locus-tag	class	description
AN27039_RS00020	COG2966	Psort location CytoplasmicMembrane, score
AN27039_RS00055	COG0154	amidase activity
AN27039_RS00060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN27039_RS00135	COG1174	glycine betaine transport
AN27039_RS00145	COG0346	lactoylglutathione lyase activity
AN27039_RS00210	COG0513	Belongs to the DEAD box helicase family
AN27039_RS00215	COG2095	MarC family integral membrane protein
AN27039_RS00245	COG1082	Xylose isomerase domain protein TIM barrel
AN27039_RS00285	COG1611	Belongs to the LOG family
AN27039_RS00305	COG1321	iron dependent repressor
AN27039_RS00305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN27039_RS00310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN27039_RS00315	COG1121	(ABC) transporter
AN27039_RS00365	COG1744	ABC transporter substrate-binding protein PnrA-like
AN27039_RS00415	COG1136	(ABC) transporter
AN27039_RS00415	COG0577	efflux transmembrane transporter activity
AN27039_RS00425	COG1254	Belongs to the acylphosphatase family
AN27039_RS00445	COG1621	beta-fructofuranosidase activity
AN27039_RS00450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AN27039_RS00470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AN27039_RS00480	COG0254	rRNA binding
AN27039_RS00485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN27039_RS00535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AN27039_RS00540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AN27039_RS00545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AN27039_RS00550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AN27039_RS00555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AN27039_RS00585	COG2197	response regulator
AN27039_RS00590	COG2205	protein histidine kinase activity
AN27039_RS00610	COG0693	protein deglycase activity
AN27039_RS00650	COG0596	Alpha beta hydrolase
AN27039_RS00655	COG3321	synthase
AN27039_RS00655	COG1028	Short-chain dehydrogenase reductase Sdr
AN27039_RS00655	COG0604	alcohol dehydrogenase
AN27039_RS00660	COG1733	regulation of RNA biosynthetic process
AN27039_RS00710	COG4585	Histidine kinase
AN27039_RS00715	COG1131	(ABC) transporter
AN27039_RS00765	COG3962	Belongs to the TPP enzyme family
AN27039_RS00785	COG2188	Transcriptional regulator
AN27039_RS00805	COG2017	converts alpha-aldose to the beta-anomer
AN27039_RS00815	COG0673	inositol 2-dehydrogenase activity
AN27039_RS00820	COG2814	Major facilitator Superfamily
AN27039_RS00860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN27039_RS00880	COG4585	Histidine kinase
AN27039_RS00885	COG2197	response regulator
AN27039_RS00895	COG0328	RNA-DNA hybrid ribonuclease activity
AN27039_RS00915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN27039_RS00920	COG0516	GMP reductase activity
AN27039_RS00940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AN27039_RS00945	COG2949	membrane
AN27039_RS00980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN27039_RS01025	COG0736	holo-[acyl-carrier-protein] synthase activity
AN27039_RS01035	COG1072	(Pantothenic acid kinase))
AN27039_RS01095	COG1285	pathogenesis
AN27039_RS01115	COG0202	RNA polymerase activity
AN27039_RS01125	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AN27039_RS01130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN27039_RS01145	COG0563	adenylate kinase activity
AN27039_RS01160	COG1841	ribosomal large subunit assembly
AN27039_RS01165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AN27039_RS01170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AN27039_RS01175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AN27039_RS01180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AN27039_RS01185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AN27039_RS01190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AN27039_RS01195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AN27039_RS01200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AN27039_RS01210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AN27039_RS01220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AN27039_RS01235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AN27039_RS01240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AN27039_RS01245	COG0089	rRNA binding
AN27039_RS01260	COG0051	transcription antitermination factor activity, RNA binding
AN27039_RS01290	COG0049	tRNA binding
AN27039_RS01295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AN27039_RS01315	COG2894	cell division
AN27039_RS01385	COG2885	chlorophyll binding
AN27039_RS01415	COG0081	regulation of translation
AN27039_RS01430	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN27039_RS01455	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AN27039_RS01495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN27039_RS01495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN27039_RS01495	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AN27039_RS01500	COG1461	Dihydroxyacetone kinase
