locus-tag	class	description
JJJ15_RS00005	COG0358	DNA primase activity
JJJ15_RS00010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JJJ15_RS00040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JJJ15_RS00070	COG1420	regulation of RNA biosynthetic process
JJJ15_RS00075	COG0484	heat shock protein binding
JJJ15_RS00130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JJJ15_RS00140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JJJ15_RS00150	COG0477	Major facilitator Superfamily
JJJ15_RS00150	COG2814	Major facilitator Superfamily
JJJ15_RS00155	COG1476	TRANSCRIPTIONal
JJJ15_RS00165	COG1131	(ABC) transporter
JJJ15_RS00170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JJJ15_RS00175	COG1381	Involved in DNA repair and RecF pathway recombination
JJJ15_RS00180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JJJ15_RS00190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JJJ15_RS00195	COG1116	anion transmembrane transporter activity
JJJ15_RS00205	COG0423	glycine-tRNA ligase activity
JJJ15_RS00215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JJJ15_RS00230	COG0560	Phosphoserine phosphatase
JJJ15_RS00240	COG0297	glycogen (starch) synthase activity
JJJ15_RS00250	COG1119	ATPase activity
JJJ15_RS00285	COG0488	(ABC) transporter
JJJ15_RS00320	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JJJ15_RS00325	COG2815	serine threonine protein kinase
JJJ15_RS00325	COG0515	serine threonine protein kinase
JJJ15_RS00330	COG0142	geranyltranstransferase activity
JJJ15_RS00335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JJJ15_RS00340	COG1160	GTP binding
JJJ15_RS00355	COG0166	Belongs to the GPI family
JJJ15_RS00380	COG0561	phosphatase activity
JJJ15_RS00400	COG0363	glucosamine-6-phosphate deaminase activity
JJJ15_RS00415	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JJJ15_RS00440	COG0443	Heat shock 70 kDa protein
JJJ15_RS00455	COG1621	beta-fructofuranosidase activity
JJJ15_RS00460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ15_RS00460	COG1263	PTS System
JJJ15_RS00460	COG2190	(PTS) system
JJJ15_RS00475	COG0546	phosphoglycolate phosphatase activity
JJJ15_RS00495	COG0205	6-phosphofructokinase activity
JJJ15_RS00520	COG0805	protein transport
JJJ15_RS00525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JJJ15_RS00530	COG2378	regulation of single-species biofilm formation
JJJ15_RS00545	COG0140	phosphoribosyl-ATP diphosphatase activity
JJJ15_RS00550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JJJ15_RS00560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JJJ15_RS00565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JJJ15_RS00570	COG1881	PFAM PEBP family protein
JJJ15_RS00580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JJJ15_RS00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJJ15_RS00595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JJJ15_RS00600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JJJ15_RS00605	COG0531	amino acid
JJJ15_RS00610	COG0569	domain protein
JJJ15_RS00655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JJJ15_RS00665	COG0187	DNA topoisomerase II activity
JJJ15_RS00695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JJJ15_RS00715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JJJ15_RS00720	COG0149	triose-phosphate isomerase activity
JJJ15_RS00730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JJJ15_RS00735	COG1481	regulation of sporulation
JJJ15_RS00745	COG1660	Displays ATPase and GTPase activities
JJJ15_RS00770	COG0322	excinuclease ABC activity
JJJ15_RS00775	COG0561	phosphatase activity
JJJ15_RS00800	COG0483	inositol monophosphate 1-phosphatase activity
JJJ15_RS00840	COG1929	Belongs to the glycerate kinase type-1 family
JJJ15_RS00845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JJJ15_RS00855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JJJ15_RS00860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JJJ15_RS00865	COG4770	biotin carboxylase activity
JJJ15_RS00885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JJJ15_RS00895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JJJ15_RS00905	COG1470	cell adhesion involved in biofilm formation
JJJ15_RS00905	COG0366	Alpha amylase catalytic
JJJ15_RS00915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JJJ15_RS00925	COG1758	RNA polymerase activity
JJJ15_RS00930	COG0194	GDP metabolic process
JJJ15_RS00935	COG0194	GDP metabolic process
JJJ15_RS00940	COG0284	orotidine-5'-phosphate decarboxylase activity
JJJ15_RS00945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JJJ15_RS00950	COG0505	Belongs to the CarA family
JJJ15_RS00955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JJJ15_RS00960	COG0540	Belongs to the ATCase OTCase family
JJJ15_RS00965	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JJJ15_RS00975	COG0702	epimerase
JJJ15_RS00980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JJJ15_RS00985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JJJ15_RS01000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JJJ15_RS01005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JJJ15_RS01010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JJJ15_RS01020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JJJ15_RS01030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JJJ15_RS01040	COG2409	Drug exporters of the RND superfamily
JJJ15_RS01045	COG0009	L-threonylcarbamoyladenylate synthase
JJJ15_RS01060	COG0640	Transcriptional regulator
JJJ15_RS01070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JJJ15_RS01100	COG4651	solute:proton antiporter activity
JJJ15_RS01100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JJJ15_RS01105	COG0124	histidyl-tRNA synthetase
JJJ15_RS01110	COG0556	nucleotide-excision repair
JJJ15_RS01130	COG0237	dephospho-CoA kinase activity
JJJ15_RS01145	COG0539	negative regulation of cytoplasmic translation
JJJ15_RS01155	COG2050	protein possibly involved in aromatic compounds catabolism
JJJ15_RS01175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JJJ15_RS01180	COG0134	indole-3-glycerol-phosphate synthase activity
JJJ15_RS01195	COG0107	imidazoleglycerol-phosphate synthase activity
JJJ15_RS01205	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JJJ15_RS01215	COG4122	O-methyltransferase activity
JJJ15_RS01220	COG1222	aaa ATPase
JJJ15_RS01240	COG1994	Peptidase M50
JJJ15_RS01240	COG0517	IMP dehydrogenase activity
JJJ15_RS01250	COG0656	L-ascorbic acid biosynthetic process
JJJ15_RS01260	COG1252	NADH dehydrogenase
JJJ15_RS01275	COG0477	Major facilitator Superfamily
JJJ15_RS01285	COG0628	permease
JJJ15_RS01295	COG0676	glucose-6-phosphate 1-epimerase activity
JJJ15_RS01300	COG0546	phosphoglycolate phosphatase activity
JJJ15_RS01310	COG0671	phosphoesterase, PA-phosphatase related
JJJ15_RS01360	COG1882	Formate acetyltransferase
JJJ15_RS01375	COG0038	chloride channel
