locus-tag	class	description
CHIBA101_RS00005	COG0592	DNA-directed DNA polymerase activity
CHIBA101_RS00010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHIBA101_RS00015	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CHIBA101_RS00020	COG0187	DNA topoisomerase II activity
CHIBA101_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHIBA101_RS00075	COG3764	Sortase (surface protein transpeptidase)
CHIBA101_RS00085	COG0515	serine threonine protein kinase
CHIBA101_RS00090	COG0768	penicillin binding
CHIBA101_RS00105	COG1716	ATPase activity
CHIBA101_RS00110	COG1716	ATPase activity
CHIBA101_RS00130	COG1966	Carbon starvation protein
CHIBA101_RS00135	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CHIBA101_RS00145	COG2197	response regulator
CHIBA101_RS00190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHIBA101_RS00195	COG1950	PFAM Membrane protein of
CHIBA101_RS00220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHIBA101_RS00250	COG3842	ATPase activity
CHIBA101_RS00255	COG1178	ABC-type Fe3 transport system permease component
CHIBA101_RS00260	COG1840	ABC-type Fe3 transport system, periplasmic component
CHIBA101_RS00270	COG5002	protein histidine kinase activity
CHIBA101_RS00275	COG3588	fructose-bisphosphate aldolase
CHIBA101_RS00315	COG1597	lipid kinase activity
CHIBA101_RS00325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHIBA101_RS00330	COG0561	phosphatase activity
CHIBA101_RS00445	COG0300	oxidoreductase activity
CHIBA101_RS00475	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHIBA101_RS00505	COG0626	cystathionine gamma-synthase activity
CHIBA101_RS00550	COG2197	response regulator
CHIBA101_RS00560	COG1131	(ABC) transporter
CHIBA101_RS00575	COG0247	lactate metabolic process
CHIBA101_RS00575	COG2181	nitrate reductase activity
CHIBA101_RS00600	COG3842	ATPase activity
CHIBA101_RS00645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHIBA101_RS00670	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CHIBA101_RS00670	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CHIBA101_RS00680	COG1733	regulation of RNA biosynthetic process
CHIBA101_RS00705	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CHIBA101_RS00720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHIBA101_RS00720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHIBA101_RS00725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHIBA101_RS00740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHIBA101_RS00755	COG2205	protein histidine kinase activity
CHIBA101_RS00770	COG1695	Transcriptional regulator
CHIBA101_RS00805	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHIBA101_RS00840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHIBA101_RS00845	COG0113	porphobilinogen synthase activity
CHIBA101_RS00855	COG0181	hydroxymethylbilane synthase activity
CHIBA101_RS00865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHIBA101_RS00870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHIBA101_RS00875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHIBA101_RS00880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHIBA101_RS00880	COG3253	May function as heme-dependent peroxidase
CHIBA101_RS00885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHIBA101_RS00890	COG0783	Belongs to the Dps family
CHIBA101_RS00905	COG1309	transcriptional regulator
CHIBA101_RS00910	COG1131	(ABC) transporter
CHIBA101_RS01010	COG1674	ftsk spoiiie
CHIBA101_RS01050	COG1051	belongs to the nudix hydrolase family
CHIBA101_RS01055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_RS01065	COG1121	(ABC) transporter
CHIBA101_RS01070	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHIBA101_RS01085	COG1918	ferrous iron import across plasma membrane
CHIBA101_RS01085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHIBA101_RS01100	COG1597	lipid kinase activity
CHIBA101_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
CHIBA101_RS01125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHIBA101_RS01155	COG0596	Alpha beta hydrolase
CHIBA101_RS01200	COG1011	Hydrolase
CHIBA101_RS01215	COG0450	alkyl hydroperoxide reductase
CHIBA101_RS01245	COG2205	protein histidine kinase activity
CHIBA101_RS01250	COG0745	RESPONSE REGULATOR receiver
CHIBA101_RS01265	COG1754	DNA topoisomerase type I activity
CHIBA101_RS01265	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHIBA101_RS01295	COG0549	Belongs to the carbamate kinase family
CHIBA101_RS01300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHIBA101_RS01305	COG2235	arginine
CHIBA101_RS01310	COG0745	RESPONSE REGULATOR receiver
CHIBA101_RS01315	COG2205	protein histidine kinase activity
CHIBA101_RS01335	COG0470	DNA polymerase III
CHIBA101_RS01355	COG0252	asparaginase activity
CHIBA101_RS01360	COG1113	amino acid transport
CHIBA101_RS01375	COG0588	phosphoglycerate mutase activity
CHIBA101_RS01385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHIBA101_RS01395	COG0393	Putative heavy-metal-binding
CHIBA101_RS01410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHIBA101_RS01420	COG1643	Atp-dependent helicase
CHIBA101_RS01420	COG1643	Atp-dependent helicase
CHIBA101_RS01445	COG3142	Participates in the control of copper homeostasis
CHIBA101_RS01450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHIBA101_RS01455	COG2860	membrane
CHIBA101_RS01490	COG0631	protein serine/threonine phosphatase activity
CHIBA101_RS01520	COG0714	Associated with various cellular activities
CHIBA101_RS01575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHIBA101_RS01595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHIBA101_RS01620	COG0717	Belongs to the dCTP deaminase family
CHIBA101_RS01635	COG2176	DNA-directed DNA polymerase activity
CHIBA101_RS01645	COG0778	Nitroreductase
CHIBA101_RS01655	COG4221	oxidoreductase activity
CHIBA101_RS01665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHIBA101_RS01670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHIBA101_RS01675	COG0191	fructose-bisphosphate aldolase activity
CHIBA101_RS01710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHIBA101_RS01725	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CHIBA101_RS01735	COG0151	Belongs to the GarS family
CHIBA101_RS01740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHIBA101_RS01755	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHIBA101_RS01760	COG0047	phosphoribosylformylglycinamidine synthase activity
CHIBA101_RS01765	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_RS01770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHIBA101_RS01805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHIBA101_RS01810	COG1349	DNA-binding transcription factor activity
CHIBA101_RS01820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHIBA101_RS01820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHIBA101_RS01835	COG2188	Transcriptional regulator
CHIBA101_RS01845	COG2084	Dehydrogenase
CHIBA101_RS01850	COG2610	gluconate transmembrane transporter activity
CHIBA101_RS01860	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHIBA101_RS01890	COG1132	(ABC) transporter
CHIBA101_RS01900	COG0577	efflux transmembrane transporter activity
CHIBA101_RS01905	COG1136	(ABC) transporter
CHIBA101_RS01920	COG1472	Belongs to the glycosyl hydrolase 3 family
CHIBA101_RS01965	COG0437	4 iron, 4 sulfur cluster binding
CHIBA101_RS01970	COG0243	molybdopterin cofactor binding
CHIBA101_RS02005	COG0513	Belongs to the DEAD box helicase family
