 SUPERFAMILY SSF161098 49 238 9.81E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS28650 4bd1444582d5835632d16736ddde1a7b 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 227 1.9E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS28650 4bd1444582d5835632d16736ddde1a7b 255 Gene3D G3DSA:1.10.3720.10 47 244 1.1E-16 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS04275 773d6770a46919a9f4ebc9a7a16c3b44 480 Pfam PF06114 Domain of unknown function (DUF955) 210 304 1.5E-9 T 09-03-2017 IPR010359 HTH domain, IrrE-type UA74_RS04275 773d6770a46919a9f4ebc9a7a16c3b44 480 SUPERFAMILY SSF47413 9 75 8.16E-18 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS04275 773d6770a46919a9f4ebc9a7a16c3b44 480 Pfam PF13560 Helix-turn-helix domain 12 70 4.1E-15 T 09-03-2017 UA74_RS04275 773d6770a46919a9f4ebc9a7a16c3b44 480 SMART SM00530 15 70 2.6E-15 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS04275 773d6770a46919a9f4ebc9a7a16c3b44 480 Gene3D G3DSA:1.10.260.40 11 75 3.3E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS19455 aac1c9c9ac4e32192e3d45a295a2bcd3 275 Gene3D G3DSA:3.60.15.10 59 258 6.0E-28 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS19455 aac1c9c9ac4e32192e3d45a295a2bcd3 275 SUPERFAMILY SSF56281 57 241 1.27E-24 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS27230 4f69e0de3eb1ddfe6e11193a153f25ad 296 SUPERFAMILY SSF51658 59 294 6.36E-37 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27230 4f69e0de3eb1ddfe6e11193a153f25ad 296 Gene3D G3DSA:3.20.20.150 58 295 1.7E-47 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS27230 4f69e0de3eb1ddfe6e11193a153f25ad 296 Pfam PF01261 Xylose isomerase-like TIM barrel 78 252 9.8E-17 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS02500 9d49c14e8cb395134670ce7bd5c9814b 106 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 17 105 1.3E-43 T 09-03-2017 IPR009359 Phenylacetic acid degradation B UA74_RS02500 9d49c14e8cb395134670ce7bd5c9814b 106 Pfam PF06243 Phenylacetic acid degradation B 17 102 6.7E-38 T 09-03-2017 IPR009359 Phenylacetic acid degradation B UA74_RS02500 9d49c14e8cb395134670ce7bd5c9814b 106 PIRSF PIRSF030200 5 106 1.7E-42 T 09-03-2017 IPR009359 Phenylacetic acid degradation B UA74_RS21480 3047b1f7ebb613e3a915d5d7543ba91c 504 Pfam PF08386 TAP-like protein 412 502 1.8E-19 T 09-03-2017 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal UA74_RS21480 3047b1f7ebb613e3a915d5d7543ba91c 504 SUPERFAMILY SSF53474 201 255 3.46E-18 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21480 3047b1f7ebb613e3a915d5d7543ba91c 504 SUPERFAMILY SSF53474 376 490 3.46E-18 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21480 3047b1f7ebb613e3a915d5d7543ba91c 504 SUPERFAMILY SSF53474 106 161 3.46E-18 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21480 3047b1f7ebb613e3a915d5d7543ba91c 504 Gene3D G3DSA:3.40.50.1820 75 160 3.6E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21480 3047b1f7ebb613e3a915d5d7543ba91c 504 Gene3D G3DSA:3.40.50.1820 369 490 3.6E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS21480 3047b1f7ebb613e3a915d5d7543ba91c 504 Gene3D G3DSA:3.40.50.1820 199 323 3.6E-42 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS06025 02eb7f0c15658fb5ef91c798e907ad38 247 Gene3D G3DSA:2.170.16.10 1 138 1.3E-22 T 09-03-2017 IPR028992 Hedgehog/Intein (Hint) domain UA74_RS06025 02eb7f0c15658fb5ef91c798e907ad38 247 SUPERFAMILY SSF51294 1 135 3.01E-18 T 09-03-2017 IPR028992 Hedgehog/Intein (Hint) domain UA74_RS06025 02eb7f0c15658fb5ef91c798e907ad38 247 SMART SM00306 1 94 2.9E-4 T 09-03-2017 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS06025 02eb7f0c15658fb5ef91c798e907ad38 247 Pfam PF07591 Pretoxin HINT domain 3 137 1.4E-19 T 09-03-2017 UA74_RS25430 da6f56972da539bdc49519c78deebb12 193 SUPERFAMILY SSF143990 29 190 1.14E-43 T 09-03-2017 UA74_RS25430 da6f56972da539bdc49519c78deebb12 193 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 37 188 1.2E-46 T 09-03-2017 IPR012816 NADAR UA74_RS25430 da6f56972da539bdc49519c78deebb12 193 Pfam PF08719 Domain of unknown function (DUF1768) 41 188 4.0E-49 T 09-03-2017 IPR012816 NADAR UA74_RS08700 1e200e33883bbe843a10844a686491b6 434 Pfam PF03993 Domain of Unknown Function (DUF349) 199 271 3.0E-19 T 09-03-2017 IPR007139 Protein of unknown function DUF349 UA74_RS08700 1e200e33883bbe843a10844a686491b6 434 Pfam PF03993 Domain of Unknown Function (DUF349) 277 349 1.2E-20 T 09-03-2017 IPR007139 Protein of unknown function DUF349 UA74_RS08700 1e200e33883bbe843a10844a686491b6 434 Pfam PF03993 Domain of Unknown Function (DUF349) 123 195 4.6E-13 T 09-03-2017 IPR007139 Protein of unknown function DUF349 UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 SUPERFAMILY SSF51604 133 374 1.03E-74 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 Gene3D G3DSA:3.20.20.120 149 369 3.9E-78 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 47 145 3.7E-14 T 09-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 212 243 - T 09-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 SUPERFAMILY SSF54826 16 146 6.23E-29 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 Gene3D G3DSA:3.30.390.10 16 148 4.0E-42 T 09-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 Pfam PF13378 Enolase C-terminal domain-like 171 372 6.6E-64 T 09-03-2017 IPR029065 Enolase C-terminal domain-like UA74_RS05615 33c4b27d0e11b592309b9955e9432655 387 SMART SM00922 166 262 2.3E-25 T 09-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_RS13575 a0be26de18822621289970bba1046d7e 140 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 132 1.1E-28 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS13575 a0be26de18822621289970bba1046d7e 140 Pfam PF04075 Domain of unknown function (DUF385) 10 133 8.3E-38 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS13575 a0be26de18822621289970bba1046d7e 140 SUPERFAMILY SSF50475 24 118 7.66E-8 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS13575 a0be26de18822621289970bba1046d7e 140 Gene3D G3DSA:2.30.110.10 28 115 1.3E-10 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS17705 442a51de10c2aeabc3017bb3038c252e 303 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 26 286 4.0E-70 T 09-03-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 UA74_RS17705 442a51de10c2aeabc3017bb3038c252e 303 SUPERFAMILY SSF53335 25 302 3.07E-60 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17705 442a51de10c2aeabc3017bb3038c252e 303 Gene3D G3DSA:3.40.50.150 33 223 3.0E-16 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17705 442a51de10c2aeabc3017bb3038c252e 303 Pfam PF04072 Leucine carboxyl methyltransferase 29 208 3.5E-52 T 09-03-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 UA74_RS23160 4e46bcdaee4286193d893390b8cedff0 257 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 45 7.5E-8 T 09-03-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_RS23160 4e46bcdaee4286193d893390b8cedff0 257 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 5 151 1.9E-41 T 09-03-2017 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 UA74_RS23160 4e46bcdaee4286193d893390b8cedff0 257 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 237 3.6E-43 T 09-03-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_RS30085 3482c5e73bcd59de48cded3d77d4bdf2 413 SUPERFAMILY SSF52518 49 401 4.32E-95 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS30085 3482c5e73bcd59de48cded3d77d4bdf2 413 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 52 398 1.7E-126 T 09-03-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UA74_RS30085 3482c5e73bcd59de48cded3d77d4bdf2 413 Pfam PF00676 Dehydrogenase E1 component 82 361 4.2E-70 T 09-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 UA74_RS30085 3482c5e73bcd59de48cded3d77d4bdf2 413 Gene3D G3DSA:3.40.50.970 43 398 2.1E-125 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS00400 3e74e4dc1205fdfaa3d5ab6319c741c2 539 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 48 457 4.1E-58 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS00400 3e74e4dc1205fdfaa3d5ab6319c741c2 539 Pfam PF00474 Sodium:solute symporter family 48 457 1.0E-93 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS29970 64262c0718bf7266f7ccb36cad8b6ea9 379 Pfam PF04230 Polysaccharide pyruvyl transferase 20 321 3.4E-17 T 09-03-2017 IPR007345 Polysaccharide pyruvyl transferase UA74_RS14455 42ed946d0c2856827089e519b929463d 182 SUPERFAMILY SSF46689 5 65 2.0E-11 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14455 42ed946d0c2856827089e519b929463d 182 Gene3D G3DSA:1.10.357.10 4 174 5.3E-33 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS14455 42ed946d0c2856827089e519b929463d 182 SUPERFAMILY SSF48498 78 174 2.52E-5 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS14455 42ed946d0c2856827089e519b929463d 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 5.6E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS01205 331279879684af22030cfa677f5880a5 278 SUPERFAMILY SSF55811 143 212 5.95E-15 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS01205 331279879684af22030cfa677f5880a5 278 SUPERFAMILY SSF55811 89 100 5.95E-15 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS01205 331279879684af22030cfa677f5880a5 278 SUPERFAMILY SSF55811 6 61 5.95E-15 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS01205 331279879684af22030cfa677f5880a5 278 Gene3D G3DSA:3.90.79.10 9 100 4.3E-17 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS01205 331279879684af22030cfa677f5880a5 278 Gene3D G3DSA:3.90.79.10 143 198 4.3E-17 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS11805 e064ea56303a31dc35c12087a65046bf 154 Pfam PF13466 STAS domain 52 132 3.1E-11 T 09-03-2017 IPR002645 STAS domain UA74_RS11805 e064ea56303a31dc35c12087a65046bf 154 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 44 134 7.4E-17 T 09-03-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UA74_RS11805 e064ea56303a31dc35c12087a65046bf 154 Gene3D G3DSA:3.30.750.24 45 146 4.9E-21 T 09-03-2017 IPR002645 STAS domain UA74_RS11805 e064ea56303a31dc35c12087a65046bf 154 SUPERFAMILY SSF52091 45 146 1.59E-17 T 09-03-2017 IPR002645 STAS domain UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 37 480 1.4E-147 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 09-03-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 7.2E-97 T 09-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 SUPERFAMILY SSF81442 26 535 2.35E-174 T 09-03-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 Gene3D G3DSA:1.20.210.10 21 548 4.1E-191 T 09-03-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS06240 04b9bd97b02b4660cbc3939f84f452a1 594 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 9.0E-215 T 09-03-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UA74_RS14655 31a9f4ee0d2315e447288c40f8f7c4ed 423 Pfam PF02638 Glycosyl hydrolase-like 10 56 368 6.1E-91 T 09-03-2017 IPR003790 Glycosyl hydrolase-like 10 UA74_RS14655 31a9f4ee0d2315e447288c40f8f7c4ed 423 Gene3D G3DSA:3.20.20.70 81 281 2.1E-5 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS14655 31a9f4ee0d2315e447288c40f8f7c4ed 423 SUPERFAMILY SSF51445 84 349 9.31E-25 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS22730 92b7513ce0f28f14eb5115b059ae23f7 309 SUPERFAMILY SSF161098 88 290 4.58E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22730 92b7513ce0f28f14eb5115b059ae23f7 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 305 4.5E-37 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS22730 92b7513ce0f28f14eb5115b059ae23f7 309 Gene3D G3DSA:1.10.3720.10 88 296 1.3E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19285 1859ed11780c01ffd0e3832bf4aed647 306 Pfam PF13732 Domain of unknown function (DUF4162) 228 300 6.7E-7 T 09-03-2017 IPR025302 Domain of unknown function DUF4162 UA74_RS19285 1859ed11780c01ffd0e3832bf4aed647 306 SMART SM00382 40 225 9.8E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS19285 1859ed11780c01ffd0e3832bf4aed647 306 Pfam PF00005 ABC transporter 32 169 1.0E-24 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS19285 1859ed11780c01ffd0e3832bf4aed647 306 Gene3D G3DSA:3.40.50.300 11 236 3.1E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19285 1859ed11780c01ffd0e3832bf4aed647 306 SUPERFAMILY SSF52540 15 228 3.52E-53 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS17330 5f58b22024104e84537cfd3f8cf7715a 148 SUPERFAMILY SSF51182 17 142 7.18E-38 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS17330 5f58b22024104e84537cfd3f8cf7715a 148 Pfam PF05523 WxcM-like, C-terminal 17 143 7.8E-48 T 09-03-2017 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 UA74_RS17330 5f58b22024104e84537cfd3f8cf7715a 148 Gene3D G3DSA:2.60.120.10 56 140 5.1E-6 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS13520 d4da8b8f8f2bb1230e68dfd6625d778a 384 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 79 200 1.1E-28 T 09-03-2017 UA74_RS13520 d4da8b8f8f2bb1230e68dfd6625d778a 384 SUPERFAMILY SSF53335 82 199 5.79E-31 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13520 d4da8b8f8f2bb1230e68dfd6625d778a 384 Gene3D G3DSA:3.40.50.150 7 235 2.9E-52 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS11570 1dc505e19a1221cdc9c3178d8ef8dda6 426 SUPERFAMILY SSF54001 286 415 2.7E-34 T 09-03-2017 UA74_RS11570 1dc505e19a1221cdc9c3178d8ef8dda6 426 Gene3D G3DSA:3.90.1720.10 284 417 8.0E-41 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain UA74_RS11570 1dc505e19a1221cdc9c3178d8ef8dda6 426 Pfam PF00877 NlpC/P60 family 302 423 8.8E-28 T 09-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain UA74_RS24070 d1be1143a7f520b0433e8b0ec1371505 245 SUPERFAMILY SSF161098 46 240 3.53E-25 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24070 d1be1143a7f520b0433e8b0ec1371505 245 Gene3D G3DSA:1.10.3720.10 44 241 8.0E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS24070 d1be1143a7f520b0433e8b0ec1371505 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 240 2.9E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS25750 4e5d2e80c6ec2429e71819c558558cc6 553 Pfam PF03814 Potassium-transporting ATPase A subunit 14 552 5.3E-213 T 09-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_RS25750 4e5d2e80c6ec2429e71819c558558cc6 553 PIRSF PIRSF001294 4 553 4.3E-201 T 09-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_RS25750 4e5d2e80c6ec2429e71819c558558cc6 553 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 552 4.8E-192 T 09-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_RS25750 4e5d2e80c6ec2429e71819c558558cc6 553 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 553 31.056 T 09-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_RS18210 2ffc375e41ff105b1bec7bafc190b152 264 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 146 1.7E-24 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_RS18210 2ffc375e41ff105b1bec7bafc190b152 264 SUPERFAMILY SSF102588 3 223 1.7E-51 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS18210 2ffc375e41ff105b1bec7bafc190b152 264 Gene3D G3DSA:3.40.50.10320 3 264 2.2E-62 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS00660 92c121210ac543d3648bbf500eac3dcd 397 Gene3D G3DSA:3.50.50.60 136 214 8.3E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS00660 92c121210ac543d3648bbf500eac3dcd 397 Gene3D G3DSA:3.50.50.60 2 75 8.3E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS00660 92c121210ac543d3648bbf500eac3dcd 397 Gene3D G3DSA:3.50.50.60 350 390 8.3E-31 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS00660 92c121210ac543d3648bbf500eac3dcd 397 Gene3D G3DSA:3.30.9.10 85 135 5.5E-7 T 09-03-2017 UA74_RS00660 92c121210ac543d3648bbf500eac3dcd 397 Pfam PF01266 FAD dependent oxidoreductase 3 389 1.4E-60 T 09-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_RS00660 92c121210ac543d3648bbf500eac3dcd 397 SUPERFAMILY SSF51905 2 215 1.12E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS00660 92c121210ac543d3648bbf500eac3dcd 397 SUPERFAMILY SSF51905 350 392 1.12E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS28505 1edb7e58b2e39514129d2150b5efd2c6 1024 SUPERFAMILY SSF55874 43 132 4.52E-10 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS28505 1edb7e58b2e39514129d2150b5efd2c6 1024 Gene3D G3DSA:3.30.565.10 42 223 6.1E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS04685 0210418cabe13995fff3525ad781cc63 143 Pfam PF00149 Calcineurin-like phosphoesterase 3 143 1.9E-7 T 09-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 UA74_RS04685 0210418cabe13995fff3525ad781cc63 143 SUPERFAMILY SSF56300 2 143 1.34E-22 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS04685 0210418cabe13995fff3525ad781cc63 143 Gene3D G3DSA:3.60.21.10 2 143 1.0E-15 T 09-03-2017 IPR029052 Metallo-dependent phosphatase-like UA74_RS16305 cc901b32c21d0dfb439e09b3ac2f29db 628 Pfam PF01935 Domain of unknown function DUF87 252 315 7.8E-8 T 09-03-2017 IPR002789 Helicase HerA, central domain UA74_RS16305 cc901b32c21d0dfb439e09b3ac2f29db 628 SUPERFAMILY SSF52540 209 572 1.22E-41 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16305 cc901b32c21d0dfb439e09b3ac2f29db 628 Gene3D G3DSA:3.40.50.300 419 548 6.7E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS16305 cc901b32c21d0dfb439e09b3ac2f29db 628 Gene3D G3DSA:3.40.50.300 246 319 6.7E-22 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19230 ec8d5d7632b1d3a6ee3aa153c0360ae7 118 Gene3D G3DSA:3.30.479.10 16 72 7.9E-5 T 09-03-2017 UA74_RS19230 ec8d5d7632b1d3a6ee3aa153c0360ae7 118 SUPERFAMILY SSF55620 12 70 7.23E-5 T 09-03-2017 UA74_RS18555 a0b5359de15f07fbc4cb533f4d6b1b30 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.1E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS04660 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 SUPERFAMILY SSF53850 43 397 7.67E-61 T 09-03-2017 UA74_RS04660 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 Pfam PF01547 Bacterial extracellular solute-binding protein 78 329 7.7E-23 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS04660 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 Gene3D G3DSA:3.40.190.10 53 169 5.6E-12 T 09-03-2017 UA74_RS04660 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 Gene3D G3DSA:3.40.190.10 170 359 2.4E-47 T 09-03-2017 UA74_RS00060 9a798d8a2000177c66f36269f365906e 279 Pfam PF13649 Methyltransferase domain 66 160 1.5E-11 T 09-03-2017 UA74_RS00060 9a798d8a2000177c66f36269f365906e 279 SUPERFAMILY SSF53335 28 278 9.07E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00060 9a798d8a2000177c66f36269f365906e 279 Gene3D G3DSA:3.40.50.150 205 237 3.0E-21 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS00060 9a798d8a2000177c66f36269f365906e 279 Gene3D G3DSA:3.40.50.150 54 169 3.0E-21 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS26275 bdad4423d81bfe3f3464b7d53113d4b4 68 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 40 8.2E-14 T 09-03-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB UA74_RS29890 f311077a06458282047376340cc77d98 761 Pfam PF13183 4Fe-4S dicluster domain 296 409 2.0E-13 T 09-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_RS29890 f311077a06458282047376340cc77d98 761 Pfam PF02754 Cysteine-rich domain 478 569 2.0E-14 T 09-03-2017 IPR004017 Cysteine-rich domain UA74_RS29890 f311077a06458282047376340cc77d98 761 Pfam PF02754 Cysteine-rich domain 608 694 2.5E-16 T 09-03-2017 IPR004017 Cysteine-rich domain UA74_RS29890 f311077a06458282047376340cc77d98 761 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 395 406 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS29890 f311077a06458282047376340cc77d98 761 SUPERFAMILY SSF46548 376 423 1.71E-21 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_RS29890 f311077a06458282047376340cc77d98 761 SUPERFAMILY SSF46548 281 320 1.71E-21 T 09-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_RS29890 f311077a06458282047376340cc77d98 761 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 299 310 - T 09-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_RS29890 f311077a06458282047376340cc77d98 761 Gene3D G3DSA:1.10.1060.10 271 331 3.1E-31 T 09-03-2017 UA74_RS29890 f311077a06458282047376340cc77d98 761 Gene3D G3DSA:1.10.1060.10 373 423 3.1E-31 T 09-03-2017 UA74_RS20790 ec33e65f671d5eb6bbe79c8a3df4bef5 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 324 3.5E-39 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS29705 7e82de9c661b343ac57c52c14199940c 774 Pfam PF02687 FtsX-like permease family 194 307 2.5E-7 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS24820 d5739061c9558ba3fe4056b2de7914ed 68 Gene3D G3DSA:2.40.50.140 1 52 4.8E-4 T 09-03-2017 IPR012340 Nucleic acid-binding, OB-fold UA74_RS13140 14c08d6471a1296f66ea9cb2201210a1 492 Pfam PF13450 NAD(P)-binding Rossmann-like domain 14 65 9.7E-10 T 09-03-2017 UA74_RS13140 14c08d6471a1296f66ea9cb2201210a1 492 SUPERFAMILY SSF51905 11 306 6.29E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS13140 14c08d6471a1296f66ea9cb2201210a1 492 SUPERFAMILY SSF51905 446 476 6.29E-30 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS13140 14c08d6471a1296f66ea9cb2201210a1 492 Gene3D G3DSA:3.40.50.720 11 61 3.7E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13140 14c08d6471a1296f66ea9cb2201210a1 492 Gene3D G3DSA:3.50.50.60 213 289 9.1E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS13140 14c08d6471a1296f66ea9cb2201210a1 492 Gene3D G3DSA:3.50.50.60 445 476 9.1E-8 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS09720 58d68b77d76c3f52b9f0f2ba3ea2b1fa 507 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 73 424 3.2E-113 T 09-03-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 UA74_RS09720 58d68b77d76c3f52b9f0f2ba3ea2b1fa 507 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 383 407 - T 09-03-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 UA74_RS09720 58d68b77d76c3f52b9f0f2ba3ea2b1fa 507 Pfam PF01098 Cell cycle protein 72 425 3.0E-112 T 09-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 UA74_RS06165 97942a4a38665f6de71e67df8d0f5a9e 367 Pfam PF07730 Histidine kinase 158 223 4.6E-11 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS06165 97942a4a38665f6de71e67df8d0f5a9e 367 SUPERFAMILY SSF55874 266 361 4.22E-13 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS06165 97942a4a38665f6de71e67df8d0f5a9e 367 Gene3D G3DSA:3.30.565.10 272 362 4.8E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08880 0b047ed206bb0a552349bb9b6063275e 466 PIRSF PIRSF002746 18 466 2.8E-139 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_RS08880 0b047ed206bb0a552349bb9b6063275e 466 Pfam PF02447 GntP family permease 24 465 1.2E-138 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_RS08880 0b047ed206bb0a552349bb9b6063275e 466 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 27 466 2.3E-129 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_RS25230 3d956c9dcbf186b8167467d988f7cd03 315 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 7 235 7.7E-92 T 09-03-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c UA74_RS25230 3d956c9dcbf186b8167467d988f7cd03 315 Gene3D G3DSA:3.20.20.30 11 314 1.0E-84 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS25230 3d956c9dcbf186b8167467d988f7cd03 315 Pfam PF00296 Luciferase-like monooxygenase 9 255 4.1E-53 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS25230 3d956c9dcbf186b8167467d988f7cd03 315 SUPERFAMILY SSF51679 5 314 1.22E-78 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS16385 c93ac3b4ba79525288f352cde5ccdbce 507 Pfam PF09660 Protein of unknown function (DUF2397) 12 497 2.5E-82 T 09-03-2017 IPR013493 Conserved hypothetical protein CHP02677 UA74_RS16385 c93ac3b4ba79525288f352cde5ccdbce 507 TIGRFAM TIGR02677 TIGR02677: TIGR02677 family protein 12 503 9.1E-66 T 09-03-2017 IPR013493 Conserved hypothetical protein CHP02677 UA74_RS22965 5e3a7eeaad1bd3271895c624badb01df 526 Pfam PF07690 Major Facilitator Superfamily 24 411 8.4E-45 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS22965 5e3a7eeaad1bd3271895c624badb01df 526 Gene3D G3DSA:1.20.1250.20 476 500 5.5E-15 T 09-03-2017 UA74_RS22965 5e3a7eeaad1bd3271895c624badb01df 526 Gene3D G3DSA:1.20.1250.20 17 197 2.4E-27 T 09-03-2017 UA74_RS22965 5e3a7eeaad1bd3271895c624badb01df 526 Gene3D G3DSA:1.20.1250.20 265 422 5.5E-15 T 09-03-2017 UA74_RS22965 5e3a7eeaad1bd3271895c624badb01df 526 SUPERFAMILY SSF103473 475 495 8.37E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22965 5e3a7eeaad1bd3271895c624badb01df 526 SUPERFAMILY SSF103473 8 202 8.37E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22965 5e3a7eeaad1bd3271895c624badb01df 526 SUPERFAMILY SSF103473 250 421 8.37E-60 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS21355 6bd9cbdea80db9d54af4e959d875d97e 328 Pfam PF14472 Domain of unknown function (DUF4429) 167 251 1.0E-9 T 09-03-2017 IPR027860 Domain of unknown function DUF4429 UA74_RS21355 6bd9cbdea80db9d54af4e959d875d97e 328 Pfam PF14472 Domain of unknown function (DUF4429) 39 131 3.9E-7 T 09-03-2017 IPR027860 Domain of unknown function DUF4429 UA74_RS21355 6bd9cbdea80db9d54af4e959d875d97e 328 Pfam PF09851 Short C-terminal domain 299 325 6.0E-8 T 09-03-2017 IPR018649 SHOCT domain UA74_RS00510 28bde7250d027955096f76eec7f91a7d 236 Gene3D G3DSA:3.20.180.10 145 227 1.0E-7 T 09-03-2017 IPR019595 Domain of unknown function DUF2470 UA74_RS00510 28bde7250d027955096f76eec7f91a7d 236 Pfam PF10615 Protein of unknown function (DUF2470) 151 223 2.2E-7 T 09-03-2017 IPR019595 Domain of unknown function DUF2470 UA74_RS00510 28bde7250d027955096f76eec7f91a7d 236 SUPERFAMILY SSF50475 21 232 1.22E-19 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 Gene3D G3DSA:3.40.190.10 246 279 6.4E-27 T 09-03-2017 UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 Gene3D G3DSA:3.40.190.10 55 140 6.4E-27 T 09-03-2017 UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 SMART SM00062 58 285 2.2E-53 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 59 279 3.9E-48 T 09-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 SUPERFAMILY SSF53850 1 21 7.69E-53 T 09-03-2017 UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 SUPERFAMILY SSF53850 48 279 7.69E-53 T 09-03-2017 UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 82 95 - T 09-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 UA74_RS08680 01004302377d00c46dd98e75c1d39ff4 297 Gene3D G3DSA:3.40.190.10 141 245 1.2E-23 T 09-03-2017 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 321 336 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 275 286 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 93 104 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 159 174 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 344 353 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 353 364 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 293 320 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 142 158 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 194 216 1.8E-45 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 SUPERFAMILY SSF48264 17 401 1.26E-79 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 Gene3D G3DSA:1.10.630.10 10 401 5.5E-103 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS22505 52849095b1c13cbee502e91d259231a9 411 Pfam PF00067 Cytochrome P450 209 375 6.4E-16 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS29940 bc02ba41f0ebfedf9e8d60bfd1c5ca97 224 Gene3D G3DSA:3.40.50.1000 91 210 1.4E-25 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29940 bc02ba41f0ebfedf9e8d60bfd1c5ca97 224 Gene3D G3DSA:3.40.50.1000 15 35 1.4E-25 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29940 bc02ba41f0ebfedf9e8d60bfd1c5ca97 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 190 1.2E-5 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS29940 bc02ba41f0ebfedf9e8d60bfd1c5ca97 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 86 197 4.8E-17 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29940 bc02ba41f0ebfedf9e8d60bfd1c5ca97 224 SUPERFAMILY SSF56784 12 34 1.2E-27 T 09-03-2017 IPR023214 HAD-like domain UA74_RS29940 bc02ba41f0ebfedf9e8d60bfd1c5ca97 224 SUPERFAMILY SSF56784 91 218 1.2E-27 T 09-03-2017 IPR023214 HAD-like domain UA74_RS25710 d24a76824f092ca1db8d2132e3cd3c81 262 Pfam PF12483 E3 Ubiquitin ligase 95 252 6.3E-26 T 09-03-2017 IPR022170 Mitochondrial ubiquitin ligase activator of NFKB 1 GO:0004842|GO:0007005 UA74_RS09655 08ed71f1fb10e809772aec5e92ae704c 813 Gene3D G3DSA:3.90.260.10 441 533 2.0E-21 T 09-03-2017 IPR002931 Transglutaminase-like UA74_RS09655 08ed71f1fb10e809772aec5e92ae704c 813 SUPERFAMILY SSF54001 400 534 2.52E-30 T 09-03-2017 UA74_RS09655 08ed71f1fb10e809772aec5e92ae704c 813 SMART SM00460 463 532 5.1E-17 T 09-03-2017 IPR002931 Transglutaminase-like UA74_RS09655 08ed71f1fb10e809772aec5e92ae704c 813 Pfam PF01841 Transglutaminase-like superfamily 414 530 7.0E-24 T 09-03-2017 IPR002931 Transglutaminase-like UA74_RS19190 fb34e19fdd1eb0d282154c494bf96038 98 SUPERFAMILY SSF140453 4 94 3.66E-6 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS19190 fb34e19fdd1eb0d282154c494bf96038 98 Gene3D G3DSA:1.10.287.1060 1 95 2.6E-5 T 09-03-2017 UA74_RS04365 d79377aebc2df18981642185e4923375 281 Pfam PF12730 ABC-2 family transporter protein 28 188 7.4E-13 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 UA74_RS20035 00d940e0047c5c75c943d8a1ec2414f3 262 Gene3D G3DSA:3.40.50.720 6 209 1.2E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20035 00d940e0047c5c75c943d8a1ec2414f3 262 Pfam PF13460 NAD(P)H-binding 9 181 1.8E-18 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20035 00d940e0047c5c75c943d8a1ec2414f3 262 SUPERFAMILY SSF51735 6 222 3.45E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS22360 32960a31ff5da611406c122951c18dd9 442 SUPERFAMILY SSF53850 89 432 2.05E-42 T 09-03-2017 UA74_RS22360 32960a31ff5da611406c122951c18dd9 442 Gene3D G3DSA:3.40.190.10 77 173 9.6E-8 T 09-03-2017 UA74_RS22360 32960a31ff5da611406c122951c18dd9 442 Gene3D G3DSA:3.40.190.10 174 370 2.2E-29 T 09-03-2017 UA74_RS22360 32960a31ff5da611406c122951c18dd9 442 Pfam PF13416 Bacterial extracellular solute-binding protein 74 371 1.1E-21 T 09-03-2017 UA74_RS20980 484c37d6accb84b0d4e122a3f976d5a8 275 Gene3D G3DSA:3.90.1200.10 160 257 2.1E-7 T 09-03-2017 UA74_RS20980 484c37d6accb84b0d4e122a3f976d5a8 275 SUPERFAMILY SSF56112 16 228 3.83E-16 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS28735 6b7efe7b0ee423a7d458878be201468a 88 Pfam PF04226 Transglycosylase associated protein 36 85 2.9E-7 T 09-03-2017 IPR007341 Transglycosylase-associated protein GO:0016021 UA74_RS16840 b4a40c64af3545d3335b7b038e62b2c3 122 Pfam PF12680 SnoaL-like domain 11 109 2.0E-9 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS16840 b4a40c64af3545d3335b7b038e62b2c3 122 Gene3D G3DSA:3.10.450.50 9 113 1.3E-11 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS16840 b4a40c64af3545d3335b7b038e62b2c3 122 SUPERFAMILY SSF54427 3 115 2.87E-14 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS17990 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Pfam PF05592 Bacterial alpha-L-rhamnosidase 353 881 2.1E-65 T 09-03-2017 IPR008902 Bacterial alpha-L-rhamnosidase UA74_RS17990 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Gene3D G3DSA:2.60.40.10 38 141 1.4E-8 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS17990 9a0b6d5b46bf6a548c9d6d63c501cc03 927 SUPERFAMILY SSF48208 464 883 3.83E-41 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS17990 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Gene3D G3DSA:2.60.120.260 344 455 3.9E-6 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS17990 9a0b6d5b46bf6a548c9d6d63c501cc03 927 SUPERFAMILY SSF49265 62 141 2.26E-6 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS17990 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 178 323 1.8E-13 T 09-03-2017 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal UA74_RS09945 a07a3ff1285751eec2d422ebcb50ae66 114 Pfam PF13601 Winged helix DNA-binding domain 24 101 5.7E-19 T 09-03-2017 IPR027395 Winged helix DNA-binding domain UA74_RS09945 a07a3ff1285751eec2d422ebcb50ae66 114 SUPERFAMILY SSF46785 8 97 3.82E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09945 a07a3ff1285751eec2d422ebcb50ae66 114 Gene3D G3DSA:1.10.10.10 10 101 7.7E-18 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 SUPERFAMILY SSF51905 2 163 2.91E-67 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 SUPERFAMILY SSF51905 255 347 2.91E-67 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 1.9E-44 T 09-03-2017 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 1.9E-44 T 09-03-2017 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.9E-44 T 09-03-2017 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 319 1.9E-44 T 09-03-2017 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 1.9E-44 T 09-03-2017 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 1.9E-44 T 09-03-2017 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 Pfam PF01494 FAD binding domain 2 332 2.1E-86 T 09-03-2017 IPR002938 FAD-binding domain GO:0071949 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 Gene3D G3DSA:3.50.50.60 266 305 1.2E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 Gene3D G3DSA:3.50.50.60 2 153 1.2E-55 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 Gene3D G3DSA:3.30.9.10 154 261 3.4E-9 T 09-03-2017 UA74_RS15515 e20594a3774889d10e0a2a70e9160fbd 477 Gene3D G3DSA:3.30.9.10 316 345 3.4E-9 T 09-03-2017 UA74_RS12120 51bbcf105a5b491d6b862b621a6613b5 141 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 7.2E-21 T 09-03-2017 IPR009293 Uncharacterised protein family UPF0478 UA74_RS27925 09b1156ae5a1184ac039b2651618e0c9 206 SUPERFAMILY SSF48256 88 178 5.76E-5 T 09-03-2017 IPR002020 Citrate synthase GO:0046912 UA74_RS27925 09b1156ae5a1184ac039b2651618e0c9 206 Pfam PF13707 RloB-like protein 25 194 4.5E-27 T 09-03-2017 IPR025591 RloB-like protein UA74_RS25565 6e3d5d64c4bc2994e4ff544b188fa4ba 216 Pfam PF04973 Nicotinamide mononucleotide transporter 17 196 3.0E-44 T 09-03-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 UA74_RS25565 6e3d5d64c4bc2994e4ff544b188fa4ba 216 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 17 199 1.8E-13 T 09-03-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 Gene3D G3DSA:1.20.1250.20 29 210 2.0E-38 T 09-03-2017 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 153 175 1.2E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 181 201 1.2E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 267 287 1.2E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 38 54 1.2E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 Gene3D G3DSA:1.20.1250.20 217 413 2.9E-32 T 09-03-2017 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 ProSitePatterns PS00216 Sugar transport proteins signature 1. 285 301 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 Pfam PF00083 Sugar (and other) transporter 265 408 3.7E-7 T 09-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 Pfam PF07690 Major Facilitator Superfamily 33 263 4.6E-32 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS05030 24425d5bd6a882373bff363916d08f43 457 SUPERFAMILY SSF103473 14 415 7.72E-77 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS18845 448ddedc015c14d7eb3c055e694ce5e7 293 Gene3D G3DSA:3.40.50.720 9 83 6.9E-13 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18845 448ddedc015c14d7eb3c055e694ce5e7 293 SUPERFAMILY SSF51735 70 253 1.21E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18845 448ddedc015c14d7eb3c055e694ce5e7 293 Gene3D G3DSA:3.40.50.720 84 253 4.0E-45 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18845 448ddedc015c14d7eb3c055e694ce5e7 293 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 284 7.9E-8 T 09-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 UA74_RS18845 448ddedc015c14d7eb3c055e694ce5e7 293 SUPERFAMILY SSF52283 10 99 2.43E-9 T 09-03-2017 UA74_RS18845 448ddedc015c14d7eb3c055e694ce5e7 293 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 77 253 1.7E-44 T 09-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_RS25990 d021258b47b13c738ee44d7b4f92ff8e 228 Gene3D G3DSA:2.30.110.10 9 200 8.7E-65 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS25990 d021258b47b13c738ee44d7b4f92ff8e 228 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 35 178 9.7E-43 T 09-03-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related UA74_RS25990 d021258b47b13c738ee44d7b4f92ff8e 228 SUPERFAMILY SSF50475 15 200 8.45E-52 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 Gene3D G3DSA:3.40.50.300 2 181 6.4E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 Gene3D G3DSA:3.40.50.300 453 469 6.4E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 Gene3D G3DSA:3.40.50.300 885 1023 6.4E-33 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 SUPERFAMILY SSF52540 20 96 1.7E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 SUPERFAMILY SSF52540 868 1011 1.7E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 SUPERFAMILY SSF52540 148 217 1.7E-26 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 Pfam PF13558 Putative exonuclease SbcCD, C subunit 925 986 3.8E-11 T 09-03-2017 UA74_RS04215 4a14949c282cfcbc0aa182eaea942fc9 1028 Pfam PF13476 AAA domain 5 186 4.1E-21 T 09-03-2017 UA74_RS09325 a2849e6c2653b2263ccae0de2d14ac90 94 Gene3D G3DSA:3.30.1230.10 6 76 1.0E-22 T 09-03-2017 IPR007393 Domain of unknown function DUF448 UA74_RS09325 a2849e6c2653b2263ccae0de2d14ac90 94 Pfam PF04296 Protein of unknown function (DUF448) 12 81 2.8E-21 T 09-03-2017 IPR007393 Domain of unknown function DUF448 UA74_RS09325 a2849e6c2653b2263ccae0de2d14ac90 94 SUPERFAMILY SSF64376 8 85 1.27E-20 T 09-03-2017 IPR007393 Domain of unknown function DUF448 UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 Pfam PF00107 Zinc-binding dehydrogenase 185 312 5.1E-22 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 Gene3D G3DSA:3.40.50.720 178 296 1.9E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 09-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 Gene3D G3DSA:3.90.180.10 11 177 2.4E-43 T 09-03-2017 IPR011032 GroES-like UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 144 1.0E-24 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 SUPERFAMILY SSF51735 150 310 1.21E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 SUPERFAMILY SSF50129 11 184 5.02E-38 T 09-03-2017 IPR011032 GroES-like UA74_RS14625 2743ce351ca4fb39472eec53bae1adbd 354 SMART SM00829 19 328 2.0E-6 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS09590 4e1acc2bbc2e6ee822b5b0be7bef1c4c 170 Pfam PF00583 Acetyltransferase (GNAT) family 50 121 2.9E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS09590 4e1acc2bbc2e6ee822b5b0be7bef1c4c 170 SUPERFAMILY SSF55729 7 128 6.52E-22 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09590 4e1acc2bbc2e6ee822b5b0be7bef1c4c 170 Gene3D G3DSA:3.40.630.30 9 145 3.7E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 TIGRFAM TIGR00835 agcS: amino acid carrier protein 56 504 1.4E-107 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 Pfam PF01235 Sodium:alanine symporter family 92 512 6.0E-126 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 PRINTS PR00175 Sodium/alanine symporter signature 267 286 9.9E-41 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 PRINTS PR00175 Sodium/alanine symporter signature 412 434 9.9E-41 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 PRINTS PR00175 Sodium/alanine symporter signature 128 150 9.9E-41 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 PRINTS PR00175 Sodium/alanine symporter signature 239 257 9.9E-41 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 PRINTS PR00175 Sodium/alanine symporter signature 357 375 9.9E-41 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS29770 d964057359cde03874d70354d3c54c9f 515 PRINTS PR00175 Sodium/alanine symporter signature 473 493 9.9E-41 T 09-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_RS18230 eef2cd3aed22132d70d5230c2f56a265 528 Gene3D G3DSA:1.50.10.20 162 370 3.5E-14 T 09-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_RS18230 eef2cd3aed22132d70d5230c2f56a265 528 SUPERFAMILY SSF48239 137 322 1.69E-17 T 09-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_RS18230 eef2cd3aed22132d70d5230c2f56a265 528 Pfam PF01391 Collagen triple helix repeat (20 copies) 387 445 1.2E-8 T 09-03-2017 IPR008160 Collagen triple helix repeat UA74_RS19635 40a6039c2bb5f9a790e3aa1d8dbc4503 419 SUPERFAMILY SSF53850 21 416 1.03E-61 T 09-03-2017 UA74_RS19635 40a6039c2bb5f9a790e3aa1d8dbc4503 419 Gene3D G3DSA:3.40.190.10 41 162 1.7E-19 T 09-03-2017 UA74_RS19635 40a6039c2bb5f9a790e3aa1d8dbc4503 419 Gene3D G3DSA:3.40.190.10 163 343 5.3E-34 T 09-03-2017 UA74_RS19635 40a6039c2bb5f9a790e3aa1d8dbc4503 419 Pfam PF01547 Bacterial extracellular solute-binding protein 48 329 3.8E-28 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS15965 6da8996f262c92bacb2bcac8da96e60f 845 Pfam PF04851 Type III restriction enzyme, res subunit 14 119 6.1E-5 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_RS15965 6da8996f262c92bacb2bcac8da96e60f 845 Gene3D G3DSA:3.40.50.300 251 272 5.9E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15965 6da8996f262c92bacb2bcac8da96e60f 845 Gene3D G3DSA:3.40.50.300 11 127 5.9E-11 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15965 6da8996f262c92bacb2bcac8da96e60f 845 SUPERFAMILY SSF52540 10 136 1.42E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15965 6da8996f262c92bacb2bcac8da96e60f 845 SUPERFAMILY SSF52540 260 446 1.42E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19225 4d6bfbf29f3133bf16f5e2abef3b9c9a 77 Gene3D G3DSA:3.40.50.10540 2 62 4.6E-9 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS19225 4d6bfbf29f3133bf16f5e2abef3b9c9a 77 SUPERFAMILY SSF89796 2 61 1.57E-11 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS17210 8eb7ffde227dd1127cdcdf1554664cfe 298 Gene3D G3DSA:3.40.800.10 4 291 3.9E-43 T 09-03-2017 IPR023696 Ureohydrolase domain UA74_RS17210 8eb7ffde227dd1127cdcdf1554664cfe 298 SUPERFAMILY SSF52768 4 288 4.32E-43 T 09-03-2017 UA74_RS17210 8eb7ffde227dd1127cdcdf1554664cfe 298 Pfam PF00491 Arginase family 71 289 6.9E-23 T 09-03-2017 IPR006035 Ureohydrolase GO:0046872 UA74_RS05700 631b5d589c4b6c410e0cf2261d597a0f 328 SUPERFAMILY SSF53850 115 286 1.98E-10 T 09-03-2017 UA74_RS05700 631b5d589c4b6c410e0cf2261d597a0f 328 Gene3D G3DSA:3.40.190.10 131 234 6.9E-7 T 09-03-2017 UA74_RS05700 631b5d589c4b6c410e0cf2261d597a0f 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 71 328 5.5E-32 T 09-03-2017 IPR005064 Bordetella uptake gene GO:0030288 UA74_RS05700 631b5d589c4b6c410e0cf2261d597a0f 328 PIRSF PIRSF017082 1 328 2.7E-96 T 09-03-2017 IPR005064 Bordetella uptake gene GO:0030288 UA74_RS25415 160fb5de5d8f18d71ff7b5dca0a6b63d 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 4.0E-10 T 09-03-2017 IPR003743 C4-type zinc ribbon domain UA74_RS02575 596f0b58ba8a3496ec1f02260215da6f 458 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 58 73 - T 09-03-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02575 596f0b58ba8a3496ec1f02260215da6f 458 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 12 348 24.923 T 09-03-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02575 596f0b58ba8a3496ec1f02260215da6f 458 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 223 236 - T 09-03-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02575 596f0b58ba8a3496ec1f02260215da6f 458 Pfam PF00146 NADH dehydrogenase 19 341 9.5E-125 T 09-03-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS10890 e920b639217def9a87b9beb3c12da7a2 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 4 97 1.5E-13 T 09-03-2017 IPR008407 Branched-chain amino acid transport, AzlD UA74_RS15825 29b4b7c35bc02fe68fd6fd5203c04852 135 SUPERFAMILY SSF46785 7 126 1.15E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS15825 29b4b7c35bc02fe68fd6fd5203c04852 135 Gene3D G3DSA:1.10.10.10 4 126 5.0E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS27790 8b71648e1b71be2cb713ee525052749b 309 Pfam PF04657 Putative inner membrane exporter, YdcZ 166 300 4.4E-19 T 09-03-2017 IPR006750 Putative inner membrane exporter, YdcZ UA74_RS27790 8b71648e1b71be2cb713ee525052749b 309 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 150 1.3E-24 T 09-03-2017 IPR006750 Putative inner membrane exporter, YdcZ UA74_RS18370 db45cd5b82134ee9887f1f145e13d426 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 322 8.1E-45 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS02390 013472c0faf7eb942905f88a0773e5aa 411 SUPERFAMILY SSF52540 159 373 4.13E-28 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02390 013472c0faf7eb942905f88a0773e5aa 411 Gene3D G3DSA:3.40.50.300 159 373 1.3E-29 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02390 013472c0faf7eb942905f88a0773e5aa 411 Pfam PF13614 AAA domain 160 304 3.4E-11 T 09-03-2017 IPR025669 AAA domain UA74_RS16850 45c13c4e23e20f8d4346ecb0b3e2e6a4 314 SUPERFAMILY SSF53474 25 288 5.77E-21 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16850 45c13c4e23e20f8d4346ecb0b3e2e6a4 314 Gene3D G3DSA:3.40.50.1820 241 292 8.4E-26 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16850 45c13c4e23e20f8d4346ecb0b3e2e6a4 314 Gene3D G3DSA:3.40.50.1820 37 205 8.4E-26 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16805 4e9b6b7c15d0694b416cca3666fe1f91 252 Pfam PF14436 Bacterial EndoU nuclease 103 199 1.8E-7 T 09-03-2017 IPR029501 Bacterial EndoU nuclease UA74_RS24275 6169445075a2d2aa057df23883c8fb7a 441 SUPERFAMILY SSF53850 43 423 1.58E-60 T 09-03-2017 UA74_RS24275 6169445075a2d2aa057df23883c8fb7a 441 Gene3D G3DSA:3.40.190.10 44 164 6.3E-17 T 09-03-2017 UA74_RS24275 6169445075a2d2aa057df23883c8fb7a 441 Pfam PF13416 Bacterial extracellular solute-binding protein 57 334 2.6E-27 T 09-03-2017 UA74_RS24275 6169445075a2d2aa057df23883c8fb7a 441 Gene3D G3DSA:3.40.190.10 165 349 1.4E-38 T 09-03-2017 UA74_RS02665 2f82c0aa25f592273c15321ee1a5a055 351 SUPERFAMILY SSF47090 108 167 9.22E-11 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS02665 2f82c0aa25f592273c15321ee1a5a055 351 Pfam PF01471 Putative peptidoglycan binding domain 120 166 2.2E-10 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS02665 2f82c0aa25f592273c15321ee1a5a055 351 Gene3D G3DSA:1.10.101.10 118 167 2.5E-9 T 09-03-2017 IPR002477 Peptidoglycan binding-like UA74_RS01690 7a070705d11cdf483c8a92b2a1ac9e9e 510 Pfam PF01580 FtsK/SpoIIIE family 237 424 3.2E-15 T 09-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_RS01690 7a070705d11cdf483c8a92b2a1ac9e9e 510 Gene3D G3DSA:3.40.50.300 228 468 1.0E-14 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01690 7a070705d11cdf483c8a92b2a1ac9e9e 510 SUPERFAMILY SSF52540 212 476 1.03E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18735 df8b36426d9ae0b0ebbdfb1fbe73d396 765 SUPERFAMILY SSF50952 85 479 9.55E-12 T 09-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_RS18735 df8b36426d9ae0b0ebbdfb1fbe73d396 765 Gene3D G3DSA:2.120.10.30 80 479 1.3E-56 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS18735 df8b36426d9ae0b0ebbdfb1fbe73d396 765 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 579 756 1.2E-7 T 09-03-2017 UA74_RS18735 df8b36426d9ae0b0ebbdfb1fbe73d396 765 Pfam PF07995 Glucose / Sorbosone dehydrogenase 80 447 1.3E-24 T 09-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 UA74_RS18735 df8b36426d9ae0b0ebbdfb1fbe73d396 765 SUPERFAMILY SSF49899 491 761 1.11E-14 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS18735 df8b36426d9ae0b0ebbdfb1fbe73d396 765 Gene3D G3DSA:2.60.120.200 576 761 2.1E-9 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS15185 b9fcd9681854fb658948630e005b6753 314 Gene3D G3DSA:1.20.120.520 157 308 4.3E-31 T 09-03-2017 UA74_RS15185 b9fcd9681854fb658948630e005b6753 314 SUPERFAMILY SSF50475 36 146 6.54E-5 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS15185 b9fcd9681854fb658948630e005b6753 314 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 143 1.5E-33 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS15185 b9fcd9681854fb658948630e005b6753 314 Gene3D G3DSA:2.30.110.10 34 112 6.3E-7 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS15185 b9fcd9681854fb658948630e005b6753 314 Pfam PF04075 Domain of unknown function (DUF385) 22 143 1.3E-44 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS15185 b9fcd9681854fb658948630e005b6753 314 Pfam PF01814 Hemerythrin HHE cation binding domain 165 306 2.6E-15 T 09-03-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 UA74_RS17540 1f2afa04fcee6708bea96cbef66bfc67 248 Pfam PF08713 DNA alkylation repair enzyme 12 227 6.1E-61 T 09-03-2017 IPR014825 DNA alkylation repair enzyme UA74_RS17540 1f2afa04fcee6708bea96cbef66bfc67 248 SUPERFAMILY SSF48371 15 228 2.7E-41 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 UA74_RS17540 1f2afa04fcee6708bea96cbef66bfc67 248 Gene3D G3DSA:1.25.40.290 136 230 1.1E-20 T 09-03-2017 UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 Pfam PF03023 MviN-like protein 82 525 2.6E-89 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 55 570 2.0E-78 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 PRINTS PR01806 Virulence factor MviN signature 86 105 6.0E-23 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 PRINTS PR01806 Virulence factor MviN signature 319 345 6.0E-23 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 PRINTS PR01806 Virulence factor MviN signature 184 208 6.0E-23 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 PRINTS PR01806 Virulence factor MviN signature 416 435 6.0E-23 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 PRINTS PR01806 Virulence factor MviN signature 105 121 6.0E-23 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS30380 a854facbb6ed94c5b79c4dea4478463f 582 PRINTS PR01806 Virulence factor MviN signature 208 229 6.0E-23 T 09-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_RS19555 ee5e315718a0dfa5c2453410b2f8db33 267 Pfam PF01061 ABC-2 type transporter 12 220 8.6E-31 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS19555 ee5e315718a0dfa5c2453410b2f8db33 267 PIRSF PIRSF006648 1 267 4.0E-74 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS30050 d4fc4ccb248687dfeba740ac50ad0af7 553 Pfam PF03806 AbgT putative transporter family 286 550 8.9E-84 T 09-03-2017 IPR004697 p-aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 UA74_RS30050 d4fc4ccb248687dfeba740ac50ad0af7 553 Pfam PF03806 AbgT putative transporter family 18 247 1.1E-60 T 09-03-2017 IPR004697 p-aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 UA74_RS02540 3341495bbe02b539e42be4aa58cd3eb4 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 120 3.7E-29 T 09-03-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02540 3341495bbe02b539e42be4aa58cd3eb4 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 121 17.12 T 09-03-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 UA74_RS19645 679ee639168c57fd9e7f3826f2fe98d0 267 SUPERFAMILY SSF46785 9 82 2.69E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19645 679ee639168c57fd9e7f3826f2fe98d0 267 SMART SM00346 8 98 8.0E-18 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS19645 679ee639168c57fd9e7f3826f2fe98d0 267 Pfam PF01614 Bacterial transcriptional regulator 132 249 2.9E-30 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS19645 679ee639168c57fd9e7f3826f2fe98d0 267 Gene3D G3DSA:1.10.10.10 3 76 6.4E-22 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19645 679ee639168c57fd9e7f3826f2fe98d0 267 Gene3D G3DSA:3.30.450.40 82 256 3.1E-48 T 09-03-2017 IPR029016 GAF domain-like UA74_RS19645 679ee639168c57fd9e7f3826f2fe98d0 267 Pfam PF09339 IclR helix-turn-helix domain 10 60 2.0E-15 T 09-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_RS19645 679ee639168c57fd9e7f3826f2fe98d0 267 SUPERFAMILY SSF55781 66 254 2.49E-41 T 09-03-2017 IPR029016 GAF domain-like UA74_RS13710 c74ba22b36e925ee8175c64f9e3daefa 245 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 8 233 5.8E-62 T 09-03-2017 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 UA74_RS13710 c74ba22b36e925ee8175c64f9e3daefa 245 SUPERFAMILY SSF56784 8 234 5.79E-52 T 09-03-2017 IPR023214 HAD-like domain UA74_RS13710 c74ba22b36e925ee8175c64f9e3daefa 245 Gene3D G3DSA:3.40.50.1000 8 234 9.9E-22 T 09-03-2017 IPR023214 HAD-like domain UA74_RS13710 c74ba22b36e925ee8175c64f9e3daefa 245 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 6 234 37.295 T 09-03-2017 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 UA74_RS09210 544ebc8b2a6d487320712cde1d497b02 223 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 140 219 8.9E-19 T 09-03-2017 UA74_RS09210 544ebc8b2a6d487320712cde1d497b02 223 SUPERFAMILY SSF55166 66 220 7.46E-24 T 09-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 1.2E-9 T 09-03-2017 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 1.2E-9 T 09-03-2017 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 1.2E-9 T 09-03-2017 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 SUPERFAMILY SSF51905 296 388 1.6E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 SUPERFAMILY SSF51905 5 190 1.6E-46 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 Pfam PF04820 Tryptophan halogenase 103 405 1.5E-56 T 09-03-2017 IPR006905 Tryptophan halogenase UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 Pfam PF04820 Tryptophan halogenase 10 97 4.1E-22 T 09-03-2017 IPR006905 Tryptophan halogenase UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 Gene3D G3DSA:3.50.50.60 106 189 1.7E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 Gene3D G3DSA:3.50.50.60 5 73 1.7E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17640 92b700ff4adccfb001aae52dfac53b19 505 Gene3D G3DSA:3.50.50.60 291 335 1.7E-43 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03415 1a351aedd88322aeff9444df87cc4a88 537 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 115 200 6.9E-8 T 09-03-2017 UA74_RS03415 1a351aedd88322aeff9444df87cc4a88 537 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 345 536 4.7E-20 T 09-03-2017 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 UA74_RS19155 cf0afeb165139dbc67eac12ecf3adb6f 130 Pfam PF06304 Protein of unknown function (DUF1048) 22 122 8.6E-27 T 09-03-2017 IPR008316 Uncharacterised conserved protein UCP029876 UA74_RS19155 cf0afeb165139dbc67eac12ecf3adb6f 130 Gene3D G3DSA:1.10.1900.10 27 111 1.5E-29 T 09-03-2017 IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein GO:0003723 UA74_RS19155 cf0afeb165139dbc67eac12ecf3adb6f 130 SUPERFAMILY SSF158560 15 122 9.16E-27 T 09-03-2017 UA74_RS23220 1528338097988523deec1b12e450ed25 439 Gene3D G3DSA:2.120.10.30 65 326 4.1E-55 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS23220 1528338097988523deec1b12e450ed25 439 Gene3D G3DSA:2.120.10.30 7 64 2.4E-6 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS23220 1528338097988523deec1b12e450ed25 439 SUPERFAMILY SSF101898 19 269 1.33E-32 T 09-03-2017 UA74_RS23220 1528338097988523deec1b12e450ed25 439 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 150 324 2.5E-10 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_RS23220 1528338097988523deec1b12e450ed25 439 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 24 120 3.3E-6 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_RS30270 6a7fe7aa9326637692a70fdc5f931898 383 Pfam PF01594 Domain of unknown function DUF20 3 328 5.2E-64 T 09-03-2017 IPR002549 Transmembrane protein TqsA-like UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 SUPERFAMILY SSF54814 187 302 1.09E-34 T 09-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 285 2.8E-67 T 09-03-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 171 3.5E-17 T 09-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 Gene3D G3DSA:3.30.300.20 192 298 2.9E-36 T 09-03-2017 IPR015946 K homology domain-like, alpha/beta UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 Gene3D G3DSA:3.40.50.300 4 175 7.0E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 Pfam PF01926 50S ribosome-binding GTPase 14 129 1.8E-19 T 09-03-2017 IPR006073 GTP binding domain GO:0005525 UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 SUPERFAMILY SSF52540 14 218 5.08E-39 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 Pfam PF07650 KH domain 212 291 1.9E-17 T 09-03-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_RS24575 ce2e0704d15e470a0932ee083ebdac59 302 Hamap MF_00367 GTPase Era [era]. 8 302 34.246 T 09-03-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 UA74_RS10740 cf4e1a2b1d9e591f11558b85fb9268ab 669 Pfam PF01757 Acyltransferase family 11 342 1.5E-20 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS22400 b0e5fe0c14a52bb73822930cce26a197 417 Gene3D G3DSA:3.40.50.10540 318 410 5.4E-110 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS22400 b0e5fe0c14a52bb73822930cce26a197 417 Gene3D G3DSA:3.40.50.10540 16 229 5.4E-110 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS22400 b0e5fe0c14a52bb73822930cce26a197 417 Gene3D G3DSA:3.30.1540.10 235 317 1.7E-22 T 09-03-2017 UA74_RS22400 b0e5fe0c14a52bb73822930cce26a197 417 Pfam PF02515 CoA-transferase family III 19 385 1.4E-120 T 09-03-2017 IPR003673 CoA-transferase family III GO:0003824 UA74_RS22400 b0e5fe0c14a52bb73822930cce26a197 417 SUPERFAMILY SSF89796 16 410 3.27E-129 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS24145 56de6f63aafba13cbef6d3020f630c3c 139 Gene3D G3DSA:1.10.10.10 26 133 5.9E-45 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24145 56de6f63aafba13cbef6d3020f630c3c 139 SUPERFAMILY SSF46785 27 133 1.84E-34 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24145 56de6f63aafba13cbef6d3020f630c3c 139 Pfam PF01638 HxlR-like helix-turn-helix 39 125 1.9E-28 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS29960 cccf774c2adfa9db9f4339d84b2df9e3 328 SUPERFAMILY SSF160240 233 305 1.06E-5 T 09-03-2017 UA74_RS29960 cccf774c2adfa9db9f4339d84b2df9e3 328 SUPERFAMILY SSF161111 16 229 1.57E-37 T 09-03-2017 UA74_RS29960 cccf774c2adfa9db9f4339d84b2df9e3 328 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 16 308 2.0E-50 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_RS29960 cccf774c2adfa9db9f4339d84b2df9e3 328 Pfam PF01545 Cation efflux family 18 227 1.3E-34 T 09-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_RS29960 cccf774c2adfa9db9f4339d84b2df9e3 328 Gene3D G3DSA:1.20.1510.10 16 227 2.1E-32 T 09-03-2017 IPR027469 Cation efflux protein transmembrane domain UA74_RS29960 cccf774c2adfa9db9f4339d84b2df9e3 328 Gene3D G3DSA:3.30.70.1350 231 307 3.7E-7 T 09-03-2017 IPR027470 Cation efflux protein, cytoplasmic domain UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 Pfam PF07690 Major Facilitator Superfamily 24 411 4.4E-42 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 Gene3D G3DSA:1.20.1250.20 472 497 1.5E-15 T 09-03-2017 UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 Gene3D G3DSA:1.20.1250.20 267 422 1.5E-15 T 09-03-2017 UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 SUPERFAMILY SSF103473 471 496 2.09E-55 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 SUPERFAMILY SSF103473 8 200 2.09E-55 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 SUPERFAMILY SSF103473 250 421 2.09E-55 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 29 45 1.1E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 331 354 1.1E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 59 78 1.1E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 142 164 1.1E-8 T 09-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_RS19565 ba5d5165af0d2623fa89d9311d65d393 517 Gene3D G3DSA:1.20.1250.20 25 197 1.4E-25 T 09-03-2017 UA74_RS27985 4640446aad3f54c8f32ef6763e46e7db 372 Pfam PF00892 EamA-like transporter family 141 276 7.4E-18 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS27985 4640446aad3f54c8f32ef6763e46e7db 372 Pfam PF00892 EamA-like transporter family 3 130 2.2E-16 T 09-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_RS27985 4640446aad3f54c8f32ef6763e46e7db 372 SUPERFAMILY SSF103481 30 133 2.68E-10 T 09-03-2017 UA74_RS27985 4640446aad3f54c8f32ef6763e46e7db 372 SUPERFAMILY SSF103481 186 281 9.42E-14 T 09-03-2017 UA74_RS02695 0502a68dd222f204f89ccfa612421c46 301 Gene3D G3DSA:1.10.510.10 73 253 1.3E-41 T 09-03-2017 UA74_RS02695 0502a68dd222f204f89ccfa612421c46 301 SMART SM00220 7 266 1.3E-45 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS02695 0502a68dd222f204f89ccfa612421c46 301 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS02695 0502a68dd222f204f89ccfa612421c46 301 Pfam PF00069 Protein kinase domain 13 255 7.3E-40 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS02695 0502a68dd222f204f89ccfa612421c46 301 Gene3D G3DSA:3.30.200.20 3 72 7.4E-17 T 09-03-2017 UA74_RS02695 0502a68dd222f204f89ccfa612421c46 301 SUPERFAMILY SSF56112 5 260 1.75E-65 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS02695 0502a68dd222f204f89ccfa612421c46 301 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS10820 843a4b1fbceb493509f5819daaae999c 246 SUPERFAMILY SSF102215 4 239 5.49E-51 T 09-03-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 UA74_RS10820 843a4b1fbceb493509f5819daaae999c 246 Gene3D G3DSA:3.40.50.10310 4 239 3.2E-61 T 09-03-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 UA74_RS10820 843a4b1fbceb493509f5819daaae999c 246 Pfam PF02633 Creatinine amidohydrolase 20 237 6.4E-52 T 09-03-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 UA74_RS19625 f8911e3e493eb34dc9bf7b6912fc737e 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 267 1.6E-15 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19625 f8911e3e493eb34dc9bf7b6912fc737e 275 Gene3D G3DSA:1.10.3720.10 3 261 4.0E-59 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19625 f8911e3e493eb34dc9bf7b6912fc737e 275 SUPERFAMILY SSF161098 4 275 1.59E-65 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS14195 9f3e973fa43df858348ae56bc28b2708 333 Pfam PF01758 Sodium Bile acid symporter family 47 218 1.6E-11 T 09-03-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UA74_RS18775 1dc7bee925681f3f3306218ac955382e 334 Pfam PF00494 Squalene/phytoene synthase 25 273 4.9E-34 T 09-03-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 UA74_RS18775 1dc7bee925681f3f3306218ac955382e 334 Gene3D G3DSA:1.10.600.10 7 281 1.5E-37 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS18775 1dc7bee925681f3f3306218ac955382e 334 SUPERFAMILY SSF48576 11 285 1.29E-41 T 09-03-2017 IPR008949 Isoprenoid synthase domain UA74_RS23165 c31a243f48078eb8e9cf110603d76384 400 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 3 350 4.6E-87 T 09-03-2017 IPR010148 CRISPR-associated protein, CT1975 UA74_RS23165 c31a243f48078eb8e9cf110603d76384 400 Pfam PF09344 CT1975-like protein 3 376 1.1E-106 T 09-03-2017 IPR010148 CRISPR-associated protein, CT1975 UA74_RS27685 0b1ff9627c3fe06c41b4d2b7929fc3e3 141 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 123 1.5E-14 T 09-03-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_RS27685 0b1ff9627c3fe06c41b4d2b7929fc3e3 141 Gene3D G3DSA:1.20.950.10 5 139 5.1E-40 T 09-03-2017 UA74_RS27685 0b1ff9627c3fe06c41b4d2b7929fc3e3 141 SUPERFAMILY SSF81343 9 137 5.45E-32 T 09-03-2017 UA74_RS22130 deb99a33af06e160efc2ecd52f798382 122 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 57 108 2.5E-6 T 09-03-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 UA74_RS22130 deb99a33af06e160efc2ecd52f798382 122 SUPERFAMILY SSF51197 31 110 1.79E-15 T 09-03-2017 UA74_RS22130 deb99a33af06e160efc2ecd52f798382 122 Gene3D G3DSA:3.60.130.10 17 109 1.7E-15 T 09-03-2017 UA74_RS20660 6523ad5bab520d29537a888be7ce27d6 360 SUPERFAMILY SSF141571 194 245 2.35E-5 T 09-03-2017 UA74_RS20660 6523ad5bab520d29537a888be7ce27d6 360 Pfam PF00805 Pentapeptide repeats (8 copies) 196 235 1.5E-4 T 09-03-2017 IPR001646 Pentapeptide repeat UA74_RS19495 34bcb95047885fd1a4824cd5c5a9074a 334 Pfam PF01032 FecCD transport family 19 328 1.2E-90 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS19495 34bcb95047885fd1a4824cd5c5a9074a 334 SUPERFAMILY SSF81345 7 329 2.09E-77 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS19495 34bcb95047885fd1a4824cd5c5a9074a 334 Gene3D G3DSA:1.10.3470.10 8 330 4.8E-99 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS19460 ffe2ca3ad6aa65cc72f19b0279ff4063 110 SUPERFAMILY SSF103481 11 105 1.28E-19 T 09-03-2017 UA74_RS19460 ffe2ca3ad6aa65cc72f19b0279ff4063 110 Pfam PF00893 Small Multidrug Resistance protein 7 98 6.3E-25 T 09-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 UA74_RS23140 b706a9c293d42867ebb21d6b28837e8a 411 SUPERFAMILY SSF53756 147 318 5.02E-9 T 09-03-2017 UA74_RS12310 7e6d0d45c9a898b48051021b8b430824 105 Gene3D G3DSA:1.10.8.50 50 104 2.4E-10 T 09-03-2017 UA74_RS12310 7e6d0d45c9a898b48051021b8b430824 105 SUPERFAMILY SSF46946 54 103 5.1E-6 T 09-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_RS12980 8e037ff30e0f42bb553e35684c390896 65 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 65 16.883 T 09-03-2017 IPR008515 Ubiquitin-like, Pup UA74_RS12980 8e037ff30e0f42bb553e35684c390896 65 Pfam PF05639 Pup-like protein 3 65 4.5E-22 T 09-03-2017 IPR008515 Ubiquitin-like, Pup UA74_RS12980 8e037ff30e0f42bb553e35684c390896 65 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 34 65 1.6E-20 T 09-03-2017 IPR008515 Ubiquitin-like, Pup UA74_RS23505 d956dacb220fe93d810d81de2e30792c 290 SUPERFAMILY SSF53300 13 185 8.38E-10 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS23505 d956dacb220fe93d810d81de2e30792c 290 Gene3D G3DSA:3.40.50.410 12 184 1.1E-4 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS11665 1dd6b4169a1e51d05a634f3172efe4ce 479 Gene3D G3DSA:3.40.605.10 8 263 2.3E-68 T 09-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 UA74_RS11665 1dd6b4169a1e51d05a634f3172efe4ce 479 Pfam PF00171 Aldehyde dehydrogenase family 18 472 6.4E-130 T 09-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 UA74_RS11665 1dd6b4169a1e51d05a634f3172efe4ce 479 Gene3D G3DSA:3.40.309.10 264 445 1.0E-56 T 09-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 UA74_RS11665 1dd6b4169a1e51d05a634f3172efe4ce 479 SUPERFAMILY SSF53720 7 475 1.7E-128 T 09-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 UA74_RS11940 512a51c978c4dfd7d0b646d3c96c5cc0 103 Pfam PF05336 Domain of unknown function (DUF718) 4 91 7.3E-16 T 09-03-2017 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UA74_RS11940 512a51c978c4dfd7d0b646d3c96c5cc0 103 SUPERFAMILY SSF54909 1 102 2.32E-21 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS03625 1c2bbb19b460596d0fd066d6d72749bf 38 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.0E-13 T 09-03-2017 IPR019933 DivIVA domain UA74_RS18345 97110293aba631c7b4ae8cc7986cf8e4 158 Pfam PF00106 short chain dehydrogenase 7 93 1.0E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS18345 97110293aba631c7b4ae8cc7986cf8e4 158 Gene3D G3DSA:3.40.50.720 3 98 3.7E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18345 97110293aba631c7b4ae8cc7986cf8e4 158 SUPERFAMILY SSF51735 2 98 5.33E-19 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS04700 c81b6095a9bbd572a6232b01a985a84a 359 PIRSF PIRSF012608 1 359 3.2E-73 T 09-03-2017 IPR011200 Uncharacterised conserved protein UCP012608 UA74_RS04700 c81b6095a9bbd572a6232b01a985a84a 359 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 4 357 6.3E-93 T 09-03-2017 IPR011200 Uncharacterised conserved protein UCP012608 UA74_RS21475 6a5e5a4c54187244a354effc13e42952 187 SUPERFAMILY SSF46785 96 163 1.06E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21475 6a5e5a4c54187244a354effc13e42952 187 Gene3D G3DSA:1.10.10.10 100 163 1.9E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS21475 6a5e5a4c54187244a354effc13e42952 187 Pfam PF12840 Helix-turn-helix domain 103 160 1.0E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS19390 6f342ea4fb0b25aeef6c2faeedad6a2f 306 Pfam PF09362 Domain of unknown function (DUF1996) 54 261 6.6E-49 T 09-03-2017 IPR018535 Domain of unknown function DUF1996 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 Gene3D G3DSA:1.10.630.10 13 409 1.4E-113 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 SUPERFAMILY SSF48264 17 408 1.1E-88 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00385 P450 superfamily signature 279 290 1.4E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00385 P450 superfamily signature 347 356 1.4E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00385 P450 superfamily signature 244 261 1.4E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00385 P450 superfamily signature 356 367 1.4E-5 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 160 175 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 347 356 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 297 324 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 356 367 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 197 219 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 279 290 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 143 159 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 PRINTS PR00359 B-class P450 signature 93 104 1.5E-36 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 Pfam PF00067 Cytochrome P450 278 377 9.9E-16 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 Pfam PF00067 Cytochrome P450 211 271 1.8E-6 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS20375 5b3c425e834ea477158caf48449b2a58 412 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS08075 78140ca499c243781a52d1b7928693a2 157 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.1E-51 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS08075 78140ca499c243781a52d1b7928693a2 157 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 3.0E-65 T 09-03-2017 IPR011860 Ribose 5-phosphate isomerase GO:0004751 UA74_RS08075 78140ca499c243781a52d1b7928693a2 157 SUPERFAMILY SSF89623 2 151 1.19E-48 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS08075 78140ca499c243781a52d1b7928693a2 157 Gene3D G3DSA:3.40.1400.10 2 148 1.2E-51 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS08075 78140ca499c243781a52d1b7928693a2 157 Pfam PF02502 Ribose/Galactose Isomerase 3 140 4.2E-43 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS08075 78140ca499c243781a52d1b7928693a2 157 PIRSF PIRSF005384 1 149 6.4E-46 T 09-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_RS07850 ccfe90e5b85b9510a69d28626ad900d5 154 SUPERFAMILY SSF55961 2 139 5.94E-25 T 09-03-2017 UA74_RS07850 ccfe90e5b85b9510a69d28626ad900d5 154 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 128 7.2E-17 T 09-03-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain UA74_RS07850 ccfe90e5b85b9510a69d28626ad900d5 154 Gene3D G3DSA:3.30.530.20 4 132 3.2E-9 T 09-03-2017 IPR023393 START-like domain UA74_RS08250 4dc7d98a3a9eb42166a9a376d999985b 284 Pfam PF01061 ABC-2 type transporter 38 246 1.4E-19 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS08250 4dc7d98a3a9eb42166a9a376d999985b 284 PIRSF PIRSF006648 10 282 7.1E-24 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08250 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 226 245 4.6E-18 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08250 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 133 158 4.6E-18 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08250 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 170 194 4.6E-18 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08250 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 4.6E-18 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS08250 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 53 74 4.6E-18 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS15180 8e980711a5d2273e8908727c7759fd7b 303 SMART SM00530 10 83 1.0E-8 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS15180 8e980711a5d2273e8908727c7759fd7b 303 Gene3D G3DSA:1.10.260.40 3 82 1.4E-21 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS15180 8e980711a5d2273e8908727c7759fd7b 303 SUPERFAMILY SSF47413 29 82 1.42E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS15180 8e980711a5d2273e8908727c7759fd7b 303 Pfam PF13560 Helix-turn-helix domain 7 86 6.9E-18 T 09-03-2017 UA74_RS17305 3dca155f5a80c03f4f22597b340935d5 279 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 178 8.1E-13 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS17305 3dca155f5a80c03f4f22597b340935d5 279 SUPERFAMILY SSF51735 5 216 9.02E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17305 3dca155f5a80c03f4f22597b340935d5 279 Gene3D G3DSA:3.40.50.720 16 193 1.1E-14 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS09350 cef57d81d8ade1480b32c0117faaad57 443 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 413 8.8E-91 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_RS09350 cef57d81d8ade1480b32c0117faaad57 443 Pfam PF01554 MatE 244 395 9.1E-11 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_RS09350 cef57d81d8ade1480b32c0117faaad57 443 Pfam PF01554 MatE 26 186 8.2E-27 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_RS09350 cef57d81d8ade1480b32c0117faaad57 443 PIRSF PIRSF006603 11 443 1.9E-50 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_RS12665 265ea6a36e490eaea0bcb12d7386fce4 394 SUPERFAMILY SSF51905 235 311 1.48E-18 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12665 265ea6a36e490eaea0bcb12d7386fce4 394 SUPERFAMILY SSF51905 1 148 1.48E-18 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12665 265ea6a36e490eaea0bcb12d7386fce4 394 TIGRFAM TIGR01790 carotene-cycl: lycopene cyclase family protein 2 373 8.8E-66 T 09-03-2017 IPR010108 Lycopene cyclase, beta/epsilon GO:0016117|GO:0016705 UA74_RS12665 265ea6a36e490eaea0bcb12d7386fce4 394 Gene3D G3DSA:3.50.50.60 1 135 7.9E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12665 265ea6a36e490eaea0bcb12d7386fce4 394 Gene3D G3DSA:3.50.50.60 214 285 7.9E-17 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS12665 265ea6a36e490eaea0bcb12d7386fce4 394 Pfam PF05834 Lycopene cyclase protein 1 349 3.0E-57 T 09-03-2017 UA74_RS29755 edf6201688b79f686c6c2dbe2bffa68e 186 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 29 117 9.4E-11 T 09-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_RS29755 edf6201688b79f686c6c2dbe2bffa68e 186 SUPERFAMILY SSF50475 23 158 2.07E-14 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS29755 edf6201688b79f686c6c2dbe2bffa68e 186 Gene3D G3DSA:2.30.110.10 16 148 2.3E-22 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS29290 256c2cf1b3d0b0b175bfdbc5cb277554 266 SUPERFAMILY SSF46894 121 221 1.47E-30 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS29290 256c2cf1b3d0b0b175bfdbc5cb277554 266 SMART SM00862 146 220 3.6E-29 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS29290 256c2cf1b3d0b0b175bfdbc5cb277554 266 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 6.6E-29 T 09-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_RS29290 256c2cf1b3d0b0b175bfdbc5cb277554 266 Gene3D G3DSA:1.10.10.10 122 222 1.2E-36 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS07690 6f6d9539b3bfccf0275b1ba2f0debb94 154 SUPERFAMILY SSF54427 8 144 5.48E-6 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS07690 6f6d9539b3bfccf0275b1ba2f0debb94 154 Gene3D G3DSA:3.10.450.50 12 143 1.4E-5 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS22380 44fa61753ca8e31a751219d457acd8a8 180 Pfam PF01220 Dehydroquinase class II 19 163 1.0E-28 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS22380 44fa61753ca8e31a751219d457acd8a8 180 SUPERFAMILY SSF52304 19 169 7.85E-30 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS22380 44fa61753ca8e31a751219d457acd8a8 180 PIRSF PIRSF001399 16 169 2.2E-28 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS22380 44fa61753ca8e31a751219d457acd8a8 180 Gene3D G3DSA:3.40.50.9100 18 167 4.1E-32 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS22380 44fa61753ca8e31a751219d457acd8a8 180 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 20 138 1.0E-16 T 09-03-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 Gene3D G3DSA:2.120.10.30 528 636 3.6E-10 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 Gene3D G3DSA:2.120.10.30 368 463 3.6E-10 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 Gene3D G3DSA:2.120.10.30 279 330 8.8E-11 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 Gene3D G3DSA:2.120.10.30 53 229 8.8E-11 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 SUPERFAMILY SSF101898 74 330 5.75E-16 T 09-03-2017 UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 Pfam PF13360 PQQ-like domain 270 462 2.1E-7 T 09-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 SUPERFAMILY SSF82171 391 467 1.37E-13 T 09-03-2017 UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 SUPERFAMILY SSF82171 554 688 1.37E-13 T 09-03-2017 UA74_RS18780 cc7a43948d567c54123c2358d92199d1 706 SUPERFAMILY SSF82171 278 336 1.37E-13 T 09-03-2017 UA74_RS07455 e5f9ea005bb5c2d977178688442e2939 314 SUPERFAMILY SSF161098 30 314 6.13E-49 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07455 e5f9ea005bb5c2d977178688442e2939 314 Gene3D G3DSA:1.10.3720.10 30 301 2.1E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07455 e5f9ea005bb5c2d977178688442e2939 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 307 4.9E-11 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS25450 6e1bdd5031f8ec4db333921ba1201e22 511 Pfam PF09660 Protein of unknown function (DUF2397) 21 507 6.8E-114 T 09-03-2017 IPR013493 Conserved hypothetical protein CHP02677 UA74_RS10115 abbdd7781ca4a9bf9c8c3c6c45eb121e 248 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 69 244 1.1E-30 T 09-03-2017 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp UA74_RS01600 78f231936d88f840d1ffa5211de035d9 307 SUPERFAMILY SSF56219 88 303 9.29E-28 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS01600 78f231936d88f840d1ffa5211de035d9 307 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 90 296 1.4E-20 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS01600 78f231936d88f840d1ffa5211de035d9 307 Gene3D G3DSA:3.60.10.10 84 303 7.2E-10 T 09-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase UA74_RS27090 7cc2b445c51f3ae7d4b9890d9caf2ead 142 Gene3D G3DSA:3.30.70.1060 1 117 5.8E-42 T 09-03-2017 UA74_RS27090 7cc2b445c51f3ae7d4b9890d9caf2ead 142 Pfam PF03795 YCII-related domain 1 114 1.3E-26 T 09-03-2017 IPR005545 YCII-related UA74_RS27090 7cc2b445c51f3ae7d4b9890d9caf2ead 142 SUPERFAMILY SSF54909 1 118 3.93E-37 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS14545 60e3726a45285877ceb40439359e623d 324 SUPERFAMILY SSF81345 3 318 3.66E-69 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS14545 60e3726a45285877ceb40439359e623d 324 Gene3D G3DSA:1.10.3470.10 2 321 3.7E-85 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS14545 60e3726a45285877ceb40439359e623d 324 Pfam PF01032 FecCD transport family 10 318 1.0E-79 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS05485 d9cdcb1ba3cbf8c1abdfbe573d1b733a 296 SUPERFAMILY SSF52540 5 220 4.39E-57 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05485 d9cdcb1ba3cbf8c1abdfbe573d1b733a 296 Gene3D G3DSA:3.40.50.300 3 220 1.4E-63 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05485 d9cdcb1ba3cbf8c1abdfbe573d1b733a 296 Pfam PF00005 ABC transporter 23 159 3.3E-29 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS05485 d9cdcb1ba3cbf8c1abdfbe573d1b733a 296 SMART SM00382 31 213 2.3E-8 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS05485 d9cdcb1ba3cbf8c1abdfbe573d1b733a 296 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS13705 7a604cd60892bb71e71099e210b2d253 225 SMART SM01007 20 209 1.8E-37 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS13705 7a604cd60892bb71e71099e210b2d253 225 SUPERFAMILY SSF53639 20 213 6.47E-37 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS13705 7a604cd60892bb71e71099e210b2d253 225 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 25 212 3.9E-49 T 09-03-2017 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 UA74_RS13705 7a604cd60892bb71e71099e210b2d253 225 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 217 70.359 T 09-03-2017 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 UA74_RS13705 7a604cd60892bb71e71099e210b2d253 225 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 22 206 7.5E-33 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS13705 7a604cd60892bb71e71099e210b2d253 225 Gene3D G3DSA:3.40.225.10 21 213 3.5E-37 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS01400 6fab7d1510611f8d89eb8234a29f0ae1 770 PIRSF PIRSF001265 19 724 9.1E-248 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 UA74_RS01400 6fab7d1510611f8d89eb8234a29f0ae1 770 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 22 716 24.094 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 UA74_RS01400 6fab7d1510611f8d89eb8234a29f0ae1 770 Pfam PF03030 Inorganic H+ pyrophosphatase 34 711 7.1E-237 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 UA74_RS01400 6fab7d1510611f8d89eb8234a29f0ae1 770 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 27 717 5.9E-206 T 09-03-2017 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 UA74_RS10905 1f5c2e38554532cf9d20a81b2e92c4d0 165 Pfam PF14081 Domain of unknown function (DUF4262) 16 138 1.2E-37 T 09-03-2017 IPR025358 Protein of unknown function DUF4262 UA74_RS14365 cda1cd8975dcbe1655d04ab77ee87511 191 SUPERFAMILY SSF46689 7 72 2.69E-15 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14365 cda1cd8975dcbe1655d04ab77ee87511 191 SUPERFAMILY SSF48498 79 186 4.45E-22 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS14365 cda1cd8975dcbe1655d04ab77ee87511 191 Gene3D G3DSA:1.10.357.10 6 187 2.0E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS14365 cda1cd8975dcbe1655d04ab77ee87511 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 58 7.9E-12 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS08710 5eee8cb335ca4ed7e6d98c635a2e5422 304 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 1 285 6.9E-71 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UA74_RS08710 5eee8cb335ca4ed7e6d98c635a2e5422 304 Gene3D G3DSA:1.10.287.890 193 276 9.8E-20 T 09-03-2017 UA74_RS08710 5eee8cb335ca4ed7e6d98c635a2e5422 304 SUPERFAMILY SSF52540 1 144 7.14E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08710 5eee8cb335ca4ed7e6d98c635a2e5422 304 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 1 295 24.891 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UA74_RS08710 5eee8cb335ca4ed7e6d98c635a2e5422 304 Gene3D G3DSA:3.40.50.300 1 165 7.4E-49 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08710 5eee8cb335ca4ed7e6d98c635a2e5422 304 Pfam PF01715 IPP transferase 33 279 1.6E-70 T 09-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UA74_RS08545 b99402d32aaae600f34da9e6a6f202d1 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 4.9E-45 T 09-03-2017 IPR025242 Protein of unknown function DUF4193 UA74_RS04025 2765d612c80cc6a51f70cbd4322edd57 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 288 54.026 T 09-03-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 UA74_RS04025 2765d612c80cc6a51f70cbd4322edd57 293 SUPERFAMILY SSF102588 4 287 1.96E-75 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS04025 2765d612c80cc6a51f70cbd4322edd57 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 153 6.8E-27 T 09-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_RS04025 2765d612c80cc6a51f70cbd4322edd57 293 Gene3D G3DSA:3.40.50.10320 2 290 2.9E-91 T 09-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 UA74_RS04025 2765d612c80cc6a51f70cbd4322edd57 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 287 8.1E-155 T 09-03-2017 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 UA74_RS16275 f3361f8a564210b66c49eb1e5170a2de 153 Gene3D G3DSA:1.10.10.10 7 107 1.2E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16275 f3361f8a564210b66c49eb1e5170a2de 153 SUPERFAMILY SSF46785 11 105 1.57E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02235 ecc43f37ac20d93d3c0d90412ea17e6d 308 Gene3D G3DSA:3.20.20.220 36 302 1.0E-70 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like UA74_RS02235 ecc43f37ac20d93d3c0d90412ea17e6d 308 PIRSF PIRSF000196 1 308 1.6E-106 T 09-03-2017 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 UA74_RS02235 ecc43f37ac20d93d3c0d90412ea17e6d 308 Pfam PF01619 Proline dehydrogenase 46 296 6.8E-34 T 09-03-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 UA74_RS02235 ecc43f37ac20d93d3c0d90412ea17e6d 308 SUPERFAMILY SSF51730 37 303 9.02E-69 T 09-03-2017 IPR029041 FAD-linked oxidoreductase-like UA74_RS15585 33dd6b5bf59dbbdea94a50831b1c274e 253 Pfam PF01061 ABC-2 type transporter 2 207 5.0E-24 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS15585 33dd6b5bf59dbbdea94a50831b1c274e 253 PIRSF PIRSF006648 1 253 6.8E-65 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS19335 55d46d38dc8f95924274813ce3aa1345 402 Gene3D G3DSA:1.20.1250.20 14 188 2.1E-12 T 09-03-2017 UA74_RS19335 55d46d38dc8f95924274813ce3aa1345 402 Gene3D G3DSA:1.20.1250.20 218 394 2.8E-10 T 09-03-2017 UA74_RS19335 55d46d38dc8f95924274813ce3aa1345 402 SUPERFAMILY SSF103473 13 398 1.31E-31 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19335 55d46d38dc8f95924274813ce3aa1345 402 Pfam PF05977 Transmembrane secretion effector 6 397 1.8E-20 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS03340 f33cdff20b3f7f5c23af92c501cbec92 190 SUPERFAMILY SSF109854 79 182 1.67E-15 T 09-03-2017 UA74_RS03340 f33cdff20b3f7f5c23af92c501cbec92 190 SUPERFAMILY SSF109854 10 44 1.67E-15 T 09-03-2017 UA74_RS03340 f33cdff20b3f7f5c23af92c501cbec92 190 Pfam PF12867 DinB superfamily 13 174 3.8E-18 T 09-03-2017 IPR024775 DinB-like domain UA74_RS03340 f33cdff20b3f7f5c23af92c501cbec92 190 Gene3D G3DSA:1.20.120.450 112 181 8.7E-4 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS21465 c9b1eba5ba64beb2db0e53653bf5f166 130 SMART SM00507 12 66 7.9E-5 T 09-03-2017 IPR003615 HNH nuclease UA74_RS21465 c9b1eba5ba64beb2db0e53653bf5f166 130 Pfam PF14279 HNH endonuclease 25 70 1.8E-9 T 09-03-2017 IPR029471 HNH endonuclease 5 UA74_RS13280 5af13a7be2987c61d33ef8a1f3fae71c 314 Pfam PF01758 Sodium Bile acid symporter family 45 222 1.7E-42 T 09-03-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UA74_RS28825 8d84bcec4211fee72285e583b0af151a 293 SMART SM00046 6 134 0.0014 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_RS28825 8d84bcec4211fee72285e583b0af151a 293 SUPERFAMILY SSF111331 6 292 1.5E-37 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain UA74_RS28825 8d84bcec4211fee72285e583b0af151a 293 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 