JJJ15_RS01385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JJJ15_RS01390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJJ15_RS01395	COG0508	dehydrogenase complex catalyzes the overall conversion of
JJJ15_RS01405	COG0321	lipoyl(octanoyl) transferase activity
JJJ15_RS01410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JJJ15_RS01450	COG0765	amino acid transport
JJJ15_RS01455	COG1126	abc transporter atp-binding protein
JJJ15_RS01465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JJJ15_RS01470	COG0174	glutamine synthetase
JJJ15_RS01485	COG0488	(ABC) transporter
JJJ15_RS01500	COG1196	nuclear chromosome segregation
JJJ15_RS01510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JJJ15_RS01515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JJJ15_RS01520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JJJ15_RS01525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JJJ15_RS01535	COG2255	four-way junction helicase activity
JJJ15_RS01540	COG0632	four-way junction helicase activity
JJJ15_RS01545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JJJ15_RS01550	COG0217	transcriptional regulatory protein
JJJ15_RS01555	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JJJ15_RS01560	COG0494	nUDIX hydrolase
JJJ15_RS01565	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JJJ15_RS01585	COG0438	transferase activity, transferring glycosyl groups
JJJ15_RS01590	COG1560	Kdo2-lipid A biosynthetic process
JJJ15_RS01595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JJJ15_RS01605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JJJ15_RS01610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JJJ15_RS01635	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JJJ15_RS01640	COG0481	GTPase activity
JJJ15_RS01650	COG0133	tryptophan synthase activity
JJJ15_RS01670	COG0512	Glutamine amidotransferase of anthranilate synthase
JJJ15_RS01675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JJJ15_RS01685	COG0159	tryptophan synthase activity
JJJ15_RS01705	COG1122	ATPase activity
JJJ15_RS01710	COG0268	Binds directly to 16S ribosomal RNA
JJJ15_RS01715	COG4868	Belongs to the UPF0371 family
JJJ15_RS01730	COG2183	response to ionizing radiation
JJJ15_RS01735	COG1307	EDD domain protein, DegV family
JJJ15_RS01740	COG0495	leucyl-tRNA aminoacylation
JJJ15_RS01745	COG0537	adenosine 5'-monophosphoramidase activity
JJJ15_RS01775	COG0733	neurotransmitter:sodium symporter activity
JJJ15_RS01780	COG0813	purine-nucleoside phosphorylase activity
JJJ15_RS01830	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JJJ15_RS01835	COG1027	Aspartate ammonia-lyase
JJJ15_RS01845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JJJ15_RS01860	COG3552	Protein containing von Willebrand factor type A (VWA) domain
JJJ15_RS01865	COG0714	Associated with various cellular activities
JJJ15_RS02050	COG0582	viral genome integration into host DNA
JJJ15_RS02075	COG0799	negative regulation of ribosome biogenesis
JJJ15_RS02085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JJJ15_RS02090	COG1349	DNA-binding transcription factor activity
JJJ15_RS02105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JJJ15_RS02110	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JJJ15_RS02115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JJJ15_RS02120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JJJ15_RS02125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JJJ15_RS02130	COG1530	ribonuclease E activity
JJJ15_RS02135	COG1271	oxidase subunit
JJJ15_RS02140	COG1294	oxidase, subunit
JJJ15_RS02145	COG0641	radical SAM
JJJ15_RS02165	COG4988	ABC transporter
JJJ15_RS02170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JJJ15_RS02185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JJJ15_RS02190	COG0571	ribonuclease III activity
JJJ15_RS02205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JJJ15_RS02215	COG3119	arylsulfatase activity
JJJ15_RS02225	COG1609	Transcriptional regulator
JJJ15_RS02230	COG2814	Major facilitator Superfamily
JJJ15_RS02240	COG1461	Dihydroxyacetone kinase
JJJ15_RS02245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JJJ15_RS02275	COG1181	Belongs to the D-alanine--D-alanine ligase family
JJJ15_RS02285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JJJ15_RS02295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JJJ15_RS02310	COG0438	transferase activity, transferring glycosyl groups
JJJ15_RS02315	COG1132	(ABC) transporter
JJJ15_RS02330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JJJ15_RS02335	COG5002	protein histidine kinase activity
JJJ15_RS02340	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS02350	COG0066	3-isopropylmalate dehydratase activity
JJJ15_RS02390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JJJ15_RS02400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JJJ15_RS02410	COG1472	Belongs to the glycosyl hydrolase 3 family
JJJ15_RS02420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JJJ15_RS02430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JJJ15_RS02435	COG0612	Peptidase, M16
JJJ15_RS02445	COG1185	polyribonucleotide nucleotidyltransferase activity
JJJ15_RS02465	COG2814	Major facilitator Superfamily
JJJ15_RS02470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JJJ15_RS02475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JJJ15_RS02485	COG1674	ftsk spoiiie
JJJ15_RS02490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JJJ15_RS02490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JJJ15_RS02500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JJJ15_RS02530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JJJ15_RS02545	COG0179	Fumarylacetoacetate (FAA) hydrolase
JJJ15_RS02550	COG1115	amino acid carrier protein
JJJ15_RS02555	COG1115	amino acid carrier protein
JJJ15_RS02565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JJJ15_RS02585	COG0739	heme binding
JJJ15_RS02595	COG2884	Cell division ATP-binding protein ftsE
JJJ15_RS02620	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JJJ15_RS02625	COG0515	serine threonine protein kinase
JJJ15_RS02630	COG0515	serine threonine protein kinase
JJJ15_RS02635	COG1716	ATPase activity
JJJ15_RS02635	COG1131	(ABC) transporter
JJJ15_RS02635	COG0842	Transport permease protein
JJJ15_RS02645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JJJ15_RS02650	COG0473	3-isopropylmalate dehydrogenase activity
JJJ15_RS02655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JJJ15_RS02670	COG0569	domain protein
JJJ15_RS02670	COG2985	domain, Protein
JJJ15_RS02680	COG0549	Belongs to the carbamate kinase family
JJJ15_RS02685	COG0708	Exodeoxyribonuclease III
JJJ15_RS02715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JJJ15_RS02735	COG0315	cyclic pyranopterin monophosphate synthase activity
