locus-tag	class	description
IMCC19121_RS00005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMCC19121_RS00010	COG2177	Part of the ABC transporter FtsEX involved in
IMCC19121_RS00015	COG2884	Cell division ATP-binding protein ftsE
IMCC19121_RS00020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMCC19121_RS00070	COG3480	Lon protease (S16) C-terminal proteolytic domain
IMCC19121_RS00075	COG1615	UPF0182 protein
IMCC19121_RS00090	COG0483	inositol monophosphate 1-phosphatase activity
IMCC19121_RS00095	COG1162	GTPase activity
IMCC19121_RS00100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IMCC19121_RS00105	COG2135	peptidase activity
IMCC19121_RS00110	COG1595	DNA-templated transcription, initiation
IMCC19121_RS00135	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC19121_RS00135	COG0567	Dehydrogenase, E1 component
IMCC19121_RS00150	COG0459	protein refolding
IMCC19121_RS00155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMCC19121_RS00160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC19121_RS00175	COG0802	atpase or kinase
IMCC19121_RS00210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMCC19121_RS00215	COG0736	holo-[acyl-carrier-protein] synthase activity
IMCC19121_RS00225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMCC19121_RS00230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC19121_RS00235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMCC19121_RS00240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMCC19121_RS00245	COG0101	tRNA pseudouridine synthase activity
IMCC19121_RS00250	COG0203	ribosomal protein L17
IMCC19121_RS00255	COG0202	RNA polymerase activity
IMCC19121_RS00260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMCC19121_RS00265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMCC19121_RS00270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMCC19121_RS00275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IMCC19121_RS00280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMCC19121_RS00310	COG0563	adenylate kinase activity
IMCC19121_RS00320	COG0200	Binds to the 23S rRNA
IMCC19121_RS00325	COG1841	ribosomal large subunit assembly
IMCC19121_RS00330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMCC19121_RS00340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMCC19121_RS00345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMCC19121_RS00350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMCC19121_RS00355	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMCC19121_RS00360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMCC19121_RS00365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMCC19121_RS00370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMCC19121_RS00375	COG0255	Belongs to the universal ribosomal protein uL29 family
IMCC19121_RS00385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMCC19121_RS00390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMCC19121_RS00395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMCC19121_RS00400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMCC19121_RS00405	COG0089	rRNA binding
IMCC19121_RS00410	COG0088	Forms part of the polypeptide exit tunnel
IMCC19121_RS00415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMCC19121_RS00420	COG0051	transcription antitermination factor activity, RNA binding
IMCC19121_RS00425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC19121_RS00430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMCC19121_RS00435	COG0049	tRNA binding
IMCC19121_RS00440	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMCC19121_RS00455	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMCC19121_RS00460	COG0085	RNA polymerase activity
IMCC19121_RS00465	COG0222	ribosome binding
IMCC19121_RS00470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMCC19121_RS00475	COG0081	regulation of translation
IMCC19121_RS00480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMCC19121_RS00500	COG0436	Aminotransferase
IMCC19121_RS00505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMCC19121_RS00510	COG0215	cysteine-tRNA ligase activity
IMCC19121_RS00520	COG2030	dehydratase
IMCC19121_RS00525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMCC19121_RS00545	COG0395	ABC-type sugar transport system, permease component
IMCC19121_RS00550	COG1175	transmembrane transport
IMCC19121_RS00560	COG2855	membrane
IMCC19121_RS00565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IMCC19121_RS00575	COG2721	sulfolactate sulfo-lyase activity
IMCC19121_RS00580	COG2721	sulfolactate sulfo-lyase activity
IMCC19121_RS00585	COG0673	inositol 2-dehydrogenase activity
IMCC19121_RS00595	COG3684	Belongs to the aldolase LacD family
IMCC19121_RS00605	COG2186	Transcriptional regulator
IMCC19121_RS00610	COG0395	ABC-type sugar transport system, permease component
IMCC19121_RS00615	COG1175	transmembrane transport
IMCC19121_RS00635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC19121_RS00645	COG1126	abc transporter atp-binding protein
IMCC19121_RS00650	COG0765	amino acid transport
IMCC19121_RS00665	COG1666	GTP binding
IMCC19121_RS00675	COG0574	Belongs to the PEP-utilizing enzyme family
IMCC19121_RS00675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMCC19121_RS00695	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC19121_RS00700	COG4214	carbohydrate transport
IMCC19121_RS00710	COG4213	ABC transporter substrate-binding protein
IMCC19121_RS00725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMCC19121_RS00730	COG0022	dehydrogenase e1 component
IMCC19121_RS00745	COG1609	Transcriptional regulator
IMCC19121_RS00750	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC19121_RS00785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC19121_RS00790	COG2301	Belongs to the HpcH HpaI aldolase family
IMCC19121_RS00800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC19121_RS00815	COG0142	geranyltranstransferase activity
IMCC19121_RS00840	COG0839	Belongs to the complex I subunit 6 family
IMCC19121_RS00845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC19121_RS00850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMCC19121_RS00855	COG1034	ATP synthesis coupled electron transport
