locus-tag	class	description
CWT10_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CWT10_RS00010	COG0592	DNA-directed DNA polymerase activity
CWT10_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWT10_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CWT10_RS00025	COG1129	ABC transporter
CWT10_RS00040	COG0187	DNA topoisomerase II activity
CWT10_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CWT10_RS00080	COG0656	L-ascorbic acid biosynthetic process
CWT10_RS00090	COG3764	Sortase (surface protein transpeptidase)
CWT10_RS00095	COG0515	serine threonine protein kinase
CWT10_RS00100	COG0515	serine threonine protein kinase
CWT10_RS00105	COG0768	penicillin binding
CWT10_RS00120	COG1716	ATPase activity
CWT10_RS00125	COG1716	ATPase activity
CWT10_RS00140	COG0569	domain protein
CWT10_RS00140	COG2985	domain, Protein
CWT10_RS00145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWT10_RS00150	COG1854	S-ribosylhomocysteine lyase activity
CWT10_RS00160	COG0471	metal ion transport
CWT10_RS00165	COG3852	Histidine kinase
CWT10_RS00175	COG0628	permease
CWT10_RS00255	COG1120	ATPase activity
CWT10_RS00260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWT10_RS00265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWT10_RS00275	COG0110	maltose O-acetyltransferase activity
CWT10_RS00290	COG1940	carbohydrate kinase activity
CWT10_RS00295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CWT10_RS00295	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CWT10_RS00345	COG1609	Transcriptional regulator
CWT10_RS00355	COG1175	transmembrane transport
CWT10_RS00360	COG0395	ABC-type sugar transport system, permease component
CWT10_RS00385	COG1028	Short-chain dehydrogenase reductase Sdr
CWT10_RS00395	COG0673	inositol 2-dehydrogenase activity
CWT10_RS00485	COG1131	(ABC) transporter
CWT10_RS00520	COG1937	Protein conserved in bacteria
CWT10_RS00525	COG0395	ABC-type sugar transport system, permease component
CWT10_RS00530	COG1175	transmembrane transport
CWT10_RS00550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWT10_RS00575	COG1950	PFAM Membrane protein of
CWT10_RS00580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWT10_RS00610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CWT10_RS00620	COG0519	Catalyzes the synthesis of GMP from XMP
CWT10_RS00620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CWT10_RS00770	COG1674	ftsk spoiiie
CWT10_RS00795	COG1827	regulation of RNA biosynthetic process
CWT10_RS00805	COG1780	Probably involved in ribonucleotide reductase function
CWT10_RS00810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWT10_RS00815	COG3386	PFAM SMP-30 Gluconolaconase
CWT10_RS00825	COG1253	flavin adenine dinucleotide binding
CWT10_RS00835	COG0563	adenylate kinase activity
CWT10_RS00890	COG1378	Sugar-specific transcriptional regulator TrmB
CWT10_RS00900	COG1757	Na H antiporter
CWT10_RS00930	COG4245	von Willebrand factor, type A
CWT10_RS00970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWT10_RS00985	COG3842	ATPase activity
CWT10_RS00990	COG1178	ABC-type Fe3 transport system permease component
CWT10_RS01000	COG1840	ABC-type Fe3 transport system, periplasmic component
CWT10_RS01010	COG5002	protein histidine kinase activity
CWT10_RS01060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CWT10_RS01070	COG1653	transport
CWT10_RS01100	COG3833	ABC-type maltose transport systems, permease component
CWT10_RS01105	COG1175	transmembrane transport
CWT10_RS01135	COG2801	Transposase and inactivated derivatives
CWT10_RS01175	COG2801	Transposase and inactivated derivatives
CWT10_RS01180	COG2801	Transposase and inactivated derivatives
CWT10_RS01200	COG0778	Nitroreductase
CWT10_RS01210	COG2188	Transcriptional regulator
CWT10_RS01215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWT10_RS01220	COG1063	alcohol dehydrogenase
CWT10_RS01225	COG2814	Major facilitator Superfamily
CWT10_RS01230	COG0191	fructose-bisphosphate aldolase activity
CWT10_RS01235	COG1063	alcohol dehydrogenase
CWT10_RS01240	COG2271	Major facilitator Superfamily
CWT10_RS01255	COG1404	Belongs to the peptidase S8 family
CWT10_RS01305	COG0626	cystathionine gamma-synthase activity
CWT10_RS01310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CWT10_RS01315	COG1132	(ABC) transporter
CWT10_RS01320	COG1132	(ABC) transporter
CWT10_RS01340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWT10_RS01370	COG1201	RNA secondary structure unwinding
CWT10_RS01400	COG1131	(ABC) transporter
CWT10_RS01405	COG0247	lactate metabolic process
CWT10_RS01405	COG2181	nitrate reductase activity
CWT10_RS01530	COG1175	transmembrane transport
CWT10_RS01535	COG3842	ATPase activity
CWT10_RS01545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWT10_RS01615	COG4691	Plasmid stability protein
CWT10_RS01640	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWT10_RS01680	COG1569	PIN domain
CWT10_RS01685	COG3311	Transcriptional regulator
CWT10_RS01760	COG2337	Toxic component of a toxin-antitoxin (TA) module
CWT10_RS01820	COG2197	response regulator
CWT10_RS01830	COG0463	Glycosyl transferase, family 2
CWT10_RS01840	COG0745	RESPONSE REGULATOR receiver
CWT10_RS01850	COG3485	protocatechuate 3,4-dioxygenase
CWT10_RS01875	COG4555	ABC transporter
CWT10_RS01885	COG1490	D-aminoacyl-tRNA deacylase activity
CWT10_RS01935	COG0297	glycogen (starch) synthase activity
CWT10_RS01935	COG0438	transferase activity, transferring glycosyl groups
CWT10_RS01945	COG0574	Belongs to the PEP-utilizing enzyme family
CWT10_RS01945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWT10_RS01950	COG0714	Associated with various cellular activities
CWT10_RS01970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWT10_RS01975	COG2873	o-acetylhomoserine
CWT10_RS01980	COG0791	NLP P60 protein
CWT10_RS01985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CWT10_RS01990	COG2027	D-alanyl-D-alanine carboxypeptidase
CWT10_RS02015	COG2885	chlorophyll binding
CWT10_RS02045	COG1518	maintenance of DNA repeat elements
CWT10_RS02050	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CWT10_RS02140	COG0302	gtp cyclohydrolase
CWT10_RS02145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CWT10_RS02150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CWT10_RS02165	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CWT10_RS02180	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CWT10_RS02190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CWT10_RS02195	COG1737	Transcriptional regulator
CWT10_RS02200	COG2723	6-phospho-beta-galactosidase activity
CWT10_RS02205	COG1263	PTS System
CWT10_RS02205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWT10_RS02205	COG2190	(PTS) system
CWT10_RS02215	COG1136	(ABC) transporter
CWT10_RS02245	COG3414	Phosphotransferase system galactitol-specific IIB component
CWT10_RS02265	COG1349	DNA-binding transcription factor activity
CWT10_RS02270	COG1556	Lactate utilization protein
CWT10_RS02275	COG1139	Iron-sulfur cluster binding protein
CWT10_RS02280	COG0247	lactate metabolic process
CWT10_RS02300	COG1620	l-lactate permease
CWT10_RS02320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CWT10_RS02325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWT10_RS02330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWT10_RS02340	COG0247	lactate metabolic process
CWT10_RS02345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWT10_RS02355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CWT10_RS02445	COG1674	ftsk spoiiie
CWT10_RS02475	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CWT10_RS02490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWT10_RS02520	COG1879	ABC-type sugar transport system periplasmic component
CWT10_RS02525	COG1129	ABC transporter
CWT10_RS02530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS02535	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS02565	COG2188	Transcriptional regulator
CWT10_RS02580	COG3775	system Galactitol-specific IIC component
CWT10_RS02585	COG0235	Class ii aldolase
CWT10_RS02590	COG2376	Dihydroxyacetone kinase
CWT10_RS02595	COG2376	Dihydroxyacetone kinase
CWT10_RS02600	COG0667	Aldo Keto reductase
CWT10_RS02615	COG1609	Transcriptional regulator
CWT10_RS02625	COG1175	transmembrane transport
CWT10_RS02630	COG0395	ABC-type sugar transport system, permease component
CWT10_RS02635	COG1501	Belongs to the glycosyl hydrolase 31 family
CWT10_RS02680	COG1609	Transcriptional regulator
CWT10_RS02695	COG0395	ABC-type sugar transport system, permease component
CWT10_RS02705	COG1904	glucuronate isomerase
CWT10_RS02710	COG1609	Transcriptional regulator
CWT10_RS02715	COG3250	beta-galactosidase activity
CWT10_RS02720	COG2211	Major facilitator Superfamily
CWT10_RS02730	COG0673	inositol 2-dehydrogenase activity
CWT10_RS02735	COG0673	inositol 2-dehydrogenase activity
CWT10_RS02745	COG0246	Mannitol dehydrogenase
CWT10_RS02750	COG1312	Catalyzes the dehydration of D-mannonate
