locus-tag	class	description
UA75_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UA75_RS00015	COG0592	DNA-directed DNA polymerase activity
UA75_RS00020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
UA75_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UA75_RS00030	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
UA75_RS00035	COG0187	DNA topoisomerase II activity
UA75_RS00075	COG2311	Membrane
UA75_RS00105	COG3764	Sortase (surface protein transpeptidase)
UA75_RS00125	COG0515	serine threonine protein kinase
UA75_RS00125	COG2815	serine threonine protein kinase
UA75_RS00130	COG0515	serine threonine protein kinase
UA75_RS00135	COG0768	penicillin binding
UA75_RS00150	COG1716	ATPase activity
UA75_RS00155	COG1716	ATPase activity
UA75_RS00170	COG0018	arginyl-trna synthetase
UA75_RS00190	COG1309	transcriptional regulator
UA75_RS00220	COG2372	response to copper ion
UA75_RS00220	COG1276	copper resistance
UA75_RS00240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
UA75_RS00255	COG1174	glycine betaine transport
UA75_RS00280	COG0667	Aldo Keto reductase
UA75_RS00310	COG0438	transferase activity, transferring glycosyl groups
UA75_RS00325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UA75_RS00330	COG4115	mRNA cleavage
UA75_RS00335	COG2161	toxin-antitoxin pair type II binding
UA75_RS00355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UA75_RS00375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
UA75_RS00405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UA75_RS00415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UA75_RS00425	COG3279	Response regulator of the LytR AlgR family
UA75_RS00435	COG3275	phosphorelay sensor kinase activity
UA75_RS00455	COG0653	protein targeting
UA75_RS00490	COG1528	Iron-storage protein
UA75_RS00495	COG2235	arginine
UA75_RS00540	COG1271	oxidase subunit
UA75_RS00550	COG1294	oxidase, subunit
UA75_RS00555	COG4988	ABC transporter
UA75_RS00575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
UA75_RS00605	COG0754	glutathionylspermidine amidase activity
UA75_RS00610	COG3766	membrane
UA75_RS00630	COG0561	phosphatase activity
UA75_RS00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UA75_RS00665	COG0579	oxidoreductase
UA75_RS00680	COG1216	Glycosyl transferase, family 2
UA75_RS00690	COG1216	Glycosyl transferase, family 2
UA75_RS00720	COG0604	alcohol dehydrogenase
UA75_RS00725	COG2234	aminopeptidase activity
UA75_RS00785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
UA75_RS00795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UA75_RS00825	COG0183	Belongs to the thiolase family
UA75_RS00835	COG0287	Prephenate dehydrogenase
UA75_RS00845	COG0590	tRNA wobble adenosine to inosine editing
UA75_RS00870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
UA75_RS00895	COG1349	DNA-binding transcription factor activity
UA75_RS00900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UA75_RS00915	COG0601	transmembrane transport
UA75_RS00920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS00925	COG0444	Belongs to the ABC transporter superfamily
UA75_RS00935	COG0667	Aldo Keto reductase
UA75_RS00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UA75_RS00955	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS00960	COG1914	H( )-stimulated, divalent metal cation uptake system
UA75_RS00980	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS00985	COG1129	ABC transporter
UA75_RS01010	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
UA75_RS01015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
UA75_RS01025	COG0747	negative chemotaxis
UA75_RS01030	COG0601	transmembrane transport
UA75_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS01040	COG0444	Belongs to the ABC transporter superfamily
UA75_RS01045	COG4608	Belongs to the ABC transporter superfamily
UA75_RS01105	COG1764	response to oxidative stress
UA75_RS01115	COG3469	chitinase activity
UA75_RS01130	COG3591	Belongs to the peptidase S1B family
UA75_RS01145	COG1408	metallophosphoesterase
UA75_RS01160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UA75_RS01160	COG4499	WXG100 protein secretion system (Wss), protein YukC
UA75_RS01200	COG0673	inositol 2-dehydrogenase activity
UA75_RS01220	COG0592	DNA-directed DNA polymerase activity
UA75_RS01260	COG0596	Alpha beta hydrolase
UA75_RS01270	COG0730	response to heat
UA75_RS01295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UA75_RS01300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
UA75_RS01310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
UA75_RS01315	COG1737	Transcriptional regulator
UA75_RS01340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
UA75_RS01345	COG3876	Protein conserved in bacteria
UA75_RS01350	COG1472	Belongs to the glycosyl hydrolase 3 family
UA75_RS01400	COG1205	dead DEAH box helicase
UA75_RS01400	COG1111	helicase
UA75_RS01405	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
UA75_RS01415	COG1754	DNA topoisomerase type I activity
UA75_RS01415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UA75_RS01425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
UA75_RS01430	COG0470	DNA polymerase III
UA75_RS01440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UA75_RS01450	COG0587	DNA-directed DNA polymerase activity
UA75_RS01455	COG3973	AAA domain
UA75_RS01475	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
UA75_RS01485	COG2027	D-alanyl-D-alanine carboxypeptidase
UA75_RS01510	COG0037	tRNA processing
UA75_RS01520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UA75_RS01525	COG0302	gtp cyclohydrolase
UA75_RS01530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UA75_RS01570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
UA75_RS01575	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
UA75_RS01580	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
UA75_RS01585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
UA75_RS01610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
UA75_RS01625	COG1194	a g-specific adenine glycosylase
UA75_RS01635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
UA75_RS01645	COG1329	Transcriptional regulator
UA75_RS01650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
UA75_RS01665	COG0215	cysteine-tRNA ligase activity
UA75_RS01715	COG0483	inositol monophosphate 1-phosphatase activity
UA75_RS01725	COG2226	methyltransferase
UA75_RS01735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UA75_RS01740	COG3842	ATPase activity
UA75_RS01745	COG0803	Belongs to the bacterial solute-binding protein 9 family
UA75_RS01750	COG3842	ATPase activity
UA75_RS01755	COG3833	ABC-type maltose transport systems, permease component
UA75_RS01775	COG1609	Transcriptional regulator
UA75_RS01785	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
UA75_RS01800	COG0667	Aldo Keto reductase
UA75_RS01805	COG0456	acetyltransferase
UA75_RS01810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
UA75_RS01815	COG1917	Cupin 2, conserved barrel domain protein
UA75_RS01820	COG5285	phytanoyl-CoA dioxygenase
UA75_RS01830	COG3629	intracellular signal transduction
UA75_RS01830	COG3903	Transcriptional regulator
UA75_RS01850	COG2186	Transcriptional regulator
UA75_RS01870	COG0242	peptide deformylase activity
UA75_RS01875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
UA75_RS01880	COG0351	phosphomethylpyrimidine kinase
UA75_RS01895	COG2022	thiamine diphosphate biosynthetic process
UA75_RS01905	COG2022	thiamine diphosphate biosynthetic process
UA75_RS01905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UA75_RS01910	COG0352	thiamine-phosphate diphosphorylase activity
UA75_RS01920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UA75_RS01950	COG2188	Transcriptional regulator
UA75_RS01960	COG1175	transmembrane transport
UA75_RS01965	COG0395	ABC-type sugar transport system, permease component
UA75_RS01970	COG1472	Belongs to the glycosyl hydrolase 3 family
UA75_RS01975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
UA75_RS01990	COG2197	response regulator
UA75_RS02000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
UA75_RS02005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
UA75_RS02080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
UA75_RS02125	COG0788	formyltetrahydrofolate deformylase activity
UA75_RS02130	COG1309	transcriptional regulator
UA75_RS02150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
UA75_RS02185	COG0477	Major facilitator Superfamily
UA75_RS02195	COG0438	transferase activity, transferring glycosyl groups
UA75_RS02205	COG0588	phosphoglycerate mutase activity
UA75_RS02230	COG0506	proline dehydrogenase activity
UA75_RS02235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
UA75_RS02270	COG1960	acyl-CoA dehydrogenase activity
UA75_RS02290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
UA75_RS02295	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
UA75_RS02310	COG0113	porphobilinogen synthase activity
UA75_RS02350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
UA75_RS02355	COG0406	alpha-ribazole phosphatase activity
UA75_RS02365	COG0515	serine threonine protein kinase
UA75_RS02365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UA75_RS02370	COG0785	Cytochrome C biogenesis protein
UA75_RS02380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UA75_RS02430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UA75_RS02470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
UA75_RS02490	COG3396	Phenylacetate-CoA oxygenase
UA75_RS02495	COG3460	Phenylacetate-CoA oxygenase
UA75_RS02500	COG3396	Phenylacetate-CoA oxygenase
UA75_RS02505	COG2151	metal-sulfur cluster biosynthetic enzyme
UA75_RS02510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UA75_RS02525	COG2226	methyltransferase
UA75_RS02540	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UA75_RS02545	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UA75_RS02550	COG0649	NAD binding
UA75_RS02560	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
UA75_RS02565	COG1034	ATP synthesis coupled electron transport
UA75_RS02570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
UA75_RS02575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UA75_RS02580	COG0839	Belongs to the complex I subunit 6 family
UA75_RS02585	COG0713	ATP synthesis coupled electron transport
UA75_RS02600	COG1007	ATP synthesis coupled electron transport
UA75_RS02605	COG0142	geranyltranstransferase activity
UA75_RS02625	COG1013	pyruvate-flavodoxin oxidoreductase activity
UA75_RS02630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
UA75_RS02630	COG0674	pyruvate-flavodoxin oxidoreductase activity
UA75_RS02635	COG1522	sequence-specific DNA binding
UA75_RS02640	COG1834	amidinotransferase
UA75_RS02645	COG2205	protein histidine kinase activity
UA75_RS02650	COG0745	RESPONSE REGULATOR receiver
UA75_RS02665	COG1136	(ABC) transporter
UA75_RS02665	COG0577	efflux transmembrane transporter activity
UA75_RS02670	COG0577	efflux transmembrane transporter activity
UA75_RS02670	COG1136	(ABC) transporter
UA75_RS02685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UA75_RS02735	COG0501	Belongs to the peptidase M48B family
UA75_RS02740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
UA75_RS02755	COG0702	epimerase
UA75_RS02815	COG1674	ftsk spoiiie
UA75_RS02865	COG1666	GTP binding
UA75_RS02885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UA75_RS02890	COG2030	dehydratase
UA75_RS02900	COG0436	Aminotransferase
UA75_RS02920	COG0081	regulation of translation
UA75_RS02930	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
UA75_RS02935	COG0222	ribosome binding
UA75_RS02940	COG0085	RNA polymerase activity
UA75_RS02945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
UA75_RS02980	COG2197	response regulator
UA75_RS02995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
UA75_RS03000	COG0049	tRNA binding
UA75_RS03005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
UA75_RS03010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UA75_RS03015	COG0051	transcription antitermination factor activity, RNA binding
UA75_RS03020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
UA75_RS03025	COG0088	Forms part of the polypeptide exit tunnel
UA75_RS03030	COG0089	rRNA binding
UA75_RS03035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UA75_RS03040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UA75_RS03045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
UA75_RS03050	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
UA75_RS03055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
UA75_RS03065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
UA75_RS03070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
UA75_RS03075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
UA75_RS03080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
UA75_RS03090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
UA75_RS03095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
UA75_RS03100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
UA75_RS03105	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
UA75_RS03165	COG2226	methyltransferase
UA75_RS03180	COG0563	adenylate kinase activity
UA75_RS03200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
UA75_RS03205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
UA75_RS03210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UA75_RS03215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
UA75_RS03220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UA75_RS03225	COG0202	RNA polymerase activity
UA75_RS03230	COG0203	ribosomal protein L17
UA75_RS03235	COG0101	tRNA pseudouridine synthase activity
UA75_RS03255	COG4585	Histidine kinase
UA75_RS03260	COG3903	Transcriptional regulator
UA75_RS03260	COG3629	intracellular signal transduction
UA75_RS03265	COG0456	acetyltransferase
UA75_RS03295	COG2860	membrane
UA75_RS03300	COG0745	RESPONSE REGULATOR receiver
UA75_RS03305	COG2205	protein histidine kinase activity
UA75_RS03315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UA75_RS03320	COG0521	Mo-molybdopterin cofactor biosynthetic process
UA75_RS03320	COG0315	cyclic pyranopterin monophosphate synthase activity