AN27039_RS01505	COG2376	Dihydroxyacetone kinase
AN27039_RS01545	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AN27039_RS01575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AN27039_RS01585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AN27039_RS01595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN27039_RS01615	COG0247	lactate metabolic process
AN27039_RS01620	COG1139	Iron-sulfur cluster binding protein
AN27039_RS01640	COG3104	oligopeptide transport
AN27039_RS01645	COG3104	oligopeptide transport
AN27039_RS01660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN27039_RS01690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN27039_RS01725	COG1136	(ABC) transporter
AN27039_RS01740	COG3599	regulation of cell shape
AN27039_RS01760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AN27039_RS01810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AN27039_RS01820	COG1136	(ABC) transporter
AN27039_RS01830	COG2197	response regulator
AN27039_RS01840	COG2076	Multidrug Resistance protein
AN27039_RS01865	COG0302	gtp cyclohydrolase
AN27039_RS01870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN27039_RS01885	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AN27039_RS01900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AN27039_RS01910	COG2873	o-acetylhomoserine
AN27039_RS01955	COG0012	GTP binding
AN27039_RS01970	COG2261	transglycosylase associated protein
AN27039_RS01995	COG1595	DNA-templated transcription, initiation
AN27039_RS02015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AN27039_RS02025	COG1722	exodeoxyribonuclease VII activity
AN27039_RS02105	COG1136	(ABC) transporter
AN27039_RS02110	COG0577	efflux transmembrane transporter activity
AN27039_RS02120	COG1132	(ABC) transporter
AN27039_RS02150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AN27039_RS02165	COG0557	exoribonuclease II activity
AN27039_RS02185	COG1349	DNA-binding transcription factor activity
AN27039_RS02195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN27039_RS02325	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AN27039_RS02365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AN27039_RS02395	COG0191	fructose-bisphosphate aldolase activity
AN27039_RS02400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN27039_RS02405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AN27039_RS02410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AN27039_RS02415	COG1028	Short-chain dehydrogenase reductase Sdr
AN27039_RS02440	COG0717	Belongs to the dCTP deaminase family
AN27039_RS02505	COG0714	Associated with various cellular activities
AN27039_RS02540	COG1051	belongs to the nudix hydrolase family
AN27039_RS02585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN27039_RS02690	COG0745	RESPONSE REGULATOR receiver
AN27039_RS02695	COG5002	protein histidine kinase activity
AN27039_RS02705	COG0588	phosphoglycerate mutase activity
AN27039_RS02720	COG1113	amino acid transport
AN27039_RS02780	COG2188	Transcriptional regulator
AN27039_RS02795	COG0642	Histidine kinase
AN27039_RS02800	COG0745	RESPONSE REGULATOR receiver
AN27039_RS02810	COG1754	DNA topoisomerase type I activity
AN27039_RS02810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN27039_RS02825	COG0745	RESPONSE REGULATOR receiver
AN27039_RS02855	COG2890	protein-(glutamine-N5) methyltransferase activity
AN27039_RS02865	COG0450	alkyl hydroperoxide reductase
AN27039_RS02935	COG3548	integral membrane protein
AN27039_RS02950	COG1136	(ABC) transporter
AN27039_RS02950	COG0577	efflux transmembrane transporter activity
AN27039_RS02980	COG1408	metallophosphoesterase
AN27039_RS03025	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AN27039_RS03025	COG1918	ferrous iron import across plasma membrane
AN27039_RS03040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AN27039_RS03040	COG1918	ferrous iron import across plasma membrane
AN27039_RS03135	COG0113	porphobilinogen synthase activity
AN27039_RS03140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN27039_RS03150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN27039_RS03180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN27039_RS03200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN27039_RS03255	COG2233	PERMEase
AN27039_RS03280	COG0702	epimerase
AN27039_RS03330	COG0590	tRNA wobble adenosine to inosine editing
AN27039_RS03330	COG0037	tRNA processing
AN27039_RS03340	COG0656	L-ascorbic acid biosynthetic process
AN27039_RS03345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AN27039_RS03375	COG0577	efflux transmembrane transporter activity
AN27039_RS03375	COG1136	(ABC) transporter