CHIBA101_RS02015	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHIBA101_RS02035	COG1846	Transcriptional regulator
CHIBA101_RS02040	COG1764	response to oxidative stress
CHIBA101_RS02055	COG3265	gluconokinase activity
CHIBA101_RS02080	COG0306	phosphate transporter
CHIBA101_RS02090	COG0745	RESPONSE REGULATOR receiver
CHIBA101_RS02105	COG3485	protocatechuate 3,4-dioxygenase
CHIBA101_RS02120	COG1490	D-aminoacyl-tRNA deacylase activity
CHIBA101_RS02130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHIBA101_RS02130	COG1116	anion transmembrane transporter activity
CHIBA101_RS02145	COG0542	response to heat
CHIBA101_RS02160	COG0297	glycogen (starch) synthase activity
CHIBA101_RS02160	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_RS02170	COG0574	Belongs to the PEP-utilizing enzyme family
CHIBA101_RS02170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHIBA101_RS02175	COG0714	Associated with various cellular activities
CHIBA101_RS02225	COG1595	DNA-templated transcription, initiation
CHIBA101_RS02235	COG3477	response to acidic pH
CHIBA101_RS02240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CHIBA101_RS02245	COG2235	arginine
CHIBA101_RS02260	COG4948	Mandelate Racemase Muconate Lactonizing
CHIBA101_RS02265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CHIBA101_RS02270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHIBA101_RS02285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHIBA101_RS02290	COG2873	o-acetylhomoserine
CHIBA101_RS02300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CHIBA101_RS02305	COG2027	D-alanyl-D-alanine carboxypeptidase
CHIBA101_RS02315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CHIBA101_RS02320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHIBA101_RS02325	COG0302	gtp cyclohydrolase
CHIBA101_RS02335	COG2197	response regulator
CHIBA101_RS02340	COG1404	Belongs to the peptidase S8 family
CHIBA101_RS02355	COG1132	(ABC) transporter
CHIBA101_RS02390	COG1136	(ABC) transporter
CHIBA101_RS02390	COG0577	efflux transmembrane transporter activity
CHIBA101_RS02395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHIBA101_RS02400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHIBA101_RS02425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHIBA101_RS02430	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CHIBA101_RS02440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHIBA101_RS02450	COG3104	oligopeptide transport
CHIBA101_RS02465	COG2814	Major facilitator Superfamily
CHIBA101_RS02475	COG1556	Lactate utilization protein
CHIBA101_RS02480	COG1139	Iron-sulfur cluster binding protein
CHIBA101_RS02485	COG0247	lactate metabolic process
CHIBA101_RS02490	COG1620	l-lactate permease
CHIBA101_RS02495	COG2217	Heavy metal translocating P-type atpase
CHIBA101_RS02505	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHIBA101_RS02510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHIBA101_RS02515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHIBA101_RS02520	COG2390	Transcriptional regulator
CHIBA101_RS02530	COG0698	ribose 5-phosphate isomerase
CHIBA101_RS02540	COG0647	UMP catabolic process
CHIBA101_RS02545	COG1070	Carbohydrate kinase
CHIBA101_RS02560	COG2390	Transcriptional regulator
CHIBA101_RS02570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CHIBA101_RS02585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CHIBA101_RS02625	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CHIBA101_RS02640	COG2814	Major facilitator Superfamily
CHIBA101_RS02650	COG1070	Carbohydrate kinase
CHIBA101_RS02655	COG2376	Dihydroxyacetone kinase
CHIBA101_RS02660	COG1461	Dihydroxyacetone kinase
CHIBA101_RS02665	COG2017	converts alpha-aldose to the beta-anomer
CHIBA101_RS02675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHIBA101_RS02690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHIBA101_RS02695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CHIBA101_RS02710	COG0436	Aminotransferase
CHIBA101_RS02715	COG1937	Protein conserved in bacteria
CHIBA101_RS02720	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHIBA101_RS02745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHIBA101_RS02755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHIBA101_RS02760	COG0081	regulation of translation
CHIBA101_RS02765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHIBA101_RS02770	COG0222	ribosome binding
CHIBA101_RS02800	COG0085	RNA polymerase activity
CHIBA101_RS02805	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHIBA101_RS02810	COG0714	Associated with various cellular activities
CHIBA101_RS02835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHIBA101_RS02840	COG0049	tRNA binding
CHIBA101_RS02845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHIBA101_RS02850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHIBA101_RS02865	COG0051	transcription antitermination factor activity, RNA binding
CHIBA101_RS02875	COG0088	Forms part of the polypeptide exit tunnel
CHIBA101_RS02880	COG0089	rRNA binding
CHIBA101_RS02885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHIBA101_RS02890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHIBA101_RS02895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHIBA101_RS02900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHIBA101_RS02905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHIBA101_RS02910	COG0255	Belongs to the universal ribosomal protein uL29 family
CHIBA101_RS02915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHIBA101_RS02925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHIBA101_RS02930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHIBA101_RS02935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHIBA101_RS02940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHIBA101_RS02945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHIBA101_RS02950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHIBA101_RS02960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHIBA101_RS02965	COG1841	ribosomal large subunit assembly
CHIBA101_RS02970	COG0200	Binds to the 23S rRNA
CHIBA101_RS02980	COG0563	adenylate kinase activity
CHIBA101_RS02985	COG0024	Methionine aminopeptidase
CHIBA101_RS02990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHIBA101_RS02995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHIBA101_RS03000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHIBA101_RS03005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHIBA101_RS03010	COG0202	RNA polymerase activity
CHIBA101_RS03015	COG0203	ribosomal protein L17
CHIBA101_RS03035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHIBA101_RS03040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHIBA101_RS03050	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CHIBA101_RS03055	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CHIBA101_RS03060	COG1072	(Pantothenic acid kinase))
CHIBA101_RS03075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHIBA101_RS03080	COG0802	atpase or kinase
CHIBA101_RS03105	COG1053	succinate dehydrogenase
CHIBA101_RS03110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHIBA101_RS03120	COG1132	(ABC) transporter
CHIBA101_RS03120	COG2375	cellular response to nickel ion
CHIBA101_RS03125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHIBA101_RS03135	COG2949	membrane
CHIBA101_RS03140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHIBA101_RS03155	COG0516	GMP reductase activity
CHIBA101_RS03160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHIBA101_RS03165	COG0328	RNA-DNA hybrid ribonuclease activity
