locus-tag	class	description
J3K87_RS00010	COG0592	DNA-directed DNA polymerase activity
J3K87_RS00025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J3K87_RS00040	COG0616	signal peptide processing
J3K87_RS00055	COG3116	cell division
J3K87_RS00060	COG0768	penicillin binding
J3K87_RS00065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J3K87_RS00070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J3K87_RS00080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J3K87_RS00085	COG0772	Belongs to the SEDS family
J3K87_RS00090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J3K87_RS00095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J3K87_RS00100	COG1181	Belongs to the D-alanine--D-alanine ligase family
J3K87_RS00110	COG0849	cell division
J3K87_RS00115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J3K87_RS00120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J3K87_RS00125	COG0497	DNA recombination
J3K87_RS00130	COG4172	Belongs to the ABC transporter superfamily
J3K87_RS00135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J3K87_RS00140	COG0601	transmembrane transport
J3K87_RS00170	COG0012	GTP binding
J3K87_RS00175	COG2020	methyltransferase activity
J3K87_RS00185	COG3133	Outer membrane lipoprotein
J3K87_RS00190	COG3102	Protein conserved in bacteria
J3K87_RS00195	COG0018	arginyl-trna synthetase
J3K87_RS00210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J3K87_RS00215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J3K87_RS00220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J3K87_RS00225	COG0196	riboflavin kinase activity
J3K87_RS00230	COG3172	ATPase kinase involved in NAD metabolism
J3K87_RS00235	COG2129	metallophosphoesterase
J3K87_RS00240	COG0745	RESPONSE REGULATOR receiver
J3K87_RS00250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J3K87_RS00255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J3K87_RS00260	COG1217	gtp-binding protein TYPA
J3K87_RS00265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J3K87_RS00270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J3K87_RS00275	COG1561	YicC-like family, N-terminal region
J3K87_RS00280	COG0354	folic acid binding
J3K87_RS00285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J3K87_RS00290	COG2197	response regulator
J3K87_RS00300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J3K87_RS00340	COG0747	negative chemotaxis
J3K87_RS00345	COG0601	transmembrane transport
J3K87_RS00350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J3K87_RS00355	COG0444	Belongs to the ABC transporter superfamily
J3K87_RS00360	COG4608	Belongs to the ABC transporter superfamily
J3K87_RS00375	COG0251	oxidation-reduction process
J3K87_RS00380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J3K87_RS00385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J3K87_RS00390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J3K87_RS00395	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J3K87_RS00400	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J3K87_RS00405	COG0848	biopolymer transport protein
J3K87_RS00410	COG0811	peptide transport
J3K87_RS00415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J3K87_RS00420	COG3118	belongs to the thioredoxin family
J3K87_RS00425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J3K87_RS00425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_RS00425	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
J3K87_RS00430	COG1461	Dihydroxyacetone kinase
J3K87_RS00435	COG2376	Dihydroxyacetone kinase
J3K87_RS00440	COG0492	ferredoxin-NADP+ reductase activity
J3K87_RS00450	COG3753	Protein conserved in bacteria
J3K87_RS00470	COG3030	protein affecting phage T7 exclusion by the F plasmid
J3K87_RS00475	COG0006	proline dipeptidase activity
J3K87_RS00485	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
J3K87_RS00505	COG0129	dihydroxy-acid dehydratase activity
J3K87_RS00510	COG3978	acetolactate synthase activity
J3K87_RS00525	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J3K87_RS00530	COG0437	4 iron, 4 sulfur cluster binding
J3K87_RS00535	COG3301	Polysulphide reductase, NrfD
J3K87_RS00550	COG5295	Hep Hag repeat protein
J3K87_RS00550	COG5295	Hep Hag repeat protein
J3K87_RS00565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3K87_RS00570	COG1414	Transcriptional regulator
J3K87_RS00575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J3K87_RS00600	COG3068	Protein conserved in bacteria
J3K87_RS00625	COG1278	Cold shock
J3K87_RS00630	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J3K87_RS00635	COG0793	Belongs to the peptidase S41A family
J3K87_RS00640	COG2989	Protein conserved in bacteria
J3K87_RS00645	COG3108	Peptidase M15
J3K87_RS00650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3K87_RS00665	COG0537	adenosine 5'-monophosphoramidase activity
J3K87_RS00670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J3K87_RS00675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J3K87_RS00685	COG1162	GTPase activity
J3K87_RS00690	COG0583	DNA-binding transcription factor activity
J3K87_RS00695	COG1011	Hydrolase
J3K87_RS00700	COG0583	DNA-binding transcription factor activity
J3K87_RS00710	COG0252	asparaginase activity
J3K87_RS00720	COG5413	integral membrane protein
J3K87_RS00735	COG3835	regulator
J3K87_RS00740	COG2610	gluconate transmembrane transporter activity
J3K87_RS00745	COG1929	Belongs to the glycerate kinase type-1 family
J3K87_RS00750	COG1254	Belongs to the acylphosphatase family
J3K87_RS00755	COG3593	DNA synthesis involved in DNA repair
J3K87_RS00760	COG1611	Belongs to the LOG family
J3K87_RS00765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J3K87_RS00775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J3K87_RS00780	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J3K87_RS00780	COG0316	Belongs to the HesB IscA family
J3K87_RS00785	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_RS00790	COG1805	sodium ion transport
J3K87_RS00795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_RS00800	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_RS00805	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3K87_RS00810	COG2871	sodium ion transport
J3K87_RS00815	COG1477	protein flavinylation
J3K87_RS00820	COG2991	Protein conserved in bacteria
J3K87_RS00825	COG0482	sulfurtransferase activity
J3K87_RS00830	COG2814	Major facilitator Superfamily
J3K87_RS00835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J3K87_RS00840	COG2974	May be involved in recombination
J3K87_RS00845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J3K87_RS00865	COG4657	Part of a membrane complex involved in electron transport
J3K87_RS00870	COG2878	Part of a membrane complex involved in electron transport
J3K87_RS00875	COG4656	Part of a membrane complex involved in electron transport
J3K87_RS00900	COG1560	Kdo2-lipid A biosynthetic process
J3K87_RS00905	COG0402	S-adenosylhomocysteine deaminase activity
J3K87_RS00910	COG4143	(ABC) transporter
J3K87_RS00915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J3K87_RS00920	COG0617	tRNA 3'-terminal CCA addition
J3K87_RS00925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J3K87_RS00935	COG2911	Protein conserved in bacteria
J3K87_RS00945	COG0346	lactoylglutathione lyase activity
J3K87_RS00950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J3K87_RS00960	COG0287	Prephenate dehydrogenase
J3K87_RS00960	COG1605	Chorismate mutase
J3K87_RS00965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J3K87_RS00970	COG0859	PFAM glycosyl transferase family 9
J3K87_RS00975	COG0469	pyruvate kinase activity
J3K87_RS00980	COG2062	phosphohistidine phosphatase, SixA
J3K87_RS00985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J3K87_RS00990	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J3K87_RS00995	COG0733	neurotransmitter:sodium symporter activity
J3K87_RS01000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J3K87_RS01005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J3K87_RS01010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J3K87_RS01015	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J3K87_RS01020	COG4972	Pilus assembly protein
J3K87_RS01040	COG4796	Type ii and iii secretion system protein
J3K87_RS01045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J3K87_RS01050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J3K87_RS01055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J3K87_RS01060	COG1280	lysine exporter protein (LysE YggA)
J3K87_RS01065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J3K87_RS01075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J3K87_RS01090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J3K87_RS01145	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J3K87_RS01150	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J3K87_RS01155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J3K87_RS01175	COG1253	flavin adenine dinucleotide binding
J3K87_RS01180	COG0564	pseudouridine synthase activity
J3K87_RS01185	COG0406	alpha-ribazole phosphatase activity
J3K87_RS01190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J3K87_RS01195	COG1678	Uncharacterized ACR, COG1678
J3K87_RS01200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J3K87_RS01210	COG0271	Belongs to the BolA IbaG family
J3K87_RS01235	COG0653	protein targeting
J3K87_RS01250	COG0494	nUDIX hydrolase
J3K87_RS01255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J3K87_RS01265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J3K87_RS01275	COG1629	transport
