locus-tag	class	description
JJJ14_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JJJ14_RS00010	COG0592	DNA-directed DNA polymerase activity
JJJ14_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JJJ14_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JJJ14_RS00025	COG0187	DNA topoisomerase II activity
JJJ14_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JJJ14_RS00065	COG1476	TRANSCRIPTIONal
JJJ14_RS00085	COG2207	Transcriptional regulator
JJJ14_RS00120	COG3764	Sortase (surface protein transpeptidase)
JJJ14_RS00135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JJJ14_RS00140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JJJ14_RS00145	COG0360	Binds together with S18 to 16S ribosomal RNA
JJJ14_RS00155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JJJ14_RS00160	COG0359	binds to the 23S rRNA
JJJ14_RS00170	COG0534	Mate efflux family protein
JJJ14_RS00175	COG0305	Participates in initiation and elongation during chromosome replication
JJJ14_RS00185	COG1121	(ABC) transporter
JJJ14_RS00195	COG0351	phosphomethylpyrimidine kinase
JJJ14_RS00220	COG1760	l-serine dehydratase
JJJ14_RS00260	COG1780	Probably involved in ribonucleotide reductase function
JJJ14_RS00265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JJJ14_RS00280	COG0385	Bile acid
JJJ14_RS00285	COG1072	(Pantothenic acid kinase))
JJJ14_RS00335	COG1609	Transcriptional regulator
JJJ14_RS00345	COG2211	Major facilitator Superfamily
JJJ14_RS00360	COG2837	iron assimilation
JJJ14_RS00370	COG1309	transcriptional regulator
JJJ14_RS00390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JJJ14_RS00395	COG0561	phosphatase activity
JJJ14_RS00400	COG1653	transport
JJJ14_RS00450	COG0596	Alpha beta hydrolase
JJJ14_RS00455	COG0626	cystathionine gamma-synthase activity
JJJ14_RS00460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JJJ14_RS00475	COG1937	Protein conserved in bacteria
JJJ14_RS00485	COG2197	response regulator
JJJ14_RS00530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JJJ14_RS00560	COG2813	Specifically methylates the guanine in position
JJJ14_RS00580	COG1950	PFAM Membrane protein of
JJJ14_RS00585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JJJ14_RS00660	COG3739	integral membrane protein
JJJ14_RS00680	COG0463	Glycosyl transferase, family 2
JJJ14_RS00700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JJJ14_RS00715	COG2011	ABC-type metal ion transport system permease component
JJJ14_RS00720	COG1464	Belongs to the NlpA lipoprotein family
JJJ14_RS00725	COG1929	Belongs to the glycerate kinase type-1 family
JJJ14_RS00735	COG2205	protein histidine kinase activity
JJJ14_RS00760	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JJJ14_RS00765	COG2197	response regulator
JJJ14_RS00770	COG4585	Histidine kinase
JJJ14_RS00780	COG0577	efflux transmembrane transporter activity
JJJ14_RS00780	COG1136	(ABC) transporter
JJJ14_RS00790	COG0656	L-ascorbic acid biosynthetic process
JJJ14_RS00795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JJJ14_RS00800	COG0590	tRNA wobble adenosine to inosine editing
JJJ14_RS00800	COG0037	tRNA processing
JJJ14_RS00815	COG1643	Atp-dependent helicase
JJJ14_RS00850	COG0702	epimerase
JJJ14_RS00880	COG2233	PERMEase
JJJ14_RS00935	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JJJ14_RS00965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JJJ14_RS00980	COG3177	Filamentation induced by cAMP protein fic
JJJ14_RS00990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JJJ14_RS01000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JJJ14_RS01005	COG0113	porphobilinogen synthase activity
JJJ14_RS01015	COG0181	hydroxymethylbilane synthase activity
JJJ14_RS01025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JJJ14_RS01030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JJJ14_RS01035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JJJ14_RS01040	COG3253	May function as heme-dependent peroxidase
JJJ14_RS01040	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JJJ14_RS01055	COG3415	Transposase
JJJ14_RS01055	COG2801	Transposase and inactivated derivatives
JJJ14_RS01065	COG0783	Belongs to the Dps family
JJJ14_RS01120	COG1918	ferrous iron import across plasma membrane
JJJ14_RS01120	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JJJ14_RS01140	COG1597	lipid kinase activity
JJJ14_RS01165	COG1028	Short-chain dehydrogenase reductase Sdr
JJJ14_RS01170	COG1408	metallophosphoesterase
JJJ14_RS01175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JJJ14_RS01200	COG0577	efflux transmembrane transporter activity
JJJ14_RS01200	COG1136	(ABC) transporter
JJJ14_RS01210	COG2267	carboxylic ester hydrolase activity
JJJ14_RS01215	COG3548	integral membrane protein
JJJ14_RS01225	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JJJ14_RS01275	COG0450	alkyl hydroperoxide reductase
JJJ14_RS01280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JJJ14_RS01285	COG2890	protein-(glutamine-N5) methyltransferase activity
JJJ14_RS01310	COG2205	protein histidine kinase activity
JJJ14_RS01315	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS01330	COG1754	DNA topoisomerase type I activity
JJJ14_RS01330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JJJ14_RS01340	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS01345	COG0642	Histidine kinase
JJJ14_RS01350	COG2885	chlorophyll binding
JJJ14_RS01360	COG2188	Transcriptional regulator
JJJ14_RS01390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JJJ14_RS01395	COG0470	DNA polymerase III
JJJ14_RS01420	COG0252	asparaginase activity
JJJ14_RS01425	COG1113	amino acid transport
JJJ14_RS01440	COG0588	phosphoglycerate mutase activity
JJJ14_RS01450	COG5002	protein histidine kinase activity
JJJ14_RS01455	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS01465	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JJJ14_RS01495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JJJ14_RS01510	COG1643	Atp-dependent helicase
JJJ14_RS01530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JJJ14_RS01535	COG2860	membrane
JJJ14_RS01590	COG0714	Associated with various cellular activities
JJJ14_RS01650	COG0717	Belongs to the dCTP deaminase family
JJJ14_RS01660	COG2176	DNA-directed DNA polymerase activity
JJJ14_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
JJJ14_RS01680	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JJJ14_RS01685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JJJ14_RS01690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JJJ14_RS01695	COG0191	fructose-bisphosphate aldolase activity
JJJ14_RS01725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JJJ14_RS01760	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JJJ14_RS01800	COG0151	Belongs to the GarS family
JJJ14_RS01805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JJJ14_RS01825	COG0047	phosphoribosylformylglycinamidine synthase activity
JJJ14_RS01860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JJJ14_RS01890	COG1090	epimerase
JJJ14_RS01900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JJJ14_RS01905	COG4085	toxin activity
JJJ14_RS01905	COG1525	nuclease
JJJ14_RS01905	COG0737	Belongs to the 5'-nucleotidase family
JJJ14_RS01910	COG1349	DNA-binding transcription factor activity
JJJ14_RS01920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JJJ14_RS01920	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JJJ14_RS01920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JJJ14_RS01930	COG0557	exoribonuclease II activity
JJJ14_RS01935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JJJ14_RS01940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JJJ14_RS01950	COG0210	DNA helicase