JJJ15_RS02740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JJJ15_RS02740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JJJ15_RS02745	COG0521	Mo-molybdopterin cofactor biosynthetic process
JJJ15_RS02745	COG0315	cyclic pyranopterin monophosphate synthase activity
JJJ15_RS02760	COG1140	nitrate reductase beta subunit
JJJ15_RS02790	COG1132	(ABC) transporter
JJJ15_RS02795	COG1132	(ABC) transporter
JJJ15_RS02795	COG2375	cellular response to nickel ion
JJJ15_RS02800	COG1129	ABC transporter
JJJ15_RS02815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JJJ15_RS02825	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ15_RS02830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ15_RS02840	COG1120	ATPase activity
JJJ15_RS02850	COG2249	NAD(P)H dehydrogenase (quinone) activity
JJJ15_RS02860	COG1063	alcohol dehydrogenase
JJJ15_RS02865	COG0483	inositol monophosphate 1-phosphatase activity
JJJ15_RS02870	COG1968	undecaprenyl-diphosphatase activity
JJJ15_RS02875	COG0420	3'-5' exonuclease activity
JJJ15_RS02880	COG0419	ATPase involved in DNA repair
JJJ15_RS02885	COG4750	Nucleotidyl transferase
JJJ15_RS02890	COG0697	spore germination
JJJ15_RS02935	COG0653	protein targeting
JJJ15_RS02940	COG1040	competence protein
JJJ15_RS02945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JJJ15_RS02955	COG5000	phosphorelay sensor kinase activity
JJJ15_RS02955	COG5002	protein histidine kinase activity
JJJ15_RS02960	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS02980	COG0714	Associated with various cellular activities
JJJ15_RS03000	COG1663	tetraacyldisaccharide 4'-kinase activity
JJJ15_RS03000	COG2835	tetraacyldisaccharide 4'-kinase activity
JJJ15_RS03035	COG1482	cell wall glycoprotein biosynthetic process
JJJ15_RS03045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JJJ15_RS03050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JJJ15_RS03075	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JJJ15_RS03080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JJJ15_RS03085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JJJ15_RS03090	COG0254	rRNA binding
JJJ15_RS03095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JJJ15_RS03100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JJJ15_RS03110	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JJJ15_RS03120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JJJ15_RS03125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JJJ15_RS03130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JJJ15_RS03135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JJJ15_RS03140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JJJ15_RS03145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JJJ15_RS03155	COG0356	it plays a direct role in the translocation of protons across the membrane
JJJ15_RS03180	COG2197	response regulator
JJJ15_RS03200	COG0693	protein deglycase activity
JJJ15_RS03225	COG0513	Belongs to the DEAD box helicase family
JJJ15_RS03230	COG2095	MarC family integral membrane protein
JJJ15_RS03240	COG0673	inositol 2-dehydrogenase activity
JJJ15_RS03245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JJJ15_RS03250	COG0006	proline dipeptidase activity
JJJ15_RS03270	COG0714	Associated with various cellular activities
JJJ15_RS03300	COG2239	Acts as a magnesium transporter
JJJ15_RS03310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JJJ15_RS03310	COG2755	lipolytic protein G-D-S-L family
JJJ15_RS03315	COG0489	protein tyrosine kinase activity
JJJ15_RS03315	COG2151	metal-sulfur cluster biosynthetic enzyme
JJJ15_RS03320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JJJ15_RS03330	COG0673	inositol 2-dehydrogenase activity
JJJ15_RS03340	COG1175	transmembrane transport
JJJ15_RS03345	COG0395	ABC-type sugar transport system, permease component
JJJ15_RS03355	COG0285	dihydrofolate synthase activity
JJJ15_RS03370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JJJ15_RS03380	COG0346	lactoylglutathione lyase activity
JJJ15_RS03400	COG1174	glycine betaine transport
JJJ15_RS03405	COG1125	glycine betaine transport
JJJ15_RS03405	COG0517	IMP dehydrogenase activity
JJJ15_RS03430	COG0114	fumarate hydratase activity
JJJ15_RS03435	COG2315	Protein conserved in bacteria
JJJ15_RS03450	COG1397	ADP-ribosylglycohydrolase
JJJ15_RS03495	COG1674	ftsk spoiiie
JJJ15_RS03535	COG1349	DNA-binding transcription factor activity
JJJ15_RS03540	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JJJ15_RS03550	COG1136	(ABC) transporter
JJJ15_RS03550	COG0577	efflux transmembrane transporter activity
JJJ15_RS03555	COG0577	efflux transmembrane transporter activity
JJJ15_RS03555	COG1136	(ABC) transporter
JJJ15_RS03585	COG3475	LICD family
JJJ15_RS03605	COG0463	Glycosyl transferase, family 2
JJJ15_RS03635	COG1216	Glycosyl transferase, family 2
JJJ15_RS03645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JJJ15_RS03645	COG2755	lipolytic protein G-D-S-L family
JJJ15_RS03705	COG1316	TRANSCRIPTIONal
JJJ15_RS03710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JJJ15_RS03740	COG5002	protein histidine kinase activity
JJJ15_RS03745	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS03760	COG0424	maF-like protein
JJJ15_RS03775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JJJ15_RS03795	COG1666	GTP binding
JJJ15_RS03800	COG2195	Cleaves the N-terminal amino acid of tripeptides
JJJ15_RS03805	COG0501	Belongs to the peptidase M48B family
JJJ15_RS03820	COG0686	Belongs to the AlaDH PNT family
JJJ15_RS03860	COG4974	Belongs to the 'phage' integrase family
JJJ15_RS03875	COG0792	nuclease activity
JJJ15_RS03885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JJJ15_RS03890	COG0681	Belongs to the peptidase S26 family
JJJ15_RS03910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JJJ15_RS03915	COG1837	Belongs to the UPF0109 family
JJJ15_RS03920	COG0228	four-way junction DNA binding
JJJ15_RS03930	COG1131	(ABC) transporter
JJJ15_RS03945	COG1131	(ABC) transporter
JJJ15_RS03955	COG4585	Histidine kinase
JJJ15_RS03960	COG2197	response regulator
JJJ15_RS03975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JJJ15_RS03980	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JJJ15_RS03990	COG1194	a g-specific adenine glycosylase
JJJ15_RS04000	COG2197	response regulator
JJJ15_RS04010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JJJ15_RS04015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JJJ15_RS04020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JJJ15_RS04040	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JJJ15_RS04045	COG2949	membrane
JJJ15_RS04055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JJJ15_RS04065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JJJ15_RS04070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JJJ15_RS04075	COG1053	succinate dehydrogenase
JJJ15_RS04095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JJJ15_RS04105	COG0802	atpase or kinase
