locus-tag	class	description
Asera_RS00020	COG0488	(ABC) transporter
Asera_RS00030	COG2814	Major facilitator Superfamily
Asera_RS00045	COG0604	alcohol dehydrogenase
Asera_RS00045	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS00045	COG3321	synthase
Asera_RS00080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Asera_RS00105	COG2172	sigma factor antagonist activity
Asera_RS00110	COG1191	sigma factor activity
Asera_RS00140	COG1672	PFAM Archaeal ATPase
Asera_RS00140	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asera_RS00155	COG4770	biotin carboxylase activity
Asera_RS00185	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asera_RS00185	COG1473	amidohydrolase
Asera_RS00190	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_RS00190	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_RS00195	COG2815	serine threonine protein kinase
Asera_RS00195	COG0515	serine threonine protein kinase
Asera_RS00200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asera_RS00205	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Asera_RS00215	COG2030	dehydratase
Asera_RS00220	COG2197	response regulator
Asera_RS00225	COG2409	Drug exporters of the RND superfamily
Asera_RS00250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asera_RS00260	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_RS00260	COG0204	Acyl-transferase
Asera_RS00265	COG0604	alcohol dehydrogenase
Asera_RS00265	COG3321	synthase
Asera_RS00275	COG0475	glutathione-regulated potassium exporter activity
Asera_RS00305	COG2132	Multicopper oxidase
Asera_RS00315	COG3226	Transcriptional regulator
Asera_RS00325	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Asera_RS00330	COG1012	belongs to the aldehyde dehydrogenase family
Asera_RS00335	COG1012	belongs to the aldehyde dehydrogenase family
Asera_RS00360	COG2018	Roadblock/LC7 domain
Asera_RS00370	COG0747	negative chemotaxis
Asera_RS00380	COG4608	Belongs to the ABC transporter superfamily
Asera_RS00385	COG0444	Belongs to the ABC transporter superfamily
Asera_RS00395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS00400	COG2154	pterin-4-alpha-carbinolamine dehydratase
Asera_RS00410	COG1053	succinate dehydrogenase
Asera_RS00425	COG4762	Protein conserved in bacteria
Asera_RS00430	COG0494	nUDIX hydrolase
Asera_RS00445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_RS00455	COG0640	Transcriptional regulator
Asera_RS00485	COG2076	Multidrug Resistance protein
Asera_RS00510	COG0012	GTP binding
Asera_RS00520	COG4585	Histidine kinase
Asera_RS00525	COG2197	response regulator
Asera_RS00530	COG2409	Drug exporters of the RND superfamily
Asera_RS00545	COG2169	Transcriptional regulator
Asera_RS00545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Asera_RS00560	COG1132	(ABC) transporter
Asera_RS00575	COG0525	valine-tRNA ligase activity
Asera_RS00590	COG1322	Protein conserved in bacteria
Asera_RS00605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Asera_RS00610	COG1570	exodeoxyribonuclease VII activity
Asera_RS00615	COG1722	exodeoxyribonuclease VII activity
Asera_RS00640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Asera_RS00650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Asera_RS00670	COG1331	Highly conserved protein containing a thioredoxin domain
Asera_RS00695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_RS00725	COG1051	belongs to the nudix hydrolase family
Asera_RS00750	COG0537	adenosine 5'-monophosphoramidase activity
Asera_RS00755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asera_RS00780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Asera_RS00790	COG3467	pyridoxamine 5'-phosphate
Asera_RS00795	COG2755	lipolytic protein G-D-S-L family
Asera_RS00805	COG0183	Belongs to the thiolase family
Asera_RS00835	COG0076	glutamate decarboxylase activity
Asera_RS00860	COG0328	RNA-DNA hybrid ribonuclease activity
Asera_RS00875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asera_RS00885	COG1252	NADH dehydrogenase
Asera_RS00900	COG0714	Associated with various cellular activities
Asera_RS00935	COG0148	phosphopyruvate hydratase activity
Asera_RS01000	COG2409	Drug exporters of the RND superfamily
Asera_RS01030	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_RS01075	COG0326	Molecular chaperone. Has ATPase activity
Asera_RS01085	COG1846	Transcriptional regulator
Asera_RS01090	COG0655	NAD(P)H dehydrogenase (quinone) activity
Asera_RS01100	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Asera_RS01105	COG0529	Catalyzes the synthesis of activated sulfate
Asera_RS01110	COG0730	response to heat
Asera_RS01150	COG2755	lipolytic protein G-D-S-L family
Asera_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS01170	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Asera_RS01200	COG0604	alcohol dehydrogenase
Asera_RS01200	COG3321	synthase
Asera_RS01220	COG1218	3'(2'),5'-bisphosphate nucleotidase
Asera_RS01225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asera_RS01230	COG0193	aminoacyl-tRNA hydrolase activity
Asera_RS01235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Asera_RS01240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Asera_RS01245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Asera_RS01275	COG0488	(ABC) transporter
Asera_RS01280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Asera_RS01300	COG0084	hydrolase, TatD family'
Asera_RS01305	COG1253	flavin adenine dinucleotide binding
Asera_RS01310	COG1253	flavin adenine dinucleotide binding
Asera_RS01315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asera_RS01360	COG0443	Heat shock 70 kDa protein
Asera_RS01385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_RS01450	COG1674	ftsk spoiiie
Asera_RS01520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Asera_RS01565	COG3842	ATPase activity
Asera_RS01605	COG1937	Protein conserved in bacteria
Asera_RS01610	COG0791	NLP P60 protein
Asera_RS01610	COG3883	PFAM NLP P60 protein
Asera_RS01625	COG2318	DinB family
Asera_RS01645	COG0142	geranyltranstransferase activity
Asera_RS01695	COG4152	abc transporter atp-binding protein
Asera_RS01700	COG1668	transmembrane transport
Asera_RS01705	COG0667	Aldo Keto reductase
Asera_RS01720	COG2814	Major facilitator Superfamily
Asera_RS01725	COG0583	DNA-binding transcription factor activity
Asera_RS01745	COG2271	Major facilitator Superfamily
Asera_RS01755	COG0242	peptide deformylase activity
Asera_RS01790	COG1760	l-serine dehydratase
Asera_RS01795	COG2814	Major facilitator Superfamily
Asera_RS01825	COG2017	converts alpha-aldose to the beta-anomer
Asera_RS01830	COG1733	regulation of RNA biosynthetic process
Asera_RS01845	COG0259	pyridoxamine-phosphate oxidase activity
Asera_RS01855	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Asera_RS01870	COG1131	(ABC) transporter
Asera_RS01880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Asera_RS01905	COG2252	PERMEase
Asera_RS01910	COG2205	protein histidine kinase activity
Asera_RS01915	COG0745	RESPONSE REGULATOR receiver
Asera_RS01955	COG2814	Major facilitator Superfamily
Asera_RS01970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Asera_RS01975	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Asera_RS01985	COG1278	Cold shock
Asera_RS01995	COG0584	glycerophosphoryl diester phosphodiesterase
Asera_RS02025	COG4991	sh3 domain protein
Asera_RS02055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Asera_RS02060	COG1595	DNA-templated transcription, initiation
Asera_RS02065	COG1252	NADH dehydrogenase
Asera_RS02070	COG1522	sequence-specific DNA binding
Asera_RS02105	COG0456	acetyltransferase
Asera_RS02110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_RS02120	COG1737	Transcriptional regulator
Asera_RS02125	COG3876	Protein conserved in bacteria
Asera_RS02130	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_RS02135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Asera_RS02150	COG0459	protein refolding
Asera_RS02175	COG1278	Cold shock
Asera_RS02185	COG0456	acetyltransferase
Asera_RS02200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Asera_RS02210	COG0640	Transcriptional regulator
Asera_RS02225	COG1131	(ABC) transporter
Asera_RS02230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asera_RS02235	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Asera_RS02280	COG0681	Belongs to the peptidase S26 family
Asera_RS02285	COG4608	Belongs to the ABC transporter superfamily
Asera_RS02290	COG0444	Belongs to the ABC transporter superfamily
Asera_RS02305	COG4166	transmembrane transport
Asera_RS02310	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_RS02320	COG1349	DNA-binding transcription factor activity
Asera_RS02330	COG1940	carbohydrate kinase activity
Asera_RS02355	COG1595	DNA-templated transcription, initiation
Asera_RS02375	COG1733	regulation of RNA biosynthetic process
Asera_RS02405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Asera_RS02410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Asera_RS02425	COG1309	transcriptional regulator
Asera_RS02470	COG0456	acetyltransferase
Asera_RS02490	COG0110	maltose O-acetyltransferase activity
Asera_RS02525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Asera_RS02525	COG1754	DNA topoisomerase type I activity
Asera_RS02550	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Asera_RS02560	COG1366	Belongs to the anti-sigma-factor antagonist family
Asera_RS02565	COG1111	helicase
Asera_RS02565	COG1205	dead DEAH box helicase
Asera_RS02570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_RS02610	COG0488	(ABC) transporter
Asera_RS02620	COG0789	Transcriptional regulator
Asera_RS02690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_RS02715	COG1733	regulation of RNA biosynthetic process
Asera_RS02735	COG1051	belongs to the nudix hydrolase family
Asera_RS02760	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_RS02775	COG0560	Phosphoserine phosphatase
Asera_RS02815	COG0506	proline dehydrogenase activity
Asera_RS02820	COG0649	NAD binding
Asera_RS02835	COG1174	glycine betaine transport
Asera_RS02840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asera_RS02845	COG1125	glycine betaine transport
Asera_RS02845	COG0517	IMP dehydrogenase activity
Asera_RS02855	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_RS02865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Asera_RS02870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Asera_RS02945	COG1404	Belongs to the peptidase S8 family
Asera_RS02965	COG0302	gtp cyclohydrolase
Asera_RS02970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asera_RS02975	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Asera_RS03005	COG1774	PSP1 C-terminal conserved region
Asera_RS03035	COG1175	transmembrane transport
Asera_RS03040	COG0395	ABC-type sugar transport system, permease component
Asera_RS03050	COG0584	glycerophosphoryl diester phosphodiesterase
Asera_RS03070	COG1846	Transcriptional regulator
Asera_RS03070	COG0456	acetyltransferase
Asera_RS03085	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_RS03095	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Asera_RS03100	COG2027	D-alanyl-D-alanine carboxypeptidase
Asera_RS03110	COG0037	tRNA processing
Asera_RS03130	COG3263	regulation of cellular component size
Asera_RS03150	COG1309	transcriptional regulator
Asera_RS03155	COG2814	Major facilitator Superfamily
Asera_RS03160	COG3104	oligopeptide transport
Asera_RS03165	COG1653	transport
Asera_RS03170	COG0395	ABC-type sugar transport system, permease component
Asera_RS03175	COG1175	transmembrane transport
Asera_RS03195	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Asera_RS03220	COG3842	ATPase activity
Asera_RS03235	COG0215	cysteine-tRNA ligase activity
Asera_RS03245	COG0114	fumarate hydratase activity
Asera_RS03260	COG0163	prenyltransferase activity
Asera_RS03275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Asera_RS03280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Asera_RS03285	COG3548	integral membrane protein
Asera_RS03295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Asera_RS03310	COG0789	Transcriptional regulator
Asera_RS03325	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Asera_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS03355	COG3246	L-lysine catabolic process to acetate
Asera_RS03375	COG4044	May play a role in the intracellular transport of hydrophobic ligands
Asera_RS03385	COG0025	NhaP-type Na H and K H
Asera_RS03430	COG0745	RESPONSE REGULATOR receiver
Asera_RS03435	COG0456	acetyltransferase
Asera_RS03445	COG1131	(ABC) transporter
Asera_RS03455	COG4585	Histidine kinase
Asera_RS03460	COG2197	response regulator
Asera_RS03465	COG0842	Transport permease protein
Asera_RS03465	COG1131	(ABC) transporter
Asera_RS03465	COG1716	ATPase activity
Asera_RS03480	COG1846	Transcriptional regulator
Asera_RS03490	COG0604	alcohol dehydrogenase
Asera_RS03490	COG3321	synthase
Asera_RS03495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_RS03505	COG0667	Aldo Keto reductase
Asera_RS03525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Asera_RS03570	COG1653	transport
Asera_RS03575	COG1653	transport
Asera_RS03585	COG1175	transmembrane transport
Asera_RS03590	COG0673	inositol 2-dehydrogenase activity
Asera_RS03595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Asera_RS03600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asera_RS03605	COG0494	nUDIX hydrolase
Asera_RS03640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Asera_RS03645	COG0596	Alpha beta hydrolase
Asera_RS03655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asera_RS03680	COG0577	efflux transmembrane transporter activity
Asera_RS03685	COG1595	DNA-templated transcription, initiation
Asera_RS03715	COG1366	Belongs to the anti-sigma-factor antagonist family
Asera_RS03725	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Asera_RS03735	COG1793	dna ligase
Asera_RS03735	COG3285	dna ligase
Asera_RS03790	COG1309	transcriptional regulator
Asera_RS03810	COG0367	asparagine synthase
Asera_RS03825	COG1072	(Pantothenic acid kinase))
Asera_RS03835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asera_RS03840	COG3387	PFAM Glycoside hydrolase 15-related
Asera_RS03845	COG0439	Biotin carboxylase
Asera_RS03855	COG0640	Transcriptional regulator
Asera_RS03905	COG4974	Belongs to the 'phage' integrase family
Asera_RS03920	COG1191	sigma factor activity
Asera_RS03985	COG0702	epimerase
Asera_RS04015	COG4585	Histidine kinase
Asera_RS04035	COG1064	alcohol dehydrogenase
Asera_RS04050	COG1595	DNA-templated transcription, initiation
Asera_RS04055	COG0583	DNA-binding transcription factor activity
Asera_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS04120	COG0667	Aldo Keto reductase
Asera_RS04135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asera_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS04155	COG2197	response regulator
Asera_RS04170	COG0235	Class ii aldolase
Asera_RS04175	COG0477	Major facilitator Superfamily
Asera_RS04180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_RS04185	COG0765	amino acid transport
Asera_RS04190	COG0765	amino acid transport
Asera_RS04225	COG0673	inositol 2-dehydrogenase activity
Asera_RS04255	COG0789	Transcriptional regulator
Asera_RS04260	COG2130	NADP-dependent
Asera_RS04265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Asera_RS04270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Asera_RS04305	COG0778	Nitroreductase
Asera_RS04310	COG1051	belongs to the nudix hydrolase family
Asera_RS04320	COG0596	Alpha beta hydrolase
Asera_RS04340	COG1597	lipid kinase activity
Asera_RS04350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_RS04355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_RS04385	COG1309	transcriptional regulator
Asera_RS04390	COG0686	Belongs to the AlaDH PNT family
Asera_RS04405	COG2186	Transcriptional regulator
Asera_RS04410	COG2050	protein possibly involved in aromatic compounds catabolism
Asera_RS04420	COG2226	methyltransferase
Asera_RS04425	COG1024	Enoyl-CoA hydratase
Asera_RS04430	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_RS04455	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
Asera_RS04455	COG0778	Nitroreductase
Asera_RS04470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Asera_RS04495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Asera_RS04530	COG1131	(ABC) transporter
Asera_RS04545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Asera_RS04550	COG0047	phosphoribosylformylglycinamidine synthase activity
Asera_RS04560	COG0640	Transcriptional regulator
Asera_RS04570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Asera_RS04575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Asera_RS04590	COG0151	Belongs to the GarS family
Asera_RS04595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Asera_RS04610	COG1733	regulation of RNA biosynthetic process
Asera_RS04630	COG0191	fructose-bisphosphate aldolase activity
Asera_RS04640	COG1355	regulation of microtubule-based process
Asera_RS04670	COG0586	Pfam SNARE associated Golgi protein
Asera_RS04680	COG0640	Transcriptional regulator
Asera_RS04685	COG1619	proteins homologs of microcin C7 resistance protein MccF
Asera_RS04690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Asera_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS04710	COG0542	response to heat
Asera_RS04735	COG0475	glutathione-regulated potassium exporter activity
Asera_RS04750	COG0789	Transcriptional regulator
Asera_RS04755	COG0484	heat shock protein binding
Asera_RS04760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Asera_RS04765	COG0443	Heat shock 70 kDa protein
Asera_RS04775	COG0247	lactate metabolic process
Asera_RS04775	COG2181	nitrate reductase activity
Asera_RS04815	COG0717	Belongs to the dCTP deaminase family
Asera_RS04900	COG2186	Transcriptional regulator
Asera_RS04945	COG3328	transposase activity
Asera_RS04950	COG3629	intracellular signal transduction
Asera_RS04950	COG3903	Transcriptional regulator
Asera_RS04990	COG0656	L-ascorbic acid biosynthetic process
Asera_RS05000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asera_RS05060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asera_RS05065	COG1834	amidinotransferase
Asera_RS05070	COG1522	sequence-specific DNA binding
Asera_RS05085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Asera_RS05130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asera_RS05130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Asera_RS05170	COG0210	DNA helicase
Asera_RS05200	COG0745	RESPONSE REGULATOR receiver
Asera_RS05205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Asera_RS05250	COG0022	dehydrogenase e1 component
Asera_RS05255	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_RS05270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Asera_RS05275	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Asera_RS05280	COG1984	allophanate hydrolase subunit 2
Asera_RS05285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Asera_RS05305	COG1960	acyl-CoA dehydrogenase activity
Asera_RS05315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Asera_RS05350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Asera_RS05380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Asera_RS05430	COG0315	cyclic pyranopterin monophosphate synthase activity
Asera_RS05435	COG1716	ATPase activity
Asera_RS05435	COG5001	Diguanylate cyclase
Asera_RS05455	COG2186	Transcriptional regulator
Asera_RS05465	COG0667	Aldo Keto reductase
Asera_RS05475	COG0305	Participates in initiation and elongation during chromosome replication
Asera_RS05480	COG1796	DNA polymerase
Asera_RS05480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Asera_RS05500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asera_RS05515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_RS05525	COG0359	binds to the 23S rRNA
Asera_RS05530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Asera_RS05535	COG0629	single-stranded DNA binding
Asera_RS05540	COG0360	Binds together with S18 to 16S ribosomal RNA
Asera_RS05570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_RS05595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_RS05600	COG2027	D-alanyl-D-alanine carboxypeptidase
Asera_RS05610	COG2268	Band 7 protein
Asera_RS05615	COG2132	Multicopper oxidase
Asera_RS05655	COG0617	tRNA 3'-terminal CCA addition
Asera_RS05680	COG0433	COG0433 Predicted ATPase
Asera_RS05690	COG1595	DNA-templated transcription, initiation
Asera_RS05705	COG3118	belongs to the thioredoxin family
Asera_RS05710	COG0860	N-Acetylmuramoyl-L-alanine amidase
Asera_RS05710	COG3409	Peptidoglycan-binding domain 1 protein
Asera_RS05720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS05725	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asera_RS05730	COG2382	esterase
Asera_RS05730	COG3507	Belongs to the glycosyl hydrolase 43 family
Asera_RS05730	COG3693	PFAM glycoside hydrolase, family 10
Asera_RS05740	COG1247	-acetyltransferase
Asera_RS05750	COG1192	Involved in chromosome partitioning
Asera_RS05755	COG0357	Ribosomal RNA small subunit methyltransferase G
Asera_RS05770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Asera_RS05775	COG0594	ribonuclease P activity
Asera_RS05780	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Asera_RS05785	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Asera_RS05790	COG0592	DNA-directed DNA polymerase activity
Asera_RS05795	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Asera_RS05800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Asera_RS05805	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Asera_RS05820	COG1595	DNA-templated transcription, initiation
Asera_RS05830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Asera_RS05875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Asera_RS05890	COG0402	S-adenosylhomocysteine deaminase activity
Asera_RS05940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_RS06000	COG0439	Biotin carboxylase
Asera_RS06005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asera_RS06015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_RS06030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Asera_RS06035	COG1960	acyl-CoA dehydrogenase activity
Asera_RS06050	COG1881	PFAM PEBP family protein
Asera_RS06070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS06075	COG0598	Magnesium transport protein CorA
Asera_RS06100	COG1309	transcriptional regulator
Asera_RS06110	COG0183	Belongs to the thiolase family
Asera_RS06145	COG0515	serine threonine protein kinase
Asera_RS06145	COG2815	serine threonine protein kinase
Asera_RS06150	COG0515	serine threonine protein kinase
Asera_RS06155	COG0768	penicillin binding
Asera_RS06170	COG1716	ATPase activity
Asera_RS06175	COG1716	ATPase activity
Asera_RS06175	COG1716	ATPase activity
Asera_RS06185	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS06190	COG1309	transcriptional regulator
Asera_RS06195	COG4221	oxidoreductase activity
Asera_RS06215	COG1846	Transcriptional regulator
Asera_RS06230	COG1132	(ABC) transporter
Asera_RS06235	COG3559	Exporter of polyketide antibiotics
Asera_RS06240	COG1131	(ABC) transporter
Asera_RS06250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_RS06260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS06265	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Asera_RS06325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Asera_RS06355	COG2026	Addiction module toxin, RelE StbE family
Asera_RS06360	COG0438	transferase activity, transferring glycosyl groups
Asera_RS06365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_RS06375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Asera_RS06385	COG1316	TRANSCRIPTIONal
Asera_RS06390	COG1316	TRANSCRIPTIONal
Asera_RS06400	COG5002	protein histidine kinase activity
Asera_RS06415	COG0604	alcohol dehydrogenase
Asera_RS06430	COG2837	iron assimilation
Asera_RS06440	COG0672	)-iron permease
Asera_RS06470	COG1234	tRNA 3'-trailer cleavage
Asera_RS06475	COG4991	sh3 domain protein
Asera_RS06510	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Asera_RS06525	COG2226	methyltransferase
Asera_RS06555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Asera_RS06570	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Asera_RS06575	COG0583	DNA-binding transcription factor activity
Asera_RS06595	COG0584	glycerophosphoryl diester phosphodiesterase
Asera_RS06605	COG1021	2,3-dihydroxybenzoate-AMP ligase
Asera_RS06610	COG0189	ligase activity
Asera_RS06645	COG0205	6-phosphofructokinase activity
Asera_RS06655	COG1733	regulation of RNA biosynthetic process
Asera_RS06665	COG1846	Transcriptional regulator
Asera_RS06670	COG0546	phosphoglycolate phosphatase activity
Asera_RS06675	COG4585	Histidine kinase
Asera_RS06680	COG2197	response regulator
Asera_RS06705	COG2197	response regulator
Asera_RS06710	COG4585	Histidine kinase
Asera_RS06725	COG0789	Transcriptional regulator
Asera_RS06730	COG3959	Transketolase, thiamine diphosphate binding domain
Asera_RS06735	COG3958	Transketolase
Asera_RS06785	COG0561	phosphatase activity
Asera_RS06800	COG0561	phosphatase activity
Asera_RS06805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Asera_RS06810	COG1764	response to oxidative stress
Asera_RS06840	COG0745	RESPONSE REGULATOR receiver
Asera_RS06850	COG0500	methyltransferase
Asera_RS06855	COG0588	phosphoglycerate mutase activity
Asera_RS06865	COG1414	Transcriptional regulator
Asera_RS06885	COG4106	trans-aconitate 2-methyltransferase activity
Asera_RS06900	COG1691	(AIR) carboxylase
Asera_RS06905	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Asera_RS06910	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Asera_RS06955	COG2205	protein histidine kinase activity
Asera_RS06960	COG0745	RESPONSE REGULATOR receiver
Asera_RS06975	COG0577	efflux transmembrane transporter activity
Asera_RS06975	COG1136	(ABC) transporter
Asera_RS06980	COG0577	efflux transmembrane transporter activity
Asera_RS06985	COG0702	epimerase
Asera_RS07005	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Asera_RS07025	COG0640	Transcriptional regulator
Asera_RS07030	COG0583	DNA-binding transcription factor activity
Asera_RS07065	COG0640	Transcriptional regulator
Asera_RS07075	COG0640	Transcriptional regulator
Asera_RS07080	COG2072	flavoprotein involved in K transport
Asera_RS07090	COG2072	flavoprotein involved in K transport
Asera_RS07100	COG0798	PFAM Bile acid sodium symporter
Asera_RS07105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Asera_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS07130	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS07155	COG1280	lysine exporter protein (LysE YggA)
Asera_RS07165	COG0110	maltose O-acetyltransferase activity
Asera_RS07170	COG1309	transcriptional regulator
Asera_RS07210	COG0384	phenazine biosynthesis protein PhzF
Asera_RS07235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Asera_RS07255	COG0640	Transcriptional regulator
Asera_RS07285	COG1376	ErfK ybiS ycfS ynhG family protein
Asera_RS07325	COG4941	Belongs to the sigma-70 factor family
Asera_RS07335	COG2197	response regulator
Asera_RS07350	COG1136	(ABC) transporter
Asera_RS07355	COG0110	maltose O-acetyltransferase activity
Asera_RS07400	COG2197	response regulator
Asera_RS07510	COG1846	Transcriptional regulator
Asera_RS07510	COG1940	carbohydrate kinase activity
Asera_RS07530	COG2318	DinB family
Asera_RS07535	COG1473	amidohydrolase
Asera_RS07540	COG0477	Major facilitator Superfamily
Asera_RS07550	COG2814	Major facilitator Superfamily
Asera_RS07560	COG1120	ATPase activity
Asera_RS07600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Asera_RS07605	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Asera_RS07610	COG1414	Transcriptional regulator
Asera_RS07620	COG0800	Aldolase
Asera_RS07635	COG1609	Transcriptional regulator
Asera_RS07650	COG0747	negative chemotaxis
Asera_RS07655	COG4166	transmembrane transport
Asera_RS07665	COG0406	alpha-ribazole phosphatase activity
Asera_RS07675	COG0601	transmembrane transport
Asera_RS07680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS07690	COG4608	Belongs to the ABC transporter superfamily
Asera_RS07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_RS07725	COG0765	amino acid transport
Asera_RS07730	COG0765	amino acid transport
Asera_RS07735	COG1126	abc transporter atp-binding protein
Asera_RS07750	COG2186	Transcriptional regulator
Asera_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS07770	COG0395	ABC-type sugar transport system, permease component
Asera_RS07785	COG0477	Major facilitator Superfamily
Asera_RS07800	COG1902	pentaerythritol trinitrate reductase activity
Asera_RS07805	COG2936	dipeptidyl-peptidase activity
Asera_RS07820	COG1796	DNA polymerase
Asera_RS07820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Asera_RS07825	COG0235	Class ii aldolase
Asera_RS07825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Asera_RS07830	COG0287	Prephenate dehydrogenase
Asera_RS07860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Asera_RS07865	COG0813	purine-nucleoside phosphorylase activity
Asera_RS07875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS07915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Asera_RS08045	COG0789	Transcriptional regulator
Asera_RS08065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_RS08075	COG0789	Transcriptional regulator
Asera_RS08100	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Asera_RS08105	COG0693	protein deglycase activity
Asera_RS08125	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Asera_RS08130	COG0583	DNA-binding transcription factor activity
Asera_RS08170	COG0477	Major facilitator Superfamily
Asera_RS08175	COG0443	Heat shock 70 kDa protein
Asera_RS08180	COG0776	regulation of translation
Asera_RS08195	COG2814	Major facilitator Superfamily
Asera_RS08220	COG1131	(ABC) transporter
Asera_RS08225	COG4585	Histidine kinase
Asera_RS08230	COG2197	response regulator
Asera_RS08235	COG1309	transcriptional regulator
Asera_RS08240	COG0477	Major facilitator Superfamily
Asera_RS08245	COG0583	DNA-binding transcription factor activity
Asera_RS08250	COG0300	oxidoreductase activity
Asera_RS08275	COG1309	transcriptional regulator
Asera_RS08280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asera_RS08310	COG1309	transcriptional regulator
Asera_RS08315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Asera_RS08330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Asera_RS08395	COG0003	Pfam Anion-transporting ATPase
Asera_RS08405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_RS08415	COG1408	metallophosphoesterase
Asera_RS08515	COG0583	DNA-binding transcription factor activity
Asera_RS08540	COG0183	Belongs to the thiolase family
Asera_RS08560	COG0477	Major facilitator Superfamily
Asera_RS08575	COG1595	DNA-templated transcription, initiation
Asera_RS08595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_RS08615	COG1674	ftsk spoiiie
Asera_RS08650	COG3706	GGDEF domain
Asera_RS08655	COG1716	ATPase activity
Asera_RS08665	COG0745	RESPONSE REGULATOR receiver
Asera_RS08670	COG2205	protein histidine kinase activity
Asera_RS08675	COG2197	response regulator
Asera_RS08680	COG2203	Gaf domain
Asera_RS08680	COG4585	Histidine kinase
Asera_RS08685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Asera_RS08695	COG3145	DNA-N1-methyladenine dioxygenase activity
Asera_RS08730	COG2378	regulation of single-species biofilm formation
Asera_RS08755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Asera_RS08760	COG0477	Major facilitator Superfamily
Asera_RS08765	COG4585	Histidine kinase
Asera_RS08770	COG2188	Transcriptional regulator
Asera_RS08790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_RS08805	COG0247	lactate metabolic process
Asera_RS08810	COG0277	FAD linked oxidase domain protein
Asera_RS08815	COG0277	FAD linked oxidase domain protein
Asera_RS08820	COG0702	epimerase
Asera_RS08840	COG0784	Response regulator, receiver
Asera_RS08840	COG2198	Histidine kinase
Asera_RS08840	COG2205	protein histidine kinase activity
Asera_RS08855	COG0671	phosphoesterase, PA-phosphatase related
Asera_RS08870	COG1404	Belongs to the peptidase S8 family
Asera_RS08910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asera_RS08915	COG2197	response regulator
Asera_RS08925	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Asera_RS08930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Asera_RS08935	COG0181	hydroxymethylbilane synthase activity
Asera_RS08940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Asera_RS08940	COG1648	precorrin-2 dehydrogenase activity
Asera_RS08945	COG0113	porphobilinogen synthase activity
Asera_RS08960	COG3328	transposase activity
Asera_RS08980	COG0765	amino acid transport
Asera_RS08985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_RS09000	COG3469	chitinase activity
Asera_RS09015	COG4941	Belongs to the sigma-70 factor family
Asera_RS09020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_RS09045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Asera_RS09050	COG0406	alpha-ribazole phosphatase activity
Asera_RS09055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asera_RS09060	COG0785	Cytochrome C biogenesis protein
Asera_RS09065	COG1333	cytochrome c biogenesis protein
Asera_RS09070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Asera_RS09095	COG3896	Chloramphenicol phosphotransferase-like protein
Asera_RS09115	COG0438	transferase activity, transferring glycosyl groups
Asera_RS09135	COG0588	phosphoglycerate mutase activity
Asera_RS09155	COG0745	RESPONSE REGULATOR receiver
Asera_RS09160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Asera_RS09175	COG1082	Xylose isomerase domain protein TIM barrel
Asera_RS09195	COG1175	transmembrane transport
Asera_RS09200	COG0395	ABC-type sugar transport system, permease component
Asera_RS09230	COG4585	Histidine kinase
Asera_RS09250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Asera_RS09255	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Asera_RS09260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Asera_RS09270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Asera_RS09280	COG0583	DNA-binding transcription factor activity
Asera_RS09285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Asera_RS09305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Asera_RS09325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Asera_RS09330	COG1194	a g-specific adenine glycosylase
Asera_RS09340	COG1595	DNA-templated transcription, initiation
Asera_RS09355	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Asera_RS09360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Asera_RS09375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asera_RS09380	COG1960	acyl-CoA dehydrogenase activity
Asera_RS09400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Asera_RS09405	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Asera_RS09435	COG4290	ribonuclease
Asera_RS09450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asera_RS09460	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Asera_RS09465	COG1522	sequence-specific DNA binding
Asera_RS09475	COG3654	unkown
Asera_RS09485	COG0542	response to heat
Asera_RS09520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Asera_RS09570	COG0405	Gamma-glutamyltransferase
Asera_RS09585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS09600	COG1802	Transcriptional regulator
Asera_RS09610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Asera_RS09615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Asera_RS09625	COG1252	NADH dehydrogenase
Asera_RS09630	COG3973	AAA domain
Asera_RS09640	COG1051	belongs to the nudix hydrolase family
Asera_RS09660	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Asera_RS09680	COG3396	Phenylacetate-CoA oxygenase
Asera_RS09685	COG3460	Phenylacetate-CoA oxygenase
Asera_RS09690	COG3396	Phenylacetate-CoA oxygenase
Asera_RS09695	COG2151	metal-sulfur cluster biosynthetic enzyme
Asera_RS09700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asera_RS09710	COG1022	Amp-dependent synthetase and ligase
Asera_RS09720	COG2050	protein possibly involved in aromatic compounds catabolism
Asera_RS09745	COG0644	oxidoreductase
Asera_RS09750	COG3396	Phenylacetate-CoA oxygenase
Asera_RS09755	COG2022	thiamine diphosphate biosynthetic process
Asera_RS09755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asera_RS09790	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Asera_RS09815	COG2226	methyltransferase
Asera_RS09830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_RS09835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_RS09840	COG0649	NAD binding
Asera_RS09850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Asera_RS09855	COG1034	ATP synthesis coupled electron transport
Asera_RS09860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Asera_RS09865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_RS09875	COG0713	ATP synthesis coupled electron transport
Asera_RS09890	COG1007	ATP synthesis coupled electron transport
Asera_RS09895	COG0142	geranyltranstransferase activity
Asera_RS09915	COG1404	Belongs to the peptidase S8 family
Asera_RS09950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Asera_RS09955	COG1950	PFAM Membrane protein of
Asera_RS09965	COG1309	transcriptional regulator
Asera_RS09975	COG1013	pyruvate-flavodoxin oxidoreductase activity
Asera_RS09980	COG0674	pyruvate-flavodoxin oxidoreductase activity
Asera_RS09980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Asera_RS10005	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_RS10010	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_RS10015	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_RS10020	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Asera_RS10035	COG0667	Aldo Keto reductase
Asera_RS10040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Asera_RS10050	COG0839	Belongs to the complex I subunit 6 family
Asera_RS10055	COG0713	ATP synthesis coupled electron transport
Asera_RS10060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Asera_RS10070	COG1007	ATP synthesis coupled electron transport
Asera_RS10075	COG0501	Belongs to the peptidase M48B family
Asera_RS10085	COG2267	carboxylic ester hydrolase activity
Asera_RS10090	COG2315	Protein conserved in bacteria
Asera_RS10095	COG1666	GTP binding
Asera_RS10335	COG3300	MHYT domain
Asera_RS10335	COG5001	Diguanylate cyclase
Asera_RS10350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Asera_RS10355	COG2030	dehydratase
Asera_RS10370	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Asera_RS10380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Asera_RS10385	COG0081	regulation of translation
Asera_RS10390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Asera_RS10395	COG0222	ribosome binding
Asera_RS10400	COG1127	ABC transporter
Asera_RS10405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Asera_RS10410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Asera_RS10435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Asera_RS10455	COG0085	RNA polymerase activity
Asera_RS10460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Asera_RS10475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Asera_RS10480	COG0049	tRNA binding
Asera_RS10485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Asera_RS10490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Asera_RS10495	COG0051	transcription antitermination factor activity, RNA binding
Asera_RS10500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Asera_RS10505	COG0088	Forms part of the polypeptide exit tunnel
Asera_RS10510	COG0089	rRNA binding
Asera_RS10515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Asera_RS10520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Asera_RS10525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Asera_RS10530	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Asera_RS10535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Asera_RS10540	COG0255	Belongs to the universal ribosomal protein uL29 family
Asera_RS10545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Asera_RS10550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Asera_RS10555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Asera_RS10560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Asera_RS10565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Asera_RS10570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Asera_RS10575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Asera_RS10580	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Asera_RS10585	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Asera_RS10590	COG1841	ribosomal large subunit assembly
Asera_RS10595	COG0200	Binds to the 23S rRNA
Asera_RS10605	COG0563	adenylate kinase activity
Asera_RS10620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Asera_RS10625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Asera_RS10630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Asera_RS10635	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Asera_RS10640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Asera_RS10645	COG0202	RNA polymerase activity
Asera_RS10650	COG0203	ribosomal protein L17
Asera_RS10655	COG0101	tRNA pseudouridine synthase activity
Asera_RS10690	COG0488	(ABC) transporter
Asera_RS10705	COG2814	Major facilitator Superfamily
Asera_RS10710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Asera_RS10715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Asera_RS10720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asera_RS10730	COG0583	DNA-binding transcription factor activity
Asera_RS10750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asera_RS10760	COG4977	sequence-specific DNA binding
Asera_RS10765	COG4115	mRNA cleavage
Asera_RS10770	COG2161	toxin-antitoxin pair type II binding
Asera_RS10775	COG0667	Aldo Keto reductase
Asera_RS10780	COG0443	Heat shock 70 kDa protein
Asera_RS10785	COG1505	serine-type exopeptidase activity
Asera_RS10790	COG0736	holo-[acyl-carrier-protein] synthase activity
Asera_RS10800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Asera_RS10810	COG0802	atpase or kinase
Asera_RS10815	COG2267	carboxylic ester hydrolase activity
Asera_RS10820	COG1214	PFAM Peptidase M22, glycoprotease
Asera_RS10820	COG0456	acetyltransferase
Asera_RS10830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Asera_RS10835	COG4585	Histidine kinase
Asera_RS10840	COG2197	response regulator
Asera_RS10865	COG1132	(ABC) transporter
Asera_RS10870	COG1132	(ABC) transporter
Asera_RS10880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_RS10885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Asera_RS10900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Asera_RS10905	COG0459	protein refolding
Asera_RS10920	COG2197	response regulator
Asera_RS10945	COG0516	GMP reductase activity
Asera_RS10955	COG0531	amino acid
Asera_RS11000	COG1175	transmembrane transport
Asera_RS11010	COG0395	ABC-type sugar transport system, permease component
Asera_RS11040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Asera_RS11040	COG0519	Catalyzes the synthesis of GMP from XMP
Asera_RS11050	COG1051	belongs to the nudix hydrolase family
Asera_RS11050	COG1056	cytidyltransferase-related domain
Asera_RS11055	COG1183	phosphatidylcholine synthase activity
Asera_RS11060	COG2197	response regulator
Asera_RS11085	COG0688	phosphatidylethanolamine metabolic process
Asera_RS11100	COG4585	Histidine kinase
Asera_RS11105	COG2197	response regulator
Asera_RS11120	COG1605	Chorismate mutase
Asera_RS11135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Asera_RS11150	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_RS11195	COG0138	bifunctional purine biosynthesis protein purh
Asera_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS11205	COG1733	regulation of RNA biosynthetic process
Asera_RS11230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asera_RS11265	COG1175	transmembrane transport
Asera_RS11270	COG0395	ABC-type sugar transport system, permease component
Asera_RS11285	COG1569	PIN domain
Asera_RS11290	COG3311	Transcriptional regulator
Asera_RS11295	COG0477	Major facilitator Superfamily
Asera_RS11315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Asera_RS11340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Asera_RS11345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Asera_RS11355	COG1349	DNA-binding transcription factor activity
Asera_RS11365	COG1175	transmembrane transport
Asera_RS11370	COG0395	ABC-type sugar transport system, permease component
Asera_RS11375	COG0180	Tryptophanyl-tRNA synthetase
Asera_RS11385	COG1309	transcriptional regulator
Asera_RS11400	COG1744	ABC transporter substrate-binding protein PnrA-like
Asera_RS11405	COG3845	ABC transporter
Asera_RS11410	COG4603	Belongs to the binding-protein-dependent transport system permease family
Asera_RS11415	COG1079	Belongs to the binding-protein-dependent transport system permease family
Asera_RS11430	COG0542	response to heat
Asera_RS11435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Asera_RS11435	COG0662	Cupin 2, conserved barrel domain protein
Asera_RS11445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_RS11465	COG2124	cytochrome p450
Asera_RS11520	COG2018	Roadblock/LC7 domain
Asera_RS11545	COG4166	transmembrane transport
Asera_RS11555	COG4166	transmembrane transport
Asera_RS11580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Asera_RS11610	COG2171	N-acyltransferase activity
Asera_RS11635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asera_RS11640	COG1611	Belongs to the LOG family
Asera_RS11650	COG0702	epimerase
Asera_RS11665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Asera_RS11675	COG0519	Catalyzes the synthesis of GMP from XMP
Asera_RS11685	COG1024	Enoyl-CoA hydratase
Asera_RS11700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Asera_RS11705	COG0657	acetylesterase activity
Asera_RS11720	COG2197	response regulator
Asera_RS11745	COG0297	glycogen (starch) synthase activity
Asera_RS11780	COG1657	PFAM Prenyltransferase squalene oxidase
Asera_RS11790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Asera_RS11800	COG1562	ergosterol biosynthetic process
Asera_RS11805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Asera_RS11810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Asera_RS11845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Asera_RS11855	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Asera_RS11890	COG3480	Lon protease (S16) C-terminal proteolytic domain
Asera_RS11895	COG1615	UPF0182 protein
Asera_RS11935	COG2186	Transcriptional regulator
Asera_RS11950	COG2226	methyltransferase
Asera_RS11965	COG0154	amidase activity
Asera_RS11980	COG2226	methyltransferase
Asera_RS12015	COG0488	(ABC) transporter
Asera_RS12025	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asera_RS12040	COG4585	Histidine kinase
Asera_RS12045	COG2197	response regulator
Asera_RS12065	COG2226	methyltransferase
Asera_RS12080	COG1653	transport
Asera_RS12090	COG1175	transmembrane transport
Asera_RS12120	COG1695	Transcriptional regulator
Asera_RS12165	COG1742	UPF0060 membrane protein
Asera_RS12175	COG3345	alpha-galactosidase
Asera_RS12185	COG0424	maF-like protein
Asera_RS12240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Asera_RS12245	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_RS12245	COG3848	Pyruvate phosphate dikinase
Asera_RS12265	COG1302	Protein conserved in bacteria
Asera_RS12290	COG0483	inositol monophosphate 1-phosphatase activity
Asera_RS12330	COG1832	CoA-binding protein
Asera_RS12335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Asera_RS12355	COG1216	Glycosyl transferase, family 2
Asera_RS12365	COG2267	carboxylic ester hydrolase activity
Asera_RS12400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_RS12410	COG2267	carboxylic ester hydrolase activity
Asera_RS12430	COG0438	transferase activity, transferring glycosyl groups
Asera_RS12440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_RS12460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Asera_RS12490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Asera_RS12495	COG2835	tetraacyldisaccharide 4'-kinase activity
Asera_RS12510	COG1482	cell wall glycoprotein biosynthetic process
Asera_RS12530	COG2124	cytochrome p450
Asera_RS12555	COG1131	(ABC) transporter
Asera_RS12575	COG1309	transcriptional regulator
Asera_RS12585	COG4585	Histidine kinase
Asera_RS12590	COG0586	Pfam SNARE associated Golgi protein
Asera_RS12615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Asera_RS12620	COG1595	DNA-templated transcription, initiation
Asera_RS12625	COG1595	DNA-templated transcription, initiation
Asera_RS12660	COG3973	AAA domain
Asera_RS12690	COG2197	response regulator
Asera_RS12695	COG4941	Belongs to the sigma-70 factor family
Asera_RS12700	COG3795	YCII-related domain
Asera_RS12770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Asera_RS12790	COG1053	succinate dehydrogenase
Asera_RS12810	COG1595	DNA-templated transcription, initiation
Asera_RS12850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Asera_RS12860	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asera_RS12875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_RS12880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_RS12890	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Asera_RS12920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_RS12960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asera_RS12960	COG1017	nitric oxide dioxygenase activity
Asera_RS12975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Asera_RS13000	COG0596	Alpha beta hydrolase
Asera_RS13015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asera_RS13030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asera_RS13045	COG0640	Transcriptional regulator
Asera_RS13095	COG0604	alcohol dehydrogenase
Asera_RS13095	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS13095	COG3321	synthase
Asera_RS13105	COG0531	amino acid
Asera_RS13115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Asera_RS13175	COG3254	rhamnose metabolic process
Asera_RS13210	COG0071	Belongs to the small heat shock protein (HSP20) family
Asera_RS13295	COG4821	SIS domain
Asera_RS13320	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS13340	COG3655	Transcriptional regulator
Asera_RS13350	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS13350	COG3321	synthase
Asera_RS13350	COG0604	alcohol dehydrogenase
Asera_RS13370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asera_RS13370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_RS13420	COG0789	Transcriptional regulator
Asera_RS13425	COG0604	alcohol dehydrogenase
Asera_RS13445	COG1131	(ABC) transporter
Asera_RS13475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asera_RS13505	COG0346	lactoylglutathione lyase activity
Asera_RS13515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asera_RS13520	COG0129	dihydroxy-acid dehydratase activity
Asera_RS13525	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Asera_RS13530	COG3387	PFAM Glycoside hydrolase 15-related
Asera_RS13540	COG1609	Transcriptional regulator
Asera_RS13550	COG1733	regulation of RNA biosynthetic process
Asera_RS13555	COG0604	alcohol dehydrogenase
Asera_RS13555	COG3321	synthase
Asera_RS13565	COG1522	sequence-specific DNA binding
Asera_RS13585	COG1122	ATPase activity
Asera_RS13590	COG1725	Transcriptional regulator
Asera_RS13640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asera_RS13650	COG0154	amidase activity
Asera_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS13680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asera_RS13685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Asera_RS13690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Asera_RS13700	COG0783	Belongs to the Dps family
Asera_RS13705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asera_RS13705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asera_RS13740	COG0583	DNA-binding transcription factor activity
Asera_RS13760	COG1233	COG1233 Phytoene dehydrogenase and related
Asera_RS13770	COG0142	geranyltranstransferase activity
Asera_RS13825	COG0431	NADPH-dependent FMN reductase
Asera_RS13830	COG0477	Major facilitator Superfamily
Asera_RS13835	COG0789	Transcriptional regulator
Asera_RS13840	COG2267	carboxylic ester hydrolase activity
Asera_RS13850	COG0477	Major facilitator Superfamily
Asera_RS13870	COG0549	Belongs to the carbamate kinase family
Asera_RS13885	COG1063	alcohol dehydrogenase
Asera_RS13920	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Asera_RS13975	COG2409	Drug exporters of the RND superfamily
Asera_RS14005	COG0477	Major facilitator Superfamily
Asera_RS14090	COG0739	heme binding
Asera_RS14110	COG2272	Belongs to the type-B carboxylesterase lipase family
Asera_RS14120	COG2318	DinB family
Asera_RS14125	COG2814	Major facilitator Superfamily
Asera_RS14130	COG0402	S-adenosylhomocysteine deaminase activity
Asera_RS14165	COG1802	Transcriptional regulator
Asera_RS14170	COG0667	Aldo Keto reductase
Asera_RS14180	COG0456	acetyltransferase
Asera_RS14250	COG0583	DNA-binding transcription factor activity
Asera_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS14280	COG1733	regulation of RNA biosynthetic process
Asera_RS14315	COG0583	DNA-binding transcription factor activity
Asera_RS14355	COG1280	lysine exporter protein (LysE YggA)
Asera_RS14370	COG2353	YceI-like domain
Asera_RS14375	COG1335	isochorismatase
Asera_RS14390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Asera_RS14400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_RS14470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_RS14490	COG1309	transcriptional regulator
Asera_RS14495	COG1063	alcohol dehydrogenase
Asera_RS14505	COG2814	Major facilitator Superfamily
Asera_RS14540	COG2304	oxidoreductase activity
Asera_RS14710	COG1278	Cold shock
Asera_RS14715	COG1505	serine-type exopeptidase activity
Asera_RS14725	COG1228	amidohydrolase
Asera_RS14755	COG1063	alcohol dehydrogenase
Asera_RS14765	COG2508	Transcriptional regulator
Asera_RS14765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Asera_RS14770	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS14795	COG0444	Belongs to the ABC transporter superfamily
Asera_RS14855	COG2211	Major facilitator Superfamily
Asera_RS14860	COG0076	glutamate decarboxylase activity
Asera_RS14955	COG0612	Peptidase, M16
Asera_RS15035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Asera_RS15045	COG1846	Transcriptional regulator
Asera_RS15110	COG3387	PFAM Glycoside hydrolase 15-related
Asera_RS15115	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS15125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_RS15140	COG1846	Transcriptional regulator
Asera_RS15140	COG1940	carbohydrate kinase activity
Asera_RS15165	COG1846	Transcriptional regulator
Asera_RS15165	COG1940	carbohydrate kinase activity
Asera_RS15175	COG1940	carbohydrate kinase activity
Asera_RS15180	COG1653	transport
Asera_RS15185	COG1175	transmembrane transport
Asera_RS15190	COG0395	ABC-type sugar transport system, permease component
Asera_RS15200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Asera_RS15235	COG0483	inositol monophosphate 1-phosphatase activity
Asera_RS15255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Asera_RS15270	COG1595	DNA-templated transcription, initiation
Asera_RS15275	COG5662	AntiSigma factor
Asera_RS15280	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Asera_RS15285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Asera_RS15290	COG1174	glycine betaine transport
Asera_RS15300	COG1174	glycine betaine transport
Asera_RS15315	COG3384	dioxygenase
Asera_RS15340	COG0667	Aldo Keto reductase
Asera_RS15360	COG0542	response to heat
Asera_RS15375	COG0175	sulfate reduction
Asera_RS15390	COG1597	lipid kinase activity
Asera_RS15400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Asera_RS15405	COG1335	isochorismatase
Asera_RS15410	COG0740	serine-type endopeptidase activity
Asera_RS15415	COG0740	serine-type endopeptidase activity
Asera_RS15420	COG1396	sequence-specific DNA binding
Asera_RS15425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Asera_RS15435	COG0697	spore germination
Asera_RS15440	COG0300	oxidoreductase activity
Asera_RS15450	COG0737	Belongs to the 5'-nucleotidase family
Asera_RS15550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_RS15555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asera_RS15590	COG2239	Acts as a magnesium transporter
Asera_RS15610	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS15670	COG0613	PHP domain protein
Asera_RS15675	COG2095	MarC family integral membrane protein
Asera_RS15705	COG1309	transcriptional regulator
Asera_RS15710	COG0702	epimerase
Asera_RS15730	COG0513	Belongs to the DEAD box helicase family
Asera_RS15775	COG1366	Belongs to the anti-sigma-factor antagonist family
Asera_RS15780	COG0583	DNA-binding transcription factor activity
Asera_RS15795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Asera_RS15800	COG1609	Transcriptional regulator
Asera_RS15820	COG0395	ABC-type sugar transport system, permease component
Asera_RS15840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Asera_RS15855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Asera_RS15870	COG2337	Toxic component of a toxin-antitoxin (TA) module
Asera_RS15880	COG2223	nitrite transmembrane transporter activity
Asera_RS15885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Asera_RS15895	COG4221	oxidoreductase activity
Asera_RS15910	COG0583	DNA-binding transcription factor activity
Asera_RS15915	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Asera_RS15925	COG0366	Alpha amylase catalytic
Asera_RS15940	COG0668	transmembrane transport
Asera_RS15970	COG0154	amidase activity
Asera_RS15980	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Asera_RS15990	COG1733	regulation of RNA biosynthetic process
Asera_RS16005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Asera_RS16035	COG1136	(ABC) transporter
Asera_RS16065	COG1051	belongs to the nudix hydrolase family
Asera_RS16090	COG1530	ribonuclease E activity
Asera_RS16095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Asera_RS16100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Asera_RS16105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Asera_RS16135	COG0747	negative chemotaxis
Asera_RS16140	COG0601	transmembrane transport
Asera_RS16145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS16150	COG0444	Belongs to the ABC transporter superfamily
Asera_RS16155	COG4608	Belongs to the ABC transporter superfamily
Asera_RS16170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asera_RS16175	COG1929	Belongs to the glycerate kinase type-1 family
Asera_RS16185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_RS16190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Asera_RS16215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Asera_RS16265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Asera_RS16270	COG1051	belongs to the nudix hydrolase family
Asera_RS16280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Asera_RS16290	COG2124	cytochrome p450
Asera_RS16300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asera_RS16320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_RS16325	COG0501	Belongs to the peptidase M48B family
Asera_RS16330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Asera_RS16330	COG2755	lipolytic protein G-D-S-L family
Asera_RS16335	COG0438	transferase activity, transferring glycosyl groups
Asera_RS16385	COG1940	carbohydrate kinase activity
Asera_RS16400	COG0583	DNA-binding transcription factor activity
Asera_RS16405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Asera_RS16430	COG0156	8-amino-7-oxononanoate synthase activity
Asera_RS16435	COG1063	alcohol dehydrogenase
Asera_RS16440	COG0028	Belongs to the TPP enzyme family
Asera_RS16465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_RS16480	COG2072	flavoprotein involved in K transport
Asera_RS16520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asera_RS16540	COG0205	6-phosphofructokinase activity
Asera_RS16550	COG0517	IMP dehydrogenase activity
Asera_RS16550	COG4175	Glycine betaine
Asera_RS16565	COG1309	transcriptional regulator
Asera_RS16570	COG0477	Major facilitator Superfamily
Asera_RS16575	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Asera_RS16580	COG3511	phospholipase C
Asera_RS16590	COG3511	phospholipase C
Asera_RS16610	COG0667	Aldo Keto reductase
Asera_RS16620	COG1733	regulation of RNA biosynthetic process
Asera_RS16625	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Asera_RS16630	COG0515	serine threonine protein kinase
Asera_RS16630	COG2815	serine threonine protein kinase
Asera_RS16635	COG2226	methyltransferase
Asera_RS16660	COG1609	Transcriptional regulator
Asera_RS16670	COG1196	nuclear chromosome segregation
Asera_RS16675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Asera_RS16680	COG3537	Alpha-1,2-mannosidase
Asera_RS16685	COG0252	asparaginase activity
Asera_RS16695	COG1104	cysteine desulfurase activity
Asera_RS16700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Asera_RS16720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Asera_RS16730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Asera_RS16740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Asera_RS16745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Asera_RS16755	COG0789	Transcriptional regulator
Asera_RS16775	COG0737	Belongs to the 5'-nucleotidase family
Asera_RS16785	COG0745	RESPONSE REGULATOR receiver
Asera_RS16790	COG5002	protein histidine kinase activity
Asera_RS16795	COG2358	TRAP transporter, solute receptor (TAXI family
Asera_RS16810	COG1643	Atp-dependent helicase
Asera_RS16830	COG4221	oxidoreductase activity
Asera_RS16840	COG2072	flavoprotein involved in K transport
Asera_RS16860	COG0183	Belongs to the thiolase family
Asera_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS16875	COG1309	transcriptional regulator
Asera_RS16885	COG1960	acyl-CoA dehydrogenase activity
Asera_RS16905	COG1309	transcriptional regulator
Asera_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS16930	COG3552	Protein containing von Willebrand factor type A (VWA) domain
Asera_RS16935	COG0714	Associated with various cellular activities
Asera_RS16960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_RS16985	COG3629	intracellular signal transduction
Asera_RS16985	COG3903	Transcriptional regulator
Asera_RS16995	COG0142	geranyltranstransferase activity
Asera_RS17035	COG0583	DNA-binding transcription factor activity
Asera_RS17060	COG0137	argininosuccinate synthase activity
Asera_RS17070	COG5434	Belongs to the glycosyl hydrolase 28 family
Asera_RS17070	COG4632	Exopolysaccharide biosynthesis protein
Asera_RS17075	COG3959	Transketolase, thiamine diphosphate binding domain
Asera_RS17085	COG1937	Protein conserved in bacteria
Asera_RS17100	COG1122	ATPase activity
Asera_RS17105	COG4721	ABC-type cobalt transport system, permease component
Asera_RS17155	COG0423	glycine-tRNA ligase activity
Asera_RS17200	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_RS17200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asera_RS17230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Asera_RS17255	COG0277	FAD linked oxidase domain protein
Asera_RS17255	COG0247	lactate metabolic process
Asera_RS17290	COG1132	(ABC) transporter
Asera_RS17295	COG1846	Transcriptional regulator
Asera_RS17300	COG0358	DNA primase activity
Asera_RS17315	COG1131	(ABC) transporter
Asera_RS17365	COG0667	Aldo Keto reductase
Asera_RS17405	COG1595	DNA-templated transcription, initiation
Asera_RS17420	COG3938	Belongs to the proline racemase family
Asera_RS17425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asera_RS17455	COG0018	arginyl-trna synthetase
Asera_RS17480	COG1846	Transcriptional regulator
Asera_RS17505	COG0714	Associated with various cellular activities
Asera_RS17540	COG0302	gtp cyclohydrolase
Asera_RS17580	COG2205	protein histidine kinase activity
Asera_RS17615	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_RS17620	COG1920	GTP binding
Asera_RS17630	COG3345	alpha-galactosidase
Asera_RS17655	COG1121	(ABC) transporter
Asera_RS17675	COG1199	ATP-dependent helicase activity
Asera_RS17675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Asera_RS17685	COG1116	anion transmembrane transporter activity
Asera_RS17800	COG4974	Belongs to the 'phage' integrase family
Asera_RS17850	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
Asera_RS17855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Asera_RS17870	COG0642	Histidine kinase
Asera_RS17900	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Asera_RS17905	COG2814	Major facilitator Superfamily
Asera_RS17915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Asera_RS17920	COG2755	lipolytic protein G-D-S-L family
Asera_RS17920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Asera_RS17940	COG2837	iron assimilation
Asera_RS17985	COG0477	Major facilitator Superfamily
Asera_RS18005	COG0395	ABC-type sugar transport system, permease component
Asera_RS18010	COG1175	transmembrane transport
Asera_RS18035	COG4122	O-methyltransferase activity
Asera_RS18040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Asera_RS18040	COG0512	Glutamine amidotransferase of anthranilate synthase
Asera_RS18045	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS18080	COG0697	spore germination
Asera_RS18085	COG1846	Transcriptional regulator
Asera_RS18100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Asera_RS18110	COG0017	Asparaginyl-tRNA synthetase
Asera_RS18115	COG0321	lipoyl(octanoyl) transferase activity
Asera_RS18125	COG1134	teichoic acid transport
Asera_RS18140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Asera_RS18145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Asera_RS18155	COG0384	phenazine biosynthesis protein PhzF
Asera_RS18165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Asera_RS18180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Asera_RS18195	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Asera_RS18200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Asera_RS18210	COG0667	Aldo Keto reductase
Asera_RS18215	COG1609	Transcriptional regulator
Asera_RS18240	COG3119	arylsulfatase activity
Asera_RS18260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asera_RS18265	COG0586	Pfam SNARE associated Golgi protein
Asera_RS18305	COG0740	serine-type endopeptidase activity
Asera_RS18320	COG1063	alcohol dehydrogenase
Asera_RS18335	COG0542	response to heat
Asera_RS18345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Asera_RS18360	COG1573	uracil-dna glycosylase
Asera_RS18365	COG1620	l-lactate permease
Asera_RS18390	COG1609	Transcriptional regulator
Asera_RS18400	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_RS18405	COG2271	Major facilitator Superfamily
Asera_RS18410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_RS18415	COG1024	Enoyl-CoA hydratase
Asera_RS18430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Asera_RS18495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS18660	COG0582	viral genome integration into host DNA
Asera_RS18695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS18760	COG0582	viral genome integration into host DNA
Asera_RS18795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS18855	COG0582	viral genome integration into host DNA
Asera_RS18895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS18960	COG0582	viral genome integration into host DNA
Asera_RS18970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Asera_RS18980	COG2314	TM2 domain
Asera_RS18990	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS19000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Asera_RS19005	COG1414	Transcriptional regulator
Asera_RS19025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Asera_RS19035	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Asera_RS19040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Asera_RS19040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Asera_RS19045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Asera_RS19050	COG0174	glutamine synthetase
Asera_RS19060	COG0442	prolyl-tRNA aminoacylation
Asera_RS19085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Asera_RS19095	COG0277	FAD linked oxidase domain protein
Asera_RS19100	COG0247	lactate metabolic process
Asera_RS19105	COG2321	neutral zinc metallopeptidase
Asera_RS19115	COG1757	Na H antiporter
Asera_RS19125	COG2235	arginine
Asera_RS19140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Asera_RS19145	COG3469	chitinase activity
Asera_RS19165	COG0410	ABC transporter
Asera_RS19195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asera_RS19230	COG0776	regulation of translation
Asera_RS19235	COG1741	Belongs to the pirin family
Asera_RS19280	COG3189	MarR family transcriptional regulator
Asera_RS19285	COG3876	Protein conserved in bacteria
Asera_RS19290	COG1737	Transcriptional regulator
Asera_RS19300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_RS19315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Asera_RS19340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Asera_RS19340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Asera_RS19350	COG0018	arginyl-trna synthetase
Asera_RS19355	COG0019	diaminopimelate decarboxylase activity
Asera_RS19360	COG0460	homoserine dehydrogenase
Asera_RS19365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Asera_RS19385	COG0745	RESPONSE REGULATOR receiver
Asera_RS19390	COG2205	protein histidine kinase activity
Asera_RS19400	COG0083	homoserine kinase activity
Asera_RS19410	COG5006	permease, DMT superfamily
Asera_RS19415	COG1063	alcohol dehydrogenase
Asera_RS19435	COG0254	rRNA binding
Asera_RS19440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Asera_RS19450	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_RS19455	COG0009	L-threonylcarbamoyladenylate synthase
Asera_RS19460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Asera_RS19475	COG0356	it plays a direct role in the translocation of protons across the membrane
Asera_RS19480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Asera_RS19485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Asera_RS19490	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Asera_RS19495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Asera_RS19500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Asera_RS19505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Asera_RS19510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Asera_RS19530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asera_RS19560	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_RS19570	COG3285	dna ligase
Asera_RS19570	COG1793	dna ligase
Asera_RS19590	COG1674	ftsk spoiiie
Asera_RS19650	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Asera_RS19695	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS19700	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_RS19725	COG2267	carboxylic ester hydrolase activity
Asera_RS19730	COG2267	carboxylic ester hydrolase activity
Asera_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS19745	COG0123	including yeast histone deacetylase and acetoin utilization protein
Asera_RS19770	COG0501	Belongs to the peptidase M48B family
Asera_RS19775	COG1490	D-aminoacyl-tRNA deacylase activity
Asera_RS19780	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_RS19790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_RS19795	COG2313	pseudouridylate synthase activity
Asera_RS19825	COG0483	inositol monophosphate 1-phosphatase activity
Asera_RS19850	COG0756	dUTP diphosphatase activity
Asera_RS19880	COG0569	domain protein
Asera_RS19885	COG0531	amino acid
Asera_RS19905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asera_RS19910	COG1940	carbohydrate kinase activity
Asera_RS19915	COG4213	ABC transporter substrate-binding protein
Asera_RS19925	COG4214	carbohydrate transport
Asera_RS19930	COG4608	Belongs to the ABC transporter superfamily
Asera_RS19935	COG0444	Belongs to the ABC transporter superfamily
Asera_RS19940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS19945	COG0601	transmembrane transport
Asera_RS19950	COG0747	negative chemotaxis
Asera_RS19955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_RS19960	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Asera_RS19965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Asera_RS19980	COG3537	Alpha-1,2-mannosidase
Asera_RS20005	COG0745	RESPONSE REGULATOR receiver
Asera_RS20010	COG2205	protein histidine kinase activity
Asera_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS20045	COG0604	alcohol dehydrogenase
Asera_RS20045	COG3321	synthase
Asera_RS20050	COG1309	transcriptional regulator
Asera_RS20055	COG0477	Major facilitator Superfamily
Asera_RS20080	COG1250	3-hydroxyacyl-CoA dehydrogenase
Asera_RS20080	COG1024	Enoyl-CoA hydratase
Asera_RS20085	COG0183	Belongs to the thiolase family
Asera_RS20090	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Asera_RS20095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_RS20110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Asera_RS20115	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Asera_RS20120	COG3253	May function as heme-dependent peroxidase
Asera_RS20130	COG1940	carbohydrate kinase activity
Asera_RS20145	COG3579	cysteine-type endopeptidase activity
Asera_RS20160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Asera_RS20175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Asera_RS20185	COG3962	Belongs to the TPP enzyme family
Asera_RS20190	COG3718	enzyme involved in inositol metabolism
Asera_RS20205	COG1082	Xylose isomerase domain protein TIM barrel
Asera_RS20210	COG0673	inositol 2-dehydrogenase activity
Asera_RS20215	COG2188	Transcriptional regulator
Asera_RS20220	COG0560	Phosphoserine phosphatase
Asera_RS20250	COG1643	Atp-dependent helicase
Asera_RS20265	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Asera_RS20270	COG0412	Dienelactone hydrolase
Asera_RS20300	COG0006	proline dipeptidase activity
Asera_RS20320	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS20330	COG1960	acyl-CoA dehydrogenase activity
Asera_RS20350	COG0747	negative chemotaxis
Asera_RS20355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS20360	COG0601	transmembrane transport
Asera_RS20375	COG0596	Alpha beta hydrolase
Asera_RS20410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asera_RS20425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_RS20435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Asera_RS20450	COG0006	proline dipeptidase activity
Asera_RS20460	COG1511	domain protein
Asera_RS20465	COG1136	(ABC) transporter
Asera_RS20475	COG1309	transcriptional regulator
Asera_RS20485	COG1119	ATPase activity
Asera_RS20490	COG3903	Transcriptional regulator
Asera_RS20490	COG3629	intracellular signal transduction
Asera_RS20500	COG0583	DNA-binding transcription factor activity
Asera_RS20505	COG0667	Aldo Keto reductase
Asera_RS20510	COG0823	Involved in the tonB-independent uptake of proteins
Asera_RS20525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asera_RS20530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Asera_RS20540	COG1595	DNA-templated transcription, initiation
Asera_RS20560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Asera_RS20590	COG0697	spore germination
Asera_RS20615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Asera_RS20640	COG0714	Associated with various cellular activities
Asera_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS20660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Asera_RS20665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Asera_RS20680	COG0791	NLP P60 protein
Asera_RS20680	COG3883	PFAM NLP P60 protein
Asera_RS20705	COG1653	transport
Asera_RS20710	COG1175	transmembrane transport
Asera_RS20715	COG0395	ABC-type sugar transport system, permease component
Asera_RS20730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Asera_RS20735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Asera_RS20740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_RS20755	COG4221	oxidoreductase activity
Asera_RS20775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Asera_RS20780	COG1733	regulation of RNA biosynthetic process
Asera_RS20785	COG0702	epimerase
Asera_RS20790	COG0402	S-adenosylhomocysteine deaminase activity
Asera_RS20815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asera_RS20835	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Asera_RS20850	COG2249	NAD(P)H dehydrogenase (quinone) activity
Asera_RS20860	COG1609	Transcriptional regulator
Asera_RS20870	COG2182	Extracellular solute-binding protein
Asera_RS20875	COG1175	transmembrane transport
Asera_RS20880	COG0395	ABC-type sugar transport system, permease component
Asera_RS20890	COG0443	Heat shock 70 kDa protein
Asera_RS20925	COG1175	transmembrane transport
Asera_RS20960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_RS20965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_RS20995	COG0640	Transcriptional regulator
Asera_RS21035	COG3328	transposase activity
Asera_RS21065	COG3469	chitinase activity
Asera_RS21075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Asera_RS21100	COG1595	DNA-templated transcription, initiation
Asera_RS21110	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Asera_RS21140	COG2271	Major facilitator Superfamily
Asera_RS21145	COG1234	tRNA 3'-trailer cleavage
Asera_RS21155	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_RS21190	COG2197	response regulator
Asera_RS21215	COG1716	ATPase activity
Asera_RS21220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Asera_RS21235	COG1070	Carbohydrate kinase
Asera_RS21255	COG2208	phosphoserine phosphatase activity
Asera_RS21280	COG0702	epimerase
Asera_RS21295	COG3795	YCII-related domain
Asera_RS21300	COG4941	Belongs to the sigma-70 factor family
Asera_RS21325	COG3629	intracellular signal transduction
Asera_RS21325	COG3903	Transcriptional regulator
Asera_RS21370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Asera_RS21375	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Asera_RS21415	COG2815	serine threonine protein kinase
Asera_RS21415	COG0515	serine threonine protein kinase
Asera_RS21485	COG0667	Aldo Keto reductase
Asera_RS21490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_RS21495	COG0588	phosphoglycerate mutase activity
Asera_RS21515	COG0215	cysteine-tRNA ligase activity
Asera_RS21540	COG0646	methionine synthase
Asera_RS21540	COG1410	methionine synthase
Asera_RS21555	COG0546	phosphoglycolate phosphatase activity
Asera_RS21575	COG1476	TRANSCRIPTIONal
Asera_RS21580	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
Asera_RS21590	COG0577	efflux transmembrane transporter activity
Asera_RS21590	COG1136	(ABC) transporter
Asera_RS21595	COG1136	(ABC) transporter
Asera_RS21600	COG2197	response regulator
Asera_RS21605	COG4585	Histidine kinase
Asera_RS21615	COG0517	IMP dehydrogenase activity
Asera_RS21615	COG1994	Peptidase M50
Asera_RS21625	COG1222	aaa ATPase
Asera_RS21635	COG4122	O-methyltransferase activity
Asera_RS21650	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asera_RS21655	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asera_RS21660	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Asera_RS21680	COG2378	regulation of single-species biofilm formation
Asera_RS21685	COG2378	regulation of single-species biofilm formation
Asera_RS21695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Asera_RS21700	COG0805	protein transport
Asera_RS21720	COG2318	DinB family
Asera_RS21730	COG0745	RESPONSE REGULATOR receiver
Asera_RS21740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asera_RS21740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Asera_RS21745	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Asera_RS21755	COG0140	phosphoribosyl-ATP diphosphatase activity
Asera_RS21760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Asera_RS21775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Asera_RS21780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Asera_RS21785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Asera_RS21790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Asera_RS21795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Asera_RS21800	COG0072	phenylalanine-tRNA ligase activity
Asera_RS21800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Asera_RS21820	COG1215	transferase activity, transferring glycosyl groups
Asera_RS21825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Asera_RS21830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Asera_RS21835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Asera_RS21840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Asera_RS21845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Asera_RS21855	COG0165	Argininosuccinate lyase
Asera_RS21860	COG2094	Belongs to the DNA glycosylase MPG family
Asera_RS21865	COG0789	Transcriptional regulator
Asera_RS21875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Asera_RS21900	COG0647	UMP catabolic process
Asera_RS21925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Asera_RS21930	COG0497	DNA recombination
Asera_RS21950	COG0297	glycogen (starch) synthase activity
Asera_RS21960	COG0504	CTP synthase activity
Asera_RS21965	COG0494	nUDIX hydrolase
Asera_RS21985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Asera_RS21990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Asera_RS22005	COG4608	Belongs to the ABC transporter superfamily
Asera_RS22010	COG0444	Belongs to the ABC transporter superfamily
Asera_RS22015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS22025	COG4166	transmembrane transport
Asera_RS22030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Asera_RS22035	COG1160	GTP binding
Asera_RS22050	COG0583	DNA-binding transcription factor activity
Asera_RS22060	COG1053	succinate dehydrogenase
Asera_RS22065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Asera_RS22070	COG1846	Transcriptional regulator
Asera_RS22080	COG3201	nicotinamide mononucleotide transporter
Asera_RS22095	COG1191	sigma factor activity
Asera_RS22105	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS22110	COG1063	alcohol dehydrogenase
Asera_RS22115	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS22125	COG1414	Transcriptional regulator
Asera_RS22135	COG2814	Major facilitator Superfamily
Asera_RS22140	COG3408	Glycogen debranching enzyme
Asera_RS22155	COG3250	beta-galactosidase activity
Asera_RS22170	COG0254	rRNA binding
Asera_RS22180	COG1739	Uncharacterized protein family UPF0029
Asera_RS22185	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Asera_RS22200	COG0442	prolyl-tRNA aminoacylation
Asera_RS22210	COG2197	response regulator
Asera_RS22260	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_RS22275	COG0583	DNA-binding transcription factor activity
Asera_RS22295	COG0667	Aldo Keto reductase
Asera_RS22315	COG0702	epimerase
Asera_RS22375	COG2182	Extracellular solute-binding protein
Asera_RS22385	COG0395	ABC-type sugar transport system, permease component
Asera_RS22390	COG3842	ATPase activity
Asera_RS22395	COG1733	regulation of RNA biosynthetic process
Asera_RS22400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Asera_RS22410	COG0456	acetyltransferase
Asera_RS22415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Asera_RS22425	COG0725	ABC transporter, periplasmic molybdate-binding protein
Asera_RS22450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_RS22465	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Asera_RS22490	COG1191	sigma factor activity
Asera_RS22515	COG1554	hydrolase, family 65, central catalytic
Asera_RS22525	COG1960	acyl-CoA dehydrogenase activity
Asera_RS22535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Asera_RS22550	COG1960	acyl-CoA dehydrogenase activity
Asera_RS22570	COG0406	alpha-ribazole phosphatase activity
Asera_RS22580	COG0604	alcohol dehydrogenase
Asera_RS22590	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Asera_RS22595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_RS22625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Asera_RS22640	COG1752	Esterase of the alpha-beta hydrolase superfamily
Asera_RS22650	COG1435	thymidine kinase activity
Asera_RS22655	COG2270	Major facilitator Superfamily
Asera_RS22665	COG0443	Heat shock 70 kDa protein
Asera_RS22695	COG2197	response regulator
Asera_RS22705	COG1271	oxidase subunit
Asera_RS22710	COG1294	oxidase, subunit
Asera_RS22715	COG4988	ABC transporter
Asera_RS22720	COG1132	(ABC) transporter
Asera_RS22760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Asera_RS22780	COG4974	Belongs to the 'phage' integrase family
Asera_RS22790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Asera_RS22795	COG1132	(ABC) transporter
Asera_RS22810	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_RS22815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_RS22830	COG2197	response regulator
Asera_RS22840	COG4941	Belongs to the sigma-70 factor family
Asera_RS22845	COG3795	YCII-related domain
Asera_RS22855	COG2814	Major facilitator Superfamily
Asera_RS22870	COG0477	Major facilitator Superfamily
Asera_RS22885	COG2318	DinB family
Asera_RS22910	COG2249	NAD(P)H dehydrogenase (quinone) activity
Asera_RS23005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Asera_RS23005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Asera_RS23025	COG1716	ATPase activity
Asera_RS23105	COG1051	belongs to the nudix hydrolase family
Asera_RS23110	COG0105	UTP biosynthetic process
Asera_RS23160	COG2188	Transcriptional regulator
Asera_RS23165	COG4821	SIS domain
Asera_RS23190	COG1073	alpha beta
Asera_RS23200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_RS23215	COG2814	Major facilitator Superfamily
Asera_RS23230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Asera_RS23235	COG0242	peptide deformylase activity
Asera_RS23245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Asera_RS23255	COG1758	RNA polymerase activity
Asera_RS23260	COG0194	GDP metabolic process
Asera_RS23265	COG0194	GDP metabolic process
Asera_RS23270	COG0284	orotidine-5'-phosphate decarboxylase activity
Asera_RS23275	COG0167	dihydroorotate dehydrogenase activity
Asera_RS23285	COG0505	Belongs to the CarA family
Asera_RS23290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asera_RS23295	COG0540	Belongs to the ATCase OTCase family
Asera_RS23300	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Asera_RS23310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Asera_RS23315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Asera_RS23325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Asera_RS23330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Asera_RS23335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Asera_RS23340	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Asera_RS23365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Asera_RS23390	COG1461	Dihydroxyacetone kinase
Asera_RS23395	COG2376	Dihydroxyacetone kinase
Asera_RS23425	COG2197	response regulator
Asera_RS23430	COG4585	Histidine kinase
Asera_RS23440	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Asera_RS23445	COG0124	histidyl-tRNA synthetase
Asera_RS23465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Asera_RS23470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Asera_RS23475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Asera_RS23485	COG1862	Preprotein translocase
Asera_RS23490	COG2255	four-way junction helicase activity
Asera_RS23495	COG0632	four-way junction helicase activity
Asera_RS23500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Asera_RS23510	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Asera_RS23515	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Asera_RS23525	COG0438	transferase activity, transferring glycosyl groups
Asera_RS23530	COG1560	Kdo2-lipid A biosynthetic process
Asera_RS23555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asera_RS23565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_RS23570	COG2188	Transcriptional regulator
Asera_RS23580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Asera_RS23595	COG1695	Transcriptional regulator
Asera_RS23620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Asera_RS23630	COG2223	nitrite transmembrane transporter activity
Asera_RS23650	COG1940	carbohydrate kinase activity
Asera_RS23665	COG0446	pyridine nucleotide-disulphide oxidoreductase
Asera_RS23665	COG1902	pentaerythritol trinitrate reductase activity
Asera_RS23680	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_RS23705	COG3511	phospholipase C
Asera_RS23730	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS23735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asera_RS23740	COG0642	Histidine kinase
Asera_RS23750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_RS23770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_RS23775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Asera_RS23780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Asera_RS23815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_RS23820	COG1649	PFAM Uncharacterised BCR, COG1649
Asera_RS23825	COG1595	DNA-templated transcription, initiation
Asera_RS23840	COG1316	TRANSCRIPTIONal
Asera_RS23850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Asera_RS23860	COG3290	protein histidine kinase activity
Asera_RS23865	COG4565	transcriptional regulatory protein
Asera_RS23890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Asera_RS23915	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS23925	COG1653	transport
Asera_RS23930	COG1175	transmembrane transport
Asera_RS23945	COG4585	Histidine kinase
Asera_RS23950	COG2197	response regulator
Asera_RS23975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Asera_RS23980	COG3842	ATPase activity
Asera_RS23985	COG3022	response to hydroperoxide
Asera_RS23990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Asera_RS23995	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Asera_RS24025	COG1802	Transcriptional regulator
Asera_RS24035	COG3473	Maleate cis-trans isomerase
Asera_RS24040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Asera_RS24045	COG0154	amidase activity
Asera_RS24055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Asera_RS24070	COG0420	3'-5' exonuclease activity
Asera_RS24075	COG0419	ATPase involved in DNA repair
Asera_RS24100	COG1793	dna ligase
Asera_RS24110	COG0039	L-malate dehydrogenase activity
Asera_RS24115	COG1609	Transcriptional regulator
Asera_RS24130	COG1070	Carbohydrate kinase
Asera_RS24140	COG1175	transmembrane transport
Asera_RS24145	COG0395	ABC-type sugar transport system, permease component
Asera_RS24155	COG1765	OsmC-like protein
Asera_RS24165	COG4941	Belongs to the sigma-70 factor family
Asera_RS24180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Asera_RS24200	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS24210	COG1024	Enoyl-CoA hydratase
Asera_RS24240	COG0488	(ABC) transporter
Asera_RS24255	COG2151	metal-sulfur cluster biosynthetic enzyme
Asera_RS24260	COG0822	iron-sulfur transferase activity
Asera_RS24265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Asera_RS24270	COG0396	ATPase activity
Asera_RS24295	COG1612	heme a metabolic process
Asera_RS24305	COG1063	alcohol dehydrogenase
Asera_RS24310	COG3875	lactate racemase activity
Asera_RS24325	COG0109	protoheme IX farnesyltransferase activity
Asera_RS24335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Asera_RS24350	COG0363	glucosamine-6-phosphate deaminase activity
Asera_RS24360	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Asera_RS24375	COG0149	triose-phosphate isomerase activity
Asera_RS24380	COG0126	phosphoglycerate kinase activity
Asera_RS24385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Asera_RS24390	COG1481	regulation of sporulation
Asera_RS24400	COG1660	Displays ATPase and GTPase activities
Asera_RS24405	COG0322	excinuclease ABC activity
Asera_RS24420	COG1162	GTPase activity
Asera_RS24425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_RS24440	COG1217	gtp-binding protein TYPA
Asera_RS24460	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS24465	COG0791	NLP P60 protein
Asera_RS24475	COG2329	Antibiotic biosynthesis monooxygenase
Asera_RS24500	COG2197	response regulator
Asera_RS24505	COG4585	Histidine kinase
Asera_RS24515	COG1131	(ABC) transporter
Asera_RS24520	COG0237	dephospho-CoA kinase activity
Asera_RS24520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Asera_RS24545	COG2362	D-Aminopeptidase
Asera_RS24550	COG0531	amino acid
Asera_RS24565	COG0765	amino acid transport
Asera_RS24570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_RS24635	COG3345	alpha-galactosidase
Asera_RS24640	COG1946	Acyl-CoA thioesterase
Asera_RS24720	COG1802	Transcriptional regulator
Asera_RS24730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Asera_RS24735	COG3716	PTS system mannose fructose sorbose family IID component
Asera_RS24740	COG3715	PTS system
Asera_RS24750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Asera_RS24755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Asera_RS24765	COG1522	sequence-specific DNA binding
Asera_RS24775	COG0070	glutamate synthase
Asera_RS24775	COG0069	glutamate synthase activity
Asera_RS24775	COG0067	glutamate synthase
Asera_RS24800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Asera_RS24815	COG0133	tryptophan synthase activity
Asera_RS24835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Asera_RS24850	COG1132	(ABC) transporter
Asera_RS24855	COG1132	(ABC) transporter
Asera_RS24865	COG2364	Membrane
Asera_RS24870	COG0107	imidazoleglycerol-phosphate synthase activity
Asera_RS24875	COG0251	oxidation-reduction process
Asera_RS24880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Asera_RS24895	COG0131	Imidazoleglycerol-phosphate dehydratase
Asera_RS24900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Asera_RS24905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Asera_RS24910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Asera_RS24920	COG0587	DNA-directed DNA polymerase activity
Asera_RS24935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Asera_RS24940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Asera_RS24950	COG3599	regulation of cell shape
Asera_RS24960	COG1799	cell septum assembly
Asera_RS24965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Asera_RS24975	COG2318	DinB family
Asera_RS24980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Asera_RS24985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Asera_RS24990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asera_RS25000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Asera_RS25005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Asera_RS25015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Asera_RS25020	COG0768	penicillin binding
Asera_RS25030	COG0275	rRNA processing
Asera_RS25035	COG2001	Belongs to the MraZ family
Asera_RS25040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Asera_RS25045	COG3442	glutamine amidotransferase
Asera_RS25055	COG0495	leucyl-tRNA aminoacylation
Asera_RS25060	COG0714	Associated with various cellular activities
Asera_RS25080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Asera_RS25105	COG2124	cytochrome p450
Asera_RS25120	COG0587	DNA-directed DNA polymerase activity
Asera_RS25145	COG0339	signal peptide processing
Asera_RS25165	COG1309	transcriptional regulator
Asera_RS25185	COG0142	geranyltranstransferase activity
Asera_RS25205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asera_RS25210	COG1126	abc transporter atp-binding protein
Asera_RS25215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Asera_RS25220	COG0765	amino acid transport
Asera_RS25225	COG0765	amino acid transport
Asera_RS25230	COG0438	transferase activity, transferring glycosyl groups
Asera_RS25240	COG1418	mRNA catabolic process
Asera_RS25245	COG2137	regulation of response to DNA damage stimulus
Asera_RS25250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Asera_RS25270	COG1201	RNA secondary structure unwinding
Asera_RS25300	COG1842	Phage shock protein A
Asera_RS25305	COG1396	sequence-specific DNA binding
Asera_RS25310	COG1058	Belongs to the CinA family
Asera_RS25310	COG1546	Belongs to the CinA family
Asera_RS25315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Asera_RS25320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Asera_RS25335	COG0443	Heat shock 70 kDa protein
Asera_RS25340	COG1674	ftsk spoiiie
Asera_RS25365	COG3619	membrane
Asera_RS25370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Asera_RS25375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Asera_RS25380	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Asera_RS25400	COG3214	Protein conserved in bacteria
Asera_RS25415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Asera_RS25420	COG0612	Peptidase, M16
Asera_RS25425	COG1185	polyribonucleotide nucleotidyltransferase activity
Asera_RS25430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Asera_RS25440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Asera_RS25445	COG0477	Major facilitator Superfamily
Asera_RS25460	COG0534	Mate efflux family protein
Asera_RS25465	COG1234	tRNA 3'-trailer cleavage
Asera_RS25480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Asera_RS25485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Asera_RS25515	COG1522	sequence-specific DNA binding
Asera_RS25525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Asera_RS25540	COG0779	Required for maturation of 30S ribosomal subunits
Asera_RS25595	COG0514	ATP-dependent DNA helicase (RecQ)
Asera_RS25625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Asera_RS25640	COG0456	acetyltransferase
Asera_RS25645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Asera_RS25650	COG0750	zinc metalloprotease
Asera_RS25665	COG2076	Multidrug Resistance protein
Asera_RS25675	COG0277	FAD linked oxidase domain protein
Asera_RS25705	COG2146	nitrite reductase [NAD(P)H] activity
Asera_RS25705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Asera_RS25720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Asera_RS25725	COG0575	Belongs to the CDS family
Asera_RS25730	COG0233	cytoplasmic translational termination
Asera_RS25735	COG0528	UMP kinase activity
Asera_RS25740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Asera_RS25745	COG0052	Belongs to the universal ribosomal protein uS2 family
Asera_RS25780	COG4974	Belongs to the 'phage' integrase family
Asera_RS25795	COG0792	nuclease activity
Asera_RS25810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Asera_RS25815	COG0681	Belongs to the peptidase S26 family
Asera_RS25820	COG0335	large ribosomal subunit rRNA binding
Asera_RS25825	COG0336	Belongs to the RNA methyltransferase TrmD family
Asera_RS25830	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Asera_RS25835	COG1837	Belongs to the UPF0109 family
Asera_RS25840	COG0228	four-way junction DNA binding
Asera_RS25855	COG4608	Belongs to the ABC transporter superfamily
Asera_RS25860	COG0444	Belongs to the ABC transporter superfamily
Asera_RS25870	COG4166	transmembrane transport
Asera_RS25875	COG0601	transmembrane transport
Asera_RS25880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS25890	COG0596	Alpha beta hydrolase
Asera_RS25900	COG0442	prolyl-tRNA aminoacylation
Asera_RS25950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Asera_RS25975	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Asera_RS25990	COG0653	protein targeting
Asera_RS26020	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS26030	COG1011	Hydrolase
Asera_RS26045	COG1254	Belongs to the acylphosphatase family
Asera_RS26050	COG3548	integral membrane protein
Asera_RS26055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Asera_RS26065	COG0571	ribonuclease III activity
Asera_RS26070	COG0416	fatty acid biosynthetic process
Asera_RS26075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Asera_RS26090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Asera_RS26095	COG0742	ribosomal rna small subunit methyltransferase
Asera_RS26115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Asera_RS26150	COG0589	response to stress
Asera_RS26165	COG0626	cystathionine gamma-synthase activity
Asera_RS26170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Asera_RS26185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Asera_RS26190	COG0406	alpha-ribazole phosphatase activity
Asera_RS26190	COG0494	nUDIX hydrolase
Asera_RS26200	COG0066	3-isopropylmalate dehydratase activity
Asera_RS26205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Asera_RS26235	COG2226	methyltransferase
Asera_RS26240	COG0546	phosphoglycolate phosphatase activity
Asera_RS26245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Asera_RS26250	COG0179	Fumarylacetoacetate (FAA) hydrolase
Asera_RS26260	COG2197	response regulator
Asera_RS26265	COG4585	Histidine kinase
Asera_RS26280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Asera_RS26285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Asera_RS26295	COG0473	3-isopropylmalate dehydrogenase activity
Asera_RS26305	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Asera_RS26310	COG0440	acetolactate synthase activity
Asera_RS26315	COG0028	Belongs to the TPP enzyme family
Asera_RS26320	COG0129	dihydroxy-acid dehydratase activity
Asera_RS26355	COG0318	PFAM AMP-dependent synthetase and ligase
Asera_RS26360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Asera_RS26385	COG2133	pyrroloquinoline quinone binding
Asera_RS26400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Asera_RS26405	COG0154	amidase activity
Asera_RS26410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Asera_RS26420	COG0596	Alpha beta hydrolase
Asera_RS26430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Asera_RS26460	COG0667	Aldo Keto reductase
Asera_RS26470	COG0583	DNA-binding transcription factor activity
Asera_RS26475	COG0482	sulfurtransferase activity
Asera_RS26505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Asera_RS26535	COG3979	chitinase
Asera_RS26545	COG0110	maltose O-acetyltransferase activity
Asera_RS26565	COG1119	ATPase activity
Asera_RS26580	COG1609	Transcriptional regulator
Asera_RS26585	COG1725	Transcriptional regulator
Asera_RS26595	COG1846	Transcriptional regulator
Asera_RS26595	COG1940	carbohydrate kinase activity
Asera_RS26600	COG2182	Extracellular solute-binding protein
Asera_RS26605	COG1175	transmembrane transport
Asera_RS26610	COG0395	ABC-type sugar transport system, permease component
Asera_RS26625	COG0366	Alpha amylase catalytic
Asera_RS26630	COG0366	Alpha amylase catalytic
Asera_RS26650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Asera_RS26660	COG0515	serine threonine protein kinase
Asera_RS26665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Asera_RS26680	COG1309	transcriptional regulator
Asera_RS26690	COG0789	Transcriptional regulator
Asera_RS26695	COG0431	NADPH-dependent FMN reductase
Asera_RS26715	COG4988	ABC transporter
Asera_RS26725	COG1271	oxidase subunit
Asera_RS26740	COG2902	Dehydrogenase
Asera_RS26745	COG0010	Belongs to the arginase family
Asera_RS26755	COG2188	Transcriptional regulator
Asera_RS26770	COG4260	virion core protein, lumpy skin disease virus
Asera_RS26790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_RS26795	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_RS26795	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Asera_RS26800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Asera_RS26825	COG1136	(ABC) transporter
Asera_RS26830	COG1136	(ABC) transporter
Asera_RS26850	COG0183	Belongs to the thiolase family
Asera_RS26855	COG0346	lactoylglutathione lyase activity
Asera_RS26870	COG2860	membrane
Asera_RS26895	COG0667	Aldo Keto reductase
Asera_RS26905	COG0789	Transcriptional regulator
Asera_RS26910	COG3118	belongs to the thioredoxin family
Asera_RS26925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Asera_RS26930	COG2183	response to ionizing radiation
Asera_RS26950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Asera_RS26965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Asera_RS26975	COG2226	methyltransferase
Asera_RS26980	COG1515	deoxyribonuclease V activity
Asera_RS26985	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_RS26990	COG1129	ABC transporter
Asera_RS27000	COG1609	Transcriptional regulator
Asera_RS27005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Asera_RS27015	COG0277	FAD linked oxidase domain protein
Asera_RS27040	COG3386	PFAM SMP-30 Gluconolaconase
Asera_RS27095	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Asera_RS27100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Asera_RS27105	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS27115	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS27120	COG0179	Fumarylacetoacetate (FAA) hydrolase
Asera_RS27125	COG3618	amidohydrolase
Asera_RS27150	COG1556	Lactate utilization protein
Asera_RS27160	COG1131	(ABC) transporter
Asera_RS27175	COG1595	DNA-templated transcription, initiation
Asera_RS27200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Asera_RS27205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Asera_RS27215	COG2226	methyltransferase
Asera_RS27225	COG1414	Transcriptional regulator
Asera_RS27240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_RS27245	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_RS27270	COG2197	response regulator
Asera_RS27275	COG4585	Histidine kinase
Asera_RS27290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Asera_RS27290	COG1213	nucleotidyl transferase
Asera_RS27305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Asera_RS27310	COG1278	Cold shock
Asera_RS27345	COG0515	serine threonine protein kinase
Asera_RS27370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Asera_RS27400	COG3360	Dodecin
Asera_RS27405	COG0583	DNA-binding transcription factor activity
Asera_RS27425	COG4257	antibiotic catabolic process
Asera_RS27465	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Asera_RS27470	COG3387	PFAM Glycoside hydrolase 15-related
Asera_RS27475	COG5285	phytanoyl-CoA dioxygenase
Asera_RS27485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Asera_RS27490	COG0456	acetyltransferase
Asera_RS27495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Asera_RS27495	COG1648	precorrin-2 dehydrogenase activity
Asera_RS27515	COG1797	cobyrinic acid a,c-diamide synthase activity
Asera_RS27525	COG1793	dna ligase
Asera_RS27535	COG1994	Peptidase M50
Asera_RS27540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Asera_RS27545	COG0501	Belongs to the peptidase M48B family
Asera_RS27550	COG1492	cobalamin metabolic process
Asera_RS27555	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Asera_RS27560	COG0629	single-stranded DNA binding
Asera_RS27565	COG1609	Transcriptional regulator
Asera_RS27625	COG2226	methyltransferase
Asera_RS27630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Asera_RS27635	COG0121	glutamine amidotransferase
Asera_RS27640	COG0387	Pfam Sodium calcium exchanger
Asera_RS27655	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Asera_RS27660	COG1595	DNA-templated transcription, initiation
Asera_RS27700	COG1595	DNA-templated transcription, initiation
Asera_RS27735	COG0789	Transcriptional regulator
Asera_RS27745	COG1175	transmembrane transport
Asera_RS27750	COG0395	ABC-type sugar transport system, permease component
Asera_RS27770	COG2409	Drug exporters of the RND superfamily
Asera_RS27780	COG0156	8-amino-7-oxononanoate synthase activity
Asera_RS27800	COG1063	alcohol dehydrogenase
Asera_RS27830	COG0477	Major facilitator Superfamily
Asera_RS27840	COG1175	transmembrane transport
Asera_RS27845	COG1653	transport
Asera_RS27850	COG1472	Belongs to the glycosyl hydrolase 3 family
Asera_RS27855	COG1609	Transcriptional regulator
Asera_RS27890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Asera_RS27910	COG0714	Associated with various cellular activities
Asera_RS27925	COG1609	Transcriptional regulator
Asera_RS27930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Asera_RS27945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Asera_RS27955	COG4266	Belongs to the allantoicase family
Asera_RS27960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Asera_RS28015	COG0701	Predicted permease
Asera_RS28040	COG0667	Aldo Keto reductase
Asera_RS28055	COG3340	Belongs to the peptidase S51 family
Asera_RS28100	COG1136	(ABC) transporter
Asera_RS28100	COG0577	efflux transmembrane transporter activity
Asera_RS28120	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS28135	COG3903	Transcriptional regulator
Asera_RS28135	COG3629	intracellular signal transduction
Asera_RS28145	COG2814	Major facilitator Superfamily
Asera_RS28155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_RS28170	COG4566	intracellular signal transduction
Asera_RS28175	COG0438	transferase activity, transferring glycosyl groups
Asera_RS28195	COG1215	transferase activity, transferring glycosyl groups
Asera_RS28200	COG3858	chitin binding
Asera_RS28200	COG1388	LysM domain
Asera_RS28210	COG0438	transferase activity, transferring glycosyl groups
Asera_RS28220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Asera_RS28250	COG2409	Drug exporters of the RND superfamily
Asera_RS28260	COG1309	transcriptional regulator
Asera_RS28270	COG2197	response regulator
Asera_RS28295	COG3795	YCII-related domain
Asera_RS28300	COG4941	Belongs to the sigma-70 factor family
Asera_RS28335	COG2986	histidine ammonia-lyase
Asera_RS28355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Asera_RS28375	COG2197	response regulator
Asera_RS28405	COG0215	cysteine-tRNA ligase activity
Asera_RS28460	COG2197	response regulator
Asera_RS28475	COG1309	transcriptional regulator
Asera_RS28485	COG1134	teichoic acid transport
Asera_RS28505	COG3119	arylsulfatase activity
Asera_RS28530	COG3119	arylsulfatase activity
Asera_RS28535	COG3119	arylsulfatase activity
Asera_RS28540	COG0395	ABC-type sugar transport system, permease component
Asera_RS28545	COG1175	transmembrane transport
Asera_RS28550	COG2182	Extracellular solute-binding protein
Asera_RS28560	COG1869	D-ribose catabolic process
Asera_RS28565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Asera_RS28570	COG1609	Transcriptional regulator
Asera_RS28580	COG0778	Nitroreductase
Asera_RS28590	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS28620	COG0640	Transcriptional regulator
Asera_RS28625	COG2226	methyltransferase
Asera_RS28660	COG4552	Acetyltransferase involved in intracellular survival and related
Asera_RS28675	COG1172	Belongs to the binding-protein-dependent transport system permease family
Asera_RS28680	COG1129	ABC transporter
Asera_RS28685	COG1414	Transcriptional regulator
Asera_RS28695	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS28740	COG2132	Multicopper oxidase
Asera_RS28765	COG2151	metal-sulfur cluster biosynthetic enzyme
Asera_RS28775	COG0702	epimerase
Asera_RS28790	COG3321	synthase
Asera_RS28790	COG0604	alcohol dehydrogenase
Asera_RS28795	COG1234	tRNA 3'-trailer cleavage
Asera_RS28820	COG1921	L-seryl-tRNASec selenium transferase activity
Asera_RS28825	COG0709	Synthesizes selenophosphate from selenide and ATP
Asera_RS28900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Asera_RS28905	COG2890	protein-(glutamine-N5) methyltransferase activity
Asera_RS28920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Asera_RS28995	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS29015	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS29020	COG0277	FAD linked oxidase domain protein
Asera_RS29020	COG0247	lactate metabolic process
Asera_RS29040	COG4948	Mandelate Racemase Muconate Lactonizing
Asera_RS29045	COG0028	Belongs to the TPP enzyme family
Asera_RS29055	COG0243	molybdopterin cofactor binding
Asera_RS29055	COG3383	formate dehydrogenase (NAD+) activity
Asera_RS29060	COG0243	molybdopterin cofactor binding
Asera_RS29060	COG3383	formate dehydrogenase (NAD+) activity
Asera_RS29065	COG0437	4 iron, 4 sulfur cluster binding
Asera_RS29110	COG0651	ATP synthesis coupled electron transport
Asera_RS29115	COG1006	Multisubunit Na H antiporter MnhC subunit
Asera_RS29180	COG1131	(ABC) transporter
Asera_RS29185	COG1309	transcriptional regulator
Asera_RS29200	COG1131	(ABC) transporter
Asera_RS29215	COG0656	L-ascorbic acid biosynthetic process
Asera_RS29225	COG1181	Belongs to the D-alanine--D-alanine ligase family
Asera_RS29230	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Asera_RS29235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Asera_RS29245	COG2205	protein histidine kinase activity
Asera_RS29250	COG0745	RESPONSE REGULATOR receiver
Asera_RS29260	COG2094	Belongs to the DNA glycosylase MPG family
Asera_RS29300	COG4941	Belongs to the sigma-70 factor family
Asera_RS29325	COG0513	Belongs to the DEAD box helicase family
Asera_RS29340	COG1131	(ABC) transporter
Asera_RS29345	COG0745	RESPONSE REGULATOR receiver
Asera_RS29350	COG2205	protein histidine kinase activity
Asera_RS29355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Asera_RS29360	COG0747	negative chemotaxis
Asera_RS29365	COG0601	transmembrane transport
Asera_RS29370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Asera_RS29380	COG4608	Belongs to the ABC transporter superfamily
Asera_RS29405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Asera_RS29420	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS29450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Asera_RS29470	COG2326	polyphosphate kinase activity
Asera_RS29495	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Asera_RS29495	COG1672	PFAM Archaeal ATPase
Asera_RS29505	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_RS29505	COG3848	Pyruvate phosphate dikinase
Asera_RS29505	COG0574	Belongs to the PEP-utilizing enzyme family
Asera_RS29505	COG3848	Pyruvate phosphate dikinase
Asera_RS29535	COG2207	Transcriptional regulator
Asera_RS29565	COG2226	methyltransferase
Asera_RS29580	COG1733	regulation of RNA biosynthetic process
Asera_RS29590	COG2816	NAD+ diphosphatase activity
Asera_RS29595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Asera_RS29605	COG1280	lysine exporter protein (LysE YggA)
Asera_RS29615	COG2353	YceI-like domain
Asera_RS29645	COG2068	MobA-Related Protein
Asera_RS29695	COG4989	oxidoreductase activity
Asera_RS29715	COG2070	2-Nitropropane dioxygenase
Asera_RS29735	COG0702	epimerase
Asera_RS29740	COG4221	oxidoreductase activity
Asera_RS29780	COG0038	chloride channel
Asera_RS29900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Asera_RS29930	COG2197	response regulator
Asera_RS30090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Asera_RS30095	COG1381	Involved in DNA repair and RecF pathway recombination
Asera_RS30105	COG0667	Aldo Keto reductase
Asera_RS30130	COG0714	Associated with various cellular activities
Asera_RS30140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Asera_RS30155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Asera_RS30170	COG0537	adenosine 5'-monophosphoramidase activity
Asera_RS30180	COG0484	heat shock protein binding
Asera_RS30185	COG1420	regulation of RNA biosynthetic process
Asera_RS30200	COG1024	Enoyl-CoA hydratase
Asera_RS30215	COG1309	transcriptional regulator
Asera_RS30235	COG0481	GTPase activity
Asera_RS30240	COG0268	Binds directly to 16S ribosomal RNA
Asera_RS30260	COG1555	photosystem II stabilization
Asera_RS30270	COG0406	alpha-ribazole phosphatase activity
Asera_RS30275	COG0799	negative regulation of ribosome biogenesis
Asera_RS30280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Asera_RS30295	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Asera_RS30320	COG0180	Tryptophanyl-tRNA synthetase
Asera_RS30335	COG0745	RESPONSE REGULATOR receiver
Asera_RS30340	COG2205	protein histidine kinase activity
Asera_RS30360	COG3345	alpha-galactosidase
Asera_RS30380	COG0698	ribose 5-phosphate isomerase
Asera_RS30390	COG0640	Transcriptional regulator
Asera_RS30410	COG0673	inositol 2-dehydrogenase activity
Asera_RS30450	COG0667	Aldo Keto reductase
Asera_RS30455	COG1309	transcriptional regulator
Asera_RS30465	COG0285	dihydrofolate synthase activity
Asera_RS30470	COG0525	valine-tRNA ligase activity
Asera_RS30490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Asera_RS30495	COG0740	serine-type endopeptidase activity
Asera_RS30500	COG0740	serine-type endopeptidase activity
Asera_RS30505	COG0544	peptidyl-prolyl cis-trans isomerase activity
Asera_RS30565	COG0514	ATP-dependent DNA helicase (RecQ)
Asera_RS30605	COG2135	peptidase activity
Asera_RS30620	COG2119	membrane
Asera_RS30635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Asera_RS30640	COG0515	serine threonine protein kinase
Asera_RS30645	COG4552	Acetyltransferase involved in intracellular survival and related
Asera_RS30660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Asera_RS30690	COG1280	lysine exporter protein (LysE YggA)
Asera_RS30705	COG0702	epimerase
Asera_RS30710	COG1309	transcriptional regulator
Asera_RS30720	COG0105	UTP biosynthetic process
Asera_RS30735	COG2186	Transcriptional regulator
Asera_RS30760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Asera_RS30775	COG2318	DinB family
Asera_RS30780	COG3336	cytochrome c oxidase
Asera_RS30810	COG2197	response regulator
Asera_RS30855	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Asera_RS30875	COG1674	ftsk spoiiie
Asera_RS30910	COG1404	Belongs to the peptidase S8 family
Asera_RS30915	COG4585	Histidine kinase
Asera_RS30930	COG0860	N-Acetylmuramoyl-L-alanine amidase
Asera_RS30950	COG1584	GPR1 FUN34 yaaH family protein
Asera_RS30955	COG1376	ErfK ybiS ycfS ynhG family protein
Asera_RS30970	COG3458	cephalosporin-C deacetylase activity
Asera_RS31040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_RS31055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Asera_RS31095	COG3300	MHYT domain
Asera_RS31095	COG5001	Diguanylate cyclase
Asera_RS31115	COG0477	Major facilitator Superfamily
Asera_RS31125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Asera_RS31125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Asera_RS31130	COG1309	transcriptional regulator
Asera_RS31155	COG1140	nitrate reductase beta subunit
Asera_RS31170	COG1309	transcriptional regulator
Asera_RS31175	COG2409	Drug exporters of the RND superfamily
Asera_RS31185	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Asera_RS31200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Asera_RS31250	COG0640	Transcriptional regulator
Asera_RS31255	COG1191	sigma factor activity
Asera_RS31260	COG2814	Major facilitator Superfamily
Asera_RS31270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Asera_RS31275	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_RS31280	COG0022	dehydrogenase e1 component
Asera_RS31285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Asera_RS31385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Asera_RS31415	COG0667	Aldo Keto reductase
Asera_RS31440	COG1307	EDD domain protein, DegV family
Asera_RS31445	COG1486	melibiose metabolic process
Asera_RS31460	COG1733	regulation of RNA biosynthetic process
Asera_RS31465	COG0183	Belongs to the thiolase family
Asera_RS31495	COG1028	Short-chain dehydrogenase reductase Sdr
Asera_RS31500	COG1309	transcriptional regulator
Asera_RS31505	COG0477	Major facilitator Superfamily
Asera_RS31545	COG0596	Alpha beta hydrolase
Asera_RS31560	COG0596	Alpha beta hydrolase
Asera_RS31565	COG2197	response regulator
Asera_RS31595	COG0765	amino acid transport
Asera_RS31660	COG0110	maltose O-acetyltransferase activity
Asera_RS31695	COG0667	Aldo Keto reductase
Asera_RS31725	COG1309	transcriptional regulator
Asera_RS31780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Asera_RS31800	COG3328	transposase activity
Asera_RS31805	COG1309	transcriptional regulator
Asera_RS31900	COG3328	transposase activity
Asera_RS31940	COG0640	Transcriptional regulator
Asera_RS32000	COG1678	Uncharacterized ACR, COG1678
Asera_RS32005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Asera_RS32015	COG5002	protein histidine kinase activity
Asera_RS32020	COG0745	RESPONSE REGULATOR receiver
Asera_RS32080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Asera_RS32085	COG2177	Part of the ABC transporter FtsEX involved in
Asera_RS32090	COG2884	Cell division ATP-binding protein ftsE
Asera_RS32095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Asera_RS32105	COG0515	serine threonine protein kinase
Asera_RS32110	COG3483	tryptophan 2,3-dioxygenase activity
Asera_RS32125	COG1012	belongs to the aldehyde dehydrogenase family
Asera_RS32165	COG1799	cell septum assembly
Asera_RS32175	COG0653	protein targeting
Asera_RS32190	COG0435	Glutathione S-transferase
Asera_RS32200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Asera_RS32220	COG5401	PFAM Sporulation and spore germination
Asera_RS32225	COG5000	phosphorelay sensor kinase activity
Asera_RS32225	COG5002	protein histidine kinase activity
Asera_RS32230	COG0745	RESPONSE REGULATOR receiver
Asera_RS32235	COG2807	transmembrane transport
Asera_RS32240	COG2186	Transcriptional regulator
Asera_RS32260	COG0714	Associated with various cellular activities
Asera_RS32335	COG1376	ErfK ybiS ycfS ynhG family protein
Asera_RS32340	COG0604	alcohol dehydrogenase
Asera_RS32355	COG1136	(ABC) transporter
Asera_RS32380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Asera_RS32385	COG1408	metallophosphoesterase
Asera_RS32450	COG0464	growth
Asera_RS32500	COG1674	ftsk spoiiie
Asera_RS32525	COG1404	Belongs to the peptidase S8 family
Asera_RS32540	COG0659	secondary active sulfate transmembrane transporter activity
Asera_RS32605	COG4585	Histidine kinase
Asera_RS32610	COG2197	response regulator
Asera_RS32630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Asera_RS32635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Asera_RS32645	COG0402	S-adenosylhomocysteine deaminase activity
Asera_RS32655	COG1228	amidohydrolase
Asera_RS32665	COG2197	response regulator
Asera_RS32690	COG1017	nitric oxide dioxygenase activity
Asera_RS32690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Asera_RS32700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Asera_RS32710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Asera_RS32720	COG1522	sequence-specific DNA binding
Asera_RS32725	COG1285	pathogenesis
Asera_RS32735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Asera_RS32740	COG0673	inositol 2-dehydrogenase activity
Asera_RS32755	COG0745	RESPONSE REGULATOR receiver
Asera_RS32790	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
Asera_RS32800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Asera_RS32810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Asera_RS32825	COG0508	dehydrogenase complex catalyzes the overall conversion of
Asera_RS32825	COG0567	Dehydrogenase, E1 component
Asera_RS32840	COG0673	inositol 2-dehydrogenase activity
Asera_RS32845	COG0583	DNA-binding transcription factor activity