AN27039_RS03380	COG1464	Belongs to the NlpA lipoprotein family
AN27039_RS03400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN27039_RS03450	COG0463	Glycosyl transferase, family 2
AN27039_RS03460	COG1309	transcriptional regulator
AN27039_RS03545	COG1950	PFAM Membrane protein of
AN27039_RS03590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN27039_RS03640	COG2197	response regulator
AN27039_RS03650	COG1937	Protein conserved in bacteria
AN27039_RS03810	COG1653	transport
AN27039_RS03815	COG0561	phosphatase activity
AN27039_RS03840	COG1309	transcriptional regulator
AN27039_RS03860	COG0672	)-iron permease
AN27039_RS03925	COG1072	(Pantothenic acid kinase))
AN27039_RS03940	COG1780	Probably involved in ribonucleotide reductase function
AN27039_RS03985	COG1733	regulation of RNA biosynthetic process
AN27039_RS03995	COG0351	phosphomethylpyrimidine kinase
AN27039_RS04005	COG1121	(ABC) transporter
AN27039_RS04030	COG0359	binds to the 23S rRNA
AN27039_RS04035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AN27039_RS04045	COG0360	Binds together with S18 to 16S ribosomal RNA
AN27039_RS04120	COG1476	TRANSCRIPTIONal
AN27039_RS04150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN27039_RS04165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AN27039_RS04170	COG0592	DNA-directed DNA polymerase activity
AN27039_RS04180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AN27039_RS04185	COG0594	ribonuclease P activity
AN27039_RS04190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AN27039_RS04235	COG3118	belongs to the thioredoxin family
AN27039_RS04240	COG0492	ferredoxin-NADP+ reductase activity
AN27039_RS04270	COG0673	inositol 2-dehydrogenase activity
AN27039_RS04275	COG3345	alpha-galactosidase
AN27039_RS04330	COG2815	serine threonine protein kinase
AN27039_RS04330	COG0515	serine threonine protein kinase
AN27039_RS04360	COG1716	ATPase activity
AN27039_RS04385	COG0569	domain protein
AN27039_RS04385	COG2985	domain, Protein
AN27039_RS04395	COG0789	Transcriptional regulator
AN27039_RS04415	COG2409	Drug exporters of the RND superfamily
AN27039_RS04440	COG1940	carbohydrate kinase activity
AN27039_RS04445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AN27039_RS04445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN27039_RS04450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN27039_RS04455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN27039_RS04495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN27039_RS04535	COG1131	(ABC) transporter
AN27039_RS04590	COG4585	Histidine kinase
AN27039_RS04595	COG2197	response regulator
AN27039_RS04600	COG2197	response regulator
AN27039_RS04620	COG1121	(ABC) transporter
AN27039_RS04690	COG3842	ATPase activity
AN27039_RS04700	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AN27039_RS04700	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AN27039_RS04845	COG0778	Nitroreductase
AN27039_RS04890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN27039_RS04920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN27039_RS04925	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AN27039_RS04935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN27039_RS04950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AN27039_RS04955	COG0484	heat shock protein binding
AN27039_RS04985	COG2205	protein histidine kinase activity
AN27039_RS05010	COG1136	(ABC) transporter
AN27039_RS05010	COG0577	efflux transmembrane transporter activity
AN27039_RS05025	COG3655	Transcriptional regulator
AN27039_RS05075	COG1609	Transcriptional regulator
AN27039_RS05080	COG1621	beta-fructofuranosidase activity
AN27039_RS05105	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN27039_RS05115	COG3715	PTS system
AN27039_RS05140	COG0561	phosphatase activity
AN27039_RS05160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN27039_RS05240	COG3842	ATPase activity
AN27039_RS05260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN27039_RS05265	COG0215	cysteine-tRNA ligase activity
AN27039_RS05280	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AN27039_RS05295	COG0459	protein refolding
AN27039_RS05315	COG0745	RESPONSE REGULATOR receiver
AN27039_RS05325	COG1842	Phage shock protein A
AN27039_RS05335	COG0519	Catalyzes the synthesis of GMP from XMP
AN27039_RS05370	COG0789	Transcriptional regulator
AN27039_RS05455	COG1970	mechanosensitive ion channel activity
AN27039_RS05465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN27039_RS05495	COG1215	transferase activity, transferring glycosyl groups
AN27039_RS05500	COG1297	OPT oligopeptide transporter protein
AN27039_RS05550	COG1335	isochorismatase
AN27039_RS05580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AN27039_RS05585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AN27039_RS05650	COG0714	Associated with various cellular activities