J3K87_RS01275	COG4771	TonB-dependent receptor
J3K87_RS01285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J3K87_RS01290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J3K87_RS01295	COG0083	homoserine kinase activity
J3K87_RS01300	COG0460	homoserine dehydrogenase
J3K87_RS01300	COG0527	aspartate kinase activity
J3K87_RS01305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J3K87_RS01310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J3K87_RS01315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J3K87_RS01345	COG2195	Cleaves the N-terminal amino acid of tripeptides
J3K87_RS01350	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J3K87_RS01355	COG0194	GDP metabolic process
J3K87_RS01360	COG1538	Outer membrane efflux protein
J3K87_RS01365	COG2914	Belongs to the UPF0125 (RnfH) family
J3K87_RS01370	COG2867	negative regulation of translational initiation
J3K87_RS01375	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J3K87_RS01380	COG4149	molybdate abc transporter
J3K87_RS01385	COG0725	ABC transporter, periplasmic molybdate-binding protein
J3K87_RS01390	COG0842	Transport permease protein
J3K87_RS01395	COG1131	(ABC) transporter
J3K87_RS01400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J3K87_RS01405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J3K87_RS01420	COG0251	oxidation-reduction process
J3K87_RS01425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J3K87_RS01430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J3K87_RS01435	COG1121	(ABC) transporter
J3K87_RS01445	COG2920	part of a sulfur-relay system
J3K87_RS01450	COG0670	Belongs to the BI1 family
J3K87_RS01455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J3K87_RS01470	COG0084	hydrolase, TatD family'
J3K87_RS01475	COG0210	DNA helicase
J3K87_RS01480	COG3842	ATPase activity
J3K87_RS01485	COG1176	ABC-type spermidine putrescine transport system, permease component I
J3K87_RS01490	COG1177	transmembrane transport
J3K87_RS01495	COG0632	four-way junction helicase activity
J3K87_RS01500	COG2255	four-way junction helicase activity
J3K87_RS01505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J3K87_RS01510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J3K87_RS01545	COG0488	(ABC) transporter
J3K87_RS01550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J3K87_RS01560	COG1271	oxidase subunit
J3K87_RS01565	COG1294	oxidase, subunit
J3K87_RS01580	COG0824	Thioesterase
J3K87_RS01585	COG0811	peptide transport
J3K87_RS01590	COG0848	biopolymer transport protein
J3K87_RS01595	COG3064	Membrane
J3K87_RS01595	COG3064	Membrane
J3K87_RS01600	COG0823	Involved in the tonB-independent uptake of proteins
J3K87_RS01615	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J3K87_RS01620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J3K87_RS01630	COG0488	(ABC) transporter
J3K87_RS01640	COG0303	'Molybdopterin
J3K87_RS01645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J3K87_RS01655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J3K87_RS01660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J3K87_RS01670	COG0564	pseudouridine synthase activity
J3K87_RS01675	COG3023	N-Acetylmuramoyl-L-alanine amidase
J3K87_RS01680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J3K87_RS01685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J3K87_RS01690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J3K87_RS01695	COG0626	cystathionine gamma-synthase activity
J3K87_RS01700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J3K87_RS01715	COG1702	phosphate starvation-inducible protein PhoH
J3K87_RS01740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J3K87_RS01760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J3K87_RS01765	COG1660	Displays ATPase and GTPase activities
J3K87_RS01770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_RS01775	COG1137	ATPase activity
J3K87_RS01780	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J3K87_RS01790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J3K87_RS01795	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J3K87_RS01805	COG1704	LemA family
J3K87_RS01810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J3K87_RS01810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J3K87_RS01810	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J3K87_RS01815	COG1105	Belongs to the carbohydrate kinase PfkB family
J3K87_RS01820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_RS01820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_RS01830	COG1523	belongs to the glycosyl hydrolase 13 family
J3K87_RS01835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J3K87_RS01840	COG0297	glycogen (starch) synthase activity
J3K87_RS01845	COG0058	SHG alpha-glucan phosphorylase activity
J3K87_RS01875	COG1187	pseudouridine synthase activity
J3K87_RS01880	COG2814	Major facilitator Superfamily
J3K87_RS01890	COG3381	protein complex oligomerization
J3K87_RS01900	COG0791	NLP P60 protein
J3K87_RS01905	COG2932	Transcriptional regulator
J3K87_RS01910	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J3K87_RS01915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J3K87_RS01920	COG2990	Protein conserved in bacteria
J3K87_RS01930	COG1643	Atp-dependent helicase
J3K87_RS01935	COG2707	UPF0756 membrane protein
J3K87_RS01940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J3K87_RS01945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J3K87_RS01950	COG0534	Mate efflux family protein
J3K87_RS01955	COG1074	ATP-dependent DNA helicase activity
J3K87_RS01960	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J3K87_RS01965	COG4535	Mg2 and Co2 transporter CorC
J3K87_RS01975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J3K87_RS01980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J3K87_RS01985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J3K87_RS01990	COG2271	Major facilitator Superfamily
J3K87_RS01995	COG0584	glycerophosphoryl diester phosphodiesterase
J3K87_RS02000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J3K87_RS02005	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
J3K87_RS02010	COG0247	lactate metabolic process
J3K87_RS02040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J3K87_RS02040	COG0517	IMP dehydrogenase activity
J3K87_RS02050	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
J3K87_RS02055	COG0385	Bile acid
J3K87_RS02060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_RS02065	COG0561	phosphatase activity
J3K87_RS02075	COG1595	DNA-templated transcription, initiation
J3K87_RS02080	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
J3K87_RS02090	COG0318	PFAM AMP-dependent synthetase and ligase
J3K87_RS02095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J3K87_RS02105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J3K87_RS02110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J3K87_RS02115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J3K87_RS02115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J3K87_RS02130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J3K87_RS02140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3K87_RS02145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J3K87_RS02150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3K87_RS02165	COG0750	zinc metalloprotease
J3K87_RS02170	COG0575	Belongs to the CDS family
J3K87_RS02175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J3K87_RS02180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3K87_RS02190	COG0671	phosphoesterase, PA-phosphatase related
J3K87_RS02195	COG1534	Rna-binding protein
J3K87_RS02200	COG0463	Glycosyl transferase, family 2
J3K87_RS02205	COG1686	Belongs to the peptidase S11 family
J3K87_RS02210	COG0859	PFAM glycosyl transferase family 9
J3K87_RS02220	COG0328	RNA-DNA hybrid ribonuclease activity
J3K87_RS02225	COG1286	toxin biosynthetic process
J3K87_RS02230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J3K87_RS02240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J3K87_RS02245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J3K87_RS02255	COG0251	oxidation-reduction process
J3K87_RS02260	COG1496	oxidoreductase activity
J3K87_RS02270	COG0582	viral genome integration into host DNA
J3K87_RS02390	COG0582	viral genome integration into host DNA
J3K87_RS02445	COG0556	nucleotide-excision repair
J3K87_RS02460	COG3179	chitinase
J3K87_RS02475	COG3728	DNA packaging
J3K87_RS02600	COG5645	(Lipo)protein
J3K87_RS02615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J3K87_RS02625	COG1792	Involved in formation and maintenance of cell shape
J3K87_RS02630	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J3K87_RS02635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J3K87_RS02640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J3K87_RS02645	COG0121	glutamine amidotransferase
J3K87_RS02650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J3K87_RS02655	COG2949	membrane
J3K87_RS02665	COG1556	Lactate utilization protein
J3K87_RS02670	COG1139	Iron-sulfur cluster binding protein
J3K87_RS02675	COG0247	lactate metabolic process
J3K87_RS02680	COG1620	l-lactate permease
J3K87_RS02685	COG2916	Histone family protein nucleoid-structuring protein H-NS
J3K87_RS02690	COG1757	Na H antiporter
J3K87_RS02695	COG1879	ABC-type sugar transport system periplasmic component
J3K87_RS02700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J3K87_RS02710	COG2990	Protein conserved in bacteria
J3K87_RS02715	COG0508	dehydrogenase complex catalyzes the overall conversion of
J3K87_RS02720	COG0567	Dehydrogenase, E1 component
