locus-tag	class	description
HUT06_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUT06_RS00010	COG0592	DNA-directed DNA polymerase activity
HUT06_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT06_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT06_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT06_RS00030	COG0187	DNA topoisomerase II activity
HUT06_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT06_RS00040	COG3266	domain, Protein
HUT06_RS00075	COG0697	spore germination
HUT06_RS00085	COG0300	oxidoreductase activity
HUT06_RS00110	COG0640	Transcriptional regulator
HUT06_RS00140	COG1294	oxidase, subunit
HUT06_RS00145	COG1271	oxidase subunit
HUT06_RS00155	COG0151	Belongs to the GarS family
HUT06_RS00165	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT06_RS00170	COG1834	amidinotransferase
HUT06_RS00220	COG0513	Belongs to the DEAD box helicase family
HUT06_RS00240	COG0705	Rhomboid family
HUT06_RS00255	COG3764	Sortase (surface protein transpeptidase)
HUT06_RS00265	COG0515	serine threonine protein kinase
HUT06_RS00270	COG0515	serine threonine protein kinase
HUT06_RS00275	COG0768	penicillin binding
HUT06_RS00290	COG1716	ATPase activity
HUT06_RS00350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT06_RS00415	COG2378	regulation of single-species biofilm formation
HUT06_RS00455	COG3467	pyridoxamine 5'-phosphate
HUT06_RS00465	COG2814	Major facilitator Superfamily
HUT06_RS00475	COG4221	oxidoreductase activity
HUT06_RS00535	COG0477	Major facilitator Superfamily
HUT06_RS00575	COG1733	regulation of RNA biosynthetic process
HUT06_RS00620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT06_RS00685	COG0583	DNA-binding transcription factor activity
HUT06_RS00690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT06_RS00700	COG1309	transcriptional regulator
HUT06_RS00715	COG1595	DNA-templated transcription, initiation
HUT06_RS00735	COG1902	pentaerythritol trinitrate reductase activity
HUT06_RS00765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT06_RS00815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT06_RS00825	COG5002	protein histidine kinase activity
HUT06_RS00835	COG2235	arginine
HUT06_RS00870	COG0745	RESPONSE REGULATOR receiver
HUT06_RS00875	COG5002	protein histidine kinase activity
HUT06_RS00900	COG5650	phosphatidylinositol metabolic process
HUT06_RS00915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT06_RS00930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT06_RS00935	COG0561	phosphatase activity
HUT06_RS00945	COG0604	alcohol dehydrogenase
HUT06_RS01025	COG1595	DNA-templated transcription, initiation
HUT06_RS01030	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS01065	COG4585	Histidine kinase
HUT06_RS01070	COG2197	response regulator
HUT06_RS01075	COG0515	serine threonine protein kinase
HUT06_RS01080	COG0783	Belongs to the Dps family
HUT06_RS01085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT06_RS01090	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT06_RS01095	COG2080	2 iron, 2 sulfur cluster binding
HUT06_RS01105	COG1595	DNA-templated transcription, initiation
HUT06_RS01115	COG0604	alcohol dehydrogenase
HUT06_RS01125	COG1131	(ABC) transporter
HUT06_RS01135	COG0745	RESPONSE REGULATOR receiver
HUT06_RS01140	COG2205	protein histidine kinase activity
HUT06_RS01145	COG2814	Major facilitator Superfamily
HUT06_RS01155	COG1595	DNA-templated transcription, initiation
HUT06_RS01195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT06_RS01255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS01365	COG3693	PFAM glycoside hydrolase, family 10
HUT06_RS01370	COG0667	Aldo Keto reductase
HUT06_RS01450	COG3920	Histidine kinase
HUT06_RS01455	COG2207	Transcriptional regulator
HUT06_RS01485	COG1401	restriction endodeoxyribonuclease activity
HUT06_RS01495	COG2319	Wd-40 repeat
HUT06_RS01495	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT06_RS01510	COG3920	Histidine kinase
HUT06_RS01530	COG1595	DNA-templated transcription, initiation
HUT06_RS01560	COG1959	2 iron, 2 sulfur cluster binding
HUT06_RS01565	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS01575	COG1584	GPR1 FUN34 yaaH family protein
HUT06_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS01585	COG2267	carboxylic ester hydrolase activity
HUT06_RS01590	COG2205	protein histidine kinase activity
HUT06_RS01595	COG0745	RESPONSE REGULATOR receiver
HUT06_RS01615	COG0514	ATP-dependent DNA helicase (RecQ)
HUT06_RS01620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT06_RS01630	COG1950	PFAM Membrane protein of
HUT06_RS01655	COG1253	flavin adenine dinucleotide binding
HUT06_RS01660	COG1253	flavin adenine dinucleotide binding
HUT06_RS01670	COG0515	serine threonine protein kinase
HUT06_RS01675	COG0675	Transposase, IS605 OrfB family
HUT06_RS01700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS01710	COG0204	Acyl-transferase
HUT06_RS01710	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS01725	COG2268	Band 7 protein
HUT06_RS01740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT06_RS01750	COG1846	Transcriptional regulator
HUT06_RS01755	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT06_RS01760	COG0667	Aldo Keto reductase
HUT06_RS01775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT06_RS01785	COG0633	Ferredoxin
HUT06_RS01785	COG3217	Mosc domain protein beta barrel domain protein
HUT06_RS01790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT06_RS01795	COG0151	Belongs to the GarS family
HUT06_RS01800	COG0598	Magnesium transport protein CorA
HUT06_RS01810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT06_RS01845	COG0586	Pfam SNARE associated Golgi protein
HUT06_RS01855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT06_RS01870	COG1432	Conserved Protein
HUT06_RS01895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT06_RS01905	COG1846	Transcriptional regulator
HUT06_RS01945	COG0542	response to heat
HUT06_RS01950	COG0789	Transcriptional regulator
HUT06_RS01955	COG0484	heat shock protein binding
HUT06_RS01960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT06_RS01965	COG0443	Heat shock 70 kDa protein
HUT06_RS01980	COG2197	response regulator
HUT06_RS01985	COG4585	Histidine kinase
HUT06_RS01995	COG1404	Belongs to the peptidase S8 family
HUT06_RS02000	COG1595	DNA-templated transcription, initiation
HUT06_RS02010	COG1595	DNA-templated transcription, initiation
HUT06_RS02025	COG0477	Major facilitator Superfamily
HUT06_RS02030	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT06_RS02035	COG0183	Belongs to the thiolase family
HUT06_RS02055	COG2181	nitrate reductase activity
HUT06_RS02055	COG0247	lactate metabolic process
HUT06_RS02060	COG3629	intracellular signal transduction
HUT06_RS02060	COG3903	Transcriptional regulator
HUT06_RS02080	COG4176	ABC-type proline glycine betaine transport system permease component
HUT06_RS02090	COG0717	Belongs to the dCTP deaminase family
HUT06_RS02175	COG0494	nUDIX hydrolase
HUT06_RS02245	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HUT06_RS02300	COG1595	DNA-templated transcription, initiation
HUT06_RS02325	COG2814	Major facilitator Superfamily
HUT06_RS02345	COG1136	(ABC) transporter
HUT06_RS02370	COG3304	Inner membrane component domain
HUT06_RS02375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT06_RS02380	COG0726	polysaccharide deacetylase
HUT06_RS02385	COG1982	Orn Lys Arg decarboxylase major
HUT06_RS02400	COG1285	pathogenesis
HUT06_RS02420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUT06_RS02435	COG3850	Histidine kinase
HUT06_RS02435	COG5002	protein histidine kinase activity
HUT06_RS02450	COG1316	TRANSCRIPTIONal
HUT06_RS02455	COG4977	sequence-specific DNA binding
HUT06_RS02475	COG0242	peptide deformylase activity
HUT06_RS02530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT06_RS02535	COG0028	Belongs to the TPP enzyme family
HUT06_RS02570	COG2188	Transcriptional regulator
HUT06_RS02585	COG3547	Transposase (IS116 IS110 IS902 family)
HUT06_RS02600	COG2207	Transcriptional regulator
HUT06_RS02655	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT06_RS02690	COG4172	Belongs to the ABC transporter superfamily
HUT06_RS02700	COG0601	transmembrane transport
HUT06_RS02740	COG1090	epimerase
HUT06_RS02745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT06_RS02750	COG0542	response to heat
HUT06_RS02765	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HUT06_RS02775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT06_RS02780	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT06_RS02785	COG3396	Phenylacetate-CoA oxygenase
HUT06_RS02790	COG3460	Phenylacetate-CoA oxygenase
HUT06_RS02795	COG3396	Phenylacetate-CoA oxygenase
HUT06_RS02800	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS02800	COG2030	dehydratase
HUT06_RS02805	COG1309	transcriptional regulator
HUT06_RS02850	COG1742	UPF0060 membrane protein
HUT06_RS02855	COG0789	Transcriptional regulator
HUT06_RS02860	COG2837	iron assimilation
HUT06_RS02875	COG3401	FG-GAP repeat protein
HUT06_RS02890	COG1473	amidohydrolase
HUT06_RS02895	COG2860	membrane
HUT06_RS02915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT06_RS02940	COG3119	arylsulfatase activity
HUT06_RS02975	COG1024	Enoyl-CoA hydratase
HUT06_RS02980	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS02990	COG3976	FMN-binding domain protein
HUT06_RS02990	COG1053	succinate dehydrogenase
HUT06_RS03035	COG2197	response regulator
HUT06_RS03040	COG4585	Histidine kinase
HUT06_RS03045	COG2409	Drug exporters of the RND superfamily
HUT06_RS03095	COG3883	PFAM NLP P60 protein
HUT06_RS03095	COG0791	NLP P60 protein
HUT06_RS03110	COG0667	Aldo Keto reductase
HUT06_RS03115	COG3321	synthase
HUT06_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS03115	COG0604	alcohol dehydrogenase
HUT06_RS03130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS03150	COG0574	Belongs to the PEP-utilizing enzyme family
HUT06_RS03150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT06_RS03180	COG1024	Enoyl-CoA hydratase
HUT06_RS03185	COG4585	Histidine kinase
HUT06_RS03190	COG2197	response regulator
HUT06_RS03200	COG1136	(ABC) transporter
HUT06_RS03200	COG0577	efflux transmembrane transporter activity
HUT06_RS03210	COG3629	intracellular signal transduction
HUT06_RS03210	COG3903	Transcriptional regulator
HUT06_RS03240	COG0477	Major facilitator Superfamily
HUT06_RS03255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT06_RS03260	COG1234	tRNA 3'-trailer cleavage
HUT06_RS03285	COG2309	aminopeptidase activity
HUT06_RS03290	COG0596	Alpha beta hydrolase
HUT06_RS03295	COG1802	Transcriptional regulator
HUT06_RS03300	COG1335	isochorismatase
HUT06_RS03320	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS03335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS03340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT06_RS03405	COG3328	transposase activity
HUT06_RS03420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT06_RS03440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT06_RS03440	COG1754	DNA topoisomerase type I activity
HUT06_RS03445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT06_RS03450	COG0470	DNA polymerase III
HUT06_RS03465	COG1595	DNA-templated transcription, initiation
HUT06_RS03475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT06_RS03495	COG1774	PSP1 C-terminal conserved region
HUT06_RS03500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT06_RS03500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT06_RS03540	COG1136	(ABC) transporter
HUT06_RS03540	COG0577	efflux transmembrane transporter activity
HUT06_RS03545	COG0577	efflux transmembrane transporter activity
HUT06_RS03545	COG1136	(ABC) transporter
HUT06_RS03575	COG0477	Major facilitator Superfamily
HUT06_RS03600	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
HUT06_RS03610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT06_RS03630	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS03655	COG0492	ferredoxin-NADP+ reductase activity
HUT06_RS03720	COG1846	Transcriptional regulator
HUT06_RS03740	COG2226	methyltransferase
HUT06_RS03775	COG1802	Transcriptional regulator
HUT06_RS03780	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS03785	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS03800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT06_RS03820	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS03830	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HUT06_RS03845	COG1113	amino acid transport
HUT06_RS03855	COG0584	glycerophosphoryl diester phosphodiesterase
HUT06_RS03860	COG0583	DNA-binding transcription factor activity
HUT06_RS03865	COG2205	protein histidine kinase activity
HUT06_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS03900	COG0583	DNA-binding transcription factor activity
HUT06_RS03930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS03980	COG0556	nucleotide-excision repair
HUT06_RS04005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT06_RS04020	COG1309	transcriptional regulator
HUT06_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS04080	COG1879	ABC-type sugar transport system periplasmic component
HUT06_RS04090	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS04095	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS04100	COG0515	serine threonine protein kinase
HUT06_RS04100	COG2815	serine threonine protein kinase
HUT06_RS04125	COG3540	Alkaline phosphatase
HUT06_RS04190	COG0577	efflux transmembrane transporter activity
HUT06_RS04190	COG1136	(ABC) transporter
HUT06_RS04200	COG0583	DNA-binding transcription factor activity
HUT06_RS04210	COG1595	DNA-templated transcription, initiation
HUT06_RS04280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUT06_RS04290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUT06_RS04320	COG4977	sequence-specific DNA binding
HUT06_RS04335	COG0737	Belongs to the 5'-nucleotidase family
HUT06_RS04345	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS04350	COG1024	Enoyl-CoA hydratase
HUT06_RS04360	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS04375	COG2197	response regulator
HUT06_RS04400	COG3275	phosphorelay sensor kinase activity
HUT06_RS04415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT06_RS04425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT06_RS04440	COG0673	inositol 2-dehydrogenase activity
HUT06_RS04445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUT06_RS04455	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS04480	COG0463	Glycosyl transferase, family 2
HUT06_RS04495	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS04500	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS04515	COG1414	Transcriptional regulator
HUT06_RS04545	COG0583	DNA-binding transcription factor activity
HUT06_RS04565	COG1063	alcohol dehydrogenase
HUT06_RS04585	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT06_RS04605	COG2409	Drug exporters of the RND superfamily
HUT06_RS04615	COG1140	nitrate reductase beta subunit
HUT06_RS04635	COG1131	(ABC) transporter
HUT06_RS04645	COG4585	Histidine kinase
HUT06_RS04650	COG2197	response regulator
HUT06_RS04655	COG1309	transcriptional regulator
HUT06_RS04660	COG2409	Drug exporters of the RND superfamily
HUT06_RS04665	COG2197	response regulator
HUT06_RS04670	COG4585	Histidine kinase
HUT06_RS04680	COG0577	efflux transmembrane transporter activity
HUT06_RS04680	COG1136	(ABC) transporter
HUT06_RS04690	COG0531	amino acid
HUT06_RS04805	COG2267	carboxylic ester hydrolase activity
HUT06_RS04825	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS04835	COG1053	succinate dehydrogenase
HUT06_RS04835	COG3976	FMN-binding domain protein
HUT06_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS04850	COG1053	succinate dehydrogenase
HUT06_RS04860	COG1053	succinate dehydrogenase
HUT06_RS04895	COG4941	Belongs to the sigma-70 factor family
HUT06_RS04900	COG3795	YCII-related domain
HUT06_RS04960	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS04970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS04975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT06_RS04985	COG0183	Belongs to the thiolase family
HUT06_RS04990	COG0583	DNA-binding transcription factor activity
HUT06_RS05010	COG0124	histidyl-tRNA synthetase
HUT06_RS05050	COG1131	(ABC) transporter
HUT06_RS05060	COG0747	negative chemotaxis
HUT06_RS05065	COG0601	transmembrane transport
HUT06_RS05080	COG0488	(ABC) transporter
HUT06_RS05110	COG2409	Drug exporters of the RND superfamily
HUT06_RS05115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUT06_RS05120	COG4585	Histidine kinase
HUT06_RS05125	COG2197	response regulator
HUT06_RS05130	COG1136	(ABC) transporter
HUT06_RS05130	COG0577	efflux transmembrane transporter activity
HUT06_RS05180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT06_RS05180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT06_RS05185	COG2409	Drug exporters of the RND superfamily
HUT06_RS05190	COG4585	Histidine kinase
HUT06_RS05200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT06_RS05220	COG2018	Roadblock/LC7 domain
HUT06_RS05240	COG0587	DNA-directed DNA polymerase activity
HUT06_RS05255	COG3850	Histidine kinase
HUT06_RS05255	COG0642	Histidine kinase
HUT06_RS05265	COG0745	RESPONSE REGULATOR receiver
HUT06_RS05270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT06_RS05285	COG0745	RESPONSE REGULATOR receiver
HUT06_RS05290	COG0745	RESPONSE REGULATOR receiver
HUT06_RS05305	COG0714	Associated with various cellular activities
HUT06_RS05395	COG0475	glutathione-regulated potassium exporter activity
HUT06_RS05430	COG2207	Transcriptional regulator
HUT06_RS05440	COG1162	GTPase activity
HUT06_RS05475	COG2197	response regulator
HUT06_RS05480	COG4585	Histidine kinase
HUT06_RS05485	COG1131	(ABC) transporter
HUT06_RS05520	COG1131	(ABC) transporter
HUT06_RS05560	COG2197	response regulator
HUT06_RS05565	COG1902	pentaerythritol trinitrate reductase activity
HUT06_RS05575	COG2723	6-phospho-beta-galactosidase activity
HUT06_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS05610	COG1024	Enoyl-CoA hydratase
HUT06_RS05650	COG0456	acetyltransferase
HUT06_RS05655	COG0737	Belongs to the 5'-nucleotidase family
HUT06_RS05660	COG0306	phosphate transporter
HUT06_RS05675	COG0464	growth
HUT06_RS05690	COG0242	peptide deformylase activity
HUT06_RS05695	COG0745	RESPONSE REGULATOR receiver
HUT06_RS05700	COG2205	protein histidine kinase activity
HUT06_RS05705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT06_RS05715	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT06_RS05720	COG0745	RESPONSE REGULATOR receiver
HUT06_RS05785	COG1404	Belongs to the peptidase S8 family
HUT06_RS05795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT06_RS05830	COG1674	ftsk spoiiie
HUT06_RS05850	COG4842	Belongs to the WXG100 family
HUT06_RS05855	COG4842	Belongs to the WXG100 family
HUT06_RS05905	COG1316	TRANSCRIPTIONal
HUT06_RS05910	COG1216	Glycosyl transferase, family 2
HUT06_RS05920	COG1216	Glycosyl transferase, family 2
HUT06_RS05935	COG1216	Glycosyl transferase, family 2
HUT06_RS05960	COG3119	arylsulfatase activity
HUT06_RS06030	COG3442	glutamine amidotransferase
HUT06_RS06085	COG2318	DinB family
HUT06_RS06105	COG4044	May play a role in the intracellular transport of hydrophobic ligands
HUT06_RS06125	COG1490	D-aminoacyl-tRNA deacylase activity
HUT06_RS06130	COG3246	L-lysine catabolic process to acetate
HUT06_RS06145	COG2807	transmembrane transport
HUT06_RS06150	COG2186	Transcriptional regulator
HUT06_RS06185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT06_RS06190	COG1309	transcriptional regulator
HUT06_RS06195	COG2409	Drug exporters of the RND superfamily
HUT06_RS06205	COG1755	Isoprenylcysteine carboxyl methyltransferase
HUT06_RS06230	COG0667	Aldo Keto reductase
HUT06_RS06245	COG2130	NADP-dependent
HUT06_RS06270	COG3328	transposase activity
HUT06_RS06290	COG0778	Nitroreductase
HUT06_RS06295	COG5650	phosphatidylinositol metabolic process
HUT06_RS06305	COG2197	response regulator
HUT06_RS06330	COG0180	Tryptophanyl-tRNA synthetase
HUT06_RS06335	COG1309	transcriptional regulator
HUT06_RS06340	COG2226	methyltransferase
HUT06_RS06355	COG3384	dioxygenase
