locus-tag	class	description
AM609_RS00015	COG1136	(ABC) transporter
AM609_RS00015	COG0577	efflux transmembrane transporter activity
AM609_RS00020	COG3409	Peptidoglycan-binding domain 1 protein
AM609_RS00050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM609_RS00065	COG3716	PTS system mannose fructose sorbose family IID component
AM609_RS00070	COG3715	PTS system
AM609_RS00080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM609_RS00140	COG1132	(ABC) transporter
AM609_RS00145	COG1132	(ABC) transporter
AM609_RS00150	COG2826	transposase and inactivated derivatives, IS30 family
AM609_RS00165	COG1940	carbohydrate kinase activity
AM609_RS00180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM609_RS00200	COG1643	Atp-dependent helicase
AM609_RS00220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM609_RS00225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM609_RS00245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM609_RS00250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM609_RS00255	COG3142	Participates in the control of copper homeostasis
AM609_RS00270	COG1132	(ABC) transporter
AM609_RS00275	COG1132	(ABC) transporter
AM609_RS00290	COG0714	Associated with various cellular activities
AM609_RS00305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM609_RS00330	COG2860	membrane
AM609_RS00340	COG3878	Protein conserved in bacteria
AM609_RS00350	COG5650	phosphatidylinositol metabolic process
AM609_RS00365	COG0631	protein serine/threonine phosphatase activity
AM609_RS00390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM609_RS00440	COG0542	response to heat
AM609_RS00470	COG0515	serine threonine protein kinase
AM609_RS00505	COG0443	Heat shock 70 kDa protein
AM609_RS00690	COG3842	ATPase activity
AM609_RS00715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM609_RS00720	COG0601	transmembrane transport
AM609_RS00725	COG0747	negative chemotaxis
AM609_RS00760	COG2304	oxidoreductase activity
AM609_RS00780	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AM609_RS00780	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AM609_RS00785	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AM609_RS00785	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AM609_RS00800	COG0714	Associated with various cellular activities
AM609_RS00835	COG0494	nUDIX hydrolase
AM609_RS00865	COG0717	Belongs to the dCTP deaminase family
AM609_RS00880	COG0778	Nitroreductase
AM609_RS00895	COG4221	oxidoreductase activity
AM609_RS00905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM609_RS00930	COG0191	fructose-bisphosphate aldolase activity
AM609_RS00965	COG3293	Transposase
AM609_RS00970	COG2272	Belongs to the type-B carboxylesterase lipase family
AM609_RS00980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM609_RS01015	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AM609_RS01050	COG0151	Belongs to the GarS family
AM609_RS01055	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM609_RS01065	COG0047	phosphoribosylformylglycinamidine synthase activity
AM609_RS01080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM609_RS01120	COG0546	phosphoglycolate phosphatase activity
AM609_RS01165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM609_RS01175	COG1349	DNA-binding transcription factor activity
AM609_RS01180	COG1105	Belongs to the carbohydrate kinase PfkB family
AM609_RS01200	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM609_RS01235	COG2226	methyltransferase
AM609_RS01240	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM609_RS01245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM609_RS01280	COG1132	(ABC) transporter
AM609_RS01285	COG1132	(ABC) transporter
AM609_RS01290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM609_RS01300	COG1120	ATPase activity
AM609_RS01305	COG0577	efflux transmembrane transporter activity
AM609_RS01305	COG1136	(ABC) transporter
AM609_RS01310	COG1136	(ABC) transporter
AM609_RS01310	COG0577	efflux transmembrane transporter activity
AM609_RS01335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM609_RS01365	COG1136	(ABC) transporter
AM609_RS01390	COG1556	Lactate utilization protein
AM609_RS01395	COG1139	Iron-sulfur cluster binding protein
AM609_RS01400	COG0247	lactate metabolic process
AM609_RS01445	COG0714	Associated with various cellular activities
AM609_RS01455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AM609_RS01455	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AM609_RS01460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM609_RS01480	COG0438	transferase activity, transferring glycosyl groups
AM609_RS01520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM609_RS01525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM609_RS01535	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM609_RS01550	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AM609_RS01555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM609_RS01580	COG1846	Transcriptional regulator
AM609_RS01580	COG1940	carbohydrate kinase activity
AM609_RS01630	COG2017	converts alpha-aldose to the beta-anomer
AM609_RS01655	COG3250	beta-galactosidase activity
AM609_RS01670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM609_RS01680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM609_RS01685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM609_RS01695	COG1115	amino acid carrier protein
AM609_RS01700	COG0436	Aminotransferase
AM609_RS01730	COG0250	Participates in transcription elongation, termination and antitermination
AM609_RS01735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM609_RS01740	COG0081	regulation of translation
AM609_RS01745	COG0515	serine threonine protein kinase
AM609_RS01750	COG2885	chlorophyll binding
AM609_RS01760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM609_RS01765	COG0222	ribosome binding
AM609_RS01770	COG0085	RNA polymerase activity
AM609_RS01775	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM609_RS01785	COG0443	Heat shock 70 kDa protein
AM609_RS01835	COG0443	Heat shock 70 kDa protein
AM609_RS01880	COG1100	Small GTP-binding protein
AM609_RS01885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM609_RS01890	COG0049	tRNA binding
AM609_RS01895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM609_RS01900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM609_RS01920	COG0051	transcription antitermination factor activity, RNA binding
AM609_RS01925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM609_RS01935	COG0089	rRNA binding
AM609_RS01940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM609_RS01945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM609_RS01955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM609_RS01960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM609_RS01965	COG0255	Belongs to the universal ribosomal protein uL29 family
AM609_RS01970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM609_RS01980	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM609_RS01985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM609_RS01990	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM609_RS01995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM609_RS02005	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM609_RS02015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM609_RS02020	COG1841	ribosomal large subunit assembly
AM609_RS02045	COG0563	adenylate kinase activity
AM609_RS02050	COG0024	Methionine aminopeptidase