AN27039_RS05665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AN27039_RS05750	COG1309	transcriptional regulator
AN27039_RS05765	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AN27039_RS05795	COG1136	(ABC) transporter
AN27039_RS05865	COG2197	response regulator
AN27039_RS05915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN27039_RS05960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN27039_RS05975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AN27039_RS05980	COG0513	Belongs to the DEAD box helicase family
AN27039_RS06030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN27039_RS06035	COG0745	RESPONSE REGULATOR receiver
AN27039_RS06045	COG3485	protocatechuate 3,4-dioxygenase
AN27039_RS06060	COG1490	D-aminoacyl-tRNA deacylase activity
AN27039_RS06135	COG0745	RESPONSE REGULATOR receiver
AN27039_RS06140	COG2205	protein histidine kinase activity
AN27039_RS06225	COG2211	Major facilitator Superfamily
AN27039_RS06235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN27039_RS06235	COG0574	Belongs to the PEP-utilizing enzyme family
AN27039_RS06270	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN27039_RS06270	COG0596	Alpha beta hydrolase
AN27039_RS06285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN27039_RS06290	COG0698	ribose 5-phosphate isomerase
AN27039_RS06300	COG0698	ribose 5-phosphate isomerase
AN27039_RS06395	COG0546	phosphoglycolate phosphatase activity
AN27039_RS06410	COG0604	alcohol dehydrogenase
AN27039_RS06415	COG1733	regulation of RNA biosynthetic process
AN27039_RS06455	COG0601	transmembrane transport
AN27039_RS06460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN27039_RS06570	COG1053	succinate dehydrogenase
AN27039_RS06605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN27039_RS06610	COG1397	ADP-ribosylglycohydrolase
AN27039_RS06655	COG2197	response regulator
AN27039_RS06675	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AN27039_RS06690	COG0395	ABC-type sugar transport system, permease component
AN27039_RS06695	COG1175	transmembrane transport
AN27039_RS06720	COG4176	ABC-type proline glycine betaine transport system permease component
AN27039_RS06760	COG2226	methyltransferase
AN27039_RS06765	COG0644	oxidoreductase
AN27039_RS06775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN27039_RS06820	COG0713	ATP synthesis coupled electron transport
AN27039_RS06840	COG0142	geranyltranstransferase activity
AN27039_RS06865	COG0501	Belongs to the peptidase M48B family
AN27039_RS06885	COG2197	response regulator
AN27039_RS06890	COG1666	GTP binding
AN27039_RS06910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AN27039_RS06940	COG0745	RESPONSE REGULATOR receiver
AN27039_RS06945	COG5002	protein histidine kinase activity
AN27039_RS06950	COG0586	Pfam SNARE associated Golgi protein
AN27039_RS06980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN27039_RS07020	COG0673	inositol 2-dehydrogenase activity
AN27039_RS07070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AN27039_RS07155	COG1216	Glycosyl transferase, family 2
AN27039_RS07155	COG0463	Glycosyl transferase, family 2
AN27039_RS07165	COG0438	transferase activity, transferring glycosyl groups
AN27039_RS07195	COG1482	cell wall glycoprotein biosynthetic process
AN27039_RS07230	COG2835	tetraacyldisaccharide 4'-kinase activity
AN27039_RS07270	COG0745	RESPONSE REGULATOR receiver
AN27039_RS07280	COG5401	PFAM Sporulation and spore germination
AN27039_RS07285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AN27039_RS07335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AN27039_RS07340	COG0222	ribosome binding
AN27039_RS07350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AN27039_RS07490	COG1968	undecaprenyl-diphosphatase activity
AN27039_RS07500	COG0483	inositol monophosphate 1-phosphatase activity
AN27039_RS07505	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN27039_RS07510	COG0456	acetyltransferase
AN27039_RS07515	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN27039_RS07525	COG1120	ATPase activity
AN27039_RS07630	COG0315	cyclic pyranopterin monophosphate synthase activity
AN27039_RS07640	COG0314	molybdopterin synthase activity
AN27039_RS07650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AN27039_RS07680	COG1162	GTPase activity
AN27039_RS07685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AN27039_RS07700	COG1595	DNA-templated transcription, initiation
AN27039_RS07720	COG0567	Dehydrogenase, E1 component
AN27039_RS07720	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN27039_RS07735	COG0731	radical SAM domain protein
AN27039_RS07740	COG1253	flavin adenine dinucleotide binding
AN27039_RS07750	COG0739	heme binding
AN27039_RS07770	COG0019	diaminopimelate decarboxylase activity
AN27039_RS07780	COG0460	homoserine dehydrogenase