J3K87_RS02725	COG1121	(ABC) transporter
J3K87_RS02730	COG0739	heme binding
J3K87_RS02735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J3K87_RS02740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J3K87_RS02750	COG0561	phosphatase activity
J3K87_RS02755	COG3850	Histidine kinase
J3K87_RS02765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J3K87_RS02775	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J3K87_RS02785	COG4221	oxidoreductase activity
J3K87_RS02790	COG0133	tryptophan synthase activity
J3K87_RS02795	COG0159	tryptophan synthase activity
J3K87_RS02810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J3K87_RS02810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J3K87_RS02825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J3K87_RS02830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J3K87_RS02855	COG0640	Transcriptional regulator
J3K87_RS02865	COG0189	ligase activity
J3K87_RS02870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J3K87_RS02875	COG0281	malic enzyme
J3K87_RS02875	COG0280	phosphate acetyltransferase
J3K87_RS02890	COG3683	transport system, periplasmic component
J3K87_RS02895	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
J3K87_RS02900	COG1115	amino acid carrier protein
J3K87_RS02905	COG1116	anion transmembrane transporter activity
J3K87_RS02910	COG1116	anion transmembrane transporter activity
J3K87_RS02915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J3K87_RS02920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J3K87_RS02925	COG2104	thiamine diphosphate biosynthetic process
J3K87_RS02930	COG2022	thiamine diphosphate biosynthetic process
J3K87_RS02935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J3K87_RS02940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J3K87_RS02950	COG0351	phosphomethylpyrimidine kinase
J3K87_RS02960	COG0481	GTPase activity
J3K87_RS02965	COG0681	Belongs to the peptidase S26 family
J3K87_RS02975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J3K87_RS02990	COG2826	transposase and inactivated derivatives, IS30 family
J3K87_RS02995	COG1840	ABC-type Fe3 transport system, periplasmic component
J3K87_RS03015	COG4178	(ABC) transporter
J3K87_RS03030	COG2194	sulfuric ester hydrolase activity
J3K87_RS03035	COG0528	UMP kinase activity
J3K87_RS03040	COG0233	cytoplasmic translational termination
J3K87_RS03045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J3K87_RS03050	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
J3K87_RS03055	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J3K87_RS03060	COG0590	tRNA wobble adenosine to inosine editing
J3K87_RS03065	COG0513	Belongs to the DEAD box helicase family
J3K87_RS03070	COG4785	May be involved in cell division
J3K87_RS03075	COG1185	polyribonucleotide nucleotidyltransferase activity
J3K87_RS03080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J3K87_RS03090	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J3K87_RS03105	COG3083	sulfuric ester hydrolase activity
J3K87_RS03115	COG1309	transcriptional regulator
J3K87_RS03120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_RS03125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3K87_RS03140	COG3955	Domain of unknown function (DUF1919)
J3K87_RS03145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J3K87_RS03160	COG0516	GMP reductase activity
J3K87_RS03160	COG0517	IMP dehydrogenase activity
J3K87_RS03165	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J3K87_RS03170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J3K87_RS03175	COG0814	amino acid
J3K87_RS03180	COG0814	amino acid
J3K87_RS03190	COG3105	Protein conserved in bacteria
J3K87_RS03195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J3K87_RS03220	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J3K87_RS03225	COG1823	symporter activity
J3K87_RS03230	COG0778	Nitroreductase
J3K87_RS03240	COG0072	phenylalanine-tRNA ligase activity
J3K87_RS03245	COG0776	regulation of translation
J3K87_RS03250	COG0791	NLP P60 protein
J3K87_RS03260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J3K87_RS03265	COG1940	carbohydrate kinase activity
J3K87_RS03265	COG1846	Transcriptional regulator
J3K87_RS03270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J3K87_RS03275	COG1522	sequence-specific DNA binding
J3K87_RS03280	COG1674	ftsk spoiiie
J3K87_RS03285	COG2321	neutral zinc metallopeptidase
J3K87_RS03290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J3K87_RS03295	COG1214	PFAM Peptidase M22, glycoprotease
J3K87_RS03300	COG1435	thymidine kinase activity
J3K87_RS03305	COG3074	FtsZ-dependent cytokinesis
J3K87_RS03310	COG1494	fructose-1,6-bisphosphatase
J3K87_RS03315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J3K87_RS03320	COG0577	efflux transmembrane transporter activity
J3K87_RS03320	COG1136	(ABC) transporter
J3K87_RS03325	COG2205	protein histidine kinase activity
J3K87_RS03330	COG0745	RESPONSE REGULATOR receiver
J3K87_RS03335	COG3956	TIGRFAM MazG family protein
J3K87_RS03345	COG0285	dihydrofolate synthase activity
J3K87_RS03355	COG0779	Required for maturation of 30S ribosomal subunits
J3K87_RS03360	COG0195	Participates in both transcription termination and antitermination
J3K87_RS03365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J3K87_RS03370	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J3K87_RS03375	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J3K87_RS03380	COG2951	lytic endotransglycosylase activity
J3K87_RS03390	COG0857	belongs to the CobB CobQ family
J3K87_RS03390	COG0280	phosphate acetyltransferase
J3K87_RS03400	COG0737	Belongs to the 5'-nucleotidase family
J3K87_RS03420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J3K87_RS03430	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J3K87_RS03440	COG0589	response to stress
J3K87_RS03450	COG2969	positive regulation of protein catabolic process
J3K87_RS03455	COG0625	glutathione transferase activity
J3K87_RS03460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J3K87_RS03470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J3K87_RS03475	COG1448	Aminotransferase
J3K87_RS03480	COG0006	proline dipeptidase activity
J3K87_RS03510	COG1487	ribonuclease activity
J3K87_RS03525	COG0556	nucleotide-excision repair
J3K87_RS03530	COG2822	iron ion transport
J3K87_RS03535	COG2837	iron assimilation
J3K87_RS03545	COG0613	PHP domain protein
J3K87_RS03555	COG2925	Exonuclease
J3K87_RS03560	COG0038	chloride channel
J3K87_RS03570	COG1509	lysine 2,3-aminomutase activity
J3K87_RS03580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J3K87_RS03585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J3K87_RS03595	COG2814	Major facilitator Superfamily
J3K87_RS03600	COG0741	lytic transglycosylase activity
J3K87_RS03605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J3K87_RS03610	COG0626	cystathionine gamma-synthase activity
J3K87_RS03635	COG2363	Small membrane protein
J3K87_RS03640	COG0277	FAD linked oxidase domain protein
J3K87_RS03645	COG0243	molybdopterin cofactor binding
J3K87_RS03650	COG3005	denitrification pathway
J3K87_RS03660	COG0315	cyclic pyranopterin monophosphate synthase activity
J3K87_RS03665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J3K87_RS03670	COG0314	molybdopterin synthase activity
J3K87_RS03675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J3K87_RS03680	COG1444	tRNA N-acetyltransferase activity
J3K87_RS03690	COG0583	DNA-binding transcription factor activity
J3K87_RS03715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J3K87_RS03720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J3K87_RS03735	COG1737	Transcriptional regulator
J3K87_RS03740	COG2731	YhcH YjgK YiaL family protein
J3K87_RS03745	COG0248	Ppx GppA phosphatase
J3K87_RS03750	COG2926	Belongs to the UPF0265 family
J3K87_RS03755	COG0527	aspartate kinase activity
J3K87_RS03760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J3K87_RS03765	COG3100	YcgL domain-containing protein
J3K87_RS03770	COG0305	Participates in initiation and elongation during chromosome replication
J3K87_RS03775	COG4607	ABC-type enterochelin transport system periplasmic component
J3K87_RS03780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J3K87_RS03785	COG4605	iron ion homeostasis
J3K87_RS03790	COG4604	ABC transporter, ATP-binding protein
J3K87_RS03795	COG1392	Phosphate transport regulator
J3K87_RS03800	COG0306	phosphate transporter
J3K87_RS03805	COG4991	sh3 domain protein
J3K87_RS03815	COG3945	hemerythrin HHE cation binding domain
J3K87_RS03830	COG1278	Cold shock
J3K87_RS03835	COG0288	reversible hydration of carbon dioxide
J3K87_RS03840	COG0028	Belongs to the TPP enzyme family
J3K87_RS03845	COG0440	acetolactate synthase activity
J3K87_RS03850	COG0312	modulator of DNA gyrase
J3K87_RS03855	COG3028	Belongs to the UPF0307 family
J3K87_RS03860	COG3094	Invasion gene expression up-regulator, SirB
J3K87_RS03870	COG1811	Na channel or pump
J3K87_RS03875	COG3787	Belongs to the UPF0306 family
J3K87_RS03880	COG0023	Translation Initiation Factor
J3K87_RS03885	COG0284	orotidine-5'-phosphate decarboxylase activity
J3K87_RS03890	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J3K87_RS03895	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J3K87_RS03900	COG0776	regulation of translation
J3K87_RS03905	COG0539	negative regulation of cytoplasmic translation
J3K87_RS03915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3K87_RS03925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J3K87_RS03935	COG1785	Belongs to the alkaline phosphatase family