CHIBA101_RS03170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHIBA101_RS03185	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_RS03190	COG0673	inositol 2-dehydrogenase activity
CHIBA101_RS03195	COG1609	Transcriptional regulator
CHIBA101_RS03200	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_RS03205	COG2814	Major facilitator Superfamily
CHIBA101_RS03210	COG0673	inositol 2-dehydrogenase activity
CHIBA101_RS03215	COG1609	Transcriptional regulator
CHIBA101_RS03225	COG0673	inositol 2-dehydrogenase activity
CHIBA101_RS03230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHIBA101_RS03235	COG2188	Transcriptional regulator
CHIBA101_RS03250	COG3718	enzyme involved in inositol metabolism
CHIBA101_RS03255	COG3962	Belongs to the TPP enzyme family
CHIBA101_RS03260	COG1012	belongs to the aldehyde dehydrogenase family
CHIBA101_RS03270	COG0673	inositol 2-dehydrogenase activity
CHIBA101_RS03275	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_RS03280	COG2814	Major facilitator Superfamily
CHIBA101_RS03300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHIBA101_RS03300	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_RS03325	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_RS03340	COG0667	Aldo Keto reductase
CHIBA101_RS03380	COG2197	response regulator
CHIBA101_RS03395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHIBA101_RS03405	COG0356	it plays a direct role in the translocation of protons across the membrane
CHIBA101_RS03410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHIBA101_RS03415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHIBA101_RS03420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHIBA101_RS03425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHIBA101_RS03430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHIBA101_RS03435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHIBA101_RS03440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHIBA101_RS03465	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CHIBA101_RS03505	COG0754	glutathionylspermidine amidase activity
CHIBA101_RS03515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHIBA101_RS03520	COG0254	rRNA binding
CHIBA101_RS03525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHIBA101_RS03530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHIBA101_RS03535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHIBA101_RS03545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHIBA101_RS03550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHIBA101_RS03555	COG1254	Belongs to the acylphosphatase family
CHIBA101_RS03560	COG0708	Exodeoxyribonuclease III
CHIBA101_RS03570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CHIBA101_RS03595	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHIBA101_RS03600	COG1121	(ABC) transporter
CHIBA101_RS03605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_RS03610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_RS03610	COG1321	iron dependent repressor
CHIBA101_RS03615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHIBA101_RS03620	COG1611	Belongs to the LOG family
CHIBA101_RS03650	COG2239	Acts as a magnesium transporter
CHIBA101_RS03660	COG1230	cation diffusion facilitator family transporter
CHIBA101_RS03670	COG0006	proline dipeptidase activity
CHIBA101_RS03690	COG2095	MarC family integral membrane protein
CHIBA101_RS03695	COG0513	Belongs to the DEAD box helicase family
CHIBA101_RS03785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHIBA101_RS03800	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CHIBA101_RS03805	COG1132	(ABC) transporter
CHIBA101_RS03810	COG1132	(ABC) transporter
CHIBA101_RS03815	COG0039	L-malate dehydrogenase activity
CHIBA101_RS03830	COG1725	Transcriptional regulator
CHIBA101_RS03855	COG0058	SHG alpha-glucan phosphorylase activity
CHIBA101_RS03860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHIBA101_RS03865	COG2801	Transposase and inactivated derivatives
CHIBA101_RS03895	COG2963	transposase activity
CHIBA101_RS03905	COG2801	Transposase and inactivated derivatives
CHIBA101_RS03950	COG2801	Transposase and inactivated derivatives
CHIBA101_RS03995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHIBA101_RS04010	COG0366	Alpha amylase catalytic
CHIBA101_RS04015	COG0180	Tryptophanyl-tRNA synthetase
CHIBA101_RS04030	COG2086	electron transfer activity
CHIBA101_RS04035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHIBA101_RS04045	COG0482	sulfurtransferase activity
CHIBA101_RS04055	COG1518	maintenance of DNA repeat elements
CHIBA101_RS04070	COG1857	crispr-associated protein
CHIBA101_RS04090	COG2161	toxin-antitoxin pair type II binding
CHIBA101_RS04100	COG2390	Transcriptional regulator
CHIBA101_RS04105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHIBA101_RS04110	COG0738	Major facilitator superfamily
CHIBA101_RS04120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHIBA101_RS04140	COG1070	Carbohydrate kinase
CHIBA101_RS04160	COG1615	UPF0182 protein
CHIBA101_RS04170	COG4585	Histidine kinase
CHIBA101_RS04175	COG2197	response regulator
CHIBA101_RS04180	COG0114	fumarate hydratase activity
CHIBA101_RS04220	COG0346	lactoylglutathione lyase activity
CHIBA101_RS04230	COG1695	Transcriptional regulator
CHIBA101_RS04235	COG1125	glycine betaine transport
CHIBA101_RS04235	COG0517	IMP dehydrogenase activity
CHIBA101_RS04255	COG1609	Transcriptional regulator
CHIBA101_RS04260	COG0673	inositol 2-dehydrogenase activity
CHIBA101_RS04270	COG2814	Major facilitator Superfamily
CHIBA101_RS04280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHIBA101_RS04285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHIBA101_RS04325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHIBA101_RS04335	COG4152	abc transporter atp-binding protein
CHIBA101_RS04345	COG1196	nuclear chromosome segregation
CHIBA101_RS04385	COG1131	(ABC) transporter
CHIBA101_RS04390	COG2197	response regulator
CHIBA101_RS04395	COG3851	Histidine kinase
CHIBA101_RS04410	COG1136	(ABC) transporter
CHIBA101_RS04410	COG0577	efflux transmembrane transporter activity
CHIBA101_RS04420	COG2197	response regulator
CHIBA101_RS04425	COG0789	Transcriptional regulator
CHIBA101_RS04435	COG2197	response regulator
CHIBA101_RS04440	COG4585	Histidine kinase
CHIBA101_RS04450	COG1131	(ABC) transporter
CHIBA101_RS04455	COG1115	amino acid carrier protein
CHIBA101_RS04460	COG0228	four-way junction DNA binding
CHIBA101_RS04465	COG1837	Belongs to the UPF0109 family
CHIBA101_RS04475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHIBA101_RS04485	COG0681	Belongs to the peptidase S26 family
CHIBA101_RS04490	COG0335	large ribosomal subunit rRNA binding
CHIBA101_RS04495	COG0681	Belongs to the peptidase S26 family
CHIBA101_RS04500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHIBA101_RS04510	COG0792	nuclease activity
CHIBA101_RS04525	COG4974	Belongs to the 'phage' integrase family
CHIBA101_RS04535	COG0052	Belongs to the universal ribosomal protein uS2 family
CHIBA101_RS04540	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHIBA101_RS04560	COG0233	cytoplasmic translational termination
CHIBA101_RS04565	COG0575	Belongs to the CDS family
CHIBA101_RS04570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHIBA101_RS04580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHIBA101_RS04585	COG0750	zinc metalloprotease
CHIBA101_RS04590	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHIBA101_RS04600	COG0442	prolyl-tRNA aminoacylation