IMCC19121_RS00860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IMCC19121_RS00870	COG0649	NAD binding
IMCC19121_RS00875	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC19121_RS00890	COG2226	methyltransferase
IMCC19121_RS00895	COG1268	BioY protein
IMCC19121_RS00900	COG1169	isochorismate synthase
IMCC19121_RS00905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IMCC19121_RS00910	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC19121_RS00915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMCC19121_RS00935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC19121_RS00945	COG0785	Cytochrome C biogenesis protein
IMCC19121_RS00950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC19121_RS00955	COG0406	alpha-ribazole phosphatase activity
IMCC19121_RS00975	COG1061	Type III restriction enzyme res subunit
IMCC19121_RS01000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMCC19121_RS01010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMCC19121_RS01035	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IMCC19121_RS01040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMCC19121_RS01045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IMCC19121_RS01050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMCC19121_RS01055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMCC19121_RS01060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMCC19121_RS01065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMCC19121_RS01070	COG0302	gtp cyclohydrolase
IMCC19121_RS01080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMCC19121_RS01085	COG0037	tRNA processing
IMCC19121_RS01090	COG0791	NLP P60 protein
IMCC19121_RS01110	COG0109	protoheme IX farnesyltransferase activity
IMCC19121_RS01145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMCC19121_RS01160	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IMCC19121_RS01175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC19121_RS01175	COG1845	cytochrome c oxidase, subunit III
IMCC19121_RS01180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMCC19121_RS01205	COG0339	signal peptide processing
IMCC19121_RS01210	COG1872	DUF167
IMCC19121_RS01250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC19121_RS01255	COG0047	phosphoribosylformylglycinamidine synthase activity
IMCC19121_RS01260	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC19121_RS01265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMCC19121_RS01270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMCC19121_RS01275	COG0151	Belongs to the GarS family
IMCC19121_RS01280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMCC19121_RS01285	COG0191	fructose-bisphosphate aldolase activity
IMCC19121_RS01290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC19121_RS01295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC19121_RS01320	COG1610	YqeY-like protein
IMCC19121_RS01335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMCC19121_RS01360	COG2197	response regulator
IMCC19121_RS01390	COG0531	amino acid
IMCC19121_RS01395	COG0590	tRNA wobble adenosine to inosine editing
IMCC19121_RS01405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMCC19121_RS01415	COG0586	Pfam SNARE associated Golgi protein
IMCC19121_RS01425	COG2862	Uncharacterized protein family, UPF0114
IMCC19121_RS01430	COG0488	(ABC) transporter
IMCC19121_RS01435	COG3844	kynureninase activity
IMCC19121_RS01450	COG0586	Pfam SNARE associated Golgi protein
IMCC19121_RS01460	COG3842	ATPase activity
IMCC19121_RS01465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMCC19121_RS01470	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC19121_RS01475	COG1177	transmembrane transport
IMCC19121_RS01505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMCC19121_RS01510	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IMCC19121_RS01520	COG4085	toxin activity
IMCC19121_RS01520	COG0737	Belongs to the 5'-nucleotidase family
IMCC19121_RS01520	COG1525	nuclease
IMCC19121_RS01535	COG0006	proline dipeptidase activity
IMCC19121_RS01540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMCC19121_RS01545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMCC19121_RS01550	COG1950	PFAM Membrane protein of
IMCC19121_RS01560	COG1053	succinate dehydrogenase
IMCC19121_RS01575	COG0561	phosphatase activity
IMCC19121_RS01580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMCC19121_RS01585	COG0077	Prephenate dehydratase
IMCC19121_RS01595	COG0631	protein serine/threonine phosphatase activity
IMCC19121_RS01600	COG0515	serine threonine protein kinase
IMCC19121_RS01605	COG0305	Participates in initiation and elongation during chromosome replication
IMCC19121_RS01620	COG0359	binds to the 23S rRNA
IMCC19121_RS01625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMCC19121_RS01635	COG0360	Binds together with S18 to 16S ribosomal RNA
IMCC19121_RS01645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMCC19121_RS01680	COG0492	ferredoxin-NADP+ reductase activity
IMCC19121_RS01685	COG3118	belongs to the thioredoxin family
IMCC19121_RS01690	COG3409	Peptidoglycan-binding domain 1 protein
IMCC19121_RS01690	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMCC19121_RS01695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC19121_RS01705	COG1192	Involved in chromosome partitioning
IMCC19121_RS01710	COG0357	Ribosomal RNA small subunit methyltransferase G
IMCC19121_RS01720	COG0706	membrane insertase activity
IMCC19121_RS01725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMCC19121_RS01730	COG0594	ribonuclease P activity
IMCC19121_RS01735	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IMCC19121_RS01740	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMCC19121_RS01745	COG0592	DNA-directed DNA polymerase activity
IMCC19121_RS01750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC19121_RS01755	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
IMCC19121_RS01760	COG0187	DNA topoisomerase II activity
IMCC19121_RS01765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC19121_RS01785	COG0705	Rhomboid family
IMCC19121_RS01800	COG0697	spore germination