JJJ15_RS04110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JJJ15_RS04115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JJJ15_RS04115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JJJ15_RS04120	COG0736	holo-[acyl-carrier-protein] synthase activity
JJJ15_RS04130	COG1072	(Pantothenic acid kinase))
JJJ15_RS04170	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JJJ15_RS04175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JJJ15_RS04180	COG0101	tRNA pseudouridine synthase activity
JJJ15_RS04190	COG1252	NADH dehydrogenase
JJJ15_RS04195	COG0203	ribosomal protein L17
JJJ15_RS04200	COG0202	RNA polymerase activity
JJJ15_RS04205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JJJ15_RS04210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JJJ15_RS04215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JJJ15_RS04220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JJJ15_RS04240	COG0563	adenylate kinase activity
JJJ15_RS04250	COG0200	Binds to the 23S rRNA
JJJ15_RS04255	COG1841	ribosomal large subunit assembly
JJJ15_RS04260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JJJ15_RS04265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JJJ15_RS04270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JJJ15_RS04280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JJJ15_RS04285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JJJ15_RS04290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JJJ15_RS04295	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JJJ15_RS04300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JJJ15_RS04305	COG0255	Belongs to the universal ribosomal protein uL29 family
JJJ15_RS04310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JJJ15_RS04315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JJJ15_RS04320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JJJ15_RS04325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JJJ15_RS04330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JJJ15_RS04335	COG0089	rRNA binding
JJJ15_RS04345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JJJ15_RS04350	COG0051	transcription antitermination factor activity, RNA binding
JJJ15_RS04370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JJJ15_RS04375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JJJ15_RS04380	COG0049	tRNA binding
JJJ15_RS04385	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JJJ15_RS04445	COG1674	ftsk spoiiie
JJJ15_RS04455	COG2815	serine threonine protein kinase
JJJ15_RS04455	COG0515	serine threonine protein kinase
JJJ15_RS04485	COG0714	Associated with various cellular activities
JJJ15_RS04590	COG4245	von Willebrand factor, type A
JJJ15_RS04615	COG2197	response regulator
JJJ15_RS04640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JJJ15_RS04675	COG1674	ftsk spoiiie
JJJ15_RS04680	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JJJ15_RS04685	COG0085	RNA polymerase activity
JJJ15_RS04690	COG0222	ribosome binding
JJJ15_RS04695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JJJ15_RS04705	COG0081	regulation of translation
JJJ15_RS04710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JJJ15_RS04715	COG0250	Participates in transcription elongation, termination and antitermination
JJJ15_RS04730	COG0436	Aminotransferase
JJJ15_RS04740	COG2226	methyltransferase
JJJ15_RS04745	COG1169	isochorismate synthase
JJJ15_RS04750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JJJ15_RS04755	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JJJ15_RS04760	COG4948	Mandelate Racemase Muconate Lactonizing
JJJ15_RS04765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JJJ15_RS04770	COG2235	arginine
JJJ15_RS04780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JJJ15_RS04785	COG3477	response to acidic pH
JJJ15_RS04810	COG0406	alpha-ribazole phosphatase activity
JJJ15_RS04815	COG2171	N-acyltransferase activity
JJJ15_RS04830	COG4115	mRNA cleavage
JJJ15_RS04855	COG1217	gtp-binding protein TYPA
JJJ15_RS04895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JJJ15_RS04900	COG0601	transmembrane transport
JJJ15_RS04905	COG4166	transmembrane transport
JJJ15_RS04910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JJJ15_RS04930	COG1902	pentaerythritol trinitrate reductase activity
JJJ15_RS04935	COG1362	aminopeptidase activity
JJJ15_RS04995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JJJ15_RS05015	COG0542	response to heat
JJJ15_RS05135	COG0247	lactate metabolic process
JJJ15_RS05135	COG2181	nitrate reductase activity
JJJ15_RS05150	COG2375	cellular response to nickel ion
JJJ15_RS05150	COG1132	(ABC) transporter
JJJ15_RS05180	COG1121	(ABC) transporter
JJJ15_RS05190	COG0803	Belongs to the bacterial solute-binding protein 9 family
JJJ15_RS05200	COG3250	beta-galactosidase activity
JJJ15_RS05215	COG1263	PTS System
JJJ15_RS05215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ15_RS05215	COG2190	(PTS) system
JJJ15_RS05220	COG0542	response to heat
JJJ15_RS05245	COG0789	Transcriptional regulator
JJJ15_RS05250	COG0484	heat shock protein binding
JJJ15_RS05255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JJJ15_RS05260	COG0443	Heat shock 70 kDa protein
JJJ15_RS05280	COG2197	response regulator
JJJ15_RS05355	COG3842	ATPase activity
JJJ15_RS05380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JJJ15_RS05390	COG0596	Alpha beta hydrolase
JJJ15_RS05420	COG1408	metallophosphoesterase
JJJ15_RS05580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JJJ15_RS05585	COG0789	Transcriptional regulator
JJJ15_RS05595	COG1131	(ABC) transporter
JJJ15_RS05645	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JJJ15_RS05665	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JJJ15_RS05675	COG1737	Transcriptional regulator
JJJ15_RS05680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JJJ15_RS05685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JJJ15_RS05690	COG1121	(ABC) transporter
JJJ15_RS05695	COG0803	Belongs to the bacterial solute-binding protein 9 family
JJJ15_RS05700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JJJ15_RS05720	COG1309	transcriptional regulator
JJJ15_RS05725	COG1131	(ABC) transporter
JJJ15_RS05765	COG2233	PERMEase
JJJ15_RS05780	COG0215	cysteine-tRNA ligase activity
JJJ15_RS05785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JJJ15_RS05815	COG1309	transcriptional regulator
JJJ15_RS05840	COG1216	Glycosyl transferase, family 2
JJJ15_RS05845	COG0488	(ABC) transporter
JJJ15_RS05850	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JJJ15_RS05855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JJJ15_RS05870	COG0084	hydrolase, TatD family'
JJJ15_RS05875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JJJ15_RS05885	COG1335	isochorismatase
JJJ15_RS05905	COG0252	asparaginase activity
JJJ15_RS05915	COG0470	DNA polymerase III