CWT10_RS02755	COG0800	Aldolase
CWT10_RS02760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWT10_RS02770	COG2115	Belongs to the xylose isomerase family
CWT10_RS02775	COG1070	Carbohydrate kinase
CWT10_RS02780	COG1609	Transcriptional regulator
CWT10_RS02785	COG3458	cephalosporin-C deacetylase activity
CWT10_RS02790	COG4209	transmembrane transport
CWT10_RS02795	COG0395	ABC-type sugar transport system, permease component
CWT10_RS02825	COG1609	Transcriptional regulator
CWT10_RS02835	COG1175	transmembrane transport
CWT10_RS02845	COG1063	alcohol dehydrogenase
CWT10_RS02855	COG4213	ABC transporter substrate-binding protein
CWT10_RS02865	COG4214	carbohydrate transport
CWT10_RS02870	COG1609	Transcriptional regulator
CWT10_RS02880	COG0395	ABC-type sugar transport system, permease component
CWT10_RS02895	COG1733	regulation of RNA biosynthetic process
CWT10_RS02905	COG1609	Transcriptional regulator
CWT10_RS02915	COG1175	transmembrane transport
CWT10_RS02920	COG0395	ABC-type sugar transport system, permease component
CWT10_RS02940	COG1131	(ABC) transporter
CWT10_RS02950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWT10_RS02950	COG1263	PTS System
CWT10_RS02950	COG2190	(PTS) system
CWT10_RS02960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWT10_RS02970	COG1129	ABC transporter
CWT10_RS02975	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS02980	COG1879	ABC-type sugar transport system periplasmic component
CWT10_RS02985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CWT10_RS02990	COG1082	Xylose isomerase domain protein TIM barrel
CWT10_RS02995	COG3959	Transketolase, thiamine diphosphate binding domain
CWT10_RS03000	COG3958	Transketolase
CWT10_RS03005	COG2390	Transcriptional regulator
CWT10_RS03030	COG3534	alpha-L-arabinofuranosidase
CWT10_RS03035	COG1609	Transcriptional regulator
CWT10_RS03045	COG1175	transmembrane transport
CWT10_RS03050	COG0395	ABC-type sugar transport system, permease component
CWT10_RS03065	COG1609	Transcriptional regulator
CWT10_RS03075	COG1653	transport
CWT10_RS03080	COG4209	transmembrane transport
CWT10_RS03085	COG0395	ABC-type sugar transport system, permease component
CWT10_RS03105	COG2160	L-arabinose isomerase activity
CWT10_RS03110	COG1609	Transcriptional regulator
CWT10_RS03115	COG1609	Transcriptional regulator
CWT10_RS03130	COG1175	transmembrane transport
CWT10_RS03135	COG0395	ABC-type sugar transport system, permease component
CWT10_RS03150	COG2017	converts alpha-aldose to the beta-anomer
CWT10_RS03155	COG1609	Transcriptional regulator
CWT10_RS03160	COG4213	ABC transporter substrate-binding protein
CWT10_RS03170	COG4214	carbohydrate transport
CWT10_RS03180	COG3458	cephalosporin-C deacetylase activity
CWT10_RS03190	COG1175	transmembrane transport
CWT10_RS03195	COG0395	ABC-type sugar transport system, permease component
CWT10_RS03200	COG1472	Belongs to the glycosyl hydrolase 3 family
CWT10_RS03240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWT10_RS03265	COG3507	Belongs to the glycosyl hydrolase 43 family
CWT10_RS03270	COG0395	ABC-type sugar transport system, permease component
CWT10_RS03275	COG1175	transmembrane transport
CWT10_RS03290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CWT10_RS03295	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CWT10_RS03305	COG1115	amino acid carrier protein
CWT10_RS03315	COG4948	Mandelate Racemase Muconate Lactonizing
CWT10_RS03330	COG0436	Aminotransferase
CWT10_RS03345	COG0250	Participates in transcription elongation, termination and antitermination
CWT10_RS03350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CWT10_RS03355	COG0081	regulation of translation
CWT10_RS03360	COG0515	serine threonine protein kinase
CWT10_RS03385	COG2894	cell division
CWT10_RS03415	COG2197	response regulator
CWT10_RS03505	COG2885	chlorophyll binding
CWT10_RS03550	COG2814	Major facilitator Superfamily
CWT10_RS03560	COG0393	Putative heavy-metal-binding
CWT10_RS03575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWT10_RS03580	COG2197	response regulator
CWT10_RS03590	COG0577	efflux transmembrane transporter activity
CWT10_RS03590	COG1136	(ABC) transporter
CWT10_RS03620	COG1674	ftsk spoiiie
CWT10_RS03620	COG0697	spore germination
CWT10_RS03640	COG1643	Atp-dependent helicase
CWT10_RS03650	COG0738	Major facilitator superfamily
CWT10_RS03665	COG3547	Transposase (IS116 IS110 IS902 family)
CWT10_RS03670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS03670	COG3711	transcriptional antiterminator
CWT10_RS03700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS03710	COG1842	Phage shock protein A
CWT10_RS03725	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CWT10_RS03745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWT10_RS03750	COG0084	hydrolase, TatD family'
CWT10_RS03765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CWT10_RS03770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CWT10_RS03775	COG0488	(ABC) transporter
CWT10_RS03820	COG0714	Associated with various cellular activities
CWT10_RS03830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CWT10_RS03830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWT10_RS03840	COG1309	transcriptional regulator
CWT10_RS03855	COG0438	transferase activity, transferring glycosyl groups
CWT10_RS03900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CWT10_RS03945	COG2244	polysaccharide biosynthetic process
CWT10_RS03965	COG0148	phosphopyruvate hydratase activity
CWT10_RS03985	COG0710	3-dehydroquinate dehydratase activity
CWT10_RS03990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CWT10_RS03995	COG0193	aminoacyl-tRNA hydrolase activity
CWT10_RS04000	COG2197	response regulator
CWT10_RS04005	COG4585	Histidine kinase
CWT10_RS04040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWT10_RS04045	COG0431	NADPH-dependent FMN reductase
CWT10_RS04065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWT10_RS04070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWT10_RS04080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWT10_RS04085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CWT10_RS04095	COG1722	exodeoxyribonuclease VII activity
CWT10_RS04100	COG4209	transmembrane transport
CWT10_RS04105	COG0395	ABC-type sugar transport system, permease component
CWT10_RS04120	COG1609	Transcriptional regulator
CWT10_RS04125	COG1570	exodeoxyribonuclease VII activity
CWT10_RS04130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CWT10_RS04140	COG1322	Protein conserved in bacteria
CWT10_RS04145	COG0012	GTP binding
CWT10_RS04160	COG0456	acetyltransferase
CWT10_RS04255	COG2304	oxidoreductase activity
CWT10_RS04270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWT10_RS04285	COG0076	glutamate decarboxylase activity
CWT10_RS04290	COG0531	amino acid
CWT10_RS04300	COG0546	phosphoglycolate phosphatase activity
CWT10_RS04315	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CWT10_RS04325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CWT10_RS04335	COG1362	aminopeptidase activity
CWT10_RS04340	COG1902	pentaerythritol trinitrate reductase activity
CWT10_RS04360	COG1268	BioY protein
CWT10_RS04395	COG1217	gtp-binding protein TYPA
CWT10_RS04420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS04420	COG3711	transcriptional antiterminator
CWT10_RS04430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWT10_RS04435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWT10_RS04440	COG2723	6-phospho-beta-galactosidase activity
CWT10_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
CWT10_RS04465	COG0656	L-ascorbic acid biosynthetic process
CWT10_RS04475	COG0583	DNA-binding transcription factor activity
CWT10_RS04535	COG0577	efflux transmembrane transporter activity
CWT10_RS04535	COG1136	(ABC) transporter
CWT10_RS04550	COG1045	serine acetyltransferase
CWT10_RS04560	COG1739	Uncharacterized protein family UPF0029
CWT10_RS04585	COG2040	homocysteine
CWT10_RS04590	COG0833	amino acid
CWT10_RS04600	COG0544	peptidyl-prolyl cis-trans isomerase activity
CWT10_RS04635	COG0740	serine-type endopeptidase activity
CWT10_RS04640	COG1683	Conserved Protein
CWT10_RS04645	COG2813	Specifically methylates the guanine in position
CWT10_RS04655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWT10_RS04680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CWT10_RS04690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWT10_RS04710	COG0066	3-isopropylmalate dehydratase activity
CWT10_RS04715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWT10_RS04725	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CWT10_RS04735	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWT10_RS04745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWT10_RS04750	COG1461	Dihydroxyacetone kinase
CWT10_RS04765	COG4115	mRNA cleavage
CWT10_RS04780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CWT10_RS04795	COG0571	ribonuclease III activity