IMCC19121_RS01805	COG1960	acyl-CoA dehydrogenase activity
IMCC19121_RS01810	COG0717	Belongs to the dCTP deaminase family
IMCC19121_RS01820	COG1704	LemA family
IMCC19121_RS01830	COG2205	protein histidine kinase activity
IMCC19121_RS01835	COG0745	RESPONSE REGULATOR receiver
IMCC19121_RS01840	COG2181	nitrate reductase activity
IMCC19121_RS01840	COG0247	lactate metabolic process
IMCC19121_RS01855	COG0443	Heat shock 70 kDa protein
IMCC19121_RS01860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMCC19121_RS01865	COG0484	heat shock protein binding
IMCC19121_RS01870	COG0789	Transcriptional regulator
IMCC19121_RS01880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMCC19121_RS01885	COG0586	Pfam SNARE associated Golgi protein
IMCC19121_RS01890	COG1653	transport
IMCC19121_RS01895	COG1175	transmembrane transport
IMCC19121_RS01900	COG0395	ABC-type sugar transport system, permease component
IMCC19121_RS01905	COG2723	6-phospho-beta-galactosidase activity
IMCC19121_RS01910	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IMCC19121_RS01915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMCC19121_RS01915	COG1754	DNA topoisomerase type I activity
IMCC19121_RS01920	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMCC19121_RS01925	COG0470	DNA polymerase III
IMCC19121_RS01940	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC19121_RS01945	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IMCC19121_RS01950	COG0579	oxidoreductase
IMCC19121_RS01955	COG0546	phosphoglycolate phosphatase activity
IMCC19121_RS01960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC19121_RS01965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IMCC19121_RS01965	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IMCC19121_RS01970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC19121_RS01985	COG3959	Transketolase, thiamine diphosphate binding domain
IMCC19121_RS01990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMCC19121_RS01995	COG2813	Specifically methylates the guanine in position
IMCC19121_RS02000	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IMCC19121_RS02010	COG2192	nodulation
IMCC19121_RS02040	COG1086	Polysaccharide biosynthesis protein
IMCC19121_RS02045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMCC19121_RS02055	COG2089	acid synthase
IMCC19121_RS02060	COG1083	cytidylyl-transferase
IMCC19121_RS02065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMCC19121_RS02070	COG0107	imidazoleglycerol-phosphate synthase activity
IMCC19121_RS02085	COG0367	asparagine synthase
IMCC19121_RS02100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC19121_RS02130	COG1216	Glycosyl transferase, family 2
IMCC19121_RS02140	COG0438	transferase activity, transferring glycosyl groups
IMCC19121_RS02145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC19121_RS02155	COG2226	methyltransferase
IMCC19121_RS02155	COG1073	alpha beta
IMCC19121_RS02175	COG1091	dTDP-4-dehydrorhamnose reductase activity
IMCC19121_RS02185	COG1132	(ABC) transporter
IMCC19121_RS02190	COG1216	Glycosyl transferase, family 2
IMCC19121_RS02190	COG1442	glycosyl transferase family 8
IMCC19121_RS02200	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IMCC19121_RS02235	COG0009	L-threonylcarbamoyladenylate synthase
IMCC19121_RS02240	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IMCC19121_RS02245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC19121_RS02250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMCC19121_RS02255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC19121_RS02260	COG0463	Glycosyl transferase, family 2
IMCC19121_RS02265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC19121_RS02275	COG0028	Belongs to the TPP enzyme family
IMCC19121_RS02305	COG1595	DNA-templated transcription, initiation
IMCC19121_RS02360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC19121_RS02370	COG0667	Aldo Keto reductase
IMCC19121_RS02375	COG4702	Belongs to the UPF0303 family
IMCC19121_RS02380	COG1105	Belongs to the carbohydrate kinase PfkB family
IMCC19121_RS02390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMCC19121_RS02485	COG0456	acetyltransferase
IMCC19121_RS02490	COG0745	RESPONSE REGULATOR receiver
IMCC19121_RS02505	COG0735	belongs to the Fur family
IMCC19121_RS02510	COG0354	folic acid binding
IMCC19121_RS02515	COG4044	May play a role in the intracellular transport of hydrophobic ligands
IMCC19121_RS02525	COG0438	transferase activity, transferring glycosyl groups
IMCC19121_RS02535	COG0588	phosphoglycerate mutase activity
IMCC19121_RS02550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IMCC19121_RS02550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMCC19121_RS02555	COG0215	cysteine-tRNA ligase activity
IMCC19121_RS02560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC19121_RS02570	COG3250	beta-galactosidase activity
IMCC19121_RS02575	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMCC19121_RS02580	COG0494	nUDIX hydrolase
IMCC19121_RS02580	COG0406	alpha-ribazole phosphatase activity
IMCC19121_RS02585	COG0248	Ppx GppA phosphatase
IMCC19121_RS02605	COG1252	NADH dehydrogenase
IMCC19121_RS02610	COG0702	epimerase
IMCC19121_RS02615	COG0076	glutamate decarboxylase activity
IMCC19121_RS02625	COG0459	protein refolding
IMCC19121_RS02635	COG1278	Cold shock
IMCC19121_RS02645	COG2814	Major facilitator Superfamily
IMCC19121_RS02655	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMCC19121_RS02660	COG0259	pyridoxamine-phosphate oxidase activity
IMCC19121_RS02680	COG3833	ABC-type maltose transport systems, permease component
IMCC19121_RS02685	COG0366	Alpha amylase catalytic
IMCC19121_RS02695	COG2819	hydrolase of the alpha beta superfamily
IMCC19121_RS02700	COG0415	Belongs to the DNA photolyase family
IMCC19121_RS02705	COG5001	Diguanylate cyclase
IMCC19121_RS02705	COG3300	MHYT domain
IMCC19121_RS02715	COG0300	oxidoreductase activity
IMCC19121_RS02735	COG2409	Drug exporters of the RND superfamily
IMCC19121_RS02755	COG1960	acyl-CoA dehydrogenase activity
IMCC19121_RS02760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMCC19121_RS02790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC19121_RS02795	COG0084	hydrolase, TatD family'
