locus-tag	class	description
ACTEI_RS00010	COG0592	DNA-directed DNA polymerase activity
ACTEI_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACTEI_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACTEI_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ACTEI_RS00040	COG0187	DNA topoisomerase II activity
ACTEI_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACTEI_RS00050	COG3266	domain, Protein
ACTEI_RS00080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACTEI_RS00095	COG0442	prolyl-tRNA aminoacylation
ACTEI_RS00115	COG0439	Biotin carboxylase
ACTEI_RS00120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACTEI_RS00135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACTEI_RS00140	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS00145	COG1846	Transcriptional regulator
ACTEI_RS00150	COG2353	YceI-like domain
ACTEI_RS00190	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ACTEI_RS00200	COG1716	ATPase activity
ACTEI_RS00200	COG1716	ATPase activity
ACTEI_RS00205	COG1716	ATPase activity
ACTEI_RS00220	COG0768	penicillin binding
ACTEI_RS00225	COG0515	serine threonine protein kinase
ACTEI_RS00230	COG0515	serine threonine protein kinase
ACTEI_RS00230	COG2815	serine threonine protein kinase
ACTEI_RS00265	COG2181	nitrate reductase activity
ACTEI_RS00265	COG0247	lactate metabolic process
ACTEI_RS00310	COG0717	Belongs to the dCTP deaminase family
ACTEI_RS00330	COG2770	Histidine kinase
ACTEI_RS00330	COG2208	phosphoserine phosphatase activity
ACTEI_RS00335	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS00360	COG1984	allophanate hydrolase subunit 2
ACTEI_RS00380	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACTEI_RS00385	COG0022	dehydrogenase e1 component
ACTEI_RS00420	COG0443	Heat shock 70 kDa protein
ACTEI_RS00425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACTEI_RS00430	COG0484	heat shock protein binding
ACTEI_RS00435	COG0789	Transcriptional regulator
ACTEI_RS00445	COG0475	glutathione-regulated potassium exporter activity
ACTEI_RS00455	COG2814	Major facilitator Superfamily
ACTEI_RS00460	COG0542	response to heat
ACTEI_RS00475	COG0640	Transcriptional regulator
ACTEI_RS00480	COG0235	Class ii aldolase
ACTEI_RS00485	COG0586	Pfam SNARE associated Golgi protein
ACTEI_RS00490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACTEI_RS00495	COG2890	protein-(glutamine-N5) methyltransferase activity
ACTEI_RS00505	COG1316	TRANSCRIPTIONal
ACTEI_RS00510	COG3293	Transposase
ACTEI_RS00565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACTEI_RS00570	COG0151	Belongs to the GarS family
ACTEI_RS00590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACTEI_RS00600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACTEI_RS00605	COG0047	phosphoribosylformylglycinamidine synthase activity
ACTEI_RS00610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACTEI_RS00630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACTEI_RS00635	COG0641	radical SAM
ACTEI_RS00675	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
ACTEI_RS00690	COG2197	response regulator
ACTEI_RS00695	COG4585	Histidine kinase
ACTEI_RS00715	COG2050	protein possibly involved in aromatic compounds catabolism
ACTEI_RS00750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ACTEI_RS00760	COG0142	geranyltranstransferase activity
ACTEI_RS00775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACTEI_RS00840	COG1970	mechanosensitive ion channel activity
ACTEI_RS00850	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS00855	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS00860	COG2172	sigma factor antagonist activity
ACTEI_RS00875	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS00895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACTEI_RS00900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACTEI_RS00910	COG0784	Response regulator, receiver
ACTEI_RS00910	COG2205	protein histidine kinase activity
ACTEI_RS00915	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS00940	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS00945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACTEI_RS00950	COG0406	alpha-ribazole phosphatase activity
ACTEI_RS00955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACTEI_RS00965	COG1333	cytochrome c biogenesis protein
ACTEI_RS00970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACTEI_RS00980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACTEI_RS00990	COG0163	prenyltransferase activity
ACTEI_RS01005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACTEI_RS01020	COG0513	Belongs to the DEAD box helicase family
ACTEI_RS01030	COG0791	NLP P60 protein
ACTEI_RS01030	COG3883	PFAM NLP P60 protein
ACTEI_RS01035	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACTEI_RS01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACTEI_RS01060	COG1120	ATPase activity
ACTEI_RS01080	COG3973	AAA domain
ACTEI_RS01085	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACTEI_RS01095	COG0667	Aldo Keto reductase
ACTEI_RS01100	COG4279	zinc finger
ACTEI_RS01105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACTEI_RS01120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACTEI_RS01150	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACTEI_RS01155	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACTEI_RS01160	COG0649	NAD binding
ACTEI_RS01170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACTEI_RS01175	COG1034	ATP synthesis coupled electron transport
ACTEI_RS01180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACTEI_RS01185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACTEI_RS01195	COG0713	ATP synthesis coupled electron transport
ACTEI_RS01210	COG1007	ATP synthesis coupled electron transport
ACTEI_RS01215	COG0142	geranyltranstransferase activity
ACTEI_RS01240	COG1950	PFAM Membrane protein of
ACTEI_RS01275	COG0596	Alpha beta hydrolase
ACTEI_RS01290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACTEI_RS01370	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS01385	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACTEI_RS01400	COG1754	DNA topoisomerase type I activity
ACTEI_RS01400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACTEI_RS01410	COG1309	transcriptional regulator
ACTEI_RS01435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACTEI_RS01465	COG1774	PSP1 C-terminal conserved region
ACTEI_RS01490	COG4974	Belongs to the 'phage' integrase family
ACTEI_RS01505	COG1051	belongs to the nudix hydrolase family
ACTEI_RS01540	COG0477	Major facilitator Superfamily
ACTEI_RS01555	COG0738	Major facilitator superfamily
ACTEI_RS01560	COG0644	oxidoreductase
ACTEI_RS01600	COG0583	DNA-binding transcription factor activity
ACTEI_RS01605	COG0702	epimerase
ACTEI_RS01625	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ACTEI_RS01635	COG3285	dna ligase
ACTEI_RS01635	COG1793	dna ligase
ACTEI_RS01655	COG1061	Type III restriction enzyme res subunit
ACTEI_RS01670	COG0546	phosphoglycolate phosphatase activity
ACTEI_RS01675	COG1278	Cold shock
ACTEI_RS01680	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACTEI_RS01695	COG2723	6-phospho-beta-galactosidase activity
ACTEI_RS01710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACTEI_RS01730	COG2252	PERMEase
ACTEI_RS01735	COG1846	Transcriptional regulator
ACTEI_RS01740	COG2814	Major facilitator Superfamily
ACTEI_RS01750	COG2130	NADP-dependent
ACTEI_RS01755	COG0789	Transcriptional regulator
ACTEI_RS01760	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ACTEI_RS01770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACTEI_RS01780	COG0259	pyridoxamine-phosphate oxidase activity
ACTEI_RS01790	COG2017	converts alpha-aldose to the beta-anomer
ACTEI_RS01820	COG3842	ATPase activity
ACTEI_RS01855	COG1388	LysM domain
ACTEI_RS01855	COG1134	teichoic acid transport
ACTEI_RS01865	COG1309	transcriptional regulator
ACTEI_RS01880	COG0477	Major facilitator Superfamily
ACTEI_RS01920	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS01925	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS01925	COG3321	synthase
ACTEI_RS01925	COG0604	alcohol dehydrogenase
ACTEI_RS01935	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
ACTEI_RS01950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACTEI_RS01955	COG1086	Polysaccharide biosynthesis protein
ACTEI_RS01995	COG2197	response regulator
ACTEI_RS02005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACTEI_RS02010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACTEI_RS02030	COG2089	acid synthase
ACTEI_RS02040	COG1216	Glycosyl transferase, family 2
ACTEI_RS02045	COG3300	MHYT domain
ACTEI_RS02045	COG5001	Diguanylate cyclase
ACTEI_RS02075	COG2119	membrane
ACTEI_RS02080	COG0596	Alpha beta hydrolase
ACTEI_RS02105	COG0586	Pfam SNARE associated Golgi protein
ACTEI_RS02110	COG2814	Major facilitator Superfamily
ACTEI_RS02155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACTEI_RS02165	COG1309	transcriptional regulator
ACTEI_RS02170	COG1131	(ABC) transporter
ACTEI_RS02175	COG3559	Exporter of polyketide antibiotics
ACTEI_RS02185	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACTEI_RS02195	COG3795	YCII-related domain
ACTEI_RS02205	COG5278	phosphoserine phosphatase activity
ACTEI_RS02205	COG0840	transmembrane signaling receptor activity
ACTEI_RS02210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACTEI_RS02225	COG1335	isochorismatase
ACTEI_RS02260	COG2971	BadF BadG BcrA BcrD
ACTEI_RS02265	COG1737	Transcriptional regulator
ACTEI_RS02270	COG4821	SIS domain
ACTEI_RS02275	COG1653	transport
ACTEI_RS02280	COG1175	transmembrane transport
ACTEI_RS02285	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS02310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACTEI_RS02315	COG2188	Transcriptional regulator
ACTEI_RS02320	COG0488	(ABC) transporter
ACTEI_RS02385	COG1674	ftsk spoiiie
ACTEI_RS02400	COG2188	Transcriptional regulator
ACTEI_RS02420	COG0483	inositol monophosphate 1-phosphatase activity
ACTEI_RS02430	COG0657	acetylesterase activity
ACTEI_RS02440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACTEI_RS02440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACTEI_RS02445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACTEI_RS02460	COG0737	Belongs to the 5'-nucleotidase family
ACTEI_RS02465	COG0583	DNA-binding transcription factor activity
ACTEI_RS02475	COG1388	LysM domain
ACTEI_RS02480	COG3268	Saccharopine dehydrogenase
ACTEI_RS02510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACTEI_RS02515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACTEI_RS02520	COG2205	protein histidine kinase activity
ACTEI_RS02525	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS02535	COG1193	negative regulation of DNA recombination
ACTEI_RS02550	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS02555	COG4251	negative regulation of phosphorylation
ACTEI_RS02560	COG0784	Response regulator, receiver
ACTEI_RS02565	COG0483	inositol monophosphate 1-phosphatase activity
ACTEI_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS02585	COG2815	serine threonine protein kinase
ACTEI_RS02585	COG0515	serine threonine protein kinase
ACTEI_RS02590	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS02600	COG0514	ATP-dependent DNA helicase (RecQ)
ACTEI_RS02610	COG1937	Protein conserved in bacteria
ACTEI_RS02615	COG2608	mercury ion transmembrane transporter activity
ACTEI_RS02640	COG0513	Belongs to the DEAD box helicase family
ACTEI_RS02690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACTEI_RS02695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACTEI_RS02725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACTEI_RS02740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACTEI_RS02745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACTEI_RS02755	COG0713	ATP synthesis coupled electron transport
ACTEI_RS02760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACTEI_RS02765	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACTEI_RS02770	COG1007	ATP synthesis coupled electron transport
ACTEI_RS02785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS02800	COG0501	Belongs to the peptidase M48B family
ACTEI_RS02855	COG5001	Diguanylate cyclase
ACTEI_RS02855	COG3300	MHYT domain
ACTEI_RS02870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACTEI_RS02875	COG2030	dehydratase
ACTEI_RS02900	COG0081	regulation of translation
ACTEI_RS02930	COG0085	RNA polymerase activity
ACTEI_RS02935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACTEI_RS02950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACTEI_RS02955	COG0049	tRNA binding
ACTEI_RS02960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACTEI_RS02965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACTEI_RS02970	COG0051	transcription antitermination factor activity, RNA binding
ACTEI_RS02975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACTEI_RS02980	COG0088	Forms part of the polypeptide exit tunnel
ACTEI_RS02990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACTEI_RS02995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACTEI_RS03000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACTEI_RS03005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACTEI_RS03010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACTEI_RS03015	COG0255	Belongs to the universal ribosomal protein uL29 family
ACTEI_RS03020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACTEI_RS03025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACTEI_RS03030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACTEI_RS03035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACTEI_RS03040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACTEI_RS03045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACTEI_RS03050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACTEI_RS03055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACTEI_RS03060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACTEI_RS03065	COG1841	ribosomal large subunit assembly
ACTEI_RS03070	COG0200	Binds to the 23S rRNA
ACTEI_RS03080	COG0563	adenylate kinase activity
ACTEI_RS03095	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACTEI_RS03100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACTEI_RS03105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACTEI_RS03110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACTEI_RS03115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACTEI_RS03125	COG0203	ribosomal protein L17
ACTEI_RS03130	COG0101	tRNA pseudouridine synthase activity
ACTEI_RS03140	COG2813	Specifically methylates the guanine in position
ACTEI_RS03145	COG0488	(ABC) transporter
ACTEI_RS03150	COG0352	thiamine-phosphate diphosphorylase activity
ACTEI_RS03155	COG2022	thiamine diphosphate biosynthetic process
ACTEI_RS03155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACTEI_RS03165	COG2022	thiamine diphosphate biosynthetic process
ACTEI_RS03170	COG0352	thiamine-phosphate diphosphorylase activity
ACTEI_RS03175	COG0351	phosphomethylpyrimidine kinase
ACTEI_RS03180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACTEI_RS03210	COG2018	Roadblock/LC7 domain
ACTEI_RS03230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACTEI_RS03235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACTEI_RS03240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACTEI_RS03255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACTEI_RS03270	COG0736	holo-[acyl-carrier-protein] synthase activity
ACTEI_RS03280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACTEI_RS03290	COG0802	atpase or kinase
ACTEI_RS03295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACTEI_RS03310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACTEI_RS03320	COG1132	(ABC) transporter
ACTEI_RS03325	COG1132	(ABC) transporter
ACTEI_RS03330	COG0459	protein refolding
ACTEI_RS03335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACTEI_RS03345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACTEI_RS03360	COG4214	carbohydrate transport
ACTEI_RS03365	COG1940	carbohydrate kinase activity
ACTEI_RS03385	COG2197	response regulator
ACTEI_RS03400	COG0516	GMP reductase activity
ACTEI_RS03410	COG1316	TRANSCRIPTIONal
ACTEI_RS03420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACTEI_RS03420	COG0519	Catalyzes the synthesis of GMP from XMP
ACTEI_RS03425	COG1051	belongs to the nudix hydrolase family
ACTEI_RS03435	COG1183	phosphatidylcholine synthase activity
ACTEI_RS03440	COG0688	phosphatidylethanolamine metabolic process
ACTEI_RS03455	COG4585	Histidine kinase
ACTEI_RS03460	COG2197	response regulator
ACTEI_RS03470	COG0601	transmembrane transport
ACTEI_RS03475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACTEI_RS03480	COG0444	Belongs to the ABC transporter superfamily
ACTEI_RS03485	COG4608	Belongs to the ABC transporter superfamily
ACTEI_RS03490	COG1605	Chorismate mutase
ACTEI_RS03495	COG1525	nuclease
ACTEI_RS03495	COG0737	Belongs to the 5'-nucleotidase family
ACTEI_RS03495	COG4085	toxin activity