CWT10_RS04800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWT10_RS04825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CWT10_RS04830	COG4988	ABC transporter
CWT10_RS04835	COG1294	oxidase, subunit
CWT10_RS04840	COG1271	oxidase subunit
CWT10_RS04845	COG1530	ribonuclease E activity
CWT10_RS04850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CWT10_RS04855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWT10_RS04860	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CWT10_RS04865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWT10_RS04870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CWT10_RS04880	COG0745	RESPONSE REGULATOR receiver
CWT10_RS04885	COG5002	protein histidine kinase activity
CWT10_RS04900	COG1132	(ABC) transporter
CWT10_RS04910	COG0438	transferase activity, transferring glycosyl groups
CWT10_RS04920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CWT10_RS04925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWT10_RS04940	COG0406	alpha-ribazole phosphatase activity
CWT10_RS04995	COG1518	maintenance of DNA repeat elements
CWT10_RS04995	COG1468	defense response to virus
CWT10_RS05005	COG0569	domain protein
CWT10_RS05005	COG2985	domain, Protein
CWT10_RS05020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CWT10_RS05030	COG0009	L-threonylcarbamoyladenylate synthase
CWT10_RS05035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWT10_RS05045	COG0356	it plays a direct role in the translocation of protons across the membrane
CWT10_RS05050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWT10_RS05060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWT10_RS05065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CWT10_RS05070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CWT10_RS05075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CWT10_RS05080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CWT10_RS05090	COG1028	Short-chain dehydrogenase reductase Sdr
CWT10_RS05095	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CWT10_RS05135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWT10_RS05135	COG1116	anion transmembrane transporter activity
CWT10_RS05140	COG3477	response to acidic pH
CWT10_RS05150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CWT10_RS05155	COG2197	response regulator
CWT10_RS05165	COG2235	arginine
CWT10_RS05170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWT10_RS05190	COG0577	efflux transmembrane transporter activity
CWT10_RS05190	COG1136	(ABC) transporter
CWT10_RS05195	COG3409	Peptidoglycan-binding domain 1 protein
CWT10_RS05215	COG4948	Mandelate Racemase Muconate Lactonizing
CWT10_RS05220	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CWT10_RS05225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWT10_RS05230	COG1309	transcriptional regulator
CWT10_RS05235	COG1131	(ABC) transporter
CWT10_RS05250	COG1169	isochorismate synthase
CWT10_RS05255	COG2226	methyltransferase
CWT10_RS05270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWT10_RS05275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWT10_RS05280	COG0649	NAD binding
CWT10_RS05290	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CWT10_RS05295	COG1034	ATP synthesis coupled electron transport
CWT10_RS05300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CWT10_RS05315	COG0713	ATP synthesis coupled electron transport
CWT10_RS05320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CWT10_RS05330	COG1007	ATP synthesis coupled electron transport
CWT10_RS05335	COG0142	geranyltranstransferase activity
CWT10_RS05350	COG0686	Belongs to the AlaDH PNT family
CWT10_RS05355	COG0501	Belongs to the peptidase M48B family
CWT10_RS05375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWT10_RS05400	COG0745	RESPONSE REGULATOR receiver
CWT10_RS05410	COG0586	Pfam SNARE associated Golgi protein
CWT10_RS05425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CWT10_RS05430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWT10_RS05435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWT10_RS05440	COG1316	TRANSCRIPTIONal
CWT10_RS05505	COG0438	transferase activity, transferring glycosyl groups
CWT10_RS05580	COG2801	Transposase and inactivated derivatives
CWT10_RS05610	COG1136	(ABC) transporter
CWT10_RS05610	COG0577	efflux transmembrane transporter activity
CWT10_RS05620	COG2197	response regulator
CWT10_RS05670	COG3754	Rhamnan synthesis protein F
CWT10_RS05675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CWT10_RS05690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CWT10_RS05695	COG1482	cell wall glycoprotein biosynthetic process
CWT10_RS05745	COG0714	Associated with various cellular activities
CWT10_RS05765	COG0745	RESPONSE REGULATOR receiver
CWT10_RS05770	COG5000	phosphorelay sensor kinase activity
CWT10_RS05770	COG5002	protein histidine kinase activity
CWT10_RS05780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CWT10_RS05790	COG0653	protein targeting
CWT10_RS05830	COG0419	ATPase involved in DNA repair
CWT10_RS05835	COG0420	3'-5' exonuclease activity
CWT10_RS05860	COG1968	undecaprenyl-diphosphatase activity
CWT10_RS05865	COG0483	inositol monophosphate 1-phosphatase activity
CWT10_RS05875	COG1136	(ABC) transporter
CWT10_RS05875	COG0577	efflux transmembrane transporter activity
CWT10_RS05885	COG2197	response regulator
CWT10_RS05905	COG0477	Major facilitator Superfamily
CWT10_RS05910	COG0800	Aldolase
CWT10_RS05920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWT10_RS05940	COG1609	Transcriptional regulator
CWT10_RS05955	COG1063	alcohol dehydrogenase
CWT10_RS05960	COG1120	ATPase activity
CWT10_RS05965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWT10_RS05970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWT10_RS05975	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWT10_RS05980	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CWT10_RS05995	COG1222	aaa ATPase
CWT10_RS06020	COG1140	nitrate reductase beta subunit
CWT10_RS06035	COG0315	cyclic pyranopterin monophosphate synthase activity
CWT10_RS06035	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWT10_RS06050	COG0315	cyclic pyranopterin monophosphate synthase activity
CWT10_RS06070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CWT10_RS06095	COG1162	GTPase activity
CWT10_RS06100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CWT10_RS06140	COG2838	Isocitrate dehydrogenase
CWT10_RS06150	COG1595	DNA-templated transcription, initiation
CWT10_RS06165	COG1131	(ABC) transporter
CWT10_RS06170	COG1309	transcriptional regulator
CWT10_RS06175	COG0395	ABC-type sugar transport system, permease component
CWT10_RS06180	COG1175	transmembrane transport
CWT10_RS06205	COG0739	heme binding
CWT10_RS06210	COG0584	glycerophosphoryl diester phosphodiesterase
CWT10_RS06215	COG2272	Belongs to the type-B carboxylesterase lipase family
CWT10_RS06240	COG0018	arginyl-trna synthetase
CWT10_RS06245	COG0019	diaminopimelate decarboxylase activity
CWT10_RS06275	COG0460	homoserine dehydrogenase
CWT10_RS06280	COG0083	homoserine kinase activity
CWT10_RS06290	COG0254	rRNA binding
CWT10_RS06295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CWT10_RS06310	COG1131	(ABC) transporter
CWT10_RS06350	COG0366	Alpha amylase catalytic
CWT10_RS06360	COG1472	Belongs to the glycosyl hydrolase 3 family
CWT10_RS06365	COG1653	transport
CWT10_RS06380	COG0366	Alpha amylase catalytic
CWT10_RS06385	COG1609	Transcriptional regulator
CWT10_RS06390	COG1501	Belongs to the glycosyl hydrolase 31 family
CWT10_RS06400	COG1940	carbohydrate kinase activity
CWT10_RS06400	COG1846	Transcriptional regulator
CWT10_RS06410	COG1175	transmembrane transport
CWT10_RS06415	COG0395	ABC-type sugar transport system, permease component
CWT10_RS06420	COG0366	Alpha amylase catalytic
CWT10_RS06435	COG1175	transmembrane transport
CWT10_RS06445	COG3537	Alpha-1,2-mannosidase
CWT10_RS06450	COG1609	Transcriptional regulator
CWT10_RS06455	COG0205	6-phosphofructokinase activity
CWT10_RS06475	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CWT10_RS06480	COG0039	L-malate dehydrogenase activity
CWT10_RS06520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWT10_RS06525	COG1349	DNA-binding transcription factor activity
CWT10_RS06530	COG1882	Formate acetyltransferase
CWT10_RS06540	COG0058	SHG alpha-glucan phosphorylase activity
CWT10_RS06550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWT10_RS06565	COG0366	Alpha amylase catalytic
CWT10_RS06580	COG2086	electron transfer activity
CWT10_RS06585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CWT10_RS06590	COG1725	Transcriptional regulator
CWT10_RS06595	COG1131	(ABC) transporter
CWT10_RS06605	COG1131	(ABC) transporter
CWT10_RS06615	COG0482	sulfurtransferase activity
CWT10_RS06650	COG3480	Lon protease (S16) C-terminal proteolytic domain
CWT10_RS06665	COG1615	UPF0182 protein
CWT10_RS06685	COG0114	fumarate hydratase activity
CWT10_RS06690	COG0346	lactoylglutathione lyase activity
