locus-tag	class	description
LUW74_RS00010	COG0366	Alpha amylase catalytic
LUW74_RS00015	COG0366	Alpha amylase catalytic
LUW74_RS00020	COG0058	SHG alpha-glucan phosphorylase activity
LUW74_RS00030	COG1476	TRANSCRIPTIONal
LUW74_RS00035	COG4585	Histidine kinase
LUW74_RS00040	COG4279	zinc finger
LUW74_RS00045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LUW74_RS00065	COG4221	oxidoreductase activity
LUW74_RS00100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LUW74_RS00145	COG0482	sulfurtransferase activity
LUW74_RS00160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LUW74_RS00175	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LUW74_RS00185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LUW74_RS00190	COG2133	pyrroloquinoline quinone binding
LUW74_RS00195	COG5001	Diguanylate cyclase
LUW74_RS00210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LUW74_RS00235	COG1136	(ABC) transporter
LUW74_RS00235	COG0577	efflux transmembrane transporter activity
LUW74_RS00260	COG0473	3-isopropylmalate dehydrogenase activity
LUW74_RS00265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUW74_RS00270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUW74_RS00305	COG2188	Transcriptional regulator
LUW74_RS00325	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS00355	COG2409	Drug exporters of the RND superfamily
LUW74_RS00375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUW74_RS00385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LUW74_RS00400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUW74_RS00410	COG1007	ATP synthesis coupled electron transport
LUW74_RS00435	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
LUW74_RS00455	COG2149	membrane
LUW74_RS00460	COG0789	Transcriptional regulator
LUW74_RS00470	COG1414	Transcriptional regulator
LUW74_RS00475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LUW74_RS00480	COG0066	3-isopropylmalate dehydratase activity
LUW74_RS00490	COG0776	regulation of translation
LUW74_RS00510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LUW74_RS00515	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUW74_RS00555	COG1309	transcriptional regulator
LUW74_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS00610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS00615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS00675	COG0351	phosphomethylpyrimidine kinase
LUW74_RS00680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LUW74_RS00685	COG1461	Dihydroxyacetone kinase
LUW74_RS00715	COG0742	ribosomal rna small subunit methyltransferase
LUW74_RS00720	COG0768	penicillin binding
LUW74_RS00725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LUW74_RS00735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LUW74_RS00745	COG0571	ribonuclease III activity
LUW74_RS00750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LUW74_RS00755	COG1254	Belongs to the acylphosphatase family
LUW74_RS00765	COG1196	nuclear chromosome segregation
LUW74_RS00780	COG3599	regulation of cell shape
LUW74_RS00800	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LUW74_RS00810	COG0228	four-way junction DNA binding
LUW74_RS00815	COG1837	Belongs to the UPF0109 family
LUW74_RS00820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LUW74_RS00835	COG0335	large ribosomal subunit rRNA binding
LUW74_RS00840	COG0681	Belongs to the peptidase S26 family
LUW74_RS00845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LUW74_RS00865	COG0792	nuclease activity
LUW74_RS00870	COG4974	Belongs to the 'phage' integrase family
LUW74_RS00880	COG0052	Belongs to the universal ribosomal protein uS2 family
LUW74_RS00885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LUW74_RS00890	COG0528	UMP kinase activity
LUW74_RS00895	COG0233	cytoplasmic translational termination
LUW74_RS00900	COG0575	Belongs to the CDS family
LUW74_RS00910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LUW74_RS00925	COG1595	DNA-templated transcription, initiation
LUW74_RS00950	COG0494	nUDIX hydrolase
LUW74_RS00960	COG1522	sequence-specific DNA binding
LUW74_RS00965	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS00970	COG3842	ATPase activity
LUW74_RS00980	COG1176	ABC-type spermidine putrescine transport system, permease component I
LUW74_RS00985	COG1177	transmembrane transport
LUW74_RS01010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS01030	COG0631	protein serine/threonine phosphatase activity
LUW74_RS01035	COG0515	serine threonine protein kinase
LUW74_RS01055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LUW74_RS01065	COG0596	Alpha beta hydrolase
LUW74_RS01075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUW74_RS01100	COG2205	protein histidine kinase activity
LUW74_RS01115	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LUW74_RS01125	COG0596	Alpha beta hydrolase
LUW74_RS01190	COG0477	Major facilitator Superfamily
LUW74_RS01200	COG0745	RESPONSE REGULATOR receiver
LUW74_RS01205	COG2205	protein histidine kinase activity
LUW74_RS01210	COG3979	chitinase
LUW74_RS01220	COG0477	Major facilitator Superfamily
LUW74_RS01240	COG3851	Histidine kinase
LUW74_RS01250	COG1309	transcriptional regulator
LUW74_RS01275	COG1515	deoxyribonuclease V activity
LUW74_RS01285	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LUW74_RS01285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LUW74_RS01345	COG4213	ABC transporter substrate-binding protein
LUW74_RS01355	COG4214	carbohydrate transport
LUW74_RS01360	COG4214	carbohydrate transport
LUW74_RS01370	COG1940	carbohydrate kinase activity
LUW74_RS01415	COG0779	Required for maturation of 30S ribosomal subunits
LUW74_RS01430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LUW74_RS01440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LUW74_RS01445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LUW74_RS01450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LUW74_RS01465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LUW74_RS01470	COG1185	polyribonucleotide nucleotidyltransferase activity
LUW74_RS01475	COG0612	Peptidase, M16
LUW74_RS01480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LUW74_RS01485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LUW74_RS01500	COG1595	DNA-templated transcription, initiation
LUW74_RS01505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LUW74_RS01530	COG0477	Major facilitator Superfamily
LUW74_RS01585	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LUW74_RS01600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LUW74_RS01630	COG1058	Belongs to the CinA family
LUW74_RS01630	COG1546	Belongs to the CinA family
LUW74_RS01635	COG1396	sequence-specific DNA binding
LUW74_RS01640	COG0783	Belongs to the Dps family
LUW74_RS01655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LUW74_RS01670	COG0395	ABC-type sugar transport system, permease component
LUW74_RS01675	COG1175	transmembrane transport
LUW74_RS01705	COG1309	transcriptional regulator
LUW74_RS01720	COG0657	acetylesterase activity
LUW74_RS01730	COG0754	glutathionylspermidine amidase activity
LUW74_RS01745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LUW74_RS01750	COG2137	regulation of response to DNA damage stimulus
LUW74_RS01760	COG0584	glycerophosphoryl diester phosphodiesterase
LUW74_RS01765	COG1073	alpha beta
LUW74_RS01770	COG0765	amino acid transport
LUW74_RS01775	COG0765	amino acid transport
LUW74_RS01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS01785	COG1126	abc transporter atp-binding protein
LUW74_RS01790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LUW74_RS01805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LUW74_RS01810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LUW74_RS01820	COG1309	transcriptional regulator
LUW74_RS01855	COG0247	lactate metabolic process
LUW74_RS01860	COG0277	FAD linked oxidase domain protein
LUW74_RS01865	COG0277	FAD linked oxidase domain protein
LUW74_RS01870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LUW74_RS01880	COG1228	amidohydrolase
LUW74_RS01885	COG1307	EDD domain protein, DegV family
LUW74_RS01910	COG1307	EDD domain protein, DegV family
LUW74_RS01915	COG1307	EDD domain protein, DegV family
LUW74_RS01940	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LUW74_RS01945	COG0268	Binds directly to 16S ribosomal RNA
LUW74_RS01950	COG0481	GTPase activity
LUW74_RS01985	COG1420	regulation of RNA biosynthetic process
LUW74_RS01990	COG0484	heat shock protein binding
LUW74_RS02010	COG0537	adenosine 5'-monophosphoramidase activity
LUW74_RS02020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LUW74_RS02035	COG2409	Drug exporters of the RND superfamily
LUW74_RS02040	COG3629	intracellular signal transduction
LUW74_RS02040	COG3903	Transcriptional regulator
LUW74_RS02045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LUW74_RS02060	COG1834	amidinotransferase
LUW74_RS02065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUW74_RS02080	COG1175	transmembrane transport
LUW74_RS02090	COG0366	Alpha amylase catalytic
LUW74_RS02100	COG0789	Transcriptional regulator
LUW74_RS02125	COG1381	Involved in DNA repair and RecF pathway recombination
LUW74_RS02130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LUW74_RS02135	COG1764	response to oxidative stress
LUW74_RS02150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LUW74_RS02155	COG1121	(ABC) transporter
LUW74_RS02185	COG0423	glycine-tRNA ligase activity
LUW74_RS02200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUW74_RS02200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUW74_RS02210	COG3387	PFAM Glycoside hydrolase 15-related
LUW74_RS02230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LUW74_RS02240	COG2223	nitrite transmembrane transporter activity
LUW74_RS02250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS02255	COG0789	Transcriptional regulator
LUW74_RS02285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUW74_RS02290	COG0358	DNA primase activity
LUW74_RS02295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUW74_RS02300	COG0393	Putative heavy-metal-binding
LUW74_RS02310	COG2837	iron assimilation
LUW74_RS02355	COG1358	cellular component organization or biogenesis
LUW74_RS02365	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LUW74_RS02410	COG2111	Na H antiporter
LUW74_RS02410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUW74_RS02415	COG2111	Na H antiporter
LUW74_RS02415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUW74_RS02420	COG1006	Multisubunit Na H antiporter MnhC subunit
LUW74_RS02425	COG0651	ATP synthesis coupled electron transport
LUW74_RS02430	COG1863	multisubunit Na H antiporter MnhE subunit
LUW74_RS02435	COG2212	antiporter activity
LUW74_RS02440	COG1320	monovalent cation:proton antiporter activity
LUW74_RS02450	COG4585	Histidine kinase
LUW74_RS02470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUW74_RS02475	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUW74_RS02480	COG1120	ATPase activity
LUW74_RS02510	COG0559	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS02535	COG1024	Enoyl-CoA hydratase
LUW74_RS02550	COG0477	Major facilitator Superfamily
LUW74_RS02580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LUW74_RS02600	COG0531	amino acid
LUW74_RS02605	COG0405	Gamma-glutamyltransferase
LUW74_RS02620	COG0477	Major facilitator Superfamily
LUW74_RS02630	COG1937	Protein conserved in bacteria
LUW74_RS02635	COG0406	alpha-ribazole phosphatase activity
LUW74_RS02640	COG0686	Belongs to the AlaDH PNT family
LUW74_RS02650	COG1929	Belongs to the glycerate kinase type-1 family
LUW74_RS02655	COG2252	PERMEase
LUW74_RS02695	COG4585	Histidine kinase
LUW74_RS02700	COG2197	response regulator
LUW74_RS02725	COG0745	RESPONSE REGULATOR receiver
LUW74_RS02735	COG2205	protein histidine kinase activity
LUW74_RS02745	COG1733	regulation of RNA biosynthetic process
LUW74_RS02800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LUW74_RS02805	COG0477	Major facilitator Superfamily
LUW74_RS02810	COG1309	transcriptional regulator
LUW74_RS02820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LUW74_RS02820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUW74_RS02835	COG2124	cytochrome p450
LUW74_RS02840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS02845	COG0765	amino acid transport
LUW74_RS02850	COG1126	abc transporter atp-binding protein
LUW74_RS02855	COG0174	glutamine synthetase
LUW74_RS02860	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LUW74_RS02905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LUW74_RS02915	COG0321	lipoyl(octanoyl) transferase activity
LUW74_RS02920	COG3340	Belongs to the peptidase S51 family
LUW74_RS02925	COG1090	epimerase
LUW74_RS02935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUW74_RS02940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUW74_RS02945	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LUW74_RS02965	COG0667	Aldo Keto reductase
LUW74_RS02995	COG0501	Belongs to the peptidase M48B family
LUW74_RS03005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LUW74_RS03015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUW74_RS03020	COG0425	Belongs to the sulfur carrier protein TusA family
LUW74_RS03030	COG1104	cysteine desulfurase activity
LUW74_RS03035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LUW74_RS03050	COG1376	ErfK ybiS ycfS ynhG family protein
LUW74_RS03055	COG0501	Belongs to the peptidase M48B family
LUW74_RS03070	COG0791	NLP P60 protein
LUW74_RS03070	COG1388	LysM domain
LUW74_RS03070	COG3103	Sh3 type 3 domain protein
LUW74_RS03105	COG3842	ATPase activity
LUW74_RS03110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUW74_RS03115	COG1176	ABC-type spermidine putrescine transport system, permease component I
LUW74_RS03120	COG1177	transmembrane transport
LUW74_RS03125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LUW74_RS03135	COG1845	cytochrome c oxidase, subunit III
LUW74_RS03140	COG2010	Cytochrome c
LUW74_RS03145	COG0723	plastoquinol--plastocyanin reductase activity
LUW74_RS03150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUW74_RS03155	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS03200	COG1022	Amp-dependent synthetase and ligase
LUW74_RS03225	COG1940	carbohydrate kinase activity
LUW74_RS03250	COG2197	response regulator
LUW74_RS03260	COG3220	belongs to the UPF0276 family
LUW74_RS03275	COG0301	tRNA thio-modification
LUW74_RS03285	COG0697	spore germination
LUW74_RS03290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LUW74_RS03295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LUW74_RS03310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUW74_RS03315	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LUW74_RS03320	COG0515	serine threonine protein kinase
LUW74_RS03320	COG2815	serine threonine protein kinase
LUW74_RS03330	COG0697	spore germination
LUW74_RS03335	COG2022	thiamine diphosphate biosynthetic process
LUW74_RS03360	COG0352	thiamine-phosphate diphosphorylase activity
LUW74_RS03370	COG0515	serine threonine protein kinase
LUW74_RS03375	COG1472	Belongs to the glycosyl hydrolase 3 family
LUW74_RS03385	COG0142	geranyltranstransferase activity
LUW74_RS03430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS03435	COG2814	Major facilitator Superfamily
LUW74_RS03445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LUW74_RS03450	COG0540	Belongs to the ATCase OTCase family
LUW74_RS03455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LUW74_RS03460	COG0505	Belongs to the CarA family
LUW74_RS03465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LUW74_RS03470	COG0543	2 iron, 2 sulfur cluster binding
LUW74_RS03480	COG0284	orotidine-5'-phosphate decarboxylase activity
LUW74_RS03490	COG0194	GDP metabolic process
LUW74_RS03495	COG1758	RNA polymerase activity
LUW74_RS03505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LUW74_RS03525	COG0242	peptide deformylase activity
LUW74_RS03530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LUW74_RS03540	COG0671	phosphoesterase, PA-phosphatase related
LUW74_RS03545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LUW74_RS03550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUW74_RS03565	COG3201	nicotinamide mononucleotide transporter
LUW74_RS03570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUW74_RS03570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUW74_RS03575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LUW74_RS03580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LUW74_RS03605	COG3608	succinylglutamate desuccinylase aspartoacylase
LUW74_RS03605	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LUW74_RS03610	COG0746	molybdenum cofactor guanylyltransferase activity
LUW74_RS03640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LUW74_RS03645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LUW74_RS03660	COG2233	PERMEase
LUW74_RS03680	COG0726	polysaccharide deacetylase
LUW74_RS03755	COG0655	NAD(P)H dehydrogenase (quinone) activity
LUW74_RS03775	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS03785	COG1309	transcriptional regulator
LUW74_RS03795	COG1131	(ABC) transporter
LUW74_RS03805	COG4585	Histidine kinase
LUW74_RS03810	COG2197	response regulator
LUW74_RS03820	COG0549	Belongs to the carbamate kinase family
LUW74_RS03845	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LUW74_RS03850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LUW74_RS03855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LUW74_RS03860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LUW74_RS03865	COG1309	transcriptional regulator
LUW74_RS03880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS03895	COG0006	proline dipeptidase activity
LUW74_RS03905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUW74_RS03915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LUW74_RS03935	COG0714	Associated with various cellular activities
LUW74_RS03940	COG2001	Belongs to the MraZ family
LUW74_RS03945	COG0275	rRNA processing
LUW74_RS03955	COG0768	penicillin binding
LUW74_RS03960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LUW74_RS03965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LUW74_RS03975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LUW74_RS03985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LUW74_RS03990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUW74_RS04000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LUW74_RS04005	COG1496	oxidoreductase activity
LUW74_RS04015	COG1799	cell septum assembly
LUW74_RS04025	COG3599	regulation of cell shape
LUW74_RS04050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LUW74_RS04085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LUW74_RS04090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LUW74_RS04095	COG0384	phenazine biosynthesis protein PhzF
LUW74_RS04100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LUW74_RS04105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LUW74_RS04110	COG0131	Imidazoleglycerol-phosphate dehydratase
LUW74_RS04120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LUW74_RS04125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LUW74_RS04130	COG0107	imidazoleglycerol-phosphate synthase activity
LUW74_RS04145	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS04150	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS04185	COG1132	(ABC) transporter
LUW74_RS04200	COG1278	Cold shock
LUW74_RS04210	COG0745	RESPONSE REGULATOR receiver
LUW74_RS04220	COG0134	indole-3-glycerol-phosphate synthase activity
LUW74_RS04225	COG0133	tryptophan synthase activity
LUW74_RS04230	COG0159	tryptophan synthase activity
LUW74_RS04275	COG0070	glutamate synthase
LUW74_RS04275	COG0069	glutamate synthase activity
LUW74_RS04275	COG0067	glutamate synthase
LUW74_RS04310	COG0047	phosphoribosylformylglycinamidine synthase activity
LUW74_RS04365	COG2050	protein possibly involved in aromatic compounds catabolism
LUW74_RS04395	COG0237	dephospho-CoA kinase activity
LUW74_RS04425	COG0483	inositol monophosphate 1-phosphatase activity
LUW74_RS04440	COG4585	Histidine kinase
LUW74_RS04445	COG0556	nucleotide-excision repair
LUW74_RS04475	COG2755	lipolytic protein G-D-S-L family
LUW74_RS04495	COG2813	Specifically methylates the guanine in position
LUW74_RS04535	COG2319	Wd-40 repeat
LUW74_RS04535	COG4249	Peptidase C14 caspase catalytic subunit p20
LUW74_RS04570	COG0667	Aldo Keto reductase
LUW74_RS04580	COG2070	2-Nitropropane dioxygenase
LUW74_RS04605	COG1126	abc transporter atp-binding protein
LUW74_RS04610	COG0765	amino acid transport
LUW74_RS04615	COG0765	amino acid transport
LUW74_RS04625	COG5285	phytanoyl-CoA dioxygenase
LUW74_RS04635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUW74_RS04640	COG0456	acetyltransferase
LUW74_RS04655	COG0504	CTP synthase activity
LUW74_RS04660	COG0494	nUDIX hydrolase
LUW74_RS04685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LUW74_RS04705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LUW74_RS04710	COG1160	GTP binding
LUW74_RS04750	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LUW74_RS04775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LUW74_RS04795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUW74_RS04815	COG0277	FAD linked oxidase domain protein
LUW74_RS04820	COG0542	response to heat
LUW74_RS04830	COG1253	flavin adenine dinucleotide binding
LUW74_RS04840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUW74_RS04925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUW74_RS04930	COG0583	DNA-binding transcription factor activity
