locus-tag	class	description
IMCC26077_RS00005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMCC26077_RS00010	COG3409	Peptidoglycan-binding domain 1 protein
IMCC26077_RS00010	COG0793	Belongs to the peptidase S41A family
IMCC26077_RS00015	COG2177	Part of the ABC transporter FtsEX involved in
IMCC26077_RS00020	COG2884	Cell division ATP-binding protein ftsE
IMCC26077_RS00025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMCC26077_RS00080	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC26077_RS00080	COG0567	Dehydrogenase, E1 component
IMCC26077_RS00100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMCC26077_RS00110	COG1595	DNA-templated transcription, initiation
IMCC26077_RS00115	COG2135	peptidase activity
IMCC26077_RS00120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IMCC26077_RS00125	COG1162	GTPase activity
IMCC26077_RS00130	COG0483	inositol monophosphate 1-phosphatase activity
IMCC26077_RS00145	COG1615	UPF0182 protein
IMCC26077_RS00150	COG3480	Lon protease (S16) C-terminal proteolytic domain
IMCC26077_RS00175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IMCC26077_RS00185	COG0596	Alpha beta hydrolase
IMCC26077_RS00200	COG2816	NAD+ diphosphatase activity
IMCC26077_RS00225	COG1217	gtp-binding protein TYPA
IMCC26077_RS00235	COG0012	GTP binding
IMCC26077_RS00240	COG1322	Protein conserved in bacteria
IMCC26077_RS00250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMCC26077_RS00255	COG1570	exodeoxyribonuclease VII activity
IMCC26077_RS00260	COG1722	exodeoxyribonuclease VII activity
IMCC26077_RS00295	COG0459	protein refolding
IMCC26077_RS00310	COG0702	epimerase
IMCC26077_RS00315	COG1252	NADH dehydrogenase
IMCC26077_RS00325	COG3621	Patatin-like phospholipase
IMCC26077_RS00330	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IMCC26077_RS00350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IMCC26077_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS00360	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS00365	COG1175	transmembrane transport
IMCC26077_RS00375	COG1803	Methylglyoxal synthase
IMCC26077_RS00390	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS00405	COG0215	cysteine-tRNA ligase activity
IMCC26077_RS00410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMCC26077_RS00415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IMCC26077_RS00420	COG1329	Transcriptional regulator
IMCC26077_RS00430	COG0745	RESPONSE REGULATOR receiver
IMCC26077_RS00435	COG5002	protein histidine kinase activity
IMCC26077_RS00445	COG0588	phosphoglycerate mutase activity
IMCC26077_RS00455	COG0438	transferase activity, transferring glycosyl groups
IMCC26077_RS00470	COG4044	May play a role in the intracellular transport of hydrophobic ligands
IMCC26077_RS00500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMCC26077_RS00510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMCC26077_RS00515	COG1194	a g-specific adenine glycosylase
IMCC26077_RS00530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IMCC26077_RS00535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMCC26077_RS00540	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IMCC26077_RS00550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IMCC26077_RS00555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMCC26077_RS00560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMCC26077_RS00570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMCC26077_RS00575	COG0302	gtp cyclohydrolase
IMCC26077_RS00590	COG0037	tRNA processing
IMCC26077_RS00595	COG0791	NLP P60 protein
IMCC26077_RS00600	COG1525	nuclease
IMCC26077_RS00635	COG1063	alcohol dehydrogenase
IMCC26077_RS00640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMCC26077_RS00650	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IMCC26077_RS00675	COG0470	DNA polymerase III
IMCC26077_RS00685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMCC26077_RS00685	COG1754	DNA topoisomerase type I activity
IMCC26077_RS00690	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IMCC26077_RS00735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC26077_RS00785	COG3842	ATPase activity
IMCC26077_RS00820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMCC26077_RS00825	COG0598	Magnesium transport protein CorA
IMCC26077_RS00835	COG1408	metallophosphoesterase
IMCC26077_RS00895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMCC26077_RS00900	COG0582	viral genome integration into host DNA
IMCC26077_RS00905	COG1002	Type II restriction enzyme, methylase subunits
IMCC26077_RS01040	COG2897	thiosulfate sulfurtransferase activity
IMCC26077_RS01060	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS01065	COG1175	transmembrane transport
IMCC26077_RS01070	COG1653	transport
IMCC26077_RS01075	COG1414	Transcriptional regulator
IMCC26077_RS01080	COG3254	rhamnose metabolic process
IMCC26077_RS01090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26077_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS01100	COG4133	protoheme IX ABC transporter activity
IMCC26077_RS01105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMCC26077_RS01110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMCC26077_RS01125	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS01130	COG3254	rhamnose metabolic process
IMCC26077_RS01135	COG1129	ABC transporter
IMCC26077_RS01145	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMCC26077_RS01160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMCC26077_RS01180	COG0531	amino acid
IMCC26077_RS01195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMCC26077_RS01200	COG1192	Involved in chromosome partitioning
IMCC26077_RS01205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC26077_RS01230	COG2862	Uncharacterized protein family, UPF0114
IMCC26077_RS01245	COG1183	phosphatidylcholine synthase activity
IMCC26077_RS01255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC26077_RS01290	COG0516	GMP reductase activity
IMCC26077_RS01290	COG0517	IMP dehydrogenase activity
IMCC26077_RS01295	COG0513	Belongs to the DEAD box helicase family