IMCC19121_RS02800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMCC19121_RS02805	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMCC19121_RS02815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC19121_RS02820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMCC19121_RS02825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMCC19121_RS02830	COG0193	aminoacyl-tRNA hydrolase activity
IMCC19121_RS02835	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IMCC19121_RS02855	COG0148	phosphopyruvate hydratase activity
IMCC19121_RS02885	COG0477	Major facilitator Superfamily
IMCC19121_RS02905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMCC19121_RS02925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC19121_RS02930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IMCC19121_RS02940	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMCC19121_RS02940	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IMCC19121_RS02945	COG1722	exodeoxyribonuclease VII activity
IMCC19121_RS02950	COG1570	exodeoxyribonuclease VII activity
IMCC19121_RS02955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMCC19121_RS02970	COG0012	GTP binding
IMCC19121_RS02975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC19121_RS02985	COG2197	response regulator
IMCC19121_RS03000	COG1217	gtp-binding protein TYPA
IMCC19121_RS03005	COG1074	ATP-dependent DNA helicase activity
IMCC19121_RS03010	COG0210	DNA helicase
IMCC19121_RS03050	COG0516	GMP reductase activity
IMCC19121_RS03055	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC19121_RS03055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC19121_RS03060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMCC19121_RS03075	COG0045	succinate-CoA ligase (ADP-forming) activity
IMCC19121_RS03095	COG0138	bifunctional purine biosynthesis protein purh
IMCC19121_RS03100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMCC19121_RS03110	COG0039	L-malate dehydrogenase activity
IMCC19121_RS03115	COG0538	isocitrate dehydrogenase activity
IMCC19121_RS03120	COG3842	ATPase activity
IMCC19121_RS03125	COG1253	flavin adenine dinucleotide binding
IMCC19121_RS03130	COG0180	Tryptophanyl-tRNA synthetase
IMCC19121_RS03135	COG1744	ABC transporter substrate-binding protein PnrA-like
IMCC19121_RS03140	COG3845	ABC transporter
IMCC19121_RS03145	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMCC19121_RS03150	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC19121_RS03165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IMCC19121_RS03170	COG2124	cytochrome p450
IMCC19121_RS03175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC19121_RS03185	COG1012	belongs to the aldehyde dehydrogenase family
IMCC19121_RS03190	COG1012	belongs to the aldehyde dehydrogenase family
IMCC19121_RS03195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IMCC19121_RS03200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC19121_RS03210	COG4770	biotin carboxylase activity
IMCC19121_RS03215	COG0424	maF-like protein
IMCC19121_RS03225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC19121_RS03230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IMCC19121_RS03230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IMCC19121_RS03245	COG1832	CoA-binding protein
IMCC19121_RS03250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMCC19121_RS03255	COG1316	TRANSCRIPTIONal
IMCC19121_RS03280	COG2171	N-acyltransferase activity
IMCC19121_RS03285	COG1611	Belongs to the LOG family
IMCC19121_RS03295	COG1191	sigma factor activity
IMCC19121_RS03305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC19121_RS03315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC19121_RS03325	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC19121_RS03325	COG0489	protein tyrosine kinase activity
IMCC19121_RS03340	COG2095	MarC family integral membrane protein
IMCC19121_RS03345	COG0513	Belongs to the DEAD box helicase family
IMCC19121_RS03360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMCC19121_RS03370	COG0215	cysteine-tRNA ligase activity
IMCC19121_RS03380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IMCC19121_RS03390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMCC19121_RS03420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMCC19121_RS03425	COG0745	RESPONSE REGULATOR receiver
IMCC19121_RS03440	COG0653	protein targeting
IMCC19121_RS03480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC19121_RS03485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC19121_RS03515	COG0626	cystathionine gamma-synthase activity
IMCC19121_RS03535	COG0366	Alpha amylase catalytic
IMCC19121_RS03550	COG0745	RESPONSE REGULATOR receiver
IMCC19121_RS03555	COG2205	protein histidine kinase activity
IMCC19121_RS03570	COG0137	argininosuccinate synthase activity
IMCC19121_RS03575	COG0545	Peptidyl-prolyl cis-trans isomerase
IMCC19121_RS03585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMCC19121_RS03590	COG0730	response to heat
IMCC19121_RS03670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IMCC19121_RS03700	COG0366	Alpha amylase catalytic
IMCC19121_RS03720	COG0668	transmembrane transport
IMCC19121_RS03740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMCC19121_RS03745	COG0698	ribose 5-phosphate isomerase
IMCC19121_RS03770	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMCC19121_RS03775	COG0740	serine-type endopeptidase activity
IMCC19121_RS03780	COG0740	serine-type endopeptidase activity
IMCC19121_RS03790	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMCC19121_RS03795	COG0525	valine-tRNA ligase activity
IMCC19121_RS03800	COG0285	dihydrofolate synthase activity
IMCC19121_RS03810	COG0105	UTP biosynthetic process
IMCC19121_RS03815	COG1077	Cell shape determining protein MreB Mrl
IMCC19121_RS03835	COG0772	Belongs to the SEDS family
IMCC19121_RS03840	COG1530	ribonuclease E activity
IMCC19121_RS03845	COG0268	Binds directly to 16S ribosomal RNA
IMCC19121_RS03850	COG0481	GTPase activity
IMCC19121_RS03865	COG1420	regulation of RNA biosynthetic process
IMCC19121_RS03870	COG0484	heat shock protein binding
IMCC19121_RS03880	COG0537	adenosine 5'-monophosphoramidase activity