LUW74_RS04960	COG1357	PFAM Pentapeptide repeats (8 copies)
LUW74_RS04970	COG2890	protein-(glutamine-N5) methyltransferase activity
LUW74_RS05015	COG0745	RESPONSE REGULATOR receiver
LUW74_RS05030	COG0640	Transcriptional regulator
LUW74_RS05060	COG0586	Pfam SNARE associated Golgi protein
LUW74_RS05070	COG2197	response regulator
LUW74_RS05075	COG1063	alcohol dehydrogenase
LUW74_RS05115	COG2259	Doxx family
LUW74_RS05140	COG0477	Major facilitator Superfamily
LUW74_RS05170	COG2318	DinB family
LUW74_RS05215	COG1846	Transcriptional regulator
LUW74_RS05220	COG0446	pyridine nucleotide-disulphide oxidoreductase
LUW74_RS05225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS05240	COG1595	DNA-templated transcription, initiation
LUW74_RS05265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LUW74_RS05285	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS05300	COG1120	ATPase activity
LUW74_RS05305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUW74_RS05340	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUW74_RS05420	COG0776	regulation of translation
LUW74_RS05470	COG0535	radical SAM domain protein
LUW74_RS05515	COG2205	protein histidine kinase activity
LUW74_RS05545	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS05555	COG1595	DNA-templated transcription, initiation
LUW74_RS05585	COG2205	protein histidine kinase activity
LUW74_RS05590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS05610	COG0183	Belongs to the thiolase family
LUW74_RS05615	COG0583	DNA-binding transcription factor activity
LUW74_RS05630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUW74_RS05655	COG2188	Transcriptional regulator
LUW74_RS05675	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LUW74_RS05680	COG0626	cystathionine gamma-synthase activity
LUW74_RS05690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LUW74_RS05695	COG2318	DinB family
LUW74_RS05720	COG0395	ABC-type sugar transport system, permease component
LUW74_RS05770	COG1879	ABC-type sugar transport system periplasmic component
LUW74_RS05775	COG1129	ABC transporter
LUW74_RS05780	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS05785	COG1063	alcohol dehydrogenase
LUW74_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS05800	COG4948	Mandelate Racemase Muconate Lactonizing
LUW74_RS05805	COG0800	Aldolase
LUW74_RS05865	COG0154	amidase activity
LUW74_RS05895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LUW74_RS05925	COG0583	DNA-binding transcription factor activity
LUW74_RS05930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LUW74_RS05950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS05970	COG0730	response to heat
LUW74_RS05975	COG0583	DNA-binding transcription factor activity
LUW74_RS05990	COG1053	succinate dehydrogenase
LUW74_RS05990	COG3976	FMN-binding domain protein
LUW74_RS05995	COG0129	dihydroxy-acid dehydratase activity
LUW74_RS06000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS06015	COG1414	Transcriptional regulator
LUW74_RS06035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUW74_RS06045	COG1024	Enoyl-CoA hydratase
LUW74_RS06050	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS06090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS06100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS06105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS06125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS06150	COG1132	(ABC) transporter
LUW74_RS06180	COG3424	synthase
LUW74_RS06185	COG1024	Enoyl-CoA hydratase
LUW74_RS06190	COG1024	Enoyl-CoA hydratase
LUW74_RS06205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS06215	COG0475	glutathione-regulated potassium exporter activity
LUW74_RS06220	COG2211	Major facilitator Superfamily
LUW74_RS06230	COG1278	Cold shock
LUW74_RS06245	COG0604	alcohol dehydrogenase
LUW74_RS06250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUW74_RS06255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUW74_RS06270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LUW74_RS06275	COG1802	Transcriptional regulator
LUW74_RS06290	COG0154	amidase activity
LUW74_RS06325	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS06340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUW74_RS06380	COG4585	Histidine kinase
LUW74_RS06415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUW74_RS06420	COG1120	ATPase activity
LUW74_RS06430	COG2226	methyltransferase
LUW74_RS06455	COG1309	transcriptional regulator
LUW74_RS06460	COG1309	transcriptional regulator
LUW74_RS06465	COG1131	(ABC) transporter
LUW74_RS06470	COG3559	Exporter of polyketide antibiotics
LUW74_RS06485	COG1024	Enoyl-CoA hydratase
LUW74_RS06495	COG1024	Enoyl-CoA hydratase
LUW74_RS06500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUW74_RS06510	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS06515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LUW74_RS06520	COG1176	ABC-type spermidine putrescine transport system, permease component I
LUW74_RS06525	COG1177	transmembrane transport
LUW74_RS06530	COG3842	ATPase activity
LUW74_RS06540	COG0596	Alpha beta hydrolase
LUW74_RS06545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LUW74_RS06550	COG0686	Belongs to the AlaDH PNT family
LUW74_RS06560	COG3693	PFAM glycoside hydrolase, family 10
LUW74_RS06570	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LUW74_RS06575	COG2072	flavoprotein involved in K transport
LUW74_RS06585	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS06590	COG1129	ABC transporter
LUW74_RS06595	COG1879	ABC-type sugar transport system periplasmic component
LUW74_RS06615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LUW74_RS06640	COG0617	tRNA 3'-terminal CCA addition
LUW74_RS06640	COG0517	IMP dehydrogenase activity
LUW74_RS06640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LUW74_RS06670	COG0589	response to stress
LUW74_RS06715	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LUW74_RS06735	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS06740	COG2072	flavoprotein involved in K transport
LUW74_RS06755	COG0633	Ferredoxin
LUW74_RS06760	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS06775	COG1414	Transcriptional regulator
LUW74_RS06800	COG0183	Belongs to the thiolase family
LUW74_RS06845	COG3618	amidohydrolase
LUW74_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS06875	COG3250	beta-galactosidase activity
LUW74_RS06890	COG1175	transmembrane transport
LUW74_RS06930	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS06935	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS06970	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS06975	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS07025	COG1595	DNA-templated transcription, initiation
LUW74_RS07055	COG2267	carboxylic ester hydrolase activity
LUW74_RS07060	COG1129	ABC transporter
LUW74_RS07070	COG1879	ABC-type sugar transport system periplasmic component
LUW74_RS07090	COG3384	dioxygenase
LUW74_RS07100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS07125	COG0596	Alpha beta hydrolase
LUW74_RS07170	COG3795	YCII-related domain
LUW74_RS07175	COG4941	Belongs to the sigma-70 factor family
LUW74_RS07210	COG2267	carboxylic ester hydrolase activity
LUW74_RS07235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS07255	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS07265	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS07305	COG1802	Transcriptional regulator
LUW74_RS07310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS07310	COG1116	anion transmembrane transporter activity
LUW74_RS07320	COG1174	glycine betaine transport
LUW74_RS07325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS07345	COG1802	Transcriptional regulator
LUW74_RS07400	COG1802	Transcriptional regulator
LUW74_RS07405	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS07420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS07430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUW74_RS07450	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
LUW74_RS07455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS07460	COG1024	Enoyl-CoA hydratase
LUW74_RS07480	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUW74_RS07490	COG2267	carboxylic ester hydrolase activity
LUW74_RS07510	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS07545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS07545	COG2226	methyltransferase
LUW74_RS07545	COG3433	isochorismatase activity
LUW74_RS07560	COG4166	transmembrane transport
LUW74_RS07570	COG1126	abc transporter atp-binding protein
LUW74_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS07585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUW74_RS07585	COG3321	synthase
LUW74_RS07585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUW74_RS07585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS07590	COG3634	alkyl hydroperoxide reductase activity
LUW74_RS07610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS07615	COG3433	isochorismatase activity
LUW74_RS07615	COG2226	methyltransferase
LUW74_RS07615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS07620	COG4106	trans-aconitate 2-methyltransferase activity
LUW74_RS07630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUW74_RS07635	COG0436	Aminotransferase
LUW74_RS07650	COG0596	Alpha beta hydrolase
LUW74_RS07660	COG0405	Gamma-glutamyltransferase
LUW74_RS07665	COG3619	membrane
LUW74_RS07730	COG2181	nitrate reductase activity
LUW74_RS07730	COG0247	lactate metabolic process
LUW74_RS07735	COG0277	FAD linked oxidase domain protein
LUW74_RS07750	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS07760	COG3631	Ketosteroid isomerase-related protein
LUW74_RS07770	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS07775	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS07780	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS07790	COG1984	allophanate hydrolase subunit 2
LUW74_RS07800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LUW74_RS07805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LUW74_RS07815	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS07835	COG1073	alpha beta
LUW74_RS07840	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS07845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS07850	COG0183	Belongs to the thiolase family
LUW74_RS07855	COG0583	DNA-binding transcription factor activity
LUW74_RS07875	COG2376	Dihydroxyacetone kinase
LUW74_RS07890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUW74_RS07920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUW74_RS07940	COG0243	molybdopterin cofactor binding
LUW74_RS07945	COG1366	Belongs to the anti-sigma-factor antagonist family
LUW74_RS07950	COG1191	sigma factor activity
LUW74_RS07955	COG0248	Ppx GppA phosphatase
LUW74_RS07960	COG0723	plastoquinol--plastocyanin reductase activity
LUW74_RS07960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUW74_RS07985	COG0154	amidase activity
LUW74_RS08005	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUW74_RS08010	COG0022	dehydrogenase e1 component
LUW74_RS08025	COG1063	alcohol dehydrogenase
LUW74_RS08040	COG1414	Transcriptional regulator
LUW74_RS08095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUW74_RS08120	COG1999	signal sequence binding
LUW74_RS08140	COG2197	response regulator
LUW74_RS08150	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUW74_RS08180	COG0604	alcohol dehydrogenase
LUW74_RS08180	COG3321	synthase
LUW74_RS08190	COG3321	synthase
LUW74_RS08190	COG0604	alcohol dehydrogenase
LUW74_RS08200	COG3321	synthase
LUW74_RS08200	COG0604	alcohol dehydrogenase
LUW74_RS08210	COG0604	alcohol dehydrogenase
LUW74_RS08210	COG3321	synthase
LUW74_RS08245	COG3321	synthase
LUW74_RS08245	COG0604	alcohol dehydrogenase
LUW74_RS08265	COG3903	Transcriptional regulator
LUW74_RS08265	COG3629	intracellular signal transduction
LUW74_RS08310	COG0667	Aldo Keto reductase
LUW74_RS08410	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS08420	COG1309	transcriptional regulator
LUW74_RS08425	COG0183	Belongs to the thiolase family
LUW74_RS08435	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LUW74_RS08440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LUW74_RS08445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LUW74_RS08455	COG1414	Transcriptional regulator
LUW74_RS08460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LUW74_RS08480	COG1024	Enoyl-CoA hydratase
LUW74_RS08485	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS08500	COG0667	Aldo Keto reductase
LUW74_RS08530	COG1024	Enoyl-CoA hydratase
LUW74_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS08545	COG0515	serine threonine protein kinase
LUW74_RS08550	COG1643	Atp-dependent helicase
LUW74_RS08585	COG1119	ATPase activity
LUW74_RS08595	COG2409	Drug exporters of the RND superfamily
LUW74_RS08630	COG2084	Dehydrogenase
LUW74_RS08645	COG2050	protein possibly involved in aromatic compounds catabolism
LUW74_RS08670	COG1131	(ABC) transporter
LUW74_RS08675	COG4585	Histidine kinase
LUW74_RS08680	COG2197	response regulator
LUW74_RS08690	COG1309	transcriptional regulator
LUW74_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS08840	COG1129	ABC transporter
LUW74_RS08845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS08895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LUW74_RS08900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUW74_RS08925	COG0494	nUDIX hydrolase
LUW74_RS08940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LUW74_RS08955	COG4999	Histidine kinase
LUW74_RS08955	COG3850	Histidine kinase
LUW74_RS08955	COG3437	response regulator, receiver
LUW74_RS08955	COG2205	protein histidine kinase activity
LUW74_RS08975	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LUW74_RS08985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUW74_RS09020	COG2814	Major facilitator Superfamily
LUW74_RS09045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LUW74_RS09055	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS09060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS09085	COG2124	cytochrome p450
LUW74_RS09120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUW74_RS09125	COG4166	transmembrane transport
LUW74_RS09130	COG0601	transmembrane transport
LUW74_RS09135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUW74_RS09145	COG4608	Belongs to the ABC transporter superfamily
LUW74_RS09155	COG0702	epimerase
LUW74_RS09180	COG2205	protein histidine kinase activity
LUW74_RS09190	COG2172	sigma factor antagonist activity
LUW74_RS09195	COG1366	Belongs to the anti-sigma-factor antagonist family
LUW74_RS09200	COG1366	Belongs to the anti-sigma-factor antagonist family
LUW74_RS09215	COG1136	(ABC) transporter
LUW74_RS09215	COG0577	efflux transmembrane transporter activity
LUW74_RS09250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUW74_RS09270	COG2366	antibiotic biosynthetic process
LUW74_RS09280	COG0488	(ABC) transporter
LUW74_RS09290	COG0583	DNA-binding transcription factor activity
LUW74_RS09315	COG1917	Cupin 2, conserved barrel domain protein
LUW74_RS09325	COG3844	kynureninase activity
LUW74_RS09330	COG1278	Cold shock
LUW74_RS09365	COG2197	response regulator
LUW74_RS09375	COG4585	Histidine kinase
LUW74_RS09390	COG0477	Major facilitator Superfamily
LUW74_RS09395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LUW74_RS09435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LUW74_RS09440	COG1560	Kdo2-lipid A biosynthetic process
LUW74_RS09445	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS09460	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LUW74_RS09470	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LUW74_RS09475	COG0217	transcriptional regulatory protein
LUW74_RS09490	COG0632	four-way junction helicase activity
LUW74_RS09495	COG2255	four-way junction helicase activity
LUW74_RS09510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUW74_RS09515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUW74_RS09520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LUW74_RS09525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUW74_RS09535	COG0124	histidyl-tRNA synthetase
LUW74_RS09540	COG0124	histidyl-tRNA synthetase
LUW74_RS09555	COG1196	nuclear chromosome segregation
LUW74_RS09605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LUW74_RS09610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LUW74_RS09625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUW74_RS09635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LUW74_RS09645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LUW74_RS09650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUW74_RS09660	COG5002	protein histidine kinase activity
LUW74_RS09665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LUW74_RS09685	COG0488	(ABC) transporter
LUW74_RS09710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LUW74_RS09720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LUW74_RS09730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUW74_RS09735	COG1438	arginine binding
LUW74_RS09740	COG0165	Argininosuccinate lyase
LUW74_RS09745	COG2094	Belongs to the DNA glycosylase MPG family
LUW74_RS09755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LUW74_RS09810	COG1309	transcriptional regulator
LUW74_RS09870	COG1522	sequence-specific DNA binding
LUW74_RS09890	COG0477	Major facilitator Superfamily
LUW74_RS09905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LUW74_RS09920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LUW74_RS09925	COG0583	DNA-binding transcription factor activity
LUW74_RS09935	COG1376	ErfK ybiS ycfS ynhG family protein
LUW74_RS09940	COG1376	ErfK ybiS ycfS ynhG family protein
LUW74_RS09945	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS09950	COG2205	protein histidine kinase activity
LUW74_RS09955	COG2205	protein histidine kinase activity
LUW74_RS09960	COG0745	RESPONSE REGULATOR receiver
LUW74_RS09975	COG1136	(ABC) transporter
LUW74_RS09980	COG0577	efflux transmembrane transporter activity
LUW74_RS09990	COG1070	Carbohydrate kinase
LUW74_RS10030	COG0395	ABC-type sugar transport system, permease component
LUW74_RS10045	COG2851	Citrate transporter
LUW74_RS10060	COG5297	Belongs to the glycosyl hydrolase family 6
LUW74_RS10075	COG4733	cellulase activity
LUW74_RS10075	COG5297	Belongs to the glycosyl hydrolase family 6
LUW74_RS10090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LUW74_RS10165	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS10185	COG3559	Exporter of polyketide antibiotics
LUW74_RS10190	COG1131	(ABC) transporter
LUW74_RS10195	COG1309	transcriptional regulator
LUW74_RS10200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUW74_RS10205	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUW74_RS10220	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LUW74_RS10225	COG1021	2,3-dihydroxybenzoate-AMP ligase
LUW74_RS10315	COG1169	isochorismate synthase
LUW74_RS10325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS10325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS10335	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LUW74_RS10365	COG1309	transcriptional regulator
LUW74_RS10385	COG0559	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS10395	COG1349	DNA-binding transcription factor activity
LUW74_RS10400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUW74_RS10415	COG2213	PTS system mannitol-specific
LUW74_RS10415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUW74_RS10435	COG0697	spore germination
LUW74_RS10485	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LUW74_RS10500	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS10540	COG0673	inositol 2-dehydrogenase activity
LUW74_RS10585	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS10610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS10615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS10625	COG3290	protein histidine kinase activity
LUW74_RS10630	COG4565	transcriptional regulatory protein
LUW74_RS10635	COG1131	(ABC) transporter
LUW74_RS10665	COG1215	transferase activity, transferring glycosyl groups
LUW74_RS10670	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS10680	COG4585	Histidine kinase
LUW74_RS10685	COG2197	response regulator
LUW74_RS10690	COG1309	transcriptional regulator
LUW74_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS10700	COG2272	Belongs to the type-B carboxylesterase lipase family
LUW74_RS10710	COG2197	response regulator
LUW74_RS10730	COG1609	Transcriptional regulator
LUW74_RS10755	COG0395	ABC-type sugar transport system, permease component
LUW74_RS10760	COG0252	asparaginase activity
LUW74_RS10780	COG1902	pentaerythritol trinitrate reductase activity
LUW74_RS10785	COG3665	Urea carboxylase-associated protein
LUW74_RS10790	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS10795	COG1595	DNA-templated transcription, initiation
LUW74_RS10810	COG1472	Belongs to the glycosyl hydrolase 3 family
LUW74_RS10835	COG1309	transcriptional regulator
LUW74_RS10845	COG1309	transcriptional regulator
LUW74_RS10850	COG4608	Belongs to the ABC transporter superfamily
LUW74_RS10855	COG0444	Belongs to the ABC transporter superfamily
LUW74_RS10865	COG0601	transmembrane transport
LUW74_RS10905	COG0346	lactoylglutathione lyase activity
LUW74_RS10925	COG2378	regulation of single-species biofilm formation
LUW74_RS10930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUW74_RS10950	COG0243	molybdopterin cofactor binding
LUW74_RS10965	COG2050	protein possibly involved in aromatic compounds catabolism