J3K87_RS03940	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
J3K87_RS03950	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J3K87_RS03950	COG3264	Mechanosensitive ion channel
J3K87_RS03955	COG3264	Mechanosensitive ion channel
J3K87_RS03955	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J3K87_RS03960	COG0318	PFAM AMP-dependent synthetase and ligase
J3K87_RS03965	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J3K87_RS03970	COG0596	Alpha beta hydrolase
J3K87_RS03980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J3K87_RS04000	COG1380	Effector of murein hydrolase LrgA
J3K87_RS04005	COG1346	cytolysis
J3K87_RS04020	COG3036	rescue of stalled ribosome
J3K87_RS04025	COG2226	methyltransferase
J3K87_RS04045	COG2333	competence protein COMEC
J3K87_RS04045	COG0658	competence protein
J3K87_RS04050	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J3K87_RS04055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J3K87_RS04060	COG0737	Belongs to the 5'-nucleotidase family
J3K87_RS04085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J3K87_RS04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
J3K87_RS04095	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J3K87_RS04105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J3K87_RS04120	COG1132	(ABC) transporter
J3K87_RS04125	COG1346	cytolysis
J3K87_RS04135	COG1199	ATP-dependent helicase activity
J3K87_RS04145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J3K87_RS04150	COG0629	single-stranded DNA binding
J3K87_RS04190	COG2070	2-Nitropropane dioxygenase
J3K87_RS04205	COG2814	Major facilitator Superfamily
J3K87_RS04210	COG2315	Protein conserved in bacteria
J3K87_RS04215	COG4172	Belongs to the ABC transporter superfamily
J3K87_RS04220	COG4171	peptide transport system, permease
J3K87_RS04225	COG4168	peptide transport system, permease
J3K87_RS04230	COG4166	transmembrane transport
J3K87_RS04235	COG3283	Transcriptional regulator of aromatic amino acids metabolism
J3K87_RS04240	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J3K87_RS04245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J3K87_RS04250	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J3K87_RS04260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J3K87_RS04270	COG1368	sulfuric ester hydrolase activity
J3K87_RS04275	COG3217	Mosc domain protein beta barrel domain protein
J3K87_RS04275	COG0633	Ferredoxin
J3K87_RS04280	COG1722	exodeoxyribonuclease VII activity
J3K87_RS04285	COG0142	geranyltranstransferase activity
J3K87_RS04295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J3K87_RS04300	COG1530	ribonuclease E activity
J3K87_RS04305	COG1944	ATP diphosphatase activity
J3K87_RS04320	COG0500	methyltransferase
J3K87_RS04330	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J3K87_RS04385	COG2826	transposase and inactivated derivatives, IS30 family
J3K87_RS04450	COG4104	PAAR repeat-containing protein
J3K87_RS04450	COG3209	COG3209 Rhs family protein
J3K87_RS04455	COG4104	PAAR repeat-containing protein
J3K87_RS04455	COG3209	COG3209 Rhs family protein
J3K87_RS04465	COG0786	glutamate:sodium symporter activity
J3K87_RS04480	COG0640	Transcriptional regulator
J3K87_RS04560	COG2351	hydroxyisourate hydrolase activity
J3K87_RS04570	COG0586	Pfam SNARE associated Golgi protein
J3K87_RS04575	COG0187	DNA topoisomerase II activity
J3K87_RS04585	COG1349	DNA-binding transcription factor activity
J3K87_RS04590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J3K87_RS04600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J3K87_RS04605	COG4988	ABC transporter
J3K87_RS04610	COG2911	Protein conserved in bacteria
J3K87_RS04615	COG0729	surface antigen
J3K87_RS04620	COG2861	carbohydrate metabolic process
J3K87_RS04625	COG4942	peptidase
J3K87_RS04630	COG0588	phosphoglycerate mutase activity
J3K87_RS04640	COG0572	uridine kinase
J3K87_RS04645	COG0717	Belongs to the dCTP deaminase family
J3K87_RS04650	COG1309	transcriptional regulator
J3K87_RS04655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_RS04660	COG0842	Transport permease protein
J3K87_RS04660	COG1129	ABC transporter
J3K87_RS04665	COG0842	Transport permease protein
J3K87_RS04675	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J3K87_RS04680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J3K87_RS04685	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J3K87_RS04705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J3K87_RS04710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J3K87_RS04720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3K87_RS04725	COG4166	transmembrane transport
J3K87_RS04735	COG0444	Belongs to the ABC transporter superfamily
J3K87_RS04740	COG4608	Belongs to the ABC transporter superfamily
J3K87_RS04750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J3K87_RS04760	COG0747	negative chemotaxis
J3K87_RS04765	COG0814	amino acid
J3K87_RS04770	COG1760	l-serine dehydratase
J3K87_RS04780	COG0135	phosphoribosylanthranilate isomerase activity
J3K87_RS04780	COG0134	indole-3-glycerol-phosphate synthase activity
J3K87_RS04785	COG3177	Filamentation induced by cAMP protein fic
J3K87_RS04790	COG3098	single-species biofilm formation
J3K87_RS04795	COG0564	pseudouridine synthase activity
J3K87_RS04800	COG3140	Belongs to the UPF0181 family
J3K87_RS04810	COG3025	triphosphatase activity
J3K87_RS04815	COG3106	COG3106 Predicted ATPase
J3K87_RS04820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J3K87_RS04830	COG1473	amidohydrolase
J3K87_RS04835	COG3069	C4-dicarboxylate transmembrane transporter activity
J3K87_RS04845	COG0495	leucyl-tRNA aminoacylation
J3K87_RS04850	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J3K87_RS04855	COG1466	dna polymerase III delta subunit
J3K87_RS04860	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J3K87_RS04865	COG0237	dephospho-CoA kinase activity
J3K87_RS04875	COG1459	type II secretion system
J3K87_RS04880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3K87_RS04885	COG4969	Belongs to the N-Me-Phe pilin family
J3K87_RS04890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J3K87_RS04900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J3K87_RS04905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J3K87_RS04910	COG0730	response to heat
J3K87_RS04915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J3K87_RS04920	COG0183	Belongs to the thiolase family
J3K87_RS04925	COG1250	3-hydroxyacyl-CoA dehydrogenase
J3K87_RS04925	COG1024	Enoyl-CoA hydratase
J3K87_RS04940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J3K87_RS04950	COG0437	4 iron, 4 sulfur cluster binding
J3K87_RS04955	COG2864	formate dehydrogenase
J3K87_RS04960	COG3058	Necessary for formate dehydrogenase activity
J3K87_RS04990	COG1560	Kdo2-lipid A biosynthetic process
J3K87_RS04995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J3K87_RS05005	COG0302	gtp cyclohydrolase
J3K87_RS05010	COG3642	lipopolysaccharide core region biosynthetic process
J3K87_RS05020	COG0110	maltose O-acetyltransferase activity
J3K87_RS05030	COG0583	DNA-binding transcription factor activity
J3K87_RS05050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J3K87_RS05055	COG0215	cysteine-tRNA ligase activity
J3K87_RS05060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J3K87_RS05065	COG0617	tRNA 3'-terminal CCA addition
J3K87_RS05090	COG2975	iron-sulfur cluster assembly
J3K87_RS05095	COG0633	Ferredoxin
J3K87_RS05100	COG0443	Heat shock 70 kDa protein
J3K87_RS05115	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J3K87_RS05125	COG0822	iron-sulfur transferase activity
J3K87_RS05130	COG1104	cysteine desulfurase activity
J3K87_RS05135	COG1959	2 iron, 2 sulfur cluster binding
J3K87_RS05145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J3K87_RS05150	COG5002	protein histidine kinase activity
J3K87_RS05150	COG2198	Histidine kinase
J3K87_RS05150	COG0784	Response regulator, receiver
J3K87_RS05155	COG0697	spore germination
J3K87_RS05160	COG2840	Smr protein MutS2
J3K87_RS05165	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J3K87_RS05170	COG2226	methyltransferase
J3K87_RS05175	COG2830	Protein of unknown function (DUF452)
J3K87_RS05180	COG0156	8-amino-7-oxononanoate synthase activity
J3K87_RS05185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J3K87_RS05195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J3K87_RS05200	COG2027	D-alanyl-D-alanine carboxypeptidase
J3K87_RS05220	COG2801	Transposase and inactivated derivatives
J3K87_RS05230	COG2856	Zn peptidase
J3K87_RS05235	COG3620	sequence-specific DNA binding
J3K87_RS05270	COG1444	tRNA N-acetyltransferase activity
J3K87_RS05275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J3K87_RS05280	COG0138	bifunctional purine biosynthesis protein purh
J3K87_RS05285	COG2801	Transposase and inactivated derivatives
J3K87_RS05305	COG3210	domain, Protein
J3K87_RS05310	COG2831	hemolysin activation secretion protein
J3K87_RS05320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3K87_RS05330	COG3078	GTPase activator activity
J3K87_RS05340	COG0786	glutamate:sodium symporter activity
J3K87_RS05345	COG3112	Uncharacterised protein family (UPF0231)
J3K87_RS05355	COG2350	Protein conserved in bacteria
J3K87_RS05360	COG1607	acyl-coa hydrolase
J3K87_RS05375	COG3092	negative regulation of chromosome organization
J3K87_RS05385	COG2056	Na+-H+ antiporter family
J3K87_RS05390	COG0708	Exodeoxyribonuclease III
J3K87_RS05395	COG0583	DNA-binding transcription factor activity
J3K87_RS05415	COG0254	rRNA binding
J3K87_RS05430	COG0753	catalase activity
J3K87_RS05435	COG2963	transposase activity