AM609_RS02055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM609_RS02060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM609_RS02065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM609_RS02070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM609_RS02075	COG0202	RNA polymerase activity
AM609_RS02080	COG0203	ribosomal protein L17
AM609_RS02095	COG0101	tRNA pseudouridine synthase activity
AM609_RS02100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM609_RS02105	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM609_RS02140	COG1072	(Pantothenic acid kinase))
AM609_RS02145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM609_RS02150	COG0736	holo-[acyl-carrier-protein] synthase activity
AM609_RS02160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM609_RS02165	COG0802	atpase or kinase
AM609_RS02185	COG1053	succinate dehydrogenase
AM609_RS02190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM609_RS02195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM609_RS02200	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AM609_RS02210	COG2949	membrane
AM609_RS02215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM609_RS02240	COG0516	GMP reductase activity
AM609_RS02245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM609_RS02250	COG2095	MarC family integral membrane protein
AM609_RS02255	COG0328	RNA-DNA hybrid ribonuclease activity
AM609_RS02260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM609_RS02270	COG2814	Major facilitator Superfamily
AM609_RS02290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM609_RS02290	COG0519	Catalyzes the synthesis of GMP from XMP
AM609_RS02310	COG0667	Aldo Keto reductase
AM609_RS02335	COG1131	(ABC) transporter
AM609_RS02340	COG4585	Histidine kinase
AM609_RS02345	COG2197	response regulator
AM609_RS02375	COG0583	DNA-binding transcription factor activity
AM609_RS02400	COG1129	ABC transporter
AM609_RS02420	COG3541	Predicted nucleotidyltransferase
AM609_RS02445	COG2814	Major facilitator Superfamily
AM609_RS02455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM609_RS02470	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM609_RS02480	COG1609	Transcriptional regulator
AM609_RS02485	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM609_RS02535	COG2197	response regulator
AM609_RS02545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM609_RS02555	COG0356	it plays a direct role in the translocation of protons across the membrane
AM609_RS02560	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM609_RS02565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM609_RS02570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM609_RS02575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM609_RS02580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM609_RS02585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM609_RS02590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM609_RS02605	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AM609_RS02685	COG1129	ABC transporter
AM609_RS02700	COG3328	transposase activity
AM609_RS02705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM609_RS02710	COG1518	maintenance of DNA repeat elements
AM609_RS02725	COG1857	crispr-associated protein
AM609_RS02750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM609_RS02765	COG0549	Belongs to the carbamate kinase family
AM609_RS02790	COG3328	transposase activity
AM609_RS02795	COG0577	efflux transmembrane transporter activity
AM609_RS02795	COG1136	(ABC) transporter
AM609_RS02800	COG0577	efflux transmembrane transporter activity
AM609_RS02800	COG1136	(ABC) transporter
AM609_RS02810	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM609_RS02830	COG1744	ABC transporter substrate-binding protein PnrA-like
AM609_RS02835	COG3845	ABC transporter
AM609_RS02840	COG4603	Belongs to the binding-protein-dependent transport system permease family
AM609_RS02845	COG1079	Belongs to the binding-protein-dependent transport system permease family
AM609_RS02865	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM609_RS02870	COG1121	(ABC) transporter
AM609_RS02885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM609_RS02915	COG1611	Belongs to the LOG family
AM609_RS02920	COG4122	O-methyltransferase activity
AM609_RS02925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM609_RS02930	COG2151	metal-sulfur cluster biosynthetic enzyme
AM609_RS02930	COG0489	protein tyrosine kinase activity
AM609_RS02935	COG2755	lipolytic protein G-D-S-L family
AM609_RS02935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM609_RS02945	COG2239	Acts as a magnesium transporter
AM609_RS02955	COG1082	Xylose isomerase domain protein TIM barrel
AM609_RS02970	COG0006	proline dipeptidase activity
AM609_RS02975	COG0673	inositol 2-dehydrogenase activity
AM609_RS02985	COG2095	MarC family integral membrane protein
AM609_RS02990	COG0513	Belongs to the DEAD box helicase family
AM609_RS03015	COG0210	DNA helicase
AM609_RS03065	COG0583	DNA-binding transcription factor activity
AM609_RS03070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM609_RS03100	COG1136	(ABC) transporter
AM609_RS03110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM609_RS03115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM609_RS03130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM609_RS03135	COG2188	Transcriptional regulator
AM609_RS03140	COG1263	PTS System
AM609_RS03160	COG1929	Belongs to the glycerate kinase type-1 family
AM609_RS03165	COG3590	peptidase
AM609_RS03190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM609_RS03195	COG0154	amidase activity
AM609_RS03200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM609_RS03230	COG1175	transmembrane transport
AM609_RS03235	COG0395	ABC-type sugar transport system, permease component
AM609_RS03240	COG1621	beta-fructofuranosidase activity
AM609_RS03245	COG1609	Transcriptional regulator
AM609_RS03255	COG2985	domain, Protein
AM609_RS03255	COG0569	domain protein
AM609_RS03270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM609_RS03300	COG0473	3-isopropylmalate dehydrogenase activity
AM609_RS03305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM609_RS03310	COG1316	TRANSCRIPTIONal
AM609_RS03335	COG1442	glycosyl transferase family 8
AM609_RS03335	COG1216	Glycosyl transferase, family 2
AM609_RS03340	COG1216	Glycosyl transferase, family 2
AM609_RS03355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM609_RS03410	COG0842	Transport permease protein
AM609_RS03410	COG1716	ATPase activity
AM609_RS03410	COG1131	(ABC) transporter
AM609_RS03425	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM609_RS03430	COG0629	single-stranded DNA binding
AM609_RS03440	COG2884	Cell division ATP-binding protein ftsE
AM609_RS03445	COG2177	Part of the ABC transporter FtsEX involved in
AM609_RS03460	COG0667	Aldo Keto reductase
AM609_RS03465	COG2233	PERMEase
AM609_RS03470	COG2188	Transcriptional regulator
AM609_RS03475	COG0747	negative chemotaxis
AM609_RS03485	COG0444	Belongs to the ABC transporter superfamily
AM609_RS03490	COG4608	Belongs to the ABC transporter superfamily
AM609_RS03495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM609_RS03500	COG1940	carbohydrate kinase activity
AM609_RS03505	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM609_RS03525	COG0363	glucosamine-6-phosphate deaminase activity
AM609_RS03550	COG3547	Transposase (IS116 IS110 IS902 family)
AM609_RS03560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM609_RS03570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM609_RS03590	COG0442	prolyl-tRNA aminoacylation