126 2.2E-15 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_RS26805 89c51268fd85ca3806838739513ee402 104 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 26 104 19.382 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS26805 89c51268fd85ca3806838739513ee402 104 Pfam PF02467 Transcription factor WhiB 36 99 2.3E-27 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS29100 1f6f9125d0709c5c1a590526d023d26d 313 Gene3D G3DSA:3.40.50.720 8 291 4.5E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29100 1f6f9125d0709c5c1a590526d023d26d 313 SUPERFAMILY SSF51735 8 298 4.25E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS29100 1f6f9125d0709c5c1a590526d023d26d 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 216 8.0E-13 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS04550 c1d814502b27d40a3933eb262dff7873 281 SUPERFAMILY SSF47413 12 70 6.57E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS04550 c1d814502b27d40a3933eb262dff7873 281 Pfam PF13560 Helix-turn-helix domain 13 73 5.1E-10 T 09-03-2017 UA74_RS04550 c1d814502b27d40a3933eb262dff7873 281 Gene3D G3DSA:1.10.260.40 6 69 1.8E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS04490 590e19388b7b28c79167fc473cf7cb02 268 Gene3D G3DSA:3.40.50.450 65 265 6.2E-63 T 09-03-2017 UA74_RS04490 590e19388b7b28c79167fc473cf7cb02 268 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 84 257 3.7E-42 T 09-03-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG UA74_RS04490 590e19388b7b28c79167fc473cf7cb02 268 Pfam PF03641 Possible lysine decarboxylase 127 255 5.9E-31 T 09-03-2017 IPR031100 LOG family UA74_RS04490 590e19388b7b28c79167fc473cf7cb02 268 SUPERFAMILY SSF102405 55 256 5.65E-61 T 09-03-2017 UA74_RS10710 457922dfd03e74e4b23f4a3576c2198d 131 SUPERFAMILY SSF54593 6 123 2.28E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS10710 457922dfd03e74e4b23f4a3576c2198d 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 123 9.6E-11 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS10710 457922dfd03e74e4b23f4a3576c2198d 131 Gene3D G3DSA:3.10.180.10 8 128 8.0E-30 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS28085 657366548752c35dbff72c602cec1e12 115 SMART SM00422 20 89 1.6E-4 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS28085 657366548752c35dbff72c602cec1e12 115 Gene3D G3DSA:1.10.1660.10 20 86 2.3E-12 T 09-03-2017 UA74_RS28085 657366548752c35dbff72c602cec1e12 115 Pfam PF13411 MerR HTH family regulatory protein 21 85 3.7E-14 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS28085 657366548752c35dbff72c602cec1e12 115 SUPERFAMILY SSF46955 20 87 1.1E-12 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS22815 02500818b7c86e397f461bfabd97bc37 213 SUPERFAMILY SSF51569 9 210 2.75E-51 T 09-03-2017 UA74_RS22815 02500818b7c86e397f461bfabd97bc37 213 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 209 6.5E-50 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS22815 02500818b7c86e397f461bfabd97bc37 213 Pfam PF01081 KDPG and KHG aldolase 11 201 8.0E-41 T 09-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_RS22815 02500818b7c86e397f461bfabd97bc37 213 Gene3D G3DSA:3.20.20.70 7 212 3.9E-60 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS26870 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 SUPERFAMILY SSF53448 9 132 6.38E-40 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS26870 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 SUPERFAMILY SSF53448 274 358 6.38E-40 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS26870 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 Pfam PF00535 Glycosyl transferase family 2 10 134 7.0E-19 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS26870 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 Gene3D G3DSA:3.90.550.10 7 130 1.0E-40 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS26870 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 Gene3D G3DSA:3.90.550.10 255 359 1.0E-40 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS11095 2ab967bf889bf784a80b5c14d280e99c 153 Pfam PF08592 Domain of unknown function (DUF1772) 18 146 3.7E-14 T 09-03-2017 IPR013901 Protein of unknown function DUF1772 UA74_RS27615 db14d19e5b19ae37d16c69611bc0d408 329 SUPERFAMILY SSF52540 8 220 2.05E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27615 db14d19e5b19ae37d16c69611bc0d408 329 Pfam PF00005 ABC transporter 21 157 2.5E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS27615 db14d19e5b19ae37d16c69611bc0d408 329 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS27615 db14d19e5b19ae37d16c69611bc0d408 329 Gene3D G3DSA:3.40.50.300 9 219 8.0E-59 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27615 db14d19e5b19ae37d16c69611bc0d408 329 SMART SM00382 30 206 5.1E-13 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10830 30a6c6cafe0ea910c8788dd3321dd26f 181 SUPERFAMILY SSF54197 17 169 1.55E-40 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS10830 30a6c6cafe0ea910c8788dd3321dd26f 181 Pfam PF01230 HIT domain 53 145 6.5E-13 T 09-03-2017 IPR001310 Histidine triad (HIT) protein UA74_RS10830 30a6c6cafe0ea910c8788dd3321dd26f 181 Gene3D G3DSA:3.30.428.10 38 179 2.2E-40 T 09-03-2017 IPR011146 HIT-like domain GO:0003824 UA74_RS24400 0f890b0eec672fae4361df998eedeb0c 349 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 12 130 2.0E-14 T 09-03-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 UA74_RS24400 0f890b0eec672fae4361df998eedeb0c 349 SUPERFAMILY SSF51735 9 154 1.62E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS24400 0f890b0eec672fae4361df998eedeb0c 349 Gene3D G3DSA:3.40.50.720 10 153 7.8E-20 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14345 feb12c35303c160344162111e139c347 453 Pfam PF02447 GntP family permease 6 445 2.1E-80 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_RS22860 66e0b28d2e289f9e156824ee183da4b3 316 SUPERFAMILY SSF51430 1 308 5.63E-96 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS22860 66e0b28d2e289f9e156824ee183da4b3 316 Pfam PF00248 Aldo/keto reductase family 11 308 1.4E-72 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS22860 66e0b28d2e289f9e156824ee183da4b3 316 Gene3D G3DSA:3.20.20.100 1 310 5.7E-108 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 379 387 8.7E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 400 411 8.7E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 8.7E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 421 438 8.7E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 445 457 8.7E-21 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 TIGRFAM TIGR03356 BGL: beta-galactosidase 21 466 3.2E-180 T 09-03-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 SUPERFAMILY SSF51445 20 477 7.69E-162 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 Gene3D G3DSA:3.20.20.80 20 478 6.7E-162 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 25 39 - T 09-03-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UA74_RS21130 259eba7d3d8ad8ebce1112648a713622 485 Pfam PF00232 Glycosyl hydrolase family 1 18 475 8.4E-163 T 09-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_RS10700 84092ab130fa0f0657ad5c0062bc3eed 144 Gene3D G3DSA:3.10.129.10 6 136 5.7E-45 T 09-03-2017 IPR029069 HotDog domain UA74_RS10700 84092ab130fa0f0657ad5c0062bc3eed 144 Pfam PF03061 Thioesterase superfamily 48 124 2.2E-15 T 09-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 UA74_RS10700 84092ab130fa0f0657ad5c0062bc3eed 144 SUPERFAMILY SSF54637 19 137 2.89E-28 T 09-03-2017 IPR029069 HotDog domain UA74_RS10700 84092ab130fa0f0657ad5c0062bc3eed 144 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 132 6.2E-30 T 09-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 UA74_RS11315 320711b993c7463b3fa06c77a78abc89 295 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 10 234 5.0E-92 T 09-03-2017 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c UA74_RS11315 320711b993c7463b3fa06c77a78abc89 295 SUPERFAMILY SSF51679 1 294 6.33E-54 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS11315 320711b993c7463b3fa06c77a78abc89 295 Gene3D G3DSA:3.20.20.30 1 294 3.4E-61 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS11315 320711b993c7463b3fa06c77a78abc89 295 Pfam PF00296 Luciferase-like monooxygenase 1 235 1.1E-39 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS14245 b04f2f231f3a7eaa1addcf16b2b2f626 213 Gene3D G3DSA:3.40.50.1000 1 8 1.7E-32 T 09-03-2017 IPR023214 HAD-like domain UA74_RS14245 b04f2f231f3a7eaa1addcf16b2b2f626 213 Gene3D G3DSA:3.40.50.1000 83 181 1.7E-32 T 09-03-2017 IPR023214 HAD-like domain UA74_RS14245 b04f2f231f3a7eaa1addcf16b2b2f626 213 SUPERFAMILY SSF56784 1 181 2.8E-41 T 09-03-2017 IPR023214 HAD-like domain UA74_RS14245 b04f2f231f3a7eaa1addcf16b2b2f626 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 178 3.1E-22 T 09-03-2017 IPR023214 HAD-like domain UA74_RS14245 b04f2f231f3a7eaa1addcf16b2b2f626 213 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 75 178 2.8E-13 T 09-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 UA74_RS09265 17c2705e4afea037886e5bde757ff0e7 318 Gene3D G3DSA:3.30.200.20 93 200 2.2E-5 T 09-03-2017 UA74_RS09265 17c2705e4afea037886e5bde757ff0e7 318 Gene3D G3DSA:1.10.510.10 218 291 1.2E-15 T 09-03-2017 UA74_RS09265 17c2705e4afea037886e5bde757ff0e7 318 SMART SM00090 81 310 1.8E-8 T 09-03-2017 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 UA74_RS09265 17c2705e4afea037886e5bde757ff0e7 318 Pfam PF01163 RIO1 family 140 295 5.4E-31 T 09-03-2017 UA74_RS09265 17c2705e4afea037886e5bde757ff0e7 318 SUPERFAMILY SSF56112 90 282 8.63E-16 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS30355 f06220e689541e08201f3f2bc82de516 193 Pfam PF02622 Uncharacterized ACR, COG1678 20 176 9.3E-36 T 09-03-2017 IPR003774 Protein of unknown function UPF0301 UA74_RS30355 f06220e689541e08201f3f2bc82de516 193 Gene3D G3DSA:3.40.1740.10 9 48 2.2E-23 T 09-03-2017 UA74_RS30355 f06220e689541e08201f3f2bc82de516 193 Gene3D G3DSA:3.40.1740.10 134 177 2.2E-23 T 09-03-2017 UA74_RS30355 f06220e689541e08201f3f2bc82de516 193 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 9 190 24.543 T 09-03-2017 IPR003774 Protein of unknown function UPF0301 UA74_RS30355 f06220e689541e08201f3f2bc82de516 193 SUPERFAMILY SSF143456 9 187 8.63E-47 T 09-03-2017 UA74_RS13005 4bf9e053eb1a3e5476d66aecaf46841d 452 Pfam PF03136 Pup-ligase protein 4 422 2.6E-156 T 09-03-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UA74_RS13005 4bf9e053eb1a3e5476d66aecaf46841d 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.679 T 09-03-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 UA74_RS13005 4bf9e053eb1a3e5476d66aecaf46841d 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 2.3E-235 T 09-03-2017 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 UA74_RS13005 4bf9e053eb1a3e5476d66aecaf46841d 452 PIRSF PIRSF018077 1 452 2.4E-181 T 09-03-2017 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UA74_RS13610 dd1a6e26240c6c9b848347294ca2014a 334 Pfam PF01636 Phosphotransferase enzyme family 24 243 3.0E-42 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS13610 dd1a6e26240c6c9b848347294ca2014a 334 SUPERFAMILY SSF56112 4 306 1.75E-52 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS13610 dd1a6e26240c6c9b848347294ca2014a 334 Gene3D G3DSA:3.90.1200.10 126 308 1.9E-29 T 09-03-2017 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01270 Histone deacetylase superfamily signature 164 179 1.0E-17 T 09-03-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01270 Histone deacetylase superfamily signature 250 260 1.0E-17 T 09-03-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01270 Histone deacetylase superfamily signature 131 154 1.0E-17 T 09-03-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 108 121 7.2E-5 T 09-03-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 7.2E-5 T 09-03-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 87 101 7.2E-5 T 09-03-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 Gene3D G3DSA:3.40.800.20 4 330 1.6E-89 T 09-03-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 Pfam PF00850 Histone deacetylase domain 21 321 1.3E-74 T 09-03-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_RS08845 06c54bd9c1a632f55649f6c5c0602f2a 403 SUPERFAMILY SSF52768 4 338 3.12E-100 T 09-03-2017 UA74_RS21220 5c5f03587b6061695dd5f249397fc9d3 54 SUPERFAMILY SSF57829 4 54 2.81E-17 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_RS21220 5c5f03587b6061695dd5f249397fc9d3 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.25 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21220 5c5f03587b6061695dd5f249397fc9d3 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 8.0E-23 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21220 5c5f03587b6061695dd5f249397fc9d3 54 Pfam PF00471 Ribosomal protein L33 9 54 3.7E-16 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS12945 e16a91d307db99e38bac9c427e90515c 238 SUPERFAMILY SSF81995 4 74 1.36E-6 T 09-03-2017 UA74_RS12945 e16a91d307db99e38bac9c427e90515c 238 Pfam PF12870 Domain of unknown function (DUF4878) 112 199 3.1E-6 T 09-03-2017 IPR024267 Domain of unknown function (DUF4878) UA74_RS07970 7b87e49d517d6930f36ba92b0194b403 1661 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 94 1657 0.0 T 09-03-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 UA74_RS07970 7b87e49d517d6930f36ba92b0194b403 1661 PIRSF PIRSF036761 20 1661 0.0 T 09-03-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 UA74_RS07970 7b87e49d517d6930f36ba92b0194b403 1661 Gene3D G3DSA:3.40.50.720 988 1099 3.6E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07970 7b87e49d517d6930f36ba92b0194b403 1661 Gene3D G3DSA:3.40.50.720 1144 1228 3.6E-36 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07970 7b87e49d517d6930f36ba92b0194b403 1661 SUPERFAMILY SSF53223 805 986 2.01E-21 T 09-03-2017 UA74_RS07970 7b87e49d517d6930f36ba92b0194b403 1661 SUPERFAMILY SSF51735 991 1093 7.88E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07970 7b87e49d517d6930f36ba92b0194b403 1661 SUPERFAMILY SSF51735 1131 1259 7.88E-27 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS08240 8568993f37697d92a4fa46968a5a581c 308 Gene3D G3DSA:3.40.50.300 5 229 7.4E-72 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08240 8568993f37697d92a4fa46968a5a581c 308 Pfam PF00005 ABC transporter 22 164 2.5E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS08240 8568993f37697d92a4fa46968a5a581c 308 SMART SM00382 30 213 2.1E-11 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08240 8568993f37697d92a4fa46968a5a581c 308 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS08240 8568993f37697d92a4fa46968a5a581c 308 SUPERFAMILY SSF52540 6 227 1.33E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS12775 5ffe72fe993e17582be6a9005b2fe00e 409 Gene3D G3DSA:2.120.10.10 54 404 6.4E-89 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS12775 5ffe72fe993e17582be6a9005b2fe00e 409 SUPERFAMILY SSF50939 49 404 1.09E-92 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS12775 5ffe72fe993e17582be6a9005b2fe00e 409 Pfam PF13088 BNR repeat-like domain 72 380 1.4E-39 T 09-03-2017 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_RS22750 112255aba45eed87cf59dd0151b1ce7d 238 Pfam PF01925 Sulfite exporter TauE/SafE 9 230 1.8E-20 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_RS22115 03fd8fcc1d8a54532b43a61d4ce95c8d 195 Gene3D G3DSA:1.10.260.40 23 86 2.5E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22115 03fd8fcc1d8a54532b43a61d4ce95c8d 195 SMART SM00530 29 85 2.5E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS22115 03fd8fcc1d8a54532b43a61d4ce95c8d 195 SUPERFAMILY SSF47413 26 88 1.07E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22115 03fd8fcc1d8a54532b43a61d4ce95c8d 195 Pfam PF13560 Helix-turn-helix domain 30 83 1.2E-11 T 09-03-2017 UA74_RS10335 25c7e377ff0328402943a1c1d3549631 142 Gene3D G3DSA:3.30.70.1060 1 117 7.3E-42 T 09-03-2017 UA74_RS10335 25c7e377ff0328402943a1c1d3549631 142 Pfam PF03795 YCII-related domain 1 114 8.2E-25 T 09-03-2017 IPR005545 YCII-related UA74_RS10335 25c7e377ff0328402943a1c1d3549631 142 SUPERFAMILY SSF54909 1 118 7.51E-36 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS02645 9f2e3134a5ee0d4eb8599b5f63b1cd6d 264 Pfam PF02274 Amidinotransferase 1 165 5.9E-8 T 09-03-2017 UA74_RS02645 9f2e3134a5ee0d4eb8599b5f63b1cd6d 264 SUPERFAMILY SSF55909 2 263 1.45E-47 T 09-03-2017 UA74_RS02645 9f2e3134a5ee0d4eb8599b5f63b1cd6d 264 Gene3D G3DSA:3.75.10.10 1 262 4.9E-58 T 09-03-2017 UA74_RS18195 2868920dd7233ee779d86297cb031326 425 Gene3D G3DSA:3.40.190.10 322 381 1.0E-27 T 09-03-2017 UA74_RS18195 2868920dd7233ee779d86297cb031326 425 Gene3D G3DSA:3.40.190.10 53 166 1.0E-27 T 09-03-2017 UA74_RS18195 2868920dd7233ee779d86297cb031326 425 SUPERFAMILY SSF53850 53 405 1.32E-62 T 09-03-2017 UA74_RS18195 2868920dd7233ee779d86297cb031326 425 Pfam PF13416 Bacterial extracellular solute-binding protein 71 369 1.3E-33 T 09-03-2017 UA74_RS18195 2868920dd7233ee779d86297cb031326 425 Gene3D G3DSA:3.40.190.10 167 321 4.7E-24 T 09-03-2017 UA74_RS09335 42a7e505ffed9b724400241c6f342b6c 98 Pfam PF04456 Protein of unknown function (DUF503) 3 89 4.5E-33 T 09-03-2017 IPR007546 Protein of unknown function DUF503 UA74_RS09335 42a7e505ffed9b724400241c6f342b6c 98 SUPERFAMILY SSF103007 2 94 1.57E-30 T 09-03-2017 IPR007546 Protein of unknown function DUF503 UA74_RS09335 42a7e505ffed9b724400241c6f342b6c 98 Gene3D G3DSA:3.30.70.1120 2 97 1.6E-35 T 09-03-2017 IPR007546 Protein of unknown function DUF503 UA74_RS04990 d344d5a88759037b75f11da5dacf3455 352 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 141 1.1E-19 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS04990 d344d5a88759037b75f11da5dacf3455 352 SUPERFAMILY SSF55961 174 351 1.91E-14 T 09-03-2017 UA74_RS04990 d344d5a88759037b75f11da5dacf3455 352 Gene3D G3DSA:3.30.530.20 7 168 6.7E-43 T 09-03-2017 IPR023393 START-like domain UA74_RS04990 d344d5a88759037b75f11da5dacf3455 352 Gene3D G3DSA:3.30.530.20 174 351 1.4E-19 T 09-03-2017 IPR023393 START-like domain UA74_RS04990 d344d5a88759037b75f11da5dacf3455 352 SUPERFAMILY SSF55961 7 149 2.55E-36 T 09-03-2017 UA74_RS21525 122755ff184d2168b20a843e6da8532e 313 Gene3D G3DSA:3.40.50.300 64 312 4.9E-69 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21525 122755ff184d2168b20a843e6da8532e 313 Pfam PF13614 AAA domain 63 239 2.8E-59 T 09-03-2017 IPR025669 AAA domain UA74_RS21525 122755ff184d2168b20a843e6da8532e 313 SUPERFAMILY SSF52540 62 312 7.93E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.6E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.6E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-47 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 SUPERFAMILY SSF51735 7 250 1.26E-83 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 2.2E-68 T 09-03-2017 UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 Gene3D G3DSA:3.40.50.720 3 250 5.8E-88 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.8E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.8E-13 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS13665 e5a9fab0c7a7ae883b26db7f40d23461 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.6E-4 T 09-03-2017 UA74_RS19690 89c52ba5a7eaf5212ed6ca7fc3818439 405 SUPERFAMILY SSF50969 283 399 1.57E-21 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_RS19690 89c52ba5a7eaf5212ed6ca7fc3818439 405 SUPERFAMILY SSF50969 63 253 1.57E-21 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_RS19690 89c52ba5a7eaf5212ed6ca7fc3818439 405 Gene3D G3DSA:2.130.10.10 63 399 2.4E-19 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS12080 0e7f1eb364750f284b6882b044f57969 383 Pfam PF01636 Phosphotransferase enzyme family 51 250 4.7E-7 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS12080 0e7f1eb364750f284b6882b044f57969 383 SUPERFAMILY SSF56112 20 303 5.39E-21 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS12080 0e7f1eb364750f284b6882b044f57969 383 Gene3D G3DSA:3.90.1200.10 112 289 4.2E-7 T 09-03-2017 UA74_RS08230 8922295e32c0dee86bf01ab4a8342f93 127 Pfam PF14017 Protein of unknown function (DUF4233) 13 115 5.3E-23 T 09-03-2017 IPR025327 Protein of unknown function DUF4233 UA74_RS08625 71ded7d135a7780cfe0b0b9219242e2f 150 SUPERFAMILY SSF50118 37 141 7.85E-9 T 09-03-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor UA74_RS08625 71ded7d135a7780cfe0b0b9219242e2f 150 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 40 141 7.0E-7 T 09-03-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 UA74_RS09900 216cad6a3c6530ab61fe57a755e7a9be 70 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 19 62 5.0E-8 T 09-03-2017 UA74_RS11780 3a535845ff4e47b973642c05357eb1ec 246 Pfam PF03741 Integral membrane protein TerC family 15 201 2.5E-47 T 09-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 UA74_RS16420 a8186eef7f93681a942def133c7456c3 169 Pfam PF08388 Group II intron, maturase-specific domain 70 145 2.7E-12 T 09-03-2017 IPR013597 Group II intron, maturase-specific UA74_RS16420 a8186eef7f93681a942def133c7456c3 169 SUPERFAMILY SSF56672 2 105 6.37E-5 T 09-03-2017 UA74_RS27495 3da5acee58b059bc134055e9791c90fe 295 SMART SM00530 24 79 5.5E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS27495 3da5acee58b059bc134055e9791c90fe 295 SUPERFAMILY SSF47413 15 71 2.42E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS27495 3da5acee58b059bc134055e9791c90fe 295 Pfam PF13560 Helix-turn-helix domain 20 71 2.9E-12 T 09-03-2017 UA74_RS27495 3da5acee58b059bc134055e9791c90fe 295 Gene3D G3DSA:1.10.260.40 15 73 1.6E-16 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23310 827f95dc6a2ae53a883372278633efe1 448 SUPERFAMILY SSF53383 22 441 2.82E-120 T 09-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase UA74_RS23310 827f95dc6a2ae53a883372278633efe1 448 Gene3D G3DSA:3.40.640.10 23 306 2.9E-121 T 09-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 UA74_RS23310 827f95dc6a2ae53a883372278633efe1 448 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 218 232 - T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS23310 827f95dc6a2ae53a883372278633efe1 448 Gene3D G3DSA:3.90.1150.10 308 444 1.2E-45 T 09-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 UA74_RS23310 827f95dc6a2ae53a883372278633efe1 448 PIRSF PIRSF001434 13 445 4.6E-129 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS23310 827f95dc6a2ae53a883372278633efe1 448 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 24 441 8.2E-197 T 09-03-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 UA74_RS23310 827f95dc6a2ae53a883372278633efe1 448 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 25 441 2.5E-139 T 09-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_RS24920 e653c0518d6eca0f642967afe373aef8 575 Gene3D G3DSA:1.10.287.1060 74 124 2.7E-4 T 09-03-2017 UA74_RS24920 e653c0518d6eca0f642967afe373aef8 575 SUPERFAMILY SSF140453 74 162 9.68E-8 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS06200 c31de44c7eed8bbba7a3a252ffb32ca0 169 Gene3D G3DSA:1.10.10.10 2 104 1.3E-32 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06200 c31de44c7eed8bbba7a3a252ffb32ca0 169 SUPERFAMILY SSF46785 5 144 3.1E-40 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS06200 c31de44c7eed8bbba7a3a252ffb32ca0 169 Pfam PF01638 HxlR-like helix-turn-helix 19 104 3.3E-23 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS07385 3f51a4fc6986dfc2a7c1eaedb4ff19c4 470 Pfam PF01757 Acyltransferase family 27 341 2.2E-15 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS08810 5df22ba10c0d90be7961d4c6e0732014 352 Pfam PF13830 Domain of unknown function (DUF4192) 14 326 4.1E-76 T 09-03-2017 IPR025447 Protein of unknown function DUF4192 UA74_RS24195 b3ec44c4023b2c613b4385a08246309b 394 SUPERFAMILY SSF56601 2 389 4.83E-85 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS24195 b3ec44c4023b2c613b4385a08246309b 394 Gene3D G3DSA:3.40.710.10 3 390 9.6E-83 T 09-03-2017 IPR012338 Beta-lactamase/transpeptidase-like UA74_RS24195 b3ec44c4023b2c613b4385a08246309b 394 Pfam PF00144 Beta-lactamase 10 387 3.2E-68 T 09-03-2017 IPR001466 Beta-lactamase-related UA74_RS10955 304179eb08565b00662dedc8234d914d 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 3.3E-62 T 09-03-2017 UA74_RS10955 304179eb08565b00662dedc8234d914d 245 Gene3D G3DSA:3.40.50.720 3 244 1.2E-80 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.5E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.5E-36 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.6E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.6E-10 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS10955 304179eb08565b00662dedc8234d914d 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 190 7.9E-5 T 09-03-2017 UA74_RS10955 304179eb08565b00662dedc8234d914d 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS10955 304179eb08565b00662dedc8234d914d 245 SUPERFAMILY SSF51735 7 244 4.53E-78 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14135 a06cfb57f2aa6bdc362ddebe11906f69 127 Pfam PF11236 Protein of unknown function (DUF3037) 9 126 1.1E-38 T 09-03-2017 IPR021398 Protein of unknown function DUF3037 UA74_RS11420 469966c5cb0e2ac57bea5af3cdb1ab50 152 SUPERFAMILY SSF47413 43 83 3.75E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS11420 469966c5cb0e2ac57bea5af3cdb1ab50 152 Gene3D G3DSA:1.10.260.40 43 101 5.0E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS25870 908379a7e8e6a6d5631ffce5f2bb5796 65 Pfam PF04149 Domain of unknown function (DUF397) 8 60 1.5E-16 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS11110 9f3dcee12558ba71da346f2c2ab0a17b 100 Gene3D G3DSA:3.30.70.900 14 83 6.4E-16 T 09-03-2017 UA74_RS11110 9f3dcee12558ba71da346f2c2ab0a17b 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 17 74 5.3E-9 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS11110 9f3dcee12558ba71da346f2c2ab0a17b 100 SUPERFAMILY SSF54909 10 98 1.83E-17 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS06460 32bc85eeea6f08b4691288f4c9015ea8 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 251 9.3E-66 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 UA74_RS06460 32bc85eeea6f08b4691288f4c9015ea8 259 Gene3D G3DSA:1.10.12.10 201 248 3.3E-14 T 09-03-2017 IPR014748 Crontonase, C-terminal UA74_RS06460 32bc85eeea6f08b4691288f4c9015ea8 259 Gene3D G3DSA:3.90.226.10 4 196 9.5E-67 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS06460 32bc85eeea6f08b4691288f4c9015ea8 259 SUPERFAMILY SSF52096 3 255 7.91E-78 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS18070 95e4755a621ea0a4d1ba93777ca799a0 215 Pfam PF01738 Dienelactone hydrolase family 88 210 4.5E-6 T 09-03-2017 IPR002925 Dienelactone hydrolase GO:0016787 UA74_RS18070 95e4755a621ea0a4d1ba93777ca799a0 215 SUPERFAMILY SSF53474 5 213 2.11E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18070 95e4755a621ea0a4d1ba93777ca799a0 215 Gene3D G3DSA:3.40.50.1820 7 214 2.6E-38 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS24875 1cdc0d62666e40fbab449399df1e0c79 88 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 8 68 5.5E-10 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS24875 1cdc0d62666e40fbab449399df1e0c79 88 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 51 2.5E-10 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS24875 1cdc0d62666e40fbab449399df1e0c79 88 SUPERFAMILY SSF143120 7 70 7.98E-9 T 09-03-2017 UA74_RS24875 1cdc0d62666e40fbab449399df1e0c79 88 Gene3D G3DSA:3.40.1620.10 6 45 4.8E-6 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS01855 9a708d83069ea0c2cc56b7107ecf167b 227 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 130 219 1.3E-10 T 09-03-2017 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_RS04475 18f37c49573a0efb538279c53f16f7e2 569 Pfam PF06259 Alpha/beta hydrolase 312 490 1.2E-39 T 09-03-2017 IPR010427 Protein of unknown function DUF1023 UA74_RS04475 18f37c49573a0efb538279c53f16f7e2 569 SUPERFAMILY SSF53474 318 500 2.07E-5 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS04475 18f37c49573a0efb538279c53f16f7e2 569 SUPERFAMILY SSF140453 11 94 1.83E-5 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS04475 18f37c49573a0efb538279c53f16f7e2 569 Gene3D G3DSA:3.40.50.1820 328 466 2.7E-4 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18055 0e7ca215e75c3e1a9f7e8cfad1302ac0 276 Gene3D G3DSA:3.40.50.720 2 208 1.4E-39 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18055 0e7ca215e75c3e1a9f7e8cfad1302ac0 276 SUPERFAMILY SSF51735 2 267 3.12E-52 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18055 0e7ca215e75c3e1a9f7e8cfad1302ac0 276 Pfam PF13460 NAD(P)H-binding 7 175 1.6E-26 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12855 0d5d37592bd803fe75646e33e761d3a7 502 SUPERFAMILY SSF53474 4 462 3.28E-90 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12855 0d5d37592bd803fe75646e33e761d3a7 502 Gene3D G3DSA:3.40.50.1820 4 457 1.6E-101 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12855 0d5d37592bd803fe75646e33e761d3a7 502 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 171 186 - T 09-03-2017 IPR019826 Carboxylesterase type B, active site UA74_RS12855 0d5d37592bd803fe75646e33e761d3a7 502 Pfam PF00135 Carboxylesterase family 4 457 6.3E-78 T 09-03-2017 IPR002018 Carboxylesterase, type B UA74_RS14110 2c9cfc6b989863c80fdb32b7adb3298c 264 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 12 264 1.3E-114 T 09-03-2017 IPR022292 Conserved hypothetical protein CHP03843 UA74_RS18815 cc03e46f0573344f2a06ee17041bfbc3 301 Gene3D G3DSA:3.40.50.720 1 127 1.4E-12 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18815 cc03e46f0573344f2a06ee17041bfbc3 301 SUPERFAMILY SSF51735 1 138 1.37E-11 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18815 cc03e46f0573344f2a06ee17041bfbc3 301 SUPERFAMILY SSF51735 165 178 1.37E-11 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS18815 cc03e46f0573344f2a06ee17041bfbc3 301 SUPERFAMILY SSF55347 141 249 1.96E-5 T 09-03-2017 UA74_RS18815 cc03e46f0573344f2a06ee17041bfbc3 301 Gene3D G3DSA:3.30.360.10 128 300 1.3E-8 T 09-03-2017 UA74_RS01975 9be2877e1db4a9440e7116d98c25c893 347 Gene3D G3DSA:3.40.50.10490 181 346 3.2E-34 T 09-03-2017 UA74_RS01975 9be2877e1db4a9440e7116d98c25c893 347 Pfam PF01380 SIS domain 47 167 1.8E-15 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS01975 9be2877e1db4a9440e7116d98c25c893 347 Pfam PF01380 SIS domain 207 327 1.9E-11 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS01975 9be2877e1db4a9440e7116d98c25c893 347 Gene3D G3DSA:3.40.50.10490 12 170 6.0E-29 T 09-03-2017 UA74_RS01975 9be2877e1db4a9440e7116d98c25c893 347 SUPERFAMILY SSF53697 10 345 1.06E-65 T 09-03-2017 UA74_RS05380 ee02377490fda364e077cf15c8ef74bc 346 Gene3D G3DSA:3.40.50.150 134 320 7.3E-12 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS05380 ee02377490fda364e077cf15c8ef74bc 346 SUPERFAMILY SSF53335 136 294 1.24E-13 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS23555 ae03c8546c08dc1dbfcd73d0e2d3e06d 276 Gene3D G3DSA:1.10.10.10 43 152 3.9E-21 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23555 ae03c8546c08dc1dbfcd73d0e2d3e06d 276 SMART SM00347 38 138 2.3E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS23555 ae03c8546c08dc1dbfcd73d0e2d3e06d 276 Pfam PF01047 MarR family 46 103 2.5E-9 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS23555 ae03c8546c08dc1dbfcd73d0e2d3e06d 276 SUPERFAMILY SSF46785 44 154 6.75E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23555 ae03c8546c08dc1dbfcd73d0e2d3e06d 276 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 09-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_RS18955 61a4688226c2ad5fb3bd6aae4cb742e3 296 Gene3D G3DSA:1.10.3720.10 22 284 2.9E-53 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18955 61a4688226c2ad5fb3bd6aae4cb742e3 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 283 6.4E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18955 61a4688226c2ad5fb3bd6aae4cb742e3 296 SUPERFAMILY SSF161098 31 291 1.44E-54 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS19750 590323ee2ee7916e57deb0e0b056e4c0 417 SUPERFAMILY SSF103473 31 410 5.36E-36 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS19750 590323ee2ee7916e57deb0e0b056e4c0 417 Gene3D G3DSA:1.20.1250.20 243 405 3.3E-6 T 09-03-2017 UA74_RS19750 590323ee2ee7916e57deb0e0b056e4c0 417 Gene3D G3DSA:1.20.1250.20 26 205 5.0E-18 T 09-03-2017 UA74_RS19750 590323ee2ee7916e57deb0e0b056e4c0 417 Pfam PF07690 Major Facilitator Superfamily 34 369 8.1E-20 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS19675 eb0f4091b7eb89afec4efd181989e9ec 368 SUPERFAMILY SSF48371 40 241 3.06E-30 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 UA74_RS19675 eb0f4091b7eb89afec4efd181989e9ec 368 Gene3D G3DSA:1.25.10.10 97 251 3.6E-4 T 09-03-2017 IPR011989 Armadillo-like helical UA74_RS25005 7b6d182a65b06aac70763ebaf19540dc 378 Pfam PF00534 Glycosyl transferases group 1 185 358 2.4E-42 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS25005 7b6d182a65b06aac70763ebaf19540dc 378 Pfam PF13439 Glycosyltransferase Family 4 15 174 6.9E-13 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS25005 7b6d182a65b06aac70763ebaf19540dc 378 Gene3D G3DSA:3.40.50.2000 167 356 1.8E-38 T 09-03-2017 UA74_RS25005 7b6d182a65b06aac70763ebaf19540dc 378 SUPERFAMILY SSF53756 4 376 3.14E-77 T 09-03-2017 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 2.0E-21 T 09-03-2017 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 1.3E-44 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 Gene3D G3DSA:1.10.1900.20 56 117 2.1E-29 T 09-03-2017 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.3E-38 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.3E-38 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.3E-38 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 SUPERFAMILY SSF74731 3 117 4.58E-46 T 09-03-2017 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.537 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21750 b8f114ce4dc36f034db45dc9e9116fa5 126 Pfam PF00453 Ribosomal protein L20 3 108 6.8E-45 T 09-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS25395 3af251cb1e9f1e871dfadd9afe26e7e7 81 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 19 81 9.0E-9 T 09-03-2017 IPR020311 Uncharacterised protein family, Rv0898c UA74_RS25395 3af251cb1e9f1e871dfadd9afe26e7e7 81 Pfam PF10944 Protein of unknown function (DUF2630) 3 81 9.0E-26 T 09-03-2017 IPR020311 Uncharacterised protein family, Rv0898c UA74_RS19815 c8bce06a5c125252cef4c132ad6e4898 148 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.3E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS19815 c8bce06a5c125252cef4c132ad6e4898 148 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.3E-7 T 09-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_RS19815 c8bce06a5c125252cef4c132ad6e4898 148 Pfam PF00293 NUDIX domain 22 124 8.2E-16 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS19815 c8bce06a5c125252cef4c132ad6e4898 148 Gene3D G3DSA:3.90.79.10 23 126 6.1E-25 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS19815 c8bce06a5c125252cef4c132ad6e4898 148 SUPERFAMILY SSF55811 23 127 2.71E-24 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS19815 c8bce06a5c125252cef4c132ad6e4898 148 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS05575 5c19ffcfbd74bc542a1553435cb26ebd 229 SUPERFAMILY SSF46689 8 81 3.28E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS05575 5c19ffcfbd74bc542a1553435cb26ebd 229 Gene3D G3DSA:1.10.357.10 4 173 1.1E-20 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS05575 5c19ffcfbd74bc542a1553435cb26ebd 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 8.1E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 Gene3D G3DSA:3.20.20.100 7 268 4.6E-86 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 158 187 4.0E-38 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 92 110 4.0E-38 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 196 220 4.0E-38 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 124 141 4.0E-38 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 36 60 4.0E-38 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 Pfam PF00248 Aldo/keto reductase family 17 259 2.7E-39 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS19720 f7d0913739d22a5a5a5d87db1b8e41bf 278 SUPERFAMILY SSF51430 9 265 1.31E-79 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS18520 e2b612f9a5b65c30c8574e72d9d2fd93 317 Gene3D G3DSA:3.30.420.10 95 239 2.8E-12 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS18520 e2b612f9a5b65c30c8574e72d9d2fd93 317 SUPERFAMILY SSF53098 96 238 7.08E-10 T 09-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 UA74_RS01385 d66a190475ec6cc2b17b649c3716ef85 122 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 15 61 8.8E-7 T 09-03-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal UA74_RS01385 d66a190475ec6cc2b17b649c3716ef85 122 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 13 120 3.7E-26 T 09-03-2017 IPR021202 Helicase/secretion neighbourhood TadE-like protein UA74_RS30100 3849dc65a211a26a98fe4c3e609917e8 209 Pfam PF04402 Protein of unknown function (DUF541) 7 195 8.2E-27 T 09-03-2017 IPR007497 Protein of unknown function DUF541 UA74_RS20610 3d2c7dad9d4c01ed9fc51f8c6087eaed 749 Pfam PF03235 Protein of unknown function DUF262 4 208 2.7E-25 T 09-03-2017 IPR004919 Domain of unknown function DUF262 UA74_RS14430 6c939cb61f6150e1c525b8fad77fe4d4 367 Gene3D G3DSA:2.115.10.20 94 332 1.5E-27 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS14430 6c939cb61f6150e1c525b8fad77fe4d4 367 Pfam PF04616 Glycosyl hydrolases family 43 97 310 6.0E-8 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_RS14430 6c939cb61f6150e1c525b8fad77fe4d4 367 SUPERFAMILY SSF75005 94 349 5.8E-30 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS10980 32a3dcf97e5b9f05a2b6e90f20a6dbb9 471 Pfam PF00999 Sodium/hydrogen exchanger family 55 441 8.1E-51 T 09-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UA74_RS11065 de073335b424d037b0ca931b79c06014 111 SUPERFAMILY SSF54909 2 105 2.57E-42 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS11065 de073335b424d037b0ca931b79c06014 111 Pfam PF04673 Polyketide synthesis cyclase 2 104 2.4E-41 T 09-03-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 UA74_RS11065 de073335b424d037b0ca931b79c06014 111 Gene3D G3DSA:3.30.70.1090 1 106 3.4E-44 T 09-03-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 UA74_RS11065 de073335b424d037b0ca931b79c06014 111 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 103 1.0E-41 T 09-03-2017 IPR006765 Polyketide synthesis cyclase GO:0030639 UA74_RS20820 96f345bcf9e83f27907a18919c28b831 151 Pfam PF04965 Gene 25-like lysozyme 27 116 4.8E-25 T 09-03-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD UA74_RS20820 96f345bcf9e83f27907a18919c28b831 151 Gene3D G3DSA:3.10.450.40 2 128 3.2E-45 T 09-03-2017 UA74_RS20820 96f345bcf9e83f27907a18919c28b831 151 SUPERFAMILY SSF160719 22 129 3.53E-34 T 09-03-2017 UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 284 7.1E-88 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 39.463 T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 09-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 Pfam PF00557 Metallopeptidase family M24 48 276 1.9E-50 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.4E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.4E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.4E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.4E-20 T 09-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 Gene3D G3DSA:3.90.230.10 41 284 1.3E-93 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS09130 bbe9578b48d5e0116c7c63884d92b424 285 SUPERFAMILY SSF55920 4 283 5.23E-89 T 09-03-2017 IPR000994 Peptidase M24, structural domain UA74_RS03700 e9be77fa2002ee7ea975be197a0609b8 489 PIRSF PIRSF002746 2 489 2.9E-149 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_RS03700 e9be77fa2002ee7ea975be197a0609b8 489 Pfam PF02447 GntP family permease 264 485 5.1E-63 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_RS03700 e9be77fa2002ee7ea975be197a0609b8 489 Pfam PF02447 GntP family permease 8 206 1.9E-66 T 09-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_RS06315 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 299 1.0E-109 T 09-03-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 UA74_RS06315 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 287 4.2E-67 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS06315 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 09-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 UA74_RS06315 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 Gene3D G3DSA:3.40.50.1100 43 144 2.0E-38 T 09-03-2017 UA74_RS06315 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 Gene3D G3DSA:3.40.50.1100 2 42 1.6E-65 T 09-03-2017 UA74_RS06315 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 Gene3D G3DSA:3.40.50.1100 150 302 1.6E-65 T 09-03-2017 UA74_RS06315 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 SUPERFAMILY SSF53686 2 298 1.11E-85 T 09-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_RS10375 de3b616dea0202b61aa1a4fefcf3cc99 284 Pfam PF01551 Peptidase family M23 55 150 2.3E-25 T 09-03-2017 IPR016047 Peptidase M23 UA74_RS10375 de3b616dea0202b61aa1a4fefcf3cc99 284 SUPERFAMILY SSF51261 55 150 9.42E-30 T 09-03-2017 IPR011055 Duplicated hybrid motif UA74_RS10375 de3b616dea0202b61aa1a4fefcf3cc99 284 Gene3D G3DSA:2.70.70.10 25 150 1.0E-31 T 09-03-2017 UA74_RS15710 c9e645a6bdfc6a91bc7dc466145bea9c 353 SUPERFAMILY SSF101898 77 162 2.56E-15 T 09-03-2017 UA74_RS15710 c9e645a6bdfc6a91bc7dc466145bea9c 353 SUPERFAMILY SSF101898 197 352 2.56E-15 T 09-03-2017 UA74_RS15710 c9e645a6bdfc6a91bc7dc466145bea9c 353 Gene3D G3DSA:2.130.10.10 74 163 7.3E-13 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS15710 c9e645a6bdfc6a91bc7dc466145bea9c 353 Gene3D G3DSA:2.130.10.10 238 351 7.3E-13 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 8 684 0.0 T 09-03-2017 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 500 511 2.4E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 422 439 2.4E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 574 593 2.4E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 595 612 2.4E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 548 564 2.4E-21 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 Gene3D G3DSA:3.40.225.10 6 217 1.4E-32 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 Pfam PF00106 short chain dehydrogenase 422 607 3.1E-41 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 421 611 0.0045 T 09-03-2017 UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 SUPERFAMILY SSF51735 414 681 2.99E-55 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 SUPERFAMILY SSF53639 4 214 9.81E-31 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 Gene3D G3DSA:3.40.50.720 400 679 1.3E-57 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 208 4.0E-24 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS23945 8c2c1f63c712fd80c5c91033ef14d748 684 SMART SM01007 9 211 2.8E-31 T 09-03-2017 IPR001303 Class II aldolase/adducin N-terminal UA74_RS21620 c0a093f43ad10ba4bea25f0f7a429f0e 401 Gene3D G3DSA:1.25.40.10 160 197 