locus-tag	class	description
IMCC26103_RS00005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMCC26103_RS00010	COG2177	Part of the ABC transporter FtsEX involved in
IMCC26103_RS00015	COG2884	Cell division ATP-binding protein ftsE
IMCC26103_RS00020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IMCC26103_RS00060	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS00065	COG0567	Dehydrogenase, E1 component
IMCC26103_RS00065	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC26103_RS00090	COG1595	DNA-templated transcription, initiation
IMCC26103_RS00095	COG2135	peptidase activity
IMCC26103_RS00100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IMCC26103_RS00105	COG1162	GTPase activity
IMCC26103_RS00110	COG0483	inositol monophosphate 1-phosphatase activity
IMCC26103_RS00130	COG1615	UPF0182 protein
IMCC26103_RS00135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMCC26103_RS00195	COG0210	DNA helicase
IMCC26103_RS00205	COG1217	gtp-binding protein TYPA
IMCC26103_RS00210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMCC26103_RS00215	COG0012	GTP binding
IMCC26103_RS00220	COG1322	Protein conserved in bacteria
IMCC26103_RS00230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMCC26103_RS00235	COG1570	exodeoxyribonuclease VII activity
IMCC26103_RS00240	COG1722	exodeoxyribonuclease VII activity
IMCC26103_RS00255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IMCC26103_RS00260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC26103_RS00280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMCC26103_RS00295	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS00300	COG1063	alcohol dehydrogenase
IMCC26103_RS00305	COG0129	dihydroxy-acid dehydratase activity
IMCC26103_RS00345	COG1063	alcohol dehydrogenase
IMCC26103_RS00380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMCC26103_RS00445	COG0148	phosphopyruvate hydratase activity
IMCC26103_RS00465	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IMCC26103_RS00470	COG0193	aminoacyl-tRNA hydrolase activity
IMCC26103_RS00475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMCC26103_RS00480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMCC26103_RS00485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMCC26103_RS00500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMCC26103_RS00505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMCC26103_RS00510	COG0084	hydrolase, TatD family'
IMCC26103_RS00515	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC26103_RS00535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMCC26103_RS00545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMCC26103_RS00550	COG1960	acyl-CoA dehydrogenase activity
IMCC26103_RS00570	COG2409	Drug exporters of the RND superfamily
IMCC26103_RS00585	COG0300	oxidoreductase activity
IMCC26103_RS00605	COG0415	Belongs to the DNA photolyase family
IMCC26103_RS00615	COG0259	pyridoxamine-phosphate oxidase activity
IMCC26103_RS00620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMCC26103_RS00640	COG1278	Cold shock
IMCC26103_RS00650	COG0459	protein refolding
IMCC26103_RS00665	COG0702	epimerase
IMCC26103_RS00670	COG1252	NADH dehydrogenase
IMCC26103_RS00675	COG0596	Alpha beta hydrolase
IMCC26103_RS00690	COG0248	Ppx GppA phosphatase
IMCC26103_RS00695	COG0406	alpha-ribazole phosphatase activity
IMCC26103_RS00695	COG0494	nUDIX hydrolase
IMCC26103_RS00700	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMCC26103_RS00715	COG0215	cysteine-tRNA ligase activity
IMCC26103_RS00720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IMCC26103_RS00720	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMCC26103_RS00725	COG1329	Transcriptional regulator
IMCC26103_RS00735	COG0588	phosphoglycerate mutase activity
IMCC26103_RS00745	COG0438	transferase activity, transferring glycosyl groups
IMCC26103_RS00755	COG4044	May play a role in the intracellular transport of hydrophobic ligands
IMCC26103_RS00760	COG0354	folic acid binding
IMCC26103_RS00765	COG0735	belongs to the Fur family
IMCC26103_RS00775	COG2897	thiosulfate sulfurtransferase activity
IMCC26103_RS00790	COG0745	RESPONSE REGULATOR receiver
IMCC26103_RS00795	COG0456	acetyltransferase
IMCC26103_RS00805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMCC26103_RS00820	COG4702	Belongs to the UPF0303 family
IMCC26103_RS00830	COG0667	Aldo Keto reductase
IMCC26103_RS00845	COG1017	nitric oxide dioxygenase activity
IMCC26103_RS00845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMCC26103_RS00850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26103_RS00890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMCC26103_RS00905	COG1132	(ABC) transporter
IMCC26103_RS00915	COG0438	transferase activity, transferring glycosyl groups
IMCC26103_RS00930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26103_RS00935	COG0438	transferase activity, transferring glycosyl groups
IMCC26103_RS00945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMCC26103_RS01015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26103_RS01030	COG3959	Transketolase, thiamine diphosphate binding domain
IMCC26103_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS01070	COG1083	cytidylyl-transferase
IMCC26103_RS01075	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IMCC26103_RS01085	COG2089	acid synthase
IMCC26103_RS01090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IMCC26103_RS01110	COG0470	DNA polymerase III
IMCC26103_RS01115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMCC26103_RS01145	COG1754	DNA topoisomerase type I activity
IMCC26103_RS01145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMCC26103_RS01150	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IMCC26103_RS01155	COG0586	Pfam SNARE associated Golgi protein