J3K87_RS05445	COG1408	metallophosphoesterase
J3K87_RS05450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J3K87_RS05455	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J3K87_RS05460	COG1085	galactose-1-phosphate uridylyltransferase
J3K87_RS05470	COG2017	converts alpha-aldose to the beta-anomer
J3K87_RS05490	COG0489	protein tyrosine kinase activity
J3K87_RS05500	COG2095	MarC family integral membrane protein
J3K87_RS05505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J3K87_RS05515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J3K87_RS05520	COG2354	Protein conserved in bacteria
J3K87_RS05525	COG3071	HemY protein
J3K87_RS05530	COG2959	enzyme of heme biosynthesis
J3K87_RS05540	COG0181	hydroxymethylbilane synthase activity
J3K87_RS05545	COG1454	alcohol dehydrogenase
J3K87_RS05545	COG1012	belongs to the aldehyde dehydrogenase family
J3K87_RS05570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J3K87_RS05575	COG2364	Membrane
J3K87_RS05580	COG0800	Aldolase
J3K87_RS05585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J3K87_RS05590	COG1904	glucuronate isomerase
J3K87_RS05600	COG2186	Transcriptional regulator
J3K87_RS05610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J3K87_RS05610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J3K87_RS05615	COG1216	Glycosyl transferase, family 2
J3K87_RS05620	COG1216	Glycosyl transferase, family 2
J3K87_RS05630	COG3306	glycosyltransferase involved in LPS biosynthesis
J3K87_RS05640	COG5039	Polysaccharide pyruvyl transferase
J3K87_RS05645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J3K87_RS05650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J3K87_RS05655	COG1605	Chorismate mutase
J3K87_RS05655	COG0077	Prephenate dehydratase
J3K87_RS05660	COG0339	signal peptide processing
J3K87_RS05665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J3K87_RS05670	COG1882	Formate acetyltransferase
J3K87_RS05675	COG2116	formate transmembrane transporter activity
J3K87_RS05680	COG1238	metal cluster binding
J3K87_RS05685	COG0501	Belongs to the peptidase M48B family
J3K87_RS05695	COG2431	L-lysine efflux transmembrane transporter activity
J3K87_RS05700	COG1169	isochorismate synthase
J3K87_RS05705	COG0436	Aminotransferase
J3K87_RS05710	COG2962	Rard protein
J3K87_RS05715	COG2962	Rard protein
J3K87_RS05720	COG1280	lysine exporter protein (LysE YggA)
J3K87_RS05725	COG4771	TonB-dependent receptor
J3K87_RS05725	COG1629	transport
J3K87_RS05730	COG0748	coenzyme F420 binding
J3K87_RS05740	COG4235	cytochrome complex assembly
J3K87_RS05740	COG3088	subunit of a heme lyase
J3K87_RS05745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J3K87_RS05750	COG1138	Cytochrome C-type biogenesis protein
J3K87_RS05755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J3K87_RS05755	COG0475	glutathione-regulated potassium exporter activity
J3K87_RS05765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J3K87_RS05775	COG3111	PFAM Bacterial OB fold (BOF) protein
J3K87_RS05790	COG0745	RESPONSE REGULATOR receiver
J3K87_RS05795	COG0642	Histidine kinase
J3K87_RS05800	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J3K87_RS05805	COG1862	Preprotein translocase
J3K87_RS05810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J3K87_RS05815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J3K87_RS05820	COG1528	Iron-storage protein
J3K87_RS05825	COG1528	Iron-storage protein
J3K87_RS05830	COG2252	PERMEase
J3K87_RS05835	COG0424	maF-like protein
J3K87_RS05845	COG0301	tRNA thio-modification
J3K87_RS05845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J3K87_RS05850	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J3K87_RS05855	COG0330	HflC and HflK could
J3K87_RS05860	COG0330	HflC and HflK could
J3K87_RS05865	COG3118	belongs to the thioredoxin family
J3K87_RS05885	COG0531	amino acid
J3K87_RS05890	COG0531	amino acid
J3K87_RS05905	COG3047	cAMP biosynthetic process
J3K87_RS05910	COG0542	response to heat
J3K87_RS05915	COG0798	PFAM Bile acid sodium symporter
J3K87_RS05920	COG1393	Belongs to the ArsC family
J3K87_RS05930	COG1027	Aspartate ammonia-lyase
J3K87_RS05940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J3K87_RS05945	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J3K87_RS05945	COG3583	domain protein
J3K87_RS05945	COG3064	Membrane
J3K87_RS05955	COG0720	synthase
J3K87_RS05960	COG0602	queuosine metabolic process
J3K87_RS05985	COG0795	lipopolysaccharide-transporting ATPase activity
J3K87_RS05990	COG0795	lipopolysaccharide-transporting ATPase activity
J3K87_RS06000	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J3K87_RS06010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J3K87_RS06020	COG0861	Integral membrane protein TerC family
J3K87_RS06040	COG1051	belongs to the nudix hydrolase family
J3K87_RS06045	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
J3K87_RS06055	COG1965	Belongs to the frataxin family
J3K87_RS06065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J3K87_RS06070	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J3K87_RS06075	COG0564	pseudouridine synthase activity
J3K87_RS06085	COG0205	6-phosphofructokinase activity
J3K87_RS06090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J3K87_RS06095	COG1525	nuclease
J3K87_RS06100	COG1115	amino acid carrier protein
J3K87_RS06105	COG0628	permease
J3K87_RS06115	COG0826	peptidase U32
J3K87_RS06120	COG3307	-O-antigen
J3K87_RS06125	COG1519	Transferase
J3K87_RS06135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J3K87_RS06140	COG0802	atpase or kinase
J3K87_RS06145	COG1388	LysM domain
J3K87_RS06145	COG0860	N-Acetylmuramoyl-L-alanine amidase
J3K87_RS06155	COG2960	long-chain fatty acid transporting porin activity
J3K87_RS06180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J3K87_RS06190	COG0551	DNA topoisomerase type I activity
J3K87_RS06200	COG2137	regulation of response to DNA damage stimulus
J3K87_RS06205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J3K87_RS06210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J3K87_RS06220	COG1322	Protein conserved in bacteria
J3K87_RS06225	COG0512	Glutamine amidotransferase of anthranilate synthase
J3K87_RS06235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J3K87_RS06240	COG0494	nUDIX hydrolase
J3K87_RS06245	COG0217	transcriptional regulatory protein
J3K87_RS06255	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J3K87_RS06260	COG0612	Peptidase, M16
J3K87_RS06265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J3K87_RS06270	COG0471	metal ion transport
J3K87_RS06275	COG0583	DNA-binding transcription factor activity
J3K87_RS06280	COG3266	domain, Protein
J3K87_RS06285	COG1187	pseudouridine synthase activity
J3K87_RS06290	COG0009	L-threonylcarbamoyladenylate synthase
J3K87_RS06295	COG2837	iron assimilation
J3K87_RS06300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J3K87_RS06305	COG0512	Glutamine amidotransferase of anthranilate synthase
J3K87_RS06315	COG2226	methyltransferase
J3K87_RS06320	COG2268	Band 7 protein
J3K87_RS06325	COG2841	Protein conserved in bacteria
J3K87_RS06330	COG0359	binds to the 23S rRNA
J3K87_RS06340	COG2965	DNA replication, synthesis of RNA primer
J3K87_RS06355	COG3201	nicotinamide mononucleotide transporter
J3K87_RS06360	COG2976	Protein conserved in bacteria
J3K87_RS06370	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J3K87_RS06375	COG1426	Protein conserved in bacteria
J3K87_RS06380	COG0659	secondary active sulfate transmembrane transporter activity
J3K87_RS06390	COG0673	inositol 2-dehydrogenase activity
J3K87_RS06395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J3K87_RS06395	COG0475	glutathione-regulated potassium exporter activity
J3K87_RS06420	COG2207	Transcriptional regulator
J3K87_RS06430	COG1902	pentaerythritol trinitrate reductase activity
J3K87_RS06435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J3K87_RS06440	COG2084	Dehydrogenase
J3K87_RS06445	COG0778	Nitroreductase
J3K87_RS06450	COG2095	MarC family integral membrane protein
J3K87_RS06465	COG0625	glutathione transferase activity
J3K87_RS06485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J3K87_RS06500	COG1275	C4-dicarboxylate transporter malic acid transport protein
J3K87_RS06505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J3K87_RS06515	COG1132	(ABC) transporter
J3K87_RS06520	COG1854	S-ribosylhomocysteine lyase activity
J3K87_RS06525	COG3008	intermembrane lipid transfer
J3K87_RS06530	COG0735	belongs to the Fur family
J3K87_RS06535	COG0716	FMN binding
J3K87_RS06545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J3K87_RS06550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J3K87_RS06555	COG2252	PERMEase
J3K87_RS06560	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J3K87_RS06565	COG2081	HI0933 family
J3K87_RS06570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J3K87_RS06580	COG0560	Phosphoserine phosphatase
J3K87_RS06595	COG0058	SHG alpha-glucan phosphorylase activity
J3K87_RS06600	COG2909	trisaccharide binding
J3K87_RS06610	COG4580	involved in the transport of maltose and maltodextrins
J3K87_RS06615	COG3842	ATPase activity
J3K87_RS06630	COG3833	ABC-type maltose transport systems, permease component
J3K87_RS06635	COG1640	4-alpha-glucanotransferase
J3K87_RS06640	COG1966	Carbon starvation protein
J3K87_RS06645	COG0084	hydrolase, TatD family'
J3K87_RS06650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J3K87_RS06660	COG0778	Nitroreductase
J3K87_RS06675	COG4172	Belongs to the ABC transporter superfamily
J3K87_RS06680	COG0191	fructose-bisphosphate aldolase activity