HUT06_RS06365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUT06_RS06400	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS06410	COG0588	phosphoglycerate mutase activity
HUT06_RS06430	COG1309	transcriptional regulator
HUT06_RS06450	COG0745	RESPONSE REGULATOR receiver
HUT06_RS06470	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT06_RS06475	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS06500	COG4941	Belongs to the sigma-70 factor family
HUT06_RS06505	COG0596	Alpha beta hydrolase
HUT06_RS06510	COG0215	cysteine-tRNA ligase activity
HUT06_RS06515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT06_RS06520	COG0697	spore germination
HUT06_RS06525	COG4941	Belongs to the sigma-70 factor family
HUT06_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS06565	COG1671	Belongs to the UPF0178 family
HUT06_RS06590	COG2205	protein histidine kinase activity
HUT06_RS06605	COG0477	Major facilitator Superfamily
HUT06_RS06620	COG2261	transglycosylase associated protein
HUT06_RS06635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT06_RS06670	COG1695	Transcriptional regulator
HUT06_RS06675	COG0515	serine threonine protein kinase
HUT06_RS06680	COG1595	DNA-templated transcription, initiation
HUT06_RS06690	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT06_RS06695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HUT06_RS06735	COG0459	protein refolding
HUT06_RS06780	COG1061	Type III restriction enzyme res subunit
HUT06_RS06785	COG0640	Transcriptional regulator
HUT06_RS06805	COG1309	transcriptional regulator
HUT06_RS06825	COG1278	Cold shock
HUT06_RS06830	COG2814	Major facilitator Superfamily
HUT06_RS06855	COG2814	Major facilitator Superfamily
HUT06_RS06860	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HUT06_RS06905	COG0259	pyridoxamine-phosphate oxidase activity
HUT06_RS06915	COG1573	uracil-dna glycosylase
HUT06_RS06935	COG2226	methyltransferase
HUT06_RS06955	COG0183	Belongs to the thiolase family
HUT06_RS06960	COG1024	Enoyl-CoA hydratase
HUT06_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS07000	COG0583	DNA-binding transcription factor activity
HUT06_RS07085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS07090	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT06_RS07090	COG1672	PFAM Archaeal ATPase
HUT06_RS07095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT06_RS07120	COG1725	Transcriptional regulator
HUT06_RS07150	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS07155	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS07175	COG0018	arginyl-trna synthetase
HUT06_RS07180	COG0416	fatty acid biosynthetic process
HUT06_RS07220	COG1881	PFAM PEBP family protein
HUT06_RS07225	COG0395	ABC-type sugar transport system, permease component
HUT06_RS07230	COG1175	transmembrane transport
HUT06_RS07235	COG3842	ATPase activity
HUT06_RS07245	COG1134	teichoic acid transport
HUT06_RS07245	COG1388	LysM domain
HUT06_RS07255	COG1597	lipid kinase activity
HUT06_RS07260	COG2720	vancomycin resistance protein
HUT06_RS07290	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS07295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT06_RS07320	COG0488	(ABC) transporter
HUT06_RS07330	COG0442	prolyl-tRNA aminoacylation
HUT06_RS07335	COG0442	prolyl-tRNA aminoacylation
HUT06_RS07365	COG1595	DNA-templated transcription, initiation
HUT06_RS07405	COG0612	Peptidase, M16
HUT06_RS07410	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT06_RS07445	COG1695	Transcriptional regulator
HUT06_RS07455	COG0464	growth
HUT06_RS07460	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUT06_RS07470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT06_RS07485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT06_RS07490	COG4941	Belongs to the sigma-70 factor family
HUT06_RS07495	COG3795	YCII-related domain
HUT06_RS07525	COG1136	(ABC) transporter
HUT06_RS07530	COG1136	(ABC) transporter
HUT06_RS07545	COG5564	TIM-barrel signal transduction protein
HUT06_RS07550	COG1917	Cupin 2, conserved barrel domain protein
HUT06_RS07555	COG3012	SEC-C Motif Domain Protein
HUT06_RS07570	COG4941	Belongs to the sigma-70 factor family
HUT06_RS07585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT06_RS07590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT06_RS07595	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT06_RS07650	COG3842	ATPase activity
HUT06_RS07670	COG2197	response regulator
HUT06_RS07675	COG0596	Alpha beta hydrolase
HUT06_RS07680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT06_RS07685	COG0549	Belongs to the carbamate kinase family
HUT06_RS07690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT06_RS07700	COG0531	amino acid
HUT06_RS07705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT06_RS07710	COG1595	DNA-templated transcription, initiation
HUT06_RS07715	COG2197	response regulator
HUT06_RS07750	COG1876	peptidase activity
HUT06_RS07765	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUT06_RS07770	COG2409	Drug exporters of the RND superfamily
HUT06_RS07780	COG3263	regulation of cellular component size
HUT06_RS07785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT06_RS07790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT06_RS07800	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT06_RS07805	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT06_RS07840	COG2205	protein histidine kinase activity
HUT06_RS07860	COG0745	RESPONSE REGULATOR receiver
HUT06_RS07865	COG1131	(ABC) transporter
HUT06_RS07900	COG1349	DNA-binding transcription factor activity
HUT06_RS07905	COG0215	cysteine-tRNA ligase activity
HUT06_RS07920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT06_RS07930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS07945	COG1335	isochorismatase
HUT06_RS07965	COG0701	Predicted permease
HUT06_RS08015	COG0222	ribosome binding
HUT06_RS08020	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS08025	COG0667	Aldo Keto reductase
HUT06_RS08035	COG0375	protein maturation
HUT06_RS08045	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HUT06_RS08080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT06_RS08090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT06_RS08130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS08165	COG3385	transposase activity
HUT06_RS08170	COG2255	four-way junction helicase activity
HUT06_RS08185	COG0457	Tetratricopeptide repeat
HUT06_RS08215	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS08290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS08300	COG0515	serine threonine protein kinase
HUT06_RS08300	COG2815	serine threonine protein kinase
HUT06_RS08315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT06_RS08340	COG0583	DNA-binding transcription factor activity
HUT06_RS08350	COG0477	Major facilitator Superfamily
HUT06_RS08355	COG2367	Beta-lactamase
HUT06_RS08360	COG0598	Magnesium transport protein CorA
HUT06_RS08410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT06_RS08415	COG0084	hydrolase, TatD family'
HUT06_RS08420	COG0741	lytic transglycosylase activity
HUT06_RS08425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT06_RS08435	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT06_RS08450	COG0488	(ABC) transporter
HUT06_RS08455	COG0154	amidase activity
HUT06_RS08460	COG1846	Transcriptional regulator
HUT06_RS08465	COG4106	trans-aconitate 2-methyltransferase activity
HUT06_RS08470	COG1309	transcriptional regulator
HUT06_RS08485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT06_RS08490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT06_RS08495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUT06_RS08500	COG0193	aminoacyl-tRNA hydrolase activity
HUT06_RS08510	COG1218	3'(2'),5'-bisphosphate nucleotidase
HUT06_RS08595	COG0730	response to heat
HUT06_RS08600	COG0529	Catalyzes the synthesis of activated sulfate
HUT06_RS08640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT06_RS08645	COG0604	alcohol dehydrogenase
HUT06_RS08645	COG3321	synthase
HUT06_RS08645	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS08660	COG5002	protein histidine kinase activity
HUT06_RS08680	COG0148	phosphopyruvate hydratase activity
HUT06_RS08710	COG1252	NADH dehydrogenase
HUT06_RS08730	COG0183	Belongs to the thiolase family
HUT06_RS08735	COG2755	lipolytic protein G-D-S-L family
HUT06_RS08745	COG2409	Drug exporters of the RND superfamily
HUT06_RS08770	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HUT06_RS08780	COG1940	carbohydrate kinase activity
HUT06_RS08785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT06_RS08795	COG0308	aminopeptidase N
HUT06_RS08800	COG1714	RDD family
HUT06_RS08810	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT06_RS08820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT06_RS08830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT06_RS08850	COG1234	tRNA 3'-trailer cleavage
HUT06_RS08855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT06_RS08860	COG1331	Highly conserved protein containing a thioredoxin domain
HUT06_RS08870	COG1309	transcriptional regulator
HUT06_RS08875	COG0477	Major facilitator Superfamily
HUT06_RS08885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT06_RS08890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT06_RS08900	COG0114	fumarate hydratase activity
HUT06_RS08910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT06_RS08910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT06_RS08925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT06_RS08970	COG1722	exodeoxyribonuclease VII activity
HUT06_RS08975	COG1570	exodeoxyribonuclease VII activity
HUT06_RS08990	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT06_RS09000	COG1322	Protein conserved in bacteria
HUT06_RS09005	COG0012	GTP binding
HUT06_RS09055	COG0494	nUDIX hydrolase
HUT06_RS09060	COG0791	NLP P60 protein
HUT06_RS09060	COG3883	PFAM NLP P60 protein
HUT06_RS09080	COG0542	response to heat
HUT06_RS09090	COG2815	serine threonine protein kinase
HUT06_RS09090	COG0515	serine threonine protein kinase
HUT06_RS09190	COG1316	TRANSCRIPTIONal
HUT06_RS09195	COG0515	serine threonine protein kinase
HUT06_RS09195	COG2815	serine threonine protein kinase
HUT06_RS09225	COG1053	succinate dehydrogenase
HUT06_RS09240	COG0583	DNA-binding transcription factor activity
HUT06_RS09245	COG0010	Belongs to the arginase family
HUT06_RS09250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT06_RS09255	COG1053	succinate dehydrogenase
HUT06_RS09270	COG1132	(ABC) transporter
HUT06_RS09275	COG1132	(ABC) transporter
HUT06_RS09290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT06_RS09310	COG1316	TRANSCRIPTIONal
HUT06_RS09315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT06_RS09325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT06_RS09345	COG1309	transcriptional regulator
HUT06_RS09355	COG2255	four-way junction helicase activity
HUT06_RS09375	COG2205	protein histidine kinase activity
HUT06_RS09380	COG0745	RESPONSE REGULATOR receiver
HUT06_RS09420	COG1136	(ABC) transporter
HUT06_RS09420	COG0577	efflux transmembrane transporter activity
HUT06_RS09485	COG0215	cysteine-tRNA ligase activity
HUT06_RS09490	COG2226	methyltransferase
HUT06_RS09500	COG1024	Enoyl-CoA hydratase
HUT06_RS09555	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUT06_RS09565	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS09570	COG0028	Belongs to the TPP enzyme family
HUT06_RS09580	COG1136	(ABC) transporter
HUT06_RS09590	COG2205	protein histidine kinase activity
HUT06_RS09595	COG0745	RESPONSE REGULATOR receiver
HUT06_RS09600	COG0326	Molecular chaperone. Has ATPase activity
HUT06_RS09610	COG4977	sequence-specific DNA binding
HUT06_RS09630	COG0640	Transcriptional regulator
HUT06_RS09635	COG0515	serine threonine protein kinase
HUT06_RS09640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUT06_RS09705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT06_RS09745	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS09750	COG4978	Transcriptional regulator
HUT06_RS09750	COG0789	Transcriptional regulator
HUT06_RS09760	COG2171	N-acyltransferase activity
HUT06_RS09780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT06_RS09785	COG1611	Belongs to the LOG family
HUT06_RS09840	COG4948	Mandelate Racemase Muconate Lactonizing
HUT06_RS09855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT06_RS09860	COG1309	transcriptional regulator
HUT06_RS09865	COG1131	(ABC) transporter
HUT06_RS09870	COG3559	Exporter of polyketide antibiotics
HUT06_RS09875	COG1611	Belongs to the LOG family
HUT06_RS09880	COG0028	Belongs to the TPP enzyme family
HUT06_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS09895	COG0673	inositol 2-dehydrogenase activity
HUT06_RS09915	COG1177	transmembrane transport
HUT06_RS09920	COG3842	ATPase activity
HUT06_RS09935	COG0561	phosphatase activity
HUT06_RS09945	COG1609	Transcriptional regulator
HUT06_RS09955	COG2188	Transcriptional regulator
HUT06_RS09960	COG1082	Xylose isomerase domain protein TIM barrel
HUT06_RS09965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT06_RS09975	COG3962	Belongs to the TPP enzyme family
HUT06_RS10005	COG2818	Glycosylase
HUT06_RS10015	COG0577	efflux transmembrane transporter activity
HUT06_RS10015	COG1136	(ABC) transporter
HUT06_RS10020	COG1024	Enoyl-CoA hydratase
HUT06_RS10030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT06_RS10045	COG1595	DNA-templated transcription, initiation
HUT06_RS10060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT06_RS10065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT06_RS10075	COG1846	Transcriptional regulator
HUT06_RS10085	COG2239	Acts as a magnesium transporter
HUT06_RS10120	COG0613	PHP domain protein
HUT06_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS10150	COG0277	FAD linked oxidase domain protein
HUT06_RS10170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT06_RS10180	COG0513	Belongs to the DEAD box helicase family
HUT06_RS10215	COG3285	dna ligase
HUT06_RS10215	COG1793	dna ligase
HUT06_RS10220	COG1793	dna ligase
HUT06_RS10220	COG3285	dna ligase
HUT06_RS10225	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT06_RS10235	COG2409	Drug exporters of the RND superfamily
HUT06_RS10240	COG2409	Drug exporters of the RND superfamily
HUT06_RS10250	COG1940	carbohydrate kinase activity
HUT06_RS10265	COG2201	protein-glutamate methylesterase activity
HUT06_RS10300	COG1404	Belongs to the peptidase S8 family
HUT06_RS10310	COG0210	DNA helicase
HUT06_RS10315	COG0210	DNA helicase
HUT06_RS10320	COG2226	methyltransferase
HUT06_RS10330	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS10345	COG0019	diaminopimelate decarboxylase activity
HUT06_RS10350	COG4264	IucA IucC family
HUT06_RS10360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT06_RS10375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT06_RS10395	COG1946	Acyl-CoA thioesterase
HUT06_RS10400	COG2197	response regulator
HUT06_RS10405	COG4585	Histidine kinase
HUT06_RS10410	COG0596	Alpha beta hydrolase
HUT06_RS10430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT06_RS10455	COG1418	mRNA catabolic process
HUT06_RS10485	COG1615	UPF0182 protein
HUT06_RS10500	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUT06_RS10510	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS10520	COG0506	proline dehydrogenase activity
HUT06_RS10525	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS10555	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS10560	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS10570	COG0300	oxidoreductase activity
HUT06_RS10580	COG1309	transcriptional regulator
HUT06_RS10590	COG0579	oxidoreductase
HUT06_RS10600	COG0483	inositol monophosphate 1-phosphatase activity
HUT06_RS10620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT06_RS10640	COG2135	peptidase activity
HUT06_RS10650	COG2226	methyltransferase
HUT06_RS10655	COG1595	DNA-templated transcription, initiation
HUT06_RS10660	COG5662	AntiSigma factor
HUT06_RS10665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT06_RS10670	COG2199	diguanylate cyclase activity
HUT06_RS10670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUT06_RS10735	COG3629	intracellular signal transduction
HUT06_RS10735	COG3903	Transcriptional regulator
HUT06_RS10740	COG0277	FAD linked oxidase domain protein
HUT06_RS10745	COG2205	protein histidine kinase activity
HUT06_RS10750	COG0745	RESPONSE REGULATOR receiver
HUT06_RS10770	COG0577	efflux transmembrane transporter activity
HUT06_RS10770	COG1136	(ABC) transporter
HUT06_RS10830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS10910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT06_RS10915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT06_RS10940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT06_RS10945	COG0439	Biotin carboxylase
HUT06_RS10970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT06_RS10975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUT06_RS10985	COG2188	Transcriptional regulator
HUT06_RS11005	COG1597	lipid kinase activity
HUT06_RS11020	COG2172	sigma factor antagonist activity
HUT06_RS11040	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS11055	COG2186	Transcriptional regulator
HUT06_RS11065	COG1175	transmembrane transport
HUT06_RS11070	COG3833	ABC-type maltose transport systems, permease component
HUT06_RS11080	COG4948	Mandelate Racemase Muconate Lactonizing
HUT06_RS11100	COG1131	(ABC) transporter
HUT06_RS11115	COG4585	Histidine kinase
HUT06_RS11120	COG2197	response regulator
HUT06_RS11160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT06_RS11165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT06_RS11170	COG0281	malic enzyme
HUT06_RS11175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS11180	COG0765	amino acid transport
HUT06_RS11185	COG1126	abc transporter atp-binding protein
HUT06_RS11215	COG0604	alcohol dehydrogenase
HUT06_RS11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT06_RS11235	COG0567	Dehydrogenase, E1 component
HUT06_RS11245	COG0435	Glutathione S-transferase
HUT06_RS11250	COG0586	Pfam SNARE associated Golgi protein
HUT06_RS11260	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS11265	COG1024	Enoyl-CoA hydratase
HUT06_RS11280	COG2018	Roadblock/LC7 domain
HUT06_RS11300	COG2018	Roadblock/LC7 domain
HUT06_RS11315	COG1846	Transcriptional regulator
HUT06_RS11315	COG1940	carbohydrate kinase activity
HUT06_RS11320	COG1129	ABC transporter
HUT06_RS11325	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS11330	COG4213	ABC transporter substrate-binding protein
HUT06_RS11335	COG0673	inositol 2-dehydrogenase activity
HUT06_RS11405	COG2226	methyltransferase
HUT06_RS11410	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS11415	COG2124	cytochrome p450
HUT06_RS11420	COG2124	cytochrome p450
HUT06_RS11425	COG0488	(ABC) transporter
HUT06_RS11440	COG0183	Belongs to the thiolase family
HUT06_RS11445	COG2124	cytochrome p450
HUT06_RS11460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT06_RS11465	COG0463	Glycosyl transferase, family 2
HUT06_RS11470	COG2124	cytochrome p450
HUT06_RS11475	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS11495	COG3835	regulator
HUT06_RS11505	COG2351	hydroxyisourate hydrolase activity
HUT06_RS11530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT06_RS11535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT06_RS11540	COG4266	Belongs to the allantoicase family
HUT06_RS11555	COG1309	transcriptional regulator
HUT06_RS11560	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS11565	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS11570	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS11575	COG0076	glutamate decarboxylase activity
HUT06_RS11580	COG1309	transcriptional regulator
HUT06_RS11585	COG0477	Major facilitator Superfamily
HUT06_RS11600	COG3572	ergothioneine biosynthetic process
HUT06_RS11605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT06_RS11615	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT06_RS11640	COG1609	Transcriptional regulator
HUT06_RS11645	COG2986	histidine ammonia-lyase
HUT06_RS11650	COG1125	glycine betaine transport
HUT06_RS11650	COG0517	IMP dehydrogenase activity
HUT06_RS11655	COG1174	glycine betaine transport
HUT06_RS11660	COG1174	glycine betaine transport
HUT06_RS11690	COG0596	Alpha beta hydrolase
HUT06_RS11715	COG2814	Major facilitator Superfamily
HUT06_RS11740	COG2986	histidine ammonia-lyase
HUT06_RS11745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT06_RS11755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT06_RS11795	COG1228	amidohydrolase
HUT06_RS11805	COG0616	signal peptide processing
HUT06_RS11825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT06_RS11835	COG2186	Transcriptional regulator
HUT06_RS11850	COG0366	Alpha amylase catalytic
HUT06_RS11855	COG0058	SHG alpha-glucan phosphorylase activity
HUT06_RS11865	COG1476	TRANSCRIPTIONal
HUT06_RS11880	COG4585	Histidine kinase
HUT06_RS11885	COG4279	zinc finger
HUT06_RS11890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT06_RS11900	COG1733	regulation of RNA biosynthetic process
HUT06_RS11910	COG4221	oxidoreductase activity
HUT06_RS11940	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT06_RS11975	COG0482	sulfurtransferase activity
HUT06_RS11990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT06_RS12010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT06_RS12015	COG0154	amidase activity
HUT06_RS12020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT06_RS12025	COG2133	pyrroloquinoline quinone binding
HUT06_RS12030	COG5001	Diguanylate cyclase
HUT06_RS12045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT06_RS12060	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUT06_RS12060	COG1136	(ABC) transporter
HUT06_RS12090	COG0473	3-isopropylmalate dehydrogenase activity
HUT06_RS12095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT06_RS12100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT06_RS12145	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS12180	COG2409	Drug exporters of the RND superfamily
HUT06_RS12195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS12205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT06_RS12215	COG0713	ATP synthesis coupled electron transport
HUT06_RS12230	COG1007	ATP synthesis coupled electron transport
HUT06_RS12240	COG1126	abc transporter atp-binding protein
HUT06_RS12245	COG0765	amino acid transport
HUT06_RS12255	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HUT06_RS12260	COG0583	DNA-binding transcription factor activity
HUT06_RS12265	COG2084	Dehydrogenase
HUT06_RS12275	COG0789	Transcriptional regulator
HUT06_RS12280	COG1414	Transcriptional regulator
HUT06_RS12285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT06_RS12290	COG0066	3-isopropylmalate dehydratase activity
HUT06_RS12300	COG0776	regulation of translation
HUT06_RS12310	COG1920	GTP binding
HUT06_RS12320	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT06_RS12325	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT06_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS12435	COG0351	phosphomethylpyrimidine kinase
HUT06_RS12440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT06_RS12445	COG1461	Dihydroxyacetone kinase
HUT06_RS12465	COG0742	ribosomal rna small subunit methyltransferase
HUT06_RS12475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT06_RS12485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT06_RS12490	COG0571	ribonuclease III activity
HUT06_RS12495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT06_RS12500	COG1254	Belongs to the acylphosphatase family
HUT06_RS12510	COG1196	nuclear chromosome segregation
HUT06_RS12520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT06_RS12545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT06_RS12555	COG0228	four-way junction DNA binding
HUT06_RS12560	COG1837	Belongs to the UPF0109 family
HUT06_RS12565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT06_RS12580	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT06_RS12585	COG0335	large ribosomal subunit rRNA binding
HUT06_RS12590	COG0681	Belongs to the peptidase S26 family
HUT06_RS12595	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT06_RS12615	COG0792	nuclease activity
HUT06_RS12620	COG4974	Belongs to the 'phage' integrase family
HUT06_RS12630	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT06_RS12635	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT06_RS12640	COG0528	UMP kinase activity
HUT06_RS12645	COG0233	cytoplasmic translational termination
HUT06_RS12650	COG0575	Belongs to the CDS family
HUT06_RS12660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT06_RS12700	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS12705	COG3842	ATPase activity
HUT06_RS12715	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT06_RS12720	COG1177	transmembrane transport
HUT06_RS12740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS12765	COG0515	serine threonine protein kinase
HUT06_RS12780	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT06_RS12790	COG0596	Alpha beta hydrolase
HUT06_RS12800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT06_RS12840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT06_RS12845	COG0596	Alpha beta hydrolase
HUT06_RS12850	COG0596	Alpha beta hydrolase
HUT06_RS12910	COG0477	Major facilitator Superfamily
HUT06_RS12920	COG0633	Ferredoxin
HUT06_RS12920	COG0543	2 iron, 2 sulfur cluster binding
HUT06_RS12925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT06_RS12940	COG2205	protein histidine kinase activity
HUT06_RS12950	COG2318	DinB family
HUT06_RS12960	COG0537	adenosine 5'-monophosphoramidase activity
HUT06_RS13000	COG1515	deoxyribonuclease V activity
HUT06_RS13010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT06_RS13010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT06_RS13025	COG1309	transcriptional regulator
HUT06_RS13075	COG4213	ABC transporter substrate-binding protein
HUT06_RS13085	COG4214	carbohydrate transport
HUT06_RS13095	COG1940	carbohydrate kinase activity
HUT06_RS13135	COG0779	Required for maturation of 30S ribosomal subunits
HUT06_RS13150	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT06_RS13160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT06_RS13165	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUT06_RS13170	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT06_RS13185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT06_RS13190	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT06_RS13195	COG0612	Peptidase, M16
HUT06_RS13200	COG1950	PFAM Membrane protein of
HUT06_RS13205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT06_RS13210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT06_RS13220	COG0456	acetyltransferase
HUT06_RS13235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT06_RS13250	COG0477	Major facilitator Superfamily
HUT06_RS13275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT06_RS13300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT06_RS13305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT06_RS13310	COG1674	ftsk spoiiie
HUT06_RS13320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT06_RS13335	COG1546	Belongs to the CinA family
HUT06_RS13335	COG1058	Belongs to the CinA family
HUT06_RS13340	COG1396	sequence-specific DNA binding
HUT06_RS13355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT06_RS13370	COG0395	ABC-type sugar transport system, permease component
HUT06_RS13375	COG1175	transmembrane transport
HUT06_RS13390	COG0653	protein targeting
HUT06_RS13395	COG1201	RNA secondary structure unwinding
HUT06_RS13415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT06_RS13420	COG2137	regulation of response to DNA damage stimulus
HUT06_RS13425	COG1418	mRNA catabolic process
HUT06_RS13430	COG1073	alpha beta
HUT06_RS13435	COG0765	amino acid transport
HUT06_RS13440	COG0765	amino acid transport
HUT06_RS13445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS13450	COG1126	abc transporter atp-binding protein
HUT06_RS13455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT06_RS13470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT06_RS13475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUT06_RS13510	COG0247	lactate metabolic process
HUT06_RS13515	COG0277	FAD linked oxidase domain protein
HUT06_RS13520	COG0277	FAD linked oxidase domain protein
HUT06_RS13530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT06_RS13535	COG1228	amidohydrolase
HUT06_RS13540	COG1307	EDD domain protein, DegV family
HUT06_RS13575	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUT06_RS13580	COG0268	Binds directly to 16S ribosomal RNA
HUT06_RS13585	COG0481	GTPase activity
HUT06_RS13620	COG1420	regulation of RNA biosynthetic process
HUT06_RS13625	COG0484	heat shock protein binding
HUT06_RS13645	COG0537	adenosine 5'-monophosphoramidase activity
HUT06_RS13655	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT06_RS13670	COG2409	Drug exporters of the RND superfamily
HUT06_RS13675	COG3903	Transcriptional regulator
HUT06_RS13675	COG3629	intracellular signal transduction
HUT06_RS13680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT06_RS13695	COG1834	amidinotransferase
HUT06_RS13700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT06_RS13715	COG1381	Involved in DNA repair and RecF pathway recombination
HUT06_RS13720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT06_RS13725	COG1764	response to oxidative stress
HUT06_RS13740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT06_RS13745	COG1121	(ABC) transporter
HUT06_RS13750	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUT06_RS13770	COG0423	glycine-tRNA ligase activity
HUT06_RS13785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT06_RS13785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT06_RS13800	COG3387	PFAM Glycoside hydrolase 15-related
HUT06_RS13805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT06_RS13805	COG0574	Belongs to the PEP-utilizing enzyme family
HUT06_RS13815	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT06_RS13820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT06_RS13825	COG2223	nitrite transmembrane transporter activity
HUT06_RS13835	COG1595	DNA-templated transcription, initiation
HUT06_RS13840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS13845	COG0789	Transcriptional regulator
HUT06_RS13870	COG0358	DNA primase activity
HUT06_RS13875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT06_RS13880	COG0393	Putative heavy-metal-binding
HUT06_RS13890	COG2837	iron assimilation
HUT06_RS13930	COG1358	cellular component organization or biogenesis
HUT06_RS13980	COG0270	DNA (cytosine-5-)-methyltransferase activity
HUT06_RS14050	COG2188	Transcriptional regulator
HUT06_RS14060	COG0305	Participates in initiation and elongation during chromosome replication
HUT06_RS14075	COG3629	intracellular signal transduction
HUT06_RS14095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT06_RS14095	COG2111	Na H antiporter
HUT06_RS14120	COG1320	monovalent cation:proton antiporter activity
HUT06_RS14130	COG4585	Histidine kinase
HUT06_RS14135	COG2197	response regulator
HUT06_RS14160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS14165	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS14170	COG1120	ATPase activity
HUT06_RS14195	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS14245	COG0477	Major facilitator Superfamily
HUT06_RS14265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT06_RS14285	COG0531	amino acid
HUT06_RS14290	COG0405	Gamma-glutamyltransferase
HUT06_RS14305	COG0477	Major facilitator Superfamily
HUT06_RS14315	COG1937	Protein conserved in bacteria
HUT06_RS14320	COG0588	phosphoglycerate mutase activity
HUT06_RS14335	COG1929	Belongs to the glycerate kinase type-1 family
HUT06_RS14340	COG2252	PERMEase
HUT06_RS14345	COG3835	regulator
HUT06_RS14365	COG3336	cytochrome c oxidase
HUT06_RS14370	COG4585	Histidine kinase
HUT06_RS14375	COG2197	response regulator
HUT06_RS14395	COG0745	RESPONSE REGULATOR receiver
HUT06_RS14400	COG2205	protein histidine kinase activity
HUT06_RS14445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUT06_RS14445	COG0475	glutathione-regulated potassium exporter activity
HUT06_RS14460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT06_RS14465	COG0477	Major facilitator Superfamily
HUT06_RS14490	COG1674	ftsk spoiiie
HUT06_RS14550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT06_RS14550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT06_RS14570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS14575	COG0765	amino acid transport
HUT06_RS14580	COG1126	abc transporter atp-binding protein
HUT06_RS14585	COG0174	glutamine synthetase
HUT06_RS14590	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT06_RS14605	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT06_RS14615	COG2267	carboxylic ester hydrolase activity
HUT06_RS14655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT06_RS14665	COG0321	lipoyl(octanoyl) transferase activity
HUT06_RS14670	COG3340	Belongs to the peptidase S51 family
HUT06_RS14675	COG1090	epimerase
HUT06_RS14685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT06_RS14690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT06_RS14695	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUT06_RS14715	COG0667	Aldo Keto reductase
HUT06_RS14735	COG0501	Belongs to the peptidase M48B family
HUT06_RS14745	COG0501	Belongs to the peptidase M48B family
HUT06_RS14755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT06_RS14765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT06_RS14775	COG1104	cysteine desulfurase activity
HUT06_RS14780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT06_RS14785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT06_RS14795	COG1376	ErfK ybiS ycfS ynhG family protein
HUT06_RS14800	COG0501	Belongs to the peptidase M48B family
HUT06_RS14815	COG0791	NLP P60 protein
HUT06_RS14840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUT06_RS14850	COG1845	cytochrome c oxidase, subunit III
HUT06_RS14855	COG2010	Cytochrome c
HUT06_RS14860	COG0723	plastoquinol--plastocyanin reductase activity
HUT06_RS14865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT06_RS14870	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS14915	COG1022	Amp-dependent synthetase and ligase
HUT06_RS14920	COG3142	Participates in the control of copper homeostasis
HUT06_RS14935	COG1940	carbohydrate kinase activity
HUT06_RS14960	COG2197	response regulator
HUT06_RS14970	COG3220	belongs to the UPF0276 family
HUT06_RS14975	COG3220	belongs to the UPF0276 family
HUT06_RS14985	COG0301	tRNA thio-modification
HUT06_RS14995	COG0697	spore germination
HUT06_RS15000	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HUT06_RS15005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT06_RS15010	COG3275	phosphorelay sensor kinase activity
HUT06_RS15025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT06_RS15030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUT06_RS15035	COG2815	serine threonine protein kinase
HUT06_RS15035	COG0515	serine threonine protein kinase
HUT06_RS15040	COG0697	spore germination
HUT06_RS15045	COG2022	thiamine diphosphate biosynthetic process
HUT06_RS15055	COG2022	thiamine diphosphate biosynthetic process
HUT06_RS15055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT06_RS15070	COG0352	thiamine-phosphate diphosphorylase activity
HUT06_RS15085	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT06_RS15140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS15170	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUT06_RS15175	COG0540	Belongs to the ATCase OTCase family
HUT06_RS15180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT06_RS15185	COG0505	Belongs to the CarA family
HUT06_RS15195	COG0543	2 iron, 2 sulfur cluster binding
HUT06_RS15200	COG0167	dihydroorotate dehydrogenase activity
HUT06_RS15205	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT06_RS15215	COG0194	GDP metabolic process
HUT06_RS15220	COG1758	RNA polymerase activity
HUT06_RS15230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT06_RS15240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUT06_RS15250	COG0242	peptide deformylase activity
HUT06_RS15255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT06_RS15265	COG0671	phosphoesterase, PA-phosphatase related
HUT06_RS15270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUT06_RS15275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT06_RS15350	COG3201	nicotinamide mononucleotide transporter
HUT06_RS15355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT06_RS15355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT06_RS15360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT06_RS15365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT06_RS15405	COG3608	succinylglutamate desuccinylase aspartoacylase
HUT06_RS15405	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUT06_RS15410	COG0746	molybdenum cofactor guanylyltransferase activity
HUT06_RS15435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUT06_RS15440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUT06_RS15450	COG2508	Transcriptional regulator
HUT06_RS15455	COG2233	PERMEase
HUT06_RS15510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT06_RS15515	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HUT06_RS15535	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS15540	COG1309	transcriptional regulator
HUT06_RS15550	COG1131	(ABC) transporter
HUT06_RS15560	COG4585	Histidine kinase
HUT06_RS15565	COG2197	response regulator
HUT06_RS15605	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS15655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT06_RS15660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT06_RS15665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT06_RS15670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT06_RS15675	COG1309	transcriptional regulator
HUT06_RS15685	COG1024	Enoyl-CoA hydratase
HUT06_RS15690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS15700	COG0006	proline dipeptidase activity
HUT06_RS15705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT06_RS15710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT06_RS15720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT06_RS15740	COG0714	Associated with various cellular activities
HUT06_RS15745	COG2001	Belongs to the MraZ family
HUT06_RS15750	COG0275	rRNA processing
HUT06_RS15760	COG0768	penicillin binding
HUT06_RS15765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT06_RS15770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUT06_RS15775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT06_RS15780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT06_RS15790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT06_RS15795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT06_RS15805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUT06_RS15820	COG1799	cell septum assembly
HUT06_RS15830	COG3599	regulation of cell shape
HUT06_RS15845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT06_RS15855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT06_RS15880	COG0587	DNA-directed DNA polymerase activity
HUT06_RS15905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUT06_RS15910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT06_RS15915	COG0384	phenazine biosynthesis protein PhzF
HUT06_RS15920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT06_RS15925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT06_RS15930	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT06_RS15940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT06_RS15945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT06_RS15950	COG0107	imidazoleglycerol-phosphate synthase activity
HUT06_RS15960	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS15965	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS16000	COG1132	(ABC) transporter
HUT06_RS16005	COG1132	(ABC) transporter
HUT06_RS16015	COG1278	Cold shock
HUT06_RS16020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUT06_RS16030	COG0745	RESPONSE REGULATOR receiver
HUT06_RS16040	COG0134	indole-3-glycerol-phosphate synthase activity
HUT06_RS16045	COG0133	tryptophan synthase activity
HUT06_RS16050	COG0159	tryptophan synthase activity
HUT06_RS16070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT06_RS16090	COG0067	glutamate synthase
HUT06_RS16090	COG0070	glutamate synthase
HUT06_RS16090	COG0069	glutamate synthase activity
HUT06_RS16125	COG0693	protein deglycase activity
HUT06_RS16175	COG2050	protein possibly involved in aromatic compounds catabolism
HUT06_RS16205	COG0237	dephospho-CoA kinase activity
HUT06_RS16225	COG5635	Nacht domain
HUT06_RS16225	COG2319	Wd-40 repeat
HUT06_RS16250	COG4585	Histidine kinase
HUT06_RS16255	COG0556	nucleotide-excision repair
HUT06_RS16290	COG2197	response regulator
HUT06_RS16295	COG4585	Histidine kinase
HUT06_RS16335	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS16355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT06_RS16375	COG2070	2-Nitropropane dioxygenase
HUT06_RS16390	COG1126	abc transporter atp-binding protein
HUT06_RS16395	COG0765	amino acid transport
HUT06_RS16400	COG0765	amino acid transport
HUT06_RS16410	COG5285	phytanoyl-CoA dioxygenase
HUT06_RS16415	COG1917	Cupin 2, conserved barrel domain protein
HUT06_RS16420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT06_RS16425	COG0456	acetyltransferase
HUT06_RS16440	COG0504	CTP synthase activity
HUT06_RS16465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUT06_RS16470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT06_RS16480	COG4401	Chorismate mutase type I
HUT06_RS16490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUT06_RS16495	COG1160	GTP binding
HUT06_RS16535	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT06_RS16560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT06_RS16575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT06_RS16585	COG0542	response to heat
HUT06_RS16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT06_RS16680	COG0248	Ppx GppA phosphatase
HUT06_RS16685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT06_RS16690	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT06_RS16700	COG0477	Major facilitator Superfamily
HUT06_RS16715	COG1357	PFAM Pentapeptide repeats (8 copies)
HUT06_RS16720	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT06_RS16745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT06_RS16750	COG0583	DNA-binding transcription factor activity
HUT06_RS16760	COG2205	protein histidine kinase activity
HUT06_RS16765	COG0745	RESPONSE REGULATOR receiver
HUT06_RS16785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT06_RS16810	COG0586	Pfam SNARE associated Golgi protein
HUT06_RS16815	COG4585	Histidine kinase
HUT06_RS16820	COG2201	protein-glutamate methylesterase activity
HUT06_RS16825	COG1063	alcohol dehydrogenase
HUT06_RS16870	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT06_RS16890	COG0477	Major facilitator Superfamily
HUT06_RS16950	COG1595	DNA-templated transcription, initiation
HUT06_RS16960	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS16975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT06_RS16995	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS17010	COG1120	ATPase activity
HUT06_RS17015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS17025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS17045	COG0477	Major facilitator Superfamily
HUT06_RS17090	COG0776	regulation of translation
HUT06_RS17095	COG0427	acetyl-CoA hydrolase
HUT06_RS17130	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS17170	COG0010	Belongs to the arginase family
HUT06_RS17175	COG0477	Major facilitator Superfamily
HUT06_RS17195	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS17235	COG1024	Enoyl-CoA hydratase
HUT06_RS17245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT06_RS17265	COG0745	RESPONSE REGULATOR receiver
HUT06_RS17275	COG1937	Protein conserved in bacteria
HUT06_RS17285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUT06_RS17290	COG0730	response to heat
HUT06_RS17310	COG1177	transmembrane transport
HUT06_RS17315	COG3842	ATPase activity
HUT06_RS17335	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS17375	COG0798	PFAM Bile acid sodium symporter
HUT06_RS17380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT06_RS17390	COG2072	flavoprotein involved in K transport
HUT06_RS17395	COG0640	Transcriptional regulator
HUT06_RS17425	COG2208	phosphoserine phosphatase activity
HUT06_RS17450	COG0596	Alpha beta hydrolase
HUT06_RS17480	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS17490	COG1141	Ferredoxin
HUT06_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS17505	COG3321	synthase
HUT06_RS17505	COG0300	oxidoreductase activity
HUT06_RS17505	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS17505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT06_RS17520	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT06_RS17530	COG2124	cytochrome p450
HUT06_RS17535	COG0475	glutathione-regulated potassium exporter activity
HUT06_RS17550	COG3903	Transcriptional regulator
HUT06_RS17550	COG3629	intracellular signal transduction
HUT06_RS17560	COG2124	cytochrome p450
HUT06_RS17570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT06_RS17575	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS17595	COG2197	response regulator
HUT06_RS17605	COG1131	(ABC) transporter
HUT06_RS17630	COG4257	antibiotic catabolic process
HUT06_RS17635	COG0110	maltose O-acetyltransferase activity
HUT06_RS17640	COG0583	DNA-binding transcription factor activity
HUT06_RS17660	COG0596	Alpha beta hydrolase
HUT06_RS17700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS17705	COG1414	Transcriptional regulator
HUT06_RS17715	COG0477	Major facilitator Superfamily
HUT06_RS17720	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS17730	COG0583	DNA-binding transcription factor activity
HUT06_RS17810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT06_RS17815	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS17820	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS17825	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS17830	COG1309	transcriptional regulator
HUT06_RS17835	COG0183	Belongs to the thiolase family
HUT06_RS17840	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HUT06_RS17845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT06_RS17850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT06_RS17860	COG1414	Transcriptional regulator
HUT06_RS17865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT06_RS17875	COG1802	Transcriptional regulator
HUT06_RS17880	COG1024	Enoyl-CoA hydratase
HUT06_RS17885	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS17895	COG0667	Aldo Keto reductase
HUT06_RS17920	COG1024	Enoyl-CoA hydratase
HUT06_RS17925	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS17930	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS17935	COG0515	serine threonine protein kinase
HUT06_RS17940	COG1643	Atp-dependent helicase
HUT06_RS17975	COG1119	ATPase activity
HUT06_RS18025	COG2050	protein possibly involved in aromatic compounds catabolism
HUT06_RS18050	COG1131	(ABC) transporter
HUT06_RS18055	COG4585	Histidine kinase
HUT06_RS18060	COG2197	response regulator
HUT06_RS18195	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS18210	COG1129	ABC transporter
HUT06_RS18215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS18230	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS18255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT06_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS18280	COG0494	nUDIX hydrolase
HUT06_RS18295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT06_RS18305	COG2205	protein histidine kinase activity
HUT06_RS18305	COG3437	response regulator, receiver
HUT06_RS18305	COG3850	Histidine kinase
HUT06_RS18305	COG4999	Histidine kinase
HUT06_RS18325	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT06_RS18335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT06_RS18405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUT06_RS18410	COG2124	cytochrome p450
HUT06_RS18420	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS18425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS18430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT06_RS18440	COG2124	cytochrome p450
HUT06_RS18480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT06_RS18485	COG4166	transmembrane transport
HUT06_RS18490	COG0601	transmembrane transport
HUT06_RS18495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT06_RS18500	COG0444	Belongs to the ABC transporter superfamily
HUT06_RS18505	COG4608	Belongs to the ABC transporter superfamily
HUT06_RS18515	COG0702	epimerase
HUT06_RS18545	COG2172	sigma factor antagonist activity
HUT06_RS18550	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT06_RS18555	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT06_RS18580	COG2366	antibiotic biosynthetic process
HUT06_RS18590	COG0488	(ABC) transporter
HUT06_RS18620	COG0789	Transcriptional regulator
HUT06_RS18630	COG1733	regulation of RNA biosynthetic process
HUT06_RS18645	COG2271	Major facilitator Superfamily
HUT06_RS18710	COG0583	DNA-binding transcription factor activity
HUT06_RS18715	COG1132	(ABC) transporter
HUT06_RS18740	COG3971	2-oxopent-4-enoate hydratase activity
HUT06_RS18755	COG1917	Cupin 2, conserved barrel domain protein
HUT06_RS18765	COG3844	kynureninase activity
HUT06_RS18770	COG1278	Cold shock
HUT06_RS18775	COG0738	Major facilitator superfamily
HUT06_RS18805	COG2197	response regulator
HUT06_RS18810	COG4585	Histidine kinase
HUT06_RS18815	COG2226	methyltransferase
HUT06_RS18820	COG0477	Major facilitator Superfamily
HUT06_RS18825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT06_RS18865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUT06_RS18870	COG1560	Kdo2-lipid A biosynthetic process
HUT06_RS18875	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS18890	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT06_RS18900	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT06_RS18905	COG0217	transcriptional regulatory protein
HUT06_RS18910	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUT06_RS18915	COG0632	four-way junction helicase activity
HUT06_RS18920	COG2255	four-way junction helicase activity
HUT06_RS18925	COG1862	Preprotein translocase
HUT06_RS18930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT06_RS18935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT06_RS18940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT06_RS18945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT06_RS18950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT06_RS18955	COG0124	histidyl-tRNA synthetase
HUT06_RS18965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT06_RS18970	COG1196	nuclear chromosome segregation
HUT06_RS19010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT06_RS19015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUT06_RS19025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT06_RS19060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT06_RS19065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT06_RS19075	COG5002	protein histidine kinase activity
HUT06_RS19080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT06_RS19085	COG0072	phenylalanine-tRNA ligase activity
HUT06_RS19085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT06_RS19100	COG4555	ABC transporter
HUT06_RS19105	COG1672	PFAM Archaeal ATPase
HUT06_RS19105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT06_RS19110	COG0488	(ABC) transporter
HUT06_RS19135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT06_RS19140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT06_RS19145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT06_RS19150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT06_RS19155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT06_RS19160	COG1438	arginine binding
HUT06_RS19165	COG0137	argininosuccinate synthase activity
HUT06_RS19170	COG0165	Argininosuccinate lyase
HUT06_RS19175	COG2094	Belongs to the DNA glycosylase MPG family
HUT06_RS19180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT06_RS19220	COG1309	transcriptional regulator
HUT06_RS19230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT06_RS19260	COG1316	TRANSCRIPTIONal
HUT06_RS19270	COG1522	sequence-specific DNA binding
HUT06_RS19285	COG0477	Major facilitator Superfamily
HUT06_RS19320	COG0436	Aminotransferase
HUT06_RS19335	COG1376	ErfK ybiS ycfS ynhG family protein
HUT06_RS19340	COG1376	ErfK ybiS ycfS ynhG family protein
HUT06_RS19360	COG2205	protein histidine kinase activity
HUT06_RS19365	COG0745	RESPONSE REGULATOR receiver
HUT06_RS19380	COG1136	(ABC) transporter
HUT06_RS19380	COG0577	efflux transmembrane transporter activity
HUT06_RS19385	COG0577	efflux transmembrane transporter activity
HUT06_RS19390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS19400	COG1070	Carbohydrate kinase
HUT06_RS19435	COG0395	ABC-type sugar transport system, permease component
HUT06_RS19445	COG5297	Belongs to the glycosyl hydrolase family 6
HUT06_RS19460	COG4733	cellulase activity
HUT06_RS19460	COG5297	Belongs to the glycosyl hydrolase family 6
HUT06_RS19465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT06_RS19485	COG2197	response regulator
HUT06_RS19560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS19565	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS19570	COG1120	ATPase activity
HUT06_RS19580	COG0477	Major facilitator Superfamily
HUT06_RS19585	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT06_RS19590	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT06_RS19640	COG1169	isochorismate synthase
HUT06_RS19655	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT06_RS19670	COG2814	Major facilitator Superfamily
HUT06_RS19690	COG1309	transcriptional regulator
HUT06_RS19720	COG1349	DNA-binding transcription factor activity
HUT06_RS19725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT06_RS19730	COG1063	alcohol dehydrogenase
HUT06_RS19735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT06_RS19735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT06_RS19740	COG2213	PTS system mannitol-specific
HUT06_RS19750	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT06_RS19760	COG0697	spore germination
HUT06_RS19795	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT06_RS19810	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS19850	COG0673	inositol 2-dehydrogenase activity
HUT06_RS19880	COG2076	Multidrug Resistance protein
HUT06_RS19895	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS19925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT06_RS19935	COG3290	protein histidine kinase activity
HUT06_RS19940	COG4565	transcriptional regulatory protein
HUT06_RS19945	COG4555	ABC transporter
HUT06_RS19975	COG1215	transferase activity, transferring glycosyl groups
HUT06_RS19980	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS19985	COG1309	transcriptional regulator
HUT06_RS20020	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS20030	COG2378	regulation of single-species biofilm formation
HUT06_RS20035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT06_RS20055	COG2050	protein possibly involved in aromatic compounds catabolism
HUT06_RS20070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT06_RS20100	COG1690	Belongs to the RtcB family
HUT06_RS20110	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUT06_RS20120	COG0300	oxidoreductase activity
HUT06_RS20125	COG3973	AAA domain
HUT06_RS20140	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS20145	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS20150	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUT06_RS20155	COG0563	adenylate kinase activity
HUT06_RS20165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUT06_RS20165	COG3608	succinylglutamate desuccinylase aspartoacylase
HUT06_RS20180	COG3485	protocatechuate 3,4-dioxygenase
HUT06_RS20185	COG3485	protocatechuate 3,4-dioxygenase
HUT06_RS20190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT06_RS20200	COG1414	Transcriptional regulator
HUT06_RS20210	COG2409	Drug exporters of the RND superfamily
HUT06_RS20220	COG0189	ligase activity
HUT06_RS20220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUT06_RS20235	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT06_RS20250	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HUT06_RS20265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT06_RS20285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT06_RS20290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT06_RS20315	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS20320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUT06_RS20320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUT06_RS20325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT06_RS20330	COG0297	glycogen (starch) synthase activity
HUT06_RS20340	COG0859	PFAM glycosyl transferase family 9
HUT06_RS20345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUT06_RS20350	COG2192	nodulation
HUT06_RS20365	COG0477	Major facilitator Superfamily
HUT06_RS20380	COG1881	PFAM PEBP family protein
HUT06_RS20385	COG0667	Aldo Keto reductase
HUT06_RS20390	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS20395	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS20395	COG2030	dehydratase
HUT06_RS20400	COG0583	DNA-binding transcription factor activity
HUT06_RS20405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT06_RS20415	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS20420	COG0022	dehydrogenase e1 component
HUT06_RS20485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT06_RS20500	COG2188	Transcriptional regulator
HUT06_RS20520	COG0702	epimerase
HUT06_RS20545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT06_RS20550	COG4585	Histidine kinase
HUT06_RS20560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT06_RS20565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT06_RS20570	COG1280	lysine exporter protein (LysE YggA)
HUT06_RS20615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT06_RS20615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT06_RS20640	COG0247	lactate metabolic process
HUT06_RS20645	COG1139	Iron-sulfur cluster binding protein
HUT06_RS20650	COG1556	Lactate utilization protein
HUT06_RS20670	COG2223	nitrite transmembrane transporter activity
HUT06_RS20685	COG0243	molybdopterin cofactor binding
HUT06_RS20725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT06_RS20745	COG4948	Mandelate Racemase Muconate Lactonizing
HUT06_RS20750	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HUT06_RS20775	COG0475	glutathione-regulated potassium exporter activity
HUT06_RS20785	COG1169	isochorismate synthase
HUT06_RS20835	COG1733	regulation of RNA biosynthetic process
HUT06_RS20840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUT06_RS20855	COG1649	PFAM Uncharacterised BCR, COG1649
HUT06_RS20925	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT06_RS20945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT06_RS20975	COG0477	Major facilitator Superfamily
HUT06_RS20980	COG2197	response regulator
HUT06_RS20985	COG4585	Histidine kinase
HUT06_RS20990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT06_RS21010	COG2608	mercury ion transmembrane transporter activity
HUT06_RS21025	COG3634	alkyl hydroperoxide reductase activity
HUT06_RS21030	COG2814	Major facilitator Superfamily
HUT06_RS21065	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT06_RS21075	COG4608	Belongs to the ABC transporter superfamily
HUT06_RS21115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT06_RS21145	COG4974	Belongs to the 'phage' integrase family
HUT06_RS21205	COG1715	Restriction endonuclease
HUT06_RS21325	COG0419	ATPase involved in DNA repair
HUT06_RS21335	COG0477	Major facilitator Superfamily
HUT06_RS21395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT06_RS21455	COG3547	Transposase (IS116 IS110 IS902 family)
HUT06_RS21590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT06_RS21630	COG1595	DNA-templated transcription, initiation
HUT06_RS21650	COG4977	sequence-specific DNA binding
HUT06_RS21705	COG1846	Transcriptional regulator
HUT06_RS21710	COG2378	regulation of single-species biofilm formation
HUT06_RS21725	COG2111	Na H antiporter