JJJ14_RS01955	COG1201	RNA secondary structure unwinding
JJJ14_RS01975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JJJ14_RS02000	COG1132	(ABC) transporter
JJJ14_RS02005	COG1132	(ABC) transporter
JJJ14_RS02010	COG0577	efflux transmembrane transporter activity
JJJ14_RS02015	COG1136	(ABC) transporter
JJJ14_RS02025	COG1472	Belongs to the glycosyl hydrolase 3 family
JJJ14_RS02065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJJ14_RS02085	COG1722	exodeoxyribonuclease VII activity
JJJ14_RS02090	COG1570	exodeoxyribonuclease VII activity
JJJ14_RS02095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JJJ14_RS02100	COG0833	amino acid
JJJ14_RS02115	COG1595	DNA-templated transcription, initiation
JJJ14_RS02145	COG2261	transglycosylase associated protein
JJJ14_RS02150	COG1322	Protein conserved in bacteria
JJJ14_RS02160	COG0012	GTP binding
JJJ14_RS02165	COG1192	Involved in chromosome partitioning
JJJ14_RS02175	COG3547	Transposase (IS116 IS110 IS902 family)
JJJ14_RS02210	COG3549	Plasmid maintenance system killer
JJJ14_RS02220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JJJ14_RS02225	COG2873	o-acetylhomoserine
JJJ14_RS02235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JJJ14_RS02240	COG2027	D-alanyl-D-alanine carboxypeptidase
JJJ14_RS02250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JJJ14_RS02260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JJJ14_RS02265	COG0302	gtp cyclohydrolase
JJJ14_RS02290	COG2197	response regulator
JJJ14_RS02295	COG0577	efflux transmembrane transporter activity
JJJ14_RS02295	COG1136	(ABC) transporter
JJJ14_RS02300	COG1136	(ABC) transporter
JJJ14_RS02305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JJJ14_RS02310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JJJ14_RS02335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JJJ14_RS02340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JJJ14_RS02345	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JJJ14_RS02350	COG1917	Cupin 2, conserved barrel domain protein
JJJ14_RS02350	COG2207	Transcriptional regulator
JJJ14_RS02380	COG1136	(ABC) transporter
JJJ14_RS02390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ14_RS02395	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ14_RS02400	COG1120	ATPase activity
JJJ14_RS02405	COG4592	Periplasmic binding protein
JJJ14_RS02415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JJJ14_RS02445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JJJ14_RS02455	COG3104	oligopeptide transport
JJJ14_RS02460	COG3104	oligopeptide transport
JJJ14_RS02475	COG1556	Lactate utilization protein
JJJ14_RS02480	COG1139	Iron-sulfur cluster binding protein
JJJ14_RS02485	COG0247	lactate metabolic process
JJJ14_RS02495	COG1620	l-lactate permease
JJJ14_RS02505	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JJJ14_RS02510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JJJ14_RS02515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JJJ14_RS02520	COG2390	Transcriptional regulator
JJJ14_RS02525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JJJ14_RS02560	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JJJ14_RS02580	COG2814	Major facilitator Superfamily
JJJ14_RS02605	COG2376	Dihydroxyacetone kinase
JJJ14_RS02610	COG1461	Dihydroxyacetone kinase
JJJ14_RS02635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JJJ14_RS02650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JJJ14_RS02655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JJJ14_RS02675	COG0436	Aminotransferase
JJJ14_RS02685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JJJ14_RS02690	COG0250	Participates in transcription elongation, termination and antitermination
JJJ14_RS02695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JJJ14_RS02700	COG0081	regulation of translation
JJJ14_RS02720	COG2885	chlorophyll binding
JJJ14_RS02760	COG2197	response regulator
JJJ14_RS02765	COG4585	Histidine kinase
JJJ14_RS02790	COG2894	cell division
JJJ14_RS02815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JJJ14_RS02820	COG0049	tRNA binding
JJJ14_RS02825	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JJJ14_RS02830	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JJJ14_RS02850	COG0051	transcription antitermination factor activity, RNA binding
JJJ14_RS02865	COG0089	rRNA binding
JJJ14_RS02870	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JJJ14_RS02875	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JJJ14_RS02880	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JJJ14_RS02885	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JJJ14_RS02890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JJJ14_RS02895	COG0255	Belongs to the universal ribosomal protein uL29 family
JJJ14_RS02900	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JJJ14_RS02905	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JJJ14_RS02910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JJJ14_RS02915	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JJJ14_RS02920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JJJ14_RS02925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JJJ14_RS02930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JJJ14_RS02935	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JJJ14_RS02940	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JJJ14_RS02945	COG1841	ribosomal large subunit assembly
JJJ14_RS02960	COG0563	adenylate kinase activity
JJJ14_RS02965	COG0024	Methionine aminopeptidase
JJJ14_RS02970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JJJ14_RS02975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JJJ14_RS02980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JJJ14_RS02985	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JJJ14_RS02990	COG0202	RNA polymerase activity
JJJ14_RS02995	COG0203	ribosomal protein L17
JJJ14_RS03005	COG1285	pathogenesis
JJJ14_RS03010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JJJ14_RS03015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JJJ14_RS03025	COG0101	tRNA pseudouridine synthase activity
JJJ14_RS03030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JJJ14_RS03035	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JJJ14_RS03065	COG1396	sequence-specific DNA binding
JJJ14_RS03070	COG0596	Alpha beta hydrolase
JJJ14_RS03075	COG1072	(Pantothenic acid kinase))
JJJ14_RS03085	COG0736	holo-[acyl-carrier-protein] synthase activity
JJJ14_RS03095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JJJ14_RS03100	COG0802	atpase or kinase
JJJ14_RS03125	COG1053	succinate dehydrogenase
JJJ14_RS03130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JJJ14_RS03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JJJ14_RS03150	COG1132	(ABC) transporter
JJJ14_RS03150	COG2375	cellular response to nickel ion
JJJ14_RS03165	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JJJ14_RS03175	COG2949	membrane
JJJ14_RS03180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JJJ14_RS03200	COG0516	GMP reductase activity
JJJ14_RS03205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JJJ14_RS03210	COG4975	Glucose uptake
JJJ14_RS03230	COG0328	RNA-DNA hybrid ribonuclease activity
JJJ14_RS03240	COG2197	response regulator
JJJ14_RS03245	COG4585	Histidine kinase
JJJ14_RS03260	COG1131	(ABC) transporter
JJJ14_RS03265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JJJ14_RS03295	COG1082	Xylose isomerase domain protein TIM barrel
JJJ14_RS03300	COG2814	Major facilitator Superfamily
JJJ14_RS03305	COG0673	inositol 2-dehydrogenase activity
JJJ14_RS03315	COG2017	converts alpha-aldose to the beta-anomer
