locus-tag	class	description
ADJ76_RS00030	COG0300	oxidoreductase activity
ADJ76_RS00035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADJ76_RS00045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADJ76_RS00050	COG0191	fructose-bisphosphate aldolase activity
ADJ76_RS00080	COG3842	ATPase activity
ADJ76_RS00085	COG0515	serine threonine protein kinase
ADJ76_RS00085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADJ76_RS00100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADJ76_RS00110	COG0459	protein refolding
ADJ76_RS00125	COG2205	protein histidine kinase activity
ADJ76_RS00130	COG0745	RESPONSE REGULATOR receiver
ADJ76_RS00150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADJ76_RS00155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ADJ76_RS00170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADJ76_RS00175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADJ76_RS00185	COG1842	Phage shock protein A
ADJ76_RS00195	COG1278	Cold shock
ADJ76_RS00205	COG2252	PERMEase
ADJ76_RS00215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ADJ76_RS00250	COG1970	mechanosensitive ion channel activity
ADJ76_RS00255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADJ76_RS00260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADJ76_RS00300	COG0085	RNA polymerase activity
ADJ76_RS00305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADJ76_RS00310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADJ76_RS00315	COG0049	tRNA binding
ADJ76_RS00325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADJ76_RS00330	COG0051	transcription antitermination factor activity, RNA binding
ADJ76_RS00335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADJ76_RS00340	COG0088	Forms part of the polypeptide exit tunnel
ADJ76_RS00345	COG0089	rRNA binding
ADJ76_RS00350	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADJ76_RS00355	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADJ76_RS00360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADJ76_RS00365	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADJ76_RS00370	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADJ76_RS00375	COG0255	Belongs to the universal ribosomal protein uL29 family
ADJ76_RS00380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADJ76_RS00385	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADJ76_RS00390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADJ76_RS00395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADJ76_RS00400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADJ76_RS00405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADJ76_RS00410	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADJ76_RS00420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADJ76_RS00425	COG1841	ribosomal large subunit assembly
ADJ76_RS00430	COG0200	Binds to the 23S rRNA
ADJ76_RS00440	COG0563	adenylate kinase activity
ADJ76_RS00445	COG0024	Methionine aminopeptidase
ADJ76_RS00450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADJ76_RS00455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADJ76_RS00460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADJ76_RS00465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADJ76_RS00470	COG0202	RNA polymerase activity
ADJ76_RS00475	COG0203	ribosomal protein L17
ADJ76_RS00480	COG0366	Alpha amylase catalytic
ADJ76_RS00490	COG0101	tRNA pseudouridine synthase activity
ADJ76_RS00495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADJ76_RS00500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADJ76_RS00535	COG0395	ABC-type sugar transport system, permease component
ADJ76_RS00545	COG1072	(Pantothenic acid kinase))
ADJ76_RS00550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADJ76_RS00555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADJ76_RS00555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADJ76_RS00560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADJ76_RS00565	COG0802	atpase or kinase
ADJ76_RS00575	COG0456	acetyltransferase
ADJ76_RS00585	COG1053	succinate dehydrogenase
ADJ76_RS00590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADJ76_RS00595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADJ76_RS00605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ADJ76_RS00610	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ADJ76_RS00620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADJ76_RS00630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADJ76_RS00630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADJ76_RS00670	COG0516	GMP reductase activity
ADJ76_RS00690	COG3845	ABC transporter
ADJ76_RS00695	COG4603	Belongs to the binding-protein-dependent transport system permease family
ADJ76_RS00700	COG1079	Belongs to the binding-protein-dependent transport system permease family
ADJ76_RS00715	COG2390	Transcriptional regulator
ADJ76_RS00720	COG0813	purine-nucleoside phosphorylase activity
ADJ76_RS00730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADJ76_RS00735	COG2226	methyltransferase
ADJ76_RS00775	COG1056	cytidyltransferase-related domain
ADJ76_RS00775	COG1051	belongs to the nudix hydrolase family
ADJ76_RS00790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADJ76_RS00795	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADJ76_RS00800	COG0857	belongs to the CobB CobQ family
ADJ76_RS00800	COG0280	phosphate acetyltransferase
ADJ76_RS00810	COG0205	6-phosphofructokinase activity
ADJ76_RS00815	COG0166	Belongs to the GPI family
ADJ76_RS00850	COG1131	(ABC) transporter
ADJ76_RS00875	COG1960	acyl-CoA dehydrogenase activity
ADJ76_RS00890	COG2030	dehydratase