ACTEI_RS03505	COG1196	nuclear chromosome segregation
ACTEI_RS03505	COG0741	lytic transglycosylase activity
ACTEI_RS03505	COG0739	heme binding
ACTEI_RS03510	COG4942	peptidase
ACTEI_RS03515	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACTEI_RS03520	COG0045	succinate-CoA ligase (ADP-forming) activity
ACTEI_RS03540	COG0138	bifunctional purine biosynthesis protein purh
ACTEI_RS03545	COG0538	isocitrate dehydrogenase activity
ACTEI_RS03550	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS03550	COG1454	alcohol dehydrogenase
ACTEI_RS03560	COG1349	DNA-binding transcription factor activity
ACTEI_RS03650	COG0529	Catalyzes the synthesis of activated sulfate
ACTEI_RS03670	COG1131	(ABC) transporter
ACTEI_RS03680	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACTEI_RS03730	COG0148	phosphopyruvate hydratase activity
ACTEI_RS03745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACTEI_RS03780	COG0714	Associated with various cellular activities
ACTEI_RS03795	COG1252	NADH dehydrogenase
ACTEI_RS03820	COG0183	Belongs to the thiolase family
ACTEI_RS03845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACTEI_RS03860	COG1234	tRNA 3'-trailer cleavage
ACTEI_RS03865	COG2326	polyphosphate kinase activity
ACTEI_RS03935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACTEI_RS03940	COG0537	adenosine 5'-monophosphoramidase activity
ACTEI_RS03955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACTEI_RS03960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACTEI_RS03970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACTEI_RS03985	COG1331	Highly conserved protein containing a thioredoxin domain
ACTEI_RS04065	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS04120	COG1132	(ABC) transporter
ACTEI_RS04160	COG1609	Transcriptional regulator
ACTEI_RS04185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACTEI_RS04195	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS04210	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ACTEI_RS04210	COG0778	Nitroreductase
ACTEI_RS04215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACTEI_RS04225	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACTEI_RS04255	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS04265	COG1515	deoxyribonuclease V activity
ACTEI_RS04270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACTEI_RS04275	COG2835	tetraacyldisaccharide 4'-kinase activity
ACTEI_RS04285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACTEI_RS04290	COG1482	cell wall glycoprotein biosynthetic process
ACTEI_RS04305	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS04310	COG5002	protein histidine kinase activity
ACTEI_RS04325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACTEI_RS04330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACTEI_RS04335	COG0653	protein targeting
ACTEI_RS04360	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS04370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACTEI_RS04375	COG2884	Cell division ATP-binding protein ftsE
ACTEI_RS04380	COG2177	Part of the ABC transporter FtsEX involved in
ACTEI_RS04385	COG0739	heme binding
ACTEI_RS04390	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACTEI_RS04430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACTEI_RS04435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACTEI_RS04465	COG0534	Mate efflux family protein
ACTEI_RS04470	COG3629	intracellular signal transduction
ACTEI_RS04470	COG3903	Transcriptional regulator
ACTEI_RS04515	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACTEI_RS04525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS04545	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACTEI_RS04555	COG1459	type II secretion system
ACTEI_RS04565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACTEI_RS04580	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS04655	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACTEI_RS04660	COG2200	EAL domain
ACTEI_RS04660	COG2199	diguanylate cyclase activity
ACTEI_RS04660	COG2203	Gaf domain
ACTEI_RS04685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS04690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACTEI_RS04710	COG1335	isochorismatase
ACTEI_RS04715	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACTEI_RS04750	COG1234	tRNA 3'-trailer cleavage
ACTEI_RS04755	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS04760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACTEI_RS04765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACTEI_RS04780	COG2986	histidine ammonia-lyase
ACTEI_RS04785	COG1228	amidohydrolase
ACTEI_RS04790	COG0402	S-adenosylhomocysteine deaminase activity
ACTEI_RS04795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACTEI_RS04800	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACTEI_RS04960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACTEI_RS05010	COG3217	Mosc domain protein beta barrel domain protein
ACTEI_RS05010	COG0633	Ferredoxin
ACTEI_RS05060	COG2372	response to copper ion
ACTEI_RS05060	COG1276	copper resistance
ACTEI_RS05070	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACTEI_RS05090	COG5297	Belongs to the glycosyl hydrolase family 6
ACTEI_RS05120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS05140	COG1376	ErfK ybiS ycfS ynhG family protein
ACTEI_RS05145	COG1376	ErfK ybiS ycfS ynhG family protein
ACTEI_RS05155	COG3012	SEC-C Motif Domain Protein
ACTEI_RS05170	COG4733	cellulase activity
ACTEI_RS05175	COG0431	NADPH-dependent FMN reductase
ACTEI_RS05180	COG2124	cytochrome p450
ACTEI_RS05190	COG2255	four-way junction helicase activity
ACTEI_RS05220	COG3706	GGDEF domain
ACTEI_RS05270	COG1280	lysine exporter protein (LysE YggA)
ACTEI_RS05280	COG1846	Transcriptional regulator
ACTEI_RS05280	COG1940	carbohydrate kinase activity
ACTEI_RS05290	COG4209	transmembrane transport
ACTEI_RS05295	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS05350	COG0277	FAD linked oxidase domain protein
ACTEI_RS05360	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS05390	COG1216	Glycosyl transferase, family 2
ACTEI_RS05405	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS05435	COG2378	regulation of single-species biofilm formation
ACTEI_RS05480	COG1609	Transcriptional regulator
ACTEI_RS05490	COG2706	6-phosphogluconolactonase activity
ACTEI_RS05500	COG1940	carbohydrate kinase activity
ACTEI_RS05505	COG2115	Belongs to the xylose isomerase family
ACTEI_RS05510	COG1070	Carbohydrate kinase
ACTEI_RS05530	COG0366	Alpha amylase catalytic
ACTEI_RS05535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACTEI_RS05560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACTEI_RS05565	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS05625	COG2264	protein methyltransferase activity
ACTEI_RS05635	COG2197	response regulator
ACTEI_RS05645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACTEI_RS05675	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACTEI_RS05680	COG1492	cobalamin metabolic process
ACTEI_RS05685	COG0501	Belongs to the peptidase M48B family
ACTEI_RS05705	COG1793	dna ligase
ACTEI_RS05720	COG1797	cobyrinic acid a,c-diamide synthase activity
ACTEI_RS05740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACTEI_RS05750	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACTEI_RS05755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACTEI_RS05755	COG1648	precorrin-2 dehydrogenase activity
ACTEI_RS05805	COG0668	transmembrane transport
ACTEI_RS05830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACTEI_RS05845	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACTEI_RS05865	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACTEI_RS05875	COG4552	Acetyltransferase involved in intracellular survival and related
ACTEI_RS05885	COG0463	Glycosyl transferase, family 2
ACTEI_RS05895	COG0640	Transcriptional regulator
ACTEI_RS05915	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS05975	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ACTEI_RS05995	COG2188	Transcriptional regulator
ACTEI_RS06035	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACTEI_RS06040	COG0740	serine-type endopeptidase activity
ACTEI_RS06045	COG0740	serine-type endopeptidase activity
ACTEI_RS06050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACTEI_RS06090	COG0525	valine-tRNA ligase activity
ACTEI_RS06095	COG0285	dihydrofolate synthase activity
ACTEI_RS06110	COG0105	UTP biosynthetic process
ACTEI_RS06120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACTEI_RS06135	COG0596	Alpha beta hydrolase
ACTEI_RS06140	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS06140	COG2172	sigma factor antagonist activity
ACTEI_RS06140	COG2208	phosphoserine phosphatase activity
ACTEI_RS06155	COG1530	ribonuclease E activity
ACTEI_RS06165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACTEI_RS06170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACTEI_RS06175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACTEI_RS06185	COG0180	Tryptophanyl-tRNA synthetase
ACTEI_RS06200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACTEI_RS06210	COG0406	alpha-ribazole phosphatase activity
ACTEI_RS06220	COG1307	EDD domain protein, DegV family
ACTEI_RS06230	COG2890	protein-(glutamine-N5) methyltransferase activity
ACTEI_RS06235	COG1596	polysaccharide export
ACTEI_RS06235	COG1555	photosystem II stabilization
ACTEI_RS06240	COG0658	competence protein
ACTEI_RS06240	COG2333	competence protein COMEC
ACTEI_RS06265	COG0268	Binds directly to 16S ribosomal RNA
ACTEI_RS06285	COG0481	GTPase activity
ACTEI_RS06290	COG2261	transglycosylase associated protein
ACTEI_RS06315	COG1420	regulation of RNA biosynthetic process
ACTEI_RS06320	COG0484	heat shock protein binding
ACTEI_RS06350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACTEI_RS06365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACTEI_RS06380	COG1381	Involved in DNA repair and RecF pathway recombination
ACTEI_RS06385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACTEI_RS06400	COG0667	Aldo Keto reductase
ACTEI_RS06440	COG4172	Belongs to the ABC transporter superfamily
ACTEI_RS06450	COG0596	Alpha beta hydrolase
ACTEI_RS06475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACTEI_RS06480	COG1121	(ABC) transporter
ACTEI_RS06485	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACTEI_RS06485	COG3443	Belongs to the bacterial solute-binding protein 9 family
ACTEI_RS06505	COG0423	glycine-tRNA ligase activity
ACTEI_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS06535	COG2018	Roadblock/LC7 domain
ACTEI_RS06560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACTEI_RS06575	COG1131	(ABC) transporter
ACTEI_RS06590	COG1295	ribonuclease BN
ACTEI_RS06810	COG2124	cytochrome p450
ACTEI_RS06835	COG1609	Transcriptional regulator
ACTEI_RS06840	COG2721	sulfolactate sulfo-lyase activity
ACTEI_RS06915	COG0018	arginyl-trna synthetase
ACTEI_RS06920	COG0737	Belongs to the 5'-nucleotidase family
ACTEI_RS06930	COG0515	serine threonine protein kinase
ACTEI_RS06965	COG3973	AAA domain
ACTEI_RS07005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACTEI_RS07010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACTEI_RS07040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACTEI_RS07050	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACTEI_RS07055	COG0432	Pfam Uncharacterised protein family UPF0047
ACTEI_RS07115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACTEI_RS07150	COG0730	response to heat
ACTEI_RS07160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACTEI_RS07165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACTEI_RS07175	COG2226	methyltransferase
ACTEI_RS07200	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ACTEI_RS07205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACTEI_RS07210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACTEI_RS07210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACTEI_RS07215	COG0174	glutamine synthetase
ACTEI_RS07220	COG3766	membrane
ACTEI_RS07240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACTEI_RS07245	COG1846	Transcriptional regulator
ACTEI_RS07330	COG1674	ftsk spoiiie
ACTEI_RS07365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACTEI_RS07370	COG0017	Asparaginyl-tRNA synthetase
ACTEI_RS07380	COG0321	lipoyl(octanoyl) transferase activity
ACTEI_RS07395	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACTEI_RS07400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACTEI_RS07410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACTEI_RS07415	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACTEI_RS07420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ACTEI_RS07435	COG1994	Peptidase M50
ACTEI_RS07440	COG0667	Aldo Keto reductase
ACTEI_RS07505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACTEI_RS07515	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACTEI_RS07530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACTEI_RS07535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACTEI_RS07540	COG1929	Belongs to the glycerate kinase type-1 family
ACTEI_RS07550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACTEI_RS07560	COG0425	Belongs to the sulfur carrier protein TusA family
ACTEI_RS07565	COG1104	cysteine desulfurase activity
ACTEI_RS07570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACTEI_RS07585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACTEI_RS07605	COG2010	Cytochrome c
ACTEI_RS07630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACTEI_RS07640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACTEI_RS07655	COG0501	Belongs to the peptidase M48B family
ACTEI_RS07660	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS07680	COG2197	response regulator
ACTEI_RS07700	COG1940	carbohydrate kinase activity
ACTEI_RS07710	COG2072	flavoprotein involved in K transport
ACTEI_RS07770	COG0205	6-phosphofructokinase activity
ACTEI_RS07775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACTEI_RS07785	COG0386	Belongs to the glutathione peroxidase family
ACTEI_RS07795	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACTEI_RS07815	COG0504	CTP synthase activity
ACTEI_RS07820	COG0583	DNA-binding transcription factor activity
ACTEI_RS07825	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACTEI_RS07830	COG2815	serine threonine protein kinase
ACTEI_RS07830	COG0515	serine threonine protein kinase
ACTEI_RS07855	COG0142	geranyltranstransferase activity
ACTEI_RS07935	COG1309	transcriptional regulator
ACTEI_RS07950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACTEI_RS07955	COG1053	succinate dehydrogenase
ACTEI_RS07965	COG0583	DNA-binding transcription factor activity
ACTEI_RS07970	COG2226	methyltransferase
ACTEI_RS08050	COG0587	DNA-directed DNA polymerase activity
ACTEI_RS08095	COG0714	Associated with various cellular activities
ACTEI_RS08100	COG0495	leucyl-tRNA aminoacylation
ACTEI_RS08110	COG3442	glutamine amidotransferase
ACTEI_RS08125	COG2001	Belongs to the MraZ family
ACTEI_RS08130	COG0275	rRNA processing
ACTEI_RS08140	COG0768	penicillin binding
ACTEI_RS08145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACTEI_RS08150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACTEI_RS08155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACTEI_RS08165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACTEI_RS08170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACTEI_RS08175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACTEI_RS08180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACTEI_RS08185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACTEI_RS08190	COG1799	cell septum assembly
ACTEI_RS08200	COG3599	regulation of cell shape
ACTEI_RS08220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACTEI_RS08240	COG0587	DNA-directed DNA polymerase activity
ACTEI_RS08250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACTEI_RS08255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACTEI_RS08260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACTEI_RS08265	COG0131	Imidazoleglycerol-phosphate dehydratase
ACTEI_RS08270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACTEI_RS08280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACTEI_RS08285	COG0107	imidazoleglycerol-phosphate synthase activity
ACTEI_RS08300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACTEI_RS08315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACTEI_RS08330	COG0531	amino acid
ACTEI_RS08340	COG1132	(ABC) transporter
ACTEI_RS08345	COG1132	(ABC) transporter
ACTEI_RS08350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACTEI_RS08365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACTEI_RS08390	COG0133	tryptophan synthase activity
ACTEI_RS08395	COG0159	tryptophan synthase activity
ACTEI_RS08400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACTEI_RS08405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS08420	COG0069	glutamate synthase activity
ACTEI_RS08420	COG0070	glutamate synthase
ACTEI_RS08420	COG0067	glutamate synthase