JJJ14_RS03320	COG0673	inositol 2-dehydrogenase activity
JJJ14_RS03325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JJJ14_RS03330	COG2188	Transcriptional regulator
JJJ14_RS03345	COG3718	enzyme involved in inositol metabolism
JJJ14_RS03350	COG3962	Belongs to the TPP enzyme family
JJJ14_RS03365	COG0673	inositol 2-dehydrogenase activity
JJJ14_RS03370	COG1082	Xylose isomerase domain protein TIM barrel
JJJ14_RS03375	COG2814	Major facilitator Superfamily
JJJ14_RS03400	COG0519	Catalyzes the synthesis of GMP from XMP
JJJ14_RS03400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JJJ14_RS03420	COG1131	(ABC) transporter
JJJ14_RS03425	COG4585	Histidine kinase
JJJ14_RS03465	COG2267	carboxylic ester hydrolase activity
JJJ14_RS03475	COG3654	unkown
JJJ14_RS03485	COG1401	restriction endodeoxyribonuclease activity
JJJ14_RS03490	COG4268	DNA restriction-modification system
JJJ14_RS03500	COG0693	protein deglycase activity
JJJ14_RS03520	COG2205	protein histidine kinase activity
JJJ14_RS03525	COG2197	response regulator
JJJ14_RS03535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JJJ14_RS03545	COG0356	it plays a direct role in the translocation of protons across the membrane
JJJ14_RS03555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JJJ14_RS03560	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JJJ14_RS03565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JJJ14_RS03570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JJJ14_RS03575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JJJ14_RS03580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JJJ14_RS03590	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JJJ14_RS03625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JJJ14_RS03630	COG0254	rRNA binding
JJJ14_RS03635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JJJ14_RS03640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JJJ14_RS03645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JJJ14_RS03655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JJJ14_RS03660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JJJ14_RS03665	COG1621	beta-fructofuranosidase activity
JJJ14_RS03685	COG1254	Belongs to the acylphosphatase family
JJJ14_RS03695	COG1136	(ABC) transporter
JJJ14_RS03695	COG0577	efflux transmembrane transporter activity
JJJ14_RS03700	COG1136	(ABC) transporter
JJJ14_RS03700	COG0577	efflux transmembrane transporter activity
JJJ14_RS03710	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JJJ14_RS03715	COG1349	DNA-binding transcription factor activity
JJJ14_RS03735	COG1744	ABC transporter substrate-binding protein PnrA-like
JJJ14_RS03740	COG3845	ABC transporter
JJJ14_RS03745	COG4603	Belongs to the binding-protein-dependent transport system permease family
JJJ14_RS03750	COG1079	Belongs to the binding-protein-dependent transport system permease family
JJJ14_RS03780	COG0803	Belongs to the bacterial solute-binding protein 9 family
JJJ14_RS03785	COG1121	(ABC) transporter
JJJ14_RS03800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JJJ14_RS03805	COG1611	Belongs to the LOG family
JJJ14_RS03820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JJJ14_RS03835	COG2239	Acts as a magnesium transporter
JJJ14_RS03845	COG1082	Xylose isomerase domain protein TIM barrel
JJJ14_RS03860	COG0006	proline dipeptidase activity
JJJ14_RS03865	COG0673	inositol 2-dehydrogenase activity
JJJ14_RS03870	COG0613	PHP domain protein
JJJ14_RS03875	COG2095	MarC family integral membrane protein
JJJ14_RS03880	COG0513	Belongs to the DEAD box helicase family
JJJ14_RS03925	COG0114	fumarate hydratase activity
JJJ14_RS03940	COG0346	lactoylglutathione lyase activity
JJJ14_RS03950	COG1174	glycine betaine transport
JJJ14_RS03970	COG1733	regulation of RNA biosynthetic process
JJJ14_RS03980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JJJ14_RS04010	COG1674	ftsk spoiiie
JJJ14_RS04015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JJJ14_RS04025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JJJ14_RS04030	COG0154	amidase activity
JJJ14_RS04035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JJJ14_RS04065	COG2966	Psort location CytoplasmicMembrane, score
JJJ14_RS04070	COG2985	domain, Protein
JJJ14_RS04070	COG0569	domain protein
JJJ14_RS04085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JJJ14_RS04100	COG0473	3-isopropylmalate dehydrogenase activity
JJJ14_RS04115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JJJ14_RS04120	COG1316	TRANSCRIPTIONal
JJJ14_RS04125	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JJJ14_RS04130	COG0463	Glycosyl transferase, family 2
JJJ14_RS04130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JJJ14_RS04135	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JJJ14_RS04160	COG1216	Glycosyl transferase, family 2
JJJ14_RS04170	COG1134	teichoic acid transport
JJJ14_RS04180	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS04190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JJJ14_RS04200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JJJ14_RS04215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JJJ14_RS04220	COG0515	serine threonine protein kinase
JJJ14_RS04225	COG1716	ATPase activity
JJJ14_RS04225	COG1131	(ABC) transporter
JJJ14_RS04225	COG0842	Transport permease protein
JJJ14_RS04235	COG1162	GTPase activity
JJJ14_RS04240	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JJJ14_RS04255	COG2884	Cell division ATP-binding protein ftsE
JJJ14_RS04260	COG2177	Part of the ABC transporter FtsEX involved in
JJJ14_RS04295	COG0747	negative chemotaxis
JJJ14_RS04305	COG0444	Belongs to the ABC transporter superfamily
JJJ14_RS04310	COG4608	Belongs to the ABC transporter superfamily
JJJ14_RS04325	COG1175	transmembrane transport
JJJ14_RS04335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JJJ14_RS04340	COG1940	carbohydrate kinase activity
JJJ14_RS04345	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JJJ14_RS04365	COG0363	glucosamine-6-phosphate deaminase activity
JJJ14_RS04385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JJJ14_RS04395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JJJ14_RS04415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JJJ14_RS04420	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JJJ14_RS04440	COG3415	Transposase
JJJ14_RS04440	COG2801	Transposase and inactivated derivatives
JJJ14_RS04490	COG3304	Inner membrane component domain
JJJ14_RS04495	COG0833	amino acid
JJJ14_RS04500	COG2040	homocysteine
JJJ14_RS04525	COG1115	amino acid carrier protein
JJJ14_RS04530	COG1115	amino acid carrier protein
JJJ14_RS04535	COG1115	amino acid carrier protein
JJJ14_RS04540	COG1115	amino acid carrier protein
JJJ14_RS04545	COG0179	Fumarylacetoacetate (FAA) hydrolase
JJJ14_RS04555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JJJ14_RS04585	COG0726	polysaccharide deacetylase
JJJ14_RS04590	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JJJ14_RS04600	COG1674	ftsk spoiiie
JJJ14_RS04615	COG1546	Belongs to the CinA family
JJJ14_RS04615	COG1058	Belongs to the CinA family
JJJ14_RS04620	COG1396	sequence-specific DNA binding
JJJ14_RS04630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JJJ14_RS04635	COG2137	regulation of response to DNA damage stimulus
JJJ14_RS04645	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JJJ14_RS04655	COG0395	ABC-type sugar transport system, permease component
JJJ14_RS04670	COG1846	Transcriptional regulator
JJJ14_RS04670	COG1940	carbohydrate kinase activity
JJJ14_RS04675	COG1252	NADH dehydrogenase
JJJ14_RS04680	COG0509	glycine decarboxylation via glycine cleavage system