CWT10_RS06715	COG1174	glycine betaine transport
CWT10_RS06730	COG1609	Transcriptional regulator
CWT10_RS06735	COG0673	inositol 2-dehydrogenase activity
CWT10_RS06745	COG2814	Major facilitator Superfamily
CWT10_RS06755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CWT10_RS06785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWT10_RS06795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWT10_RS06800	COG0154	amidase activity
CWT10_RS06805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWT10_RS06835	COG0647	UMP catabolic process
CWT10_RS06850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CWT10_RS06855	COG0497	DNA recombination
CWT10_RS06890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CWT10_RS06935	COG0569	domain protein
CWT10_RS06940	COG0531	amino acid
CWT10_RS06945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWT10_RS06950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CWT10_RS06960	COG0674	pyruvate-flavodoxin oxidoreductase activity
CWT10_RS06965	COG1013	pyruvate-flavodoxin oxidoreductase activity
CWT10_RS06970	COG0493	'glutamate synthase
CWT10_RS06980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWT10_RS06990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CWT10_RS06995	COG1881	PFAM PEBP family protein
CWT10_RS07015	COG1435	thymidine kinase activity
CWT10_RS07035	COG0587	DNA-directed DNA polymerase activity
CWT10_RS07045	COG0676	glucose-6-phosphate 1-epimerase activity
CWT10_RS07055	COG0738	Major facilitator superfamily
CWT10_RS07065	COG0339	signal peptide processing
CWT10_RS07075	COG0667	Aldo Keto reductase
CWT10_RS07080	COG0425	Belongs to the sulfur carrier protein TusA family
CWT10_RS07085	COG2391	methyltransferase activity
CWT10_RS07095	COG1129	ABC transporter
CWT10_RS07100	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS07105	COG1879	ABC-type sugar transport system periplasmic component
CWT10_RS07110	COG1994	Peptidase M50
CWT10_RS07110	COG0517	IMP dehydrogenase activity
CWT10_RS07115	COG2814	Major facilitator Superfamily
CWT10_RS07120	COG2264	protein methyltransferase activity
CWT10_RS07130	COG1222	aaa ATPase
CWT10_RS07135	COG4122	O-methyltransferase activity
CWT10_RS07145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CWT10_RS07155	COG0107	imidazoleglycerol-phosphate synthase activity
CWT10_RS07165	COG0134	indole-3-glycerol-phosphate synthase activity
CWT10_RS07170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CWT10_RS07190	COG1120	ATPase activity
CWT10_RS07195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWT10_RS07215	COG2050	protein possibly involved in aromatic compounds catabolism
CWT10_RS07225	COG0539	negative regulation of cytoplasmic translation
CWT10_RS07235	COG2076	Multidrug Resistance protein
CWT10_RS07240	COG0237	dephospho-CoA kinase activity
CWT10_RS07245	COG0556	nucleotide-excision repair
CWT10_RS07275	COG1136	(ABC) transporter
CWT10_RS07290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWT10_RS07295	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CWT10_RS07335	COG0561	phosphatase activity
CWT10_RS07340	COG0561	phosphatase activity
CWT10_RS07345	COG0322	excinuclease ABC activity
CWT10_RS07350	COG3711	transcriptional antiterminator
CWT10_RS07355	COG2190	(PTS) system
CWT10_RS07355	COG1263	PTS System
CWT10_RS07355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWT10_RS07365	COG3739	integral membrane protein
CWT10_RS07370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CWT10_RS07375	COG1660	Displays ATPase and GTPase activities
CWT10_RS07385	COG1481	regulation of sporulation
CWT10_RS07390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CWT10_RS07400	COG0149	triose-phosphate isomerase activity
CWT10_RS07405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWT10_RS07445	COG1160	GTP binding
CWT10_RS07475	COG0519	Catalyzes the synthesis of GMP from XMP
CWT10_RS07480	COG0166	Belongs to the GPI family
CWT10_RS07485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CWT10_RS07570	COG4989	oxidoreductase activity
CWT10_RS07575	COG0363	glucosamine-6-phosphate deaminase activity
CWT10_RS07590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CWT10_RS07615	COG0667	Aldo Keto reductase
CWT10_RS07620	COG0443	Heat shock 70 kDa protein
CWT10_RS07635	COG1621	beta-fructofuranosidase activity
CWT10_RS07640	COG2190	(PTS) system
CWT10_RS07640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWT10_RS07640	COG1263	PTS System
CWT10_RS07655	COG0395	ABC-type sugar transport system, permease component
CWT10_RS07665	COG1653	transport
CWT10_RS07670	COG1609	Transcriptional regulator
CWT10_RS07680	COG0205	6-phosphofructokinase activity
CWT10_RS07690	COG1216	Glycosyl transferase, family 2
CWT10_RS07705	COG0805	protein transport
CWT10_RS07710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWT10_RS07715	COG2378	regulation of single-species biofilm formation
CWT10_RS07730	COG0140	phosphoribosyl-ATP diphosphatase activity
CWT10_RS07735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CWT10_RS07740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWT10_RS07745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWT10_RS07755	COG1355	regulation of microtubule-based process
CWT10_RS07760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWT10_RS07770	COG1461	Dihydroxyacetone kinase
CWT10_RS07775	COG2376	Dihydroxyacetone kinase
CWT10_RS07785	COG4115	mRNA cleavage
CWT10_RS07795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWT10_RS07800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWT10_RS07805	COG4770	biotin carboxylase activity
CWT10_RS07810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWT10_RS07820	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWT10_RS07830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWT10_RS07835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CWT10_RS07845	COG1758	RNA polymerase activity
CWT10_RS07850	COG0194	GDP metabolic process
CWT10_RS07860	COG0284	orotidine-5'-phosphate decarboxylase activity
CWT10_RS07865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CWT10_RS07875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWT10_RS07880	COG0540	Belongs to the ATCase OTCase family
CWT10_RS07885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CWT10_RS07915	COG2814	Major facilitator Superfamily
CWT10_RS07920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWT10_RS07925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CWT10_RS07935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CWT10_RS07945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CWT10_RS07950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWT10_RS07955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWT10_RS07960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CWT10_RS07970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CWT10_RS07975	COG0730	response to heat
CWT10_RS07985	COG2409	Drug exporters of the RND superfamily
CWT10_RS07990	COG0009	L-threonylcarbamoyladenylate synthase
CWT10_RS08000	COG1063	alcohol dehydrogenase
CWT10_RS08025	COG3845	ABC transporter
CWT10_RS08045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWT10_RS08050	COG0601	transmembrane transport
CWT10_RS08055	COG4166	transmembrane transport
CWT10_RS08060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CWT10_RS08095	COG1196	nuclear chromosome segregation
CWT10_RS08110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWT10_RS08115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWT10_RS08120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWT10_RS08125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWT10_RS08135	COG2255	four-way junction helicase activity
CWT10_RS08140	COG0632	four-way junction helicase activity
CWT10_RS08145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CWT10_RS08150	COG0217	transcriptional regulatory protein
CWT10_RS08185	COG0438	transferase activity, transferring glycosyl groups
CWT10_RS08190	COG1560	Kdo2-lipid A biosynthetic process
CWT10_RS08195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWT10_RS08205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWT10_RS08275	COG1882	Formate acetyltransferase
CWT10_RS08295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CWT10_RS08300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWT10_RS08330	COG2815	serine threonine protein kinase
CWT10_RS08330	COG0515	serine threonine protein kinase
CWT10_RS08335	COG0321	lipoyl(octanoyl) transferase activity
CWT10_RS08340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CWT10_RS08360	COG0765	amino acid transport
CWT10_RS08375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CWT10_RS08380	COG0174	glutamine synthetase
CWT10_RS08385	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CWT10_RS08415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWT10_RS08530	COG0436	Aminotransferase