IMCC26103_RS01160	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMCC26103_RS01165	COG0789	Transcriptional regulator
IMCC26103_RS01170	COG0484	heat shock protein binding
IMCC26103_RS01175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMCC26103_RS01180	COG0443	Heat shock 70 kDa protein
IMCC26103_RS01185	COG0247	lactate metabolic process
IMCC26103_RS01185	COG2181	nitrate reductase activity
IMCC26103_RS01190	COG0705	Rhomboid family
IMCC26103_RS01210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC26103_RS01215	COG0187	DNA topoisomerase II activity
IMCC26103_RS01225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMCC26103_RS01230	COG0592	DNA-directed DNA polymerase activity
IMCC26103_RS01235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMCC26103_RS01240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IMCC26103_RS01250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMCC26103_RS01255	COG0706	membrane insertase activity
IMCC26103_RS01265	COG0357	Ribosomal RNA small subunit methyltransferase G
IMCC26103_RS01270	COG1192	Involved in chromosome partitioning
IMCC26103_RS01275	COG1475	DNA binding
IMCC26103_RS01280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMCC26103_RS01285	COG3409	Peptidoglycan-binding domain 1 protein
IMCC26103_RS01285	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMCC26103_RS01290	COG3118	belongs to the thioredoxin family
IMCC26103_RS01295	COG0492	ferredoxin-NADP+ reductase activity
IMCC26103_RS01315	COG0617	tRNA 3'-terminal CCA addition
IMCC26103_RS01330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMCC26103_RS01340	COG0360	Binds together with S18 to 16S ribosomal RNA
IMCC26103_RS01350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMCC26103_RS01355	COG0359	binds to the 23S rRNA
IMCC26103_RS01360	COG0305	Participates in initiation and elongation during chromosome replication
IMCC26103_RS01370	COG1960	acyl-CoA dehydrogenase activity
IMCC26103_RS01375	COG0717	Belongs to the dCTP deaminase family
IMCC26103_RS01380	COG1704	LemA family
IMCC26103_RS01385	COG0501	Belongs to the peptidase M48B family
IMCC26103_RS01390	COG2205	protein histidine kinase activity
IMCC26103_RS01395	COG0745	RESPONSE REGULATOR receiver
IMCC26103_RS01410	COG0515	serine threonine protein kinase
IMCC26103_RS01425	COG0077	Prephenate dehydratase
IMCC26103_RS01430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMCC26103_RS01435	COG0561	phosphatase activity
IMCC26103_RS01450	COG1053	succinate dehydrogenase
IMCC26103_RS01460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMCC26103_RS01470	COG0006	proline dipeptidase activity
IMCC26103_RS01475	COG3959	Transketolase, thiamine diphosphate binding domain
IMCC26103_RS01480	COG3958	Transketolase
IMCC26103_RS01485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC26103_RS01490	COG1082	Xylose isomerase domain protein TIM barrel
IMCC26103_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS01535	COG4221	oxidoreductase activity
IMCC26103_RS01540	COG0673	inositol 2-dehydrogenase activity
IMCC26103_RS01545	COG1082	Xylose isomerase domain protein TIM barrel
IMCC26103_RS01550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC26103_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS01630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26103_RS01635	COG1869	D-ribose catabolic process
IMCC26103_RS01645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMCC26103_RS01650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMCC26103_RS01660	COG3483	tryptophan 2,3-dioxygenase activity
IMCC26103_RS01665	COG3844	kynureninase activity
IMCC26103_RS01670	COG0488	(ABC) transporter
IMCC26103_RS01675	COG2862	Uncharacterized protein family, UPF0114
IMCC26103_RS01685	COG0586	Pfam SNARE associated Golgi protein
IMCC26103_RS01695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMCC26103_RS01705	COG0590	tRNA wobble adenosine to inosine editing
IMCC26103_RS01710	COG0531	amino acid
IMCC26103_RS01735	COG1476	TRANSCRIPTIONal
IMCC26103_RS01755	COG2197	response regulator
IMCC26103_RS01780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMCC26103_RS01795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMCC26103_RS01800	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IMCC26103_RS01805	COG1408	metallophosphoesterase
IMCC26103_RS01810	COG1610	YqeY-like protein
IMCC26103_RS01840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC26103_RS01850	COG0191	fructose-bisphosphate aldolase activity
IMCC26103_RS01855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMCC26103_RS01860	COG0151	Belongs to the GarS family
IMCC26103_RS01865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMCC26103_RS01870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMCC26103_RS01875	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC26103_RS01880	COG0047	phosphoribosylformylglycinamidine synthase activity
IMCC26103_RS01885	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMCC26103_RS01920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26103_RS01955	COG0009	L-threonylcarbamoyladenylate synthase
IMCC26103_RS01985	COG1845	cytochrome c oxidase, subunit III
IMCC26103_RS01985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC26103_RS02000	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IMCC26103_RS02025	COG2027	D-alanyl-D-alanine carboxypeptidase
IMCC26103_RS02040	COG0109	protoheme IX farnesyltransferase activity
IMCC26103_RS02060	COG0791	NLP P60 protein
IMCC26103_RS02065	COG0037	tRNA processing
IMCC26103_RS02080	COG0302	gtp cyclohydrolase