JJJ14_RS04685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JJJ14_RS04690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JJJ14_RS04690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JJJ14_RS04695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JJJ14_RS04710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JJJ14_RS04715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JJJ14_RS04720	COG1114	Component of the transport system for branched-chain amino acids
JJJ14_RS04730	COG2813	Specifically methylates the guanine in position
JJJ14_RS04745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JJJ14_RS04760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JJJ14_RS04770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JJJ14_RS04790	COG0066	3-isopropylmalate dehydratase activity
JJJ14_RS04795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JJJ14_RS04805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JJJ14_RS04810	COG1181	Belongs to the D-alanine--D-alanine ligase family
JJJ14_RS04820	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JJJ14_RS04825	COG1461	Dihydroxyacetone kinase
JJJ14_RS04840	COG0235	Class ii aldolase
JJJ14_RS04850	COG1070	Carbohydrate kinase
JJJ14_RS04855	COG4154	Belongs to the RbsD FucU family
JJJ14_RS04860	COG0738	Major facilitator superfamily
JJJ14_RS04865	COG1609	Transcriptional regulator
JJJ14_RS04870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JJJ14_RS04885	COG0571	ribonuclease III activity
JJJ14_RS04890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JJJ14_RS04905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JJJ14_RS04910	COG4988	ABC transporter
JJJ14_RS04915	COG1294	oxidase, subunit
JJJ14_RS04920	COG1271	oxidase subunit
JJJ14_RS04925	COG1530	ribonuclease E activity
JJJ14_RS04930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JJJ14_RS04935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JJJ14_RS04940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JJJ14_RS04945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JJJ14_RS04950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JJJ14_RS04955	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JJJ14_RS04965	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS04970	COG5002	protein histidine kinase activity
JJJ14_RS04975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JJJ14_RS04990	COG1132	(ABC) transporter
JJJ14_RS04995	COG0297	glycogen (starch) synthase activity
JJJ14_RS05005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JJJ14_RS05010	COG1349	DNA-binding transcription factor activity
JJJ14_RS05020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JJJ14_RS05030	COG0799	negative regulation of ribosome biogenesis
JJJ14_RS05035	COG0406	alpha-ribazole phosphatase activity
JJJ14_RS05060	COG2801	Transposase and inactivated derivatives
JJJ14_RS05120	COG0813	purine-nucleoside phosphorylase activity
JJJ14_RS05125	COG0733	neurotransmitter:sodium symporter activity
JJJ14_RS05165	COG0537	adenosine 5'-monophosphoramidase activity
JJJ14_RS05175	COG0495	leucyl-tRNA aminoacylation
JJJ14_RS05180	COG0433	COG0433 Predicted ATPase
JJJ14_RS05185	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS05195	COG1555	photosystem II stabilization
JJJ14_RS05210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JJJ14_RS05215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JJJ14_RS05215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JJJ14_RS05230	COG4868	Belongs to the UPF0371 family
JJJ14_RS05235	COG0268	Binds directly to 16S ribosomal RNA
JJJ14_RS05240	COG1122	ATPase activity
JJJ14_RS05270	COG0159	tryptophan synthase activity
JJJ14_RS05285	COG0512	Glutamine amidotransferase of anthranilate synthase
JJJ14_RS05290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JJJ14_RS05305	COG0481	GTPase activity
JJJ14_RS05315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JJJ14_RS05320	COG2807	transmembrane transport
JJJ14_RS05335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JJJ14_RS05350	COG1420	regulation of RNA biosynthetic process
JJJ14_RS05355	COG0484	heat shock protein binding
JJJ14_RS05360	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JJJ14_RS05390	COG0842	Transport permease protein
JJJ14_RS05410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JJJ14_RS05420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JJJ14_RS05425	COG0506	proline dehydrogenase activity
JJJ14_RS05425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JJJ14_RS05425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JJJ14_RS05430	COG3609	addiction module antidote protein, CC2985 family
JJJ14_RS05435	COG2337	Toxic component of a toxin-antitoxin (TA) module
JJJ14_RS05440	COG1476	TRANSCRIPTIONal
JJJ14_RS05450	COG1131	(ABC) transporter
JJJ14_RS05455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JJJ14_RS05460	COG1381	Involved in DNA repair and RecF pathway recombination
JJJ14_RS05465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JJJ14_RS05475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JJJ14_RS05490	COG0423	glycine-tRNA ligase activity
JJJ14_RS05515	COG0560	Phosphoserine phosphatase
JJJ14_RS05525	COG0297	glycogen (starch) synthase activity
JJJ14_RS05535	COG1119	ATPase activity
JJJ14_RS05565	COG0488	(ABC) transporter
JJJ14_RS05575	COG0545	Peptidyl-prolyl cis-trans isomerase
JJJ14_RS05605	COG0205	6-phosphofructokinase activity
JJJ14_RS05610	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JJJ14_RS05615	COG0515	serine threonine protein kinase
JJJ14_RS05615	COG2815	serine threonine protein kinase
JJJ14_RS05620	COG0142	geranyltranstransferase activity
JJJ14_RS05625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JJJ14_RS05650	COG0187	DNA topoisomerase II activity
JJJ14_RS05655	COG0454	-acetyltransferase
JJJ14_RS05655	COG0456	acetyltransferase
JJJ14_RS05665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JJJ14_RS05710	COG0569	domain protein
JJJ14_RS05715	COG0531	amino acid
JJJ14_RS05720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JJJ14_RS05735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JJJ14_RS05745	COG2161	toxin-antitoxin pair type II binding
JJJ14_RS05750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJJ14_RS05765	COG4555	ABC transporter
JJJ14_RS05780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JJJ14_RS05785	COG4221	oxidoreductase activity
JJJ14_RS05790	COG1881	PFAM PEBP family protein
JJJ14_RS05805	COG0671	phosphoesterase, PA-phosphatase related
JJJ14_RS05810	COG1435	thymidine kinase activity
JJJ14_RS05830	COG0587	DNA-directed DNA polymerase activity
JJJ14_RS05875	COG0477	Major facilitator Superfamily
JJJ14_RS05885	COG0339	signal peptide processing
JJJ14_RS05890	COG0446	pyridine nucleotide-disulphide oxidoreductase
JJJ14_RS05900	COG4607	ABC-type enterochelin transport system periplasmic component
JJJ14_RS05905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ14_RS05910	COG4605	iron ion homeostasis
JJJ14_RS05915	COG4604	ABC transporter, ATP-binding protein
JJJ14_RS05920	COG0667	Aldo Keto reductase
JJJ14_RS05925	COG0425	Belongs to the sulfur carrier protein TusA family
JJJ14_RS05930	COG2391	methyltransferase activity
JJJ14_RS05940	COG0517	IMP dehydrogenase activity
JJJ14_RS05940	COG1994	Peptidase M50
JJJ14_RS05945	COG2837	iron assimilation
JJJ14_RS05960	COG1222	aaa ATPase
JJJ14_RS05965	COG4122	O-methyltransferase activity
JJJ14_RS05975	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JJJ14_RS05985	COG0107	imidazoleglycerol-phosphate synthase activity
JJJ14_RS06005	COG0134	indole-3-glycerol-phosphate synthase activity