IMCC26077_RS01330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMCC26077_RS01335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC26077_RS01335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMCC26077_RS01365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26077_RS01370	COG0776	regulation of translation
IMCC26077_RS01380	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26077_RS01385	COG0006	proline dipeptidase activity
IMCC26077_RS01395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMCC26077_RS01400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IMCC26077_RS01405	COG1053	succinate dehydrogenase
IMCC26077_RS01420	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS01430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMCC26077_RS01440	COG0631	protein serine/threonine phosphatase activity
IMCC26077_RS01445	COG0515	serine threonine protein kinase
IMCC26077_RS01480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC26077_RS01485	COG0187	DNA topoisomerase II activity
IMCC26077_RS01495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC26077_RS01500	COG0592	DNA-directed DNA polymerase activity
IMCC26077_RS01510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMCC26077_RS01520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IMCC26077_RS01530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMCC26077_RS01535	COG0706	membrane insertase activity
IMCC26077_RS01545	COG0357	Ribosomal RNA small subunit methyltransferase G
IMCC26077_RS01565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC26077_RS01575	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMCC26077_RS01575	COG3409	Peptidoglycan-binding domain 1 protein
IMCC26077_RS01580	COG3118	belongs to the thioredoxin family
IMCC26077_RS01585	COG0492	ferredoxin-NADP+ reductase activity
IMCC26077_RS01605	COG0617	tRNA 3'-terminal CCA addition
IMCC26077_RS01610	COG3046	protein related to deoxyribodipyrimidine photolyase
IMCC26077_RS01635	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS01645	COG0673	inositol 2-dehydrogenase activity
IMCC26077_RS01660	COG3254	rhamnose metabolic process
IMCC26077_RS01670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IMCC26077_RS01690	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS01695	COG1175	transmembrane transport
IMCC26077_RS01705	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS01710	COG1802	Transcriptional regulator
IMCC26077_RS01725	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS01750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMCC26077_RS01770	COG0360	Binds together with S18 to 16S ribosomal RNA
IMCC26077_RS01780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMCC26077_RS01785	COG0359	binds to the 23S rRNA
IMCC26077_RS01790	COG0305	Participates in initiation and elongation during chromosome replication
IMCC26077_RS01800	COG1960	acyl-CoA dehydrogenase activity
IMCC26077_RS01805	COG1704	LemA family
IMCC26077_RS01810	COG0501	Belongs to the peptidase M48B family
IMCC26077_RS01820	COG0717	Belongs to the dCTP deaminase family
IMCC26077_RS01825	COG2205	protein histidine kinase activity
IMCC26077_RS01830	COG0745	RESPONSE REGULATOR receiver
IMCC26077_RS01840	COG1183	phosphatidylcholine synthase activity
IMCC26077_RS01845	COG0247	lactate metabolic process
IMCC26077_RS01845	COG2181	nitrate reductase activity
IMCC26077_RS01850	COG0443	Heat shock 70 kDa protein
IMCC26077_RS01855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMCC26077_RS01860	COG0484	heat shock protein binding
IMCC26077_RS01865	COG0789	Transcriptional regulator
IMCC26077_RS01870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMCC26077_RS01880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMCC26077_RS01885	COG0151	Belongs to the GarS family
IMCC26077_RS01890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMCC26077_RS01895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMCC26077_RS01900	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC26077_RS01905	COG0047	phosphoribosylformylglycinamidine synthase activity
IMCC26077_RS01910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC26077_RS01915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC26077_RS01920	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS01935	COG0129	dihydroxy-acid dehydratase activity
IMCC26077_RS01940	COG1414	Transcriptional regulator
IMCC26077_RS01955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMCC26077_RS01980	COG1175	transmembrane transport
IMCC26077_RS01985	COG3833	ABC-type maltose transport systems, permease component
IMCC26077_RS01990	COG0673	inositol 2-dehydrogenase activity
IMCC26077_RS02000	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS02015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IMCC26077_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS02045	COG1414	Transcriptional regulator
IMCC26077_RS02070	COG0667	Aldo Keto reductase
IMCC26077_RS02080	COG1902	pentaerythritol trinitrate reductase activity
IMCC26077_RS02110	COG0009	L-threonylcarbamoyladenylate synthase
IMCC26077_RS02155	COG0673	inositol 2-dehydrogenase activity
IMCC26077_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS02180	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IMCC26077_RS02195	COG1105	Belongs to the carbohydrate kinase PfkB family
IMCC26077_RS02205	COG4702	Belongs to the UPF0303 family
IMCC26077_RS02210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMCC26077_RS02255	COG3384	dioxygenase
IMCC26077_RS02270	COG0745	RESPONSE REGULATOR receiver
IMCC26077_RS02295	COG1477	protein flavinylation
IMCC26077_RS02305	COG2897	thiosulfate sulfurtransferase activity
IMCC26077_RS02320	COG0354	folic acid binding
IMCC26077_RS02330	COG1061	Type III restriction enzyme res subunit
IMCC26077_RS02335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC26077_RS02345	COG0406	alpha-ribazole phosphatase activity
IMCC26077_RS02350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC26077_RS02355	COG0785	Cytochrome C biogenesis protein
IMCC26077_RS02360	COG1333	cytochrome c biogenesis protein
IMCC26077_RS02365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC26077_RS02385	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMCC26077_RS02390	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS02395	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IMCC26077_RS02400	COG1169	isochorismate synthase