AN27039_RS07790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN27039_RS07810	COG0254	rRNA binding
AN27039_RS07825	COG1846	Transcriptional regulator
AN27039_RS07830	COG0604	alcohol dehydrogenase
AN27039_RS07840	COG0693	protein deglycase activity
AN27039_RS07860	COG0110	maltose O-acetyltransferase activity
AN27039_RS07895	COG0205	6-phosphofructokinase activity
AN27039_RS07905	COG0045	succinate-CoA ligase (ADP-forming) activity
AN27039_RS07950	COG0039	L-malate dehydrogenase activity
AN27039_RS07965	COG0395	ABC-type sugar transport system, permease component
AN27039_RS08000	COG0058	SHG alpha-glucan phosphorylase activity
AN27039_RS08040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AN27039_RS08065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN27039_RS08085	COG3480	Lon protease (S16) C-terminal proteolytic domain
AN27039_RS08125	COG2326	polyphosphate kinase activity
AN27039_RS08230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN27039_RS08235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN27039_RS08250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN27039_RS08255	COG2188	Transcriptional regulator
AN27039_RS08305	COG1045	serine acetyltransferase
AN27039_RS08340	COG0544	peptidyl-prolyl cis-trans isomerase activity
AN27039_RS08360	COG0740	serine-type endopeptidase activity
AN27039_RS08365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AN27039_RS08370	COG0287	Prephenate dehydrogenase
AN27039_RS08370	COG1605	Chorismate mutase
AN27039_RS08405	COG1609	Transcriptional regulator
AN27039_RS08425	COG4122	O-methyltransferase activity
AN27039_RS08445	COG1122	ATPase activity
AN27039_RS08450	COG2375	cellular response to nickel ion
AN27039_RS08450	COG1132	(ABC) transporter
AN27039_RS08480	COG0730	response to heat
AN27039_RS08485	COG1648	precorrin-2 dehydrogenase activity
AN27039_RS08485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN27039_RS08510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN27039_RS08520	COG4221	oxidoreductase activity
AN27039_RS08595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AN27039_RS08600	COG0285	dihydrofolate synthase activity
AN27039_RS08605	COG1461	Dihydroxyacetone kinase
AN27039_RS08610	COG0105	UTP biosynthetic process
AN27039_RS08620	COG4152	abc transporter atp-binding protein
AN27039_RS08625	COG1196	nuclear chromosome segregation
AN27039_RS08645	COG4585	Histidine kinase
AN27039_RS08650	COG0842	Transport permease protein
AN27039_RS08655	COG1131	(ABC) transporter
AN27039_RS08665	COG2197	response regulator
AN27039_RS08670	COG4585	Histidine kinase
AN27039_RS08695	COG1837	Belongs to the UPF0109 family
AN27039_RS08710	COG0681	Belongs to the peptidase S26 family
AN27039_RS08735	COG0792	nuclease activity
AN27039_RS08775	COG0052	Belongs to the universal ribosomal protein uS2 family
AN27039_RS08780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AN27039_RS08790	COG0233	cytoplasmic translational termination
AN27039_RS08810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AN27039_RS08820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AN27039_RS08900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN27039_RS08915	COG0330	HflC and HflK could
AN27039_RS08925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AN27039_RS08930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AN27039_RS08940	COG0577	efflux transmembrane transporter activity
AN27039_RS08940	COG1136	(ABC) transporter
AN27039_RS08960	COG1454	alcohol dehydrogenase
AN27039_RS08970	COG0612	Peptidase, M16
AN27039_RS08975	COG0300	oxidoreductase activity
AN27039_RS09000	COG0318	PFAM AMP-dependent synthetase and ligase
AN27039_RS09035	COG2001	Belongs to the MraZ family
AN27039_RS09100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN27039_RS09105	COG1496	oxidoreductase activity
AN27039_RS09110	COG1799	cell septum assembly
AN27039_RS09125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AN27039_RS09155	COG2501	S4 domain
AN27039_RS09180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AN27039_RS09230	COG0131	Imidazoleglycerol-phosphate dehydratase
AN27039_RS09245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AN27039_RS09250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AN27039_RS09295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AN27039_RS09300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AN27039_RS09305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN27039_RS09330	COG0765	amino acid transport
AN27039_RS09335	COG0765	amino acid transport
AN27039_RS09345	COG1131	(ABC) transporter
AN27039_RS09355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AN27039_RS09375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AN27039_RS09385	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AN27039_RS09390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN27039_RS09400	COG0137	argininosuccinate synthase activity