JJJ14_RS06035	COG2050	protein possibly involved in aromatic compounds catabolism
JJJ14_RS06045	COG0539	negative regulation of cytoplasmic translation
JJJ14_RS06055	COG0237	dephospho-CoA kinase activity
JJJ14_RS06065	COG0556	nucleotide-excision repair
JJJ14_RS06125	COG0322	excinuclease ABC activity
JJJ14_RS06130	COG3585	molybdate ion transport
JJJ14_RS06140	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JJJ14_RS06145	COG1660	Displays ATPase and GTPase activities
JJJ14_RS06155	COG1481	regulation of sporulation
JJJ14_RS06160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JJJ14_RS06170	COG0149	triose-phosphate isomerase activity
JJJ14_RS06175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JJJ14_RS06195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JJJ14_RS06210	COG1160	GTP binding
JJJ14_RS06230	COG0166	Belongs to the GPI family
JJJ14_RS06235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JJJ14_RS06265	COG0363	glucosamine-6-phosphate deaminase activity
JJJ14_RS06280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JJJ14_RS06290	COG1716	ATPase activity
JJJ14_RS06310	COG0667	Aldo Keto reductase
JJJ14_RS06315	COG0443	Heat shock 70 kDa protein
JJJ14_RS06330	COG1621	beta-fructofuranosidase activity
JJJ14_RS06335	COG1263	PTS System
JJJ14_RS06335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ14_RS06335	COG2190	(PTS) system
JJJ14_RS06340	COG1609	Transcriptional regulator
JJJ14_RS06350	COG1136	(ABC) transporter
JJJ14_RS06355	COG0577	efflux transmembrane transporter activity
JJJ14_RS06370	COG0205	6-phosphofructokinase activity
JJJ14_RS06380	COG1216	Glycosyl transferase, family 2
JJJ14_RS06385	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JJJ14_RS06390	COG2354	Protein conserved in bacteria
JJJ14_RS06405	COG0805	protein transport
JJJ14_RS06410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JJJ14_RS06430	COG4585	Histidine kinase
JJJ14_RS06435	COG2197	response regulator
JJJ14_RS06440	COG1131	(ABC) transporter
JJJ14_RS06460	COG0140	phosphoribosyl-ATP diphosphatase activity
JJJ14_RS06465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JJJ14_RS06480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JJJ14_RS06485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JJJ14_RS06490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JJJ14_RS06495	COG0736	holo-[acyl-carrier-protein] synthase activity
JJJ14_RS06500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JJJ14_RS06505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JJJ14_RS06510	COG4770	biotin carboxylase activity
JJJ14_RS06515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JJJ14_RS06525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JJJ14_RS06540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JJJ14_RS06545	COG0549	Belongs to the carbamate kinase family
JJJ14_RS06560	COG0477	Major facilitator Superfamily
JJJ14_RS06575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JJJ14_RS06585	COG1758	RNA polymerase activity
JJJ14_RS06590	COG0194	GDP metabolic process
JJJ14_RS06600	COG0284	orotidine-5'-phosphate decarboxylase activity
JJJ14_RS06605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JJJ14_RS06615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JJJ14_RS06620	COG0540	Belongs to the ATCase OTCase family
JJJ14_RS06625	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JJJ14_RS06645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JJJ14_RS06650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JJJ14_RS06655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JJJ14_RS06660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JJJ14_RS06665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JJJ14_RS06670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JJJ14_RS06680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JJJ14_RS06685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JJJ14_RS06690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JJJ14_RS06700	COG0009	L-threonylcarbamoyladenylate synthase
JJJ14_RS06730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JJJ14_RS06745	COG2382	esterase
JJJ14_RS06760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JJJ14_RS06760	COG1116	anion transmembrane transporter activity
JJJ14_RS06790	COG0124	histidyl-tRNA synthetase
JJJ14_RS06805	COG1196	nuclear chromosome segregation
JJJ14_RS06810	COG0789	Transcriptional regulator
JJJ14_RS06820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JJJ14_RS06825	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JJJ14_RS06830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JJJ14_RS06835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JJJ14_RS06845	COG2255	four-way junction helicase activity
JJJ14_RS06850	COG0632	four-way junction helicase activity
JJJ14_RS06855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JJJ14_RS06860	COG0217	transcriptional regulatory protein
JJJ14_RS06865	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JJJ14_RS06870	COG1051	belongs to the nudix hydrolase family
JJJ14_RS06875	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JJJ14_RS06890	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS06910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JJJ14_RS06970	COG1882	Formate acetyltransferase
JJJ14_RS06980	COG1073	alpha beta
JJJ14_RS06985	COG0038	chloride channel
JJJ14_RS06995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JJJ14_RS07000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJJ14_RS07005	COG0508	dehydrogenase complex catalyzes the overall conversion of
JJJ14_RS07035	COG0321	lipoyl(octanoyl) transferase activity
JJJ14_RS07040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JJJ14_RS07060	COG0765	amino acid transport
JJJ14_RS07075	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JJJ14_RS07080	COG0174	glutamine synthetase
JJJ14_RS07085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JJJ14_RS07105	COG3022	response to hydroperoxide
JJJ14_RS07115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JJJ14_RS07160	COG0436	Aminotransferase
JJJ14_RS07190	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JJJ14_RS07200	COG1027	Aspartate ammonia-lyase
JJJ14_RS07210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JJJ14_RS07240	COG0358	DNA primase activity
JJJ14_RS07255	COG3415	Transposase
JJJ14_RS07255	COG2801	Transposase and inactivated derivatives
JJJ14_RS07260	COG2182	Extracellular solute-binding protein
JJJ14_RS07265	COG1175	transmembrane transport
JJJ14_RS07270	COG3833	ABC-type maltose transport systems, permease component
JJJ14_RS07275	COG1609	Transcriptional regulator
JJJ14_RS07295	COG0167	dihydroorotate dehydrogenase activity
JJJ14_RS07305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JJJ14_RS07305	COG0426	domain, Protein
JJJ14_RS07315	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JJJ14_RS07330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JJJ14_RS07345	COG3189	MarR family transcriptional regulator
JJJ14_RS07350	COG2151	metal-sulfur cluster biosynthetic enzyme
JJJ14_RS07355	COG0822	iron-sulfur transferase activity
JJJ14_RS07365	COG0396	ATPase activity
JJJ14_RS07385	COG0494	nUDIX hydrolase
JJJ14_RS07390	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS07415	COG0497	DNA recombination
JJJ14_RS07420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JJJ14_RS07435	COG0647	UMP catabolic process
JJJ14_RS07465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JJJ14_RS07485	COG2094	Belongs to the DNA glycosylase MPG family
JJJ14_RS07490	COG0165	Argininosuccinate lyase
JJJ14_RS07495	COG2116	formate transmembrane transporter activity