IMCC19121_RS03890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMCC19121_RS03900	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMCC19121_RS03905	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IMCC19121_RS03905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC19121_RS03935	COG1054	Belongs to the UPF0176 family
IMCC19121_RS03940	COG0646	methionine synthase
IMCC19121_RS03940	COG1410	methionine synthase
IMCC19121_RS03960	COG0746	molybdenum cofactor guanylyltransferase activity
IMCC19121_RS03970	COG0315	cyclic pyranopterin monophosphate synthase activity
IMCC19121_RS03975	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMCC19121_RS03985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMCC19121_RS04010	COG2086	electron transfer activity
IMCC19121_RS04015	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMCC19121_RS04020	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IMCC19121_RS04035	COG3383	formate dehydrogenase (NAD+) activity
IMCC19121_RS04065	COG5012	cobalamin binding
IMCC19121_RS04070	COG1414	Transcriptional regulator
IMCC19121_RS04075	COG5598	trimethylamine methyltransferase
IMCC19121_RS04080	COG1012	belongs to the aldehyde dehydrogenase family
IMCC19121_RS04085	COG0517	IMP dehydrogenase activity
IMCC19121_RS04085	COG4175	Glycine betaine
IMCC19121_RS04105	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMCC19121_RS04160	COG1960	acyl-CoA dehydrogenase activity
IMCC19121_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC19121_RS04245	COG3046	protein related to deoxyribodipyrimidine photolyase
IMCC19121_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC19121_RS04285	COG4266	Belongs to the allantoicase family
IMCC19121_RS04290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMCC19121_RS04295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IMCC19121_RS04310	COG1953	Uracil, thiamine, allantoin
IMCC19121_RS04315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMCC19121_RS04325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMCC19121_RS04330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMCC19121_RS04345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC19121_RS04345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC19121_RS04350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMCC19121_RS04385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC19121_RS04415	COG0488	(ABC) transporter
IMCC19121_RS04420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC19121_RS04425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC19121_RS04430	COG2313	pseudouridylate synthase activity
IMCC19121_RS04455	COG0335	large ribosomal subunit rRNA binding
IMCC19121_RS04460	COG0681	Belongs to the peptidase S26 family
IMCC19121_RS04465	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMCC19121_RS04480	COG0697	spore germination
IMCC19121_RS04485	COG0297	glycogen (starch) synthase activity
IMCC19121_RS04490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMCC19121_RS04495	COG1070	Carbohydrate kinase
IMCC19121_RS04500	COG0205	6-phosphofructokinase activity
IMCC19121_RS04505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IMCC19121_RS04510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMCC19121_RS04525	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IMCC19121_RS04530	COG2815	serine threonine protein kinase
IMCC19121_RS04530	COG0515	serine threonine protein kinase
IMCC19121_RS04565	COG0142	geranyltranstransferase activity
IMCC19121_RS04585	COG0463	Glycosyl transferase, family 2
IMCC19121_RS04665	COG1454	alcohol dehydrogenase
IMCC19121_RS04670	COG0659	secondary active sulfate transmembrane transporter activity
IMCC19121_RS04690	COG0587	DNA-directed DNA polymerase activity
IMCC19121_RS04695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMCC19121_RS04705	COG2001	Belongs to the MraZ family
IMCC19121_RS04710	COG0275	rRNA processing
IMCC19121_RS04720	COG0768	penicillin binding
IMCC19121_RS04725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMCC19121_RS04730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMCC19121_RS04735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC19121_RS04740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMCC19121_RS04745	COG0772	Belongs to the SEDS family
IMCC19121_RS04750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMCC19121_RS04755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMCC19121_RS04765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMCC19121_RS04770	COG1496	oxidoreductase activity
IMCC19121_RS04775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMCC19121_RS04780	COG1799	cell septum assembly
IMCC19121_RS04790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMCC19121_RS04800	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMCC19121_RS04810	COG0587	DNA-directed DNA polymerase activity
IMCC19121_RS04815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMCC19121_RS04820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMCC19121_RS04825	COG0131	Imidazoleglycerol-phosphate dehydratase
IMCC19121_RS04830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMCC19121_RS04835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMCC19121_RS04840	COG0107	imidazoleglycerol-phosphate synthase activity
IMCC19121_RS04845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMCC19121_RS04850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC19121_RS04855	COG0134	indole-3-glycerol-phosphate synthase activity
IMCC19121_RS04860	COG0133	tryptophan synthase activity
IMCC19121_RS04865	COG0159	tryptophan synthase activity
IMCC19121_RS04880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMCC19121_RS04890	COG0067	glutamate synthase
IMCC19121_RS04890	COG0069	glutamate synthase activity
IMCC19121_RS04890	COG0070	glutamate synthase
IMCC19121_RS04955	COG0411	ABC transporter
IMCC19121_RS04965	COG2050	protein possibly involved in aromatic compounds catabolism
IMCC19121_RS04980	COG0539	negative regulation of cytoplasmic translation
IMCC19121_RS04985	COG0237	dephospho-CoA kinase activity
IMCC19121_RS04990	COG0556	nucleotide-excision repair