ADJ76_RS00895	COG2271	Major facilitator Superfamily
ADJ76_RS00900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADJ76_RS00910	COG2086	electron transfer activity
ADJ76_RS00915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADJ76_RS00920	COG0644	oxidoreductase
ADJ76_RS00935	COG0039	L-malate dehydrogenase activity
ADJ76_RS00950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADJ76_RS00950	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADJ76_RS01000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADJ76_RS01005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADJ76_RS01010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADJ76_RS01025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADJ76_RS01035	COG0193	aminoacyl-tRNA hydrolase activity
ADJ76_RS01050	COG0148	phosphopyruvate hydratase activity
ADJ76_RS01080	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADJ76_RS01085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADJ76_RS01095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADJ76_RS01105	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADJ76_RS01115	COG1722	exodeoxyribonuclease VII activity
ADJ76_RS01120	COG1570	exodeoxyribonuclease VII activity
ADJ76_RS01125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADJ76_RS01130	COG0012	GTP binding
ADJ76_RS01170	COG1401	restriction endodeoxyribonuclease activity
ADJ76_RS01175	COG4268	DNA restriction-modification system
ADJ76_RS01200	COG1653	transport
ADJ76_RS01205	COG1175	transmembrane transport
ADJ76_RS01210	COG0395	ABC-type sugar transport system, permease component
ADJ76_RS01235	COG0789	Transcriptional regulator
ADJ76_RS01260	COG1217	gtp-binding protein TYPA
ADJ76_RS01285	COG0424	maF-like protein
ADJ76_RS01295	COG0745	RESPONSE REGULATOR receiver
ADJ76_RS01300	COG2205	protein histidine kinase activity
ADJ76_RS01305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADJ76_RS01310	COG1316	TRANSCRIPTIONal
ADJ76_RS01315	COG1316	TRANSCRIPTIONal
ADJ76_RS01345	COG0438	transferase activity, transferring glycosyl groups
ADJ76_RS01360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADJ76_RS01370	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADJ76_RS01385	COG0463	Glycosyl transferase, family 2
ADJ76_RS01430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADJ76_RS01435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADJ76_RS01440	COG2884	Cell division ATP-binding protein ftsE
ADJ76_RS01455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADJ76_RS01465	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADJ76_RS01470	COG1937	Protein conserved in bacteria
ADJ76_RS01510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADJ76_RS01520	COG4166	transmembrane transport
ADJ76_RS01525	COG1940	carbohydrate kinase activity
ADJ76_RS01535	COG1940	carbohydrate kinase activity
ADJ76_RS01540	COG3142	Participates in the control of copper homeostasis
ADJ76_RS01545	COG0363	glucosamine-6-phosphate deaminase activity
ADJ76_RS01575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADJ76_RS01585	COG0583	DNA-binding transcription factor activity
ADJ76_RS01595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADJ76_RS01600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADJ76_RS01625	COG3480	Lon protease (S16) C-terminal proteolytic domain
ADJ76_RS01635	COG1615	UPF0182 protein
ADJ76_RS01650	COG1285	pathogenesis
ADJ76_RS01655	COG0833	amino acid
ADJ76_RS01665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADJ76_RS01665	COG3253	May function as heme-dependent peroxidase
ADJ76_RS01695	COG1309	transcriptional regulator
ADJ76_RS01705	COG0577	efflux transmembrane transporter activity
ADJ76_RS01705	COG1136	(ABC) transporter
ADJ76_RS01710	COG0833	amino acid
ADJ76_RS01730	COG0114	fumarate hydratase activity
ADJ76_RS01745	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ADJ76_RS01775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADJ76_RS01780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADJ76_RS01785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADJ76_RS01790	COG0154	amidase activity
ADJ76_RS01795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADJ76_RS01825	COG0569	domain protein
ADJ76_RS01825	COG2985	domain, Protein
ADJ76_RS01840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADJ76_RS01855	COG0779	Required for maturation of 30S ribosomal subunits
ADJ76_RS01860	COG0195	Participates in both transcription termination and antitermination
ADJ76_RS01870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADJ76_RS01875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADJ76_RS01880	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADJ76_RS01885	COG0196	riboflavin kinase activity
ADJ76_RS01890	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADJ76_RS01895	COG1185	polyribonucleotide nucleotidyltransferase activity
ADJ76_RS01900	COG0612	Peptidase, M16
ADJ76_RS01920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADJ76_RS01930	COG1674	ftsk spoiiie
ADJ76_RS01950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADJ76_RS01955	COG2137	regulation of response to DNA damage stimulus
ADJ76_RS01960	COG1058	Belongs to the CinA family
ADJ76_RS01960	COG1546	Belongs to the CinA family
ADJ76_RS01965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADJ76_RS01980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADJ76_RS01985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADJ76_RS01990	COG2813	Specifically methylates the guanine in position