JJJ14_RS07500	COG0137	argininosuccinate synthase activity
JJJ14_RS07505	COG1438	arginine binding
JJJ14_RS07510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JJJ14_RS07515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JJJ14_RS07525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JJJ14_RS07540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JJJ14_RS07550	COG1131	(ABC) transporter
JJJ14_RS07570	COG0765	amino acid transport
JJJ14_RS07575	COG0765	amino acid transport
JJJ14_RS07580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JJJ14_RS07585	COG1126	abc transporter atp-binding protein
JJJ14_RS07595	COG1819	glycosyl
JJJ14_RS07600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JJJ14_RS07605	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JJJ14_RS07610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JJJ14_RS07615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JJJ14_RS07625	COG1131	(ABC) transporter
JJJ14_RS07640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JJJ14_RS07645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JJJ14_RS07660	COG0131	Imidazoleglycerol-phosphate dehydratase
JJJ14_RS07670	COG0025	NhaP-type Na H and K H
JJJ14_RS07675	COG0514	ATP-dependent DNA helicase (RecQ)
JJJ14_RS07690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JJJ14_RS07700	COG1215	transferase activity, transferring glycosyl groups
JJJ14_RS07710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JJJ14_RS07715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JJJ14_RS07735	COG2501	S4 domain
JJJ14_RS07740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JJJ14_RS07745	COG0587	DNA-directed DNA polymerase activity
JJJ14_RS07750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JJJ14_RS07765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JJJ14_RS07770	COG3599	regulation of cell shape
JJJ14_RS07780	COG1799	cell septum assembly
JJJ14_RS07785	COG1496	oxidoreductase activity
JJJ14_RS07790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JJJ14_RS07800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JJJ14_RS07815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JJJ14_RS07820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JJJ14_RS07825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JJJ14_RS07830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JJJ14_RS07835	COG0768	penicillin binding
JJJ14_RS07845	COG0275	rRNA processing
JJJ14_RS07850	COG2001	Belongs to the MraZ family
JJJ14_RS07860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JJJ14_RS07880	COG0318	PFAM AMP-dependent synthetase and ligase
JJJ14_RS07885	COG0318	PFAM AMP-dependent synthetase and ligase
JJJ14_RS07905	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JJJ14_RS07910	COG0300	oxidoreductase activity
JJJ14_RS07915	COG0612	Peptidase, M16
JJJ14_RS07920	COG1185	polyribonucleotide nucleotidyltransferase activity
JJJ14_RS07930	COG0196	riboflavin kinase activity
JJJ14_RS07940	COG1136	(ABC) transporter
JJJ14_RS07940	COG0577	efflux transmembrane transporter activity
JJJ14_RS07950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JJJ14_RS07955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JJJ14_RS07965	COG0330	HflC and HflK could
JJJ14_RS07985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JJJ14_RS08020	COG0442	prolyl-tRNA aminoacylation
JJJ14_RS08060	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JJJ14_RS08065	COG0750	zinc metalloprotease
JJJ14_RS08070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JJJ14_RS08080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JJJ14_RS08090	COG0233	cytoplasmic translational termination
JJJ14_RS08100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JJJ14_RS08105	COG0052	Belongs to the universal ribosomal protein uS2 family
JJJ14_RS08115	COG4974	Belongs to the 'phage' integrase family
JJJ14_RS08125	COG1716	ATPase activity
JJJ14_RS08145	COG0792	nuclease activity
JJJ14_RS08155	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JJJ14_RS08160	COG0681	Belongs to the peptidase S26 family
JJJ14_RS08170	COG0681	Belongs to the peptidase S26 family
JJJ14_RS08175	COG0336	Belongs to the RNA methyltransferase TrmD family
JJJ14_RS08180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JJJ14_RS08185	COG1837	Belongs to the UPF0109 family
JJJ14_RS08200	COG1131	(ABC) transporter
JJJ14_RS08210	COG4585	Histidine kinase
JJJ14_RS08215	COG2197	response regulator
JJJ14_RS08225	COG1131	(ABC) transporter
JJJ14_RS08230	COG0842	Transport permease protein
JJJ14_RS08235	COG4585	Histidine kinase
JJJ14_RS08240	COG2197	response regulator
JJJ14_RS08255	COG1196	nuclear chromosome segregation
JJJ14_RS08260	COG4152	abc transporter atp-binding protein
JJJ14_RS08270	COG0105	UTP biosynthetic process
JJJ14_RS08275	COG1461	Dihydroxyacetone kinase
JJJ14_RS08280	COG0285	dihydrofolate synthase activity
JJJ14_RS08285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JJJ14_RS08315	COG1215	transferase activity, transferring glycosyl groups
JJJ14_RS08320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JJJ14_RS08325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JJJ14_RS08345	COG2826	transposase and inactivated derivatives, IS30 family
JJJ14_RS08360	COG3415	Transposase
JJJ14_RS08360	COG2801	Transposase and inactivated derivatives
JJJ14_RS08375	COG4221	oxidoreductase activity
JJJ14_RS08380	COG2056	Na+-H+ antiporter family
JJJ14_RS08385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JJJ14_RS08390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JJJ14_RS08395	COG0175	sulfate reduction
JJJ14_RS08410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JJJ14_RS08410	COG1648	precorrin-2 dehydrogenase activity
JJJ14_RS08415	COG0730	response to heat
JJJ14_RS08445	COG2375	cellular response to nickel ion
JJJ14_RS08445	COG1132	(ABC) transporter
JJJ14_RS08450	COG1122	ATPase activity
JJJ14_RS08460	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JJJ14_RS08470	COG4122	O-methyltransferase activity
JJJ14_RS08475	COG1222	aaa ATPase
JJJ14_RS08485	COG0454	-acetyltransferase
JJJ14_RS08490	COG1609	Transcriptional regulator
JJJ14_RS08495	COG0366	Alpha amylase catalytic
JJJ14_RS08510	COG1653	transport
JJJ14_RS08525	COG0287	Prephenate dehydrogenase
JJJ14_RS08525	COG1605	Chorismate mutase
JJJ14_RS08530	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JJJ14_RS08535	COG0740	serine-type endopeptidase activity
JJJ14_RS08555	COG0544	peptidyl-prolyl cis-trans isomerase activity
JJJ14_RS08575	COG1739	Uncharacterized protein family UPF0029
JJJ14_RS08585	COG1045	serine acetyltransferase
JJJ14_RS08600	COG0698	ribose 5-phosphate isomerase
JJJ14_RS08605	COG3590	peptidase
JJJ14_RS08630	COG1263	PTS System
JJJ14_RS08635	COG2188	Transcriptional regulator
JJJ14_RS08640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ14_RS08655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ14_RS08660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JJJ14_RS08690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JJJ14_RS08760	COG0110	maltose O-acetyltransferase activity
JJJ14_RS08770	COG2326	polyphosphate kinase activity
JJJ14_RS08790	COG1615	UPF0182 protein
JJJ14_RS08805	COG3480	Lon protease (S16) C-terminal proteolytic domain
JJJ14_RS08825	COG1104	cysteine desulfurase activity
JJJ14_RS08840	COG0482	sulfurtransferase activity
JJJ14_RS08860	COG3552	Protein containing von Willebrand factor type A (VWA) domain
JJJ14_RS08870	COG0714	Associated with various cellular activities
JJJ14_RS08875	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JJJ14_RS08895	COG0366	Alpha amylase catalytic