HUT06_RS21725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT06_RS21760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS21810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT06_RS21820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HUT06_RS21825	COG1132	(ABC) transporter
HUT06_RS21835	COG4988	ABC transporter
HUT06_RS21845	COG1271	oxidase subunit
HUT06_RS21920	COG2197	response regulator
HUT06_RS21930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT06_RS21950	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT06_RS21960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT06_RS21975	COG3795	YCII-related domain
HUT06_RS21990	COG1739	Uncharacterized protein family UPF0029
HUT06_RS22035	COG0583	DNA-binding transcription factor activity
HUT06_RS22055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT06_RS22085	COG0583	DNA-binding transcription factor activity
HUT06_RS22100	COG3467	pyridoxamine 5'-phosphate
HUT06_RS22120	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS22130	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT06_RS22135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT06_RS22135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT06_RS22140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT06_RS22150	COG2205	protein histidine kinase activity
HUT06_RS22155	COG0745	RESPONSE REGULATOR receiver
HUT06_RS22165	COG1162	GTPase activity
HUT06_RS22185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT06_RS22215	COG0714	Associated with various cellular activities
HUT06_RS22225	COG2304	oxidoreductase activity
HUT06_RS22230	COG2813	Specifically methylates the guanine in position
HUT06_RS22235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT06_RS22240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUT06_RS22255	COG2813	Specifically methylates the guanine in position
HUT06_RS22285	COG0740	serine-type endopeptidase activity
HUT06_RS22290	COG0740	serine-type endopeptidase activity
HUT06_RS22300	COG2197	response regulator
HUT06_RS22315	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUT06_RS22320	COG1216	Glycosyl transferase, family 2
HUT06_RS22330	COG1607	acyl-coa hydrolase
HUT06_RS22335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT06_RS22340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUT06_RS22370	COG0604	alcohol dehydrogenase
HUT06_RS22375	COG1509	lysine 2,3-aminomutase activity
HUT06_RS22380	COG2124	cytochrome p450
HUT06_RS22390	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS22400	COG1940	carbohydrate kinase activity
HUT06_RS22410	COG1175	transmembrane transport
HUT06_RS22415	COG0395	ABC-type sugar transport system, permease component
HUT06_RS22420	COG1486	melibiose metabolic process
HUT06_RS22435	COG1522	sequence-specific DNA binding
HUT06_RS22440	COG1609	Transcriptional regulator
HUT06_RS22450	COG0395	ABC-type sugar transport system, permease component
HUT06_RS22455	COG1175	transmembrane transport
HUT06_RS22460	COG1653	transport
HUT06_RS22475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUT06_RS22490	COG5398	heme oxygenase
HUT06_RS22515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT06_RS22520	COG2146	nitrite reductase [NAD(P)H] activity
HUT06_RS22520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT06_RS22540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT06_RS22555	COG0247	lactate metabolic process
HUT06_RS22555	COG0277	FAD linked oxidase domain protein
HUT06_RS22560	COG3387	PFAM Glycoside hydrolase 15-related
HUT06_RS22570	COG0577	efflux transmembrane transporter activity
HUT06_RS22570	COG1136	(ABC) transporter
HUT06_RS22585	COG1131	(ABC) transporter
HUT06_RS22600	COG0805	protein transport
HUT06_RS22605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT06_RS22645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT06_RS22650	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT06_RS22655	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT06_RS22675	COG4122	O-methyltransferase activity
HUT06_RS22680	COG1222	aaa ATPase
HUT06_RS22690	COG1994	Peptidase M50
HUT06_RS22690	COG0517	IMP dehydrogenase activity
HUT06_RS22700	COG4585	Histidine kinase
HUT06_RS22705	COG2197	response regulator
HUT06_RS22710	COG0577	efflux transmembrane transporter activity
HUT06_RS22710	COG1136	(ABC) transporter
HUT06_RS22715	COG1136	(ABC) transporter
HUT06_RS22715	COG0577	efflux transmembrane transporter activity
HUT06_RS22725	COG0444	Belongs to the ABC transporter superfamily
HUT06_RS22735	COG0747	negative chemotaxis
HUT06_RS22740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT06_RS22750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT06_RS22765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUT06_RS22770	COG0515	serine threonine protein kinase
HUT06_RS22770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT06_RS22775	COG0215	cysteine-tRNA ligase activity
HUT06_RS22785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT06_RS22815	COG0598	Magnesium transport protein CorA
HUT06_RS22825	COG0667	Aldo Keto reductase
HUT06_RS22830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT06_RS22845	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS22860	COG3360	Dodecin
HUT06_RS22895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT06_RS22895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT06_RS22895	COG1703	isobutyryl-CoA mutase activity
HUT06_RS22915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS22920	COG0477	Major facilitator Superfamily
HUT06_RS22940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT06_RS22945	COG2267	carboxylic ester hydrolase activity
HUT06_RS22955	COG1690	Belongs to the RtcB family
HUT06_RS22980	COG0709	Synthesizes selenophosphate from selenide and ATP
HUT06_RS23005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT06_RS23025	COG0517	IMP dehydrogenase activity
HUT06_RS23025	COG0516	GMP reductase activity
HUT06_RS23030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT06_RS23035	COG2364	Membrane
HUT06_RS23040	COG1929	Belongs to the glycerate kinase type-1 family
HUT06_RS23050	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT06_RS23055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT06_RS23065	COG1132	(ABC) transporter
HUT06_RS23070	COG2936	dipeptidyl-peptidase activity
HUT06_RS23085	COG0488	(ABC) transporter
HUT06_RS23120	COG2197	response regulator
HUT06_RS23125	COG4585	Histidine kinase
HUT06_RS23135	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT06_RS23140	COG0822	iron-sulfur transferase activity
HUT06_RS23150	COG0396	ATPase activity
HUT06_RS23160	COG0719	Fe-S assembly protein
HUT06_RS23180	COG0531	amino acid
HUT06_RS23185	COG0549	Belongs to the carbamate kinase family
HUT06_RS23190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT06_RS23200	COG1131	(ABC) transporter
HUT06_RS23215	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT06_RS23220	COG1796	DNA polymerase
HUT06_RS23220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT06_RS23225	COG1612	heme a metabolic process
HUT06_RS23235	COG0109	protoheme IX farnesyltransferase activity
HUT06_RS23245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT06_RS23255	COG0166	Belongs to the GPI family
HUT06_RS23260	COG0166	Belongs to the GPI family
HUT06_RS23275	COG0363	glucosamine-6-phosphate deaminase activity
HUT06_RS23280	COG1376	ErfK ybiS ycfS ynhG family protein
HUT06_RS23300	COG4585	Histidine kinase
HUT06_RS23310	COG2197	response regulator
HUT06_RS23330	COG1695	Transcriptional regulator
HUT06_RS23340	COG4585	Histidine kinase
HUT06_RS23345	COG2197	response regulator
HUT06_RS23355	COG2409	Drug exporters of the RND superfamily
HUT06_RS23370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT06_RS23370	COG0574	Belongs to the PEP-utilizing enzyme family
HUT06_RS23400	COG0445	tRNA wobble uridine modification
HUT06_RS23410	COG2755	lipolytic protein G-D-S-L family
HUT06_RS23440	COG1309	transcriptional regulator
HUT06_RS23475	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS23495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT06_RS23540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS23545	COG2301	Belongs to the HpcH HpaI aldolase family
HUT06_RS23555	COG2079	MmgE PrpD family protein
HUT06_RS23590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT06_RS23600	COG1522	sequence-specific DNA binding
HUT06_RS23610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUT06_RS23615	COG0149	triose-phosphate isomerase activity
HUT06_RS23620	COG0126	phosphoglycerate kinase activity
HUT06_RS23625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT06_RS23645	COG1481	regulation of sporulation
HUT06_RS23650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT06_RS23655	COG1660	Displays ATPase and GTPase activities
HUT06_RS23660	COG0322	excinuclease ABC activity
HUT06_RS23675	COG2146	nitrite reductase [NAD(P)H] activity
HUT06_RS23680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT06_RS23685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT06_RS23700	COG3903	Transcriptional regulator
HUT06_RS23700	COG3629	intracellular signal transduction
HUT06_RS23710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT06_RS23770	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS23805	COG0497	DNA recombination
HUT06_RS23810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT06_RS23830	COG0647	UMP catabolic process
HUT06_RS23890	COG1024	Enoyl-CoA hydratase
HUT06_RS23910	COG0673	inositol 2-dehydrogenase activity
HUT06_RS23940	COG1140	nitrate reductase beta subunit
HUT06_RS23980	COG0076	glutamate decarboxylase activity
HUT06_RS23985	COG0247	lactate metabolic process
HUT06_RS23985	COG0277	FAD linked oxidase domain protein
HUT06_RS23990	COG1414	Transcriptional regulator
HUT06_RS23995	COG3971	2-oxopent-4-enoate hydratase activity
HUT06_RS24035	COG0513	Belongs to the DEAD box helicase family
HUT06_RS24040	COG1278	Cold shock
HUT06_RS24070	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS24125	COG0024	Methionine aminopeptidase
HUT06_RS24160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT06_RS24165	COG1278	Cold shock
HUT06_RS24215	COG0439	Biotin carboxylase
HUT06_RS24235	COG4948	Mandelate Racemase Muconate Lactonizing
HUT06_RS24255	COG1175	transmembrane transport
HUT06_RS24260	COG0395	ABC-type sugar transport system, permease component
HUT06_RS24270	COG0673	inositol 2-dehydrogenase activity
HUT06_RS24290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT06_RS24295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT06_RS24300	COG0829	nickel cation binding
HUT06_RS24305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT06_RS24310	COG0830	nickel cation binding
HUT06_RS24325	COG0831	urea catabolic process
HUT06_RS24330	COG4413	Urea transporter
HUT06_RS24340	COG0531	amino acid
HUT06_RS24345	COG2301	Belongs to the HpcH HpaI aldolase family
HUT06_RS24350	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS24370	COG2030	dehydratase
HUT06_RS24385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS24390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS24395	COG2030	dehydratase
HUT06_RS24410	COG2188	Transcriptional regulator
HUT06_RS24415	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS24435	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS24480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT06_RS24485	COG0747	negative chemotaxis
HUT06_RS24490	COG0444	Belongs to the ABC transporter superfamily
HUT06_RS24495	COG4608	Belongs to the ABC transporter superfamily
HUT06_RS24510	COG1414	Transcriptional regulator
HUT06_RS24530	COG3976	FMN-binding domain protein
HUT06_RS24530	COG0431	NADPH-dependent FMN reductase
HUT06_RS24530	COG1053	succinate dehydrogenase
HUT06_RS24580	COG1414	Transcriptional regulator
HUT06_RS24600	COG1846	Transcriptional regulator
HUT06_RS24630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT06_RS24635	COG1309	transcriptional regulator
HUT06_RS24665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT06_RS24670	COG0531	amino acid
HUT06_RS24675	COG1349	DNA-binding transcription factor activity
HUT06_RS24680	COG1309	transcriptional regulator
HUT06_RS24685	COG2130	NADP-dependent
HUT06_RS24690	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT06_RS24690	COG1902	pentaerythritol trinitrate reductase activity
HUT06_RS24700	COG4585	Histidine kinase
HUT06_RS24705	COG2197	response regulator
HUT06_RS24715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT06_RS24725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT06_RS24730	COG1024	Enoyl-CoA hydratase
HUT06_RS24735	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HUT06_RS24775	COG1131	(ABC) transporter
HUT06_RS24825	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS24830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT06_RS24835	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HUT06_RS24840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS24850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS24855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HUT06_RS24865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT06_RS24870	COG1228	amidohydrolase
HUT06_RS24875	COG1819	glycosyl
HUT06_RS24895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT06_RS24915	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS24920	COG0251	oxidation-reduction process
HUT06_RS24945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HUT06_RS24960	COG2770	Histidine kinase
HUT06_RS24960	COG2208	phosphoserine phosphatase activity
HUT06_RS24970	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT06_RS24980	COG3618	amidohydrolase
HUT06_RS25020	COG4213	ABC transporter substrate-binding protein
HUT06_RS25025	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS25030	COG1129	ABC transporter
HUT06_RS25045	COG1024	Enoyl-CoA hydratase
HUT06_RS25065	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT06_RS25105	COG0640	Transcriptional regulator
HUT06_RS25115	COG2814	Major facilitator Superfamily
HUT06_RS25130	COG2130	NADP-dependent
HUT06_RS25135	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT06_RS25150	COG2365	Tyrosine phosphatase family
HUT06_RS25205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT06_RS25210	COG1595	DNA-templated transcription, initiation
HUT06_RS25230	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT06_RS25230	COG1902	pentaerythritol trinitrate reductase activity
HUT06_RS25235	COG2267	carboxylic ester hydrolase activity
HUT06_RS25240	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT06_RS25250	COG1129	ABC transporter
HUT06_RS25255	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS25260	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS25265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT06_RS25275	COG1414	Transcriptional regulator
HUT06_RS25285	COG0800	Aldolase
HUT06_RS25295	COG0251	oxidation-reduction process
HUT06_RS25305	COG0477	Major facilitator Superfamily
HUT06_RS25325	COG0596	Alpha beta hydrolase
HUT06_RS25330	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HUT06_RS25335	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUT06_RS25340	COG2197	response regulator
HUT06_RS25345	COG4585	Histidine kinase
HUT06_RS25355	COG1136	(ABC) transporter
HUT06_RS25385	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUT06_RS25390	COG0659	secondary active sulfate transmembrane transporter activity
HUT06_RS25395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT06_RS25400	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT06_RS25405	COG3842	ATPase activity
HUT06_RS25455	COG1335	isochorismatase
HUT06_RS25485	COG0436	Aminotransferase
HUT06_RS25490	COG1802	Transcriptional regulator
HUT06_RS25625	COG0416	fatty acid biosynthetic process
HUT06_RS25635	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HUT06_RS25645	COG1233	COG1233 Phytoene dehydrogenase and related
HUT06_RS25685	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HUT06_RS25700	COG0726	polysaccharide deacetylase
HUT06_RS25720	COG1131	(ABC) transporter
HUT06_RS25740	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT06_RS25750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT06_RS25760	COG2205	protein histidine kinase activity
HUT06_RS25765	COG0745	RESPONSE REGULATOR receiver
HUT06_RS25770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT06_RS25770	COG1017	nitric oxide dioxygenase activity
HUT06_RS25820	COG1233	COG1233 Phytoene dehydrogenase and related
HUT06_RS25830	COG3620	sequence-specific DNA binding
HUT06_RS25830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUT06_RS25830	COG0617	tRNA 3'-terminal CCA addition
HUT06_RS25870	COG0589	response to stress
HUT06_RS25875	COG0531	amino acid
HUT06_RS25885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT06_RS25890	COG0549	Belongs to the carbamate kinase family
HUT06_RS25970	COG0589	response to stress
HUT06_RS26040	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS26045	COG1024	Enoyl-CoA hydratase
HUT06_RS26050	COG2267	carboxylic ester hydrolase activity
HUT06_RS26060	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS26065	COG1024	Enoyl-CoA hydratase
HUT06_RS26085	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS26100	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS26105	COG0683	leucine binding
HUT06_RS26190	COG3328	transposase activity
HUT06_RS26235	COG0383	alpha-mannosidase activity
HUT06_RS26240	COG0613	PHP domain protein
HUT06_RS26245	COG3842	ATPase activity
HUT06_RS26250	COG0395	ABC-type sugar transport system, permease component
HUT06_RS26260	COG2182	Extracellular solute-binding protein
HUT06_RS26270	COG0640	Transcriptional regulator
HUT06_RS26320	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT06_RS26360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS26365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT06_RS26415	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS26445	COG0437	4 iron, 4 sulfur cluster binding
HUT06_RS26470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT06_RS26480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT06_RS26520	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS26530	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT06_RS26545	COG1609	Transcriptional regulator
HUT06_RS26555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT06_RS26570	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HUT06_RS26585	COG0431	NADPH-dependent FMN reductase
HUT06_RS26590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS26595	COG0789	Transcriptional regulator
HUT06_RS26605	COG2353	YceI-like domain
HUT06_RS26650	COG0596	Alpha beta hydrolase
HUT06_RS26655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT06_RS26660	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS26665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT06_RS26670	COG3321	synthase
HUT06_RS26670	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS26670	COG0604	alcohol dehydrogenase
HUT06_RS26685	COG3509	depolymerase
HUT06_RS26700	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HUT06_RS26705	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT06_RS26750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT06_RS26755	COG1968	undecaprenyl-diphosphatase activity
HUT06_RS26770	COG0402	S-adenosylhomocysteine deaminase activity
HUT06_RS26775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS26795	COG0604	alcohol dehydrogenase
HUT06_RS26795	COG3321	synthase
HUT06_RS26795	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS26800	COG1414	Transcriptional regulator
HUT06_RS26840	COG2072	flavoprotein involved in K transport
HUT06_RS26855	COG1846	Transcriptional regulator
HUT06_RS26855	COG1940	carbohydrate kinase activity
HUT06_RS26860	COG1126	abc transporter atp-binding protein
HUT06_RS26865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT06_RS26870	COG0765	amino acid transport
HUT06_RS26875	COG0765	amino acid transport
HUT06_RS26885	COG3142	Participates in the control of copper homeostasis
HUT06_RS26890	COG0366	Alpha amylase catalytic
HUT06_RS26905	COG0366	Alpha amylase catalytic
HUT06_RS26910	COG3281	Trehalose synthase
HUT06_RS26925	COG1116	anion transmembrane transporter activity
HUT06_RS26930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT06_RS26935	COG1077	Cell shape determining protein MreB Mrl