UA75_RS03335	COG1970	mechanosensitive ion channel activity
UA75_RS03350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
UA75_RS03360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UA75_RS03370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UA75_RS03410	COG4989	oxidoreductase activity
UA75_RS03495	COG3850	Histidine kinase
UA75_RS03520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UA75_RS03525	COG0084	hydrolase, TatD family'
UA75_RS03530	COG1652	LysM domain
UA75_RS03535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS03550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
UA75_RS03630	COG1595	DNA-templated transcription, initiation
UA75_RS03635	COG1252	NADH dehydrogenase
UA75_RS03640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
UA75_RS03645	COG2011	ABC-type metal ion transport system permease component
UA75_RS03650	COG1464	Belongs to the NlpA lipoprotein family
UA75_RS03665	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
UA75_RS03670	COG2814	Major facilitator Superfamily
UA75_RS03675	COG2211	Major facilitator Superfamily
UA75_RS03680	COG0488	(ABC) transporter
UA75_RS03705	COG0193	aminoacyl-tRNA hydrolase activity
UA75_RS03710	COG3599	regulation of cell shape
UA75_RS03720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
UA75_RS03735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
UA75_RS03755	COG1309	transcriptional regulator
UA75_RS03770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UA75_RS03790	COG2610	gluconate transmembrane transporter activity
UA75_RS03795	COG0129	dihydroxy-acid dehydratase activity
UA75_RS03805	COG4946	Tricorn protease homolog
UA75_RS03805	COG0793	Belongs to the peptidase S41A family
UA75_RS03830	COG0148	phosphopyruvate hydratase activity
UA75_RS03885	COG0714	Associated with various cellular activities
UA75_RS03900	COG1252	NADH dehydrogenase
UA75_RS03940	COG0183	Belongs to the thiolase family
UA75_RS03945	COG2755	lipolytic protein G-D-S-L family
UA75_RS03965	COG1414	Transcriptional regulator
UA75_RS03970	COG1196	nuclear chromosome segregation
UA75_RS03970	COG0741	lytic transglycosylase activity
UA75_RS03970	COG0739	heme binding
UA75_RS03990	COG1175	transmembrane transport
UA75_RS03995	COG0395	ABC-type sugar transport system, permease component
UA75_RS04010	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS04065	COG3386	PFAM SMP-30 Gluconolaconase
UA75_RS04075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
UA75_RS04095	COG3185	4-Hydroxyphenylpyruvate dioxygenase
UA75_RS04105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UA75_RS04115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
UA75_RS04125	COG2226	methyltransferase
UA75_RS04130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
UA75_RS04155	COG1733	regulation of RNA biosynthetic process
UA75_RS04160	COG1331	Highly conserved protein containing a thioredoxin domain
UA75_RS04190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
UA75_RS04200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UA75_RS04210	COG0584	glycerophosphoryl diester phosphodiesterase
UA75_RS04215	COG0114	fumarate hydratase activity
UA75_RS04220	COG0492	ferredoxin-NADP+ reductase activity
UA75_RS04265	COG1722	exodeoxyribonuclease VII activity
UA75_RS04275	COG1570	exodeoxyribonuclease VII activity
UA75_RS04300	COG0420	3'-5' exonuclease activity
UA75_RS04305	COG0419	ATPase involved in DNA repair
UA75_RS04320	COG0012	GTP binding
UA75_RS04385	COG2154	pterin-4-alpha-carbinolamine dehydratase
UA75_RS04395	COG4149	molybdate abc transporter
UA75_RS04400	COG3842	ATPase activity
UA75_RS04430	COG0477	Major facilitator Superfamily
UA75_RS04450	COG1131	(ABC) transporter
UA75_RS04460	COG0745	RESPONSE REGULATOR receiver
UA75_RS04465	COG2205	protein histidine kinase activity
UA75_RS04475	COG1217	gtp-binding protein TYPA
UA75_RS04495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS04505	COG4608	Belongs to the ABC transporter superfamily
UA75_RS04510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
UA75_RS04530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UA75_RS04545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UA75_RS04565	COG0655	NAD(P)H dehydrogenase (quinone) activity
UA75_RS04570	COG1611	Belongs to the LOG family
UA75_RS04575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UA75_RS04655	COG1024	Enoyl-CoA hydratase
UA75_RS04660	COG3327	negative regulation of DNA-templated transcription, initiation
UA75_RS04670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UA75_RS04675	COG0583	DNA-binding transcription factor activity
UA75_RS04680	COG2814	Major facilitator Superfamily
UA75_RS04685	COG0297	glycogen (starch) synthase activity
UA75_RS04690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
UA75_RS04695	COG4122	O-methyltransferase activity
UA75_RS04700	COG1595	DNA-templated transcription, initiation
UA75_RS04710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UA75_RS04715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UA75_RS04730	COG2301	Belongs to the HpcH HpaI aldolase family
UA75_RS04780	COG0598	Magnesium transport protein CorA
UA75_RS04795	COG0613	PHP domain protein
UA75_RS04825	COG0513	Belongs to the DEAD box helicase family
UA75_RS04845	COG2267	carboxylic ester hydrolase activity
UA75_RS04885	COG0210	DNA helicase
UA75_RS04905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UA75_RS04935	COG0612	Peptidase, M16
UA75_RS04980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
UA75_RS05000	COG3480	Lon protease (S16) C-terminal proteolytic domain
UA75_RS05010	COG1615	UPF0182 protein
UA75_RS05035	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
UA75_RS05040	COG2884	Cell division ATP-binding protein ftsE
UA75_RS05045	COG2177	Part of the ABC transporter FtsEX involved in
UA75_RS05055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
UA75_RS05080	COG0640	Transcriptional regulator
UA75_RS05085	COG0586	Pfam SNARE associated Golgi protein
UA75_RS05100	COG0737	Belongs to the 5'-nucleotidase family
UA75_RS05105	COG1643	Atp-dependent helicase
UA75_RS05110	COG2814	Major facilitator Superfamily
UA75_RS05130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UA75_RS05135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UA75_RS05145	COG1132	(ABC) transporter
UA75_RS05150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
UA75_RS05155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS05185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS05195	COG2264	protein methyltransferase activity
UA75_RS05220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS05230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS05245	COG1253	flavin adenine dinucleotide binding
UA75_RS05250	COG1131	(ABC) transporter
UA75_RS05260	COG3851	Histidine kinase
UA75_RS05265	COG2197	response regulator
UA75_RS05270	COG1335	isochorismatase
UA75_RS05275	COG0583	DNA-binding transcription factor activity
UA75_RS05280	COG2197	response regulator
UA75_RS05300	COG1733	regulation of RNA biosynthetic process
UA75_RS05305	COG0604	alcohol dehydrogenase
UA75_RS05305	COG3321	synthase
UA75_RS05335	COG2267	carboxylic ester hydrolase activity
UA75_RS05340	COG0596	Alpha beta hydrolase
UA75_RS05345	COG4585	Histidine kinase
UA75_RS05350	COG2197	response regulator
UA75_RS05360	COG4221	oxidoreductase activity
UA75_RS05430	COG1131	(ABC) transporter
UA75_RS05450	COG0477	Major facilitator Superfamily
UA75_RS05480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
UA75_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS05540	COG0583	DNA-binding transcription factor activity
UA75_RS05545	COG2226	methyltransferase
UA75_RS05555	COG0277	FAD linked oxidase domain protein
UA75_RS05560	COG0579	oxidoreductase
UA75_RS05655	COG1414	Transcriptional regulator
UA75_RS05660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
UA75_RS05665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UA75_RS05670	COG2815	serine threonine protein kinase
UA75_RS05670	COG0515	serine threonine protein kinase
UA75_RS05705	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
UA75_RS05720	COG1819	glycosyl
UA75_RS05755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UA75_RS05760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UA75_RS05765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
UA75_RS05770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UA75_RS05775	COG0778	Nitroreductase
UA75_RS05785	COG0596	Alpha beta hydrolase
UA75_RS05790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
UA75_RS05795	COG0736	holo-[acyl-carrier-protein] synthase activity
UA75_RS05820	COG1131	(ABC) transporter
UA75_RS05825	COG1511	domain protein
UA75_RS05825	COG0842	Transport permease protein
UA75_RS05845	COG2197	response regulator
UA75_RS05895	COG0702	epimerase
UA75_RS05900	COG2124	cytochrome p450
UA75_RS05910	COG1937	Protein conserved in bacteria
UA75_RS05920	COG2217	Heavy metal translocating P-type atpase
UA75_RS05940	COG0110	maltose O-acetyltransferase activity
UA75_RS05955	COG0006	proline dipeptidase activity
UA75_RS06085	COG0346	lactoylglutathione lyase activity
UA75_RS06090	COG2207	Transcriptional regulator
UA75_RS06115	COG2197	response regulator
UA75_RS06120	COG3851	Histidine kinase
UA75_RS06135	COG1136	(ABC) transporter
UA75_RS06140	COG0577	efflux transmembrane transporter activity
UA75_RS06165	COG2936	dipeptidyl-peptidase activity
UA75_RS06185	COG5001	Diguanylate cyclase
UA75_RS06200	COG3830	Belongs to the UPF0237 family
UA75_RS06200	COG0560	Phosphoserine phosphatase
UA75_RS06215	COG1268	BioY protein
UA75_RS06220	COG1335	isochorismatase
UA75_RS06230	COG0604	alcohol dehydrogenase
UA75_RS06240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
UA75_RS06255	COG3191	aminopeptidase activity
UA75_RS06285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
UA75_RS06295	COG0598	Magnesium transport protein CorA
UA75_RS06300	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
UA75_RS06305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
UA75_RS06320	COG0058	SHG alpha-glucan phosphorylase activity
UA75_RS06415	COG1119	ATPase activity
UA75_RS06425	COG2226	methyltransferase
UA75_RS06430	COG0110	maltose O-acetyltransferase activity
UA75_RS06435	COG3903	Transcriptional regulator
UA75_RS06435	COG3629	intracellular signal transduction
UA75_RS06455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UA75_RS06465	COG3467	pyridoxamine 5'-phosphate
UA75_RS06495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
UA75_RS06505	COG0482	sulfurtransferase activity
UA75_RS06530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UA75_RS06625	COG0488	(ABC) transporter
UA75_RS06640	COG2146	nitrite reductase [NAD(P)H] activity
UA75_RS06665	COG5297	Belongs to the glycosyl hydrolase family 6
UA75_RS06710	COG1376	ErfK ybiS ycfS ynhG family protein
UA75_RS06715	COG2124	cytochrome p450
UA75_RS06730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
UA75_RS06745	COG0318	PFAM AMP-dependent synthetase and ligase
UA75_RS06760	COG5006	permease, DMT superfamily
UA75_RS06770	COG0697	spore germination
UA75_RS06840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
UA75_RS06845	COG0596	Alpha beta hydrolase
UA75_RS06865	COG1309	transcriptional regulator
UA75_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS06900	COG1404	Belongs to the peptidase S8 family
UA75_RS06940	COG2814	Major facilitator Superfamily
UA75_RS06980	COG1917	Cupin 2, conserved barrel domain protein
UA75_RS06985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
UA75_RS07005	COG1595	DNA-templated transcription, initiation
UA75_RS07030	COG0018	arginyl-trna synthetase
UA75_RS07035	COG0019	diaminopimelate decarboxylase activity
UA75_RS07040	COG0460	homoserine dehydrogenase
UA75_RS07045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
UA75_RS07050	COG0083	homoserine kinase activity
UA75_RS07055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UA75_RS07055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UA75_RS07065	COG0254	rRNA binding
UA75_RS07070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UA75_RS07080	COG2890	protein-(glutamine-N5) methyltransferase activity
UA75_RS07095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
UA75_RS07100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
UA75_RS07110	COG0356	it plays a direct role in the translocation of protons across the membrane
UA75_RS07115	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
UA75_RS07120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
UA75_RS07125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
UA75_RS07130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
UA75_RS07135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
UA75_RS07150	COG1595	DNA-templated transcription, initiation
UA75_RS07155	COG0355	proton-transporting ATP synthase activity, rotational mechanism
UA75_RS07180	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
UA75_RS07185	COG0765	amino acid transport
UA75_RS07190	COG0765	amino acid transport
UA75_RS07195	COG1126	abc transporter atp-binding protein
UA75_RS07210	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
UA75_RS07235	COG2376	Dihydroxyacetone kinase
UA75_RS07245	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
UA75_RS07270	COG0346	lactoylglutathione lyase activity
UA75_RS07280	COG0183	Belongs to the thiolase family
UA75_RS07295	COG2409	Drug exporters of the RND superfamily
UA75_RS07300	COG1846	Transcriptional regulator
UA75_RS07310	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
UA75_RS07310	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
UA75_RS07335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
UA75_RS07340	COG0366	Alpha amylase catalytic
UA75_RS07355	COG1051	belongs to the nudix hydrolase family
UA75_RS07395	COG1472	Belongs to the glycosyl hydrolase 3 family
UA75_RS07400	COG1609	Transcriptional regulator
UA75_RS07415	COG4209	transmembrane transport
UA75_RS07420	COG0395	ABC-type sugar transport system, permease component
UA75_RS07450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS07465	COG0640	Transcriptional regulator
UA75_RS07520	COG4585	Histidine kinase
UA75_RS07525	COG2197	response regulator