CWT10_RS08550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CWT10_RS08555	COG1027	Aspartate ammonia-lyase
CWT10_RS08565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWT10_RS08580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWT10_RS08600	COG0358	DNA primase activity
CWT10_RS08615	COG2182	Extracellular solute-binding protein
CWT10_RS08625	COG3833	ABC-type maltose transport systems, permease component
CWT10_RS08635	COG1609	Transcriptional regulator
CWT10_RS08655	COG0667	Aldo Keto reductase
CWT10_RS08660	COG0167	dihydroorotate dehydrogenase activity
CWT10_RS08685	COG0789	Transcriptional regulator
CWT10_RS08690	COG1131	(ABC) transporter
CWT10_RS08700	COG2151	metal-sulfur cluster biosynthetic enzyme
CWT10_RS08705	COG0822	iron-sulfur transferase activity
CWT10_RS08715	COG0396	ATPase activity
CWT10_RS08740	COG0395	ABC-type sugar transport system, permease component
CWT10_RS08755	COG1609	Transcriptional regulator
CWT10_RS08785	COG0351	phosphomethylpyrimidine kinase
CWT10_RS08790	COG0352	thiamine-phosphate diphosphorylase activity
CWT10_RS08795	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CWT10_RS08800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWT10_RS08805	COG0142	geranyltranstransferase activity
CWT10_RS08810	COG2815	serine threonine protein kinase
CWT10_RS08810	COG0515	serine threonine protein kinase
CWT10_RS08815	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CWT10_RS08820	COG0205	6-phosphofructokinase activity
CWT10_RS08830	COG2161	toxin-antitoxin pair type II binding
CWT10_RS08840	COG2814	Major facilitator Superfamily
CWT10_RS08860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWT10_RS08875	COG0488	(ABC) transporter
CWT10_RS08925	COG1119	ATPase activity
CWT10_RS08935	COG1472	Belongs to the glycosyl hydrolase 3 family
CWT10_RS08940	COG0297	glycogen (starch) synthase activity
CWT10_RS08950	COG3830	Belongs to the UPF0237 family
CWT10_RS08950	COG0560	Phosphoserine phosphatase
CWT10_RS08960	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CWT10_RS08975	COG0423	glycine-tRNA ligase activity
CWT10_RS08985	COG1122	ATPase activity
CWT10_RS08990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWT10_RS09010	COG2801	Transposase and inactivated derivatives
CWT10_RS09070	COG0535	radical SAM domain protein
CWT10_RS09080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWT10_RS09085	COG1381	Involved in DNA repair and RecF pathway recombination
CWT10_RS09090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWT10_RS09105	COG1476	TRANSCRIPTIONal
CWT10_RS09110	COG3609	addiction module antidote protein, CC2985 family
CWT10_RS09115	COG2337	Toxic component of a toxin-antitoxin (TA) module
CWT10_RS09120	COG1132	(ABC) transporter
CWT10_RS09145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CWT10_RS09205	COG0484	heat shock protein binding
CWT10_RS09210	COG1420	regulation of RNA biosynthetic process
CWT10_RS09245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CWT10_RS09255	COG0481	GTPase activity
CWT10_RS09295	COG1216	Glycosyl transferase, family 2
CWT10_RS09305	COG1472	Belongs to the glycosyl hydrolase 3 family
CWT10_RS09325	COG0133	tryptophan synthase activity
CWT10_RS09335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CWT10_RS09340	COG0512	Glutamine amidotransferase of anthranilate synthase
CWT10_RS09345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CWT10_RS09355	COG0159	tryptophan synthase activity
CWT10_RS09365	COG2855	membrane
CWT10_RS09370	COG2197	response regulator
CWT10_RS09375	COG4585	Histidine kinase
CWT10_RS09405	COG1131	(ABC) transporter
CWT10_RS09420	COG0268	Binds directly to 16S ribosomal RNA
CWT10_RS09425	COG4868	Belongs to the UPF0371 family
CWT10_RS09450	COG0433	COG0433 Predicted ATPase
CWT10_RS09455	COG0495	leucyl-tRNA aminoacylation
CWT10_RS09490	COG0733	neurotransmitter:sodium symporter activity
CWT10_RS09495	COG0813	purine-nucleoside phosphorylase activity
CWT10_RS09525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CWT10_RS09540	COG2094	Belongs to the DNA glycosylase MPG family
CWT10_RS09545	COG0165	Argininosuccinate lyase
CWT10_RS09555	COG0137	argininosuccinate synthase activity
CWT10_RS09560	COG1438	arginine binding
CWT10_RS09565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWT10_RS09570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CWT10_RS09580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CWT10_RS09590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWT10_RS09590	COG0072	phenylalanine-tRNA ligase activity
CWT10_RS09595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CWT10_RS09605	COG1131	(ABC) transporter
CWT10_RS09670	COG0714	Associated with various cellular activities
CWT10_RS09695	COG0765	amino acid transport
CWT10_RS09700	COG0765	amino acid transport
CWT10_RS09710	COG1126	abc transporter atp-binding protein
CWT10_RS09745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWT10_RS09750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CWT10_RS09755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CWT10_RS09760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CWT10_RS09770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CWT10_RS09775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CWT10_RS09785	COG0131	Imidazoleglycerol-phosphate dehydratase
CWT10_RS09810	COG5298	Protein conserved in bacteria
CWT10_RS09815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CWT10_RS09830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CWT10_RS09865	COG2501	S4 domain
CWT10_RS09875	COG0587	DNA-directed DNA polymerase activity
CWT10_RS09880	COG2153	protein acetylation
CWT10_RS09890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CWT10_RS09900	COG3599	regulation of cell shape
CWT10_RS09910	COG1799	cell septum assembly
CWT10_RS09915	COG1496	oxidoreductase activity
CWT10_RS09920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CWT10_RS09930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWT10_RS09940	COG0772	Belongs to the SEDS family
CWT10_RS09945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CWT10_RS09950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWT10_RS09960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWT10_RS09965	COG0768	penicillin binding
CWT10_RS09975	COG0275	rRNA processing
CWT10_RS09980	COG2001	Belongs to the MraZ family
CWT10_RS09990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWT10_RS10030	COG2801	Transposase and inactivated derivatives
CWT10_RS10035	COG0318	PFAM AMP-dependent synthetase and ligase
CWT10_RS10040	COG0318	PFAM AMP-dependent synthetase and ligase
CWT10_RS10050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWT10_RS10060	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CWT10_RS10065	COG0612	Peptidase, M16
CWT10_RS10070	COG1185	polyribonucleotide nucleotidyltransferase activity
CWT10_RS10075	COG1454	alcohol dehydrogenase
CWT10_RS10085	COG1136	(ABC) transporter
CWT10_RS10085	COG0577	efflux transmembrane transporter activity
CWT10_RS10100	COG2723	6-phospho-beta-galactosidase activity
CWT10_RS10115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CWT10_RS10120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CWT10_RS10140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CWT10_RS10150	COG0195	Participates in both transcription termination and antitermination
CWT10_RS10155	COG0779	Required for maturation of 30S ribosomal subunits
CWT10_RS10170	COG0442	prolyl-tRNA aminoacylation
CWT10_RS10190	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CWT10_RS10195	COG0750	zinc metalloprotease
CWT10_RS10200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CWT10_RS10210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CWT10_RS10215	COG0575	Belongs to the CDS family
CWT10_RS10220	COG0233	cytoplasmic translational termination
CWT10_RS10230	COG0602	queuosine metabolic process
CWT10_RS10235	COG1131	(ABC) transporter
CWT10_RS10250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CWT10_RS10255	COG0052	Belongs to the universal ribosomal protein uS2 family
CWT10_RS10270	COG1131	(ABC) transporter
CWT10_RS10290	COG0792	nuclease activity
CWT10_RS10300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CWT10_RS10305	COG0681	Belongs to the peptidase S26 family
CWT10_RS10320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CWT10_RS10325	COG1837	Belongs to the UPF0109 family
CWT10_RS10335	COG1115	amino acid carrier protein
CWT10_RS10355	COG1196	nuclear chromosome segregation
CWT10_RS10360	COG4152	abc transporter atp-binding protein
CWT10_RS10375	COG0105	UTP biosynthetic process
CWT10_RS10380	COG0285	dihydrofolate synthase activity
CWT10_RS10385	COG0489	protein tyrosine kinase activity
CWT10_RS10385	COG3206	protein involved in exopolysaccharide biosynthesis
CWT10_RS10410	COG0438	transferase activity, transferring glycosyl groups
CWT10_RS10415	COG1215	transferase activity, transferring glycosyl groups