J3K87_RS06685	COG0126	phosphoglycerate kinase activity
J3K87_RS06690	COG0471	metal ion transport
J3K87_RS06695	COG0471	metal ion transport
J3K87_RS06700	COG0471	metal ion transport
J3K87_RS06705	COG0187	DNA topoisomerase II activity
J3K87_RS06710	COG5002	protein histidine kinase activity
J3K87_RS06715	COG0745	RESPONSE REGULATOR receiver
J3K87_RS06740	COG0789	Transcriptional regulator
J3K87_RS06750	COG2217	Heavy metal translocating P-type atpase
J3K87_RS06760	COG0300	oxidoreductase activity
J3K87_RS06765	COG0778	Nitroreductase
J3K87_RS06770	COG0616	signal peptide processing
J3K87_RS06775	COG3719	Belongs to the RNase T2 family
J3K87_RS06785	COG1252	NADH dehydrogenase
J3K87_RS06790	COG2183	response to ionizing radiation
J3K87_RS06795	COG3063	Type IV pilus biogenesis stability protein PilW
J3K87_RS06835	COG2161	toxin-antitoxin pair type II binding
J3K87_RS06840	COG4115	mRNA cleavage
J3K87_RS06845	COG2835	tetraacyldisaccharide 4'-kinase activity
J3K87_RS06850	COG1663	tetraacyldisaccharide 4'-kinase activity
J3K87_RS06855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J3K87_RS06860	COG0740	serine-type endopeptidase activity
J3K87_RS06865	COG2166	iron-sulfur cluster assembly
J3K87_RS06885	COG0488	(ABC) transporter
J3K87_RS06890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J3K87_RS06905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J3K87_RS06910	COG5007	Belongs to the BolA IbaG family
J3K87_RS06920	COG2854	intermembrane phospholipid transfer
J3K87_RS06925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J3K87_RS06930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J3K87_RS06935	COG1127	ABC transporter
J3K87_RS06940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3K87_RS06945	COG1090	epimerase
J3K87_RS06965	COG0563	adenylate kinase activity
J3K87_RS06975	COG2814	Major facilitator Superfamily
J3K87_RS07005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J3K87_RS07015	COG1794	racemase activity, acting on amino acids and derivatives
J3K87_RS07020	COG2814	Major facilitator Superfamily
J3K87_RS07025	COG0363	glucosamine-6-phosphate deaminase activity
J3K87_RS07030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J3K87_RS07035	COG1218	3'(2'),5'-bisphosphate nucleotidase
J3K87_RS07040	COG0494	nUDIX hydrolase
J3K87_RS07045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J3K87_RS07055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J3K87_RS07060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J3K87_RS07075	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J3K87_RS07080	COG1178	ABC-type Fe3 transport system permease component
J3K87_RS07085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_RS07090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J3K87_RS07095	COG2190	(PTS) system
J3K87_RS07105	COG0210	DNA helicase
J3K87_RS07110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J3K87_RS07115	COG0409	Hydrogenase expression formation protein
J3K87_RS07120	COG0309	Hydrogenase expression formation protein (HypE)
J3K87_RS07145	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J3K87_RS07150	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
J3K87_RS07155	COG0437	4 iron, 4 sulfur cluster binding
J3K87_RS07160	COG5557	Pfam Polysulphide reductase, NrfD
J3K87_RS07165	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J3K87_RS07170	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J3K87_RS07175	COG1773	rubredoxin
J3K87_RS07180	COG0298	carbon dioxide binding
J3K87_RS07185	COG0375	protein maturation
J3K87_RS07220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J3K87_RS07225	COG0308	aminopeptidase N
J3K87_RS07230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J3K87_RS07235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J3K87_RS07240	COG0295	cytidine deaminase activity
J3K87_RS07245	COG2177	Part of the ABC transporter FtsEX involved in
J3K87_RS07250	COG2884	Cell division ATP-binding protein ftsE
J3K87_RS07255	COG0552	protein localization to endoplasmic reticulum
J3K87_RS07260	COG0742	ribosomal rna small subunit methyltransferase
J3K87_RS07265	COG3099	Belongs to the UPF0263 family
J3K87_RS07270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J3K87_RS07280	COG4160	amino acid transport
J3K87_RS07285	COG4215	(ABC) transporter
J3K87_RS07290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3K87_RS07295	COG1126	abc transporter atp-binding protein
J3K87_RS07300	COG1881	PFAM PEBP family protein
J3K87_RS07310	COG3620	sequence-specific DNA binding
J3K87_RS07320	COG4232	protein-disulfide reductase activity
J3K87_RS07325	COG3101	peptidyl-lysine hydroxylation
J3K87_RS07335	COG3107	peptidoglycan biosynthetic process
J3K87_RS07340	COG0792	nuclease activity
J3K87_RS07345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J3K87_RS07380	COG1138	Cytochrome C-type biogenesis protein
J3K87_RS07390	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J3K87_RS07395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J3K87_RS07400	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J3K87_RS07405	COG4133	protoheme IX ABC transporter activity
J3K87_RS07410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J3K87_RS07440	COG3630	sodium ion export across plasma membrane
J3K87_RS07450	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J3K87_RS07455	COG2824	Alkylphosphonate utilization operon protein PhnA
J3K87_RS07460	COG1858	cytochrome C peroxidase
J3K87_RS07470	COG0762	integral membrane protein
J3K87_RS07475	COG3171	Protein conserved in bacteria
J3K87_RS07480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J3K87_RS07485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3K87_RS07490	COG0416	fatty acid biosynthetic process
J3K87_RS07495	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J3K87_RS07500	COG1399	metal-binding, possibly nucleic acid-binding protein
J3K87_RS07505	COG4137	Cytochrome C assembly protein
J3K87_RS07510	COG4536	flavin adenine dinucleotide binding
J3K87_RS07515	COG0733	neurotransmitter:sodium symporter activity
J3K87_RS07525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J3K87_RS07525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_RS07530	COG3715	PTS system
J3K87_RS07535	COG3716	PTS system mannose fructose sorbose family IID component
J3K87_RS07570	COG1840	ABC-type Fe3 transport system, periplasmic component
J3K87_RS07585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J3K87_RS07600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J3K87_RS07605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J3K87_RS07610	COG0049	tRNA binding
J3K87_RS07615	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J3K87_RS07620	COG0859	PFAM glycosyl transferase family 9
J3K87_RS07625	COG0859	PFAM glycosyl transferase family 9
J3K87_RS07635	COG3266	domain, Protein
J3K87_RS07635	COG3061	Opacity-associated protein A
J3K87_RS07640	COG1555	photosystem II stabilization
J3K87_RS07665	COG0732	type I restriction modification DNA specificity domain
J3K87_RS07670	COG4974	Belongs to the 'phage' integrase family
J3K87_RS07680	COG2918	glutathione biosynthetic process
J3K87_RS07680	COG1181	Belongs to the D-alanine--D-alanine ligase family
J3K87_RS07690	COG0814	amino acid
J3K87_RS07695	COG3691	Protein conserved in bacteria
J3K87_RS07700	COG4989	oxidoreductase activity
J3K87_RS07705	COG1022	Amp-dependent synthetase and ligase
J3K87_RS07730	COG4211	Belongs to the binding-protein-dependent transport system permease family
J3K87_RS07735	COG1129	ABC transporter
J3K87_RS07740	COG1879	ABC-type sugar transport system periplasmic component
J3K87_RS07745	COG2885	chlorophyll binding
J3K87_RS07745	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J3K87_RS07750	COG0277	FAD linked oxidase domain protein
J3K87_RS07750	COG0247	lactate metabolic process
J3K87_RS07755	COG2050	protein possibly involved in aromatic compounds catabolism
J3K87_RS07765	COG3005	denitrification pathway
J3K87_RS07770	COG3043	anaerobic respiration
J3K87_RS07775	COG0348	domain, Protein
J3K87_RS07780	COG0437	4 iron, 4 sulfur cluster binding
J3K87_RS07785	COG0243	molybdopterin cofactor binding
J3K87_RS07795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J3K87_RS07800	COG2249	NAD(P)H dehydrogenase (quinone) activity
J3K87_RS07815	COG1530	ribonuclease E activity
J3K87_RS07825	COG1755	Isoprenylcysteine carboxyl methyltransferase
J3K87_RS07835	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J3K87_RS07845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J3K87_RS07845	COG0678	peroxiredoxin activity
J3K87_RS07850	COG0583	DNA-binding transcription factor activity
J3K87_RS07855	COG1309	transcriptional regulator
J3K87_RS07860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J3K87_RS07865	COG0557	exoribonuclease II activity
J3K87_RS07875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J3K87_RS07880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J3K87_RS07890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J3K87_RS07910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J3K87_RS07915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J3K87_RS07920	COG0562	UDP-galactopyranose mutase
J3K87_RS07925	COG2244	polysaccharide biosynthetic process
J3K87_RS07935	COG0438	transferase activity, transferring glycosyl groups
J3K87_RS07945	COG0438	transferase activity, transferring glycosyl groups
J3K87_RS07955	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
J3K87_RS07965	COG1575	Belongs to the MenA family. Type 1 subfamily
J3K87_RS07970	COG4804	nuclease activity