UA75_RS07545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UA75_RS07565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
UA75_RS07570	COG3281	Trehalose synthase
UA75_RS07575	COG0366	Alpha amylase catalytic
UA75_RS07580	COG0366	Alpha amylase catalytic
UA75_RS07595	COG0667	Aldo Keto reductase
UA75_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS07650	COG0693	protein deglycase activity
UA75_RS07675	COG1309	transcriptional regulator
UA75_RS07680	COG2272	Belongs to the type-B carboxylesterase lipase family
UA75_RS07785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UA75_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS07840	COG3831	ATPase activity
UA75_RS07855	COG2205	protein histidine kinase activity
UA75_RS07860	COG0745	RESPONSE REGULATOR receiver
UA75_RS07925	COG2902	Dehydrogenase
UA75_RS07940	COG0366	Alpha amylase catalytic
UA75_RS07950	COG0668	transmembrane transport
UA75_RS07975	COG1505	serine-type exopeptidase activity
UA75_RS07995	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
UA75_RS08005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
UA75_RS08050	COG4552	Acetyltransferase involved in intracellular survival and related
UA75_RS08075	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
UA75_RS08090	COG1309	transcriptional regulator
UA75_RS08120	COG0544	peptidyl-prolyl cis-trans isomerase activity
UA75_RS08125	COG0740	serine-type endopeptidase activity
UA75_RS08130	COG0740	serine-type endopeptidase activity
UA75_RS08155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
UA75_RS08175	COG0525	valine-tRNA ligase activity
UA75_RS08180	COG0285	dihydrofolate synthase activity
UA75_RS08190	COG0105	UTP biosynthetic process
UA75_RS08200	COG0842	Transport permease protein
UA75_RS08205	COG0842	Transport permease protein
UA75_RS08215	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
UA75_RS08220	COG1404	Belongs to the peptidase S8 family
UA75_RS08235	COG1530	ribonuclease E activity
UA75_RS08235	COG1530	ribonuclease E activity
UA75_RS08260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
UA75_RS08270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UA75_RS08275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
UA75_RS08285	COG0514	ATP-dependent DNA helicase (RecQ)
UA75_RS08290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
UA75_RS08310	COG0799	negative regulation of ribosome biogenesis
UA75_RS08320	COG2755	lipolytic protein G-D-S-L family
UA75_RS08325	COG1307	EDD domain protein, DegV family
UA75_RS08330	COG1555	photosystem II stabilization
UA75_RS08340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
UA75_RS08350	COG0268	Binds directly to 16S ribosomal RNA
UA75_RS08365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UA75_RS08400	COG1490	D-aminoacyl-tRNA deacylase activity
UA75_RS08405	COG0318	PFAM AMP-dependent synthetase and ligase
UA75_RS08405	COG0204	Acyl-transferase
UA75_RS08420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UA75_RS08425	COG2313	pseudouridylate synthase activity
UA75_RS08460	COG4214	carbohydrate transport
UA75_RS08465	COG1940	carbohydrate kinase activity
UA75_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS08485	COG1940	carbohydrate kinase activity
UA75_RS08490	COG0483	inositol monophosphate 1-phosphatase activity
UA75_RS08510	COG0756	dUTP diphosphatase activity
UA75_RS08535	COG0569	domain protein
UA75_RS08540	COG0531	amino acid
UA75_RS08545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UA75_RS08550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
UA75_RS08555	COG0745	RESPONSE REGULATOR receiver
UA75_RS08560	COG2205	protein histidine kinase activity
UA75_RS08565	COG1231	oxidoreductase activity
UA75_RS08580	COG0481	GTPase activity
UA75_RS08585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
UA75_RS08590	COG2137	regulation of response to DNA damage stimulus
UA75_RS08600	COG0800	Aldolase
UA75_RS08620	COG0765	amino acid transport
UA75_RS08625	COG0765	amino acid transport
UA75_RS08635	COG1126	abc transporter atp-binding protein
UA75_RS08640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UA75_RS08650	COG1196	nuclear chromosome segregation
UA75_RS08660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
UA75_RS08675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
UA75_RS08685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
UA75_RS08695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UA75_RS08700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UA75_RS08735	COG2186	Transcriptional regulator
UA75_RS08740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UA75_RS08745	COG3395	kinase activity
UA75_RS08765	COG0823	Involved in the tonB-independent uptake of proteins
UA75_RS08765	COG1506	peptidase
UA75_RS08775	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
UA75_RS08795	COG0123	including yeast histone deacetylase and acetoin utilization protein
UA75_RS08815	COG5002	protein histidine kinase activity
UA75_RS08820	COG0745	RESPONSE REGULATOR receiver
UA75_RS08835	COG3265	gluconokinase activity
UA75_RS08870	COG0228	four-way junction DNA binding
UA75_RS08880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
UA75_RS08885	COG0336	Belongs to the RNA methyltransferase TrmD family
UA75_RS08890	COG0335	large ribosomal subunit rRNA binding
UA75_RS08895	COG0681	Belongs to the peptidase S26 family
UA75_RS08900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
UA75_RS08920	COG0601	transmembrane transport
UA75_RS08925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS08930	COG0444	Belongs to the ABC transporter superfamily
UA75_RS08935	COG4608	Belongs to the ABC transporter superfamily
UA75_RS08950	COG0792	nuclease activity
UA75_RS08970	COG1191	sigma factor activity
UA75_RS08985	COG0052	Belongs to the universal ribosomal protein uS2 family
UA75_RS08990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
UA75_RS08995	COG0528	UMP kinase activity
UA75_RS09000	COG0233	cytoplasmic translational termination
UA75_RS09010	COG2226	methyltransferase
UA75_RS09015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
UA75_RS09030	COG3842	ATPase activity
UA75_RS09040	COG1176	ABC-type spermidine putrescine transport system, permease component I
UA75_RS09045	COG1177	transmembrane transport
UA75_RS09050	COG2261	transglycosylase associated protein
UA75_RS09055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
UA75_RS09065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
UA75_RS09085	COG1492	cobalamin metabolic process
UA75_RS09105	COG2807	transmembrane transport
UA75_RS09120	COG1881	PFAM PEBP family protein
UA75_RS09130	COG4585	Histidine kinase
UA75_RS09135	COG2197	response regulator
UA75_RS09200	COG1648	precorrin-2 dehydrogenase activity
UA75_RS09200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
UA75_RS09205	COG0513	Belongs to the DEAD box helicase family
UA75_RS09215	COG3022	response to hydroperoxide
UA75_RS09225	COG0442	prolyl-tRNA aminoacylation
UA75_RS09235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UA75_RS09260	COG0779	Required for maturation of 30S ribosomal subunits
UA75_RS09275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
UA75_RS09285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
UA75_RS09290	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS09370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
UA75_RS09395	COG2146	nitrite reductase [NAD(P)H] activity
UA75_RS09395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UA75_RS09400	COG2146	nitrite reductase [NAD(P)H] activity
UA75_RS09400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UA75_RS09405	COG2223	nitrite transmembrane transporter activity
UA75_RS09410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UA75_RS09415	COG0243	molybdopterin cofactor binding
UA75_RS09420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
UA75_RS09425	COG1185	polyribonucleotide nucleotidyltransferase activity
UA75_RS09430	COG0612	Peptidase, M16
UA75_RS09435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
UA75_RS09460	COG2274	protein secretion by the type I secretion system
UA75_RS09490	COG3214	Protein conserved in bacteria
UA75_RS09505	COG1196	nuclear chromosome segregation
UA75_RS09505	COG0741	lytic transglycosylase activity
UA75_RS09505	COG0739	heme binding
UA75_RS09510	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
UA75_RS09515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UA75_RS09520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
UA75_RS09525	COG1674	ftsk spoiiie
UA75_RS09535	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
UA75_RS09545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UA75_RS09555	COG1546	Belongs to the CinA family
UA75_RS09555	COG1058	Belongs to the CinA family
UA75_RS09560	COG1396	sequence-specific DNA binding
UA75_RS09570	COG1842	Phage shock protein A
UA75_RS09580	COG2233	PERMEase
UA75_RS09585	COG1192	Involved in chromosome partitioning
UA75_RS09600	COG1305	Transglutaminase-like
UA75_RS09610	COG0714	Associated with various cellular activities
UA75_RS09620	COG2001	Belongs to the MraZ family
UA75_RS09625	COG0275	rRNA processing
UA75_RS09640	COG0768	penicillin binding
UA75_RS09655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
UA75_RS09660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
UA75_RS09670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
UA75_RS09675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UA75_RS09680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
UA75_RS09685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UA75_RS09695	COG1984	allophanate hydrolase subunit 2
UA75_RS09705	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
UA75_RS09715	COG1070	Carbohydrate kinase
UA75_RS09730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
UA75_RS09735	COG1799	cell septum assembly
UA75_RS09745	COG3599	regulation of cell shape
UA75_RS09750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
UA75_RS09780	COG1309	transcriptional regulator
UA75_RS09805	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS09815	COG2124	cytochrome p450
UA75_RS09820	COG2124	cytochrome p450
UA75_RS09825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
UA75_RS09830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UA75_RS09840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
UA75_RS09865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
UA75_RS09870	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
UA75_RS09905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS09915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
UA75_RS09920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
UA75_RS09925	COG2318	DinB family
UA75_RS09945	COG0446	pyridine nucleotide-disulphide oxidoreductase
UA75_RS09955	COG0131	Imidazoleglycerol-phosphate dehydratase
UA75_RS09965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
UA75_RS09975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
UA75_RS09995	COG0107	imidazoleglycerol-phosphate synthase activity
UA75_RS10005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
UA75_RS10050	COG1309	transcriptional regulator
UA75_RS10065	COG0134	indole-3-glycerol-phosphate synthase activity
UA75_RS10070	COG0133	tryptophan synthase activity
UA75_RS10075	COG0159	tryptophan synthase activity
UA75_RS10085	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
UA75_RS10090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
UA75_RS10100	COG1160	GTP binding
UA75_RS10130	COG2188	Transcriptional regulator
UA75_RS10140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UA75_RS10145	COG1280	lysine exporter protein (LysE YggA)
UA75_RS10170	COG0142	geranyltranstransferase activity
UA75_RS10195	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS10200	COG0179	Fumarylacetoacetate (FAA) hydrolase
UA75_RS10220	COG0110	maltose O-acetyltransferase activity
UA75_RS10260	COG0732	type I restriction modification DNA specificity domain
UA75_RS10270	COG0515	serine threonine protein kinase
UA75_RS10270	COG2815	serine threonine protein kinase
UA75_RS10285	COG4941	Belongs to the sigma-70 factor family
UA75_RS10290	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
UA75_RS10305	COG1733	regulation of RNA biosynthetic process
UA75_RS10310	COG0671	phosphoesterase, PA-phosphatase related
UA75_RS10320	COG0741	lytic transglycosylase activity
UA75_RS10320	COG1196	nuclear chromosome segregation
UA75_RS10320	COG0739	heme binding
UA75_RS10325	COG0154	amidase activity
UA75_RS10335	COG1522	sequence-specific DNA binding
UA75_RS10345	COG0156	8-amino-7-oxononanoate synthase activity
UA75_RS10375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
UA75_RS10375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
UA75_RS10410	COG0438	transferase activity, transferring glycosyl groups
UA75_RS10425	COG1088	dTDP-glucose 4,6-dehydratase activity
UA75_RS10430	COG2192	nodulation
UA75_RS10435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UA75_RS10440	COG0859	PFAM glycosyl transferase family 9
UA75_RS10445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UA75_RS10450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
UA75_RS10450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
UA75_RS10455	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS10465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
UA75_RS10485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UA75_RS10490	COG0789	Transcriptional regulator
UA75_RS10495	COG0659	secondary active sulfate transmembrane transporter activity
UA75_RS10510	COG0667	Aldo Keto reductase
UA75_RS10545	COG0589	response to stress
UA75_RS10560	COG0514	ATP-dependent DNA helicase (RecQ)
UA75_RS10575	COG1966	Carbon starvation protein
UA75_RS10585	COG0003	Pfam Anion-transporting ATPase
UA75_RS10600	COG1120	ATPase activity
UA75_RS10680	COG5001	Diguanylate cyclase
UA75_RS10695	COG0270	DNA (cytosine-5-)-methyltransferase activity
UA75_RS10755	COG2050	protein possibly involved in aromatic compounds catabolism
UA75_RS10785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UA75_RS10790	COG0539	negative regulation of cytoplasmic translation
UA75_RS10795	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UA75_RS10795	COG2755	lipolytic protein G-D-S-L family