ACTEI_RS08480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACTEI_RS08485	COG0765	amino acid transport
ACTEI_RS08490	COG1126	abc transporter atp-binding protein
ACTEI_RS08515	COG2226	methyltransferase
ACTEI_RS08520	COG0539	negative regulation of cytoplasmic translation
ACTEI_RS08525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACTEI_RS08525	COG0237	dephospho-CoA kinase activity
ACTEI_RS08535	COG2329	Antibiotic biosynthesis monooxygenase
ACTEI_RS08550	COG1217	gtp-binding protein TYPA
ACTEI_RS08555	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACTEI_RS08560	COG0740	serine-type endopeptidase activity
ACTEI_RS08575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACTEI_RS08585	COG1162	GTPase activity
ACTEI_RS08595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACTEI_RS08605	COG0322	excinuclease ABC activity
ACTEI_RS08610	COG1660	Displays ATPase and GTPase activities
ACTEI_RS08620	COG1481	regulation of sporulation
ACTEI_RS08625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACTEI_RS08630	COG0126	phosphoglycerate kinase activity
ACTEI_RS08635	COG0149	triose-phosphate isomerase activity
ACTEI_RS08640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACTEI_RS08660	COG0363	glucosamine-6-phosphate deaminase activity
ACTEI_RS08675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACTEI_RS08685	COG0109	protoheme IX farnesyltransferase activity
ACTEI_RS08725	COG0396	ATPase activity
ACTEI_RS08730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACTEI_RS08735	COG0822	iron-sulfur transferase activity
ACTEI_RS08740	COG2151	metal-sulfur cluster biosynthetic enzyme
ACTEI_RS08785	COG2321	neutral zinc metallopeptidase
ACTEI_RS08790	COG0488	(ABC) transporter
ACTEI_RS08800	COG1024	Enoyl-CoA hydratase
ACTEI_RS08805	COG1132	(ABC) transporter
ACTEI_RS08815	COG3663	DNA glycosylase
ACTEI_RS08825	COG1309	transcriptional regulator
ACTEI_RS08850	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACTEI_RS08875	COG0006	proline dipeptidase activity
ACTEI_RS08910	COG0714	Associated with various cellular activities
ACTEI_RS08925	COG2197	response regulator
ACTEI_RS08930	COG3850	Histidine kinase
ACTEI_RS08935	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS08940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACTEI_RS08945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACTEI_RS09030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACTEI_RS09045	COG1365	unkown
ACTEI_RS09050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACTEI_RS09065	COG2182	Extracellular solute-binding protein
ACTEI_RS09070	COG1175	transmembrane transport
ACTEI_RS09075	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS09080	COG1653	transport
ACTEI_RS09085	COG1175	transmembrane transport
ACTEI_RS09090	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS09095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACTEI_RS09095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACTEI_RS09105	COG3265	gluconokinase activity
ACTEI_RS09120	COG4585	Histidine kinase
ACTEI_RS09125	COG2197	response regulator
ACTEI_RS09185	COG3304	Inner membrane component domain
ACTEI_RS09195	COG1595	DNA-templated transcription, initiation
ACTEI_RS09205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACTEI_RS09210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACTEI_RS09220	COG1309	transcriptional regulator
ACTEI_RS09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACTEI_RS09255	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS09265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACTEI_RS09270	COG0515	serine threonine protein kinase
ACTEI_RS09270	COG2815	serine threonine protein kinase
ACTEI_RS09280	COG1253	flavin adenine dinucleotide binding
ACTEI_RS09285	COG0840	transmembrane signaling receptor activity
ACTEI_RS09335	COG1175	transmembrane transport
ACTEI_RS09350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACTEI_RS09350	COG1017	nitric oxide dioxygenase activity
ACTEI_RS09355	COG1959	2 iron, 2 sulfur cluster binding
ACTEI_RS09360	COG2205	protein histidine kinase activity
ACTEI_RS09365	COG2205	protein histidine kinase activity
ACTEI_RS09380	COG2205	protein histidine kinase activity
ACTEI_RS09390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACTEI_RS09400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACTEI_RS09405	COG3387	PFAM Glycoside hydrolase 15-related
ACTEI_RS09410	COG0667	Aldo Keto reductase
ACTEI_RS09415	COG2072	flavoprotein involved in K transport
ACTEI_RS09420	COG3293	Transposase
ACTEI_RS09430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACTEI_RS09440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACTEI_RS09450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACTEI_RS09490	COG1846	Transcriptional regulator
ACTEI_RS09525	COG1216	Glycosyl transferase, family 2
ACTEI_RS09560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACTEI_RS09575	COG1388	LysM domain
ACTEI_RS09575	COG1705	Flagellar rod assembly protein muramidase FlgJ
ACTEI_RS09615	COG0628	permease
ACTEI_RS09640	COG0657	acetylesterase activity
ACTEI_RS09740	COG2271	Major facilitator Superfamily
ACTEI_RS09745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ACTEI_RS09745	COG3321	synthase
ACTEI_RS09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACTEI_RS09765	COG0531	amino acid
ACTEI_RS09790	COG0367	asparagine synthase
ACTEI_RS09805	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACTEI_RS09810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACTEI_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS09870	COG0243	molybdopterin cofactor binding
ACTEI_RS09890	COG0439	Biotin carboxylase
ACTEI_RS09940	COG1070	Carbohydrate kinase
ACTEI_RS09945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACTEI_RS09965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACTEI_RS10000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACTEI_RS10010	COG2197	response regulator
ACTEI_RS10080	COG1674	ftsk spoiiie
ACTEI_RS10090	COG3940	Belongs to the glycosyl hydrolase 43 family
ACTEI_RS10110	COG0475	glutathione-regulated potassium exporter activity
ACTEI_RS10140	COG1376	ErfK ybiS ycfS ynhG family protein
ACTEI_RS10165	COG0589	response to stress
ACTEI_RS10180	COG0589	response to stress
ACTEI_RS10235	COG4221	oxidoreductase activity
ACTEI_RS10235	COG3321	synthase
ACTEI_RS10235	COG0604	alcohol dehydrogenase
ACTEI_RS10235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACTEI_RS10250	COG3507	Belongs to the glycosyl hydrolase 43 family
ACTEI_RS10275	COG3940	Belongs to the glycosyl hydrolase 43 family
ACTEI_RS10285	COG1175	transmembrane transport
ACTEI_RS10290	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS10295	COG3420	alginic acid biosynthetic process
ACTEI_RS10305	COG1473	amidohydrolase
ACTEI_RS10360	COG1846	Transcriptional regulator
ACTEI_RS10375	COG1131	(ABC) transporter
ACTEI_RS10380	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACTEI_RS10400	COG0640	Transcriptional regulator
ACTEI_RS10410	COG3321	synthase
ACTEI_RS10410	COG0604	alcohol dehydrogenase
ACTEI_RS10410	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS10445	COG0714	Associated with various cellular activities
ACTEI_RS10480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACTEI_RS10490	COG2814	Major facilitator Superfamily
ACTEI_RS10520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACTEI_RS10525	COG3537	Alpha-1,2-mannosidase
ACTEI_RS10615	COG1609	Transcriptional regulator
ACTEI_RS10635	COG0477	Major facilitator Superfamily
ACTEI_RS10660	COG0247	lactate metabolic process
ACTEI_RS10665	COG1139	Iron-sulfur cluster binding protein
ACTEI_RS10670	COG1556	Lactate utilization protein
ACTEI_RS10690	COG1136	(ABC) transporter
ACTEI_RS10695	COG0577	efflux transmembrane transporter activity
ACTEI_RS10695	COG1136	(ABC) transporter
ACTEI_RS10705	COG2409	Drug exporters of the RND superfamily
ACTEI_RS10715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACTEI_RS10730	COG4948	Mandelate Racemase Muconate Lactonizing
ACTEI_RS10745	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACTEI_RS10755	COG1918	ferrous iron import across plasma membrane
ACTEI_RS10755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACTEI_RS10800	COG0531	amino acid
ACTEI_RS10835	COG1116	anion transmembrane transporter activity
ACTEI_RS10840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACTEI_RS10855	COG1414	Transcriptional regulator
ACTEI_RS10880	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS10890	COG1414	Transcriptional regulator
ACTEI_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS10900	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ACTEI_RS10915	COG0546	phosphoglycolate phosphatase activity
ACTEI_RS10930	COG0363	glucosamine-6-phosphate deaminase activity
ACTEI_RS10935	COG1940	carbohydrate kinase activity
ACTEI_RS10940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACTEI_RS10945	COG1063	alcohol dehydrogenase
ACTEI_RS10965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACTEI_RS10970	COG4552	Acetyltransferase involved in intracellular survival and related
ACTEI_RS11000	COG0019	diaminopimelate decarboxylase activity
ACTEI_RS11015	COG0642	Histidine kinase
ACTEI_RS11040	COG2116	formate transmembrane transporter activity
ACTEI_RS11060	COG3591	Belongs to the peptidase S1B family
ACTEI_RS11060	COG1864	DNA RNA non-specific endonuclease
ACTEI_RS11105	COG1199	ATP-dependent helicase activity
ACTEI_RS11105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACTEI_RS11115	COG1472	Belongs to the glycosyl hydrolase 3 family
ACTEI_RS11120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACTEI_RS11130	COG1414	Transcriptional regulator
ACTEI_RS11135	COG3485	protocatechuate 3,4-dioxygenase
ACTEI_RS11140	COG3485	protocatechuate 3,4-dioxygenase
ACTEI_RS11150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACTEI_RS11195	COG3293	Transposase
ACTEI_RS11230	COG0039	L-malate dehydrogenase activity
ACTEI_RS11255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACTEI_RS11400	COG1396	sequence-specific DNA binding
ACTEI_RS11405	COG1316	TRANSCRIPTIONal
ACTEI_RS11430	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS11460	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS11470	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS11495	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACTEI_RS11500	COG1472	Belongs to the glycosyl hydrolase 3 family
ACTEI_RS11505	COG1609	Transcriptional regulator
ACTEI_RS11520	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS11525	COG1501	Belongs to the glycosyl hydrolase 31 family
ACTEI_RS11530	COG1595	DNA-templated transcription, initiation
ACTEI_RS11545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS11550	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACTEI_RS11560	COG1122	ATPase activity
ACTEI_RS11575	COG0310	cobalt ion transport
ACTEI_RS11595	COG5002	protein histidine kinase activity
ACTEI_RS11615	COG5002	protein histidine kinase activity
ACTEI_RS11645	COG3842	ATPase activity
ACTEI_RS11655	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACTEI_RS11660	COG1177	transmembrane transport
ACTEI_RS11665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACTEI_RS11670	COG1472	Belongs to the glycosyl hydrolase 3 family
ACTEI_RS11675	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS11690	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS11695	COG1472	Belongs to the glycosyl hydrolase 3 family
ACTEI_RS11705	COG1175	transmembrane transport
ACTEI_RS11715	COG1609	Transcriptional regulator
ACTEI_RS11720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS11745	COG3119	arylsulfatase activity
ACTEI_RS11750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACTEI_RS11760	COG3191	aminopeptidase activity
ACTEI_RS11775	COG0702	epimerase
ACTEI_RS11780	COG1733	regulation of RNA biosynthetic process
ACTEI_RS11795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACTEI_RS11805	COG0183	Belongs to the thiolase family
ACTEI_RS11845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACTEI_RS11850	COG4172	Belongs to the ABC transporter superfamily
ACTEI_RS11855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS11860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS11870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS11875	COG4941	Belongs to the sigma-70 factor family
ACTEI_RS11905	COG0456	acetyltransferase
ACTEI_RS11910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACTEI_RS11920	COG0765	amino acid transport
ACTEI_RS11925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACTEI_RS11930	COG4521	taurine ABC transporter
ACTEI_RS11945	COG5001	Diguanylate cyclase
ACTEI_RS11950	COG0366	Alpha amylase catalytic
ACTEI_RS11955	COG1609	Transcriptional regulator
ACTEI_RS11960	COG3237	CsbD-like
ACTEI_RS11965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS11970	COG2409	Drug exporters of the RND superfamily
ACTEI_RS11990	COG1132	(ABC) transporter
ACTEI_RS12000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACTEI_RS12010	COG0372	Belongs to the citrate synthase family
ACTEI_RS12025	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACTEI_RS12025	COG0596	Alpha beta hydrolase
ACTEI_RS12070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACTEI_RS12075	COG2146	nitrite reductase [NAD(P)H] activity
ACTEI_RS12080	COG2223	nitrite transmembrane transporter activity
ACTEI_RS12115	COG0577	efflux transmembrane transporter activity
ACTEI_RS12115	COG1136	(ABC) transporter
ACTEI_RS12120	COG1136	(ABC) transporter
ACTEI_RS12125	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS12130	COG1175	transmembrane transport
ACTEI_RS12135	COG1653	transport
ACTEI_RS12140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACTEI_RS12150	COG4733	cellulase activity
ACTEI_RS12150	COG5297	Belongs to the glycosyl hydrolase family 6
ACTEI_RS12165	COG3903	Transcriptional regulator
ACTEI_RS12165	COG3629	intracellular signal transduction
ACTEI_RS12170	COG0009	L-threonylcarbamoyladenylate synthase
ACTEI_RS12175	COG2084	Dehydrogenase
ACTEI_RS12180	COG0366	Alpha amylase catalytic
ACTEI_RS12200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS12205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACTEI_RS12225	COG0247	lactate metabolic process
ACTEI_RS12230	COG0277	FAD linked oxidase domain protein
ACTEI_RS12235	COG0277	FAD linked oxidase domain protein
ACTEI_RS12250	COG0574	Belongs to the PEP-utilizing enzyme family
ACTEI_RS12250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACTEI_RS12260	COG0514	ATP-dependent DNA helicase (RecQ)
ACTEI_RS12265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACTEI_RS12285	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS12295	COG1063	alcohol dehydrogenase
ACTEI_RS12305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACTEI_RS12315	COG0789	Transcriptional regulator
ACTEI_RS12350	COG0326	Molecular chaperone. Has ATPase activity
ACTEI_RS12360	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACTEI_RS12385	COG2197	response regulator
ACTEI_RS12390	COG0823	Involved in the tonB-independent uptake of proteins
ACTEI_RS12400	COG0464	growth
ACTEI_RS12505	COG1309	transcriptional regulator
ACTEI_RS12540	COG0477	Major facilitator Superfamily
ACTEI_RS12550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACTEI_RS12560	COG1132	(ABC) transporter
ACTEI_RS12560	COG2375	cellular response to nickel ion
ACTEI_RS12570	COG1294	oxidase, subunit
ACTEI_RS12575	COG1271	oxidase subunit
ACTEI_RS12585	COG0501	Belongs to the peptidase M48B family
ACTEI_RS12590	COG0791	NLP P60 protein
ACTEI_RS12590	COG3103	Sh3 type 3 domain protein
ACTEI_RS12590	COG1388	LysM domain
ACTEI_RS12595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACTEI_RS12635	COG0133	tryptophan synthase activity
ACTEI_RS12645	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS12665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACTEI_RS12685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACTEI_RS12715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACTEI_RS12720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACTEI_RS12740	COG0477	Major facilitator Superfamily
ACTEI_RS12750	COG3629	intracellular signal transduction
ACTEI_RS12755	COG1597	lipid kinase activity
ACTEI_RS12825	COG5002	protein histidine kinase activity
ACTEI_RS12830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACTEI_RS12835	COG4988	ABC transporter
ACTEI_RS12840	COG1294	oxidase, subunit
ACTEI_RS12845	COG1271	oxidase subunit
ACTEI_RS12855	COG2080	2 iron, 2 sulfur cluster binding
ACTEI_RS12855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACTEI_RS12945	COG0166	Belongs to the GPI family
ACTEI_RS12960	COG2226	methyltransferase
ACTEI_RS12990	COG1309	transcriptional regulator
ACTEI_RS13000	COG1045	serine acetyltransferase
ACTEI_RS13010	COG2076	Multidrug Resistance protein
ACTEI_RS13035	COG1140	nitrate reductase beta subunit
ACTEI_RS13045	COG2181	nitrate reductase activity
ACTEI_RS13070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACTEI_RS13090	COG0601	transmembrane transport