HUT06_RS26950	COG2814	Major facilitator Superfamily
HUT06_RS26955	COG4715	Zinc finger, swim domain protein
HUT06_RS26960	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT06_RS26965	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HUT06_RS26970	COG0714	Associated with various cellular activities
HUT06_RS26975	COG3831	ATPase activity
HUT06_RS26995	COG0596	Alpha beta hydrolase
HUT06_RS27005	COG0626	cystathionine gamma-synthase activity
HUT06_RS27015	COG3831	ATPase activity
HUT06_RS27020	COG3831	ATPase activity
HUT06_RS27025	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT06_RS27035	COG0174	glutamine synthetase
HUT06_RS27080	COG1309	transcriptional regulator
HUT06_RS27085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT06_RS27090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUT06_RS27100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT06_RS27100	COG0235	Class ii aldolase
HUT06_RS27110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT06_RS27115	COG0587	DNA-directed DNA polymerase activity
HUT06_RS27125	COG0248	Ppx GppA phosphatase
HUT06_RS27135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT06_RS27145	COG2814	Major facilitator Superfamily
HUT06_RS27155	COG0656	L-ascorbic acid biosynthetic process
HUT06_RS27170	COG3250	beta-galactosidase activity
HUT06_RS27175	COG3250	beta-galactosidase activity
HUT06_RS27200	COG3347	Dehydrogenase
HUT06_RS27200	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS27210	COG3254	rhamnose metabolic process
HUT06_RS27215	COG1879	ABC-type sugar transport system periplasmic component
HUT06_RS27220	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS27230	COG1129	ABC transporter
HUT06_RS27240	COG0247	lactate metabolic process
HUT06_RS27245	COG1139	Iron-sulfur cluster binding protein
HUT06_RS27250	COG1556	Lactate utilization protein
HUT06_RS27255	COG1070	Carbohydrate kinase
HUT06_RS27260	COG1672	PFAM Archaeal ATPase
HUT06_RS27260	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT06_RS27280	COG3467	pyridoxamine 5'-phosphate
HUT06_RS27320	COG1643	Atp-dependent helicase
HUT06_RS27345	COG3284	Transcriptional regulator
HUT06_RS27365	COG0183	Belongs to the thiolase family
HUT06_RS27395	COG2755	lipolytic protein G-D-S-L family
HUT06_RS27400	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HUT06_RS27410	COG3695	enzyme binding
HUT06_RS27440	COG2340	Cysteine-rich secretory protein family
HUT06_RS27455	COG3321	synthase
HUT06_RS27455	COG0604	alcohol dehydrogenase
HUT06_RS27455	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS27490	COG1063	alcohol dehydrogenase
HUT06_RS27510	COG1401	restriction endodeoxyribonuclease activity
HUT06_RS27520	COG1733	regulation of RNA biosynthetic process
HUT06_RS27580	COG0210	DNA helicase
HUT06_RS27585	COG0515	serine threonine protein kinase
HUT06_RS27595	COG0328	RNA-DNA hybrid ribonuclease activity
HUT06_RS27630	COG2409	Drug exporters of the RND superfamily
HUT06_RS27635	COG2197	response regulator
HUT06_RS27640	COG4585	Histidine kinase
HUT06_RS27665	COG0477	Major facilitator Superfamily
HUT06_RS27705	COG0668	transmembrane transport
HUT06_RS27725	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS27730	COG1672	PFAM Archaeal ATPase
HUT06_RS27730	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT06_RS27750	COG0515	serine threonine protein kinase
HUT06_RS27760	COG1132	(ABC) transporter
HUT06_RS27770	COG2197	response regulator
HUT06_RS27785	COG1070	Carbohydrate kinase
HUT06_RS27790	COG1349	DNA-binding transcription factor activity
HUT06_RS27805	COG3250	beta-galactosidase activity
HUT06_RS27815	COG1175	transmembrane transport
HUT06_RS27820	COG0395	ABC-type sugar transport system, permease component
HUT06_RS27850	COG3251	PFAM MbtH domain protein
HUT06_RS27855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT06_RS27860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT06_RS27875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT06_RS27890	COG0604	alcohol dehydrogenase
HUT06_RS27900	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS27930	COG0235	Class ii aldolase
HUT06_RS27940	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS27955	COG0443	Heat shock 70 kDa protein
HUT06_RS27980	COG0778	Nitroreductase
HUT06_RS27985	COG1309	transcriptional regulator
HUT06_RS27995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT06_RS28025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUT06_RS28035	COG3473	Maleate cis-trans isomerase
HUT06_RS28045	COG2186	Transcriptional regulator
HUT06_RS28055	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS28065	COG1309	transcriptional regulator
HUT06_RS28080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS28100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT06_RS28125	COG0714	Associated with various cellular activities
HUT06_RS28145	COG0714	Associated with various cellular activities
HUT06_RS28150	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HUT06_RS28155	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT06_RS28165	COG0515	serine threonine protein kinase
HUT06_RS28165	COG2815	serine threonine protein kinase
HUT06_RS28175	COG0640	Transcriptional regulator
HUT06_RS28190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT06_RS28210	COG1597	lipid kinase activity
HUT06_RS28220	COG0667	Aldo Keto reductase
HUT06_RS28275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT06_RS28295	COG2132	Multicopper oxidase
HUT06_RS28315	COG0419	ATPase involved in DNA repair
HUT06_RS28320	COG0420	3'-5' exonuclease activity
HUT06_RS28325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT06_RS28325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT06_RS28330	COG0590	tRNA wobble adenosine to inosine editing
HUT06_RS28395	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT06_RS28405	COG3718	enzyme involved in inositol metabolism
HUT06_RS28420	COG0673	inositol 2-dehydrogenase activity
HUT06_RS28435	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT06_RS28470	COG0456	acetyltransferase
HUT06_RS28495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT06_RS28510	COG0386	Belongs to the glutathione peroxidase family
HUT06_RS28530	COG1316	TRANSCRIPTIONal
HUT06_RS28535	COG1132	(ABC) transporter
HUT06_RS28540	COG0464	growth
HUT06_RS28565	COG2018	Roadblock/LC7 domain
HUT06_RS28570	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUT06_RS28585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT06_RS28600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT06_RS28605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT06_RS28610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT06_RS28610	COG1116	anion transmembrane transporter activity
HUT06_RS28705	COG0175	sulfate reduction
HUT06_RS28725	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS28745	COG2197	response regulator
HUT06_RS28750	COG4585	Histidine kinase
HUT06_RS28845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUT06_RS28855	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT06_RS28870	COG0702	epimerase
HUT06_RS28880	COG0789	Transcriptional regulator
HUT06_RS28885	COG1309	transcriptional regulator
HUT06_RS28890	COG0477	Major facilitator Superfamily
HUT06_RS28900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT06_RS28910	COG1349	DNA-binding transcription factor activity
HUT06_RS28935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUT06_RS28945	COG1793	dna ligase
HUT06_RS28950	COG3540	Alkaline phosphatase
HUT06_RS28960	COG2186	Transcriptional regulator
HUT06_RS28965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT06_RS28975	COG2936	dipeptidyl-peptidase activity
HUT06_RS28990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT06_RS29025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT06_RS29045	COG0672	)-iron permease
HUT06_RS29055	COG0577	efflux transmembrane transporter activity
HUT06_RS29060	COG1136	(ABC) transporter
HUT06_RS29060	COG0577	efflux transmembrane transporter activity
HUT06_RS29080	COG0745	RESPONSE REGULATOR receiver
HUT06_RS29085	COG2205	protein histidine kinase activity
HUT06_RS29090	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS29160	COG3559	Exporter of polyketide antibiotics
HUT06_RS29165	COG1131	(ABC) transporter
HUT06_RS29170	COG2267	carboxylic ester hydrolase activity
HUT06_RS29190	COG2124	cytochrome p450
HUT06_RS29225	COG2226	methyltransferase
HUT06_RS29225	COG3433	isochorismatase activity
HUT06_RS29225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT06_RS29240	COG2226	methyltransferase
HUT06_RS29240	COG3433	isochorismatase activity
HUT06_RS29240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT06_RS29260	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HUT06_RS29275	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS29275	COG3321	synthase
HUT06_RS29275	COG0604	alcohol dehydrogenase
HUT06_RS29285	COG0475	glutathione-regulated potassium exporter activity
HUT06_RS29290	COG0644	oxidoreductase
HUT06_RS29295	COG3903	Transcriptional regulator
HUT06_RS29295	COG3629	intracellular signal transduction
HUT06_RS29300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT06_RS29300	COG0825	malonyl-CoA metabolic process
HUT06_RS29305	COG0511	ligase activity, forming carbon-carbon bonds
HUT06_RS29310	COG0439	Biotin carboxylase
HUT06_RS29320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS29345	COG3629	intracellular signal transduction
HUT06_RS29355	COG0183	Belongs to the thiolase family
HUT06_RS29360	COG1024	Enoyl-CoA hydratase
HUT06_RS29360	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT06_RS29365	COG0531	amino acid
HUT06_RS29385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT06_RS29390	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT06_RS29405	COG0395	ABC-type sugar transport system, permease component
HUT06_RS29430	COG0667	Aldo Keto reductase
HUT06_RS29435	COG1280	lysine exporter protein (LysE YggA)
HUT06_RS29440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT06_RS29455	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT06_RS29475	COG1562	ergosterol biosynthetic process
HUT06_RS29485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT06_RS29495	COG1657	PFAM Prenyltransferase squalene oxidase
HUT06_RS29535	COG0800	Aldolase
HUT06_RS29540	COG0837	glucose binding
HUT06_RS29565	COG0484	heat shock protein binding
HUT06_RS29575	COG0484	heat shock protein binding
HUT06_RS29585	COG0484	heat shock protein binding
HUT06_RS29635	COG0657	acetylesterase activity
HUT06_RS29660	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS29680	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT06_RS29680	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT06_RS29685	COG3541	Predicted nucleotidyltransferase
HUT06_RS29695	COG1653	transport
HUT06_RS29710	COG0366	Alpha amylase catalytic
HUT06_RS29715	COG1609	Transcriptional regulator
HUT06_RS29730	COG0395	ABC-type sugar transport system, permease component
HUT06_RS29735	COG2723	6-phospho-beta-galactosidase activity
HUT06_RS29780	COG2814	Major facilitator Superfamily
HUT06_RS29790	COG1501	Belongs to the glycosyl hydrolase 31 family
HUT06_RS29795	COG0395	ABC-type sugar transport system, permease component
HUT06_RS29800	COG1175	transmembrane transport
HUT06_RS29815	COG4336	lyase activity
HUT06_RS29820	COG1984	allophanate hydrolase subunit 2
HUT06_RS29825	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUT06_RS29830	COG1914	H( )-stimulated, divalent metal cation uptake system
HUT06_RS29835	COG2188	Transcriptional regulator
HUT06_RS29840	COG1802	Transcriptional regulator
HUT06_RS29845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT06_RS29850	COG0022	dehydrogenase e1 component
HUT06_RS29855	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT06_RS29875	COG1595	DNA-templated transcription, initiation
HUT06_RS29905	COG1846	Transcriptional regulator
HUT06_RS29905	COG1940	carbohydrate kinase activity
HUT06_RS29910	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT06_RS29920	COG4106	trans-aconitate 2-methyltransferase activity
HUT06_RS29930	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT06_RS29970	COG1482	cell wall glycoprotein biosynthetic process
HUT06_RS29980	COG1522	sequence-specific DNA binding
HUT06_RS29985	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS30000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT06_RS30005	COG2226	methyltransferase
HUT06_RS30020	COG0477	Major facilitator Superfamily
HUT06_RS30040	COG4552	Acetyltransferase involved in intracellular survival and related
HUT06_RS30045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT06_RS30050	COG0531	amino acid
HUT06_RS30055	COG0569	domain protein
HUT06_RS30080	COG1136	(ABC) transporter
HUT06_RS30105	COG0756	dUTP diphosphatase activity
HUT06_RS30145	COG0706	membrane insertase activity
HUT06_RS30155	COG0525	valine-tRNA ligase activity
HUT06_RS30180	COG2205	protein histidine kinase activity
HUT06_RS30185	COG0745	RESPONSE REGULATOR receiver
HUT06_RS30195	COG0483	inositol monophosphate 1-phosphatase activity
HUT06_RS30205	COG0739	heme binding
HUT06_RS30230	COG3402	PFAM membrane-flanked domain
HUT06_RS30250	COG1252	NADH dehydrogenase
HUT06_RS30255	COG1881	PFAM PEBP family protein
HUT06_RS30265	COG0659	secondary active sulfate transmembrane transporter activity
HUT06_RS30290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT06_RS30295	COG4608	Belongs to the ABC transporter superfamily
HUT06_RS30300	COG0444	Belongs to the ABC transporter superfamily
HUT06_RS30310	COG0747	negative chemotaxis
HUT06_RS30315	COG2186	Transcriptional regulator
HUT06_RS30335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT06_RS30465	COG0517	IMP dehydrogenase activity
HUT06_RS30475	COG0464	growth
HUT06_RS30480	COG4451	ribulose bisphosphate carboxylase, small
HUT06_RS30485	COG1850	ribulose-bisphosphate carboxylase activity
HUT06_RS30490	COG0583	DNA-binding transcription factor activity
HUT06_RS30500	COG3268	Saccharopine dehydrogenase
HUT06_RS30510	COG2197	response regulator
HUT06_RS30515	COG0572	uridine kinase
HUT06_RS30540	COG0432	Pfam Uncharacterised protein family UPF0047
HUT06_RS30550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT06_RS30575	COG0477	Major facilitator Superfamily
HUT06_RS30580	COG1846	Transcriptional regulator
HUT06_RS30590	COG3385	transposase activity
HUT06_RS30605	COG0667	Aldo Keto reductase
HUT06_RS30610	COG1309	transcriptional regulator
HUT06_RS30615	COG2378	regulation of single-species biofilm formation
HUT06_RS30630	COG2267	carboxylic ester hydrolase activity
HUT06_RS30635	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS30660	COG0410	ABC transporter
HUT06_RS30695	COG1796	DNA polymerase
HUT06_RS30695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT06_RS30700	COG4585	Histidine kinase
HUT06_RS30705	COG2197	response regulator
HUT06_RS30735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT06_RS30740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT06_RS30820	COG2267	carboxylic ester hydrolase activity
HUT06_RS30830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT06_RS30835	COG1309	transcriptional regulator
HUT06_RS30890	COG1464	Belongs to the NlpA lipoprotein family
HUT06_RS30895	COG2011	ABC-type metal ion transport system permease component
HUT06_RS30900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT06_RS30930	COG1309	transcriptional regulator
HUT06_RS30935	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS30950	COG4585	Histidine kinase
HUT06_RS30955	COG1131	(ABC) transporter
HUT06_RS30970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT06_RS31040	COG2197	response regulator
HUT06_RS31050	COG0187	DNA topoisomerase II activity
HUT06_RS31055	COG1131	(ABC) transporter
HUT06_RS31075	COG3022	response to hydroperoxide
HUT06_RS31080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUT06_RS31085	COG4191	Histidine kinase
HUT06_RS31095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT06_RS31140	COG1984	allophanate hydrolase subunit 2
HUT06_RS31160	COG0596	Alpha beta hydrolase
HUT06_RS31165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT06_RS31175	COG0778	Nitroreductase
HUT06_RS31175	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT06_RS31230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT06_RS31235	COG0495	leucyl-tRNA aminoacylation
HUT06_RS31240	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS31250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT06_RS31255	COG0596	Alpha beta hydrolase
HUT06_RS31270	COG0667	Aldo Keto reductase
HUT06_RS31275	COG1793	dna ligase
HUT06_RS31295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT06_RS31300	COG0277	FAD linked oxidase domain protein
HUT06_RS31330	COG0436	Aminotransferase
HUT06_RS31335	COG0577	efflux transmembrane transporter activity
HUT06_RS31340	COG1136	(ABC) transporter
HUT06_RS31370	COG1683	Conserved Protein
HUT06_RS31460	COG0406	alpha-ribazole phosphatase activity
HUT06_RS31470	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT06_RS31475	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HUT06_RS31485	COG0501	Belongs to the peptidase M48B family
HUT06_RS31495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT06_RS31500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUT06_RS31505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT06_RS31510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT06_RS31515	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT06_RS31520	COG1530	ribonuclease E activity
HUT06_RS31535	COG0772	Belongs to the SEDS family
HUT06_RS31555	COG1077	Cell shape determining protein MreB Mrl
HUT06_RS31560	COG0105	UTP biosynthetic process
HUT06_RS31575	COG0285	dihydrofolate synthase activity
HUT06_RS31590	COG0525	valine-tRNA ligase activity
HUT06_RS31605	COG2197	response regulator
HUT06_RS31610	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT06_RS31615	COG0740	serine-type endopeptidase activity
HUT06_RS31620	COG0740	serine-type endopeptidase activity
HUT06_RS31625	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT06_RS31635	COG2183	response to ionizing radiation
HUT06_RS31670	COG1309	transcriptional regulator
HUT06_RS31685	COG1733	regulation of RNA biosynthetic process
HUT06_RS31725	COG3467	pyridoxamine 5'-phosphate
HUT06_RS31730	COG2315	Protein conserved in bacteria
HUT06_RS31735	COG2315	Protein conserved in bacteria
HUT06_RS31755	COG1595	DNA-templated transcription, initiation
HUT06_RS31780	COG3540	Alkaline phosphatase
HUT06_RS31810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT06_RS31820	COG0596	Alpha beta hydrolase
HUT06_RS31830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS31840	COG3291	Pkd domain containing protein
HUT06_RS31845	COG4608	Belongs to the ABC transporter superfamily
HUT06_RS31855	COG0601	transmembrane transport
HUT06_RS31860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT06_RS31870	COG0006	proline dipeptidase activity
HUT06_RS31880	COG1802	Transcriptional regulator
HUT06_RS31895	COG1802	Transcriptional regulator
HUT06_RS31920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT06_RS31925	COG3938	Belongs to the proline racemase family
HUT06_RS31965	COG5398	heme oxygenase
HUT06_RS31970	COG1120	ATPase activity
HUT06_RS31975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS31980	COG4558	Periplasmic binding protein
HUT06_RS32010	COG1063	alcohol dehydrogenase
HUT06_RS32070	COG4213	ABC transporter substrate-binding protein
HUT06_RS32075	COG1129	ABC transporter
HUT06_RS32080	COG4214	carbohydrate transport
HUT06_RS32085	COG1609	Transcriptional regulator
HUT06_RS32110	COG2160	L-arabinose isomerase activity
HUT06_RS32115	COG0235	Class ii aldolase
HUT06_RS32120	COG1609	Transcriptional regulator
HUT06_RS32125	COG0477	Major facilitator Superfamily
HUT06_RS32130	COG1473	amidohydrolase
HUT06_RS32145	COG0243	molybdopterin cofactor binding
HUT06_RS32145	COG3383	formate dehydrogenase (NAD+) activity
HUT06_RS32150	COG3383	formate dehydrogenase (NAD+) activity
HUT06_RS32150	COG0243	molybdopterin cofactor binding
HUT06_RS32155	COG0709	Synthesizes selenophosphate from selenide and ATP
HUT06_RS32175	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS32220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS32235	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS32270	COG2409	Drug exporters of the RND superfamily