AN27039_RS09405	COG2116	formate transmembrane transporter activity
AN27039_RS09465	COG0647	UMP catabolic process
AN27039_RS09480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN27039_RS09485	COG0497	DNA recombination
AN27039_RS09515	COG0494	nUDIX hydrolase
AN27039_RS09520	COG1609	Transcriptional regulator
AN27039_RS09530	COG1175	transmembrane transport
AN27039_RS09535	COG0395	ABC-type sugar transport system, permease component
AN27039_RS09540	COG1621	beta-fructofuranosidase activity
AN27039_RS09560	COG0719	Fe-S assembly protein
AN27039_RS09565	COG0396	ATPase activity
AN27039_RS09670	COG3833	ABC-type maltose transport systems, permease component
AN27039_RS09725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN27039_RS09735	COG1027	Aspartate ammonia-lyase
AN27039_RS09765	COG0436	Aminotransferase
AN27039_RS09905	COG3022	response to hydroperoxide
AN27039_RS09925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AN27039_RS09940	COG0406	alpha-ribazole phosphatase activity
AN27039_RS09975	COG0321	lipoyl(octanoyl) transferase activity
AN27039_RS10110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN27039_RS10130	COG0438	transferase activity, transferring glycosyl groups
AN27039_RS10145	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AN27039_RS10150	COG1051	belongs to the nudix hydrolase family
AN27039_RS10155	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AN27039_RS10160	COG0217	transcriptional regulatory protein
AN27039_RS10165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AN27039_RS10195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN27039_RS10200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN27039_RS10210	COG0789	Transcriptional regulator
AN27039_RS10220	COG1196	nuclear chromosome segregation
AN27039_RS10235	COG0124	histidyl-tRNA synthetase
AN27039_RS10265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN27039_RS10265	COG1116	anion transmembrane transporter activity
AN27039_RS10295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AN27039_RS10345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN27039_RS10360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AN27039_RS10370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN27039_RS10375	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AN27039_RS10380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN27039_RS10405	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AN27039_RS10430	COG0284	orotidine-5'-phosphate decarboxylase activity
AN27039_RS10455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AN27039_RS10480	COG1834	amidinotransferase
AN27039_RS10490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AN27039_RS10505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN27039_RS10535	COG0736	holo-[acyl-carrier-protein] synthase activity
AN27039_RS10540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN27039_RS10545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN27039_RS10550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN27039_RS10555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AN27039_RS10560	COG0140	phosphoribosyl-ATP diphosphatase activity
AN27039_RS10585	COG2197	response regulator
AN27039_RS10590	COG4585	Histidine kinase
AN27039_RS10615	COG0805	protein transport
AN27039_RS10640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AN27039_RS10665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN27039_RS10675	COG1136	(ABC) transporter
AN27039_RS10715	COG0667	Aldo Keto reductase
AN27039_RS10735	COG1716	ATPase activity
AN27039_RS10810	COG1160	GTP binding
AN27039_RS10825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AN27039_RS10845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN27039_RS10850	COG0149	triose-phosphate isomerase activity
AN27039_RS10875	COG1660	Displays ATPase and GTPase activities
AN27039_RS10890	COG3585	molybdate ion transport
AN27039_RS10955	COG0237	dephospho-CoA kinase activity
AN27039_RS10975	COG2050	protein possibly involved in aromatic compounds catabolism
AN27039_RS11005	COG0134	indole-3-glycerol-phosphate synthase activity
AN27039_RS11030	COG0107	imidazoleglycerol-phosphate synthase activity
AN27039_RS11040	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AN27039_RS11070	COG2837	iron assimilation
AN27039_RS11075	COG0517	IMP dehydrogenase activity
AN27039_RS11075	COG1994	Peptidase M50
AN27039_RS11085	COG2391	methyltransferase activity
AN27039_RS11090	COG0425	Belongs to the sulfur carrier protein TusA family
AN27039_RS11095	COG0667	Aldo Keto reductase
AN27039_RS11110	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN27039_RS11115	COG4607	ABC-type enterochelin transport system periplasmic component