ACTEI_RS13105	COG4608	Belongs to the ABC transporter superfamily
ACTEI_RS13205	COG1940	carbohydrate kinase activity
ACTEI_RS13250	COG0406	alpha-ribazole phosphatase activity
ACTEI_RS13255	COG1609	Transcriptional regulator
ACTEI_RS13270	COG2197	response regulator
ACTEI_RS13290	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS13295	COG2205	protein histidine kinase activity
ACTEI_RS13300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACTEI_RS13305	COG0577	efflux transmembrane transporter activity
ACTEI_RS13305	COG1136	(ABC) transporter
ACTEI_RS13310	COG1136	(ABC) transporter
ACTEI_RS13310	COG0577	efflux transmembrane transporter activity
ACTEI_RS13335	COG3384	dioxygenase
ACTEI_RS13385	COG3396	Phenylacetate-CoA oxygenase
ACTEI_RS13390	COG3460	Phenylacetate-CoA oxygenase
ACTEI_RS13395	COG3396	Phenylacetate-CoA oxygenase
ACTEI_RS13400	COG2151	metal-sulfur cluster biosynthetic enzyme
ACTEI_RS13405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACTEI_RS13415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACTEI_RS13435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACTEI_RS13445	COG1408	metallophosphoesterase
ACTEI_RS13450	COG1072	(Pantothenic acid kinase))
ACTEI_RS13465	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACTEI_RS13465	COG4124	Belongs to the glycosyl hydrolase 26 family
ACTEI_RS13505	COG0515	serine threonine protein kinase
ACTEI_RS13515	COG0531	amino acid
ACTEI_RS13525	COG2124	cytochrome p450
ACTEI_RS13535	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACTEI_RS13555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACTEI_RS13595	COG0545	Peptidyl-prolyl cis-trans isomerase
ACTEI_RS13600	COG3022	response to hydroperoxide
ACTEI_RS13635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACTEI_RS13655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACTEI_RS13705	COG0789	Transcriptional regulator
ACTEI_RS13725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACTEI_RS13730	COG0778	Nitroreductase
ACTEI_RS13750	COG3540	Alkaline phosphatase
ACTEI_RS13785	COG0110	maltose O-acetyltransferase activity
ACTEI_RS13790	COG3226	Transcriptional regulator
ACTEI_RS13795	COG2223	nitrite transmembrane transporter activity
ACTEI_RS13800	COG3706	GGDEF domain
ACTEI_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS13845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACTEI_RS13855	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS13900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACTEI_RS13915	COG0640	Transcriptional regulator
ACTEI_RS13940	COG1509	lysine 2,3-aminomutase activity
ACTEI_RS13945	COG0604	alcohol dehydrogenase
ACTEI_RS13950	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ACTEI_RS13955	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACTEI_RS13960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACTEI_RS13965	COG1607	acyl-coa hydrolase
ACTEI_RS13980	COG0463	Glycosyl transferase, family 2
ACTEI_RS14000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACTEI_RS14020	COG3629	intracellular signal transduction
ACTEI_RS14020	COG3903	Transcriptional regulator
ACTEI_RS14035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS14050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACTEI_RS14055	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACTEI_RS14060	COG2080	2 iron, 2 sulfur cluster binding
ACTEI_RS14085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACTEI_RS14105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACTEI_RS14115	COG1733	regulation of RNA biosynthetic process
ACTEI_RS14120	COG1733	regulation of RNA biosynthetic process
ACTEI_RS14135	COG1982	Orn Lys Arg decarboxylase major
ACTEI_RS14140	COG2890	protein-(glutamine-N5) methyltransferase activity
ACTEI_RS14145	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACTEI_RS14170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS14230	COG0693	protein deglycase activity
ACTEI_RS14235	COG0840	transmembrane signaling receptor activity
ACTEI_RS14245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS14250	COG1309	transcriptional regulator
ACTEI_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS14275	COG0517	IMP dehydrogenase activity
ACTEI_RS14275	COG0516	GMP reductase activity
ACTEI_RS14285	COG1744	ABC transporter substrate-binding protein PnrA-like
ACTEI_RS14310	COG1316	TRANSCRIPTIONal
ACTEI_RS14345	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS14450	COG5001	Diguanylate cyclase
ACTEI_RS14450	COG3300	MHYT domain
ACTEI_RS14485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACTEI_RS14515	COG1064	alcohol dehydrogenase
ACTEI_RS14530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACTEI_RS14540	COG0673	inositol 2-dehydrogenase activity
ACTEI_RS14545	COG1260	myo-inositol-1-phosphate synthase
ACTEI_RS14555	COG0300	oxidoreductase activity
ACTEI_RS14570	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACTEI_RS14575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACTEI_RS14580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACTEI_RS14600	COG0561	phosphatase activity
ACTEI_RS14605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACTEI_RS14615	COG0546	phosphoglycolate phosphatase activity
ACTEI_RS14620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS14665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACTEI_RS14690	COG0488	(ABC) transporter
ACTEI_RS14720	COG0604	alcohol dehydrogenase
ACTEI_RS14725	COG0656	L-ascorbic acid biosynthetic process
ACTEI_RS14730	COG2814	Major facilitator Superfamily
ACTEI_RS14745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACTEI_RS14755	COG5002	protein histidine kinase activity
ACTEI_RS14760	COG5002	protein histidine kinase activity
ACTEI_RS14780	COG0300	oxidoreductase activity
ACTEI_RS14795	COG2211	Major facilitator Superfamily
ACTEI_RS14825	COG3629	intracellular signal transduction
ACTEI_RS14830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACTEI_RS14835	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS14850	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS14880	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS14905	COG1533	DNA photolyase activity
ACTEI_RS14910	COG1506	peptidase
ACTEI_RS14910	COG0823	Involved in the tonB-independent uptake of proteins
ACTEI_RS14925	COG1609	Transcriptional regulator
ACTEI_RS14935	COG3876	Protein conserved in bacteria
ACTEI_RS14975	COG2197	response regulator
ACTEI_RS14980	COG1914	H( )-stimulated, divalent metal cation uptake system
ACTEI_RS14985	COG3546	catalase activity
ACTEI_RS14995	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ACTEI_RS15010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACTEI_RS15035	COG3866	Pectate lyase
ACTEI_RS15045	COG3866	Pectate lyase
ACTEI_RS15075	COG3409	Peptidoglycan-binding domain 1 protein
ACTEI_RS15105	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS15115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACTEI_RS15125	COG0367	asparagine synthase
ACTEI_RS15135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACTEI_RS15155	COG3285	dna ligase
ACTEI_RS15155	COG1793	dna ligase
ACTEI_RS15170	COG1846	Transcriptional regulator
ACTEI_RS15185	COG1794	racemase activity, acting on amino acids and derivatives
ACTEI_RS15245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACTEI_RS15280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACTEI_RS15300	COG1595	DNA-templated transcription, initiation
ACTEI_RS15310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACTEI_RS15320	COG0604	alcohol dehydrogenase
ACTEI_RS15330	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS15340	COG3396	Phenylacetate-CoA oxygenase
ACTEI_RS15350	COG3396	Phenylacetate-CoA oxygenase
ACTEI_RS15355	COG2151	metal-sulfur cluster biosynthetic enzyme
ACTEI_RS15360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACTEI_RS15365	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS15370	COG3483	tryptophan 2,3-dioxygenase activity
ACTEI_RS15390	COG2205	protein histidine kinase activity
ACTEI_RS15395	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS15425	COG0277	FAD linked oxidase domain protein
ACTEI_RS15430	COG2205	protein histidine kinase activity
ACTEI_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS15515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACTEI_RS15525	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACTEI_RS15530	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ACTEI_RS15545	COG2205	protein histidine kinase activity
ACTEI_RS15550	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS15600	COG1132	(ABC) transporter
ACTEI_RS15610	COG2124	cytochrome p450
ACTEI_RS15615	COG2124	cytochrome p450
ACTEI_RS15620	COG2124	cytochrome p450
ACTEI_RS15630	COG2124	cytochrome p450
ACTEI_RS15645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACTEI_RS15650	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS15655	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACTEI_RS15665	COG2197	response regulator
ACTEI_RS15675	COG1024	Enoyl-CoA hydratase
ACTEI_RS15680	COG1024	Enoyl-CoA hydratase
ACTEI_RS15685	COG1024	Enoyl-CoA hydratase
ACTEI_RS15695	COG0302	gtp cyclohydrolase
ACTEI_RS15710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACTEI_RS15740	COG3903	Transcriptional regulator
ACTEI_RS15740	COG3629	intracellular signal transduction
ACTEI_RS15750	COG3293	Transposase
ACTEI_RS15765	COG0789	Transcriptional regulator
ACTEI_RS15770	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACTEI_RS15775	COG1121	(ABC) transporter
ACTEI_RS15780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACTEI_RS15810	COG1309	transcriptional regulator
ACTEI_RS15830	COG2755	lipolytic protein G-D-S-L family
ACTEI_RS15840	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACTEI_RS15855	COG2203	Gaf domain
ACTEI_RS15855	COG2199	diguanylate cyclase activity
ACTEI_RS15865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACTEI_RS15865	COG2205	protein histidine kinase activity
ACTEI_RS15945	COG1175	transmembrane transport
ACTEI_RS15965	COG3046	protein related to deoxyribodipyrimidine photolyase
ACTEI_RS15985	COG2197	response regulator
ACTEI_RS15995	COG2311	Membrane
ACTEI_RS16000	COG2267	carboxylic ester hydrolase activity
ACTEI_RS16015	COG2936	dipeptidyl-peptidase activity
ACTEI_RS16030	COG1064	alcohol dehydrogenase
ACTEI_RS16045	COG5001	Diguanylate cyclase
ACTEI_RS16045	COG3300	MHYT domain
ACTEI_RS16055	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS16060	COG1175	transmembrane transport
ACTEI_RS16075	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACTEI_RS16095	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS16105	COG5002	protein histidine kinase activity
ACTEI_RS16115	COG1295	ribonuclease BN
ACTEI_RS16125	COG1454	alcohol dehydrogenase
ACTEI_RS16125	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS16145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACTEI_RS16160	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACTEI_RS16230	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS16235	COG5002	protein histidine kinase activity
ACTEI_RS16240	COG2357	RelA SpoT domain protein
ACTEI_RS16260	COG2072	flavoprotein involved in K transport
ACTEI_RS16320	COG1309	transcriptional regulator
ACTEI_RS16330	COG5002	protein histidine kinase activity
ACTEI_RS16355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACTEI_RS16370	COG3509	depolymerase
ACTEI_RS16395	COG0640	Transcriptional regulator
ACTEI_RS16475	COG0596	Alpha beta hydrolase
ACTEI_RS16480	COG3629	intracellular signal transduction
ACTEI_RS16480	COG3903	Transcriptional regulator
ACTEI_RS16515	COG0701	Predicted permease
ACTEI_RS16540	COG0653	protein targeting
ACTEI_RS16545	COG3293	Transposase
ACTEI_RS16555	COG0559	Belongs to the binding-protein-dependent transport system permease family
ACTEI_RS16575	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS16605	COG5297	Belongs to the glycosyl hydrolase family 6
ACTEI_RS16635	COG1690	Belongs to the RtcB family
ACTEI_RS16640	COG2124	cytochrome p450
ACTEI_RS16665	COG2239	Acts as a magnesium transporter
ACTEI_RS16675	COG0574	Belongs to the PEP-utilizing enzyme family
ACTEI_RS16675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACTEI_RS16690	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ACTEI_RS16740	COG1295	ribonuclease BN
ACTEI_RS16760	COG0784	Response regulator, receiver
ACTEI_RS16775	COG2200	EAL domain
ACTEI_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS16800	COG0583	DNA-binding transcription factor activity
ACTEI_RS16825	COG0577	efflux transmembrane transporter activity
ACTEI_RS16830	COG0577	efflux transmembrane transporter activity
ACTEI_RS16830	COG1136	(ABC) transporter
ACTEI_RS16835	COG4585	Histidine kinase
ACTEI_RS16840	COG2197	response regulator
ACTEI_RS16915	COG0583	DNA-binding transcription factor activity
ACTEI_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS16960	COG3629	intracellular signal transduction
ACTEI_RS16970	COG0583	DNA-binding transcription factor activity
ACTEI_RS16990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACTEI_RS17015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACTEI_RS17105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACTEI_RS17125	COG0242	peptide deformylase activity
ACTEI_RS17135	COG2318	DinB family
ACTEI_RS17145	COG0494	nUDIX hydrolase
ACTEI_RS17155	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS17195	COG3300	MHYT domain
ACTEI_RS17195	COG5001	Diguanylate cyclase
ACTEI_RS17245	COG0024	Methionine aminopeptidase
ACTEI_RS17255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS17365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACTEI_RS17370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACTEI_RS17390	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACTEI_RS17415	COG0640	Transcriptional regulator
ACTEI_RS17450	COG1309	transcriptional regulator
ACTEI_RS17465	COG4941	Belongs to the sigma-70 factor family
ACTEI_RS17470	COG5002	protein histidine kinase activity
ACTEI_RS17495	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACTEI_RS17515	COG2197	response regulator
ACTEI_RS17530	COG1404	Belongs to the peptidase S8 family
ACTEI_RS17535	COG0531	amino acid
ACTEI_RS17545	COG0789	Transcriptional regulator
ACTEI_RS17555	COG1073	alpha beta
ACTEI_RS17555	COG2226	methyltransferase
ACTEI_RS17565	COG2259	Doxx family
ACTEI_RS17605	COG4677	pectinesterase activity
ACTEI_RS17610	COG1063	alcohol dehydrogenase
ACTEI_RS17680	COG1191	sigma factor activity
ACTEI_RS17685	COG4974	Belongs to the 'phage' integrase family
ACTEI_RS17690	COG1968	undecaprenyl-diphosphatase activity
ACTEI_RS17740	COG3173	Aminoglycoside phosphotransferase
ACTEI_RS17760	COG0583	DNA-binding transcription factor activity
ACTEI_RS17765	COG5006	permease, DMT superfamily
ACTEI_RS17825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACTEI_RS17845	COG2197	response regulator
ACTEI_RS17865	COG2270	Major facilitator Superfamily
ACTEI_RS17895	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ACTEI_RS17900	COG0667	Aldo Keto reductase
ACTEI_RS17955	COG1764	response to oxidative stress
ACTEI_RS17960	COG1846	Transcriptional regulator
ACTEI_RS17975	COG1959	2 iron, 2 sulfur cluster binding
ACTEI_RS17995	COG4702	Belongs to the UPF0303 family
ACTEI_RS18020	COG0019	diaminopimelate decarboxylase activity
ACTEI_RS18035	COG2197	response regulator
ACTEI_RS18060	COG0583	DNA-binding transcription factor activity
ACTEI_RS18065	COG0183	Belongs to the thiolase family
ACTEI_RS18075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACTEI_RS18100	COG3300	MHYT domain
ACTEI_RS18100	COG5001	Diguanylate cyclase
ACTEI_RS18135	COG3537	Alpha-1,2-mannosidase
ACTEI_RS18145	COG0714	Associated with various cellular activities
ACTEI_RS18170	COG3693	PFAM glycoside hydrolase, family 10
ACTEI_RS18180	COG3507	Belongs to the glycosyl hydrolase 43 family
ACTEI_RS18185	COG3345	alpha-galactosidase
ACTEI_RS18225	COG2356	endonuclease I
ACTEI_RS18230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACTEI_RS18235	COG0242	peptide deformylase activity
ACTEI_RS18245	COG1595	DNA-templated transcription, initiation
ACTEI_RS18250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACTEI_RS18260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACTEI_RS18260	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACTEI_RS18265	COG0667	Aldo Keto reductase
ACTEI_RS18310	COG1289	transmembrane transporter activity
ACTEI_RS18325	COG0672	)-iron permease
ACTEI_RS18335	COG2837	iron assimilation
ACTEI_RS18375	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS18380	COG1132	(ABC) transporter
ACTEI_RS18385	COG4251	negative regulation of phosphorylation
ACTEI_RS18390	COG0569	domain protein
ACTEI_RS18395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACTEI_RS18400	COG0025	NhaP-type Na H and K H
ACTEI_RS18420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACTEI_RS18495	COG4249	Peptidase C14 caspase catalytic subunit p20
ACTEI_RS18495	COG2319	Wd-40 repeat
ACTEI_RS18505	COG3293	Transposase
ACTEI_RS18520	COG2197	response regulator
ACTEI_RS18560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS18575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACTEI_RS18585	COG3973	AAA domain
ACTEI_RS18600	COG1136	(ABC) transporter
ACTEI_RS18600	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACTEI_RS18605	COG1136	(ABC) transporter
ACTEI_RS18605	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACTEI_RS18630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACTEI_RS18690	COG3629	intracellular signal transduction
ACTEI_RS18690	COG3903	Transcriptional regulator
ACTEI_RS18695	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACTEI_RS18840	COG1733	regulation of RNA biosynthetic process
ACTEI_RS18845	COG0309	Hydrogenase expression formation protein (HypE)
ACTEI_RS18855	COG0298	carbon dioxide binding
ACTEI_RS18860	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ACTEI_RS18885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACTEI_RS18890	COG0589	response to stress
ACTEI_RS18975	COG1090	epimerase
ACTEI_RS18980	COG0667	Aldo Keto reductase
ACTEI_RS19080	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS19085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACTEI_RS19105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACTEI_RS19140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACTEI_RS19145	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACTEI_RS19185	COG0247	lactate metabolic process
ACTEI_RS19185	COG0277	FAD linked oxidase domain protein
ACTEI_RS19200	COG1606	tRNA processing
ACTEI_RS19210	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ACTEI_RS19235	COG0583	DNA-binding transcription factor activity
ACTEI_RS19260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS19300	COG4251	negative regulation of phosphorylation
ACTEI_RS19325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACTEI_RS19325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACTEI_RS19330	COG0494	nUDIX hydrolase
ACTEI_RS19355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACTEI_RS19420	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS19425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACTEI_RS19425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACTEI_RS19435	COG0297	glycogen (starch) synthase activity
ACTEI_RS19445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACTEI_RS19455	COG2192	nodulation
ACTEI_RS19470	COG4221	oxidoreductase activity
ACTEI_RS19520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS19525	COG1022	Amp-dependent synthetase and ligase
ACTEI_RS19540	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS19545	COG2080	2 iron, 2 sulfur cluster binding
ACTEI_RS19550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACTEI_RS19555	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACTEI_RS19555	COG3608	succinylglutamate desuccinylase aspartoacylase
ACTEI_RS19570	COG2072	flavoprotein involved in K transport
ACTEI_RS19580	COG2080	2 iron, 2 sulfur cluster binding
ACTEI_RS19585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACTEI_RS19590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACTEI_RS19645	COG4221	oxidoreductase activity
ACTEI_RS19655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACTEI_RS19680	COG0673	inositol 2-dehydrogenase activity
ACTEI_RS19685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACTEI_RS19715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACTEI_RS19720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACTEI_RS19725	COG0022	dehydrogenase e1 component
ACTEI_RS19730	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACTEI_RS19730	COG0022	dehydrogenase e1 component
ACTEI_RS19810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACTEI_RS19850	COG4122	O-methyltransferase activity
ACTEI_RS19855	COG1442	glycosyl transferase family 8
ACTEI_RS19855	COG1216	Glycosyl transferase, family 2
ACTEI_RS19860	COG1595	DNA-templated transcription, initiation
ACTEI_RS19905	COG0596	Alpha beta hydrolase
ACTEI_RS19980	COG1959	2 iron, 2 sulfur cluster binding
ACTEI_RS19985	COG1024	Enoyl-CoA hydratase
ACTEI_RS20010	COG0667	Aldo Keto reductase
ACTEI_RS20035	COG0010	Belongs to the arginase family
ACTEI_RS20045	COG0667	Aldo Keto reductase
ACTEI_RS20075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACTEI_RS20080	COG5001	Diguanylate cyclase
ACTEI_RS20110	COG1760	l-serine dehydratase
ACTEI_RS20115	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACTEI_RS20120	COG1846	Transcriptional regulator
ACTEI_RS20125	COG2814	Major facilitator Superfamily
ACTEI_RS20140	COG2197	response regulator
ACTEI_RS20150	COG1266	CAAX protease self-immunity
ACTEI_RS20190	COG3706	GGDEF domain
ACTEI_RS20195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACTEI_RS20205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACTEI_RS20210	COG1652	LysM domain
ACTEI_RS20215	COG0300	oxidoreductase activity
ACTEI_RS20220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACTEI_RS20220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACTEI_RS20230	COG0515	serine threonine protein kinase
ACTEI_RS20230	COG2815	serine threonine protein kinase
ACTEI_RS20240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACTEI_RS20245	COG1215	transferase activity, transferring glycosyl groups
ACTEI_RS20260	COG1011	Hydrolase
ACTEI_RS20265	COG3467	pyridoxamine 5'-phosphate
ACTEI_RS20305	COG0784	Response regulator, receiver
ACTEI_RS20325	COG0321	lipoyl(octanoyl) transferase activity
ACTEI_RS20350	COG2124	cytochrome p450
ACTEI_RS20360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACTEI_RS20385	COG3961	Belongs to the TPP enzyme family
ACTEI_RS20395	COG5001	Diguanylate cyclase
ACTEI_RS20425	COG1063	alcohol dehydrogenase
ACTEI_RS20430	COG3973	AAA domain
ACTEI_RS20520	COG0730	response to heat
ACTEI_RS20560	COG1902	pentaerythritol trinitrate reductase activity
ACTEI_RS20595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACTEI_RS20600	COG1063	alcohol dehydrogenase
ACTEI_RS20610	COG0483	inositol monophosphate 1-phosphatase activity
ACTEI_RS20620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS20635	COG3119	arylsulfatase activity
ACTEI_RS20650	COG1131	(ABC) transporter
ACTEI_RS20690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACTEI_RS20695	COG0697	spore germination
ACTEI_RS20740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACTEI_RS20750	COG0596	Alpha beta hydrolase
ACTEI_RS20760	COG0714	Associated with various cellular activities
ACTEI_RS20765	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ACTEI_RS20795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACTEI_RS20830	COG1716	ATPase activity
ACTEI_RS20835	COG0509	glycine decarboxylation via glycine cleavage system
ACTEI_RS20865	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ACTEI_RS20870	COG0384	phenazine biosynthesis protein PhzF
ACTEI_RS20875	COG0477	Major facilitator Superfamily
ACTEI_RS20880	COG3447	MASE1 domain protein
ACTEI_RS20880	COG5001	Diguanylate cyclase
ACTEI_RS20880	COG5002	protein histidine kinase activity
ACTEI_RS20885	COG0488	(ABC) transporter
ACTEI_RS20890	COG1649	PFAM Uncharacterised BCR, COG1649
ACTEI_RS20895	COG0297	glycogen (starch) synthase activity
ACTEI_RS20900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACTEI_RS20950	COG2501	S4 domain
ACTEI_RS20965	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACTEI_RS20970	COG1366	Belongs to the anti-sigma-factor antagonist family
ACTEI_RS20975	COG1940	carbohydrate kinase activity
ACTEI_RS20990	COG4214	carbohydrate transport
ACTEI_RS20995	COG1129	ABC transporter
ACTEI_RS21000	COG4213	ABC transporter substrate-binding protein
ACTEI_RS21005	COG2160	L-arabinose isomerase activity
ACTEI_RS21010	COG1609	Transcriptional regulator
ACTEI_RS21045	COG5006	permease, DMT superfamily
ACTEI_RS21090	COG0840	transmembrane signaling receptor activity
ACTEI_RS21095	COG0643	Histidine kinase
ACTEI_RS21095	COG2198	Histidine kinase
ACTEI_RS21100	COG2201	protein-glutamate methylesterase activity
ACTEI_RS21110	COG0577	efflux transmembrane transporter activity
ACTEI_RS21110	COG1136	(ABC) transporter
ACTEI_RS21115	COG1136	(ABC) transporter
ACTEI_RS21115	COG0577	efflux transmembrane transporter activity
ACTEI_RS21125	COG2197	response regulator
ACTEI_RS21155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACTEI_RS21160	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACTEI_RS21165	COG0251	oxidation-reduction process
ACTEI_RS21180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACTEI_RS21190	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS21200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACTEI_RS21245	COG3551	Protein conserved in bacteria
ACTEI_RS21260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACTEI_RS21265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACTEI_RS21270	COG1120	ATPase activity
ACTEI_RS21280	COG0579	oxidoreductase
ACTEI_RS21285	COG1742	UPF0060 membrane protein
ACTEI_RS21295	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS21325	COG2814	Major facilitator Superfamily
ACTEI_RS21380	COG4585	Histidine kinase
ACTEI_RS21385	COG0577	efflux transmembrane transporter activity
ACTEI_RS21385	COG1136	(ABC) transporter
ACTEI_RS21400	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS21445	COG3903	Transcriptional regulator
ACTEI_RS21445	COG3629	intracellular signal transduction
ACTEI_RS21525	COG0546	phosphoglycolate phosphatase activity
ACTEI_RS21540	COG0805	protein transport
ACTEI_RS21545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACTEI_RS21555	COG2378	regulation of single-species biofilm formation
ACTEI_RS21585	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACTEI_RS21590	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACTEI_RS21595	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACTEI_RS21605	COG4122	O-methyltransferase activity
ACTEI_RS21620	COG1222	aaa ATPase
ACTEI_RS21640	COG1994	Peptidase M50
ACTEI_RS21640	COG0517	IMP dehydrogenase activity
ACTEI_RS21675	COG1136	(ABC) transporter
ACTEI_RS21675	COG0577	efflux transmembrane transporter activity
ACTEI_RS21680	COG0577	efflux transmembrane transporter activity
ACTEI_RS21680	COG1136	(ABC) transporter
ACTEI_RS21715	COG0215	cysteine-tRNA ligase activity
ACTEI_RS21735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS21740	COG0667	Aldo Keto reductase
ACTEI_RS21755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACTEI_RS21770	COG0542	response to heat
ACTEI_RS21795	COG1674	ftsk spoiiie
ACTEI_RS21810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACTEI_RS21810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACTEI_RS21840	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS21850	COG0653	protein targeting
ACTEI_RS21880	COG1797	cobyrinic acid a,c-diamide synthase activity
ACTEI_RS21925	COG5012	cobalamin binding
ACTEI_RS21945	COG1643	Atp-dependent helicase
ACTEI_RS21950	COG0784	Response regulator, receiver
ACTEI_RS21955	COG4251	negative regulation of phosphorylation
ACTEI_RS21975	COG1191	sigma factor activity
ACTEI_RS22015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACTEI_RS22020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACTEI_RS22030	COG2183	response to ionizing radiation
ACTEI_RS22070	COG5297	Belongs to the glycosyl hydrolase family 6
ACTEI_RS22075	COG5001	Diguanylate cyclase
ACTEI_RS22085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACTEI_RS22095	COG0584	glycerophosphoryl diester phosphodiesterase
ACTEI_RS22125	COG5001	Diguanylate cyclase
ACTEI_RS22125	COG5002	protein histidine kinase activity
ACTEI_RS22160	COG0515	serine threonine protein kinase
ACTEI_RS22220	COG3866	Pectate lyase
ACTEI_RS22235	COG0246	Mannitol dehydrogenase
ACTEI_RS22240	COG1904	glucuronate isomerase
ACTEI_RS22245	COG0673	inositol 2-dehydrogenase activity
ACTEI_RS22260	COG1175	transmembrane transport
ACTEI_RS22265	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS22300	COG2011	ABC-type metal ion transport system permease component
ACTEI_RS22315	COG2197	response regulator
ACTEI_RS22320	COG4585	Histidine kinase
ACTEI_RS22350	COG1486	melibiose metabolic process
ACTEI_RS22365	COG1175	transmembrane transport
ACTEI_RS22400	COG0840	transmembrane signaling receptor activity
ACTEI_RS22405	COG0477	Major facilitator Superfamily
ACTEI_RS22420	COG1017	nitric oxide dioxygenase activity
ACTEI_RS22420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACTEI_RS22425	COG0515	serine threonine protein kinase
ACTEI_RS22435	COG1132	(ABC) transporter
ACTEI_RS22440	COG1132	(ABC) transporter
ACTEI_RS22445	COG2197	response regulator
ACTEI_RS22465	COG1653	transport
ACTEI_RS22470	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS22475	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS22500	COG2409	Drug exporters of the RND superfamily
ACTEI_RS22530	COG2160	L-arabinose isomerase activity
ACTEI_RS22535	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACTEI_RS22540	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACTEI_RS22550	COG1879	ABC-type sugar transport system periplasmic component
ACTEI_RS22555	COG1609	Transcriptional regulator
ACTEI_RS22605	COG2130	NADP-dependent
ACTEI_RS22615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACTEI_RS22625	COG2205	protein histidine kinase activity
ACTEI_RS22635	COG0840	transmembrane signaling receptor activity
ACTEI_RS22650	COG1131	(ABC) transporter
ACTEI_RS22700	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS22715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACTEI_RS22720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACTEI_RS22735	COG0656	L-ascorbic acid biosynthetic process
ACTEI_RS22760	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ACTEI_RS22765	COG3458	cephalosporin-C deacetylase activity
ACTEI_RS22770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACTEI_RS22795	COG1461	Dihydroxyacetone kinase
ACTEI_RS22800	COG2376	Dihydroxyacetone kinase
ACTEI_RS22820	COG0183	Belongs to the thiolase family
ACTEI_RS22825	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS22840	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS22845	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS22855	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS22865	COG0492	ferredoxin-NADP+ reductase activity
ACTEI_RS22870	COG1476	TRANSCRIPTIONal
ACTEI_RS22875	COG1024	Enoyl-CoA hydratase
ACTEI_RS22910	COG2199	diguanylate cyclase activity
ACTEI_RS22910	COG2200	EAL domain
ACTEI_RS22910	COG2202	Pas domain
ACTEI_RS22925	COG2910	NAD(P)H-binding
ACTEI_RS22980	COG0667	Aldo Keto reductase
ACTEI_RS22985	COG0477	Major facilitator Superfamily
ACTEI_RS22990	COG1309	transcriptional regulator
ACTEI_RS23005	COG0489	protein tyrosine kinase activity
ACTEI_RS23005	COG3206	protein involved in exopolysaccharide biosynthesis
ACTEI_RS23030	COG0297	glycogen (starch) synthase activity
ACTEI_RS23040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACTEI_RS23045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACTEI_RS23050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACTEI_RS23095	COG1435	thymidine kinase activity
ACTEI_RS23110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACTEI_RS23115	COG1116	anion transmembrane transporter activity
ACTEI_RS23125	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACTEI_RS23165	COG5001	Diguanylate cyclase
ACTEI_RS23210	COG3507	Belongs to the glycosyl hydrolase 43 family
ACTEI_RS23220	COG4172	Belongs to the ABC transporter superfamily
ACTEI_RS23225	COG0601	transmembrane transport
ACTEI_RS23230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACTEI_RS23235	COG0747	negative chemotaxis
ACTEI_RS23300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACTEI_RS23305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACTEI_RS23315	COG1414	Transcriptional regulator
ACTEI_RS23320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACTEI_RS23345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACTEI_RS23410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACTEI_RS23420	COG1086	Polysaccharide biosynthesis protein
ACTEI_RS23430	COG2197	response regulator
ACTEI_RS23435	COG0477	Major facilitator Superfamily
ACTEI_RS23450	COG3300	MHYT domain
ACTEI_RS23450	COG5001	Diguanylate cyclase
ACTEI_RS23460	COG4565	transcriptional regulatory protein
ACTEI_RS23465	COG3290	protein histidine kinase activity
ACTEI_RS23470	COG1301	dicarboxylic acid transport
ACTEI_RS23855	COG3617	BRO family, N-terminal domain
ACTEI_RS23885	COG2409	Drug exporters of the RND superfamily
ACTEI_RS23890	COG4585	Histidine kinase
ACTEI_RS23895	COG2197	response regulator
ACTEI_RS23905	COG3511	phospholipase C
ACTEI_RS23915	COG1132	(ABC) transporter
ACTEI_RS23940	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ACTEI_RS23945	COG1132	(ABC) transporter
ACTEI_RS23955	COG0515	serine threonine protein kinase
ACTEI_RS23960	COG5001	Diguanylate cyclase
ACTEI_RS23960	COG3447	MASE1 domain protein
ACTEI_RS23960	COG5002	protein histidine kinase activity
ACTEI_RS23985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACTEI_RS23990	COG0019	diaminopimelate decarboxylase activity
ACTEI_RS24000	COG4677	pectinesterase activity
ACTEI_RS24065	COG3537	Alpha-1,2-mannosidase
ACTEI_RS24105	COG1278	Cold shock
ACTEI_RS24120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACTEI_RS24130	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS24175	COG1921	L-seryl-tRNASec selenium transferase activity
ACTEI_RS24185	COG0709	Synthesizes selenophosphate from selenide and ATP
ACTEI_RS24200	COG0437	4 iron, 4 sulfur cluster binding
ACTEI_RS24205	COG3383	formate dehydrogenase (NAD+) activity
ACTEI_RS24205	COG0243	molybdopterin cofactor binding
ACTEI_RS24210	COG3383	formate dehydrogenase (NAD+) activity
ACTEI_RS24210	COG0243	molybdopterin cofactor binding
ACTEI_RS24305	COG3104	oligopeptide transport
ACTEI_RS24345	COG4585	Histidine kinase
ACTEI_RS24350	COG2197	response regulator
ACTEI_RS24390	COG2814	Major facilitator Superfamily
ACTEI_RS24395	COG0723	plastoquinol--plastocyanin reductase activity
ACTEI_RS24395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACTEI_RS24425	COG1404	Belongs to the peptidase S8 family
ACTEI_RS24445	COG4842	Belongs to the WXG100 family
ACTEI_RS24455	COG1674	ftsk spoiiie
ACTEI_RS24500	COG4214	carbohydrate transport
ACTEI_RS24505	COG4213	ABC transporter substrate-binding protein
ACTEI_RS24550	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS24565	COG2755	lipolytic protein G-D-S-L family
ACTEI_RS24565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACTEI_RS24590	COG0483	inositol monophosphate 1-phosphatase activity
ACTEI_RS24595	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS24620	COG0246	Mannitol dehydrogenase
ACTEI_RS24640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACTEI_RS24660	COG2201	protein-glutamate methylesterase activity
ACTEI_RS24675	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS24685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACTEI_RS24755	COG0515	serine threonine protein kinase
ACTEI_RS24760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACTEI_RS24775	COG0778	Nitroreductase
ACTEI_RS24780	COG2890	protein-(glutamine-N5) methyltransferase activity
ACTEI_RS24800	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACTEI_RS24815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACTEI_RS24820	COG0604	alcohol dehydrogenase
ACTEI_RS24830	COG0604	alcohol dehydrogenase
ACTEI_RS24830	COG3321	synthase
ACTEI_RS24845	COG0604	alcohol dehydrogenase
ACTEI_RS24845	COG3321	synthase
ACTEI_RS24850	COG0604	alcohol dehydrogenase
ACTEI_RS24850	COG0604	alcohol dehydrogenase
ACTEI_RS24850	COG3321	synthase
ACTEI_RS24850	COG3321	synthase
ACTEI_RS24855	COG3321	synthase
ACTEI_RS24855	COG0604	alcohol dehydrogenase
ACTEI_RS24865	COG0546	phosphoglycolate phosphatase activity
ACTEI_RS24880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACTEI_RS24885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS24905	COG4251	negative regulation of phosphorylation
ACTEI_RS24965	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACTEI_RS24975	COG1121	(ABC) transporter
ACTEI_RS24980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACTEI_RS24990	COG3693	PFAM glycoside hydrolase, family 10
ACTEI_RS25030	COG0569	domain protein
ACTEI_RS25030	COG2985	domain, Protein
ACTEI_RS25050	COG0596	Alpha beta hydrolase
ACTEI_RS25085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACTEI_RS25100	COG0477	Major facilitator Superfamily
ACTEI_RS25105	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACTEI_RS25165	COG0300	oxidoreductase activity
ACTEI_RS25170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACTEI_RS25175	COG0475	glutathione-regulated potassium exporter activity
ACTEI_RS25210	COG1129	ABC transporter
ACTEI_RS25225	COG3509	depolymerase
ACTEI_RS25235	COG3693	PFAM glycoside hydrolase, family 10
ACTEI_RS25265	COG4977	sequence-specific DNA binding
ACTEI_RS25270	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS25305	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS25310	COG1309	transcriptional regulator
ACTEI_RS25340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS25350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACTEI_RS25355	COG0367	asparagine synthase
ACTEI_RS25360	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACTEI_RS25370	COG2124	cytochrome p450
ACTEI_RS25395	COG1819	glycosyl
ACTEI_RS25400	COG1819	glycosyl
ACTEI_RS25405	COG3708	Transcriptional regulator
ACTEI_RS25405	COG2207	Transcriptional regulator
ACTEI_RS25415	COG2124	cytochrome p450
ACTEI_RS25430	COG0604	alcohol dehydrogenase
ACTEI_RS25430	COG3321	synthase
ACTEI_RS25465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS25475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACTEI_RS25480	COG0596	Alpha beta hydrolase
ACTEI_RS25580	COG0667	Aldo Keto reductase
ACTEI_RS25660	COG4974	Belongs to the 'phage' integrase family
ACTEI_RS25680	COG2205	protein histidine kinase activity
ACTEI_RS25685	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS25745	COG3629	intracellular signal transduction
ACTEI_RS25745	COG3903	Transcriptional regulator
ACTEI_RS25770	COG3293	Transposase
ACTEI_RS25810	COG3293	Transposase
ACTEI_RS25895	COG1160	GTP binding
ACTEI_RS25920	COG2197	response regulator
ACTEI_RS25955	COG2814	Major facilitator Superfamily
ACTEI_RS25960	COG0583	DNA-binding transcription factor activity
ACTEI_RS25970	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS25980	COG0596	Alpha beta hydrolase
ACTEI_RS25985	COG1187	pseudouridine synthase activity
ACTEI_RS25990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACTEI_RS26060	COG1733	regulation of RNA biosynthetic process
ACTEI_RS26085	COG0494	nUDIX hydrolase
ACTEI_RS26090	COG0504	CTP synthase activity
ACTEI_RS26130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACTEI_RS26165	COG0647	UMP catabolic process
ACTEI_RS26205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACTEI_RS26210	COG2326	polyphosphate kinase activity
ACTEI_RS26225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACTEI_RS26230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACTEI_RS26235	COG1063	alcohol dehydrogenase
ACTEI_RS26240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACTEI_RS26240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACTEI_RS26290	COG2094	Belongs to the DNA glycosylase MPG family
ACTEI_RS26300	COG3973	AAA domain
ACTEI_RS26305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACTEI_RS26330	COG0730	response to heat
ACTEI_RS26345	COG3833	ABC-type maltose transport systems, permease component
ACTEI_RS26350	COG1175	transmembrane transport
ACTEI_RS26365	COG0165	Argininosuccinate lyase
ACTEI_RS26370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACTEI_RS26375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACTEI_RS26385	COG0137	argininosuccinate synthase activity
ACTEI_RS26400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACTEI_RS26405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACTEI_RS26410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACTEI_RS26415	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACTEI_RS26420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACTEI_RS26425	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACTEI_RS26435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACTEI_RS26445	COG1472	Belongs to the glycosyl hydrolase 3 family
ACTEI_RS26475	COG0072	phenylalanine-tRNA ligase activity
ACTEI_RS26475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACTEI_RS26480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACTEI_RS26485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACTEI_RS26490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACTEI_RS26495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACTEI_RS26500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACTEI_RS26510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACTEI_RS26515	COG0140	phosphoribosyl-ATP diphosphatase activity
ACTEI_RS26525	COG0765	amino acid transport
ACTEI_RS26535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACTEI_RS26540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACTEI_RS26540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACTEI_RS26565	COG0204	Acyl-transferase
ACTEI_RS26570	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS26590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACTEI_RS26595	COG0242	peptide deformylase activity
ACTEI_RS26605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACTEI_RS26615	COG1758	RNA polymerase activity
ACTEI_RS26620	COG0194	GDP metabolic process
ACTEI_RS26630	COG0284	orotidine-5'-phosphate decarboxylase activity
ACTEI_RS26635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACTEI_RS26640	COG0167	dihydroorotate dehydrogenase activity
ACTEI_RS26650	COG0505	Belongs to the CarA family
ACTEI_RS26655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACTEI_RS26660	COG0540	Belongs to the ATCase OTCase family
ACTEI_RS26665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACTEI_RS26675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACTEI_RS26680	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACTEI_RS26685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACTEI_RS26690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACTEI_RS26695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACTEI_RS26700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACTEI_RS26705	COG2814	Major facilitator Superfamily
ACTEI_RS26715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACTEI_RS26720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACTEI_RS26725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACTEI_RS26730	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACTEI_RS26735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACTEI_RS26805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACTEI_RS26820	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
ACTEI_RS26835	COG3964	amidohydrolase
ACTEI_RS26845	COG0515	serine threonine protein kinase
ACTEI_RS26850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACTEI_RS26850	COG2755	lipolytic protein G-D-S-L family
ACTEI_RS26855	COG0831	urea catabolic process
ACTEI_RS26860	COG0832	Belongs to the urease beta subunit family
ACTEI_RS26875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACTEI_RS26880	COG0829	nickel cation binding
ACTEI_RS26900	COG0189	ligase activity
ACTEI_RS26900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACTEI_RS26905	COG4242	Belongs to the peptidase S51 family
ACTEI_RS26925	COG0124	histidyl-tRNA synthetase
ACTEI_RS26945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACTEI_RS26950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACTEI_RS26965	COG1862	Preprotein translocase
ACTEI_RS26970	COG2255	four-way junction helicase activity
ACTEI_RS26975	COG0632	four-way junction helicase activity
ACTEI_RS26980	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACTEI_RS26990	COG0217	transcriptional regulatory protein
ACTEI_RS26995	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ACTEI_RS27005	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACTEI_RS27015	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS27020	COG1560	Kdo2-lipid A biosynthetic process
ACTEI_RS27060	COG2205	protein histidine kinase activity
ACTEI_RS27070	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACTEI_RS27080	COG0667	Aldo Keto reductase
ACTEI_RS27090	COG1278	Cold shock
ACTEI_RS27130	COG1472	Belongs to the glycosyl hydrolase 3 family
ACTEI_RS27135	COG0514	ATP-dependent DNA helicase (RecQ)
ACTEI_RS27150	COG2197	response regulator
ACTEI_RS27155	COG4585	Histidine kinase
ACTEI_RS27165	COG1131	(ABC) transporter
ACTEI_RS27170	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS27225	COG0668	transmembrane transport
ACTEI_RS27265	COG0542	response to heat
ACTEI_RS27290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACTEI_RS27300	COG4266	Belongs to the allantoicase family
ACTEI_RS27305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACTEI_RS27320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACTEI_RS27335	COG2351	hydroxyisourate hydrolase activity
ACTEI_RS27345	COG1643	Atp-dependent helicase
ACTEI_RS27370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACTEI_RS27475	COG2205	protein histidine kinase activity
ACTEI_RS27475	COG2202	Pas domain
ACTEI_RS27480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACTEI_RS27490	COG0405	Gamma-glutamyltransferase
ACTEI_RS27500	COG2133	pyrroloquinoline quinone binding
ACTEI_RS27515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACTEI_RS27520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACTEI_RS27530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACTEI_RS27555	COG1309	transcriptional regulator
ACTEI_RS27560	COG4221	oxidoreductase activity
ACTEI_RS27585	COG1686	Belongs to the peptidase S11 family
ACTEI_RS27595	COG1191	sigma factor activity
ACTEI_RS27605	COG3973	AAA domain
ACTEI_RS27615	COG1191	sigma factor activity
ACTEI_RS27620	COG0513	Belongs to the DEAD box helicase family
ACTEI_RS27645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACTEI_RS27650	COG1609	Transcriptional regulator
ACTEI_RS27665	COG0601	transmembrane transport
ACTEI_RS27670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACTEI_RS27675	COG0444	Belongs to the ABC transporter superfamily
ACTEI_RS27685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACTEI_RS27690	COG3903	Transcriptional regulator
ACTEI_RS27690	COG3629	intracellular signal transduction
ACTEI_RS27730	COG0656	L-ascorbic acid biosynthetic process
ACTEI_RS27750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACTEI_RS27755	COG0187	DNA topoisomerase II activity
ACTEI_RS27765	COG2197	response regulator
ACTEI_RS27785	COG0435	Glutathione S-transferase
ACTEI_RS27790	COG1846	Transcriptional regulator
ACTEI_RS27825	COG1846	Transcriptional regulator
ACTEI_RS27830	COG0697	spore germination
ACTEI_RS27845	COG0714	Associated with various cellular activities
ACTEI_RS27865	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ACTEI_RS27870	COG2895	sulfate adenylyltransferase (ATP) activity
ACTEI_RS27870	COG0529	Catalyzes the synthesis of activated sulfate
ACTEI_RS27920	COG0494	nUDIX hydrolase
ACTEI_RS27935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACTEI_RS27975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACTEI_RS27980	COG1017	nitric oxide dioxygenase activity
ACTEI_RS27980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACTEI_RS27995	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS28020	COG2755	lipolytic protein G-D-S-L family
ACTEI_RS28035	COG0515	serine threonine protein kinase
ACTEI_RS28045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACTEI_RS28050	COG0598	Magnesium transport protein CorA
ACTEI_RS28055	COG3201	nicotinamide mononucleotide transporter
ACTEI_RS28060	COG3135	benzoate transporter
ACTEI_RS28075	COG0436	Aminotransferase
ACTEI_RS28100	COG2205	protein histidine kinase activity
ACTEI_RS28105	COG2205	protein histidine kinase activity
ACTEI_RS28150	COG1476	TRANSCRIPTIONal
ACTEI_RS28155	COG0604	alcohol dehydrogenase
ACTEI_RS28175	COG0512	Glutamine amidotransferase of anthranilate synthase
ACTEI_RS28200	COG2197	response regulator
ACTEI_RS28205	COG4585	Histidine kinase
ACTEI_RS28225	COG0702	epimerase
ACTEI_RS28230	COG0702	epimerase
ACTEI_RS28235	COG1396	sequence-specific DNA binding
ACTEI_RS28240	COG0740	serine-type endopeptidase activity
ACTEI_RS28245	COG0740	serine-type endopeptidase activity
ACTEI_RS28285	COG1733	regulation of RNA biosynthetic process
ACTEI_RS28300	COG1518	maintenance of DNA repeat elements
ACTEI_RS28470	COG3293	Transposase
ACTEI_RS28480	COG0443	Heat shock 70 kDa protein
ACTEI_RS28565	COG0741	lytic transglycosylase activity
ACTEI_RS28565	COG0739	heme binding
ACTEI_RS28565	COG1196	nuclear chromosome segregation
ACTEI_RS28615	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ACTEI_RS28675	COG2318	DinB family
ACTEI_RS28690	COG0671	phosphoesterase, PA-phosphatase related
ACTEI_RS28700	COG1803	Methylglyoxal synthase
ACTEI_RS28700	COG1597	lipid kinase activity
ACTEI_RS28735	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS28765	COG2197	response regulator
ACTEI_RS28805	COG1335	isochorismatase
ACTEI_RS28830	COG0800	Aldolase
ACTEI_RS28850	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ACTEI_RS28855	COG0366	Alpha amylase catalytic
ACTEI_RS28860	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS28865	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS28880	COG2226	methyltransferase
ACTEI_RS28890	COG0673	inositol 2-dehydrogenase activity
ACTEI_RS28905	COG3483	tryptophan 2,3-dioxygenase activity
ACTEI_RS28910	COG3012	SEC-C Motif Domain Protein
ACTEI_RS28920	COG1609	Transcriptional regulator
ACTEI_RS28930	COG1175	transmembrane transport
ACTEI_RS28940	COG0366	Alpha amylase catalytic
ACTEI_RS28955	COG0659	secondary active sulfate transmembrane transporter activity
ACTEI_RS28965	COG2308	Evidence 4 Homologs of previously reported genes of
ACTEI_RS28965	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACTEI_RS28970	COG0367	asparagine synthase
ACTEI_RS28975	COG1506	peptidase
ACTEI_RS28980	COG0542	response to heat
ACTEI_RS29020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACTEI_RS29025	COG0561	phosphatase activity
ACTEI_RS29070	COG2197	response regulator
ACTEI_RS29075	COG4585	Histidine kinase
ACTEI_RS29095	COG1131	(ABC) transporter
ACTEI_RS29100	COG0328	RNA-DNA hybrid ribonuclease activity
ACTEI_RS29115	COG5001	Diguanylate cyclase
ACTEI_RS29125	COG1793	dna ligase
ACTEI_RS29125	COG3285	dna ligase
ACTEI_RS29185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACTEI_RS29210	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS29260	COG2807	transmembrane transport
ACTEI_RS29270	COG0058	SHG alpha-glucan phosphorylase activity
ACTEI_RS29280	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ACTEI_RS29305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACTEI_RS29320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACTEI_RS29340	COG1131	(ABC) transporter
ACTEI_RS29350	COG0142	geranyltranstransferase activity
ACTEI_RS29365	COG0367	asparagine synthase
ACTEI_RS29375	COG2192	nodulation
ACTEI_RS29390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACTEI_RS29415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACTEI_RS29425	COG1132	(ABC) transporter
ACTEI_RS29430	COG0726	polysaccharide deacetylase
ACTEI_RS29450	COG1136	(ABC) transporter
ACTEI_RS29470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACTEI_RS29490	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS29505	COG0657	acetylesterase activity
ACTEI_RS29515	COG0840	transmembrane signaling receptor activity
ACTEI_RS29545	COG3903	Transcriptional regulator
ACTEI_RS29545	COG3629	intracellular signal transduction
ACTEI_RS29555	COG2197	response regulator
ACTEI_RS29560	COG4585	Histidine kinase
ACTEI_RS29575	COG0840	transmembrane signaling receptor activity
ACTEI_RS29585	COG1937	Protein conserved in bacteria
ACTEI_RS29605	COG1937	Protein conserved in bacteria
ACTEI_RS29645	COG1733	regulation of RNA biosynthetic process
ACTEI_RS29650	COG0702	epimerase
ACTEI_RS29690	COG2304	oxidoreductase activity
ACTEI_RS29705	COG0714	Associated with various cellular activities
ACTEI_RS29710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACTEI_RS29735	COG5002	protein histidine kinase activity
ACTEI_RS29740	COG5297	Belongs to the glycosyl hydrolase family 6
ACTEI_RS29740	COG3250	beta-galactosidase activity
ACTEI_RS29815	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACTEI_RS29820	COG1129	ABC transporter
ACTEI_RS29855	COG1477	protein flavinylation
ACTEI_RS29865	COG0543	2 iron, 2 sulfur cluster binding
ACTEI_RS29865	COG0633	Ferredoxin
ACTEI_RS29895	COG4977	sequence-specific DNA binding
ACTEI_RS29930	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ACTEI_RS29950	COG0395	ABC-type sugar transport system, permease component
ACTEI_RS29955	COG1175	transmembrane transport
ACTEI_RS29965	COG1609	Transcriptional regulator
ACTEI_RS29975	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS29980	COG5001	Diguanylate cyclase
ACTEI_RS30000	COG2197	response regulator
ACTEI_RS30025	COG2409	Drug exporters of the RND superfamily
ACTEI_RS30035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACTEI_RS30055	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS30075	COG2264	protein methyltransferase activity
ACTEI_RS30085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACTEI_RS30090	COG0156	8-amino-7-oxononanoate synthase activity
ACTEI_RS30095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACTEI_RS30120	COG0420	3'-5' exonuclease activity
ACTEI_RS30125	COG0419	ATPase involved in DNA repair
ACTEI_RS30190	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACTEI_RS30235	COG1793	dna ligase
ACTEI_RS30245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACTEI_RS30270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACTEI_RS30280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACTEI_RS30285	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACTEI_RS30300	COG3253	May function as heme-dependent peroxidase
ACTEI_RS30305	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ACTEI_RS30310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACTEI_RS30320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACTEI_RS30325	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACTEI_RS30330	COG0183	Belongs to the thiolase family
ACTEI_RS30335	COG1024	Enoyl-CoA hydratase
ACTEI_RS30335	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACTEI_RS30340	COG2205	protein histidine kinase activity
ACTEI_RS30345	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS30360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACTEI_RS30365	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACTEI_RS30380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACTEI_RS30385	COG0531	amino acid
ACTEI_RS30390	COG0569	domain protein
ACTEI_RS30415	COG0756	dUTP diphosphatase activity
ACTEI_RS30455	COG3706	GGDEF domain
ACTEI_RS30465	COG2860	membrane
ACTEI_RS30475	COG2313	pseudouridylate synthase activity
ACTEI_RS30505	COG0840	transmembrane signaling receptor activity
ACTEI_RS30510	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS30520	COG0643	Histidine kinase
ACTEI_RS30520	COG0784	Response regulator, receiver
ACTEI_RS30520	COG2198	Histidine kinase
ACTEI_RS30520	COG2198	Histidine kinase
ACTEI_RS30520	COG0784	Response regulator, receiver
ACTEI_RS30520	COG0643	Histidine kinase
ACTEI_RS30530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACTEI_RS30540	COG2201	protein-glutamate methylesterase activity
ACTEI_RS30550	COG0840	transmembrane signaling receptor activity
ACTEI_RS30560	COG1490	D-aminoacyl-tRNA deacylase activity
ACTEI_RS30580	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACTEI_RS30605	COG0738	Major facilitator superfamily
ACTEI_RS30620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACTEI_RS30625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACTEI_RS30630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACTEI_RS30640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACTEI_RS30655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACTEI_RS30660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACTEI_RS30665	COG1196	nuclear chromosome segregation
ACTEI_RS30680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACTEI_RS30690	COG1126	abc transporter atp-binding protein
ACTEI_RS30695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACTEI_RS30700	COG0765	amino acid transport
ACTEI_RS30705	COG0765	amino acid transport
ACTEI_RS30710	COG1418	mRNA catabolic process
ACTEI_RS30715	COG2137	regulation of response to DNA damage stimulus
ACTEI_RS30720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACTEI_RS30730	COG1573	uracil-dna glycosylase
ACTEI_RS30750	COG1201	RNA secondary structure unwinding
ACTEI_RS30770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACTEI_RS30780	COG1842	Phage shock protein A
ACTEI_RS30785	COG1396	sequence-specific DNA binding
ACTEI_RS30790	COG1546	Belongs to the CinA family
ACTEI_RS30790	COG1058	Belongs to the CinA family
ACTEI_RS30800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACTEI_RS30820	COG1674	ftsk spoiiie
ACTEI_RS30835	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACTEI_RS30840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACTEI_RS30850	COG3214	Protein conserved in bacteria
ACTEI_RS30860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACTEI_RS30865	COG0612	Peptidase, M16
ACTEI_RS30870	COG1185	polyribonucleotide nucleotidyltransferase activity
ACTEI_RS30875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACTEI_RS30885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACTEI_RS30885	COG2205	protein histidine kinase activity
ACTEI_RS30890	COG0784	Response regulator, receiver
ACTEI_RS30890	COG2198	Histidine kinase
ACTEI_RS30890	COG5002	protein histidine kinase activity
ACTEI_RS30895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACTEI_RS30905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACTEI_RS30910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACTEI_RS30925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACTEI_RS30940	COG0779	Required for maturation of 30S ribosomal subunits
ACTEI_RS30980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACTEI_RS30985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACTEI_RS30995	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS31010	COG1668	transmembrane transport
ACTEI_RS31015	COG4152	abc transporter atp-binding protein
ACTEI_RS31020	COG2197	response regulator
ACTEI_RS31025	COG4585	Histidine kinase
ACTEI_RS31030	COG1309	transcriptional regulator
ACTEI_RS31035	COG1511	domain protein
ACTEI_RS31050	COG0640	Transcriptional regulator
ACTEI_RS31065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACTEI_RS31070	COG0750	zinc metalloprotease
ACTEI_RS31090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACTEI_RS31090	COG2146	nitrite reductase [NAD(P)H] activity
ACTEI_RS31105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACTEI_RS31115	COG0233	cytoplasmic translational termination
ACTEI_RS31120	COG0528	UMP kinase activity
ACTEI_RS31125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACTEI_RS31130	COG0052	Belongs to the universal ribosomal protein uS2 family
ACTEI_RS31140	COG0792	nuclease activity
ACTEI_RS31165	COG2186	Transcriptional regulator
ACTEI_RS31180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACTEI_RS31195	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACTEI_RS31200	COG0494	nUDIX hydrolase
ACTEI_RS31205	COG0681	Belongs to the peptidase S26 family
ACTEI_RS31210	COG0681	Belongs to the peptidase S26 family
ACTEI_RS31215	COG0335	large ribosomal subunit rRNA binding
ACTEI_RS31220	COG0336	Belongs to the RNA methyltransferase TrmD family
ACTEI_RS31225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACTEI_RS31230	COG1837	Belongs to the UPF0109 family
ACTEI_RS31235	COG0228	four-way junction DNA binding
ACTEI_RS31245	COG0442	prolyl-tRNA aminoacylation
ACTEI_RS31270	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS31285	COG0463	Glycosyl transferase, family 2
ACTEI_RS31295	COG2755	lipolytic protein G-D-S-L family
ACTEI_RS31295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACTEI_RS31310	COG1216	Glycosyl transferase, family 2
ACTEI_RS31325	COG1215	transferase activity, transferring glycosyl groups
ACTEI_RS31330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACTEI_RS31385	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS31400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACTEI_RS31410	COG0571	ribonuclease III activity
ACTEI_RS31415	COG0416	fatty acid biosynthetic process
ACTEI_RS31420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACTEI_RS31435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACTEI_RS31440	COG0742	ribosomal rna small subunit methyltransferase
ACTEI_RS31465	COG1461	Dihydroxyacetone kinase
ACTEI_RS31470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACTEI_RS31495	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACTEI_RS31510	COG0626	cystathionine gamma-synthase activity
ACTEI_RS31515	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACTEI_RS31525	COG1920	GTP binding
ACTEI_RS31535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACTEI_RS31550	COG0776	regulation of translation
ACTEI_RS31555	COG0066	3-isopropylmalate dehydratase activity
ACTEI_RS31595	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACTEI_RS31620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACTEI_RS31645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACTEI_RS31650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACTEI_RS31665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACTEI_RS31670	COG0473	3-isopropylmalate dehydrogenase activity
ACTEI_RS31685	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACTEI_RS31690	COG0440	acetolactate synthase activity
ACTEI_RS31700	COG5001	Diguanylate cyclase
ACTEI_RS31700	COG3300	MHYT domain
ACTEI_RS31705	COG0129	dihydroxy-acid dehydratase activity
ACTEI_RS31710	COG1609	Transcriptional regulator
ACTEI_RS31715	COG5001	Diguanylate cyclase
ACTEI_RS31715	COG4251	negative regulation of phosphorylation
ACTEI_RS31715	COG2203	Gaf domain
ACTEI_RS31715	COG3706	GGDEF domain
ACTEI_RS31725	COG2133	pyrroloquinoline quinone binding
ACTEI_RS31760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACTEI_RS31765	COG0154	amidase activity
ACTEI_RS31770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACTEI_RS31780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACTEI_RS31790	COG0482	sulfurtransferase activity
ACTEI_RS31800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACTEI_RS31810	COG2149	membrane
ACTEI_RS31830	COG1024	Enoyl-CoA hydratase
ACTEI_RS31845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACTEI_RS31850	COG1119	ATPase activity
ACTEI_RS31860	COG1472	Belongs to the glycosyl hydrolase 3 family
ACTEI_RS31870	COG2902	Dehydrogenase
ACTEI_RS31885	COG0010	Belongs to the arginase family
ACTEI_RS31905	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACTEI_RS31905	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACTEI_RS31910	COG1703	isobutyryl-CoA mutase activity
ACTEI_RS31915	COG0183	Belongs to the thiolase family
ACTEI_RS31965	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ACTEI_RS31980	COG1674	ftsk spoiiie
ACTEI_RS31990	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACTEI_RS32020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACTEI_RS32030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACTEI_RS32035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACTEI_RS32040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACTEI_RS32045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACTEI_RS32050	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACTEI_RS32055	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACTEI_RS32060	COG0356	it plays a direct role in the translocation of protons across the membrane
ACTEI_RS32075	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACTEI_RS32080	COG0702	epimerase
ACTEI_RS32085	COG0009	L-threonylcarbamoyladenylate synthase
ACTEI_RS32090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACTEI_RS32100	COG2890	protein-(glutamine-N5) methyltransferase activity
ACTEI_RS32115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACTEI_RS32120	COG0254	rRNA binding
ACTEI_RS32140	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ACTEI_RS32150	COG0083	homoserine kinase activity
ACTEI_RS32160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACTEI_RS32170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACTEI_RS32180	COG0460	homoserine dehydrogenase
ACTEI_RS32185	COG0019	diaminopimelate decarboxylase activity
ACTEI_RS32190	COG0018	arginyl-trna synthetase
ACTEI_RS32210	COG0681	Belongs to the peptidase S26 family
ACTEI_RS32215	COG0525	valine-tRNA ligase activity
ACTEI_RS32270	COG0673	inositol 2-dehydrogenase activity
ACTEI_RS32285	COG0754	glutathionylspermidine amidase activity
ACTEI_RS32305	COG0366	Alpha amylase catalytic
ACTEI_RS32310	COG0586	Pfam SNARE associated Golgi protein
ACTEI_RS32315	COG3469	chitinase activity
ACTEI_RS32330	COG0706	membrane insertase activity
ACTEI_RS32340	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACTEI_RS32360	COG0740	serine-type endopeptidase activity
ACTEI_RS32375	COG1834	amidinotransferase
ACTEI_RS32380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACTEI_RS32405	COG0789	Transcriptional regulator
ACTEI_RS32420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACTEI_RS32425	COG2205	protein histidine kinase activity
ACTEI_RS32430	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS32445	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACTEI_RS32445	COG0567	Dehydrogenase, E1 component
ACTEI_RS32450	COG0280	phosphate acetyltransferase
ACTEI_RS32450	COG0857	belongs to the CobB CobQ family
ACTEI_RS32455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACTEI_RS32480	COG2172	sigma factor antagonist activity
ACTEI_RS32485	COG2188	Transcriptional regulator
ACTEI_RS32495	COG1597	lipid kinase activity
ACTEI_RS32510	COG0175	sulfate reduction
ACTEI_RS32530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACTEI_RS32540	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ACTEI_RS32550	COG1595	DNA-templated transcription, initiation
ACTEI_RS32565	COG2135	peptidase activity
ACTEI_RS32570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACTEI_RS32575	COG1162	GTPase activity
ACTEI_RS32580	COG0483	inositol monophosphate 1-phosphatase activity
ACTEI_RS32645	COG1357	PFAM Pentapeptide repeats (8 copies)
ACTEI_RS32660	COG0463	Glycosyl transferase, family 2
ACTEI_RS32680	COG1396	sequence-specific DNA binding
ACTEI_RS32695	COG1615	UPF0182 protein
ACTEI_RS32700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACTEI_RS32725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACTEI_RS32765	COG2816	NAD+ diphosphatase activity
ACTEI_RS32780	COG1959	2 iron, 2 sulfur cluster binding
ACTEI_RS32790	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACTEI_RS32810	COG1278	Cold shock
ACTEI_RS32825	COG1074	ATP-dependent DNA helicase activity
ACTEI_RS32830	COG1611	Belongs to the LOG family
ACTEI_RS32835	COG1611	Belongs to the LOG family
ACTEI_RS32845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACTEI_RS32850	COG2171	N-acyltransferase activity
ACTEI_RS32870	COG2226	methyltransferase
ACTEI_RS32890	COG4221	oxidoreductase activity
ACTEI_RS32910	COG0456	acetyltransferase
ACTEI_RS32925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACTEI_RS32930	COG0823	Involved in the tonB-independent uptake of proteins
ACTEI_RS32930	COG1506	peptidase
ACTEI_RS32950	COG1053	succinate dehydrogenase
ACTEI_RS32970	COG1396	sequence-specific DNA binding
ACTEI_RS33015	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS33020	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS33030	COG1960	acyl-CoA dehydrogenase activity
ACTEI_RS33040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACTEI_RS33055	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS33130	COG0012	GTP binding
ACTEI_RS33140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACTEI_RS33140	COG2169	Transcriptional regulator
ACTEI_RS33160	COG1322	Protein conserved in bacteria
ACTEI_RS33165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACTEI_RS33180	COG1570	exodeoxyribonuclease VII activity
ACTEI_RS33185	COG1722	exodeoxyribonuclease VII activity
ACTEI_RS33200	COG0705	Rhomboid family
ACTEI_RS33215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACTEI_RS33225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACTEI_RS33230	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ACTEI_RS33235	COG1595	DNA-templated transcription, initiation
ACTEI_RS33265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACTEI_RS33295	COG1404	Belongs to the peptidase S8 family
ACTEI_RS33300	COG0424	maF-like protein
ACTEI_RS33305	COG0640	Transcriptional regulator
ACTEI_RS33310	COG4770	biotin carboxylase activity
ACTEI_RS33370	COG1473	amidohydrolase
ACTEI_RS33370	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACTEI_RS33375	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACTEI_RS33375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACTEI_RS33380	COG2815	serine threonine protein kinase
ACTEI_RS33380	COG0515	serine threonine protein kinase
ACTEI_RS33385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACTEI_RS33395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ACTEI_RS33400	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACTEI_RS33405	COG1216	Glycosyl transferase, family 2
ACTEI_RS33410	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS33420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACTEI_RS33430	COG1012	belongs to the aldehyde dehydrogenase family
ACTEI_RS33460	COG2018	Roadblock/LC7 domain
ACTEI_RS33470	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACTEI_RS33495	COG1079	Belongs to the binding-protein-dependent transport system permease family
ACTEI_RS33500	COG4603	Belongs to the binding-protein-dependent transport system permease family
ACTEI_RS33505	COG3845	ABC transporter
ACTEI_RS33510	COG1744	ABC transporter substrate-binding protein PnrA-like
ACTEI_RS33530	COG3409	Peptidoglycan-binding domain 1 protein
ACTEI_RS33550	COG0180	Tryptophanyl-tRNA synthetase
ACTEI_RS33555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACTEI_RS33560	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACTEI_RS33570	COG2205	protein histidine kinase activity
ACTEI_RS33585	COG1218	3'(2'),5'-bisphosphate nucleotidase
ACTEI_RS33595	COG0193	aminoacyl-tRNA hydrolase activity
ACTEI_RS33610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACTEI_RS33635	COG0488	(ABC) transporter
ACTEI_RS33640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACTEI_RS33645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACTEI_RS33650	COG0084	hydrolase, TatD family'
ACTEI_RS33665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACTEI_RS33720	COG0303	'Molybdopterin
ACTEI_RS33725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACTEI_RS33740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACTEI_RS33785	COG2095	MarC family integral membrane protein
ACTEI_RS33790	COG0613	PHP domain protein
ACTEI_RS33825	COG1028	Short-chain dehydrogenase reductase Sdr
ACTEI_RS33840	COG1011	Hydrolase
ACTEI_RS33850	COG0384	phenazine biosynthesis protein PhzF
ACTEI_RS33855	COG2239	Acts as a magnesium transporter
ACTEI_RS33870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACTEI_RS33875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACTEI_RS33885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACTEI_RS33900	COG1024	Enoyl-CoA hydratase
ACTEI_RS33910	COG0519	Catalyzes the synthesis of GMP from XMP
ACTEI_RS33925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACTEI_RS33930	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACTEI_RS33930	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACTEI_RS33935	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACTEI_RS33940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACTEI_RS33965	COG0113	porphobilinogen synthase activity
ACTEI_RS33970	COG1648	precorrin-2 dehydrogenase activity
ACTEI_RS33970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACTEI_RS33975	COG0181	hydroxymethylbilane synthase activity
ACTEI_RS33980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACTEI_RS33985	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ACTEI_RS34000	COG0318	PFAM AMP-dependent synthetase and ligase
ACTEI_RS34005	COG1595	DNA-templated transcription, initiation
ACTEI_RS34035	COG0506	proline dehydrogenase activity
ACTEI_RS34045	COG1082	Xylose isomerase domain protein TIM barrel
ACTEI_RS34070	COG0588	phosphoglycerate mutase activity
ACTEI_RS34090	COG0438	transferase activity, transferring glycosyl groups
ACTEI_RS34105	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS34120	COG5002	protein histidine kinase activity
ACTEI_RS34135	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACTEI_RS34140	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ACTEI_RS34150	COG4786	Flagellar basal body rod
ACTEI_RS34150	COG1256	bacterial-type flagellum assembly
ACTEI_RS34160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACTEI_RS34170	COG1516	flagellar protein fliS
ACTEI_RS34180	COG1815	bacterial-type flagellum-dependent cell motility
ACTEI_RS34190	COG1677	Flagellar hook-basal body complex protein FliE
ACTEI_RS34195	COG1766	The M ring may be actively involved in energy transduction
ACTEI_RS34200	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACTEI_RS34210	COG1157	protein secretion by the type III secretion system
ACTEI_RS34220	COG0741	lytic transglycosylase activity
ACTEI_RS34240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACTEI_RS34245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACTEI_RS34255	COG1338	Plays a role in the flagellum-specific transport system
ACTEI_RS34265	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACTEI_RS34265	COG1776	CheC inhibitor of MCP methylation
ACTEI_RS34270	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACTEI_RS34280	COG1360	Flagellar Motor Protein
ACTEI_RS34285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACTEI_RS34300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACTEI_RS34310	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS34320	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS34330	COG2201	protein-glutamate methylesterase activity
ACTEI_RS34345	COG0643	Histidine kinase
ACTEI_RS34345	COG2198	Histidine kinase
ACTEI_RS34345	COG0784	Response regulator, receiver
ACTEI_RS34350	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS34360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACTEI_RS34390	COG1191	sigma factor activity
ACTEI_RS34430	COG3246	L-lysine catabolic process to acetate
ACTEI_RS34440	COG0735	belongs to the Fur family
ACTEI_RS34450	COG4044	May play a role in the intracellular transport of hydrophobic ligands
ACTEI_RS34480	COG1595	DNA-templated transcription, initiation
ACTEI_RS34495	COG0306	phosphate transporter
ACTEI_RS34510	COG3459	Glycosyltransferase 36 associated
ACTEI_RS34515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACTEI_RS34535	COG0456	acetyltransferase
ACTEI_RS34540	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS34575	COG2339	peptidase activity
ACTEI_RS34605	COG0459	protein refolding
ACTEI_RS34620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACTEI_RS34630	COG1131	(ABC) transporter
ACTEI_RS34635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACTEI_RS34650	COG1131	(ABC) transporter
ACTEI_RS34655	COG1349	DNA-binding transcription factor activity
ACTEI_RS34725	COG3842	ATPase activity
ACTEI_RS34735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACTEI_RS34740	COG0215	cysteine-tRNA ligase activity
ACTEI_RS34750	COG0114	fumarate hydratase activity
ACTEI_RS34765	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACTEI_RS34765	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACTEI_RS34785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACTEI_RS34815	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACTEI_RS34820	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACTEI_RS34845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACTEI_RS34860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACTEI_RS34865	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ACTEI_RS34880	COG0242	peptide deformylase activity
ACTEI_RS34885	COG3830	Belongs to the UPF0237 family
ACTEI_RS34890	COG1194	a g-specific adenine glycosylase
ACTEI_RS34910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACTEI_RS34915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACTEI_RS34925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACTEI_RS34935	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACTEI_RS34940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACTEI_RS34955	COG0649	NAD binding
ACTEI_RS34970	COG1174	glycine betaine transport
ACTEI_RS34975	COG1174	glycine betaine transport
ACTEI_RS35010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACTEI_RS35045	COG0739	heme binding
ACTEI_RS35060	COG1674	ftsk spoiiie
ACTEI_RS35075	COG0302	gtp cyclohydrolase
ACTEI_RS35080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACTEI_RS35090	COG0037	tRNA processing
ACTEI_RS35100	COG2027	D-alanyl-D-alanine carboxypeptidase
ACTEI_RS35105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACTEI_RS35115	COG1674	ftsk spoiiie
ACTEI_RS35140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACTEI_RS35145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACTEI_RS35150	COG2843	Capsule synthesis protein
ACTEI_RS35165	COG4770	biotin carboxylase activity
ACTEI_RS35180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACTEI_RS35205	COG0003	Pfam Anion-transporting ATPase
ACTEI_RS35220	COG1610	YqeY-like protein
ACTEI_RS35225	COG1408	metallophosphoesterase
ACTEI_RS35250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACTEI_RS35275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACTEI_RS35305	COG4608	Belongs to the ABC transporter superfamily
ACTEI_RS35320	COG0747	negative chemotaxis
ACTEI_RS35325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACTEI_RS35330	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACTEI_RS35375	COG0813	purine-nucleoside phosphorylase activity
ACTEI_RS35400	COG0287	Prephenate dehydrogenase
ACTEI_RS35405	COG2318	DinB family
ACTEI_RS35410	COG0235	Class ii aldolase
ACTEI_RS35410	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACTEI_RS35415	COG0501	Belongs to the peptidase M48B family
ACTEI_RS35420	COG1796	DNA polymerase
ACTEI_RS35420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACTEI_RS35435	COG0642	Histidine kinase
ACTEI_RS35440	COG2018	Roadblock/LC7 domain
ACTEI_RS35550	COG0778	Nitroreductase
ACTEI_RS35560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACTEI_RS35585	COG2205	protein histidine kinase activity
ACTEI_RS35590	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS35625	COG1268	BioY protein
ACTEI_RS35635	COG0667	Aldo Keto reductase
ACTEI_RS35650	COG1131	(ABC) transporter
ACTEI_RS35660	COG1595	DNA-templated transcription, initiation
ACTEI_RS35675	COG0673	inositol 2-dehydrogenase activity
ACTEI_RS35680	COG0243	molybdopterin cofactor binding
ACTEI_RS35700	COG1435	thymidine kinase activity
ACTEI_RS35710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACTEI_RS35760	COG4638	Rieske (2fe-2S)
ACTEI_RS35765	COG3629	intracellular signal transduction
ACTEI_RS35765	COG3903	Transcriptional regulator
ACTEI_RS35770	COG0475	glutathione-regulated potassium exporter activity
ACTEI_RS35785	COG0151	Belongs to the GarS family
ACTEI_RS35795	COG4865	methylaspartate mutase activity
ACTEI_RS35800	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACTEI_RS35805	COG0302	gtp cyclohydrolase
ACTEI_RS35815	COG0720	synthase
ACTEI_RS35820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACTEI_RS35825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACTEI_RS35830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACTEI_RS35835	COG3629	intracellular signal transduction
ACTEI_RS35835	COG3903	Transcriptional regulator
ACTEI_RS35850	COG0456	acetyltransferase
ACTEI_RS35875	COG0596	Alpha beta hydrolase
ACTEI_RS35895	COG2197	response regulator
ACTEI_RS35910	COG1131	(ABC) transporter
ACTEI_RS35920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACTEI_RS35950	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACTEI_RS36000	COG2226	methyltransferase
ACTEI_RS36005	COG1881	PFAM PEBP family protein
ACTEI_RS36040	COG0789	Transcriptional regulator
ACTEI_RS36045	COG3959	Transketolase, thiamine diphosphate binding domain
ACTEI_RS36050	COG3958	Transketolase
ACTEI_RS36070	COG0705	Rhomboid family
ACTEI_RS36090	COG0598	Magnesium transport protein CorA
ACTEI_RS36095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACTEI_RS36105	COG0371	Dehydrogenase
ACTEI_RS36120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACTEI_RS36125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACTEI_RS36130	COG3275	phosphorelay sensor kinase activity
ACTEI_RS36135	COG3279	Response regulator of the LytR AlgR family
ACTEI_RS36140	COG0745	RESPONSE REGULATOR receiver
ACTEI_RS36145	COG2205	protein histidine kinase activity
ACTEI_RS36160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACTEI_RS36185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACTEI_RS36190	COG1316	TRANSCRIPTIONal
ACTEI_RS36195	COG1316	TRANSCRIPTIONal
ACTEI_RS36220	COG2235	arginine
ACTEI_RS36255	COG1764	response to oxidative stress
ACTEI_RS36265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACTEI_RS36270	COG0561	phosphatase activity
ACTEI_RS36275	COG0561	phosphatase activity
ACTEI_RS36285	COG1834	amidinotransferase
ACTEI_RS36290	COG1522	sequence-specific DNA binding
ACTEI_RS36310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACTEI_RS36315	COG3540	Alkaline phosphatase
ACTEI_RS36335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACTEI_RS36390	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACTEI_RS36390	COG0315	cyclic pyranopterin monophosphate synthase activity
ACTEI_RS36395	COG0315	cyclic pyranopterin monophosphate synthase activity
ACTEI_RS36400	COG5001	Diguanylate cyclase
ACTEI_RS36425	COG0305	Participates in initiation and elongation during chromosome replication
ACTEI_RS36435	COG0359	binds to the 23S rRNA
ACTEI_RS36440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACTEI_RS36450	COG0360	Binds together with S18 to 16S ribosomal RNA
ACTEI_RS36480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACTEI_RS36490	COG1695	Transcriptional regulator
ACTEI_RS36500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACTEI_RS36505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACTEI_RS36510	COG0617	tRNA 3'-terminal CCA addition
ACTEI_RS36525	COG2815	serine threonine protein kinase
ACTEI_RS36525	COG0515	serine threonine protein kinase
ACTEI_RS36530	COG1595	DNA-templated transcription, initiation
ACTEI_RS36545	COG3118	belongs to the thioredoxin family
ACTEI_RS36550	COG3409	Peptidoglycan-binding domain 1 protein
ACTEI_RS36550	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACTEI_RS36560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACTEI_RS36565	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACTEI_RS36580	COG1192	Involved in chromosome partitioning
ACTEI_RS36585	COG0357	Ribosomal RNA small subunit methyltransferase G
ACTEI_RS36600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACTEI_RS36605	COG0594	ribonuclease P activity
ACTEI_RS36610	COG0230	Belongs to the bacterial ribosomal protein bL34 family