CWT10_RS10420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWT10_RS10440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CWT10_RS10450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWT10_RS10455	COG0175	sulfate reduction
CWT10_RS10470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CWT10_RS10470	COG1648	precorrin-2 dehydrogenase activity
CWT10_RS10475	COG0730	response to heat
CWT10_RS10490	COG1263	PTS System
CWT10_RS10490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWT10_RS10490	COG2190	(PTS) system
CWT10_RS10495	COG0366	Alpha amylase catalytic
CWT10_RS10505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CWT10_RS10510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWT10_RS10535	COG1086	Polysaccharide biosynthesis protein
CWT10_RS10540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWT10_RS10585	COG0577	efflux transmembrane transporter activity
CWT10_RS10585	COG1136	(ABC) transporter
CWT10_RS10590	COG0287	Prephenate dehydrogenase
CWT10_RS10590	COG1605	Chorismate mutase
CWT10_RS10600	COG3547	Transposase (IS116 IS110 IS902 family)
CWT10_RS10605	COG1605	Chorismate mutase
CWT10_RS10605	COG0287	Prephenate dehydrogenase
CWT10_RS10610	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CWT10_RS10615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CWT10_RS10640	COG0577	efflux transmembrane transporter activity
CWT10_RS10640	COG1136	(ABC) transporter
CWT10_RS10660	COG3470	protein probably involved in high-affinity Fe2 transport
CWT10_RS10665	COG0672	)-iron permease
CWT10_RS10675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWT10_RS10680	COG1126	abc transporter atp-binding protein
CWT10_RS10685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWT10_RS10690	COG0765	amino acid transport
CWT10_RS10695	COG0765	amino acid transport
CWT10_RS10700	COG1252	NADH dehydrogenase
CWT10_RS10715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CWT10_RS10725	COG1396	sequence-specific DNA binding
CWT10_RS10730	COG1546	Belongs to the CinA family
CWT10_RS10730	COG1058	Belongs to the CinA family
CWT10_RS10740	COG1674	ftsk spoiiie
CWT10_RS10750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CWT10_RS10780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CWT10_RS10795	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWT10_RS10800	COG1115	amino acid carrier protein
CWT10_RS10805	COG1115	amino acid carrier protein
CWT10_RS10810	COG1115	amino acid carrier protein
CWT10_RS10815	COG1115	amino acid carrier protein
CWT10_RS10840	COG3304	Inner membrane component domain
CWT10_RS10885	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CWT10_RS10890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CWT10_RS10905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CWT10_RS10915	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CWT10_RS10940	COG0363	glucosamine-6-phosphate deaminase activity
CWT10_RS10950	COG1131	(ABC) transporter
CWT10_RS10960	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CWT10_RS10970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWT10_RS10975	COG4608	Belongs to the ABC transporter superfamily
CWT10_RS10980	COG0444	Belongs to the ABC transporter superfamily
CWT10_RS10990	COG0747	negative chemotaxis
CWT10_RS10995	COG2186	Transcriptional regulator
CWT10_RS11000	COG0657	acetylesterase activity
CWT10_RS11010	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWT10_RS11075	COG0667	Aldo Keto reductase
CWT10_RS11085	COG0739	heme binding
CWT10_RS11090	COG2177	Part of the ABC transporter FtsEX involved in
CWT10_RS11095	COG2884	Cell division ATP-binding protein ftsE
CWT10_RS11120	COG1716	ATPase activity
CWT10_RS11120	COG1131	(ABC) transporter
CWT10_RS11120	COG0842	Transport permease protein
CWT10_RS11145	COG0582	viral genome integration into host DNA
CWT10_RS11365	COG0791	NLP P60 protein
CWT10_RS11405	COG0582	viral genome integration into host DNA
CWT10_RS11605	COG0791	NLP P60 protein
CWT10_RS11655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWT10_RS11665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CWT10_RS11670	COG1086	Polysaccharide biosynthesis protein
CWT10_RS11675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWT10_RS11695	COG1134	teichoic acid transport
CWT10_RS11705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWT10_RS11730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CWT10_RS11735	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWT10_RS11740	COG1316	TRANSCRIPTIONal
CWT10_RS11745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWT10_RS11750	COG0473	3-isopropylmalate dehydrogenase activity
CWT10_RS11755	COG2197	response regulator
CWT10_RS11790	COG3590	peptidase
CWT10_RS11805	COG1929	Belongs to the glycerate kinase type-1 family
CWT10_RS11810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWT10_RS11815	COG1070	Carbohydrate kinase
CWT10_RS11820	COG1830	Aldolase
CWT10_RS11825	COG1063	alcohol dehydrogenase
CWT10_RS11830	COG1349	DNA-binding transcription factor activity
CWT10_RS11835	COG2271	Major facilitator Superfamily
CWT10_RS11840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWT10_RS11850	COG3618	amidohydrolase
CWT10_RS11855	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS11865	COG1879	ABC-type sugar transport system periplasmic component
CWT10_RS11885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWT10_RS11890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWT10_RS11925	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CWT10_RS11970	COG0210	DNA helicase
CWT10_RS12020	COG0513	Belongs to the DEAD box helicase family
CWT10_RS12025	COG2095	MarC family integral membrane protein
CWT10_RS12035	COG0673	inositol 2-dehydrogenase activity
CWT10_RS12040	COG0006	proline dipeptidase activity
CWT10_RS12050	COG1082	Xylose isomerase domain protein TIM barrel
CWT10_RS12060	COG2239	Acts as a magnesium transporter
CWT10_RS12075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWT10_RS12090	COG1611	Belongs to the LOG family
CWT10_RS12095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWT10_RS12110	COG1121	(ABC) transporter
CWT10_RS12115	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWT10_RS12130	COG1609	Transcriptional regulator
CWT10_RS12135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CWT10_RS12155	COG1079	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS12160	COG4603	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS12165	COG3845	ABC transporter
CWT10_RS12170	COG1744	ABC transporter substrate-binding protein PnrA-like
CWT10_RS12185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWT10_RS12195	COG0577	efflux transmembrane transporter activity
CWT10_RS12195	COG1136	(ABC) transporter
CWT10_RS12200	COG0577	efflux transmembrane transporter activity
CWT10_RS12205	COG1254	Belongs to the acylphosphatase family
CWT10_RS12220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWT10_RS12245	COG1857	crispr-associated protein
CWT10_RS12260	COG1518	maintenance of DNA repeat elements
CWT10_RS12265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWT10_RS12275	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWT10_RS12280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWT10_RS12285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWT10_RS12290	COG0254	rRNA binding
CWT10_RS12295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWT10_RS12335	COG2197	response regulator
CWT10_RS12340	COG1131	(ABC) transporter
CWT10_RS12360	COG0406	alpha-ribazole phosphatase activity
CWT10_RS12365	COG2171	N-acyltransferase activity
CWT10_RS12375	COG1053	succinate dehydrogenase
CWT10_RS12390	COG4608	Belongs to the ABC transporter superfamily
CWT10_RS12395	COG0444	Belongs to the ABC transporter superfamily
CWT10_RS12400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWT10_RS12405	COG0601	transmembrane transport
CWT10_RS12410	COG0747	negative chemotaxis
CWT10_RS12415	COG1609	Transcriptional regulator
CWT10_RS12475	COG1131	(ABC) transporter
CWT10_RS12485	COG2197	response regulator
CWT10_RS12500	COG4585	Histidine kinase
CWT10_RS12505	COG1131	(ABC) transporter
CWT10_RS12530	COG0745	RESPONSE REGULATOR receiver
CWT10_RS12535	COG2205	protein histidine kinase activity
CWT10_RS12540	COG1136	(ABC) transporter
CWT10_RS12545	COG0577	efflux transmembrane transporter activity
CWT10_RS12550	COG1609	Transcriptional regulator
CWT10_RS12555	COG1129	ABC transporter
CWT10_RS12560	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS12570	COG0488	(ABC) transporter
CWT10_RS12575	COG0667	Aldo Keto reductase
CWT10_RS12600	COG1247	-acetyltransferase
CWT10_RS12610	COG0519	Catalyzes the synthesis of GMP from XMP
CWT10_RS12635	COG0519	Catalyzes the synthesis of GMP from XMP
CWT10_RS12635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CWT10_RS12645	COG0673	inositol 2-dehydrogenase activity
CWT10_RS12650	COG1082	Xylose isomerase domain protein TIM barrel
CWT10_RS12670	COG2814	Major facilitator Superfamily
CWT10_RS12675	COG1082	Xylose isomerase domain protein TIM barrel