CHIBA101_RS04610	COG0779	Required for maturation of 30S ribosomal subunits
CHIBA101_RS04625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHIBA101_RS04625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHIBA101_RS04645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHIBA101_RS04650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHIBA101_RS04685	COG1472	Belongs to the glycosyl hydrolase 3 family
CHIBA101_RS04690	COG1185	polyribonucleotide nucleotidyltransferase activity
CHIBA101_RS04695	COG0612	Peptidase, M16
CHIBA101_RS04700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHIBA101_RS04720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHIBA101_RS04725	COG0656	L-ascorbic acid biosynthetic process
CHIBA101_RS04730	COG0318	PFAM AMP-dependent synthetase and ligase
CHIBA101_RS04750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHIBA101_RS04760	COG2001	Belongs to the MraZ family
CHIBA101_RS04765	COG0275	rRNA processing
CHIBA101_RS04775	COG0768	penicillin binding
CHIBA101_RS04780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHIBA101_RS04785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHIBA101_RS04790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHIBA101_RS04795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHIBA101_RS04800	COG0772	Belongs to the SEDS family
CHIBA101_RS04805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHIBA101_RS04810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHIBA101_RS04820	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHIBA101_RS04825	COG1496	oxidoreductase activity
CHIBA101_RS04830	COG1799	cell septum assembly
CHIBA101_RS04840	COG3599	regulation of cell shape
CHIBA101_RS04845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHIBA101_RS04860	COG0587	DNA-directed DNA polymerase activity
CHIBA101_RS04865	COG2501	S4 domain
CHIBA101_RS04885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHIBA101_RS04905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHIBA101_RS04935	COG0025	NhaP-type Na H and K H
CHIBA101_RS04945	COG0131	Imidazoleglycerol-phosphate dehydratase
CHIBA101_RS04960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHIBA101_RS04965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHIBA101_RS04980	COG4868	Belongs to the UPF0371 family
CHIBA101_RS04985	COG0268	Binds directly to 16S ribosomal RNA
CHIBA101_RS05000	COG0159	tryptophan synthase activity
CHIBA101_RS05010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHIBA101_RS05015	COG0512	Glutamine amidotransferase of anthranilate synthase
CHIBA101_RS05020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHIBA101_RS05025	COG0133	tryptophan synthase activity
CHIBA101_RS05035	COG0481	GTPase activity
CHIBA101_RS05045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHIBA101_RS05050	COG2807	transmembrane transport
CHIBA101_RS05060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHIBA101_RS05070	COG2271	Major facilitator Superfamily
CHIBA101_RS05080	COG1420	regulation of RNA biosynthetic process
CHIBA101_RS05085	COG0484	heat shock protein binding
CHIBA101_RS05095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHIBA101_RS05125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHIBA101_RS05135	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHIBA101_RS05150	COG1476	TRANSCRIPTIONal
CHIBA101_RS05165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHIBA101_RS05170	COG1381	Involved in DNA repair and RecF pathway recombination
CHIBA101_RS05175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHIBA101_RS05180	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CHIBA101_RS05185	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_RS05185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHIBA101_RS05190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHIBA101_RS05195	COG1121	(ABC) transporter
CHIBA101_RS05210	COG0423	glycine-tRNA ligase activity
CHIBA101_RS05245	COG0297	glycogen (starch) synthase activity
CHIBA101_RS05260	COG1119	ATPase activity
CHIBA101_RS05285	COG0488	(ABC) transporter
CHIBA101_RS05330	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHIBA101_RS05340	COG0515	serine threonine protein kinase
CHIBA101_RS05340	COG2815	serine threonine protein kinase
CHIBA101_RS05345	COG0142	geranyltranstransferase activity
CHIBA101_RS05350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHIBA101_RS05360	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CHIBA101_RS05365	COG0352	thiamine-phosphate diphosphorylase activity
CHIBA101_RS05370	COG0351	phosphomethylpyrimidine kinase
CHIBA101_RS05400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHIBA101_RS05445	COG0569	domain protein
CHIBA101_RS05450	COG0531	amino acid
CHIBA101_RS05455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHIBA101_RS05460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CHIBA101_RS05465	COG1609	Transcriptional regulator
CHIBA101_RS05485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHIBA101_RS05490	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHIBA101_RS05495	COG4221	oxidoreductase activity
CHIBA101_RS05500	COG1881	PFAM PEBP family protein
CHIBA101_RS05520	COG0833	amino acid
CHIBA101_RS05525	COG0587	DNA-directed DNA polymerase activity
CHIBA101_RS05535	COG0676	glucose-6-phosphate 1-epimerase activity
CHIBA101_RS05565	COG0477	Major facilitator Superfamily
CHIBA101_RS05575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHIBA101_RS05585	COG0667	Aldo Keto reductase
CHIBA101_RS05595	COG2391	methyltransferase activity
CHIBA101_RS05610	COG1994	Peptidase M50
CHIBA101_RS05610	COG0517	IMP dehydrogenase activity
CHIBA101_RS05615	COG2814	Major facilitator Superfamily
CHIBA101_RS05620	COG1715	Restriction endonuclease
CHIBA101_RS05630	COG1222	aaa ATPase
CHIBA101_RS05645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CHIBA101_RS05655	COG0107	imidazoleglycerol-phosphate synthase activity
CHIBA101_RS05680	COG1297	OPT oligopeptide transporter protein
CHIBA101_RS05685	COG0134	indole-3-glycerol-phosphate synthase activity
CHIBA101_RS05690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHIBA101_RS05720	COG0539	negative regulation of cytoplasmic translation
CHIBA101_RS05730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CHIBA101_RS05730	COG0237	dephospho-CoA kinase activity
CHIBA101_RS05740	COG0556	nucleotide-excision repair
CHIBA101_RS05775	COG2226	methyltransferase
CHIBA101_RS05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHIBA101_RS05800	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CHIBA101_RS05805	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CHIBA101_RS05835	COG0322	excinuclease ABC activity
CHIBA101_RS05845	COG2190	(PTS) system
CHIBA101_RS05845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_RS05845	COG1263	PTS System
CHIBA101_RS05855	COG3711	transcriptional antiterminator
CHIBA101_RS05865	COG1660	Displays ATPase and GTPase activities
CHIBA101_RS05875	COG1481	regulation of sporulation
CHIBA101_RS05880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CHIBA101_RS05885	COG0126	phosphoglycerate kinase activity
CHIBA101_RS05890	COG0149	triose-phosphate isomerase activity
CHIBA101_RS05895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHIBA101_RS05915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHIBA101_RS05930	COG1160	GTP binding
CHIBA101_RS05935	COG2818	Glycosylase
CHIBA101_RS05945	COG0166	Belongs to the GPI family
CHIBA101_RS05995	COG0657	acetylesterase activity