AM609_RS03610	COG0779	Required for maturation of 30S ribosomal subunits
AM609_RS03625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM609_RS03625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM609_RS03640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM609_RS03645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM609_RS03650	COG1309	transcriptional regulator
AM609_RS03655	COG0196	riboflavin kinase activity
AM609_RS03670	COG1136	(ABC) transporter
AM609_RS03670	COG0577	efflux transmembrane transporter activity
AM609_RS03685	COG1185	polyribonucleotide nucleotidyltransferase activity
AM609_RS03690	COG0612	Peptidase, M16
AM609_RS03695	COG0300	oxidoreductase activity
AM609_RS03705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM609_RS03730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM609_RS03735	COG0318	PFAM AMP-dependent synthetase and ligase
AM609_RS03740	COG0318	PFAM AMP-dependent synthetase and ligase
AM609_RS03760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM609_RS03770	COG2001	Belongs to the MraZ family
AM609_RS03775	COG0275	rRNA processing
AM609_RS03785	COG0768	penicillin binding
AM609_RS03790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM609_RS03795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM609_RS03800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM609_RS03805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM609_RS03820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM609_RS03835	COG1496	oxidoreductase activity
AM609_RS03840	COG1799	cell septum assembly
AM609_RS03850	COG3599	regulation of cell shape
AM609_RS03855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM609_RS03870	COG0587	DNA-directed DNA polymerase activity
AM609_RS03875	COG2501	S4 domain
AM609_RS03955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM609_RS03975	COG0514	ATP-dependent DNA helicase (RecQ)
AM609_RS04000	COG2078	PFAM AMMECR1 domain protein
AM609_RS04005	COG1355	regulation of microtubule-based process
AM609_RS04015	COG0131	Imidazoleglycerol-phosphate dehydratase
AM609_RS04030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM609_RS04035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM609_RS04055	COG2963	transposase activity
AM609_RS04065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM609_RS04070	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM609_RS04075	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM609_RS04080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM609_RS04105	COG1126	abc transporter atp-binding protein
AM609_RS04110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM609_RS04115	COG0765	amino acid transport
AM609_RS04120	COG0765	amino acid transport
AM609_RS04125	COG2814	Major facilitator Superfamily
AM609_RS04185	COG3304	Inner membrane component domain
AM609_RS04190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM609_RS04205	COG1115	amino acid carrier protein
AM609_RS04210	COG1115	amino acid carrier protein
AM609_RS04215	COG1115	amino acid carrier protein
AM609_RS04220	COG1115	amino acid carrier protein
AM609_RS04225	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM609_RS04240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM609_RS04265	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AM609_RS04275	COG1674	ftsk spoiiie
AM609_RS04290	COG1058	Belongs to the CinA family
AM609_RS04290	COG1546	Belongs to the CinA family
AM609_RS04295	COG1396	sequence-specific DNA binding
AM609_RS04305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM609_RS04310	COG2137	regulation of response to DNA damage stimulus
AM609_RS04315	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AM609_RS04325	COG1252	NADH dehydrogenase
AM609_RS04330	COG0509	glycine decarboxylation via glycine cleavage system
AM609_RS04335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM609_RS04340	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM609_RS04340	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM609_RS04350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM609_RS04365	COG2188	Transcriptional regulator
AM609_RS04385	COG0672	)-iron permease
AM609_RS04390	COG3470	protein probably involved in high-affinity Fe2 transport
AM609_RS04405	COG0577	efflux transmembrane transporter activity
AM609_RS04410	COG1136	(ABC) transporter
AM609_RS04410	COG0577	efflux transmembrane transporter activity
AM609_RS04430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM609_RS04455	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM609_RS04475	COG2813	Specifically methylates the guanine in position
AM609_RS04485	COG1114	Component of the transport system for branched-chain amino acids
AM609_RS04490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM609_RS04505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM609_RS04530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM609_RS04550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM609_RS04555	COG0066	3-isopropylmalate dehydratase activity
AM609_RS04560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM609_RS04570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM609_RS04600	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM609_RS04630	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM609_RS04635	COG1461	Dihydroxyacetone kinase
AM609_RS04650	COG0742	ribosomal rna small subunit methyltransferase
AM609_RS04660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM609_RS04675	COG0571	ribonuclease III activity
AM609_RS04680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AM609_RS04705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM609_RS04710	COG4988	ABC transporter
AM609_RS04715	COG1294	oxidase, subunit
AM609_RS04720	COG1271	oxidase subunit
AM609_RS04725	COG1530	ribonuclease E activity
AM609_RS04730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM609_RS04735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM609_RS04740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM609_RS04745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM609_RS04795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM609_RS04800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM609_RS04810	COG0745	RESPONSE REGULATOR receiver
AM609_RS04815	COG5002	protein histidine kinase activity
AM609_RS04835	COG1132	(ABC) transporter
AM609_RS04845	COG0438	transferase activity, transferring glycosyl groups
AM609_RS04855	COG1349	DNA-binding transcription factor activity
AM609_RS04860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM609_RS04875	COG0799	negative regulation of ribosome biogenesis
AM609_RS04880	COG0406	alpha-ribazole phosphatase activity
AM609_RS04935	COG0733	neurotransmitter:sodium symporter activity
AM609_RS04960	COG0537	adenosine 5'-monophosphoramidase activity
AM609_RS04965	COG0495	leucyl-tRNA aminoacylation
AM609_RS04980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM609_RS04995	COG1307	EDD domain protein, DegV family
AM609_RS05015	COG4868	Belongs to the UPF0371 family
AM609_RS05020	COG0268	Binds directly to 16S ribosomal RNA
AM609_RS05045	COG1136	(ABC) transporter
AM609_RS05045	COG0577	efflux transmembrane transporter activity
AM609_RS05055	COG2197	response regulator
AM609_RS05075	COG4585	Histidine kinase
AM609_RS05080	COG2197	response regulator
AM609_RS05085	COG0159	tryptophan synthase activity
AM609_RS05100	COG0159	tryptophan synthase activity
AM609_RS05110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM609_RS05115	COG0512	Glutamine amidotransferase of anthranilate synthase