UA75_RS10800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UA75_RS10800	COG2755	lipolytic protein G-D-S-L family
UA75_RS10805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
UA75_RS10805	COG0237	dephospho-CoA kinase activity
UA75_RS10835	COG1131	(ABC) transporter
UA75_RS10845	COG1228	amidohydrolase
UA75_RS10850	COG1506	peptidase
UA75_RS10850	COG0823	Involved in the tonB-independent uptake of proteins
UA75_RS10850	COG4946	Tricorn protease homolog
UA75_RS10890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UA75_RS10895	COG1560	Kdo2-lipid A biosynthetic process
UA75_RS10900	COG0438	transferase activity, transferring glycosyl groups
UA75_RS10905	COG1051	belongs to the nudix hydrolase family
UA75_RS10920	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
UA75_RS10935	COG1396	sequence-specific DNA binding
UA75_RS10950	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
UA75_RS10955	COG0217	transcriptional regulatory protein
UA75_RS10965	COG3629	intracellular signal transduction
UA75_RS10970	COG3629	intracellular signal transduction
UA75_RS10970	COG3903	Transcriptional regulator
UA75_RS10975	COG2124	cytochrome p450
UA75_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS10995	COG2132	Multicopper oxidase
UA75_RS11005	COG3104	oligopeptide transport
UA75_RS11020	COG2084	Dehydrogenase
UA75_RS11035	COG0475	glutathione-regulated potassium exporter activity
UA75_RS11040	COG2345	Transcriptional regulator
UA75_RS11045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UA75_RS11050	COG2345	Transcriptional regulator
UA75_RS11075	COG0702	epimerase
UA75_RS11100	COG0367	asparagine synthase
UA75_RS11105	COG1819	glycosyl
UA75_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS11125	COG0662	Cupin 2, conserved barrel domain protein
UA75_RS11130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UA75_RS11135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UA75_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS11170	COG0825	malonyl-CoA metabolic process
UA75_RS11170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
UA75_RS11175	COG0511	ligase activity, forming carbon-carbon bonds
UA75_RS11180	COG0439	Biotin carboxylase
UA75_RS11200	COG0346	lactoylglutathione lyase activity
UA75_RS11205	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
UA75_RS11210	COG0632	four-way junction helicase activity
UA75_RS11215	COG2255	four-way junction helicase activity
UA75_RS11225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UA75_RS11230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UA75_RS11235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UA75_RS11275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UA75_RS11285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
UA75_RS11290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
UA75_RS11320	COG1404	Belongs to the peptidase S8 family
UA75_RS11320	COG4412	M6 family metalloprotease domain protein
UA75_RS11325	COG1404	Belongs to the peptidase S8 family
UA75_RS11325	COG4412	M6 family metalloprotease domain protein
UA75_RS11355	COG4412	M6 family metalloprotease domain protein
UA75_RS11355	COG1404	Belongs to the peptidase S8 family
UA75_RS11370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UA75_RS11380	COG1733	regulation of RNA biosynthetic process
UA75_RS11390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UA75_RS11395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UA75_RS11395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UA75_RS11400	COG0803	Belongs to the bacterial solute-binding protein 9 family
UA75_RS11405	COG1121	(ABC) transporter
UA75_RS11410	COG1321	iron dependent repressor
UA75_RS11410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UA75_RS11415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UA75_RS11420	COG2132	Multicopper oxidase
UA75_RS11425	COG1309	transcriptional regulator
UA75_RS11440	COG1607	acyl-coa hydrolase
UA75_RS11445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
UA75_RS11460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UA75_RS11485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UA75_RS11505	COG1716	ATPase activity
UA75_RS11525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UA75_RS11525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UA75_RS11530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
UA75_RS11550	COG3104	oligopeptide transport
UA75_RS11555	COG1309	transcriptional regulator
UA75_RS11560	COG3572	ergothioneine biosynthetic process
UA75_RS11565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UA75_RS11570	COG0121	glutamine amidotransferase
UA75_RS11575	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
UA75_RS11595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
UA75_RS11615	COG0791	NLP P60 protein
UA75_RS11615	COG3883	PFAM NLP P60 protein
UA75_RS11620	COG0583	DNA-binding transcription factor activity
UA75_RS11625	COG0697	spore germination
UA75_RS11640	COG0714	Associated with various cellular activities
UA75_RS11650	COG2304	oxidoreductase activity
UA75_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS11665	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
UA75_RS11670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
UA75_RS11715	COG1012	belongs to the aldehyde dehydrogenase family
UA75_RS11750	COG3473	Maleate cis-trans isomerase
UA75_RS11760	COG2186	Transcriptional regulator
UA75_RS11770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
UA75_RS11780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UA75_RS11805	COG1716	ATPase activity
UA75_RS11825	COG0183	Belongs to the thiolase family
UA75_RS11830	COG1253	flavin adenine dinucleotide binding
UA75_RS11845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UA75_RS11850	COG0297	glycogen (starch) synthase activity
UA75_RS11895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UA75_RS11900	COG0542	response to heat
UA75_RS11955	COG1653	transport
UA75_RS11965	COG2186	Transcriptional regulator
UA75_RS11970	COG3401	FG-GAP repeat protein
UA75_RS12050	COG0508	dehydrogenase complex catalyzes the overall conversion of
UA75_RS12055	COG0022	dehydrogenase e1 component
UA75_RS12060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
UA75_RS12065	COG0789	Transcriptional regulator
UA75_RS12085	COG1643	Atp-dependent helicase
UA75_RS12105	COG2259	Doxx family
UA75_RS12120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
UA75_RS12130	COG0662	Cupin 2, conserved barrel domain protein
UA75_RS12175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UA75_RS12190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
UA75_RS12230	COG1263	PTS System
UA75_RS12235	COG2188	Transcriptional regulator
UA75_RS12240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UA75_RS12240	COG1263	PTS System
UA75_RS12245	COG2190	(PTS) system
UA75_RS12255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
UA75_RS12260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UA75_RS12270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
UA75_RS12275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
UA75_RS12280	COG0346	lactoylglutathione lyase activity
UA75_RS12300	COG0006	proline dipeptidase activity
UA75_RS12305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
UA75_RS12310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UA75_RS12320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
UA75_RS12325	COG0540	Belongs to the ATCase OTCase family
UA75_RS12340	COG0505	Belongs to the CarA family
UA75_RS12350	COG0284	orotidine-5'-phosphate decarboxylase activity
UA75_RS12365	COG1758	RNA polymerase activity
UA75_RS12375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
UA75_RS12410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UA75_RS12415	COG0242	peptide deformylase activity
UA75_RS12430	COG2040	homocysteine
UA75_RS12445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UA75_RS12445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UA75_RS12450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
UA75_RS12465	COG0322	excinuclease ABC activity
UA75_RS12470	COG1660	Displays ATPase and GTPase activities
UA75_RS12480	COG1481	regulation of sporulation
UA75_RS12485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
UA75_RS12490	COG0126	phosphoglycerate kinase activity
UA75_RS12495	COG0149	triose-phosphate isomerase activity
UA75_RS12500	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
UA75_RS12530	COG0363	glucosamine-6-phosphate deaminase activity
UA75_RS12545	COG0166	Belongs to the GPI family
UA75_RS12550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UA75_RS12560	COG0109	protoheme IX farnesyltransferase activity
UA75_RS12590	COG0477	Major facilitator Superfamily
UA75_RS12620	COG1510	regulation of RNA biosynthetic process
UA75_RS12635	COG1131	(ABC) transporter
UA75_RS12660	COG2146	nitrite reductase [NAD(P)H] activity
UA75_RS12665	COG0396	ATPase activity
UA75_RS12680	COG2151	metal-sulfur cluster biosynthetic enzyme
UA75_RS12700	COG2200	EAL domain
UA75_RS12720	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS12750	COG0488	(ABC) transporter
UA75_RS12760	COG1024	Enoyl-CoA hydratase
UA75_RS12770	COG1733	regulation of RNA biosynthetic process
UA75_RS12805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UA75_RS12835	COG1063	alcohol dehydrogenase
UA75_RS12870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UA75_RS12880	COG1657	PFAM Prenyltransferase squalene oxidase
UA75_RS12885	COG0142	geranyltranstransferase activity
UA75_RS12910	COG0515	serine threonine protein kinase
UA75_RS12920	COG1505	serine-type exopeptidase activity
UA75_RS12930	COG0140	phosphoribosyl-ATP diphosphatase activity
UA75_RS12935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
UA75_RS12940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
UA75_RS12945	COG2329	Antibiotic biosynthesis monooxygenase
UA75_RS12950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
UA75_RS12990	COG1222	aaa ATPase
UA75_RS13020	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
UA75_RS13025	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
UA75_RS13040	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
UA75_RS13050	COG2378	regulation of single-species biofilm formation
UA75_RS13080	COG4552	Acetyltransferase involved in intracellular survival and related
UA75_RS13115	COG1136	(ABC) transporter
UA75_RS13120	COG1136	(ABC) transporter
UA75_RS13120	COG0577	efflux transmembrane transporter activity
UA75_RS13130	COG3030	protein affecting phage T7 exclusion by the F plasmid
UA75_RS13135	COG1574	metal-dependent hydrolase with the TIM-barrel fold
UA75_RS13145	COG0745	RESPONSE REGULATOR receiver
UA75_RS13165	COG0667	Aldo Keto reductase
UA75_RS13205	COG3845	ABC transporter
UA75_RS13215	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
UA75_RS13280	COG3285	dna ligase
UA75_RS13280	COG1793	dna ligase
UA75_RS13290	COG0517	IMP dehydrogenase activity
UA75_RS13305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
UA75_RS13315	COG0385	Bile acid
UA75_RS13335	COG0515	serine threonine protein kinase
UA75_RS13345	COG1132	(ABC) transporter
UA75_RS13350	COG1132	(ABC) transporter
UA75_RS13355	COG2855	membrane
UA75_RS13365	COG4607	ABC-type enterochelin transport system periplasmic component
UA75_RS13370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS13375	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS13380	COG1120	ATPase activity
UA75_RS13385	COG1132	(ABC) transporter
UA75_RS13390	COG1132	(ABC) transporter
UA75_RS13455	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UA75_RS13460	COG1309	transcriptional regulator
UA75_RS13470	COG1879	ABC-type sugar transport system periplasmic component
UA75_RS13475	COG1129	ABC transporter
UA75_RS13480	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS13485	COG1063	alcohol dehydrogenase
UA75_RS13500	COG2186	Transcriptional regulator
UA75_RS13505	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS13510	COG0800	Aldolase
UA75_RS13515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UA75_RS13520	COG1309	transcriptional regulator
UA75_RS13530	COG2318	DinB family
UA75_RS13540	COG1396	sequence-specific DNA binding
UA75_RS13570	COG0583	DNA-binding transcription factor activity
UA75_RS13590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UA75_RS13600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
UA75_RS13615	COG1846	Transcriptional regulator
UA75_RS13635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
UA75_RS13650	COG4221	oxidoreductase activity
UA75_RS13690	COG1960	acyl-CoA dehydrogenase activity
UA75_RS13695	COG0318	PFAM AMP-dependent synthetase and ligase
UA75_RS13710	COG2508	Transcriptional regulator
UA75_RS13725	COG0183	Belongs to the thiolase family
UA75_RS13730	COG1960	acyl-CoA dehydrogenase activity
UA75_RS13755	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
UA75_RS13760	COG0235	Class ii aldolase
UA75_RS13765	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
UA75_RS13770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
UA75_RS13785	COG1079	Belongs to the binding-protein-dependent transport system permease family
UA75_RS13790	COG1079	Belongs to the binding-protein-dependent transport system permease family
UA75_RS13795	COG3845	ABC transporter
UA75_RS13820	COG0583	DNA-binding transcription factor activity
UA75_RS13825	COG1309	transcriptional regulator
UA75_RS13830	COG1132	(ABC) transporter
UA75_RS13850	COG2018	Roadblock/LC7 domain
UA75_RS13865	COG1595	DNA-templated transcription, initiation
UA75_RS13960	COG1518	maintenance of DNA repeat elements
UA75_RS13965	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
UA75_RS14000	COG3467	pyridoxamine 5'-phosphate
UA75_RS14025	COG0673	inositol 2-dehydrogenase activity
UA75_RS14030	COG1116	anion transmembrane transporter activity
UA75_RS14040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UA75_RS14065	COG3629	intracellular signal transduction
UA75_RS14065	COG3903	Transcriptional regulator
UA75_RS14095	COG0477	Major facilitator Superfamily
UA75_RS14100	COG2362	D-Aminopeptidase
UA75_RS14110	COG0601	transmembrane transport
UA75_RS14115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS14135	COG1278	Cold shock