LUW74_RS10980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LUW74_RS10985	COG0657	acetylesterase activity
LUW74_RS10995	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS11000	COG0477	Major facilitator Superfamily
LUW74_RS11015	COG1690	Belongs to the RtcB family
LUW74_RS11025	COG1940	carbohydrate kinase activity
LUW74_RS11030	COG1653	transport
LUW74_RS11035	COG1175	transmembrane transport
LUW74_RS11040	COG0395	ABC-type sugar transport system, permease component
LUW74_RS11045	COG2723	6-phospho-beta-galactosidase activity
LUW74_RS11055	COG1137	ATPase activity
LUW74_RS11065	COG3973	AAA domain
LUW74_RS11085	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS11090	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS11095	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LUW74_RS11100	COG0563	adenylate kinase activity
LUW74_RS11110	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LUW74_RS11110	COG3608	succinylglutamate desuccinylase aspartoacylase
LUW74_RS11125	COG3629	intracellular signal transduction
LUW74_RS11125	COG3903	Transcriptional regulator
LUW74_RS11135	COG3485	protocatechuate 3,4-dioxygenase
LUW74_RS11140	COG3485	protocatechuate 3,4-dioxygenase
LUW74_RS11145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LUW74_RS11155	COG1414	Transcriptional regulator
LUW74_RS11170	COG0189	ligase activity
LUW74_RS11170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LUW74_RS11185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LUW74_RS11200	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LUW74_RS11235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LUW74_RS11240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LUW74_RS11260	COG0859	PFAM glycosyl transferase family 9
LUW74_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS11270	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LUW74_RS11270	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LUW74_RS11275	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LUW74_RS11280	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS11305	COG2192	nodulation
LUW74_RS11325	COG0477	Major facilitator Superfamily
LUW74_RS11340	COG0667	Aldo Keto reductase
LUW74_RS11355	COG2030	dehydratase
LUW74_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS11360	COG0583	DNA-binding transcription factor activity
LUW74_RS11380	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS11390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LUW74_RS11410	COG0683	leucine binding
LUW74_RS11415	COG2423	ornithine cyclodeaminase activity
LUW74_RS11445	COG3938	Belongs to the proline racemase family
LUW74_RS11470	COG0166	Belongs to the GPI family
LUW74_RS11485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUW74_RS11500	COG2188	Transcriptional regulator
LUW74_RS11525	COG0702	epimerase
LUW74_RS11545	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LUW74_RS11555	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LUW74_RS11570	COG4585	Histidine kinase
LUW74_RS11580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LUW74_RS11585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUW74_RS11590	COG1280	lysine exporter protein (LysE YggA)
LUW74_RS11600	COG3879	Bacterial protein of unknown function (DUF881)
LUW74_RS11665	COG0247	lactate metabolic process
LUW74_RS11670	COG1139	Iron-sulfur cluster binding protein
LUW74_RS11675	COG1556	Lactate utilization protein
LUW74_RS11700	COG2223	nitrite transmembrane transporter activity
LUW74_RS11715	COG0243	molybdopterin cofactor binding
LUW74_RS11755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUW74_RS11770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LUW74_RS11780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LUW74_RS11790	COG2365	Tyrosine phosphatase family
LUW74_RS11815	COG1169	isochorismate synthase
LUW74_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS11840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUW74_RS11845	COG4977	sequence-specific DNA binding
LUW74_RS11850	COG2249	NAD(P)H dehydrogenase (quinone) activity
LUW74_RS11860	COG1649	PFAM Uncharacterised BCR, COG1649
LUW74_RS11870	COG1733	regulation of RNA biosynthetic process
LUW74_RS11955	COG0085	RNA polymerase activity
LUW74_RS11995	COG1472	Belongs to the glycosyl hydrolase 3 family
LUW74_RS12015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS12020	COG1295	ribonuclease BN
LUW74_RS12035	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS12050	COG0477	Major facilitator Superfamily
LUW74_RS12055	COG4257	antibiotic catabolic process
LUW74_RS12095	COG2205	protein histidine kinase activity
LUW74_RS12100	COG0745	RESPONSE REGULATOR receiver
LUW74_RS12105	COG2409	Drug exporters of the RND superfamily
LUW74_RS12145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUW74_RS12150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUW74_RS12180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUW74_RS12190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LUW74_RS12215	COG0596	Alpha beta hydrolase
LUW74_RS12235	COG0583	DNA-binding transcription factor activity
LUW74_RS12240	COG0477	Major facilitator Superfamily
LUW74_RS12270	COG1278	Cold shock
LUW74_RS12305	COG1162	GTPase activity
LUW74_RS12320	COG0745	RESPONSE REGULATOR receiver
LUW74_RS12325	COG2205	protein histidine kinase activity
LUW74_RS12335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LUW74_RS12340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LUW74_RS12345	COG2154	pterin-4-alpha-carbinolamine dehydratase
LUW74_RS12385	COG3467	pyridoxamine 5'-phosphate
LUW74_RS12390	COG1309	transcriptional regulator
LUW74_RS12405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUW74_RS12425	COG0583	DNA-binding transcription factor activity
LUW74_RS12485	COG0583	DNA-binding transcription factor activity
LUW74_RS12500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUW74_RS12540	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS12555	COG1739	Uncharacterized protein family UPF0029
LUW74_RS12595	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LUW74_RS12605	COG2890	protein-(glutamine-N5) methyltransferase activity
LUW74_RS12640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LUW74_RS12645	COG1595	DNA-templated transcription, initiation
LUW74_RS12650	COG2197	response regulator
LUW74_RS12655	COG4585	Histidine kinase
LUW74_RS12695	COG4974	Belongs to the 'phage' integrase family
LUW74_RS12755	COG1271	oxidase subunit
LUW74_RS12765	COG4988	ABC transporter
LUW74_RS12770	COG1132	(ABC) transporter
LUW74_RS12775	COG1132	(ABC) transporter
LUW74_RS12775	COG2375	cellular response to nickel ion
LUW74_RS12785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUW74_RS12835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS12865	COG2111	Na H antiporter
LUW74_RS12865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUW74_RS12885	COG2378	regulation of single-species biofilm formation
LUW74_RS12935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LUW74_RS12940	COG0657	acetylesterase activity
LUW74_RS12975	COG2304	oxidoreductase activity
LUW74_RS12995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUW74_RS13000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LUW74_RS13030	COG0740	serine-type endopeptidase activity
LUW74_RS13035	COG0740	serine-type endopeptidase activity
LUW74_RS13050	COG4585	Histidine kinase
LUW74_RS13070	COG3030	protein affecting phage T7 exclusion by the F plasmid
LUW74_RS13075	COG1216	Glycosyl transferase, family 2
LUW74_RS13090	COG1607	acyl-coa hydrolase
LUW74_RS13095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LUW74_RS13105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LUW74_RS13135	COG0604	alcohol dehydrogenase
LUW74_RS13140	COG1509	lysine 2,3-aminomutase activity
LUW74_RS13145	COG2124	cytochrome p450
LUW74_RS13155	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS13175	COG1522	sequence-specific DNA binding
LUW74_RS13190	COG0395	ABC-type sugar transport system, permease component
LUW74_RS13195	COG1175	transmembrane transport
LUW74_RS13200	COG1653	transport
LUW74_RS13215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUW74_RS13225	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LUW74_RS13235	COG5398	heme oxygenase
LUW74_RS13255	COG2146	nitrite reductase [NAD(P)H] activity
LUW74_RS13255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LUW74_RS13270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LUW74_RS13290	COG0247	lactate metabolic process
LUW74_RS13290	COG0277	FAD linked oxidase domain protein
LUW74_RS13300	COG0577	efflux transmembrane transporter activity
LUW74_RS13300	COG1136	(ABC) transporter
LUW74_RS13335	COG0805	protein transport
LUW74_RS13340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LUW74_RS13375	COG0544	peptidyl-prolyl cis-trans isomerase activity
LUW74_RS13385	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LUW74_RS13390	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LUW74_RS13440	COG2197	response regulator
LUW74_RS13445	COG1136	(ABC) transporter
LUW74_RS13445	COG0577	efflux transmembrane transporter activity
LUW74_RS13450	COG0577	efflux transmembrane transporter activity
LUW74_RS13455	COG4608	Belongs to the ABC transporter superfamily
LUW74_RS13460	COG0444	Belongs to the ABC transporter superfamily
LUW74_RS13470	COG0747	negative chemotaxis
LUW74_RS13475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUW74_RS13485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUW74_RS13500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LUW74_RS13515	COG0215	cysteine-tRNA ligase activity
LUW74_RS13520	COG0601	transmembrane transport
LUW74_RS13550	COG0598	Magnesium transport protein CorA
LUW74_RS13585	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS13600	COG3360	Dodecin
LUW74_RS13610	COG0515	serine threonine protein kinase
LUW74_RS13640	COG1703	isobutyryl-CoA mutase activity
LUW74_RS13640	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LUW74_RS13640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LUW74_RS13645	COG1846	Transcriptional regulator
LUW74_RS13680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS13685	COG0477	Major facilitator Superfamily
LUW74_RS13700	COG0746	molybdenum cofactor guanylyltransferase activity
LUW74_RS13705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LUW74_RS13710	COG2267	carboxylic ester hydrolase activity
LUW74_RS13715	COG1690	Belongs to the RtcB family
LUW74_RS13725	COG0477	Major facilitator Superfamily
LUW74_RS13740	COG0709	Synthesizes selenophosphate from selenide and ATP
LUW74_RS13760	COG2860	membrane
LUW74_RS13765	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUW74_RS13785	COG0516	GMP reductase activity
LUW74_RS13785	COG0517	IMP dehydrogenase activity
LUW74_RS13790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUW74_RS13795	COG2364	Membrane
LUW74_RS13800	COG1929	Belongs to the glycerate kinase type-1 family
LUW74_RS13810	COG1619	proteins homologs of microcin C7 resistance protein MccF
LUW74_RS13815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LUW74_RS13825	COG1132	(ABC) transporter
LUW74_RS13830	COG2936	dipeptidyl-peptidase activity
LUW74_RS13835	COG1024	Enoyl-CoA hydratase
LUW74_RS13900	COG2151	metal-sulfur cluster biosynthetic enzyme
LUW74_RS13905	COG0822	iron-sulfur transferase activity
LUW74_RS13915	COG0396	ATPase activity
LUW74_RS13940	COG0549	Belongs to the carbamate kinase family
LUW74_RS13945	COG1131	(ABC) transporter
LUW74_RS13965	COG1796	DNA polymerase
LUW74_RS13965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LUW74_RS13985	COG0109	protoheme IX farnesyltransferase activity
LUW74_RS13995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LUW74_RS14010	COG0166	Belongs to the GPI family
LUW74_RS14030	COG0363	glucosamine-6-phosphate deaminase activity
LUW74_RS14035	COG1376	ErfK ybiS ycfS ynhG family protein
LUW74_RS14065	COG0477	Major facilitator Superfamily
LUW74_RS14075	COG4585	Histidine kinase
LUW74_RS14085	COG2197	response regulator
LUW74_RS14090	COG0477	Major facilitator Superfamily
LUW74_RS14110	COG1695	Transcriptional regulator
LUW74_RS14120	COG4585	Histidine kinase
LUW74_RS14125	COG2197	response regulator
LUW74_RS14140	COG2409	Drug exporters of the RND superfamily
LUW74_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS14170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUW74_RS14175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LUW74_RS14205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LUW74_RS14220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUW74_RS14220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS14245	COG1522	sequence-specific DNA binding
LUW74_RS14255	COG2367	Beta-lactamase
LUW74_RS14265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUW74_RS14270	COG0149	triose-phosphate isomerase activity
LUW74_RS14275	COG0126	phosphoglycerate kinase activity
LUW74_RS14280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUW74_RS14300	COG1481	regulation of sporulation
LUW74_RS14305	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LUW74_RS14310	COG1660	Displays ATPase and GTPase activities
LUW74_RS14315	COG0322	excinuclease ABC activity
LUW74_RS14335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUW74_RS14340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUW74_RS14355	COG3903	Transcriptional regulator
LUW74_RS14355	COG3629	intracellular signal transduction
LUW74_RS14380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUW74_RS14400	COG2814	Major facilitator Superfamily
LUW74_RS14410	COG0542	response to heat
LUW74_RS14425	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS14435	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS14465	COG0497	DNA recombination
LUW74_RS14490	COG0647	UMP catabolic process
LUW74_RS14550	COG1024	Enoyl-CoA hydratase
LUW74_RS14580	COG0406	alpha-ribazole phosphatase activity
LUW74_RS14585	COG1070	Carbohydrate kinase
LUW74_RS14595	COG4214	carbohydrate transport
LUW74_RS14605	COG4213	ABC transporter substrate-binding protein
LUW74_RS14610	COG1349	DNA-binding transcription factor activity
LUW74_RS14615	COG0435	Glutathione S-transferase
LUW74_RS14625	COG0431	NADPH-dependent FMN reductase
LUW74_RS14635	COG0673	inositol 2-dehydrogenase activity
LUW74_RS14670	COG3903	Transcriptional regulator
LUW74_RS14670	COG3629	intracellular signal transduction
LUW74_RS14680	COG0247	lactate metabolic process
LUW74_RS14680	COG0277	FAD linked oxidase domain protein
LUW74_RS14735	COG0137	argininosuccinate synthase activity
LUW74_RS14740	COG1742	UPF0060 membrane protein
LUW74_RS14770	COG1136	(ABC) transporter
LUW74_RS14770	COG0577	efflux transmembrane transporter activity
LUW74_RS14790	COG3620	sequence-specific DNA binding
LUW74_RS14830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUW74_RS14845	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS14890	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS14915	COG0702	epimerase
LUW74_RS14925	COG2124	cytochrome p450
LUW74_RS14945	COG0183	Belongs to the thiolase family
LUW74_RS14950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LUW74_RS14990	COG1116	anion transmembrane transporter activity
LUW74_RS14995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS15000	COG0427	acetyl-CoA hydrolase
LUW74_RS15025	COG4689	acetoacetate decarboxylase
LUW74_RS15050	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS15055	COG2078	PFAM AMMECR1 domain protein
LUW74_RS15055	COG3885	ferrous iron binding
LUW74_RS15065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS15070	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS15075	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LUW74_RS15080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LUW74_RS15080	COG0519	Catalyzes the synthesis of GMP from XMP
LUW74_RS15085	COG0583	DNA-binding transcription factor activity
LUW74_RS15130	COG0596	Alpha beta hydrolase
LUW74_RS15145	COG4221	oxidoreductase activity
LUW74_RS15160	COG2226	methyltransferase
LUW74_RS15180	COG0477	Major facilitator Superfamily
LUW74_RS15195	COG3903	Transcriptional regulator
LUW74_RS15195	COG3629	intracellular signal transduction
LUW74_RS15215	COG0745	RESPONSE REGULATOR receiver
LUW74_RS15250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LUW74_RS15255	COG1116	anion transmembrane transporter activity
LUW74_RS15260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS15265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS15280	COG1131	(ABC) transporter
LUW74_RS15300	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS15325	COG1024	Enoyl-CoA hydratase
LUW74_RS15335	COG2124	cytochrome p450
LUW74_RS15350	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS15355	COG2267	carboxylic ester hydrolase activity
LUW74_RS15375	COG2124	cytochrome p450
LUW74_RS15440	COG4733	cellulase activity
LUW74_RS15475	COG3842	ATPase activity
LUW74_RS15515	COG4221	oxidoreductase activity
LUW74_RS15525	COG0477	Major facilitator Superfamily
LUW74_RS15535	COG2301	Belongs to the HpcH HpaI aldolase family
LUW74_RS15545	COG1024	Enoyl-CoA hydratase
LUW74_RS15570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS15585	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS15610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS15615	COG2072	flavoprotein involved in K transport
LUW74_RS15620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS15635	COG4221	oxidoreductase activity
LUW74_RS15640	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15650	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15655	COG0183	Belongs to the thiolase family
LUW74_RS15665	COG1024	Enoyl-CoA hydratase
LUW74_RS15670	COG2186	Transcriptional regulator
LUW74_RS15680	COG0444	Belongs to the ABC transporter superfamily
LUW74_RS15685	COG0601	transmembrane transport
LUW74_RS15740	COG2814	Major facilitator Superfamily
LUW74_RS15745	COG0583	DNA-binding transcription factor activity
LUW74_RS15770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS15780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS15795	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS15805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS15825	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS15860	COG1609	Transcriptional regulator
LUW74_RS15865	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15870	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15875	COG0183	Belongs to the thiolase family
LUW74_RS15895	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15905	COG1024	Enoyl-CoA hydratase
LUW74_RS15915	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15920	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS15925	COG0604	alcohol dehydrogenase
LUW74_RS15925	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS15925	COG3321	synthase
LUW74_RS15935	COG1024	Enoyl-CoA hydratase
LUW74_RS15955	COG1024	Enoyl-CoA hydratase
LUW74_RS15970	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUW74_RS15975	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15980	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15990	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS15995	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS16005	COG1024	Enoyl-CoA hydratase
LUW74_RS16010	COG1024	Enoyl-CoA hydratase
LUW74_RS16015	COG0183	Belongs to the thiolase family
LUW74_RS16020	COG1024	Enoyl-CoA hydratase
LUW74_RS16025	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS16035	COG1063	alcohol dehydrogenase
LUW74_RS16050	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS16120	COG2130	NADP-dependent
LUW74_RS16125	COG0028	Belongs to the TPP enzyme family
LUW74_RS16140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS16145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUW74_RS16150	COG1024	Enoyl-CoA hydratase
LUW74_RS16225	COG3842	ATPase activity
LUW74_RS16230	COG2011	ABC-type metal ion transport system permease component
LUW74_RS16240	COG2182	Extracellular solute-binding protein
LUW74_RS16245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUW74_RS16250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUW74_RS16255	COG0640	Transcriptional regulator
LUW74_RS16275	COG3250	beta-galactosidase activity
LUW74_RS16295	COG0395	ABC-type sugar transport system, permease component
LUW74_RS16320	COG3537	Alpha-1,2-mannosidase
LUW74_RS16340	COG4214	carbohydrate transport
LUW74_RS16345	COG4213	ABC transporter substrate-binding protein
LUW74_RS16350	COG4213	ABC transporter substrate-binding protein
LUW74_RS16355	COG3629	intracellular signal transduction
LUW74_RS16375	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS16380	COG1129	ABC transporter
LUW74_RS16395	COG0434	BtpA family
LUW74_RS16400	COG1609	Transcriptional regulator
LUW74_RS16435	COG2018	Roadblock/LC7 domain
LUW74_RS16475	COG1396	sequence-specific DNA binding
LUW74_RS16480	COG0740	serine-type endopeptidase activity
LUW74_RS16485	COG0740	serine-type endopeptidase activity
LUW74_RS16500	COG0726	polysaccharide deacetylase
LUW74_RS16540	COG1486	melibiose metabolic process
LUW74_RS16555	COG2182	Extracellular solute-binding protein
LUW74_RS16560	COG1175	transmembrane transport
LUW74_RS16565	COG0395	ABC-type sugar transport system, permease component
LUW74_RS16575	COG1105	Belongs to the carbohydrate kinase PfkB family
LUW74_RS16605	COG1595	DNA-templated transcription, initiation
LUW74_RS16625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LUW74_RS16675	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS16685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUW74_RS16690	COG0740	serine-type endopeptidase activity
LUW74_RS16695	COG1414	Transcriptional regulator
LUW74_RS16705	COG2124	cytochrome p450
LUW74_RS16735	COG0437	4 iron, 4 sulfur cluster binding
LUW74_RS16750	COG1946	Acyl-CoA thioesterase
LUW74_RS16760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUW74_RS16775	COG1280	lysine exporter protein (LysE YggA)
LUW74_RS16800	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS16810	COG1176	ABC-type spermidine putrescine transport system, permease component I
LUW74_RS16815	COG3842	ATPase activity
LUW74_RS16825	COG1609	Transcriptional regulator
LUW74_RS16845	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LUW74_RS16860	COG0431	NADPH-dependent FMN reductase
LUW74_RS16880	COG2353	YceI-like domain
LUW74_RS16915	COG2186	Transcriptional regulator
LUW74_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS16940	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS17035	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LUW74_RS17100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LUW74_RS17105	COG1968	undecaprenyl-diphosphatase activity
LUW74_RS17125	COG0402	S-adenosylhomocysteine deaminase activity
LUW74_RS17130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS17155	COG1414	Transcriptional regulator
LUW74_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS17180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LUW74_RS17215	COG1940	carbohydrate kinase activity
LUW74_RS17215	COG1846	Transcriptional regulator
LUW74_RS17225	COG1126	abc transporter atp-binding protein
LUW74_RS17235	COG0765	amino acid transport
LUW74_RS17240	COG0765	amino acid transport
LUW74_RS17250	COG3142	Participates in the control of copper homeostasis
LUW74_RS17260	COG0366	Alpha amylase catalytic
LUW74_RS17280	COG0366	Alpha amylase catalytic
LUW74_RS17285	COG3281	Trehalose synthase
LUW74_RS17295	COG0667	Aldo Keto reductase
LUW74_RS17305	COG3842	ATPase activity
LUW74_RS17315	COG1077	Cell shape determining protein MreB Mrl
LUW74_RS17335	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LUW74_RS17340	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LUW74_RS17365	COG0626	cystathionine gamma-synthase activity
LUW74_RS17390	COG0174	glutamine synthetase
LUW74_RS17415	COG0747	negative chemotaxis
LUW74_RS17440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LUW74_RS17455	COG0235	Class ii aldolase
LUW74_RS17455	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LUW74_RS17470	COG0587	DNA-directed DNA polymerase activity
LUW74_RS17475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUW74_RS17475	COG0515	serine threonine protein kinase
LUW74_RS17480	COG0823	Involved in the tonB-independent uptake of proteins
LUW74_RS17485	COG2409	Drug exporters of the RND superfamily
LUW74_RS17500	COG0248	Ppx GppA phosphatase
LUW74_RS17510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUW74_RS17520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUW74_RS17550	COG0656	L-ascorbic acid biosynthetic process
LUW74_RS17570	COG3250	beta-galactosidase activity
LUW74_RS17575	COG3250	beta-galactosidase activity
LUW74_RS17595	COG3250	beta-galactosidase activity
LUW74_RS17600	COG3250	beta-galactosidase activity
LUW74_RS17605	COG3250	beta-galactosidase activity
LUW74_RS17625	COG3347	Dehydrogenase
LUW74_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS17630	COG3250	beta-galactosidase activity
LUW74_RS17645	COG3254	rhamnose metabolic process
LUW74_RS17650	COG1879	ABC-type sugar transport system periplasmic component
LUW74_RS17665	COG1129	ABC transporter
LUW74_RS17670	COG1609	Transcriptional regulator
LUW74_RS17675	COG0247	lactate metabolic process
LUW74_RS17680	COG1139	Iron-sulfur cluster binding protein
LUW74_RS17685	COG1556	Lactate utilization protein
LUW74_RS17690	COG1070	Carbohydrate kinase
LUW74_RS17695	COG1672	PFAM Archaeal ATPase
LUW74_RS17695	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LUW74_RS17760	COG1643	Atp-dependent helicase
LUW74_RS17790	COG3284	Transcriptional regulator
LUW74_RS17810	COG0183	Belongs to the thiolase family
LUW74_RS17850	COG2755	lipolytic protein G-D-S-L family
LUW74_RS17895	COG3540	Alkaline phosphatase
LUW74_RS17995	COG0210	DNA helicase
LUW74_RS18000	COG2815	serine threonine protein kinase
LUW74_RS18000	COG0515	serine threonine protein kinase
LUW74_RS18010	COG0328	RNA-DNA hybrid ribonuclease activity
LUW74_RS18040	COG0601	transmembrane transport
LUW74_RS18045	COG0444	Belongs to the ABC transporter superfamily
LUW74_RS18070	COG4948	Mandelate Racemase Muconate Lactonizing
LUW74_RS18075	COG2508	Transcriptional regulator
LUW74_RS18075	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LUW74_RS18085	COG0667	Aldo Keto reductase
LUW74_RS18105	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LUW74_RS18110	COG0454	-acetyltransferase
LUW74_RS18120	COG2197	response regulator
LUW74_RS18130	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
LUW74_RS18140	COG0477	Major facilitator Superfamily
LUW74_RS18160	COG1764	response to oxidative stress
LUW74_RS18165	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS18165	COG0204	Acyl-transferase
LUW74_RS18190	COG0668	transmembrane transport
LUW74_RS18215	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS18220	COG1672	PFAM Archaeal ATPase
LUW74_RS18220	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LUW74_RS18285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS18305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS18310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS18320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LUW74_RS18390	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS18430	COG0235	Class ii aldolase
LUW74_RS18435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUW74_RS18440	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS18455	COG0443	Heat shock 70 kDa protein
LUW74_RS18490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS18495	COG1309	transcriptional regulator
LUW74_RS18505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUW74_RS18520	COG1309	transcriptional regulator
LUW74_RS18555	COG2186	Transcriptional regulator
LUW74_RS18560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUW74_RS18575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS18595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUW74_RS18630	COG0714	Associated with various cellular activities
LUW74_RS18655	COG0714	Associated with various cellular activities
LUW74_RS18665	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LUW74_RS18680	COG0640	Transcriptional regulator
LUW74_RS18690	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUW74_RS18705	COG1597	lipid kinase activity
LUW74_RS18715	COG0667	Aldo Keto reductase
LUW74_RS18750	COG0300	oxidoreductase activity
LUW74_RS18765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LUW74_RS18770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LUW74_RS18785	COG4948	Mandelate Racemase Muconate Lactonizing
LUW74_RS18790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LUW74_RS18800	COG1175	transmembrane transport
LUW74_RS18805	COG0395	ABC-type sugar transport system, permease component
LUW74_RS18815	COG0673	inositol 2-dehydrogenase activity
LUW74_RS18825	COG0714	Associated with various cellular activities
LUW74_RS18835	COG2304	oxidoreductase activity
LUW74_RS18840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUW74_RS18845	COG0745	RESPONSE REGULATOR receiver
LUW74_RS18850	COG2205	protein histidine kinase activity
LUW74_RS18870	COG0419	ATPase involved in DNA repair
LUW74_RS18890	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LUW74_RS18960	COG3962	Belongs to the TPP enzyme family
LUW74_RS18965	COG3718	enzyme involved in inositol metabolism
LUW74_RS18975	COG1082	Xylose isomerase domain protein TIM barrel
LUW74_RS18980	COG0673	inositol 2-dehydrogenase activity
LUW74_RS18985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUW74_RS18995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LUW74_RS19000	COG0604	alcohol dehydrogenase
LUW74_RS19005	COG1476	TRANSCRIPTIONal
LUW74_RS19015	COG2814	Major facilitator Superfamily
LUW74_RS19025	COG0477	Major facilitator Superfamily
LUW74_RS19030	COG0456	acetyltransferase
LUW74_RS19030	COG1846	Transcriptional regulator
LUW74_RS19055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LUW74_RS19070	COG0386	Belongs to the glutathione peroxidase family
LUW74_RS19090	COG1316	TRANSCRIPTIONal
LUW74_RS19130	COG2018	Roadblock/LC7 domain
LUW74_RS19140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LUW74_RS19150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS19155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS19175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS19180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS19185	COG1116	anion transmembrane transporter activity
LUW74_RS19185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS19225	COG0277	FAD linked oxidase domain protein
LUW74_RS19275	COG0175	sulfate reduction
LUW74_RS19320	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS19330	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS19355	COG2326	polyphosphate kinase activity
LUW74_RS19415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LUW74_RS19420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUW74_RS19430	COG1131	(ABC) transporter
LUW74_RS19445	COG0446	pyridine nucleotide-disulphide oxidoreductase
LUW74_RS19465	COG0531	amino acid
LUW74_RS19475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUW74_RS19480	COG0549	Belongs to the carbamate kinase family
LUW74_RS19500	COG0516	GMP reductase activity
LUW74_RS19500	COG0517	IMP dehydrogenase activity
LUW74_RS19550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LUW74_RS19605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUW74_RS19615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUW74_RS19620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUW74_RS19625	COG1937	Protein conserved in bacteria
LUW74_RS19660	COG1830	Aldolase
LUW74_RS19670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LUW74_RS19680	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS19690	COG1129	ABC transporter
LUW74_RS19720	COG0145	ligase activity
LUW74_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS19770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUW74_RS19775	COG0531	amino acid
LUW74_RS19790	COG1595	DNA-templated transcription, initiation
LUW74_RS19805	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS19810	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS19815	COG1129	ABC transporter
LUW74_RS19820	COG1879	ABC-type sugar transport system periplasmic component
LUW74_RS19830	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LUW74_RS19835	COG1349	DNA-binding transcription factor activity
LUW74_RS19870	COG1793	dna ligase
LUW74_RS19875	COG3540	Alkaline phosphatase
LUW74_RS19885	COG2186	Transcriptional regulator
LUW74_RS19890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUW74_RS19900	COG2936	dipeptidyl-peptidase activity
LUW74_RS19915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUW74_RS19945	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LUW74_RS19965	COG0672	)-iron permease
LUW74_RS19975	COG0577	efflux transmembrane transporter activity
LUW74_RS19980	COG1136	(ABC) transporter
LUW74_RS19980	COG0577	efflux transmembrane transporter activity
LUW74_RS20000	COG0475	glutathione-regulated potassium exporter activity
LUW74_RS20020	COG3548	integral membrane protein
LUW74_RS20025	COG0745	RESPONSE REGULATOR receiver
LUW74_RS20030	COG2205	protein histidine kinase activity
LUW74_RS20035	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS20045	COG0183	Belongs to the thiolase family
LUW74_RS20050	COG1024	Enoyl-CoA hydratase
LUW74_RS20050	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUW74_RS20055	COG0531	amino acid
LUW74_RS20070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LUW74_RS20075	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LUW74_RS20085	COG1175	transmembrane transport
LUW74_RS20090	COG0395	ABC-type sugar transport system, permease component
LUW74_RS20110	COG1280	lysine exporter protein (LysE YggA)
LUW74_RS20115	COG0667	Aldo Keto reductase
LUW74_RS20130	COG2197	response regulator
LUW74_RS20140	COG2409	Drug exporters of the RND superfamily
LUW74_RS20190	COG1562	ergosterol biosynthetic process
LUW74_RS20200	COG1233	COG1233 Phytoene dehydrogenase and related
LUW74_RS20210	COG1657	PFAM Prenyltransferase squalene oxidase
LUW74_RS20240	COG2197	response regulator
LUW74_RS20260	COG0577	efflux transmembrane transporter activity
LUW74_RS20285	COG0800	Aldolase
LUW74_RS20290	COG0837	glucose binding
LUW74_RS20295	COG0129	dihydroxy-acid dehydratase activity
LUW74_RS20345	COG2084	Dehydrogenase
LUW74_RS20380	COG0297	glycogen (starch) synthase activity
LUW74_RS20400	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUW74_RS20400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUW74_RS20405	COG3541	Predicted nucleotidyltransferase
LUW74_RS20415	COG1653	transport
LUW74_RS20450	COG0395	ABC-type sugar transport system, permease component
LUW74_RS20515	COG2814	Major facilitator Superfamily
LUW74_RS20525	COG1501	Belongs to the glycosyl hydrolase 31 family
LUW74_RS20530	COG0395	ABC-type sugar transport system, permease component
LUW74_RS20535	COG1175	transmembrane transport
LUW74_RS20550	COG4336	lyase activity
LUW74_RS20555	COG1984	allophanate hydrolase subunit 2
LUW74_RS20560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LUW74_RS20565	COG1914	H( )-stimulated, divalent metal cation uptake system
LUW74_RS20575	COG1802	Transcriptional regulator
LUW74_RS20580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LUW74_RS20585	COG0022	dehydrogenase e1 component
LUW74_RS20590	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUW74_RS20610	COG1595	DNA-templated transcription, initiation
LUW74_RS20650	COG1940	carbohydrate kinase activity
LUW74_RS20655	COG0673	inositol 2-dehydrogenase activity
LUW74_RS20660	COG1653	transport
LUW74_RS20695	COG0300	oxidoreductase activity
LUW74_RS20740	COG2188	Transcriptional regulator
LUW74_RS20805	COG1482	cell wall glycoprotein biosynthetic process
LUW74_RS20820	COG1522	sequence-specific DNA binding
LUW74_RS20830	COG3281	Trehalose synthase
LUW74_RS20840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LUW74_RS20845	COG2226	methyltransferase
LUW74_RS20865	COG0477	Major facilitator Superfamily
LUW74_RS20885	COG4552	Acetyltransferase involved in intracellular survival and related
LUW74_RS20910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LUW74_RS20915	COG0531	amino acid
LUW74_RS20920	COG0569	domain protein
LUW74_RS20940	COG0477	Major facilitator Superfamily
LUW74_RS20945	COG0728	peptidoglycan biosynthetic process
LUW74_RS20960	COG1136	(ABC) transporter
LUW74_RS20970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LUW74_RS20980	COG0756	dUTP diphosphatase activity
LUW74_RS21020	COG0706	membrane insertase activity
LUW74_RS21030	COG0525	valine-tRNA ligase activity
LUW74_RS21070	COG0745	RESPONSE REGULATOR receiver
LUW74_RS21115	COG3402	PFAM membrane-flanked domain
LUW74_RS21140	COG1881	PFAM PEBP family protein
LUW74_RS21155	COG0288	reversible hydration of carbon dioxide
LUW74_RS21175	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LUW74_RS21250	COG0251	oxidation-reduction process
LUW74_RS21255	COG0583	DNA-binding transcription factor activity
LUW74_RS21270	COG3321	synthase
LUW74_RS21270	COG0604	alcohol dehydrogenase
LUW74_RS21275	COG0604	alcohol dehydrogenase
LUW74_RS21275	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS21275	COG3321	synthase
LUW74_RS21295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUW74_RS21335	COG1846	Transcriptional regulator
LUW74_RS21375	COG0517	IMP dehydrogenase activity
LUW74_RS21385	COG0464	growth
LUW74_RS21390	COG4451	ribulose bisphosphate carboxylase, small
LUW74_RS21395	COG1850	ribulose-bisphosphate carboxylase activity
LUW74_RS21400	COG0583	DNA-binding transcription factor activity
LUW74_RS21410	COG3268	Saccharopine dehydrogenase
LUW74_RS21420	COG2197	response regulator
LUW74_RS21425	COG0572	uridine kinase
LUW74_RS21450	COG0432	Pfam Uncharacterised protein family UPF0047
LUW74_RS21460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LUW74_RS21525	COG2378	regulation of single-species biofilm formation
LUW74_RS21545	COG2267	carboxylic ester hydrolase activity
LUW74_RS21585	COG0410	ABC transporter
LUW74_RS21610	COG1796	DNA polymerase
LUW74_RS21610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LUW74_RS21620	COG2197	response regulator
LUW74_RS21650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUW74_RS21655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUW74_RS21730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LUW74_RS21740	COG0514	ATP-dependent DNA helicase (RecQ)
LUW74_RS21770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LUW74_RS21800	COG2011	ABC-type metal ion transport system permease component
LUW74_RS21805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LUW74_RS21815	COG1309	transcriptional regulator
LUW74_RS21820	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS21835	COG4585	Histidine kinase
LUW74_RS21840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LUW74_RS21855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LUW74_RS21880	COG2197	response regulator
LUW74_RS21890	COG0187	DNA topoisomerase II activity
LUW74_RS21895	COG1131	(ABC) transporter
LUW74_RS21920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUW74_RS21930	COG4191	Histidine kinase
LUW74_RS21940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LUW74_RS21975	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LUW74_RS21980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LUW74_RS21985	COG1984	allophanate hydrolase subunit 2
LUW74_RS22005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LUW74_RS22085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LUW74_RS22090	COG0495	leucyl-tRNA aminoacylation
LUW74_RS22100	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS22110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LUW74_RS22115	COG0596	Alpha beta hydrolase
LUW74_RS22150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUW74_RS22155	COG0277	FAD linked oxidase domain protein
LUW74_RS22190	COG0577	efflux transmembrane transporter activity
LUW74_RS22195	COG1136	(ABC) transporter
LUW74_RS22235	COG1683	Conserved Protein
LUW74_RS22250	COG1595	DNA-templated transcription, initiation
LUW74_RS22265	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LUW74_RS22375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS22380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS22425	COG0406	alpha-ribazole phosphatase activity
LUW74_RS22435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LUW74_RS22440	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LUW74_RS22445	COG0501	Belongs to the peptidase M48B family
LUW74_RS22455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LUW74_RS22460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LUW74_RS22465	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LUW74_RS22470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LUW74_RS22475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LUW74_RS22480	COG1530	ribonuclease E activity
LUW74_RS22495	COG0772	Belongs to the SEDS family
LUW74_RS22500	COG0768	penicillin binding
LUW74_RS22515	COG1077	Cell shape determining protein MreB Mrl
LUW74_RS22520	COG0105	UTP biosynthetic process
LUW74_RS22550	COG0525	valine-tRNA ligase activity
LUW74_RS22560	COG2197	response regulator
LUW74_RS22565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LUW74_RS22570	COG0740	serine-type endopeptidase activity
LUW74_RS22575	COG0740	serine-type endopeptidase activity
LUW74_RS22580	COG0544	peptidyl-prolyl cis-trans isomerase activity
LUW74_RS22590	COG2183	response to ionizing radiation
LUW74_RS22620	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS22625	COG1309	transcriptional regulator
LUW74_RS22645	COG1733	regulation of RNA biosynthetic process
LUW74_RS22650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUW74_RS22685	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LUW74_RS22730	COG4974	Belongs to the 'phage' integrase family
LUW74_RS22775	COG0596	Alpha beta hydrolase
LUW74_RS22875	COG0789	Transcriptional regulator
LUW74_RS22920	COG3629	intracellular signal transduction
LUW74_RS22920	COG3903	Transcriptional regulator
LUW74_RS22930	COG2409	Drug exporters of the RND superfamily
LUW74_RS22950	COG1140	nitrate reductase beta subunit
LUW74_RS22980	COG1129	ABC transporter
LUW74_RS22985	COG4214	carbohydrate transport
LUW74_RS22990	COG1609	Transcriptional regulator
LUW74_RS23000	COG2160	L-arabinose isomerase activity
LUW74_RS23035	COG0709	Synthesizes selenophosphate from selenide and ATP
LUW74_RS23085	COG2814	Major facilitator Superfamily
LUW74_RS23130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS23135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUW74_RS23145	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS23150	COG0657	acetylesterase activity
LUW74_RS23165	COG4585	Histidine kinase
LUW74_RS23170	COG2197	response regulator
LUW74_RS23190	COG5002	protein histidine kinase activity
LUW74_RS23210	COG0698	ribose 5-phosphate isomerase
LUW74_RS23240	COG0310	cobalt ion transport
LUW74_RS23245	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LUW74_RS23265	COG0154	amidase activity