IMCC26077_RS02410	COG2226	methyltransferase
IMCC26077_RS02420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26077_RS02430	COG0649	NAD binding
IMCC26077_RS02440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IMCC26077_RS02445	COG1034	ATP synthesis coupled electron transport
IMCC26077_RS02450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMCC26077_RS02455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26077_RS02460	COG0839	Belongs to the complex I subunit 6 family
IMCC26077_RS02470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMCC26077_RS02485	COG0142	geranyltranstransferase activity
IMCC26077_RS02490	COG2962	Rard protein
IMCC26077_RS02515	COG1175	transmembrane transport
IMCC26077_RS02520	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS02525	COG1104	cysteine desulfurase activity
IMCC26077_RS02535	COG0022	dehydrogenase e1 component
IMCC26077_RS02555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMCC26077_RS02575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMCC26077_RS02580	COG0259	pyridoxamine-phosphate oxidase activity
IMCC26077_RS02590	COG0415	Belongs to the DNA photolyase family
IMCC26077_RS02595	COG5310	Homospermidine synthase
IMCC26077_RS02600	COG3706	GGDEF domain
IMCC26077_RS02615	COG4221	oxidoreductase activity
IMCC26077_RS02635	COG0788	formyltetrahydrofolate deformylase activity
IMCC26077_RS02640	COG2409	Drug exporters of the RND superfamily
IMCC26077_RS02665	COG1960	acyl-CoA dehydrogenase activity
IMCC26077_RS02670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMCC26077_RS02675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMCC26077_RS02705	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC26077_RS02710	COG0084	hydrolase, TatD family'
IMCC26077_RS02715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMCC26077_RS02720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMCC26077_RS02730	COG1846	Transcriptional regulator
IMCC26077_RS02745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC26077_RS02750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMCC26077_RS02755	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMCC26077_RS02760	COG0193	aminoacyl-tRNA hydrolase activity
IMCC26077_RS02765	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IMCC26077_RS02830	COG2814	Major facilitator Superfamily
IMCC26077_RS02845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMCC26077_RS02865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC26077_RS02870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IMCC26077_RS02885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMCC26077_RS02890	COG2030	dehydratase
IMCC26077_RS02895	COG2030	dehydratase
IMCC26077_RS02905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMCC26077_RS02910	COG0436	Aminotransferase
IMCC26077_RS02920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC26077_RS02930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMCC26077_RS02935	COG0081	regulation of translation
IMCC26077_RS02940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMCC26077_RS02945	COG0222	ribosome binding
IMCC26077_RS02950	COG0085	RNA polymerase activity
IMCC26077_RS02955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMCC26077_RS02960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMCC26077_RS02965	COG0049	tRNA binding
IMCC26077_RS02970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMCC26077_RS02975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC26077_RS02980	COG0051	transcription antitermination factor activity, RNA binding
IMCC26077_RS02985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMCC26077_RS02990	COG0088	Forms part of the polypeptide exit tunnel
IMCC26077_RS02995	COG0089	rRNA binding
IMCC26077_RS03000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMCC26077_RS03005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IMCC26077_RS03010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMCC26077_RS03015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMCC26077_RS03020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMCC26077_RS03025	COG0255	Belongs to the universal ribosomal protein uL29 family
IMCC26077_RS03030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMCC26077_RS03035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMCC26077_RS03040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMCC26077_RS03045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMCC26077_RS03050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMCC26077_RS03055	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMCC26077_RS03060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMCC26077_RS03065	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMCC26077_RS03070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMCC26077_RS03075	COG1841	ribosomal large subunit assembly
IMCC26077_RS03080	COG0200	Binds to the 23S rRNA
IMCC26077_RS03090	COG0563	adenylate kinase activity
IMCC26077_RS03100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMCC26077_RS03105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IMCC26077_RS03110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMCC26077_RS03115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMCC26077_RS03120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMCC26077_RS03130	COG0203	ribosomal protein L17
IMCC26077_RS03135	COG0101	tRNA pseudouridine synthase activity
IMCC26077_RS03140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMCC26077_RS03145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMCC26077_RS03155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMCC26077_RS03160	COG0671	phosphoesterase, PA-phosphatase related
IMCC26077_RS03165	COG0736	holo-[acyl-carrier-protein] synthase activity
IMCC26077_RS03170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMCC26077_RS03180	COG0410	ABC transporter
IMCC26077_RS03210	COG0802	atpase or kinase
IMCC26077_RS03220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC26077_RS03225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMCC26077_RS03230	COG0459	protein refolding
IMCC26077_RS03250	COG0516	GMP reductase activity