8.6E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS21620 c0a093f43ad10ba4bea25f0f7a429f0e 401 Gene3D G3DSA:1.25.40.10 63 118 8.6E-4 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS12795 0563939785deafb6c253c5f237de6c0c 350 Gene3D G3DSA:3.90.180.10 1 171 1.6E-38 T 09-03-2017 IPR011032 GroES-like UA74_RS12795 0563939785deafb6c253c5f237de6c0c 350 SMART SM00829 10 344 2.9E-11 T 09-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_RS12795 0563939785deafb6c253c5f237de6c0c 350 Pfam PF00107 Zinc-binding dehydrogenase 180 307 7.3E-23 T 09-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_RS12795 0563939785deafb6c253c5f237de6c0c 350 SUPERFAMILY SSF51735 142 311 5.22E-35 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12795 0563939785deafb6c253c5f237de6c0c 350 Gene3D G3DSA:3.40.50.720 172 314 5.7E-33 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS12795 0563939785deafb6c253c5f237de6c0c 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 138 3.0E-20 T 09-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_RS12795 0563939785deafb6c253c5f237de6c0c 350 SUPERFAMILY SSF50129 1 176 2.59E-41 T 09-03-2017 IPR011032 GroES-like UA74_RS29295 d3b79e76608f1dfe0493011feb63ab8c 234 Pfam PF12697 Alpha/beta hydrolase family 1 183 1.5E-11 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS29295 d3b79e76608f1dfe0493011feb63ab8c 234 SUPERFAMILY SSF53474 1 217 2.43E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS29295 d3b79e76608f1dfe0493011feb63ab8c 234 Gene3D G3DSA:3.40.50.1820 2 109 7.2E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS29295 d3b79e76608f1dfe0493011feb63ab8c 234 Gene3D G3DSA:3.40.50.1820 150 217 7.2E-33 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS13950 02ab8bf62b60a7dc855a90762e0050af 288 Gene3D G3DSA:3.20.20.150 47 286 4.1E-50 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS13950 02ab8bf62b60a7dc855a90762e0050af 288 Pfam PF01261 Xylose isomerase-like TIM barrel 72 245 1.9E-14 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS13950 02ab8bf62b60a7dc855a90762e0050af 288 SUPERFAMILY SSF51658 46 286 2.33E-37 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS26765 3eb2569ec08ad46c4fe68a58bdd55792 925 Gene3D G3DSA:3.40.50.1820 594 666 3.5E-5 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS26765 3eb2569ec08ad46c4fe68a58bdd55792 925 SUPERFAMILY SSF53474 594 658 1.87E-8 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 Gene3D G3DSA:3.30.70.100 3 67 2.1E-22 T 09-03-2017 UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 09-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 Pfam PF00403 Heavy-metal-associated domain 5 65 3.2E-16 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 SUPERFAMILY SSF55008 3 67 1.57E-18 T 09-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 PRINTS PR00944 Copper ion binding protein signature 3 15 7.6E-9 T 09-03-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 PRINTS PR00944 Copper ion binding protein signature 28 41 7.6E-9 T 09-03-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 PRINTS PR00944 Copper ion binding protein signature 53 66 7.6E-9 T 09-03-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_RS07400 457f4e7cede000a6d7795a327087ae98 68 PRINTS PR00944 Copper ion binding protein signature 15 28 7.6E-9 T 09-03-2017 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_RS15760 7a894a6cc547ae5b7437040bac9ea870 117 SUPERFAMILY SSF51182 16 116 2.51E-10 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS15760 7a894a6cc547ae5b7437040bac9ea870 117 Gene3D G3DSA:2.60.120.10 33 110 1.1E-8 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS10495 551f097604d3102780b7be4b45a1631b 187 Gene3D G3DSA:3.40.50.10490 3 184 4.2E-51 T 09-03-2017 UA74_RS10495 551f097604d3102780b7be4b45a1631b 187 SUPERFAMILY SSF53697 2 184 4.65E-45 T 09-03-2017 UA74_RS10495 551f097604d3102780b7be4b45a1631b 187 Pfam PF13580 SIS domain 20 140 2.1E-25 T 09-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 UA74_RS01040 37c4c639612d75054c9e4033dc253f3a 365 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 321 1.0E-26 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS01040 37c4c639612d75054c9e4033dc253f3a 365 SUPERFAMILY SSF52540 2 253 1.04E-71 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS01040 37c4c639612d75054c9e4033dc253f3a 365 Pfam PF00005 ABC transporter 30 181 1.5E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS01040 37c4c639612d75054c9e4033dc253f3a 365 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 299 2.8E-15 T 09-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_RS01040 37c4c639612d75054c9e4033dc253f3a 365 SMART SM00382 38 231 4.2E-17 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS01040 37c4c639612d75054c9e4033dc253f3a 365 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS01040 37c4c639612d75054c9e4033dc253f3a 365 Gene3D G3DSA:3.40.50.300 2 261 1.1E-78 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 14 253 4.7E-73 T 09-03-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 193 210 1.4E-43 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 235 253 1.4E-43 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 1.4E-43 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 89 110 1.4E-43 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 153 173 1.4E-43 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 130 152 1.4E-43 T 09-03-2017 IPR005511 Senescence marker protein-30 (SMP-30) UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 SUPERFAMILY SSF63829 11 282 2.13E-64 T 09-03-2017 UA74_RS03975 db9f7200b33afc0a9f5a9801276f38f1 289 Gene3D G3DSA:2.120.10.30 2 283 9.1E-83 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS05900 458dc8642f4506ce1aba1fce271bc78b 121 Gene3D G3DSA:3.30.460.10 2 70 3.2E-4 T 09-03-2017 UA74_RS18640 26a508ff3ef7eeccd472f59f2fded25c 120 Pfam PF03795 YCII-related domain 2 112 1.1E-11 T 09-03-2017 IPR005545 YCII-related UA74_RS18640 26a508ff3ef7eeccd472f59f2fded25c 120 SUPERFAMILY SSF54909 2 114 5.36E-29 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS18640 26a508ff3ef7eeccd472f59f2fded25c 120 Gene3D G3DSA:3.30.70.1060 2 114 3.6E-37 T 09-03-2017 UA74_RS08670 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 Gene3D G3DSA:1.10.3720.10 61 260 9.2E-39 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08670 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 151 8.2E-16 T 09-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 UA74_RS08670 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 SUPERFAMILY SSF161098 62 245 5.1E-36 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08670 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 260 8.6E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS11370 01d895538ba6b974f128df1fdfc0a759 293 SUPERFAMILY SSF81345 9 273 1.7E-17 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS11370 01d895538ba6b974f128df1fdfc0a759 293 Pfam PF00950 ABC 3 transport family 9 274 3.4E-42 T 09-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_RS14460 7c2013ed22dbb2915b11ce07e18afbae 471 SUPERFAMILY SSF52129 79 207 1.15E-8 T 09-03-2017 IPR029030 Caspase-like domain UA74_RS14460 7c2013ed22dbb2915b11ce07e18afbae 471 Pfam PF00656 Caspase domain 57 223 2.6E-7 T 09-03-2017 UA74_RS12110 12ee9cf17f18f80ebdac41b67332d0ed 602 Pfam PF04183 IucA / IucC family 155 385 6.0E-56 T 09-03-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 UA74_RS12110 12ee9cf17f18f80ebdac41b67332d0ed 602 Pfam PF06276 Ferric iron reductase FhuF-like transporter 413 574 1.5E-29 T 09-03-2017 IPR022770 Ferric iron reductase FhuF domain UA74_RS12645 7cccb046668c905fdad961b63c5c043e 69 Pfam PF04149 Domain of unknown function (DUF397) 10 61 1.0E-14 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS23325 0f2a2cdd2b1ed496192aa37c11f9e7f5 318 Gene3D G3DSA:3.90.245.10 2 315 2.0E-86 T 09-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain UA74_RS23325 0f2a2cdd2b1ed496192aa37c11f9e7f5 318 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 6 16 - T 09-03-2017 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 UA74_RS23325 0f2a2cdd2b1ed496192aa37c11f9e7f5 318 SUPERFAMILY SSF53590 2 314 3.53E-80 T 09-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain UA74_RS23325 0f2a2cdd2b1ed496192aa37c11f9e7f5 318 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 2 308 2.3E-60 T 09-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain UA74_RS07160 544c3623e23aaa6df8cc6902f2ad9703 275 Gene3D G3DSA:1.10.520.20 109 181 2.5E-4 T 09-03-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 UA74_RS07160 544c3623e23aaa6df8cc6902f2ad9703 275 Hamap MF_01416 ATP synthase subunit delta [atpD]. 47 275 13.953 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 UA74_RS07160 544c3623e23aaa6df8cc6902f2ad9703 275 Pfam PF00213 ATP synthase delta (OSCP) subunit 110 273 6.3E-31 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 UA74_RS07160 544c3623e23aaa6df8cc6902f2ad9703 275 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 109 273 3.1E-20 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 UA74_RS07160 544c3623e23aaa6df8cc6902f2ad9703 275 PRINTS PR00125 ATP synthase delta subunit signature 233 248 2.3E-7 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 UA74_RS07160 544c3623e23aaa6df8cc6902f2ad9703 275 PRINTS PR00125 ATP synthase delta subunit signature 248 266 2.3E-7 T 09-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 UA74_RS07160 544c3623e23aaa6df8cc6902f2ad9703 275 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 235 254 - T 09-03-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 UA74_RS22715 6b553d829bad0be5ebee8173605453ed 306 Pfam PF00701 Dihydrodipicolinate synthetase family 15 301 3.2E-47 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS22715 6b553d829bad0be5ebee8173605453ed 306 SUPERFAMILY SSF51569 15 301 6.49E-65 T 09-03-2017 UA74_RS22715 6b553d829bad0be5ebee8173605453ed 306 Gene3D G3DSA:3.20.20.70 15 303 1.3E-74 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS22715 6b553d829bad0be5ebee8173605453ed 306 PIRSF PIRSF001365 12 306 3.1E-55 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS22715 6b553d829bad0be5ebee8173605453ed 306 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 6 303 5.0E-120 T 09-03-2017 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 UA74_RS22715 6b553d829bad0be5ebee8173605453ed 306 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 7 305 49.494 T 09-03-2017 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 UA74_RS22715 6b553d829bad0be5ebee8173605453ed 306 SMART SM01130 13 304 1.6E-65 T 09-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 UA74_RS08915 9968768d87914311f5807bb7d75df95e 237 Pfam PF02517 CAAX protease self-immunity 141 227 8.6E-13 T 09-03-2017 IPR003675 CAAX amino terminal protease GO:0016020 UA74_RS28425 8d77fce04810087bcd9ea230af96e67d 406 Gene3D G3DSA:1.20.1250.20 18 196 8.0E-17 T 09-03-2017 UA74_RS28425 8d77fce04810087bcd9ea230af96e67d 406 Gene3D G3DSA:1.20.1250.20 221 399 1.4E-8 T 09-03-2017 UA74_RS28425 8d77fce04810087bcd9ea230af96e67d 406 SUPERFAMILY SSF103473 14 399 3.66E-33 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS28425 8d77fce04810087bcd9ea230af96e67d 406 Pfam PF05977 Transmembrane secretion effector 8 395 9.3E-42 T 09-03-2017 IPR010290 Transmembrane secretion effector UA74_RS23300 81c19d594a00687589e2e5cff253c17f 450 Gene3D G3DSA:1.10.260.40 38 84 5.9E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23300 81c19d594a00687589e2e5cff253c17f 450 SMART SM00530 33 88 4.7E-4 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS23300 81c19d594a00687589e2e5cff253c17f 450 Pfam PF13560 Helix-turn-helix domain 34 86 1.0E-6 T 09-03-2017 UA74_RS23300 81c19d594a00687589e2e5cff253c17f 450 SUPERFAMILY SSF47413 35 85 2.55E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS23300 81c19d594a00687589e2e5cff253c17f 450 Gene3D G3DSA:1.25.40.10 205 436 1.4E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23300 81c19d594a00687589e2e5cff253c17f 450 SUPERFAMILY SSF48452 185 314 4.61E-10 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 Pfam PF00166 Chaperonin 10 Kd subunit 8 93 3.5E-18 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 PRINTS PR00297 10kDa chaperonin signature 60 72 4.5E-9 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 PRINTS PR00297 10kDa chaperonin signature 8 23 4.5E-9 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 PRINTS PR00297 10kDa chaperonin signature 34 55 4.5E-9 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 PRINTS PR00297 10kDa chaperonin signature 81 94 4.5E-9 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 Gene3D G3DSA:2.30.33.40 8 93 1.1E-18 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 SUPERFAMILY SSF50129 7 94 3.77E-19 T 09-03-2017 IPR011032 GroES-like UA74_RS29855 66c4cda410abefe9f8b53ba24c246f7e 106 SMART SM00883 7 94 5.2E-27 T 09-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_RS15785 7681fdcb0baa86106f99d8a2801603f2 613 Pfam PF13175 AAA ATPase domain 227 337 2.9E-15 T 09-03-2017 UA74_RS15785 7681fdcb0baa86106f99d8a2801603f2 613 Pfam PF13175 AAA ATPase domain 1 46 1.6E-11 T 09-03-2017 UA74_RS15785 7681fdcb0baa86106f99d8a2801603f2 613 SUPERFAMILY SSF52540 242 350 1.78E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15785 7681fdcb0baa86106f99d8a2801603f2 613 SUPERFAMILY SSF52540 1 143 1.78E-19 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS15785 7681fdcb0baa86106f99d8a2801603f2 613 Gene3D G3DSA:3.40.50.300 1 353 1.4E-27 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS22060 cf4232dcabd211b422be1c66a84f146b 141 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 26 122 3.1E-35 T 09-03-2017 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 UA74_RS18120 53492e8a35a3c250513805494535046d 260 Gene3D G3DSA:3.40.50.1820 5 252 1.1E-18 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS18120 53492e8a35a3c250513805494535046d 260 Pfam PF12697 Alpha/beta hydrolase family 47 241 4.5E-8 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS18120 53492e8a35a3c250513805494535046d 260 SUPERFAMILY SSF53474 4 253 2.1E-22 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25320 53fcd7733d708f9900f84d511fe190c4 172 SUPERFAMILY SSF109854 3 167 5.04E-40 T 09-03-2017 UA74_RS25320 53fcd7733d708f9900f84d511fe190c4 172 Gene3D G3DSA:1.20.120.450 2 172 9.7E-47 T 09-03-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase UA74_RS25320 53fcd7733d708f9900f84d511fe190c4 172 Pfam PF04978 Protein of unknown function (DUF664) 18 168 2.0E-42 T 09-03-2017 IPR007061 Protein of unknown function DUF664 UA74_RS17590 dd025ed0081e95aba136634374fbb5aa 468 Gene3D G3DSA:3.40.50.2000 1 252 7.0E-32 T 09-03-2017 UA74_RS17590 dd025ed0081e95aba136634374fbb5aa 468 Gene3D G3DSA:3.40.50.2000 399 440 2.7E-16 T 09-03-2017 UA74_RS17590 dd025ed0081e95aba136634374fbb5aa 468 Gene3D G3DSA:3.40.50.2000 253 356 2.7E-16 T 09-03-2017 UA74_RS17590 dd025ed0081e95aba136634374fbb5aa 468 Pfam PF06722 Protein of unknown function (DUF1205) 210 305 3.2E-21 T 09-03-2017 IPR010610 Domain of unknown function DUF1205 UA74_RS17590 dd025ed0081e95aba136634374fbb5aa 468 SUPERFAMILY SSF53756 398 461 6.73E-7 T 09-03-2017 UA74_RS17590 dd025ed0081e95aba136634374fbb5aa 468 SUPERFAMILY SSF53756 1 56 7.33E-60 T 09-03-2017 UA74_RS17590 dd025ed0081e95aba136634374fbb5aa 468 SUPERFAMILY SSF53756 89 344 7.33E-60 T 09-03-2017 UA74_RS14425 8520b80763289fedd113cd48e8321ac9 309 Pfam PF03547 Membrane transport protein 13 146 1.4E-7 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UA74_RS14425 8520b80763289fedd113cd48e8321ac9 309 Pfam PF03547 Membrane transport protein 163 303 8.8E-10 T 09-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UA74_RS15700 e13e644e9c23443b28454bee825088fb 348 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 321 1.2E-114 T 09-03-2017 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c UA74_RS15700 e13e644e9c23443b28454bee825088fb 348 Gene3D G3DSA:3.20.20.30 2 340 6.3E-75 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS15700 e13e644e9c23443b28454bee825088fb 348 Pfam PF00296 Luciferase-like monooxygenase 16 317 1.2E-78 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS15700 e13e644e9c23443b28454bee825088fb 348 SUPERFAMILY SSF51679 10 339 9.86E-68 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS08960 1728e01a1a63305258f4ce6824d99d82 108 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 2.7E-53 T 09-03-2017 IPR019592 Protein of unknown function DUF2469 UA74_RS16455 ae34c79b9ba4c06c917bb7df49a90e53 232 Gene3D G3DSA:3.40.50.300 86 106 0.001 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02450 59c87a3be8596ff0c7de19c3a91c503b 453 SUPERFAMILY SSF58104 174 340 7.46E-5 T 09-03-2017 UA74_RS20860 d8549fa1d1f777ae90f13a8c736dfa45 503 Pfam PF04984 Phage tail sheath protein 1 492 1.2E-88 T 09-03-2017 IPR007067 Tail sheath protein UA74_RS27540 d152b434fbf8a716ff220a4a60469583 279 Gene3D G3DSA:1.10.260.40 12 71 1.9E-14 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS27540 d152b434fbf8a716ff220a4a60469583 279 SMART SM00530 20 75 1.4E-13 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS27540 d152b434fbf8a716ff220a4a60469583 279 SUPERFAMILY SSF47413 10 71 3.67E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS27540 d152b434fbf8a716ff220a4a60469583 279 Pfam PF13560 Helix-turn-helix domain 16 78 9.4E-14 T 09-03-2017 UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 4.0E-9 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 SUPERFAMILY SSF48498 76 205 8.67E-24 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 SUPERFAMILY SSF46689 3 67 3.44E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 PRINTS PR00400 Tetracycline repressor protein signature 134 153 5.1E-8 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 PRINTS PR00400 Tetracycline repressor protein signature 187 201 5.1E-8 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 PRINTS PR00400 Tetracycline repressor protein signature 25 48 5.1E-8 T 09-03-2017 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 204 2.1E-17 T 09-03-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_RS20345 0d4521f9d07d4df6ad74a583e15bb555 212 Gene3D G3DSA:1.10.357.10 3 206 6.3E-52 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS18015 f601e306ff4c18fb5e4513e2b14377e0 284 SUPERFAMILY SSF63380 14 138 4.38E-11 T 09-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 UA74_RS18015 f601e306ff4c18fb5e4513e2b14377e0 284 Pfam PF08021 Siderophore-interacting FAD-binding domain 26 141 2.3E-41 T 09-03-2017 IPR013113 FAD-binding 9, siderophore-interacting UA74_RS18015 f601e306ff4c18fb5e4513e2b14377e0 284 Gene3D G3DSA:3.40.50.80 152 277 3.1E-43 T 09-03-2017 UA74_RS18015 f601e306ff4c18fb5e4513e2b14377e0 284 Pfam PF04954 Siderophore-interacting protein 156 273 1.8E-38 T 09-03-2017 IPR007037 Siderophore-interacting protein UA74_RS18015 f601e306ff4c18fb5e4513e2b14377e0 284 Gene3D G3DSA:2.40.30.10 15 139 8.4E-37 T 09-03-2017 UA74_RS08370 ec35aef12b28d97369a54562d8fad0e3 286 Gene3D G3DSA:3.40.50.10170 3 147 6.5E-45 T 09-03-2017 UA74_RS08370 ec35aef12b28d97369a54562d8fad0e3 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 2.9E-83 T 09-03-2017 IPR003797 DegV UA74_RS08370 ec35aef12b28d97369a54562d8fad0e3 286 Gene3D G3DSA:3.30.1180.10 153 279 4.2E-41 T 09-03-2017 UA74_RS08370 ec35aef12b28d97369a54562d8fad0e3 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 8.6E-88 T 09-03-2017 IPR003797 DegV UA74_RS08370 ec35aef12b28d97369a54562d8fad0e3 286 SUPERFAMILY SSF82549 2 279 7.85E-78 T 09-03-2017 UA74_RS10680 f358fff3a8a2f83a2fde8f242098baa3 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 325 1.1E-44 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS15865 1452bc841c8c50a3b17b208f2849e7b2 322 SUPERFAMILY SSF51430 24 320 2.75E-39 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS15865 1452bc841c8c50a3b17b208f2849e7b2 322 Gene3D G3DSA:3.20.20.100 24 320 2.9E-38 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS15865 1452bc841c8c50a3b17b208f2849e7b2 322 Pfam PF00248 Aldo/keto reductase family 25 301 5.5E-23 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS00930 79d4c8a8571e0dc1ea602531c22b1c52 317 PRINTS PR00069 Aldo-keto reductase signature 31 55 4.5E-10 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS00930 79d4c8a8571e0dc1ea602531c22b1c52 317 PRINTS PR00069 Aldo-keto reductase signature 126 143 4.5E-10 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS00930 79d4c8a8571e0dc1ea602531c22b1c52 317 PRINTS PR00069 Aldo-keto reductase signature 95 113 4.5E-10 T 09-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_RS00930 79d4c8a8571e0dc1ea602531c22b1c52 317 Pfam PF00248 Aldo/keto reductase family 7 304 1.7E-66 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS00930 79d4c8a8571e0dc1ea602531c22b1c52 317 SUPERFAMILY SSF51430 6 313 2.1E-83 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS00930 79d4c8a8571e0dc1ea602531c22b1c52 317 Gene3D G3DSA:3.20.20.100 6 314 4.4E-84 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS00930 79d4c8a8571e0dc1ea602531c22b1c52 317 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 09-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_RS04055 a1426498c5d582058e8e65e4a54752d6 292 Gene3D G3DSA:3.40.50.150 28 279 3.3E-62 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04055 a1426498c5d582058e8e65e4a54752d6 292 SUPERFAMILY SSF53335 36 245 2.95E-27 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS26910 24ab991efe24e9ccc0799d80b5d0aab9 260 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 7 251 1.2E-55 T 09-03-2017 IPR017523 Conserved hypothetical protein CHP03089 UA74_RS26910 24ab991efe24e9ccc0799d80b5d0aab9 260 Gene3D G3DSA:3.40.50.980 190 254 2.1E-5 T 09-03-2017 UA74_RS26910 24ab991efe24e9ccc0799d80b5d0aab9 260 SUPERFAMILY SSF56801 8 254 1.96E-16 T 09-03-2017 UA74_RS13175 0dad6de2de7e10fd7f1ecb3aed8b8a07 376 Pfam PF02361 Cobalt transport protein 27 238 8.2E-9 T 09-03-2017 IPR003339 ABC/ECF transporter, transmembrane component UA74_RS14980 cb8529a2f8441e6e29e3f0ded953c793 116 SUPERFAMILY SSF54184 20 82 1.57E-7 T 09-03-2017 UA74_RS14980 cb8529a2f8441e6e29e3f0ded953c793 116 SMART SM00740 16 84 0.0017 T 09-03-2017 IPR005543 PASTA domain UA74_RS14980 cb8529a2f8441e6e29e3f0ded953c793 116 Pfam PF03793 PASTA domain 20 82 5.1E-10 T 09-03-2017 IPR005543 PASTA domain UA74_RS26860 2d5b6e797ee658e56d6abb9b5f7d2597 376 Pfam PF13439 Glycosyltransferase Family 4 13 173 1.2E-20 T 09-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_RS26860 2d5b6e797ee658e56d6abb9b5f7d2597 376 Gene3D G3DSA:3.40.50.2000 161 346 3.3E-19 T 09-03-2017 UA74_RS26860 2d5b6e797ee658e56d6abb9b5f7d2597 376 Pfam PF00534 Glycosyl transferases group 1 192 347 2.2E-20 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS26860 2d5b6e797ee658e56d6abb9b5f7d2597 376 SUPERFAMILY SSF53756 8 368 4.71E-68 T 09-03-2017 UA74_RS15165 6e72fde1d43cbaec0dda7f922129cca4 195 SUPERFAMILY SSF48498 129 164 9.93E-6 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS15165 6e72fde1d43cbaec0dda7f922129cca4 195 SUPERFAMILY SSF46689 10 76 1.05E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15165 6e72fde1d43cbaec0dda7f922129cca4 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 2.3E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS15165 6e72fde1d43cbaec0dda7f922129cca4 195 Gene3D G3DSA:1.10.357.10 7 192 4.3E-24 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS27775 74b446a96f7b3843d45566d007120a61 196 SUPERFAMILY SSF55729 1 149 2.84E-19 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS27775 74b446a96f7b3843d45566d007120a61 196 Pfam PF13673 Acetyltransferase (GNAT) domain 41 149 1.5E-9 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS27775 74b446a96f7b3843d45566d007120a61 196 Gene3D G3DSA:3.40.630.30 1 139 1.1E-17 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS24885 89f3c67f4ddb40b169114a9ea371cd75 458 SUPERFAMILY SSF51569 11 457 6.96E-190 T 09-03-2017 UA74_RS24885 89f3c67f4ddb40b169114a9ea371cd75 458 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 27 457 4.1E-212 T 09-03-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_RS24885 89f3c67f4ddb40b169114a9ea371cd75 458 Pfam PF01474 Class-II DAHP synthetase family 31 453 2.5E-186 T 09-03-2017 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_RS02605 cdd3227496bb86b5009b7fe984a7c0cf 541 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 15 531 17.454 T 09-03-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 UA74_RS02605 cdd3227496bb86b5009b7fe984a7c0cf 541 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 163 529 6.2E-113 T 09-03-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 UA74_RS02605 cdd3227496bb86b5009b7fe984a7c0cf 541 Pfam PF00361 Proton-conducting membrane transporter 183 476 1.2E-75 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS12100 e605c3c5e2a03abca7b2dec13a5d96cb 599 Pfam PF04183 IucA / IucC family 140 387 4.6E-73 T 09-03-2017 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 UA74_RS12100 e605c3c5e2a03abca7b2dec13a5d96cb 599 Pfam PF06276 Ferric iron reductase FhuF-like transporter 409 560 3.3E-31 T 09-03-2017 IPR022770 Ferric iron reductase FhuF domain UA74_RS26955 f5fc74bded1974fda8802fafa9ffac80 436 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 43 368 3.3E-33 T 09-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_RS26955 f5fc74bded1974fda8802fafa9ffac80 436 Gene3D G3DSA:3.40.50.300 193 369 2.2E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26955 f5fc74bded1974fda8802fafa9ffac80 436 Gene3D G3DSA:3.40.50.300 4 129 2.2E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26955 f5fc74bded1974fda8802fafa9ffac80 436 SUPERFAMILY SSF52540 43 146 2.15E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS26955 f5fc74bded1974fda8802fafa9ffac80 436 SUPERFAMILY SSF52540 204 372 2.15E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS00605 7b6500cd3b38bc3d289dcb9a692e0838 156 Pfam PF03994 Domain of Unknown Function (DUF350) 101 155 1.8E-9 T 09-03-2017 IPR007140 Protein of unknown function DUF350 UA74_RS00605 7b6500cd3b38bc3d289dcb9a692e0838 156 Pfam PF03994 Domain of Unknown Function (DUF350) 31 84 1.1E-14 T 09-03-2017 IPR007140 Protein of unknown function DUF350 UA74_RS22655 2c539fc60f8d88b78738601f4219c019 122 SUPERFAMILY SSF53223 10 82 6.91E-11 T 09-03-2017 UA74_RS22655 2c539fc60f8d88b78738601f4219c019 122 Gene3D G3DSA:3.40.192.10 10 82 1.8E-14 T 09-03-2017 UA74_RS22655 2c539fc60f8d88b78738601f4219c019 122 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 79 2.4E-10 T 09-03-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UA74_RS12055 7a5cc4cd6d7914774034b1d81dd5c1b8 169 Gene3D G3DSA:1.10.10.10 3 150 1.1E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12055 7a5cc4cd6d7914774034b1d81dd5c1b8 169 SUPERFAMILY SSF46785 5 148 7.65E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS12055 7a5cc4cd6d7914774034b1d81dd5c1b8 169 SMART SM00347 32 135 3.0E-10 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS12055 7a5cc4cd6d7914774034b1d81dd5c1b8 169 Pfam PF01047 MarR family 47 97 8.8E-11 T 09-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_RS07495 df994854cfbe98ae453ea6676e23aa47 169 Gene3D G3DSA:3.30.530.20 15 167 1.3E-31 T 09-03-2017 IPR023393 START-like domain UA74_RS07495 df994854cfbe98ae453ea6676e23aa47 169 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 30 146 7.3E-15 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS07495 df994854cfbe98ae453ea6676e23aa47 169 SUPERFAMILY SSF55961 16 167 4.66E-31 T 09-03-2017 UA74_RS01555 e9092a38837c4f42debfab30ae61c89c 609 Pfam PF13367 Protease prsW family 54 249 1.6E-51 T 09-03-2017 IPR026898 Protease PrsW GO:0008233 UA74_RS22170 e0180a6a4e69effaca27111e9869728e 567 SUPERFAMILY SSF89372 360 544 5.89E-14 T 09-03-2017 UA74_RS22170 e0180a6a4e69effaca27111e9869728e 567 SUPERFAMILY SSF89372 203 396 1.96E-12 T 09-03-2017 UA74_RS22170 e0180a6a4e69effaca27111e9869728e 567 Gene3D G3DSA:2.130.10.10 264 541 3.2E-4 T 09-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 UA74_RS20690 40ca7201ccccfaee74ed6393f8d19e41 409 SUPERFAMILY SSF53850 8 407 4.4E-59 T 09-03-2017 UA74_RS20690 40ca7201ccccfaee74ed6393f8d19e41 409 Pfam PF13416 Bacterial extracellular solute-binding protein 39 335 6.0E-27 T 09-03-2017 UA74_RS20690 40ca7201ccccfaee74ed6393f8d19e41 409 Gene3D G3DSA:3.40.190.10 11 133 2.3E-33 T 09-03-2017 UA74_RS20690 40ca7201ccccfaee74ed6393f8d19e41 409 Gene3D G3DSA:3.40.190.10 303 354 2.3E-33 T 09-03-2017 UA74_RS20690 40ca7201ccccfaee74ed6393f8d19e41 409 Gene3D G3DSA:3.40.190.10 152 302 8.2E-15 T 09-03-2017 UA74_RS12385 754e445e76787bb787e619e192d6aadd 366 Gene3D G3DSA:3.20.20.330 10 100 1.6E-79 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS12385 754e445e76787bb787e619e192d6aadd 366 Gene3D G3DSA:3.20.20.330 170 364 1.6E-79 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS12385 754e445e76787bb787e619e192d6aadd 366 Pfam PF02574 Homocysteine S-methyltransferase 13 361 3.0E-63 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS12385 754e445e76787bb787e619e192d6aadd 366 SUPERFAMILY SSF82282 165 364 1.08E-67 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS12385 754e445e76787bb787e619e192d6aadd 366 SUPERFAMILY SSF82282 9 99 1.08E-67 T 09-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_RS18140 d98f8fa77fbf1a69d1fa788d4caf4ca5 286 Pfam PF03537 Glycoside-hydrolase family GH114 45 270 6.8E-39 T 09-03-2017 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain UA74_RS18140 d98f8fa77fbf1a69d1fa788d4caf4ca5 286 SUPERFAMILY SSF51445 57 256 2.74E-16 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS07585 8da895e42f754ac3d7c3ad5a5c2db609 192 SUPERFAMILY SSF48498 87 191 6.07E-14 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS07585 8da895e42f754ac3d7c3ad5a5c2db609 192 Gene3D G3DSA:1.10.357.10 11 191 1.5E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS07585 8da895e42f754ac3d7c3ad5a5c2db609 192 SUPERFAMILY SSF46689 12 84 7.48E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS07585 8da895e42f754ac3d7c3ad5a5c2db609 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 2.2E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS11970 e462540ffcc8e230a60affce657b104a 199 Gene3D G3DSA:3.40.50.850 2 193 1.4E-46 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS11970 e462540ffcc8e230a60affce657b104a 199 SUPERFAMILY SSF52499 2 193 3.92E-39 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS11970 e462540ffcc8e230a60affce657b104a 199 Pfam PF00857 Isochorismatase family 4 145 2.3E-32 T 09-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 UA74_RS20505 532240eacf27c68e4b52d14772450707 235 Pfam PF11139 Sap, sulfolipid-1-addressing protein 9 229 4.2E-31 T 09-03-2017 IPR021315 Glycolipid exporter Gap/Sap UA74_RS02545 9ff2f57cf56124b977bc85efd1e1deaf 183 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 09-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02545 9ff2f57cf56124b977bc85efd1e1deaf 183 SUPERFAMILY SSF56770 9 153 1.7E-66 T 09-03-2017 UA74_RS02545 9ff2f57cf56124b977bc85efd1e1deaf 183 Gene3D G3DSA:3.40.50.700 21 151 4.1E-35 T 09-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02545 9ff2f57cf56124b977bc85efd1e1deaf 183 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 43.144 T 09-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02545 9ff2f57cf56124b977bc85efd1e1deaf 183 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 2.2E-70 T 09-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02545 9ff2f57cf56124b977bc85efd1e1deaf 183 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 4.0E-25 T 09-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS19250 03001caefd22686f6b020fdb9e52b472 85 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 29 80 1.0E-9 T 09-03-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 UA74_RS24485 28454bb6ece01fdf719ef26c046aed96 245 SUPERFAMILY SSF52317 35 212 1.05E-18 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS24485 28454bb6ece01fdf719ef26c046aed96 245 Gene3D G3DSA:3.40.50.880 26 232 3.5E-36 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS24485 28454bb6ece01fdf719ef26c046aed96 245 Pfam PF03575 Peptidase family S51 36 209 4.3E-25 T 09-03-2017 IPR005320 Peptidase S51 GO:0006508|GO:0008236 UA74_RS18285 8ebdef9f4d7d3275bd190cc4c24a67bb 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 321 2.0E-41 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS23910 4ac0b04e337e45150a463434c74d0df5 602 Pfam PF04616 Glycosyl hydrolases family 43 63 336 3.6E-68 T 09-03-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_RS23910 4ac0b04e337e45150a463434c74d0df5 602 Gene3D G3DSA:2.60.120.200 379 569 9.2E-28 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS23910 4ac0b04e337e45150a463434c74d0df5 602 SUPERFAMILY SSF75005 63 341 1.57E-75 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS23910 4ac0b04e337e45150a463434c74d0df5 602 Gene3D G3DSA:2.115.10.20 62 341 3.0E-69 T 09-03-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain UA74_RS23910 4ac0b04e337e45150a463434c74d0df5 602 SUPERFAMILY SSF49899 379 569 9.89E-25 T 09-03-2017 IPR013320 Concanavalin A-like lectin/glucanase domain UA74_RS14710 c706bc421f5d229839614f357bfc66ba 416 Pfam PF01554 MatE 213 367 5.0E-10 T 09-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_RS27660 a5e5ab25475c35c0d604c225bd91fcf7 430 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 355 1.1E-35 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS23630 bb43e96799848a6ed4d4ccd59e506d4f 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 111 178 1.2E-10 T 09-03-2017 IPR009597 Domain of unknown function DUF1206 UA74_RS23630 bb43e96799848a6ed4d4ccd59e506d4f 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 26 92 3.0E-19 T 09-03-2017 IPR009597 Domain of unknown function DUF1206 UA74_RS23630 bb43e96799848a6ed4d4ccd59e506d4f 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 203 270 9.5E-16 T 09-03-2017 IPR009597 Domain of unknown function DUF1206 UA74_RS14635 ade2b4522623cbbceddf76c0f6ed146b 206 Gene3D G3DSA:3.40.50.1820 6 204 3.2E-62 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS14635 ade2b4522623cbbceddf76c0f6ed146b 206 Pfam PF02230 Phospholipase/Carboxylesterase 14 203 4.5E-13 T 09-03-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 UA74_RS14635 ade2b4522623cbbceddf76c0f6ed146b 206 SUPERFAMILY SSF53474 10 204 1.28E-48 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS12785 288a671b8de3c26cab4d9a364acb04e0 180 Gene3D G3DSA:2.40.33.20 2 177 9.5E-60 T 09-03-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like UA74_RS12785 288a671b8de3c26cab4d9a364acb04e0 180 Pfam PF03473 MOSC domain 57 166 3.2E-5 T 09-03-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 UA74_RS12785 288a671b8de3c26cab4d9a364acb04e0 180 SUPERFAMILY SSF50800 2 169 3.19E-39 T 09-03-2017 IPR011037 Pyruvate kinase-like, insert domain UA74_RS02020 b1707082ea948ee81dae58247bd73155 95 Pfam PF10724 Protein of unknown function (DUF2516) 3 92 2.0E-29 T 09-03-2017 IPR019662 Protein of unknown function DUF2516 UA74_RS04280 7ce7b069c7e663f9663f7ea4e4e6d2c4 654 Pfam PF02687 FtsX-like permease family 531 645 4.9E-14 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS04280 7ce7b069c7e663f9663f7ea4e4e6d2c4 654 Pfam PF02687 FtsX-like permease family 69 187 1.5E-12 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS00635 79a331bfa79ee45a1d399cb9bc591154 122 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 2 106 1.9E-23 T 09-03-2017 IPR019277 Protein of unknown function DUF2304 UA74_RS10105 1257d0a1a465dcc602c009607615a9e9 204 SUPERFAMILY SSF48498 89 195 1.38E-22 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS10105 1257d0a1a465dcc602c009607615a9e9 204 SUPERFAMILY SSF46689 9 75 9.23E-17 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS10105 1257d0a1a465dcc602c009607615a9e9 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 9.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS10105 1257d0a1a465dcc602c009607615a9e9 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.4E-8 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS10105 1257d0a1a465dcc602c009607615a9e9 204 Gene3D G3DSA:1.10.10.60 8 67 5.2E-20 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS10105 1257d0a1a465dcc602c009607615a9e9 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.2E-14 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS10105 1257d0a1a465dcc602c009607615a9e9 204 Gene3D G3DSA:1.10.357.10 70 196 2.1E-35 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 259 475 4.7E-43 T 09-03-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 225 6.0E-29 T 09-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 Gene3D G3DSA:3.40.50.300 4 238 7.4E-46 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 523 3.1E-142 T 09-03-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 Gene3D G3DSA:3.40.50.880 258 413 1.8E-37 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 Gene3D G3DSA:3.40.50.880 451 482 1.8E-37 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 SUPERFAMILY SSF52540 4 239 7.71E-55 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 532 178.62 T 09-03-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 SUPERFAMILY SSF52317 192 238 2.08E-36 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS09135 8dca1c14a9b5be764dce9f4a9e369b85 546 SUPERFAMILY SSF52317 271 398 2.08E-36 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS27335 7c584a4f1db2e030292920c7bdd601f8 365 Pfam PF07730 Histidine kinase 184 247 1.8E-15 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS27335 7c584a4f1db2e030292920c7bdd601f8 365 SUPERFAMILY SSF55874 251 364 1.92E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS05955 3fab9c4f49766ca1998100a584bed50a 93 Pfam PF02583 Metal-sensitive transcriptional repressor 8 88 8.1E-31 T 09-03-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 UA74_RS12720 822ae1f42a1d2a6d675f9da0b186466f 268 Gene3D G3DSA:3.90.226.10 16 248 4.7E-57 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS12720 822ae1f42a1d2a6d675f9da0b186466f 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 251 8.5E-33 T 09-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 UA74_RS12720 822ae1f42a1d2a6d675f9da0b186466f 268 SUPERFAMILY SSF52096 16 257 2.7E-57 T 09-03-2017 IPR029045 ClpP/crotonase-like domain UA74_RS12720 822ae1f42a1d2a6d675f9da0b186466f 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 122 142 - T 09-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 UA74_RS01370 cba8a9a59220cdf198fba3c5f908dabe 142 Pfam PF00482 Type II secretion system (T2SS), protein F 7 124 2.0E-14 T 09-03-2017 IPR018076 Type II secretion system F domain UA74_RS06255 89258e5eea7200a1eb444bd84bb7737f 259 Gene3D G3DSA:3.30.460.10 33 80 5.8E-4 T 09-03-2017 UA74_RS12690 90aadfb082645f30cc665412f87b7fd7 241 Pfam PF13649 Methyltransferase domain 34 126 4.1E-14 T 09-03-2017 UA74_RS12690 90aadfb082645f30cc665412f87b7fd7 241 SUPERFAMILY SSF53335 25 237 1.61E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12690 90aadfb082645f30cc665412f87b7fd7 241 Gene3D G3DSA:3.40.50.150 30 154 7.5E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS12690 90aadfb082645f30cc665412f87b7fd7 241 Gene3D G3DSA:3.40.50.150 191 220 7.5E-28 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS30195 cbcc1526fa770d8790fac02d9e0f1c89 281 Pfam PF13349 Putative adhesin 20 278 6.7E-14 T 09-03-2017 IPR025164 Putative adhesin UA74_RS03425 3d13426ff3bc0638b8563c78705d84a3 434 SUPERFAMILY SSF56322 59 433 7.85E-93 T 09-03-2017 IPR005801 ADC synthase GO:0009058 UA74_RS03425 3d13426ff3bc0638b8563c78705d84a3 434 Gene3D G3DSA:3.60.120.10 97 432 6.2E-103 T 09-03-2017 IPR005801 ADC synthase GO:0009058 UA74_RS03425 3d13426ff3bc0638b8563c78705d84a3 434 Pfam PF00425 chorismate binding enzyme 169 424 3.5E-75 T 09-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal UA74_RS03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 377 391 3.1E-10 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 268 281 3.1E-10 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 362 376 3.1E-10 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 282 295 3.1E-10 T 09-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_RS02865 8e5e58e0333bb32f99ef52fe88cc9527 74 Pfam PF04149 Domain of unknown function (DUF397) 13 68 3.0E-14 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS26215 1bd3d099423c0d984b14002bbcfe7867 207 Gene3D G3DSA:1.10.357.10 10 199 1.1E-28 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS26215 1bd3d099423c0d984b14002bbcfe7867 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 5.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS26215 1bd3d099423c0d984b14002bbcfe7867 207 SUPERFAMILY SSF48498 91 192 6.16E-10 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS26215 1bd3d099423c0d984b14002bbcfe7867 207 SUPERFAMILY SSF46689 9 91 9.22E-13 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS14155 7b6f776d0d7e138a3343ff4fcdcbc348 192 SUPERFAMILY SSF54427 41 152 2.93E-11 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS14155 7b6f776d0d7e138a3343ff4fcdcbc348 192 Pfam PF12680 SnoaL-like domain 42 143 6.0E-8 T 09-03-2017 IPR009959 Polyketide cyclase SnoaL-like domain UA74_RS14155 7b6f776d0d7e138a3343ff4fcdcbc348 192 Gene3D G3DSA:3.10.450.50 37 152 1.9E-19 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS17415 64e8f46e493415ef0f140814b382a064 609 Gene3D G3DSA:3.40.50.720 366 378 5.5E-4 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17415 64e8f46e493415ef0f140814b382a064 609 Gene3D G3DSA:3.40.50.720 254 283 5.5E-4 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17415 64e8f46e493415ef0f140814b382a064 609 SUPERFAMILY SSF51905 76 303 4.53E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17415 64e8f46e493415ef0f140814b382a064 609 SUPERFAMILY SSF51905 403 529 4.53E-44 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17415 64e8f46e493415ef0f140814b382a064 609 Gene3D G3DSA:3.50.50.60 67 253 1.7E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17415 64e8f46e493415ef0f140814b382a064 609 Gene3D G3DSA:3.50.50.60 493 582 1.7E-62 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17415 64e8f46e493415ef0f140814b382a064 609 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 75 268 9.1E-10 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS25065 63401f5dec38df8f16208c949ee4dc07 136 Gene3D G3DSA:3.40.50.2300 7 130 3.4E-8 T 09-03-2017 UA74_RS25065 63401f5dec38df8f16208c949ee4dc07 136 SUPERFAMILY SSF52172 37 130 2.42E-6 T 09-03-2017 IPR011006 CheY-like superfamily UA74_RS14820 13c7d4fa10eac6b37bf9354c13467af1 115 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 112 25.124 T 09-03-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_RS14820 13c7d4fa10eac6b37bf9354c13467af1 115 Pfam PF13397 RNA polymerase-binding protein 4 107 1.8E-42 T 09-03-2017 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_RS23110 ac1c4983beb6a6b179fe97d6ba18bd77 62 Pfam PF04149 Domain of unknown function (DUF397) 8 60 1.1E-20 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 9.