ADJ76_RS01995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADJ76_RS02010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADJ76_RS02020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADJ76_RS02025	COG0318	PFAM AMP-dependent synthetase and ligase
ADJ76_RS02050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADJ76_RS02060	COG2001	Belongs to the MraZ family
ADJ76_RS02065	COG0275	rRNA processing
ADJ76_RS02075	COG0768	penicillin binding
ADJ76_RS02080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ADJ76_RS02085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADJ76_RS02090	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADJ76_RS02100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADJ76_RS02105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADJ76_RS02115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADJ76_RS02125	COG1799	cell septum assembly
ADJ76_RS02135	COG3599	regulation of cell shape
ADJ76_RS02140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADJ76_RS02175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADJ76_RS02180	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADJ76_RS02185	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADJ76_RS02190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADJ76_RS02205	COG1309	transcriptional regulator
ADJ76_RS02210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADJ76_RS02220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADJ76_RS02225	COG0742	ribosomal rna small subunit methyltransferase
ADJ76_RS02245	COG0571	ribonuclease III activity
ADJ76_RS02265	COG1132	(ABC) transporter
ADJ76_RS02270	COG4988	ABC transporter
ADJ76_RS02275	COG1294	oxidase, subunit
ADJ76_RS02280	COG1271	oxidase subunit
ADJ76_RS02285	COG1530	ribonuclease E activity
ADJ76_RS02290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADJ76_RS02295	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADJ76_RS02300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADJ76_RS02305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADJ76_RS02310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADJ76_RS02315	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADJ76_RS02350	COG3590	peptidase
ADJ76_RS02355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADJ76_RS02360	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ADJ76_RS02365	COG0247	lactate metabolic process
ADJ76_RS02375	COG0641	radical SAM
ADJ76_RS02380	COG3119	arylsulfatase activity
ADJ76_RS02390	COG0701	Predicted permease
ADJ76_RS02405	COG0789	Transcriptional regulator
ADJ76_RS02410	COG0285	dihydrofolate synthase activity
ADJ76_RS02415	COG2376	Dihydroxyacetone kinase
ADJ76_RS02420	COG1461	Dihydroxyacetone kinase
ADJ76_RS02425	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ADJ76_RS02430	COG0105	UTP biosynthetic process
ADJ76_RS02440	COG3547	Transposase (IS116 IS110 IS902 family)
ADJ76_RS02445	COG3547	Transposase (IS116 IS110 IS902 family)
ADJ76_RS02455	COG0187	DNA topoisomerase II activity
ADJ76_RS02470	COG2814	Major facilitator Superfamily
ADJ76_RS02480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADJ76_RS02525	COG0569	domain protein
ADJ76_RS02530	COG0531	amino acid
ADJ76_RS02535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADJ76_RS02540	COG0038	chloride channel
ADJ76_RS02615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADJ76_RS02625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADJ76_RS02635	COG0438	transferase activity, transferring glycosyl groups
ADJ76_RS02655	COG1051	belongs to the nudix hydrolase family
ADJ76_RS02660	COG0560	Phosphoserine phosphatase
ADJ76_RS02670	COG0297	glycogen (starch) synthase activity
ADJ76_RS02675	COG1119	ATPase activity
ADJ76_RS02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ADJ76_RS02710	COG0588	phosphoglycerate mutase activity
ADJ76_RS02715	COG0217	transcriptional regulatory protein
ADJ76_RS02720	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ADJ76_RS02730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ADJ76_RS02735	COG0632	four-way junction helicase activity
ADJ76_RS02740	COG2255	four-way junction helicase activity
ADJ76_RS02750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADJ76_RS02755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADJ76_RS02760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADJ76_RS02765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADJ76_RS02770	COG1196	nuclear chromosome segregation
ADJ76_RS02775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADJ76_RS02780	COG0124	histidyl-tRNA synthetase
ADJ76_RS02785	COG1162	GTPase activity
ADJ76_RS02800	COG0477	Major facilitator Superfamily
ADJ76_RS02810	COG0009	L-threonylcarbamoyladenylate synthase
ADJ76_RS02830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADJ76_RS02835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADJ76_RS02840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADJ76_RS02870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADJ76_RS02875	COG0469	pyruvate kinase activity
ADJ76_RS02895	COG2050	protein possibly involved in aromatic compounds catabolism
ADJ76_RS02905	COG0539	negative regulation of cytoplasmic translation
ADJ76_RS02910	COG1114	Component of the transport system for branched-chain amino acids
ADJ76_RS02915	COG0237	dephospho-CoA kinase activity
ADJ76_RS02920	COG0556	nucleotide-excision repair
ADJ76_RS02935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ADJ76_RS02945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADJ76_RS02955	COG1022	Amp-dependent synthetase and ligase
ADJ76_RS02970	COG0322	excinuclease ABC activity
ADJ76_RS02980	COG1660	Displays ATPase and GTPase activities