AM609_RS05120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM609_RS05135	COG1216	Glycosyl transferase, family 2
AM609_RS05145	COG0481	GTPase activity
AM609_RS05155	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM609_RS05185	COG1420	regulation of RNA biosynthetic process
AM609_RS05190	COG0484	heat shock protein binding
AM609_RS05240	COG0640	Transcriptional regulator
AM609_RS05255	COG0443	Heat shock 70 kDa protein
AM609_RS05265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM609_RS05275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM609_RS05285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM609_RS05285	COG0506	proline dehydrogenase activity
AM609_RS05285	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM609_RS05290	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM609_RS05295	COG3609	addiction module antidote protein, CC2985 family
AM609_RS05305	COG1476	TRANSCRIPTIONal
AM609_RS05315	COG1131	(ABC) transporter
AM609_RS05325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM609_RS05330	COG1381	Involved in DNA repair and RecF pathway recombination
AM609_RS05335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM609_RS05340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM609_RS05345	COG1121	(ABC) transporter
AM609_RS05355	COG0423	glycine-tRNA ligase activity
AM609_RS05380	COG0560	Phosphoserine phosphatase
AM609_RS05390	COG0297	glycogen (starch) synthase activity
AM609_RS05400	COG1119	ATPase activity
AM609_RS05430	COG2326	polyphosphate kinase activity
AM609_RS05445	COG0488	(ABC) transporter
AM609_RS05460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM609_RS05500	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AM609_RS05510	COG0515	serine threonine protein kinase
AM609_RS05510	COG2815	serine threonine protein kinase
AM609_RS05515	COG0142	geranyltranstransferase activity
AM609_RS05520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM609_RS05540	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM609_RS05590	COG0569	domain protein
AM609_RS05595	COG0531	amino acid
AM609_RS05600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM609_RS05610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM609_RS05620	COG2197	response regulator
AM609_RS05650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM609_RS05665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM609_RS05670	COG4221	oxidoreductase activity
AM609_RS05675	COG1881	PFAM PEBP family protein
AM609_RS05685	COG1435	thymidine kinase activity
AM609_RS05700	COG0676	glucose-6-phosphate 1-epimerase activity
AM609_RS05720	COG0477	Major facilitator Superfamily
AM609_RS05725	COG0339	signal peptide processing
AM609_RS05730	COG1252	NADH dehydrogenase
AM609_RS05740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM609_RS05745	COG4605	iron ion homeostasis
AM609_RS05755	COG0667	Aldo Keto reductase
AM609_RS05765	COG1994	Peptidase M50
AM609_RS05765	COG0517	IMP dehydrogenase activity
AM609_RS05775	COG2264	protein methyltransferase activity
AM609_RS05785	COG1222	aaa ATPase
AM609_RS05790	COG4122	O-methyltransferase activity
AM609_RS05800	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AM609_RS05815	COG0107	imidazoleglycerol-phosphate synthase activity
AM609_RS05820	COG0134	indole-3-glycerol-phosphate synthase activity
AM609_RS05825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM609_RS05855	COG0539	negative regulation of cytoplasmic translation
AM609_RS05865	COG0237	dephospho-CoA kinase activity
AM609_RS05870	COG0556	nucleotide-excision repair
AM609_RS05890	COG1012	belongs to the aldehyde dehydrogenase family
AM609_RS05950	COG0322	excinuclease ABC activity
AM609_RS05955	COG3585	molybdate ion transport
AM609_RS05970	COG1660	Displays ATPase and GTPase activities
AM609_RS05975	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM609_RS05980	COG1481	regulation of sporulation
AM609_RS05985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM609_RS05995	COG0149	triose-phosphate isomerase activity
AM609_RS06000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM609_RS06020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AM609_RS06045	COG1160	GTP binding
AM609_RS06060	COG0166	Belongs to the GPI family
AM609_RS06140	COG1136	(ABC) transporter
AM609_RS06165	COG0383	alpha-mannosidase activity
AM609_RS06170	COG3842	ATPase activity
AM609_RS06175	COG0395	ABC-type sugar transport system, permease component
AM609_RS06180	COG1175	transmembrane transport
AM609_RS06195	COG1082	Xylose isomerase domain protein TIM barrel
AM609_RS06210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM609_RS06365	COG1674	ftsk spoiiie
AM609_RS06365	COG0433	COG0433 Predicted ATPase
AM609_RS06380	COG0515	serine threonine protein kinase
AM609_RS06455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM609_RS06485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM609_RS06490	COG1716	ATPase activity
AM609_RS06525	COG1621	beta-fructofuranosidase activity
AM609_RS06530	COG1263	PTS System
AM609_RS06530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM609_RS06530	COG2190	(PTS) system
AM609_RS06555	COG0577	efflux transmembrane transporter activity
AM609_RS06575	COG0477	Major facilitator Superfamily
AM609_RS06610	COG0205	6-phosphofructokinase activity
AM609_RS06620	COG1216	Glycosyl transferase, family 2
AM609_RS06645	COG0805	protein transport
AM609_RS06650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM609_RS06670	COG0140	phosphoribosyl-ATP diphosphatase activity
AM609_RS06675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM609_RS06685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM609_RS06690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM609_RS06695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM609_RS06700	COG2002	toxin-antitoxin pair type II binding
AM609_RS06710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM609_RS06715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM609_RS06720	COG4770	biotin carboxylase activity
AM609_RS06765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM609_RS06775	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM609_RS06790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM609_RS06800	COG1758	RNA polymerase activity
AM609_RS06805	COG0194	GDP metabolic process
AM609_RS06810	COG0284	orotidine-5'-phosphate decarboxylase activity
AM609_RS06815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM609_RS06825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM609_RS06830	COG0540	Belongs to the ATCase OTCase family
AM609_RS06835	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AM609_RS06845	COG0702	epimerase
AM609_RS06850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM609_RS06855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM609_RS06865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM609_RS06870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM609_RS06875	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM609_RS06880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM609_RS06890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM609_RS06900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM609_RS06905	COG0730	response to heat
AM609_RS06915	COG2409	Drug exporters of the RND superfamily
AM609_RS06945	COG0009	L-threonylcarbamoyladenylate synthase
AM609_RS06960	COG1063	alcohol dehydrogenase
AM609_RS06980	COG5265	(ABC) transporter
AM609_RS06985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM609_RS07010	COG1116	anion transmembrane transporter activity