CHIBA101_RS06010	COG4989	oxidoreductase activity
CHIBA101_RS06030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CHIBA101_RS06040	COG1716	ATPase activity
CHIBA101_RS06060	COG0443	Heat shock 70 kDa protein
CHIBA101_RS06065	COG1263	PTS System
CHIBA101_RS06065	COG2190	(PTS) system
CHIBA101_RS06065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_RS06085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHIBA101_RS06105	COG1216	Glycosyl transferase, family 2
CHIBA101_RS06120	COG0805	protein transport
CHIBA101_RS06125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHIBA101_RS06210	COG0140	phosphoribosyl-ATP diphosphatase activity
CHIBA101_RS06215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHIBA101_RS06220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHIBA101_RS06225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHIBA101_RS06235	COG1335	isochorismatase
CHIBA101_RS06245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHIBA101_RS06250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHIBA101_RS06255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHIBA101_RS06260	COG4770	biotin carboxylase activity
CHIBA101_RS06270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHIBA101_RS06280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHIBA101_RS06300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHIBA101_RS06310	COG1758	RNA polymerase activity
CHIBA101_RS06320	COG0194	GDP metabolic process
CHIBA101_RS06330	COG0284	orotidine-5'-phosphate decarboxylase activity
CHIBA101_RS06335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHIBA101_RS06345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHIBA101_RS06350	COG0540	Belongs to the ATCase OTCase family
CHIBA101_RS06355	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CHIBA101_RS06370	COG0488	(ABC) transporter
CHIBA101_RS06385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CHIBA101_RS06395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_RS06400	COG1024	Enoyl-CoA hydratase
CHIBA101_RS06405	COG3425	synthase
CHIBA101_RS06415	COG4221	oxidoreductase activity
CHIBA101_RS06415	COG3321	synthase
CHIBA101_RS06415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_RS06415	COG0300	oxidoreductase activity
CHIBA101_RS06420	COG3321	synthase
CHIBA101_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
CHIBA101_RS06420	COG4221	oxidoreductase activity
CHIBA101_RS06420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHIBA101_RS06425	COG0300	oxidoreductase activity
CHIBA101_RS06425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_RS06425	COG4221	oxidoreductase activity
CHIBA101_RS06425	COG3321	synthase
CHIBA101_RS06425	COG0300	oxidoreductase activity
CHIBA101_RS06425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_RS06425	COG4221	oxidoreductase activity
CHIBA101_RS06425	COG3321	synthase
CHIBA101_RS06430	COG4221	oxidoreductase activity
CHIBA101_RS06430	COG3321	synthase
CHIBA101_RS06430	COG0300	oxidoreductase activity
CHIBA101_RS06430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_RS06440	COG1131	(ABC) transporter
CHIBA101_RS06445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_RS06445	COG4221	oxidoreductase activity
CHIBA101_RS06445	COG0300	oxidoreductase activity
CHIBA101_RS06445	COG3321	synthase
CHIBA101_RS06450	COG1024	Enoyl-CoA hydratase
CHIBA101_RS06475	COG0745	RESPONSE REGULATOR receiver
CHIBA101_RS06495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHIBA101_RS06500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHIBA101_RS06510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHIBA101_RS06520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHIBA101_RS06525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHIBA101_RS06535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHIBA101_RS06545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHIBA101_RS06550	COG0730	response to heat
CHIBA101_RS06560	COG2409	Drug exporters of the RND superfamily
CHIBA101_RS06565	COG0009	L-threonylcarbamoyladenylate synthase
CHIBA101_RS06570	COG0640	Transcriptional regulator
CHIBA101_RS06580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHIBA101_RS06600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHIBA101_RS06610	COG0124	histidyl-tRNA synthetase
CHIBA101_RS06630	COG1196	nuclear chromosome segregation
CHIBA101_RS06640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHIBA101_RS06645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHIBA101_RS06650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHIBA101_RS06655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHIBA101_RS06665	COG2255	four-way junction helicase activity
CHIBA101_RS06670	COG0632	four-way junction helicase activity
CHIBA101_RS06675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CHIBA101_RS06680	COG0217	transcriptional regulatory protein
CHIBA101_RS06685	COG0494	nUDIX hydrolase
CHIBA101_RS06700	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_RS06705	COG1560	Kdo2-lipid A biosynthetic process
CHIBA101_RS06710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHIBA101_RS06720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHIBA101_RS06730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHIBA101_RS06785	COG1882	Formate acetyltransferase
CHIBA101_RS06800	COG0038	chloride channel
CHIBA101_RS06810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHIBA101_RS06815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHIBA101_RS06820	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHIBA101_RS06830	COG0321	lipoyl(octanoyl) transferase activity
CHIBA101_RS06835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHIBA101_RS06855	COG0765	amino acid transport
CHIBA101_RS06870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CHIBA101_RS06875	COG0174	glutamine synthetase
CHIBA101_RS06880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHIBA101_RS06905	COG3022	response to hydroperoxide
CHIBA101_RS06915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHIBA101_RS06940	COG0436	Aminotransferase
CHIBA101_RS06970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CHIBA101_RS06975	COG1027	Aspartate ammonia-lyase
CHIBA101_RS06985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHIBA101_RS07025	COG0358	DNA primase activity
CHIBA101_RS07045	COG1175	transmembrane transport
CHIBA101_RS07050	COG3833	ABC-type maltose transport systems, permease component
CHIBA101_RS07075	COG0667	Aldo Keto reductase
CHIBA101_RS07080	COG0167	dihydroorotate dehydrogenase activity
CHIBA101_RS07095	COG0575	Belongs to the CDS family
CHIBA101_RS07105	COG3189	MarR family transcriptional regulator
CHIBA101_RS07115	COG1131	(ABC) transporter
CHIBA101_RS07130	COG2151	metal-sulfur cluster biosynthetic enzyme
CHIBA101_RS07135	COG0822	iron-sulfur transferase activity
CHIBA101_RS07145	COG0396	ATPase activity
CHIBA101_RS07155	COG0719	Fe-S assembly protein
CHIBA101_RS07170	COG0483	inositol monophosphate 1-phosphatase activity
CHIBA101_RS07195	COG1136	(ABC) transporter
CHIBA101_RS07210	COG0497	DNA recombination
CHIBA101_RS07215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHIBA101_RS07230	COG0647	UMP catabolic process
CHIBA101_RS07255	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHIBA101_RS07265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHIBA101_RS07270	COG2094	Belongs to the DNA glycosylase MPG family
CHIBA101_RS07275	COG0165	Argininosuccinate lyase
CHIBA101_RS07285	COG0137	argininosuccinate synthase activity