IMCC26103_RS02090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMCC26103_RS02095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMCC26103_RS02100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMCC26103_RS02105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IMCC26103_RS02115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IMCC26103_RS02120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMCC26103_RS02125	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IMCC26103_RS02135	COG0277	FAD linked oxidase domain protein
IMCC26103_RS02140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMCC26103_RS02150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMCC26103_RS02195	COG0406	alpha-ribazole phosphatase activity
IMCC26103_RS02200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMCC26103_RS02205	COG0785	Cytochrome C biogenesis protein
IMCC26103_RS02210	COG1333	cytochrome c biogenesis protein
IMCC26103_RS02215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMCC26103_RS02230	COG0318	PFAM AMP-dependent synthetase and ligase
IMCC26103_RS02240	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26103_RS02245	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IMCC26103_RS02250	COG1169	isochorismate synthase
IMCC26103_RS02260	COG2226	methyltransferase
IMCC26103_RS02270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26103_RS02275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26103_RS02280	COG0649	NAD binding
IMCC26103_RS02290	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IMCC26103_RS02295	COG1034	ATP synthesis coupled electron transport
IMCC26103_RS02300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IMCC26103_RS02305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMCC26103_RS02310	COG0839	Belongs to the complex I subunit 6 family
IMCC26103_RS02335	COG0142	geranyltranstransferase activity
IMCC26103_RS02345	COG1666	GTP binding
IMCC26103_RS02380	COG1175	transmembrane transport
IMCC26103_RS02385	COG0395	ABC-type sugar transport system, permease component
IMCC26103_RS02390	COG2186	Transcriptional regulator
IMCC26103_RS02395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26103_RS02400	COG3684	Belongs to the aldolase LacD family
IMCC26103_RS02405	COG0673	inositol 2-dehydrogenase activity
IMCC26103_RS02415	COG2721	sulfolactate sulfo-lyase activity
IMCC26103_RS02420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC26103_RS02425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IMCC26103_RS02430	COG2855	membrane
IMCC26103_RS02435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMCC26103_RS02445	COG1126	abc transporter atp-binding protein
IMCC26103_RS02450	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IMCC26103_RS02450	COG0235	Class ii aldolase
IMCC26103_RS02455	COG3347	Dehydrogenase
IMCC26103_RS02455	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS02485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMCC26103_RS02490	COG2030	dehydratase
IMCC26103_RS02505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMCC26103_RS02515	COG0436	Aminotransferase
IMCC26103_RS02535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMCC26103_RS02540	COG0081	regulation of translation
IMCC26103_RS02545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMCC26103_RS02550	COG0222	ribosome binding
IMCC26103_RS02560	COG0085	RNA polymerase activity
IMCC26103_RS02565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMCC26103_RS02570	COG0813	purine-nucleoside phosphorylase activity
IMCC26103_RS02575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMCC26103_RS02580	COG0049	tRNA binding
IMCC26103_RS02585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMCC26103_RS02590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMCC26103_RS02595	COG0051	transcription antitermination factor activity, RNA binding
IMCC26103_RS02600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMCC26103_RS02605	COG0088	Forms part of the polypeptide exit tunnel
IMCC26103_RS02610	COG0089	rRNA binding
IMCC26103_RS02625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMCC26103_RS02630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMCC26103_RS02635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMCC26103_RS02640	COG0255	Belongs to the universal ribosomal protein uL29 family
IMCC26103_RS02645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMCC26103_RS02650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMCC26103_RS02660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMCC26103_RS02665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMCC26103_RS02670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMCC26103_RS02675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMCC26103_RS02680	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMCC26103_RS02685	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMCC26103_RS02690	COG1841	ribosomal large subunit assembly
IMCC26103_RS02695	COG0200	Binds to the 23S rRNA
IMCC26103_RS02705	COG0563	adenylate kinase activity
IMCC26103_RS02710	COG0024	Methionine aminopeptidase
IMCC26103_RS02735	COG1595	DNA-templated transcription, initiation
IMCC26103_RS02765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IMCC26103_RS02770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IMCC26103_RS02775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMCC26103_RS02780	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMCC26103_RS02785	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMCC26103_RS02790	COG0202	RNA polymerase activity
IMCC26103_RS02795	COG0203	ribosomal protein L17
IMCC26103_RS02800	COG0101	tRNA pseudouridine synthase activity
IMCC26103_RS02810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMCC26103_RS02815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMCC26103_RS02820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC26103_RS02825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMCC26103_RS02835	COG0736	holo-[acyl-carrier-protein] synthase activity