IMCC26077_RS03255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC26077_RS03255	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC26077_RS03270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC26077_RS03275	COG0045	succinate-CoA ligase (ADP-forming) activity
IMCC26077_RS03295	COG0138	bifunctional purine biosynthesis protein purh
IMCC26077_RS03300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMCC26077_RS03320	COG3842	ATPase activity
IMCC26077_RS03325	COG1253	flavin adenine dinucleotide binding
IMCC26077_RS03330	COG0180	Tryptophanyl-tRNA synthetase
IMCC26077_RS03335	COG1686	Belongs to the peptidase S11 family
IMCC26077_RS03340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC26077_RS03340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IMCC26077_RS03345	COG4770	biotin carboxylase activity
IMCC26077_RS03350	COG0424	maF-like protein
IMCC26077_RS03355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC26077_RS03360	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IMCC26077_RS03360	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IMCC26077_RS03370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMCC26077_RS03375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMCC26077_RS03380	COG1316	TRANSCRIPTIONal
IMCC26077_RS03405	COG2171	N-acyltransferase activity
IMCC26077_RS03410	COG1611	Belongs to the LOG family
IMCC26077_RS03415	COG2814	Major facilitator Superfamily
IMCC26077_RS03435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IMCC26077_RS03440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC26077_RS03450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC26077_RS03455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMCC26077_RS03470	COG2239	Acts as a magnesium transporter
IMCC26077_RS03485	COG2095	MarC family integral membrane protein
IMCC26077_RS03525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMCC26077_RS03535	COG2720	vancomycin resistance protein
IMCC26077_RS03540	COG0215	cysteine-tRNA ligase activity
IMCC26077_RS03560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMCC26077_RS03595	COG1482	cell wall glycoprotein biosynthetic process
IMCC26077_RS03600	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMCC26077_RS03605	COG0745	RESPONSE REGULATOR receiver
IMCC26077_RS03610	COG5002	protein histidine kinase activity
IMCC26077_RS03610	COG5000	phosphorelay sensor kinase activity
IMCC26077_RS03620	COG0653	protein targeting
IMCC26077_RS03660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC26077_RS03690	COG0277	FAD linked oxidase domain protein
IMCC26077_RS03720	COG0109	protoheme IX farnesyltransferase activity
IMCC26077_RS03730	COG0137	argininosuccinate synthase activity
IMCC26077_RS03735	COG0477	Major facilitator Superfamily
IMCC26077_RS03740	COG3588	fructose-bisphosphate aldolase
IMCC26077_RS03760	COG1054	Belongs to the UPF0176 family
IMCC26077_RS03820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMCC26077_RS03840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMCC26077_RS03845	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IMCC26077_RS03870	COG0668	transmembrane transport
IMCC26077_RS03875	COG1505	serine-type exopeptidase activity
IMCC26077_RS03900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMCC26077_RS03905	COG0698	ribose 5-phosphate isomerase
IMCC26077_RS03920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMCC26077_RS03925	COG1312	Catalyzes the dehydration of D-mannonate
IMCC26077_RS03945	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMCC26077_RS03950	COG0740	serine-type endopeptidase activity
IMCC26077_RS03955	COG0740	serine-type endopeptidase activity
IMCC26077_RS03960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMCC26077_RS03965	COG0525	valine-tRNA ligase activity
IMCC26077_RS03970	COG0285	dihydrofolate synthase activity
IMCC26077_RS03980	COG0105	UTP biosynthetic process
IMCC26077_RS03985	COG1077	Cell shape determining protein MreB Mrl
IMCC26077_RS04000	COG0768	penicillin binding
IMCC26077_RS04005	COG0772	Belongs to the SEDS family
IMCC26077_RS04010	COG1530	ribonuclease E activity
IMCC26077_RS04015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC26077_RS04020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IMCC26077_RS04025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMCC26077_RS04030	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMCC26077_RS04040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMCC26077_RS04045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC26077_RS04050	COG0154	amidase activity
IMCC26077_RS04055	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC26077_RS04065	COG0129	dihydroxy-acid dehydratase activity
IMCC26077_RS04075	COG0440	acetolactate synthase activity
IMCC26077_RS04080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMCC26077_RS04085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC26077_RS04090	COG0473	3-isopropylmalate dehydrogenase activity
IMCC26077_RS04095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMCC26077_RS04100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC26077_RS04110	COG4974	Belongs to the 'phage' integrase family
IMCC26077_RS04120	COG0052	Belongs to the universal ribosomal protein uS2 family
IMCC26077_RS04125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMCC26077_RS04130	COG0528	UMP kinase activity
IMCC26077_RS04135	COG0233	cytoplasmic translational termination
IMCC26077_RS04140	COG0575	Belongs to the CDS family
IMCC26077_RS04145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IMCC26077_RS04150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC26077_RS04160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC26077_RS04180	COG3842	ATPase activity
IMCC26077_RS04185	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC26077_RS04195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMCC26077_RS04200	COG0010	Belongs to the arginase family
IMCC26077_RS04210	COG1070	Carbohydrate kinase
IMCC26077_RS04215	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IMCC26077_RS04220	COG0750	zinc metalloprotease
IMCC26077_RS04225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMCC26077_RS04235	COG0442	prolyl-tRNA aminoacylation