JJJ15_RS05920	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JJJ15_RS05945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JJJ15_RS05950	COG1329	Transcriptional regulator
JJJ15_RS05955	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS05960	COG5002	protein histidine kinase activity
JJJ15_RS05970	COG1216	Glycosyl transferase, family 2
JJJ15_RS06030	COG0515	serine threonine protein kinase
JJJ15_RS06050	COG0714	Associated with various cellular activities
JJJ15_RS06060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JJJ15_RS06060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JJJ15_RS06065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JJJ15_RS06145	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JJJ15_RS06150	COG0626	cystathionine gamma-synthase activity
JJJ15_RS06180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JJJ15_RS06190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JJJ15_RS06195	COG0561	phosphatase activity
JJJ15_RS06200	COG0561	phosphatase activity
JJJ15_RS06205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JJJ15_RS06205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JJJ15_RS06210	COG0584	glycerophosphoryl diester phosphodiesterase
JJJ15_RS06220	COG1404	Belongs to the peptidase S8 family
JJJ15_RS06240	COG1653	transport
JJJ15_RS06250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JJJ15_RS06270	COG1203	CRISPR-associated helicase, Cas3
JJJ15_RS06315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JJJ15_RS06325	COG1263	PTS System
JJJ15_RS06325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ15_RS06330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JJJ15_RS06335	COG1737	Transcriptional regulator
JJJ15_RS06340	COG1609	Transcriptional regulator
JJJ15_RS06350	COG2211	Major facilitator Superfamily
JJJ15_RS06365	COG3177	Filamentation induced by cAMP protein fic
JJJ15_RS06370	COG0385	Bile acid
JJJ15_RS06380	COG3311	Transcriptional regulator
JJJ15_RS06400	COG3852	Histidine kinase
JJJ15_RS06410	COG0471	metal ion transport
JJJ15_RS06445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ15_RS06450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ15_RS06455	COG1120	ATPase activity
JJJ15_RS06465	COG1854	S-ribosylhomocysteine lyase activity
JJJ15_RS06480	COG5002	protein histidine kinase activity
JJJ15_RS06485	COG2885	chlorophyll binding
JJJ15_RS06495	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JJJ15_RS06495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JJJ15_RS06495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JJJ15_RS06500	COG1461	Dihydroxyacetone kinase
JJJ15_RS06515	COG1309	transcriptional regulator
JJJ15_RS06590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JJJ15_RS06595	COG1780	Probably involved in ribonucleotide reductase function
JJJ15_RS06605	COG1827	regulation of RNA biosynthetic process
JJJ15_RS06655	COG2197	response regulator
JJJ15_RS06710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JJJ15_RS06745	COG0395	ABC-type sugar transport system, permease component
JJJ15_RS06750	COG1175	transmembrane transport
JJJ15_RS06755	COG1653	transport
JJJ15_RS06790	COG1950	PFAM Membrane protein of
JJJ15_RS06800	COG1937	Protein conserved in bacteria
JJJ15_RS06830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JJJ15_RS06835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JJJ15_RS06850	COG0617	tRNA 3'-terminal CCA addition
JJJ15_RS06865	COG0728	peptidoglycan biosynthetic process
JJJ15_RS06870	COG0492	ferredoxin-NADP+ reductase activity
JJJ15_RS06895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JJJ15_RS06905	COG0604	alcohol dehydrogenase
JJJ15_RS06910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JJJ15_RS06915	COG1181	Belongs to the D-alanine--D-alanine ligase family
JJJ15_RS06930	COG0357	Ribosomal RNA small subunit methyltransferase G
JJJ15_RS06940	COG0706	membrane insertase activity
JJJ15_RS06945	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JJJ15_RS06950	COG0594	ribonuclease P activity
JJJ15_RS06955	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JJJ15_RS06960	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JJJ15_RS06965	COG0592	DNA-directed DNA polymerase activity
JJJ15_RS06970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JJJ15_RS06975	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JJJ15_RS06980	COG4555	ABC transporter
JJJ15_RS06995	COG0187	DNA topoisomerase II activity
JJJ15_RS07000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JJJ15_RS07065	COG3550	peptidyl-serine autophosphorylation
JJJ15_RS07075	COG1760	l-serine dehydratase
JJJ15_RS07080	COG0351	phosphomethylpyrimidine kinase
JJJ15_RS07090	COG1716	ATPase activity
JJJ15_RS07095	COG1716	ATPase activity
JJJ15_RS07110	COG0768	penicillin binding
JJJ15_RS07120	COG0515	serine threonine protein kinase
JJJ15_RS07125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JJJ15_RS07130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JJJ15_RS07140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JJJ15_RS07140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JJJ15_RS07145	COG1940	carbohydrate kinase activity
JJJ15_RS07200	COG3764	Sortase (surface protein transpeptidase)
JJJ15_RS07210	COG0156	8-amino-7-oxononanoate synthase activity
JJJ15_RS07215	COG1063	alcohol dehydrogenase
JJJ15_RS07235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JJJ15_RS07250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JJJ15_RS07255	COG0360	Binds together with S18 to 16S ribosomal RNA
JJJ15_RS07265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JJJ15_RS07270	COG0359	binds to the 23S rRNA
JJJ15_RS07285	COG0534	Mate efflux family protein
JJJ15_RS07290	COG0305	Participates in initiation and elongation during chromosome replication
JJJ15_RS07315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JJJ15_RS07360	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
JJJ15_RS07365	COG2890	protein-(glutamine-N5) methyltransferase activity
JJJ15_RS07395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JJJ15_RS07405	COG4974	Belongs to the 'phage' integrase family
JJJ15_RS07440	COG0037	tRNA processing
JJJ15_RS07440	COG0590	tRNA wobble adenosine to inosine editing
JJJ15_RS07475	COG1136	(ABC) transporter
JJJ15_RS07480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JJJ15_RS07485	COG1643	Atp-dependent helicase
JJJ15_RS07510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JJJ15_RS07510	COG0519	Catalyzes the synthesis of GMP from XMP
JJJ15_RS07595	COG1309	transcriptional regulator
JJJ15_RS07600	COG2814	Major facilitator Superfamily
JJJ15_RS07610	COG0702	epimerase
JJJ15_RS07630	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JJJ15_RS07635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JJJ15_RS07645	COG2985	domain, Protein
JJJ15_RS07645	COG0569	domain protein
JJJ15_RS07650	COG1595	DNA-templated transcription, initiation