HUT06_RS32275	COG1595	DNA-templated transcription, initiation
HUT06_RS32285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT06_RS32285	COG0519	Catalyzes the synthesis of GMP from XMP
HUT06_RS32295	COG0154	amidase activity
HUT06_RS32300	COG5002	protein histidine kinase activity
HUT06_RS32305	COG0515	serine threonine protein kinase
HUT06_RS32305	COG2815	serine threonine protein kinase
HUT06_RS32320	COG0698	ribose 5-phosphate isomerase
HUT06_RS32335	COG1122	ATPase activity
HUT06_RS32350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT06_RS32370	COG0154	amidase activity
HUT06_RS32380	COG0129	dihydroxy-acid dehydratase activity
HUT06_RS32400	COG1505	serine-type exopeptidase activity
HUT06_RS32425	COG0668	transmembrane transport
HUT06_RS32435	COG0366	Alpha amylase catalytic
HUT06_RS32445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT06_RS32480	COG3706	GGDEF domain
HUT06_RS32485	COG0629	single-stranded DNA binding
HUT06_RS32500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT06_RS32500	COG1648	precorrin-2 dehydrogenase activity
HUT06_RS32505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT06_RS32530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT06_RS32555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS32560	COG0028	Belongs to the TPP enzyme family
HUT06_RS32575	COG4585	Histidine kinase
HUT06_RS32580	COG2197	response regulator
HUT06_RS32595	COG0587	DNA-directed DNA polymerase activity
HUT06_RS32610	COG1309	transcriptional regulator
HUT06_RS32655	COG1492	cobalamin metabolic process
HUT06_RS32670	COG3328	transposase activity
HUT06_RS32700	COG0515	serine threonine protein kinase
HUT06_RS32760	COG0583	DNA-binding transcription factor activity
HUT06_RS32770	COG1595	DNA-templated transcription, initiation
HUT06_RS32780	COG3485	protocatechuate 3,4-dioxygenase
HUT06_RS32795	COG4977	sequence-specific DNA binding
HUT06_RS32845	COG0740	serine-type endopeptidase activity
HUT06_RS32850	COG0740	serine-type endopeptidase activity
HUT06_RS32855	COG1396	sequence-specific DNA binding
HUT06_RS32860	COG2267	carboxylic ester hydrolase activity
HUT06_RS32870	COG4106	trans-aconitate 2-methyltransferase activity
HUT06_RS32890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT06_RS32895	COG4221	oxidoreductase activity
HUT06_RS32915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUT06_RS32915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT06_RS32920	COG0785	Cytochrome C biogenesis protein
HUT06_RS32930	COG0601	transmembrane transport
HUT06_RS32935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT06_RS32940	COG1124	(ABC) transporter
HUT06_RS32945	COG1132	(ABC) transporter
HUT06_RS32950	COG1132	(ABC) transporter
HUT06_RS32955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT06_RS32960	COG1120	ATPase activity
HUT06_RS32965	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS32970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS32995	COG1802	Transcriptional regulator
HUT06_RS33000	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS33005	COG2234	aminopeptidase activity
HUT06_RS33030	COG1136	(ABC) transporter
HUT06_RS33030	COG0577	efflux transmembrane transporter activity
HUT06_RS33040	COG2197	response regulator
HUT06_RS33060	COG1053	succinate dehydrogenase
HUT06_RS33065	COG1120	ATPase activity
HUT06_RS33070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS33075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT06_RS33135	COG0583	DNA-binding transcription factor activity
HUT06_RS33140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT06_RS33170	COG3261	NADH dehydrogenase
HUT06_RS33170	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HUT06_RS33175	COG0651	ATP synthesis coupled electron transport
HUT06_RS33185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT06_RS33195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS33220	COG3469	chitinase activity
HUT06_RS33400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT06_RS33400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT06_RS33425	COG3831	ATPase activity
HUT06_RS33470	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUT06_RS33480	COG3903	Transcriptional regulator
HUT06_RS33480	COG3629	intracellular signal transduction
HUT06_RS33510	COG2197	response regulator
HUT06_RS33630	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUT06_RS33705	COG1047	Peptidyl-prolyl cis-trans
HUT06_RS33710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT06_RS33785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT06_RS33795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUT06_RS33805	COG2197	response regulator
HUT06_RS33820	COG0596	Alpha beta hydrolase
HUT06_RS33840	COG0583	DNA-binding transcription factor activity
HUT06_RS33845	COG1216	Glycosyl transferase, family 2
HUT06_RS33845	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS33870	COG1053	succinate dehydrogenase
HUT06_RS33895	COG0431	NADPH-dependent FMN reductase
HUT06_RS33910	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS33920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT06_RS33925	COG0741	lytic transglycosylase activity
HUT06_RS33925	COG1196	nuclear chromosome segregation
HUT06_RS33925	COG0739	heme binding
HUT06_RS33935	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUT06_RS33950	COG3387	PFAM Glycoside hydrolase 15-related
HUT06_RS33955	COG1063	alcohol dehydrogenase
HUT06_RS33990	COG3629	intracellular signal transduction
HUT06_RS33990	COG3903	Transcriptional regulator
HUT06_RS34025	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT06_RS34055	COG0653	protein targeting
HUT06_RS34090	COG4993	Dehydrogenase
HUT06_RS34090	COG2010	Cytochrome c
HUT06_RS34095	COG3279	Response regulator of the LytR AlgR family
HUT06_RS34095	COG5000	phosphorelay sensor kinase activity
HUT06_RS34100	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT06_RS34110	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS34115	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS34120	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS34125	COG2723	6-phospho-beta-galactosidase activity
HUT06_RS34150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT06_RS34185	COG1902	pentaerythritol trinitrate reductase activity
HUT06_RS34240	COG0183	Belongs to the thiolase family
HUT06_RS34250	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS34260	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS34265	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS34295	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS34315	COG2855	membrane
HUT06_RS34340	COG0156	8-amino-7-oxononanoate synthase activity
HUT06_RS34345	COG2409	Drug exporters of the RND superfamily
HUT06_RS34365	COG1595	DNA-templated transcription, initiation
HUT06_RS34370	COG3631	Ketosteroid isomerase-related protein
HUT06_RS34385	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS34390	COG0183	Belongs to the thiolase family
HUT06_RS34410	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS34415	COG1309	transcriptional regulator
HUT06_RS34430	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS34465	COG1309	transcriptional regulator
HUT06_RS34490	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS34505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT06_RS34515	COG4608	Belongs to the ABC transporter superfamily
HUT06_RS34580	COG1053	succinate dehydrogenase
HUT06_RS34580	COG3976	FMN-binding domain protein
HUT06_RS34590	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS34605	COG1053	succinate dehydrogenase
HUT06_RS34610	COG2267	carboxylic ester hydrolase activity
HUT06_RS34615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT06_RS34625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS34665	COG1132	(ABC) transporter
HUT06_RS34680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUT06_RS34700	COG0675	Transposase, IS605 OrfB family
HUT06_RS34710	COG1584	GPR1 FUN34 yaaH family protein
HUT06_RS34725	COG1620	l-lactate permease
HUT06_RS34730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT06_RS34735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT06_RS34740	COG2080	2 iron, 2 sulfur cluster binding
HUT06_RS34805	COG1609	Transcriptional regulator
HUT06_RS34810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT06_RS34820	COG1116	anion transmembrane transporter activity
HUT06_RS34825	COG0673	inositol 2-dehydrogenase activity
HUT06_RS34860	COG0667	Aldo Keto reductase
HUT06_RS34895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUT06_RS34910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT06_RS34915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT06_RS34920	COG0477	Major facilitator Superfamily
HUT06_RS34960	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HUT06_RS34960	COG2508	Transcriptional regulator
HUT06_RS34970	COG1309	transcriptional regulator
HUT06_RS34975	COG0586	Pfam SNARE associated Golgi protein
HUT06_RS34990	COG3328	transposase activity
HUT06_RS35005	COG1834	amidinotransferase
HUT06_RS35035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT06_RS35045	COG0204	Acyl-transferase
HUT06_RS35065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT06_RS35070	COG1846	Transcriptional regulator
HUT06_RS35110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT06_RS35115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT06_RS35130	COG1309	transcriptional regulator
HUT06_RS35260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT06_RS35285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT06_RS35295	COG1127	ABC transporter
HUT06_RS35305	COG1309	transcriptional regulator
HUT06_RS35320	COG1309	transcriptional regulator
HUT06_RS35350	COG1793	dna ligase
HUT06_RS35360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT06_RS35365	COG0750	zinc metalloprotease
HUT06_RS35375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT06_RS35380	COG0509	glycine decarboxylation via glycine cleavage system
HUT06_RS35385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT06_RS35390	COG1760	l-serine dehydratase
HUT06_RS35410	COG0789	Transcriptional regulator
HUT06_RS35430	COG0183	Belongs to the thiolase family
HUT06_RS35450	COG4565	transcriptional regulatory protein
HUT06_RS35455	COG3290	protein histidine kinase activity
HUT06_RS35485	COG2968	Membrane
HUT06_RS35490	COG1486	melibiose metabolic process
HUT06_RS35515	COG1606	tRNA processing
HUT06_RS35520	COG1691	(AIR) carboxylase
HUT06_RS35525	COG1691	(AIR) carboxylase
HUT06_RS35530	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HUT06_RS35570	COG4566	intracellular signal transduction
HUT06_RS35575	COG2197	response regulator
HUT06_RS35590	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS35590	COG0204	Acyl-transferase
HUT06_RS35615	COG1595	DNA-templated transcription, initiation
HUT06_RS35625	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT06_RS35630	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT06_RS35635	COG1234	tRNA 3'-trailer cleavage
HUT06_RS35640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUT06_RS35670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUT06_RS35680	COG1335	isochorismatase
HUT06_RS35685	COG3265	gluconokinase activity
HUT06_RS35705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT06_RS35730	COG1678	Uncharacterized ACR, COG1678
HUT06_RS35760	COG2814	Major facilitator Superfamily
HUT06_RS35770	COG0183	Belongs to the thiolase family
HUT06_RS35785	COG0628	permease
HUT06_RS35805	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT06_RS35830	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT06_RS35845	COG1994	Peptidase M50
HUT06_RS35875	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS35895	COG1403	HNH endonuclease
HUT06_RS35945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT06_RS35950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT06_RS35955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT06_RS35960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUT06_RS35965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT06_RS35970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT06_RS35975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT06_RS35995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT06_RS36015	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT06_RS36020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUT06_RS36025	COG0254	rRNA binding
HUT06_RS36045	COG0083	homoserine kinase activity
HUT06_RS36050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT06_RS36055	COG0460	homoserine dehydrogenase
HUT06_RS36060	COG0019	diaminopimelate decarboxylase activity
HUT06_RS36065	COG0018	arginyl-trna synthetase
HUT06_RS36105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT06_RS36120	COG4585	Histidine kinase
HUT06_RS36145	COG0640	Transcriptional regulator
HUT06_RS36170	COG1657	PFAM Prenyltransferase squalene oxidase
HUT06_RS36180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUT06_RS36200	COG3835	regulator
HUT06_RS36235	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT06_RS36245	COG2508	Transcriptional regulator
HUT06_RS36275	COG0395	ABC-type sugar transport system, permease component
HUT06_RS36295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT06_RS36315	COG0596	Alpha beta hydrolase
HUT06_RS36325	COG2124	cytochrome p450
HUT06_RS36330	COG2130	NADP-dependent
HUT06_RS36340	COG0640	Transcriptional regulator
HUT06_RS36365	COG1132	(ABC) transporter
HUT06_RS36380	COG1316	TRANSCRIPTIONal
HUT06_RS36400	COG2211	Major facilitator Superfamily
HUT06_RS36415	COG1280	lysine exporter protein (LysE YggA)
HUT06_RS36420	COG1309	transcriptional regulator
HUT06_RS36425	COG2124	cytochrome p450
HUT06_RS36450	COG1090	epimerase
HUT06_RS36465	COG2072	flavoprotein involved in K transport
HUT06_RS36575	COG2197	response regulator
HUT06_RS36585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT06_RS36595	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS36610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUT06_RS36640	COG2124	cytochrome p450
HUT06_RS36645	COG4585	Histidine kinase
HUT06_RS36650	COG2197	response regulator
HUT06_RS36670	COG0515	serine threonine protein kinase
HUT06_RS36685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT06_RS36685	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT06_RS36720	COG0321	lipoyl(octanoyl) transferase activity
HUT06_RS36720	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUT06_RS36775	COG1511	domain protein
HUT06_RS36795	COG1846	Transcriptional regulator
HUT06_RS36805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT06_RS36825	COG1024	Enoyl-CoA hydratase
HUT06_RS36840	COG2070	2-Nitropropane dioxygenase
HUT06_RS36855	COG4981	capsule polysaccharide biosynthetic process
HUT06_RS36860	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS36865	COG1216	Glycosyl transferase, family 2
HUT06_RS36875	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS36890	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS36905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT06_RS36950	COG2814	Major facilitator Superfamily
HUT06_RS36960	COG3629	intracellular signal transduction
HUT06_RS36960	COG3903	Transcriptional regulator
HUT06_RS36965	COG0641	radical SAM
HUT06_RS36980	COG1053	succinate dehydrogenase
HUT06_RS36980	COG3976	FMN-binding domain protein
HUT06_RS37000	COG4106	trans-aconitate 2-methyltransferase activity
HUT06_RS37005	COG4608	Belongs to the ABC transporter superfamily
HUT06_RS37010	COG0444	Belongs to the ABC transporter superfamily
HUT06_RS37025	COG0747	negative chemotaxis
HUT06_RS37045	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS37050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS37070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT06_RS37090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT06_RS37095	COG0793	Belongs to the peptidase S41A family
HUT06_RS37105	COG2884	Cell division ATP-binding protein ftsE
HUT06_RS37120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT06_RS37130	COG2902	Dehydrogenase
HUT06_RS37150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT06_RS37160	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS37170	COG1011	Hydrolase
HUT06_RS37175	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS37180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT06_RS37185	COG1737	Transcriptional regulator
HUT06_RS37195	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT06_RS37205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT06_RS37210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT06_RS37225	COG1263	PTS System
HUT06_RS37225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT06_RS37235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUT06_RS37240	COG2188	Transcriptional regulator
HUT06_RS37245	COG1263	PTS System
HUT06_RS37255	COG0653	protein targeting
HUT06_RS37265	COG3214	Protein conserved in bacteria
HUT06_RS37270	COG2197	response regulator
HUT06_RS37275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT06_RS37280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUT06_RS37285	COG5401	PFAM Sporulation and spore germination
HUT06_RS37290	COG5002	protein histidine kinase activity
HUT06_RS37290	COG5000	phosphorelay sensor kinase activity
HUT06_RS37295	COG0745	RESPONSE REGULATOR receiver
HUT06_RS37315	COG0714	Associated with various cellular activities
HUT06_RS37340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT06_RS37360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT06_RS37365	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT06_RS37380	COG2197	response regulator
HUT06_RS37385	COG4585	Histidine kinase
HUT06_RS37395	COG2222	sugar isomerase
HUT06_RS37405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT06_RS37440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT06_RS37445	COG0778	Nitroreductase
HUT06_RS37445	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT06_RS37450	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT06_RS37460	COG0583	DNA-binding transcription factor activity
HUT06_RS37520	COG3385	transposase activity
HUT06_RS37530	COG0515	serine threonine protein kinase
HUT06_RS37530	COG2815	serine threonine protein kinase
HUT06_RS37545	COG2226	methyltransferase
HUT06_RS37555	COG3118	belongs to the thioredoxin family
HUT06_RS37560	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS37580	COG1316	TRANSCRIPTIONal
HUT06_RS37585	COG3594	Acyltransferase
HUT06_RS37590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT06_RS37605	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS37635	COG0438	transferase activity, transferring glycosyl groups
HUT06_RS37670	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS37675	COG3973	AAA domain
HUT06_RS37685	COG1215	transferase activity, transferring glycosyl groups
HUT06_RS37705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT06_RS37735	COG1316	TRANSCRIPTIONal
HUT06_RS37755	COG0738	Major facilitator superfamily
HUT06_RS37760	COG1349	DNA-binding transcription factor activity
HUT06_RS37805	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT06_RS37810	COG1832	CoA-binding protein
HUT06_RS37815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUT06_RS37830	COG2205	protein histidine kinase activity
HUT06_RS37835	COG0745	RESPONSE REGULATOR receiver
HUT06_RS37865	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT06_RS37875	COG1024	Enoyl-CoA hydratase
HUT06_RS37885	COG4941	Belongs to the sigma-70 factor family
HUT06_RS37890	COG3795	YCII-related domain
HUT06_RS37895	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUT06_RS37900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT06_RS37910	COG1432	Conserved Protein
HUT06_RS37990	COG1674	ftsk spoiiie
HUT06_RS38060	COG4770	biotin carboxylase activity
HUT06_RS38075	COG4585	Histidine kinase
HUT06_RS38080	COG2197	response regulator
HUT06_RS38110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT06_RS38120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT06_RS38160	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT06_RS38165	COG1476	TRANSCRIPTIONal
HUT06_RS38180	COG2018	Roadblock/LC7 domain
HUT06_RS38260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT06_RS38260	COG1473	amidohydrolase
HUT06_RS38265	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT06_RS38275	COG1295	ribonuclease BN
HUT06_RS38285	COG0180	Tryptophanyl-tRNA synthetase
HUT06_RS38290	COG1253	flavin adenine dinucleotide binding
HUT06_RS38295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT06_RS38300	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT06_RS38310	COG0326	Molecular chaperone. Has ATPase activity
HUT06_RS38370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT06_RS38375	COG2318	DinB family
HUT06_RS38380	COG0039	L-malate dehydrogenase activity
HUT06_RS38400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT06_RS38415	COG0138	bifunctional purine biosynthesis protein purh
HUT06_RS38440	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT06_RS38455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT06_RS38490	COG1461	Dihydroxyacetone kinase
HUT06_RS38495	COG2376	Dihydroxyacetone kinase
HUT06_RS38500	COG1957	nucleoside hydrolase
HUT06_RS38525	COG2197	response regulator
HUT06_RS38575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT06_RS38580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT06_RS38585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT06_RS38595	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
HUT06_RS38610	COG1090	epimerase
HUT06_RS38615	COG0450	alkyl hydroperoxide reductase
HUT06_RS38620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT06_RS38625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT06_RS38625	COG0519	Catalyzes the synthesis of GMP from XMP
HUT06_RS38650	COG1012	belongs to the aldehyde dehydrogenase family
HUT06_RS38660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT06_RS38665	COG0516	GMP reductase activity
HUT06_RS38685	COG1595	DNA-templated transcription, initiation
HUT06_RS38690	COG0459	protein refolding
HUT06_RS38695	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT06_RS38715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT06_RS38725	COG1214	PFAM Peptidase M22, glycoprotease
HUT06_RS38725	COG0456	acetyltransferase
HUT06_RS38735	COG0802	atpase or kinase
HUT06_RS38745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT06_RS38780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT06_RS38785	COG1072	(Pantothenic acid kinase))
HUT06_RS38795	COG3831	ATPase activity
HUT06_RS38805	COG4585	Histidine kinase
HUT06_RS38810	COG2197	response regulator
HUT06_RS38820	COG1131	(ABC) transporter
HUT06_RS38830	COG1131	(ABC) transporter
HUT06_RS38850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT06_RS38855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT06_RS38860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT06_RS38865	COG2340	Cysteine-rich secretory protein family
HUT06_RS38880	COG0101	tRNA pseudouridine synthase activity
HUT06_RS38885	COG0203	ribosomal protein L17
HUT06_RS38890	COG0202	RNA polymerase activity
HUT06_RS38895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT06_RS38900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT06_RS38905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUT06_RS38910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT06_RS38915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT06_RS38930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUT06_RS38945	COG0563	adenylate kinase activity
HUT06_RS38950	COG0201	protein transport
HUT06_RS38955	COG0200	Binds to the 23S rRNA
HUT06_RS38965	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT06_RS38970	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT06_RS38975	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT06_RS38980	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT06_RS38985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT06_RS38990	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT06_RS38995	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT06_RS39000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT06_RS39005	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT06_RS39010	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT06_RS39015	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT06_RS39020	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT06_RS39025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT06_RS39030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT06_RS39035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT06_RS39040	COG0089	rRNA binding
HUT06_RS39045	COG0088	Forms part of the polypeptide exit tunnel
HUT06_RS39050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT06_RS39055	COG0051	transcription antitermination factor activity, RNA binding
HUT06_RS39060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT06_RS39065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT06_RS39070	COG0049	tRNA binding
HUT06_RS39075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT06_RS39090	COG0667	Aldo Keto reductase
HUT06_RS39145	COG1595	DNA-templated transcription, initiation
HUT06_RS39170	COG2197	response regulator
HUT06_RS39250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT06_RS39260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT06_RS39265	COG0085	RNA polymerase activity
HUT06_RS39285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT06_RS39310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT06_RS39315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT06_RS39325	COG0222	ribosome binding
HUT06_RS39330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUT06_RS39365	COG1309	transcriptional regulator
HUT06_RS39375	COG0081	regulation of translation
HUT06_RS39380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT06_RS39390	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUT06_RS39400	COG0436	Aminotransferase
HUT06_RS39410	COG1595	DNA-templated transcription, initiation
HUT06_RS39420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT06_RS39430	COG1802	Transcriptional regulator
HUT06_RS39435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT06_RS39445	COG2030	dehydratase
HUT06_RS39450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT06_RS39465	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS39575	COG1674	ftsk spoiiie
HUT06_RS39600	COG1666	GTP binding
HUT06_RS39605	COG0501	Belongs to the peptidase M48B family
HUT06_RS39610	COG1007	ATP synthesis coupled electron transport
HUT06_RS39620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT06_RS39625	COG0713	ATP synthesis coupled electron transport
HUT06_RS39635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS39645	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT06_RS39650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS39655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS39660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS39675	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT06_RS39675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT06_RS39680	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT06_RS39755	COG2124	cytochrome p450
HUT06_RS39790	COG0583	DNA-binding transcription factor activity
HUT06_RS39795	COG2814	Major facilitator Superfamily
HUT06_RS39815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT06_RS39830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS39835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT06_RS39840	COG1034	ATP synthesis coupled electron transport
HUT06_RS39855	COG0649	NAD binding
HUT06_RS39860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS39865	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT06_RS39880	COG2226	methyltransferase
HUT06_RS39910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT06_RS39915	COG1333	cytochrome c biogenesis protein
HUT06_RS39920	COG0785	Cytochrome C biogenesis protein
HUT06_RS39925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT06_RS39930	COG0406	alpha-ribazole phosphatase activity
HUT06_RS39945	COG0697	spore germination
HUT06_RS39950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT06_RS39955	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT06_RS39960	COG0515	serine threonine protein kinase
HUT06_RS39960	COG2815	serine threonine protein kinase
HUT06_RS39970	COG0113	porphobilinogen synthase activity
HUT06_RS39975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT06_RS39975	COG1648	precorrin-2 dehydrogenase activity
HUT06_RS39980	COG0181	hydroxymethylbilane synthase activity
HUT06_RS39985	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT06_RS39990	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT06_RS40015	COG0560	Phosphoserine phosphatase
HUT06_RS40075	COG2267	carboxylic ester hydrolase activity
HUT06_RS40100	COG1595	DNA-templated transcription, initiation
HUT06_RS40130	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUT06_RS40150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUT06_RS40155	COG0506	proline dehydrogenase activity
HUT06_RS40160	COG1316	TRANSCRIPTIONal
HUT06_RS40180	COG1082	Xylose isomerase domain protein TIM barrel
HUT06_RS40185	COG0500	methyltransferase
HUT06_RS40195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUT06_RS40200	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUT06_RS40215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT06_RS40215	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HUT06_RS40225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT06_RS40255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT06_RS40270	COG1609	Transcriptional regulator
HUT06_RS40280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT06_RS40285	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT06_RS40295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT06_RS40300	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT06_RS40305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT06_RS40315	COG0577	efflux transmembrane transporter activity
HUT06_RS40320	COG1136	(ABC) transporter
HUT06_RS40330	COG2197	response regulator
HUT06_RS40335	COG4585	Histidine kinase
HUT06_RS40340	COG0617	tRNA 3'-terminal CCA addition
HUT06_RS40345	COG2124	cytochrome p450
HUT06_RS40370	COG0649	NAD binding
HUT06_RS40380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUT06_RS40385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUT06_RS40400	COG0302	gtp cyclohydrolase
HUT06_RS40415	COG0037	tRNA processing
HUT06_RS40425	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT06_RS40430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT06_RS40435	COG3883	PFAM NLP P60 protein
HUT06_RS40435	COG0791	NLP P60 protein
HUT06_RS40470	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT06_RS40480	COG3397	chitin binding
HUT06_RS40560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT06_RS40650	COG3848	Pyruvate phosphate dikinase
HUT06_RS40650	COG0574	Belongs to the PEP-utilizing enzyme family
HUT06_RS40690	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS40715	COG0028	Belongs to the TPP enzyme family
HUT06_RS40850	COG1309	transcriptional regulator
HUT06_RS40860	COG2267	carboxylic ester hydrolase activity
HUT06_RS40890	COG2267	carboxylic ester hydrolase activity
HUT06_RS40905	COG2318	DinB family
HUT06_RS40910	COG2226	methyltransferase
HUT06_RS40930	COG0167	dihydroorotate dehydrogenase activity
HUT06_RS40940	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT06_RS40985	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT06_RS41025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT06_RS41030	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT06_RS41040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT06_RS41050	COG4941	Belongs to the sigma-70 factor family
HUT06_RS41055	COG3795	YCII-related domain
HUT06_RS41095	COG0022	dehydrogenase e1 component
HUT06_RS41100	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT06_RS41195	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS41200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT06_RS41205	COG2076	Multidrug Resistance protein
HUT06_RS41220	COG4221	oxidoreductase activity
HUT06_RS41230	COG0604	alcohol dehydrogenase
HUT06_RS41230	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS41230	COG3321	synthase
HUT06_RS41285	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS41290	COG3386	PFAM SMP-30 Gluconolaconase
HUT06_RS41300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT06_RS41310	COG4941	Belongs to the sigma-70 factor family
HUT06_RS41320	COG2409	Drug exporters of the RND superfamily
HUT06_RS41325	COG1595	DNA-templated transcription, initiation
HUT06_RS41365	COG0784	Response regulator, receiver
HUT06_RS41370	COG4251	negative regulation of phosphorylation
HUT06_RS41390	COG0577	efflux transmembrane transporter activity
HUT06_RS41390	COG1136	(ABC) transporter
HUT06_RS41395	COG1136	(ABC) transporter
HUT06_RS41395	COG0577	efflux transmembrane transporter activity
HUT06_RS41400	COG2205	protein histidine kinase activity
HUT06_RS41405	COG0745	RESPONSE REGULATOR receiver
HUT06_RS41420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUT06_RS41480	COG0577	efflux transmembrane transporter activity
HUT06_RS41480	COG1136	(ABC) transporter
HUT06_RS41495	COG2197	response regulator
HUT06_RS41525	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT06_RS41545	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT06_RS41585	COG2197	response regulator
HUT06_RS41605	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS41655	COG1846	Transcriptional regulator
HUT06_RS41675	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS41685	COG1733	regulation of RNA biosynthetic process
HUT06_RS41695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUT06_RS41710	COG1960	acyl-CoA dehydrogenase activity
HUT06_RS41730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT06_RS41735	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT06_RS41740	COG2205	protein histidine kinase activity
HUT06_RS41765	COG3321	synthase
HUT06_RS41765	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS41765	COG0604	alcohol dehydrogenase
HUT06_RS41800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT06_RS41805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT06_RS41805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT06_RS41830	COG2409	Drug exporters of the RND superfamily
HUT06_RS41835	COG1309	transcriptional regulator
HUT06_RS41845	COG3226	Transcriptional regulator
HUT06_RS41875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT06_RS41880	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS41885	COG2197	response regulator
HUT06_RS41905	COG2409	Drug exporters of the RND superfamily
HUT06_RS41915	COG2197	response regulator
HUT06_RS41925	COG1024	Enoyl-CoA hydratase
HUT06_RS41935	COG0515	serine threonine protein kinase
HUT06_RS41935	COG2815	serine threonine protein kinase
HUT06_RS41945	COG1595	DNA-templated transcription, initiation
HUT06_RS41990	COG2353	YceI-like domain
HUT06_RS41995	COG2205	protein histidine kinase activity
HUT06_RS42005	COG0745	RESPONSE REGULATOR receiver
HUT06_RS42010	COG2205	protein histidine kinase activity
HUT06_RS42025	COG2186	Transcriptional regulator
HUT06_RS42050	COG1595	DNA-templated transcription, initiation
HUT06_RS42075	COG1280	lysine exporter protein (LysE YggA)
HUT06_RS42080	COG1522	sequence-specific DNA binding
HUT06_RS42105	COG4585	Histidine kinase
HUT06_RS42160	COG2814	Major facilitator Superfamily
HUT06_RS42170	COG1846	Transcriptional regulator
HUT06_RS42185	COG1846	Transcriptional regulator
HUT06_RS42200	COG0477	Major facilitator Superfamily
HUT06_RS42205	COG1819	glycosyl
HUT06_RS42210	COG2409	Drug exporters of the RND superfamily
HUT06_RS42215	COG0318	PFAM AMP-dependent synthetase and ligase
HUT06_RS42240	COG3339	Conserved Protein
HUT06_RS42250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUT06_RS42270	COG1309	transcriptional regulator
HUT06_RS42305	COG1940	carbohydrate kinase activity
HUT06_RS42340	COG0662	Cupin 2, conserved barrel domain protein
HUT06_RS42355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT06_RS42360	COG2207	Transcriptional regulator
HUT06_RS42380	COG0243	molybdopterin cofactor binding
HUT06_RS42400	COG1119	ATPase activity
HUT06_RS42420	COG0675	Transposase, IS605 OrfB family
HUT06_RS42430	COG2197	response regulator
HUT06_RS42450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT06_RS42455	COG3830	Belongs to the UPF0237 family
HUT06_RS42455	COG0560	Phosphoserine phosphatase
HUT06_RS42475	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT06_RS42480	COG2172	sigma factor antagonist activity
HUT06_RS42485	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT06_RS42490	COG1205	dead DEAH box helicase
HUT06_RS42490	COG1111	helicase
HUT06_RS42505	COG0488	(ABC) transporter
HUT06_RS42565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT06_RS42570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT06_RS42580	COG0596	Alpha beta hydrolase
HUT06_RS42590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT06_RS42615	COG1028	Short-chain dehydrogenase reductase Sdr
HUT06_RS42635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT06_RS42640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT06_RS42665	COG2130	NADP-dependent
HUT06_RS42680	COG0003	Pfam Anion-transporting ATPase
HUT06_RS42700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT06_RS42710	COG1408	metallophosphoesterase
HUT06_RS42715	COG2226	methyltransferase
HUT06_RS42725	COG3547	Transposase (IS116 IS110 IS902 family)
HUT06_RS42760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT06_RS42845	COG4974	Belongs to the 'phage' integrase family
HUT06_RS42885	COG1595	DNA-templated transcription, initiation
HUT06_RS42890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT06_RS42955	COG0651	ATP synthesis coupled electron transport
HUT06_RS42995	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HUT06_RS43005	COG0596	Alpha beta hydrolase
HUT06_RS43010	COG3903	Transcriptional regulator
HUT06_RS43010	COG3629	intracellular signal transduction
HUT06_RS43015	COG0753	catalase activity
HUT06_RS43040	COG0583	DNA-binding transcription factor activity
HUT06_RS43075	COG1309	transcriptional regulator
HUT06_RS43105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT06_RS43110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT06_RS43115	COG0110	maltose O-acetyltransferase activity
HUT06_RS43155	COG2807	transmembrane transport
HUT06_RS43160	COG2186	Transcriptional regulator
HUT06_RS43185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUT06_RS43210	COG0590	tRNA wobble adenosine to inosine editing
HUT06_RS43240	COG0592	DNA-directed DNA polymerase activity
HUT06_RS43285	COG2264	protein methyltransferase activity
HUT06_RS43310	COG1846	Transcriptional regulator
HUT06_RS43335	COG2409	Drug exporters of the RND superfamily
HUT06_RS43375	COG0305	Participates in initiation and elongation during chromosome replication
HUT06_RS43395	COG0359	binds to the 23S rRNA
HUT06_RS43400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT06_RS43405	COG0629	single-stranded DNA binding
HUT06_RS43410	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT06_RS43425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HUT06_RS43440	COG0789	Transcriptional regulator
HUT06_RS43450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT06_RS43455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT06_RS43470	COG4166	transmembrane transport
HUT06_RS43490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT06_RS43495	COG0617	tRNA 3'-terminal CCA addition
HUT06_RS43515	COG2815	serine threonine protein kinase
HUT06_RS43515	COG0515	serine threonine protein kinase
HUT06_RS43520	COG1595	DNA-templated transcription, initiation
HUT06_RS43540	COG3118	belongs to the thioredoxin family
HUT06_RS43550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT06_RS43555	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT06_RS43570	COG1192	Involved in chromosome partitioning
HUT06_RS43575	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT06_RS43595	COG0706	membrane insertase activity
HUT06_RS43600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT06_RS43605	COG0594	ribonuclease P activity
HUT06_RS43610	COG0230	Belongs to the bacterial ribosomal protein bL34 family