IMCC26077_RS04240	COG0779	Required for maturation of 30S ribosomal subunits
IMCC26077_RS04250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC26077_RS04250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC26077_RS04255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMCC26077_RS04260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMCC26077_RS04270	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMCC26077_RS04275	COG1185	polyribonucleotide nucleotidyltransferase activity
IMCC26077_RS04280	COG0612	Peptidase, M16
IMCC26077_RS04285	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMCC26077_RS04305	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IMCC26077_RS04310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC26077_RS04320	COG1674	ftsk spoiiie
IMCC26077_RS04330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC26077_RS04340	COG1546	Belongs to the CinA family
IMCC26077_RS04340	COG1058	Belongs to the CinA family
IMCC26077_RS04345	COG1396	sequence-specific DNA binding
IMCC26077_RS04360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMCC26077_RS04365	COG2137	regulation of response to DNA damage stimulus
IMCC26077_RS04375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC26077_RS04380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMCC26077_RS04390	COG1129	ABC transporter
IMCC26077_RS04400	COG3254	rhamnose metabolic process
IMCC26077_RS04405	COG0673	inositol 2-dehydrogenase activity
IMCC26077_RS04410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMCC26077_RS04415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMCC26077_RS04420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMCC26077_RS04425	COG1388	LysM domain
IMCC26077_RS04430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMCC26077_RS04435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMCC26077_RS04440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMCC26077_RS04480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMCC26077_RS04485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC26077_RS04505	COG0187	DNA topoisomerase II activity
IMCC26077_RS04510	COG2814	Major facilitator Superfamily
IMCC26077_RS04515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC26077_RS04550	COG0756	dUTP diphosphatase activity
IMCC26077_RS04565	COG0569	domain protein
IMCC26077_RS04570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMCC26077_RS04575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMCC26077_RS04580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMCC26077_RS04585	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC26077_RS04585	COG1024	Enoyl-CoA hydratase
IMCC26077_RS04590	COG0183	Belongs to the thiolase family
IMCC26077_RS04595	COG0672	)-iron permease
IMCC26077_RS04615	COG0791	NLP P60 protein
IMCC26077_RS04615	COG3883	PFAM NLP P60 protein
IMCC26077_RS04620	COG0438	transferase activity, transferring glycosyl groups
IMCC26077_RS04625	COG2197	response regulator
IMCC26077_RS04630	COG4585	Histidine kinase
IMCC26077_RS04645	COG1940	carbohydrate kinase activity
IMCC26077_RS04660	COG2233	PERMEase
IMCC26077_RS04670	COG1260	myo-inositol-1-phosphate synthase
IMCC26077_RS04680	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS04685	COG1122	ATPase activity
IMCC26077_RS04700	COG0310	cobalt ion transport
IMCC26077_RS04705	COG0659	secondary active sulfate transmembrane transporter activity
IMCC26077_RS04715	COG1904	glucuronate isomerase
IMCC26077_RS04720	COG0246	Mannitol dehydrogenase
IMCC26077_RS04725	COG2721	sulfolactate sulfo-lyase activity
IMCC26077_RS04740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC26077_RS04745	COG0765	amino acid transport
IMCC26077_RS04750	COG1126	abc transporter atp-binding protein
IMCC26077_RS04765	COG0174	glutamine synthetase
IMCC26077_RS04785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMCC26077_RS04790	COG0321	lipoyl(octanoyl) transferase activity
IMCC26077_RS04795	COG2409	Drug exporters of the RND superfamily
IMCC26077_RS04800	COG0673	inositol 2-dehydrogenase activity
IMCC26077_RS04815	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC26077_RS04820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMCC26077_RS04825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC26077_RS04830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC26077_RS04840	COG3845	ABC transporter
IMCC26077_RS04855	COG0667	Aldo Keto reductase
IMCC26077_RS04865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMCC26077_RS04875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26077_RS04880	COG0425	Belongs to the sulfur carrier protein TusA family
IMCC26077_RS04885	COG1104	cysteine desulfurase activity
IMCC26077_RS04890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMCC26077_RS04895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC26077_RS04905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IMCC26077_RS04910	COG0723	plastoquinol--plastocyanin reductase activity
IMCC26077_RS04920	COG1845	cytochrome c oxidase, subunit III
IMCC26077_RS04930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMCC26077_RS04980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC26077_RS04980	COG0512	Glutamine amidotransferase of anthranilate synthase
IMCC26077_RS04995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMCC26077_RS05010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC26077_RS05015	COG1560	Kdo2-lipid A biosynthetic process
IMCC26077_RS05020	COG0438	transferase activity, transferring glycosyl groups
IMCC26077_RS05030	COG1470	cell adhesion involved in biofilm formation
IMCC26077_RS05035	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMCC26077_RS05040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMCC26077_RS05045	COG0217	transcriptional regulatory protein
IMCC26077_RS05050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IMCC26077_RS05055	COG0632	four-way junction helicase activity
IMCC26077_RS05060	COG2255	four-way junction helicase activity
IMCC26077_RS05065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC26077_RS05070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC26077_RS05075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMCC26077_RS05080	COG1196	nuclear chromosome segregation