JJJ15_RS07670	COG1131	(ABC) transporter
JJJ15_RS07690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JJJ15_RS07710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JJJ15_RS07735	COG2089	acid synthase
JJJ15_RS07740	COG1083	cytidylyl-transferase
JJJ15_RS07755	COG1216	Glycosyl transferase, family 2
JJJ15_RS07755	COG0438	transferase activity, transferring glycosyl groups
JJJ15_RS07770	COG1132	(ABC) transporter
JJJ15_RS07790	COG1754	DNA topoisomerase type I activity
JJJ15_RS07790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JJJ15_RS07865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JJJ15_RS07885	COG2205	protein histidine kinase activity
JJJ15_RS07890	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS07905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JJJ15_RS07920	COG0459	protein refolding
JJJ15_RS07935	COG2205	protein histidine kinase activity
JJJ15_RS07940	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS07950	COG0519	Catalyzes the synthesis of GMP from XMP
JJJ15_RS07950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JJJ15_RS07965	COG1842	Phage shock protein A
JJJ15_RS07990	COG1061	Type III restriction enzyme res subunit
JJJ15_RS08005	COG2252	PERMEase
JJJ15_RS08035	COG0588	phosphoglycerate mutase activity
JJJ15_RS08040	COG0148	phosphopyruvate hydratase activity
JJJ15_RS08100	COG0489	protein tyrosine kinase activity
JJJ15_RS08110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JJJ15_RS08115	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JJJ15_RS08120	COG0193	aminoacyl-tRNA hydrolase activity
JJJ15_RS08125	COG2197	response regulator
JJJ15_RS08165	COG0129	dihydroxy-acid dehydratase activity
JJJ15_RS08190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JJJ15_RS08195	COG0431	NADPH-dependent FMN reductase
JJJ15_RS08215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJJ15_RS08220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JJJ15_RS08225	COG2326	polyphosphate kinase activity
JJJ15_RS08235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JJJ15_RS08240	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JJJ15_RS08250	COG1722	exodeoxyribonuclease VII activity
JJJ15_RS08255	COG1570	exodeoxyribonuclease VII activity
JJJ15_RS08260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JJJ15_RS08265	COG0515	serine threonine protein kinase
JJJ15_RS08380	COG1674	ftsk spoiiie
JJJ15_RS08380	COG0433	COG0433 Predicted ATPase
JJJ15_RS08470	COG4143	(ABC) transporter
JJJ15_RS08480	COG3842	ATPase activity
JJJ15_RS08495	COG0326	Molecular chaperone. Has ATPase activity
JJJ15_RS08505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JJJ15_RS08525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JJJ15_RS08530	COG1643	Atp-dependent helicase
JJJ15_RS08530	COG1643	Atp-dependent helicase
JJJ15_RS08540	COG0698	ribose 5-phosphate isomerase
JJJ15_RS08545	COG0515	serine threonine protein kinase
JJJ15_RS08575	COG0702	epimerase
JJJ15_RS08605	COG0572	uridine kinase
JJJ15_RS08625	COG1132	(ABC) transporter
JJJ15_RS08625	COG2375	cellular response to nickel ion
JJJ15_RS08630	COG1132	(ABC) transporter
JJJ15_RS08655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JJJ15_RS08660	COG2860	membrane
JJJ15_RS08685	COG5650	phosphatidylinositol metabolic process
JJJ15_RS08700	COG0714	Associated with various cellular activities
JJJ15_RS08735	COG0494	nUDIX hydrolase
JJJ15_RS08765	COG2176	DNA-directed DNA polymerase activity
JJJ15_RS08780	COG0778	Nitroreductase
JJJ15_RS08805	COG0395	ABC-type sugar transport system, permease component
JJJ15_RS08815	COG0300	oxidoreductase activity
JJJ15_RS08825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JJJ15_RS08840	COG0191	fructose-bisphosphate aldolase activity
JJJ15_RS08930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JJJ15_RS08950	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JJJ15_RS08960	COG0151	Belongs to the GarS family
JJJ15_RS08975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JJJ15_RS09005	COG0047	phosphoribosylformylglycinamidine synthase activity
JJJ15_RS09020	COG0438	transferase activity, transferring glycosyl groups
JJJ15_RS09035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JJJ15_RS09050	COG2814	Major facilitator Superfamily
JJJ15_RS09095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JJJ15_RS09100	COG1349	DNA-binding transcription factor activity
JJJ15_RS09110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JJJ15_RS09110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JJJ15_RS09110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JJJ15_RS09130	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JJJ15_RS09180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJJ15_RS09200	COG0513	Belongs to the DEAD box helicase family
JJJ15_RS09265	COG1136	(ABC) transporter
JJJ15_RS09275	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JJJ15_RS09290	COG2873	o-acetylhomoserine
JJJ15_RS09295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JJJ15_RS09305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JJJ15_RS09395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JJJ15_RS09400	COG0302	gtp cyclohydrolase
JJJ15_RS09450	COG2197	response regulator
JJJ15_RS09455	COG1136	(ABC) transporter
JJJ15_RS09455	COG0577	efflux transmembrane transporter activity
JJJ15_RS09460	COG1136	(ABC) transporter
JJJ15_RS09460	COG0577	efflux transmembrane transporter activity
JJJ15_RS09465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JJJ15_RS09470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JJJ15_RS09495	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JJJ15_RS09500	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JJJ15_RS09530	COG3104	oligopeptide transport
JJJ15_RS09540	COG1556	Lactate utilization protein
JJJ15_RS09545	COG1139	Iron-sulfur cluster binding protein
JJJ15_RS09550	COG0247	lactate metabolic process
JJJ15_RS09555	COG2205	protein histidine kinase activity
JJJ15_RS09560	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS09575	COG1136	(ABC) transporter
JJJ15_RS09580	COG0577	efflux transmembrane transporter activity
JJJ15_RS09585	COG1620	l-lactate permease
JJJ15_RS09590	COG2095	MarC family integral membrane protein
JJJ15_RS09595	COG2095	MarC family integral membrane protein
JJJ15_RS09600	COG0644	oxidoreductase
JJJ15_RS09610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JJJ15_RS09615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JJJ15_RS09620	COG0649	NAD binding
JJJ15_RS09630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JJJ15_RS09635	COG1034	ATP synthesis coupled electron transport
JJJ15_RS09640	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JJJ15_RS09645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JJJ15_RS09655	COG0713	ATP synthesis coupled electron transport