CWT10_RS12680	COG0673	inositol 2-dehydrogenase activity
CWT10_RS12690	COG1879	ABC-type sugar transport system periplasmic component
CWT10_RS12695	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWT10_RS12700	COG1129	ABC transporter
CWT10_RS12705	COG0673	inositol 2-dehydrogenase activity
CWT10_RS12710	COG1012	belongs to the aldehyde dehydrogenase family
CWT10_RS12715	COG3962	Belongs to the TPP enzyme family
CWT10_RS12720	COG3718	enzyme involved in inositol metabolism
CWT10_RS12730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWT10_RS12740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CWT10_RS12750	COG1609	Transcriptional regulator
CWT10_RS12770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CWT10_RS12780	COG0328	RNA-DNA hybrid ribonuclease activity
CWT10_RS12795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS12805	COG0395	ABC-type sugar transport system, permease component
CWT10_RS12820	COG0516	GMP reductase activity
CWT10_RS12840	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWT10_RS12845	COG2949	membrane
CWT10_RS12855	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CWT10_RS12860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CWT10_RS12885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CWT10_RS12890	COG1053	succinate dehydrogenase
CWT10_RS12910	COG0802	atpase or kinase
CWT10_RS12915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWT10_RS12925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWT10_RS12930	COG1072	(Pantothenic acid kinase))
CWT10_RS12945	COG1733	regulation of RNA biosynthetic process
CWT10_RS12955	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CWT10_RS12960	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CWT10_RS12970	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CWT10_RS12975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWT10_RS12980	COG0101	tRNA pseudouridine synthase activity
CWT10_RS12990	COG1136	(ABC) transporter
CWT10_RS12995	COG1940	carbohydrate kinase activity
CWT10_RS13000	COG0203	ribosomal protein L17
CWT10_RS13005	COG0202	RNA polymerase activity
CWT10_RS13010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CWT10_RS13015	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CWT10_RS13020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWT10_RS13025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWT10_RS13050	COG0563	adenylate kinase activity
CWT10_RS13070	COG1841	ribosomal large subunit assembly
CWT10_RS13075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWT10_RS13085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CWT10_RS13090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CWT10_RS13095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWT10_RS13100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CWT10_RS13105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CWT10_RS13110	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CWT10_RS13115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CWT10_RS13120	COG0255	Belongs to the universal ribosomal protein uL29 family
CWT10_RS13125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CWT10_RS13130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CWT10_RS13135	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CWT10_RS13145	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CWT10_RS13150	COG0089	rRNA binding
CWT10_RS13155	COG0088	Forms part of the polypeptide exit tunnel
CWT10_RS13160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CWT10_RS13165	COG0051	transcription antitermination factor activity, RNA binding
CWT10_RS13185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CWT10_RS13190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CWT10_RS13195	COG0049	tRNA binding
CWT10_RS13200	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CWT10_RS13220	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CWT10_RS13225	COG0085	RNA polymerase activity
CWT10_RS13230	COG0222	ribosome binding
CWT10_RS13235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CWT10_RS13240	COG2885	chlorophyll binding
CWT10_RS13305	COG1970	mechanosensitive ion channel activity
CWT10_RS13320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWT10_RS13325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS13325	COG3711	transcriptional antiterminator
CWT10_RS13330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWT10_RS13335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWT10_RS13335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWT10_RS13335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS13360	COG1388	LysM domain
CWT10_RS13360	COG3103	Sh3 type 3 domain protein
CWT10_RS13360	COG0791	NLP P60 protein
CWT10_RS13375	COG2252	PERMEase
CWT10_RS13395	COG3345	alpha-galactosidase
CWT10_RS13405	COG0395	ABC-type sugar transport system, permease component
CWT10_RS13415	COG1940	carbohydrate kinase activity
CWT10_RS13425	COG2213	PTS system mannitol-specific
CWT10_RS13430	COG1063	alcohol dehydrogenase
CWT10_RS13435	COG1061	Type III restriction enzyme res subunit
CWT10_RS13455	COG2814	Major facilitator Superfamily
CWT10_RS13465	COG1070	Carbohydrate kinase
CWT10_RS13485	COG1609	Transcriptional regulator
CWT10_RS13490	COG2211	Major facilitator Superfamily
CWT10_RS13495	COG2272	Belongs to the type-B carboxylesterase lipase family
CWT10_RS13500	COG3250	beta-galactosidase activity
CWT10_RS13540	COG3250	beta-galactosidase activity
CWT10_RS13545	COG3507	Belongs to the glycosyl hydrolase 43 family
CWT10_RS13565	COG1472	Belongs to the glycosyl hydrolase 3 family
CWT10_RS13575	COG3250	beta-galactosidase activity
CWT10_RS13580	COG4172	Belongs to the ABC transporter superfamily
CWT10_RS13595	COG0747	negative chemotaxis
CWT10_RS13620	COG3250	beta-galactosidase activity
CWT10_RS13625	COG2211	Major facilitator Superfamily
CWT10_RS13630	COG2272	Belongs to the type-B carboxylesterase lipase family
CWT10_RS13670	COG3250	beta-galactosidase activity
CWT10_RS13680	COG1131	(ABC) transporter
CWT10_RS13685	COG1132	(ABC) transporter
CWT10_RS13705	COG1131	(ABC) transporter
CWT10_RS13730	COG2723	6-phospho-beta-galactosidase activity
CWT10_RS13735	COG3250	beta-galactosidase activity
CWT10_RS13745	COG1770	oligopeptidase
CWT10_RS13810	COG2508	Transcriptional regulator
CWT10_RS13815	COG0673	inositol 2-dehydrogenase activity
CWT10_RS13825	COG2801	Transposase and inactivated derivatives
CWT10_RS13845	COG0477	Major facilitator Superfamily
CWT10_RS13850	COG0110	maltose O-acetyltransferase activity
CWT10_RS13865	COG1737	Transcriptional regulator
CWT10_RS13870	COG1263	PTS System
CWT10_RS13870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWT10_RS13870	COG2190	(PTS) system
CWT10_RS13875	COG2723	6-phospho-beta-galactosidase activity
CWT10_RS13885	COG1132	(ABC) transporter
CWT10_RS13890	COG1132	(ABC) transporter
CWT10_RS13955	COG0673	inositol 2-dehydrogenase activity
CWT10_RS13985	COG0395	ABC-type sugar transport system, permease component
CWT10_RS14015	COG1472	Belongs to the glycosyl hydrolase 3 family
CWT10_RS14020	COG2211	Major facilitator Superfamily
CWT10_RS14025	COG1940	carbohydrate kinase activity
CWT10_RS14090	COG3547	Transposase (IS116 IS110 IS902 family)
CWT10_RS14095	COG3547	Transposase (IS116 IS110 IS902 family)
CWT10_RS14105	COG1131	(ABC) transporter
CWT10_RS14145	COG1764	response to oxidative stress
CWT10_RS14155	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CWT10_RS14160	COG1329	Transcriptional regulator
CWT10_RS14170	COG5002	protein histidine kinase activity
CWT10_RS14175	COG0704	Plays a role in the regulation of phosphate uptake
CWT10_RS14180	COG0588	phosphoglycerate mutase activity
CWT10_RS14195	COG0252	asparaginase activity
CWT10_RS14210	COG0470	DNA polymerase III
CWT10_RS14215	COG1131	(ABC) transporter
CWT10_RS14225	COG1609	Transcriptional regulator
CWT10_RS14250	COG1175	transmembrane transport
CWT10_RS14255	COG0395	ABC-type sugar transport system, permease component
CWT10_RS14265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CWT10_RS14270	COG2885	chlorophyll binding
CWT10_RS14275	COG2205	protein histidine kinase activity
CWT10_RS14280	COG0745	RESPONSE REGULATOR receiver
CWT10_RS14300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWT10_RS14305	COG0549	Belongs to the carbamate kinase family
CWT10_RS14310	COG1834	amidinotransferase
CWT10_RS14325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWT10_RS14330	COG0477	Major facilitator Superfamily
CWT10_RS14345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWT10_RS14345	COG1754	DNA topoisomerase type I activity
CWT10_RS14360	COG0745	RESPONSE REGULATOR receiver
CWT10_RS14365	COG2205	protein histidine kinase activity
CWT10_RS14390	COG3547	Transposase (IS116 IS110 IS902 family)
CWT10_RS14395	COG2890	protein-(glutamine-N5) methyltransferase activity
CWT10_RS14425	COG0596	Alpha beta hydrolase