UA75_RS14145	COG2264	protein methyltransferase activity
UA75_RS14155	COG1619	proteins homologs of microcin C7 resistance protein MccF
UA75_RS14205	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
UA75_RS14225	COG2197	response regulator
UA75_RS14230	COG4585	Histidine kinase
UA75_RS14265	COG0215	cysteine-tRNA ligase activity
UA75_RS14280	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
UA75_RS14285	COG2076	Multidrug Resistance protein
UA75_RS14295	COG0646	methionine synthase
UA75_RS14295	COG1410	methionine synthase
UA75_RS14305	COG0546	phosphoglycolate phosphatase activity
UA75_RS14315	COG0372	Belongs to the citrate synthase family
UA75_RS14330	COG1515	deoxyribonuclease V activity
UA75_RS14335	COG0242	peptide deformylase activity
UA75_RS14345	COG0640	Transcriptional regulator
UA75_RS14355	COG0477	Major facilitator Superfamily
UA75_RS14360	COG1132	(ABC) transporter
UA75_RS14385	COG0235	Class ii aldolase
UA75_RS14390	COG3395	kinase activity
UA75_RS14405	COG1349	DNA-binding transcription factor activity
UA75_RS14420	COG1309	transcriptional regulator
UA75_RS14430	COG3384	dioxygenase
UA75_RS14470	COG1396	sequence-specific DNA binding
UA75_RS14530	COG1484	DNA-dependent DNA replication
UA75_RS14535	COG0305	Participates in initiation and elongation during chromosome replication
UA75_RS14915	COG2814	Major facilitator Superfamily
UA75_RS14930	COG0076	glutamate decarboxylase activity
UA75_RS14960	COG3525	Glycosyl hydrolase, family 20, catalytic domain
UA75_RS14960	COG3291	Pkd domain containing protein
UA75_RS14985	COG0277	FAD linked oxidase domain protein
UA75_RS14990	COG1686	Belongs to the peptidase S11 family
UA75_RS15010	COG1012	belongs to the aldehyde dehydrogenase family
UA75_RS15035	COG1785	Belongs to the alkaline phosphatase family
UA75_RS15045	COG0009	L-threonylcarbamoyladenylate synthase
UA75_RS15050	COG1120	ATPase activity
UA75_RS15055	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS15060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS15090	COG0477	Major facilitator Superfamily
UA75_RS15100	COG1309	transcriptional regulator
UA75_RS15105	COG2027	D-alanyl-D-alanine carboxypeptidase
UA75_RS15110	COG0488	(ABC) transporter
UA75_RS15115	COG0583	DNA-binding transcription factor activity
UA75_RS15140	COG1063	alcohol dehydrogenase
UA75_RS15150	COG0400	carboxylic ester hydrolase activity
UA75_RS15155	COG0346	lactoylglutathione lyase activity
UA75_RS15160	COG0655	NAD(P)H dehydrogenase (quinone) activity
UA75_RS15165	COG1846	Transcriptional regulator
UA75_RS15170	COG1649	PFAM Uncharacterised BCR, COG1649
UA75_RS15185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UA75_RS15245	COG2267	carboxylic ester hydrolase activity
UA75_RS15250	COG2226	methyltransferase
UA75_RS15255	COG0488	(ABC) transporter
UA75_RS15260	COG1739	Uncharacterized protein family UPF0029
UA75_RS15305	COG0463	Glycosyl transferase, family 2
UA75_RS15315	COG1435	thymidine kinase activity
UA75_RS15320	COG2270	Major facilitator Superfamily
UA75_RS15335	COG5001	Diguanylate cyclase
UA75_RS15335	COG3300	MHYT domain
UA75_RS15350	COG4974	Belongs to the 'phage' integrase family
UA75_RS15375	COG3903	Transcriptional regulator
UA75_RS15375	COG3629	intracellular signal transduction
UA75_RS15435	COG0702	epimerase
UA75_RS15460	COG1132	(ABC) transporter
UA75_RS15465	COG1132	(ABC) transporter
UA75_RS15490	COG0492	ferredoxin-NADP+ reductase activity
UA75_RS15500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UA75_RS15520	COG0789	Transcriptional regulator
UA75_RS15535	COG1960	acyl-CoA dehydrogenase activity
UA75_RS15545	COG1846	Transcriptional regulator
UA75_RS15550	COG0446	pyridine nucleotide-disulphide oxidoreductase
UA75_RS15565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UA75_RS15570	COG0702	epimerase
UA75_RS15590	COG0477	Major facilitator Superfamily
UA75_RS15615	COG0702	epimerase
UA75_RS15620	COG1733	regulation of RNA biosynthetic process
UA75_RS15630	COG1309	transcriptional regulator
UA75_RS15645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UA75_RS15650	COG1357	PFAM Pentapeptide repeats (8 copies)
UA75_RS15655	COG1309	transcriptional regulator
UA75_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS15705	COG0739	heme binding
UA75_RS15705	COG0741	lytic transglycosylase activity
UA75_RS15705	COG1196	nuclear chromosome segregation
UA75_RS15720	COG1309	transcriptional regulator
UA75_RS15780	COG2267	carboxylic ester hydrolase activity
UA75_RS15790	COG1309	transcriptional regulator
UA75_RS15810	COG4941	Belongs to the sigma-70 factor family
UA75_RS15815	COG3795	YCII-related domain
UA75_RS15825	COG0346	lactoylglutathione lyase activity
UA75_RS15855	COG0697	spore germination
UA75_RS15865	COG2205	protein histidine kinase activity
UA75_RS15870	COG2197	response regulator
UA75_RS15895	COG3795	YCII-related domain
UA75_RS15900	COG4941	Belongs to the sigma-70 factor family
UA75_RS15905	COG0477	Major facilitator Superfamily
UA75_RS15950	COG3795	YCII-related domain
UA75_RS15965	COG1309	transcriptional regulator
UA75_RS15970	COG0583	DNA-binding transcription factor activity
UA75_RS15975	COG0439	Biotin carboxylase
UA75_RS16000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UA75_RS16020	COG0477	Major facilitator Superfamily
UA75_RS16025	COG0596	Alpha beta hydrolase
UA75_RS16025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UA75_RS16040	COG0667	Aldo Keto reductase
UA75_RS16050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UA75_RS16055	COG2365	Tyrosine phosphatase family
UA75_RS16060	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
UA75_RS16075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UA75_RS16085	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
UA75_RS16090	COG2890	protein-(glutamine-N5) methyltransferase activity
UA75_RS16095	COG0519	Catalyzes the synthesis of GMP from XMP
UA75_RS16140	COG2249	NAD(P)H dehydrogenase (quinone) activity
UA75_RS16145	COG0667	Aldo Keto reductase
UA75_RS16170	COG1902	pentaerythritol trinitrate reductase activity
UA75_RS16185	COG1968	undecaprenyl-diphosphatase activity
UA75_RS16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UA75_RS16210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UA75_RS16275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UA75_RS16355	COG1401	restriction endodeoxyribonuclease activity
UA75_RS16395	COG0717	Belongs to the dCTP deaminase family
UA75_RS16410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
UA75_RS16430	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
UA75_RS16455	COG0406	alpha-ribazole phosphatase activity
UA75_RS16475	COG1216	Glycosyl transferase, family 2
UA75_RS16540	COG3706	GGDEF domain
UA75_RS16625	COG0714	Associated with various cellular activities
UA75_RS16670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UA75_RS16715	COG2124	cytochrome p450
UA75_RS16720	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
UA75_RS16725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS16740	COG0644	oxidoreductase
UA75_RS16750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS16785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS16790	COG2124	cytochrome p450
UA75_RS16820	COG1250	3-hydroxyacyl-CoA dehydrogenase
UA75_RS16825	COG3321	synthase
UA75_RS16825	COG0604	alcohol dehydrogenase
UA75_RS16830	COG0604	alcohol dehydrogenase
UA75_RS16830	COG3321	synthase
UA75_RS16870	COG0667	Aldo Keto reductase
UA75_RS16935	COG2801	Transposase and inactivated derivatives
UA75_RS16970	COG1819	glycosyl
UA75_RS16975	COG0604	alcohol dehydrogenase
UA75_RS16975	COG3321	synthase
UA75_RS16990	COG3321	synthase
UA75_RS16990	COG0604	alcohol dehydrogenase
UA75_RS16995	COG0604	alcohol dehydrogenase
UA75_RS16995	COG3321	synthase
UA75_RS17100	COG1132	(ABC) transporter
UA75_RS17140	COG0601	transmembrane transport
UA75_RS17150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
UA75_RS17175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UA75_RS17190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UA75_RS17200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
UA75_RS17210	COG1349	DNA-binding transcription factor activity
UA75_RS17220	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
UA75_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS17265	COG2072	flavoprotein involved in K transport
UA75_RS17305	COG0477	Major facilitator Superfamily
UA75_RS17365	COG0300	oxidoreductase activity
UA75_RS17395	COG1131	(ABC) transporter
UA75_RS17415	COG3012	SEC-C Motif Domain Protein
UA75_RS17420	COG1131	(ABC) transporter
UA75_RS17465	COG1609	Transcriptional regulator
UA75_RS17470	COG1233	COG1233 Phytoene dehydrogenase and related
UA75_RS17495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS17500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UA75_RS17505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UA75_RS17515	COG3938	Belongs to the proline racemase family
UA75_RS17535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UA75_RS17540	COG1802	Transcriptional regulator
UA75_RS17560	COG0444	Belongs to the ABC transporter superfamily
UA75_RS17570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS17575	COG0747	negative chemotaxis
UA75_RS17585	COG3509	depolymerase
UA75_RS17585	COG3693	PFAM glycoside hydrolase, family 10
UA75_RS17610	COG1056	cytidyltransferase-related domain
UA75_RS17610	COG1051	belongs to the nudix hydrolase family
UA75_RS17615	COG1056	cytidyltransferase-related domain
UA75_RS17615	COG1051	belongs to the nudix hydrolase family
UA75_RS17630	COG0698	ribose 5-phosphate isomerase
UA75_RS17640	COG0137	argininosuccinate synthase activity
UA75_RS17655	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
UA75_RS17655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UA75_RS17655	COG3321	synthase
UA75_RS17655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UA75_RS17675	COG2423	ornithine cyclodeaminase activity
UA75_RS17680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UA75_RS17700	COG0010	Belongs to the arginase family
UA75_RS17715	COG1120	ATPase activity
UA75_RS17720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS17730	COG3336	cytochrome c oxidase
UA75_RS17760	COG3401	FG-GAP repeat protein
UA75_RS17785	COG3973	AAA domain
UA75_RS17790	COG1819	glycosyl
UA75_RS17815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UA75_RS17830	COG2197	response regulator
UA75_RS17835	COG0604	alcohol dehydrogenase
UA75_RS17835	COG3321	synthase
UA75_RS17850	COG0604	alcohol dehydrogenase
UA75_RS17850	COG3321	synthase
UA75_RS17855	COG2814	Major facilitator Superfamily
UA75_RS17900	COG2072	flavoprotein involved in K transport
UA75_RS17940	COG0477	Major facilitator Superfamily
UA75_RS17950	COG0583	DNA-binding transcription factor activity
UA75_RS17975	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS17990	COG0326	Molecular chaperone. Has ATPase activity
UA75_RS18005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
UA75_RS18015	COG2124	cytochrome p450
UA75_RS18040	COG0640	Transcriptional regulator
UA75_RS18065	COG0596	Alpha beta hydrolase
UA75_RS18070	COG0477	Major facilitator Superfamily
UA75_RS18090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UA75_RS18105	COG2124	cytochrome p450
UA75_RS18165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UA75_RS18185	COG1335	isochorismatase
UA75_RS18190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
UA75_RS18200	COG1032	radical SAM domain protein
UA75_RS18215	COG0489	protein tyrosine kinase activity
UA75_RS18220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UA75_RS18225	COG1309	transcriptional regulator
UA75_RS18235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
UA75_RS18240	COG1595	DNA-templated transcription, initiation
UA75_RS18295	COG1131	(ABC) transporter
UA75_RS18305	COG2197	response regulator
UA75_RS18315	COG1309	transcriptional regulator
UA75_RS18330	COG3507	Belongs to the glycosyl hydrolase 43 family
UA75_RS18355	COG1175	transmembrane transport
UA75_RS18365	COG1609	Transcriptional regulator
UA75_RS18385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UA75_RS18390	COG0431	NADPH-dependent FMN reductase
UA75_RS18405	COG0789	Transcriptional regulator
UA75_RS18410	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
UA75_RS18435	COG2391	methyltransferase activity
UA75_RS18475	COG2130	NADP-dependent
UA75_RS18480	COG1233	COG1233 Phytoene dehydrogenase and related
UA75_RS18505	COG0702	epimerase
UA75_RS18540	COG2267	carboxylic ester hydrolase activity
UA75_RS18550	COG1309	transcriptional regulator
UA75_RS18555	COG2409	Drug exporters of the RND superfamily
UA75_RS18560	COG1902	pentaerythritol trinitrate reductase activity
UA75_RS18565	COG0789	Transcriptional regulator
UA75_RS18575	COG0366	Alpha amylase catalytic
UA75_RS18630	COG4585	Histidine kinase
UA75_RS18655	COG0395	ABC-type sugar transport system, permease component
UA75_RS18660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
UA75_RS18665	COG1609	Transcriptional regulator
UA75_RS18695	COG1755	Isoprenylcysteine carboxyl methyltransferase
UA75_RS18710	COG0523	cobalamin synthesis protein
UA75_RS18720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS18735	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS18740	COG1129	ABC transporter
UA75_RS18750	COG2186	Transcriptional regulator
UA75_RS18755	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS18790	COG1063	alcohol dehydrogenase
UA75_RS18795	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS18820	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS18825	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS18830	COG1129	ABC transporter
UA75_RS18835	COG1879	ABC-type sugar transport system periplasmic component
UA75_RS18840	COG3250	beta-galactosidase activity
UA75_RS18845	COG1349	DNA-binding transcription factor activity
UA75_RS18865	COG3629	intracellular signal transduction
UA75_RS18865	COG3903	Transcriptional regulator
UA75_RS18880	COG0667	Aldo Keto reductase
UA75_RS18930	COG0564	pseudouridine synthase activity
UA75_RS18945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS19080	COG2188	Transcriptional regulator
UA75_RS19100	COG4941	Belongs to the sigma-70 factor family
UA75_RS19135	COG2124	cytochrome p450
UA75_RS19195	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
UA75_RS19200	COG3959	Transketolase, thiamine diphosphate binding domain
UA75_RS19205	COG3958	Transketolase
UA75_RS19220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
UA75_RS19270	COG1653	transport
UA75_RS19275	COG1175	transmembrane transport
UA75_RS19280	COG0395	ABC-type sugar transport system, permease component
UA75_RS19290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UA75_RS19295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UA75_RS19310	COG1414	Transcriptional regulator
UA75_RS19315	COG2182	Extracellular solute-binding protein
UA75_RS19320	COG1175	transmembrane transport
UA75_RS19330	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS19345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UA75_RS19355	COG0740	serine-type endopeptidase activity
UA75_RS19365	COG0583	DNA-binding transcription factor activity
UA75_RS19370	COG5006	permease, DMT superfamily
UA75_RS19375	COG1609	Transcriptional regulator
UA75_RS19410	COG0395	ABC-type sugar transport system, permease component
UA75_RS19415	COG1175	transmembrane transport
UA75_RS19445	COG3467	pyridoxamine 5'-phosphate
UA75_RS19475	COG0346	lactoylglutathione lyase activity
UA75_RS19480	COG0640	Transcriptional regulator
UA75_RS19490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UA75_RS19495	COG0456	acetyltransferase
UA75_RS19495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
UA75_RS19540	COG1120	ATPase activity
UA75_RS19545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS19560	COG0653	protein targeting
UA75_RS19565	COG0702	epimerase
UA75_RS19570	COG0443	Heat shock 70 kDa protein
UA75_RS19655	COG1205	dead DEAH box helicase
UA75_RS19655	COG1111	helicase
UA75_RS19665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UA75_RS19680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
UA75_RS19695	COG0300	oxidoreductase activity
UA75_RS19710	COG1863	multisubunit Na H antiporter MnhE subunit
UA75_RS19715	COG0651	ATP synthesis coupled electron transport
UA75_RS19720	COG1006	Multisubunit Na H antiporter MnhC subunit
UA75_RS19725	COG2111	Na H antiporter
UA75_RS19725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
UA75_RS19740	COG1131	(ABC) transporter
UA75_RS19745	COG0569	domain protein
UA75_RS19750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
UA75_RS19755	COG2205	protein histidine kinase activity
UA75_RS19760	COG0745	RESPONSE REGULATOR receiver
UA75_RS19770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
UA75_RS19815	COG2409	Drug exporters of the RND superfamily
UA75_RS19880	COG0129	dihydroxy-acid dehydratase activity
UA75_RS19915	COG2076	Multidrug Resistance protein
UA75_RS19920	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS19925	COG1309	transcriptional regulator
UA75_RS19945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS19950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS19975	COG2261	transglycosylase associated protein
UA75_RS19990	COG0714	Associated with various cellular activities
UA75_RS19995	COG3552	Protein containing von Willebrand factor type A (VWA) domain
UA75_RS20020	COG0477	Major facilitator Superfamily
UA75_RS20030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
UA75_RS20035	COG0798	PFAM Bile acid sodium symporter
UA75_RS20040	COG0640	Transcriptional regulator
UA75_RS20045	COG0492	ferredoxin-NADP+ reductase activity
UA75_RS20075	COG1063	alcohol dehydrogenase
UA75_RS20080	COG0395	ABC-type sugar transport system, permease component
UA75_RS20085	COG1175	transmembrane transport
UA75_RS20095	COG0800	Aldolase
UA75_RS20125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
UA75_RS20130	COG4335	DNA alkylation repair
UA75_RS20160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UA75_RS20165	COG1120	ATPase activity
UA75_RS20170	COG0028	Belongs to the TPP enzyme family
UA75_RS20190	COG1032	radical SAM domain protein
UA75_RS20200	COG2124	cytochrome p450
UA75_RS20240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
UA75_RS20250	COG0640	Transcriptional regulator
UA75_RS20255	COG1250	3-hydroxyacyl-CoA dehydrogenase
UA75_RS20330	COG0277	FAD linked oxidase domain protein
UA75_RS20330	COG0247	lactate metabolic process
UA75_RS20345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS20365	COG1105	Belongs to the carbohydrate kinase PfkB family
UA75_RS20390	COG2814	Major facilitator Superfamily
UA75_RS20425	COG3831	ATPase activity
UA75_RS20435	COG3831	ATPase activity
UA75_RS20440	COG0714	Associated with various cellular activities
UA75_RS20445	COG2425	protein containing a von Willebrand factor type A (vWA) domain
UA75_RS20450	COG3552	Protein containing von Willebrand factor type A (VWA) domain
UA75_RS20455	COG4715	Zinc finger, swim domain protein
UA75_RS20460	COG2197	response regulator
UA75_RS20480	COG2267	carboxylic ester hydrolase activity
UA75_RS20520	COG2186	Transcriptional regulator
UA75_RS20530	COG2376	Dihydroxyacetone kinase
UA75_RS20535	COG0698	ribose 5-phosphate isomerase
UA75_RS20540	COG0149	triose-phosphate isomerase activity
UA75_RS20545	COG1082	Xylose isomerase domain protein TIM barrel
UA75_RS20550	COG2084	Dehydrogenase
UA75_RS20560	COG2706	6-phosphogluconolactonase activity
UA75_RS20570	COG1921	L-seryl-tRNASec selenium transferase activity
UA75_RS20585	COG3842	ATPase activity
UA75_RS20645	COG1846	Transcriptional regulator
UA75_RS20650	COG0596	Alpha beta hydrolase
UA75_RS20695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS20700	COG0405	Gamma-glutamyltransferase
UA75_RS20730	COG1660	Displays ATPase and GTPase activities
UA75_RS20855	COG2124	cytochrome p450
UA75_RS20865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS20870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS20875	COG4592	Periplasmic binding protein
UA75_RS20885	COG2318	DinB family
UA75_RS20890	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS20895	COG1309	transcriptional regulator
UA75_RS20915	COG0510	thiamine kinase activity
UA75_RS20920	COG3250	beta-galactosidase activity
UA75_RS20965	COG1278	Cold shock
UA75_RS20970	COG3226	Transcriptional regulator
UA75_RS20985	COG2515	1-aminocyclopropane-1-carboxylate deaminase
UA75_RS21000	COG0583	DNA-binding transcription factor activity
UA75_RS21005	COG2267	carboxylic ester hydrolase activity
UA75_RS21020	COG2368	4-hydroxyphenylacetate
UA75_RS21035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
UA75_RS21040	COG3473	Maleate cis-trans isomerase
UA75_RS21050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
UA75_RS21055	COG1404	Belongs to the peptidase S8 family
UA75_RS21080	COG0515	serine threonine protein kinase
UA75_RS21080	COG2815	serine threonine protein kinase
UA75_RS21110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UA75_RS21145	COG3940	Belongs to the glycosyl hydrolase 43 family
UA75_RS21160	COG1432	Conserved Protein
UA75_RS21165	COG1063	alcohol dehydrogenase
UA75_RS21170	COG0247	lactate metabolic process
UA75_RS21175	COG1139	Iron-sulfur cluster binding protein
UA75_RS21180	COG1556	Lactate utilization protein
UA75_RS21185	COG0494	nUDIX hydrolase
UA75_RS21200	COG0745	RESPONSE REGULATOR receiver
UA75_RS21205	COG2205	protein histidine kinase activity
UA75_RS21215	COG2755	lipolytic protein G-D-S-L family
UA75_RS21215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UA75_RS21250	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS21255	COG1129	ABC transporter
UA75_RS21330	COG0525	valine-tRNA ligase activity
UA75_RS21335	COG1136	(ABC) transporter
UA75_RS21335	COG0577	efflux transmembrane transporter activity
UA75_RS21340	COG0577	efflux transmembrane transporter activity
UA75_RS21340	COG1136	(ABC) transporter
UA75_RS21360	COG0464	growth
UA75_RS21375	COG4946	Tricorn protease homolog
UA75_RS21375	COG1506	peptidase
UA75_RS21375	COG0823	Involved in the tonB-independent uptake of proteins
UA75_RS21390	COG2890	protein-(glutamine-N5) methyltransferase activity
UA75_RS21395	COG3629	intracellular signal transduction
UA75_RS21395	COG3903	Transcriptional regulator
UA75_RS21450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS21520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UA75_RS21530	COG0438	transferase activity, transferring glycosyl groups
UA75_RS21535	COG1940	carbohydrate kinase activity
UA75_RS21550	COG1082	Xylose isomerase domain protein TIM barrel
UA75_RS21555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UA75_RS21560	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
UA75_RS21565	COG0745	RESPONSE REGULATOR receiver
UA75_RS21570	COG4733	cellulase activity
UA75_RS21570	COG5297	Belongs to the glycosyl hydrolase family 6
UA75_RS21580	COG2723	6-phospho-beta-galactosidase activity
UA75_RS21585	COG0395	ABC-type sugar transport system, permease component
UA75_RS21610	COG1620	l-lactate permease
UA75_RS21620	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS21625	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
UA75_RS21640	COG2226	methyltransferase
UA75_RS21650	COG0254	rRNA binding
UA75_RS21670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
UA75_RS21675	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UA75_RS21680	COG0656	L-ascorbic acid biosynthetic process
UA75_RS21690	COG0438	transferase activity, transferring glycosyl groups
UA75_RS21695	COG1309	transcriptional regulator
UA75_RS21700	COG1131	(ABC) transporter
UA75_RS21720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UA75_RS21740	COG0739	heme binding
UA75_RS21765	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
UA75_RS21770	COG0473	3-isopropylmalate dehydrogenase activity
UA75_RS21775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UA75_RS21780	COG0586	Pfam SNARE associated Golgi protein
UA75_RS21785	COG0659	secondary active sulfate transmembrane transporter activity
UA75_RS21805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
UA75_RS21810	COG0076	glutamate decarboxylase activity
UA75_RS21820	COG1946	Acyl-CoA thioesterase
UA75_RS21835	COG2234	aminopeptidase activity
UA75_RS21850	COG0067	glutamate synthase
UA75_RS21850	COG0070	glutamate synthase
UA75_RS21850	COG0069	glutamate synthase activity
UA75_RS21855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UA75_RS21865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS21870	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
UA75_RS21890	COG0022	dehydrogenase e1 component
UA75_RS21900	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
UA75_RS21900	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
UA75_RS21965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
UA75_RS21970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
UA75_RS21985	COG0702	epimerase
UA75_RS22000	COG4585	Histidine kinase
UA75_RS22005	COG2197	response regulator
UA75_RS22030	COG0494	nUDIX hydrolase
UA75_RS22035	COG0504	CTP synthase activity
UA75_RS22055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
UA75_RS22070	COG0647	UMP catabolic process
UA75_RS22105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
UA75_RS22110	COG2094	Belongs to the DNA glycosylase MPG family
UA75_RS22115	COG0165	Argininosuccinate lyase
UA75_RS22125	COG1438	arginine binding
UA75_RS22130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
UA75_RS22140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UA75_RS22145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
UA75_RS22150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
UA75_RS22180	COG0072	phenylalanine-tRNA ligase activity
UA75_RS22180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UA75_RS22185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
UA75_RS22195	COG3550	peptidyl-serine autophosphorylation
UA75_RS22200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UA75_RS22205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
UA75_RS22210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
UA75_RS22255	COG0328	RNA-DNA hybrid ribonuclease activity
UA75_RS22275	COG2356	endonuclease I
UA75_RS22310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UA75_RS22315	COG1929	Belongs to the glycerate kinase type-1 family
UA75_RS22330	COG2205	protein histidine kinase activity
UA75_RS22390	COG4221	oxidoreductase activity
UA75_RS22400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UA75_RS22450	COG0640	Transcriptional regulator
UA75_RS22485	COG0778	Nitroreductase
UA75_RS22505	COG1595	DNA-templated transcription, initiation
UA75_RS22600	COG0667	Aldo Keto reductase
UA75_RS22640	COG3226	Transcriptional regulator
UA75_RS22645	COG0738	Major facilitator superfamily
UA75_RS22660	COG0673	inositol 2-dehydrogenase activity
UA75_RS22680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS22685	COG0601	transmembrane transport
UA75_RS22690	COG0747	negative chemotaxis
UA75_RS22695	COG0673	inositol 2-dehydrogenase activity
UA75_RS22710	COG1609	Transcriptional regulator
UA75_RS22715	COG0246	Mannitol dehydrogenase
UA75_RS22720	COG2721	sulfolactate sulfo-lyase activity
UA75_RS22730	COG0363	glucosamine-6-phosphate deaminase activity
UA75_RS22735	COG2267	carboxylic ester hydrolase activity
UA75_RS22740	COG1309	transcriptional regulator
UA75_RS22760	COG1120	ATPase activity
UA75_RS22775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS22790	COG2357	RelA SpoT domain protein
UA75_RS22805	COG2186	Transcriptional regulator
UA75_RS22820	COG1175	transmembrane transport
UA75_RS22825	COG0395	ABC-type sugar transport system, permease component
UA75_RS22840	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS22845	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS22865	COG0183	Belongs to the thiolase family
UA75_RS22875	COG2271	Major facilitator Superfamily
UA75_RS22885	COG0596	Alpha beta hydrolase
UA75_RS22890	COG1309	transcriptional regulator
UA75_RS22910	COG0702	epimerase
UA75_RS22930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UA75_RS22930	COG0515	serine threonine protein kinase
UA75_RS22935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UA75_RS22950	COG0210	DNA helicase
UA75_RS22975	COG2197	response regulator
UA75_RS22980	COG4585	Histidine kinase
UA75_RS22990	COG2132	Multicopper oxidase
UA75_RS23005	COG2124	cytochrome p450