J3K87_RS07975	COG1720	tRNA m6t6A37 methyltransferase activity
J3K87_RS07985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J3K87_RS08005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J3K87_RS08010	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J3K87_RS08015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J3K87_RS08040	COG0825	malonyl-CoA metabolic process
J3K87_RS08050	COG0204	Acyl-transferase
J3K87_RS08055	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J3K87_RS08080	COG0783	Belongs to the Dps family
J3K87_RS08095	COG1289	transmembrane transporter activity
J3K87_RS08100	COG1803	Methylglyoxal synthase
J3K87_RS08105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J3K87_RS08130	COG2153	protein acetylation
J3K87_RS08135	COG2927	DNA polymerase III (CHI subunit)
J3K87_RS08140	COG1652	LysM domain
J3K87_RS08145	COG0544	peptidyl-prolyl cis-trans isomerase activity
J3K87_RS08150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J3K87_RS08165	COG1045	serine acetyltransferase
J3K87_RS08170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J3K87_RS08200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J3K87_RS08215	COG0521	Mo-molybdopterin cofactor biosynthetic process
J3K87_RS08225	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J3K87_RS08235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J3K87_RS08250	COG0625	glutathione transferase activity
J3K87_RS08255	COG0019	diaminopimelate decarboxylase activity
J3K87_RS08265	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J3K87_RS08270	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J3K87_RS08275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J3K87_RS08280	COG1053	succinate dehydrogenase
J3K87_RS08285	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J3K87_RS08295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J3K87_RS08300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J3K87_RS08315	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J3K87_RS08320	COG2264	protein methyltransferase activity
J3K87_RS08340	COG0037	tRNA processing
J3K87_RS08350	COG4974	Belongs to the 'phage' integrase family
J3K87_RS08405	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J3K87_RS08420	COG1151	hydroxylamine reductase activity
J3K87_RS08425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J3K87_RS08430	COG2244	polysaccharide biosynthetic process
J3K87_RS08435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J3K87_RS08445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J3K87_RS08450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J3K87_RS08455	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
J3K87_RS08475	COG0728	peptidoglycan biosynthetic process
J3K87_RS08480	COG0268	Binds directly to 16S ribosomal RNA
J3K87_RS08485	COG0569	domain protein
J3K87_RS08490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J3K87_RS08495	COG3276	selenocysteine insertion sequence binding
J3K87_RS08500	COG1921	L-seryl-tRNASec selenium transferase activity
J3K87_RS08510	COG0716	FMN binding
J3K87_RS08530	COG1629	transport
J3K87_RS08530	COG4771	TonB-dependent receptor
J3K87_RS08565	COG3545	Serine hydrolase
J3K87_RS08585	COG2826	transposase and inactivated derivatives, IS30 family
J3K87_RS08595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J3K87_RS08595	COG1215	transferase activity, transferring glycosyl groups
J3K87_RS08625	COG1119	ATPase activity
J3K87_RS08640	COG1739	Uncharacterized protein family UPF0029
J3K87_RS08645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J3K87_RS08650	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
J3K87_RS08655	COG1970	mechanosensitive ion channel activity
J3K87_RS08665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J3K87_RS08670	COG0321	lipoyl(octanoyl) transferase activity
J3K87_RS08675	COG2921	Belongs to the UPF0250 family
J3K87_RS08680	COG1686	Belongs to the peptidase S11 family
J3K87_RS08685	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J3K87_RS08690	COG0772	Belongs to the SEDS family
J3K87_RS08695	COG0768	penicillin binding
J3K87_RS08700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J3K87_RS08705	COG0799	negative regulation of ribosome biogenesis
J3K87_RS08715	COG1126	abc transporter atp-binding protein
J3K87_RS08730	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
J3K87_RS08740	COG3691	Protein conserved in bacteria
J3K87_RS08785	COG0832	Belongs to the urease beta subunit family
J3K87_RS08790	COG0831	urea catabolic process
J3K87_RS08800	COG1122	ATPase activity
J3K87_RS08810	COG0310	cobalt ion transport
J3K87_RS08815	COG0310	cobalt ion transport
J3K87_RS08820	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
J3K87_RS08825	COG0583	DNA-binding transcription factor activity
J3K87_RS08835	COG0471	metal ion transport
J3K87_RS08835	COG0490	domain, Protein
J3K87_RS08840	COG3722	fumarate hydratase activity
J3K87_RS08845	COG0246	Mannitol dehydrogenase
J3K87_RS08855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J3K87_RS08860	COG1349	DNA-binding transcription factor activity
J3K87_RS08875	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
J3K87_RS08890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J3K87_RS08895	COG2900	Belongs to the SlyX family
J3K87_RS08900	COG0545	Peptidyl-prolyl cis-trans isomerase
J3K87_RS08905	COG2964	Protein conserved in bacteria
J3K87_RS08910	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J3K87_RS08920	COG2168	tRNA wobble position uridine thiolation
J3K87_RS08970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J3K87_RS09005	COG0561	phosphatase activity
J3K87_RS09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3K87_RS09015	COG3012	SEC-C Motif Domain Protein
J3K87_RS09025	COG3716	PTS system mannose fructose sorbose family IID component
J3K87_RS09030	COG3715	PTS system
J3K87_RS09035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J3K87_RS09035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J3K87_RS09040	COG2610	gluconate transmembrane transporter activity
J3K87_RS09045	COG3265	gluconokinase activity
J3K87_RS09050	COG1609	Transcriptional regulator
J3K87_RS09060	COG1869	D-ribose catabolic process
J3K87_RS09070	COG1172	Belongs to the binding-protein-dependent transport system permease family
J3K87_RS09075	COG1879	ABC-type sugar transport system periplasmic component
J3K87_RS09080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J3K87_RS09085	COG0243	molybdopterin cofactor binding
J3K87_RS09090	COG0437	4 iron, 4 sulfur cluster binding
J3K87_RS09095	COG3302	dmso reductase anchor subunit
J3K87_RS09100	COG3381	protein complex oligomerization
J3K87_RS09105	COG2221	Nitrite and sulphite reductase 4Fe-4S
J3K87_RS09105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J3K87_RS09135	COG1349	DNA-binding transcription factor activity
J3K87_RS09140	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
J3K87_RS09145	COG1070	Carbohydrate kinase
J3K87_RS09150	COG4154	Belongs to the RbsD FucU family
J3K87_RS09155	COG0235	Class ii aldolase
J3K87_RS09160	COG0738	Major facilitator superfamily
J3K87_RS09165	COG1454	alcohol dehydrogenase
J3K87_RS09170	COG3477	response to acidic pH
J3K87_RS09175	COG0765	amino acid transport
J3K87_RS09185	COG1126	abc transporter atp-binding protein
J3K87_RS09190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3K87_RS09210	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J3K87_RS09235	COG3623	hexulose-6-phosphate isomerase
J3K87_RS09240	COG0235	Class ii aldolase
J3K87_RS09245	COG0545	Peptidyl-prolyl cis-trans isomerase
J3K87_RS09255	COG1476	TRANSCRIPTIONal
J3K87_RS09265	COG4783	chaperone-mediated protein folding
J3K87_RS09270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3K87_RS09280	COG0758	DNA mediated transformation
J3K87_RS09285	COG1297	OPT oligopeptide transporter protein
J3K87_RS09300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J3K87_RS09310	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J3K87_RS09315	COG0081	regulation of translation
J3K87_RS09320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J3K87_RS09325	COG0222	ribosome binding
J3K87_RS09395	COG1487	ribonuclease activity
J3K87_RS09420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J3K87_RS09430	COG0346	lactoylglutathione lyase activity
J3K87_RS09435	COG1194	a g-specific adenine glycosylase
J3K87_RS09440	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J3K87_RS09445	COG0741	lytic transglycosylase activity
J3K87_RS09460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J3K87_RS09465	COG0737	Belongs to the 5'-nucleotidase family
J3K87_RS09470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J3K87_RS09475	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J3K87_RS09480	COG0606	chelatase, subunit chli
J3K87_RS09495	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J3K87_RS09505	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
J3K87_RS09515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J3K87_RS09525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J3K87_RS09540	COG0051	transcription antitermination factor activity, RNA binding
J3K87_RS09545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J3K87_RS09550	COG0088	Forms part of the polypeptide exit tunnel
J3K87_RS09555	COG0089	rRNA binding
J3K87_RS09560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J3K87_RS09565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J3K87_RS09570	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J3K87_RS09575	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J3K87_RS09580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J3K87_RS09585	COG0255	Belongs to the universal ribosomal protein uL29 family
J3K87_RS09590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J3K87_RS09600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J3K87_RS09605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J3K87_RS09610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J3K87_RS09615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J3K87_RS09620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J3K87_RS09625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J3K87_RS09630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J3K87_RS09635	COG1841	ribosomal large subunit assembly
J3K87_RS09640	COG0200	Binds to the 23S rRNA
J3K87_RS09645	COG0201	protein transport
J3K87_RS09655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J3K87_RS09660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J3K87_RS09665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J3K87_RS09670	COG0202	RNA polymerase activity
J3K87_RS09680	COG0228	four-way junction DNA binding
J3K87_RS09685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J3K87_RS09690	COG0336	Belongs to the RNA methyltransferase TrmD family
J3K87_RS09695	COG0335	large ribosomal subunit rRNA binding
J3K87_RS09700	COG2850	peptidyl-arginine hydroxylation
J3K87_RS09705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J3K87_RS09710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J3K87_RS09755	COG2852	Protein conserved in bacteria
J3K87_RS09780	COG2832	Protein of unknown function (DUF454)
J3K87_RS09790	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3K87_RS09800	COG0084	hydrolase, TatD family'
J3K87_RS09815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3K87_RS09825	COG0470	DNA polymerase III
J3K87_RS09830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J3K87_RS09835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J3K87_RS09855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3K87_RS09860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J3K87_RS09865	COG0254	rRNA binding
J3K87_RS09870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J3K87_RS09875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J3K87_RS09880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J3K87_RS09885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J3K87_RS09895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J3K87_RS09920	COG1595	DNA-templated transcription, initiation
J3K87_RS09935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J3K87_RS09960	COG2502	aspartate--ammonia ligase
J3K87_RS09965	COG1522	sequence-specific DNA binding
J3K87_RS09970	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J3K87_RS09975	COG3161	chorismate lyase activity
J3K87_RS10015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J3K87_RS10040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J3K87_RS10050	COG4208	sulfate ABC transporter
J3K87_RS10055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J3K87_RS10060	COG1304	FMN binding
J3K87_RS10070	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J3K87_RS10080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J3K87_RS10085	COG2995	paraquat-inducible protein a
J3K87_RS10090	COG1305	Transglutaminase-like
J3K87_RS10100	COG2608	mercury ion transmembrane transporter activity
J3K87_RS10105	COG1979	alcohol dehydrogenase
J3K87_RS10110	COG0583	DNA-binding transcription factor activity
J3K87_RS10115	COG2171	N-acyltransferase activity
J3K87_RS10120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J3K87_RS10130	COG0511	ligase activity, forming carbon-carbon bonds
J3K87_RS10135	COG0439	Biotin carboxylase
J3K87_RS10145	COG3084	Protein conserved in bacteria
J3K87_RS10150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J3K87_RS10160	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J3K87_RS10160	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J3K87_RS10170	COG1876	peptidase activity
J3K87_RS10180	COG1393	Belongs to the ArsC family
J3K87_RS10190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J3K87_RS10195	COG0564	pseudouridine synthase activity
J3K87_RS10205	COG0668	transmembrane transport
J3K87_RS10210	COG0439	Biotin carboxylase
J3K87_RS10220	COG1025	Belongs to the peptidase M16 family
J3K87_RS10225	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J3K87_RS10250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J3K87_RS10255	COG1067	ATP-dependent peptidase activity
J3K87_RS10260	COG3120	sequence-specific DNA binding
J3K87_RS10265	COG0180	Tryptophanyl-tRNA synthetase
J3K87_RS10285	COG0730	response to heat
J3K87_RS10300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J3K87_RS10305	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J3K87_RS10310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J3K87_RS10315	COG2116	formate transmembrane transporter activity
J3K87_RS10345	COG1070	Carbohydrate kinase
J3K87_RS10350	COG2115	Belongs to the xylose isomerase family
J3K87_RS10355	COG4213	ABC transporter substrate-binding protein
J3K87_RS10360	COG1129	ABC transporter
J3K87_RS10365	COG4214	carbohydrate transport
J3K87_RS10370	COG1609	Transcriptional regulator
J3K87_RS10370	COG2207	Transcriptional regulator
J3K87_RS10375	COG3590	peptidase
J3K87_RS10385	COG4145	pantothenate transmembrane transporter activity
J3K87_RS10390	COG3924	membrane
J3K87_RS10395	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J3K87_RS10400	COG2853	Lipoprotein
J3K87_RS10405	COG0676	glucose-6-phosphate 1-epimerase activity
J3K87_RS10420	COG0726	polysaccharide deacetylase
J3K87_RS10420	COG1649	PFAM Uncharacterised BCR, COG1649
J3K87_RS10425	COG1215	transferase activity, transferring glycosyl groups
J3K87_RS10435	COG0149	triose-phosphate isomerase activity
J3K87_RS10445	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J3K87_RS10450	COG1238	metal cluster binding
J3K87_RS10465	COG1388	LysM domain
J3K87_RS10465	COG4942	peptidase
J3K87_RS10470	COG2818	Glycosylase
J3K87_RS10480	COG0700	Nucleoside recognition
J3K87_RS10485	COG3366	ferrous iron transmembrane transporter activity
J3K87_RS10495	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J3K87_RS10500	COG0594	ribonuclease P activity
J3K87_RS10505	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J3K87_RS10510	COG0174	glutamine synthetase
J3K87_RS10515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J3K87_RS10520	COG0494	nUDIX hydrolase
J3K87_RS10550	COG1490	D-aminoacyl-tRNA deacylase activity
J3K87_RS10555	COG1295	ribonuclease BN
J3K87_RS10570	COG1629	transport
J3K87_RS10570	COG4771	TonB-dependent receptor
J3K87_RS10610	COG1064	alcohol dehydrogenase
J3K87_RS10620	COG1923	regulation of RNA biosynthetic process
J3K87_RS10625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J3K87_RS10635	COG1694	Mazg nucleotide pyrophosphohydrolase
J3K87_RS10650	COG1309	transcriptional regulator
J3K87_RS10660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J3K87_RS10665	COG2003	Belongs to the UPF0758 family
J3K87_RS10670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J3K87_RS10675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J3K87_RS10690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J3K87_RS10695	COG0076	glutamate decarboxylase activity
J3K87_RS10700	COG0425	Belongs to the sulfur carrier protein TusA family
J3K87_RS10705	COG2391	methyltransferase activity
J3K87_RS10710	COG3085	chromosome segregation
J3K87_RS10730	COG0598	Magnesium transport protein CorA
J3K87_RS10735	COG2226	methyltransferase
J3K87_RS10750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J3K87_RS10755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J3K87_RS10760	COG0805	protein transport
J3K87_RS10780	COG1114	Component of the transport system for branched-chain amino acids
J3K87_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
J3K87_RS10790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J3K87_RS10795	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J3K87_RS10800	COG0142	geranyltranstransferase activity
J3K87_RS10810	COG0431	NADPH-dependent FMN reductase
J3K87_RS10815	COG2259	Doxx family
J3K87_RS10820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J3K87_RS10825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J3K87_RS10830	COG0697	spore germination
J3K87_RS10835	COG4783	chaperone-mediated protein folding
J3K87_RS10845	COG1040	competence protein
J3K87_RS10860	COG0456	acetyltransferase
J3K87_RS10865	COG0513	Belongs to the DEAD box helicase family
J3K87_RS10875	COG0747	negative chemotaxis
J3K87_RS10885	COG1584	GPR1 FUN34 yaaH family protein
J3K87_RS10890	COG1120	ATPase activity
J3K87_RS10925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J3K87_RS10930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J3K87_RS10950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J3K87_RS10965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J3K87_RS10965	COG0140	phosphoribosyl-ATP diphosphatase activity
J3K87_RS10970	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J3K87_RS10975	COG0024	Methionine aminopeptidase
J3K87_RS10990	COG1621	beta-fructofuranosidase activity
J3K87_RS10995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J3K87_RS11005	COG4591	ABC-type transport system involved in lipoprotein release permease component
J3K87_RS11010	COG1136	(ABC) transporter
J3K87_RS11015	COG4591	ABC-type transport system involved in lipoprotein release permease component
J3K87_RS11020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family