JJJ15_RS09660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JJJ15_RS09670	COG1007	ATP synthesis coupled electron transport
JJJ15_RS09675	COG0142	geranyltranstransferase activity
JJJ15_RS09680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JJJ15_RS09685	COG1518	maintenance of DNA repeat elements
JJJ15_RS09700	COG1857	crispr-associated protein
JJJ15_RS09740	COG3480	Lon protease (S16) C-terminal proteolytic domain
JJJ15_RS09760	COG1611	Belongs to the LOG family
JJJ15_RS09765	COG1615	UPF0182 protein
JJJ15_RS09770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JJJ15_RS09775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JJJ15_RS09780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JJJ15_RS09780	COG1321	iron dependent repressor
JJJ15_RS09790	COG1121	(ABC) transporter
JJJ15_RS09795	COG0803	Belongs to the bacterial solute-binding protein 9 family
JJJ15_RS09800	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JJJ15_RS09810	COG4221	oxidoreductase activity
JJJ15_RS09835	COG1136	(ABC) transporter
JJJ15_RS09840	COG0577	efflux transmembrane transporter activity
JJJ15_RS09865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JJJ15_RS09880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JJJ15_RS09890	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JJJ15_RS09895	COG0494	nUDIX hydrolase
JJJ15_RS09895	COG0406	alpha-ribazole phosphatase activity
JJJ15_RS09915	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS09930	COG4152	abc transporter atp-binding protein
JJJ15_RS09940	COG1196	nuclear chromosome segregation
JJJ15_RS09970	COG2197	response regulator
JJJ15_RS09975	COG4585	Histidine kinase
JJJ15_RS09980	COG0842	Transport permease protein
JJJ15_RS09985	COG1131	(ABC) transporter
JJJ15_RS09995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JJJ15_RS10005	COG0366	Alpha amylase catalytic
JJJ15_RS10015	COG1132	(ABC) transporter
JJJ15_RS10045	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JJJ15_RS10050	COG0714	Associated with various cellular activities
JJJ15_RS10065	COG3552	Protein containing von Willebrand factor type A (VWA) domain
JJJ15_RS10085	COG3831	ATPase activity
JJJ15_RS10090	COG3831	ATPase activity
JJJ15_RS10100	COG0482	sulfurtransferase activity
JJJ15_RS10110	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JJJ15_RS10130	COG1674	ftsk spoiiie
JJJ15_RS10140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JJJ15_RS10170	COG1490	D-aminoacyl-tRNA deacylase activity
JJJ15_RS10185	COG1695	Transcriptional regulator
JJJ15_RS10195	COG0542	response to heat
JJJ15_RS10225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JJJ15_RS10235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JJJ15_RS10235	COG0574	Belongs to the PEP-utilizing enzyme family
JJJ15_RS10245	COG0714	Associated with various cellular activities
JJJ15_RS10305	COG1674	ftsk spoiiie
JJJ15_RS10355	COG0328	RNA-DNA hybrid ribonuclease activity
JJJ15_RS10360	COG2197	response regulator
JJJ15_RS10365	COG4585	Histidine kinase
JJJ15_RS10405	COG1609	Transcriptional regulator
JJJ15_RS10410	COG2814	Major facilitator Superfamily
JJJ15_RS10415	COG0519	Catalyzes the synthesis of GMP from XMP
JJJ15_RS10415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JJJ15_RS10450	COG1131	(ABC) transporter
JJJ15_RS10455	COG4585	Histidine kinase
JJJ15_RS10460	COG2197	response regulator
JJJ15_RS10470	COG0667	Aldo Keto reductase
JJJ15_RS10485	COG0656	L-ascorbic acid biosynthetic process
JJJ15_RS10490	COG3620	sequence-specific DNA binding
JJJ15_RS10495	COG2814	Major facilitator Superfamily
JJJ15_RS10505	COG3541	Predicted nucleotidyltransferase
JJJ15_RS10530	COG0789	Transcriptional regulator
JJJ15_RS10530	COG4978	Transcriptional regulator
JJJ15_RS10585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JJJ15_RS10615	COG2205	protein histidine kinase activity
JJJ15_RS10620	COG0745	RESPONSE REGULATOR receiver
JJJ15_RS10635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JJJ15_RS10640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ15_RS10650	COG2190	(PTS) system
JJJ15_RS10655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ15_RS10660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ15_RS10665	COG2188	Transcriptional regulator
JJJ15_RS10670	COG1263	PTS System
JJJ15_RS10695	COG1131	(ABC) transporter
JJJ15_RS10705	COG3590	peptidase
JJJ15_RS10730	COG1045	serine acetyltransferase
JJJ15_RS10740	COG1739	Uncharacterized protein family UPF0029
JJJ15_RS10765	COG0544	peptidyl-prolyl cis-trans isomerase activity
JJJ15_RS10785	COG1116	anion transmembrane transporter activity
JJJ15_RS10790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JJJ15_RS10800	COG0740	serine-type endopeptidase activity
JJJ15_RS10805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JJJ15_RS10810	COG0287	Prephenate dehydrogenase
JJJ15_RS10810	COG1605	Chorismate mutase
JJJ15_RS10845	COG1129	ABC transporter
JJJ15_RS10855	COG1122	ATPase activity
JJJ15_RS10860	COG2375	cellular response to nickel ion
JJJ15_RS10860	COG1132	(ABC) transporter
JJJ15_RS10870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JJJ15_RS10875	COG0366	Alpha amylase catalytic
JJJ15_RS10880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJJ15_RS10880	COG1263	PTS System
JJJ15_RS10880	COG2190	(PTS) system
JJJ15_RS10885	COG2188	Transcriptional regulator
JJJ15_RS10900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JJJ15_RS10905	COG0154	amidase activity
JJJ15_RS10910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JJJ15_RS10920	COG0052	Belongs to the universal ribosomal protein uS2 family
JJJ15_RS10925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JJJ15_RS10945	COG0233	cytoplasmic translational termination
JJJ15_RS10955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JJJ15_RS10965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JJJ15_RS10970	COG0750	zinc metalloprotease
JJJ15_RS10985	COG2233	PERMEase
JJJ15_RS10995	COG0657	acetylesterase activity
JJJ15_RS11000	COG2188	Transcriptional regulator
JJJ15_RS11005	COG0747	negative chemotaxis
JJJ15_RS11015	COG0444	Belongs to the ABC transporter superfamily
JJJ15_RS11020	COG4608	Belongs to the ABC transporter superfamily
JJJ15_RS11025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JJJ15_RS11030	COG1940	carbohydrate kinase activity
JJJ15_RS11035	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JJJ15_RS11055	COG0363	glucosamine-6-phosphate deaminase activity
JJJ15_RS11070	COG0596	Alpha beta hydrolase
JJJ15_RS11070	COG0508	dehydrogenase complex catalyzes the overall conversion of
JJJ15_RS11080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JJJ15_RS11110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JJJ15_RS11115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JJJ15_RS11165	COG3304	Inner membrane component domain
JJJ15_RS11170	COG0456	acetyltransferase
JJJ15_RS11180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JJJ15_RS11185	COG2838	Isocitrate dehydrogenase