LUW74_RS23275	COG0129	dihydroxy-acid dehydratase activity
LUW74_RS23300	COG2226	methyltransferase
LUW74_RS23330	COG0668	transmembrane transport
LUW74_RS23340	COG0366	Alpha amylase catalytic
LUW74_RS23350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS23355	COG0824	Thioesterase
LUW74_RS23360	COG4948	Mandelate Racemase Muconate Lactonizing
LUW74_RS23380	COG0629	single-stranded DNA binding
LUW74_RS23395	COG1648	precorrin-2 dehydrogenase activity
LUW74_RS23395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUW74_RS23400	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LUW74_RS23420	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
LUW74_RS23425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS23450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS23465	COG2226	methyltransferase
LUW74_RS23475	COG4585	Histidine kinase
LUW74_RS23480	COG2197	response regulator
LUW74_RS23510	COG1309	transcriptional regulator
LUW74_RS23535	COG0515	serine threonine protein kinase
LUW74_RS23535	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUW74_RS23540	COG1280	lysine exporter protein (LysE YggA)
LUW74_RS23555	COG1492	cobalamin metabolic process
LUW74_RS23560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LUW74_RS23575	COG2160	L-arabinose isomerase activity
LUW74_RS23580	COG1879	ABC-type sugar transport system periplasmic component
LUW74_RS23585	COG1129	ABC transporter
LUW74_RS23595	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS23600	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS23640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LUW74_RS23650	COG1132	(ABC) transporter
LUW74_RS23690	COG1051	belongs to the nudix hydrolase family
LUW74_RS23695	COG1414	Transcriptional regulator
LUW74_RS23705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUW74_RS23710	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS23715	COG1879	ABC-type sugar transport system periplasmic component
LUW74_RS23720	COG1129	ABC transporter
LUW74_RS23725	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS23745	COG0436	Aminotransferase
LUW74_RS23750	COG4977	sequence-specific DNA binding
LUW74_RS23765	COG4977	sequence-specific DNA binding
LUW74_RS23775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LUW74_RS23800	COG0640	Transcriptional regulator
LUW74_RS23815	COG0154	amidase activity
LUW74_RS23825	COG3153	acetyltransferase
LUW74_RS23825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUW74_RS23835	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LUW74_RS23845	COG3940	Belongs to the glycosyl hydrolase 43 family
LUW74_RS23870	COG3119	arylsulfatase activity
LUW74_RS23875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUW74_RS23885	COG1132	(ABC) transporter
LUW74_RS23895	COG2375	cellular response to nickel ion
LUW74_RS23895	COG1132	(ABC) transporter
LUW74_RS23910	COG4585	Histidine kinase
LUW74_RS23915	COG2197	response regulator
LUW74_RS23920	COG2319	Wd-40 repeat
LUW74_RS23920	COG4249	Peptidase C14 caspase catalytic subunit p20
LUW74_RS23960	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS24005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS24020	COG1595	DNA-templated transcription, initiation
LUW74_RS24050	COG3339	Conserved Protein
LUW74_RS24065	COG4977	sequence-specific DNA binding
LUW74_RS24070	COG4447	cellulose binding
LUW74_RS24085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUW74_RS24085	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LUW74_RS24090	COG1349	DNA-binding transcription factor activity
LUW74_RS24100	COG1175	transmembrane transport
LUW74_RS24105	COG0395	ABC-type sugar transport system, permease component
LUW74_RS24150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUW74_RS24155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUW74_RS24160	COG3629	intracellular signal transduction
LUW74_RS24170	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS24200	COG0156	8-amino-7-oxononanoate synthase activity
LUW74_RS24215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUW74_RS24220	COG0156	8-amino-7-oxononanoate synthase activity
LUW74_RS24225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUW74_RS24230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUW74_RS24235	COG2197	response regulator
LUW74_RS24240	COG3469	chitinase activity
LUW74_RS24295	COG2815	serine threonine protein kinase
LUW74_RS24295	COG0515	serine threonine protein kinase
LUW74_RS24340	COG1116	anion transmembrane transporter activity
LUW74_RS24375	COG3903	Transcriptional regulator
LUW74_RS24375	COG3629	intracellular signal transduction
LUW74_RS24425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LUW74_RS24430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LUW74_RS24470	COG1309	transcriptional regulator
LUW74_RS24520	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUW74_RS24560	COG2226	methyltransferase
LUW74_RS24575	COG1047	Peptidyl-prolyl cis-trans
LUW74_RS24580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUW74_RS24655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUW74_RS24665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LUW74_RS24675	COG2197	response regulator
LUW74_RS24730	COG1309	transcriptional regulator
LUW74_RS24745	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS24750	COG1309	transcriptional regulator
LUW74_RS24785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUW74_RS24795	COG3119	arylsulfatase activity
LUW74_RS24815	COG0444	Belongs to the ABC transporter superfamily
LUW74_RS24820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUW74_RS24825	COG0601	transmembrane transport
LUW74_RS24840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LUW74_RS24855	COG1846	Transcriptional regulator
LUW74_RS24860	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LUW74_RS24890	COG4249	Peptidase C14 caspase catalytic subunit p20
LUW74_RS24890	COG2319	Wd-40 repeat
LUW74_RS24895	COG2409	Drug exporters of the RND superfamily
LUW74_RS24905	COG1695	Transcriptional regulator
LUW74_RS24910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LUW74_RS24920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS24935	COG0402	S-adenosylhomocysteine deaminase activity
LUW74_RS25015	COG1366	Belongs to the anti-sigma-factor antagonist family
LUW74_RS25030	COG0702	epimerase
LUW74_RS25045	COG0739	heme binding
LUW74_RS25045	COG0741	lytic transglycosylase activity
LUW74_RS25045	COG1196	nuclear chromosome segregation
LUW74_RS25060	COG0778	Nitroreductase
LUW74_RS25060	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LUW74_RS25080	COG3387	PFAM Glycoside hydrolase 15-related
LUW74_RS25085	COG1063	alcohol dehydrogenase
LUW74_RS25095	COG3629	intracellular signal transduction
LUW74_RS25095	COG3903	Transcriptional regulator
LUW74_RS25120	COG3629	intracellular signal transduction
LUW74_RS25120	COG3903	Transcriptional regulator
LUW74_RS25150	COG0300	oxidoreductase activity
LUW74_RS25165	COG0300	oxidoreductase activity
LUW74_RS25200	COG0477	Major facilitator Superfamily
LUW74_RS25255	COG1414	Transcriptional regulator
LUW74_RS25260	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LUW74_RS25270	COG4608	Belongs to the ABC transporter superfamily
LUW74_RS25310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LUW74_RS25315	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS25330	COG0515	serine threonine protein kinase
LUW74_RS25360	COG3260	NADH ubiquinone oxidoreductase 20
LUW74_RS25370	COG0650	Formate hydrogenlyase subunit 4
LUW74_RS25380	COG0651	ATP synthesis coupled electron transport
LUW74_RS25385	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LUW74_RS25385	COG3261	NADH dehydrogenase
LUW74_RS25395	COG0183	Belongs to the thiolase family
LUW74_RS25405	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS25415	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS25420	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS25435	COG1090	epimerase
LUW74_RS25445	COG1090	epimerase
LUW74_RS25450	COG1595	DNA-templated transcription, initiation
LUW74_RS25455	COG0596	Alpha beta hydrolase
LUW74_RS25485	COG1309	transcriptional regulator
LUW74_RS25500	COG2267	carboxylic ester hydrolase activity
LUW74_RS25530	COG0745	RESPONSE REGULATOR receiver
LUW74_RS25535	COG2205	protein histidine kinase activity
LUW74_RS25545	COG1136	(ABC) transporter
LUW74_RS25575	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS25585	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LUW74_RS25625	COG0726	polysaccharide deacetylase
LUW74_RS25630	COG1024	Enoyl-CoA hydratase
LUW74_RS25640	COG1073	alpha beta
LUW74_RS25640	COG2226	methyltransferase
LUW74_RS25645	COG0215	cysteine-tRNA ligase activity
LUW74_RS25675	COG0006	proline dipeptidase activity
LUW74_RS25690	COG0604	alcohol dehydrogenase
LUW74_RS25690	COG3321	synthase
LUW74_RS25700	COG4585	Histidine kinase
LUW74_RS25750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS25770	COG2255	four-way junction helicase activity
LUW74_RS25780	COG1674	ftsk spoiiie
LUW74_RS25810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUW74_RS25820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LUW74_RS25825	COG1316	TRANSCRIPTIONal
LUW74_RS25845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LUW74_RS25865	COG1132	(ABC) transporter
LUW74_RS25870	COG1132	(ABC) transporter
LUW74_RS25890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LUW74_RS25945	COG1053	succinate dehydrogenase
LUW74_RS25975	COG0515	serine threonine protein kinase
LUW74_RS25980	COG1316	TRANSCRIPTIONal
LUW74_RS26040	COG3883	PFAM NLP P60 protein
LUW74_RS26040	COG0791	NLP P60 protein
LUW74_RS26080	COG2885	chlorophyll binding
LUW74_RS26095	COG4585	Histidine kinase
LUW74_RS26120	COG2894	cell division
LUW74_RS26160	COG0542	response to heat
LUW74_RS26190	COG0791	NLP P60 protein
LUW74_RS26195	COG0494	nUDIX hydrolase
LUW74_RS26205	COG0402	S-adenosylhomocysteine deaminase activity
LUW74_RS26255	COG0012	GTP binding
LUW74_RS26260	COG1322	Protein conserved in bacteria
LUW74_RS26270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LUW74_RS26290	COG1722	exodeoxyribonuclease VII activity
LUW74_RS26315	COG1131	(ABC) transporter
LUW74_RS26350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LUW74_RS26350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LUW74_RS26360	COG0114	fumarate hydratase activity
LUW74_RS26370	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LUW74_RS26375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LUW74_RS26390	COG1331	Highly conserved protein containing a thioredoxin domain
LUW74_RS26400	COG1234	tRNA 3'-trailer cleavage
LUW74_RS26420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LUW74_RS26430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUW74_RS26440	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LUW74_RS26455	COG1714	RDD family
LUW74_RS26460	COG0308	aminopeptidase N
LUW74_RS26475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUW74_RS26505	COG0657	acetylesterase activity
LUW74_RS26505	COG2755	lipolytic protein G-D-S-L family
LUW74_RS26515	COG2409	Drug exporters of the RND superfamily
LUW74_RS26585	COG2205	protein histidine kinase activity
LUW74_RS26600	COG0604	alcohol dehydrogenase
LUW74_RS26600	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS26600	COG3321	synthase
LUW74_RS26605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUW74_RS26630	COG2046	Belongs to the sulfate adenylyltransferase family
LUW74_RS26635	COG0529	Catalyzes the synthesis of activated sulfate
LUW74_RS26635	COG2046	Belongs to the sulfate adenylyltransferase family
LUW74_RS26640	COG0730	response to heat
LUW74_RS26725	COG1218	3'(2'),5'-bisphosphate nucleotidase
LUW74_RS26735	COG0193	aminoacyl-tRNA hydrolase activity
LUW74_RS26740	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LUW74_RS26745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LUW74_RS26750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LUW74_RS26765	COG1309	transcriptional regulator
LUW74_RS26770	COG4106	trans-aconitate 2-methyltransferase activity
LUW74_RS26780	COG0154	amidase activity
LUW74_RS26800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LUW74_RS26805	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LUW74_RS26805	COG4124	Belongs to the glycosyl hydrolase 26 family
LUW74_RS26825	COG0084	hydrolase, TatD family'
LUW74_RS26830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUW74_RS26875	COG1609	Transcriptional regulator
LUW74_RS26880	COG0598	Magnesium transport protein CorA
LUW74_RS26895	COG0583	DNA-binding transcription factor activity
LUW74_RS26910	COG0154	amidase activity
LUW74_RS26955	COG0515	serine threonine protein kinase
LUW74_RS26955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUW74_RS26965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS26990	COG3655	Transcriptional regulator
LUW74_RS27000	COG0477	Major facilitator Superfamily
LUW74_RS27080	COG0457	Tetratricopeptide repeat
LUW74_RS27095	COG2255	four-way junction helicase activity
LUW74_RS27105	COG0604	alcohol dehydrogenase
LUW74_RS27105	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS27105	COG3321	synthase
LUW74_RS27115	COG0640	Transcriptional regulator
LUW74_RS27125	COG1132	(ABC) transporter
LUW74_RS27180	COG1280	lysine exporter protein (LysE YggA)
LUW74_RS27185	COG1309	transcriptional regulator
LUW74_RS27200	COG2197	response regulator
LUW74_RS27210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LUW74_RS27225	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS27240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LUW74_RS27270	COG2124	cytochrome p450
LUW74_RS27275	COG3851	Histidine kinase
LUW74_RS27280	COG2197	response regulator
LUW74_RS27290	COG0515	serine threonine protein kinase
LUW74_RS27295	COG2815	serine threonine protein kinase
LUW74_RS27295	COG0515	serine threonine protein kinase
LUW74_RS27300	COG0515	serine threonine protein kinase
LUW74_RS27305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LUW74_RS27305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LUW74_RS27385	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS27420	COG1846	Transcriptional regulator
LUW74_RS27430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUW74_RS27450	COG1024	Enoyl-CoA hydratase
LUW74_RS27460	COG2070	2-Nitropropane dioxygenase
LUW74_RS27490	COG1216	Glycosyl transferase, family 2
LUW74_RS27505	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS27520	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS27595	COG0641	radical SAM
LUW74_RS27620	COG0583	DNA-binding transcription factor activity
LUW74_RS27650	COG1492	cobalamin metabolic process
LUW74_RS27655	COG1473	amidohydrolase
LUW74_RS27670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LUW74_RS27675	COG0793	Belongs to the peptidase S41A family
LUW74_RS27680	COG2177	Part of the ABC transporter FtsEX involved in
LUW74_RS27685	COG2884	Cell division ATP-binding protein ftsE
LUW74_RS27700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LUW74_RS27730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS27740	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS27745	COG1595	DNA-templated transcription, initiation
LUW74_RS27765	COG1131	(ABC) transporter
LUW74_RS27775	COG1011	Hydrolase
LUW74_RS27795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUW74_RS27800	COG1472	Belongs to the glycosyl hydrolase 3 family
LUW74_RS27810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LUW74_RS27815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUW74_RS27825	COG1263	PTS System
LUW74_RS27825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUW74_RS27825	COG2190	(PTS) system
LUW74_RS27830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUW74_RS27835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUW74_RS27845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LUW74_RS27850	COG2188	Transcriptional regulator
LUW74_RS27855	COG1263	PTS System
LUW74_RS27865	COG0653	protein targeting
LUW74_RS27875	COG3214	Protein conserved in bacteria
LUW74_RS27880	COG2197	response regulator
LUW74_RS27885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LUW74_RS27890	COG1040	competence protein
LUW74_RS27900	COG5401	PFAM Sporulation and spore germination
LUW74_RS27905	COG5002	protein histidine kinase activity
LUW74_RS27905	COG5000	phosphorelay sensor kinase activity
LUW74_RS27910	COG0745	RESPONSE REGULATOR receiver
LUW74_RS27930	COG0714	Associated with various cellular activities
LUW74_RS27960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LUW74_RS27965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LUW74_RS27985	COG2197	response regulator
LUW74_RS27990	COG4585	Histidine kinase
LUW74_RS28005	COG2835	tetraacyldisaccharide 4'-kinase activity
LUW74_RS28010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUW74_RS28055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LUW74_RS28060	COG0778	Nitroreductase
LUW74_RS28060	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LUW74_RS28065	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LUW74_RS28075	COG0583	DNA-binding transcription factor activity
LUW74_RS28105	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS28110	COG1073	alpha beta
LUW74_RS28110	COG2226	methyltransferase
LUW74_RS28120	COG3118	belongs to the thioredoxin family
LUW74_RS28150	COG3594	Acyltransferase
LUW74_RS28155	COG3594	Acyltransferase
LUW74_RS28160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LUW74_RS28165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LUW74_RS28175	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS28215	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS28235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUW74_RS28255	COG3973	AAA domain
LUW74_RS28290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LUW74_RS28310	COG1316	TRANSCRIPTIONal
LUW74_RS28330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LUW74_RS28335	COG1832	CoA-binding protein
LUW74_RS28350	COG3850	Histidine kinase
LUW74_RS28370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LUW74_RS28385	COG2205	protein histidine kinase activity
LUW74_RS28390	COG0745	RESPONSE REGULATOR receiver
LUW74_RS28435	COG1024	Enoyl-CoA hydratase
LUW74_RS28445	COG4941	Belongs to the sigma-70 factor family
LUW74_RS28455	COG3795	YCII-related domain
LUW74_RS28470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LUW74_RS28480	COG1432	Conserved Protein
LUW74_RS28555	COG1674	ftsk spoiiie
LUW74_RS28570	COG4770	biotin carboxylase activity
LUW74_RS28595	COG2197	response regulator
LUW74_RS28625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUW74_RS28635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUW74_RS28675	COG0640	Transcriptional regulator
LUW74_RS28680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LUW74_RS28695	COG2315	Protein conserved in bacteria
LUW74_RS28730	COG0583	DNA-binding transcription factor activity
LUW74_RS28755	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS28765	COG2936	dipeptidyl-peptidase activity
LUW74_RS28780	COG1079	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS28790	COG3845	ABC transporter
LUW74_RS28795	COG1744	ABC transporter substrate-binding protein PnrA-like
LUW74_RS28800	COG1473	amidohydrolase
LUW74_RS28800	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LUW74_RS28805	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LUW74_RS28810	COG1686	Belongs to the peptidase S11 family
LUW74_RS28820	COG1295	ribonuclease BN
LUW74_RS28835	COG4535	Mg2 and Co2 transporter CorC
LUW74_RS28845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LUW74_RS28860	COG0326	Molecular chaperone. Has ATPase activity
LUW74_RS28870	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LUW74_RS28870	COG1672	PFAM Archaeal ATPase
LUW74_RS28930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LUW74_RS28945	COG0138	bifunctional purine biosynthesis protein purh
LUW74_RS28970	COG0045	succinate-CoA ligase (ADP-forming) activity
LUW74_RS28980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS28995	COG2223	nitrite transmembrane transporter activity
LUW74_RS29000	COG2207	Transcriptional regulator
LUW74_RS29020	COG4044	May play a role in the intracellular transport of hydrophobic ligands
LUW74_RS29040	COG1490	D-aminoacyl-tRNA deacylase activity
LUW74_RS29045	COG3246	L-lysine catabolic process to acetate
LUW74_RS29060	COG2807	transmembrane transport
LUW74_RS29065	COG2186	Transcriptional regulator
LUW74_RS29105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUW74_RS29110	COG1309	transcriptional regulator
LUW74_RS29115	COG2409	Drug exporters of the RND superfamily
LUW74_RS29170	COG1595	DNA-templated transcription, initiation
LUW74_RS29190	COG2084	Dehydrogenase
LUW74_RS29225	COG3442	glutamine amidotransferase
LUW74_RS29230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUW74_RS29260	COG0640	Transcriptional regulator
LUW74_RS29340	COG3119	arylsulfatase activity
LUW74_RS29365	COG1316	TRANSCRIPTIONal
LUW74_RS29480	COG1404	Belongs to the peptidase S8 family
LUW74_RS29500	COG4842	Belongs to the WXG100 family
LUW74_RS29515	COG1674	ftsk spoiiie
LUW74_RS29590	COG0745	RESPONSE REGULATOR receiver
LUW74_RS29615	COG0456	acetyltransferase
LUW74_RS29620	COG0737	Belongs to the 5'-nucleotidase family
LUW74_RS29620	COG4085	toxin activity
LUW74_RS29620	COG1525	nuclease
LUW74_RS29625	COG0306	phosphate transporter
LUW74_RS29640	COG0464	growth
LUW74_RS29665	COG0745	RESPONSE REGULATOR receiver
LUW74_RS29680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUW74_RS29690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LUW74_RS29720	COG1024	Enoyl-CoA hydratase
LUW74_RS29730	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS29765	COG1902	pentaerythritol trinitrate reductase activity
LUW74_RS29770	COG4566	intracellular signal transduction
LUW74_RS29810	COG3118	belongs to the thioredoxin family
LUW74_RS29815	COG0071	Belongs to the small heat shock protein (HSP20) family
LUW74_RS29825	COG2197	response regulator
LUW74_RS29835	COG2814	Major facilitator Superfamily
LUW74_RS29845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LUW74_RS29845	COG1672	PFAM Archaeal ATPase
LUW74_RS29855	COG0443	Heat shock 70 kDa protein
LUW74_RS29860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LUW74_RS29875	COG0542	response to heat
LUW74_RS29880	COG1793	dna ligase
LUW74_RS29880	COG3285	dna ligase
LUW74_RS29895	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUW74_RS29995	COG0667	Aldo Keto reductase
LUW74_RS30005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUW74_RS30010	COG3387	PFAM Glycoside hydrolase 15-related
LUW74_RS30030	COG0431	NADPH-dependent FMN reductase
LUW74_RS30040	COG0028	Belongs to the TPP enzyme family
LUW74_RS30055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LUW74_RS30080	COG1191	sigma factor activity
LUW74_RS30110	COG1234	tRNA 3'-trailer cleavage
LUW74_RS30120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS30125	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS30150	COG0596	Alpha beta hydrolase
LUW74_RS30160	COG2409	Drug exporters of the RND superfamily
LUW74_RS30165	COG2409	Drug exporters of the RND superfamily
LUW74_RS30175	COG0745	RESPONSE REGULATOR receiver
LUW74_RS30210	COG1132	(ABC) transporter
LUW74_RS30215	COG1132	(ABC) transporter
LUW74_RS30220	COG0515	serine threonine protein kinase
LUW74_RS30225	COG0515	serine threonine protein kinase
LUW74_RS30255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LUW74_RS30270	COG1309	transcriptional regulator
LUW74_RS30280	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS30285	COG1024	Enoyl-CoA hydratase
LUW74_RS30300	COG0183	Belongs to the thiolase family
LUW74_RS30330	COG1129	ABC transporter
LUW74_RS30345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LUW74_RS30355	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS30360	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS30380	COG2837	iron assimilation
LUW74_RS30425	COG3629	intracellular signal transduction
LUW74_RS30425	COG3903	Transcriptional regulator
LUW74_RS30450	COG4221	oxidoreductase activity
LUW74_RS30470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS30475	COG1116	anion transmembrane transporter activity
LUW74_RS30475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS30485	COG0431	NADPH-dependent FMN reductase
LUW74_RS30525	COG3387	PFAM Glycoside hydrolase 15-related
LUW74_RS30540	COG0477	Major facilitator Superfamily
LUW74_RS30575	COG2226	methyltransferase
LUW74_RS30655	COG2018	Roadblock/LC7 domain
LUW74_RS30700	COG1129	ABC transporter
LUW74_RS30705	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS30725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LUW74_RS30745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUW74_RS30750	COG3386	PFAM SMP-30 Gluconolaconase
LUW74_RS30760	COG1609	Transcriptional regulator
LUW74_RS30770	COG0596	Alpha beta hydrolase
LUW74_RS30840	COG1959	2 iron, 2 sulfur cluster binding
LUW74_RS30855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LUW74_RS30860	COG1115	amino acid carrier protein
LUW74_RS30870	COG1793	dna ligase
LUW74_RS30905	COG2353	YceI-like domain
LUW74_RS30960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LUW74_RS31045	COG1021	2,3-dihydroxybenzoate-AMP ligase
LUW74_RS31060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUW74_RS31135	COG1309	transcriptional regulator
LUW74_RS31140	COG0604	alcohol dehydrogenase
LUW74_RS31150	COG5398	heme oxygenase
LUW74_RS31180	COG4558	Periplasmic binding protein
LUW74_RS31185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUW74_RS31190	COG1120	ATPase activity
LUW74_RS31205	COG2186	Transcriptional regulator
LUW74_RS31210	COG2807	transmembrane transport
LUW74_RS31220	COG2814	Major facilitator Superfamily
LUW74_RS31255	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS31290	COG0596	Alpha beta hydrolase
LUW74_RS31300	COG0066	3-isopropylmalate dehydratase activity
LUW74_RS31305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LUW74_RS31310	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LUW74_RS31325	COG1414	Transcriptional regulator
LUW74_RS31350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS31355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS31360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS31360	COG1116	anion transmembrane transporter activity
LUW74_RS31385	COG1454	alcohol dehydrogenase
LUW74_RS31395	COG0583	DNA-binding transcription factor activity
LUW74_RS31410	COG1309	transcriptional regulator
LUW74_RS31420	COG1414	Transcriptional regulator
LUW74_RS31430	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS31435	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS31440	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS31455	COG3594	Acyltransferase
LUW74_RS31505	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS31515	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LUW74_RS31540	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS31550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUW74_RS31570	COG3279	Response regulator of the LytR AlgR family
LUW74_RS31575	COG3275	phosphorelay sensor kinase activity
LUW74_RS31595	COG1279	arginine transmembrane transporter activity
LUW74_RS31600	COG1917	Cupin 2, conserved barrel domain protein
LUW74_RS31600	COG4977	sequence-specific DNA binding
LUW74_RS31640	COG0596	Alpha beta hydrolase
LUW74_RS31665	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS31675	COG1024	Enoyl-CoA hydratase
LUW74_RS31680	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS31700	COG0737	Belongs to the 5'-nucleotidase family
LUW74_RS31730	COG4977	sequence-specific DNA binding
LUW74_RS31740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUW74_RS31765	COG4935	Belongs to the peptidase S8 family
LUW74_RS31765	COG2234	aminopeptidase activity
LUW74_RS31780	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS31790	COG0477	Major facilitator Superfamily
LUW74_RS31870	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS31950	COG2274	protein secretion by the type I secretion system
LUW74_RS31955	COG3903	Transcriptional regulator
LUW74_RS31955	COG3629	intracellular signal transduction
LUW74_RS31965	COG3903	Transcriptional regulator
LUW74_RS31965	COG3629	intracellular signal transduction
LUW74_RS31975	COG0477	Major facilitator Superfamily
LUW74_RS32015	COG1309	transcriptional regulator
LUW74_RS32025	COG0583	DNA-binding transcription factor activity
LUW74_RS32050	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS32090	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS32120	COG2423	ornithine cyclodeaminase activity
LUW74_RS32130	COG0583	DNA-binding transcription factor activity
LUW74_RS32150	COG0243	molybdopterin cofactor binding
LUW74_RS32165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LUW74_RS32175	COG2186	Transcriptional regulator
LUW74_RS32185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS32190	COG1116	anion transmembrane transporter activity
LUW74_RS32190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS32200	COG2009	succinate dehydrogenase
LUW74_RS32205	COG1053	succinate dehydrogenase
LUW74_RS32210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LUW74_RS32215	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LUW74_RS32220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUW74_RS32225	COG2721	sulfolactate sulfo-lyase activity
LUW74_RS32230	COG2721	sulfolactate sulfo-lyase activity
LUW74_RS32235	COG2197	response regulator
LUW74_RS32250	COG0473	3-isopropylmalate dehydrogenase activity
LUW74_RS32255	COG1802	Transcriptional regulator
LUW74_RS32265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUW74_RS32275	COG5522	Integral membrane protein (intg_mem_TP0381)
LUW74_RS32300	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS32315	COG3568	Endonuclease Exonuclease Phosphatase
LUW74_RS32340	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS32345	COG1309	transcriptional regulator
LUW74_RS32350	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS32360	COG1129	ABC transporter
LUW74_RS32405	COG0464	growth
LUW74_RS32410	COG0583	DNA-binding transcription factor activity
LUW74_RS32415	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS32465	COG0583	DNA-binding transcription factor activity
LUW74_RS32470	COG0584	glycerophosphoryl diester phosphodiesterase
LUW74_RS32480	COG1113	amino acid transport
LUW74_RS32510	COG0791	NLP P60 protein
LUW74_RS32510	COG3883	PFAM NLP P60 protein
LUW74_RS32665	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS32680	COG2207	Transcriptional regulator
LUW74_RS32690	COG1793	dna ligase
LUW74_RS32705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUW74_RS32715	COG3547	Transposase (IS116 IS110 IS902 family)
LUW74_RS32775	COG1518	maintenance of DNA repeat elements
LUW74_RS32780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUW74_RS32820	COG0358	DNA primase activity
LUW74_RS32890	COG0539	negative regulation of cytoplasmic translation
LUW74_RS33025	COG1846	Transcriptional regulator
LUW74_RS33045	COG1942	4-Oxalocrotonate Tautomerase
LUW74_RS33075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS33085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS33090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUW74_RS33090	COG1116	anion transmembrane transporter activity
LUW74_RS33095	COG2186	Transcriptional regulator
LUW74_RS33140	COG0604	alcohol dehydrogenase
LUW74_RS33195	COG0583	DNA-binding transcription factor activity
LUW74_RS33200	COG1760	l-serine dehydratase
LUW74_RS33205	COG3620	sequence-specific DNA binding
LUW74_RS33215	COG0765	amino acid transport
LUW74_RS33220	COG1126	abc transporter atp-binding protein
LUW74_RS33225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS33265	COG1132	(ABC) transporter
LUW74_RS33270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS33300	COG2226	methyltransferase
LUW74_RS33315	COG1082	Xylose isomerase domain protein TIM barrel
LUW74_RS33320	COG2814	Major facilitator Superfamily
LUW74_RS33345	COG1472	Belongs to the glycosyl hydrolase 3 family
LUW74_RS33385	COG0492	ferredoxin-NADP+ reductase activity
LUW74_RS33415	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS33435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LUW74_RS33470	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LUW74_RS33495	COG0464	growth
LUW74_RS33540	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS33580	COG2267	carboxylic ester hydrolase activity
LUW74_RS33595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUW74_RS33675	COG0167	dihydroorotate dehydrogenase activity
LUW74_RS33680	COG2890	protein-(glutamine-N5) methyltransferase activity
LUW74_RS33700	COG1309	transcriptional regulator
LUW74_RS33725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LUW74_RS33780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LUW74_RS33785	COG0047	phosphoribosylformylglycinamidine synthase activity
LUW74_RS33795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LUW74_RS33810	COG0022	dehydrogenase e1 component
LUW74_RS33815	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUW74_RS33830	COG0697	spore germination
LUW74_RS33840	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS33850	COG2076	Multidrug Resistance protein
LUW74_RS33865	COG4221	oxidoreductase activity
LUW74_RS33920	COG0406	alpha-ribazole phosphatase activity
LUW74_RS33920	COG0494	nUDIX hydrolase
LUW74_RS33925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LUW74_RS33945	COG1595	DNA-templated transcription, initiation
LUW74_RS33950	COG2204	response regulator
LUW74_RS33955	COG4251	negative regulation of phosphorylation
LUW74_RS33960	COG0784	Response regulator, receiver
LUW74_RS33990	COG1799	cell septum assembly
LUW74_RS34005	COG0745	RESPONSE REGULATOR receiver
LUW74_RS34015	COG2205	protein histidine kinase activity
LUW74_RS34025	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS34065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUW74_RS34120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LUW74_RS34150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LUW74_RS34195	COG0416	fatty acid biosynthetic process
LUW74_RS34205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LUW74_RS34215	COG1233	COG1233 Phytoene dehydrogenase and related
LUW74_RS34225	COG2770	Histidine kinase
LUW74_RS34225	COG2208	phosphoserine phosphatase activity
LUW74_RS34240	COG0596	Alpha beta hydrolase
LUW74_RS34265	COG2197	response regulator
LUW74_RS34280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LUW74_RS34285	COG0543	2 iron, 2 sulfur cluster binding
LUW74_RS34285	COG0633	Ferredoxin
LUW74_RS34295	COG1064	alcohol dehydrogenase
LUW74_RS34315	COG2706	6-phosphogluconolactonase activity
LUW74_RS34320	COG1733	regulation of RNA biosynthetic process
LUW74_RS34420	COG1136	(ABC) transporter
LUW74_RS34420	COG0577	efflux transmembrane transporter activity
LUW74_RS34445	COG2815	serine threonine protein kinase
LUW74_RS34445	COG0515	serine threonine protein kinase
LUW74_RS34465	COG1247	-acetyltransferase
LUW74_RS34545	COG0714	Associated with various cellular activities
LUW74_RS34645	COG1733	regulation of RNA biosynthetic process
LUW74_RS34660	COG0028	Belongs to the TPP enzyme family
LUW74_RS34700	COG1309	transcriptional regulator
LUW74_RS34705	COG3321	synthase
LUW74_RS34705	COG0604	alcohol dehydrogenase
LUW74_RS34705	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS34750	COG0247	lactate metabolic process
LUW74_RS34750	COG2181	nitrate reductase activity
LUW74_RS34770	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUW74_RS34775	COG0477	Major facilitator Superfamily
LUW74_RS34800	COG1595	DNA-templated transcription, initiation
LUW74_RS34805	COG1404	Belongs to the peptidase S8 family
LUW74_RS34860	COG0443	Heat shock 70 kDa protein
LUW74_RS34865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LUW74_RS34870	COG0484	heat shock protein binding
LUW74_RS34875	COG0789	Transcriptional regulator
LUW74_RS34880	COG0542	response to heat
LUW74_RS34905	COG4941	Belongs to the sigma-70 factor family
LUW74_RS34910	COG3795	YCII-related domain
LUW74_RS34920	COG0596	Alpha beta hydrolase
LUW74_RS34950	COG1432	Conserved Protein
LUW74_RS34965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LUW74_RS34975	COG0586	Pfam SNARE associated Golgi protein
LUW74_RS35020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LUW74_RS35035	COG0151	Belongs to the GarS family
LUW74_RS35040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LUW74_RS35045	COG0633	Ferredoxin
LUW74_RS35045	COG3217	Mosc domain protein beta barrel domain protein
LUW74_RS35055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LUW74_RS35075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LUW74_RS35090	COG2268	Band 7 protein
LUW74_RS35105	COG0204	Acyl-transferase
LUW74_RS35105	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS35115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS35140	COG0515	serine threonine protein kinase
LUW74_RS35150	COG1253	flavin adenine dinucleotide binding
LUW74_RS35170	COG1950	PFAM Membrane protein of
LUW74_RS35180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUW74_RS35185	COG0514	ATP-dependent DNA helicase (RecQ)
LUW74_RS35205	COG0745	RESPONSE REGULATOR receiver
LUW74_RS35220	COG0596	Alpha beta hydrolase
LUW74_RS35225	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS35250	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS35305	COG0022	dehydrogenase e1 component
LUW74_RS35310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LUW74_RS35320	COG0022	dehydrogenase e1 component
LUW74_RS35325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LUW74_RS35330	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUW74_RS35340	COG4948	Mandelate Racemase Muconate Lactonizing
LUW74_RS35355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS35375	COG0431	NADPH-dependent FMN reductase
LUW74_RS35385	COG2271	Major facilitator Superfamily
LUW74_RS35410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS35415	COG3485	protocatechuate 3,4-dioxygenase
LUW74_RS35455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUW74_RS35460	COG0477	Major facilitator Superfamily
LUW74_RS35470	COG0583	DNA-binding transcription factor activity
LUW74_RS35490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS35500	COG0559	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS35535	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS35540	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS35545	COG0183	Belongs to the thiolase family
LUW74_RS35555	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS35590	COG2130	NADP-dependent
LUW74_RS35615	COG1233	COG1233 Phytoene dehydrogenase and related
LUW74_RS35630	COG0789	Transcriptional regulator
LUW74_RS35640	COG0583	DNA-binding transcription factor activity
LUW74_RS35645	COG1024	Enoyl-CoA hydratase
LUW74_RS35650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS35655	COG0477	Major facilitator Superfamily
LUW74_RS35730	COG0477	Major facilitator Superfamily
LUW74_RS35735	COG4249	Peptidase C14 caspase catalytic subunit p20
LUW74_RS35735	COG2319	Wd-40 repeat
LUW74_RS35740	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
LUW74_RS35765	COG2197	response regulator
LUW74_RS35775	COG3629	intracellular signal transduction
LUW74_RS35775	COG3903	Transcriptional regulator
LUW74_RS35850	COG0477	Major facilitator Superfamily
LUW74_RS35860	COG1476	TRANSCRIPTIONal
LUW74_RS35870	COG1846	Transcriptional regulator
LUW74_RS35880	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LUW74_RS35885	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LUW74_RS35905	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS35910	COG1595	DNA-templated transcription, initiation
LUW74_RS35940	COG1846	Transcriptional regulator
LUW74_RS36025	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
LUW74_RS36045	COG0604	alcohol dehydrogenase
LUW74_RS36055	COG0561	phosphatase activity
LUW74_RS36060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LUW74_RS36065	COG2226	methyltransferase
LUW74_RS36070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LUW74_RS36085	COG5650	phosphatidylinositol metabolic process
LUW74_RS36115	COG5002	protein histidine kinase activity
LUW74_RS36120	COG0745	RESPONSE REGULATOR receiver
LUW74_RS36150	COG2235	arginine
LUW74_RS36160	COG5002	protein histidine kinase activity
LUW74_RS36170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUW74_RS36185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LUW74_RS36235	COG1595	DNA-templated transcription, initiation
LUW74_RS36270	COG0140	phosphoribosyl-ATP diphosphatase activity
LUW74_RS36270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LUW74_RS36315	COG0789	Transcriptional regulator
LUW74_RS36350	COG0789	Transcriptional regulator
LUW74_RS36430	COG0477	Major facilitator Superfamily
LUW74_RS36435	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS36465	COG2018	Roadblock/LC7 domain
LUW74_RS36485	COG1136	(ABC) transporter
LUW74_RS36485	COG0577	efflux transmembrane transporter activity
LUW74_RS36490	COG1136	(ABC) transporter
LUW74_RS36505	COG0745	RESPONSE REGULATOR receiver
LUW74_RS36515	COG2205	protein histidine kinase activity
LUW74_RS36525	COG4585	Histidine kinase
LUW74_RS36530	COG2197	response regulator
LUW74_RS36545	COG1716	ATPase activity
LUW74_RS36560	COG0768	penicillin binding
LUW74_RS36565	COG0515	serine threonine protein kinase
LUW74_RS36570	COG0515	serine threonine protein kinase
LUW74_RS36585	COG3764	Sortase (surface protein transpeptidase)
LUW74_RS36600	COG0705	Rhomboid family
LUW74_RS36620	COG0596	Alpha beta hydrolase
LUW74_RS36625	COG0513	Belongs to the DEAD box helicase family
LUW74_RS36630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUW74_RS36650	COG1271	oxidase subunit
LUW74_RS36655	COG1294	oxidase, subunit
LUW74_RS36660	COG4988	ABC transporter
LUW74_RS36690	COG0154	amidase activity
LUW74_RS36695	COG1609	Transcriptional regulator
LUW74_RS36720	COG0667	Aldo Keto reductase
LUW74_RS36730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS36740	COG0402	S-adenosylhomocysteine deaminase activity
LUW74_RS36750	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS36760	COG1247	-acetyltransferase
LUW74_RS36765	COG2226	methyltransferase
LUW74_RS36770	COG0640	Transcriptional regulator
LUW74_RS36780	COG0640	Transcriptional regulator
LUW74_RS36850	COG0346	lactoylglutathione lyase activity
LUW74_RS36860	COG3266	domain, Protein
LUW74_RS36865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LUW74_RS36875	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LUW74_RS36880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LUW74_RS36890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LUW74_RS36895	COG0592	DNA-directed DNA polymerase activity
LUW74_RS36900	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LUW74_RS36905	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LUW74_RS36910	COG0594	ribonuclease P activity
LUW74_RS36915	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LUW74_RS36920	COG0706	membrane insertase activity
LUW74_RS36935	COG0357	Ribosomal RNA small subunit methyltransferase G
LUW74_RS36940	COG1192	Involved in chromosome partitioning
LUW74_RS36955	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUW74_RS36960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUW74_RS36970	COG3118	belongs to the thioredoxin family
LUW74_RS36975	COG0492	ferredoxin-NADP+ reductase activity
LUW74_RS36995	COG1595	DNA-templated transcription, initiation
LUW74_RS37005	COG0515	serine threonine protein kinase
LUW74_RS37005	COG2815	serine threonine protein kinase
LUW74_RS37030	COG0617	tRNA 3'-terminal CCA addition
LUW74_RS37035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LUW74_RS37045	COG4166	transmembrane transport
LUW74_RS37070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUW74_RS37075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUW74_RS37090	COG0789	Transcriptional regulator
LUW74_RS37110	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LUW74_RS37125	COG0360	Binds together with S18 to 16S ribosomal RNA
LUW74_RS37130	COG0629	single-stranded DNA binding
LUW74_RS37135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LUW74_RS37140	COG0359	binds to the 23S rRNA
LUW74_RS37160	COG0305	Participates in initiation and elongation during chromosome replication
LUW74_RS37165	COG1252	NADH dehydrogenase
LUW74_RS37180	COG2318	DinB family
LUW74_RS37190	COG1595	DNA-templated transcription, initiation
LUW74_RS37205	COG1846	Transcriptional regulator
LUW74_RS37225	COG2890	protein-(glutamine-N5) methyltransferase activity
LUW74_RS37260	COG0592	DNA-directed DNA polymerase activity
LUW74_RS37280	COG0537	adenosine 5'-monophosphoramidase activity
LUW74_RS37340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LUW74_RS37365	COG2186	Transcriptional regulator
LUW74_RS37415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LUW74_RS37420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LUW74_RS37440	COG0189	ligase activity
LUW74_RS37445	COG0246	Mannitol dehydrogenase
LUW74_RS37455	COG0745	RESPONSE REGULATOR receiver
LUW74_RS37495	COG1846	Transcriptional regulator
LUW74_RS37530	COG3903	Transcriptional regulator
LUW74_RS37530	COG3629	intracellular signal transduction
LUW74_RS37540	COG0860	N-Acetylmuramoyl-L-alanine amidase
LUW74_RS37580	COG0515	serine threonine protein kinase
LUW74_RS37665	COG1104	cysteine desulfurase activity
LUW74_RS37680	COG0419	ATPase involved in DNA repair
LUW74_RS37750	COG1408	metallophosphoesterase
LUW74_RS37760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUW74_RS37775	COG0667	Aldo Keto reductase
LUW74_RS37780	COG0003	Pfam Anion-transporting ATPase
LUW74_RS37840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUW74_RS37845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUW74_RS37860	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS37875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUW74_RS37885	COG0596	Alpha beta hydrolase
LUW74_RS37895	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LUW74_RS37900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS37975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LUW74_RS37975	COG1672	PFAM Archaeal ATPase
LUW74_RS37980	COG0277	FAD linked oxidase domain protein
LUW74_RS38000	COG1366	Belongs to the anti-sigma-factor antagonist family
LUW74_RS38005	COG2172	sigma factor antagonist activity
LUW74_RS38010	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LUW74_RS38035	COG0560	Phosphoserine phosphatase
LUW74_RS38035	COG3830	Belongs to the UPF0237 family
LUW74_RS38040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LUW74_RS38050	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS38060	COG2197	response regulator
LUW74_RS38085	COG1119	ATPase activity
LUW74_RS38130	COG2843	Capsule synthesis protein
LUW74_RS38170	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS38180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUW74_RS38185	COG2188	Transcriptional regulator
LUW74_RS38190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LUW74_RS38235	COG1280	lysine exporter protein (LysE YggA)
LUW74_RS38240	COG1522	sequence-specific DNA binding
LUW74_RS38250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUW74_RS38250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LUW74_RS38250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUW74_RS38250	COG3321	synthase
LUW74_RS38270	COG1819	glycosyl
LUW74_RS38290	COG1414	Transcriptional regulator
LUW74_RS38295	COG3339	Conserved Protein
LUW74_RS38305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LUW74_RS38325	COG1309	transcriptional regulator
LUW74_RS38380	COG1595	DNA-templated transcription, initiation
LUW74_RS38400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUW74_RS38430	COG2205	protein histidine kinase activity
LUW74_RS38435	COG0745	RESPONSE REGULATOR receiver
LUW74_RS38480	COG1595	DNA-templated transcription, initiation
LUW74_RS38510	COG2197	response regulator
LUW74_RS38530	COG0726	polysaccharide deacetylase
LUW74_RS38545	COG0477	Major facilitator Superfamily
LUW74_RS38555	COG2197	response regulator
LUW74_RS38560	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS38565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS38580	COG0300	oxidoreductase activity
LUW74_RS38595	COG1309	transcriptional regulator
LUW74_RS38600	COG2409	Drug exporters of the RND superfamily
LUW74_RS38605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS38635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LUW74_RS38650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LUW74_RS38685	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS38705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUW74_RS38730	COG3795	YCII-related domain
LUW74_RS38735	COG4941	Belongs to the sigma-70 factor family
LUW74_RS38755	COG3118	belongs to the thioredoxin family
LUW74_RS38760	COG3304	Inner membrane component domain
LUW74_RS38765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LUW74_RS38800	COG2197	response regulator
LUW74_RS38805	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LUW74_RS38895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LUW74_RS38915	COG0542	response to heat
LUW74_RS38930	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LUW74_RS38945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LUW74_RS38950	COG2151	metal-sulfur cluster biosynthetic enzyme
LUW74_RS38955	COG3396	Phenylacetate-CoA oxygenase
LUW74_RS38960	COG3460	Phenylacetate-CoA oxygenase
LUW74_RS38965	COG3396	Phenylacetate-CoA oxygenase
LUW74_RS38975	COG1309	transcriptional regulator
LUW74_RS38980	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUW74_RS39005	COG3401	FG-GAP repeat protein
LUW74_RS39010	COG3866	Pectate lyase
LUW74_RS39020	COG0701	Predicted permease
LUW74_RS39050	COG2885	chlorophyll binding
LUW74_RS39060	COG1309	transcriptional regulator
LUW74_RS39085	COG4585	Histidine kinase
LUW74_RS39090	COG2197	response regulator
LUW74_RS39105	COG2079	MmgE PrpD family protein
LUW74_RS39110	COG1609	Transcriptional regulator
LUW74_RS39115	COG0402	S-adenosylhomocysteine deaminase activity
LUW74_RS39125	COG3842	ATPase activity
LUW74_RS39135	COG1176	ABC-type spermidine putrescine transport system, permease component I
LUW74_RS39140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUW74_RS39145	COG1063	alcohol dehydrogenase
LUW74_RS39150	COG0667	Aldo Keto reductase
LUW74_RS39155	COG1309	transcriptional regulator
LUW74_RS39160	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LUW74_RS39165	COG0583	DNA-binding transcription factor activity
LUW74_RS39180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LUW74_RS39215	COG0583	DNA-binding transcription factor activity
LUW74_RS39240	COG0583	DNA-binding transcription factor activity
LUW74_RS39245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS39250	COG1024	Enoyl-CoA hydratase
LUW74_RS39305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LUW74_RS39315	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LUW74_RS39345	COG3960	tartronate-semialdehyde synthase activity
LUW74_RS39350	COG2072	flavoprotein involved in K transport
LUW74_RS39375	COG1177	transmembrane transport
LUW74_RS39380	COG3842	ATPase activity
LUW74_RS39400	COG2084	Dehydrogenase
LUW74_RS39410	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUW74_RS39430	COG3246	L-lysine catabolic process to acetate
LUW74_RS39450	COG0477	Major facilitator Superfamily
LUW74_RS39460	COG3903	Transcriptional regulator
LUW74_RS39460	COG3629	intracellular signal transduction
LUW74_RS39465	COG2319	Wd-40 repeat
LUW74_RS39465	COG4249	Peptidase C14 caspase catalytic subunit p20
LUW74_RS39485	COG0702	epimerase
LUW74_RS39525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUW74_RS39540	COG1053	succinate dehydrogenase
LUW74_RS39540	COG3976	FMN-binding domain protein
LUW74_RS39545	COG0129	dihydroxy-acid dehydratase activity
LUW74_RS39580	COG0129	dihydroxy-acid dehydratase activity
LUW74_RS39585	COG1233	COG1233 Phytoene dehydrogenase and related
LUW74_RS39595	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS39605	COG2197	response regulator
LUW74_RS39615	COG0477	Major facilitator Superfamily
LUW74_RS39635	COG2080	2 iron, 2 sulfur cluster binding
LUW74_RS39650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LUW74_RS39655	COG0640	Transcriptional regulator
LUW74_RS39660	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS39675	COG3639	organic phosphonate transmembrane transporter activity
LUW74_RS39680	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LUW74_RS39680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUW74_RS39685	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LUW74_RS39700	COG2814	Major facilitator Superfamily
LUW74_RS39705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUW74_RS39710	COG0640	Transcriptional regulator
LUW74_RS39715	COG1846	Transcriptional regulator
LUW74_RS39720	COG2226	methyltransferase
LUW74_RS39750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LUW74_RS39755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LUW74_RS39780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUW74_RS39800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUW74_RS39800	COG1754	DNA topoisomerase type I activity
LUW74_RS39805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LUW74_RS39810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LUW74_RS39815	COG1404	Belongs to the peptidase S8 family
LUW74_RS39825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LUW74_RS39840	COG1774	PSP1 C-terminal conserved region
LUW74_RS39845	COG0656	L-ascorbic acid biosynthetic process
LUW74_RS39850	COG0477	Major facilitator Superfamily
LUW74_RS39855	COG3321	synthase
LUW74_RS39855	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS39855	COG0604	alcohol dehydrogenase
LUW74_RS39860	COG0789	Transcriptional regulator
LUW74_RS39965	COG0791	NLP P60 protein
LUW74_RS39965	COG3883	PFAM NLP P60 protein
LUW74_RS39970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LUW74_RS39975	COG2027	D-alanyl-D-alanine carboxypeptidase
LUW74_RS39985	COG0037	tRNA processing
LUW74_RS39990	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LUW74_RS40000	COG0302	gtp cyclohydrolase
LUW74_RS40015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LUW74_RS40020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LUW74_RS40040	COG0649	NAD binding
LUW74_RS40065	COG2124	cytochrome p450
LUW74_RS40075	COG4585	Histidine kinase
LUW74_RS40080	COG2197	response regulator
LUW74_RS40090	COG1136	(ABC) transporter
LUW74_RS40095	COG0577	efflux transmembrane transporter activity
LUW74_RS40105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LUW74_RS40110	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LUW74_RS40125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LUW74_RS40135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LUW74_RS40140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LUW74_RS40150	COG1609	Transcriptional regulator
LUW74_RS40165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LUW74_RS40195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUW74_RS40200	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
LUW74_RS40200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUW74_RS40210	COG5434	Belongs to the glycosyl hydrolase 28 family
LUW74_RS40215	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LUW74_RS40220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LUW74_RS40235	COG1082	Xylose isomerase domain protein TIM barrel
LUW74_RS40260	COG1316	TRANSCRIPTIONal
LUW74_RS40265	COG0506	proline dehydrogenase activity
LUW74_RS40270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LUW74_RS40280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUW74_RS40285	COG1136	(ABC) transporter
LUW74_RS40290	COG1136	(ABC) transporter
LUW74_RS40290	COG0577	efflux transmembrane transporter activity
LUW74_RS40305	COG0123	including yeast histone deacetylase and acetoin utilization protein
LUW74_RS40355	COG2814	Major facilitator Superfamily
LUW74_RS40365	COG2124	cytochrome p450
LUW74_RS40375	COG0789	Transcriptional regulator
LUW74_RS40440	COG0560	Phosphoserine phosphatase
LUW74_RS40475	COG0181	hydroxymethylbilane synthase activity
LUW74_RS40485	COG0113	porphobilinogen synthase activity
LUW74_RS40505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LUW74_RS40510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LUW74_RS40530	COG0406	alpha-ribazole phosphatase activity
LUW74_RS40540	COG0785	Cytochrome C biogenesis protein
LUW74_RS40545	COG1333	cytochrome c biogenesis protein
LUW74_RS40550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUW74_RS40580	COG2226	methyltransferase
LUW74_RS40595	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUW74_RS40605	COG0649	NAD binding
LUW74_RS40620	COG1034	ATP synthesis coupled electron transport
LUW74_RS40625	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LUW74_RS40630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUW74_RS40645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LUW74_RS40660	COG0142	geranyltranstransferase activity
LUW74_RS40680	COG5002	protein histidine kinase activity
LUW74_RS40725	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS40795	COG1013	pyruvate-flavodoxin oxidoreductase activity
LUW74_RS40800	COG0674	pyruvate-flavodoxin oxidoreductase activity
LUW74_RS40800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LUW74_RS40815	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUW74_RS40825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUW74_RS40830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LUW74_RS40840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUW74_RS40845	COG0839	Belongs to the complex I subunit 6 family
LUW74_RS40850	COG0713	ATP synthesis coupled electron transport
LUW74_RS40865	COG1007	ATP synthesis coupled electron transport
LUW74_RS40870	COG0501	Belongs to the peptidase M48B family
LUW74_RS40875	COG1666	GTP binding
LUW74_RS40915	COG1674	ftsk spoiiie
LUW74_RS40945	COG0019	diaminopimelate decarboxylase activity
LUW74_RS40975	COG1132	(ABC) transporter
LUW74_RS40995	COG0681	Belongs to the peptidase S26 family
LUW74_RS41015	COG1595	DNA-templated transcription, initiation
LUW74_RS41070	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS41085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LUW74_RS41090	COG2030	dehydratase
LUW74_RS41100	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LUW74_RS41105	COG2119	membrane
LUW74_RS41110	COG1802	Transcriptional regulator
LUW74_RS41120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUW74_RS41130	COG1595	DNA-templated transcription, initiation
LUW74_RS41140	COG0436	Aminotransferase
LUW74_RS41150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUW74_RS41160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LUW74_RS41165	COG0081	regulation of translation
LUW74_RS41185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LUW74_RS41190	COG0222	ribosome binding
LUW74_RS41205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUW74_RS41210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUW74_RS41255	COG0085	RNA polymerase activity
LUW74_RS41260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LUW74_RS41270	COG0346	lactoylglutathione lyase activity
LUW74_RS41310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUW74_RS41335	COG1522	sequence-specific DNA binding
LUW74_RS41340	COG0667	Aldo Keto reductase
LUW74_RS41355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LUW74_RS41360	COG0049	tRNA binding
LUW74_RS41365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LUW74_RS41370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LUW74_RS41375	COG0051	transcription antitermination factor activity, RNA binding
LUW74_RS41380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LUW74_RS41385	COG0088	Forms part of the polypeptide exit tunnel
LUW74_RS41395	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LUW74_RS41400	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LUW74_RS41405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LUW74_RS41410	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LUW74_RS41415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LUW74_RS41420	COG0255	Belongs to the universal ribosomal protein uL29 family
LUW74_RS41425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LUW74_RS41435	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LUW74_RS41445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LUW74_RS41450	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LUW74_RS41455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LUW74_RS41460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LUW74_RS41465	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LUW74_RS41475	COG0200	Binds to the 23S rRNA
LUW74_RS41480	COG0201	protein transport
LUW74_RS41485	COG0563	adenylate kinase activity
LUW74_RS41500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LUW74_RS41510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LUW74_RS41515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LUW74_RS41520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LUW74_RS41525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LUW74_RS41530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LUW74_RS41535	COG0202	RNA polymerase activity
LUW74_RS41540	COG0203	ribosomal protein L17
LUW74_RS41545	COG0101	tRNA pseudouridine synthase activity
LUW74_RS41560	COG2340	Cysteine-rich secretory protein family
LUW74_RS41565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LUW74_RS41570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LUW74_RS41575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUW74_RS41595	COG1131	(ABC) transporter
LUW74_RS41615	COG2197	response regulator
LUW74_RS41620	COG4585	Histidine kinase
LUW74_RS41625	COG2409	Drug exporters of the RND superfamily
LUW74_RS41630	COG3831	ATPase activity
LUW74_RS41640	COG1072	(Pantothenic acid kinase))
LUW74_RS41645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUW74_RS41685	COG1063	alcohol dehydrogenase
LUW74_RS41690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LUW74_RS41700	COG0802	atpase or kinase
LUW74_RS41710	COG0456	acetyltransferase
LUW74_RS41710	COG1214	PFAM Peptidase M22, glycoprotease
LUW74_RS41720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LUW74_RS41740	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LUW74_RS41745	COG0459	protein refolding
LUW74_RS41750	COG1595	DNA-templated transcription, initiation
LUW74_RS41775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LUW74_RS41800	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS41845	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
LUW74_RS41850	COG1216	Glycosyl transferase, family 2
LUW74_RS41855	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LUW74_RS41860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LUW74_RS41865	COG0500	methyltransferase
LUW74_RS41890	COG0791	NLP P60 protein
LUW74_RS41890	COG1388	LysM domain
LUW74_RS41890	COG3103	Sh3 type 3 domain protein
LUW74_RS41935	COG2197	response regulator
LUW74_RS41965	COG2376	Dihydroxyacetone kinase
LUW74_RS41970	COG1461	Dihydroxyacetone kinase
LUW74_RS41975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUW74_RS41975	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LUW74_RS41975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LUW74_RS42025	COG1764	response to oxidative stress
LUW74_RS42030	COG0641	radical SAM
LUW74_RS42075	COG2318	DinB family
LUW74_RS42095	COG0778	Nitroreductase
LUW74_RS42100	COG5650	phosphatidylinositol metabolic process
LUW74_RS42105	COG4585	Histidine kinase
LUW74_RS42110	COG2197	response regulator
LUW74_RS42140	COG0180	Tryptophanyl-tRNA synthetase
LUW74_RS42165	COG0504	CTP synthase activity
LUW74_RS42185	COG3384	dioxygenase
LUW74_RS42195	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LUW74_RS42220	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS42230	COG0588	phosphoglycerate mutase activity
LUW74_RS42240	COG2814	Major facilitator Superfamily
LUW74_RS42265	COG0745	RESPONSE REGULATOR receiver
LUW74_RS42285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LUW74_RS42290	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS42315	COG4941	Belongs to the sigma-70 factor family
LUW74_RS42325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUW74_RS42330	COG4941	Belongs to the sigma-70 factor family
LUW74_RS42355	COG1733	regulation of RNA biosynthetic process
LUW74_RS42370	COG1917	Cupin 2, conserved barrel domain protein
LUW74_RS42370	COG4977	sequence-specific DNA binding
LUW74_RS42395	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LUW74_RS42420	COG0477	Major facilitator Superfamily
LUW74_RS42440	COG1404	Belongs to the peptidase S8 family
LUW74_RS42470	COG1695	Transcriptional regulator
LUW74_RS42480	COG1595	DNA-templated transcription, initiation
LUW74_RS42495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LUW74_RS42525	COG0459	protein refolding
LUW74_RS42560	COG1061	Type III restriction enzyme res subunit
LUW74_RS42575	COG1309	transcriptional regulator
LUW74_RS42605	COG2814	Major facilitator Superfamily
LUW74_RS42635	COG2814	Major facilitator Superfamily
LUW74_RS42640	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LUW74_RS42685	COG0259	pyridoxamine-phosphate oxidase activity
LUW74_RS42695	COG1573	uracil-dna glycosylase
LUW74_RS42715	COG2226	methyltransferase
LUW74_RS42735	COG0183	Belongs to the thiolase family
LUW74_RS42740	COG1024	Enoyl-CoA hydratase
LUW74_RS42770	COG0640	Transcriptional regulator
LUW74_RS42810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LUW74_RS42820	COG2197	response regulator
LUW74_RS42850	COG2207	Transcriptional regulator
LUW74_RS42860	COG4585	Histidine kinase
LUW74_RS42910	COG1309	transcriptional regulator
LUW74_RS42930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS42945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LUW74_RS42960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUW74_RS42985	COG1725	Transcriptional regulator
LUW74_RS43000	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS43020	COG0018	arginyl-trna synthetase
LUW74_RS43025	COG0416	fatty acid biosynthetic process
LUW74_RS43065	COG1881	PFAM PEBP family protein
LUW74_RS43070	COG0395	ABC-type sugar transport system, permease component
LUW74_RS43075	COG1175	transmembrane transport
LUW74_RS43080	COG3842	ATPase activity
LUW74_RS43090	COG1134	teichoic acid transport
LUW74_RS43090	COG1388	LysM domain
LUW74_RS43100	COG1597	lipid kinase activity
LUW74_RS43110	COG2720	vancomycin resistance protein
LUW74_RS43150	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS43155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUW74_RS43170	COG0181	hydroxymethylbilane synthase activity
LUW74_RS43195	COG0488	(ABC) transporter
LUW74_RS43200	COG0442	prolyl-tRNA aminoacylation
LUW74_RS43205	COG0442	prolyl-tRNA aminoacylation
LUW74_RS43235	COG1595	DNA-templated transcription, initiation
LUW74_RS43255	COG1366	Belongs to the anti-sigma-factor antagonist family
LUW74_RS43255	COG2172	sigma factor antagonist activity
LUW74_RS43255	COG2208	phosphoserine phosphatase activity
LUW74_RS43290	COG0612	Peptidase, M16
LUW74_RS43295	COG1366	Belongs to the anti-sigma-factor antagonist family
LUW74_RS43370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LUW74_RS43375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS43380	COG4941	Belongs to the sigma-70 factor family
LUW74_RS43420	COG0577	efflux transmembrane transporter activity
LUW74_RS43420	COG1136	(ABC) transporter
LUW74_RS43440	COG5564	TIM-barrel signal transduction protein
LUW74_RS43460	COG1252	NADH dehydrogenase
LUW74_RS43465	COG1595	DNA-templated transcription, initiation
LUW74_RS43475	COG3012	SEC-C Motif Domain Protein
LUW74_RS43500	COG4941	Belongs to the sigma-70 factor family
LUW74_RS43510	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LUW74_RS43515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LUW74_RS43520	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LUW74_RS43550	COG1309	transcriptional regulator
LUW74_RS43565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUW74_RS43570	COG0747	negative chemotaxis
LUW74_RS43580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUW74_RS43585	COG0444	Belongs to the ABC transporter superfamily
LUW74_RS43590	COG4608	Belongs to the ABC transporter superfamily
LUW74_RS43595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUW74_RS43600	COG1414	Transcriptional regulator
LUW74_RS43605	COG2080	2 iron, 2 sulfur cluster binding
LUW74_RS43610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LUW74_RS43615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LUW74_RS43630	COG3384	dioxygenase
LUW74_RS43645	COG0579	oxidoreductase
LUW74_RS43655	COG1396	sequence-specific DNA binding
LUW74_RS43660	COG0477	Major facilitator Superfamily
LUW74_RS43665	COG1228	amidohydrolase
LUW74_RS43680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUW74_RS43680	COG0515	serine threonine protein kinase
LUW74_RS43725	COG3344	reverse transcriptase
LUW74_RS43735	COG0714	Associated with various cellular activities
LUW74_RS43860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUW74_RS43865	COG0195	Participates in both transcription termination and antitermination
LUW74_RS43900	COG1876	peptidase activity
LUW74_RS43905	COG1970	mechanosensitive ion channel activity
LUW74_RS43920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LUW74_RS43925	COG2409	Drug exporters of the RND superfamily
LUW74_RS43935	COG3263	regulation of cellular component size
LUW74_RS43945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LUW74_RS43950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LUW74_RS43960	COG0315	cyclic pyranopterin monophosphate synthase activity
LUW74_RS43965	COG0521	Mo-molybdopterin cofactor biosynthetic process
LUW74_RS43970	COG0215	cysteine-tRNA ligase activity
LUW74_RS43985	COG0477	Major facilitator Superfamily
LUW74_RS43990	COG3795	YCII-related domain
LUW74_RS44005	COG2222	sugar isomerase
LUW74_RS44040	COG0154	amidase activity
LUW74_RS44065	COG1349	DNA-binding transcription factor activity
LUW74_RS44085	COG0745	RESPONSE REGULATOR receiver
LUW74_RS44090	COG2205	protein histidine kinase activity
LUW74_RS44115	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS44120	COG0667	Aldo Keto reductase
LUW74_RS44140	COG0375	protein maturation
LUW74_RS44150	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LUW74_RS44190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LUW74_RS44200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LUW74_RS44225	COG1672	PFAM Archaeal ATPase
LUW74_RS44225	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LUW74_RS44245	COG2508	Transcriptional regulator
LUW74_RS44260	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS44265	COG0300	oxidoreductase activity
LUW74_RS44270	COG3835	regulator
LUW74_RS44295	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LUW74_RS44305	COG1657	PFAM Prenyltransferase squalene oxidase
LUW74_RS44325	COG1132	(ABC) transporter
LUW74_RS44330	COG1132	(ABC) transporter
LUW74_RS44345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUW74_RS44355	COG0248	Ppx GppA phosphatase
LUW74_RS44360	COG0701	Predicted permease
LUW74_RS44385	COG3485	protocatechuate 3,4-dioxygenase
LUW74_RS44400	COG0778	Nitroreductase
LUW74_RS44420	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUW74_RS44435	COG1063	alcohol dehydrogenase
LUW74_RS44440	COG1414	Transcriptional regulator
LUW74_RS44450	COG1024	Enoyl-CoA hydratase
LUW74_RS44460	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS44465	COG0402	S-adenosylhomocysteine deaminase activity
LUW74_RS44485	COG3181	Tripartite tricarboxylate transporter family receptor
LUW74_RS44495	COG0028	Belongs to the TPP enzyme family
LUW74_RS44500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LUW74_RS44515	COG2234	aminopeptidase activity
LUW74_RS44530	COG0667	Aldo Keto reductase
LUW74_RS44545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUW74_RS44575	COG0515	serine threonine protein kinase
LUW74_RS44575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUW74_RS44650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LUW74_RS44655	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUW74_RS44660	COG0022	dehydrogenase e1 component
LUW74_RS44675	COG1522	sequence-specific DNA binding
LUW74_RS44685	COG1802	Transcriptional regulator
LUW74_RS44695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUW74_RS44705	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS44740	COG1473	amidohydrolase
LUW74_RS44755	COG0745	RESPONSE REGULATOR receiver
LUW74_RS44760	COG0018	arginyl-trna synthetase
LUW74_RS44765	COG0019	diaminopimelate decarboxylase activity
LUW74_RS44770	COG0460	homoserine dehydrogenase
LUW74_RS44775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LUW74_RS44780	COG0083	homoserine kinase activity
LUW74_RS44795	COG2197	response regulator
LUW74_RS44800	COG0254	rRNA binding
LUW74_RS44805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LUW74_RS44810	COG2890	protein-(glutamine-N5) methyltransferase activity
LUW74_RS44830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LUW74_RS44850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LUW74_RS44855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LUW74_RS44860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LUW74_RS44865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LUW74_RS44870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LUW74_RS44875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LUW74_RS44880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LUW74_RS44920	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS44940	COG0702	epimerase
LUW74_RS44950	COG1994	Peptidase M50
LUW74_RS44995	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LUW74_RS45015	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUW74_RS45045	COG0346	lactoylglutathione lyase activity
LUW74_RS45050	COG0183	Belongs to the thiolase family
LUW74_RS45065	COG2814	Major facilitator Superfamily
LUW74_RS45100	COG1678	Uncharacterized ACR, COG1678
LUW74_RS45120	COG3265	gluconokinase activity
LUW74_RS45125	COG1335	isochorismatase
LUW74_RS45135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LUW74_RS45180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LUW74_RS45185	COG1234	tRNA 3'-trailer cleavage
LUW74_RS45190	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LUW74_RS45195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LUW74_RS45205	COG1595	DNA-templated transcription, initiation
LUW74_RS45235	COG0477	Major facilitator Superfamily
LUW74_RS45260	COG1486	melibiose metabolic process
LUW74_RS45290	COG0277	FAD linked oxidase domain protein
LUW74_RS45300	COG3290	protein histidine kinase activity
LUW74_RS45305	COG3290	protein histidine kinase activity
LUW74_RS45310	COG4565	transcriptional regulatory protein
LUW74_RS45320	COG0183	Belongs to the thiolase family
LUW74_RS45350	COG1280	lysine exporter protein (LysE YggA)
LUW74_RS45385	COG1760	l-serine dehydratase
LUW74_RS45390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LUW74_RS45395	COG0509	glycine decarboxylation via glycine cleavage system
LUW74_RS45400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LUW74_RS45405	COG0750	zinc metalloprotease
LUW74_RS45410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LUW74_RS45420	COG1793	dna ligase
LUW74_RS45445	COG1309	transcriptional regulator
LUW74_RS45460	COG1309	transcriptional regulator
LUW74_RS45480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUW74_RS45580	COG1309	transcriptional regulator
LUW74_RS45600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUW74_RS45645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LUW74_RS45670	COG0204	Acyl-transferase
LUW74_RS45680	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LUW74_RS45695	COG3634	alkyl hydroperoxide reductase activity
LUW74_RS45715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LUW74_RS45715	COG2508	Transcriptional regulator
LUW74_RS45720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUW74_RS45760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUW74_RS45765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUW74_RS45765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUW74_RS45780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUW74_RS45850	COG1116	anion transmembrane transporter activity
LUW74_RS45860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUW74_RS45865	COG1609	Transcriptional regulator
LUW74_RS45925	COG2080	2 iron, 2 sulfur cluster binding
LUW74_RS45930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LUW74_RS45935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LUW74_RS45940	COG1620	l-lactate permease
LUW74_RS45985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LUW74_RS45995	COG1053	succinate dehydrogenase
LUW74_RS46010	COG0346	lactoylglutathione lyase activity
LUW74_RS46030	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS46090	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS46095	COG0583	DNA-binding transcription factor activity
LUW74_RS46110	COG1309	transcriptional regulator
LUW74_RS46190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUW74_RS46190	COG0515	serine threonine protein kinase
LUW74_RS46205	COG0028	Belongs to the TPP enzyme family
LUW74_RS46220	COG1414	Transcriptional regulator
LUW74_RS46225	COG3321	synthase
LUW74_RS46225	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS46225	COG0604	alcohol dehydrogenase
LUW74_RS46250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LUW74_RS46275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LUW74_RS46285	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LUW74_RS46295	COG4208	sulfate ABC transporter
LUW74_RS46305	COG1959	2 iron, 2 sulfur cluster binding
LUW74_RS46310	COG1595	DNA-templated transcription, initiation
LUW74_RS46330	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS46335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS46420	COG2267	carboxylic ester hydrolase activity
LUW74_RS46465	COG2171	N-acyltransferase activity
LUW74_RS46475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUW74_RS46480	COG1611	Belongs to the LOG family
LUW74_RS46490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUW74_RS46495	COG1609	Transcriptional regulator
LUW74_RS46500	COG0583	DNA-binding transcription factor activity
LUW74_RS46510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUW74_RS46515	COG1309	transcriptional regulator
LUW74_RS46520	COG1131	(ABC) transporter
LUW74_RS46525	COG3559	Exporter of polyketide antibiotics
LUW74_RS46530	COG3559	Exporter of polyketide antibiotics
LUW74_RS46535	COG1611	Belongs to the LOG family
LUW74_RS46540	COG0028	Belongs to the TPP enzyme family
LUW74_RS46545	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS46550	COG0483	inositol monophosphate 1-phosphatase activity
LUW74_RS46575	COG2818	Glycosylase
LUW74_RS46590	COG1024	Enoyl-CoA hydratase
LUW74_RS46600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUW74_RS46610	COG4122	O-methyltransferase activity
LUW74_RS46630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUW74_RS46645	COG1846	Transcriptional regulator
LUW74_RS46655	COG2239	Acts as a magnesium transporter
LUW74_RS46690	COG0613	PHP domain protein
LUW74_RS46745	COG4585	Histidine kinase
LUW74_RS46755	COG2409	Drug exporters of the RND superfamily
LUW74_RS46795	COG3321	synthase
LUW74_RS46795	COG0604	alcohol dehydrogenase
LUW74_RS46820	COG0702	epimerase
LUW74_RS46835	COG0513	Belongs to the DEAD box helicase family
LUW74_RS46865	COG1793	dna ligase
LUW74_RS46865	COG3285	dna ligase
LUW74_RS46870	COG1793	dna ligase
LUW74_RS46870	COG3285	dna ligase
LUW74_RS46875	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LUW74_RS46885	COG2409	Drug exporters of the RND superfamily
LUW74_RS46895	COG5002	protein histidine kinase activity
LUW74_RS46900	COG0745	RESPONSE REGULATOR receiver
LUW74_RS46925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUW74_RS46960	COG0210	DNA helicase
LUW74_RS46965	COG0210	DNA helicase
LUW74_RS46970	COG2226	methyltransferase
LUW74_RS46980	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS46995	COG0019	diaminopimelate decarboxylase activity
LUW74_RS47010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LUW74_RS47065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LUW74_RS47120	COG3480	Lon protease (S16) C-terminal proteolytic domain
LUW74_RS47130	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS47145	COG1012	belongs to the aldehyde dehydrogenase family
LUW74_RS47170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS47180	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS47185	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS47195	COG0300	oxidoreductase activity
LUW74_RS47205	COG1309	transcriptional regulator
LUW74_RS47225	COG0483	inositol monophosphate 1-phosphatase activity
LUW74_RS47235	COG0277	FAD linked oxidase domain protein
LUW74_RS47255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LUW74_RS47275	COG2135	peptidase activity
LUW74_RS47290	COG1595	DNA-templated transcription, initiation
LUW74_RS47295	COG5662	AntiSigma factor
LUW74_RS47305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUW74_RS47305	COG2199	diguanylate cyclase activity
LUW74_RS47310	COG2199	diguanylate cyclase activity
LUW74_RS47310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUW74_RS47365	COG0277	FAD linked oxidase domain protein
LUW74_RS47370	COG2205	protein histidine kinase activity
LUW74_RS47375	COG0745	RESPONSE REGULATOR receiver
LUW74_RS47390	COG0577	efflux transmembrane transporter activity
LUW74_RS47390	COG1136	(ABC) transporter
LUW74_RS47395	COG0577	efflux transmembrane transporter activity
LUW74_RS47395	COG1136	(ABC) transporter
LUW74_RS47420	COG0515	serine threonine protein kinase
LUW74_RS47485	COG1201	RNA secondary structure unwinding
LUW74_RS47490	COG3629	intracellular signal transduction
LUW74_RS47490	COG3903	Transcriptional regulator
LUW74_RS47585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LUW74_RS47590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUW74_RS47615	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LUW74_RS47620	COG0583	DNA-binding transcription factor activity
LUW74_RS47655	COG2172	sigma factor antagonist activity
LUW74_RS47685	COG0156	8-amino-7-oxononanoate synthase activity
LUW74_RS47690	COG2188	Transcriptional regulator
LUW74_RS47705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUW74_RS47710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LUW74_RS47730	COG0439	Biotin carboxylase
LUW74_RS47755	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS47765	COG0657	acetylesterase activity
LUW74_RS47770	COG2186	Transcriptional regulator
LUW74_RS47780	COG1175	transmembrane transport
LUW74_RS47795	COG4948	Mandelate Racemase Muconate Lactonizing
LUW74_RS47815	COG2945	thiolester hydrolase activity
LUW74_RS47815	COG0596	Alpha beta hydrolase
LUW74_RS47840	COG4585	Histidine kinase
LUW74_RS47850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUW74_RS47855	COG0281	malic enzyme
LUW74_RS47860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUW74_RS47865	COG0765	amino acid transport
LUW74_RS47875	COG0604	alcohol dehydrogenase
LUW74_RS47880	COG1695	Transcriptional regulator
LUW74_RS47915	COG0435	Glutathione S-transferase
LUW74_RS47930	COG1028	Short-chain dehydrogenase reductase Sdr
LUW74_RS47935	COG1024	Enoyl-CoA hydratase
LUW74_RS47950	COG2018	Roadblock/LC7 domain
LUW74_RS47970	COG2018	Roadblock/LC7 domain
LUW74_RS47985	COG1940	carbohydrate kinase activity
LUW74_RS47990	COG1129	ABC transporter
LUW74_RS47995	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUW74_RS48000	COG4213	ABC transporter substrate-binding protein
LUW74_RS48005	COG0673	inositol 2-dehydrogenase activity
LUW74_RS48070	COG2226	methyltransferase
LUW74_RS48075	COG0438	transferase activity, transferring glycosyl groups
LUW74_RS48080	COG2124	cytochrome p450
LUW74_RS48085	COG2124	cytochrome p450
LUW74_RS48110	COG2124	cytochrome p450
LUW74_RS48115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUW74_RS48125	COG2124	cytochrome p450
LUW74_RS48130	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS48150	COG3835	regulator
LUW74_RS48185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LUW74_RS48190	COG3622	Belongs to the hyi family
LUW74_RS48195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LUW74_RS48200	COG4266	Belongs to the allantoicase family
LUW74_RS48235	COG1309	transcriptional regulator
LUW74_RS48240	COG0318	PFAM AMP-dependent synthetase and ligase
LUW74_RS48245	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS48250	COG1960	acyl-CoA dehydrogenase activity
LUW74_RS48260	COG0076	glutamate decarboxylase activity
LUW74_RS48265	COG1309	transcriptional regulator
LUW74_RS48270	COG0477	Major facilitator Superfamily
LUW74_RS48285	COG3572	ergothioneine biosynthetic process
LUW74_RS48290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUW74_RS48295	COG0121	glutamine amidotransferase
LUW74_RS48300	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LUW74_RS48310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LUW74_RS48325	COG1609	Transcriptional regulator
LUW74_RS48330	COG2986	histidine ammonia-lyase
LUW74_RS48335	COG0517	IMP dehydrogenase activity
LUW74_RS48335	COG1125	glycine betaine transport
LUW74_RS48340	COG1174	glycine betaine transport
LUW74_RS48345	COG1174	glycine betaine transport
LUW74_RS48370	COG4106	trans-aconitate 2-methyltransferase activity
LUW74_RS48385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUW74_RS48400	COG1136	(ABC) transporter
LUW74_RS48460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUW74_RS48460	COG3320	Male sterility
LUW74_RS48475	COG2986	histidine ammonia-lyase
LUW74_RS48480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LUW74_RS48535	COG1228	amidohydrolase
LUW74_RS48540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LUW74_RS48545	COG0616	signal peptide processing
LUW74_RS48560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position