AM609_RS07010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM609_RS07035	COG0124	histidyl-tRNA synthetase
AM609_RS07050	COG0488	(ABC) transporter
AM609_RS07055	COG1196	nuclear chromosome segregation
AM609_RS07065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM609_RS07070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM609_RS07075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM609_RS07080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM609_RS07090	COG2255	four-way junction helicase activity
AM609_RS07095	COG0632	four-way junction helicase activity
AM609_RS07100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM609_RS07105	COG0217	transcriptional regulatory protein
AM609_RS07125	COG0438	transferase activity, transferring glycosyl groups
AM609_RS07130	COG1560	Kdo2-lipid A biosynthetic process
AM609_RS07135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM609_RS07145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM609_RS07185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM609_RS07200	COG1882	Formate acetyltransferase
AM609_RS07230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM609_RS07235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM609_RS07265	COG0321	lipoyl(octanoyl) transferase activity
AM609_RS07270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM609_RS07290	COG0765	amino acid transport
AM609_RS07315	COG0406	alpha-ribazole phosphatase activity
AM609_RS07320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM609_RS07325	COG0174	glutamine synthetase
AM609_RS07330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM609_RS07335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM609_RS07335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM609_RS07405	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AM609_RS07410	COG0436	Aminotransferase
AM609_RS07435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM609_RS07440	COG1027	Aspartate ammonia-lyase
AM609_RS07450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM609_RS07495	COG0358	DNA primase activity
AM609_RS07515	COG2182	Extracellular solute-binding protein
AM609_RS07525	COG3833	ABC-type maltose transport systems, permease component
AM609_RS07530	COG0366	Alpha amylase catalytic
AM609_RS07530	COG3103	Sh3 type 3 domain protein
AM609_RS07535	COG1609	Transcriptional regulator
AM609_RS07540	COG1929	Belongs to the glycerate kinase type-1 family
AM609_RS07555	COG0667	Aldo Keto reductase
AM609_RS07580	COG0167	dihydroorotate dehydrogenase activity
AM609_RS07610	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM609_RS07625	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AM609_RS07630	COG2151	metal-sulfur cluster biosynthetic enzyme
AM609_RS07635	COG0822	iron-sulfur transferase activity
AM609_RS07645	COG0396	ATPase activity
AM609_RS07670	COG1609	Transcriptional regulator
AM609_RS07675	COG0395	ABC-type sugar transport system, permease component
AM609_RS07680	COG1175	transmembrane transport
AM609_RS07725	COG0497	DNA recombination
AM609_RS07730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM609_RS07745	COG0647	UMP catabolic process
AM609_RS07770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM609_RS07790	COG2094	Belongs to the DNA glycosylase MPG family
AM609_RS07795	COG0165	Argininosuccinate lyase
AM609_RS07810	COG0137	argininosuccinate synthase activity
AM609_RS07815	COG1438	arginine binding
AM609_RS07825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM609_RS07835	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM609_RS07865	COG1131	(ABC) transporter
AM609_RS07880	COG1175	transmembrane transport
AM609_RS07905	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM609_RS07910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM609_RS07915	COG0454	-acetyltransferase
AM609_RS07915	COG0456	acetyltransferase
AM609_RS07920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM609_RS07965	COG0750	zinc metalloprotease
AM609_RS07970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM609_RS07980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM609_RS07990	COG0233	cytoplasmic translational termination
AM609_RS08000	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM609_RS08005	COG0052	Belongs to the universal ribosomal protein uS2 family
AM609_RS08030	COG0792	nuclease activity
AM609_RS08040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM609_RS08045	COG0681	Belongs to the peptidase S26 family
AM609_RS08050	COG0335	large ribosomal subunit rRNA binding
AM609_RS08055	COG0681	Belongs to the peptidase S26 family
AM609_RS08060	COG0336	Belongs to the RNA methyltransferase TrmD family
AM609_RS08065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM609_RS08070	COG1837	Belongs to the UPF0109 family
AM609_RS08075	COG0228	four-way junction DNA binding
AM609_RS08090	COG1131	(ABC) transporter
AM609_RS08100	COG4585	Histidine kinase
AM609_RS08105	COG2197	response regulator
AM609_RS08110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM609_RS08120	COG1131	(ABC) transporter
AM609_RS08125	COG0842	Transport permease protein
AM609_RS08130	COG4585	Histidine kinase
AM609_RS08135	COG2197	response regulator
AM609_RS08150	COG1196	nuclear chromosome segregation
AM609_RS08155	COG4585	Histidine kinase
AM609_RS08160	COG2197	response regulator
AM609_RS08170	COG1131	(ABC) transporter
AM609_RS08185	COG4152	abc transporter atp-binding protein
AM609_RS08195	COG0105	UTP biosynthetic process
AM609_RS08205	COG1461	Dihydroxyacetone kinase
AM609_RS08210	COG0285	dihydrofolate synthase activity
AM609_RS08215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM609_RS08235	COG0438	transferase activity, transferring glycosyl groups
AM609_RS08355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM609_RS08360	COG2188	Transcriptional regulator
AM609_RS08365	COG2190	(PTS) system
AM609_RS08365	COG1263	PTS System
AM609_RS08365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM609_RS08370	COG0366	Alpha amylase catalytic
AM609_RS08395	COG4115	mRNA cleavage
AM609_RS08400	COG2161	toxin-antitoxin pair type II binding
AM609_RS08410	COG3177	Filamentation induced by cAMP protein fic
AM609_RS08425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM609_RS08430	COG1129	ABC transporter
AM609_RS08460	COG1605	Chorismate mutase
AM609_RS08460	COG0287	Prephenate dehydrogenase
AM609_RS08465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM609_RS08470	COG0740	serine-type endopeptidase activity
AM609_RS08475	COG0740	serine-type endopeptidase activity
AM609_RS08480	COG1116	anion transmembrane transporter activity
AM609_RS08525	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM609_RS08535	COG0738	Major facilitator superfamily
AM609_RS08600	COG2963	transposase activity
AM609_RS08655	COG1739	Uncharacterized protein family UPF0029
AM609_RS08665	COG1045	serine acetyltransferase
AM609_RS08670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM609_RS08710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM609_RS08720	COG1732	Glycine betaine
AM609_RS08730	COG1174	glycine betaine transport
AM609_RS08745	COG0604	alcohol dehydrogenase
AM609_RS08745	COG3321	synthase
AM609_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
AM609_RS08760	COG0346	lactoylglutathione lyase activity
AM609_RS08770	COG1136	(ABC) transporter
AM609_RS08770	COG0577	efflux transmembrane transporter activity
AM609_RS08775	COG2205	protein histidine kinase activity
AM609_RS08790	COG0114	fumarate hydratase activity
AM609_RS08795	COG2315	Protein conserved in bacteria
AM609_RS08815	COG2197	response regulator