IMCC19121_RS04995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMCC19121_RS05000	COG0322	excinuclease ABC activity
IMCC19121_RS05010	COG1660	Displays ATPase and GTPase activities
IMCC19121_RS05020	COG1481	regulation of sporulation
IMCC19121_RS05025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMCC19121_RS05030	COG0126	phosphoglycerate kinase activity
IMCC19121_RS05035	COG0149	triose-phosphate isomerase activity
IMCC19121_RS05040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC19121_RS05050	COG0166	Belongs to the GPI family
IMCC19121_RS05055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMCC19121_RS05080	COG0719	Fe-S assembly protein
IMCC19121_RS05085	COG2146	nitrite reductase [NAD(P)H] activity
IMCC19121_RS05090	COG0396	ATPase activity
IMCC19121_RS05095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMCC19121_RS05100	COG0822	iron-sulfur transferase activity
IMCC19121_RS05105	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC19121_RS05110	COG1132	(ABC) transporter
IMCC19121_RS05130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC19121_RS05135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMCC19121_RS05140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IMCC19121_RS05145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMCC19121_RS05150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC19121_RS05155	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMCC19121_RS05160	COG0072	phenylalanine-tRNA ligase activity
IMCC19121_RS05160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC19121_RS05165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMCC19121_RS05170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMCC19121_RS05175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMCC19121_RS05190	COG0165	Argininosuccinate lyase
IMCC19121_RS05195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMCC19121_RS05235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMCC19121_RS05240	COG0497	DNA recombination
IMCC19121_RS05245	COG0504	CTP synthase activity
IMCC19121_RS05250	COG0686	Belongs to the AlaDH PNT family
IMCC19121_RS05270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMCC19121_RS05275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMCC19121_RS05280	COG1187	pseudouridine synthase activity
IMCC19121_RS05295	COG1160	GTP binding
IMCC19121_RS05305	COG0509	glycine decarboxylation via glycine cleavage system
IMCC19121_RS05330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC19121_RS05330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC19121_RS05340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMCC19121_RS05355	COG0805	protein transport
IMCC19121_RS05370	COG2378	regulation of single-species biofilm formation
IMCC19121_RS05385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC19121_RS05395	COG0215	cysteine-tRNA ligase activity
IMCC19121_RS05415	COG0667	Aldo Keto reductase
IMCC19121_RS05420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC19121_RS05430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMCC19121_RS05435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMCC19121_RS05435	COG2755	lipolytic protein G-D-S-L family
IMCC19121_RS05440	COG1435	thymidine kinase activity
IMCC19121_RS05445	COG1064	alcohol dehydrogenase
IMCC19121_RS05455	COG2364	Membrane
IMCC19121_RS05460	COG2252	PERMEase
IMCC19121_RS05465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMCC19121_RS05470	COG1119	ATPase activity
IMCC19121_RS05475	COG0560	Phosphoserine phosphatase
IMCC19121_RS05475	COG3830	Belongs to the UPF0237 family
IMCC19121_RS05480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMCC19121_RS05485	COG0140	phosphoribosyl-ATP diphosphatase activity
IMCC19121_RS05490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMCC19121_RS05500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMCC19121_RS05505	COG0242	peptide deformylase activity
IMCC19121_RS05510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMCC19121_RS05515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMCC19121_RS05525	COG1758	RNA polymerase activity
IMCC19121_RS05530	COG0194	GDP metabolic process
IMCC19121_RS05535	COG0284	orotidine-5'-phosphate decarboxylase activity
IMCC19121_RS05540	COG0167	dihydroorotate dehydrogenase activity
IMCC19121_RS05550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMCC19121_RS05555	COG0505	Belongs to the CarA family
IMCC19121_RS05560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMCC19121_RS05565	COG0540	Belongs to the ATCase OTCase family
IMCC19121_RS05570	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMCC19121_RS05580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC19121_RS05585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMCC19121_RS05590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IMCC19121_RS05595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMCC19121_RS05600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMCC19121_RS05605	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMCC19121_RS05615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC19121_RS05625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMCC19121_RS05630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC19121_RS05640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMCC19121_RS05645	COG0124	histidyl-tRNA synthetase
IMCC19121_RS05650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC19121_RS05655	COG1196	nuclear chromosome segregation
IMCC19121_RS05660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMCC19121_RS05665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC19121_RS05670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC19121_RS05675	COG2255	four-way junction helicase activity
IMCC19121_RS05680	COG0632	four-way junction helicase activity
IMCC19121_RS05685	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IMCC19121_RS05690	COG0217	transcriptional regulatory protein
IMCC19121_RS05695	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMCC19121_RS05700	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMCC19121_RS05715	COG0438	transferase activity, transferring glycosyl groups