IMCC26077_RS05090	COG0124	histidyl-tRNA synthetase
IMCC26077_RS05095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMCC26077_RS05105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMCC26077_RS05120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC26077_RS05125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMCC26077_RS05135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC26077_RS05145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMCC26077_RS05150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMCC26077_RS05155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMCC26077_RS05160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IMCC26077_RS05165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMCC26077_RS05170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC26077_RS05180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMCC26077_RS05185	COG0540	Belongs to the ATCase OTCase family
IMCC26077_RS05190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMCC26077_RS05195	COG0505	Belongs to the CarA family
IMCC26077_RS05200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMCC26077_RS05205	COG0543	2 iron, 2 sulfur cluster binding
IMCC26077_RS05210	COG0167	dihydroorotate dehydrogenase activity
IMCC26077_RS05215	COG0284	orotidine-5'-phosphate decarboxylase activity
IMCC26077_RS05225	COG0194	GDP metabolic process
IMCC26077_RS05230	COG1758	RNA polymerase activity
IMCC26077_RS05240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMCC26077_RS05250	COG0242	peptide deformylase activity
IMCC26077_RS05255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMCC26077_RS05265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMCC26077_RS05270	COG0140	phosphoribosyl-ATP diphosphatase activity
IMCC26077_RS05275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMCC26077_RS05280	COG0560	Phosphoserine phosphatase
IMCC26077_RS05280	COG3830	Belongs to the UPF0237 family
IMCC26077_RS05285	COG1119	ATPase activity
IMCC26077_RS05290	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMCC26077_RS05295	COG2252	PERMEase
IMCC26077_RS05300	COG2364	Membrane
IMCC26077_RS05305	COG1968	undecaprenyl-diphosphatase activity
IMCC26077_RS05315	COG1064	alcohol dehydrogenase
IMCC26077_RS05320	COG0488	(ABC) transporter
IMCC26077_RS05325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMCC26077_RS05335	COG0604	alcohol dehydrogenase
IMCC26077_RS05345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC26077_RS05355	COG0667	Aldo Keto reductase
IMCC26077_RS05375	COG0215	cysteine-tRNA ligase activity
IMCC26077_RS05385	COG1410	methionine synthase
IMCC26077_RS05385	COG0646	methionine synthase
IMCC26077_RS05390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC26077_RS05420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMCC26077_RS05425	COG0805	protein transport
IMCC26077_RS05435	COG4581	dead DEAH box helicase
IMCC26077_RS05440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMCC26077_RS05445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IMCC26077_RS05450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IMCC26077_RS05455	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC26077_RS05455	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC26077_RS05480	COG1716	ATPase activity
IMCC26077_RS05485	COG0509	glycine decarboxylation via glycine cleavage system
IMCC26077_RS05505	COG0287	Prephenate dehydrogenase
IMCC26077_RS05520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMCC26077_RS05525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMCC26077_RS05545	COG0686	Belongs to the AlaDH PNT family
IMCC26077_RS05550	COG0504	CTP synthase activity
IMCC26077_RS05555	COG0497	DNA recombination
IMCC26077_RS05560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMCC26077_RS05600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMCC26077_RS05605	COG0165	Argininosuccinate lyase
IMCC26077_RS05610	COG1438	arginine binding
IMCC26077_RS05615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMCC26077_RS05620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMCC26077_RS05625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMCC26077_RS05630	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMCC26077_RS05635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC26077_RS05635	COG0072	phenylalanine-tRNA ligase activity
IMCC26077_RS05640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMCC26077_RS05645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC26077_RS05650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMCC26077_RS05655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IMCC26077_RS05660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMCC26077_RS05665	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC26077_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS05685	COG1132	(ABC) transporter
IMCC26077_RS05690	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC26077_RS05705	COG0396	ATPase activity
IMCC26077_RS05715	COG0719	Fe-S assembly protein
IMCC26077_RS05730	COG1612	heme a metabolic process
IMCC26077_RS05740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMCC26077_RS05745	COG0166	Belongs to the GPI family
IMCC26077_RS05755	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC26077_RS05760	COG0149	triose-phosphate isomerase activity
IMCC26077_RS05765	COG0126	phosphoglycerate kinase activity
IMCC26077_RS05770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMCC26077_RS05775	COG1481	regulation of sporulation
IMCC26077_RS05780	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IMCC26077_RS05785	COG1660	Displays ATPase and GTPase activities
IMCC26077_RS05790	COG0322	excinuclease ABC activity
IMCC26077_RS05800	COG0556	nucleotide-excision repair
IMCC26077_RS05805	COG0237	dephospho-CoA kinase activity
IMCC26077_RS05820	COG2050	protein possibly involved in aromatic compounds catabolism
IMCC26077_RS05870	COG0069	glutamate synthase activity
IMCC26077_RS05870	COG0067	glutamate synthase
IMCC26077_RS05870	COG0070	glutamate synthase
IMCC26077_RS05880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMCC26077_RS05895	COG0159	tryptophan synthase activity