IMCC26103_RS02840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMCC26103_RS02845	COG0411	ABC transporter
IMCC26103_RS02880	COG0456	acetyltransferase
IMCC26103_RS02880	COG1214	PFAM Peptidase M22, glycoprotease
IMCC26103_RS02890	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMCC26103_RS02895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMCC26103_RS02900	COG0459	protein refolding
IMCC26103_RS02925	COG0516	GMP reductase activity
IMCC26103_RS02930	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC26103_RS02930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC26103_RS02950	COG0045	succinate-CoA ligase (ADP-forming) activity
IMCC26103_RS02975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMCC26103_RS03000	COG2160	L-arabinose isomerase activity
IMCC26103_RS03010	COG1175	transmembrane transport
IMCC26103_RS03015	COG0395	ABC-type sugar transport system, permease component
IMCC26103_RS03025	COG0148	phosphopyruvate hydratase activity
IMCC26103_RS03030	COG3842	ATPase activity
IMCC26103_RS03035	COG1253	flavin adenine dinucleotide binding
IMCC26103_RS03040	COG0180	Tryptophanyl-tRNA synthetase
IMCC26103_RS03060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IMCC26103_RS03065	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26103_RS03070	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26103_RS03080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC26103_RS03090	COG4770	biotin carboxylase activity
IMCC26103_RS03095	COG0424	maF-like protein
IMCC26103_RS03105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMCC26103_RS03120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMCC26103_RS03125	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMCC26103_RS03130	COG1316	TRANSCRIPTIONal
IMCC26103_RS03135	COG1216	Glycosyl transferase, family 2
IMCC26103_RS03155	COG2171	N-acyltransferase activity
IMCC26103_RS03160	COG1611	Belongs to the LOG family
IMCC26103_RS03180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC26103_RS03190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC26103_RS03200	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC26103_RS03200	COG0489	protein tyrosine kinase activity
IMCC26103_RS03210	COG2239	Acts as a magnesium transporter
IMCC26103_RS03225	COG2095	MarC family integral membrane protein
IMCC26103_RS03240	COG0513	Belongs to the DEAD box helicase family
IMCC26103_RS03260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMCC26103_RS03270	COG0215	cysteine-tRNA ligase activity
IMCC26103_RS03315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMCC26103_RS03320	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMCC26103_RS03325	COG0745	RESPONSE REGULATOR receiver
IMCC26103_RS03330	COG5002	protein histidine kinase activity
IMCC26103_RS03340	COG0653	protein targeting
IMCC26103_RS03380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC26103_RS03385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMCC26103_RS03430	COG0745	RESPONSE REGULATOR receiver
IMCC26103_RS03450	COG0137	argininosuccinate synthase activity
IMCC26103_RS03455	COG0545	Peptidyl-prolyl cis-trans isomerase
IMCC26103_RS03465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMCC26103_RS03510	COG0489	protein tyrosine kinase activity
IMCC26103_RS03540	COG0110	maltose O-acetyltransferase activity
IMCC26103_RS03605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IMCC26103_RS03645	COG0668	transmembrane transport
IMCC26103_RS03665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMCC26103_RS03670	COG0698	ribose 5-phosphate isomerase
IMCC26103_RS03685	COG3842	ATPase activity
IMCC26103_RS03690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IMCC26103_RS03695	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC26103_RS03700	COG1177	transmembrane transport
IMCC26103_RS03715	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMCC26103_RS03725	COG0740	serine-type endopeptidase activity
IMCC26103_RS03730	COG0740	serine-type endopeptidase activity
IMCC26103_RS03740	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMCC26103_RS03745	COG0525	valine-tRNA ligase activity
IMCC26103_RS03750	COG0285	dihydrofolate synthase activity
IMCC26103_RS03760	COG0105	UTP biosynthetic process
IMCC26103_RS03765	COG1077	Cell shape determining protein MreB Mrl
IMCC26103_RS03785	COG0772	Belongs to the SEDS family
IMCC26103_RS03790	COG1530	ribonuclease E activity
IMCC26103_RS03795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMCC26103_RS03800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IMCC26103_RS03805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMCC26103_RS03810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMCC26103_RS03815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMCC26103_RS03820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC26103_RS03825	COG0154	amidase activity
IMCC26103_RS03830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMCC26103_RS03835	COG0129	dihydroxy-acid dehydratase activity
IMCC26103_RS03850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMCC26103_RS03855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC26103_RS03860	COG0473	3-isopropylmalate dehydrogenase activity
IMCC26103_RS03865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMCC26103_RS03870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC26103_RS03875	COG4974	Belongs to the 'phage' integrase family
IMCC26103_RS03880	COG0052	Belongs to the universal ribosomal protein uS2 family
IMCC26103_RS03885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMCC26103_RS03890	COG0528	UMP kinase activity
IMCC26103_RS03895	COG0233	cytoplasmic translational termination
IMCC26103_RS03905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IMCC26103_RS03925	COG3842	ATPase activity
IMCC26103_RS03930	COG1176	ABC-type spermidine putrescine transport system, permease component I
IMCC26103_RS03955	COG0750	zinc metalloprotease
IMCC26103_RS03960	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMCC26103_RS03965	COG0442	prolyl-tRNA aminoacylation
IMCC26103_RS03975	COG0779	Required for maturation of 30S ribosomal subunits
IMCC26103_RS03990	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC26103_RS03990	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMCC26103_RS03995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMCC26103_RS04000	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMCC26103_RS04015	COG1185	polyribonucleotide nucleotidyltransferase activity
IMCC26103_RS04020	COG0612	Peptidase, M16
IMCC26103_RS04025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMCC26103_RS04045	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
IMCC26103_RS04050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMCC26103_RS04060	COG1674	ftsk spoiiie
IMCC26103_RS04070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC26103_RS04080	COG1546	Belongs to the CinA family
IMCC26103_RS04080	COG1058	Belongs to the CinA family
IMCC26103_RS04085	COG1396	sequence-specific DNA binding
IMCC26103_RS04100	COG3022	response to hydroperoxide
IMCC26103_RS04105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMCC26103_RS04110	COG2137	regulation of response to DNA damage stimulus
IMCC26103_RS04120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMCC26103_RS04125	COG0066	3-isopropylmalate dehydratase activity
IMCC26103_RS04130	COG0776	regulation of translation
IMCC26103_RS04140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMCC26103_RS04145	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMCC26103_RS04160	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IMCC26103_RS04170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMCC26103_RS04175	COG1271	oxidase subunit
IMCC26103_RS04180	COG1294	oxidase, subunit
IMCC26103_RS04185	COG4988	ABC transporter
IMCC26103_RS04190	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IMCC26103_RS04200	COG0742	ribosomal rna small subunit methyltransferase
IMCC26103_RS04205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMCC26103_RS04220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IMCC26103_RS04225	COG0571	ribonuclease III activity
IMCC26103_RS04250	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IMCC26103_RS04260	COG0228	four-way junction DNA binding
IMCC26103_RS04265	COG1837	Belongs to the UPF0109 family
IMCC26103_RS04270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMCC26103_RS04275	COG0336	Belongs to the RNA methyltransferase TrmD family
IMCC26103_RS04285	COG0519	Catalyzes the synthesis of GMP from XMP
IMCC26103_RS04285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMCC26103_RS04290	COG1454	alcohol dehydrogenase
IMCC26103_RS04295	COG1012	belongs to the aldehyde dehydrogenase family
IMCC26103_RS04320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMCC26103_RS04325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMCC26103_RS04330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMCC26103_RS04335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMCC26103_RS04355	COG0756	dUTP diphosphatase activity
IMCC26103_RS04370	COG0569	domain protein
IMCC26103_RS04375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMCC26103_RS04380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMCC26103_RS04385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMCC26103_RS04390	COG1024	Enoyl-CoA hydratase
IMCC26103_RS04390	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMCC26103_RS04395	COG0183	Belongs to the thiolase family
IMCC26103_RS04400	COG0672	)-iron permease
IMCC26103_RS04430	COG0791	NLP P60 protein
IMCC26103_RS04435	COG0438	transferase activity, transferring glycosyl groups
IMCC26103_RS04440	COG2197	response regulator
IMCC26103_RS04460	COG1940	carbohydrate kinase activity
IMCC26103_RS04475	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IMCC26103_RS04480	COG1280	lysine exporter protein (LysE YggA)
IMCC26103_RS04485	COG2233	PERMEase
IMCC26103_RS04500	COG1024	Enoyl-CoA hydratase
IMCC26103_RS04505	COG0300	oxidoreductase activity
IMCC26103_RS04525	COG0174	glutamine synthetase
IMCC26103_RS04545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMCC26103_RS04550	COG0321	lipoyl(octanoyl) transferase activity
IMCC26103_RS04555	COG2409	Drug exporters of the RND superfamily
IMCC26103_RS04570	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMCC26103_RS04575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMCC26103_RS04580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMCC26103_RS04585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMCC26103_RS04595	COG3845	ABC transporter
IMCC26103_RS04610	COG0667	Aldo Keto reductase
IMCC26103_RS04620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMCC26103_RS04630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26103_RS04640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMCC26103_RS04645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMCC26103_RS04660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IMCC26103_RS04665	COG0723	plastoquinol--plastocyanin reductase activity
IMCC26103_RS04670	COG2010	Cytochrome c
IMCC26103_RS04675	COG1845	cytochrome c oxidase, subunit III
IMCC26103_RS04685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMCC26103_RS04700	COG0154	amidase activity
IMCC26103_RS04720	COG4213	ABC transporter substrate-binding protein
IMCC26103_RS04730	COG4214	carbohydrate transport
IMCC26103_RS04770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMCC26103_RS04785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC26103_RS04790	COG1560	Kdo2-lipid A biosynthetic process
IMCC26103_RS04795	COG0438	transferase activity, transferring glycosyl groups
IMCC26103_RS04810	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMCC26103_RS04820	COG0217	transcriptional regulatory protein
IMCC26103_RS04825	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IMCC26103_RS04830	COG0632	four-way junction helicase activity
IMCC26103_RS04835	COG2255	four-way junction helicase activity
IMCC26103_RS04840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC26103_RS04845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMCC26103_RS04850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMCC26103_RS04855	COG1196	nuclear chromosome segregation
IMCC26103_RS04860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMCC26103_RS04865	COG0124	histidyl-tRNA synthetase
IMCC26103_RS04870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMCC26103_RS04880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMCC26103_RS04885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMCC26103_RS04895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMCC26103_RS04905	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMCC26103_RS04910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMCC26103_RS04915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMCC26103_RS04920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IMCC26103_RS04925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMCC26103_RS04930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMCC26103_RS04940	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMCC26103_RS04945	COG0540	Belongs to the ATCase OTCase family
IMCC26103_RS04950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMCC26103_RS04955	COG0505	Belongs to the CarA family
IMCC26103_RS04960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMCC26103_RS04965	COG0543	2 iron, 2 sulfur cluster binding
IMCC26103_RS04970	COG0167	dihydroorotate dehydrogenase activity
IMCC26103_RS04975	COG0284	orotidine-5'-phosphate decarboxylase activity
IMCC26103_RS04980	COG0194	GDP metabolic process
IMCC26103_RS04985	COG1758	RNA polymerase activity
IMCC26103_RS04995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMCC26103_RS05005	COG0242	peptide deformylase activity
IMCC26103_RS05010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMCC26103_RS05020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMCC26103_RS05030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMCC26103_RS05035	COG3830	Belongs to the UPF0237 family
IMCC26103_RS05035	COG0560	Phosphoserine phosphatase
IMCC26103_RS05040	COG1119	ATPase activity
IMCC26103_RS05050	COG2252	PERMEase
IMCC26103_RS05055	COG2364	Membrane
IMCC26103_RS05065	COG1064	alcohol dehydrogenase
IMCC26103_RS05070	COG1435	thymidine kinase activity
IMCC26103_RS05075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMCC26103_RS05075	COG2755	lipolytic protein G-D-S-L family
IMCC26103_RS05080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMCC26103_RS05090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMCC26103_RS05095	COG0667	Aldo Keto reductase
IMCC26103_RS05115	COG0215	cysteine-tRNA ligase activity
IMCC26103_RS05125	COG1410	methionine synthase
IMCC26103_RS05125	COG0646	methionine synthase
IMCC26103_RS05130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC26103_RS05150	COG2378	regulation of single-species biofilm formation
IMCC26103_RS05160	COG0805	protein transport
IMCC26103_RS05175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMCC26103_RS05190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC26103_RS05190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMCC26103_RS05210	COG1716	ATPase activity
IMCC26103_RS05215	COG0509	glycine decarboxylation via glycine cleavage system
IMCC26103_RS05225	COG1160	GTP binding
IMCC26103_RS05245	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMCC26103_RS05250	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMCC26103_RS05270	COG0686	Belongs to the AlaDH PNT family
IMCC26103_RS05275	COG0504	CTP synthase activity
IMCC26103_RS05280	COG0497	DNA recombination
IMCC26103_RS05285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMCC26103_RS05325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMCC26103_RS05330	COG0165	Argininosuccinate lyase
IMCC26103_RS05335	COG1438	arginine binding
IMCC26103_RS05345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMCC26103_RS05350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMCC26103_RS05355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMCC26103_RS05360	COG0072	phenylalanine-tRNA ligase activity
IMCC26103_RS05360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMCC26103_RS05365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMCC26103_RS05370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMCC26103_RS05375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMCC26103_RS05380	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IMCC26103_RS05385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMCC26103_RS05390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMCC26103_RS05410	COG1132	(ABC) transporter
IMCC26103_RS05415	COG2151	metal-sulfur cluster biosynthetic enzyme
IMCC26103_RS05420	COG0822	iron-sulfur transferase activity
IMCC26103_RS05425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMCC26103_RS05430	COG0396	ATPase activity
IMCC26103_RS05435	COG2146	nitrite reductase [NAD(P)H] activity
IMCC26103_RS05440	COG0719	Fe-S assembly protein
IMCC26103_RS05460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMCC26103_RS05465	COG0166	Belongs to the GPI family
IMCC26103_RS05475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMCC26103_RS05480	COG0149	triose-phosphate isomerase activity
IMCC26103_RS05485	COG0126	phosphoglycerate kinase activity
IMCC26103_RS05490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMCC26103_RS05495	COG1481	regulation of sporulation
IMCC26103_RS05500	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IMCC26103_RS05505	COG1660	Displays ATPase and GTPase activities
IMCC26103_RS05510	COG0322	excinuclease ABC activity
IMCC26103_RS05515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMCC26103_RS05520	COG0556	nucleotide-excision repair
IMCC26103_RS05525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IMCC26103_RS05525	COG0237	dephospho-CoA kinase activity
IMCC26103_RS05530	COG0539	negative regulation of cytoplasmic translation
IMCC26103_RS05545	COG2050	protein possibly involved in aromatic compounds catabolism
IMCC26103_RS05595	COG0070	glutamate synthase
IMCC26103_RS05595	COG0069	glutamate synthase activity
IMCC26103_RS05595	COG0067	glutamate synthase
IMCC26103_RS05605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMCC26103_RS05620	COG0159	tryptophan synthase activity
IMCC26103_RS05625	COG0133	tryptophan synthase activity
IMCC26103_RS05630	COG0134	indole-3-glycerol-phosphate synthase activity
IMCC26103_RS05635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMCC26103_RS05640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMCC26103_RS05645	COG0107	imidazoleglycerol-phosphate synthase activity
IMCC26103_RS05650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMCC26103_RS05660	COG0131	Imidazoleglycerol-phosphate dehydratase
IMCC26103_RS05665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMCC26103_RS05670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMCC26103_RS05675	COG0587	DNA-directed DNA polymerase activity
IMCC26103_RS05685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMCC26103_RS05695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMCC26103_RS05705	COG1799	cell septum assembly
IMCC26103_RS05710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMCC26103_RS05715	COG1496	oxidoreductase activity
IMCC26103_RS05720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMCC26103_RS05730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMCC26103_RS05735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMCC26103_RS05745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMCC26103_RS05750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26103_RS05755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMCC26103_RS05760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMCC26103_RS05775	COG0275	rRNA processing
IMCC26103_RS05780	COG2001	Belongs to the MraZ family
IMCC26103_RS05790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMCC26103_RS05795	COG0587	DNA-directed DNA polymerase activity
IMCC26103_RS05810	COG0730	response to heat
IMCC26103_RS05825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMCC26103_RS05835	COG0596	Alpha beta hydrolase
IMCC26103_RS05850	COG0463	Glycosyl transferase, family 2
IMCC26103_RS05860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMCC26103_RS05870	COG0142	geranyltranstransferase activity
IMCC26103_RS05890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMCC26103_RS05890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMCC26103_RS05895	COG0515	serine threonine protein kinase
IMCC26103_RS05895	COG2815	serine threonine protein kinase
IMCC26103_RS05900	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IMCC26103_RS05920	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IMCC26103_RS05925	COG0205	6-phosphofructokinase activity
IMCC26103_RS05930	COG1070	Carbohydrate kinase
IMCC26103_RS05935	COG0697	spore germination
IMCC26103_RS05940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMCC26103_RS05950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMCC26103_RS05955	COG0681	Belongs to the peptidase S26 family
IMCC26103_RS05960	COG0335	large ribosomal subunit rRNA binding
IMCC26103_RS05975	COG2313	pseudouridylate synthase activity
IMCC26103_RS05980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26103_RS05985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMCC26103_RS05990	COG0488	(ABC) transporter
IMCC26103_RS06005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMCC26103_RS06015	COG1940	carbohydrate kinase activity
IMCC26103_RS06055	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS06060	COG0673	inositol 2-dehydrogenase activity
IMCC26103_RS06075	COG3254	rhamnose metabolic process
IMCC26103_RS06085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IMCC26103_RS06110	COG0395	ABC-type sugar transport system, permease component
IMCC26103_RS06115	COG1175	transmembrane transport
IMCC26103_RS06130	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26103_RS06145	COG4948	Mandelate Racemase Muconate Lactonizing
IMCC26103_RS06150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMCC26103_RS06165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMCC26103_RS06170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMCC26103_RS06180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMCC26103_RS06200	COG1832	CoA-binding protein
IMCC26103_RS06210	COG0662	Cupin 2, conserved barrel domain protein
IMCC26103_RS06240	COG0395	ABC-type sugar transport system, permease component
IMCC26103_RS06255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IMCC26103_RS06265	COG3254	rhamnose metabolic process
IMCC26103_RS06275	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS06275	COG3347	Dehydrogenase
IMCC26103_RS06280	COG1070	Carbohydrate kinase
IMCC26103_RS06300	COG1064	alcohol dehydrogenase
IMCC26103_RS06315	COG4608	Belongs to the ABC transporter superfamily
IMCC26103_RS06330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC26103_RS06345	COG2267	carboxylic ester hydrolase activity
IMCC26103_RS06350	COG3046	protein related to deoxyribodipyrimidine photolyase
IMCC26103_RS06370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IMCC26103_RS06380	COG3962	Belongs to the TPP enzyme family
IMCC26103_RS06390	COG1744	ABC transporter substrate-binding protein PnrA-like
IMCC26103_RS06395	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMCC26103_RS06400	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMCC26103_RS06405	COG3845	ABC transporter
IMCC26103_RS06410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IMCC26103_RS06415	COG0402	S-adenosylhomocysteine deaminase activity
IMCC26103_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
IMCC26103_RS06435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMCC26103_RS06435	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IMCC26103_RS06440	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMCC26103_RS06465	COG0537	adenosine 5'-monophosphoramidase activity
IMCC26103_RS06470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMCC26103_RS06475	COG0484	heat shock protein binding
IMCC26103_RS06480	COG1420	regulation of RNA biosynthetic process
IMCC26103_RS06495	COG0481	GTPase activity
IMCC26103_RS06500	COG0268	Binds directly to 16S ribosomal RNA
IMCC26103_RS06515	COG1596	polysaccharide export
IMCC26103_RS06515	COG1555	photosystem II stabilization
IMCC26103_RS06520	COG0495	leucyl-tRNA aminoacylation
IMCC26103_RS06540	COG0799	negative regulation of ribosome biogenesis
IMCC26103_RS06545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMCC26103_RS06550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMCC26103_RS06555	COG0482	sulfurtransferase activity
IMCC26103_RS06565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMCC26103_RS06575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMCC26103_RS06575	COG0438	transferase activity, transferring glycosyl groups
IMCC26103_RS06580	COG0438	transferase activity, transferring glycosyl groups
IMCC26103_RS06595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMCC26103_RS06600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMCC26103_RS06630	COG1278	Cold shock
IMCC26103_RS06655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMCC26103_RS06670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMCC26103_RS06680	COG3718	enzyme involved in inositol metabolism
IMCC26103_RS06690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMCC26103_RS06715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMCC26103_RS06720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMCC26103_RS06730	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMCC26103_RS06740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMCC26103_RS06760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IMCC26103_RS06765	COG2949	membrane
IMCC26103_RS06775	COG0423	glycine-tRNA ligase activity
IMCC26103_RS06790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMCC26103_RS06795	COG1381	Involved in DNA repair and RecF pathway recombination
IMCC26103_RS06800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMCC26103_RS06820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMCC26103_RS06820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMCC26103_RS06825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IMCC26103_RS06845	COG3590	peptidase
IMCC26103_RS06850	COG1063	alcohol dehydrogenase
IMCC26103_RS06855	COG4608	Belongs to the ABC transporter superfamily
IMCC26103_RS06860	COG0444	Belongs to the ABC transporter superfamily
IMCC26103_RS06875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMCC26103_RS06885	COG0477	Major facilitator Superfamily
IMCC26103_RS06890	COG0343	queuine tRNA-ribosyltransferase activity
IMCC26103_RS06910	COG1982	Orn Lys Arg decarboxylase major
IMCC26103_RS06925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMCC26103_RS06930	COG0581	inorganic phosphate transmembrane transporter activity
IMCC26103_RS06945	COG5002	protein histidine kinase activity
IMCC26103_RS06955	COG0277	FAD linked oxidase domain protein
IMCC26103_RS06960	COG1968	undecaprenyl-diphosphatase activity
IMCC26103_RS06975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMCC26103_RS07040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IMCC26103_RS07110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IMCC26103_RS07115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMCC26103_RS07120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMCC26103_RS07125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMCC26103_RS07130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC26103_RS07135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMCC26103_RS07140	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMCC26103_RS07145	COG0356	it plays a direct role in the translocation of protons across the membrane
IMCC26103_RS07160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMCC26103_RS07165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMCC26103_RS07175	COG2890	protein-(glutamine-N5) methyltransferase activity
IMCC26103_RS07180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMCC26103_RS07185	COG0254	rRNA binding
IMCC26103_RS07200	COG0083	homoserine kinase activity
IMCC26103_RS07205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMCC26103_RS07210	COG0460	homoserine dehydrogenase
IMCC26103_RS07220	COG0018	arginyl-trna synthetase
IMCC26103_RS07265	COG2755	lipolytic protein G-D-S-L family
IMCC26103_RS07265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMCC26103_RS07275	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMCC26103_RS07280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMCC26103_RS07285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMCC26103_RS07310	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IMCC26103_RS07325	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMCC26103_RS07345	COG1054	Belongs to the UPF0176 family
IMCC26103_RS07350	COG1741	Belongs to the pirin family