CWT10_RS14440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CWT10_RS14450	COG2801	Transposase and inactivated derivatives
CWT10_RS14455	COG1780	Probably involved in ribonucleotide reductase function
CWT10_RS14460	COG2267	carboxylic ester hydrolase activity
CWT10_RS14470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWT10_RS14485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWT10_RS14520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CWT10_RS14535	COG2261	transglycosylase associated protein
CWT10_RS14545	COG3265	gluconokinase activity
CWT10_RS14565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWT10_RS14570	COG2272	Belongs to the type-B carboxylesterase lipase family
CWT10_RS14590	COG0243	molybdopterin cofactor binding
CWT10_RS14595	COG0437	4 iron, 4 sulfur cluster binding
CWT10_RS14605	COG3381	protein complex oligomerization
CWT10_RS14640	COG1136	(ABC) transporter
CWT10_RS14650	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWT10_RS14655	COG1132	(ABC) transporter
CWT10_RS14660	COG1132	(ABC) transporter
CWT10_RS14685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CWT10_RS14695	COG4085	toxin activity
CWT10_RS14695	COG1525	nuclease
CWT10_RS14695	COG0737	Belongs to the 5'-nucleotidase family
CWT10_RS14720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWT10_RS14720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWT10_RS14720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS14730	COG1349	DNA-binding transcription factor activity
CWT10_RS14740	COG0737	Belongs to the 5'-nucleotidase family
CWT10_RS14740	COG4085	toxin activity
CWT10_RS14740	COG1525	nuclease
CWT10_RS14745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWT10_RS14760	COG2002	toxin-antitoxin pair type II binding
CWT10_RS14765	COG2610	gluconate transmembrane transporter activity
CWT10_RS14770	COG2084	Dehydrogenase
CWT10_RS14790	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
CWT10_RS14860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWT10_RS14875	COG0438	transferase activity, transferring glycosyl groups
CWT10_RS14885	COG0047	phosphoribosylformylglycinamidine synthase activity
CWT10_RS14905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CWT10_RS14915	COG0151	Belongs to the GarS family
CWT10_RS14930	COG1335	isochorismatase
CWT10_RS14935	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CWT10_RS14955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CWT10_RS14990	COG1131	(ABC) transporter
CWT10_RS15025	COG2197	response regulator
CWT10_RS15035	COG0191	fructose-bisphosphate aldolase activity
CWT10_RS15050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CWT10_RS15060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CWT10_RS15065	COG1333	cytochrome c biogenesis protein
CWT10_RS15080	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CWT10_RS15105	COG0778	Nitroreductase
CWT10_RS15110	COG2176	DNA-directed DNA polymerase activity
CWT10_RS15135	COG0717	Belongs to the dCTP deaminase family
CWT10_RS15155	COG0494	nUDIX hydrolase
CWT10_RS15190	COG0714	Associated with various cellular activities
CWT10_RS15210	COG0631	protein serine/threonine phosphatase activity
CWT10_RS15245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWT10_RS15250	COG1132	(ABC) transporter
CWT10_RS15255	COG1132	(ABC) transporter
CWT10_RS15265	COG0745	RESPONSE REGULATOR receiver
CWT10_RS15270	COG2205	protein histidine kinase activity
CWT10_RS15280	COG1136	(ABC) transporter
CWT10_RS15280	COG0577	efflux transmembrane transporter activity
CWT10_RS15285	COG1136	(ABC) transporter
CWT10_RS15330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CWT10_RS15355	COG3842	ATPase activity
CWT10_RS15375	COG1426	Protein conserved in bacteria
CWT10_RS15390	COG0395	ABC-type sugar transport system, permease component
CWT10_RS15405	COG1349	DNA-binding transcription factor activity
CWT10_RS15425	COG4133	protoheme IX ABC transporter activity
CWT10_RS15435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWT10_RS15440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CWT10_RS15460	COG0215	cysteine-tRNA ligase activity
CWT10_RS15465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CWT10_RS15470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWT10_RS15500	COG3059	membrane
CWT10_RS15530	COG3716	PTS system mannose fructose sorbose family IID component
CWT10_RS15535	COG3715	PTS system
CWT10_RS15545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS15620	COG1505	serine-type exopeptidase activity
CWT10_RS15635	COG0789	Transcriptional regulator
CWT10_RS15640	COG0484	heat shock protein binding
CWT10_RS15645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CWT10_RS15650	COG0443	Heat shock 70 kDa protein
CWT10_RS15665	COG1597	lipid kinase activity
CWT10_RS15755	COG1136	(ABC) transporter
CWT10_RS15765	COG0535	radical SAM domain protein
CWT10_RS15770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CWT10_RS15770	COG3253	May function as heme-dependent peroxidase
CWT10_RS15775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CWT10_RS15780	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CWT10_RS15785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CWT10_RS15795	COG0181	hydroxymethylbilane synthase activity
CWT10_RS15805	COG0113	porphobilinogen synthase activity
CWT10_RS15810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CWT10_RS15825	COG0783	Belongs to the Dps family
CWT10_RS15830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWT10_RS15835	COG2723	6-phospho-beta-galactosidase activity
CWT10_RS15845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWT10_RS15855	COG3711	transcriptional antiterminator
CWT10_RS15855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWT10_RS15865	COG1309	transcriptional regulator
CWT10_RS15875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWT10_RS15895	COG1131	(ABC) transporter
CWT10_RS15910	COG1137	ATPase activity
CWT10_RS15915	COG1643	Atp-dependent helicase
CWT10_RS15920	COG1438	arginine binding
CWT10_RS15935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWT10_RS15940	COG0549	Belongs to the carbamate kinase family
CWT10_RS15945	COG1438	arginine binding
CWT10_RS15955	COG0590	tRNA wobble adenosine to inosine editing
CWT10_RS15955	COG0037	tRNA processing
CWT10_RS15960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWT10_RS15965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CWT10_RS15980	COG1464	Belongs to the NlpA lipoprotein family
CWT10_RS15985	COG2011	ABC-type metal ion transport system permease component
CWT10_RS15990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWT10_RS16010	COG0667	Aldo Keto reductase
CWT10_RS16020	COG3547	Transposase (IS116 IS110 IS902 family)
CWT10_RS16025	COG1609	Transcriptional regulator
CWT10_RS16035	COG2211	Major facilitator Superfamily
CWT10_RS16045	COG3588	fructose-bisphosphate aldolase
CWT10_RS16080	COG3250	beta-galactosidase activity
CWT10_RS16105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CWT10_RS16140	COG1486	melibiose metabolic process
CWT10_RS16160	COG1175	transmembrane transport
CWT10_RS16165	COG3833	ABC-type maltose transport systems, permease component
CWT10_RS16225	COG2233	PERMEase
CWT10_RS16250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWT10_RS16300	COG0351	phosphomethylpyrimidine kinase
CWT10_RS16305	COG1695	Transcriptional regulator
CWT10_RS16310	COG1121	(ABC) transporter
CWT10_RS16320	COG0305	Participates in initiation and elongation during chromosome replication
CWT10_RS16335	COG2197	response regulator
CWT10_RS16345	COG0359	binds to the 23S rRNA
CWT10_RS16350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CWT10_RS16360	COG0360	Binds together with S18 to 16S ribosomal RNA
CWT10_RS16365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWT10_RS16370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWT10_RS16390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWT10_RS16400	COG0395	ABC-type sugar transport system, permease component
CWT10_RS16405	COG1175	transmembrane transport
CWT10_RS16410	COG1653	transport
CWT10_RS16430	COG2211	Major facilitator Superfamily
CWT10_RS16460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWT10_RS16465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CWT10_RS16475	COG1222	aaa ATPase
CWT10_RS16570	COG0492	ferredoxin-NADP+ reductase activity
CWT10_RS16575	COG3118	belongs to the thioredoxin family
CWT10_RS16605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CWT10_RS16610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWT10_RS16615	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWT10_RS16625	COG1192	Involved in chromosome partitioning
CWT10_RS16630	COG0357	Ribosomal RNA small subunit methyltransferase G
CWT10_RS16640	COG0706	membrane insertase activity
CWT10_RS16645	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CWT10_RS16650	COG0594	ribonuclease P activity
CWT10_RS16655	COG0230	Belongs to the bacterial ribosomal protein bL34 family