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 9.5E-11 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.7E-24 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 Pfam PF00106 short chain dehydrogenase 17 201 8.9E-50 T 09-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 197 0.0023 T 09-03-2017 UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 SUPERFAMILY SSF51735 15 249 3.47E-63 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 09-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_RS07655 eff3802c6be0b1d29536d64be1bca98d 290 Gene3D G3DSA:3.40.50.720 16 255 3.4E-67 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS13885 1871614a56c73ef8920f32e40320a04e 222 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 17 208 1.2E-29 T 09-03-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_RS13885 1871614a56c73ef8920f32e40320a04e 222 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 17 211 3.1E-41 T 09-03-2017 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 UA74_RS13885 1871614a56c73ef8920f32e40320a04e 222 PIRSF PIRSF029950 9 218 1.8E-61 T 09-03-2017 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 UA74_RS13885 1871614a56c73ef8920f32e40320a04e 222 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 17 56 2.2E-14 T 09-03-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_RS16800 ebc08c8f49fee2f67ca8d22200fb5d12 233 SUPERFAMILY SSF140453 89 170 2.22E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS16800 ebc08c8f49fee2f67ca8d22200fb5d12 233 Gene3D G3DSA:1.10.287.1060 90 169 4.2E-6 T 09-03-2017 UA74_RS09225 6fd4e877606cba083bc733bb32fe3bfe 159 SUPERFAMILY SSF55729 20 154 1.01E-27 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09225 6fd4e877606cba083bc733bb32fe3bfe 159 Gene3D G3DSA:3.40.630.30 19 153 4.2E-36 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS09225 6fd4e877606cba083bc733bb32fe3bfe 159 Pfam PF13673 Acetyltransferase (GNAT) domain 68 153 1.5E-14 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS10590 0a4176eebd033966e4bb6b5072067ac0 153 PRINTS PR01438 Universal stress protein signature 5 23 1.6E-10 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS10590 0a4176eebd033966e4bb6b5072067ac0 153 PRINTS PR01438 Universal stress protein signature 118 140 1.6E-10 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS10590 0a4176eebd033966e4bb6b5072067ac0 153 PRINTS PR01438 Universal stress protein signature 100 112 1.6E-10 T 09-03-2017 IPR006015 Universal stress protein A UA74_RS10590 0a4176eebd033966e4bb6b5072067ac0 153 Gene3D G3DSA:3.40.50.620 3 143 1.1E-31 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS10590 0a4176eebd033966e4bb6b5072067ac0 153 Pfam PF00582 Universal stress protein family 4 140 1.1E-23 T 09-03-2017 IPR006016 UspA GO:0006950 UA74_RS10590 0a4176eebd033966e4bb6b5072067ac0 153 SUPERFAMILY SSF52402 7 143 8.37E-30 T 09-03-2017 UA74_RS27750 d0005ab91978837d0be1041f8be03873 267 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 247 4.3E-32 T 09-03-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase UA74_RS05150 747d953afc1a0aebae2375b81a0ae638 382 SUPERFAMILY SSF53756 21 372 1.26E-26 T 09-03-2017 UA74_RS05150 747d953afc1a0aebae2375b81a0ae638 382 Pfam PF13692 Glycosyl transferases group 1 204 336 5.0E-11 T 09-03-2017 UA74_RS12085 b757c7fd526bef520acb69951ed53277 120 SUPERFAMILY SSF51182 3 112 1.07E-22 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS12085 b757c7fd526bef520acb69951ed53277 120 Pfam PF07883 Cupin domain 39 96 3.6E-11 T 09-03-2017 IPR013096 Cupin 2, conserved barrel UA74_RS12085 b757c7fd526bef520acb69951ed53277 120 Gene3D G3DSA:2.60.120.10 3 106 1.5E-32 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS12405 46842fe0f26b7a81bd6a64a2820af3e3 164 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 150 8.9E-38 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12405 46842fe0f26b7a81bd6a64a2820af3e3 164 Gene3D G3DSA:3.40.50.960 11 156 9.0E-54 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12405 46842fe0f26b7a81bd6a64a2820af3e3 164 SUPERFAMILY SSF52121 13 157 1.44E-49 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12405 46842fe0f26b7a81bd6a64a2820af3e3 164 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 26.005 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS12405 46842fe0f26b7a81bd6a64a2820af3e3 164 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 16 152 1.1E-47 T 09-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_RS13325 b67abf6a1c63ca6b5ef2880082dd42e4 339 Gene3D G3DSA:3.40.50.1980 178 330 1.0E-18 T 09-03-2017 UA74_RS13325 b67abf6a1c63ca6b5ef2880082dd42e4 339 Gene3D G3DSA:3.40.50.1980 51 177 2.6E-23 T 09-03-2017 UA74_RS13325 b67abf6a1c63ca6b5ef2880082dd42e4 339 SUPERFAMILY SSF53807 49 313 1.14E-46 T 09-03-2017 UA74_RS13325 b67abf6a1c63ca6b5ef2880082dd42e4 339 Pfam PF01497 Periplasmic binding protein 71 295 1.1E-15 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS24500 fea657a0c38a004e35d7b995773e9cf5 132 Gene3D G3DSA:3.30.70.900 2 77 3.2E-6 T 09-03-2017 UA74_RS24500 fea657a0c38a004e35d7b995773e9cf5 132 SUPERFAMILY SSF54909 4 68 3.09E-7 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS24225 05ea196830066b19d22677bffe46f767 273 Pfam PF03073 TspO/MBR family 29 176 2.8E-5 T 09-03-2017 IPR004307 TspO/MBR-related protein GO:0016021 UA74_RS14280 9fe87322ae81ec5642a30907a3bf68ca 204 Gene3D G3DSA:1.10.10.10 20 83 2.1E-7 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14280 9fe87322ae81ec5642a30907a3bf68ca 204 SUPERFAMILY SSF46785 23 119 3.74E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14280 9fe87322ae81ec5642a30907a3bf68ca 204 Pfam PF13412 Winged helix-turn-helix DNA-binding 29 69 5.3E-5 T 09-03-2017 UA74_RS01720 4bfdc56d515bc4f8df1848bf60332341 209 SUPERFAMILY SSF53335 6 194 8.21E-30 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS01720 4bfdc56d515bc4f8df1848bf60332341 209 Pfam PF13649 Methyltransferase domain 44 138 6.4E-18 T 09-03-2017 UA74_RS01720 4bfdc56d515bc4f8df1848bf60332341 209 Gene3D G3DSA:3.40.50.150 6 186 1.6E-29 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS13790 6f190eb0c70c742d848b0cd724d6f151 118 Pfam PF05331 Protein of unknown function (DUF742) 7 116 1.5E-29 T 09-03-2017 IPR007995 Protein of unknown function DUF742 UA74_RS04710 487b356ddff6c21d74c53dd82fb66b6c 371 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 10 368 2.4E-91 T 09-03-2017 IPR011200 Uncharacterised conserved protein UCP012608 UA74_RS15430 c93b9e0ceda83dfafbc22e5db39c6a07 196 Gene3D G3DSA:1.10.357.10 6 191 6.0E-27 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS15430 c93b9e0ceda83dfafbc22e5db39c6a07 196 SUPERFAMILY SSF46689 2 68 4.99E-12 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS15430 c93b9e0ceda83dfafbc22e5db39c6a07 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 6.8E-6 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS04535 70a491944642053a4b8280c831c64ce1 195 Pfam PF12079 Protein of unknown function (DUF3558) 19 186 3.9E-18 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS23430 f000a5a8ff3a6c027ecd709272cd4133 378 SUPERFAMILY SSF53335 149 308 8.68E-15 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS04515 3b5d9968ec96d18813cadafe4ff1270f 96 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 51 80 4.1E-10 T 09-03-2017 IPR019933 DivIVA domain UA74_RS22725 8cf23fcc5787885873874cad405e4080 504 Gene3D G3DSA:3.90.76.10 36 191 7.4E-30 T 09-03-2017 UA74_RS22725 8cf23fcc5787885873874cad405e4080 504 SUPERFAMILY SSF53850 24 492 2.53E-89 T 09-03-2017 UA74_RS22725 8cf23fcc5787885873874cad405e4080 504 Gene3D G3DSA:3.10.105.10 257 450 4.1E-30 T 09-03-2017 UA74_RS22725 8cf23fcc5787885873874cad405e4080 504 PIRSF PIRSF002741 1 501 3.4E-62 T 09-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_RS22725 8cf23fcc5787885873874cad405e4080 504 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 384 5.0E-65 T 09-03-2017 IPR000914 Solute-binding protein family 5 domain UA74_RS21975 343c55ca444ebca501f1ed52ab86def5 128 Gene3D G3DSA:1.10.357.10 4 98 0.001 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS23390 a92c9da9e5bf577a94184a510672fa3e 258 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 1 204 5.0E-38 T 09-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_RS01860 648533e15d72273a651892b5153ac376 98 Pfam PF11662 Protein of unknown function (DUF3263) 16 88 2.5E-33 T 09-03-2017 IPR021678 Protein of unknown function DUF3263 UA74_RS13145 1d260bd9a543f9bf9b80ec8a5dce954c 229 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 30 211 9.1E-18 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS13145 1d260bd9a543f9bf9b80ec8a5dce954c 229 Gene3D G3DSA:3.40.50.1110 18 221 4.2E-35 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS13145 1d260bd9a543f9bf9b80ec8a5dce954c 229 SUPERFAMILY SSF52266 18 221 5.07E-35 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS08685 ec6fdb58ef64eb7953cfa76cc8bdb33c 251 Gene3D G3DSA:3.40.50.300 9 245 3.0E-84 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08685 ec6fdb58ef64eb7953cfa76cc8bdb33c 251 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS08685 ec6fdb58ef64eb7953cfa76cc8bdb33c 251 PIRSF PIRSF039085 7 250 4.4E-112 T 09-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UA74_RS08685 ec6fdb58ef64eb7953cfa76cc8bdb33c 251 SUPERFAMILY SSF52540 10 244 5.45E-81 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08685 ec6fdb58ef64eb7953cfa76cc8bdb33c 251 SMART SM00382 35 222 5.6E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS08685 ec6fdb58ef64eb7953cfa76cc8bdb33c 251 Pfam PF00005 ABC transporter 26 174 5.0E-36 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS25915 bce50a6d6f2e181832adf4db49af0eb7 206 SUPERFAMILY SSF46689 8 79 1.13E-6 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS25915 bce50a6d6f2e181832adf4db49af0eb7 206 SUPERFAMILY SSF48498 80 167 1.75E-15 T 09-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_RS25915 bce50a6d6f2e181832adf4db49af0eb7 206 Pfam PF13305 WHG domain 85 165 2.5E-13 T 09-03-2017 IPR025996 WHG domain UA74_RS25915 bce50a6d6f2e181832adf4db49af0eb7 206 Gene3D G3DSA:1.10.357.10 27 167 2.0E-26 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS06745 d243deb9dbaf7f5b3d6dc0934a4f0e1a 413 SUPERFAMILY SSF141523 256 380 4.19E-27 T 09-03-2017 UA74_RS06745 d243deb9dbaf7f5b3d6dc0934a4f0e1a 413 Gene3D G3DSA:2.40.440.10 264 380 4.1E-18 T 09-03-2017 UA74_RS06745 d243deb9dbaf7f5b3d6dc0934a4f0e1a 413 Pfam PF03734 L,D-transpeptidase catalytic domain 265 380 7.4E-16 T 09-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UA74_RS10120 a3f91b908e098a16b16809e39d6e17c4 270 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 52 69 - T 09-03-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 UA74_RS10120 a3f91b908e098a16b16809e39d6e17c4 270 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 258 32.419 T 09-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 UA74_RS10120 a3f91b908e098a16b16809e39d6e17c4 270 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 256 8.4E-77 T 09-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 UA74_RS10120 a3f91b908e098a16b16809e39d6e17c4 270 SUPERFAMILY SSF51366 13 258 5.49E-76 T 09-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 UA74_RS10120 a3f91b908e098a16b16809e39d6e17c4 270 Gene3D G3DSA:3.20.20.70 3 260 2.5E-92 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS23640 2e4d248c6b7b30a4ca7c65d286fedbe5 370 Gene3D G3DSA:3.30.420.40 1 122 1.6E-22 T 09-03-2017 UA74_RS23640 2e4d248c6b7b30a4ca7c65d286fedbe5 370 Gene3D G3DSA:3.30.420.150 125 304 4.2E-35 T 09-03-2017 UA74_RS23640 2e4d248c6b7b30a4ca7c65d286fedbe5 370 SUPERFAMILY SSF53067 3 125 5.89E-20 T 09-03-2017 UA74_RS23640 2e4d248c6b7b30a4ca7c65d286fedbe5 370 SUPERFAMILY SSF53067 132 303 4.53E-28 T 09-03-2017 UA74_RS23640 2e4d248c6b7b30a4ca7c65d286fedbe5 370 Pfam PF02541 Ppx/GppA phosphatase family 33 303 2.3E-49 T 09-03-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 UA74_RS21890 0824f346371e50de383889ca7a96530b 101 Gene3D G3DSA:1.10.1200.10 13 98 3.0E-7 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS21890 0824f346371e50de383889ca7a96530b 101 SUPERFAMILY SSF47336 13 99 4.89E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS22895 8accf49ff85bb31d83266e31bcae1c6a 287 Pfam PF13560 Helix-turn-helix domain 20 80 1.3E-10 T 09-03-2017 UA74_RS22895 8accf49ff85bb31d83266e31bcae1c6a 287 SUPERFAMILY SSF47413 12 76 4.93E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22895 8accf49ff85bb31d83266e31bcae1c6a 287 Gene3D G3DSA:1.10.260.40 14 76 2.6E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS10960 2d71390f60bf3621179dbbafc2241a79 126 Pfam PF04486 SchA/CurD like domain 1 119 4.5E-49 T 09-03-2017 IPR007575 SchA/CurD-like domain UA74_RS07575 9ed8c1aec270326d32246fdedc19459c 305 Gene3D G3DSA:3.40.50.1820 58 299 1.4E-29 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07575 9ed8c1aec270326d32246fdedc19459c 305 SUPERFAMILY SSF53474 57 299 2.79E-32 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS07575 9ed8c1aec270326d32246fdedc19459c 305 Pfam PF00561 alpha/beta hydrolase fold 79 189 9.3E-14 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS18765 e7aae6872ed6e43b438e328cd0a10df1 149 SUPERFAMILY SSF50475 29 145 1.91E-5 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS18765 e7aae6872ed6e43b438e328cd0a10df1 149 Pfam PF04075 Domain of unknown function (DUF385) 14 141 1.0E-32 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS18765 e7aae6872ed6e43b438e328cd0a10df1 149 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 30 141 1.9E-27 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS18765 e7aae6872ed6e43b438e328cd0a10df1 149 Gene3D G3DSA:2.30.110.10 28 144 5.7E-5 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS10800 74cf5c53dd005fe32a984efbfd0cbba0 177 Gene3D G3DSA:3.40.630.30 1 173 9.6E-40 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS10800 74cf5c53dd005fe32a984efbfd0cbba0 177 SUPERFAMILY SSF55729 4 175 1.1E-25 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS10800 74cf5c53dd005fe32a984efbfd0cbba0 177 Pfam PF00583 Acetyltransferase (GNAT) family 67 149 1.8E-10 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS08505 26059c32fb5ff436c1777a0657b836d4 454 Pfam PF02653 Branched-chain amino acid transport system / permease component 138 438 2.6E-31 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS04950 a4712cf7dc483a0fa02ce78ec7e15fd6 167 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 2.6E-7 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS04950 a4712cf7dc483a0fa02ce78ec7e15fd6 167 Gene3D G3DSA:1.10.10.10 7 85 7.4E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04950 a4712cf7dc483a0fa02ce78ec7e15fd6 167 SUPERFAMILY SSF46785 8 159 4.95E-24 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01955 fdfa601dbd8bf79bdcc09398146fb37d 421 Pfam PF01547 Bacterial extracellular solute-binding protein 55 337 2.4E-41 T 09-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 UA74_RS01955 fdfa601dbd8bf79bdcc09398146fb37d 421 SUPERFAMILY SSF53850 19 419 1.2E-71 T 09-03-2017 UA74_RS01955 fdfa601dbd8bf79bdcc09398146fb37d 421 Gene3D G3DSA:3.40.190.10 34 159 1.1E-21 T 09-03-2017 UA74_RS01955 fdfa601dbd8bf79bdcc09398146fb37d 421 Gene3D G3DSA:3.40.190.10 160 347 1.3E-44 T 09-03-2017 UA74_RS07060 1f1c8a0b00c47876ca0ea284c588d3a6 309 Pfam PF11303 Protein of unknown function (DUF3105) 84 210 5.8E-41 T 09-03-2017 IPR021454 Protein of unknown function DUF3105 UA74_RS14775 37b98b324c66628d98f60b334ca5574d 211 Pfam PF01872 RibD C-terminal domain 4 191 7.8E-21 T 09-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_RS14775 37b98b324c66628d98f60b334ca5574d 211 SUPERFAMILY SSF53597 2 197 6.17E-25 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS14775 37b98b324c66628d98f60b334ca5574d 211 Gene3D G3DSA:3.40.430.10 3 197 6.9E-26 T 09-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 UA74_RS12270 90e8e3c611f260a65604d812a1803965 162 SMART SM00530 11 68 3.3E-7 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS12270 90e8e3c611f260a65604d812a1803965 162 SUPERFAMILY SSF47413 4 71 2.03E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS12270 90e8e3c611f260a65604d812a1803965 162 Pfam PF01381 Helix-turn-helix 12 68 7.2E-10 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS12270 90e8e3c611f260a65604d812a1803965 162 Gene3D G3DSA:1.10.260.40 3 73 8.6E-13 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS24130 90159e6b7b9550ff23ccad3917688a2f 424 SUPERFAMILY SSF140459 4 142 4.97E-6 T 09-03-2017 UA74_RS23170 b524142787c4f5e6f0f69b2a4f1e6bc5 211 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 43 178 5.4E-26 T 09-03-2017 IPR013382 CRISPR-associated protein Cse2 UA74_RS23170 b524142787c4f5e6f0f69b2a4f1e6bc5 211 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 42 178 2.6E-17 T 09-03-2017 IPR013382 CRISPR-associated protein Cse2 UA74_RS07865 a7ea69bdb9a5bddf85153bebeb0b1d0b 341 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 179 316 1.0E-6 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS07865 a7ea69bdb9a5bddf85153bebeb0b1d0b 341 Gene3D G3DSA:2.40.110.10 101 166 3.8E-8 T 09-03-2017 UA74_RS07865 a7ea69bdb9a5bddf85153bebeb0b1d0b 341 SUPERFAMILY SSF56645 23 179 1.55E-14 T 09-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 UA74_RS07865 a7ea69bdb9a5bddf85153bebeb0b1d0b 341 Gene3D G3DSA:1.20.140.10 167 317 1.9E-11 T 09-03-2017 UA74_RS07865 a7ea69bdb9a5bddf85153bebeb0b1d0b 341 SUPERFAMILY SSF47203 179 320 2.44E-9 T 09-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_RS09905 be610b12da3e1dd6d3392a9ffbb72345 161 Pfam PF10821 Protein of unknown function (DUF2567) 12 106 1.8E-9 T 09-03-2017 IPR021213 Protein of unknown function DUF2567 UA74_RS26905 07a8be1646f4cad0dfcd3ebb076e5a2b 519 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 215 384 1.3E-29 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS26905 07a8be1646f4cad0dfcd3ebb076e5a2b 519 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 215 383 1.3E-33 T 09-03-2017 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_RS01320 38e0e45a49628e1fb5d860cf78e1b235 194 Pfam PF12079 Protein of unknown function (DUF3558) 8 188 2.3E-22 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS16550 8a63eaa8c13c9e21b41268813fd48618 249 SMART SM00824 Thioesterase 24 247 8.7E-4 T 09-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_RS16550 8a63eaa8c13c9e21b41268813fd48618 249 Gene3D G3DSA:3.40.50.1820 14 247 2.5E-40 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16550 8a63eaa8c13c9e21b41268813fd48618 249 SUPERFAMILY SSF53474 9 245 1.31E-55 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS16550 8a63eaa8c13c9e21b41268813fd48618 249 Pfam PF00975 Thioesterase domain 22 244 1.0E-56 T 09-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_RS02705 d11715474e7248e51c6cca0628f9c1fd 612 SMART SM00332 6 245 1.6E-21 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS02705 d11715474e7248e51c6cca0628f9c1fd 612 Pfam PF13672 Protein phosphatase 2C 20 208 2.3E-12 T 09-03-2017 UA74_RS02705 d11715474e7248e51c6cca0628f9c1fd 612 SUPERFAMILY SSF81606 8 246 1.29E-59 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS02705 d11715474e7248e51c6cca0628f9c1fd 612 SMART SM00331 15 247 4.9E-27 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS02705 d11715474e7248e51c6cca0628f9c1fd 612 Gene3D G3DSA:3.60.40.10 9 247 1.9E-63 T 09-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 UA74_RS24480 5463f280befb5c61d655a039892ef6e0 218 Gene3D G3DSA:3.40.50.620 45 177 7.0E-16 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS24480 5463f280befb5c61d655a039892ef6e0 218 Pfam PF02698 DUF218 domain 52 198 9.2E-24 T 09-03-2017 IPR003848 Domain of unknown function DUF218 UA74_RS17445 a433ccf78fef9082b58eb704c8efa115 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 65 1.0E-7 T 09-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_RS17445 a433ccf78fef9082b58eb704c8efa115 217 Gene3D G3DSA:1.10.357.10 157 210 8.1E-27 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS17445 a433ccf78fef9082b58eb704c8efa115 217 Gene3D G3DSA:1.10.357.10 7 125 8.1E-27 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS17445 a433ccf78fef9082b58eb704c8efa115 217 SUPERFAMILY SSF46689 5 86 5.64E-14 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS23940 d720ed06769926919c8c580cd2640d1b 91 SMART SM00421 28 85 1.4E-6 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23940 d720ed06769926919c8c580cd2640d1b 91 Gene3D G3DSA:1.10.10.10 29 91 1.8E-14 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS23940 d720ed06769926919c8c580cd2640d1b 91 Pfam PF00196 Bacterial regulatory proteins, luxR family 30 85 2.1E-7 T 09-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_RS23940 d720ed06769926919c8c580cd2640d1b 91 SUPERFAMILY SSF46894 18 91 2.24E-14 T 09-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_RS29325 0c47207b54ae1fbebf5f95706ae69d11 211 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 47 210 34.195 T 09-03-2017 IPR022939 Uncharacterised protein family UPF0678 UA74_RS29325 0c47207b54ae1fbebf5f95706ae69d11 211 Pfam PF08768 Domain of unknown function (DUF1794) 56 208 4.6E-48 T 09-03-2017 IPR014878 Domain of unknown function DUF1794 UA74_RS29325 0c47207b54ae1fbebf5f95706ae69d11 211 SUPERFAMILY SSF50814 50 209 8.12E-41 T 09-03-2017 IPR011038 Calycin-like UA74_RS28500 5c0f3ed22d43cb39be169f4cc55deab1 76 Pfam PF10745 Protein of unknown function (DUF2530) 1 75 1.6E-22 T 09-03-2017 IPR019681 Protein of unknown function DUF2530 UA74_RS00965 3ce78946c9117758a2e0f52078e9ee7e 199 Pfam PF12079 Protein of unknown function (DUF3558) 22 196 2.8E-21 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS04525 9357767781318f0caff4f3e02fd7ee4c 262 Pfam PF14011 EspG family 14 254 6.4E-51 T 09-03-2017 IPR025734 EspG family UA74_RS14225 6afb9796d28ea372063ff4cb763f5f04 107 Pfam PF00893 Small Multidrug Resistance protein 2 93 4.2E-22 T 09-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 UA74_RS14225 6afb9796d28ea372063ff4cb763f5f04 107 SUPERFAMILY SSF103481 6 104 1.2E-13 T 09-03-2017 UA74_RS28270 36367aca44d822e0979a341d2260d172 392 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 2 390 3.6E-53 T 09-03-2017 IPR021368 Type VII secretion system protein EccE UA74_RS28270 36367aca44d822e0979a341d2260d172 392 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 198 300 8.8E-21 T 09-03-2017 IPR021368 Type VII secretion system protein EccE UA74_RS30035 3fbf9e080f8f7a7717d2f79f0fc33316 91 Pfam PF11755 Protein of unknown function (DUF3311) 20 70 3.4E-12 T 09-03-2017 IPR021741 Protein of unknown function DUF3311 UA74_RS26595 73179f38a1aca92cd0ef3860b4985d11 204 SUPERFAMILY SSF51182 2 196 8.9E-67 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS26595 73179f38a1aca92cd0ef3860b4985d11 204 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 9.0E-60 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_RS26595 73179f38a1aca92cd0ef3860b4985d11 204 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 6.7E-56 T 09-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_RS26595 73179f38a1aca92cd0ef3860b4985d11 204 Gene3D G3DSA:2.60.120.10 2 190 7.5E-64 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS08005 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 367 385 8.7E-6 T 09-03-2017 UA74_RS08005 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 229 240 8.7E-6 T 09-03-2017 UA74_RS08005 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 311 326 8.7E-6 T 09-03-2017 UA74_RS08005 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 336 346 8.7E-6 T 09-03-2017 UA74_RS13860 a3ef82f7b0a32dcb9d5b1f43015abb82 405 SUPERFAMILY SSF47413 5 64 2.25E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13860 a3ef82f7b0a32dcb9d5b1f43015abb82 405 SMART SM00530 13 68 1.9E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS13860 a3ef82f7b0a32dcb9d5b1f43015abb82 405 Gene3D G3DSA:1.10.260.40 4 64 1.6E-9 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS13860 a3ef82f7b0a32dcb9d5b1f43015abb82 405 Pfam PF13560 Helix-turn-helix domain 10 64 2.0E-11 T 09-03-2017 UA74_RS25270 ab6c6efe71f421567473d90ee0298e82 312 Pfam PF00520 Ion transport protein 14 224 4.5E-47 T 09-03-2017 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 UA74_RS25270 ab6c6efe71f421567473d90ee0298e82 312 SUPERFAMILY SSF81324 13 223 3.34E-39 T 09-03-2017 UA74_RS25270 ab6c6efe71f421567473d90ee0298e82 312 Gene3D G3DSA:1.20.120.350 4 111 2.4E-12 T 09-03-2017 IPR027359 Voltage-dependent channel, four helix bundle domain UA74_RS01725 86a411cb7abe43cd7fa433f51746b24d 439 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 153 306 4.4E-22 T 09-03-2017 IPR031811 AlgX, SGNH hydrolase-like domain UA74_RS28390 c737a46d5ab1d0454213f8d2d2e74103 388 Pfam PF12698 ABC-2 family transporter protein 15 364 2.7E-45 T 09-03-2017 UA74_RS03485 0b27a21d3b18d5ca7ac64ccbf0a5bbf8 278 SMART SM00530 12 68 3.3E-9 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS03485 0b27a21d3b18d5ca7ac64ccbf0a5bbf8 278 SUPERFAMILY SSF47413 10 68 1.75E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS03485 0b27a21d3b18d5ca7ac64ccbf0a5bbf8 278 Pfam PF13560 Helix-turn-helix domain 9 70 1.7E-10 T 09-03-2017 UA74_RS03485 0b27a21d3b18d5ca7ac64ccbf0a5bbf8 278 Gene3D G3DSA:1.10.260.40 4 63 5.6E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS19075 4be359732f19687b48e4f7e20a85f82f 628 Gene3D G3DSA:1.10.510.10 98 266 4.6E-38 T 09-03-2017 UA74_RS19075 4be359732f19687b48e4f7e20a85f82f 628 SUPERFAMILY SSF56112 12 269 2.43E-57 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS19075 4be359732f19687b48e4f7e20a85f82f 628 Pfam PF00069 Protein kinase domain 15 264 1.2E-33 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS19075 4be359732f19687b48e4f7e20a85f82f 628 Gene3D G3DSA:3.30.200.20 12 92 1.4E-11 T 09-03-2017 UA74_RS19075 4be359732f19687b48e4f7e20a85f82f 628 SMART SM00220 15 273 5.9E-35 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS19075 4be359732f19687b48e4f7e20a85f82f 628 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 09-03-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_RS19075 4be359732f19687b48e4f7e20a85f82f 628 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 09-03-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_RS00975 a05957770e60263098840337363ed9c6 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 297 8.9E-49 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS23995 0751d495f6033a95a8f5b675b58023e1 107 Gene3D G3DSA:3.30.1310.10 8 100 1.2E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS23995 0751d495f6033a95a8f5b675b58023e1 107 Pfam PF02575 YbaB/EbfC DNA-binding family 18 100 6.7E-10 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS23995 0751d495f6033a95a8f5b675b58023e1 107 SUPERFAMILY SSF82607 19 101 2.09E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS05170 9dc84e452dcdb07fb6c370c42925d650 133 SUPERFAMILY SSF54427 15 132 4.13E-9 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS05170 9dc84e452dcdb07fb6c370c42925d650 133 Gene3D G3DSA:3.10.450.50 17 119 1.7E-7 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS20930 2c9991fa94fc6eebe915539bb0dd1833 274 SUPERFAMILY SSF53335 32 206 5.14E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20930 2c9991fa94fc6eebe915539bb0dd1833 274 Gene3D G3DSA:3.40.50.150 32 204 1.6E-26 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS20930 2c9991fa94fc6eebe915539bb0dd1833 274 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 62 136 8.0E-8 T 09-03-2017 UA74_RS13295 70dbab951a075bb3d13088ee4747f655 855 Gene3D G3DSA:1.10.510.10 340 391 1.2E-8 T 09-03-2017 UA74_RS13295 70dbab951a075bb3d13088ee4747f655 855 Pfam PF01636 Phosphotransferase enzyme family 282 387 1.1E-6 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS13295 70dbab951a075bb3d13088ee4747f655 855 SUPERFAMILY SSF158745 514 843 7.85E-24 T 09-03-2017 UA74_RS13295 70dbab951a075bb3d13088ee4747f655 855 SMART SM00220 226 513 0.0024 T 09-03-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_RS13295 70dbab951a075bb3d13088ee4747f655 855 SMART SM01260 521 849 5.7E-9 T 09-03-2017 IPR007822 Lanthionine synthetase C-like UA74_RS13295 70dbab951a075bb3d13088ee4747f655 855 SUPERFAMILY SSF56112 225 428 9.98E-20 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS13435 58ca8cb8f13a5ac1fd22c7a75278f3d2 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 289 1.4E-41 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS25930 7478463ac6fd5be2695a00505887a1ed 225 SUPERFAMILY SSF55729 1 158 6.58E-25 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS25930 7478463ac6fd5be2695a00505887a1ed 225 Pfam PF00583 Acetyltransferase (GNAT) family 52 140 4.7E-12 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS25930 7478463ac6fd5be2695a00505887a1ed 225 Gene3D G3DSA:3.40.630.30 5 161 2.3E-24 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS17180 dcef9e052e5791b3c9cf9ed42a1d8691 553 SUPERFAMILY SSF51905 1 212 2.33E-9 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS17180 dcef9e052e5791b3c9cf9ed42a1d8691 553 Pfam PF13454 FAD-NAD(P)-binding 4 163 2.6E-34 T 09-03-2017 UA74_RS17180 dcef9e052e5791b3c9cf9ed42a1d8691 553 Gene3D G3DSA:3.50.50.60 1 163 5.1E-10 T 09-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_RS03320 dd6aeee70fa2bf19b2ba484247b71dbb 311 Gene3D G3DSA:3.20.20.100 3 305 2.6E-66 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS03320 dd6aeee70fa2bf19b2ba484247b71dbb 311 Pfam PF00248 Aldo/keto reductase family 15 302 5.3E-52 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS03320 dd6aeee70fa2bf19b2ba484247b71dbb 311 SUPERFAMILY SSF51430 2 305 6.81E-69 T 09-03-2017 IPR023210 NADP-dependent oxidoreductase domain UA74_RS06415 df3cdf7ffa21e30d508c1b3fcc906fc0 174 SUPERFAMILY SSF51182 26 158 3.96E-25 T 09-03-2017 IPR011051 RmlC-like cupin domain UA74_RS06415 df3cdf7ffa21e30d508c1b3fcc906fc0 174 Pfam PF05995 Cysteine dioxygenase type I 48 157 1.4E-18 T 09-03-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 UA74_RS06415 df3cdf7ffa21e30d508c1b3fcc906fc0 174 Gene3D G3DSA:2.60.120.10 64 151 1.0E-13 T 09-03-2017 IPR014710 RmlC-like jelly roll fold UA74_RS11600 2f59d42305530da200f398d279cd11df 298 Pfam PF01882 Protein of unknown function DUF58 37 121 4.0E-17 T 09-03-2017 IPR002881 Domain of unknown function DUF58 UA74_RS04900 ac2ac8504fdd803971789f57b7c210ed 438 Gene3D G3DSA:3.90.1200.10 84 107 3.1E-7 T 09-03-2017 UA74_RS04900 ac2ac8504fdd803971789f57b7c210ed 438 Gene3D G3DSA:3.90.1200.10 253 305 3.1E-7 T 09-03-2017 UA74_RS04900 ac2ac8504fdd803971789f57b7c210ed 438 Gene3D G3DSA:3.90.1200.10 193 216 3.1E-7 T 09-03-2017 UA74_RS04900 ac2ac8504fdd803971789f57b7c210ed 438 SUPERFAMILY SSF56112 190 307 1.14E-27 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS04900 ac2ac8504fdd803971789f57b7c210ed 438 SUPERFAMILY SSF56112 95 158 1.14E-27 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS04900 ac2ac8504fdd803971789f57b7c210ed 438 Pfam PF03109 ABC1 family 112 227 1.7E-31 T 09-03-2017 IPR004147 UbiB domain UA74_RS29090 0ef42225d69c0599bcb53d63d0a25b23 128 Gene3D G3DSA:3.10.180.10 15 123 8.7E-16 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS29090 0ef42225d69c0599bcb53d63d0a25b23 128 SUPERFAMILY SSF54593 15 121 1.93E-15 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS27370 5df395100fe4842f63c57d85a92182be 491 Pfam PF03703 Bacterial PH domain 64 144 4.1E-11 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS27370 5df395100fe4842f63c57d85a92182be 491 Pfam PF03703 Bacterial PH domain 409 478 1.2E-5 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS27370 5df395100fe4842f63c57d85a92182be 491 Pfam PF03703 Bacterial PH domain 241 302 2.7E-6 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS27370 5df395100fe4842f63c57d85a92182be 491 PIRSF PIRSF026631 1 479 1.2E-54 T 09-03-2017 IPR014529 Uncharacterised conserved protein UCP026631 UA74_RS22990 4bb2316f5b680dc9dc68ca580e432b02 322 SUPERFAMILY SSF100950 75 320 7.53E-57 T 09-03-2017 UA74_RS22990 4bb2316f5b680dc9dc68ca580e432b02 322 Gene3D G3DSA:3.40.50.1360 68 321 4.3E-68 T 09-03-2017 UA74_RS22990 4bb2316f5b680dc9dc68ca580e432b02 322 Pfam PF04198 Putative sugar-binding domain 74 321 5.6E-56 T 09-03-2017 IPR007324 Sugar-binding domain, putative GO:0030246 UA74_RS19945 7b1813aa1d4f21772a3ec641e069e728 404 Gene3D G3DSA:3.90.1200.10 110 245 3.9E-13 T 09-03-2017 UA74_RS19945 7b1813aa1d4f21772a3ec641e069e728 404 Pfam PF01636 Phosphotransferase enzyme family 29 256 1.1E-23 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS19945 7b1813aa1d4f21772a3ec641e069e728 404 SUPERFAMILY SSF56112 28 253 2.46E-29 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS26655 6f1c36924b734f78d935da4f732b9ae9 250 Gene3D G3DSA:3.90.1680.10 1 234 7.9E-68 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) UA74_RS26655 6f1c36924b734f78d935da4f732b9ae9 250 Pfam PF02586 SOS response associated peptidase (SRAP) 1 223 3.5E-63 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) UA74_RS26655 6f1c36924b734f78d935da4f732b9ae9 250 SUPERFAMILY SSF143081 2 235 2.75E-63 T 09-03-2017 IPR003738 SOS response associated peptidase (SRAP) UA74_RS28570 3ac63d149622236630ca05bebd8a600d 134 SUPERFAMILY SSF50331 10 127 4.13E-16 T 09-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal UA74_RS28570 3ac63d149622236630ca05bebd8a600d 134 Pfam PF03459 TOBE domain 66 125 2.1E-7 T 09-03-2017 IPR005116 Transport-associated OB, type 1 UA74_RS28570 3ac63d149622236630ca05bebd8a600d 134 Gene3D G3DSA:2.40.50.100 66 127 1.4E-18 T 09-03-2017 UA74_RS13335 b1eca4641f0f2ca079af52b700ea3ad3 337 Pfam PF01032 FecCD transport family 25 327 2.1E-79 T 09-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 UA74_RS13335 b1eca4641f0f2ca079af52b700ea3ad3 337 Gene3D G3DSA:1.10.3470.10 11 332 1.7E-87 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS13335 b1eca4641f0f2ca079af52b700ea3ad3 337 SUPERFAMILY SSF81345 10 327 8.63E-70 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS29585 ff95385e8eab64fc6215d6c7d833a7a1 58 Pfam PF04149 Domain of unknown function (DUF397) 6 56 3.4E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS13530 05018d119404b09180e447f7ebd08263 297 SMART SM00849 35 228 1.1E-14 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS13530 05018d119404b09180e447f7ebd08263 297 Gene3D G3DSA:3.60.15.10 13 250 1.1E-39 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS13530 05018d119404b09180e447f7ebd08263 297 Pfam PF00753 Metallo-beta-lactamase superfamily 34 228 6.5E-13 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS13530 05018d119404b09180e447f7ebd08263 297 SUPERFAMILY SSF56281 12 269 6.3E-43 T 09-03-2017 IPR001279 Metallo-beta-lactamase UA74_RS19525 337280d60a7b3c1db7a941f600e08797 287 Pfam PF13569 Domain of unknown function (DUF4132) 27 207 9.0E-31 T 09-03-2017 IPR025406 Domain of unknown function DUF4132 UA74_RS12490 64f2bb2a4ae42088d63edc09729060a2 406 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 2 304 1.4E-79 T 09-03-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA UA74_RS12490 64f2bb2a4ae42088d63edc09729060a2 406 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 297 8.1E-88 T 09-03-2017 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA UA74_RS18275 e588e2cadf055ae1fb184873c22c822b 398 SMART SM00530 11 66 9.8E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS18275 e588e2cadf055ae1fb184873c22c822b 398 SUPERFAMILY SSF47413 3 69 6.48E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS18275 e588e2cadf055ae1fb184873c22c822b 398 Gene3D G3DSA:1.10.260.40 5 72 6.5E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS21960 fb594e56f02ec218d42352d043bb642a 275 Gene3D G3DSA:3.40.50.720 3 210 4.7E-10 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21960 fb594e56f02ec218d42352d043bb642a 275 SUPERFAMILY SSF51735 52 243 4.35E-22 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS17635 3106ddbe5e14fa90ab0f84dc841e14cd 462 Pfam PF00668 Condensation domain 51 317 2.8E-40 T 09-03-2017 IPR001242 Condensation domain UA74_RS17635 3106ddbe5e14fa90ab0f84dc841e14cd 462 SUPERFAMILY SSF52777 22 199 6.23E-37 T 09-03-2017 UA74_RS17635 3106ddbe5e14fa90ab0f84dc841e14cd 462 SUPERFAMILY SSF52777 207 449 1.11E-28 T 09-03-2017 UA74_RS06565 c736a95ee3df86d375e20460095515d9 83 Gene3D G3DSA:1.10.1200.10 2 71 6.3E-8 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06565 c736a95ee3df86d375e20460095515d9 83 SUPERFAMILY SSF47336 3 71 9.21E-9 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS25610 82f23f51eef5a92b679bd788d7549cd8 167 Pfam PF11343 Protein of unknown function (DUF3145) 10 165 1.3E-69 T 09-03-2017 IPR021491 Protein of unknown function DUF3145 UA74_RS19120 434613aae812eb65812d5d438c06419a 409 Pfam PF13646 HEAT repeats 329 399 1.2E-8 T 09-03-2017 UA74_RS19120 434613aae812eb65812d5d438c06419a 409 Gene3D G3DSA:1.25.10.10 201 400 9.1E-15 T 09-03-2017 IPR011989 Armadillo-like helical UA74_RS19120 434613aae812eb65812d5d438c06419a 409 SMART SM00567 E-Z type HEAT repeats 365 394 550.0 T 09-03-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UA74_RS19120 434613aae812eb65812d5d438c06419a 409 SMART SM00567 E-Z type HEAT repeats 211 242 73.0 T 09-03-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UA74_RS19120 434613aae812eb65812d5d438c06419a 409 SMART SM00567 E-Z type HEAT repeats 335 363 16.0 T 09-03-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UA74_RS19120 434613aae812eb65812d5d438c06419a 409 SUPERFAMILY SSF160631 26 184 6.28E-11 T 09-03-2017 UA74_RS19120 434613aae812eb65812d5d438c06419a 409 SMART SM00860 37 184 1.3E-7 T 09-03-2017 IPR018958 SMI1/KNR4-like domain UA74_RS19120 434613aae812eb65812d5d438c06419a 409 SUPERFAMILY SSF48371 201 400 1.41E-16 T 09-03-2017 IPR016024 Armadillo-type fold GO:0005488 UA74_RS22050 27268c9cf54fdb8addb5ca8cad340ecf 307 Pfam PF10099 Anti-sigma-K factor rskA 65 303 1.2E-14 T 09-03-2017 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 UA74_RS05265 e40cda602db75ce495ee0d7541d86298 317 Pfam PF00487 Fatty acid desaturase 43 286 2.9E-27 T 09-03-2017 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_RS15775 153a878e323010d955987a7553e59517 346 Gene3D G3DSA:1.10.443.10 164 331 1.1E-20 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15775 153a878e323010d955987a7553e59517 346 Pfam PF00589 Phage integrase family 164 312 1.7E-11 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS15775 153a878e323010d955987a7553e59517 346 Gene3D G3DSA:1.10.150.130 47 148 8.1E-7 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS15775 153a878e323010d955987a7553e59517 346 SUPERFAMILY SSF56349 46 329 2.53E-33 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS00070 52d7145c0ff46f117a389d3f2be18ffd 385 Pfam PF04235 Protein of unknown function (DUF418) 225 379 7.3E-38 T 09-03-2017 IPR007349 Domain of unknown function DUF418 UA74_RS10395 8f4753d33e7000cb709a7ef65c58395b 219 Pfam PF01810 LysE type translocator 28 214 6.0E-24 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 UA74_RS19055 ca2055bef54a73595ebf4a5f43fff9d2 543 Pfam PF00561 alpha/beta hydrolase fold 88 484 3.0E-29 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS19055 ca2055bef54a73595ebf4a5f43fff9d2 543 Gene3D G3DSA:3.40.50.1820 378 499 3.4E-52 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19055 ca2055bef54a73595ebf4a5f43fff9d2 543 Gene3D G3DSA:3.40.50.1820 52 132 3.4E-52 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19055 ca2055bef54a73595ebf4a5f43fff9d2 543 Gene3D G3DSA:3.40.50.1820 176 310 3.4E-52 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19055 ca2055bef54a73595ebf4a5f43fff9d2 543 SUPERFAMILY SSF53474 86 133 4.77E-21 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19055 ca2055bef54a73595ebf4a5f43fff9d2 543 SUPERFAMILY SSF53474 354 484 4.77E-21 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS19055 ca2055bef54a73595ebf4a5f43fff9d2 543 SUPERFAMILY SSF53474 178 232 4.77E-21 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS11360 d8afdab05b2d656d8df96f936ad0992f 351 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 09-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_RS11360 d8afdab05b2d656d8df96f936ad0992f 351 Pfam PF00005 ABC transporter 43 184 7.1E-27 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS11360 d8afdab05b2d656d8df96f936ad0992f 351 Gene3D G3DSA:3.40.50.300 17 250 5.7E-56 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11360 d8afdab05b2d656d8df96f936ad0992f 351 SUPERFAMILY SSF52540 19 245 5.24E-52 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS11360 d8afdab05b2d656d8df96f936ad0992f 351 SMART SM00382 47 239 2.6E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS30115 4a288a6de6e481e9d731479bd7f7cc70 110 Pfam PF05139 Erythromycin esterase 1 70 4.6E-15 T 09-03-2017 IPR007815 Erythromycin esterase GO:0046677 UA74_RS30115 4a288a6de6e481e9d731479bd7f7cc70 110 SUPERFAMILY SSF159501 1 73 4.71E-16 T 09-03-2017 UA74_RS30115 4a288a6de6e481e9d731479bd7f7cc70 110 Gene3D G3DSA:3.40.1660.10 25 68 1.5E-4 T 09-03-2017 UA74_RS09185 247bfa70bc6708f09746515ef4a4bcfb 417 Pfam PF07730 Histidine kinase 212 277 4.9E-15 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS09185 247bfa70bc6708f09746515ef4a4bcfb 417 SUPERFAMILY SSF55874 293 409 1.14E-8 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS08730 ce1c7fd494a3377ef6cf8be3500603ad 348 SUPERFAMILY SSF101898 19 258 4.45E-8 T 09-03-2017 UA74_RS08730 ce1c7fd494a3377ef6cf8be3500603ad 348 Gene3D G3DSA:2.120.10.30 37 125 2.2E-5 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS08730 ce1c7fd494a3377ef6cf8be3500603ad 348 Gene3D G3DSA:2.120.10.30 240 258 2.2E-5 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS03315 6ea28050172182d4a03e478e3bc4cff0 224 Pfam PF01814 Hemerythrin HHE cation binding domain 13 144 1.4E-13 T 09-03-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 UA74_RS03315 6ea28050172182d4a03e478e3bc4cff0 224 Gene3D G3DSA:1.20.120.520 12 158 1.8E-24 T 09-03-2017 UA74_RS20640 1c6e26d9edfe8ec3ac675658cd74a9df 1297 SUPERFAMILY SSF52540 512 579 5.74E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20640 1c6e26d9edfe8ec3ac675658cd74a9df 1297 SUPERFAMILY SSF52540 1000 1116 5.74E-16 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20640 1c6e26d9edfe8ec3ac675658cd74a9df 1297 Gene3D G3DSA:3.40.50.300 1023 1097 4.3E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20640 1c6e26d9edfe8ec3ac675658cd74a9df 1297 Gene3D G3DSA:3.40.50.300 950 973 4.3E-15 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS20640 1c6e26d9edfe8ec3ac675658cd74a9df 1297 Pfam PF00271 Helicase conserved C-terminal domain 1020 1072 9.4E-6 T 09-03-2017 IPR001650 Helicase, C-terminal UA74_RS19700 d1df58ea487a3e00391292f507e71070 414 SUPERFAMILY SSF50969 61 204 4.32E-6 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_RS19700 d1df58ea487a3e00391292f507e71070 414 SUPERFAMILY SSF50969 292 351 4.32E-6 T 09-03-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_RS19700 d1df58ea487a3e00391292f507e71070 414 Gene3D G3DSA:2.140.10.10 287 368 2.0E-4 T 09-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain UA74_RS27390 d5ed37af862a95089b8b20367e933a2b 510 Pfam PF00361 Proton-conducting membrane transporter 131 418 1.9E-61 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS27390 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 1.7E-13 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS27390 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 1.7E-13 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS27390 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 