ADJ76_RS02990	COG1481	regulation of sporulation
ADJ76_RS02995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADJ76_RS03000	COG0126	phosphoglycerate kinase activity
ADJ76_RS03005	COG0149	triose-phosphate isomerase activity
ADJ76_RS03015	COG0363	glucosamine-6-phosphate deaminase activity
ADJ76_RS03050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADJ76_RS03065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADJ76_RS03085	COG0519	Catalyzes the synthesis of GMP from XMP
ADJ76_RS03090	COG1160	GTP binding
ADJ76_RS03095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADJ76_RS03120	COG1716	ATPase activity
ADJ76_RS03135	COG0443	Heat shock 70 kDa protein
ADJ76_RS03150	COG1216	Glycosyl transferase, family 2
ADJ76_RS03175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ADJ76_RS03180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADJ76_RS03185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADJ76_RS03195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADJ76_RS03210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADJ76_RS03220	COG1758	RNA polymerase activity
ADJ76_RS03225	COG0194	GDP metabolic process
ADJ76_RS03235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ADJ76_RS03240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADJ76_RS03245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADJ76_RS03250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADJ76_RS03255	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADJ76_RS03260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADJ76_RS03265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADJ76_RS03275	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ADJ76_RS03285	COG4122	O-methyltransferase activity
ADJ76_RS03290	COG1222	aaa ATPase
ADJ76_RS03305	COG0656	L-ascorbic acid biosynthetic process
ADJ76_RS03355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADJ76_RS03370	COG1881	PFAM PEBP family protein
ADJ76_RS03375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ADJ76_RS03385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADJ76_RS03390	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ76_RS03410	COG0765	amino acid transport
ADJ76_RS03415	COG1126	abc transporter atp-binding protein
ADJ76_RS03420	COG0488	(ABC) transporter
ADJ76_RS03430	COG0343	queuine tRNA-ribosyltransferase activity
ADJ76_RS03440	COG0318	PFAM AMP-dependent synthetase and ligase
ADJ76_RS03445	COG2151	metal-sulfur cluster biosynthetic enzyme
ADJ76_RS03460	COG0396	ATPase activity
ADJ76_RS03470	COG0719	Fe-S assembly protein
ADJ76_RS03500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADJ76_RS03515	COG0647	UMP catabolic process
ADJ76_RS03540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADJ76_RS03545	COG0165	Argininosuccinate lyase
ADJ76_RS03555	COG0137	argininosuccinate synthase activity
ADJ76_RS03560	COG1438	arginine binding
ADJ76_RS03580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADJ76_RS03590	COG1940	carbohydrate kinase activity
ADJ76_RS03605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADJ76_RS03610	COG0321	lipoyl(octanoyl) transferase activity
ADJ76_RS03615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADJ76_RS03620	COG1252	NADH dehydrogenase
ADJ76_RS03635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADJ76_RS03640	COG1027	Aspartate ammonia-lyase
ADJ76_RS03660	COG0442	prolyl-tRNA aminoacylation
ADJ76_RS03675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADJ76_RS03680	COG0750	zinc metalloprotease
ADJ76_RS03685	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADJ76_RS03700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADJ76_RS03710	COG0233	cytoplasmic translational termination
ADJ76_RS03720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADJ76_RS03725	COG0052	Belongs to the universal ribosomal protein uS2 family
ADJ76_RS03750	COG0792	nuclease activity
ADJ76_RS03760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADJ76_RS03765	COG0681	Belongs to the peptidase S26 family
ADJ76_RS03770	COG0335	large ribosomal subunit rRNA binding
ADJ76_RS03780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADJ76_RS03785	COG1837	Belongs to the UPF0109 family
ADJ76_RS03790	COG0228	four-way junction DNA binding
ADJ76_RS03815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADJ76_RS03820	COG0142	geranyltranstransferase activity
ADJ76_RS03830	COG0515	serine threonine protein kinase
ADJ76_RS03830	COG2815	serine threonine protein kinase
ADJ76_RS03835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ADJ76_RS03860	COG0545	Peptidyl-prolyl cis-trans isomerase
ADJ76_RS03875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADJ76_RS03905	COG0733	neurotransmitter:sodium symporter activity
ADJ76_RS03915	COG1216	Glycosyl transferase, family 2
ADJ76_RS03930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ76_RS03930	COG1263	PTS System
ADJ76_RS03960	COG4770	biotin carboxylase activity
ADJ76_RS03965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADJ76_RS03970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADJ76_RS03970	COG3321	synthase
ADJ76_RS03970	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ADJ76_RS03975	COG0736	holo-[acyl-carrier-protein] synthase activity
ADJ76_RS03985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ADJ76_RS04010	COG1739	Uncharacterized protein family UPF0029
ADJ76_RS04015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADJ76_RS04020	COG1045	serine acetyltransferase
ADJ76_RS04035	COG0495	leucyl-tRNA aminoacylation
ADJ76_RS04045	COG1321	iron dependent repressor
ADJ76_RS04080	COG0482	sulfurtransferase activity
ADJ76_RS04090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADJ76_RS04095	COG2086	electron transfer activity
ADJ76_RS04105	COG0180	Tryptophanyl-tRNA synthetase
ADJ76_RS04115	COG0366	Alpha amylase catalytic
ADJ76_RS04120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ADJ76_RS04140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ADJ76_RS04150	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ADJ76_RS04165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADJ76_RS04170	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADJ76_RS04175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADJ76_RS04180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADJ76_RS04185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADJ76_RS04195	COG0356	it plays a direct role in the translocation of protons across the membrane
ADJ76_RS04205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADJ76_RS04210	COG0009	L-threonylcarbamoyladenylate synthase
ADJ76_RS04220	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADJ76_RS04225	COG0254	rRNA binding
ADJ76_RS04235	COG0083	homoserine kinase activity
ADJ76_RS04240	COG0460	homoserine dehydrogenase
ADJ76_RS04245	COG1882	Formate acetyltransferase
ADJ76_RS04260	COG0242	peptide deformylase activity
ADJ76_RS04265	COG0110	maltose O-acetyltransferase activity
ADJ76_RS04270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ADJ76_RS04280	COG2017	converts alpha-aldose to the beta-anomer
ADJ76_RS04290	COG0484	heat shock protein binding
ADJ76_RS04295	COG1420	regulation of RNA biosynthetic process
ADJ76_RS04320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ADJ76_RS04325	COG0481	GTPase activity
ADJ76_RS04340	COG0268	Binds directly to 16S ribosomal RNA
ADJ76_RS04345	COG1132	(ABC) transporter
ADJ76_RS04350	COG1132	(ABC) transporter
ADJ76_RS04370	COG0433	COG0433 Predicted ATPase
ADJ76_RS04375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADJ76_RS04380	COG2056	Na+-H+ antiporter family
ADJ76_RS04385	COG2197	response regulator
ADJ76_RS04390	COG1288	antiporter activity
ADJ76_RS04395	COG0549	Belongs to the carbamate kinase family
ADJ76_RS04400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADJ76_RS04425	COG1022	Amp-dependent synthetase and ligase
ADJ76_RS04430	COG0577	efflux transmembrane transporter activity
ADJ76_RS04435	COG0577	efflux transmembrane transporter activity
ADJ76_RS04435	COG1136	(ABC) transporter
ADJ76_RS04450	COG1605	Chorismate mutase
ADJ76_RS04450	COG0287	Prephenate dehydrogenase
ADJ76_RS04455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADJ76_RS04460	COG0740	serine-type endopeptidase activity
ADJ76_RS04465	COG0740	serine-type endopeptidase activity
ADJ76_RS04470	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADJ76_RS04490	COG1309	transcriptional regulator
ADJ76_RS04495	COG2375	cellular response to nickel ion
ADJ76_RS04495	COG1132	(ABC) transporter
ADJ76_RS04500	COG1132	(ABC) transporter
ADJ76_RS04515	COG1129	ABC transporter
ADJ76_RS04530	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADJ76_RS04535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADJ76_RS04550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADJ76_RS04575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADJ76_RS04600	COG1115	amino acid carrier protein
ADJ76_RS04610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADJ76_RS04620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADJ76_RS04625	COG3304	Inner membrane component domain
ADJ76_RS04635	COG0095	Lipoate-protein ligase
ADJ76_RS04640	COG0129	dihydroxy-acid dehydratase activity
ADJ76_RS04645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADJ76_RS04645	COG0519	Catalyzes the synthesis of GMP from XMP
ADJ76_RS04660	COG1132	(ABC) transporter
ADJ76_RS04665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADJ76_RS04685	COG0358	DNA primase activity
ADJ76_RS04700	COG0710	3-dehydroquinate dehydratase activity
ADJ76_RS04705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADJ76_RS04710	COG0423	glycine-tRNA ligase activity
ADJ76_RS04720	COG1131	(ABC) transporter
ADJ76_RS04730	COG3833	ABC-type maltose transport systems, permease component
ADJ76_RS04735	COG1175	transmembrane transport
ADJ76_RS04740	COG2182	Extracellular solute-binding protein
ADJ76_RS04755	COG1121	(ABC) transporter
ADJ76_RS04775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADJ76_RS04780	COG1381	Involved in DNA repair and RecF pathway recombination
ADJ76_RS04795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADJ76_RS04800	COG1620	l-lactate permease
ADJ76_RS04840	COG1139	Iron-sulfur cluster binding protein
ADJ76_RS04845	COG1556	Lactate utilization protein
ADJ76_RS04850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADJ76_RS04855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADJ76_RS04865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADJ76_RS04875	COG1643	Atp-dependent helicase
ADJ76_RS04885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADJ76_RS04930	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ADJ76_RS04965	COG0018	arginyl-trna synthetase
ADJ76_RS05025	COG2197	response regulator
ADJ76_RS05030	COG4585	Histidine kinase
ADJ76_RS05035	COG1131	(ABC) transporter
ADJ76_RS05050	COG0584	glycerophosphoryl diester phosphodiesterase
ADJ76_RS05055	COG0739	heme binding
ADJ76_RS05065	COG1253	flavin adenine dinucleotide binding
ADJ76_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ76_RS05070	COG0567	Dehydrogenase, E1 component
ADJ76_RS05100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADJ76_RS05105	COG1162	GTPase activity
ADJ76_RS05125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADJ76_RS05125	COG0519	Catalyzes the synthesis of GMP from XMP
ADJ76_RS05130	COG0420	3'-5' exonuclease activity
ADJ76_RS05135	COG0419	ATPase involved in DNA repair
ADJ76_RS05175	COG0653	protein targeting
ADJ76_RS05180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADJ76_RS05195	COG5000	phosphorelay sensor kinase activity
ADJ76_RS05195	COG5002	protein histidine kinase activity
ADJ76_RS05200	COG0745	RESPONSE REGULATOR receiver
ADJ76_RS05220	COG0714	Associated with various cellular activities
ADJ76_RS05225	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ADJ76_RS05275	COG1088	dTDP-glucose 4,6-dehydratase activity
ADJ76_RS05330	COG0697	spore germination
ADJ76_RS05335	COG3475	LICD family
ADJ76_RS05340	COG3475	LICD family
ADJ76_RS05345	COG3475	LICD family
ADJ76_RS05355	COG0438	transferase activity, transferring glycosyl groups
ADJ76_RS05360	COG3475	LICD family
ADJ76_RS05375	COG0395	ABC-type sugar transport system, permease component
ADJ76_RS05430	COG1131	(ABC) transporter
ADJ76_RS05440	COG0058	SHG alpha-glucan phosphorylase activity
ADJ76_RS05450	COG2095	MarC family integral membrane protein
ADJ76_RS05455	COG0613	PHP domain protein
ADJ76_RS05460	COG1113	amino acid transport
ADJ76_RS05465	COG0252	asparaginase activity
ADJ76_RS05470	COG0006	proline dipeptidase activity
ADJ76_RS05480	COG2239	Acts as a magnesium transporter
ADJ76_RS05500	COG1611	Belongs to the LOG family
ADJ76_RS05520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADJ76_RS05530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADJ76_RS05540	COG1309	transcriptional regulator
ADJ76_RS05590	COG0488	(ABC) transporter
ADJ76_RS05595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADJ76_RS05600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADJ76_RS05610	COG3583	domain protein
ADJ76_RS05615	COG0084	hydrolase, TatD family'
ADJ76_RS05625	COG0577	efflux transmembrane transporter activity
ADJ76_RS05625	COG1136	(ABC) transporter
ADJ76_RS05635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADJ76_RS05640	COG3949	Membrane
ADJ76_RS05655	COG2264	protein methyltransferase activity
ADJ76_RS05660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADJ76_RS05665	COG1573	uracil-dna glycosylase
ADJ76_RS05675	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADJ76_RS05680	COG1131	(ABC) transporter
ADJ76_RS05720	COG2323	membrane
ADJ76_RS05745	COG0519	Catalyzes the synthesis of GMP from XMP
ADJ76_RS05745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADJ76_RS05750	COG1268	BioY protein
ADJ76_RS05765	COG0045	succinate-CoA ligase (ADP-forming) activity
ADJ76_RS05775	COG4868	Belongs to the UPF0371 family
ADJ76_RS05780	COG2197	response regulator
ADJ76_RS05800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADJ76_RS05810	COG1609	Transcriptional regulator
ADJ76_RS05815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ76_RS05815	COG2190	(PTS) system
ADJ76_RS05815	COG1263	PTS System
ADJ76_RS05825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADJ76_RS05830	COG1335	isochorismatase
ADJ76_RS05865	COG0431	NADPH-dependent FMN reductase
ADJ76_RS05885	COG1115	amino acid carrier protein
ADJ76_RS05890	COG1063	alcohol dehydrogenase
ADJ76_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ76_RS05920	COG1349	DNA-binding transcription factor activity
ADJ76_RS05930	COG1609	Transcriptional regulator
ADJ76_RS05940	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ADJ76_RS05950	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ76_RS05955	COG1129	ABC transporter
ADJ76_RS05970	COG0789	Transcriptional regulator
ADJ76_RS05975	COG0222	ribosome binding
ADJ76_RS05985	COG1132	(ABC) transporter
ADJ76_RS05990	COG1132	(ABC) transporter
ADJ76_RS05990	COG2375	cellular response to nickel ion
ADJ76_RS05995	COG1129	ABC transporter
ADJ76_RS06010	COG0081	regulation of translation
ADJ76_RS06015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADJ76_RS06025	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADJ76_RS06035	COG0436	Aminotransferase
ADJ76_RS06045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ADJ76_RS06050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADJ76_RS06055	COG0738	Major facilitator superfamily
ADJ76_RS06060	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ADJ76_RS06070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADJ76_RS06075	COG4608	Belongs to the ABC transporter superfamily
ADJ76_RS06085	COG0601	transmembrane transport
ADJ76_RS06090	COG0747	negative chemotaxis
ADJ76_RS06105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADJ76_RS06125	COG1666	GTP binding
ADJ76_RS06130	COG0501	Belongs to the peptidase M48B family
ADJ76_RS06140	COG0142	geranyltranstransferase activity
ADJ76_RS06145	COG1007	ATP synthesis coupled electron transport
ADJ76_RS06155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADJ76_RS06160	COG0713	ATP synthesis coupled electron transport
ADJ76_RS06170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADJ76_RS06180	COG1034	ATP synthesis coupled electron transport
ADJ76_RS06185	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ADJ76_RS06195	COG0649	NAD binding
ADJ76_RS06200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADJ76_RS06205	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADJ76_RS06230	COG1404	Belongs to the peptidase S8 family
ADJ76_RS06235	COG2226	methyltransferase
ADJ76_RS06240	COG1169	isochorismate synthase
ADJ76_RS06250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADJ76_RS06255	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ADJ76_RS06260	COG4948	Mandelate Racemase Muconate Lactonizing
ADJ76_RS06265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADJ76_RS06270	COG0366	Alpha amylase catalytic
ADJ76_RS06305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADJ76_RS06315	COG0406	alpha-ribazole phosphatase activity
ADJ76_RS06325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADJ76_RS06330	COG0569	domain protein
ADJ76_RS06355	COG1404	Belongs to the peptidase S8 family
ADJ76_RS06375	COG4842	Belongs to the WXG100 family
ADJ76_RS06390	COG1674	ftsk spoiiie
ADJ76_RS06410	COG1404	Belongs to the peptidase S8 family
ADJ76_RS06415	COG1404	Belongs to the peptidase S8 family
ADJ76_RS06420	COG0515	serine threonine protein kinase
ADJ76_RS06445	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ADJ76_RS06460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADJ76_RS06470	COG0302	gtp cyclohydrolase
ADJ76_RS06475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADJ76_RS06490	COG0037	tRNA processing
ADJ76_RS06505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ADJ76_RS06510	COG0791	NLP P60 protein
ADJ76_RS06540	COG1136	(ABC) transporter
ADJ76_RS06550	COG1136	(ABC) transporter
ADJ76_RS06550	COG0577	efflux transmembrane transporter activity
ADJ76_RS06560	COG3470	protein probably involved in high-affinity Fe2 transport
ADJ76_RS06565	COG0672	)-iron permease
ADJ76_RS06575	COG0574	Belongs to the PEP-utilizing enzyme family
ADJ76_RS06575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADJ76_RS06590	COG2815	serine threonine protein kinase
ADJ76_RS06590	COG0515	serine threonine protein kinase
ADJ76_RS06605	COG0714	Associated with various cellular activities
ADJ76_RS06620	COG1490	D-aminoacyl-tRNA deacylase activity
ADJ76_RS06625	COG0354	folic acid binding
ADJ76_RS06630	COG3485	protocatechuate 3,4-dioxygenase
ADJ76_RS06640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADJ76_RS06670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADJ76_RS06680	COG1215	transferase activity, transferring glycosyl groups
ADJ76_RS06685	COG0215	cysteine-tRNA ligase activity
ADJ76_RS06690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADJ76_RS06700	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ADJ76_RS06740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADJ76_RS06745	COG1329	Transcriptional regulator
ADJ76_RS06750	COG0588	phosphoglycerate mutase activity
ADJ76_RS06755	COG2885	chlorophyll binding
ADJ76_RS06765	COG2885	chlorophyll binding
ADJ76_RS06780	COG0038	chloride channel
ADJ76_RS06785	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADJ76_RS06790	COG0783	Belongs to the Dps family
ADJ76_RS06810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADJ76_RS06815	COG1754	DNA topoisomerase type I activity
ADJ76_RS06815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADJ76_RS06855	COG2890	protein-(glutamine-N5) methyltransferase activity
ADJ76_RS06860	COG2354	Protein conserved in bacteria
ADJ76_RS06875	COG1297	OPT oligopeptide transporter protein
ADJ76_RS06880	COG3250	beta-galactosidase activity
ADJ76_RS06905	COG1404	Belongs to the peptidase S8 family
ADJ76_RS06935	COG0590	tRNA wobble adenosine to inosine editing
ADJ76_RS06940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADJ76_RS06950	COG2011	ABC-type metal ion transport system permease component
ADJ76_RS06955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADJ76_RS06960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADJ76_RS06965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADJ76_RS06970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADJ76_RS06995	COG2233	PERMEase
ADJ76_RS07025	COG4166	transmembrane transport
ADJ76_RS07030	COG0601	transmembrane transport
ADJ76_RS07035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADJ76_RS07045	COG1131	(ABC) transporter
ADJ76_RS07055	COG4585	Histidine kinase
ADJ76_RS07060	COG2197	response regulator
ADJ76_RS07075	COG1113	amino acid transport
ADJ76_RS07080	COG2860	membrane
ADJ76_RS07110	COG1643	Atp-dependent helicase
ADJ76_RS07120	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ADJ76_RS07125	COG0572	uridine kinase
ADJ76_RS07135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADJ76_RS07140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADJ76_RS07145	COG1760	l-serine dehydratase
ADJ76_RS07150	COG0577	efflux transmembrane transporter activity
ADJ76_RS07155	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADJ76_RS07155	COG1136	(ABC) transporter
ADJ76_RS07180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADJ76_RS07185	COG1780	Probably involved in ribonucleotide reductase function
ADJ76_RS07215	COG0745	RESPONSE REGULATOR receiver
ADJ76_RS07220	COG5002	protein histidine kinase activity
ADJ76_RS07250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADJ76_RS07270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADJ76_RS07275	COG1716	ATPase activity
ADJ76_RS07280	COG1716	ATPase activity
ADJ76_RS07295	COG0768	penicillin binding
ADJ76_RS07300	COG0515	serine threonine protein kinase
ADJ76_RS07305	COG0515	serine threonine protein kinase
ADJ76_RS07310	COG3764	Sortase (surface protein transpeptidase)
ADJ76_RS07330	COG0457	Tetratricopeptide repeat
ADJ76_RS07330	COG0705	Rhomboid family
ADJ76_RS07355	COG1404	Belongs to the peptidase S8 family
ADJ76_RS07385	COG1136	(ABC) transporter
ADJ76_RS07410	COG0596	Alpha beta hydrolase
ADJ76_RS07415	COG0778	Nitroreductase
ADJ76_RS07425	COG2204	response regulator
ADJ76_RS07430	COG4191	Histidine kinase
ADJ76_RS07435	COG0471	metal ion transport
ADJ76_RS07475	COG4585	Histidine kinase
ADJ76_RS07485	COG1136	(ABC) transporter
ADJ76_RS07490	COG2814	Major facilitator Superfamily