IMCC19121_RS05725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC19121_RS05740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMCC19121_RS05745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMCC19121_RS05750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC19121_RS05780	COG1914	H( )-stimulated, divalent metal cation uptake system
IMCC19121_RS05805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMCC19121_RS05815	COG1845	cytochrome c oxidase, subunit III
IMCC19121_RS05825	COG0723	plastoquinol--plastocyanin reductase activity
IMCC19121_RS05830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IMCC19121_RS05850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC19121_RS05855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMCC19121_RS05860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC19121_RS05875	COG0667	Aldo Keto reductase
IMCC19121_RS05890	COG3845	ABC transporter
IMCC19121_RS05900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC19121_RS05905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC19121_RS05910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMCC19121_RS05915	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC19121_RS05920	COG1090	epimerase
IMCC19121_RS05930	COG0673	inositol 2-dehydrogenase activity
IMCC19121_RS05935	COG2409	Drug exporters of the RND superfamily
IMCC19121_RS05940	COG0321	lipoyl(octanoyl) transferase activity
IMCC19121_RS05945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMCC19121_RS05970	COG0174	glutamine synthetase
IMCC19121_RS05995	COG1024	Enoyl-CoA hydratase
IMCC19121_RS06010	COG1260	myo-inositol-1-phosphate synthase
IMCC19121_RS06020	COG2233	PERMEase
IMCC19121_RS06025	COG1280	lysine exporter protein (LysE YggA)
IMCC19121_RS06035	COG0204	Acyl-transferase
IMCC19121_RS06045	COG0673	inositol 2-dehydrogenase activity
IMCC19121_RS06050	COG1940	carbohydrate kinase activity
IMCC19121_RS06070	COG2197	response regulator
IMCC19121_RS06075	COG0438	transferase activity, transferring glycosyl groups
IMCC19121_RS06080	COG0791	NLP P60 protein
IMCC19121_RS06105	COG0672	)-iron permease
IMCC19121_RS06110	COG0183	Belongs to the thiolase family
IMCC19121_RS06115	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC19121_RS06115	COG1024	Enoyl-CoA hydratase
IMCC19121_RS06120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMCC19121_RS06125	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMCC19121_RS06130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMCC19121_RS06135	COG0569	domain protein
IMCC19121_RS06150	COG0756	dUTP diphosphatase activity
IMCC19121_RS06170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMCC19121_RS06175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMCC19121_RS06180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMCC19121_RS06185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC19121_RS06195	COG0531	amino acid
IMCC19121_RS06205	COG1012	belongs to the aldehyde dehydrogenase family
IMCC19121_RS06210	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC19121_RS06210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC19121_RS06220	COG0336	Belongs to the RNA methyltransferase TrmD family
IMCC19121_RS06225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMCC19121_RS06230	COG1837	Belongs to the UPF0109 family
IMCC19121_RS06235	COG0228	four-way junction DNA binding
IMCC19121_RS06245	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IMCC19121_RS06270	COG0571	ribonuclease III activity
IMCC19121_RS06275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IMCC19121_RS06290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMCC19121_RS06305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IMCC19121_RS06310	COG4988	ABC transporter
IMCC19121_RS06315	COG1294	oxidase, subunit
IMCC19121_RS06320	COG1271	oxidase subunit
IMCC19121_RS06325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMCC19121_RS06340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IMCC19121_RS06345	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMCC19121_RS06350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMCC19121_RS06360	COG0776	regulation of translation
IMCC19121_RS06365	COG0066	3-isopropylmalate dehydratase activity
IMCC19121_RS06370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMCC19121_RS06385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMCC19121_RS06395	COG2267	carboxylic ester hydrolase activity
IMCC19121_RS06410	COG1396	sequence-specific DNA binding
IMCC19121_RS06415	COG1546	Belongs to the CinA family
IMCC19121_RS06415	COG1058	Belongs to the CinA family
IMCC19121_RS06425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC19121_RS06430	COG1426	Protein conserved in bacteria
IMCC19121_RS06430	COG1426	Protein conserved in bacteria
IMCC19121_RS06435	COG1674	ftsk spoiiie
IMCC19121_RS06445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC19121_RS06450	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IMCC19121_RS06470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMCC19121_RS06475	COG0612	Peptidase, M16
IMCC19121_RS06480	COG1185	polyribonucleotide nucleotidyltransferase activity
IMCC19121_RS06490	COG0196	riboflavin kinase activity
IMCC19121_RS06495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMCC19121_RS06500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMCC19121_RS06505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC19121_RS06505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC19121_RS06515	COG0779	Required for maturation of 30S ribosomal subunits
IMCC19121_RS06525	COG0442	prolyl-tRNA aminoacylation
IMCC19121_RS06530	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMCC19121_RS06535	COG0750	zinc metalloprotease
IMCC19121_RS06540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IMCC19121_RS06545	COG0010	Belongs to the arginase family
IMCC19121_RS06550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC19121_RS06555	COG1177	transmembrane transport
IMCC19121_RS06560	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC19121_RS06565	COG3842	ATPase activity
IMCC19121_RS06575	COG1012	belongs to the aldehyde dehydrogenase family