1.7E-13 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS27390 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 1.7E-13 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS27390 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.7E-13 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS29840 7a4a5c8c27c28e0dbdebff1b87190c25 229 Gene3D G3DSA:3.40.1280.10 60 222 5.1E-41 T 09-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_RS29840 7a4a5c8c27c28e0dbdebff1b87190c25 229 Pfam PF00588 SpoU rRNA Methylase family 80 216 3.3E-24 T 09-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_RS29840 7a4a5c8c27c28e0dbdebff1b87190c25 229 SUPERFAMILY SSF75217 63 222 7.85E-38 T 09-03-2017 IPR029028 Alpha/beta knot methyltransferases UA74_RS09275 fedd25e55c1d508a0edb9005a57eeb4a 312 SUPERFAMILY SSF56112 36 259 1.34E-20 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS09275 fedd25e55c1d508a0edb9005a57eeb4a 312 Gene3D G3DSA:3.90.1200.10 143 281 6.9E-8 T 09-03-2017 UA74_RS03150 290b62a8827c5266f43d3532133c9802 327 Pfam PF00487 Fatty acid desaturase 68 286 9.5E-19 T 09-03-2017 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_RS03150 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 68 90 3.5E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS03150 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 91 111 3.5E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS03150 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 271 285 3.5E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS03150 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 228 249 3.5E-19 T 09-03-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_RS11765 a0e6a27651f5471b5bd8840daf2ebe4e 209 Gene3D G3DSA:3.40.50.300 13 194 1.5E-9 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS03705 27f23c3406b6df5d6b54ae3f0b157f5a 585 SUPERFAMILY SSF143975 20 383 8.5E-112 T 09-03-2017 UA74_RS03705 27f23c3406b6df5d6b54ae3f0b157f5a 585 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 131 141 - T 09-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS03705 27f23c3406b6df5d6b54ae3f0b157f5a 585 Pfam PF00920 Dehydratase family 49 567 3.2E-167 T 09-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_RS03705 27f23c3406b6df5d6b54ae3f0b157f5a 585 SUPERFAMILY SSF52016 385 573 2.12E-53 T 09-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel UA74_RS24345 6e71b268c377a0e019e71298f7e1e696 180 SUPERFAMILY SSF46785 3 173 1.24E-27 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS24345 6e71b268c377a0e019e71298f7e1e696 180 Pfam PF03551 Transcriptional regulator PadR-like family 6 77 4.9E-10 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS24345 6e71b268c377a0e019e71298f7e1e696 180 Gene3D G3DSA:1.10.10.10 2 82 8.5E-19 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS20160 c70b4b21f59cc68e23666900b52ef130 126 SUPERFAMILY SSF82607 26 116 6.28E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS20160 c70b4b21f59cc68e23666900b52ef130 126 Pfam PF02575 YbaB/EbfC DNA-binding family 41 117 4.3E-9 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS20160 c70b4b21f59cc68e23666900b52ef130 126 Gene3D G3DSA:3.30.1310.10 24 119 6.0E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS15070 b59fa720c26fd07dbc9c890e2881d814 205 Pfam PF04961 Formiminotransferase-cyclodeaminase 5 183 1.1E-48 T 09-03-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 UA74_RS15070 b59fa720c26fd07dbc9c890e2881d814 205 SUPERFAMILY SSF101262 3 202 2.22E-40 T 09-03-2017 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 UA74_RS06560 7ee36d806a7b15c469629a8e04080a05 87 Gene3D G3DSA:1.10.1200.10 3 76 1.3E-11 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06560 7ee36d806a7b15c469629a8e04080a05 87 SUPERFAMILY SSF47336 3 80 9.95E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS06560 7ee36d806a7b15c469629a8e04080a05 87 Pfam PF00550 Phosphopantetheine attachment site 8 73 3.2E-6 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS00910 28dd14b066f10fce4dff8359783a2abd 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 288 5.3E-35 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00910 28dd14b066f10fce4dff8359783a2abd 295 Gene3D G3DSA:1.10.3720.10 74 280 5.0E-13 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS00910 28dd14b066f10fce4dff8359783a2abd 295 SUPERFAMILY SSF161098 75 276 7.52E-14 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS01730 675a2cfb8d4b6acea90f8b0884d0be54 272 Pfam PF00950 ABC 3 transport family 7 258 3.5E-43 T 09-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_RS01730 675a2cfb8d4b6acea90f8b0884d0be54 272 Gene3D G3DSA:1.10.3470.10 12 239 9.5E-5 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS01730 675a2cfb8d4b6acea90f8b0884d0be54 272 SUPERFAMILY SSF81345 3 257 9.02E-31 T 09-03-2017 IPR029022 ABC transporter, BtuC-like UA74_RS18850 8213dd5ad96c8be4549f1ef17dc75deb 247 Pfam PF07398 MDMPI C-terminal domain 144 238 1.9E-13 T 09-03-2017 IPR010872 MDMPI C-terminal UA74_RS18850 8213dd5ad96c8be4549f1ef17dc75deb 247 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 223 7.0E-26 T 09-03-2017 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_RS18850 8213dd5ad96c8be4549f1ef17dc75deb 247 SUPERFAMILY SSF109854 2 136 9.77E-10 T 09-03-2017 UA74_RS18850 8213dd5ad96c8be4549f1ef17dc75deb 247 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 129 3.0E-20 T 09-03-2017 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_RS30205 8acb1d1f89161ccbbab9b635a13ede56 276 PIRSF PIRSF006648 1 275 8.9E-75 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS30205 8acb1d1f89161ccbbab9b635a13ede56 276 Pfam PF01061 ABC-2 type transporter 26 239 3.8E-25 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS09435 0bee78598f51f15844fd4d408b2d66d9 158 SUPERFAMILY SSF47413 21 59 3.26E-7 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09435 0bee78598f51f15844fd4d408b2d66d9 158 Gene3D G3DSA:1.10.260.40 22 71 1.0E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS28285 de48f5863877e40ab4df1b4fb3993f52 226 Pfam PF07884 Vitamin K epoxide reductase family 45 176 1.4E-30 T 09-03-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 UA74_RS28285 de48f5863877e40ab4df1b4fb3993f52 226 SMART SM00756 39 180 5.4E-51 T 09-03-2017 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 UA74_RS09125 504d48192128d7cd74f9db81408427c6 121 Pfam PF11255 Protein of unknown function (DUF3054) 12 112 3.4E-25 T 09-03-2017 IPR021414 Protein of unknown function DUF3054 UA74_RS00285 e8ce3f77a86efdbae2a595ea2a8cafe1 180 Pfam PF03413 Peptidase propeptide and YPEB domain 88 146 1.2E-14 T 09-03-2017 IPR025711 PepSY domain UA74_RS05590 29b46185bc35dd55d09e70d05a03a5e4 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 5.2E-16 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS05590 29b46185bc35dd55d09e70d05a03a5e4 314 Gene3D G3DSA:1.10.10.10 5 87 8.4E-20 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05590 29b46185bc35dd55d09e70d05a03a5e4 314 SUPERFAMILY SSF46785 6 87 8.52E-17 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05590 29b46185bc35dd55d09e70d05a03a5e4 314 Pfam PF03466 LysR substrate binding domain 96 296 2.3E-14 T 09-03-2017 IPR005119 LysR, substrate-binding UA74_RS05590 29b46185bc35dd55d09e70d05a03a5e4 314 Gene3D G3DSA:3.40.190.10 180 265 1.5E-6 T 09-03-2017 UA74_RS05590 29b46185bc35dd55d09e70d05a03a5e4 314 Gene3D G3DSA:3.40.190.10 96 179 8.7E-8 T 09-03-2017 UA74_RS05590 29b46185bc35dd55d09e70d05a03a5e4 314 SUPERFAMILY SSF53850 97 297 4.78E-17 T 09-03-2017 UA74_RS25010 2187bda8e3e40e741c28f9c0bc7e3c58 483 Gene3D G3DSA:3.30.2010.10 294 333 1.1E-4 T 09-03-2017 UA74_RS11535 c8feceb1977add77d9c60f5739481b65 212 Pfam PF07510 Protein of unknown function (DUF1524) 107 205 2.3E-8 T 09-03-2017 IPR011089 Domain of unknown function DUF1524 UA74_RS10690 455311c4a5bdd3f7be3da3a073d8ef05 285 SMART SM00382 56 256 1.9E-7 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS10690 455311c4a5bdd3f7be3da3a073d8ef05 285 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 257 278 7.8E-11 T 09-03-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal UA74_RS10690 455311c4a5bdd3f7be3da3a073d8ef05 285 Pfam PF00005 ABC transporter 47 207 1.6E-32 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS10690 455311c4a5bdd3f7be3da3a073d8ef05 285 SUPERFAMILY SSF52540 30 278 2.62E-65 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS10690 455311c4a5bdd3f7be3da3a073d8ef05 285 Gene3D G3DSA:3.40.50.300 29 276 6.3E-70 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS02255 7c6db44532cf296c36858fa426e77f9f 350 SUPERFAMILY SSF51735 1 316 2.55E-41 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS02255 7c6db44532cf296c36858fa426e77f9f 350 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 187 1.0E-21 T 09-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 UA74_RS02255 7c6db44532cf296c36858fa426e77f9f 350 Gene3D G3DSA:3.40.50.720 5 316 3.2E-32 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS20585 7abbf66e69647fc67e05229c2c2a9104 273 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 46 170 2.0E-25 T 09-03-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component UA74_RS16155 9d085d01192964866d0a707b4e4faf4b 118 Pfam PF01381 Helix-turn-helix 24 77 4.1E-5 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS16155 9d085d01192964866d0a707b4e4faf4b 118 SUPERFAMILY SSF47413 26 78 4.57E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS16155 9d085d01192964866d0a707b4e4faf4b 118 Gene3D G3DSA:1.10.260.40 9 77 2.9E-6 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS09270 6f7a8521aa4105dcde6f83f3f0d1a369 254 Pfam PF03883 Protein of unknown function (DUF328) 2 212 9.8E-33 T 09-03-2017 IPR005583 Peroxide stress protein YaaA UA74_RS04335 7a7ceb04aec19794e82790ff9069416d 97 SUPERFAMILY SSF53756 1 82 1.84E-15 T 09-03-2017 UA74_RS04335 7a7ceb04aec19794e82790ff9069416d 97 Gene3D G3DSA:3.40.50.2000 2 65 9.7E-10 T 09-03-2017 UA74_RS04335 7a7ceb04aec19794e82790ff9069416d 97 Pfam PF00534 Glycosyl transferases group 1 1 66 4.1E-8 T 09-03-2017 IPR001296 Glycosyl transferase, family 1 UA74_RS02415 db454c4d2f15b27e91b16544d8dcb004 110 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 96 5.0E-5 T 09-03-2017 IPR022536 ESX-1 secretion-associated protein EspC UA74_RS25925 9bc3687f271725d6dd6b5475a1274259 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 104 3.3E-5 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS25925 9bc3687f271725d6dd6b5475a1274259 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 2.1E-6 T 09-03-2017 IPR001451 Hexapeptide repeat UA74_RS25925 9bc3687f271725d6dd6b5475a1274259 174 SUPERFAMILY SSF51161 2 152 2.5E-41 T 09-03-2017 IPR011004 Trimeric LpxA-like UA74_RS25925 9bc3687f271725d6dd6b5475a1274259 174 Gene3D G3DSA:2.160.10.10 8 158 1.2E-39 T 09-03-2017 UA74_RS08290 182334e83ae9962d5584fe989caed1b7 442 Gene3D G3DSA:3.40.190.10 51 163 4.9E-7 T 09-03-2017 UA74_RS08290 182334e83ae9962d5584fe989caed1b7 442 Pfam PF13416 Bacterial extracellular solute-binding protein 66 362 4.2E-12 T 09-03-2017 UA74_RS08290 182334e83ae9962d5584fe989caed1b7 442 SUPERFAMILY SSF53850 43 406 2.57E-36 T 09-03-2017 UA74_RS08290 182334e83ae9962d5584fe989caed1b7 442 Gene3D G3DSA:3.40.190.10 164 363 1.2E-19 T 09-03-2017 UA74_RS06615 a2384c6a240cd99493c8035c7ff64126 318 PIRSF PIRSF000707 1 318 1.1E-91 T 09-03-2017 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UA74_RS06615 a2384c6a240cd99493c8035c7ff64126 318 Pfam PF01636 Phosphotransferase enzyme family 54 268 7.3E-23 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS06615 a2384c6a240cd99493c8035c7ff64126 318 SUPERFAMILY SSF56112 54 285 3.95E-25 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS06615 a2384c6a240cd99493c8035c7ff64126 318 Gene3D G3DSA:3.90.1200.10 117 294 9.9E-16 T 09-03-2017 UA74_RS02600 4a4540857af4095636f24b9052585c04 543 Pfam PF00361 Proton-conducting membrane transporter 129 424 1.2E-62 T 09-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02600 4a4540857af4095636f24b9052585c04 543 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 5 514 2.4E-170 T 09-03-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02600 4a4540857af4095636f24b9052585c04 543 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 165 189 6.7E-36 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02600 4a4540857af4095636f24b9052585c04 543 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 382 408 6.7E-36 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02600 4a4540857af4095636f24b9052585c04 543 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 330 349 6.7E-36 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02600 4a4540857af4095636f24b9052585c04 543 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 135 154 6.7E-36 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS02600 4a4540857af4095636f24b9052585c04 543 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 242 266 6.7E-36 T 09-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_RS06045 6639ee64f7f504715cd22f72a71ac355 300 Gene3D G3DSA:3.90.1200.10 107 259 1.1E-13 T 09-03-2017 UA74_RS06045 6639ee64f7f504715cd22f72a71ac355 300 SUPERFAMILY SSF56112 43 278 7.39E-23 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS06045 6639ee64f7f504715cd22f72a71ac355 300 Pfam PF01636 Phosphotransferase enzyme family 54 257 7.8E-18 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS26410 2f4257fe0a3c2078471b41fda6bbd92c 365 Pfam PF07690 Major Facilitator Superfamily 3 328 9.2E-31 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS26410 2f4257fe0a3c2078471b41fda6bbd92c 365 Gene3D G3DSA:1.20.1250.20 199 355 1.2E-12 T 09-03-2017 UA74_RS26410 2f4257fe0a3c2078471b41fda6bbd92c 365 Gene3D G3DSA:1.20.1250.20 4 173 7.9E-22 T 09-03-2017 UA74_RS26410 2f4257fe0a3c2078471b41fda6bbd92c 365 SUPERFAMILY SSF103473 2 355 2.75E-41 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS00090 40eb8383057eb7dce1b7d2a7c1627c44 311 SUPERFAMILY SSF144091 80 264 3.27E-42 T 09-03-2017 UA74_RS00090 40eb8383057eb7dce1b7d2a7c1627c44 311 Gene3D G3DSA:1.20.1540.10 80 254 3.0E-40 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UA74_RS00090 40eb8383057eb7dce1b7d2a7c1627c44 311 Pfam PF01694 Rhomboid family 125 255 2.8E-28 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UA74_RS28115 494210571bbf7217682bb0c1ef133caf 175 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 46 142 2.0E-30 T 09-03-2017 IPR032093 Phospholipase D, N-terminal UA74_RS26620 d09a616194a1218cc50d27cfa6c9242f 307 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 117 3.3E-26 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_RS26620 d09a616194a1218cc50d27cfa6c9242f 307 SUPERFAMILY SSF111331 2 306 1.44E-57 T 09-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain UA74_RS26620 d09a616194a1218cc50d27cfa6c9242f 307 SMART SM00046 2 131 1.8E-14 T 09-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_RS26620 d09a616194a1218cc50d27cfa6c9242f 307 Gene3D G3DSA:3.40.50.10330 20 88 4.3E-5 T 09-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 UA74_RS17810 52f9a287c013973c2600c518f1b2c118 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 4.1E-16 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS02460 0ba1a3c73adefdb772fe7a2cd7173abd 290 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 285 5.2E-85 T 09-03-2017 UA74_RS02460 0ba1a3c73adefdb772fe7a2cd7173abd 290 PIRSF PIRSF005355 1 290 9.9E-82 T 09-03-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 UA74_RS02460 0ba1a3c73adefdb772fe7a2cd7173abd 290 Pfam PF01040 UbiA prenyltransferase family 20 250 1.8E-33 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 UA74_RS02460 0ba1a3c73adefdb772fe7a2cd7173abd 290 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 287 20.667 T 09-03-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UA74_RS24135 800fb3d36a9b5c42e564165054030179 195 Pfam PF12079 Protein of unknown function (DUF3558) 6 190 1.9E-23 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS30030 dd1076a1573031e4f693c63e0209f1ad 305 Pfam PF13845 Septum formation 77 283 1.4E-37 T 09-03-2017 IPR026004 Septum formation-related domain UA74_RS19085 9b7232daa209700ab5520da7a7acef29 264 Gene3D G3DSA:3.40.50.300 4 227 1.4E-60 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19085 9b7232daa209700ab5520da7a7acef29 264 SMART SM00382 27 211 8.9E-18 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS19085 9b7232daa209700ab5520da7a7acef29 264 Pfam PF00005 ABC transporter 20 167 7.5E-31 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS19085 9b7232daa209700ab5520da7a7acef29 264 SUPERFAMILY SSF52540 3 224 2.24E-58 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 SUPERFAMILY SSF143034 2 63 7.72E-21 T 09-03-2017 UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 09-03-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.2E-14 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.2E-14 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.2E-14 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 1.7E-22 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 Pfam PF01632 Ribosomal protein L35 2 62 5.0E-24 T 09-03-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS21755 42cb9d0e4d5b9457e418b5cc56de87fb 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.821 T 09-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_RS01110 095789d7ae2e50852ec0f12afe40424b 396 Gene3D G3DSA:3.20.20.80 131 369 1.6E-12 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS01110 095789d7ae2e50852ec0f12afe40424b 396 SUPERFAMILY SSF51055 38 90 2.49E-15 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS01110 095789d7ae2e50852ec0f12afe40424b 396 SUPERFAMILY SSF51445 115 369 4.33E-20 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS01110 095789d7ae2e50852ec0f12afe40424b 396 Gene3D G3DSA:2.10.10.20 39 87 1.1E-19 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS01110 095789d7ae2e50852ec0f12afe40424b 396 Pfam PF02839 Carbohydrate binding domain 42 84 2.4E-13 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS01110 095789d7ae2e50852ec0f12afe40424b 396 SMART SM00495 42 87 5.7E-16 T 09-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_RS08445 c09e62831dd7c873c3ed84cc53f8c088 141 Gene3D G3DSA:3.50.80.10 2 140 1.5E-47 T 09-03-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain UA74_RS08445 c09e62831dd7c873c3ed84cc53f8c088 141 SUPERFAMILY SSF69500 1 140 1.96E-40 T 09-03-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain UA74_RS08445 c09e62831dd7c873c3ed84cc53f8c088 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 3.2E-45 T 09-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 UA74_RS08445 c09e62831dd7c873c3ed84cc53f8c088 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 27.837 T 09-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 UA74_RS08445 c09e62831dd7c873c3ed84cc53f8c088 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 140 5.7E-33 T 09-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 UA74_RS23545 2e420ae612d5c7438f6f4782f31fa1f8 136 SUPERFAMILY SSF55874 40 123 1.6E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS23545 2e420ae612d5c7438f6f4782f31fa1f8 136 Pfam PF13581 Histidine kinase-like ATPase domain 18 122 2.2E-12 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS29375 d3063738a179544ccf0fb01e922eec1e 207 Pfam PF12079 Protein of unknown function (DUF3558) 25 185 3.4E-14 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS19610 203bbdbe0ea5f49c1f5fa3489d9d8887 138 SUPERFAMILY SSF46955 1 112 8.06E-26 T 09-03-2017 IPR009061 Putative DNA-binding domain UA74_RS19610 203bbdbe0ea5f49c1f5fa3489d9d8887 138 Gene3D G3DSA:1.10.1660.10 1 125 2.2E-32 T 09-03-2017 UA74_RS19610 203bbdbe0ea5f49c1f5fa3489d9d8887 138 Pfam PF13411 MerR HTH family regulatory protein 1 61 6.5E-18 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19610 203bbdbe0ea5f49c1f5fa3489d9d8887 138 SMART SM00422 1 69 1.0E-21 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19610 203bbdbe0ea5f49c1f5fa3489d9d8887 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.8E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19610 203bbdbe0ea5f49c1f5fa3489d9d8887 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.8E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS19610 203bbdbe0ea5f49c1f5fa3489d9d8887 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.8E-10 T 09-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_RS02125 ee98cd54cb9e85b7b987189b9f1cf561 186 SUPERFAMILY SSF55826 41 178 3.92E-20 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS02125 ee98cd54cb9e85b7b987189b9f1cf561 186 Gene3D G3DSA:3.90.960.10 41 178 2.2E-21 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS02125 ee98cd54cb9e85b7b987189b9f1cf561 186 Pfam PF04073 Aminoacyl-tRNA editing domain 48 167 8.3E-15 T 09-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_RS18855 4c2ed4c103540b1467146237add15eaa 251 Gene3D G3DSA:3.30.450.40 87 250 1.7E-45 T 09-03-2017 IPR029016 GAF domain-like UA74_RS18855 4c2ed4c103540b1467146237add15eaa 251 Pfam PF01614 Bacterial transcriptional regulator 130 248 2.3E-25 T 09-03-2017 IPR014757 Transcription regulator IclR, C-terminal UA74_RS18855 4c2ed4c103540b1467146237add15eaa 251 SUPERFAMILY SSF55781 87 250 1.77E-39 T 09-03-2017 IPR029016 GAF domain-like UA74_RS09585 7f554af6e5256cbf459ae8a2738a7bb5 165 Gene3D G3DSA:1.20.90.10 32 143 1.2E-40 T 09-03-2017 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 UA74_RS09585 7f554af6e5256cbf459ae8a2738a7bb5 165 Pfam PF09056 Prokaryotic phospholipase A2 38 143 1.6E-40 T 09-03-2017 IPR015141 Phospholipase A2, prokaryotic/fungal UA74_RS09585 7f554af6e5256cbf459ae8a2738a7bb5 165 SUPERFAMILY SSF48619 34 143 3.79E-35 T 09-03-2017 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 UA74_RS05760 936bda615867f61368359e827669c4c8 500 Pfam PF03559 NDP-hexose 2,3-dehydratase 29 236 1.1E-80 T 09-03-2017 IPR005212 NDP-hexose 2,3-dehydratase UA74_RS05760 936bda615867f61368359e827669c4c8 500 Pfam PF03559 NDP-hexose 2,3-dehydratase 285 486 3.6E-75 T 09-03-2017 IPR005212 NDP-hexose 2,3-dehydratase UA74_RS20045 9c8cee1907af364e405e0111fb842e31 697 Pfam PF01757 Acyltransferase family 349 672 1.5E-27 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS07950 193c13a82553b90558deb19f1e99761b 678 Pfam PF05425 Copper resistance protein D 250 346 5.0E-17 T 09-03-2017 IPR008457 Copper resistance protein D GO:0016021 UA74_RS07950 193c13a82553b90558deb19f1e99761b 678 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 400 643 3.8E-85 T 09-03-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related UA74_RS11855 1bbbd511308f9fe33b8f72d26a855db7 143 Pfam PF14325 Domain of unknown function (DUF4383) 20 143 2.0E-42 T 09-03-2017 IPR025492 Protein of unknown function DUF4383 UA74_RS23350 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 70 83 2.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23350 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 7 25 2.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23350 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 27 42 2.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23350 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 231 253 2.1E-7 T 09-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_RS23350 dbde98409c19ae8bafb95d0dcdf36f6b 258 Pfam PF12697 Alpha/beta hydrolase family 4 247 8.7E-16 T 09-03-2017 IPR000073 Alpha/beta hydrolase fold-1 UA74_RS23350 dbde98409c19ae8bafb95d0dcdf36f6b 258 SUPERFAMILY SSF53474 3 256 2.13E-28 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS23350 dbde98409c19ae8bafb95d0dcdf36f6b 258 Gene3D G3DSA:3.40.50.1820 3 255 2.1E-27 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17750 1c61d2911bf1acc6bfc3d807d0f4624e 249 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 45 1.7E-12 T 09-03-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_RS17750 1c61d2911bf1acc6bfc3d807d0f4624e 249 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 218 1.2E-57 T 09-03-2017 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 UA74_RS17750 1c61d2911bf1acc6bfc3d807d0f4624e 249 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 182 3.8E-45 T 09-03-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_RS29350 b54055343639e4b444efa3f71ed37356 323 Pfam PF06089 L-asparaginase II 6 310 9.0E-111 T 09-03-2017 IPR010349 L-asparaginase II UA74_RS01120 5466728265d83aeeb7548a6730096cc2 146 Gene3D G3DSA:2.60.40.1120 54 118 5.9E-4 T 09-03-2017 IPR014766 Carboxypeptidase, regulatory domain UA74_RS01120 5466728265d83aeeb7548a6730096cc2 146 SUPERFAMILY SSF49464 54 109 1.77E-5 T 09-03-2017 IPR008969 Carboxypeptidase-like, regulatory domain UA74_RS07805 c54c63e0a08fa67eaf618668d1bd03b7 137 Pfam PF13471 Transglutaminase-like superfamily 23 132 4.1E-26 T 09-03-2017 IPR032708 Microcin J25-processing protein McjB, C-terminal UA74_RS21325 7bfbaa3e911cf7f2de86ef4e1c306757 352 SMART SM01329 4 346 9.8E-158 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS21325 7bfbaa3e911cf7f2de86ef4e1c306757 352 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 09-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UA74_RS21325 7bfbaa3e911cf7f2de86ef4e1c306757 352 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 344 2.1E-85 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS21325 7bfbaa3e911cf7f2de86ef4e1c306757 352 SUPERFAMILY SSF53659 1 349 9.54E-109 T 09-03-2017 UA74_RS21325 7bfbaa3e911cf7f2de86ef4e1c306757 352 Gene3D G3DSA:3.40.718.10 1 349 3.5E-109 T 09-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_RS21325 7bfbaa3e911cf7f2de86ef4e1c306757 352 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 349 7.5E-153 T 09-03-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 UA74_RS12585 d4a2f72394513954556e9abf4cd89494 312 Pfam PF02628 Cytochrome oxidase assembly protein 4 179 8.1E-14 T 09-03-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 UA74_RS24010 386a31148d4bee6d972814682122e860 222 SUPERFAMILY SSF140453 57 122 1.96E-6 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS10475 a5a81ca153ce07ad7dab66021a072c8f 325 Gene3D G3DSA:3.90.25.10 176 315 2.6E-46 T 09-03-2017 UA74_RS10475 a5a81ca153ce07ad7dab66021a072c8f 325 Gene3D G3DSA:3.40.50.720 6 175 2.2E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10475 a5a81ca153ce07ad7dab66021a072c8f 325 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 305 5.5E-51 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10475 a5a81ca153ce07ad7dab66021a072c8f 325 SUPERFAMILY SSF51735 7 313 4.34E-87 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS11390 6eb7d421fe59d80b4aae5a1786bda6bc 264 Pfam PF01061 ABC-2 type transporter 20 227 3.3E-29 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS11390 6eb7d421fe59d80b4aae5a1786bda6bc 264 PIRSF PIRSF006648 1 263 3.6E-65 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS17760 b08d299695c5ec7936d44f3b6839cff8 214 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 20 194 2.3E-16 T 09-03-2017 IPR013382 CRISPR-associated protein Cse2 UA74_RS17760 b08d299695c5ec7936d44f3b6839cff8 214 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 23 193 4.2E-25 T 09-03-2017 IPR013382 CRISPR-associated protein Cse2 UA74_RS02380 cc28f037277ed73d1742b6d57a06840f 612 Pfam PF05140 ResB-like family 26 513 4.7E-126 T 09-03-2017 IPR007816 ResB-like domain UA74_RS20735 fe55abc0744e0f3fb0a8278d69f33217 279 SUPERFAMILY SSF52266 70 255 3.83E-14 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS20735 fe55abc0744e0f3fb0a8278d69f33217 279 Gene3D G3DSA:3.40.50.1110 70 258 2.1E-12 T 09-03-2017 IPR013830 SGNH hydrolase-type esterase domain UA74_RS04965 3a1c4cc10efa9a19a3a9fee4c50a633c 300 PIRSF PIRSF003097 1 300 1.4E-69 T 09-03-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 UA74_RS04965 3a1c4cc10efa9a19a3a9fee4c50a633c 300 Pfam PF02687 FtsX-like permease family 179 291 2.0E-10 T 09-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_RS16400 8ea56bad215ef1211fca29d9fffd0b09 379 SUPERFAMILY SSF56726 188 292 3.4E-5 T 09-03-2017 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 UA74_RS16400 8ea56bad215ef1211fca29d9fffd0b09 379 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 225 333 5.2E-10 T 09-03-2017 IPR024534 Domain of unknown function DUF2220 UA74_RS16400 8ea56bad215ef1211fca29d9fffd0b09 379 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 1 68 1.3E-5 T 09-03-2017 IPR024466 Conserved hypothetical protein CHP02679, N terminus UA74_RS17610 02f1fec1c527168ed804afabfef63149 228 Gene3D G3DSA:3.40.50.150 22 228 2.2E-64 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS17610 02f1fec1c527168ed804afabfef63149 228 Pfam PF01596 O-methyltransferase 26 227 3.3E-50 T 09-03-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 UA74_RS17610 02f1fec1c527168ed804afabfef63149 228 SUPERFAMILY SSF53335 14 228 4.56E-43 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15190 12ecdc788b058b0f98732007841d078c 31 Gene3D G3DSA:1.10.3300.10 2 30 3.4E-11 T 09-03-2017 IPR023286 ABATE domain UA74_RS15190 12ecdc788b058b0f98732007841d078c 31 Pfam PF11706 CGNR zinc finger 2 30 6.1E-12 T 09-03-2017 IPR021005 Zinc finger, CGNR UA74_RS15190 12ecdc788b058b0f98732007841d078c 31 SUPERFAMILY SSF160904 2 29 3.53E-12 T 09-03-2017 UA74_RS13040 e235196239b438c00eb1ee647c81cc52 212 Pfam PF14230 Domain of unknown function (DUF4333) 127 204 1.2E-24 T 09-03-2017 IPR025637 Domain of unknown function DUF4333 UA74_RS14450 305b9642882aae405dac054950a21f8b 111 Gene3D G3DSA:3.10.450.50 14 110 5.7E-5 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS14450 305b9642882aae405dac054950a21f8b 111 SUPERFAMILY SSF54427 4 110 3.29E-9 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS14450 305b9642882aae405dac054950a21f8b 111 Pfam PF14534 Domain of unknown function (DUF4440) 9 97 6.6E-8 T 09-03-2017 IPR027843 Domain of unknown function DUF4440 UA74_RS21820 64cbb3919883be15c2f0c272810b321e 393 SUPERFAMILY SSF54060 175 386 3.88E-55 T 09-03-2017 UA74_RS21820 64cbb3919883be15c2f0c272810b321e 393 Pfam PF04231 Endonuclease I 178 386 2.2E-40 T 09-03-2017 IPR007346 Endonuclease I GO:0004518 UA74_RS07365 641f34bcdb26622d0f2c358195294645 492 Pfam PF04228 Putative neutral zinc metallopeptidase 136 271 2.6E-6 T 09-03-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative UA74_RS18830 a6eae5c873180819c2f6e5b1069c5990 267 SUPERFAMILY SSF161098 3 267 6.8E-70 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18830 a6eae5c873180819c2f6e5b1069c5990 267 Gene3D G3DSA:1.10.3720.10 2 254 9.6E-66 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18830 a6eae5c873180819c2f6e5b1069c5990 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 256 6.7E-21 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS27940 328e899e074e9dc2a1109cb6a604c9d9 215 Pfam PF09335 SNARE associated Golgi protein 40 162 8.7E-16 T 09-03-2017 IPR032816 SNARE associated Golgi protein UA74_RS08800 dca849d86073f8457c0c974f5b50573b 332 Pfam PF03812 2-keto-3-deoxygluconate permease 14 316 6.6E-109 T 09-03-2017 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 UA74_RS08800 dca849d86073f8457c0c974f5b50573b 332 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 35 317 8.0E-74 T 09-03-2017 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 UA74_RS10625 ee39dad7054b63050fe2f088cf53c59c 600 Pfam PF02554 Carbon starvation protein CstA 1 348 7.1E-112 T 09-03-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 UA74_RS10625 ee39dad7054b63050fe2f088cf53c59c 600 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 392 510 4.7E-30 T 09-03-2017 IPR025299 CstA, C-terminal domain UA74_RS23290 8706043ecd017e92229a4899b6dc8087 245 SUPERFAMILY SSF55486 32 237 1.09E-8 T 09-03-2017 UA74_RS23290 8706043ecd017e92229a4899b6dc8087 245 Gene3D G3DSA:3.40.390.10 109 243 1.4E-9 T 09-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 UA74_RS05325 f75def23ee23604dbca98f7c8f6f8fbd 88 Gene3D G3DSA:1.10.10.10 21 63 7.8E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05325 f75def23ee23604dbca98f7c8f6f8fbd 88 SUPERFAMILY SSF46785 20 63 1.36E-8 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS05325 f75def23ee23604dbca98f7c8f6f8fbd 88 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 64 2.0E-10 T 09-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_RS12825 c66ff7b75d66886bae86813b8cde726e 301 PIRSF PIRSF005355 8 301 3.4E-36 T 09-03-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 UA74_RS12825 c66ff7b75d66886bae86813b8cde726e 301 Pfam PF01040 UbiA prenyltransferase family 40 270 1.1E-16 T 09-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 UA74_RS16295 70094c4051c109e0f8d8c9a63a67aec2 349 Pfam PF13814 Replication-relaxation 44 227 4.2E-50 T 09-03-2017 IPR025855 Plasmid replication-relaxation UA74_RS12095 f8a54ead79d237a099e6dd63168bc795 259 Pfam PF05988 Bacterial protein of unknown function (DUF899) 13 197 2.1E-19 T 09-03-2017 IPR010296 Protein of unknown function DUF899, thioredoxin-like UA74_RS12095 f8a54ead79d237a099e6dd63168bc795 259 Gene3D G3DSA:3.40.30.10 52 182 9.8E-5 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS22125 247380fc146bcd7a5a8767853217cdda 116 SUPERFAMILY SSF51197 14 116 2.79E-10 T 09-03-2017 UA74_RS22125 247380fc146bcd7a5a8767853217cdda 116 Gene3D G3DSA:3.60.130.10 11 116 9.2E-7 T 09-03-2017 UA74_RS22125 247380fc146bcd7a5a8767853217cdda 116 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 7 116 1.0E-8 T 09-03-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 UA74_RS15930 0dd300ac620b62ad77343affdab1dca2 165 Pfam PF01930 Domain of unknown function DUF83 9 164 4.7E-35 T 09-03-2017 IPR022765 Dna2/Cas4, domain of unknown function DUF83 UA74_RS01675 68230c789e450ccde3ead582a142bddc 419 Gene3D G3DSA:1.10.150.130 74 171 1.3E-12 T 09-03-2017 IPR023109 Integrase/recombinase, N-terminal UA74_RS01675 68230c789e450ccde3ead582a142bddc 419 Pfam PF00589 Phage integrase family 195 371 3.6E-15 T 09-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS01675 68230c789e450ccde3ead582a142bddc 419 SUPERFAMILY SSF56349 73 377 1.91E-51 T 09-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_RS01675 68230c789e450ccde3ead582a142bddc 419 Gene3D G3DSA:1.10.443.10 178 385 4.9E-32 T 09-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_RS01675 68230c789e450ccde3ead582a142bddc 419 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 73 124 1.2E-6 T 09-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_RS05075 ab88792843963975e7a3227768867f2f 818 Gene3D G3DSA:3.40.50.300 276 375 5.3E-5 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05075 ab88792843963975e7a3227768867f2f 818 SUPERFAMILY SSF52540 39 208 3.23E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05075 ab88792843963975e7a3227768867f2f 818 SUPERFAMILY SSF52540 238 376 3.23E-17 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS05075 ab88792843963975e7a3227768867f2f 818 Pfam PF04851 Type III restriction enzyme, res subunit 18 206 1.9E-19 T 09-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_RS05075 ab88792843963975e7a3227768867f2f 818 Gene3D G3DSA:3.40.50.300 15 210 8.4E-13 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS18160 9dd125a2501f3e83255a4c3ce46c9fea 255 Pfam PF12730 ABC-2 family transporter protein 5 176 2.9E-21 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 UA74_RS02795 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 18.93 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02795 bd9bde2b3237f8ed432d36a20c3fe2cd 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.2E-20 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02795 bd9bde2b3237f8ed432d36a20c3fe2cd 54 SUPERFAMILY SSF57829 4 54 3.6E-18 T 09-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_RS02795 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Pfam PF00471 Ribosomal protein L33 9 54 4.0E-21 T 09-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS05635 b04e62105538b0f14f7e363e6df1c462 509 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 19 437 7.2E-147 T 09-03-2017 IPR002823 Protein of unknown function DUF112, transmembrane UA74_RS29400 c9dd70767164b444a371910a05040993 125 SUPERFAMILY SSF55718 67 124 8.95E-5 T 09-03-2017 IPR003033 SCP2 sterol-binding domain UA74_RS09850 8385d8b4203133b7631be229ec154474 364 Gene3D G3DSA:1.10.10.10 1 42 1.8E-5 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14605 ada4c29ed5154541b299c07a966cb5c0 89 Gene3D G3DSA:3.40.50.720 1 74 2.8E-10 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS16215 31b8f9336269270e08741c80c8c38d92 142 Pfam PF07811 TadE-like protein 14 54 9.3E-9 T 09-03-2017 IPR012495 TadE-like UA74_RS10730 678e3816aac61cceb6c91934148a623f 288 Pfam PF08241 Methyltransferase domain 91 186 1.3E-18 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS10730 678e3816aac61cceb6c91934148a623f 288 SUPERFAMILY SSF53335 44 270 7.81E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS10730 678e3816aac61cceb6c91934148a623f 288 Gene3D G3DSA:3.40.50.150 45 272 1.9E-34 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS14120 d009a324b38ff89af78470abcc23ce22 155 SUPERFAMILY SSF53927 11 137 2.84E-22 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 UA74_RS14120 d009a324b38ff89af78470abcc23ce22 155 Gene3D G3DSA:3.40.140.10 7 138 3.7E-17 T 09-03-2017 UA74_RS14120 d009a324b38ff89af78470abcc23ce22 155 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 112 8.9E-15 T 09-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 258 287 8900.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 163 184 230.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 138 160 170.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 92 114 10.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 217 240 540.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 115 137 7800.