ADJ76_RS07500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ76_RS07505	COG1120	ATPase activity
ADJ76_RS07540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADJ76_RS07545	COG0113	porphobilinogen synthase activity
ADJ76_RS07555	COG0181	hydroxymethylbilane synthase activity
ADJ76_RS07560	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ADJ76_RS07565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADJ76_RS07570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADJ76_RS07580	COG0305	Participates in initiation and elongation during chromosome replication
ADJ76_RS07585	COG0534	Mate efflux family protein
ADJ76_RS07590	COG0360	Binds together with S18 to 16S ribosomal RNA
ADJ76_RS07600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADJ76_RS07605	COG0359	binds to the 23S rRNA
ADJ76_RS07610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADJ76_RS07615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ADJ76_RS07620	COG0617	tRNA 3'-terminal CCA addition
ADJ76_RS07640	COG0492	ferredoxin-NADP+ reductase activity
ADJ76_RS07645	COG3012	SEC-C Motif Domain Protein
ADJ76_RS07650	COG0671	phosphoesterase, PA-phosphatase related
ADJ76_RS07675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADJ76_RS07680	COG0187	DNA topoisomerase II activity
ADJ76_RS07695	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ADJ76_RS07700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADJ76_RS07705	COG0592	DNA-directed DNA polymerase activity
ADJ76_RS07710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADJ76_RS07715	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADJ76_RS07720	COG0594	ribonuclease P activity
ADJ76_RS07735	COG0357	Ribosomal RNA small subunit methyltransferase G
ADJ76_RS07740	COG1192	Involved in chromosome partitioning
ADJ76_RS07755	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADJ76_RS07760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADJ76_RS07785	COG1121	(ABC) transporter
ADJ76_RS07790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADJ76_RS07820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADJ76_RS07845	COG1129	ABC transporter
ADJ76_RS07855	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ76_RS07860	COG2376	Dihydroxyacetone kinase
ADJ76_RS07865	COG1461	Dihydroxyacetone kinase
ADJ76_RS07875	COG1129	ABC transporter
ADJ76_RS07880	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ76_RS07885	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ76_RS07890	COG0698	ribose 5-phosphate isomerase
ADJ76_RS07895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADJ76_RS07900	COG0800	Aldolase
ADJ76_RS07910	COG0246	Mannitol dehydrogenase
ADJ76_RS07915	COG1312	Catalyzes the dehydration of D-mannonate
ADJ76_RS07920	COG0477	Major facilitator Superfamily
ADJ76_RS07925	COG1063	alcohol dehydrogenase
ADJ76_RS07930	COG1757	Na H antiporter
ADJ76_RS07935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ADJ76_RS07940	COG2964	Protein conserved in bacteria
ADJ76_RS07955	COG1129	ABC transporter
ADJ76_RS07960	COG4214	carbohydrate transport
ADJ76_RS07965	COG1070	Carbohydrate kinase
ADJ76_RS07970	COG2115	Belongs to the xylose isomerase family
ADJ76_RS07980	COG0702	epimerase
ADJ76_RS08010	COG2814	Major facilitator Superfamily
ADJ76_RS08045	COG1113	amino acid transport
ADJ76_RS08055	COG4172	Belongs to the ABC transporter superfamily
ADJ76_RS08075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADJ76_RS08130	COG0077	Prephenate dehydratase
ADJ76_RS08135	COG1597	lipid kinase activity
ADJ76_RS08140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADJ76_RS08160	COG1069	ribulokinase activity
ADJ76_RS08170	COG1215	transferase activity, transferring glycosyl groups
ADJ76_RS08185	COG2217	Heavy metal translocating P-type atpase
ADJ76_RS08190	COG1937	Protein conserved in bacteria
ADJ76_RS08225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADJ76_RS08240	COG1950	PFAM Membrane protein of
ADJ76_RS08260	COG1408	metallophosphoesterase
ADJ76_RS08280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADJ76_RS08340	COG1111	helicase
ADJ76_RS08340	COG1205	dead DEAH box helicase
ADJ76_RS08450	COG1136	(ABC) transporter
ADJ76_RS08460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADJ76_RS08465	COG0745	RESPONSE REGULATOR receiver
ADJ76_RS08470	COG2205	protein histidine kinase activity
ADJ76_RS08500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ76_RS08515	COG0577	efflux transmembrane transporter activity
ADJ76_RS08515	COG1136	(ABC) transporter
ADJ76_RS08520	COG0577	efflux transmembrane transporter activity
ADJ76_RS08540	COG0717	Belongs to the dCTP deaminase family
ADJ76_RS08550	COG2181	nitrate reductase activity
ADJ76_RS08550	COG0247	lactate metabolic process
ADJ76_RS08615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADJ76_RS08625	COG1397	ADP-ribosylglycohydrolase
ADJ76_RS08640	COG0406	alpha-ribazole phosphatase activity
ADJ76_RS08640	COG0494	nUDIX hydrolase
ADJ76_RS08655	COG0306	phosphate transporter
ADJ76_RS08665	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ADJ76_RS08675	COG0714	Associated with various cellular activities
ADJ76_RS08760	COG1136	(ABC) transporter
ADJ76_RS08805	COG2985	domain, Protein
ADJ76_RS08805	COG0569	domain protein
ADJ76_RS08815	COG1362	aminopeptidase activity
ADJ76_RS08830	COG0346	lactoylglutathione lyase activity
ADJ76_RS08840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADJ76_RS08850	COG0443	Heat shock 70 kDa protein
ADJ76_RS08860	COG0484	heat shock protein binding
ADJ76_RS08865	COG0789	Transcriptional regulator
ADJ76_RS08870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)