IMCC19121_RS06580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IMCC19121_RS06590	COG0233	cytoplasmic translational termination
IMCC19121_RS06595	COG0528	UMP kinase activity
IMCC19121_RS06600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMCC19121_RS06605	COG0052	Belongs to the universal ribosomal protein uS2 family
IMCC19121_RS06610	COG0463	Glycosyl transferase, family 2
IMCC19121_RS06615	COG4974	Belongs to the 'phage' integrase family
IMCC19121_RS06620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC19121_RS06625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMCC19121_RS06630	COG0473	3-isopropylmalate dehydrogenase activity
IMCC19121_RS06640	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMCC19121_RS06645	COG0440	acetolactate synthase activity
IMCC19121_RS06655	COG0129	dihydroxy-acid dehydratase activity
IMCC19121_RS06660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC19121_RS06665	COG0154	amidase activity
IMCC19121_RS06670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC19121_RS06675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMCC19121_RS06680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMCC19121_RS06685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMCC19121_RS06690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IMCC19121_RS06695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC19121_RS06705	COG1234	tRNA 3'-trailer cleavage
IMCC19121_RS06720	COG0495	leucyl-tRNA aminoacylation
IMCC19121_RS06740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMCC19121_RS06745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC19121_RS06750	COG0482	sulfurtransferase activity
IMCC19121_RS06760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMCC19121_RS06780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMCC19121_RS06785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC19121_RS06810	COG1278	Cold shock
IMCC19121_RS06830	COG2197	response regulator
IMCC19121_RS06845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMCC19121_RS06850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC19121_RS06870	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMCC19121_RS06895	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IMCC19121_RS06910	COG0423	glycine-tRNA ligase activity
IMCC19121_RS06930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC19121_RS06935	COG1381	Involved in DNA repair and RecF pathway recombination
IMCC19121_RS06940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC19121_RS06950	COG1045	serine acetyltransferase
IMCC19121_RS06960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC19121_RS06960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMCC19121_RS06965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IMCC19121_RS06985	COG0343	queuine tRNA-ribosyltransferase activity
IMCC19121_RS06990	COG2860	membrane
IMCC19121_RS07005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC19121_RS07015	COG0747	negative chemotaxis
IMCC19121_RS07040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMCC19121_RS07045	COG0581	inorganic phosphate transmembrane transporter activity
IMCC19121_RS07060	COG5002	protein histidine kinase activity
IMCC19121_RS07065	COG0745	RESPONSE REGULATOR receiver
IMCC19121_RS07070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMCC19121_RS07075	COG1982	Orn Lys Arg decarboxylase major
IMCC19121_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
IMCC19121_RS07105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IMCC19121_RS07110	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC19121_RS07130	COG2409	Drug exporters of the RND superfamily
IMCC19121_RS07175	COG1968	undecaprenyl-diphosphatase activity
IMCC19121_RS07180	COG2807	transmembrane transport
IMCC19121_RS07205	COG1476	TRANSCRIPTIONal
IMCC19121_RS07220	COG0384	phenazine biosynthesis protein PhzF
IMCC19121_RS07230	COG0010	Belongs to the arginase family
IMCC19121_RS07235	COG2986	histidine ammonia-lyase
IMCC19121_RS07240	COG1228	amidohydrolase
IMCC19121_RS07245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IMCC19121_RS07250	COG2258	MOSC domain
IMCC19121_RS07255	COG4608	Belongs to the ABC transporter superfamily
IMCC19121_RS07260	COG0444	Belongs to the ABC transporter superfamily
IMCC19121_RS07265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC19121_RS07275	COG4166	transmembrane transport
IMCC19121_RS07305	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IMCC19121_RS07310	COG0366	Alpha amylase catalytic
IMCC19121_RS07315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IMCC19121_RS07355	COG1131	(ABC) transporter
IMCC19121_RS07385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IMCC19121_RS07390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMCC19121_RS07395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMCC19121_RS07400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMCC19121_RS07405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC19121_RS07410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC19121_RS07415	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC19121_RS07420	COG0356	it plays a direct role in the translocation of protons across the membrane
IMCC19121_RS07435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC19121_RS07440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMCC19121_RS07455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMCC19121_RS07460	COG0254	rRNA binding
IMCC19121_RS07470	COG0083	homoserine kinase activity
IMCC19121_RS07475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMCC19121_RS07480	COG0460	homoserine dehydrogenase
IMCC19121_RS07490	COG0018	arginyl-trna synthetase
IMCC19121_RS07495	COG4213	ABC transporter substrate-binding protein
IMCC19121_RS07505	COG4214	carbohydrate transport
IMCC19121_RS07570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMCC19121_RS07575	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMCC19121_RS07580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMCC19121_RS07590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IMCC19121_RS07605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMCC19121_RS07625	COG1741	Belongs to the pirin family