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 185 206 1000.0 T 09-03-2017 IPR006626 Parallel beta-helix repeat UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 SUPERFAMILY SSF51126 3 333 6.91E-39 T 09-03-2017 IPR011050 Pectin lyase fold/virulence factor UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 Pfam PF13229 Right handed beta helix region 84 238 1.1E-16 T 09-03-2017 UA74_RS05860 4288718f67c82761bf83a516c72ee6d7 347 Gene3D G3DSA:2.160.20.10 11 316 7.3E-28 T 09-03-2017 IPR012334 Pectin lyase fold UA74_RS16635 46bbeb2b60d34e6159459dc7c3043574 303 Pfam PF01794 Ferric reductase like transmembrane component 57 192 5.7E-11 T 09-03-2017 IPR013130 Ferric reductase transmembrane component-like domain UA74_RS02025 9df65c11be4e6cd74d179aaa115ed7bb 255 SUPERFAMILY SSF46785 124 254 2.39E-12 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS02025 9df65c11be4e6cd74d179aaa115ed7bb 255 Gene3D G3DSA:1.10.10.10 125 254 1.6E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS00825 cbda4f08a08010ea4d4bbd195aa330b0 622 Gene3D G3DSA:2.60.40.10 50 150 2.0E-9 T 09-03-2017 IPR013783 Immunoglobulin-like fold UA74_RS00825 cbda4f08a08010ea4d4bbd195aa330b0 622 SUPERFAMILY SSF49265 58 143 3.12E-8 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS00825 cbda4f08a08010ea4d4bbd195aa330b0 622 SMART SM00060 59 139 4.3E-7 T 09-03-2017 IPR003961 Fibronectin type III GO:0005515 UA74_RS22460 06e6ac4c67c0e1e5409c07294ba13504 364 Pfam PF06224 Winged helix DNA-binding domain 31 345 4.3E-70 T 09-03-2017 IPR009351 Protein of unknown function DUF1006 UA74_RS27165 465a35666fb046714de1cb130b5c91cd 366 Pfam PF00823 PPE family 19 160 7.5E-10 T 09-03-2017 IPR000030 PPE family UA74_RS27165 465a35666fb046714de1cb130b5c91cd 366 SUPERFAMILY SSF140459 9 174 1.73E-14 T 09-03-2017 UA74_RS05495 e21efe2f84b745265b554894d60c1a65 376 Pfam PF07730 Histidine kinase 188 251 8.3E-10 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS02630 49e292ae12fafdc6c966f4d26e142e21 353 Gene3D G3DSA:3.40.50.970 36 228 4.5E-83 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02630 49e292ae12fafdc6c966f4d26e142e21 353 SUPERFAMILY SSF52518 28 350 5.16E-84 T 09-03-2017 IPR029061 Thiamin diphosphate-binding fold UA74_RS02630 49e292ae12fafdc6c966f4d26e142e21 353 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 70 217 4.1E-30 T 09-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_RS06060 7d15322ca89274c02a9ead5c8db19159 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 3.3E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS14675 1f044e4eec2145e43a4217bce0f79245 269 SUPERFAMILY SSF159713 73 248 1.44E-19 T 09-03-2017 UA74_RS14675 1f044e4eec2145e43a4217bce0f79245 269 Pfam PF04016 Putative heavy-metal chelation 140 221 1.1E-10 T 09-03-2017 IPR007161 Putative heavy-metal chelation domain UA74_RS23425 9951b5ca1190b39cb382cefd5c3d59fa 594 Gene3D G3DSA:2.130.10.130 273 358 1.8E-5 T 09-03-2017 UA74_RS23425 9951b5ca1190b39cb382cefd5c3d59fa 594 Gene3D G3DSA:2.130.10.130 91 191 1.8E-5 T 09-03-2017 UA74_RS23425 9951b5ca1190b39cb382cefd5c3d59fa 594 SUPERFAMILY SSF69318 95 365 9.94E-13 T 09-03-2017 UA74_RS29935 fa2b0db11730058f445269d37fac8a7d 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 2.4E-11 T 09-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_RS29935 fa2b0db11730058f445269d37fac8a7d 100 Gene3D G3DSA:3.30.70.900 1 93 4.1E-17 T 09-03-2017 UA74_RS29935 fa2b0db11730058f445269d37fac8a7d 100 SUPERFAMILY SSF54909 3 93 9.58E-15 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS16940 23e97230491b67f17bcc7a49324cf827 161 Pfam PF12802 MarR family 21 80 3.9E-8 T 09-03-2017 UA74_RS16940 23e97230491b67f17bcc7a49324cf827 161 SUPERFAMILY SSF46785 5 95 2.51E-10 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS16940 23e97230491b67f17bcc7a49324cf827 161 Gene3D G3DSA:1.10.10.10 4 83 5.8E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS04905 6bd1316357e1340161c50fadac963b52 376 Pfam PF00899 ThiF family 127 340 1.3E-7 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UA74_RS04905 6bd1316357e1340161c50fadac963b52 376 Gene3D G3DSA:3.40.50.720 127 342 2.8E-7 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS04905 6bd1316357e1340161c50fadac963b52 376 SUPERFAMILY SSF69572 128 344 7.19E-9 T 09-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UA74_RS08050 071c54adf9827ecf454f3ee887a0e371 209 Pfam PF01323 DSBA-like thioredoxin domain 13 167 2.1E-7 T 09-03-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 UA74_RS08050 071c54adf9827ecf454f3ee887a0e371 209 SUPERFAMILY SSF52833 11 169 2.49E-22 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS08050 071c54adf9827ecf454f3ee887a0e371 209 Gene3D G3DSA:3.40.30.10 10 167 1.4E-12 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS19970 65099a495028774995cb98689ef030f5 1126 Pfam PF13569 Domain of unknown function (DUF4132) 853 1035 5.6E-55 T 09-03-2017 IPR025406 Domain of unknown function DUF4132 UA74_RS06325 981f04b57e53eaba71ebb8d65d7e9c59 219 Gene3D G3DSA:1.20.1540.10 28 203 2.5E-14 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UA74_RS06325 981f04b57e53eaba71ebb8d65d7e9c59 219 Pfam PF01694 Rhomboid family 72 204 1.5E-20 T 09-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UA74_RS06325 981f04b57e53eaba71ebb8d65d7e9c59 219 SUPERFAMILY SSF144091 25 205 9.42E-26 T 09-03-2017 UA74_RS20985 95ef35fec5a3fff19c36f6f2d843ea94 136 Gene3D G3DSA:1.10.10.10 14 96 4.5E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS01325 f2acf4507c21d43fec5ee26a24b0e073 99 PRINTS PR01217 Proline rich extensin signature 14 30 1.4E-11 T 09-03-2017 UA74_RS01325 f2acf4507c21d43fec5ee26a24b0e073 99 PRINTS PR01217 Proline rich extensin signature 47 68 1.4E-11 T 09-03-2017 UA74_RS01325 f2acf4507c21d43fec5ee26a24b0e073 99 PRINTS PR01217 Proline rich extensin signature 35 47 1.4E-11 T 09-03-2017 UA74_RS25470 f5c20c9f39426338c511b9929f6837c5 269 Pfam PF00583 Acetyltransferase (GNAT) family 179 252 7.6E-13 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS25470 f5c20c9f39426338c511b9929f6837c5 269 Gene3D G3DSA:3.40.630.30 117 254 9.1E-26 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS25470 f5c20c9f39426338c511b9929f6837c5 269 SUPERFAMILY SSF55729 116 263 1.27E-23 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS15120 9577f781b47ea1a7282fa71d98b07b9a 588 Gene3D G3DSA:1.10.287.1060 74 124 3.1E-4 T 09-03-2017 UA74_RS15120 9577f781b47ea1a7282fa71d98b07b9a 588 SUPERFAMILY SSF140453 75 162 1.12E-7 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS25075 d9f14863b7cbaf9d7268468184323e80 132 PIRSF PIRSF017385 1 132 5.7E-49 T 09-03-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UA74_RS25075 d9f14863b7cbaf9d7268468184323e80 132 Pfam PF12270 Cytochrome c oxidase subunit IV 1 129 2.2E-51 T 09-03-2017 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UA74_RS05730 6fad308e79869010cf6f77067c535023 235 SUPERFAMILY SSF82607 12 97 2.35E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS05730 6fad308e79869010cf6f77067c535023 235 Gene3D G3DSA:3.30.1310.10 8 98 1.1E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS05730 6fad308e79869010cf6f77067c535023 235 Pfam PF02575 YbaB/EbfC DNA-binding family 14 99 1.0E-9 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS23675 1597c89eb62762d0778bfa68d51369ad 274 SUPERFAMILY SSF51658 7 263 7.07E-55 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS23675 1597c89eb62762d0778bfa68d51369ad 274 Pfam PF01261 Xylose isomerase-like TIM barrel 43 220 1.3E-30 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS23675 1597c89eb62762d0778bfa68d51369ad 274 Gene3D G3DSA:3.20.20.150 11 267 2.0E-61 T 09-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_RS16995 38941fa0b09676d81e1346b7b6fc1794 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 5 432 2.5E-10 T 09-03-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit UA74_RS03255 5e712649752df5cc8fb4a8ad0e90e79c 128 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 1.5E-20 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain UA74_RS03255 5e712649752df5cc8fb4a8ad0e90e79c 128 Pfam PF09723 Zinc ribbon domain 2 40 2.7E-14 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain UA74_RS03255 5e712649752df5cc8fb4a8ad0e90e79c 128 SMART SM00834 2 41 1.5E-14 T 09-03-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain UA74_RS27805 2fcc0e438555f71eff577ea532a288a3 1352 SUPERFAMILY SSF160424 15 142 3.79E-12 T 09-03-2017 IPR006728 Protein of unknown function DUF600 UA74_RS27805 2fcc0e438555f71eff577ea532a288a3 1352 Pfam PF14021 Protein of unknown function (DUF4237) 1258 1342 3.4E-27 T 09-03-2017 IPR025331 Protein of unknown function DUF4237 UA74_RS30385 0661d79d27684e028930730be6e36c1b 538 Gene3D G3DSA:3.20.20.70 78 200 5.2E-5 T 09-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_RS30385 0661d79d27684e028930730be6e36c1b 538 SUPERFAMILY SSF56112 33 254 6.83E-11 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS24770 983b75b5ffbd1283244801e6a1c2643b 170 SUPERFAMILY SSF55729 29 159 1.13E-14 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS24770 983b75b5ffbd1283244801e6a1c2643b 170 Gene3D G3DSA:3.40.630.30 9 167 3.4E-16 T 09-03-2017 IPR016181 Acyl-CoA N-acyltransferase UA74_RS24770 983b75b5ffbd1283244801e6a1c2643b 170 Pfam PF00583 Acetyltransferase (GNAT) family 78 145 1.7E-8 T 09-03-2017 IPR000182 GNAT domain GO:0008080 UA74_RS07405 874ee370722315e6fded366c51b242a9 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 41 5.6E-6 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS21565 c2cd35c7de6db3bdcc7f7c8ee48e2367 426 Pfam PF01757 Acyltransferase family 10 346 1.2E-10 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS16790 c61cf54f13a1b3c6362006f28bb147d7 150 Pfam PF02575 YbaB/EbfC DNA-binding family 23 104 2.9E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS16790 c61cf54f13a1b3c6362006f28bb147d7 150 SUPERFAMILY SSF82607 22 105 2.22E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS16790 c61cf54f13a1b3c6362006f28bb147d7 150 Gene3D G3DSA:3.30.1310.10 22 103 2.5E-4 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS30005 d0b752d17f44dcc36e11213bcc60d6eb 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 120 1.0E-5 T 09-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_RS30005 d0b752d17f44dcc36e11213bcc60d6eb 140 Gene3D G3DSA:3.10.180.10 3 124 1.2E-28 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS30005 d0b752d17f44dcc36e11213bcc60d6eb 140 SUPERFAMILY SSF54593 7 124 3.89E-21 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS02165 0070d4a049737a2365096e8abedb049b 62 Gene3D G3DSA:3.40.1620.10 29 49 4.4E-4 T 09-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_RS29380 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 376 391 8.8E-5 T 09-03-2017 UA74_RS29380 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 428 446 8.8E-5 T 09-03-2017 UA74_RS29380 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 312 323 8.8E-5 T 09-03-2017 UA74_RS29380 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 404 414 8.8E-5 T 09-03-2017 UA74_RS29380 8543f1a409dbe03b82ae32e502820741 474 SUPERFAMILY SSF140459 32 178 2.28E-7 T 09-03-2017 UA74_RS20555 8439f3f49f4d63942f45dd77127cc6b6 184 Gene3D G3DSA:2.30.110.10 11 166 1.2E-44 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS20555 8439f3f49f4d63942f45dd77127cc6b6 184 SMART SM00903 19 166 1.4E-41 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 UA74_RS20555 8439f3f49f4d63942f45dd77127cc6b6 184 Pfam PF01613 Flavin reductase like domain 19 167 1.1E-35 T 09-03-2017 IPR002563 Flavin reductase like domain GO:0010181 UA74_RS20555 8439f3f49f4d63942f45dd77127cc6b6 184 SUPERFAMILY SSF50475 13 167 1.13E-39 T 09-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UA74_RS19835 f796a0f4db1b1d1bc386c4b2dcfb231f 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.1E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS04770 c2d995191103a4899278678d61e74ab4 315 Pfam PF11350 Protein of unknown function (DUF3152) 101 310 2.9E-59 T 09-03-2017 IPR022603 Domain of unknown function DUF3152 UA74_RS04770 c2d995191103a4899278678d61e74ab4 315 SUPERFAMILY SSF55486 126 275 5.63E-14 T 09-03-2017 UA74_RS21585 cd10e5a192103eafa86b828d13c1c128 344 Pfam PF11382 Copper transport outer membrane protein, MctB 2 308 6.7E-84 T 09-03-2017 IPR021522 Copper transporter MctB GO:0006810 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 Gene3D G3DSA:1.20.1250.20 472 503 1.3E-20 T 09-03-2017 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 Gene3D G3DSA:1.20.1250.20 31 205 3.3E-31 T 09-03-2017 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 Gene3D G3DSA:1.20.1250.20 279 434 1.3E-20 T 09-03-2017 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 Pfam PF07690 Major Facilitator Superfamily 31 426 5.7E-46 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 1.5E-6 T 09-03-2017 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 90 112 1.5E-6 T 09-03-2017 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 417 436 1.5E-6 T 09-03-2017 UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 SUPERFAMILY SSF103473 264 436 2.35E-64 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 SUPERFAMILY SSF103473 10 211 2.35E-64 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS29765 c62481fe1e3b04bbf0b441b8aa345edb 508 SUPERFAMILY SSF103473 474 500 2.35E-64 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS20195 22afb0b73a3bee1d2dd504a85417fb33 278 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 7 117 3.0E-11 T 09-03-2017 UA74_RS20195 22afb0b73a3bee1d2dd504a85417fb33 278 Pfam PF17197 Domain of unknown function (DUF5134) 38 277 5.1E-27 T 09-03-2017 IPR033458 Protein of unknown function DUF5134 UA74_RS00495 91d4d7ef9d3ad9b4f1115086260ce354 187 Pfam PF10517 Electron transfer DM13 82 184 1.5E-24 T 09-03-2017 IPR019545 DM13 domain UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 SUPERFAMILY SSF48264 18 400 5.5E-104 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 Gene3D G3DSA:1.10.630.10 10 400 6.1E-137 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 09-03-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 Pfam PF00067 Cytochrome P450 205 264 6.4E-7 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 Pfam PF00067 Cytochrome P450 270 369 6.4E-16 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 191 213 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 290 317 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 318 333 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 156 171 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 339 348 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 272 283 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 93 104 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 139 155 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS09870 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 348 359 3.7E-59 T 09-03-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_RS20810 780329fdb36699078cb61d15e4c8668f 224 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 2 98 3.0E-25 T 09-03-2017 IPR011748 Uncharacterised protein family, phage tail-like UA74_RS20810 780329fdb36699078cb61d15e4c8668f 224 Pfam PF09684 Phage tail protein (Tail_P2_I) 11 144 9.4E-14 T 09-03-2017 IPR006521 Tail protein I UA74_RS17240 7fef5ff266f70992a8b616cc5e7e4c09 653 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 371 616 2.4E-81 T 09-03-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related UA74_RS17240 7fef5ff266f70992a8b616cc5e7e4c09 653 Pfam PF05425 Copper resistance protein D 224 319 5.0E-11 T 09-03-2017 IPR008457 Copper resistance protein D GO:0016021 UA74_RS13360 fad727e7ccac2f8438feec502c1a2560 419 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 84 - T 09-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_RS13360 fad727e7ccac2f8438feec502c1a2560 419 SUPERFAMILY SSF103473 13 406 8.89E-36 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS13360 fad727e7ccac2f8438feec502c1a2560 419 Gene3D G3DSA:1.20.1250.20 13 185 7.2E-22 T 09-03-2017 UA74_RS13360 fad727e7ccac2f8438feec502c1a2560 419 Pfam PF07690 Major Facilitator Superfamily 20 225 3.0E-20 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS13360 fad727e7ccac2f8438feec502c1a2560 419 Gene3D G3DSA:1.20.1250.20 265 403 2.2E-8 T 09-03-2017 UA74_RS00685 f0ed4cff4af179c7d8af1ce314abe6f6 315 SUPERFAMILY SSF53448 25 288 6.11E-33 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00685 f0ed4cff4af179c7d8af1ce314abe6f6 315 Gene3D G3DSA:3.90.550.10 29 230 1.4E-17 T 09-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases UA74_RS00685 f0ed4cff4af179c7d8af1ce314abe6f6 315 Pfam PF00535 Glycosyl transferase family 2 28 189 3.1E-14 T 09-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_RS07965 c1c51a8870baa631a9705fb0214814e2 1786 Gene3D G3DSA:1.25.40.10 158 336 4.2E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS26800 d15d0d83fac2874fce09382c1a776f41 116 Pfam PF12005 Protein of unknown function (DUF3499) 1 98 1.2E-45 T 09-03-2017 IPR021888 Protein of unknown function DUF3499 UA74_RS04585 4a4dd401185b4c1d4fecfe1d457362f8 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 52 2.3E-29 T 09-03-2017 IPR021465 Protein of unknown function DUF3117 UA74_RS29055 90af348d589cc1fabed2d38835ab5d38 129 Pfam PF12986 Domain of unknown function (DUF3870) 24 112 2.4E-21 T 09-03-2017 IPR024617 Domain of unknown function DUF3870 UA74_RS23055 d4fe028df7cf978505264492d5cee73c 200 Gene3D G3DSA:3.40.50.300 18 192 4.6E-12 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS23055 d4fe028df7cf978505264492d5cee73c 200 Pfam PF03029 Conserved hypothetical ATP binding protein 23 190 8.7E-24 T 09-03-2017 IPR004130 GPN-loop GTPase UA74_RS23055 d4fe028df7cf978505264492d5cee73c 200 SUPERFAMILY SSF52540 19 191 5.34E-20 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS19080 b2380bc52a6aa5b5497bd303812e1b8d 332 Pfam PF01497 Periplasmic binding protein 56 306 5.8E-23 T 09-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 UA74_RS19080 b2380bc52a6aa5b5497bd303812e1b8d 332 SUPERFAMILY SSF53807 52 327 2.0E-39 T 09-03-2017 UA74_RS19080 b2380bc52a6aa5b5497bd303812e1b8d 332 Gene3D G3DSA:3.40.50.1980 52 194 3.6E-5 T 09-03-2017 UA74_RS19080 b2380bc52a6aa5b5497bd303812e1b8d 332 Gene3D G3DSA:3.40.50.1980 197 327 2.2E-31 T 09-03-2017 UA74_RS17755 614649165a97765f2ba65d26607710e3 395 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 6 340 7.0E-93 T 09-03-2017 IPR010148 CRISPR-associated protein, CT1975 UA74_RS17755 614649165a97765f2ba65d26607710e3 395 Pfam PF09344 CT1975-like protein 7 355 1.8E-100 T 09-03-2017 IPR010148 CRISPR-associated protein, CT1975 UA74_RS12175 fd662357629eab36108d1b1096db6e50 151 Pfam PF14430 Immunity protein Imm1 14 145 1.2E-14 T 09-03-2017 IPR025680 Immunity protein Imm1 UA74_RS18575 1b90577d1a035d0c5c9732724dc9a302 422 Pfam PF10544 T5orf172 domain 301 388 1.6E-12 T 09-03-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding UA74_RS18575 1b90577d1a035d0c5c9732724dc9a302 422 SMART SM00974 311 394 9.5E-26 T 09-03-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding UA74_RS18575 1b90577d1a035d0c5c9732724dc9a302 422 Pfam PF13250 Domain of unknown function (DUF4041) 151 206 4.8E-16 T 09-03-2017 IPR025280 Domain of unknown function DUF4041 UA74_RS14335 524c5e905e4b8e4017973761a397233d 460 Gene3D G3DSA:3.40.50.720 86 151 2.7E-6 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS14335 524c5e905e4b8e4017973761a397233d 460 SUPERFAMILY SSF51735 73 152 6.63E-7 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 Gene3D G3DSA:3.40.50.150 1185 1265 9.8E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 Gene3D G3DSA:3.40.50.150 595 657 9.8E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 Gene3D G3DSA:3.40.50.150 1116 1140 9.8E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 Gene3D G3DSA:3.40.50.150 689 733 9.8E-22 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 SUPERFAMILY SSF53335 1197 1267 5.72E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 SUPERFAMILY SSF53335 326 388 5.72E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 SUPERFAMILY SSF53335 434 519 5.72E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 SUPERFAMILY SSF53335 584 735 5.72E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS19205 f5face286ed835146108c2f47b92c05f 1813 SUPERFAMILY SSF53335 1122 1144 5.72E-36 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS28450 26bda330724643f5285ff987f562c7ef 339 Gene3D G3DSA:3.30.1330.60 248 320 4.3E-7 T 09-03-2017 IPR006665 OmpA-like domain UA74_RS28450 26bda330724643f5285ff987f562c7ef 339 Pfam PF00691 OmpA family 252 317 3.0E-5 T 09-03-2017 IPR006665 OmpA-like domain UA74_RS28450 26bda330724643f5285ff987f562c7ef 339 SUPERFAMILY SSF103088 243 320 1.12E-7 T 09-03-2017 IPR006665 OmpA-like domain UA74_RS29455 9ee223e5b1bf8162020e262b83a47f6b 266 Pfam PF14011 EspG family 20 257 3.1E-51 T 09-03-2017 IPR025734 EspG family UA74_RS10100 11e73db26b0231145a29a290e0ece8bb 138 Gene3D G3DSA:1.10.10.10 8 137 3.6E-11 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10100 11e73db26b0231145a29a290e0ece8bb 138 SUPERFAMILY SSF46785 8 137 8.25E-13 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS13095 dd5ccdf99be52417af23ada9dcd2ca9a 191 Pfam PF04186 FxsA cytoplasmic membrane protein 3 106 6.2E-25 T 09-03-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 UA74_RS00845 671eb3ed2a8a637bebebc07dcda6b186 71 SUPERFAMILY SSF69047 5 66 7.45E-9 T 09-03-2017 IPR008462 CsbD-like UA74_RS00845 671eb3ed2a8a637bebebc07dcda6b186 71 Gene3D G3DSA:1.10.1470.10 5 67 1.4E-14 T 09-03-2017 IPR008462 CsbD-like UA74_RS00845 671eb3ed2a8a637bebebc07dcda6b186 71 Pfam PF05532 CsbD-like 5 56 2.7E-14 T 09-03-2017 IPR008462 CsbD-like UA74_RS25880 92e73f219225ef43de97c13f88849dab 304 Gene3D G3DSA:3.40.50.1820 23 300 5.0E-67 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25880 92e73f219225ef43de97c13f88849dab 304 SUPERFAMILY SSF53474 32 299 3.27E-50 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS25880 92e73f219225ef43de97c13f88849dab 304 Pfam PF07859 alpha/beta hydrolase fold 71 278 1.7E-51 T 09-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 UA74_RS05035 041e8c85742e1b1979277c61c2336141 264 Pfam PF13462 Thioredoxin 84 249 5.1E-19 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS05035 041e8c85742e1b1979277c61c2336141 264 Gene3D G3DSA:3.40.30.10 85 247 1.0E-25 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS05035 041e8c85742e1b1979277c61c2336141 264 SUPERFAMILY SSF52833 82 259 1.12E-26 T 09-03-2017 IPR012336 Thioredoxin-like fold UA74_RS11460 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 Gene3D G3DSA:2.60.200.20 49 143 3.1E-30 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS11460 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 Pfam PF00498 FHA domain 74 136 1.9E-19 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS11460 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 SUPERFAMILY SSF49879 37 143 2.3E-32 T 09-03-2017 IPR008984 SMAD/FHA domain GO:0005515 UA74_RS11460 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 SMART SM00240 72 122 2.0E-16 T 09-03-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_RS03235 ea6e1450683d90d846e68740e70c8094 74 Pfam PF14013 MT0933-like antitoxin protein 5 62 3.2E-9 T 09-03-2017 IPR028037 Antitoxin Rv0909/MT0933 UA74_RS14385 d329debbfbefdbd9d5f0f123e155c45a 229 SUPERFAMILY SSF81296 32 228 1.06E-31 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS14385 d329debbfbefdbd9d5f0f123e155c45a 229 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 226 5.9E-34 T 09-03-2017 IPR004302 Chitin-binding protein, N-terminal UA74_RS14385 d329debbfbefdbd9d5f0f123e155c45a 229 Gene3D G3DSA:2.70.50.50 32 228 2.2E-38 T 09-03-2017 UA74_RS26565 1cd0437f37071c3474f010e834bd6cb7 223 SUPERFAMILY SSF161098 18 203 7.59E-27 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS26565 1cd0437f37071c3474f010e834bd6cb7 223 Gene3D G3DSA:1.10.3720.10 17 213 4.5E-22 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS26565 1cd0437f37071c3474f010e834bd6cb7 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 212 5.6E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS07700 e9b1a310a02233281bad4002025b70da 609 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 154 495 3.9E-19 T 09-03-2017 UA74_RS07700 e9b1a310a02233281bad4002025b70da 609 Gene3D G3DSA:1.50.10.10 106 523 2.9E-59 T 09-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 UA74_RS07700 e9b1a310a02233281bad4002025b70da 609 SUPERFAMILY SSF48208 106 525 2.11E-55 T 09-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 UA74_RS23050 ae8ab7a3e13bc9a6dfa97781b7d7a718 123 Pfam PF05331 Protein of unknown function (DUF742) 11 123 6.6E-29 T 09-03-2017 IPR007995 Protein of unknown function DUF742 UA74_RS20295 c77b9a89b6ae722d1d33fbaa797ab082 65 Pfam PF04149 Domain of unknown function (DUF397) 10 60 3.8E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS29575 e8d2f900437ef52dc18d3318929460d0 276 SMART SM00530 16 71 2.7E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS29575 e8d2f900437ef52dc18d3318929460d0 276 Pfam PF13560 Helix-turn-helix domain 12 73 1.4E-11 T 09-03-2017 UA74_RS29575 e8d2f900437ef52dc18d3318929460d0 276 Gene3D G3DSA:1.10.260.40 6 68 3.3E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS29575 e8d2f900437ef52dc18d3318929460d0 276 SUPERFAMILY SSF47413 11 70 4.83E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS03555 91c9f1262ef1f593509c8b8c93b0168d 228 Gene3D G3DSA:1.10.3720.10 16 221 6.9E-36 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03555 91c9f1262ef1f593509c8b8c93b0168d 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 223 3.0E-24 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS03555 91c9f1262ef1f593509c8b8c93b0168d 228 SUPERFAMILY SSF161098 16 212 2.88E-38 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS08010 2d2dbda81da93523f8d86ff4a470234e 209 Pfam PF12079 Protein of unknown function (DUF3558) 17 204 5.8E-25 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS22540 45c5a70ebebcd21aaed0bd82848218d6 155 Gene3D G3DSA:3.90.79.10 2 152 1.8E-28 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS22540 45c5a70ebebcd21aaed0bd82848218d6 155 SUPERFAMILY SSF55811 4 154 2.03E-20 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS22540 45c5a70ebebcd21aaed0bd82848218d6 155 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 09-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_RS22540 45c5a70ebebcd21aaed0bd82848218d6 155 Pfam PF00293 NUDIX domain 6 148 1.2E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS04715 8d7cec6638bdf446ade69f3f53dc72e6 189 Pfam PF03703 Bacterial PH domain 79 137 7.5E-12 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS12170 337b995139667b3393e44037d7e91f1e 267 Pfam PF14428 SCP1.201-like deaminase 142 264 3.0E-18 T 09-03-2017 IPR032724 Deaminase, SCP1.201-like UA74_RS14160 1b269a1e8670b74f2e5bed8409eca1fd 271 Pfam PF13349 Putative adhesin 139 246 7.3E-9 T 09-03-2017 IPR025164 Putative adhesin UA74_RS10810 63be363233e34ce20dafee9d37ffca1d 224 SMART SM00953 66 196 1.4E-5 T 09-03-2017 IPR014914 RES domain UA74_RS10810 63be363233e34ce20dafee9d37ffca1d 224 Pfam PF08808 RES domain 32 202 1.7E-19 T 09-03-2017 IPR014914 RES domain UA74_RS29370 5b9d1c3ee91575aa5805af09b29a5dbd 209 Pfam PF12079 Protein of unknown function (DUF3558) 18 203 2.8E-23 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS08500 605fb9274439723f2db27d03cf690528 259 Gene3D G3DSA:3.40.50.300 4 236 1.8E-64 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08500 605fb9274439723f2db27d03cf690528 259 SUPERFAMILY SSF52540 5 234 9.53E-61 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS08500 605fb9274439723f2db27d03cf690528 259 Pfam PF00005 ABC transporter 23 174 8.1E-30 T 09-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_RS08500 605fb9274439723f2db27d03cf690528 259 SMART SM00382 32 230 3.0E-14 T 09-03-2017 IPR003593 AAA+ ATPase domain UA74_RS00410 b1dcff9e635582cd38dedd14c0d07a64 592 Pfam PF00474 Sodium:solute symporter family 295 486 8.6E-15 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS00410 b1dcff9e635582cd38dedd14c0d07a64 592 Pfam PF00474 Sodium:solute symporter family 22 190 4.6E-28 T 09-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS02085 fd3593e9338410cfc8325a241a0fa8eb 369 Gene3D G3DSA:3.40.50.2000 2 192 1.5E-56 T 09-03-2017 UA74_RS02085 fd3593e9338410cfc8325a241a0fa8eb 369 SUPERFAMILY SSF53756 2 359 2.23E-83 T 09-03-2017 UA74_RS02085 fd3593e9338410cfc8325a241a0fa8eb 369 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 351 8.2E-79 T 09-03-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_RS02085 fd3593e9338410cfc8325a241a0fa8eb 369 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 353 5.2E-81 T 09-03-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 UA74_RS02085 fd3593e9338410cfc8325a241a0fa8eb 369 Gene3D G3DSA:3.40.50.2000 193 353 1.6E-37 T 09-03-2017 UA74_RS29910 b7a8cd35f647df1b8d27c90b4c789ac0 285 Gene3D G3DSA:2.60.40.230 61 188 1.1E-17 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS29910 b7a8cd35f647df1b8d27c90b4c789ac0 285 SUPERFAMILY SSF49319 63 188 2.29E-12 T 09-03-2017 IPR027273 Neocarzinostatin-like UA74_RS14795 991fe44ad9d403dbfa7d1adeda6da2d8 335 Pfam PF08279 HTH domain 4 59 2.1E-11 T 09-03-2017 IPR013196 Helix-turn-helix, type 11 UA74_RS14795 991fe44ad9d403dbfa7d1adeda6da2d8 335 ProSitePatterns PS00894 DeoR-type HTH domain signature. 4 38 - T 09-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_RS14795 991fe44ad9d403dbfa7d1adeda6da2d8 335 Pfam PF13280 WYL domain 138 313 2.3E-22 T 09-03-2017 IPR026881 WYL domain UA74_RS14795 991fe44ad9d403dbfa7d1adeda6da2d8 335 SUPERFAMILY SSF46785 4 61 4.15E-9 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS14795 991fe44ad9d403dbfa7d1adeda6da2d8 335 Gene3D G3DSA:1.10.10.10 3 62 1.5E-16 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09545 75113602b9e0586cdec824a9dda93ced 405 Pfam PF06224 Winged helix DNA-binding domain 37 383 2.3E-77 T 09-03-2017 IPR009351 Protein of unknown function DUF1006 UA74_RS28315 c8cbc1f39074539f25bde7a2cae730c4 187 Pfam PF14016 Protein of unknown function (DUF4232) 52 179 4.5E-26 T 09-03-2017 IPR025326 Protein of unknown function DUF4232 UA74_RS25700 00e42ee0df7606799d348336a7acc631 91 Pfam PF04149 Domain of unknown function (DUF397) 9 59 4.8E-22 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS21160 45c177ef99d175d9d2404e201238a8e9 603 Pfam PF02652 L-lactate permease 15 292 5.1E-74 T 09-03-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 UA74_RS21160 45c177ef99d175d9d2404e201238a8e9 603 Pfam PF02652 L-lactate permease 335 593 2.3E-66 T 09-03-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 UA74_RS25245 d5b2069760a953a4d320e37a239124ad 242 Pfam PF13829 Domain of unknown function (DUF4191) 19 234 1.6E-85 T 09-03-2017 IPR025445 Protein of unknown function DUF4191 UA74_RS25245 d5b2069760a953a4d320e37a239124ad 242 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 28 227 8.0E-68 T 09-03-2017 UA74_RS07425 f32b73307deba15398249cc6d86fc8f8 301 Pfam PF14100 Methane oxygenase PmoA 20 293 6.7E-65 T 09-03-2017 IPR029475 Methane oxygenase PmoA UA74_RS24585 e4700718ea9a07d75988916cafa93651 109 SUPERFAMILY SSF53927 7 79 7.52E-10 T 09-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 UA74_RS24585 e4700718ea9a07d75988916cafa93651 109 Gene3D G3DSA:3.40.140.10 22 76 7.5E-7 T 09-03-2017 UA74_RS23385 0f87ee8393ce061f2d691d7010a7bedf 424 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 277 402 5.7E-26 T 09-03-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 UA74_RS23385 0f87ee8393ce061f2d691d7010a7bedf 424 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 260 8.5E-89 T 09-03-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 UA74_RS00205 4f6ceb11ca01f17f2e730bb426f0d273 304 Pfam PF01636 Phosphotransferase enzyme family 46 243 1.3E-18 T 09-03-2017 IPR002575 Aminoglycoside phosphotransferase UA74_RS00205 4f6ceb11ca01f17f2e730bb426f0d273 304 SUPERFAMILY SSF56112 22 271 3.79E-32 T 09-03-2017 IPR011009 Protein kinase-like domain UA74_RS00205 4f6ceb11ca01f17f2e730bb426f0d273 304 Gene3D G3DSA:3.90.1200.10 118 264 1.7E-18 T 09-03-2017 UA74_RS21280 e3b25debb41183711df72be87b2f4e91 241 Pfam PF07103 Protein of unknown function (DUF1365) 5 231 2.3E-58 T 09-03-2017 IPR010775 Protein of unknown function DUF1365 UA74_RS14850 439b9848d1d62cadbfe2a856b54f46a6 243 SUPERFAMILY SSF54593 117 228 5.48E-11 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS14850 439b9848d1d62cadbfe2a856b54f46a6 243 Gene3D G3DSA:3.10.180.10 116 223 8.0E-16 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS17270 bfa4b7fd386f8445f67b1bba80b67254 421 SUPERFAMILY SSF69318 79 195 1.88E-7 T 09-03-2017 UA74_RS17270 bfa4b7fd386f8445f67b1bba80b67254 421 SUPERFAMILY SSF69318 336 371 1.88E-7 T 09-03-2017 UA74_RS00455 849377488ca519c4afac5a2dcd050667 268 Pfam PF14011 EspG family 11 256 9.3E-44 T 09-03-2017 IPR025734 EspG family UA74_RS03295 1f19e630bb18816b056168f77622c1b4 198 Gene3D G3DSA:3.10.180.10 3 128 1.4E-23 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS03295 1f19e630bb18816b056168f77622c1b4 198 SUPERFAMILY SSF54593 5 125 1.97E-17 T 09-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_RS30150 f49a2ba02f216f79a1f0f2b1750cd65b 529 PIRSF PIRSF010361 18 497 2.3E-168 T 09-03-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane UA74_RS30150 f49a2ba02f216f79a1f0f2b1750cd65b 529 Pfam PF09594 Protein of unknown function (DUF2029) 168 393 2.6E-15 T 09-03-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 UA74_RS19040 4bfcbcd315457e63c8f348da1e24217f 183 SUPERFAMILY SSF81301 6 166 8.83E-45 T 09-03-2017 UA74_RS19040 4bfcbcd315457e63c8f348da1e24217f 183 Pfam PF04229 GrpB protein 5 164 2.7E-47 T 09-03-2017 IPR007344 GrpB/Dephospho-CoA kinase UA74_RS19040 4bfcbcd315457e63c8f348da1e24217f 183 Gene3D G3DSA:3.30.460.10 2 168 1.1E-50 T 09-03-2017 UA74_RS19325 23016696f079236469ff55c479d15bfd 352 Pfam PF01757 Acyltransferase family 9 316 3.1E-19 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS06040 316ecf0c5d59738b493a62f19c1416aa 166 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 160 6.1E-59 T 09-03-2017 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger UA74_RS26460 cb13c0913afebdb569e8da49b5240b19 295 Pfam PF12679 ABC-2 family transporter protein 71 294 1.2E-9 T 09-03-2017 IPR032688 ABC-2 family transporter protein GO:0006810 UA74_RS12760 f476a5112148fd1d269cce166585b64f 199 Gene3D G3DSA:1.10.357.10 6 169 8.7E-18 T 09-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 UA74_RS12760 f476a5112148fd1d269cce166585b64f 199 SUPERFAMILY SSF46689 2 74 3.59E-10 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS06055 a929a4f8e216f60c6e1152ab0e24834c 250 PIRSF PIRSF006648 1 250 7.6E-50 T 09-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 UA74_RS06055 a929a4f8e216f60c6e1152ab0e24834c 250 Pfam PF01061 ABC-2 type transporter 10 215 1.1E-31 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS01390 43707936c7e581d64393a46e4cd80758 213 SMART SM00943 19 181 5.5E-11 T 09-03-2017 IPR015330 DNA primase/polymerase, bifunctional, N-terminal UA74_RS16205 383231774eae2e81e3b7e1a2ce95a944 297 Pfam PF00482 Type II secretion system (T2SS), protein F 161 288 4.7E-9 T 09-03-2017 IPR018076 Type II secretion system F domain UA74_RS28780 4250a771bddd0030e3b7befc50309f73 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 78 1.2E-15 T 09-03-2017 IPR005149 Transcription regulator PadR, N-terminal UA74_RS28780 4250a771bddd0030e3b7befc50309f73 174 Gene3D G3DSA:1.10.10.10 1 87 2.5E-25 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS28780 4250a771bddd0030e3b7befc50309f73 174 SUPERFAMILY SSF46785 4 166 4.68E-33 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS22970 7107c760175876abecd19918335669fc 523 SUPERFAMILY SSF103473 471 498 3.14E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22970 7107c760175876abecd19918335669fc 523 SUPERFAMILY SSF103473 8 205 3.14E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22970 7107c760175876abecd19918335669fc 523 SUPERFAMILY SSF103473 252 423 3.14E-59 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS22970 7107c760175876abecd19918335669fc 523 Pfam PF07690 Major Facilitator Superfamily 26 413 2.7E-46 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS22970 7107c760175876abecd19918335669fc 523 Gene3D G3DSA:1.20.1250.20 274 424 2.9E-14 T 09-03-2017 UA74_RS22970 7107c760175876abecd19918335669fc 523 Gene3D G3DSA:1.20.1250.20 19 199 4.5E-27 T 09-03-2017 UA74_RS22970 7107c760175876abecd19918335669fc 523 Gene3D G3DSA:1.20.1250.20 473 496 2.9E-14 T 09-03-2017 UA74_RS27035 f9859b290c6676438125e18cb04fd2d3 840 Pfam PF14021 Protein of unknown function (DUF4237) 733 816 1.6E-24 T 09-03-2017 IPR025331 Protein of unknown function DUF4237 UA74_RS20570 bc1b998e32369b37520853017afb0e24 224 Gene3D G3DSA:3.60.20.10 1 213 6.0E-62 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS20570 bc1b998e32369b37520853017afb0e24 224 SUPERFAMILY SSF56235 1 223 7.25E-64 T 09-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_RS20570 bc1b998e32369b37520853017afb0e24 224 Pfam PF06267 Family of unknown function (DUF1028) 2 191 5.9E-55 T 09-03-2017 IPR010430 Protein of unknown function DUF1028 UA74_RS25280 73eff81367b7f6cfea30918999e0cba9 252 Pfam PF00117 Glutamine amidotransferase class-I 22 186 2.9E-18 T 09-03-2017 IPR017926 Glutamine amidotransferase UA74_RS25280 73eff81367b7f6cfea30918999e0cba9 252 SUPERFAMILY SSF52317 4 201 3.7E-39 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS25280 73eff81367b7f6cfea30918999e0cba9 252 Gene3D G3DSA:3.40.50.880 3 230 8.0E-50 T 09-03-2017 IPR029062 Class I glutamine amidotransferase-like UA74_RS21575 52f3e26036d8c92e1f8f6d552ddc0c02 213 Pfam PF00293 NUDIX domain 47 160 8.0E-14 T 09-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_RS21575 52f3e26036d8c92e1f8f6d552ddc0c02 213 Gene3D G3DSA:3.90.79.10 12 183 7.8E-52 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS21575 52f3e26036d8c92e1f8f6d552ddc0c02 213 SUPERFAMILY SSF55811 12 183 7.85E-43 T 09-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 UA74_RS02250 a05d2b68c7a845b38b1597630febe4c7 33 SMART SM01155 1 33 1.4E-7 T 09-03-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS02250 a05d2b68c7a845b38b1597630febe4c7 33 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 33 1.8E-11 T 09-03-2017 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_RS00590 fabb8da678b597ef5de26f00127e77d0 417 Pfam PF13845 Septum formation 140 319 1.6E-51 T 09-03-2017 IPR026004 Septum formation-related domain UA74_RS00590 fabb8da678b597ef5de26f00127e77d0 417 Pfam PF13845 Septum formation 61 107 4.8E-9 T 09-03-2017 IPR026004 Septum formation-related domain UA74_RS14315 08686321a46e6732f7332cfd7960af03 204 Pfam PF01183 Glycosyl hydrolases family 25 6 183 7.6E-31 T 09-03-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 UA74_RS14315 08686321a46e6732f7332cfd7960af03 204 SMART SM00641 3 109 2.8E-4 T 09-03-2017 IPR018077 Glycoside hydrolase, family 25 subgroup UA74_RS14315 08686321a46e6732f7332cfd7960af03 204 SUPERFAMILY SSF51445 2 195 7.72E-41 T 09-03-2017 IPR017853 Glycoside hydrolase superfamily UA74_RS14315 08686321a46e6732f7332cfd7960af03 204 Gene3D G3DSA:3.20.20.80 4 194 3.4E-46 T 09-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 UA74_RS18700 60832ee3dd0409f57d13e2863d71db2d 324 Pfam PF08012 Protein of unknown function (DUF1702) 5 318 6.9E-133 T 09-03-2017 IPR012964 Protein of unknown function DUF1702 UA74_RS29150 d619dcb280ffcc6de5b675eb3c5e55f2 96 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 17 64 3.7E-9 T 09-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_RS29150 d619dcb280ffcc6de5b675eb3c5e55f2 96 Pfam PF12728 Helix-turn-helix domain 17 65 8.1E-11 T 09-03-2017 UA74_RS26165 59b00192713968aac10085c2a111ce47 66 Pfam PF04149 Domain of unknown function (DUF397) 12 64 1.6E-20 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS03830 df3a8a503da254b7706253f1570604fa 271 SUPERFAMILY SSF63817 121 266 2.43E-9 T 09-03-2017 IPR023365 Sortase domain UA74_RS03830 df3a8a503da254b7706253f1570604fa 271 Pfam PF04203 Sortase family 169 267 6.4E-8 T 09-03-2017 IPR005754 Sortase family UA74_RS03830 df3a8a503da254b7706253f1570604fa 271 Gene3D G3DSA:2.40.260.10 173 266 2.3E-4 T 09-03-2017 IPR023365 Sortase domain UA74_RS03460 330f9ab3f70c59ab913c8fe4c29b2cb5 115 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 40 91 7.0E-11 T 09-03-2017 IPR026496 Putative ATP-grasp target RiPP UA74_RS22615 8803553d8ecc46cd47e62a4604578feb 323 SUPERFAMILY SSF56059 135 311 3.03E-16 T 09-03-2017 UA74_RS24300 84e0eaa373e9f71358321884be28dbf5 184 SUPERFAMILY SSF50370 37 175 1.81E-16 T 09-03-2017 IPR000772 Ricin B, lectin domain UA74_RS24300 84e0eaa373e9f71358321884be28dbf5 184 Gene3D G3DSA:2.80.10.50 41 175 1.5E-13 T 09-03-2017 UA74_RS00450 4723f8e4d5eba411e11be525e651727e 321 SUPERFAMILY SSF103642 21 39 1.8E-5 T 09-03-2017 UA74_RS00450 4723f8e4d5eba411e11be525e651727e 321 Gene3D G3DSA:3.10.450.50 22 40 3.8E-5 T 09-03-2017 IPR032710 NTF2-like domain UA74_RS03400 9c1b3cf249abef4061391944ad5f842d 407 Pfam PF04235 Protein of unknown function (DUF418) 240 405 3.2E-29 T 09-03-2017 IPR007349 Domain of unknown function DUF418 UA74_RS17925 0b472b86c2c404896308a1dd4fb7e633 249 Pfam PF10067 Predicted membrane protein (DUF2306) 67 216 8.0E-38 T 09-03-2017 IPR018750 Protein of unknown function DUF2306, membrane UA74_RS17830 5f54adc2d7e54df8ad24200dca6ed513 429 Gene3D G3DSA:3.40.50.620 274 386 1.9E-20 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS17830 5f54adc2d7e54df8ad24200dca6ed513 429 Gene3D G3DSA:3.40.50.620 15 169 1.9E-20 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS17830 5f54adc2d7e54df8ad24200dca6ed513 429 SUPERFAMILY SSF52402 266 382 5.42E-28 T 09-03-2017 UA74_RS17830 5f54adc2d7e54df8ad24200dca6ed513 429 SUPERFAMILY SSF52402 16 165 5.42E-28 T 09-03-2017 UA74_RS17830 5f54adc2d7e54df8ad24200dca6ed513 429 Pfam PF00733 Asparagine synthase 19 409 8.4E-26 T 09-03-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UA74_RS00585 14c878ada1c147459abbfac72b6b5236 116 Pfam PF06262 Zinicin-like metallopeptidase 29 115 8.3E-34 T 09-03-2017 IPR010428 Zinicin-like metallopeptidase UA74_RS00585 14c878ada1c147459abbfac72b6b5236 116 SUPERFAMILY SSF55486 3 115 8.61E-40 T 09-03-2017 UA74_RS04875 8830f94d8fb57537a7523fdc04aa0afa 123 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 100 110 - T 09-03-2017 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 UA74_RS04875 8830f94d8fb57537a7523fdc04aa0afa 123 Pfam PF02467 Transcription factor WhiB 41 90 1.1E-15 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS04875 8830f94d8fb57537a7523fdc04aa0afa 123 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 26 104 16.03 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS08415 178c1da6bad9a0f41e05f1cb1eee1d67 80 Gene3D G3DSA:1.10.1220.10 7 48 3.3E-6 T 09-03-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 UA74_RS08415 178c1da6bad9a0f41e05f1cb1eee1d67 80 SUPERFAMILY SSF47598 4 49 7.78E-9 T 09-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 UA74_RS17950 160a68eb5ae2a3574975385f3e88d1ee 642 Gene3D G3DSA:3.40.50.1820 337 633 4.4E-83 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17950 160a68eb5ae2a3574975385f3e88d1ee 642 Gene3D G3DSA:2.120.10.30 16 261 8.0E-23 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS17950 160a68eb5ae2a3574975385f3e88d1ee 642 SUPERFAMILY SSF69322 22 362 1.31E-20 T 09-03-2017 UA74_RS17950 160a68eb5ae2a3574975385f3e88d1ee 642 Pfam PF00326 Prolyl oligopeptidase family 420 634 3.5E-43 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS17950 160a68eb5ae2a3574975385f3e88d1ee 642 SUPERFAMILY SSF53474 303 636 8.99E-71 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS17380 9f47175440621e79589fec32b8d64155 251 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 177 249 6.4E-34 T 09-03-2017 IPR020955 Uncharacterised protein family Atu4866 UA74_RS17380 9f47175440621e79589fec32b8d64155 251 Gene3D G3DSA:2.30.40.10 21 93 7.3E-10 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS17380 9f47175440621e79589fec32b8d64155 251 SUPERFAMILY SSF51338 25 142 5.76E-10 T 09-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 UA74_RS04865 56c98e8ac3659b871c320d589de1df4f 336 Pfam PF04235 Protein of unknown function (DUF418) 176 326 8.8E-31 T 09-03-2017 IPR007349 Domain of unknown function DUF418 UA74_RS08000 11177131b9c99afea30d3fce20033204 259 Pfam PF14011 EspG family 10 252 1.1E-60 T 09-03-2017 IPR025734 EspG family UA74_RS03475 c775907cd2c57def589a36a1563f58df 66 Pfam PF04149 Domain of unknown function (DUF397) 11 61 1.9E-16 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS01160 6c99245f06807982d216ea3ed8a647d0 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 2 75 18.376 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS01160 6c99245f06807982d216ea3ed8a647d0 100 Pfam PF02467 Transcription factor WhiB 8 70 2.0E-23 T 09-03-2017 IPR003482 Transcription factor WhiB UA74_RS00765 0b7659b5b01ef7f48014dce40b411e73 74 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 7 65 1.6E-12 T 09-03-2017 IPR018691 Protein of unknown function DUF2188 UA74_RS17655 cba9779bc76d0173d768000a16591045 97 SUPERFAMILY SSF47336 12 80 9.95E-13 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17655 cba9779bc76d0173d768000a16591045 97 Gene3D G3DSA:1.10.1200.10 14 83 3.9E-15 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS17655 cba9779bc76d0173d768000a16591045 97 Pfam PF00550 Phosphopantetheine attachment site 16 80 1.2E-12 T 09-03-2017 IPR009081 Phosphopantetheine binding ACP domain UA74_RS26795 0eb21d983b9f4696c3f383d6247e2d77 158 SUPERFAMILY SSF55486 35 155 5.86E-24 T 09-03-2017 UA74_RS26795 0eb21d983b9f4696c3f383d6247e2d77 158 Pfam PF06262 Zinicin-like metallopeptidase 61 153 3.1E-10 T 09-03-2017 IPR010428 Zinicin-like metallopeptidase UA74_RS18155 370b2c9d4c152890d05ee5011231691a 321 Pfam PF01794 Ferric reductase like transmembrane component 88 212 7.2E-12 T 09-03-2017 IPR013130 Ferric reductase transmembrane component-like domain UA74_RS15755 50c78dfbfcea185a634d88e09c29a38f 533 Gene3D G3DSA:1.10.260.40 18 60 4.5E-5 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS22585 21c0f8591c5badc4183c93285717e23c 274 Pfam PF07920 Protein of unknown function (DUF1684) 124 264 2.9E-35 T 09-03-2017 IPR012467 Protein of unknown function DUF1684 UA74_RS05525 88739a4663e84956aa614147574fd0e4 114 SUPERFAMILY SSF140453 12 104 7.59E-5 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS18045 0a1e8fd4b12139cc327bc3b7f1a17c5e 292 Pfam PF04116 Fatty acid hydroxylase superfamily 98 229 2.2E-25 T 09-03-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 UA74_RS24850 13e7ee69d845bb0bbc560987fce9cd49 361 SMART SM00701 162 320 1.5E-8 T 09-03-2017 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 UA74_RS24850 13e7ee69d845bb0bbc560987fce9cd49 361 Gene3D G3DSA:3.40.80.10 158 358 1.1E-40 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS24850 13e7ee69d845bb0bbc560987fce9cd49 361 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 184 342 1.9E-11 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS24850 13e7ee69d845bb0bbc560987fce9cd49 361 SUPERFAMILY SSF55846 164 356 8.06E-39 T 09-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 UA74_RS13030 0e902c547ec263e3145967b3d2fd14f8 70 Pfam PF16827 zinc-finger 4 58 1.5E-8 T 09-03-2017 IPR031795 Putative zinc-finger containing protein UA74_RS15195 3630221434a6fb00ade616a67466d884 382 Gene3D G3DSA:1.20.120.20 84 118 7.0E-5 T 09-03-2017 UA74_RS15195 3630221434a6fb00ade616a67466d884 382 Gene3D G3DSA:1.20.120.20 173 254 7.0E-5 T 09-03-2017 UA74_RS09845 29a2184a694a49993d2d4a845fbf15cb 601 Pfam PF03703 Bacterial PH domain 91 171 3.9E-11 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS27365 32a3792a8e609de172fc19dde496b7c7 169 Pfam PF03703 Bacterial PH domain 76 154 8.4E-15 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS25020 68b80286ce2acded6ca10f4d9c265b99 473 Pfam PF05991 YacP-like NYN domain 353 470 1.1E-19 T 09-03-2017 IPR010298 Protein of unknown function DUF901 UA74_RS24725 85150cd791a31b4d251a2557a25b2e55 251 Pfam PF14325 Domain of unknown function (DUF4383) 18 132 7.7E-12 T 09-03-2017 IPR025492 Protein of unknown function DUF4383 UA74_RS16200 3831599d69f07c217332340f812c5bf5 290 Pfam PF00482 Type II secretion system (T2SS), protein F 103 228 1.6E-5 T 09-03-2017 IPR018076 Type II secretion system F domain UA74_RS02050 31ae67cffce45354ceacc0855521e2e3 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 6.2E-15 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS18180 325cfeda5296f93826fcd1058e1d76c7 402 Pfam PF07730 Histidine kinase 196 261 6.9E-17 T 09-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_RS18180 