AN27039_RS11125	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN27039_RS11205	COG1435	thymidine kinase activity
AN27039_RS11210	COG0671	phosphoesterase, PA-phosphatase related
AN27039_RS11225	COG1881	PFAM PEBP family protein
AN27039_RS11230	COG4221	oxidoreductase activity
AN27039_RS11250	COG4555	ABC transporter
AN27039_RS11295	COG0569	domain protein
AN27039_RS11355	COG0187	DNA topoisomerase II activity
AN27039_RS11505	COG0423	glycine-tRNA ligase activity
AN27039_RS11535	COG1381	Involved in DNA repair and RecF pathway recombination
AN27039_RS11555	COG1476	TRANSCRIPTIONal
AN27039_RS11565	COG3609	addiction module antidote protein, CC2985 family
AN27039_RS11575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN27039_RS11640	COG0484	heat shock protein binding
AN27039_RS11645	COG1420	regulation of RNA biosynthetic process
AN27039_RS11660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AN27039_RS11680	COG2807	transmembrane transport
AN27039_RS11685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AN27039_RS11705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN27039_RS11710	COG0512	Glutamine amidotransferase of anthranilate synthase
AN27039_RS11725	COG0159	tryptophan synthase activity
AN27039_RS11745	COG0268	Binds directly to 16S ribosomal RNA
AN27039_RS11770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AN27039_RS11805	COG0495	leucyl-tRNA aminoacylation
AN27039_RS11820	COG0537	adenosine 5'-monophosphoramidase activity
AN27039_RS11870	COG2095	MarC family integral membrane protein
AN27039_RS11885	COG0406	alpha-ribazole phosphatase activity
AN27039_RS11890	COG0799	negative regulation of ribosome biogenesis
AN27039_RS11930	COG1132	(ABC) transporter
AN27039_RS11945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AN27039_RS11950	COG2205	protein histidine kinase activity
AN27039_RS11965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AN27039_RS11975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AN27039_RS11980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AN27039_RS11985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AN27039_RS12005	COG1294	oxidase, subunit
AN27039_RS12030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AN27039_RS12035	COG0571	ribonuclease III activity
AN27039_RS12050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AN27039_RS12055	COG1609	Transcriptional regulator
AN27039_RS12060	COG0738	Major facilitator superfamily
AN27039_RS12065	COG4154	Belongs to the RbsD FucU family
AN27039_RS12070	COG4806	L-rhamnose isomerase
AN27039_RS12070	COG1070	Carbohydrate kinase
AN27039_RS12080	COG0235	Class ii aldolase
AN27039_RS12100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AN27039_RS12125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN27039_RS12130	COG0066	3-isopropylmalate dehydratase activity
AN27039_RS12150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AN27039_RS12175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN27039_RS12190	COG2813	Specifically methylates the guanine in position
AN27039_RS12250	COG0509	glycine decarboxylation via glycine cleavage system
AN27039_RS12270	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AN27039_RS12275	COG2137	regulation of response to DNA damage stimulus
AN27039_RS12280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AN27039_RS12290	COG1396	sequence-specific DNA binding
AN27039_RS12295	COG1058	Belongs to the CinA family
AN27039_RS12295	COG1546	Belongs to the CinA family
AN27039_RS12315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN27039_RS12375	COG1115	amino acid carrier protein
AN27039_RS12380	COG1115	amino acid carrier protein
AN27039_RS12385	COG1115	amino acid carrier protein
AN27039_RS12390	COG1115	amino acid carrier protein
AN27039_RS12415	COG2040	homocysteine
AN27039_RS12420	COG0833	amino acid
AN27039_RS12480	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AN27039_RS12485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AN27039_RS12515	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AN27039_RS12560	COG1940	carbohydrate kinase activity
AN27039_RS12625	COG2884	Cell division ATP-binding protein ftsE
AN27039_RS12675	COG1716	ATPase activity
AN27039_RS12675	COG1131	(ABC) transporter
AN27039_RS12675	COG0842	Transport permease protein
AN27039_RS12685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AN27039_RS12700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AN27039_RS12710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN27039_RS12730	COG1134	teichoic acid transport
AN27039_RS12740	COG0463	Glycosyl transferase, family 2
AN27039_RS12765	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AN27039_RS12775	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AN27039_RS12785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN27039_RS12800	COG0473	3-isopropylmalate dehydrogenase activity