AM609_RS08835	COG1615	UPF0182 protein
AM609_RS08850	COG3480	Lon protease (S16) C-terminal proteolytic domain
AM609_RS08915	COG4555	ABC transporter
AM609_RS08920	COG0482	sulfurtransferase activity
AM609_RS08930	COG1131	(ABC) transporter
AM609_RS08935	COG1725	Transcriptional regulator
AM609_RS08960	COG3831	ATPase activity
AM609_RS08980	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM609_RS08990	COG0714	Associated with various cellular activities
AM609_RS09000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM609_RS09005	COG2086	electron transfer activity
AM609_RS09020	COG1234	tRNA 3'-trailer cleavage
AM609_RS09030	COG0180	Tryptophanyl-tRNA synthetase
AM609_RS09040	COG0366	Alpha amylase catalytic
AM609_RS09045	COG3281	Trehalose synthase
AM609_RS09050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM609_RS09055	COG0058	SHG alpha-glucan phosphorylase activity
AM609_RS09095	COG0039	L-malate dehydrogenase activity
AM609_RS09125	COG0045	succinate-CoA ligase (ADP-forming) activity
AM609_RS09135	COG0205	6-phosphofructokinase activity
AM609_RS09190	COG1609	Transcriptional regulator
AM609_RS09195	COG3250	beta-galactosidase activity
AM609_RS09215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM609_RS09220	COG0366	Alpha amylase catalytic
AM609_RS09230	COG1175	transmembrane transport
AM609_RS09240	COG1846	Transcriptional regulator
AM609_RS09240	COG1940	carbohydrate kinase activity
AM609_RS09245	COG1501	Belongs to the glycosyl hydrolase 31 family
AM609_RS09250	COG1609	Transcriptional regulator
AM609_RS09260	COG1175	transmembrane transport
AM609_RS09265	COG0395	ABC-type sugar transport system, permease component
AM609_RS09270	COG1501	Belongs to the glycosyl hydrolase 31 family
AM609_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
AM609_RS09305	COG3293	Transposase
AM609_RS09345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM609_RS09350	COG0254	rRNA binding
AM609_RS09370	COG0083	homoserine kinase activity
AM609_RS09375	COG0460	homoserine dehydrogenase
AM609_RS09385	COG4172	Belongs to the ABC transporter superfamily
AM609_RS09400	COG1132	(ABC) transporter
AM609_RS09440	COG0019	diaminopimelate decarboxylase activity
AM609_RS09445	COG0018	arginyl-trna synthetase
AM609_RS09480	COG2272	Belongs to the type-B carboxylesterase lipase family
AM609_RS09485	COG0584	glycerophosphoryl diester phosphodiesterase
AM609_RS09510	COG1253	flavin adenine dinucleotide binding
AM609_RS09520	COG0567	Dehydrogenase, E1 component
AM609_RS09520	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM609_RS09550	COG1309	transcriptional regulator
AM609_RS09555	COG1131	(ABC) transporter
AM609_RS09565	COG5662	AntiSigma factor
AM609_RS09570	COG1595	DNA-templated transcription, initiation
AM609_RS09580	COG2838	Isocitrate dehydrogenase
AM609_RS09585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM609_RS09590	COG1162	GTPase activity
AM609_RS09620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM609_RS09630	COG0314	molybdopterin synthase activity
AM609_RS09640	COG0315	cyclic pyranopterin monophosphate synthase activity
AM609_RS09650	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM609_RS09650	COG0315	cyclic pyranopterin monophosphate synthase activity
AM609_RS09665	COG1140	nitrate reductase beta subunit
AM609_RS09705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM609_RS09710	COG1063	alcohol dehydrogenase
AM609_RS09730	COG0483	inositol monophosphate 1-phosphatase activity
AM609_RS09735	COG1968	undecaprenyl-diphosphatase activity
AM609_RS09770	COG0420	3'-5' exonuclease activity
AM609_RS09775	COG0419	ATPase involved in DNA repair
AM609_RS09815	COG0653	protein targeting
AM609_RS09820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM609_RS09825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM609_RS09835	COG5002	protein histidine kinase activity
AM609_RS09835	COG5000	phosphorelay sensor kinase activity
AM609_RS09840	COG0745	RESPONSE REGULATOR receiver
AM609_RS09860	COG0714	Associated with various cellular activities
AM609_RS09865	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AM609_RS09910	COG1482	cell wall glycoprotein biosynthetic process
AM609_RS09995	COG0697	spore germination
AM609_RS10030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM609_RS10060	COG0438	transferase activity, transferring glycosyl groups
AM609_RS10100	COG1316	TRANSCRIPTIONal
AM609_RS10105	COG1316	TRANSCRIPTIONal
AM609_RS10110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM609_RS10115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM609_RS10145	COG0586	Pfam SNARE associated Golgi protein
AM609_RS10150	COG5002	protein histidine kinase activity
AM609_RS10155	COG0745	RESPONSE REGULATOR receiver
AM609_RS10195	COG2205	protein histidine kinase activity
AM609_RS10200	COG0745	RESPONSE REGULATOR receiver
AM609_RS10210	COG0424	maF-like protein
AM609_RS10260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM609_RS10270	COG0501	Belongs to the peptidase M48B family
AM609_RS10275	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AM609_RS10360	COG0686	Belongs to the AlaDH PNT family
AM609_RS10375	COG0142	geranyltranstransferase activity
AM609_RS10380	COG1007	ATP synthesis coupled electron transport
AM609_RS10390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM609_RS10395	COG0713	ATP synthesis coupled electron transport
AM609_RS10405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM609_RS10410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM609_RS10415	COG1034	ATP synthesis coupled electron transport
AM609_RS10420	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM609_RS10430	COG0649	NAD binding
AM609_RS10435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM609_RS10440	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM609_RS10465	COG2226	methyltransferase
AM609_RS10470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM609_RS10475	COG4948	Mandelate Racemase Muconate Lactonizing
AM609_RS10480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM609_RS10500	COG2235	arginine
AM609_RS10515	COG1595	DNA-templated transcription, initiation
AM609_RS10530	COG0758	DNA mediated transformation
AM609_RS10570	COG0406	alpha-ribazole phosphatase activity
AM609_RS10575	COG2171	N-acyltransferase activity
AM609_RS10585	COG1053	succinate dehydrogenase
AM609_RS10610	COG4115	mRNA cleavage
AM609_RS10615	COG2161	toxin-antitoxin pair type II binding
AM609_RS10620	COG2723	6-phospho-beta-galactosidase activity
AM609_RS10650	COG1217	gtp-binding protein TYPA
AM609_RS10685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM609_RS10690	COG0601	transmembrane transport
AM609_RS10700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM609_RS10705	COG0385	Bile acid
AM609_RS10710	COG1268	BioY protein
AM609_RS10740	COG4667	esterase of the alpha-beta hydrolase superfamily
AM609_RS10745	COG1902	pentaerythritol trinitrate reductase activity
AM609_RS10750	COG3012	SEC-C Motif Domain Protein
AM609_RS10755	COG1362	aminopeptidase activity
AM609_RS10815	COG3177	Filamentation induced by cAMP protein fic
AM609_RS10820	COG0698	ribose 5-phosphate isomerase
AM609_RS10830	COG1285	pathogenesis
AM609_RS10885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM609_RS10895	COG3093	addiction module antidote protein HigA
AM609_RS10910	COG0012	GTP binding
AM609_RS10920	COG1322	Protein conserved in bacteria
AM609_RS10935	COG1570	exodeoxyribonuclease VII activity
AM609_RS10940	COG1722	exodeoxyribonuclease VII activity
AM609_RS10950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AM609_RS10955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM609_RS10965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM609_RS10970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM609_RS10985	COG0583	DNA-binding transcription factor activity
AM609_RS11000	COG1695	Transcriptional regulator
AM609_RS11010	COG0431	NADPH-dependent FMN reductase
AM609_RS11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM609_RS11020	COG1073	alpha beta
AM609_RS11035	COG1309	transcriptional regulator
AM609_RS11050	COG0129	dihydroxy-acid dehydratase activity
AM609_RS11055	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM609_RS11100	COG1131	(ABC) transporter
AM609_RS11110	COG4585	Histidine kinase
AM609_RS11115	COG2197	response regulator
AM609_RS11120	COG0193	aminoacyl-tRNA hydrolase activity
AM609_RS11125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM609_RS11130	COG0710	3-dehydroquinate dehydratase activity
AM609_RS11150	COG0148	phosphopyruvate hydratase activity
AM609_RS11175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM609_RS11185	COG1309	transcriptional regulator
AM609_RS11190	COG0488	(ABC) transporter
AM609_RS11195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM609_RS11200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM609_RS11215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM609_RS11260	COG1959	2 iron, 2 sulfur cluster binding
AM609_RS11285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM609_RS11295	COG1970	mechanosensitive ion channel activity
AM609_RS11320	COG3103	Sh3 type 3 domain protein
AM609_RS11320	COG1388	LysM domain
AM609_RS11320	COG0791	NLP P60 protein
AM609_RS11340	COG2252	PERMEase
AM609_RS11345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM609_RS11360	COG1012	belongs to the aldehyde dehydrogenase family
AM609_RS11370	COG0302	gtp cyclohydrolase
AM609_RS11375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM609_RS11465	COG1518	maintenance of DNA repeat elements
AM609_RS11520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM609_RS11530	COG2873	o-acetylhomoserine
AM609_RS11535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM609_RS11540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AM609_RS11570	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM609_RS11575	COG0714	Associated with various cellular activities
AM609_RS11585	COG0574	Belongs to the PEP-utilizing enzyme family
AM609_RS11585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM609_RS11590	COG0477	Major facilitator Superfamily
AM609_RS11620	COG4585	Histidine kinase
AM609_RS11645	COG4585	Histidine kinase
AM609_RS11760	COG0714	Associated with various cellular activities
AM609_RS11795	COG1490	D-aminoacyl-tRNA deacylase activity
AM609_RS11805	COG0354	folic acid binding
AM609_RS11810	COG3485	protocatechuate 3,4-dioxygenase
AM609_RS11820	COG0745	RESPONSE REGULATOR receiver
AM609_RS11830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM609_RS11885	COG0513	Belongs to the DEAD box helicase family
AM609_RS11890	COG3265	gluconokinase activity
AM609_RS11900	COG3293	Transposase
AM609_RS11915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM609_RS11955	COG1121	(ABC) transporter
AM609_RS11970	COG1136	(ABC) transporter
AM609_RS11970	COG0577	efflux transmembrane transporter activity
AM609_RS11975	COG0577	efflux transmembrane transporter activity
AM609_RS11985	COG1472	Belongs to the glycosyl hydrolase 3 family
AM609_RS11990	COG4975	Glucose uptake
AM609_RS12000	COG1061	Type III restriction enzyme res subunit
AM609_RS12030	COG1842	Phage shock protein A
AM609_RS12040	COG0745	RESPONSE REGULATOR receiver
AM609_RS12045	COG2205	protein histidine kinase activity
AM609_RS12070	COG0459	protein refolding
AM609_RS12085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM609_RS12115	COG3842	ATPase activity
AM609_RS12140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM609_RS12145	COG0215	cysteine-tRNA ligase activity
AM609_RS12150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM609_RS12160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM609_RS12205	COG1349	DNA-binding transcription factor activity
AM609_RS12210	COG3104	oligopeptide transport
AM609_RS12220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM609_RS12225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM609_RS12225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM609_RS12225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM609_RS12245	COG1309	transcriptional regulator
AM609_RS12255	COG0542	response to heat
AM609_RS12265	COG3655	Transcriptional regulator
AM609_RS12280	COG1505	serine-type exopeptidase activity
AM609_RS12300	COG0745	RESPONSE REGULATOR receiver
AM609_RS12305	COG2205	protein histidine kinase activity
AM609_RS12310	COG0789	Transcriptional regulator
AM609_RS12315	COG0484	heat shock protein binding
AM609_RS12320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM609_RS12325	COG0443	Heat shock 70 kDa protein
AM609_RS12340	COG1136	(ABC) transporter
AM609_RS12340	COG0577	efflux transmembrane transporter activity
AM609_RS12415	COG0471	metal ion transport
AM609_RS12445	COG3311	Transcriptional regulator
AM609_RS12500	COG1201	RNA secondary structure unwinding
AM609_RS12505	COG0210	DNA helicase
AM609_RS12530	COG1401	restriction endodeoxyribonuclease activity
AM609_RS12585	COG1309	transcriptional regulator
AM609_RS12605	COG2885	chlorophyll binding
AM609_RS12615	COG2205	protein histidine kinase activity
AM609_RS12620	COG0745	RESPONSE REGULATOR receiver
AM609_RS12630	COG1754	DNA topoisomerase type I activity
AM609_RS12630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM609_RS12645	COG0745	RESPONSE REGULATOR receiver
AM609_RS12650	COG2205	protein histidine kinase activity
AM609_RS12655	COG1472	Belongs to the glycosyl hydrolase 3 family
AM609_RS12740	COG0596	Alpha beta hydrolase
AM609_RS12750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM609_RS12760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM609_RS12790	COG1597	lipid kinase activity
AM609_RS12865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM609_RS12880	COG0494	nUDIX hydrolase
AM609_RS12885	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM609_RS12885	COG3253	May function as heme-dependent peroxidase
AM609_RS12890	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM609_RS12895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM609_RS12900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM609_RS12910	COG0181	hydroxymethylbilane synthase activity
AM609_RS12915	COG0113	porphobilinogen synthase activity
AM609_RS12920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM609_RS12925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM609_RS12925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM609_RS12925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM609_RS12935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM609_RS12940	COG2723	6-phospho-beta-galactosidase activity
AM609_RS12970	COG0783	Belongs to the Dps family
AM609_RS12995	COG2197	response regulator
AM609_RS13000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM609_RS13065	COG1131	(ABC) transporter
AM609_RS13085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM609_RS13095	COG2826	transposase and inactivated derivatives, IS30 family
AM609_RS13130	COG3386	PFAM SMP-30 Gluconolaconase
AM609_RS13140	COG3588	fructose-bisphosphate aldolase
AM609_RS13145	COG1609	Transcriptional regulator
AM609_RS13155	COG2211	Major facilitator Superfamily
AM609_RS13165	COG2211	Major facilitator Superfamily
AM609_RS13230	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
AM609_RS13255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM609_RS13285	COG3579	cysteine-type endopeptidase activity
AM609_RS13300	COG1950	PFAM Membrane protein of
AM609_RS13305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM609_RS13315	COG1937	Protein conserved in bacteria
AM609_RS13355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM609_RS13365	COG1737	Transcriptional regulator
AM609_RS13370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM609_RS13395	COG0477	Major facilitator Superfamily
AM609_RS13405	COG0237	dephospho-CoA kinase activity
AM609_RS13415	COG0385	Bile acid
AM609_RS13425	COG1780	Probably involved in ribonucleotide reductase function
AM609_RS13460	COG0366	Alpha amylase catalytic
AM609_RS13470	COG3550	peptidyl-serine autophosphorylation
AM609_RS13475	COG1760	l-serine dehydratase
AM609_RS13490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM609_RS13495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM609_RS13500	COG1113	amino acid transport
AM609_RS13515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM609_RS13515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM609_RS13740	COG0628	permease
AM609_RS13750	COG2197	response regulator
AM609_RS13770	COG1132	(ABC) transporter
AM609_RS13795	COG1136	(ABC) transporter
AM609_RS13795	COG0577	efflux transmembrane transporter activity
AM609_RS13800	COG1136	(ABC) transporter
AM609_RS13805	COG3177	Filamentation induced by cAMP protein fic
AM609_RS13815	COG2197	response regulator
AM609_RS13825	COG0170	dolichyl monophosphate biosynthetic process
AM609_RS13830	COG1136	(ABC) transporter
AM609_RS13830	COG0577	efflux transmembrane transporter activity
AM609_RS13835	COG2311	Membrane
AM609_RS13840	COG0577	efflux transmembrane transporter activity
AM609_RS13840	COG1136	(ABC) transporter
AM609_RS13845	COG1136	(ABC) transporter
AM609_RS13845	COG0577	efflux transmembrane transporter activity
AM609_RS13855	COG0477	Major facilitator Superfamily
AM609_RS13875	COG1131	(ABC) transporter
AM609_RS13890	COG0471	metal ion transport
AM609_RS13905	COG1854	S-ribosylhomocysteine lyase activity
AM609_RS13920	COG2267	carboxylic ester hydrolase activity
AM609_RS13930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM609_RS13960	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM609_RS13965	COG3293	Transposase
AM609_RS13980	COG1716	ATPase activity
AM609_RS13985	COG1716	ATPase activity
AM609_RS14000	COG0768	penicillin binding
AM609_RS14005	COG0515	serine threonine protein kinase
AM609_RS14020	COG3764	Sortase (surface protein transpeptidase)
AM609_RS14060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM609_RS14065	COG0187	DNA topoisomerase II activity
AM609_RS14075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM609_RS14080	COG0592	DNA-directed DNA polymerase activity
AM609_RS14085	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM609_RS14090	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM609_RS14095	COG0594	ribonuclease P activity
AM609_RS14100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM609_RS14105	COG0706	membrane insertase activity
AM609_RS14115	COG0357	Ribosomal RNA small subunit methyltransferase G
AM609_RS14120	COG1192	Involved in chromosome partitioning
AM609_RS14135	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM609_RS14140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM609_RS14145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM609_RS14150	COG0110	maltose O-acetyltransferase activity
AM609_RS14155	COG3118	belongs to the thioredoxin family
AM609_RS14160	COG0492	ferredoxin-NADP+ reductase activity
AM609_RS14190	COG0617	tRNA 3'-terminal CCA addition
AM609_RS14245	COG4152	abc transporter atp-binding protein
AM609_RS14250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM609_RS14265	COG2197	response regulator
AM609_RS14280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM609_RS14335	COG2211	Major facilitator Superfamily
AM609_RS14350	COG0789	Transcriptional regulator
AM609_RS14355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM609_RS14370	COG0360	Binds together with S18 to 16S ribosomal RNA
AM609_RS14380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM609_RS14385	COG0359	binds to the 23S rRNA
AM609_RS14400	COG2197	response regulator
AM609_RS14405	COG0534	Mate efflux family protein
AM609_RS14410	COG0305	Participates in initiation and elongation during chromosome replication
AM609_RS14425	COG0833	amino acid
AM609_RS14430	COG1834	amidinotransferase
AM609_RS14440	COG1121	(ABC) transporter
AM609_RS14460	COG0351	phosphomethylpyrimidine kinase
AM609_RS14470	COG1733	regulation of RNA biosynthetic process
AM609_RS14485	COG0515	serine threonine protein kinase
AM609_RS14490	COG0515	serine threonine protein kinase
AM609_RS14495	COG1716	ATPase activity
AM609_RS14495	COG0842	Transport permease protein
AM609_RS14495	COG1131	(ABC) transporter
AM609_RS14505	COG1404	Belongs to the peptidase S8 family
AM609_RS14510	COG0483	inositol monophosphate 1-phosphatase activity
AM609_RS14585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM609_RS14595	COG1464	Belongs to the NlpA lipoprotein family
AM609_RS14635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM609_RS14640	COG2197	response regulator
AM609_RS14655	COG0110	maltose O-acetyltransferase activity
AM609_RS14680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM609_RS14720	COG3328	transposase activity
AM609_RS14735	COG2233	PERMEase
AM609_RS14790	COG1643	Atp-dependent helicase
AM609_RS14800	COG0590	tRNA wobble adenosine to inosine editing
AM609_RS14800	COG0037	tRNA processing
AM609_RS14805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM609_RS14815	COG0577	efflux transmembrane transporter activity
AM609_RS14815	COG1136	(ABC) transporter
AM609_RS14840	COG1597	lipid kinase activity
AM609_RS14850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM609_RS14855	COG0561	phosphatase activity
AM609_RS14860	COG1653	transport
AM609_RS14895	COG0596	Alpha beta hydrolase
AM609_RS14905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM609_RS14935	COG0626	cystathionine gamma-synthase activity
AM609_RS14940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM609_RS14945	COG1132	(ABC) transporter
AM609_RS14950	COG1132	(ABC) transporter
AM609_RS14955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM609_RS14960	COG1397	ADP-ribosylglycohydrolase
AM609_RS14970	COG1132	(ABC) transporter
AM609_RS14970	COG2375	cellular response to nickel ion
AM609_RS14975	COG1132	(ABC) transporter
AM609_RS14990	COG3189	MarR family transcriptional regulator
AM609_RS14995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM609_RS15005	COG0546	phosphoglycolate phosphatase activity
AM609_RS15090	COG2197	response regulator
AM609_RS15095	COG4585	Histidine kinase
AM609_RS15100	COG2197	response regulator
AM609_RS15115	COG3548	integral membrane protein
AM609_RS15120	COG2181	nitrate reductase activity
AM609_RS15120	COG0247	lactate metabolic process
AM609_RS15135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM609_RS15140	COG0470	DNA polymerase III
AM609_RS15160	COG0252	asparaginase activity
AM609_RS15175	COG0588	phosphoglycerate mutase activity
AM609_RS15180	COG0704	Plays a role in the regulation of phosphate uptake
AM609_RS15185	COG5002	protein histidine kinase activity
AM609_RS15195	COG1329	Transcriptional regulator
AM609_RS15200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM609_RS15215	COG2409	Drug exporters of the RND superfamily