325cfeda5296f93826fcd1058e1d76c7 402 SUPERFAMILY SSF55874 278 397 7.17E-15 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS18180 325cfeda5296f93826fcd1058e1d76c7 402 Gene3D G3DSA:3.30.565.10 309 399 5.8E-6 T 09-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain UA74_RS14480 128636ce11016ae68f4c2a48feb166db 390 PIRSF PIRSF035009 1 384 4.4E-133 T 09-03-2017 IPR017035 Uncharacterised conserved protein UCP035009, HsdR, All3000-type UA74_RS14480 128636ce11016ae68f4c2a48feb166db 390 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 39 121 2.2E-9 T 09-03-2017 IPR029464 Type I restriction enzyme R protein, N-terminal domain UA74_RS04755 98b494b2192f1f87520f500c81e27001 76 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 3.8E-30 T 09-03-2017 IPR021456 Protein of unknown function DUF3107 UA74_RS11030 70a865895205fae48171c0a3c5f82563 106 Gene3D G3DSA:1.10.10.60 3 52 5.1E-7 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS11030 70a865895205fae48171c0a3c5f82563 106 SUPERFAMILY SSF46689 7 55 5.81E-5 T 09-03-2017 IPR009057 Homeodomain-like GO:0003677 UA74_RS27780 ea910c380e2a0c587916bcc5ba2ba9b0 96 Pfam PF11222 Protein of unknown function (DUF3017) 16 89 6.2E-20 T 09-03-2017 IPR021385 Protein of unknown function DUF3017 UA74_RS09385 191f4509fe7afd368911b708faddbd65 67 Pfam PF04149 Domain of unknown function (DUF397) 11 62 5.2E-15 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS05045 0b5f0e88bb66c54dd03f965172e18a82 28 Pfam PF13011 leucine-zipper of insertion element IS481 1 28 5.1E-8 T 09-03-2017 IPR024967 DNA-binding domain, IS481-type UA74_RS18080 615fea1fb9369e511ed4a1dce4c2ec42 223 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 37 219 4.0E-33 T 09-03-2017 IPR004302 Chitin-binding protein, N-terminal UA74_RS18080 615fea1fb9369e511ed4a1dce4c2ec42 223 Gene3D G3DSA:2.70.50.50 37 222 2.3E-41 T 09-03-2017 UA74_RS18080 615fea1fb9369e511ed4a1dce4c2ec42 223 SUPERFAMILY SSF81296 37 222 5.6E-33 T 09-03-2017 IPR014756 Immunoglobulin E-set UA74_RS12025 50d0bf2eb43bf57dcc6aec70ec36d4f0 401 Pfam PF13556 PucR C-terminal helix-turn-helix domain 334 392 1.3E-16 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain UA74_RS16280 b5f3714173809c7022927193be23b0c7 244 Gene3D G3DSA:1.10.10.10 186 229 6.6E-4 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS09865 cee9b703239a8d0b9f087aad111f6d9b 280 Pfam PF14062 Domain of unknown function (DUF4253) 172 280 6.7E-40 T 09-03-2017 IPR025349 Domain of unknown function DUF4253 UA74_RS21840 9c6e2db9528940f0b4672c75fe5487dc 217 Gene3D G3DSA:3.30.1310.10 29 112 1.4E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS21840 9c6e2db9528940f0b4672c75fe5487dc 217 Pfam PF02575 YbaB/EbfC DNA-binding family 34 113 3.1E-10 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS21840 9c6e2db9528940f0b4672c75fe5487dc 217 SUPERFAMILY SSF82607 28 113 2.09E-7 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS23660 3551e0da460c9d17a3a53dfe0e23801e 113 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 2.0E-22 T 09-03-2017 IPR024412 Lsr2 UA74_RS23660 3551e0da460c9d17a3a53dfe0e23801e 113 Pfam PF11774 Lsr2 2 111 4.1E-40 T 09-03-2017 IPR024412 Lsr2 UA74_RS11470 3ed9cfcf029df85fa073b2ddd1f7021f 158 Pfam PF02577 Bifunctional nuclease 7 128 8.1E-45 T 09-03-2017 IPR003729 Bifunctional nuclease domain GO:0004518 UA74_RS11470 3ed9cfcf029df85fa073b2ddd1f7021f 158 SUPERFAMILY SSF103256 3 137 1.44E-46 T 09-03-2017 IPR003729 Bifunctional nuclease domain GO:0004518 UA74_RS30110 3dc4efcc03dec1a63af3e29bef41ec08 700 SUPERFAMILY SSF63829 344 389 8.83E-6 T 09-03-2017 UA74_RS30110 3dc4efcc03dec1a63af3e29bef41ec08 700 SUPERFAMILY SSF63829 423 611 8.83E-6 T 09-03-2017 UA74_RS30110 3dc4efcc03dec1a63af3e29bef41ec08 700 Pfam PF05787 Bacterial protein of unknown function (DUF839) 106 656 1.5E-171 T 09-03-2017 IPR008557 Protein of unknown function DUF839 UA74_RS12470 39de96c2dcb598504436a4e93ec0ab25 135 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 125 4.6E-35 T 09-03-2017 IPR018727 Protein of unknown function DUF2267 UA74_RS27465 7c3fc1c555271ff6042c4ba0ebd428ce 338 SUPERFAMILY SSF48452 99 183 1.63E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS27465 7c3fc1c555271ff6042c4ba0ebd428ce 338 SUPERFAMILY SSF48452 232 296 1.63E-5 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS27465 7c3fc1c555271ff6042c4ba0ebd428ce 338 Gene3D G3DSA:1.25.40.10 100 297 7.3E-8 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS23690 29d12633e7873715b0f0814a51831a04 271 Pfam PF06966 Protein of unknown function (DUF1295) 27 256 4.3E-66 T 09-03-2017 IPR010721 Protein of unknown function DUF1295 UA74_RS08895 c36f367f94beb0df2cf95b455f4ebccc 717 Pfam PF03235 Protein of unknown function DUF262 14 232 9.8E-28 T 09-03-2017 IPR004919 Domain of unknown function DUF262 UA74_RS29580 cc85787a5956c3fec420e48975b41f94 62 Pfam PF04149 Domain of unknown function (DUF397) 7 58 8.8E-16 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS04375 4df64846e586bfaeea5b700c1dd1e1fd 381 SUPERFAMILY SSF89392 101 265 1.92E-8 T 09-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX UA74_RS04375 4df64846e586bfaeea5b700c1dd1e1fd 381 Gene3D G3DSA:2.50.20.10 100 262 1.4E-12 T 09-03-2017 UA74_RS10360 8c6e48e252a64b983c603bb252a0458e 103 Gene3D G3DSA:1.10.10.10 2 97 2.8E-29 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10360 8c6e48e252a64b983c603bb252a0458e 103 SUPERFAMILY SSF46785 2 96 4.12E-23 T 09-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain UA74_RS10360 8c6e48e252a64b983c603bb252a0458e 103 Pfam PF01638 HxlR-like helix-turn-helix 2 87 2.4E-21 T 09-03-2017 IPR002577 Helix-turn-helix, HxlR type UA74_RS10200 3ff52fc1708140279e0a8ad7dc7f1188 218 Pfam PF01810 LysE type translocator 5 215 4.9E-30 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 UA74_RS10200 3ff52fc1708140279e0a8ad7dc7f1188 218 PIRSF PIRSF006324 1 217 8.8E-46 T 09-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 UA74_RS20905 cf66b5836fa96233e77f0307381b72e8 241 Pfam PF14065 Protein of unknown function (DUF4255) 4 179 3.9E-43 T 09-03-2017 IPR025351 Protein of unknown function DUF4255 UA74_RS12565 6a1a6e09013db153540bc67151f4168a 544 Pfam PF05960 Bacterial protein of unknown function (DUF885) 25 538 1.5E-106 T 09-03-2017 IPR010281 Protein of unknown function DUF885 UA74_RS08585 f6dfba8316990d6f0a694fa0a1cfc237 669 Pfam PF13520 Amino acid permease 57 458 1.7E-24 T 09-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 UA74_RS12745 7c98888dd8a6691b361a54a80ff61c16 220 Pfam PF06439 Domain of Unknown Function (DUF1080) 43 214 1.3E-42 T 09-03-2017 IPR010496 Domain of unknown function DUF1080 UA74_RS30240 9e44f1b4de49d169889001e0f3419b91 407 Gene3D G3DSA:1.20.1250.20 3 175 6.2E-25 T 09-03-2017 UA74_RS30240 9e44f1b4de49d169889001e0f3419b91 407 Gene3D G3DSA:1.20.1250.20 197 374 5.8E-14 T 09-03-2017 UA74_RS30240 9e44f1b4de49d169889001e0f3419b91 407 SUPERFAMILY SSF103473 3 379 5.1E-51 T 09-03-2017 IPR020846 Major facilitator superfamily domain UA74_RS30240 9e44f1b4de49d169889001e0f3419b91 407 Pfam PF07690 Major Facilitator Superfamily 8 312 3.7E-35 T 09-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_RS29300 65b27d5be93846290605af099b98d99c 265 Pfam PF11209 Protein of unknown function (DUF2993) 17 253 8.5E-42 T 09-03-2017 IPR021373 Protein of unknown function DUF2993 UA74_RS13890 cf1f5ba3e10eb15092590e4182c8883b 584 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 16 570 5.6E-82 T 09-03-2017 IPR010144 CRISPR-associated protein, Csd1-type UA74_RS13890 cf1f5ba3e10eb15092590e4182c8883b 584 TIGRFAM TIGR01863 cas_Csd1: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG 3 572 7.7E-71 T 09-03-2017 IPR010144 CRISPR-associated protein, Csd1-type UA74_RS11205 e5101d95976c7a50611cf8c53be7fa06 371 Pfam PF01757 Acyltransferase family 2 342 8.6E-16 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS18245 fa5da9ffee8fdccf93a415f1b7726217 171 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 75 167 3.0E-32 T 09-03-2017 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 UA74_RS20840 dc284d12ec3a35312d2b2bc0a7af385c 141 Pfam PF06841 T4-like virus tail tube protein gp19 9 138 1.5E-30 T 09-03-2017 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 UA74_RS20840 dc284d12ec3a35312d2b2bc0a7af385c 141 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 139 1.6E-25 T 09-03-2017 IPR011747 Conserved hypothetical protein CHP02241 UA74_RS23105 3548b8c97e40d90becc75fd52c5f8d03 64 Pfam PF04149 Domain of unknown function (DUF397) 11 62 1.9E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS20635 19e98c7fad357c15c396371ae4f4f043 630 Pfam PF09369 Domain of unknown function (DUF1998) 494 596 7.3E-9 T 09-03-2017 IPR018973 DEAD/DEAH-box helicase, putative UA74_RS11560 2778438844d65564e9472fb084bdbe21 454 SUPERFAMILY SSF81995 5 50 8.37E-5 T 09-03-2017 UA74_RS26680 02bb045b0cd6ab2cdffb9705705d7295 272 SUPERFAMILY SSF89392 92 257 8.63E-9 T 09-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX UA74_RS18680 3267ecb6fe68da1f51c1a5fcc0d232ce 348 Pfam PF08012 Protein of unknown function (DUF1702) 5 336 3.7E-124 T 09-03-2017 IPR012964 Protein of unknown function DUF1702 UA74_RS03750 b0ceff6e441d050437157875ea54b58f 179 Pfam PF04417 Protein of unknown function (DUF501) 35 156 3.3E-36 T 09-03-2017 IPR007511 Protein of unknown function DUF501 UA74_RS19780 105c412b5a76564b01950b70cb05c51c 158 SUPERFAMILY SSF55961 10 154 1.9E-35 T 09-03-2017 UA74_RS19780 105c412b5a76564b01950b70cb05c51c 158 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 152 5.6E-18 T 09-03-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 UA74_RS19780 105c412b5a76564b01950b70cb05c51c 158 Gene3D G3DSA:3.30.530.20 7 155 1.1E-31 T 09-03-2017 IPR023393 START-like domain UA74_RS09195 7a42deb536d4eeb120b5cd521bae0a81 146 PIRSF PIRSF017371 1 146 1.8E-52 T 09-03-2017 IPR014488 Uncharacterised conserved protein UCP017371 UA74_RS09195 7a42deb536d4eeb120b5cd521bae0a81 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 145 1.9E-15 T 09-03-2017 IPR019587 Polyketide cyclase/dehydrase UA74_RS09195 7a42deb536d4eeb120b5cd521bae0a81 146 SUPERFAMILY SSF55961 5 144 2.17E-9 T 09-03-2017 UA74_RS06915 1aa6684c4d564684af82f0063a88286a 73 Pfam PF12277 Protein of unknown function (DUF3618) 2 47 4.4E-17 T 09-03-2017 IPR022062 Protein of unknown function DUF3618 UA74_RS00310 8118dd121f27b33ab1c8ba3ffbc4bff2 407 Gene3D G3DSA:3.40.50.300 291 341 3.1E-4 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS27080 bfc1589ca77e61a7d923fd245ec8cd46 74 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 12 69 3.3E-20 T 09-03-2017 IPR032716 Acyl-CoA carboxylase epsilon subunit UA74_RS26435 fa36ec9ca631a31ac922a3f87f86a9ea 538 Pfam PF13556 PucR C-terminal helix-turn-helix domain 466 521 3.7E-17 T 09-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain UA74_RS26675 6875dfe9aa279051e4f6dfe487a3652e 291 SUPERFAMILY SSF89392 56 278 1.1E-9 T 09-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX UA74_RS06775 908a9b54726845351959c386c0d48c50 163 Pfam PF03703 Bacterial PH domain 73 144 3.3E-14 T 09-03-2017 IPR005182 Domain of unknown function DUF304 UA74_RS16380 4fa7c445db0d2b60b0b2b90e1e3090ac 237 Pfam PF07508 Recombinase 27 136 3.6E-16 T 09-03-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 UA74_RS29445 49dc74fbff4170578e8af3185e60fd1f 541 SUPERFAMILY SSF140459 25 171 5.75E-5 T 09-03-2017 UA74_RS24265 c565417abad9e9fbd8488d6c45e0ce08 173 Pfam PF07940 Heparinase II/III-like protein 1 157 2.7E-8 T 09-03-2017 IPR012480 Heparinase II/III-like GO:0016829 UA74_RS20580 0a02b0076e69c88f7a32f98ac12dba0f 258 PIRSF PIRSF015736 5 251 4.2E-69 T 09-03-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_RS10840 fdbf9962a61deee07898600600e97366 451 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 22 304 3.2E-68 T 09-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 UA74_RS29820 a03fa698257013519c3fdc5bd15d4db7 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.7E-16 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS01115 cf5698245c16e09ab290538d55119b1a 628 Pfam PF00326 Prolyl oligopeptidase family 415 622 1.5E-44 T 09-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_RS01115 cf5698245c16e09ab290538d55119b1a 628 Gene3D G3DSA:2.120.10.30 39 101 1.4E-23 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS01115 cf5698245c16e09ab290538d55119b1a 628 Gene3D G3DSA:2.120.10.30 151 330 1.4E-23 T 09-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like UA74_RS01115 cf5698245c16e09ab290538d55119b1a 628 SUPERFAMILY SSF53474 379 621 2.26E-56 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01115 cf5698245c16e09ab290538d55119b1a 628 Gene3D G3DSA:3.40.50.1820 379 616 1.8E-58 T 09-03-2017 IPR029058 Alpha/Beta hydrolase fold UA74_RS01115 cf5698245c16e09ab290538d55119b1a 628 SUPERFAMILY SSF82171 145 360 7.46E-19 T 09-03-2017 UA74_RS01115 cf5698245c16e09ab290538d55119b1a 628 SUPERFAMILY SSF82171 31 117 7.46E-19 T 09-03-2017 UA74_RS00545 a5251f1f824bb395aecfeb3d1897c1d5 335 PIRSF PIRSF000267 1 332 7.6E-106 T 09-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_RS00545 a5251f1f824bb395aecfeb3d1897c1d5 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 1.1E-97 T 09-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_RS00545 a5251f1f824bb395aecfeb3d1897c1d5 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 206 3.6E-63 T 09-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_RS00180 2f7db8f9ea127249cc3dd11a2cff5aa1 1074 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 726 839 3.1E-17 T 09-03-2017 IPR007817 Pyoverdine biosynthesis UA74_RS02410 8f78254e82944b96f4afd236ff9afe9e 96 Pfam PF14012 Protein of unknown function (DUF4229) 16 77 3.2E-12 T 09-03-2017 IPR025323 Protein of unknown function DUF4229 UA74_RS26210 694a7f30ae4fbb4ca1d187d9f2147993 282 Pfam PF13460 NAD(P)H-binding 6 181 3.0E-14 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26210 694a7f30ae4fbb4ca1d187d9f2147993 282 Gene3D G3DSA:3.40.50.720 2 216 3.3E-31 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS26210 694a7f30ae4fbb4ca1d187d9f2147993 282 SUPERFAMILY SSF51735 2 261 1.5E-43 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21135 a8295c1d697bb3751e8f00c26a572de8 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 282 2.2E-17 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21135 a8295c1d697bb3751e8f00c26a572de8 292 SUPERFAMILY SSF161098 27 292 4.11E-61 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS21135 a8295c1d697bb3751e8f00c26a572de8 292 Gene3D G3DSA:1.10.3720.10 27 277 1.3E-53 T 09-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 UA74_RS18150 dd6856168440055f008ef1966ed9bebd 430 Pfam PF00881 Nitroreductase family 210 395 8.1E-13 T 09-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_RS18150 dd6856168440055f008ef1966ed9bebd 430 SUPERFAMILY SSF55469 297 397 2.54E-16 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS18150 dd6856168440055f008ef1966ed9bebd 430 SUPERFAMILY SSF55469 203 269 2.54E-16 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS18150 dd6856168440055f008ef1966ed9bebd 430 Gene3D G3DSA:3.40.109.10 201 396 1.1E-15 T 09-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_RS18150 dd6856168440055f008ef1966ed9bebd 430 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 225 394 4.1E-32 T 09-03-2017 IPR020051 SagB-type dehydrogenase domain UA74_RS29645 733d0f392f53e1763988bfa6a246c6f3 301 Pfam PF06197 Protein of unknown function (DUF998) 10 203 3.4E-16 T 09-03-2017 IPR009339 Protein of unknown function DUF998 UA74_RS05995 5ee7d393ea0b87dfd19f3974a9d723ed 60 Gene3D G3DSA:3.40.1490.10 3 60 1.4E-6 T 09-03-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 UA74_RS14025 797239d1f14e29a0afd2a1f49305117e 226 Pfam PF13250 Domain of unknown function (DUF4041) 137 191 1.1E-5 T 09-03-2017 IPR025280 Domain of unknown function DUF4041 UA74_RS27300 ed873753d1eed1b4cc7f99f5cc68d79f 359 Pfam PF02653 Branched-chain amino acid transport system / permease component 81 346 8.7E-46 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS07670 0f7c7c90cd79848dfb21a462b3f8bf46 108 Pfam PF02426 Muconolactone delta-isomerase 1 89 1.4E-15 T 09-03-2017 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 UA74_RS07670 0f7c7c90cd79848dfb21a462b3f8bf46 108 SUPERFAMILY SSF54909 1 95 5.36E-21 T 09-03-2017 IPR011008 Dimeric alpha-beta barrel UA74_RS01260 2b36870a9c475202cae0bb78459d6e4f 188 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 41 155 8.4E-28 T 09-03-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III UA74_RS19030 acd309d048830ec6fc7270ab66867e63 172 Pfam PF14015 Protein of unknown function (DUF4231) 38 123 5.6E-8 T 09-03-2017 IPR025325 Protein of unknown function DUF4231 UA74_RS17775 a291095e9319ce0c3977278a674a8ba0 221 Pfam PF08044 Domain of unknown function (DUF1707) 8 60 2.1E-16 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS08560 48ffcee7291449aa0d28f6f2565fbd47 231 Pfam PF12502 Protein of unknown function (DUF3710) 30 195 2.8E-60 T 09-03-2017 IPR022183 Protein of unknown function DUF3710 UA74_RS24860 78eb41733ae09a2fcb8d91d443a7e5d2 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 3.6E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS05685 c6c3c3c68026f33ec465cdf11f7c4279 413 Gene3D G3DSA:3.30.1540.10 238 319 1.4E-31 T 09-03-2017 UA74_RS05685 c6c3c3c68026f33ec465cdf11f7c4279 413 Pfam PF02515 CoA-transferase family III 17 390 1.8E-129 T 09-03-2017 IPR003673 CoA-transferase family III GO:0003824 UA74_RS05685 c6c3c3c68026f33ec465cdf11f7c4279 413 SUPERFAMILY SSF89796 14 413 4.19E-134 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS05685 c6c3c3c68026f33ec465cdf11f7c4279 413 Gene3D G3DSA:3.40.50.10540 320 413 6.9E-113 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS05685 c6c3c3c68026f33ec465cdf11f7c4279 413 Gene3D G3DSA:3.40.50.10540 14 231 6.9E-113 T 09-03-2017 IPR023606 CoA-transferase family III domain UA74_RS27545 b83aeaab5def9295312111c32a2e3e87 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 4.1E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS24295 dbd925f7f489ea82dc4720b29e7cd55d 680 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 16 363 3.8E-103 T 09-03-2017 IPR016624 Uncharacterised conserved protein UCP014753 UA74_RS25115 13f2b60963f072110d4a824280af5b27 208 Pfam PF12079 Protein of unknown function (DUF3558) 17 199 2.9E-22 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS00375 3f0e8b05856c0c2014950671ed6cdda1 294 Pfam PF14219 Domain of unknown function (DUF4328) 101 257 1.4E-35 T 09-03-2017 IPR025565 Domain of unknown function DUF4328 UA74_RS25095 c6610d0f861c58466093075029b36023 63 Pfam PF04149 Domain of unknown function (DUF397) 9 62 7.6E-23 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS28470 ad45293fcf6a93ed2fc5bff8b2637a82 206 Pfam PF10801 Protein of unknown function (DUF2537) 120 199 2.7E-22 T 09-03-2017 IPR024244 Protein of unknown function DUF2537 UA74_RS29615 1bcdf236441490f9d46dbe9f399aba65 214 Pfam PF07510 Protein of unknown function (DUF1524) 110 208 2.6E-12 T 09-03-2017 IPR011089 Domain of unknown function DUF1524 UA74_RS06205 c01fabe08f31e53b08cb458e77104696 395 Pfam PF13449 Esterase-like activity of phytase 50 381 4.6E-67 T 09-03-2017 IPR027372 Phytase-like domain UA74_RS18310 9d494b7899396672dc6bc2916c6f67a4 62 Pfam PF13699 Domain of unknown function (DUF4157) 1 61 8.6E-23 T 09-03-2017 IPR025295 Domain of unknown function DUF4157 UA74_RS06295 e0b455f07853cffad7c9b474fdcaef23 187 Pfam PF09438 Domain of unknown function (DUF2017) 6 184 1.0E-59 T 09-03-2017 IPR018561 Domain of unknown function DUF2017 UA74_RS09810 9cd03a3a74dd44769443877e43ad1559 212 SUPERFAMILY SSF53254 5 174 4.71E-32 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS09810 9cd03a3a74dd44769443877e43ad1559 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 156 1.0E-28 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS09810 9cd03a3a74dd44769443877e43ad1559 212 SMART SM00855 4 149 9.8E-7 T 09-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_RS09810 9cd03a3a74dd44769443877e43ad1559 212 Gene3D G3DSA:3.40.50.1240 4 173 7.1E-33 T 09-03-2017 IPR029033 Histidine phosphatase superfamily UA74_RS19130 57bb991671632f32e3ec8a0ba69139ee 104 Pfam PF03235 Protein of unknown function DUF262 8 68 1.2E-11 T 09-03-2017 IPR004919 Domain of unknown function DUF262 UA74_RS22890 fa925a38d09e2e33ec47fee18f40cb90 81 Pfam PF04149 Domain of unknown function (DUF397) 18 73 3.6E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS16510 3164bf4a1eb6adab4d3e3126d5fb0766 270 Pfam PF14765 Polyketide synthase dehydratase 6 267 2.5E-57 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS16510 3164bf4a1eb6adab4d3e3126d5fb0766 270 SMART SM00826 1 164 6.9E-77 T 09-03-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_RS02045 cfad92829392237ce0b47f72449237a0 281 Gene3D G3DSA:1.10.260.40 4 70 7.9E-10 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02045 cfad92829392237ce0b47f72449237a0 281 SMART SM00530 16 71 3.3E-6 T 09-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_RS02045 cfad92829392237ce0b47f72449237a0 281 SUPERFAMILY SSF47413 11 70 2.22E-8 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS02045 cfad92829392237ce0b47f72449237a0 281 Pfam PF13560 Helix-turn-helix domain 13 73 9.1E-12 T 09-03-2017 UA74_RS23345 5a502ed8c0c95d9c9ba45f385a6b936d 67 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 8 57 3.8E-7 T 09-03-2017 IPR025161 Putative transposase IS4/IS5 family UA74_RS24780 fba0e36ed2d3386b40831dab630eafc0 567 Pfam PF05960 Bacterial protein of unknown function (DUF885) 27 564 1.5E-157 T 09-03-2017 IPR010281 Protein of unknown function DUF885 UA74_RS10245 1d5509c0f1cf48407027c986229d8fc1 481 Pfam PF01757 Acyltransferase family 58 432 7.5E-14 T 09-03-2017 IPR002656 Acyltransferase 3 GO:0016747 UA74_RS09380 efdd32491d812b6047f6d5a55ab259f9 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 1.1E-17 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS15215 39295dc9dc3f078c4988f1108eb67352 93 Pfam PF01391 Collagen triple helix repeat (20 copies) 29 83 7.5E-8 T 09-03-2017 IPR008160 Collagen triple helix repeat UA74_RS15215 39295dc9dc3f078c4988f1108eb67352 93 Pfam PF01391 Collagen triple helix repeat (20 copies) 11 65 1.5E-8 T 09-03-2017 IPR008160 Collagen triple helix repeat UA74_RS10295 0fcf4cdb00a58c5e572171cc895ad212 347 Pfam PF01794 Ferric reductase like transmembrane component 75 211 1.2E-11 T 09-03-2017 IPR013130 Ferric reductase transmembrane component-like domain UA74_RS21240 f6df8105a299e326e8e17322001df7a3 234 Pfam PF13398 Peptidase M50B-like 24 224 2.2E-57 T 09-03-2017 UA74_RS21835 ced3bd1e9210e34c6ec40c57eabb2fc7 264 Pfam PF14011 EspG family 9 250 5.4E-59 T 09-03-2017 IPR025734 EspG family UA74_RS29630 7ce22de00337cad786f37447b3e0e198 206 SUPERFAMILY SSF55961 8 142 2.36E-15 T 09-03-2017 UA74_RS29630 7ce22de00337cad786f37447b3e0e198 206 Gene3D G3DSA:3.30.530.20 7 121 4.4E-7 T 09-03-2017 IPR023393 START-like domain UA74_RS16170 02271d9f17a3b169f2a073fce6c350cd 214 Pfam PF01478 Type IV leader peptidase family 71 184 3.8E-12 T 09-03-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 UA74_RS04150 be52273f370ecdb3584c971a0a9f530c 203 Pfam PF14030 Protein of unknown function (DUF4245) 19 194 4.8E-41 T 09-03-2017 IPR025339 Protein of unknown function DUF4245 UA74_RS29385 8fa3c0d0d5359640a64162f5188851f6 259 Pfam PF14011 EspG family 10 249 6.6E-49 T 09-03-2017 IPR025734 EspG family UA74_RS03825 f220dd39d8e5c7d2ed2031a344b1e0c0 555 Pfam PF09594 Protein of unknown function (DUF2029) 85 318 9.6E-52 T 09-03-2017 IPR018584 Glycosyltransferase family 87 GO:0016758 UA74_RS03925 310d511f1bd3476ed67d87c0e9bd83bb 63 Pfam PF04149 Domain of unknown function (DUF397) 8 60 3.1E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS15525 4abdb37de82bf810471f3ecc7122b631 250 SUPERFAMILY SSF53335 19 226 4.42E-37 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15525 4abdb37de82bf810471f3ecc7122b631 250 Gene3D G3DSA:3.40.50.150 18 218 3.2E-35 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS15525 4abdb37de82bf810471f3ecc7122b631 250 Pfam PF08241 Methyltransferase domain 59 151 9.7E-21 T 09-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 UA74_RS23750 703fce8476f54cb165c487050144b6ee 168 Pfam PF03780 Asp23 family, cell envelope-related function 105 159 8.8E-7 T 09-03-2017 IPR005531 Alkaline shock protein Asp23 UA74_RS00700 2c1463f1a8fca9abf5a60438d010c2c0 195 Pfam PF10759 Protein of unknown function (DUF2587) 47 182 9.4E-77 T 09-03-2017 IPR019695 Bacterial proteasome activator GO:0061136 UA74_RS23335 36b55e2572cc7b5c4fe3ce19d74cb194 109 SUPERFAMILY SSF56059 33 105 2.44E-6 T 09-03-2017 UA74_RS27395 41614781eba1303676f32f95d7362e6e 143 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 109 2.3E-25 T 09-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 UA74_RS21530 501d827160ab0296272b323c658e0469 282 Gene3D G3DSA:3.40.50.720 1 209 7.0E-37 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21530 501d827160ab0296272b323c658e0469 282 SUPERFAMILY SSF51735 1 229 9.19E-49 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS21530 501d827160ab0296272b323c658e0469 282 Pfam PF13460 NAD(P)H-binding 3 174 3.7E-24 T 09-03-2017 IPR016040 NAD(P)-binding domain UA74_RS10885 2f2206384d323855379a1abeeee904d7 284 Pfam PF03591 AzlC protein 2 137 2.5E-33 T 09-03-2017 IPR011606 Branched-chain amino acid transport, permease UA74_RS13400 cbee79d24d7f7b10a438fbc88fbaefc5 413 Pfam PF01699 Sodium/calcium exchanger protein 34 182 2.3E-12 T 09-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 UA74_RS13400 cbee79d24d7f7b10a438fbc88fbaefc5 413 Pfam PF01699 Sodium/calcium exchanger protein 214 357 1.1E-10 T 09-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 UA74_RS20165 0bfb721ef01a8815946fd19e92351348 91 SUPERFAMILY SSF82607 19 90 4.19E-5 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS20165 0bfb721ef01a8815946fd19e92351348 91 Gene3D G3DSA:3.30.1310.10 37 89 1.8E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS20165 0bfb721ef01a8815946fd19e92351348 91 Pfam PF02575 YbaB/EbfC DNA-binding family 25 90 4.6E-6 T 09-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_RS03720 5130018b54f3f9a348369b14d7e98fc9 243 Gene3D G3DSA:1.10.530.10 155 217 2.0E-10 T 09-03-2017 UA74_RS03720 5130018b54f3f9a348369b14d7e98fc9 243 Gene3D G3DSA:1.10.530.10 81 115 2.0E-10 T 09-03-2017 UA74_RS03720 5130018b54f3f9a348369b14d7e98fc9 243 SUPERFAMILY SSF53955 66 232 1.2E-35 T 09-03-2017 IPR023346 Lysozyme-like domain UA74_RS03720 5130018b54f3f9a348369b14d7e98fc9 243 Pfam PF13406 Transglycosylase SLT domain 155 199 6.4E-8 T 09-03-2017 IPR031304 Transglycosylase SLT domain 2 UA74_RS23920 da93d474b188a8aede57e94ce6113674 657 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 17 363 1.2E-105 T 09-03-2017 IPR016624 Uncharacterised conserved protein UCP014753 UA74_RS02205 7eeea4fc396d0900cc9645294884d45a 161 Pfam PF10722 Putative bacterial sensory transduction regulator 3 123 5.4E-19 T 09-03-2017 IPR019660 Putative sensory transduction regulator YbjN UA74_RS02205 7eeea4fc396d0900cc9645294884d45a 161 SUPERFAMILY SSF69635 1 126 8.48E-29 T 09-03-2017 UA74_RS02205 7eeea4fc396d0900cc9645294884d45a 161 Gene3D G3DSA:3.30.1460.10 1 134 7.6E-17 T 09-03-2017 UA74_RS10685 8a12609d2e90632a1418d706e9266e74 381 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 334 1.3E-47 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 UA74_RS00465 08bc0ab949a197b5de53ed353079bba6 205 Pfam PF12079 Protein of unknown function (DUF3558) 21 202 2.5E-22 T 09-03-2017 IPR024520 Protein of unknown function DUF3558 UA74_RS05100 891721b36ffd513d624732771b898547 51 Gene3D G3DSA:1.10.260.40 2 49 4.9E-12 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05100 891721b36ffd513d624732771b898547 51 SUPERFAMILY SSF47413 2 49 4.56E-11 T 09-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 UA74_RS05100 891721b36ffd513d624732771b898547 51 Pfam PF13560 Helix-turn-helix domain 3 50 1.4E-8 T 09-03-2017 UA74_RS11830 da44fb7b08631e8411625173c3a7548d 199 SUPERFAMILY SSF81301 17 151 7.93E-28 T 09-03-2017 UA74_RS11830 da44fb7b08631e8411625173c3a7548d 199 Pfam PF14907 Uncharacterised nucleotidyltransferase 17 181 1.3E-8 T 09-03-2017 UA74_RS09100 a6f1fd49e1e6b8011675ba818c8f8f95 92 Pfam PF04226 Transglycosylase associated protein 33 82 1.6E-13 T 09-03-2017 IPR007341 Transglycosylase-associated protein GO:0016021 UA74_RS06020 f67933faa8cd965e470aaac3d19361a8 49 Pfam PF16483 Beta-1,3-glucanase 3 46 3.5E-15 T 09-03-2017 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 UA74_RS28940 16db38d838fa74a33e616daf4551b6d0 288 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 49 216 2.3E-54 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 UA74_RS28940 16db38d838fa74a33e616daf4551b6d0 288 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 45 220 1.5E-36 T 09-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 UA74_RS04530 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 189 201 7.9E-9 T 09-03-2017 UA74_RS04530 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 227 239 7.9E-9 T 09-03-2017 UA74_RS04530 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 262 278 7.9E-9 T 09-03-2017 UA74_RS04530 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 288 305 7.9E-9 T 09-03-2017 UA74_RS04530 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 239 260 7.9E-9 T 09-03-2017 UA74_RS30155 407d9d371dab0913c1ce4945d12a4b25 460 PIRSF PIRSF010361 4 458 1.2E-74 T 09-03-2017 IPR016570 Uncharacterised conserved protein UCP010361, membrane UA74_RS30155 407d9d371dab0913c1ce4945d12a4b25 460 Pfam PF05007 Mannosyltransferase (PIG-M) 186 376 4.1E-6 T 09-03-2017 IPR007704 Mannosyltransferase, DXD GO:0006506|GO:0016021|GO:0016758 Reactome: R-HSA-162710 UA74_RS22925 08ff72fc30d09d8584f12b3bc01fecfa 273 Pfam PF03756 A-factor biosynthesis hotdog domain 102 234 8.9E-21 T 09-03-2017 IPR005509 A-factor biosynthesis hotdog domain UA74_RS15915 13f3d45efcf7cb1af8bab1ce6876e12e 340 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 13 308 1.7E-50 T 09-03-2017 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap UA74_RS15915 13f3d45efcf7cb1af8bab1ce6876e12e 340 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 8 243 7.5E-24 T 09-03-2017 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR UA74_RS26120 5534f63165c5452a418991e2b48ad82b 76 Pfam PF04149 Domain of unknown function (DUF397) 17 68 3.6E-12 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS00040 19f846034562138e5d167e61a88ee13d 219 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 103 217 1.0E-44 T 09-03-2017 IPR021949 Domain of unknown function DUF3566. transmembrane UA74_RS09165 bec50925cdf3908735d9b3db48f91ec5 412 Pfam PF04892 VanZ like family 48 188 8.2E-18 T 09-03-2017 IPR006976 VanZ-like UA74_RS09530 565e309b6833c6c20ab1a77b0f2cbaec 74 TIGRFAM TIGR03898 lanti_MRSA_kill: type 2 lantibiotic, mersacidin/lichenicidin family 2 35 3.8E-9 T 09-03-2017 IPR027635 Type 2 lantibiotic, leader peptide domain GO:0042742 UA74_RS00215 d0637741c899bb31fdad4d34d1bac8ec 338 Pfam PF05425 Copper resistance protein D 237 335 8.5E-19 T 09-03-2017 IPR008457 Copper resistance protein D GO:0016021 UA74_RS05740 7f73681ccc52725bb6038883b715f043 363 SUPERFAMILY SSF140453 23 96 4.45E-5 T 09-03-2017 IPR010310 Type VII secretion system ESAT-6-like UA74_RS09500 db13c5d7c851dfac586b839091b0c65f 154 Pfam PF09335 SNARE associated Golgi protein 28 144 5.0E-8 T 09-03-2017 IPR032816 SNARE associated Golgi protein UA74_RS00135 65c486422df058515158722dd50de7dd 481 Pfam PF01098 Cell cycle protein 89 453 5.8E-85 T 09-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 UA74_RS03250 1478adf7e3174e42920c4ff0d4f285f8 219 SMART SM00858 58 120 4.4E-7 T 09-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_RS03185 a1e85b94834e53ce6e036e80aaf36034 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 3.7E-32 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS03185 a1e85b94834e53ce6e036e80aaf36034 146 Pfam PF04075 Domain of unknown function (DUF385) 15 143 4.1E-50 T 09-03-2017 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_RS27050 f8eb58db1f0937ea30741aa67cf1b7d9 231 Pfam PF01955 Adenosylcobinamide amidohydrolase 20 199 2.8E-48 T 09-03-2017 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ UA74_RS05530 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 335 347 4.0E-15 T 09-03-2017 UA74_RS05530 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 434 459 4.0E-15 T 09-03-2017 UA74_RS05530 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 366 387 4.0E-15 T 09-03-2017 UA74_RS05530 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 477 489 4.0E-15 T 09-03-2017 UA74_RS05530 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 387 403 4.0E-15 T 09-03-2017 UA74_RS05530 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 416 433 4.0E-15 T 09-03-2017 UA74_RS10300 e26c86da5cd5a2eb3d09f819a18dc032 543 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 25 533 3.2E-96 T 09-03-2017 IPR026487 Sporadically distributed protein CHP04141 UA74_RS29125 bfbbe5b81a208eada2744952df742291 199 Pfam PF06197 Protein of unknown function (DUF998) 9 194 9.3E-38 T 09-03-2017 IPR009339 Protein of unknown function DUF998 UA74_RS02060 34a971accde28df56d24cf1dd06a81e8 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 7.0E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS13285 49f22701db2e9267fce6c1f0c2eaeff6 618 Gene3D G3DSA:3.40.50.300 294 474 1.2E-7 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13285 49f22701db2e9267fce6c1f0c2eaeff6 618 SUPERFAMILY SSF52540 284 472 2.7E-8 T 09-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_RS13285 49f22701db2e9267fce6c1f0c2eaeff6 618 Pfam PF09818 Predicted ATPase of the ABC class 32 482 1.1E-161 T 09-03-2017 IPR019195 ABC transporter, ATPase, putative UA74_RS16425 df04ce25b6d947c81d84f1b3f5e8b5f8 143 Pfam PF13276 HTH-like domain 62 117 2.3E-18 T 09-03-2017 IPR025948 HTH-like domain UA74_RS18005 716875f0f8ae71aa5bae628d805e84f8 92 Pfam PF09851 Short C-terminal domain 60 81 9.3E-7 T 09-03-2017 IPR018649 SHOCT domain UA74_RS18560 4514b1ed44397b51e9ee90bccb3368f6 62 Pfam PF04149 Domain of unknown function (DUF397) 7 57 8.2E-19 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS04845 e34e7cf924e742fa162b45e50fdbb4ea 556 Pfam PF09972 Predicted membrane protein (DUF2207) 27 497 1.3E-44 T 09-03-2017 IPR018702 Protein of unknown function DUF2207, membrane UA74_RS26420 8e44047f2e96de2c11a15fbcd53a6405 110 Pfam PF02656 Domain of unknown function (DUF202) 12 73 5.0E-12 T 09-03-2017 IPR003807 Domain of unknown function DUF202 UA74_RS12185 9776db555a16d23d29236911485a4df5 445 Pfam PF02378 Phosphotransferase system, EIIC 25 336 1.2E-70 T 09-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UA74_RS14490 3286560d6dfabfd99ad4b327788c87ce 72 Pfam PF11160 Protein of unknown function (DUF2945) 9 68 1.2E-24 T 09-03-2017 IPR021331 Protein of unknown function DUF2945 UA74_RS20940 45fff93c9873ea80b67ea976d4a85a9f 62 Pfam PF04149 Domain of unknown function (DUF397) 7 57 2.6E-16 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS00695 1e10ae4b091eed281fe42c51569fdfd8 286 Pfam PF01061 ABC-2 type transporter 38 247 1.3E-24 T 09-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_RS16250 9aa21a21d8ccc3d5828e052144ecfed8 596 SUPERFAMILY SSF53300 427 580 2.78E-9 T 09-03-2017 IPR002035 von Willebrand factor, type A UA74_RS03100 605041461c755ac84047d554f05970a0 145 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 2.2E-19 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS03620 b7c40c7be81cc47c812b49f756a92bb8 36 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 1 35 5.5E-13 T 09-03-2017 IPR019933 DivIVA domain UA74_RS28710 8a379c5914f648ae8eaf6520b3419407 725 Pfam PF12770 CHAT domain 423 708 1.5E-31 T 09-03-2017 IPR024983 CHAT domain UA74_RS20800 74b117d9114815a1375e6f7a2577848c 249 Gene3D G3DSA:2.60.120.260 118 247 9.1E-7 T 09-03-2017 IPR008979 Galactose-binding domain-like UA74_RS06825 4d8c4184571997f7b92f94e824158016 471 Pfam PF08309 LVIVD repeat 70 100 0.021 T 09-03-2017 IPR013211 LVIVD UA74_RS06825 4d8c4184571997f7b92f94e824158016 471 SUPERFAMILY SSF75011 148 437 1.12E-8 T 09-03-2017 UA74_RS16070 7688d9f4f278fc82959d282f67bdd694 108 Gene3D G3DSA:1.10.630.10 5 97 7.3E-14 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS16070 7688d9f4f278fc82959d282f67bdd694 108 SUPERFAMILY SSF48264 5 97 1.11E-9 T 09-03-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_RS09625 e78a6ac639e577b62e641c6cefe3fe9b 272 Pfam PF04012 PspA/IM30 family 3 240 2.5E-50 T 09-03-2017 IPR007157 PspA/IM30 UA74_RS13245 be064ebfcc036c2f278092b260171ec2 304 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 15 263 8.5E-68 T 09-03-2017 IPR014145 DNA ligase D, polymerase domain UA74_RS29310 81e49e9bd74451c1220d38281a960d8f 151 Pfam PF14340 Domain of unknown function (DUF4395) 12 141 8.6E-39 T 09-03-2017 IPR025508 Domain of unknown function DUF4395 UA74_RS21335 a9abc974dbc404f887800943b724e267 290 Pfam PF09335 SNARE associated Golgi protein 46 163 4.8E-20 T 09-03-2017 IPR032816 SNARE associated Golgi protein UA74_RS04565 96d3562eb54d2148e64a78c74e7e4abc 258 Pfam PF14011 EspG family 13 252 5.8E-50 T 09-03-2017 IPR025734 EspG family UA74_RS23210 1a2794df2fc705b2bd4960115e7ce916 382 Pfam PF11991 Tryptophan dimethylallyltransferase 79 264 4.2E-16 T 09-03-2017 IPR017795 Aromatic prenyltransferase, DMATS type GO:0009820|GO:0050364 UA74_RS30125 a9baccc8dd22166bf5ce4e506ebfda50 170 Pfam PF06803 Protein of unknown function (DUF1232) 93 127 1.2E-13 T 09-03-2017 IPR010652 Protein of unknown function DUF1232 UA74_RS27730 8aa2d31c269304220cd2f4262cb0efa4 219 Pfam PF08044 Domain of unknown function (DUF1707) 19 71 7.5E-21 T 09-03-2017 IPR012551 Protein of unknown function DUF1707 UA74_RS25435 503629afdd81b2515323902c14f17773 281 Pfam PF02104 SURF1 family 9 212 1.0E-23 T 09-03-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_RS17825 457b6eee22da0c8c393c58953854da9b 250 Pfam PF13471 Transglutaminase-like superfamily 138 239 2.7E-20 T 09-03-2017 IPR032708 Microcin J25-processing protein McjB, C-terminal UA74_RS09535 91602c2b0d9589905a8174b338d5953a 72 TIGRFAM TIGR03898 lanti_MRSA_kill: type 2 lantibiotic, mersacidin/lichenicidin family 3 45 6.5E-11 T 09-03-2017 IPR027635 Type 2 lantibiotic, leader peptide domain GO:0042742 UA74_RS19265 83cb362910a4571e9ab9ad8e48f334c4 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3 92 5.2E-21 T 09-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 UA74_RS01265 41dcf36152c1b2039a50bcc6c1ce9586 257 Pfam PF01925 Sulfite exporter TauE/SafE 137 248 7.6E-20 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_RS01265 41dcf36152c1b2039a50bcc6c1ce9586 257 Pfam PF01925 Sulfite exporter TauE/SafE 3 115 1.1E-25 T 09-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_RS14200 bf1543ce581284c6c8447e749675998c 87 Gene3D G3DSA:3.20.20.30 7 82 3.0E-5 T 09-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_RS12205 a8e6c3f4d3ab08fab970348a9062d16b 221 Pfam PF01478 Type IV leader peptidase family 84 191 5.6E-8 T 09-03-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 UA74_RS03930 2873746389507f1464f059b4dbba7e4b 66 Pfam PF04149 Domain of unknown function (DUF397) 10 59 1.8E-14 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS28495 eb685a47b75e9f35a77cce0a188aa1bb 478 Pfam PF00860 Permease family 19 431 4.2E-28 T 09-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 UA74_RS13195 309b6d01d0246bbbbb2905d2aa84556e 65 Pfam PF04149 Domain of unknown function (DUF397) 9 58 1.7E-8 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS01500 fb891c6a3d362362a233b5458bcb3a03 61 Pfam PF04149 Domain of unknown function (DUF397) 7 59 9.0E-19 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS30360 0b92c20f35b49ccdaf5cf173e5b176fc 203 Gene3D G3DSA:4.10.1080.10 121 194 8.2E-5 T 09-03-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 UA74_RS02765 49e914553d64ac392dc3fb587b4b7a54 153 Pfam PF08592 Domain of unknown function (DUF1772) 6 142 3.1E-17 T 09-03-2017 IPR013901 Protein of unknown function DUF1772 UA74_RS25920 242ea2f2c2040f93d9b1c3715d58c140 247 Pfam PF10067 Predicted membrane protein (DUF2306) 59 208 4.2E-39 T 09-03-2017 IPR018750 Protein of unknown function DUF2306, membrane UA74_RS24520 061cdb6e9590ae10add583d3b9cf7565 357 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 141 355 4.7E-32 T 09-03-2017 IPR015402 Protein of unknown function DUF1980 UA74_RS05230 6b90597e70830329d3c3c30ed714dd9c 338 Pfam PF00487 Fatty acid desaturase 61 297 6.7E-33 T 09-03-2017 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_RS12700 e7813988e2169f06621aed8672bdbd33 239 SUPERFAMILY SSF53137 95 222 5.36E-21 T 09-03-2017 UA74_RS23610 97f38a253bc557d4c37d89fcf72b53b6 140 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 20 135 9.6E-33 T 09-03-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III UA74_RS24360 c976b824075f299f2ffd05c3e4205ae3 405 Pfam PF04235 Protein of unknown function (DUF418) 232 394 2.4E-38 T 09-03-2017 IPR007349 Domain of unknown function DUF418 UA74_RS25125 c94d4a8f236c55503d76359ade3f96e9 264 Pfam PF14011 EspG family 15 256 1.4E-48 T 09-03-2017 IPR025734 EspG family UA74_RS15905 f259bbf7becc99c826264dff2fff1b7f 245 Pfam PF01881 CRISPR associated protein Cas6 100 243 5.1E-8 T 09-03-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 UA74_RS11635 06094f1bd23238792ad8a68d8dbc097d 265 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 3 256 4.0E-19 T 09-03-2017 UA74_RS23215 9fca320cafb70c48829382eb75c5e511 180 Pfam PF13374 Tetratricopeptide repeat 91 131 1.1E-7 T 09-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 UA74_RS15835 7645c1ba0c3d3425d01b36cad48b8173 219 Pfam PF02698 DUF218 domain 32 145 2.1E-18 T 09-03-2017 IPR003848 Domain of unknown function DUF218 UA74_RS15835 7645c1ba0c3d3425d01b36cad48b8173 219 Gene3D G3DSA:3.40.50.620 21 154 2.3E-40 T 09-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_RS10875 f0936ef024e1691799cf9dda1aa6c3a0 77 SUPERFAMILY SSF47598 1 54 3.67E-8 T 09-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 UA74_RS18335 38688b7f446e5e6af421a99ff517b34d 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 8.0E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS16330 73de447f3f304e5ac942c4650aa42747 269 SUPERFAMILY SSF53335 135 184 8.82E-5 T 09-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_RS30350 623c2b918266230a6ea778bff0cad02a 130 Pfam PF13630 SdpI/YhfL protein family 25 89 9.8E-11 T 09-03-2017 IPR025962 SdpI/YhfL protein family UA74_RS21045 db24b0955cdb0f5cbfad02753e606e52 63 Pfam PF04149 Domain of unknown function (DUF397) 6 57 4.2E-18 T 09-03-2017 IPR007278 Domain of unknown function DUF397 UA74_RS00955 4b6c4a21fd8853c7d4124bcd9d076146 468 Pfam PF01566 Natural resistance-associated macrophage protein 57 399 4.7E-18 T 09-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 UA74_RS13315 3d13e60e74ef6f7da53c4317a1031b1d 319 Pfam PF03601 Conserved hypothetical protein 698 3 300 1.6E-68 T 09-03-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 UA74_RS13625 005a3adf63bd25d823c4052eb0bd8dcc 89 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 78 2.9E-11 T 09-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020