IMCC26077_RS05900	COG0133	tryptophan synthase activity
IMCC26077_RS05905	COG0134	indole-3-glycerol-phosphate synthase activity
IMCC26077_RS05920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC26077_RS05925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMCC26077_RS05930	COG0107	imidazoleglycerol-phosphate synthase activity
IMCC26077_RS05935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMCC26077_RS05940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMCC26077_RS05945	COG0131	Imidazoleglycerol-phosphate dehydratase
IMCC26077_RS05955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMCC26077_RS05960	COG0587	DNA-directed DNA polymerase activity
IMCC26077_RS05970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMCC26077_RS05980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMCC26077_RS05990	COG1799	cell septum assembly
IMCC26077_RS05995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMCC26077_RS06005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMCC26077_RS06015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMCC26077_RS06030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMCC26077_RS06035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26077_RS06040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMCC26077_RS06045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMCC26077_RS06050	COG0768	penicillin binding
IMCC26077_RS06060	COG0275	rRNA processing
IMCC26077_RS06065	COG2001	Belongs to the MraZ family
IMCC26077_RS06070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMCC26077_RS06085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMCC26077_RS06090	COG0587	DNA-directed DNA polymerase activity
IMCC26077_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS06160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMCC26077_RS06165	COG0142	geranyltranstransferase activity
IMCC26077_RS06195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMCC26077_RS06195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMCC26077_RS06200	COG2815	serine threonine protein kinase
IMCC26077_RS06200	COG0515	serine threonine protein kinase
IMCC26077_RS06205	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IMCC26077_RS06215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMCC26077_RS06215	COG2169	Transcriptional regulator
IMCC26077_RS06220	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IMCC26077_RS06225	COG0205	6-phosphofructokinase activity
IMCC26077_RS06250	COG0792	nuclease activity
IMCC26077_RS06255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMCC26077_RS06265	COG0335	large ribosomal subunit rRNA binding
IMCC26077_RS06270	COG0336	Belongs to the RNA methyltransferase TrmD family
IMCC26077_RS06275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMCC26077_RS06280	COG1837	Belongs to the UPF0109 family
IMCC26077_RS06285	COG0228	four-way junction DNA binding
IMCC26077_RS06290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMCC26077_RS06305	COG0552	protein localization to endoplasmic reticulum
IMCC26077_RS06310	COG1196	nuclear chromosome segregation
IMCC26077_RS06320	COG0571	ribonuclease III activity
IMCC26077_RS06325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IMCC26077_RS06330	COG1399	metal-binding, possibly nucleic acid-binding protein
IMCC26077_RS06340	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMCC26077_RS06345	COG0742	ribosomal rna small subunit methyltransferase
IMCC26077_RS06355	COG1461	Dihydroxyacetone kinase
IMCC26077_RS06360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMCC26077_RS06365	COG0545	Peptidyl-prolyl cis-trans isomerase
IMCC26077_RS06380	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMCC26077_RS06385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMCC26077_RS06395	COG0776	regulation of translation
IMCC26077_RS06400	COG0066	3-isopropylmalate dehydratase activity
IMCC26077_RS06405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMCC26077_RS06425	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IMCC26077_RS06425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC26077_RS06430	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMCC26077_RS06445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMCC26077_RS06455	COG0537	adenosine 5'-monophosphoramidase activity
IMCC26077_RS06460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMCC26077_RS06465	COG0484	heat shock protein binding
IMCC26077_RS06470	COG1420	regulation of RNA biosynthetic process
IMCC26077_RS06490	COG0481	GTPase activity
IMCC26077_RS06495	COG0268	Binds directly to 16S ribosomal RNA
IMCC26077_RS06515	COG1307	EDD domain protein, DegV family
IMCC26077_RS06520	COG0495	leucyl-tRNA aminoacylation
IMCC26077_RS06540	COG0799	negative regulation of ribosome biogenesis
IMCC26077_RS06545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMCC26077_RS06550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC26077_RS06555	COG0482	sulfurtransferase activity
IMCC26077_RS06565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMCC26077_RS06575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMCC26077_RS06580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMCC26077_RS06585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC26077_RS06590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMCC26077_RS06605	COG1278	Cold shock
IMCC26077_RS06610	COG0248	Ppx GppA phosphatase
IMCC26077_RS06615	COG0406	alpha-ribazole phosphatase activity
IMCC26077_RS06615	COG0494	nUDIX hydrolase
IMCC26077_RS06620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMCC26077_RS06640	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS06645	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS06650	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS06675	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS06680	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS06715	COG1312	Catalyzes the dehydration of D-mannonate
IMCC26077_RS06725	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS06730	COG1175	transmembrane transport
IMCC26077_RS06740	COG1063	alcohol dehydrogenase
IMCC26077_RS06745	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS06750	COG0246	Mannitol dehydrogenase