UA75_RS23010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
UA75_RS23025	COG2315	Protein conserved in bacteria
UA75_RS23030	COG0542	response to heat
UA75_RS23055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UA75_RS23060	COG0747	negative chemotaxis
UA75_RS23070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS23075	COG0444	Belongs to the ABC transporter superfamily
UA75_RS23080	COG4608	Belongs to the ABC transporter superfamily
UA75_RS23100	COG1733	regulation of RNA biosynthetic process
UA75_RS23105	COG1414	Transcriptional regulator
UA75_RS23110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS23160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
UA75_RS23205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UA75_RS23215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UA75_RS23220	COG0583	DNA-binding transcription factor activity
UA75_RS23225	COG0747	negative chemotaxis
UA75_RS23235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UA75_RS23245	COG4608	Belongs to the ABC transporter superfamily
UA75_RS23260	COG0640	Transcriptional regulator
UA75_RS23270	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS23285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UA75_RS23295	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS23305	COG1414	Transcriptional regulator
UA75_RS23315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UA75_RS23330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UA75_RS23340	COG2271	Major facilitator Superfamily
UA75_RS23350	COG0583	DNA-binding transcription factor activity
UA75_RS23355	COG2814	Major facilitator Superfamily
UA75_RS23365	COG0667	Aldo Keto reductase
UA75_RS23445	COG2814	Major facilitator Superfamily
UA75_RS23470	COG0477	Major facilitator Superfamily
UA75_RS23475	COG0477	Major facilitator Superfamily
UA75_RS23495	COG2390	Transcriptional regulator
UA75_RS23500	COG1063	alcohol dehydrogenase
UA75_RS23515	COG0395	ABC-type sugar transport system, permease component
UA75_RS23545	COG2205	protein histidine kinase activity
UA75_RS23550	COG0590	tRNA wobble adenosine to inosine editing
UA75_RS23550	COG0037	tRNA processing
UA75_RS23570	COG2124	cytochrome p450
UA75_RS23595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
UA75_RS23640	COG3629	intracellular signal transduction
UA75_RS23640	COG3903	Transcriptional regulator
UA75_RS23670	COG1857	crispr-associated protein
UA75_RS23710	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
UA75_RS23730	COG0477	Major facilitator Superfamily
UA75_RS23780	COG1857	crispr-associated protein
UA75_RS23810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UA75_RS23820	COG2183	response to ionizing radiation
UA75_RS23845	COG4257	antibiotic catabolic process
UA75_RS23880	COG4585	Histidine kinase
UA75_RS23885	COG2197	response regulator
UA75_RS23890	COG1271	oxidase subunit
UA75_RS23900	COG4988	ABC transporter
UA75_RS23905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
UA75_RS23930	COG3401	FG-GAP repeat protein
UA75_RS23985	COG2375	cellular response to nickel ion
UA75_RS24085	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UA75_RS24095	COG0693	protein deglycase activity
UA75_RS24120	COG3473	Maleate cis-trans isomerase
UA75_RS24145	COG0248	Ppx GppA phosphatase
UA75_RS24150	COG3842	ATPase activity
UA75_RS24170	COG1609	Transcriptional regulator
UA75_RS24220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UA75_RS24230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UA75_RS24270	COG1793	dna ligase
UA75_RS24285	COG0124	histidyl-tRNA synthetase
UA75_RS24300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UA75_RS24310	COG3253	May function as heme-dependent peroxidase
UA75_RS24315	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
UA75_RS24320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
UA75_RS24330	COG2197	response regulator
UA75_RS24345	COG0183	Belongs to the thiolase family
UA75_RS24350	COG1250	3-hydroxyacyl-CoA dehydrogenase
UA75_RS24350	COG1024	Enoyl-CoA hydratase
UA75_RS24365	COG4948	Mandelate Racemase Muconate Lactonizing
UA75_RS24370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UA75_RS24380	COG0673	inositol 2-dehydrogenase activity
UA75_RS24385	COG1653	transport
UA75_RS24390	COG1175	transmembrane transport
UA75_RS24395	COG0395	ABC-type sugar transport system, permease component
UA75_RS24410	COG3866	Pectate lyase
UA75_RS24435	COG1653	transport
UA75_RS24440	COG1070	Carbohydrate kinase
UA75_RS24450	COG3347	Dehydrogenase
UA75_RS24450	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS24455	COG4952	isomerase
UA75_RS24465	COG1609	Transcriptional regulator
UA75_RS24475	COG0673	inositol 2-dehydrogenase activity
UA75_RS24520	COG5297	Belongs to the glycosyl hydrolase family 6
UA75_RS24525	COG2176	DNA-directed DNA polymerase activity
UA75_RS24545	COG0823	Involved in the tonB-independent uptake of proteins
UA75_RS24545	COG1506	peptidase
UA75_RS24555	COG2197	response regulator
UA75_RS24575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UA75_RS24580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UA75_RS24585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UA75_RS24595	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
UA75_RS24600	COG0167	dihydroorotate dehydrogenase activity
UA75_RS24625	COG0543	2 iron, 2 sulfur cluster binding
UA75_RS24630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
UA75_RS24665	COG2132	Multicopper oxidase
UA75_RS24715	COG0583	DNA-binding transcription factor activity
UA75_RS24725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UA75_RS24730	COG1609	Transcriptional regulator
UA75_RS24770	COG1609	Transcriptional regulator
UA75_RS24775	COG1609	Transcriptional regulator
UA75_RS24795	COG1175	transmembrane transport
UA75_RS24800	COG0395	ABC-type sugar transport system, permease component
UA75_RS24835	COG0395	ABC-type sugar transport system, permease component
UA75_RS24840	COG4209	transmembrane transport
UA75_RS24845	COG0405	Gamma-glutamyltransferase
UA75_RS24945	COG2311	Membrane
UA75_RS24965	COG2197	response regulator
UA75_RS24970	COG4585	Histidine kinase
UA75_RS24980	COG1131	(ABC) transporter
UA75_RS24990	COG4977	sequence-specific DNA binding
UA75_RS25005	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS25015	COG0596	Alpha beta hydrolase
UA75_RS25035	COG4106	trans-aconitate 2-methyltransferase activity
UA75_RS25045	COG0358	DNA primase activity
UA75_RS25050	COG1595	DNA-templated transcription, initiation
UA75_RS25060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
UA75_RS25070	COG3340	Belongs to the peptidase S51 family
UA75_RS25075	COG0423	glycine-tRNA ligase activity
UA75_RS25110	COG0701	Predicted permease
UA75_RS25120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
UA75_RS25145	COG1131	(ABC) transporter
UA75_RS25150	COG2188	Transcriptional regulator
UA75_RS25155	COG1381	Involved in DNA repair and RecF pathway recombination
UA75_RS25160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
UA75_RS25180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
UA75_RS25190	COG0537	adenosine 5'-monophosphoramidase activity
UA75_RS25200	COG0484	heat shock protein binding
UA75_RS25205	COG1420	regulation of RNA biosynthetic process
UA75_RS25215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UA75_RS25245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
UA75_RS25280	COG2732	(Barnase) inhibitor
UA75_RS25290	COG0604	alcohol dehydrogenase
UA75_RS25320	COG0443	Heat shock 70 kDa protein
UA75_RS25325	COG1201	RNA secondary structure unwinding
UA75_RS25375	COG0142	geranyltranstransferase activity
UA75_RS25395	COG2815	serine threonine protein kinase
UA75_RS25395	COG0515	serine threonine protein kinase
UA75_RS25405	COG2268	Band 7 protein
UA75_RS25425	COG0584	glycerophosphoryl diester phosphodiesterase
UA75_RS25465	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
UA75_RS25555	COG0003	Pfam Anion-transporting ATPase
UA75_RS25580	COG0438	transferase activity, transferring glycosyl groups
UA75_RS25590	COG0791	NLP P60 protein
UA75_RS25610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
UA75_RS25625	COG2010	Cytochrome c
UA75_RS25630	COG1845	cytochrome c oxidase, subunit III
UA75_RS25645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
UA75_RS25655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
UA75_RS25705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UA75_RS25730	COG0667	Aldo Keto reductase
UA75_RS25745	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
UA75_RS25750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
UA75_RS25755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UA75_RS25760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
UA75_RS25770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UA75_RS25780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UA75_RS25785	COG0508	dehydrogenase complex catalyzes the overall conversion of
UA75_RS25795	COG0321	lipoyl(octanoyl) transferase activity
UA75_RS25810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
UA75_RS25825	COG0174	glutamine synthetase
UA75_RS25845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
UA75_RS25850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UA75_RS25850	COG0519	Catalyzes the synthesis of GMP from XMP
UA75_RS25875	COG0174	glutamine synthetase
UA75_RS25885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UA75_RS25885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
UA75_RS25890	COG2318	DinB family
UA75_RS25895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
UA75_RS25905	COG0435	Glutathione S-transferase
UA75_RS25935	COG0791	NLP P60 protein
UA75_RS25935	COG3883	PFAM NLP P60 protein
UA75_RS26045	COG1064	alcohol dehydrogenase
UA75_RS26070	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
UA75_RS26085	COG2239	Acts as a magnesium transporter
UA75_RS26165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UA75_RS26170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UA75_RS26245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
UA75_RS26250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UA75_RS26285	COG1254	Belongs to the acylphosphatase family
UA75_RS26290	COG2340	Cysteine-rich secretory protein family
UA75_RS26310	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
UA75_RS26315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
UA75_RS26320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
UA75_RS26330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
UA75_RS26335	COG0571	ribonuclease III activity
UA75_RS26340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
UA75_RS26360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
UA75_RS26365	COG0742	ribosomal rna small subunit methyltransferase
UA75_RS26385	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
UA75_RS26400	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
UA75_RS26455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
UA75_RS26465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
UA75_RS26475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
UA75_RS26495	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
UA75_RS26520	COG1725	Transcriptional regulator
UA75_RS26540	COG1131	(ABC) transporter
UA75_RS26560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UA75_RS26575	COG0626	cystathionine gamma-synthase activity
UA75_RS26580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
UA75_RS26590	COG1920	GTP binding
UA75_RS26600	COG0406	alpha-ribazole phosphatase activity
UA75_RS26600	COG0494	nUDIX hydrolase
UA75_RS26610	COG0066	3-isopropylmalate dehydratase activity
UA75_RS26615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UA75_RS26640	COG1011	Hydrolase
UA75_RS26645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UA75_RS26655	COG0179	Fumarylacetoacetate (FAA) hydrolase
UA75_RS26675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UA75_RS26680	COG0473	3-isopropylmalate dehydrogenase activity
UA75_RS26685	COG1404	Belongs to the peptidase S8 family
UA75_RS26700	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
UA75_RS26705	COG0440	acetolactate synthase activity
UA75_RS26720	COG0129	dihydroxy-acid dehydratase activity
UA75_RS26745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UA75_RS26745	COG0515	serine threonine protein kinase
UA75_RS26755	COG2259	Doxx family
UA75_RS26760	COG2259	Doxx family
UA75_RS26795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
UA75_RS26810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UA75_RS26820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
UA75_RS26860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UA75_RS26865	COG1253	flavin adenine dinucleotide binding
UA75_RS26880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
UA75_RS26885	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
UA75_RS26920	COG0477	Major facilitator Superfamily
UA75_RS26935	COG1960	acyl-CoA dehydrogenase activity
UA75_RS26945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
UA75_RS26990	COG2149	membrane
UA75_RS27000	COG3629	intracellular signal transduction
UA75_RS27000	COG3903	Transcriptional regulator
UA75_RS27005	COG0596	Alpha beta hydrolase
UA75_RS27010	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
UA75_RS27010	COG2508	Transcriptional regulator
UA75_RS27015	COG0686	Belongs to the AlaDH PNT family
UA75_RS27045	COG0508	dehydrogenase complex catalyzes the overall conversion of
UA75_RS27045	COG0567	Dehydrogenase, E1 component
UA75_RS27070	COG1228	amidohydrolase
UA75_RS27095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
UA75_RS27100	COG2986	histidine ammonia-lyase
UA75_RS27135	COG1174	glycine betaine transport
UA75_RS27140	COG1174	glycine betaine transport
UA75_RS27145	COG0517	IMP dehydrogenase activity
UA75_RS27145	COG1125	glycine betaine transport
UA75_RS27175	COG0406	alpha-ribazole phosphatase activity
UA75_RS27195	COG1597	lipid kinase activity
UA75_RS27210	COG5662	AntiSigma factor
UA75_RS27220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UA75_RS27230	COG2135	peptidase activity
UA75_RS27240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
UA75_RS27260	COG1012	belongs to the aldehyde dehydrogenase family