JJJ15_RS11195	COG2304	oxidoreductase activity
JJJ15_RS11205	COG1595	DNA-templated transcription, initiation
JJJ15_RS11230	COG0508	dehydrogenase complex catalyzes the overall conversion of
JJJ15_RS11230	COG0567	Dehydrogenase, E1 component
JJJ15_RS11260	COG4604	ABC transporter, ATP-binding protein
JJJ15_RS11265	COG4605	iron ion homeostasis
JJJ15_RS11270	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJJ15_RS11275	COG4607	ABC-type enterochelin transport system periplasmic component
JJJ15_RS11285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JJJ15_RS11305	COG0018	arginyl-trna synthetase
JJJ15_RS11310	COG0019	diaminopimelate decarboxylase activity
JJJ15_RS11330	COG0460	homoserine dehydrogenase
JJJ15_RS11335	COG0083	homoserine kinase activity
JJJ15_RS11350	COG0254	rRNA binding
JJJ15_RS11355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JJJ15_RS11360	COG2890	protein-(glutamine-N5) methyltransferase activity
JJJ15_RS11365	COG2161	toxin-antitoxin pair type II binding
JJJ15_RS11370	COG4115	mRNA cleavage
JJJ15_RS11430	COG1595	DNA-templated transcription, initiation
JJJ15_RS11455	COG1175	transmembrane transport
JJJ15_RS11465	COG0366	Alpha amylase catalytic
JJJ15_RS11475	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JJJ15_RS11490	COG0205	6-phosphofructokinase activity
JJJ15_RS11615	COG0045	succinate-CoA ligase (ADP-forming) activity
JJJ15_RS11650	COG0596	Alpha beta hydrolase
JJJ15_RS11660	COG1132	(ABC) transporter
JJJ15_RS11665	COG1132	(ABC) transporter
JJJ15_RS11670	COG0039	L-malate dehydrogenase activity
JJJ15_RS11680	COG1725	Transcriptional regulator
JJJ15_RS11705	COG0058	SHG alpha-glucan phosphorylase activity
JJJ15_RS11715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JJJ15_RS11770	COG2197	response regulator
JJJ15_RS11780	COG1131	(ABC) transporter
JJJ15_RS11810	COG0442	prolyl-tRNA aminoacylation
JJJ15_RS11825	COG0779	Required for maturation of 30S ribosomal subunits
JJJ15_RS11840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JJJ15_RS11840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JJJ15_RS11855	COG1058	Belongs to the CinA family
JJJ15_RS11855	COG1546	Belongs to the CinA family
JJJ15_RS11860	COG1396	sequence-specific DNA binding
JJJ15_RS11870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JJJ15_RS11885	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JJJ15_RS11895	COG1136	(ABC) transporter
JJJ15_RS11895	COG0577	efflux transmembrane transporter activity
JJJ15_RS11910	COG2249	NAD(P)H dehydrogenase (quinone) activity
JJJ15_RS11915	COG0509	glycine decarboxylation via glycine cleavage system
JJJ15_RS11920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JJJ15_RS11925	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JJJ15_RS11925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JJJ15_RS11950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JJJ15_RS11955	COG1335	isochorismatase
JJJ15_RS11975	COG0672	)-iron permease
JJJ15_RS11995	COG0577	efflux transmembrane transporter activity
JJJ15_RS12020	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JJJ15_RS12025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JJJ15_RS12030	COG1114	Component of the transport system for branched-chain amino acids
JJJ15_RS12035	COG0477	Major facilitator Superfamily
JJJ15_RS12045	COG2813	Specifically methylates the guanine in position
JJJ15_RS12080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JJJ15_RS12090	COG0318	PFAM AMP-dependent synthetase and ligase
JJJ15_RS12095	COG0318	PFAM AMP-dependent synthetase and ligase
JJJ15_RS12115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JJJ15_RS12120	COG1285	pathogenesis
JJJ15_RS12130	COG2001	Belongs to the MraZ family
JJJ15_RS12135	COG0275	rRNA processing
JJJ15_RS12145	COG0768	penicillin binding
JJJ15_RS12150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JJJ15_RS12155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JJJ15_RS12160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JJJ15_RS12165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JJJ15_RS12180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JJJ15_RS12195	COG1496	oxidoreductase activity
JJJ15_RS12200	COG1799	cell septum assembly
JJJ15_RS12210	COG3599	regulation of cell shape
JJJ15_RS12215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JJJ15_RS12225	COG2153	protein acetylation
JJJ15_RS12230	COG0587	DNA-directed DNA polymerase activity
JJJ15_RS12235	COG2501	S4 domain
JJJ15_RS12280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JJJ15_RS12320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JJJ15_RS12345	COG0758	DNA mediated transformation
JJJ15_RS12345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JJJ15_RS12360	COG0025	NhaP-type Na H and K H
JJJ15_RS12370	COG2078	PFAM AMMECR1 domain protein
JJJ15_RS12375	COG1355	regulation of microtubule-based process
JJJ15_RS12385	COG0131	Imidazoleglycerol-phosphate dehydratase
JJJ15_RS12400	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JJJ15_RS12405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JJJ15_RS12420	COG3845	ABC transporter
JJJ15_RS12430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JJJ15_RS12435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JJJ15_RS12440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JJJ15_RS12445	COG1126	abc transporter atp-binding protein
JJJ15_RS12450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JJJ15_RS12455	COG0765	amino acid transport
JJJ15_RS12460	COG0765	amino acid transport
JJJ15_RS12465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JJJ15_RS12480	COG1131	(ABC) transporter
JJJ15_RS12520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JJJ15_RS12530	COG1438	arginine binding
JJJ15_RS12535	COG0137	argininosuccinate synthase activity
JJJ15_RS12555	COG0165	Argininosuccinate lyase
JJJ15_RS12560	COG2094	Belongs to the DNA glycosylase MPG family
JJJ15_RS12575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JJJ15_RS12615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JJJ15_RS12620	COG0497	DNA recombination
JJJ15_RS12650	COG0504	CTP synthase activity
JJJ15_RS12655	COG0494	nUDIX hydrolase
JJJ15_RS12675	COG0396	ATPase activity
JJJ15_RS12680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JJJ15_RS12685	COG0822	iron-sulfur transferase activity
JJJ15_RS12690	COG2151	metal-sulfur cluster biosynthetic enzyme
JJJ15_RS12695	COG3189	MarR family transcriptional regulator
JJJ15_RS12715	COG0167	dihydroorotate dehydrogenase activity
JJJ15_RS12720	COG0667	Aldo Keto reductase
JJJ15_RS12745	COG0366	Alpha amylase catalytic
JJJ15_RS12745	COG3103	Sh3 type 3 domain protein
JJJ15_RS12750	COG3833	ABC-type maltose transport systems, permease component
JJJ15_RS12755	COG1175	transmembrane transport
JJJ15_RS12760	COG2182	Extracellular solute-binding protein