IMCC26077_RS06760	COG2814	Major facilitator Superfamily
IMCC26077_RS06765	COG5002	protein histidine kinase activity
IMCC26077_RS06780	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS06800	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS06810	COG3608	succinylglutamate desuccinylase aspartoacylase
IMCC26077_RS06845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC26077_RS06850	COG0444	Belongs to the ABC transporter superfamily
IMCC26077_RS06855	COG4608	Belongs to the ABC transporter superfamily
IMCC26077_RS06865	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS06890	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS06910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IMCC26077_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS06930	COG0129	dihydroxy-acid dehydratase activity
IMCC26077_RS06950	COG0574	Belongs to the PEP-utilizing enzyme family
IMCC26077_RS06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMCC26077_RS06965	COG0800	Aldolase
IMCC26077_RS06980	COG0277	FAD linked oxidase domain protein
IMCC26077_RS06985	COG0247	lactate metabolic process
IMCC26077_RS06995	COG0395	ABC-type sugar transport system, permease component
IMCC26077_RS07000	COG1175	transmembrane transport
IMCC26077_RS07010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IMCC26077_RS07010	COG0473	3-isopropylmalate dehydrogenase activity
IMCC26077_RS07015	COG0148	phosphopyruvate hydratase activity
IMCC26077_RS07025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC26077_RS07035	COG0358	DNA primase activity
IMCC26077_RS07040	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IMCC26077_RS07055	COG0423	glycine-tRNA ligase activity
IMCC26077_RS07070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC26077_RS07075	COG1381	Involved in DNA repair and RecF pathway recombination
IMCC26077_RS07080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC26077_RS07095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMCC26077_RS07095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC26077_RS07100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IMCC26077_RS07120	COG4608	Belongs to the ABC transporter superfamily
IMCC26077_RS07125	COG0444	Belongs to the ABC transporter superfamily
IMCC26077_RS07135	COG0747	negative chemotaxis
IMCC26077_RS07140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC26077_RS07145	COG0343	queuine tRNA-ribosyltransferase activity
IMCC26077_RS07155	COG1872	DUF167
IMCC26077_RS07175	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IMCC26077_RS07180	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS07190	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC26077_RS07195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMCC26077_RS07200	COG0022	dehydrogenase e1 component
IMCC26077_RS07200	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC26077_RS07205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMCC26077_RS07210	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS07215	COG3618	amidohydrolase
IMCC26077_RS07225	COG2124	cytochrome p450
IMCC26077_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS07250	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS07275	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS07280	COG2860	membrane
IMCC26077_RS07285	COG1082	Xylose isomerase domain protein TIM barrel
IMCC26077_RS07295	COG1063	alcohol dehydrogenase
IMCC26077_RS07305	COG0488	(ABC) transporter
IMCC26077_RS07315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IMCC26077_RS07315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMCC26077_RS07330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMCC26077_RS07390	COG0789	Transcriptional regulator
IMCC26077_RS07400	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26077_RS07410	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26077_RS07430	COG2311	Membrane
IMCC26077_RS07435	COG2076	Multidrug Resistance protein
IMCC26077_RS07445	COG1476	TRANSCRIPTIONal
IMCC26077_RS07475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC26077_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS07500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMCC26077_RS07540	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IMCC26077_RS07555	COG1703	isobutyryl-CoA mutase activity
IMCC26077_RS07565	COG0628	permease
IMCC26077_RS07590	COG1131	(ABC) transporter
IMCC26077_RS07615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMCC26077_RS07630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IMCC26077_RS07635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMCC26077_RS07640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMCC26077_RS07645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMCC26077_RS07650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC26077_RS07655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC26077_RS07660	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC26077_RS07665	COG0356	it plays a direct role in the translocation of protons across the membrane
IMCC26077_RS07680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26077_RS07685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMCC26077_RS07695	COG2890	protein-(glutamine-N5) methyltransferase activity
IMCC26077_RS07700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMCC26077_RS07705	COG0254	rRNA binding
IMCC26077_RS07715	COG0083	homoserine kinase activity
IMCC26077_RS07720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMCC26077_RS07725	COG0460	homoserine dehydrogenase
IMCC26077_RS07735	COG0018	arginyl-trna synthetase
IMCC26077_RS07750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMCC26077_RS07755	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMCC26077_RS07760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMCC26077_RS07785	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC26077_RS07785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC26077_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26077_RS07795	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26077_RS07820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IMCC26077_RS07835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMCC26077_RS07855	COG1741	Belongs to the pirin family