CHIBA101_RS07290	COG1438	arginine binding
CHIBA101_RS07295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHIBA101_RS07300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHIBA101_RS07310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHIBA101_RS07335	COG0765	amino acid transport
CHIBA101_RS07340	COG0765	amino acid transport
CHIBA101_RS07345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHIBA101_RS07350	COG1126	abc transporter atp-binding protein
CHIBA101_RS07355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHIBA101_RS07360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHIBA101_RS07365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHIBA101_RS07370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHIBA101_RS07380	COG4133	protoheme IX ABC transporter activity
CHIBA101_RS07400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHIBA101_RS07415	COG1307	EDD domain protein, DegV family
CHIBA101_RS07420	COG0433	COG0433 Predicted ATPase
CHIBA101_RS07425	COG0495	leucyl-tRNA aminoacylation
CHIBA101_RS07430	COG0537	adenosine 5'-monophosphoramidase activity
CHIBA101_RS07460	COG0733	neurotransmitter:sodium symporter activity
CHIBA101_RS07500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHIBA101_RS07505	COG1349	DNA-binding transcription factor activity
CHIBA101_RS07510	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHIBA101_RS07520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHIBA101_RS07525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHIBA101_RS07530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHIBA101_RS07535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHIBA101_RS07545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHIBA101_RS07555	COG0785	Cytochrome C biogenesis protein
CHIBA101_RS07570	COG3005	denitrification pathway
CHIBA101_RS07575	COG1530	ribonuclease E activity
CHIBA101_RS07580	COG1271	oxidase subunit
CHIBA101_RS07585	COG1294	oxidase, subunit
CHIBA101_RS07590	COG4988	ABC transporter
CHIBA101_RS07595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHIBA101_RS07610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHIBA101_RS07615	COG0571	ribonuclease III activity
CHIBA101_RS07630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHIBA101_RS07655	COG1461	Dihydroxyacetone kinase
CHIBA101_RS07660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHIBA101_RS07670	COG2885	chlorophyll binding
CHIBA101_RS07695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHIBA101_RS07705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHIBA101_RS07710	COG0066	3-isopropylmalate dehydratase activity
CHIBA101_RS07715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHIBA101_RS07735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHIBA101_RS07745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHIBA101_RS07760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHIBA101_RS07770	COG2813	Specifically methylates the guanine in position
CHIBA101_RS07780	COG1114	Component of the transport system for branched-chain amino acids
CHIBA101_RS07785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHIBA101_RS07790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHIBA101_RS07815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHIBA101_RS07820	COG1940	carbohydrate kinase activity
CHIBA101_RS07820	COG1846	Transcriptional regulator
CHIBA101_RS07830	COG1175	transmembrane transport
CHIBA101_RS07835	COG0395	ABC-type sugar transport system, permease component
CHIBA101_RS07845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHIBA101_RS07850	COG2137	regulation of response to DNA damage stimulus
CHIBA101_RS07855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHIBA101_RS07865	COG1396	sequence-specific DNA binding
CHIBA101_RS07890	COG1674	ftsk spoiiie
CHIBA101_RS07900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHIBA101_RS07945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHIBA101_RS07970	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHIBA101_RS07975	COG1115	amino acid carrier protein
CHIBA101_RS07980	COG1115	amino acid carrier protein
CHIBA101_RS07985	COG1115	amino acid carrier protein
CHIBA101_RS07990	COG1115	amino acid carrier protein
CHIBA101_RS08015	COG2040	homocysteine
CHIBA101_RS08020	COG0833	amino acid
CHIBA101_RS08025	COG3304	Inner membrane component domain
CHIBA101_RS08075	COG1126	abc transporter atp-binding protein
CHIBA101_RS08095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CHIBA101_RS08100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHIBA101_RS08110	COG1234	tRNA 3'-trailer cleavage
CHIBA101_RS08115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHIBA101_RS08125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CHIBA101_RS08145	COG0363	glucosamine-6-phosphate deaminase activity
CHIBA101_RS08155	COG1131	(ABC) transporter
CHIBA101_RS08165	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CHIBA101_RS08170	COG1940	carbohydrate kinase activity
CHIBA101_RS08180	COG4608	Belongs to the ABC transporter superfamily
CHIBA101_RS08185	COG0444	Belongs to the ABC transporter superfamily
CHIBA101_RS08195	COG4166	transmembrane transport
CHIBA101_RS08200	COG2188	Transcriptional regulator
CHIBA101_RS08205	COG2233	PERMEase
CHIBA101_RS08225	COG2177	Part of the ABC transporter FtsEX involved in
CHIBA101_RS08230	COG2884	Cell division ATP-binding protein ftsE
CHIBA101_RS08260	COG0842	Transport permease protein
CHIBA101_RS08260	COG1131	(ABC) transporter
CHIBA101_RS08260	COG1716	ATPase activity
CHIBA101_RS08265	COG0515	serine threonine protein kinase
CHIBA101_RS08270	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CHIBA101_RS08285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHIBA101_RS08290	COG1086	Polysaccharide biosynthesis protein
CHIBA101_RS08295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHIBA101_RS08340	COG1216	Glycosyl transferase, family 2
CHIBA101_RS08345	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHIBA101_RS08350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHIBA101_RS08355	COG1316	TRANSCRIPTIONal
CHIBA101_RS08360	COG0463	Glycosyl transferase, family 2
CHIBA101_RS08360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CHIBA101_RS08365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHIBA101_RS08370	COG0473	3-isopropylmalate dehydrogenase activity
CHIBA101_RS08375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHIBA101_RS08390	COG0569	domain protein
CHIBA101_RS08390	COG2985	domain, Protein
CHIBA101_RS08405	COG1609	Transcriptional regulator
CHIBA101_RS08410	COG3583	domain protein
CHIBA101_RS08410	COG1621	beta-fructofuranosidase activity
CHIBA101_RS08410	COG5492	domain, Protein
CHIBA101_RS08415	COG0395	ABC-type sugar transport system, permease component
CHIBA101_RS08420	COG1175	transmembrane transport
CHIBA101_RS08455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHIBA101_RS08460	COG0154	amidase activity
CHIBA101_RS08465	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHIBA101_RS08475	COG0105	UTP biosynthetic process
CHIBA101_RS08480	COG0285	dihydrofolate synthase activity
CHIBA101_RS08485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHIBA101_RS08490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHIBA101_RS08495	COG0489	protein tyrosine kinase activity
CHIBA101_RS08505	COG0110	maltose O-acetyltransferase activity
CHIBA101_RS08515	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_RS08525	COG1215	transferase activity, transferring glycosyl groups
CHIBA101_RS08540	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHIBA101_RS08545	COG0175	sulfate reduction
CHIBA101_RS08560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHIBA101_RS08560	COG1648	precorrin-2 dehydrogenase activity
CHIBA101_RS08565	COG0730	response to heat
CHIBA101_RS08580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHIBA101_RS08585	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CHIBA101_RS08595	COG4122	O-methyltransferase activity
CHIBA101_RS08600	COG1222	aaa ATPase
CHIBA101_RS08620	COG1605	Chorismate mutase
CHIBA101_RS08620	COG0287	Prephenate dehydrogenase
CHIBA101_RS08625	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHIBA101_RS08635	COG0740	serine-type endopeptidase activity
CHIBA101_RS08645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHIBA101_RS08670	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHIBA101_RS08695	COG0464	growth
CHIBA101_RS08705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHIBA101_RS08745	COG1201	RNA secondary structure unwinding
CHIBA101_RS08790	COG0778	Nitroreductase
CHIBA101_RS08815	COG1739	Uncharacterized protein family UPF0029
CHIBA101_RS08825	COG1045	serine acetyltransferase
CHIBA101_RS08835	COG1929	Belongs to the glycerate kinase type-1 family
CHIBA101_RS08840	COG0698	ribose 5-phosphate isomerase
CHIBA101_RS08845	COG3590	peptidase
CHIBA101_RS08865	COG2188	Transcriptional regulator
CHIBA101_RS08870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_RS08875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_RS08880	COG2190	(PTS) system
CHIBA101_RS08890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_RS08895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHIBA101_RS08900	COG1946	Acyl-CoA thioesterase
CHIBA101_RS08920	COG0045	succinate-CoA ligase (ADP-forming) activity
CHIBA101_RS08925	COG0205	6-phosphofructokinase activity
CHIBA101_RS08935	COG0366	Alpha amylase catalytic
CHIBA101_RS08945	COG2885	chlorophyll binding
CHIBA101_RS08990	COG1609	Transcriptional regulator
CHIBA101_RS08995	COG1082	Xylose isomerase domain protein TIM barrel
CHIBA101_RS09000	COG0673	inositol 2-dehydrogenase activity
CHIBA101_RS09025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHIBA101_RS09030	COG0254	rRNA binding
CHIBA101_RS09055	COG0701	Predicted permease
CHIBA101_RS09065	COG0083	homoserine kinase activity
CHIBA101_RS09070	COG0460	homoserine dehydrogenase
CHIBA101_RS09080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHIBA101_RS09085	COG0019	diaminopimelate decarboxylase activity
CHIBA101_RS09090	COG0018	arginyl-trna synthetase
CHIBA101_RS09105	COG0584	glycerophosphoryl diester phosphodiesterase
CHIBA101_RS09125	COG0567	Dehydrogenase, E1 component
CHIBA101_RS09125	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHIBA101_RS09145	COG5662	AntiSigma factor
CHIBA101_RS09150	COG1595	DNA-templated transcription, initiation
CHIBA101_RS09155	COG1695	Transcriptional regulator
CHIBA101_RS09170	COG1131	(ABC) transporter
CHIBA101_RS09190	COG2838	Isocitrate dehydrogenase
CHIBA101_RS09195	COG1487	ribonuclease activity
CHIBA101_RS09205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHIBA101_RS09210	COG1162	GTPase activity
CHIBA101_RS09215	COG0456	acetyltransferase
CHIBA101_RS09245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHIBA101_RS09255	COG0314	molybdopterin synthase activity
CHIBA101_RS09265	COG0315	cyclic pyranopterin monophosphate synthase activity
CHIBA101_RS09270	COG0746	molybdenum cofactor guanylyltransferase activity
CHIBA101_RS09275	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHIBA101_RS09275	COG0315	cyclic pyranopterin monophosphate synthase activity
CHIBA101_RS09290	COG1140	nitrate reductase beta subunit
CHIBA101_RS09295	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CHIBA101_RS09315	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_RS09320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_RS09325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHIBA101_RS09330	COG1120	ATPase activity
CHIBA101_RS09335	COG1063	alcohol dehydrogenase
CHIBA101_RS09350	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHIBA101_RS09355	COG0483	inositol monophosphate 1-phosphatase activity
CHIBA101_RS09360	COG1968	undecaprenyl-diphosphatase activity
CHIBA101_RS09365	COG0420	3'-5' exonuclease activity
CHIBA101_RS09370	COG0419	ATPase involved in DNA repair
CHIBA101_RS09375	COG1879	ABC-type sugar transport system periplasmic component
CHIBA101_RS09380	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHIBA101_RS09385	COG1129	ABC transporter
CHIBA101_RS09425	COG0653	protein targeting
CHIBA101_RS09435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHIBA101_RS09445	COG5000	phosphorelay sensor kinase activity
CHIBA101_RS09445	COG5002	protein histidine kinase activity
CHIBA101_RS09450	COG0745	RESPONSE REGULATOR receiver
CHIBA101_RS09470	COG0714	Associated with various cellular activities
CHIBA101_RS09540	COG2197	response regulator
CHIBA101_RS09570	COG1131	(ABC) transporter
CHIBA101_RS09575	COG4750	Nucleotidyl transferase
CHIBA101_RS09580	COG0697	spore germination
CHIBA101_RS09585	COG3475	LICD family
CHIBA101_RS09595	COG1215	transferase activity, transferring glycosyl groups
CHIBA101_RS09600	COG3475	LICD family
CHIBA101_RS09615	COG1216	Glycosyl transferase, family 2
CHIBA101_RS09635	COG3754	Rhamnan synthesis protein F
CHIBA101_RS09665	COG1088	dTDP-glucose 4,6-dehydratase activity
CHIBA101_RS09715	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_RS09725	COG0519	Catalyzes the synthesis of GMP from XMP
CHIBA101_RS09725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHIBA101_RS09755	COG0463	Glycosyl transferase, family 2
CHIBA101_RS09775	COG1316	TRANSCRIPTIONal
CHIBA101_RS09780	COG0395	ABC-type sugar transport system, permease component
CHIBA101_RS09785	COG1175	transmembrane transport
CHIBA101_RS09815	COG2197	response regulator
CHIBA101_RS09820	COG4585	Histidine kinase
CHIBA101_RS09825	COG1131	(ABC) transporter
CHIBA101_RS09845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHIBA101_RS09885	COG2205	protein histidine kinase activity
CHIBA101_RS09890	COG0745	RESPONSE REGULATOR receiver
CHIBA101_RS09900	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHIBA101_RS09900	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHIBA101_RS09905	COG0424	maF-like protein
CHIBA101_RS09920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHIBA101_RS09940	COG1666	GTP binding
CHIBA101_RS09950	COG0501	Belongs to the peptidase M48B family
CHIBA101_RS09965	COG1121	(ABC) transporter
CHIBA101_RS09990	COG0142	geranyltranstransferase activity
CHIBA101_RS09995	COG1007	ATP synthesis coupled electron transport
CHIBA101_RS10005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHIBA101_RS10010	COG0713	ATP synthesis coupled electron transport
CHIBA101_RS10025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHIBA101_RS10035	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CHIBA101_RS10045	COG0649	NAD binding
CHIBA101_RS10050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHIBA101_RS10055	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHIBA101_RS10065	COG0644	oxidoreductase
CHIBA101_RS10070	COG2226	methyltransferase
CHIBA101_RS10090	COG0406	alpha-ribazole phosphatase activity
CHIBA101_RS10125	COG1217	gtp-binding protein TYPA
CHIBA101_RS10135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHIBA101_RS10140	COG1268	BioY protein
CHIBA101_RS10160	COG1902	pentaerythritol trinitrate reductase activity
CHIBA101_RS10165	COG3012	SEC-C Motif Domain Protein
CHIBA101_RS10170	COG1362	aminopeptidase activity
CHIBA101_RS10175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHIBA101_RS10180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHIBA101_RS10225	COG0596	Alpha beta hydrolase
CHIBA101_RS10275	COG3422	double-strand break repair
CHIBA101_RS10305	COG1061	Type III restriction enzyme res subunit
CHIBA101_RS10315	COG0012	GTP binding
CHIBA101_RS10325	COG1322	Protein conserved in bacteria
CHIBA101_RS10330	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHIBA101_RS10335	COG1570	exodeoxyribonuclease VII activity
CHIBA101_RS10340	COG1621	beta-fructofuranosidase activity
CHIBA101_RS10345	COG1722	exodeoxyribonuclease VII activity
CHIBA101_RS10355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHIBA101_RS10365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHIBA101_RS10370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHIBA101_RS10385	COG0431	NADPH-dependent FMN reductase
CHIBA101_RS10390	COG0431	NADPH-dependent FMN reductase
CHIBA101_RS10400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHIBA101_RS10410	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHIBA101_RS10415	COG0545	Peptidyl-prolyl cis-trans isomerase
CHIBA101_RS10425	COG1131	(ABC) transporter
CHIBA101_RS10440	COG1131	(ABC) transporter
CHIBA101_RS10450	COG2197	response regulator
CHIBA101_RS10455	COG0193	aminoacyl-tRNA hydrolase activity
CHIBA101_RS10460	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHIBA101_RS10470	COG1487	ribonuclease activity
CHIBA101_RS10475	COG0710	3-dehydroquinate dehydratase activity
CHIBA101_RS10495	COG0148	phosphopyruvate hydratase activity
CHIBA101_RS10530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHIBA101_RS10600	COG0438	transferase activity, transferring glycosyl groups
CHIBA101_RS10620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CHIBA101_RS10620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHIBA101_RS10635	COG1309	transcriptional regulator
CHIBA101_RS10665	COG2815	serine threonine protein kinase
CHIBA101_RS10665	COG0515	serine threonine protein kinase
CHIBA101_RS10675	COG0488	(ABC) transporter
CHIBA101_RS10680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CHIBA101_RS10685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHIBA101_RS10695	COG1652	LysM domain
CHIBA101_RS10710	COG0084	hydrolase, TatD family'
CHIBA101_RS10715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHIBA101_RS10765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHIBA101_RS10775	COG1970	mechanosensitive ion channel activity
CHIBA101_RS10800	COG0791	NLP P60 protein
CHIBA101_RS10800	COG1388	LysM domain
CHIBA101_RS10800	COG3103	Sh3 type 3 domain protein
CHIBA101_RS10820	COG2252	PERMEase
CHIBA101_RS10845	COG1061	Type III restriction enzyme res subunit
CHIBA101_RS10865	COG1842	Phage shock protein A
CHIBA101_RS10875	COG0745	RESPONSE REGULATOR receiver
CHIBA101_RS10895	COG0459	protein refolding
CHIBA101_RS10910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHIBA101_RS10920	COG2890	protein-(glutamine-N5) methyltransferase activity
CHIBA101_RS10940	COG3842	ATPase activity
CHIBA101_RS10960	COG0215	cysteine-tRNA ligase activity
CHIBA101_RS10965	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHIBA101_RS11020	COG3716	PTS system mannose fructose sorbose family IID component
CHIBA101_RS11025	COG3715	PTS system
CHIBA101_RS11030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHIBA101_RS11030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHIBA101_RS11040	COG1621	beta-fructofuranosidase activity
CHIBA101_RS11115	COG0789	Transcriptional regulator
CHIBA101_RS11120	COG0484	heat shock protein binding
CHIBA101_RS11125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHIBA101_RS11130	COG0443	Heat shock 70 kDa protein
CHIBA101_RS11145	COG2233	PERMEase
CHIBA101_RS11165	COG1643	Atp-dependent helicase
CHIBA101_RS11175	COG0110	maltose O-acetyltransferase activity
CHIBA101_RS11185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHIBA101_RS11190	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHIBA101_RS11305	COG1464	Belongs to the NlpA lipoprotein family
CHIBA101_RS11310	COG2011	ABC-type metal ion transport system permease component
CHIBA101_RS11325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHIBA101_RS11335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHIBA101_RS11345	COG1473	amidohydrolase
CHIBA101_RS11345	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CHIBA101_RS11350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHIBA101_RS11360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHIBA101_RS11385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHIBA101_RS11390	COG2211	Major facilitator Superfamily
CHIBA101_RS11400	COG1609	Transcriptional regulator
CHIBA101_RS11405	COG0572	uridine kinase
CHIBA101_RS11430	COG0385	Bile acid
CHIBA101_RS11440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHIBA101_RS11445	COG1780	Probably involved in ribonucleotide reductase function
CHIBA101_RS11470	COG0366	Alpha amylase catalytic
CHIBA101_RS11505	COG1196	nuclear chromosome segregation
CHIBA101_RS11520	COG0628	permease
CHIBA101_RS11525	COG0596	Alpha beta hydrolase
CHIBA101_RS11530	COG1854	S-ribosylhomocysteine lyase activity
CHIBA101_RS11540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHIBA101_RS11550	COG0351	phosphomethylpyrimidine kinase
CHIBA101_RS11560	COG2985	domain, Protein
CHIBA101_RS11560	COG0569	domain protein
CHIBA101_RS11585	COG1113	amino acid transport
CHIBA101_RS11595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHIBA101_RS11600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHIBA101_RS11610	COG1940	carbohydrate kinase activity
CHIBA101_RS11620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_RS11625	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHIBA101_RS11630	COG1120	ATPase activity
CHIBA101_RS11640	COG0305	Participates in initiation and elongation during chromosome replication
CHIBA101_RS11650	COG0359	binds to the 23S rRNA
CHIBA101_RS11655	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHIBA101_RS11660	COG0629	single-stranded DNA binding
CHIBA101_RS11665	COG0360	Binds together with S18 to 16S ribosomal RNA
CHIBA101_RS11670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHIBA101_RS11685	COG1953	Uracil, thiamine, allantoin
CHIBA101_RS11690	COG3960	tartronate-semialdehyde synthase activity
CHIBA101_RS11700	COG3958	Transketolase
CHIBA101_RS11705	COG3959	Transketolase, thiamine diphosphate binding domain
CHIBA101_RS11720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHIBA101_RS11725	COG1953	Uracil, thiamine, allantoin
CHIBA101_RS11755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHIBA101_RS11765	COG3311	Transcriptional regulator
CHIBA101_RS11790	COG0617	tRNA 3'-terminal CCA addition
CHIBA101_RS11810	COG0492	ferredoxin-NADP+ reductase activity
CHIBA101_RS11815	COG3118	belongs to the thioredoxin family
CHIBA101_RS11825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHIBA101_RS11830	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHIBA101_RS11845	COG0357	Ribosomal RNA small subunit methyltransferase G
CHIBA101_RS11855	COG0706	membrane insertase activity
CHIBA101_RS11860	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHIBA101_RS11865	COG0594	ribonuclease P activity
CHIBA101_RS11870	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHIBA101_RS11875	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids