locus-tag	class	description
ACWT_RS00010	COG0592	DNA-directed DNA polymerase activity
ACWT_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACWT_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACWT_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ACWT_RS00040	COG0187	DNA topoisomerase II activity
ACWT_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACWT_RS00070	COG2197	response regulator
ACWT_RS00075	COG4585	Histidine kinase
ACWT_RS00105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACWT_RS00130	COG0326	Molecular chaperone. Has ATPase activity
ACWT_RS00145	COG0439	Biotin carboxylase
ACWT_RS00150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACWT_RS00170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACWT_RS00175	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS00185	COG1846	Transcriptional regulator
ACWT_RS00235	COG1716	ATPase activity
ACWT_RS00235	COG1716	ATPase activity
ACWT_RS00240	COG1716	ATPase activity
ACWT_RS00255	COG0768	penicillin binding
ACWT_RS00260	COG0515	serine threonine protein kinase
ACWT_RS00265	COG2815	serine threonine protein kinase
ACWT_RS00265	COG0515	serine threonine protein kinase
ACWT_RS00295	COG2181	nitrate reductase activity
ACWT_RS00295	COG0247	lactate metabolic process
ACWT_RS00325	COG0717	Belongs to the dCTP deaminase family
ACWT_RS00340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACWT_RS00345	COG2208	phosphoserine phosphatase activity
ACWT_RS00345	COG2770	Histidine kinase
ACWT_RS00350	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS00395	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACWT_RS00400	COG0022	dehydrogenase e1 component
ACWT_RS00430	COG0443	Heat shock 70 kDa protein
ACWT_RS00435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACWT_RS00440	COG0484	heat shock protein binding
ACWT_RS00445	COG0789	Transcriptional regulator
ACWT_RS00455	COG0475	glutathione-regulated potassium exporter activity
ACWT_RS00465	COG2814	Major facilitator Superfamily
ACWT_RS00470	COG0542	response to heat
ACWT_RS00500	COG0640	Transcriptional regulator
ACWT_RS00510	COG0586	Pfam SNARE associated Golgi protein
ACWT_RS00515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACWT_RS00570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACWT_RS00575	COG0151	Belongs to the GarS family
ACWT_RS00590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACWT_RS00595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACWT_RS00600	COG0047	phosphoribosylformylglycinamidine synthase activity
ACWT_RS00605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACWT_RS00625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACWT_RS00630	COG0641	radical SAM
ACWT_RS00665	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
ACWT_RS00720	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ACWT_RS00730	COG0142	geranyltranstransferase activity
ACWT_RS00745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACWT_RS00775	COG0515	serine threonine protein kinase
ACWT_RS00780	COG1595	DNA-templated transcription, initiation
ACWT_RS00800	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACWT_RS00805	COG1121	(ABC) transporter
ACWT_RS00810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACWT_RS00820	COG0640	Transcriptional regulator
ACWT_RS00825	COG0701	Predicted permease
ACWT_RS00840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACWT_RS00870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACWT_RS00980	COG1971	Probably functions as a manganese efflux pump
ACWT_RS01010	COG5002	protein histidine kinase activity
ACWT_RS01045	COG1902	pentaerythritol trinitrate reductase activity
ACWT_RS01105	COG1131	(ABC) transporter
ACWT_RS01115	COG0671	phosphoesterase, PA-phosphatase related
ACWT_RS01120	COG0745	RESPONSE REGULATOR receiver
ACWT_RS01125	COG2205	protein histidine kinase activity
ACWT_RS01150	COG0739	heme binding
ACWT_RS01150	COG0741	lytic transglycosylase activity
ACWT_RS01150	COG1196	nuclear chromosome segregation
ACWT_RS01165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACWT_RS01240	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS01255	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACWT_RS01280	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS01285	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS01285	COG2172	sigma factor antagonist activity
ACWT_RS01285	COG2208	phosphoserine phosphatase activity
ACWT_RS01295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS01300	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACWT_RS01340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACWT_RS01355	COG1136	(ABC) transporter
ACWT_RS01375	COG0745	RESPONSE REGULATOR receiver
ACWT_RS01380	COG2205	protein histidine kinase activity
ACWT_RS01380	COG0784	Response regulator, receiver
ACWT_RS01390	COG2172	sigma factor antagonist activity
ACWT_RS01395	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS01400	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS01410	COG1970	mechanosensitive ion channel activity
ACWT_RS01455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACWT_RS01460	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACWT_RS01470	COG0784	Response regulator, receiver
ACWT_RS01470	COG2205	protein histidine kinase activity
ACWT_RS01475	COG0745	RESPONSE REGULATOR receiver
ACWT_RS01495	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS01500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACWT_RS01505	COG0406	alpha-ribazole phosphatase activity
ACWT_RS01510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACWT_RS01515	COG0785	Cytochrome C biogenesis protein
ACWT_RS01525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACWT_RS01535	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACWT_RS01545	COG0163	prenyltransferase activity
ACWT_RS01570	COG0513	Belongs to the DEAD box helicase family
ACWT_RS01590	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACWT_RS01605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACWT_RS01610	COG1120	ATPase activity
ACWT_RS01640	COG3973	AAA domain
ACWT_RS01655	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACWT_RS01660	COG0667	Aldo Keto reductase
ACWT_RS01665	COG4279	zinc finger
ACWT_RS01670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACWT_RS01685	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACWT_RS01690	COG2226	methyltransferase
ACWT_RS01710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS01715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS01720	COG0649	NAD binding
ACWT_RS01735	COG1034	ATP synthesis coupled electron transport
ACWT_RS01740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACWT_RS01745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS01750	COG0839	Belongs to the complex I subunit 6 family
ACWT_RS01755	COG0713	ATP synthesis coupled electron transport
ACWT_RS01770	COG1007	ATP synthesis coupled electron transport
ACWT_RS01775	COG0142	geranyltranstransferase activity
ACWT_RS01795	COG1950	PFAM Membrane protein of
ACWT_RS01830	COG0596	Alpha beta hydrolase
ACWT_RS01845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACWT_RS01905	COG1111	helicase
ACWT_RS01905	COG1205	dead DEAH box helicase
ACWT_RS01910	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS01920	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACWT_RS01935	COG1754	DNA topoisomerase type I activity
ACWT_RS01935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACWT_RS01945	COG1309	transcriptional regulator
ACWT_RS01955	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACWT_RS01965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACWT_RS01995	COG1774	PSP1 C-terminal conserved region
ACWT_RS02025	COG1404	Belongs to the peptidase S8 family
ACWT_RS02040	COG0738	Major facilitator superfamily
ACWT_RS02085	COG3285	dna ligase
ACWT_RS02085	COG1793	dna ligase
ACWT_RS02095	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ACWT_RS02125	COG1061	Type III restriction enzyme res subunit
ACWT_RS02140	COG1278	Cold shock
ACWT_RS02145	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACWT_RS02175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACWT_RS02180	COG2814	Major facilitator Superfamily
ACWT_RS02190	COG2814	Major facilitator Superfamily
ACWT_RS02205	COG2252	PERMEase
ACWT_RS02210	COG1846	Transcriptional regulator
ACWT_RS02215	COG2814	Major facilitator Superfamily
ACWT_RS02225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ACWT_RS02235	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACWT_RS02245	COG0259	pyridoxamine-phosphate oxidase activity
ACWT_RS02255	COG2017	converts alpha-aldose to the beta-anomer
ACWT_RS02285	COG3842	ATPase activity
ACWT_RS02315	COG1134	teichoic acid transport
ACWT_RS02315	COG1388	LysM domain
ACWT_RS02325	COG1309	transcriptional regulator
ACWT_RS02350	COG0477	Major facilitator Superfamily
ACWT_RS02395	COG0745	RESPONSE REGULATOR receiver
ACWT_RS02400	COG0604	alcohol dehydrogenase
ACWT_RS02405	COG3850	Histidine kinase
ACWT_RS02410	COG2197	response regulator
ACWT_RS02420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACWT_RS02425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACWT_RS02430	COG3300	MHYT domain
ACWT_RS02430	COG5001	Diguanylate cyclase
ACWT_RS02440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACWT_RS02460	COG0596	Alpha beta hydrolase
ACWT_RS02465	COG2119	membrane
ACWT_RS02485	COG0477	Major facilitator Superfamily
ACWT_RS02520	COG0586	Pfam SNARE associated Golgi protein
ACWT_RS02550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACWT_RS02590	COG1309	transcriptional regulator
ACWT_RS02595	COG1131	(ABC) transporter
ACWT_RS02600	COG3559	Exporter of polyketide antibiotics
ACWT_RS02615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACWT_RS02630	COG3795	YCII-related domain
ACWT_RS02635	COG4941	Belongs to the sigma-70 factor family
ACWT_RS02655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACWT_RS02660	COG2271	Major facilitator Superfamily
ACWT_RS02700	COG2971	BadF BadG BcrA BcrD
ACWT_RS02705	COG1737	Transcriptional regulator
ACWT_RS02710	COG4821	SIS domain
ACWT_RS02750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACWT_RS02765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACWT_RS02770	COG2188	Transcriptional regulator
ACWT_RS02780	COG1595	DNA-templated transcription, initiation
ACWT_RS02865	COG2409	Drug exporters of the RND superfamily
ACWT_RS02875	COG0657	acetylesterase activity
ACWT_RS02890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACWT_RS02890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACWT_RS02895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACWT_RS02900	COG2203	Gaf domain
ACWT_RS02900	COG2199	diguanylate cyclase activity
ACWT_RS02900	COG2200	EAL domain
ACWT_RS02905	COG3469	chitinase activity
ACWT_RS02920	COG0583	DNA-binding transcription factor activity
ACWT_RS02930	COG1388	LysM domain
ACWT_RS02935	COG3268	Saccharopine dehydrogenase
ACWT_RS02940	COG0275	rRNA processing
ACWT_RS02970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACWT_RS02975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACWT_RS02980	COG2205	protein histidine kinase activity
ACWT_RS02985	COG0745	RESPONSE REGULATOR receiver
ACWT_RS03010	COG2201	protein-glutamate methylesterase activity
ACWT_RS03015	COG4251	negative regulation of phosphorylation
ACWT_RS03020	COG0784	Response regulator, receiver
ACWT_RS03025	COG0483	inositol monophosphate 1-phosphatase activity
ACWT_RS03040	COG0515	serine threonine protein kinase
ACWT_RS03040	COG2815	serine threonine protein kinase
ACWT_RS03055	COG0514	ATP-dependent DNA helicase (RecQ)
ACWT_RS03070	COG1937	Protein conserved in bacteria
ACWT_RS03095	COG0513	Belongs to the DEAD box helicase family
ACWT_RS03145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACWT_RS03150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACWT_RS03160	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACWT_RS03190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS03210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS03215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACWT_RS03220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS03225	COG0839	Belongs to the complex I subunit 6 family
ACWT_RS03230	COG0713	ATP synthesis coupled electron transport
ACWT_RS03235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACWT_RS03240	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS03245	COG1007	ATP synthesis coupled electron transport
ACWT_RS03250	COG0501	Belongs to the peptidase M48B family
ACWT_RS03260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS03295	COG1666	GTP binding
ACWT_RS03305	COG1280	lysine exporter protein (LysE YggA)
ACWT_RS03320	COG3300	MHYT domain
ACWT_RS03320	COG5001	Diguanylate cyclase
ACWT_RS03335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACWT_RS03340	COG2030	dehydratase
ACWT_RS03365	COG0081	regulation of translation
ACWT_RS03380	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACWT_RS03385	COG0222	ribosome binding
ACWT_RS03390	COG0085	RNA polymerase activity
ACWT_RS03395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACWT_RS03410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACWT_RS03415	COG0049	tRNA binding
ACWT_RS03420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACWT_RS03425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACWT_RS03430	COG0051	transcription antitermination factor activity, RNA binding
ACWT_RS03435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACWT_RS03440	COG0088	Forms part of the polypeptide exit tunnel
ACWT_RS03445	COG0089	rRNA binding
ACWT_RS03450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACWT_RS03455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACWT_RS03460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACWT_RS03465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACWT_RS03470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACWT_RS03475	COG0255	Belongs to the universal ribosomal protein uL29 family
ACWT_RS03480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACWT_RS03485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACWT_RS03490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACWT_RS03495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACWT_RS03500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACWT_RS03505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACWT_RS03510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACWT_RS03515	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACWT_RS03520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACWT_RS03525	COG1841	ribosomal large subunit assembly
ACWT_RS03530	COG0200	Binds to the 23S rRNA
ACWT_RS03540	COG0563	adenylate kinase activity
ACWT_RS03555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACWT_RS03560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACWT_RS03565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACWT_RS03570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACWT_RS03575	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACWT_RS03585	COG0203	ribosomal protein L17
ACWT_RS03590	COG0101	tRNA pseudouridine synthase activity
ACWT_RS03600	COG2813	Specifically methylates the guanine in position
ACWT_RS03605	COG0488	(ABC) transporter
ACWT_RS03610	COG0352	thiamine-phosphate diphosphorylase activity
ACWT_RS03615	COG2022	thiamine diphosphate biosynthetic process
ACWT_RS03615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACWT_RS03625	COG2022	thiamine diphosphate biosynthetic process
ACWT_RS03630	COG0352	thiamine-phosphate diphosphorylase activity
ACWT_RS03635	COG0351	phosphomethylpyrimidine kinase
ACWT_RS03640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACWT_RS03670	COG2018	Roadblock/LC7 domain
ACWT_RS03690	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACWT_RS03695	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACWT_RS03700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACWT_RS03715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACWT_RS03730	COG0736	holo-[acyl-carrier-protein] synthase activity
ACWT_RS03740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACWT_RS03750	COG0802	atpase or kinase
ACWT_RS03755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACWT_RS03770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACWT_RS03780	COG1132	(ABC) transporter
ACWT_RS03790	COG0459	protein refolding
ACWT_RS03795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACWT_RS03805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACWT_RS03810	COG4213	ABC transporter substrate-binding protein
ACWT_RS03820	COG4214	carbohydrate transport
ACWT_RS03855	COG2197	response regulator
ACWT_RS03870	COG0516	GMP reductase activity
ACWT_RS03880	COG1316	TRANSCRIPTIONal
ACWT_RS03885	COG0519	Catalyzes the synthesis of GMP from XMP
ACWT_RS03885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACWT_RS03890	COG1051	belongs to the nudix hydrolase family
ACWT_RS03895	COG0494	nUDIX hydrolase
ACWT_RS03900	COG1183	phosphatidylcholine synthase activity
ACWT_RS03905	COG0688	phosphatidylethanolamine metabolic process
ACWT_RS03920	COG4585	Histidine kinase
ACWT_RS03925	COG2197	response regulator
ACWT_RS03930	COG4166	transmembrane transport
ACWT_RS03935	COG0601	transmembrane transport
ACWT_RS03940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACWT_RS03945	COG0444	Belongs to the ABC transporter superfamily
ACWT_RS03950	COG4608	Belongs to the ABC transporter superfamily
ACWT_RS03955	COG1605	Chorismate mutase
ACWT_RS03960	COG4085	toxin activity
ACWT_RS03960	COG1525	nuclease
ACWT_RS03960	COG0737	Belongs to the 5'-nucleotidase family
ACWT_RS03970	COG0739	heme binding
ACWT_RS03980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACWT_RS03985	COG0045	succinate-CoA ligase (ADP-forming) activity
ACWT_RS04005	COG0138	bifunctional purine biosynthesis protein purh
ACWT_RS04020	COG0538	isocitrate dehydrogenase activity
ACWT_RS04035	COG1349	DNA-binding transcription factor activity
ACWT_RS04055	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ACWT_RS04100	COG3206	protein involved in exopolysaccharide biosynthesis
ACWT_RS04100	COG0489	protein tyrosine kinase activity
ACWT_RS04105	COG0529	Catalyzes the synthesis of activated sulfate
ACWT_RS04125	COG1131	(ABC) transporter
ACWT_RS04135	COG0640	Transcriptional regulator
ACWT_RS04140	COG0604	alcohol dehydrogenase
ACWT_RS04145	COG0604	alcohol dehydrogenase
ACWT_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS04145	COG3321	synthase
ACWT_RS04160	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACWT_RS04165	COG1024	Enoyl-CoA hydratase
ACWT_RS04165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACWT_RS04200	COG0148	phosphopyruvate hydratase activity
ACWT_RS04215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACWT_RS04245	COG0714	Associated with various cellular activities
ACWT_RS04280	COG0183	Belongs to the thiolase family
ACWT_RS04305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACWT_RS04315	COG0456	acetyltransferase
ACWT_RS04320	COG1234	tRNA 3'-trailer cleavage
ACWT_RS04325	COG2326	polyphosphate kinase activity
ACWT_RS04345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACWT_RS04365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACWT_RS04370	COG0501	Belongs to the peptidase M48B family
ACWT_RS04375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACWT_RS04385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACWT_RS04405	COG1331	Highly conserved protein containing a thioredoxin domain
ACWT_RS04415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACWT_RS04460	COG5001	Diguanylate cyclase
ACWT_RS04480	COG0577	efflux transmembrane transporter activity
ACWT_RS04480	COG1136	(ABC) transporter
ACWT_RS04490	COG3629	intracellular signal transduction
ACWT_RS04490	COG3903	Transcriptional regulator
ACWT_RS04505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACWT_RS04525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACWT_RS04530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACWT_RS04535	COG2423	ornithine cyclodeaminase activity
ACWT_RS04565	COG1132	(ABC) transporter
ACWT_RS04690	COG1609	Transcriptional regulator
ACWT_RS04705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACWT_RS04725	COG1607	acyl-coa hydrolase
ACWT_RS04735	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS04755	COG0778	Nitroreductase
ACWT_RS04755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ACWT_RS04760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACWT_RS04770	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACWT_RS04805	COG1012	belongs to the aldehyde dehydrogenase family
ACWT_RS04815	COG1515	deoxyribonuclease V activity
ACWT_RS04820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACWT_RS04825	COG2835	tetraacyldisaccharide 4'-kinase activity
ACWT_RS04855	COG0745	RESPONSE REGULATOR receiver
ACWT_RS04860	COG5002	protein histidine kinase activity
ACWT_RS04875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACWT_RS04885	COG0653	protein targeting
ACWT_RS04915	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACWT_RS04920	COG2884	Cell division ATP-binding protein ftsE
ACWT_RS04925	COG2177	Part of the ABC transporter FtsEX involved in
ACWT_RS04930	COG0739	heme binding
ACWT_RS04930	COG0741	lytic transglycosylase activity
ACWT_RS04930	COG1196	nuclear chromosome segregation
ACWT_RS04935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACWT_RS05005	COG2188	Transcriptional regulator
ACWT_RS05095	COG1595	DNA-templated transcription, initiation
ACWT_RS05105	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACWT_RS05110	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACWT_RS05130	COG1678	Uncharacterized ACR, COG1678
ACWT_RS05135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACWT_RS05145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS05165	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACWT_RS05175	COG1459	type II secretion system
ACWT_RS05185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACWT_RS05290	COG5002	protein histidine kinase activity
ACWT_RS05290	COG5001	Diguanylate cyclase
ACWT_RS05305	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ACWT_RS05310	COG3285	dna ligase
ACWT_RS05310	COG1793	dna ligase
ACWT_RS05315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACWT_RS05320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACWT_RS05335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS05345	COG1335	isochorismatase
ACWT_RS05350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACWT_RS05385	COG1234	tRNA 3'-trailer cleavage
ACWT_RS05390	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS05395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACWT_RS05400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACWT_RS05405	COG2986	histidine ammonia-lyase
ACWT_RS05410	COG1228	amidohydrolase
ACWT_RS05415	COG0402	S-adenosylhomocysteine deaminase activity
ACWT_RS05420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACWT_RS05425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACWT_RS05455	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACWT_RS05495	COG1276	copper resistance
ACWT_RS05495	COG2372	response to copper ion
ACWT_RS05505	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACWT_RS05550	COG3226	Transcriptional regulator
ACWT_RS05565	COG1376	ErfK ybiS ycfS ynhG family protein
ACWT_RS05570	COG1376	ErfK ybiS ycfS ynhG family protein
ACWT_RS05590	COG4733	cellulase activity
ACWT_RS05600	COG2197	response regulator
ACWT_RS05615	COG2124	cytochrome p450
ACWT_RS05640	COG5001	Diguanylate cyclase
ACWT_RS05640	COG5002	protein histidine kinase activity
ACWT_RS05735	COG0277	FAD linked oxidase domain protein
ACWT_RS05745	COG0745	RESPONSE REGULATOR receiver
ACWT_RS05770	COG0598	Magnesium transport protein CorA
ACWT_RS05830	COG1609	Transcriptional regulator
ACWT_RS05835	COG2706	6-phosphogluconolactonase activity
ACWT_RS05850	COG2115	Belongs to the xylose isomerase family
ACWT_RS05855	COG1070	Carbohydrate kinase
ACWT_RS05865	COG0366	Alpha amylase catalytic
ACWT_RS05870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACWT_RS05895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACWT_RS05970	COG2197	response regulator
ACWT_RS05990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACWT_RS06040	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACWT_RS06045	COG1492	cobalamin metabolic process
ACWT_RS06050	COG0501	Belongs to the peptidase M48B family
ACWT_RS06070	COG1793	dna ligase
ACWT_RS06105	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACWT_RS06110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACWT_RS06110	COG1648	precorrin-2 dehydrogenase activity
ACWT_RS06115	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACWT_RS06160	COG0668	transmembrane transport
ACWT_RS06185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACWT_RS06200	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACWT_RS06220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACWT_RS06230	COG4552	Acetyltransferase involved in intracellular survival and related
ACWT_RS06250	COG0640	Transcriptional regulator
ACWT_RS06270	COG1595	DNA-templated transcription, initiation
ACWT_RS06275	COG0640	Transcriptional regulator
ACWT_RS06280	COG2814	Major facilitator Superfamily
ACWT_RS06305	COG1063	alcohol dehydrogenase
ACWT_RS06325	COG0494	nUDIX hydrolase
ACWT_RS06340	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACWT_RS06345	COG0740	serine-type endopeptidase activity
ACWT_RS06350	COG0740	serine-type endopeptidase activity
ACWT_RS06355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACWT_RS06395	COG0525	valine-tRNA ligase activity
ACWT_RS06400	COG0285	dihydrofolate synthase activity
ACWT_RS06415	COG0105	UTP biosynthetic process
ACWT_RS06420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACWT_RS06435	COG0596	Alpha beta hydrolase
ACWT_RS06440	COG2208	phosphoserine phosphatase activity
ACWT_RS06440	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS06440	COG2172	sigma factor antagonist activity
ACWT_RS06460	COG1530	ribonuclease E activity
ACWT_RS06470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACWT_RS06475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACWT_RS06480	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACWT_RS06490	COG0180	Tryptophanyl-tRNA synthetase
ACWT_RS06505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACWT_RS06515	COG0406	alpha-ribazole phosphatase activity
ACWT_RS06525	COG1307	EDD domain protein, DegV family
ACWT_RS06535	COG2890	protein-(glutamine-N5) methyltransferase activity
ACWT_RS06540	COG1555	photosystem II stabilization
ACWT_RS06540	COG1596	polysaccharide export
ACWT_RS06545	COG0658	competence protein
ACWT_RS06545	COG2333	competence protein COMEC
ACWT_RS06560	COG0268	Binds directly to 16S ribosomal RNA
ACWT_RS06585	COG0481	GTPase activity
ACWT_RS06590	COG2261	transglycosylase associated protein
ACWT_RS06620	COG1420	regulation of RNA biosynthetic process
ACWT_RS06625	COG0484	heat shock protein binding
ACWT_RS06640	COG1695	Transcriptional regulator
ACWT_RS06655	COG0537	adenosine 5'-monophosphoramidase activity
ACWT_RS06670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACWT_RS06685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACWT_RS06700	COG1381	Involved in DNA repair and RecF pathway recombination
ACWT_RS06705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACWT_RS06740	COG1122	ATPase activity
ACWT_RS06750	COG2267	carboxylic ester hydrolase activity
ACWT_RS06775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACWT_RS06780	COG1121	(ABC) transporter
ACWT_RS06785	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACWT_RS06805	COG0423	glycine-tRNA ligase activity
ACWT_RS06815	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACWT_RS06815	COG3608	succinylglutamate desuccinylase aspartoacylase
ACWT_RS06835	COG2018	Roadblock/LC7 domain
ACWT_RS06860	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACWT_RS06875	COG1131	(ABC) transporter
ACWT_RS06890	COG1295	ribonuclease BN
ACWT_RS06940	COG4115	mRNA cleavage
ACWT_RS06945	COG2161	toxin-antitoxin pair type II binding
ACWT_RS06990	COG3469	chitinase activity
ACWT_RS07000	COG3250	beta-galactosidase activity
ACWT_RS07060	COG2746	aminoglycoside 3-N-acetyltransferase activity
ACWT_RS07070	COG0641	radical SAM
ACWT_RS07080	COG3903	Transcriptional regulator
ACWT_RS07080	COG3629	intracellular signal transduction
ACWT_RS07090	COG3903	Transcriptional regulator
ACWT_RS07090	COG3629	intracellular signal transduction
ACWT_RS07115	COG0018	arginyl-trna synthetase
ACWT_RS07120	COG0737	Belongs to the 5'-nucleotidase family
ACWT_RS07135	COG0515	serine threonine protein kinase
ACWT_RS07155	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACWT_RS07170	COG3973	AAA domain
ACWT_RS07195	COG1472	Belongs to the glycosyl hydrolase 3 family
ACWT_RS07210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACWT_RS07215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACWT_RS07245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACWT_RS07250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACWT_RS07255	COG0432	Pfam Uncharacterised protein family UPF0047
ACWT_RS07315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACWT_RS07360	COG0730	response to heat
ACWT_RS07370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACWT_RS07375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACWT_RS07390	COG2226	methyltransferase
ACWT_RS07420	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ACWT_RS07425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACWT_RS07430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACWT_RS07430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACWT_RS07435	COG0174	glutamine synthetase
ACWT_RS07440	COG3766	membrane
ACWT_RS07450	COG2378	regulation of single-species biofilm formation
ACWT_RS07465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACWT_RS07470	COG1846	Transcriptional regulator
ACWT_RS07485	COG1051	belongs to the nudix hydrolase family
ACWT_RS07550	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS07620	COG1674	ftsk spoiiie
ACWT_RS07660	COG2197	response regulator
ACWT_RS07670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACWT_RS07675	COG0017	Asparaginyl-tRNA synthetase
ACWT_RS07685	COG0321	lipoyl(octanoyl) transferase activity
ACWT_RS07700	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACWT_RS07705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACWT_RS07715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACWT_RS07720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACWT_RS07730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ACWT_RS07735	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACWT_RS07745	COG1994	Peptidase M50
ACWT_RS07750	COG0667	Aldo Keto reductase
ACWT_RS07780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACWT_RS07795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACWT_RS07800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACWT_RS07805	COG1929	Belongs to the glycerate kinase type-1 family
ACWT_RS07815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACWT_RS07825	COG0425	Belongs to the sulfur carrier protein TusA family
ACWT_RS07830	COG1104	cysteine desulfurase activity
ACWT_RS07835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACWT_RS07850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACWT_RS07905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACWT_RS07915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACWT_RS07935	COG0501	Belongs to the peptidase M48B family
ACWT_RS07940	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS07955	COG1132	(ABC) transporter
ACWT_RS07980	COG2197	response regulator
ACWT_RS08000	COG1940	carbohydrate kinase activity
ACWT_RS08030	COG0204	Acyl-transferase
ACWT_RS08060	COG0205	6-phosphofructokinase activity
ACWT_RS08110	COG0386	Belongs to the glutathione peroxidase family
ACWT_RS08120	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACWT_RS08140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACWT_RS08145	COG2815	serine threonine protein kinase
ACWT_RS08145	COG0515	serine threonine protein kinase
ACWT_RS08165	COG0142	geranyltranstransferase activity
ACWT_RS08220	COG1309	transcriptional regulator
ACWT_RS08230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACWT_RS08235	COG1053	succinate dehydrogenase
ACWT_RS08245	COG0583	DNA-binding transcription factor activity
ACWT_RS08325	COG0587	DNA-directed DNA polymerase activity
ACWT_RS08365	COG0714	Associated with various cellular activities
ACWT_RS08370	COG0495	leucyl-tRNA aminoacylation
ACWT_RS08380	COG3442	glutamine amidotransferase
ACWT_RS08385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACWT_RS08395	COG2001	Belongs to the MraZ family
ACWT_RS08400	COG0275	rRNA processing
ACWT_RS08410	COG0768	penicillin binding
ACWT_RS08415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACWT_RS08425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACWT_RS08435	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACWT_RS08440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACWT_RS08450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACWT_RS08460	COG1799	cell septum assembly
ACWT_RS08470	COG3599	regulation of cell shape
ACWT_RS08490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACWT_RS08510	COG0587	DNA-directed DNA polymerase activity
ACWT_RS08520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACWT_RS08525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACWT_RS08530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACWT_RS08535	COG0131	Imidazoleglycerol-phosphate dehydratase
ACWT_RS08550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACWT_RS08555	COG0107	imidazoleglycerol-phosphate synthase activity
ACWT_RS08570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACWT_RS08580	COG1022	Amp-dependent synthetase and ligase
ACWT_RS08585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACWT_RS08605	COG1132	(ABC) transporter
ACWT_RS08610	COG1132	(ABC) transporter
ACWT_RS08615	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACWT_RS08630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACWT_RS08660	COG0159	tryptophan synthase activity
ACWT_RS08670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACWT_RS08675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACWT_RS08685	COG0069	glutamate synthase activity
ACWT_RS08685	COG0067	glutamate synthase
ACWT_RS08685	COG0070	glutamate synthase
ACWT_RS08750	COG0765	amino acid transport
ACWT_RS08780	COG2226	methyltransferase
ACWT_RS08785	COG0539	negative regulation of cytoplasmic translation
ACWT_RS08790	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACWT_RS08790	COG0237	dephospho-CoA kinase activity
ACWT_RS08805	COG2329	Antibiotic biosynthesis monooxygenase
ACWT_RS08815	COG1217	gtp-binding protein TYPA
ACWT_RS08825	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACWT_RS08830	COG0740	serine-type endopeptidase activity
ACWT_RS08845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACWT_RS08855	COG1162	GTPase activity
ACWT_RS08865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACWT_RS08875	COG0322	excinuclease ABC activity
ACWT_RS08880	COG1660	Displays ATPase and GTPase activities
ACWT_RS08890	COG1481	regulation of sporulation
ACWT_RS08895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACWT_RS08900	COG0126	phosphoglycerate kinase activity
ACWT_RS08905	COG0149	triose-phosphate isomerase activity
ACWT_RS08910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACWT_RS08930	COG0363	glucosamine-6-phosphate deaminase activity
ACWT_RS08945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACWT_RS08950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACWT_RS08955	COG0109	protoheme IX farnesyltransferase activity
ACWT_RS08995	COG0396	ATPase activity
ACWT_RS09000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACWT_RS09005	COG0822	iron-sulfur transferase activity
ACWT_RS09040	COG0588	phosphoglycerate mutase activity
ACWT_RS09060	COG2321	neutral zinc metallopeptidase
ACWT_RS09065	COG0488	(ABC) transporter
ACWT_RS09075	COG1024	Enoyl-CoA hydratase
ACWT_RS09080	COG1132	(ABC) transporter
ACWT_RS09085	COG3663	DNA glycosylase
ACWT_RS09105	COG1309	transcriptional regulator
ACWT_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS09135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACWT_RS09150	COG0006	proline dipeptidase activity
ACWT_RS09185	COG0714	Associated with various cellular activities
ACWT_RS09200	COG2197	response regulator
ACWT_RS09205	COG4585	Histidine kinase
ACWT_RS09215	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACWT_RS09220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACWT_RS09315	COG1365	unkown
ACWT_RS09320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACWT_RS09330	COG2182	Extracellular solute-binding protein
ACWT_RS09335	COG1175	transmembrane transport
ACWT_RS09340	COG0395	ABC-type sugar transport system, permease component
ACWT_RS09345	COG1653	transport
ACWT_RS09350	COG1175	transmembrane transport
ACWT_RS09355	COG0395	ABC-type sugar transport system, permease component
ACWT_RS09360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACWT_RS09360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACWT_RS09370	COG3265	gluconokinase activity
ACWT_RS09395	COG4585	Histidine kinase
ACWT_RS09400	COG2197	response regulator
ACWT_RS09475	COG3304	Inner membrane component domain
ACWT_RS09505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACWT_RS09510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACWT_RS09520	COG1309	transcriptional regulator
ACWT_RS09535	COG1309	transcriptional regulator
ACWT_RS09540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACWT_RS09555	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS09565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACWT_RS09570	COG2815	serine threonine protein kinase
ACWT_RS09570	COG0515	serine threonine protein kinase
ACWT_RS09585	COG5634	Uncharacterized conserved protein (DUF2278)
ACWT_RS09610	COG1253	flavin adenine dinucleotide binding
ACWT_RS09620	COG0840	transmembrane signaling receptor activity
ACWT_RS09645	COG3706	GGDEF domain
ACWT_RS09685	COG1175	transmembrane transport
ACWT_RS09700	COG2205	protein histidine kinase activity
ACWT_RS09705	COG0784	Response regulator, receiver
ACWT_RS09705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACWT_RS09705	COG2198	Histidine kinase
ACWT_RS09705	COG2205	protein histidine kinase activity
ACWT_RS09725	COG2205	protein histidine kinase activity
ACWT_RS09745	COG3850	Histidine kinase
ACWT_RS09745	COG5002	protein histidine kinase activity
ACWT_RS09755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACWT_RS09765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACWT_RS09770	COG3387	PFAM Glycoside hydrolase 15-related
ACWT_RS09775	COG1525	nuclease
ACWT_RS09780	COG0667	Aldo Keto reductase
ACWT_RS09810	COG2192	nodulation
ACWT_RS09825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACWT_RS09845	COG1129	ABC transporter
ACWT_RS09855	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS09880	COG1316	TRANSCRIPTIONal
ACWT_RS09885	COG0463	Glycosyl transferase, family 2
ACWT_RS09885	COG1216	Glycosyl transferase, family 2
ACWT_RS09945	COG1378	Sugar-specific transcriptional regulator TrmB
ACWT_RS09985	COG2070	2-Nitropropane dioxygenase
ACWT_RS10015	COG0436	Aminotransferase
ACWT_RS10045	COG0667	Aldo Keto reductase
ACWT_RS10060	COG0657	acetylesterase activity
ACWT_RS10175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACWT_RS10190	COG2203	Gaf domain
ACWT_RS10190	COG2199	diguanylate cyclase activity
ACWT_RS10200	COG0739	heme binding
ACWT_RS10200	COG1196	nuclear chromosome segregation
ACWT_RS10200	COG0741	lytic transglycosylase activity
ACWT_RS10205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACWT_RS10215	COG0789	Transcriptional regulator
ACWT_RS10225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACWT_RS10240	COG0243	molybdopterin cofactor binding
ACWT_RS10245	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACWT_RS10270	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS10290	COG0439	Biotin carboxylase
ACWT_RS10320	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACWT_RS10325	COG1070	Carbohydrate kinase
ACWT_RS10330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACWT_RS10360	COG2193	ferroxidase activity
ACWT_RS10370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACWT_RS10395	COG0395	ABC-type sugar transport system, permease component
ACWT_RS10400	COG1486	melibiose metabolic process
ACWT_RS10430	COG3537	Alpha-1,2-mannosidase
ACWT_RS10500	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS10505	COG1063	alcohol dehydrogenase
ACWT_RS10510	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACWT_RS10515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACWT_RS10525	COG2814	Major facilitator Superfamily
ACWT_RS10560	COG2175	clavaminate synthase activity
ACWT_RS10600	COG0840	transmembrane signaling receptor activity
ACWT_RS10605	COG2814	Major facilitator Superfamily
ACWT_RS10620	COG2197	response regulator
ACWT_RS10625	COG4585	Histidine kinase
ACWT_RS10655	COG0745	RESPONSE REGULATOR receiver
ACWT_RS10755	COG0464	growth
ACWT_RS10770	COG0714	Associated with various cellular activities
ACWT_RS10850	COG0642	Histidine kinase
ACWT_RS10905	COG2172	sigma factor antagonist activity
ACWT_RS10905	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS10905	COG2208	phosphoserine phosphatase activity
ACWT_RS10965	COG0714	Associated with various cellular activities
ACWT_RS11005	COG2205	protein histidine kinase activity
ACWT_RS11010	COG0784	Response regulator, receiver
ACWT_RS11010	COG2198	Histidine kinase
ACWT_RS11010	COG5002	protein histidine kinase activity
ACWT_RS11020	COG2226	methyltransferase
ACWT_RS11025	COG2814	Major facilitator Superfamily
ACWT_RS11045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACWT_RS11050	COG3537	Alpha-1,2-mannosidase
ACWT_RS11070	COG0789	Transcriptional regulator
ACWT_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS11170	COG1609	Transcriptional regulator
ACWT_RS11185	COG0477	Major facilitator Superfamily
ACWT_RS11195	COG3347	Dehydrogenase
ACWT_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS11200	COG1070	Carbohydrate kinase
ACWT_RS11205	COG0247	lactate metabolic process
ACWT_RS11210	COG1139	Iron-sulfur cluster binding protein
ACWT_RS11215	COG1556	Lactate utilization protein
ACWT_RS11225	COG0745	RESPONSE REGULATOR receiver
ACWT_RS11230	COG3852	Histidine kinase
ACWT_RS11245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACWT_RS11250	COG0577	efflux transmembrane transporter activity
ACWT_RS11250	COG1136	(ABC) transporter
ACWT_RS11255	COG1136	(ABC) transporter
ACWT_RS11255	COG0577	efflux transmembrane transporter activity
ACWT_RS11275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACWT_RS11290	COG4948	Mandelate Racemase Muconate Lactonizing
ACWT_RS11305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACWT_RS11385	COG0596	Alpha beta hydrolase
ACWT_RS11390	COG1116	anion transmembrane transporter activity
ACWT_RS11395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACWT_RS11400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACWT_RS11410	COG1414	Transcriptional regulator
ACWT_RS11425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACWT_RS11430	COG3706	GGDEF domain
ACWT_RS11460	COG1414	Transcriptional regulator
ACWT_RS11465	COG3485	protocatechuate 3,4-dioxygenase
ACWT_RS11470	COG3485	protocatechuate 3,4-dioxygenase
ACWT_RS11480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACWT_RS11515	COG2197	response regulator
ACWT_RS11545	COG0039	L-malate dehydrogenase activity
ACWT_RS11570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACWT_RS11690	COG1396	sequence-specific DNA binding
ACWT_RS11705	COG1072	(Pantothenic acid kinase))
ACWT_RS11740	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS11750	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS11755	COG1051	belongs to the nudix hydrolase family
ACWT_RS11765	COG0789	Transcriptional regulator
ACWT_RS11785	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACWT_RS11790	COG1472	Belongs to the glycosyl hydrolase 3 family
ACWT_RS11795	COG1609	Transcriptional regulator
ACWT_RS11805	COG1175	transmembrane transport
ACWT_RS11810	COG0395	ABC-type sugar transport system, permease component
ACWT_RS11815	COG1501	Belongs to the glycosyl hydrolase 31 family
ACWT_RS11830	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACWT_RS11840	COG1122	ATPase activity
ACWT_RS11855	COG0310	cobalt ion transport
ACWT_RS11860	COG5002	protein histidine kinase activity
ACWT_RS11880	COG5002	protein histidine kinase activity
ACWT_RS11900	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS11910	COG1129	ABC transporter
ACWT_RS11915	COG1879	ABC-type sugar transport system periplasmic component
ACWT_RS11935	COG0483	inositol monophosphate 1-phosphatase activity
ACWT_RS11940	COG0515	serine threonine protein kinase
ACWT_RS11940	COG2815	serine threonine protein kinase
ACWT_RS11960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACWT_RS11965	COG1012	belongs to the aldehyde dehydrogenase family
ACWT_RS11970	COG3842	ATPase activity
ACWT_RS11975	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACWT_RS11980	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACWT_RS11985	COG1177	transmembrane transport
ACWT_RS11990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACWT_RS11995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACWT_RS12000	COG0789	Transcriptional regulator
ACWT_RS12010	COG0745	RESPONSE REGULATOR receiver
ACWT_RS12020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACWT_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
ACWT_RS12040	COG2208	phosphoserine phosphatase activity
ACWT_RS12045	COG1472	Belongs to the glycosyl hydrolase 3 family
ACWT_RS12055	COG1175	transmembrane transport
ACWT_RS12065	COG1609	Transcriptional regulator
ACWT_RS12070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS12075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACWT_RS12095	COG0840	transmembrane signaling receptor activity
ACWT_RS12100	COG3191	aminopeptidase activity
ACWT_RS12120	COG0702	epimerase
ACWT_RS12125	COG1733	regulation of RNA biosynthetic process
ACWT_RS12140	COG3300	MHYT domain
ACWT_RS12140	COG5001	Diguanylate cyclase
ACWT_RS12145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACWT_RS12150	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACWT_RS12150	COG1024	Enoyl-CoA hydratase
ACWT_RS12155	COG0183	Belongs to the thiolase family
ACWT_RS12160	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS12185	COG1074	ATP-dependent DNA helicase activity
ACWT_RS12185	COG1074	ATP-dependent DNA helicase activity
ACWT_RS12220	COG2197	response regulator
ACWT_RS12225	COG4585	Histidine kinase
ACWT_RS12245	COG0601	transmembrane transport
ACWT_RS12250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACWT_RS12265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS12275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS12305	COG0656	L-ascorbic acid biosynthetic process
ACWT_RS12345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACWT_RS12350	COG1126	abc transporter atp-binding protein
ACWT_RS12355	COG0765	amino acid transport
ACWT_RS12360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACWT_RS12365	COG4521	taurine ABC transporter
ACWT_RS12380	COG0366	Alpha amylase catalytic
ACWT_RS12390	COG3237	CsbD-like
ACWT_RS12395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS12400	COG2409	Drug exporters of the RND superfamily
ACWT_RS12420	COG1132	(ABC) transporter
ACWT_RS12435	COG0372	Belongs to the citrate synthase family
ACWT_RS12455	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACWT_RS12455	COG0596	Alpha beta hydrolase
ACWT_RS12495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACWT_RS12500	COG2146	nitrite reductase [NAD(P)H] activity
ACWT_RS12505	COG2223	nitrite transmembrane transporter activity
ACWT_RS12535	COG1136	(ABC) transporter
ACWT_RS12540	COG1136	(ABC) transporter
ACWT_RS12545	COG0395	ABC-type sugar transport system, permease component
ACWT_RS12550	COG1175	transmembrane transport
ACWT_RS12555	COG1653	transport
ACWT_RS12560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACWT_RS12570	COG4733	cellulase activity
ACWT_RS12570	COG5297	Belongs to the glycosyl hydrolase family 6
ACWT_RS12585	COG0009	L-threonylcarbamoyladenylate synthase
ACWT_RS12605	COG4213	ABC transporter substrate-binding protein
ACWT_RS12610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACWT_RS12620	COG2409	Drug exporters of the RND superfamily
ACWT_RS12625	COG0247	lactate metabolic process
ACWT_RS12630	COG0277	FAD linked oxidase domain protein
ACWT_RS12635	COG0277	FAD linked oxidase domain protein
ACWT_RS12645	COG0574	Belongs to the PEP-utilizing enzyme family
ACWT_RS12645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACWT_RS12665	COG0514	ATP-dependent DNA helicase (RecQ)
ACWT_RS12675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACWT_RS12695	COG0297	glycogen (starch) synthase activity
ACWT_RS12715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACWT_RS12745	COG0326	Molecular chaperone. Has ATPase activity
ACWT_RS12775	COG1309	transcriptional regulator
ACWT_RS12790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACWT_RS12835	COG0477	Major facilitator Superfamily
ACWT_RS12840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACWT_RS12855	COG4988	ABC transporter
ACWT_RS12860	COG1294	oxidase, subunit
ACWT_RS12865	COG1271	oxidase subunit
ACWT_RS12875	COG0501	Belongs to the peptidase M48B family
ACWT_RS12880	COG0791	NLP P60 protein
ACWT_RS12880	COG3883	PFAM NLP P60 protein
ACWT_RS12885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACWT_RS12910	COG2188	Transcriptional regulator
ACWT_RS12915	COG0159	tryptophan synthase activity
ACWT_RS12920	COG0133	tryptophan synthase activity
ACWT_RS12935	COG0745	RESPONSE REGULATOR receiver
ACWT_RS12940	COG2205	protein histidine kinase activity
ACWT_RS12970	COG5297	Belongs to the glycosyl hydrolase family 6
ACWT_RS12985	COG3345	alpha-galactosidase
ACWT_RS12990	COG3507	Belongs to the glycosyl hydrolase 43 family
ACWT_RS13005	COG3693	PFAM glycoside hydrolase, family 10
ACWT_RS13015	COG3693	PFAM glycoside hydrolase, family 10
ACWT_RS13060	COG1620	l-lactate permease
ACWT_RS13065	COG1228	amidohydrolase
ACWT_RS13075	COG3328	transposase activity
ACWT_RS13135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACWT_RS13140	COG0166	Belongs to the GPI family
ACWT_RS13160	COG0515	serine threonine protein kinase
ACWT_RS13195	COG1309	transcriptional regulator
ACWT_RS13205	COG2076	Multidrug Resistance protein
ACWT_RS13240	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACWT_RS13245	COG0745	RESPONSE REGULATOR receiver
ACWT_RS13260	COG0601	transmembrane transport
ACWT_RS13265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACWT_RS13270	COG0444	Belongs to the ABC transporter superfamily
ACWT_RS13275	COG4608	Belongs to the ABC transporter superfamily
ACWT_RS13300	COG1940	carbohydrate kinase activity
ACWT_RS13330	COG1609	Transcriptional regulator
ACWT_RS13340	COG0406	alpha-ribazole phosphatase activity
ACWT_RS13375	COG0745	RESPONSE REGULATOR receiver
ACWT_RS13380	COG2205	protein histidine kinase activity
ACWT_RS13390	COG1136	(ABC) transporter
ACWT_RS13390	COG0577	efflux transmembrane transporter activity
ACWT_RS13395	COG0577	efflux transmembrane transporter activity
ACWT_RS13395	COG1136	(ABC) transporter
ACWT_RS13420	COG3384	dioxygenase
ACWT_RS13435	COG3718	enzyme involved in inositol metabolism
ACWT_RS13440	COG3962	Belongs to the TPP enzyme family
ACWT_RS13445	COG1082	Xylose isomerase domain protein TIM barrel
ACWT_RS13455	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS13465	COG0673	inositol 2-dehydrogenase activity
ACWT_RS13480	COG3396	Phenylacetate-CoA oxygenase
ACWT_RS13485	COG3460	Phenylacetate-CoA oxygenase
ACWT_RS13490	COG3396	Phenylacetate-CoA oxygenase
ACWT_RS13500	COG2151	metal-sulfur cluster biosynthetic enzyme
ACWT_RS13505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACWT_RS13515	COG2226	methyltransferase
ACWT_RS13530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACWT_RS13535	COG1132	(ABC) transporter
ACWT_RS13540	COG1408	metallophosphoesterase
ACWT_RS13565	COG0515	serine threonine protein kinase
ACWT_RS13570	COG0531	amino acid
ACWT_RS13585	COG2124	cytochrome p450
ACWT_RS13595	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACWT_RS13615	COG5001	Diguanylate cyclase
ACWT_RS13615	COG3300	MHYT domain
ACWT_RS13630	COG4279	zinc finger
ACWT_RS13660	COG3022	response to hydroperoxide
ACWT_RS13670	COG1476	TRANSCRIPTIONal
ACWT_RS13705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACWT_RS13725	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACWT_RS13735	COG2816	NAD+ diphosphatase activity
ACWT_RS13775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACWT_RS13805	COG0667	Aldo Keto reductase
ACWT_RS13870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACWT_RS13880	COG1324	tolerance protein
ACWT_RS13890	COG3540	Alkaline phosphatase
ACWT_RS13915	COG3706	GGDEF domain
ACWT_RS13930	COG3300	MHYT domain
ACWT_RS13930	COG5001	Diguanylate cyclase
ACWT_RS13935	COG3511	phospholipase C
ACWT_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS13970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACWT_RS13975	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS14015	COG1509	lysine 2,3-aminomutase activity
ACWT_RS14020	COG0604	alcohol dehydrogenase
ACWT_RS14025	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ACWT_RS14030	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACWT_RS14035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACWT_RS14040	COG1607	acyl-coa hydrolase
ACWT_RS14055	COG0463	Glycosyl transferase, family 2
ACWT_RS14100	COG0640	Transcriptional regulator
ACWT_RS14115	COG0778	Nitroreductase
ACWT_RS14130	COG1136	(ABC) transporter
ACWT_RS14130	COG0577	efflux transmembrane transporter activity
ACWT_RS14145	COG4214	carbohydrate transport
ACWT_RS14150	COG4213	ABC transporter substrate-binding protein
ACWT_RS14160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACWT_RS14165	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACWT_RS14170	COG2080	2 iron, 2 sulfur cluster binding
ACWT_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS14225	COG0693	protein deglycase activity
ACWT_RS14250	COG0488	(ABC) transporter
ACWT_RS14260	COG0583	DNA-binding transcription factor activity
ACWT_RS14265	COG0183	Belongs to the thiolase family
ACWT_RS14275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACWT_RS14280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS14300	COG0411	ABC transporter
ACWT_RS14310	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS14315	COG0596	Alpha beta hydrolase
ACWT_RS14355	COG1984	allophanate hydrolase subunit 2
ACWT_RS14360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACWT_RS14380	COG3250	beta-galactosidase activity
ACWT_RS14390	COG2201	protein-glutamate methylesterase activity
ACWT_RS14405	COG2201	protein-glutamate methylesterase activity
ACWT_RS14415	COG0701	Predicted permease
ACWT_RS14430	COG1690	Belongs to the RtcB family
ACWT_RS14445	COG5001	Diguanylate cyclase
ACWT_RS14445	COG3300	MHYT domain
ACWT_RS14475	COG0436	Aminotransferase
ACWT_RS14490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACWT_RS14525	COG0242	peptide deformylase activity
ACWT_RS14530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACWT_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS14545	COG0783	Belongs to the Dps family
ACWT_RS14570	COG0028	Belongs to the TPP enzyme family
ACWT_RS14595	COG0714	Associated with various cellular activities
ACWT_RS14620	COG5001	Diguanylate cyclase
ACWT_RS14620	COG3300	MHYT domain
ACWT_RS14635	COG0531	amino acid
ACWT_RS14660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACWT_RS14670	COG3973	AAA domain
ACWT_RS14680	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACWT_RS14700	COG2801	Transposase and inactivated derivatives
ACWT_RS14700	COG3415	Transposase
ACWT_RS14725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS14770	COG2192	nodulation
ACWT_RS14780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACWT_RS14790	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS14795	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACWT_RS14795	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACWT_RS14805	COG0859	PFAM glycosyl transferase family 9
ACWT_RS14935	COG1742	UPF0060 membrane protein
ACWT_RS14945	COG0456	acetyltransferase
ACWT_RS14970	COG0494	nUDIX hydrolase
ACWT_RS14975	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACWT_RS14975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACWT_RS15010	COG0024	Methionine aminopeptidase
ACWT_RS15035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS15060	COG0583	DNA-binding transcription factor activity
ACWT_RS15115	COG2815	serine threonine protein kinase
ACWT_RS15115	COG0515	serine threonine protein kinase
ACWT_RS15165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACWT_RS15185	COG1522	sequence-specific DNA binding
ACWT_RS15260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS15275	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACWT_RS15280	COG0022	dehydrogenase e1 component
ACWT_RS15285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACWT_RS15290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACWT_RS15315	COG0673	inositol 2-dehydrogenase activity
ACWT_RS15320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACWT_RS15325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACWT_RS15335	COG2226	methyltransferase
ACWT_RS15350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACWT_RS15365	COG0456	acetyltransferase
ACWT_RS15370	COG0277	FAD linked oxidase domain protein
ACWT_RS15370	COG0247	lactate metabolic process
ACWT_RS15380	COG3629	intracellular signal transduction
ACWT_RS15380	COG3903	Transcriptional regulator
ACWT_RS15395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACWT_RS15400	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACWT_RS15405	COG2319	Wd-40 repeat
ACWT_RS15430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACWT_RS15445	COG4677	pectinesterase activity
ACWT_RS15510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS15515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS15580	COG4585	Histidine kinase
ACWT_RS15585	COG2197	response regulator
ACWT_RS15635	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACWT_RS15640	COG1737	Transcriptional regulator
ACWT_RS15645	COG3876	Protein conserved in bacteria
ACWT_RS15650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACWT_RS15655	COG1653	transport
ACWT_RS15660	COG1175	transmembrane transport
ACWT_RS15665	COG0395	ABC-type sugar transport system, permease component
ACWT_RS15695	COG2205	protein histidine kinase activity
ACWT_RS15700	COG0745	RESPONSE REGULATOR receiver
ACWT_RS15725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACWT_RS15730	COG1131	(ABC) transporter
ACWT_RS15765	COG2304	oxidoreductase activity
ACWT_RS15775	COG2197	response regulator
ACWT_RS15800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACWT_RS15805	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS15860	COG3287	FIST C domain
ACWT_RS15860	COG2200	EAL domain
ACWT_RS15860	COG2199	diguanylate cyclase activity
ACWT_RS15950	COG0431	NADPH-dependent FMN reductase
ACWT_RS15955	COG3795	YCII-related domain
ACWT_RS15960	COG4941	Belongs to the sigma-70 factor family
ACWT_RS15990	COG0387	Pfam Sodium calcium exchanger
ACWT_RS16005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACWT_RS16005	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACWT_RS16025	COG0745	RESPONSE REGULATOR receiver
ACWT_RS16030	COG2205	protein histidine kinase activity
ACWT_RS16035	COG0667	Aldo Keto reductase
ACWT_RS16075	COG1131	(ABC) transporter
ACWT_RS16095	COG1968	undecaprenyl-diphosphatase activity
ACWT_RS16110	COG1011	Hydrolase
ACWT_RS16130	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACWT_RS16135	COG0586	Pfam SNARE associated Golgi protein
ACWT_RS16245	COG2755	lipolytic protein G-D-S-L family
ACWT_RS16295	COG2201	protein-glutamate methylesterase activity
ACWT_RS16300	COG2205	protein histidine kinase activity
ACWT_RS16305	COG0745	RESPONSE REGULATOR receiver
ACWT_RS16355	COG4585	Histidine kinase
ACWT_RS16370	COG2814	Major facilitator Superfamily
ACWT_RS16455	COG5002	protein histidine kinase activity
ACWT_RS16510	COG5002	protein histidine kinase activity
ACWT_RS16510	COG5001	Diguanylate cyclase
ACWT_RS16510	COG3447	MASE1 domain protein
ACWT_RS16520	COG5002	protein histidine kinase activity
ACWT_RS16520	COG2205	protein histidine kinase activity
ACWT_RS16520	COG0784	Response regulator, receiver
ACWT_RS16525	COG3300	MHYT domain
ACWT_RS16525	COG5001	Diguanylate cyclase
ACWT_RS16555	COG3511	phospholipase C
ACWT_RS16585	COG1606	tRNA processing
ACWT_RS16615	COG0784	Response regulator, receiver
ACWT_RS16615	COG4191	Histidine kinase
ACWT_RS16680	COG4941	Belongs to the sigma-70 factor family
ACWT_RS16705	COG3409	Peptidoglycan-binding domain 1 protein
ACWT_RS16715	COG5001	Diguanylate cyclase
ACWT_RS16725	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACWT_RS16755	COG0443	Heat shock 70 kDa protein
ACWT_RS16775	COG5002	protein histidine kinase activity
ACWT_RS16780	COG2203	Gaf domain
ACWT_RS16780	COG2199	diguanylate cyclase activity
ACWT_RS16790	COG0745	RESPONSE REGULATOR receiver
ACWT_RS16845	COG3706	GGDEF domain
ACWT_RS16880	COG5002	protein histidine kinase activity
ACWT_RS16905	COG0840	transmembrane signaling receptor activity
ACWT_RS16930	COG1295	ribonuclease BN
ACWT_RS16935	COG1309	transcriptional regulator
ACWT_RS16970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACWT_RS16975	COG2205	protein histidine kinase activity
ACWT_RS16980	COG5002	protein histidine kinase activity
ACWT_RS17005	COG0515	serine threonine protein kinase
ACWT_RS17005	COG2815	serine threonine protein kinase
ACWT_RS17020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACWT_RS17155	COG1090	epimerase
ACWT_RS17240	COG5001	Diguanylate cyclase
ACWT_RS17245	COG3903	Transcriptional regulator
ACWT_RS17245	COG3629	intracellular signal transduction
ACWT_RS17260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACWT_RS17265	COG4251	negative regulation of phosphorylation
ACWT_RS17305	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ACWT_RS17310	COG5002	protein histidine kinase activity
ACWT_RS17325	COG1982	Orn Lys Arg decarboxylase major
ACWT_RS17335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACWT_RS17450	COG0515	serine threonine protein kinase
ACWT_RS17495	COG2197	response regulator
ACWT_RS17540	COG0577	efflux transmembrane transporter activity
ACWT_RS17540	COG1136	(ABC) transporter
ACWT_RS17545	COG4585	Histidine kinase
ACWT_RS17565	COG0492	ferredoxin-NADP+ reductase activity
ACWT_RS17625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACWT_RS17625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACWT_RS17665	COG1335	isochorismatase
ACWT_RS17675	COG2267	carboxylic ester hydrolase activity
ACWT_RS17685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACWT_RS17725	COG5001	Diguanylate cyclase
ACWT_RS17725	COG3300	MHYT domain
ACWT_RS17740	COG2319	Wd-40 repeat
ACWT_RS17745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACWT_RS17765	COG2815	serine threonine protein kinase
ACWT_RS17765	COG0515	serine threonine protein kinase
ACWT_RS17780	COG1609	Transcriptional regulator
ACWT_RS17845	COG3209	COG3209 Rhs family protein
ACWT_RS17880	COG0840	transmembrane signaling receptor activity
ACWT_RS17910	COG4124	Belongs to the glycosyl hydrolase 26 family
ACWT_RS17920	COG1940	carbohydrate kinase activity
ACWT_RS17935	COG1846	Transcriptional regulator
ACWT_RS17940	COG3387	PFAM Glycoside hydrolase 15-related
ACWT_RS17955	COG3940	Belongs to the glycosyl hydrolase 43 family
ACWT_RS17985	COG1131	(ABC) transporter
ACWT_RS17990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACWT_RS18005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACWT_RS18020	COG0561	phosphatase activity
ACWT_RS18030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACWT_RS18035	COG1940	carbohydrate kinase activity
ACWT_RS18045	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS18050	COG1082	Xylose isomerase domain protein TIM barrel
ACWT_RS18055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACWT_RS18060	COG1088	dTDP-glucose 4,6-dehydratase activity
ACWT_RS18065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACWT_RS18080	COG0395	ABC-type sugar transport system, permease component
ACWT_RS18085	COG1175	transmembrane transport
ACWT_RS18110	COG1733	regulation of RNA biosynthetic process
ACWT_RS18150	COG4251	negative regulation of phosphorylation
ACWT_RS18160	COG0604	alcohol dehydrogenase
ACWT_RS18160	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS18160	COG3321	synthase
ACWT_RS18185	COG4999	Histidine kinase
ACWT_RS18185	COG2205	protein histidine kinase activity
ACWT_RS18185	COG3437	response regulator, receiver
ACWT_RS18185	COG3850	Histidine kinase
ACWT_RS18195	COG0840	transmembrane signaling receptor activity
ACWT_RS18200	COG1744	ABC transporter substrate-binding protein PnrA-like
ACWT_RS18205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACWT_RS18230	COG0640	Transcriptional regulator
ACWT_RS18310	COG1918	ferrous iron import across plasma membrane
ACWT_RS18310	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACWT_RS18320	COG1278	Cold shock
ACWT_RS18335	COG3979	chitinase
ACWT_RS18340	COG3469	chitinase activity
ACWT_RS18370	COG2205	protein histidine kinase activity
ACWT_RS18375	COG2409	Drug exporters of the RND superfamily
ACWT_RS18455	COG1597	lipid kinase activity
ACWT_RS18520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACWT_RS18535	COG2755	lipolytic protein G-D-S-L family
ACWT_RS18560	COG2172	sigma factor antagonist activity
ACWT_RS18560	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS18560	COG2208	phosphoserine phosphatase activity
ACWT_RS18575	COG0765	amino acid transport
ACWT_RS18625	COG2261	transglycosylase associated protein
ACWT_RS18675	COG4172	Belongs to the ABC transporter superfamily
ACWT_RS18695	COG1902	pentaerythritol trinitrate reductase activity
ACWT_RS18740	COG4585	Histidine kinase
ACWT_RS18760	COG1136	(ABC) transporter
ACWT_RS18870	COG3693	PFAM glycoside hydrolase, family 10
ACWT_RS18870	COG3507	Belongs to the glycosyl hydrolase 43 family
ACWT_RS18870	COG2382	esterase
ACWT_RS18890	COG0519	Catalyzes the synthesis of GMP from XMP
ACWT_RS18895	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACWT_RS18900	COG0596	Alpha beta hydrolase
ACWT_RS18910	COG2197	response regulator
ACWT_RS18915	COG4585	Histidine kinase
ACWT_RS18935	COG3706	GGDEF domain
ACWT_RS19005	COG1609	Transcriptional regulator
ACWT_RS19020	COG1175	transmembrane transport
ACWT_RS19025	COG0395	ABC-type sugar transport system, permease component
ACWT_RS19040	COG1132	(ABC) transporter
ACWT_RS19060	COG2259	Doxx family
ACWT_RS19115	COG0583	DNA-binding transcription factor activity
ACWT_RS19135	COG2226	methyltransferase
ACWT_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS19200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACWT_RS19205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACWT_RS19210	COG1414	Transcriptional regulator
ACWT_RS19215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACWT_RS19220	COG4941	Belongs to the sigma-70 factor family
ACWT_RS19225	COG3795	YCII-related domain
ACWT_RS19235	COG2072	flavoprotein involved in K transport
ACWT_RS19270	COG5001	Diguanylate cyclase
ACWT_RS19280	COG2816	NAD+ diphosphatase activity
ACWT_RS19390	COG0142	geranyltranstransferase activity
ACWT_RS19395	COG0477	Major facilitator Superfamily
ACWT_RS19405	COG0531	amino acid
ACWT_RS19415	COG0583	DNA-binding transcription factor activity
ACWT_RS19420	COG0483	inositol monophosphate 1-phosphatase activity
ACWT_RS19490	COG2124	cytochrome p450
ACWT_RS19500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACWT_RS19515	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS19565	COG0628	permease
ACWT_RS19595	COG2909	trisaccharide binding
ACWT_RS19605	COG2909	trisaccharide binding
ACWT_RS19620	COG0531	amino acid
ACWT_RS19625	COG2235	arginine
ACWT_RS19630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACWT_RS19635	COG0549	Belongs to the carbamate kinase family
ACWT_RS19670	COG0477	Major facilitator Superfamily
ACWT_RS19695	COG1597	lipid kinase activity
ACWT_RS19750	COG0531	amino acid
ACWT_RS19765	COG0477	Major facilitator Superfamily
ACWT_RS19790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACWT_RS19795	COG0406	alpha-ribazole phosphatase activity
ACWT_RS19820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACWT_RS19840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACWT_RS19880	COG0640	Transcriptional regulator
ACWT_RS19890	COG0745	RESPONSE REGULATOR receiver
ACWT_RS19895	COG5002	protein histidine kinase activity
ACWT_RS19930	COG0789	Transcriptional regulator
ACWT_RS20005	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ACWT_RS20005	COG1672	PFAM Archaeal ATPase
ACWT_RS20015	COG3173	Aminoglycoside phosphotransferase
ACWT_RS20020	COG1309	transcriptional regulator
ACWT_RS20040	COG0515	serine threonine protein kinase
ACWT_RS20125	COG2770	Histidine kinase
ACWT_RS20125	COG2208	phosphoserine phosphatase activity
ACWT_RS20145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACWT_RS20240	COG2197	response regulator
ACWT_RS20255	COG4104	PAAR repeat-containing protein
ACWT_RS20265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACWT_RS20295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS20305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS20325	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACWT_RS20330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACWT_RS20335	COG2197	response regulator
ACWT_RS20365	COG1595	DNA-templated transcription, initiation
ACWT_RS20385	COG0463	Glycosyl transferase, family 2
ACWT_RS20405	COG0076	glutamate decarboxylase activity
ACWT_RS20450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACWT_RS20455	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACWT_RS20465	COG2020	methyltransferase activity
ACWT_RS20470	COG1556	Lactate utilization protein
ACWT_RS20475	COG1139	Iron-sulfur cluster binding protein
ACWT_RS20480	COG0247	lactate metabolic process
ACWT_RS20485	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACWT_RS20495	COG1129	ABC transporter
ACWT_RS20500	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS20515	COG2186	Transcriptional regulator
ACWT_RS20530	COG2186	Transcriptional regulator
ACWT_RS20535	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS20590	COG2186	Transcriptional regulator
ACWT_RS20600	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS20610	COG2186	Transcriptional regulator
ACWT_RS20615	COG2267	carboxylic ester hydrolase activity
ACWT_RS20620	COG5002	protein histidine kinase activity
ACWT_RS20625	COG0745	RESPONSE REGULATOR receiver
ACWT_RS20640	COG0577	efflux transmembrane transporter activity
ACWT_RS20640	COG1136	(ABC) transporter
ACWT_RS20645	COG0577	efflux transmembrane transporter activity
ACWT_RS20645	COG1136	(ABC) transporter
ACWT_RS20670	COG0640	Transcriptional regulator
ACWT_RS20710	COG2226	methyltransferase
ACWT_RS20725	COG1595	DNA-templated transcription, initiation
ACWT_RS20770	COG3795	YCII-related domain
ACWT_RS20775	COG4941	Belongs to the sigma-70 factor family
ACWT_RS20835	COG1309	transcriptional regulator
ACWT_RS20850	COG2197	response regulator
ACWT_RS20855	COG4585	Histidine kinase
ACWT_RS20870	COG2267	carboxylic ester hydrolase activity
ACWT_RS20880	COG3795	YCII-related domain
ACWT_RS20885	COG4941	Belongs to the sigma-70 factor family
ACWT_RS20905	COG0681	Belongs to the peptidase S26 family
ACWT_RS20910	COG0583	DNA-binding transcription factor activity
ACWT_RS20925	COG1942	4-Oxalocrotonate Tautomerase
ACWT_RS20950	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS20950	COG2172	sigma factor antagonist activity
ACWT_RS20950	COG2208	phosphoserine phosphatase activity
ACWT_RS20975	COG4221	oxidoreductase activity
ACWT_RS21040	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS21090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACWT_RS21125	COG1131	(ABC) transporter
ACWT_RS21130	COG0842	Transport permease protein
ACWT_RS21135	COG4585	Histidine kinase
ACWT_RS21140	COG2197	response regulator
ACWT_RS21145	COG1191	sigma factor activity
ACWT_RS21155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACWT_RS21160	COG0488	(ABC) transporter
ACWT_RS21165	COG4974	Belongs to the 'phage' integrase family
ACWT_RS21170	COG1968	undecaprenyl-diphosphatase activity
ACWT_RS21190	COG4974	Belongs to the 'phage' integrase family
ACWT_RS21195	COG1506	peptidase
ACWT_RS21195	COG0823	Involved in the tonB-independent uptake of proteins
ACWT_RS21205	COG2226	methyltransferase
ACWT_RS21270	COG1522	sequence-specific DNA binding
ACWT_RS21285	COG0667	Aldo Keto reductase
ACWT_RS21325	COG2197	response regulator
ACWT_RS21345	COG2270	Major facilitator Superfamily
ACWT_RS21400	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ACWT_RS21410	COG4702	Belongs to the UPF0303 family
ACWT_RS21430	COG1846	Transcriptional regulator
ACWT_RS21435	COG1764	response to oxidative stress
ACWT_RS21500	COG0019	diaminopimelate decarboxylase activity
ACWT_RS21550	COG0667	Aldo Keto reductase
ACWT_RS21575	COG0714	Associated with various cellular activities
ACWT_RS21605	COG4221	oxidoreductase activity
ACWT_RS21675	COG0242	peptide deformylase activity
ACWT_RS21690	COG1595	DNA-templated transcription, initiation
ACWT_RS21695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACWT_RS21705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACWT_RS21705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACWT_RS21710	COG0667	Aldo Keto reductase
ACWT_RS21725	COG2226	methyltransferase
ACWT_RS21790	COG0672	)-iron permease
ACWT_RS21795	COG2822	iron ion transport
ACWT_RS21800	COG2837	iron assimilation
ACWT_RS21890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACWT_RS21930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACWT_RS21960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACWT_RS21985	COG1278	Cold shock
ACWT_RS21990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACWT_RS22000	COG2197	response regulator
ACWT_RS22075	COG0346	lactoylglutathione lyase activity
ACWT_RS22085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACWT_RS22090	COG0840	transmembrane signaling receptor activity
ACWT_RS22155	COG1819	glycosyl
ACWT_RS22175	COG1024	Enoyl-CoA hydratase
ACWT_RS22190	COG1024	Enoyl-CoA hydratase
ACWT_RS22195	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACWT_RS22195	COG1902	pentaerythritol trinitrate reductase activity
ACWT_RS22205	COG2814	Major facilitator Superfamily
ACWT_RS22240	COG1760	l-serine dehydratase
ACWT_RS22245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACWT_RS22280	COG1733	regulation of RNA biosynthetic process
ACWT_RS22290	COG1309	transcriptional regulator
ACWT_RS22315	COG1132	(ABC) transporter
ACWT_RS22320	COG1132	(ABC) transporter
ACWT_RS22330	COG0515	serine threonine protein kinase
ACWT_RS22380	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS22405	COG5001	Diguanylate cyclase
ACWT_RS22465	COG2197	response regulator
ACWT_RS22495	COG1733	regulation of RNA biosynthetic process
ACWT_RS22500	COG2910	NAD(P)H-binding
ACWT_RS22535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS22610	COG1881	PFAM PEBP family protein
ACWT_RS22655	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACWT_RS22670	COG0640	Transcriptional regulator
ACWT_RS22690	COG5002	protein histidine kinase activity
ACWT_RS22690	COG3447	MASE1 domain protein
ACWT_RS22690	COG5001	Diguanylate cyclase
ACWT_RS22710	COG0300	oxidoreductase activity
ACWT_RS22715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACWT_RS22715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACWT_RS22740	COG5002	protein histidine kinase activity
ACWT_RS22745	COG2205	protein histidine kinase activity
ACWT_RS22745	COG2202	Pas domain
ACWT_RS22750	COG0395	ABC-type sugar transport system, permease component
ACWT_RS22755	COG1175	transmembrane transport
ACWT_RS22765	COG0789	Transcriptional regulator
ACWT_RS22815	COG0596	Alpha beta hydrolase
ACWT_RS22845	COG3467	pyridoxamine 5'-phosphate
ACWT_RS22860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS22880	COG0640	Transcriptional regulator
ACWT_RS22890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACWT_RS22945	COG2721	sulfolactate sulfo-lyase activity
ACWT_RS22965	COG1609	Transcriptional regulator
ACWT_RS22980	COG0784	Response regulator, receiver
ACWT_RS22990	COG1278	Cold shock
ACWT_RS23000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACWT_RS23015	COG1260	myo-inositol-1-phosphate synthase
ACWT_RS23030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACWT_RS23040	COG0583	DNA-binding transcription factor activity
ACWT_RS23095	COG5001	Diguanylate cyclase
ACWT_RS23125	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS23130	COG2890	protein-(glutamine-N5) methyltransferase activity
ACWT_RS23135	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS23175	COG5002	protein histidine kinase activity
ACWT_RS23180	COG0745	RESPONSE REGULATOR receiver
ACWT_RS23285	COG3300	MHYT domain
ACWT_RS23285	COG5001	Diguanylate cyclase
ACWT_RS23290	COG1404	Belongs to the peptidase S8 family
ACWT_RS23295	COG4251	negative regulation of phosphorylation
ACWT_RS23300	COG1982	Orn Lys Arg decarboxylase major
ACWT_RS23320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACWT_RS23330	COG0778	Nitroreductase
ACWT_RS23350	COG2267	carboxylic ester hydrolase activity
ACWT_RS23395	COG2814	Major facilitator Superfamily
ACWT_RS23400	COG2011	ABC-type metal ion transport system permease component
ACWT_RS23405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACWT_RS23440	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS23475	COG1064	alcohol dehydrogenase
ACWT_RS23520	COG1476	TRANSCRIPTIONal
ACWT_RS23535	COG3629	intracellular signal transduction
ACWT_RS23535	COG3903	Transcriptional regulator
ACWT_RS23580	COG2357	RelA SpoT domain protein
ACWT_RS23610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS23630	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS23655	COG3437	response regulator, receiver
ACWT_RS23655	COG4999	Histidine kinase
ACWT_RS23655	COG3850	Histidine kinase
ACWT_RS23655	COG2205	protein histidine kinase activity
ACWT_RS23660	COG4251	negative regulation of phosphorylation
ACWT_RS23685	COG0745	RESPONSE REGULATOR receiver
ACWT_RS23720	COG5001	Diguanylate cyclase
ACWT_RS23755	COG0300	oxidoreductase activity
ACWT_RS23765	COG0667	Aldo Keto reductase
ACWT_RS23825	COG1691	(AIR) carboxylase
ACWT_RS23830	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ACWT_RS23870	COG0477	Major facilitator Superfamily
ACWT_RS23890	COG2226	methyltransferase
ACWT_RS23915	COG5002	protein histidine kinase activity
ACWT_RS24025	COG4762	Protein conserved in bacteria
ACWT_RS24110	COG0477	Major facilitator Superfamily
ACWT_RS24180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACWT_RS24210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACWT_RS24225	COG3239	Fatty acid desaturase
ACWT_RS24240	COG1376	ErfK ybiS ycfS ynhG family protein
ACWT_RS24255	COG1595	DNA-templated transcription, initiation
ACWT_RS24350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACWT_RS24380	COG3693	PFAM glycoside hydrolase, family 10
ACWT_RS24395	COG2755	lipolytic protein G-D-S-L family
ACWT_RS24395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACWT_RS24415	COG0840	transmembrane signaling receptor activity
ACWT_RS24445	COG0583	DNA-binding transcription factor activity
ACWT_RS24545	COG0393	Putative heavy-metal-binding
ACWT_RS24550	COG0393	Putative heavy-metal-binding
ACWT_RS24665	COG2801	Transposase and inactivated derivatives
ACWT_RS24665	COG3415	Transposase
ACWT_RS24790	COG0515	serine threonine protein kinase
ACWT_RS24795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACWT_RS24800	COG0697	spore germination
ACWT_RS24805	COG1686	Belongs to the peptidase S11 family
ACWT_RS24845	COG1335	isochorismatase
ACWT_RS24875	COG0714	Associated with various cellular activities
ACWT_RS24920	COG0714	Associated with various cellular activities
ACWT_RS24925	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ACWT_RS24975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACWT_RS24995	COG0745	RESPONSE REGULATOR receiver
ACWT_RS25000	COG2205	protein histidine kinase activity
ACWT_RS25025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACWT_RS25045	COG1716	ATPase activity
ACWT_RS25050	COG0509	glycine decarboxylation via glycine cleavage system
ACWT_RS25095	COG0640	Transcriptional regulator
ACWT_RS25105	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ACWT_RS25110	COG0384	phenazine biosynthesis protein PhzF
ACWT_RS25115	COG3447	MASE1 domain protein
ACWT_RS25115	COG5002	protein histidine kinase activity
ACWT_RS25115	COG5001	Diguanylate cyclase
ACWT_RS25120	COG0488	(ABC) transporter
ACWT_RS25140	COG1649	PFAM Uncharacterised BCR, COG1649
ACWT_RS25145	COG0297	glycogen (starch) synthase activity
ACWT_RS25150	COG5001	Diguanylate cyclase
ACWT_RS25155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACWT_RS25180	COG2816	NAD+ diphosphatase activity
ACWT_RS25225	COG2501	S4 domain
ACWT_RS25240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACWT_RS25245	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS25250	COG1940	carbohydrate kinase activity
ACWT_RS25265	COG4214	carbohydrate transport
ACWT_RS25270	COG1129	ABC transporter
ACWT_RS25280	COG2160	L-arabinose isomerase activity
ACWT_RS25285	COG1609	Transcriptional regulator
ACWT_RS25320	COG3706	GGDEF domain
ACWT_RS25325	COG5006	permease, DMT superfamily
ACWT_RS25330	COG0577	efflux transmembrane transporter activity
ACWT_RS25330	COG1136	(ABC) transporter
ACWT_RS25335	COG1136	(ABC) transporter
ACWT_RS25335	COG0577	efflux transmembrane transporter activity
ACWT_RS25365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACWT_RS25375	COG0840	transmembrane signaling receptor activity
ACWT_RS25380	COG0643	Histidine kinase
ACWT_RS25380	COG2198	Histidine kinase
ACWT_RS25385	COG2201	protein-glutamate methylesterase activity
ACWT_RS25395	COG1136	(ABC) transporter
ACWT_RS25395	COG0577	efflux transmembrane transporter activity
ACWT_RS25400	COG0577	efflux transmembrane transporter activity
ACWT_RS25400	COG1136	(ABC) transporter
ACWT_RS25410	COG2197	response regulator
ACWT_RS25470	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACWT_RS25480	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACWT_RS25490	COG3119	arylsulfatase activity
ACWT_RS25500	COG0671	phosphoesterase, PA-phosphatase related
ACWT_RS25505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACWT_RS25520	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS25525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACWT_RS25540	COG2226	methyltransferase
ACWT_RS25590	COG1309	transcriptional regulator
ACWT_RS25605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACWT_RS25610	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACWT_RS25615	COG1120	ATPase activity
ACWT_RS25625	COG0579	oxidoreductase
ACWT_RS25630	COG2205	protein histidine kinase activity
ACWT_RS25635	COG0745	RESPONSE REGULATOR receiver
ACWT_RS25640	COG0431	NADPH-dependent FMN reductase
ACWT_RS25640	COG1053	succinate dehydrogenase
ACWT_RS25640	COG3976	FMN-binding domain protein
ACWT_RS25645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACWT_RS25645	COG1017	nitric oxide dioxygenase activity
ACWT_RS25655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACWT_RS25685	COG2771	luxR family
ACWT_RS25685	COG2200	EAL domain
ACWT_RS25690	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS25700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACWT_RS25765	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACWT_RS25780	COG4581	dead DEAH box helicase
ACWT_RS25785	COG0546	phosphoglycolate phosphatase activity
ACWT_RS25800	COG0805	protein transport
ACWT_RS25805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACWT_RS25815	COG2378	regulation of single-species biofilm formation
ACWT_RS25825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACWT_RS25875	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACWT_RS25880	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACWT_RS25885	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACWT_RS25895	COG4122	O-methyltransferase activity
ACWT_RS25905	COG1222	aaa ATPase
ACWT_RS25925	COG1994	Peptidase M50
ACWT_RS25925	COG0517	IMP dehydrogenase activity
ACWT_RS25935	COG2197	response regulator
ACWT_RS25940	COG0546	phosphoglycolate phosphatase activity
ACWT_RS25945	COG1136	(ABC) transporter
ACWT_RS25945	COG0577	efflux transmembrane transporter activity
ACWT_RS25950	COG1136	(ABC) transporter
ACWT_RS25950	COG0577	efflux transmembrane transporter activity
ACWT_RS25990	COG2197	response regulator
ACWT_RS26000	COG0215	cysteine-tRNA ligase activity
ACWT_RS26020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS26025	COG0667	Aldo Keto reductase
ACWT_RS26030	COG4585	Histidine kinase
ACWT_RS26050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACWT_RS26080	COG0542	response to heat
ACWT_RS26120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACWT_RS26130	COG0745	RESPONSE REGULATOR receiver
ACWT_RS26135	COG0653	protein targeting
ACWT_RS26165	COG1797	cobyrinic acid a,c-diamide synthase activity
ACWT_RS26190	COG0640	Transcriptional regulator
ACWT_RS26205	COG5001	Diguanylate cyclase
ACWT_RS26215	COG0708	Exodeoxyribonuclease III
ACWT_RS26250	COG1643	Atp-dependent helicase
ACWT_RS26260	COG0745	RESPONSE REGULATOR receiver
ACWT_RS26265	COG4251	negative regulation of phosphorylation
ACWT_RS26320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACWT_RS26330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACWT_RS26340	COG2183	response to ionizing radiation
ACWT_RS26390	COG5297	Belongs to the glycosyl hydrolase family 6
ACWT_RS26405	COG5001	Diguanylate cyclase
ACWT_RS26415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACWT_RS26430	COG2197	response regulator
ACWT_RS26435	COG4585	Histidine kinase
ACWT_RS26440	COG0584	glycerophosphoryl diester phosphodiesterase
ACWT_RS26485	COG3447	MASE1 domain protein
ACWT_RS26485	COG5001	Diguanylate cyclase
ACWT_RS26485	COG5002	protein histidine kinase activity
ACWT_RS26495	COG0515	serine threonine protein kinase
ACWT_RS26515	COG1609	Transcriptional regulator
ACWT_RS26555	COG3866	Pectate lyase
ACWT_RS26565	COG0673	inositol 2-dehydrogenase activity
ACWT_RS26570	COG0246	Mannitol dehydrogenase
ACWT_RS26575	COG1904	glucuronate isomerase
ACWT_RS26580	COG0673	inositol 2-dehydrogenase activity
ACWT_RS26585	COG1609	Transcriptional regulator
ACWT_RS26595	COG1175	transmembrane transport
ACWT_RS26600	COG0395	ABC-type sugar transport system, permease component
ACWT_RS26615	COG0686	Belongs to the AlaDH PNT family
ACWT_RS26635	COG2197	response regulator
ACWT_RS26670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACWT_RS26670	COG0596	Alpha beta hydrolase
ACWT_RS26690	COG1486	melibiose metabolic process
ACWT_RS26695	COG1653	transport
ACWT_RS26710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACWT_RS26760	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ACWT_RS26770	COG1595	DNA-templated transcription, initiation
ACWT_RS26810	COG1653	transport
ACWT_RS26815	COG0395	ABC-type sugar transport system, permease component
ACWT_RS26820	COG0395	ABC-type sugar transport system, permease component
ACWT_RS26850	COG2409	Drug exporters of the RND superfamily
ACWT_RS26885	COG2160	L-arabinose isomerase activity
ACWT_RS26890	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS26895	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS26905	COG1879	ABC-type sugar transport system periplasmic component
ACWT_RS26910	COG1609	Transcriptional regulator
ACWT_RS26920	COG0235	Class ii aldolase
ACWT_RS26945	COG2130	NADP-dependent
ACWT_RS26950	COG1309	transcriptional regulator
ACWT_RS26955	COG0569	domain protein
ACWT_RS26970	COG4251	negative regulation of phosphorylation
ACWT_RS26980	COG0840	transmembrane signaling receptor activity
ACWT_RS26995	COG1131	(ABC) transporter
ACWT_RS27055	COG0583	DNA-binding transcription factor activity
ACWT_RS27060	COG1012	belongs to the aldehyde dehydrogenase family
ACWT_RS27075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACWT_RS27080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACWT_RS27110	COG3458	cephalosporin-C deacetylase activity
ACWT_RS27115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACWT_RS27130	COG0840	transmembrane signaling receptor activity
ACWT_RS27135	COG1461	Dihydroxyacetone kinase
ACWT_RS27140	COG2376	Dihydroxyacetone kinase
ACWT_RS27145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACWT_RS27145	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ACWT_RS27145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACWT_RS27170	COG4682	membrane
ACWT_RS27180	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS27205	COG1309	transcriptional regulator
ACWT_RS27225	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS27230	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS27250	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACWT_RS27250	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACWT_RS27260	COG1476	TRANSCRIPTIONal
ACWT_RS27265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACWT_RS27275	COG1024	Enoyl-CoA hydratase
ACWT_RS27285	COG3940	Belongs to the glycosyl hydrolase 43 family
ACWT_RS27290	COG2199	diguanylate cyclase activity
ACWT_RS27290	COG2200	EAL domain
ACWT_RS27290	COG2202	Pas domain
ACWT_RS27305	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACWT_RS27310	COG2072	flavoprotein involved in K transport
ACWT_RS27320	COG0596	Alpha beta hydrolase
ACWT_RS27335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACWT_RS27350	COG0477	Major facilitator Superfamily
ACWT_RS27355	COG1309	transcriptional regulator
ACWT_RS27370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACWT_RS27385	COG3206	protein involved in exopolysaccharide biosynthesis
ACWT_RS27385	COG0489	protein tyrosine kinase activity
ACWT_RS27410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACWT_RS27415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACWT_RS27435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACWT_RS27465	COG1252	NADH dehydrogenase
ACWT_RS27470	COG1435	thymidine kinase activity
ACWT_RS27480	COG1132	(ABC) transporter
ACWT_RS27485	COG1132	(ABC) transporter
ACWT_RS27505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACWT_RS27510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACWT_RS27530	COG3548	integral membrane protein
ACWT_RS27570	COG3706	GGDEF domain
ACWT_RS27600	COG0395	ABC-type sugar transport system, permease component
ACWT_RS27610	COG1609	Transcriptional regulator
ACWT_RS27625	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
ACWT_RS27655	COG0300	oxidoreductase activity
ACWT_RS27675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACWT_RS27725	COG0601	transmembrane transport
ACWT_RS27730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACWT_RS27775	COG3976	FMN-binding domain protein
ACWT_RS27775	COG1053	succinate dehydrogenase
ACWT_RS27790	COG2755	lipolytic protein G-D-S-L family
ACWT_RS27800	COG2226	methyltransferase
ACWT_RS27805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACWT_RS27810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACWT_RS27820	COG1414	Transcriptional regulator
ACWT_RS27825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACWT_RS27865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACWT_RS27870	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS27875	COG3206	protein involved in exopolysaccharide biosynthesis
ACWT_RS27875	COG0489	protein tyrosine kinase activity
ACWT_RS27960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACWT_RS27970	COG1086	Polysaccharide biosynthesis protein
ACWT_RS27985	COG2197	response regulator
ACWT_RS27990	COG0477	Major facilitator Superfamily
ACWT_RS28000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACWT_RS28010	COG4585	Histidine kinase
ACWT_RS28015	COG2197	response regulator
ACWT_RS28120	COG5001	Diguanylate cyclase
ACWT_RS28120	COG3300	MHYT domain
ACWT_RS28150	COG3511	phospholipase C
ACWT_RS28185	COG1132	(ABC) transporter
ACWT_RS28190	COG1132	(ABC) transporter
ACWT_RS28205	COG0745	RESPONSE REGULATOR receiver
ACWT_RS28210	COG2205	protein histidine kinase activity
ACWT_RS28225	COG2197	response regulator
ACWT_RS28240	COG1132	(ABC) transporter
ACWT_RS28255	COG1309	transcriptional regulator
ACWT_RS28265	COG5479	isomerase activity
ACWT_RS28265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACWT_RS28270	COG0515	serine threonine protein kinase
ACWT_RS28280	COG0823	Involved in the tonB-independent uptake of proteins
ACWT_RS28280	COG1506	peptidase
ACWT_RS28395	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS28405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACWT_RS28410	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS28455	COG1921	L-seryl-tRNASec selenium transferase activity
ACWT_RS28475	COG0709	Synthesizes selenophosphate from selenide and ATP
ACWT_RS28490	COG0437	4 iron, 4 sulfur cluster binding
ACWT_RS28495	COG0243	molybdopterin cofactor binding
ACWT_RS28495	COG3383	formate dehydrogenase (NAD+) activity
ACWT_RS28500	COG0243	molybdopterin cofactor binding
ACWT_RS28845	COG0305	Participates in initiation and elongation during chromosome replication
ACWT_RS28850	COG3415	Transposase
ACWT_RS28850	COG2801	Transposase and inactivated derivatives
ACWT_RS28855	COG0305	Participates in initiation and elongation during chromosome replication
ACWT_RS28915	COG2837	iron assimilation
ACWT_RS29015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACWT_RS29055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACWT_RS29360	COG0840	transmembrane signaling receptor activity
ACWT_RS29370	COG1902	pentaerythritol trinitrate reductase activity
ACWT_RS29410	COG1793	dna ligase
ACWT_RS29515	COG0358	DNA primase activity
ACWT_RS29645	COG3328	transposase activity
ACWT_RS29855	COG1196	nuclear chromosome segregation
ACWT_RS29855	COG0741	lytic transglycosylase activity
ACWT_RS29855	COG0739	heme binding
ACWT_RS29865	COG2358	TRAP transporter, solute receptor (TAXI family
ACWT_RS29870	COG0642	Histidine kinase
ACWT_RS29875	COG0745	RESPONSE REGULATOR receiver
ACWT_RS29925	COG3547	Transposase (IS116 IS110 IS902 family)
ACWT_RS29930	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ACWT_RS29940	COG4974	Belongs to the 'phage' integrase family
ACWT_RS29975	COG3345	alpha-galactosidase
ACWT_RS29995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACWT_RS30015	COG0535	radical SAM domain protein
ACWT_RS30045	COG3321	synthase
ACWT_RS30045	COG0604	alcohol dehydrogenase
ACWT_RS30050	COG0604	alcohol dehydrogenase
ACWT_RS30050	COG3321	synthase
ACWT_RS30055	COG0604	alcohol dehydrogenase
ACWT_RS30055	COG3321	synthase
ACWT_RS30105	COG0477	Major facilitator Superfamily
ACWT_RS30150	COG3328	transposase activity
ACWT_RS30180	COG3903	Transcriptional regulator
ACWT_RS30180	COG3629	intracellular signal transduction
ACWT_RS30200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACWT_RS30205	COG2267	carboxylic ester hydrolase activity
ACWT_RS30210	COG0604	alcohol dehydrogenase
ACWT_RS30210	COG3321	synthase
ACWT_RS30240	COG1509	lysine 2,3-aminomutase activity
ACWT_RS30270	COG3706	GGDEF domain
ACWT_RS30285	COG0395	ABC-type sugar transport system, permease component
ACWT_RS30290	COG1175	transmembrane transport
ACWT_RS30310	COG1674	ftsk spoiiie
ACWT_RS30325	COG2814	Major facilitator Superfamily
ACWT_RS30330	COG1846	Transcriptional regulator
ACWT_RS30380	COG1309	transcriptional regulator
ACWT_RS30395	COG0463	Glycosyl transferase, family 2
ACWT_RS30445	COG0515	serine threonine protein kinase
ACWT_RS30485	COG0745	RESPONSE REGULATOR receiver
ACWT_RS30500	COG2226	methyltransferase
ACWT_RS30500	COG3433	isochorismatase activity
ACWT_RS30500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS30520	COG0596	Alpha beta hydrolase
ACWT_RS30560	COG0475	glutathione-regulated potassium exporter activity
ACWT_RS30575	COG3629	intracellular signal transduction
ACWT_RS30575	COG3903	Transcriptional regulator
ACWT_RS30585	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACWT_RS30595	COG3433	isochorismatase activity
ACWT_RS30595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS30595	COG2226	methyltransferase
ACWT_RS30600	COG1132	(ABC) transporter
ACWT_RS30605	COG1132	(ABC) transporter
ACWT_RS30605	COG2375	cellular response to nickel ion
ACWT_RS30645	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS30650	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS30750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACWT_RS30765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS30770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS30775	COG4221	oxidoreductase activity
ACWT_RS30775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS30775	COG3321	synthase
ACWT_RS30775	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS30795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACWT_RS30810	COG1162	GTPase activity
ACWT_RS30815	COG0745	RESPONSE REGULATOR receiver
ACWT_RS30820	COG3300	MHYT domain
ACWT_RS30820	COG5001	Diguanylate cyclase
ACWT_RS30835	COG4585	Histidine kinase
ACWT_RS30840	COG2197	response regulator
ACWT_RS30980	COG0367	asparagine synthase
ACWT_RS30995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACWT_RS31040	COG1940	carbohydrate kinase activity
ACWT_RS31185	COG2826	transposase and inactivated derivatives, IS30 family
ACWT_RS31190	COG2963	transposase activity
ACWT_RS31325	COG1160	GTP binding
ACWT_RS31330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACWT_RS31340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACWT_RS31345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACWT_RS31355	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS31365	COG2267	carboxylic ester hydrolase activity
ACWT_RS31375	COG1187	pseudouridine synthase activity
ACWT_RS31380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACWT_RS31385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACWT_RS31425	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS31445	COG0686	Belongs to the AlaDH PNT family
ACWT_RS31465	COG0702	epimerase
ACWT_RS31470	COG1733	regulation of RNA biosynthetic process
ACWT_RS31495	COG0494	nUDIX hydrolase
ACWT_RS31500	COG0504	CTP synthase activity
ACWT_RS31540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACWT_RS31575	COG0647	UMP catabolic process
ACWT_RS31615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACWT_RS31620	COG2326	polyphosphate kinase activity
ACWT_RS31630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACWT_RS31635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACWT_RS31640	COG1063	alcohol dehydrogenase
ACWT_RS31645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACWT_RS31645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACWT_RS31650	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACWT_RS31650	COG2213	PTS system mannitol-specific
ACWT_RS31655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACWT_RS31655	COG2213	PTS system mannitol-specific
ACWT_RS31680	COG0563	adenylate kinase activity
ACWT_RS31695	COG0010	Belongs to the arginase family
ACWT_RS31705	COG2340	Cysteine-rich secretory protein family
ACWT_RS31730	COG2094	Belongs to the DNA glycosylase MPG family
ACWT_RS31735	COG3973	AAA domain
ACWT_RS31740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACWT_RS31780	COG0730	response to heat
ACWT_RS31795	COG3833	ABC-type maltose transport systems, permease component
ACWT_RS31815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACWT_RS31820	COG0165	Argininosuccinate lyase
ACWT_RS31850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACWT_RS31855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACWT_RS31860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACWT_RS31865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACWT_RS31910	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACWT_RS31920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACWT_RS31930	COG1472	Belongs to the glycosyl hydrolase 3 family
ACWT_RS31955	COG2949	membrane
ACWT_RS31960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACWT_RS31995	COG0072	phenylalanine-tRNA ligase activity
ACWT_RS31995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACWT_RS32000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACWT_RS32005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACWT_RS32010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACWT_RS32015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACWT_RS32020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACWT_RS32030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACWT_RS32035	COG0140	phosphoribosyl-ATP diphosphatase activity
ACWT_RS32045	COG0765	amino acid transport
ACWT_RS32055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACWT_RS32060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACWT_RS32060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACWT_RS32090	COG0745	RESPONSE REGULATOR receiver
ACWT_RS32105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACWT_RS32110	COG0242	peptide deformylase activity
ACWT_RS32120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACWT_RS32130	COG1758	RNA polymerase activity
ACWT_RS32135	COG0194	GDP metabolic process
ACWT_RS32145	COG0284	orotidine-5'-phosphate decarboxylase activity
ACWT_RS32150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACWT_RS32155	COG0167	dihydroorotate dehydrogenase activity
ACWT_RS32165	COG0505	Belongs to the CarA family
ACWT_RS32170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACWT_RS32175	COG0540	Belongs to the ATCase OTCase family
ACWT_RS32180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACWT_RS32190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACWT_RS32195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACWT_RS32200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACWT_RS32205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACWT_RS32210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACWT_RS32215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACWT_RS32225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACWT_RS32235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACWT_RS32240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACWT_RS32285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACWT_RS32340	COG3964	amidohydrolase
ACWT_RS32345	COG0251	oxidation-reduction process
ACWT_RS32355	COG0831	urea catabolic process
ACWT_RS32360	COG0832	Belongs to the urease beta subunit family
ACWT_RS32385	COG0515	serine threonine protein kinase
ACWT_RS32390	COG0189	ligase activity
ACWT_RS32390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACWT_RS32395	COG4242	Belongs to the peptidase S51 family
ACWT_RS32410	COG0124	histidyl-tRNA synthetase
ACWT_RS32430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACWT_RS32435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACWT_RS32450	COG1862	Preprotein translocase
ACWT_RS32455	COG2255	four-way junction helicase activity
ACWT_RS32460	COG0632	four-way junction helicase activity
ACWT_RS32465	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACWT_RS32495	COG0217	transcriptional regulatory protein
ACWT_RS32500	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ACWT_RS32505	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACWT_RS32515	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS32520	COG1560	Kdo2-lipid A biosynthetic process
ACWT_RS32550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACWT_RS32565	COG2205	protein histidine kinase activity
ACWT_RS32575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACWT_RS32580	COG4106	trans-aconitate 2-methyltransferase activity
ACWT_RS32585	COG0667	Aldo Keto reductase
ACWT_RS32595	COG1278	Cold shock
ACWT_RS32630	COG1472	Belongs to the glycosyl hydrolase 3 family
ACWT_RS32635	COG0514	ATP-dependent DNA helicase (RecQ)
ACWT_RS32675	COG4585	Histidine kinase
ACWT_RS32690	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS32775	COG0483	inositol monophosphate 1-phosphatase activity
ACWT_RS32785	COG0542	response to heat
ACWT_RS32795	COG2309	aminopeptidase activity
ACWT_RS32815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACWT_RS32830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACWT_RS32835	COG2351	hydroxyisourate hydrolase activity
ACWT_RS32840	COG1643	Atp-dependent helicase
ACWT_RS32845	COG2226	methyltransferase
ACWT_RS32875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACWT_RS32955	COG5002	protein histidine kinase activity
ACWT_RS32965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACWT_RS32970	COG0823	Involved in the tonB-independent uptake of proteins
ACWT_RS32975	COG0405	Gamma-glutamyltransferase
ACWT_RS32995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACWT_RS33010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACWT_RS33015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS33020	COG1216	Glycosyl transferase, family 2
ACWT_RS33025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACWT_RS33065	COG1686	Belongs to the peptidase S11 family
ACWT_RS33075	COG1191	sigma factor activity
ACWT_RS33080	COG2226	methyltransferase
ACWT_RS33085	COG3973	AAA domain
ACWT_RS33095	COG1191	sigma factor activity
ACWT_RS33100	COG0513	Belongs to the DEAD box helicase family
ACWT_RS33130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACWT_RS33135	COG1609	Transcriptional regulator
ACWT_RS33145	COG4608	Belongs to the ABC transporter superfamily
ACWT_RS33150	COG0601	transmembrane transport
ACWT_RS33155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACWT_RS33160	COG0444	Belongs to the ABC transporter superfamily
ACWT_RS33195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACWT_RS33200	COG0187	DNA topoisomerase II activity
ACWT_RS33210	COG2197	response regulator
ACWT_RS33220	COG2205	protein histidine kinase activity
ACWT_RS33240	COG1846	Transcriptional regulator
ACWT_RS33245	COG0697	spore germination
ACWT_RS33255	COG0714	Associated with various cellular activities
ACWT_RS33265	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ACWT_RS33340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACWT_RS33370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACWT_RS33375	COG1017	nitric oxide dioxygenase activity
ACWT_RS33375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACWT_RS33395	COG0395	ABC-type sugar transport system, permease component
ACWT_RS33415	COG2197	response regulator
ACWT_RS33430	COG1136	(ABC) transporter
ACWT_RS33430	COG0577	efflux transmembrane transporter activity
ACWT_RS33440	COG2755	lipolytic protein G-D-S-L family
ACWT_RS33455	COG0515	serine threonine protein kinase
ACWT_RS33465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACWT_RS33470	COG1136	(ABC) transporter
ACWT_RS33485	COG0598	Magnesium transport protein CorA
ACWT_RS33495	COG3135	benzoate transporter
ACWT_RS33520	COG0436	Aminotransferase
ACWT_RS33550	COG1673	EVE domain
ACWT_RS33580	COG3509	depolymerase
ACWT_RS33595	COG1136	(ABC) transporter
ACWT_RS33595	COG0577	efflux transmembrane transporter activity
ACWT_RS33605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACWT_RS33715	COG2318	DinB family
ACWT_RS33745	COG0671	phosphoesterase, PA-phosphatase related
ACWT_RS33755	COG1597	lipid kinase activity
ACWT_RS33755	COG1803	Methylglyoxal synthase
ACWT_RS33790	COG0745	RESPONSE REGULATOR receiver
ACWT_RS33830	COG2197	response regulator
ACWT_RS33835	COG4585	Histidine kinase
ACWT_RS33860	COG1335	isochorismatase
ACWT_RS33870	COG0789	Transcriptional regulator
ACWT_RS33885	COG0800	Aldolase
ACWT_RS33915	COG0366	Alpha amylase catalytic
ACWT_RS33920	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS33925	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS33950	COG0673	inositol 2-dehydrogenase activity
ACWT_RS33965	COG3483	tryptophan 2,3-dioxygenase activity
ACWT_RS33970	COG3012	SEC-C Motif Domain Protein
ACWT_RS33975	COG0840	transmembrane signaling receptor activity
ACWT_RS33995	COG0366	Alpha amylase catalytic
ACWT_RS34005	COG1175	transmembrane transport
ACWT_RS34010	COG1653	transport
ACWT_RS34030	COG2308	Evidence 4 Homologs of previously reported genes of
ACWT_RS34030	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS34035	COG0367	asparagine synthase
ACWT_RS34045	COG0542	response to heat
ACWT_RS34065	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACWT_RS34085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACWT_RS34140	COG2197	response regulator
ACWT_RS34145	COG4585	Histidine kinase
ACWT_RS34165	COG1131	(ABC) transporter
ACWT_RS34170	COG0328	RNA-DNA hybrid ribonuclease activity
ACWT_RS34215	COG1653	transport
ACWT_RS34220	COG1793	dna ligase
ACWT_RS34220	COG3285	dna ligase
ACWT_RS34230	COG4585	Histidine kinase
ACWT_RS34235	COG2197	response regulator
ACWT_RS34240	COG5001	Diguanylate cyclase
ACWT_RS34255	COG0071	Belongs to the small heat shock protein (HSP20) family
ACWT_RS34260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACWT_RS34265	COG1278	Cold shock
ACWT_RS34285	COG1595	DNA-templated transcription, initiation
ACWT_RS34300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACWT_RS34320	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS34325	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS34345	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS34350	COG1216	Glycosyl transferase, family 2
ACWT_RS34370	COG2807	transmembrane transport
ACWT_RS34385	COG4249	Peptidase C14 caspase catalytic subunit p20
ACWT_RS34385	COG2319	Wd-40 repeat
ACWT_RS34405	COG0058	SHG alpha-glucan phosphorylase activity
ACWT_RS34425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACWT_RS34450	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS34555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACWT_RS34560	COG0714	Associated with various cellular activities
ACWT_RS34575	COG2304	oxidoreductase activity
ACWT_RS34605	COG5002	protein histidine kinase activity
ACWT_RS34620	COG1132	(ABC) transporter
ACWT_RS34645	COG4260	virion core protein, lumpy skin disease virus
ACWT_RS34695	COG2378	regulation of single-species biofilm formation
ACWT_RS34775	COG0543	2 iron, 2 sulfur cluster binding
ACWT_RS34775	COG0633	Ferredoxin
ACWT_RS34795	COG3300	MHYT domain
ACWT_RS34795	COG5001	Diguanylate cyclase
ACWT_RS34815	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ACWT_RS34870	COG1470	cell adhesion involved in biofilm formation
ACWT_RS34870	COG0366	Alpha amylase catalytic
ACWT_RS34895	COG1609	Transcriptional regulator
ACWT_RS34910	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS34915	COG5001	Diguanylate cyclase
ACWT_RS34930	COG2197	response regulator
ACWT_RS34955	COG2409	Drug exporters of the RND superfamily
ACWT_RS34995	COG2264	protein methyltransferase activity
ACWT_RS35010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACWT_RS35015	COG0156	8-amino-7-oxononanoate synthase activity
ACWT_RS35020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACWT_RS35045	COG0420	3'-5' exonuclease activity
ACWT_RS35050	COG0419	ATPase involved in DNA repair
ACWT_RS35115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACWT_RS35155	COG1793	dna ligase
ACWT_RS35195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACWT_RS35205	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACWT_RS35210	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACWT_RS35225	COG3253	May function as heme-dependent peroxidase
ACWT_RS35230	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ACWT_RS35235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACWT_RS35245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACWT_RS35250	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACWT_RS35255	COG0183	Belongs to the thiolase family
ACWT_RS35260	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACWT_RS35260	COG1024	Enoyl-CoA hydratase
ACWT_RS35270	COG2205	protein histidine kinase activity
ACWT_RS35275	COG0745	RESPONSE REGULATOR receiver
ACWT_RS35290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACWT_RS35295	COG1301	dicarboxylic acid transport
ACWT_RS35300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACWT_RS35305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACWT_RS35310	COG0531	amino acid
ACWT_RS35315	COG0569	domain protein
ACWT_RS35340	COG0756	dUTP diphosphatase activity
ACWT_RS35380	COG5002	protein histidine kinase activity
ACWT_RS35380	COG5001	Diguanylate cyclase
ACWT_RS35380	COG3447	MASE1 domain protein
ACWT_RS35390	COG2860	membrane
ACWT_RS35400	COG2313	pseudouridylate synthase activity
ACWT_RS35435	COG0745	RESPONSE REGULATOR receiver
ACWT_RS35445	COG2198	Histidine kinase
ACWT_RS35445	COG2198	Histidine kinase
ACWT_RS35445	COG0784	Response regulator, receiver
ACWT_RS35445	COG0784	Response regulator, receiver
ACWT_RS35445	COG0643	Histidine kinase
ACWT_RS35445	COG0643	Histidine kinase
ACWT_RS35455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACWT_RS35465	COG2201	protein-glutamate methylesterase activity
ACWT_RS35470	COG0835	chemotaxis
ACWT_RS35485	COG1490	D-aminoacyl-tRNA deacylase activity
ACWT_RS35505	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACWT_RS35530	COG0738	Major facilitator superfamily
ACWT_RS35540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACWT_RS35545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACWT_RS35550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACWT_RS35560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACWT_RS35570	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACWT_RS35575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACWT_RS35580	COG1196	nuclear chromosome segregation
ACWT_RS35595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACWT_RS35615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACWT_RS35625	COG1126	abc transporter atp-binding protein
ACWT_RS35630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACWT_RS35635	COG0765	amino acid transport
ACWT_RS35640	COG0765	amino acid transport
ACWT_RS35645	COG1418	mRNA catabolic process
ACWT_RS35650	COG2137	regulation of response to DNA damage stimulus
ACWT_RS35660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACWT_RS35670	COG1573	uracil-dna glycosylase
ACWT_RS35690	COG2815	serine threonine protein kinase
ACWT_RS35690	COG0515	serine threonine protein kinase
ACWT_RS35695	COG1201	RNA secondary structure unwinding
ACWT_RS35720	COG1842	Phage shock protein A
ACWT_RS35725	COG1396	sequence-specific DNA binding
ACWT_RS35730	COG1546	Belongs to the CinA family
ACWT_RS35730	COG1058	Belongs to the CinA family
ACWT_RS35740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACWT_RS35755	COG1674	ftsk spoiiie
ACWT_RS35770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACWT_RS35775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACWT_RS35785	COG3214	Protein conserved in bacteria
ACWT_RS35790	COG0456	acetyltransferase
ACWT_RS35800	COG1278	Cold shock
ACWT_RS35810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACWT_RS35815	COG0612	Peptidase, M16
ACWT_RS35820	COG1185	polyribonucleotide nucleotidyltransferase activity
ACWT_RS35825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACWT_RS35840	COG0745	RESPONSE REGULATOR receiver
ACWT_RS35845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACWT_RS35855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACWT_RS35860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACWT_RS35875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACWT_RS35890	COG0779	Required for maturation of 30S ribosomal subunits
ACWT_RS35930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACWT_RS35935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACWT_RS35945	COG1012	belongs to the aldehyde dehydrogenase family
ACWT_RS35965	COG1668	transmembrane transport
ACWT_RS35970	COG4152	abc transporter atp-binding protein
ACWT_RS35975	COG2197	response regulator
ACWT_RS35980	COG4585	Histidine kinase
ACWT_RS36000	COG1511	domain protein
ACWT_RS36005	COG3845	ABC transporter
ACWT_RS36015	COG0640	Transcriptional regulator
ACWT_RS36030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACWT_RS36035	COG0750	zinc metalloprotease
ACWT_RS36060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACWT_RS36060	COG2146	nitrite reductase [NAD(P)H] activity
ACWT_RS36075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACWT_RS36085	COG0233	cytoplasmic translational termination
ACWT_RS36090	COG0528	UMP kinase activity
ACWT_RS36095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACWT_RS36100	COG0052	Belongs to the universal ribosomal protein uS2 family
ACWT_RS36105	COG0792	nuclease activity
ACWT_RS36140	COG2188	Transcriptional regulator
ACWT_RS36165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACWT_RS36180	COG0681	Belongs to the peptidase S26 family
ACWT_RS36185	COG0681	Belongs to the peptidase S26 family
ACWT_RS36190	COG0335	large ribosomal subunit rRNA binding
ACWT_RS36195	COG0336	Belongs to the RNA methyltransferase TrmD family
ACWT_RS36200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACWT_RS36205	COG1837	Belongs to the UPF0109 family
ACWT_RS36210	COG0228	four-way junction DNA binding
ACWT_RS36220	COG0442	prolyl-tRNA aminoacylation
ACWT_RS36255	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS36270	COG0463	Glycosyl transferase, family 2
ACWT_RS36280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACWT_RS36280	COG2755	lipolytic protein G-D-S-L family
ACWT_RS36295	COG1215	transferase activity, transferring glycosyl groups
ACWT_RS36310	COG1216	Glycosyl transferase, family 2
ACWT_RS36315	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACWT_RS36345	COG2318	DinB family
ACWT_RS36370	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS36390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACWT_RS36400	COG0571	ribonuclease III activity
ACWT_RS36410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACWT_RS36425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACWT_RS36430	COG0742	ribosomal rna small subunit methyltransferase
ACWT_RS36450	COG1461	Dihydroxyacetone kinase
ACWT_RS36455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACWT_RS36460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACWT_RS36480	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACWT_RS36495	COG0626	cystathionine gamma-synthase activity
ACWT_RS36500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACWT_RS36510	COG1920	GTP binding
ACWT_RS36520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACWT_RS36535	COG0776	regulation of translation
ACWT_RS36540	COG0066	3-isopropylmalate dehydratase activity
ACWT_RS36570	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACWT_RS36575	COG1476	TRANSCRIPTIONal
ACWT_RS36585	COG1131	(ABC) transporter
ACWT_RS36605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACWT_RS36630	COG0612	Peptidase, M16
ACWT_RS36635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACWT_RS36650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACWT_RS36655	COG0473	3-isopropylmalate dehydrogenase activity
ACWT_RS36675	COG0440	acetolactate synthase activity
ACWT_RS36685	COG3300	MHYT domain
ACWT_RS36685	COG5001	Diguanylate cyclase
ACWT_RS36690	COG0129	dihydroxy-acid dehydratase activity
ACWT_RS36705	COG2132	Multicopper oxidase
ACWT_RS36725	COG1609	Transcriptional regulator
ACWT_RS36730	COG5001	Diguanylate cyclase
ACWT_RS36740	COG2133	pyrroloquinoline quinone binding
ACWT_RS36750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACWT_RS36760	COG0154	amidase activity
ACWT_RS36765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACWT_RS36775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACWT_RS36785	COG0482	sulfurtransferase activity
ACWT_RS36795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACWT_RS36800	COG2086	electron transfer activity
ACWT_RS36805	COG2149	membrane
ACWT_RS36825	COG1595	DNA-templated transcription, initiation
ACWT_RS36835	COG0443	Heat shock 70 kDa protein
ACWT_RS36855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACWT_RS36860	COG1119	ATPase activity
ACWT_RS36875	COG2902	Dehydrogenase
ACWT_RS36895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACWT_RS36895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACWT_RS36900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACWT_RS36910	COG1703	isobutyryl-CoA mutase activity
ACWT_RS36915	COG0183	Belongs to the thiolase family
ACWT_RS36935	COG3046	protein related to deoxyribodipyrimidine photolyase
ACWT_RS36950	COG4133	protoheme IX ABC transporter activity
ACWT_RS36980	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ACWT_RS36995	COG1674	ftsk spoiiie
ACWT_RS37005	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACWT_RS37040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACWT_RS37050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACWT_RS37055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACWT_RS37060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACWT_RS37065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACWT_RS37070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACWT_RS37075	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACWT_RS37080	COG0356	it plays a direct role in the translocation of protons across the membrane
ACWT_RS37090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACWT_RS37095	COG0702	epimerase
ACWT_RS37100	COG0251	oxidation-reduction process
ACWT_RS37110	COG0009	L-threonylcarbamoyladenylate synthase
ACWT_RS37125	COG2890	protein-(glutamine-N5) methyltransferase activity
ACWT_RS37145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACWT_RS37150	COG0254	rRNA binding
ACWT_RS37170	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ACWT_RS37180	COG0083	homoserine kinase activity
ACWT_RS37190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACWT_RS37195	COG1846	Transcriptional regulator
ACWT_RS37200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACWT_RS37210	COG0460	homoserine dehydrogenase
ACWT_RS37220	COG0018	arginyl-trna synthetase
ACWT_RS37240	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACWT_RS37260	COG4166	transmembrane transport
ACWT_RS37265	COG3958	Transketolase
ACWT_RS37270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACWT_RS37275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACWT_RS37280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACWT_RS37295	COG0189	ligase activity
ACWT_RS37325	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACWT_RS37335	COG0515	serine threonine protein kinase
ACWT_RS37335	COG2815	serine threonine protein kinase
ACWT_RS37355	COG1733	regulation of RNA biosynthetic process
ACWT_RS37380	COG0673	inositol 2-dehydrogenase activity
ACWT_RS37400	COG0754	glutathionylspermidine amidase activity
ACWT_RS37430	COG3469	chitinase activity
ACWT_RS37445	COG0706	membrane insertase activity
ACWT_RS37455	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS37470	COG0740	serine-type endopeptidase activity
ACWT_RS37480	COG1834	amidinotransferase
ACWT_RS37485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACWT_RS37525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACWT_RS37530	COG2205	protein histidine kinase activity
ACWT_RS37535	COG0745	RESPONSE REGULATOR receiver
ACWT_RS37555	COG0567	Dehydrogenase, E1 component
ACWT_RS37555	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACWT_RS37565	COG0857	belongs to the CobB CobQ family
ACWT_RS37565	COG0280	phosphate acetyltransferase
ACWT_RS37570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACWT_RS37595	COG2172	sigma factor antagonist activity
ACWT_RS37600	COG2188	Transcriptional regulator
ACWT_RS37610	COG1597	lipid kinase activity
ACWT_RS37625	COG0175	sulfate reduction
ACWT_RS37640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACWT_RS37650	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ACWT_RS37660	COG1595	DNA-templated transcription, initiation
ACWT_RS37675	COG2135	peptidase activity
ACWT_RS37680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACWT_RS37685	COG1162	GTPase activity
ACWT_RS37690	COG0483	inositol monophosphate 1-phosphatase activity
ACWT_RS37765	COG1357	PFAM Pentapeptide repeats (8 copies)
ACWT_RS37805	COG0477	Major facilitator Superfamily
ACWT_RS37810	COG1396	sequence-specific DNA binding
ACWT_RS37810	COG3800	Transcriptional regulator
ACWT_RS37825	COG1615	UPF0182 protein
ACWT_RS37830	COG3480	Lon protease (S16) C-terminal proteolytic domain
ACWT_RS37855	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACWT_RS37890	COG2816	NAD+ diphosphatase activity
ACWT_RS37905	COG1959	2 iron, 2 sulfur cluster binding
ACWT_RS37915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACWT_RS37935	COG1278	Cold shock
ACWT_RS37950	COG0210	DNA helicase
ACWT_RS37950	COG0210	DNA helicase
ACWT_RS37955	COG1611	Belongs to the LOG family
ACWT_RS37960	COG1611	Belongs to the LOG family
ACWT_RS37970	COG2171	N-acyltransferase activity
ACWT_RS38020	COG4221	oxidoreductase activity
ACWT_RS38045	COG0456	acetyltransferase
ACWT_RS38060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACWT_RS38065	COG0823	Involved in the tonB-independent uptake of proteins
ACWT_RS38065	COG1506	peptidase
ACWT_RS38075	COG0312	modulator of DNA gyrase
ACWT_RS38085	COG1053	succinate dehydrogenase
ACWT_RS38140	COG1028	Short-chain dehydrogenase reductase Sdr
ACWT_RS38150	COG1960	acyl-CoA dehydrogenase activity
ACWT_RS38165	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACWT_RS38180	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS38250	COG0012	GTP binding
ACWT_RS38265	COG2169	Transcriptional regulator
ACWT_RS38265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACWT_RS38285	COG0525	valine-tRNA ligase activity
ACWT_RS38305	COG1322	Protein conserved in bacteria
ACWT_RS38310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACWT_RS38320	COG1570	exodeoxyribonuclease VII activity
ACWT_RS38325	COG1722	exodeoxyribonuclease VII activity
ACWT_RS38355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACWT_RS38360	COG0561	phosphatase activity
ACWT_RS38360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACWT_RS38365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACWT_RS38370	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ACWT_RS38375	COG1595	DNA-templated transcription, initiation
ACWT_RS38405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACWT_RS38435	COG1404	Belongs to the peptidase S8 family
ACWT_RS38440	COG0424	maF-like protein
ACWT_RS38445	COG4770	biotin carboxylase activity
ACWT_RS38495	COG1473	amidohydrolase
ACWT_RS38495	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACWT_RS38500	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACWT_RS38500	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACWT_RS38505	COG0515	serine threonine protein kinase
ACWT_RS38505	COG2815	serine threonine protein kinase
ACWT_RS38510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACWT_RS38525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACWT_RS38550	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS38575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACWT_RS38585	COG1012	belongs to the aldehyde dehydrogenase family
ACWT_RS38590	COG1012	belongs to the aldehyde dehydrogenase family
ACWT_RS38620	COG2018	Roadblock/LC7 domain
ACWT_RS38630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACWT_RS38655	COG1079	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS38660	COG4603	Belongs to the binding-protein-dependent transport system permease family
ACWT_RS38665	COG3845	ABC transporter
ACWT_RS38670	COG1744	ABC transporter substrate-binding protein PnrA-like
ACWT_RS38695	COG0180	Tryptophanyl-tRNA synthetase
ACWT_RS38700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACWT_RS38705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACWT_RS38730	COG1218	3'(2'),5'-bisphosphate nucleotidase
ACWT_RS38735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACWT_RS38740	COG0193	aminoacyl-tRNA hydrolase activity
ACWT_RS38755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACWT_RS38770	COG1309	transcriptional regulator
ACWT_RS38780	COG0488	(ABC) transporter
ACWT_RS38785	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACWT_RS38790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACWT_RS38795	COG0084	hydrolase, TatD family'
ACWT_RS38805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACWT_RS38850	COG4974	Belongs to the 'phage' integrase family
ACWT_RS38870	COG0303	'Molybdopterin
ACWT_RS38875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACWT_RS38930	COG2095	MarC family integral membrane protein
ACWT_RS38935	COG0613	PHP domain protein
ACWT_RS38955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACWT_RS38995	COG0384	phenazine biosynthesis protein PhzF
ACWT_RS39000	COG2239	Acts as a magnesium transporter
ACWT_RS39015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACWT_RS39020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACWT_RS39030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACWT_RS39045	COG1024	Enoyl-CoA hydratase
ACWT_RS39055	COG0519	Catalyzes the synthesis of GMP from XMP
ACWT_RS39070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACWT_RS39075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACWT_RS39075	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACWT_RS39080	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACWT_RS39085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACWT_RS39115	COG0113	porphobilinogen synthase activity
ACWT_RS39120	COG1587	Uroporphyrinogen-III synthase
ACWT_RS39120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACWT_RS39125	COG0181	hydroxymethylbilane synthase activity
ACWT_RS39130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACWT_RS39135	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ACWT_RS39150	COG0318	PFAM AMP-dependent synthetase and ligase
ACWT_RS39155	COG1595	DNA-templated transcription, initiation
ACWT_RS39185	COG0506	proline dehydrogenase activity
ACWT_RS39195	COG1082	Xylose isomerase domain protein TIM barrel
ACWT_RS39220	COG0588	phosphoglycerate mutase activity
ACWT_RS39245	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS39260	COG0745	RESPONSE REGULATOR receiver
ACWT_RS39275	COG5002	protein histidine kinase activity
ACWT_RS39290	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACWT_RS39295	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ACWT_RS39305	COG1256	bacterial-type flagellum assembly
ACWT_RS39305	COG4786	Flagellar basal body rod
ACWT_RS39325	COG1516	flagellar protein fliS
ACWT_RS39335	COG1815	bacterial-type flagellum-dependent cell motility
ACWT_RS39345	COG1677	Flagellar hook-basal body complex protein FliE
ACWT_RS39355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACWT_RS39365	COG1157	protein secretion by the type III secretion system
ACWT_RS39380	COG0741	lytic transglycosylase activity
ACWT_RS39380	COG0739	heme binding
ACWT_RS39380	COG1196	nuclear chromosome segregation
ACWT_RS39400	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACWT_RS39405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACWT_RS39415	COG1338	Plays a role in the flagellum-specific transport system
ACWT_RS39425	COG1776	CheC inhibitor of MCP methylation
ACWT_RS39425	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACWT_RS39430	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACWT_RS39440	COG1360	Flagellar Motor Protein
ACWT_RS39445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACWT_RS39470	COG0745	RESPONSE REGULATOR receiver
ACWT_RS39480	COG0745	RESPONSE REGULATOR receiver
ACWT_RS39490	COG2201	protein-glutamate methylesterase activity
ACWT_RS39505	COG0643	Histidine kinase
ACWT_RS39505	COG0784	Response regulator, receiver
ACWT_RS39505	COG2198	Histidine kinase
ACWT_RS39510	COG0745	RESPONSE REGULATOR receiver
ACWT_RS39515	COG2340	Cysteine-rich secretory protein family
ACWT_RS39520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACWT_RS39580	COG3246	L-lysine catabolic process to acetate
ACWT_RS39585	COG0354	folic acid binding
ACWT_RS39605	COG4044	May play a role in the intracellular transport of hydrophobic ligands
ACWT_RS39635	COG1595	DNA-templated transcription, initiation
ACWT_RS39665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACWT_RS39670	COG0581	inorganic phosphate transmembrane transporter activity
ACWT_RS39685	COG0456	acetyltransferase
ACWT_RS39690	COG0745	RESPONSE REGULATOR receiver
ACWT_RS39725	COG2339	peptidase activity
ACWT_RS39755	COG0459	protein refolding
ACWT_RS39770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACWT_RS39780	COG1131	(ABC) transporter
ACWT_RS39785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACWT_RS39800	COG1131	(ABC) transporter
ACWT_RS39805	COG1349	DNA-binding transcription factor activity
ACWT_RS39815	COG1940	carbohydrate kinase activity
ACWT_RS39825	COG1131	(ABC) transporter
ACWT_RS39840	COG2197	response regulator
ACWT_RS39895	COG3842	ATPase activity
ACWT_RS39925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACWT_RS39930	COG0215	cysteine-tRNA ligase activity
ACWT_RS39935	COG1404	Belongs to the peptidase S8 family
ACWT_RS39940	COG0114	fumarate hydratase activity
ACWT_RS39945	COG3903	Transcriptional regulator
ACWT_RS39945	COG3629	intracellular signal transduction
ACWT_RS39955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACWT_RS39955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACWT_RS39970	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ACWT_RS39980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACWT_RS39990	COG1940	carbohydrate kinase activity
ACWT_RS40010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACWT_RS40015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACWT_RS40040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACWT_RS40055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACWT_RS40060	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ACWT_RS40090	COG1194	a g-specific adenine glycosylase
ACWT_RS40125	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACWT_RS40130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACWT_RS40140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACWT_RS40150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACWT_RS40155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACWT_RS40170	COG0649	NAD binding
ACWT_RS40185	COG1174	glycine betaine transport
ACWT_RS40190	COG1174	glycine betaine transport
ACWT_RS40225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACWT_RS40260	COG0741	lytic transglycosylase activity
ACWT_RS40260	COG0739	heme binding
ACWT_RS40260	COG1196	nuclear chromosome segregation
ACWT_RS40290	COG0302	gtp cyclohydrolase
ACWT_RS40295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACWT_RS40300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACWT_RS40305	COG0037	tRNA processing
ACWT_RS40315	COG2027	D-alanyl-D-alanine carboxypeptidase
ACWT_RS40320	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACWT_RS40330	COG1674	ftsk spoiiie
ACWT_RS40350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACWT_RS40360	COG2843	Capsule synthesis protein
ACWT_RS40375	COG4770	biotin carboxylase activity
ACWT_RS40415	COG0003	Pfam Anion-transporting ATPase
ACWT_RS40425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACWT_RS40430	COG1610	YqeY-like protein
ACWT_RS40435	COG1408	metallophosphoesterase
ACWT_RS40450	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACWT_RS40470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACWT_RS40485	COG4608	Belongs to the ABC transporter superfamily
ACWT_RS40500	COG0747	negative chemotaxis
ACWT_RS40510	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACWT_RS40555	COG0813	purine-nucleoside phosphorylase activity
ACWT_RS40585	COG0287	Prephenate dehydrogenase
ACWT_RS40590	COG2318	DinB family
ACWT_RS40595	COG0235	Class ii aldolase
ACWT_RS40595	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACWT_RS40600	COG0501	Belongs to the peptidase M48B family
ACWT_RS40605	COG1796	DNA polymerase
ACWT_RS40605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACWT_RS40625	COG0642	Histidine kinase
ACWT_RS40630	COG2018	Roadblock/LC7 domain
ACWT_RS40680	COG3979	chitinase
ACWT_RS40740	COG0778	Nitroreductase
ACWT_RS40750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACWT_RS40770	COG2205	protein histidine kinase activity
ACWT_RS40790	COG1268	BioY protein
ACWT_RS40815	COG0667	Aldo Keto reductase
ACWT_RS40830	COG1131	(ABC) transporter
ACWT_RS40840	COG1595	DNA-templated transcription, initiation
ACWT_RS40860	COG0673	inositol 2-dehydrogenase activity
ACWT_RS40865	COG0243	molybdopterin cofactor binding
ACWT_RS40875	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACWT_RS40885	COG1435	thymidine kinase activity
ACWT_RS40895	COG0443	Heat shock 70 kDa protein
ACWT_RS40925	COG2268	Band 7 protein
ACWT_RS40945	COG3979	chitinase
ACWT_RS40950	COG2199	diguanylate cyclase activity
ACWT_RS40950	COG2200	EAL domain
ACWT_RS40970	COG0148	phosphopyruvate hydratase activity
ACWT_RS40975	COG0789	Transcriptional regulator
ACWT_RS41020	COG1366	Belongs to the anti-sigma-factor antagonist family
ACWT_RS41030	COG2801	Transposase and inactivated derivatives
ACWT_RS41035	COG2801	Transposase and inactivated derivatives
ACWT_RS41035	COG3415	Transposase
ACWT_RS41040	COG2801	Transposase and inactivated derivatives
ACWT_RS41135	COG1881	PFAM PEBP family protein
ACWT_RS41175	COG0789	Transcriptional regulator
ACWT_RS41180	COG3959	Transketolase, thiamine diphosphate binding domain
ACWT_RS41185	COG3958	Transketolase
ACWT_RS41215	COG0598	Magnesium transport protein CorA
ACWT_RS41220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACWT_RS41230	COG0371	Dehydrogenase
ACWT_RS41245	COG0438	transferase activity, transferring glycosyl groups
ACWT_RS41250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACWT_RS41265	COG3275	phosphorelay sensor kinase activity
ACWT_RS41275	COG0745	RESPONSE REGULATOR receiver
ACWT_RS41280	COG2205	protein histidine kinase activity
ACWT_RS41295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACWT_RS41330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACWT_RS41395	COG1764	response to oxidative stress
ACWT_RS41405	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACWT_RS41410	COG0561	phosphatase activity
ACWT_RS41415	COG0561	phosphatase activity
ACWT_RS41425	COG1834	amidinotransferase
ACWT_RS41430	COG1522	sequence-specific DNA binding
ACWT_RS41450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACWT_RS41470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACWT_RS41480	COG1408	metallophosphoesterase
ACWT_RS41525	COG0315	cyclic pyranopterin monophosphate synthase activity
ACWT_RS41525	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACWT_RS41530	COG0315	cyclic pyranopterin monophosphate synthase activity
ACWT_RS41535	COG2203	Gaf domain
ACWT_RS41535	COG5001	Diguanylate cyclase
ACWT_RS41535	COG4251	negative regulation of phosphorylation
ACWT_RS41535	COG3706	GGDEF domain
ACWT_RS41565	COG0359	binds to the 23S rRNA
ACWT_RS41570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACWT_RS41575	COG0629	single-stranded DNA binding
ACWT_RS41580	COG0360	Binds together with S18 to 16S ribosomal RNA
ACWT_RS41605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACWT_RS41615	COG1695	Transcriptional regulator
ACWT_RS41620	COG1260	myo-inositol-1-phosphate synthase
ACWT_RS41680	COG0617	tRNA 3'-terminal CCA addition
ACWT_RS41695	COG0515	serine threonine protein kinase
ACWT_RS41695	COG2815	serine threonine protein kinase
ACWT_RS41700	COG1595	DNA-templated transcription, initiation
ACWT_RS41715	COG3118	belongs to the thioredoxin family
ACWT_RS41720	COG3409	Peptidoglycan-binding domain 1 protein
ACWT_RS41720	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACWT_RS41730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACWT_RS41735	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACWT_RS41760	COG1192	Involved in chromosome partitioning
ACWT_RS41765	COG0357	Ribosomal RNA small subunit methyltransferase G
ACWT_RS41775	COG0706	membrane insertase activity
ACWT_RS41780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACWT_RS41785	COG0594	ribonuclease P activity
ACWT_RS41790	COG0230	Belongs to the bacterial ribosomal protein bL34 family