JJJ14_RS08910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JJJ14_RS08915	COG0058	SHG alpha-glucan phosphorylase activity
JJJ14_RS08950	COG0395	ABC-type sugar transport system, permease component
JJJ14_RS08955	COG1175	transmembrane transport
JJJ14_RS08965	COG0039	L-malate dehydrogenase activity
JJJ14_RS08975	COG1132	(ABC) transporter
JJJ14_RS08980	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JJJ14_RS09015	COG0045	succinate-CoA ligase (ADP-forming) activity
JJJ14_RS09030	COG0205	6-phosphofructokinase activity
JJJ14_RS09060	COG0366	Alpha amylase catalytic
JJJ14_RS09065	COG1501	Belongs to the glycosyl hydrolase 31 family
JJJ14_RS09070	COG0110	maltose O-acetyltransferase activity
JJJ14_RS09095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JJJ14_RS09095	COG3321	synthase
JJJ14_RS09095	COG4221	oxidoreductase activity
JJJ14_RS09095	COG0604	alcohol dehydrogenase
JJJ14_RS09100	COG1846	Transcriptional regulator
JJJ14_RS09120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JJJ14_RS09125	COG0254	rRNA binding
JJJ14_RS09140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JJJ14_RS09145	COG0083	homoserine kinase activity
JJJ14_RS09150	COG0460	homoserine dehydrogenase
JJJ14_RS09165	COG0019	diaminopimelate decarboxylase activity
JJJ14_RS09170	COG0018	arginyl-trna synthetase
JJJ14_RS09195	COG0739	heme binding
JJJ14_RS09205	COG1253	flavin adenine dinucleotide binding
JJJ14_RS09210	COG0567	Dehydrogenase, E1 component
JJJ14_RS09210	COG0508	dehydrogenase complex catalyzes the overall conversion of
JJJ14_RS09230	COG1595	DNA-templated transcription, initiation
JJJ14_RS09240	COG2838	Isocitrate dehydrogenase
JJJ14_RS09245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JJJ14_RS09250	COG1162	GTPase activity
JJJ14_RS09280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JJJ14_RS09290	COG0314	molybdopterin synthase activity
JJJ14_RS09300	COG0315	cyclic pyranopterin monophosphate synthase activity
JJJ14_RS09310	COG0315	cyclic pyranopterin monophosphate synthase activity
JJJ14_RS09310	COG0521	Mo-molybdopterin cofactor biosynthetic process
JJJ14_RS09325	COG1140	nitrate reductase beta subunit
JJJ14_RS09350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JJJ14_RS09355	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ14_RS09360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ14_RS09370	COG1120	ATPase activity
JJJ14_RS09380	COG2249	NAD(P)H dehydrogenase (quinone) activity
JJJ14_RS09385	COG0456	acetyltransferase
JJJ14_RS09390	COG2249	NAD(P)H dehydrogenase (quinone) activity
JJJ14_RS09395	COG0483	inositol monophosphate 1-phosphatase activity
JJJ14_RS09405	COG1968	undecaprenyl-diphosphatase activity
JJJ14_RS09430	COG0420	3'-5' exonuclease activity
JJJ14_RS09435	COG0419	ATPase involved in DNA repair
JJJ14_RS09465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JJJ14_RS09470	COG0085	RNA polymerase activity
JJJ14_RS09480	COG0222	ribosome binding
JJJ14_RS09485	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JJJ14_RS09525	COG0653	protein targeting
JJJ14_RS09535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JJJ14_RS09540	COG5401	PFAM Sporulation and spore germination
JJJ14_RS09545	COG5002	protein histidine kinase activity
JJJ14_RS09545	COG5000	phosphorelay sensor kinase activity
JJJ14_RS09550	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS09570	COG0714	Associated with various cellular activities
JJJ14_RS09575	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JJJ14_RS09590	COG2835	tetraacyldisaccharide 4'-kinase activity
JJJ14_RS09625	COG1482	cell wall glycoprotein biosynthetic process
JJJ14_RS09650	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS09655	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS09665	COG1215	transferase activity, transferring glycosyl groups
JJJ14_RS09710	COG0463	Glycosyl transferase, family 2
JJJ14_RS09725	COG1088	dTDP-glucose 4,6-dehydratase activity
JJJ14_RS09745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JJJ14_RS09760	COG0297	glycogen (starch) synthase activity
JJJ14_RS09775	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS09795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JJJ14_RS09800	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS09825	COG1316	TRANSCRIPTIONal
JJJ14_RS09830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JJJ14_RS09860	COG5002	protein histidine kinase activity
JJJ14_RS09865	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS09880	COG0424	maF-like protein
JJJ14_RS09895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JJJ14_RS09915	COG1666	GTP binding
JJJ14_RS09920	COG2197	response regulator
JJJ14_RS09940	COG0501	Belongs to the peptidase M48B family
JJJ14_RS09970	COG1137	ATPase activity
JJJ14_RS09975	COG1994	Peptidase M50
JJJ14_RS10005	COG0142	geranyltranstransferase activity
JJJ14_RS10020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JJJ14_RS10025	COG0713	ATP synthesis coupled electron transport
JJJ14_RS10040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JJJ14_RS10045	COG1034	ATP synthesis coupled electron transport
JJJ14_RS10050	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JJJ14_RS10060	COG0649	NAD binding
JJJ14_RS10065	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JJJ14_RS10070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JJJ14_RS10080	COG0644	oxidoreductase
JJJ14_RS10085	COG2226	methyltransferase
JJJ14_RS10090	COG1169	isochorismate synthase
JJJ14_RS10095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JJJ14_RS10100	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JJJ14_RS10105	COG4948	Mandelate Racemase Muconate Lactonizing
JJJ14_RS10130	COG2826	transposase and inactivated derivatives, IS30 family
JJJ14_RS10140	COG4176	ABC-type proline glycine betaine transport system permease component
JJJ14_RS10150	COG1940	carbohydrate kinase activity
JJJ14_RS10155	COG5426	von Willebrand factor, type A
JJJ14_RS10165	COG1175	transmembrane transport
JJJ14_RS10170	COG0395	ABC-type sugar transport system, permease component
JJJ14_RS10175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JJJ14_RS10185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JJJ14_RS10190	COG2235	arginine
JJJ14_RS10205	COG2197	response regulator
JJJ14_RS10210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JJJ14_RS10235	COG3477	response to acidic pH
JJJ14_RS10250	COG1397	ADP-ribosylglycohydrolase
JJJ14_RS10255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JJJ14_RS10275	COG0406	alpha-ribazole phosphatase activity
JJJ14_RS10280	COG2171	N-acyltransferase activity
JJJ14_RS10290	COG1053	succinate dehydrogenase
JJJ14_RS10310	COG2814	Major facilitator Superfamily
JJJ14_RS10355	COG1217	gtp-binding protein TYPA
JJJ14_RS10395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JJJ14_RS10400	COG0601	transmembrane transport
JJJ14_RS10410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JJJ14_RS10420	COG2267	carboxylic ester hydrolase activity
JJJ14_RS10435	COG1902	pentaerythritol trinitrate reductase activity
JJJ14_RS10440	COG3012	SEC-C Motif Domain Protein
JJJ14_RS10445	COG1362	aminopeptidase activity
JJJ14_RS10450	COG0546	phosphoglycolate phosphatase activity
JJJ14_RS10555	COG0698	ribose 5-phosphate isomerase
JJJ14_RS10560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJJ14_RS10565	COG0596	Alpha beta hydrolase
JJJ14_RS10565	COG0508	dehydrogenase complex catalyzes the overall conversion of
JJJ14_RS10575	COG2197	response regulator
JJJ14_RS10580	COG3851	Histidine kinase
JJJ14_RS10595	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JJJ14_RS10605	COG0574	Belongs to the PEP-utilizing enzyme family
JJJ14_RS10605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JJJ14_RS10615	COG2211	Major facilitator Superfamily
JJJ14_RS10625	COG0297	glycogen (starch) synthase activity
JJJ14_RS10625	COG0438	transferase activity, transferring glycosyl groups
JJJ14_RS10660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JJJ14_RS10675	COG1490	D-aminoacyl-tRNA deacylase activity
JJJ14_RS10685	COG0354	folic acid binding
JJJ14_RS10690	COG3485	protocatechuate 3,4-dioxygenase
JJJ14_RS10700	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS10705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JJJ14_RS10725	COG0494	nUDIX hydrolase
JJJ14_RS10725	COG0406	alpha-ribazole phosphatase activity
JJJ14_RS10730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JJJ14_RS10755	COG0513	Belongs to the DEAD box helicase family
JJJ14_RS10760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JJJ14_RS10770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JJJ14_RS10775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJJ14_RS10810	COG0431	NADPH-dependent FMN reductase
JJJ14_RS10815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JJJ14_RS10825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JJJ14_RS10840	COG0444	Belongs to the ABC transporter superfamily
JJJ14_RS10880	COG2197	response regulator
JJJ14_RS10885	COG0193	aminoacyl-tRNA hydrolase activity
JJJ14_RS10890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JJJ14_RS10925	COG0148	phosphopyruvate hydratase activity
JJJ14_RS10965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JJJ14_RS10980	COG1309	transcriptional regulator
JJJ14_RS11065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JJJ14_RS11070	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JJJ14_RS11070	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JJJ14_RS11080	COG0714	Associated with various cellular activities
JJJ14_RS11120	COG0488	(ABC) transporter
JJJ14_RS11125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JJJ14_RS11130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JJJ14_RS11145	COG0084	hydrolase, TatD family'
JJJ14_RS11150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JJJ14_RS11160	COG1335	isochorismatase
JJJ14_RS11185	COG0583	DNA-binding transcription factor activity
JJJ14_RS11210	COG1297	OPT oligopeptide transporter protein
JJJ14_RS11215	COG1215	transferase activity, transferring glycosyl groups
JJJ14_RS11260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JJJ14_RS11270	COG1970	mechanosensitive ion channel activity
JJJ14_RS11300	COG1388	LysM domain
JJJ14_RS11300	COG0791	NLP P60 protein
JJJ14_RS11300	COG3103	Sh3 type 3 domain protein
JJJ14_RS11325	COG2252	PERMEase
JJJ14_RS11330	COG1201	RNA secondary structure unwinding
JJJ14_RS11355	COG1061	Type III restriction enzyme res subunit
JJJ14_RS11370	COG1842	Phage shock protein A
JJJ14_RS11380	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS11385	COG2205	protein histidine kinase activity
JJJ14_RS11400	COG0459	protein refolding
JJJ14_RS11415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JJJ14_RS11430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JJJ14_RS11435	COG0215	cysteine-tRNA ligase activity
JJJ14_RS11440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JJJ14_RS11475	COG3842	ATPase activity
JJJ14_RS11505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JJJ14_RS11525	COG0561	phosphatase activity
JJJ14_RS11545	COG3716	PTS system mannose fructose sorbose family IID component
JJJ14_RS11550	COG3715	PTS system
JJJ14_RS11555	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JJJ14_RS11555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ14_RS11560	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JJJ14_RS11575	COG1621	beta-fructofuranosidase activity
JJJ14_RS11580	COG1609	Transcriptional regulator
JJJ14_RS11585	COG0546	phosphoglycolate phosphatase activity
JJJ14_RS11610	COG0542	response to heat
JJJ14_RS11630	COG2826	transposase and inactivated derivatives, IS30 family
JJJ14_RS11640	COG0577	efflux transmembrane transporter activity
JJJ14_RS11640	COG1136	(ABC) transporter
JJJ14_RS11660	COG0745	RESPONSE REGULATOR receiver
JJJ14_RS11665	COG2205	protein histidine kinase activity
JJJ14_RS11685	COG2311	Membrane
JJJ14_RS11690	COG0789	Transcriptional regulator
JJJ14_RS11695	COG0484	heat shock protein binding
JJJ14_RS11700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JJJ14_RS11705	COG0443	Heat shock 70 kDa protein
JJJ14_RS11725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JJJ14_RS11730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ14_RS11755	COG2197	response regulator
JJJ14_RS11760	COG4585	Histidine kinase
JJJ14_RS11800	COG0778	Nitroreductase
JJJ14_RS11835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JJJ14_RS11885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JJJ14_RS11955	COG3842	ATPase activity
JJJ14_RS11995	COG0247	lactate metabolic process
JJJ14_RS11995	COG2181	nitrate reductase activity
JJJ14_RS12000	COG2826	transposase and inactivated derivatives, IS30 family
JJJ14_RS12015	COG1131	(ABC) transporter
JJJ14_RS12025	COG2197	response regulator
JJJ14_RS12030	COG2197	response regulator
JJJ14_RS12065	COG0842	Transport permease protein
JJJ14_RS12100	COG2197	response regulator
JJJ14_RS12110	COG2801	Transposase and inactivated derivatives
JJJ14_RS12110	COG3415	Transposase
JJJ14_RS12135	COG0515	serine threonine protein kinase
JJJ14_RS12150	COG1131	(ABC) transporter
JJJ14_RS12175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JJJ14_RS12190	COG3851	Histidine kinase
JJJ14_RS12195	COG2197	response regulator
JJJ14_RS12205	COG2755	lipolytic protein G-D-S-L family
JJJ14_RS12220	COG0483	inositol monophosphate 1-phosphatase activity
JJJ14_RS12225	COG1113	amino acid transport
JJJ14_RS12235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JJJ14_RS12240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JJJ14_RS12245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JJJ14_RS12245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JJJ14_RS12250	COG1940	carbohydrate kinase activity
JJJ14_RS12255	COG0628	permease
JJJ14_RS12265	COG1854	S-ribosylhomocysteine lyase activity
JJJ14_RS12275	COG2409	Drug exporters of the RND superfamily
JJJ14_RS12295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JJJ14_RS12315	COG2985	domain, Protein
JJJ14_RS12315	COG0569	domain protein
JJJ14_RS12320	COG1966	Carbon starvation protein
JJJ14_RS12340	COG1716	ATPase activity
JJJ14_RS12345	COG1716	ATPase activity
JJJ14_RS12360	COG0768	penicillin binding
JJJ14_RS12365	COG0515	serine threonine protein kinase
JJJ14_RS12370	COG2815	serine threonine protein kinase
JJJ14_RS12370	COG0515	serine threonine protein kinase
JJJ14_RS12375	COG2197	response regulator
JJJ14_RS12395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JJJ14_RS12400	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JJJ14_RS12440	COG3345	alpha-galactosidase
JJJ14_RS12445	COG0673	inositol 2-dehydrogenase activity
JJJ14_RS12450	COG0617	tRNA 3'-terminal CCA addition
JJJ14_RS12465	COG0728	peptidoglycan biosynthetic process
JJJ14_RS12470	COG0492	ferredoxin-NADP+ reductase activity
JJJ14_RS12475	COG3118	belongs to the thioredoxin family
JJJ14_RS12485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JJJ14_RS12490	COG1181	Belongs to the D-alanine--D-alanine ligase family
JJJ14_RS12505	COG0357	Ribosomal RNA small subunit methyltransferase G
JJJ14_RS12515	COG0706	membrane insertase activity
JJJ14_RS12520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JJJ14_RS12525	COG0594	ribonuclease P activity
JJJ14_RS12530	COG0230	Belongs to the bacterial ribosomal protein bL34 family