UA75_RS27275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UA75_RS27280	COG1011	Hydrolase
UA75_RS27290	COG0653	protein targeting
UA75_RS27295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
UA75_RS27310	COG5000	phosphorelay sensor kinase activity
UA75_RS27310	COG5002	protein histidine kinase activity
UA75_RS27315	COG0745	RESPONSE REGULATOR receiver
UA75_RS27340	COG0531	amino acid
UA75_RS27345	COG1482	cell wall glycoprotein biosynthetic process
UA75_RS27355	COG2835	tetraacyldisaccharide 4'-kinase activity
UA75_RS27380	COG1994	Peptidase M50
UA75_RS27385	COG0391	Required for morphogenesis under gluconeogenic growth conditions
UA75_RS27390	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
UA75_RS27390	COG0778	Nitroreductase
UA75_RS27415	COG2188	Transcriptional regulator
UA75_RS27420	COG0641	radical SAM
UA75_RS27430	COG0297	glycogen (starch) synthase activity
UA75_RS27435	COG0438	transferase activity, transferring glycosyl groups
UA75_RS27440	COG1215	transferase activity, transferring glycosyl groups
UA75_RS27455	COG0438	transferase activity, transferring glycosyl groups
UA75_RS27470	COG1316	TRANSCRIPTIONal
UA75_RS27475	COG1316	TRANSCRIPTIONal
UA75_RS27495	COG1131	(ABC) transporter
UA75_RS27505	COG1879	ABC-type sugar transport system periplasmic component
UA75_RS27510	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS27515	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS27520	COG1129	ABC transporter
UA75_RS27535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
UA75_RS27545	COG1690	Belongs to the RtcB family
UA75_RS27580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
UA75_RS27585	COG2205	protein histidine kinase activity
UA75_RS27590	COG0745	RESPONSE REGULATOR receiver
UA75_RS27595	COG0483	inositol monophosphate 1-phosphatase activity
UA75_RS27645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
UA75_RS27660	COG3795	YCII-related domain
UA75_RS27665	COG2936	dipeptidyl-peptidase activity
UA75_RS27670	COG3311	Transcriptional regulator
UA75_RS27675	COG1840	ABC-type Fe3 transport system, periplasmic component
UA75_RS27685	COG3842	ATPase activity
UA75_RS27690	COG2828	Protein conserved in bacteria
UA75_RS27695	COG0583	DNA-binding transcription factor activity
UA75_RS27700	COG0424	maF-like protein
UA75_RS27710	COG1301	dicarboxylic acid transport
UA75_RS27715	COG4770	biotin carboxylase activity
UA75_RS27745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UA75_RS27750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UA75_RS27755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
UA75_RS27790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
UA75_RS27790	COG1473	amidohydrolase
UA75_RS27840	COG0109	protoheme IX farnesyltransferase activity
UA75_RS27870	COG1172	Belongs to the binding-protein-dependent transport system permease family
UA75_RS27875	COG1129	ABC transporter
UA75_RS27890	COG0702	epimerase
UA75_RS27905	COG4585	Histidine kinase
UA75_RS27910	COG1131	(ABC) transporter
UA75_RS27920	COG1940	carbohydrate kinase activity
UA75_RS27925	COG1070	Carbohydrate kinase
UA75_RS27930	COG3226	Transcriptional regulator
UA75_RS27960	COG0651	ATP synthesis coupled electron transport
UA75_RS27965	COG1006	Multisubunit Na H antiporter MnhC subunit
UA75_RS27975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
UA75_RS27975	COG2111	Na H antiporter
UA75_RS27980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
UA75_RS27980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
UA75_RS27985	COG0515	serine threonine protein kinase
UA75_RS27995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UA75_RS28000	COG0667	Aldo Keto reductase
UA75_RS28010	COG3654	unkown
UA75_RS28045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UA75_RS28115	COG1012	belongs to the aldehyde dehydrogenase family
UA75_RS28120	COG1012	belongs to the aldehyde dehydrogenase family
UA75_RS28170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
UA75_RS28190	COG1079	Belongs to the binding-protein-dependent transport system permease family
UA75_RS28200	COG3845	ABC transporter
UA75_RS28205	COG1744	ABC transporter substrate-binding protein PnrA-like
UA75_RS28210	COG2009	succinate dehydrogenase
UA75_RS28225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UA75_RS28230	COG1686	Belongs to the peptidase S11 family
UA75_RS28235	COG1295	ribonuclease BN
UA75_RS28255	COG0708	Exodeoxyribonuclease III
UA75_RS28300	COG0039	L-malate dehydrogenase activity
UA75_RS28315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UA75_RS28350	COG0587	DNA-directed DNA polymerase activity
UA75_RS28365	COG0138	bifunctional purine biosynthesis protein purh
UA75_RS28390	COG0045	succinate-CoA ligase (ADP-forming) activity
UA75_RS28400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
UA75_RS28410	COG0739	heme binding
UA75_RS28415	COG4942	peptidase
UA75_RS28425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS28505	COG0515	serine threonine protein kinase
UA75_RS28515	COG0583	DNA-binding transcription factor activity
UA75_RS28550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UA75_RS28550	COG0519	Catalyzes the synthesis of GMP from XMP
UA75_RS28555	COG1012	belongs to the aldehyde dehydrogenase family
UA75_RS28590	COG0516	GMP reductase activity
UA75_RS28630	COG0459	protein refolding
UA75_RS28635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
UA75_RS28640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS28645	COG3540	Alkaline phosphatase
UA75_RS28650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
UA75_RS28655	COG0456	acetyltransferase
UA75_RS28665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
UA75_RS28670	COG1414	Transcriptional regulator
UA75_RS28680	COG0802	atpase or kinase
UA75_RS28690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
UA75_RS28700	COG0736	holo-[acyl-carrier-protein] synthase activity
UA75_RS28740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UA75_RS28745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UA75_RS28750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UA75_RS28765	COG0443	Heat shock 70 kDa protein
UA75_RS28770	COG1674	ftsk spoiiie
UA75_RS28780	COG1404	Belongs to the peptidase S8 family
UA75_RS28835	COG3300	MHYT domain
UA75_RS28835	COG5001	Diguanylate cyclase
UA75_RS28850	COG4122	O-methyltransferase activity
UA75_RS28880	COG1674	ftsk spoiiie
UA75_RS28890	COG0456	acetyltransferase
UA75_RS28895	COG2130	NADP-dependent
UA75_RS28915	COG4152	abc transporter atp-binding protein
UA75_RS28920	COG1668	transmembrane transport
UA75_RS28925	COG0415	Belongs to the DNA photolyase family
UA75_RS28940	COG1228	amidohydrolase
UA75_RS28945	COG2017	converts alpha-aldose to the beta-anomer
UA75_RS28950	COG0531	amino acid
UA75_RS28955	COG0477	Major facilitator Superfamily
UA75_RS28960	COG0259	pyridoxamine-phosphate oxidase activity
UA75_RS28995	COG1132	(ABC) transporter
UA75_RS29025	COG2252	PERMEase
UA75_RS29050	COG2814	Major facilitator Superfamily
UA75_RS29070	COG1278	Cold shock
UA75_RS29080	COG0546	phosphoglycolate phosphatase activity
UA75_RS29105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UA75_RS29115	COG1652	LysM domain
UA75_RS29125	COG0315	cyclic pyranopterin monophosphate synthase activity
UA75_RS29160	COG2018	Roadblock/LC7 domain
UA75_RS29185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UA75_RS29190	COG1116	anion transmembrane transporter activity
UA75_RS29195	COG1061	Type III restriction enzyme res subunit
UA75_RS29220	COG3142	Participates in the control of copper homeostasis
UA75_RS29245	COG0459	protein refolding
UA75_RS29270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UA75_RS29275	COG0167	dihydroorotate dehydrogenase activity
UA75_RS29305	COG1136	(ABC) transporter
UA75_RS29325	COG2733	membrane
UA75_RS29405	COG1733	regulation of RNA biosynthetic process
UA75_RS29420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UA75_RS29430	COG0519	Catalyzes the synthesis of GMP from XMP
UA75_RS29450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UA75_RS29455	COG2364	Membrane
UA75_RS29465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
UA75_RS29470	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
UA75_RS29490	COG1215	transferase activity, transferring glycosyl groups
UA75_RS29525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UA75_RS29545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UA75_RS29580	COG1316	TRANSCRIPTIONal
UA75_RS29590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
UA75_RS29595	COG1960	acyl-CoA dehydrogenase activity
UA75_RS29610	COG3844	kynureninase activity
UA75_RS29700	COG0531	amino acid
UA75_RS29700	COG1674	ftsk spoiiie
UA75_RS29785	COG0704	Plays a role in the regulation of phosphate uptake
UA75_RS29795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UA75_RS29800	COG0581	inorganic phosphate transmembrane transporter activity
UA75_RS29815	COG0456	acetyltransferase
UA75_RS29820	COG0745	RESPONSE REGULATOR receiver
UA75_RS29855	COG4044	May play a role in the intracellular transport of hydrophobic ligands
UA75_RS29920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
UA75_RS29935	COG3387	PFAM Glycoside hydrolase 15-related
UA75_RS29960	COG0047	phosphoribosylformylglycinamidine synthase activity
UA75_RS29965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
UA75_RS29995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
UA75_RS30005	COG1595	DNA-templated transcription, initiation
UA75_RS30010	COG0789	Transcriptional regulator
UA75_RS30035	COG1595	DNA-templated transcription, initiation
UA75_RS30045	COG1011	Hydrolase
UA75_RS30055	COG0436	Aminotransferase
UA75_RS30070	COG0025	NhaP-type Na H and K H
UA75_RS30075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
UA75_RS30135	COG1309	transcriptional regulator
UA75_RS30140	COG2814	Major facilitator Superfamily
UA75_RS30155	COG4129	membrane
UA75_RS30195	COG1940	carbohydrate kinase activity
UA75_RS30210	COG0277	FAD linked oxidase domain protein
UA75_RS30220	COG2197	response regulator
UA75_RS30230	COG1136	(ABC) transporter
UA75_RS30245	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
UA75_RS30250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
UA75_RS30255	COG0443	Heat shock 70 kDa protein
UA75_RS30300	COG1115	amino acid carrier protein
UA75_RS30305	COG0471	metal ion transport
UA75_RS30310	COG0542	response to heat
UA75_RS30320	COG4221	oxidoreductase activity
UA75_RS30330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
UA75_RS30370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UA75_RS30375	COG1704	LemA family
UA75_RS30380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UA75_RS30395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
UA75_RS30405	COG0789	Transcriptional regulator
UA75_RS30415	COG0484	heat shock protein binding
UA75_RS30420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UA75_RS30425	COG0443	Heat shock 70 kDa protein
UA75_RS30435	COG0247	lactate metabolic process
UA75_RS30435	COG2181	nitrate reductase activity
UA75_RS30440	COG1120	ATPase activity
UA75_RS30445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UA75_RS30460	COG5398	heme oxygenase
UA75_RS30470	COG1028	Short-chain dehydrogenase reductase Sdr
UA75_RS30500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UA75_RS30510	COG0477	Major facilitator Superfamily
UA75_RS30525	COG1960	acyl-CoA dehydrogenase activity
UA75_RS30545	COG2375	cellular response to nickel ion
UA75_RS30545	COG1132	(ABC) transporter
UA75_RS30555	COG1309	transcriptional regulator
UA75_RS30565	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
UA75_RS30595	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
UA75_RS30605	COG1126	abc transporter atp-binding protein
UA75_RS30610	COG0765	amino acid transport
UA75_RS30615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UA75_RS30620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UA75_RS30635	COG0022	dehydrogenase e1 component
UA75_RS30640	COG0508	dehydrogenase complex catalyzes the overall conversion of
UA75_RS30650	COG4221	oxidoreductase activity
UA75_RS30670	COG3339	Conserved Protein
UA75_RS30690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UA75_RS30705	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
UA75_RS30710	COG0360	Binds together with S18 to 16S ribosomal RNA
UA75_RS30715	COG0629	single-stranded DNA binding
UA75_RS30720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UA75_RS30725	COG0359	binds to the 23S rRNA
UA75_RS30730	COG0305	Participates in initiation and elongation during chromosome replication
UA75_RS30755	COG2124	cytochrome p450
UA75_RS30760	COG0789	Transcriptional regulator
UA75_RS30770	COG0789	Transcriptional regulator
UA75_RS30780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UA75_RS30785	COG2814	Major facilitator Superfamily
UA75_RS30840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UA75_RS30845	COG1869	D-ribose catabolic process
UA75_RS30850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UA75_RS30860	COG1129	ABC transporter
UA75_RS30890	COG0495	leucyl-tRNA aminoacylation
UA75_RS30900	COG1678	Uncharacterized ACR, COG1678
UA75_RS30910	COG0617	tRNA 3'-terminal CCA addition
UA75_RS30930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UA75_RS30930	COG0515	serine threonine protein kinase
UA75_RS30935	COG1595	DNA-templated transcription, initiation
UA75_RS30955	COG0860	N-Acetylmuramoyl-L-alanine amidase
UA75_RS30955	COG3409	Peptidoglycan-binding domain 1 protein
UA75_RS30965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UA75_RS30975	COG1475	DNA binding
UA75_RS30980	COG1192	Involved in chromosome partitioning
UA75_RS30985	COG0357	Ribosomal RNA small subunit methyltransferase G
UA75_RS31005	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
UA75_RS31010	COG0594	ribonuclease P activity
UA75_RS31015	COG0230	Belongs to the bacterial ribosomal protein bL34 family
UA75_RS31020	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UA75_RS31055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UA75_RS31075	COG0187	DNA topoisomerase II activity
UA75_RS31080	COG0187	DNA topoisomerase II activity
UA75_RS31085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UA75_RS31090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner