locus-tag	class	description
CDG81_RS00010	COG0592	DNA-directed DNA polymerase activity
CDG81_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CDG81_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG81_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CDG81_RS00030	COG0187	DNA topoisomerase II activity
CDG81_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDG81_RS00070	COG0789	Transcriptional regulator
CDG81_RS00075	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDG81_RS00120	COG3764	Sortase (surface protein transpeptidase)
CDG81_RS00130	COG0569	domain protein
CDG81_RS00135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG81_RS00145	COG0515	serine threonine protein kinase
CDG81_RS00145	COG2815	serine threonine protein kinase
CDG81_RS00150	COG0515	serine threonine protein kinase
CDG81_RS00155	COG0768	penicillin binding
CDG81_RS00170	COG1716	ATPase activity
CDG81_RS00175	COG1716	ATPase activity
CDG81_RS00195	COG0586	Pfam SNARE associated Golgi protein
CDG81_RS00200	COG3973	AAA domain
CDG81_RS00205	COG0789	Transcriptional regulator
CDG81_RS00220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG81_RS00245	COG1253	flavin adenine dinucleotide binding
CDG81_RS00260	COG2807	transmembrane transport
CDG81_RS00265	COG1414	Transcriptional regulator
CDG81_RS00350	COG1309	transcriptional regulator
CDG81_RS00380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG81_RS00405	COG0667	Aldo Keto reductase
CDG81_RS00415	COG1690	Belongs to the RtcB family
CDG81_RS00430	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS00430	COG1216	Glycosyl transferase, family 2
CDG81_RS00445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG81_RS00450	COG3397	chitin binding
CDG81_RS00455	COG3360	Dodecin
CDG81_RS00475	COG3275	phosphorelay sensor kinase activity
CDG81_RS00495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_RS00500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDG81_RS00515	COG1528	Iron-storage protein
CDG81_RS00525	COG1011	Hydrolase
CDG81_RS00530	COG2814	Major facilitator Superfamily
CDG81_RS00540	COG2376	Dihydroxyacetone kinase
CDG81_RS00545	COG0698	ribose 5-phosphate isomerase
CDG81_RS00565	COG2259	Doxx family
CDG81_RS00620	COG2235	arginine
CDG81_RS00655	COG1271	oxidase subunit
CDG81_RS00660	COG1294	oxidase, subunit
CDG81_RS00665	COG4988	ABC transporter
CDG81_RS00685	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CDG81_RS00705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDG81_RS00715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_RS00720	COG0561	phosphatase activity
CDG81_RS00735	COG1216	Glycosyl transferase, family 2
CDG81_RS00745	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG81_RS00750	COG0442	prolyl-tRNA aminoacylation
CDG81_RS00775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDG81_RS00775	COG5479	isomerase activity
CDG81_RS00810	COG1216	Glycosyl transferase, family 2
CDG81_RS00835	COG2234	aminopeptidase activity
CDG81_RS00845	COG1131	(ABC) transporter
CDG81_RS00865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDG81_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG81_RS00890	COG4974	Belongs to the 'phage' integrase family
CDG81_RS00960	COG0183	Belongs to the thiolase family
CDG81_RS00965	COG0287	Prephenate dehydrogenase
CDG81_RS00975	COG0590	tRNA wobble adenosine to inosine editing
CDG81_RS00980	COG3237	CsbD-like
CDG81_RS01015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDG81_RS01020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG81_RS01035	COG0601	transmembrane transport
CDG81_RS01040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_RS01050	COG4608	Belongs to the ABC transporter superfamily
CDG81_RS01060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG81_RS01110	COG2610	gluconate transmembrane transporter activity
CDG81_RS01135	COG5650	phosphatidylinositol metabolic process
CDG81_RS01160	COG2197	response regulator
CDG81_RS01165	COG0657	acetylesterase activity
CDG81_RS01170	COG0431	NADPH-dependent FMN reductase
CDG81_RS01195	COG1131	(ABC) transporter
CDG81_RS01205	COG1902	pentaerythritol trinitrate reductase activity
CDG81_RS01220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG81_RS01225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG81_RS01240	COG0494	nUDIX hydrolase
CDG81_RS01245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDG81_RS01270	COG0071	Belongs to the small heat shock protein (HSP20) family
CDG81_RS01275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG81_RS01310	COG0003	Pfam Anion-transporting ATPase
CDG81_RS01335	COG1408	metallophosphoesterase
CDG81_RS01350	COG0823	Involved in the tonB-independent uptake of proteins
CDG81_RS01350	COG4946	Tricorn protease homolog
CDG81_RS01350	COG1506	peptidase
CDG81_RS01370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDG81_RS01375	COG1737	Transcriptional regulator
CDG81_RS01390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDG81_RS01395	COG3876	Protein conserved in bacteria
CDG81_RS01400	COG1472	Belongs to the glycosyl hydrolase 3 family
CDG81_RS01465	COG1111	helicase
CDG81_RS01465	COG1205	dead DEAH box helicase
CDG81_RS01470	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CDG81_RS01480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDG81_RS01480	COG1754	DNA topoisomerase type I activity
CDG81_RS01485	COG0470	DNA polymerase III
CDG81_RS01530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG81_RS01535	COG2027	D-alanyl-D-alanine carboxypeptidase
CDG81_RS01545	COG0037	tRNA processing
CDG81_RS01555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG81_RS01560	COG0302	gtp cyclohydrolase
CDG81_RS01600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDG81_RS01605	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CDG81_RS01610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDG81_RS01615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDG81_RS01635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_RS01640	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_RS01645	COG1120	ATPase activity
CDG81_RS01685	COG0471	metal ion transport
CDG81_RS01715	COG1511	domain protein
CDG81_RS01720	COG1121	(ABC) transporter
CDG81_RS01725	COG2226	methyltransferase
CDG81_RS01740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDG81_RS01755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDG81_RS01765	COG0546	phosphoglycolate phosphatase activity
CDG81_RS01770	COG0215	cysteine-tRNA ligase activity
CDG81_RS01790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG81_RS01795	COG1120	ATPase activity
CDG81_RS01805	COG3842	ATPase activity
CDG81_RS01810	COG1609	Transcriptional regulator
CDG81_RS01825	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDG81_RS01855	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CDG81_RS01870	COG0582	viral genome integration into host DNA
CDG81_RS01885	COG0305	Participates in initiation and elongation during chromosome replication
CDG81_RS02000	COG1857	crispr-associated protein
CDG81_RS02090	COG1063	alcohol dehydrogenase
CDG81_RS02095	COG2318	DinB family
CDG81_RS02110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG81_RS02115	COG2072	flavoprotein involved in K transport
CDG81_RS02190	COG0456	acetyltransferase
CDG81_RS02200	COG1917	Cupin 2, conserved barrel domain protein
CDG81_RS02210	COG3903	Transcriptional regulator
CDG81_RS02210	COG3629	intracellular signal transduction
CDG81_RS02240	COG2971	BadF BadG BcrA BcrD
CDG81_RS02245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG81_RS02250	COG2188	Transcriptional regulator
CDG81_RS02270	COG0352	thiamine-phosphate diphosphorylase activity
CDG81_RS02285	COG2022	thiamine diphosphate biosynthetic process
CDG81_RS02290	COG3311	Transcriptional regulator
CDG81_RS02295	COG1569	PIN domain
CDG81_RS02325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDG81_RS02350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG81_RS02365	COG0688	phosphatidylethanolamine metabolic process
CDG81_RS02385	COG1278	Cold shock
CDG81_RS02395	COG0459	protein refolding
CDG81_RS02400	COG3291	Pkd domain containing protein
CDG81_RS02400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CDG81_RS02420	COG1278	Cold shock
CDG81_RS02460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG81_RS02465	COG3311	Transcriptional regulator
CDG81_RS02470	COG1569	PIN domain
CDG81_RS02505	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_RS02515	COG1061	Type III restriction enzyme res subunit
CDG81_RS02525	COG1116	anion transmembrane transporter activity
CDG81_RS02530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG81_RS02550	COG2018	Roadblock/LC7 domain
CDG81_RS02580	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG81_RS02605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG81_RS02635	COG3304	Inner membrane component domain
CDG81_RS02640	COG0384	phenazine biosynthesis protein PhzF
CDG81_RS02680	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS02705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG81_RS02755	COG2814	Major facilitator Superfamily
CDG81_RS02760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG81_RS02770	COG2814	Major facilitator Superfamily
CDG81_RS02775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_RS02800	COG5002	protein histidine kinase activity
CDG81_RS02805	COG0745	RESPONSE REGULATOR receiver
CDG81_RS02835	COG1136	(ABC) transporter
CDG81_RS02835	COG0577	efflux transmembrane transporter activity
CDG81_RS02865	COG0259	pyridoxamine-phosphate oxidase activity
CDG81_RS02870	COG2017	converts alpha-aldose to the beta-anomer
CDG81_RS02875	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS02885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDG81_RS02885	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDG81_RS02895	COG1668	transmembrane transport
CDG81_RS02900	COG4152	abc transporter atp-binding protein
CDG81_RS02910	COG2130	NADP-dependent
CDG81_RS02920	COG1674	ftsk spoiiie
CDG81_RS02945	COG2267	carboxylic ester hydrolase activity
CDG81_RS02965	COG0596	Alpha beta hydrolase
CDG81_RS02970	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS02980	COG0667	Aldo Keto reductase
CDG81_RS02985	COG0346	lactoylglutathione lyase activity
CDG81_RS02995	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS03000	COG2205	protein histidine kinase activity
CDG81_RS03005	COG0745	RESPONSE REGULATOR receiver
CDG81_RS03010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDG81_RS03010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDG81_RS03040	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDG81_RS03040	COG1672	PFAM Archaeal ATPase
CDG81_RS03050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDG81_RS03065	COG1937	Protein conserved in bacteria
CDG81_RS03150	COG2130	NADP-dependent
CDG81_RS03155	COG0667	Aldo Keto reductase
CDG81_RS03160	COG1846	Transcriptional regulator
CDG81_RS03165	COG1309	transcriptional regulator
CDG81_RS03190	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDG81_RS03235	COG2197	response regulator
CDG81_RS03260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG81_RS03260	COG4651	solute:proton antiporter activity
CDG81_RS03320	COG1024	Enoyl-CoA hydratase
CDG81_RS03365	COG0582	viral genome integration into host DNA
CDG81_RS03400	COG0778	Nitroreductase
CDG81_RS03410	COG2205	protein histidine kinase activity
CDG81_RS03415	COG1349	DNA-binding transcription factor activity
CDG81_RS03425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG81_RS03430	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDG81_RS03430	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG81_RS03450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG81_RS03455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG81_RS03465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDG81_RS03500	COG0583	DNA-binding transcription factor activity
CDG81_RS03510	COG0800	Aldolase
CDG81_RS03515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG81_RS03520	COG3386	PFAM SMP-30 Gluconolaconase
CDG81_RS03525	COG2186	Transcriptional regulator
CDG81_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS03535	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_RS03550	COG2197	response regulator
CDG81_RS03560	COG1131	(ABC) transporter
CDG81_RS03590	COG1215	transferase activity, transferring glycosyl groups
CDG81_RS03595	COG1032	radical SAM domain protein
CDG81_RS03615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDG81_RS03630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG81_RS03640	COG0515	serine threonine protein kinase
CDG81_RS03645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG81_RS03645	COG2111	Na H antiporter
CDG81_RS03650	COG2111	Na H antiporter
CDG81_RS03655	COG1006	Multisubunit Na H antiporter MnhC subunit
CDG81_RS03660	COG0651	ATP synthesis coupled electron transport
CDG81_RS03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG81_RS03695	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CDG81_RS03695	COG1473	amidohydrolase
CDG81_RS03750	COG2321	neutral zinc metallopeptidase
CDG81_RS03760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDG81_RS03765	COG0424	maF-like protein
CDG81_RS03770	COG1301	dicarboxylic acid transport
CDG81_RS03775	COG4770	biotin carboxylase activity
CDG81_RS03805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDG81_RS03810	COG1349	DNA-binding transcription factor activity
CDG81_RS03815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDG81_RS03820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG81_RS03825	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG81_RS03840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_RS03890	COG0110	maltose O-acetyltransferase activity
CDG81_RS03895	COG3226	Transcriptional regulator
CDG81_RS03955	COG0483	inositol monophosphate 1-phosphatase activity
CDG81_RS03960	COG0745	RESPONSE REGULATOR receiver
CDG81_RS03965	COG2205	protein histidine kinase activity
CDG81_RS03980	COG1136	(ABC) transporter
CDG81_RS03990	COG3940	Belongs to the glycosyl hydrolase 43 family
CDG81_RS04075	COG1316	TRANSCRIPTIONal
CDG81_RS04080	COG1316	TRANSCRIPTIONal
CDG81_RS04100	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS04105	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS04135	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS04205	COG0778	Nitroreductase
CDG81_RS04205	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CDG81_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS04220	COG1994	Peptidase M50
CDG81_RS04260	COG1482	cell wall glycoprotein biosynthetic process
CDG81_RS04265	COG0531	amino acid
CDG81_RS04280	COG0745	RESPONSE REGULATOR receiver
CDG81_RS04285	COG5000	phosphorelay sensor kinase activity
CDG81_RS04285	COG5002	protein histidine kinase activity
CDG81_RS04290	COG5401	PFAM Sporulation and spore germination
CDG81_RS04300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDG81_RS04305	COG0653	protein targeting
CDG81_RS04335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_RS04360	COG1162	GTPase activity
CDG81_RS04365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG81_RS04390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDG81_RS04405	COG1597	lipid kinase activity
CDG81_RS04455	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDG81_RS04460	COG0281	malic enzyme
CDG81_RS04465	COG5001	Diguanylate cyclase
CDG81_RS04480	COG1174	glycine betaine transport
CDG81_RS04515	COG2986	histidine ammonia-lyase
CDG81_RS04520	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDG81_RS04535	COG1228	amidohydrolase
CDG81_RS04560	COG1063	alcohol dehydrogenase
CDG81_RS04580	COG0567	Dehydrogenase, E1 component
CDG81_RS04580	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDG81_RS04590	COG1132	(ABC) transporter
CDG81_RS04600	COG0671	phosphoesterase, PA-phosphatase related
CDG81_RS04735	COG0071	Belongs to the small heat shock protein (HSP20) family
CDG81_RS04760	COG0686	Belongs to the AlaDH PNT family
CDG81_RS04765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CDG81_RS04765	COG2508	Transcriptional regulator
CDG81_RS04770	COG0509	glycine decarboxylation via glycine cleavage system
CDG81_RS04775	COG1760	l-serine dehydratase
CDG81_RS04790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG81_RS04835	COG0277	FAD linked oxidase domain protein
CDG81_RS04840	COG0277	FAD linked oxidase domain protein
CDG81_RS04845	COG0247	lactate metabolic process
CDG81_RS04855	COG0183	Belongs to the thiolase family
CDG81_RS04860	COG1024	Enoyl-CoA hydratase
CDG81_RS04860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_RS04900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG81_RS04940	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_RS04975	COG0831	urea catabolic process
CDG81_RS04980	COG0832	Belongs to the urease beta subunit family
CDG81_RS04985	COG0804	urea catabolic process
CDG81_RS04995	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CDG81_RS05000	COG0829	nickel cation binding
CDG81_RS05015	COG4172	Belongs to the ABC transporter superfamily
CDG81_RS05020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_RS05030	COG4166	transmembrane transport
CDG81_RS05040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG81_RS05055	COG5001	Diguanylate cyclase
CDG81_RS05065	COG0477	Major facilitator Superfamily
CDG81_RS05085	COG0582	viral genome integration into host DNA
CDG81_RS05100	COG0018	arginyl-trna synthetase
CDG81_RS05105	COG0019	diaminopimelate decarboxylase activity
CDG81_RS05110	COG0460	homoserine dehydrogenase
CDG81_RS05115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG81_RS05120	COG0083	homoserine kinase activity
CDG81_RS05125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDG81_RS05130	COG0254	rRNA binding
CDG81_RS05135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDG81_RS05140	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG81_RS05155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDG81_RS05165	COG0356	it plays a direct role in the translocation of protons across the membrane
CDG81_RS05175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDG81_RS05180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDG81_RS05185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDG81_RS05190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDG81_RS05195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG81_RS05200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDG81_RS05250	COG1280	lysine exporter protein (LysE YggA)
CDG81_RS05260	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CDG81_RS05290	COG2376	Dihydroxyacetone kinase
CDG81_RS05295	COG1461	Dihydroxyacetone kinase
CDG81_RS05300	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CDG81_RS05325	COG2267	carboxylic ester hydrolase activity
CDG81_RS05350	COG0183	Belongs to the thiolase family
CDG81_RS05370	COG1846	Transcriptional regulator
CDG81_RS05400	COG0058	SHG alpha-glucan phosphorylase activity
CDG81_RS05405	COG1119	ATPase activity
CDG81_RS05420	COG1643	Atp-dependent helicase
CDG81_RS05425	COG1307	EDD domain protein, DegV family
CDG81_RS05435	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDG81_RS05460	COG0482	sulfurtransferase activity
CDG81_RS05475	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG81_RS05480	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS05505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG81_RS05535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_RS05545	COG0109	protoheme IX farnesyltransferase activity
CDG81_RS05560	COG1414	Transcriptional regulator
CDG81_RS05565	COG0149	triose-phosphate isomerase activity
CDG81_RS05575	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CDG81_RS05580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG81_RS05580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDG81_RS05585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG81_RS05610	COG3290	protein histidine kinase activity
CDG81_RS05615	COG4565	transcriptional regulatory protein
CDG81_RS05620	COG0456	acetyltransferase
CDG81_RS05675	COG2902	Dehydrogenase
CDG81_RS05680	COG0824	Thioesterase
CDG81_RS05690	COG0366	Alpha amylase catalytic
CDG81_RS05695	COG0366	Alpha amylase catalytic
CDG81_RS05705	COG0668	transmembrane transport
CDG81_RS05710	COG1505	serine-type exopeptidase activity
CDG81_RS05745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG81_RS05770	COG2814	Major facilitator Superfamily
CDG81_RS05790	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDG81_RS05795	COG0740	serine-type endopeptidase activity
CDG81_RS05800	COG0740	serine-type endopeptidase activity
CDG81_RS05805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDG81_RS05815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDG81_RS05820	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_RS05820	COG3773	Cell wall hydrolase
CDG81_RS05855	COG0525	valine-tRNA ligase activity
CDG81_RS05860	COG0285	dihydrofolate synthase activity
CDG81_RS05870	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG81_RS05875	COG0105	UTP biosynthetic process
CDG81_RS05885	COG1032	radical SAM domain protein
CDG81_RS05895	COG1530	ribonuclease E activity
CDG81_RS05895	COG1530	ribonuclease E activity
CDG81_RS05915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDG81_RS05920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDG81_RS05925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDG81_RS05935	COG0514	ATP-dependent DNA helicase (RecQ)
CDG81_RS05955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDG81_RS05960	COG0799	negative regulation of ribosome biogenesis
CDG81_RS05970	COG1307	EDD domain protein, DegV family
CDG81_RS05995	COG0268	Binds directly to 16S ribosomal RNA
CDG81_RS06020	COG3311	Transcriptional regulator
CDG81_RS06035	COG0481	GTPase activity
CDG81_RS06065	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS06070	COG1024	Enoyl-CoA hydratase
CDG81_RS06085	COG2732	(Barnase) inhibitor
CDG81_RS06100	COG4941	Belongs to the sigma-70 factor family
CDG81_RS06165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_RS06175	COG1420	regulation of RNA biosynthetic process
CDG81_RS06180	COG0484	heat shock protein binding
CDG81_RS06190	COG0537	adenosine 5'-monophosphoramidase activity
CDG81_RS06200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDG81_RS06215	COG1846	Transcriptional regulator
CDG81_RS06220	COG0038	chloride channel
CDG81_RS06225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG81_RS06240	COG1381	Involved in DNA repair and RecF pathway recombination
CDG81_RS06250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG81_RS06270	COG0423	glycine-tRNA ligase activity
CDG81_RS06280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CDG81_RS06310	COG4106	trans-aconitate 2-methyltransferase activity
CDG81_RS06380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_RS06420	COG4585	Histidine kinase
CDG81_RS06425	COG2197	response regulator
CDG81_RS06445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG81_RS06450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDG81_RS06470	COG3201	nicotinamide mononucleotide transporter
CDG81_RS06475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CDG81_RS06540	COG2119	membrane
CDG81_RS06545	COG3268	Saccharopine dehydrogenase
CDG81_RS06580	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDG81_RS06605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG81_RS06620	COG1940	carbohydrate kinase activity
CDG81_RS06625	COG0477	Major facilitator Superfamily
CDG81_RS06680	COG0557	exoribonuclease II activity
CDG81_RS06690	COG0435	Glutathione S-transferase
CDG81_RS06695	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDG81_RS06730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG81_RS06730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG81_RS06740	COG0174	glutamine synthetase
CDG81_RS06775	COG1595	DNA-templated transcription, initiation
CDG81_RS06805	COG1376	ErfK ybiS ycfS ynhG family protein
CDG81_RS06820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG81_RS06825	COG1214	PFAM Peptidase M22, glycoprotease
CDG81_RS06825	COG0456	acetyltransferase
CDG81_RS06835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG81_RS06850	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG81_RS06865	COG0129	dihydroxy-acid dehydratase activity
CDG81_RS06880	COG0440	acetolactate synthase activity
CDG81_RS06885	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDG81_RS06895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG81_RS06900	COG0473	3-isopropylmalate dehydrogenase activity
CDG81_RS06905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG81_RS06910	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG81_RS06920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG81_RS06950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG81_RS06955	COG0066	3-isopropylmalate dehydratase activity
CDG81_RS06960	COG0776	regulation of translation
CDG81_RS06975	COG1920	GTP binding
CDG81_RS06985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDG81_RS06990	COG0626	cystathionine gamma-synthase activity
CDG81_RS07005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_RS07030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDG81_RS07035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDG81_RS07040	COG1461	Dihydroxyacetone kinase
CDG81_RS07055	COG0742	ribosomal rna small subunit methyltransferase
CDG81_RS07060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDG81_RS07085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDG81_RS07090	COG0571	ribonuclease III activity
CDG81_RS07095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDG81_RS07100	COG0367	asparagine synthase
CDG81_RS07105	COG1072	(Pantothenic acid kinase))
CDG81_RS07115	COG1254	Belongs to the acylphosphatase family
CDG81_RS07120	COG1196	nuclear chromosome segregation
CDG81_RS07125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_RS07130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG81_RS07150	COG4133	protoheme IX ABC transporter activity
CDG81_RS07180	COG0228	four-way junction DNA binding
CDG81_RS07190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG81_RS07195	COG0336	Belongs to the RNA methyltransferase TrmD family
CDG81_RS07200	COG0335	large ribosomal subunit rRNA binding
CDG81_RS07205	COG0681	Belongs to the peptidase S26 family
CDG81_RS07210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG81_RS07220	COG0792	nuclease activity
CDG81_RS07240	COG1191	sigma factor activity
CDG81_RS07250	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG81_RS07255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDG81_RS07260	COG0528	UMP kinase activity
CDG81_RS07265	COG0233	cytoplasmic translational termination
CDG81_RS07270	COG0575	Belongs to the CDS family
CDG81_RS07290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDG81_RS07300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDG81_RS07305	COG0750	zinc metalloprotease
CDG81_RS07310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDG81_RS07320	COG0768	penicillin binding
CDG81_RS07335	COG1492	cobalamin metabolic process
CDG81_RS07340	COG2186	Transcriptional regulator
CDG81_RS07345	COG2807	transmembrane transport
CDG81_RS07390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDG81_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS07410	COG3420	alginic acid biosynthetic process
CDG81_RS07440	COG1881	PFAM PEBP family protein
CDG81_RS07450	COG1280	lysine exporter protein (LysE YggA)
CDG81_RS07460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG81_RS07510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG81_RS07510	COG1648	precorrin-2 dehydrogenase activity
CDG81_RS07520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_RS07555	COG3022	response to hydroperoxide
CDG81_RS07565	COG0442	prolyl-tRNA aminoacylation
CDG81_RS07575	COG0432	Pfam Uncharacterised protein family UPF0047
CDG81_RS07600	COG0779	Required for maturation of 30S ribosomal subunits
CDG81_RS07615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDG81_RS07620	COG1550	Protein conserved in bacteria
CDG81_RS07625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG81_RS07640	COG0242	peptide deformylase activity
CDG81_RS07645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG81_RS07665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDG81_RS07670	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG81_RS07710	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CDG81_RS07720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG81_RS07725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDG81_RS07735	COG0596	Alpha beta hydrolase
CDG81_RS07750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDG81_RS07760	COG1546	Belongs to the CinA family
CDG81_RS07760	COG1058	Belongs to the CinA family
CDG81_RS07765	COG1396	sequence-specific DNA binding
CDG81_RS07770	COG1842	Phage shock protein A
CDG81_RS07780	COG2233	PERMEase
CDG81_RS07785	COG1192	Involved in chromosome partitioning
CDG81_RS07790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG81_RS07800	COG1305	Transglutaminase-like
CDG81_RS07810	COG0714	Associated with various cellular activities
CDG81_RS07815	COG0275	rRNA processing
CDG81_RS07840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDG81_RS07845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDG81_RS07855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDG81_RS07860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG81_RS07875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDG81_RS07890	COG1799	cell septum assembly
CDG81_RS07900	COG3599	regulation of cell shape
CDG81_RS07910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG81_RS07915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDG81_RS07920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDG81_RS07935	COG0587	DNA-directed DNA polymerase activity
CDG81_RS07940	COG2124	cytochrome p450
CDG81_RS07970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG81_RS08010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_RS08030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG81_RS08035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDG81_RS08040	COG0131	Imidazoleglycerol-phosphate dehydratase
CDG81_RS08060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG81_RS08070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDG81_RS08075	COG0107	imidazoleglycerol-phosphate synthase activity
CDG81_RS08090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDG81_RS08100	COG0134	indole-3-glycerol-phosphate synthase activity
CDG81_RS08105	COG0133	tryptophan synthase activity
CDG81_RS08110	COG0159	tryptophan synthase activity
CDG81_RS08115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDG81_RS08120	COG1120	ATPase activity
CDG81_RS08125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_RS08130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDG81_RS08140	COG2186	Transcriptional regulator
CDG81_RS08160	COG1946	Acyl-CoA thioesterase
CDG81_RS08170	COG1280	lysine exporter protein (LysE YggA)
CDG81_RS08175	COG2027	D-alanyl-D-alanine carboxypeptidase
CDG81_RS08180	COG0586	Pfam SNARE associated Golgi protein
CDG81_RS08185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDG81_RS08190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDG81_RS08195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDG81_RS08205	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS08215	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS08220	COG5441	Belongs to the UPF0261 family
CDG81_RS08225	COG5564	TIM-barrel signal transduction protein
CDG81_RS08235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG81_RS08250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG81_RS08280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG81_RS08280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG81_RS08285	COG1802	Transcriptional regulator
CDG81_RS08300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDG81_RS08305	COG0022	dehydrogenase e1 component
CDG81_RS08310	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDG81_RS08330	COG3300	MHYT domain
CDG81_RS08330	COG5001	Diguanylate cyclase
CDG81_RS08390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDG81_RS08395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDG81_RS08395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDG81_RS08420	COG1764	response to oxidative stress
CDG81_RS08425	COG0640	Transcriptional regulator
CDG81_RS08430	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDG81_RS08440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDG81_RS08460	COG4311	Sarcosine oxidase, delta subunit
CDG81_RS08475	COG1414	Transcriptional regulator
CDG81_RS08485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDG81_RS08490	COG1414	Transcriptional regulator
CDG81_RS08515	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS08530	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS08540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDG81_RS08545	COG1070	Carbohydrate kinase
CDG81_RS08590	COG0395	ABC-type sugar transport system, permease component
CDG81_RS08655	COG2050	protein possibly involved in aromatic compounds catabolism
CDG81_RS08675	COG1122	ATPase activity
CDG81_RS08685	COG2226	methyltransferase
CDG81_RS08690	COG0539	negative regulation of cytoplasmic translation
CDG81_RS08715	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS08720	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_RS08730	COG1024	Enoyl-CoA hydratase
CDG81_RS08740	COG0583	DNA-binding transcription factor activity
CDG81_RS08780	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS08820	COG1011	Hydrolase
CDG81_RS08835	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_RS08840	COG3226	Transcriptional regulator
CDG81_RS08860	COG3757	hydrolase, family 25
CDG81_RS08860	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_RS08865	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS08870	COG2226	methyltransferase
CDG81_RS08890	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS08900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_RS08915	COG0662	Cupin 2, conserved barrel domain protein
CDG81_RS08950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG81_RS08965	COG1309	transcriptional regulator
CDG81_RS08970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDG81_RS08970	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDG81_RS08975	COG1013	pyruvate-flavodoxin oxidoreductase activity
CDG81_RS08995	COG0492	ferredoxin-NADP+ reductase activity
CDG81_RS09005	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS09015	COG1388	LysM domain
CDG81_RS09015	COG3858	chitin binding
CDG81_RS09025	COG2197	response regulator
CDG81_RS09040	COG2017	converts alpha-aldose to the beta-anomer
CDG81_RS09045	COG3250	beta-galactosidase activity
CDG81_RS09055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG81_RS09060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG81_RS09070	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG81_RS09135	COG1024	Enoyl-CoA hydratase
CDG81_RS09140	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_RS09150	COG0477	Major facilitator Superfamily
CDG81_RS09155	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS09180	COG1716	ATPase activity
CDG81_RS09195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDG81_RS09195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDG81_RS09225	COG3104	oligopeptide transport
CDG81_RS09245	COG3572	ergothioneine biosynthetic process
CDG81_RS09250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDG81_RS09255	COG0121	glutamine amidotransferase
CDG81_RS09260	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CDG81_RS09275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDG81_RS09310	COG2146	nitrite reductase [NAD(P)H] activity
CDG81_RS09310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_RS09315	COG2146	nitrite reductase [NAD(P)H] activity
CDG81_RS09315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_RS09320	COG0243	molybdopterin cofactor binding
CDG81_RS09325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDG81_RS09330	COG3883	PFAM NLP P60 protein
CDG81_RS09330	COG0791	NLP P60 protein
CDG81_RS09340	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDG81_RS09345	COG0346	lactoylglutathione lyase activity
CDG81_RS09350	COG0400	carboxylic ester hydrolase activity
CDG81_RS09360	COG0529	Catalyzes the synthesis of activated sulfate
CDG81_RS09365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG81_RS09370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG81_RS09380	COG3485	protocatechuate 3,4-dioxygenase
CDG81_RS09385	COG3485	protocatechuate 3,4-dioxygenase
CDG81_RS09390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDG81_RS09395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG81_RS09400	COG1414	Transcriptional regulator
CDG81_RS09405	COG1132	(ABC) transporter
CDG81_RS09410	COG2183	response to ionizing radiation
CDG81_RS09415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDG81_RS09435	COG1233	COG1233 Phytoene dehydrogenase and related
CDG81_RS09445	COG1657	PFAM Prenyltransferase squalene oxidase
CDG81_RS09465	COG0300	oxidoreductase activity
CDG81_RS09470	COG0697	spore germination
CDG81_RS09475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDG81_RS09485	COG1349	DNA-binding transcription factor activity
CDG81_RS09510	COG0589	response to stress
CDG81_RS09525	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG81_RS09535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CDG81_RS09725	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CDG81_RS09730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG81_RS09730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG81_RS09755	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS09765	COG1966	Carbon starvation protein
CDG81_RS09780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG81_RS09795	COG0484	heat shock protein binding
CDG81_RS09800	COG2807	transmembrane transport
CDG81_RS09810	COG0395	ABC-type sugar transport system, permease component
CDG81_RS09815	COG1175	transmembrane transport
CDG81_RS09825	COG2706	6-phosphogluconolactonase activity
CDG81_RS09830	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDG81_RS09840	COG1414	Transcriptional regulator
CDG81_RS09845	COG0251	oxidation-reduction process
CDG81_RS09865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDG81_RS09870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDG81_RS09875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_RS09880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDG81_RS09885	COG0072	phenylalanine-tRNA ligase activity
CDG81_RS09885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG81_RS09890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDG81_RS09895	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG81_RS09900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG81_RS09910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDG81_RS09920	COG0137	argininosuccinate synthase activity
CDG81_RS09925	COG0165	Argininosuccinate lyase
CDG81_RS09930	COG2094	Belongs to the DNA glycosylase MPG family
CDG81_RS09935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG81_RS09960	COG0647	UMP catabolic process
CDG81_RS09975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG81_RS10000	COG0504	CTP synthase activity
CDG81_RS10005	COG0494	nUDIX hydrolase
CDG81_RS10020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG81_RS10025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG81_RS10035	COG0475	glutathione-regulated potassium exporter activity
CDG81_RS10055	COG1160	GTP binding
CDG81_RS10060	COG0656	L-ascorbic acid biosynthetic process
CDG81_RS10070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDG81_RS10080	COG1324	tolerance protein
CDG81_RS10090	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDG81_RS10115	COG0070	glutamate synthase
CDG81_RS10115	COG0069	glutamate synthase activity
CDG81_RS10115	COG0067	glutamate synthase
CDG81_RS10135	COG0730	response to heat
CDG81_RS10140	COG0746	molybdenum cofactor guanylyltransferase activity
CDG81_RS10145	COG0714	Associated with various cellular activities
CDG81_RS10160	COG1285	pathogenesis
CDG81_RS10165	COG0247	lactate metabolic process
CDG81_RS10165	COG0277	FAD linked oxidase domain protein
CDG81_RS10175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDG81_RS10180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDG81_RS10225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDG81_RS10265	COG2186	Transcriptional regulator
CDG81_RS10275	COG1316	TRANSCRIPTIONal
CDG81_RS10295	COG0542	response to heat
CDG81_RS10320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG81_RS10325	COG1366	Belongs to the anti-sigma-factor antagonist family
CDG81_RS10335	COG2318	DinB family
CDG81_RS10355	COG0477	Major facilitator Superfamily
CDG81_RS10365	COG0039	L-malate dehydrogenase activity
CDG81_RS10390	COG1643	Atp-dependent helicase
CDG81_RS10400	COG0657	acetylesterase activity
CDG81_RS10460	COG2367	Beta-lactamase
CDG81_RS10495	COG4974	Belongs to the 'phage' integrase family
CDG81_RS10515	COG1472	Belongs to the glycosyl hydrolase 3 family
CDG81_RS10520	COG1609	Transcriptional regulator
CDG81_RS10530	COG0640	Transcriptional regulator
CDG81_RS10545	COG1472	Belongs to the glycosyl hydrolase 3 family
CDG81_RS10560	COG1073	alpha beta
CDG81_RS10585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG81_RS10605	COG0142	geranyltranstransferase activity
CDG81_RS10630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_RS10630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_RS10720	COG1309	transcriptional regulator
CDG81_RS10730	COG1819	glycosyl
CDG81_RS10740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDG81_RS10770	COG0406	alpha-ribazole phosphatase activity
CDG81_RS10775	COG1968	undecaprenyl-diphosphatase activity
CDG81_RS10780	COG0667	Aldo Keto reductase
CDG81_RS10785	COG0477	Major facilitator Superfamily
CDG81_RS10795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG81_RS10820	COG1131	(ABC) transporter
CDG81_RS10825	COG3559	Exporter of polyketide antibiotics
CDG81_RS10855	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS10905	COG0789	Transcriptional regulator
CDG81_RS10920	COG2814	Major facilitator Superfamily
CDG81_RS10925	COG1492	cobalamin metabolic process
CDG81_RS10930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG81_RS10950	COG0346	lactoylglutathione lyase activity
CDG81_RS10960	COG0437	4 iron, 4 sulfur cluster binding
CDG81_RS10965	COG3383	formate dehydrogenase (NAD+) activity
CDG81_RS10965	COG0243	molybdopterin cofactor binding
CDG81_RS10970	COG3383	formate dehydrogenase (NAD+) activity
CDG81_RS10970	COG0243	molybdopterin cofactor binding
CDG81_RS11020	COG1309	transcriptional regulator
CDG81_RS11025	COG0709	Synthesizes selenophosphate from selenide and ATP
CDG81_RS11040	COG1921	L-seryl-tRNASec selenium transferase activity
CDG81_RS11050	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDG81_RS11055	COG0542	response to heat
CDG81_RS11080	COG0702	epimerase
CDG81_RS11095	COG1278	Cold shock
CDG81_RS11100	COG3321	synthase
CDG81_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS11100	COG0604	alcohol dehydrogenase
CDG81_RS11105	COG4607	ABC-type enterochelin transport system periplasmic component
CDG81_RS11125	COG0517	IMP dehydrogenase activity
CDG81_RS11125	COG0617	tRNA 3'-terminal CCA addition
CDG81_RS11125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDG81_RS11145	COG0589	response to stress
CDG81_RS11155	COG0589	response to stress
CDG81_RS11160	COG0589	response to stress
CDG81_RS11165	COG0589	response to stress
CDG81_RS11190	COG2814	Major facilitator Superfamily
CDG81_RS11195	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CDG81_RS11235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_RS11240	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CDG81_RS11245	COG3433	isochorismatase activity
CDG81_RS11245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_RS11245	COG2226	methyltransferase
CDG81_RS11270	COG1228	amidohydrolase
CDG81_RS11275	COG3588	fructose-bisphosphate aldolase
CDG81_RS11285	COG3842	ATPase activity
CDG81_RS11295	COG0395	ABC-type sugar transport system, permease component
CDG81_RS11300	COG1175	transmembrane transport
CDG81_RS11310	COG5297	Belongs to the glycosyl hydrolase family 6
CDG81_RS11320	COG5297	Belongs to the glycosyl hydrolase family 6
CDG81_RS11330	COG2223	nitrite transmembrane transporter activity
CDG81_RS11340	COG1940	carbohydrate kinase activity
CDG81_RS11345	COG1129	ABC transporter
CDG81_RS11350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDG81_RS11355	COG4213	ABC transporter substrate-binding protein
CDG81_RS11360	COG0673	inositol 2-dehydrogenase activity
CDG81_RS11370	COG2133	pyrroloquinoline quinone binding
CDG81_RS11385	COG1082	Xylose isomerase domain protein TIM barrel
CDG81_RS11395	COG0084	hydrolase, TatD family'
CDG81_RS11420	COG0604	alcohol dehydrogenase
CDG81_RS11440	COG0488	(ABC) transporter
CDG81_RS11470	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CDG81_RS11475	COG0659	secondary active sulfate transmembrane transporter activity
CDG81_RS11480	COG0789	Transcriptional regulator
CDG81_RS11500	COG1278	Cold shock
CDG81_RS11520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDG81_RS11560	COG2267	carboxylic ester hydrolase activity
CDG81_RS11565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_RS11575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_RS11585	COG3279	Response regulator of the LytR AlgR family
CDG81_RS11590	COG3275	phosphorelay sensor kinase activity
CDG81_RS11635	COG2205	protein histidine kinase activity
CDG81_RS11665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG81_RS11670	COG1937	Protein conserved in bacteria
CDG81_RS11710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDG81_RS11715	COG3483	tryptophan 2,3-dioxygenase activity
CDG81_RS11735	COG0415	Belongs to the DNA photolyase family
CDG81_RS11755	COG0583	DNA-binding transcription factor activity
CDG81_RS11810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_RS11815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDG81_RS11820	COG0798	PFAM Bile acid sodium symporter
CDG81_RS11825	COG0640	Transcriptional regulator
CDG81_RS11870	COG1175	transmembrane transport
CDG81_RS11875	COG0395	ABC-type sugar transport system, permease component
CDG81_RS11885	COG0673	inositol 2-dehydrogenase activity
CDG81_RS11890	COG3842	ATPase activity
CDG81_RS11895	COG1609	Transcriptional regulator
CDG81_RS11910	COG1929	Belongs to the glycerate kinase type-1 family
CDG81_RS11925	COG2814	Major facilitator Superfamily
CDG81_RS11930	COG1609	Transcriptional regulator
CDG81_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS11940	COG3347	Dehydrogenase
CDG81_RS11945	COG1070	Carbohydrate kinase
CDG81_RS11950	COG0247	lactate metabolic process
CDG81_RS11955	COG1139	Iron-sulfur cluster binding protein
CDG81_RS11960	COG1556	Lactate utilization protein
CDG81_RS11975	COG0107	imidazoleglycerol-phosphate synthase activity
CDG81_RS12025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDG81_RS12035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG81_RS12040	COG1121	(ABC) transporter
CDG81_RS12050	COG2860	membrane
CDG81_RS12060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CDG81_RS12060	COG2308	Evidence 4 Homologs of previously reported genes of
CDG81_RS12095	COG0463	Glycosyl transferase, family 2
CDG81_RS12100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG81_RS12115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_RS12130	COG1131	(ABC) transporter
CDG81_RS12145	COG0667	Aldo Keto reductase
CDG81_RS12175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG81_RS12190	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDG81_RS12190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDG81_RS12210	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CDG81_RS12215	COG0516	GMP reductase activity
CDG81_RS12215	COG0517	IMP dehydrogenase activity
CDG81_RS12220	COG0302	gtp cyclohydrolase
CDG81_RS12225	COG0602	queuosine metabolic process
CDG81_RS12230	COG0720	synthase
CDG81_RS12265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_RS12270	COG1309	transcriptional regulator
CDG81_RS12290	COG2815	serine threonine protein kinase
CDG81_RS12290	COG0515	serine threonine protein kinase
CDG81_RS12425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_RS12430	COG1940	carbohydrate kinase activity
CDG81_RS12440	COG0726	polysaccharide deacetylase
CDG81_RS12450	COG3842	ATPase activity
CDG81_RS12455	COG0366	Alpha amylase catalytic
CDG81_RS12545	COG2608	mercury ion transmembrane transporter activity
CDG81_RS12550	COG2132	Multicopper oxidase
CDG81_RS12555	COG1937	Protein conserved in bacteria
CDG81_RS12595	COG1959	2 iron, 2 sulfur cluster binding
CDG81_RS12605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG81_RS12625	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDG81_RS12630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_RS12645	COG5522	Integral membrane protein (intg_mem_TP0381)
CDG81_RS12670	COG0702	epimerase
CDG81_RS12685	COG0477	Major facilitator Superfamily
CDG81_RS12695	COG4948	Mandelate Racemase Muconate Lactonizing
CDG81_RS12700	COG2146	nitrite reductase [NAD(P)H] activity
CDG81_RS12700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_RS12705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG81_RS12710	COG0243	molybdopterin cofactor binding
CDG81_RS12715	COG1169	isochorismate synthase
CDG81_RS12720	COG1902	pentaerythritol trinitrate reductase activity
CDG81_RS12735	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDG81_RS12740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_RS12750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG81_RS12790	COG0009	L-threonylcarbamoyladenylate synthase
CDG81_RS12820	COG3257	ureidoglycine aminohydrolase activity
CDG81_RS12835	COG1609	Transcriptional regulator
CDG81_RS12850	COG4608	Belongs to the ABC transporter superfamily
CDG81_RS12855	COG0444	Belongs to the ABC transporter superfamily
CDG81_RS12865	COG0601	transmembrane transport
CDG81_RS12870	COG0747	negative chemotaxis
CDG81_RS12875	COG3345	alpha-galactosidase
CDG81_RS12895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG81_RS12895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG81_RS12905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG81_RS12955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_RS12970	COG0326	Molecular chaperone. Has ATPase activity
CDG81_RS13000	COG0006	proline dipeptidase activity
CDG81_RS13065	COG1857	crispr-associated protein
CDG81_RS13100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_RS13105	COG1120	ATPase activity
CDG81_RS13130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG81_RS13135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG81_RS13145	COG2124	cytochrome p450
CDG81_RS13155	COG0667	Aldo Keto reductase
CDG81_RS13160	COG1819	glycosyl
CDG81_RS13165	COG2124	cytochrome p450
CDG81_RS13210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG81_RS13220	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDG81_RS13225	COG2124	cytochrome p450
CDG81_RS13255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDG81_RS13255	COG2070	2-Nitropropane dioxygenase
CDG81_RS13260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG81_RS13260	COG0300	oxidoreductase activity
CDG81_RS13260	COG3321	synthase
CDG81_RS13260	COG4221	oxidoreductase activity
CDG81_RS13320	COG0367	asparagine synthase
CDG81_RS13335	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG81_RS13435	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDG81_RS13445	COG1799	cell septum assembly
CDG81_RS13485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDG81_RS13505	COG2226	methyltransferase
CDG81_RS13525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDG81_RS13530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG81_RS13595	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_RS13645	COG5285	phytanoyl-CoA dioxygenase
CDG81_RS13675	COG1607	acyl-coa hydrolase
CDG81_RS13680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_RS13690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG81_RS13700	COG2124	cytochrome p450
CDG81_RS13715	COG1917	Cupin 2, conserved barrel domain protein
CDG81_RS13735	COG0527	aspartate kinase activity
CDG81_RS13800	COG5650	phosphatidylinositol metabolic process
CDG81_RS13955	COG0596	Alpha beta hydrolase
CDG81_RS13985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG81_RS14010	COG2270	Major facilitator Superfamily
CDG81_RS14020	COG0463	Glycosyl transferase, family 2
CDG81_RS14030	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CDG81_RS14035	COG3030	protein affecting phage T7 exclusion by the F plasmid
CDG81_RS14045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG81_RS14085	COG4552	Acetyltransferase involved in intracellular survival and related
CDG81_RS14125	COG0154	amidase activity
CDG81_RS14130	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CDG81_RS14135	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CDG81_RS14140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CDG81_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS14190	COG1222	aaa ATPase
CDG81_RS14220	COG1994	Peptidase M50
CDG81_RS14220	COG0517	IMP dehydrogenase activity
CDG81_RS14240	COG0140	phosphoribosyl-ATP diphosphatase activity
CDG81_RS14270	COG2018	Roadblock/LC7 domain
CDG81_RS14280	COG0215	cysteine-tRNA ligase activity
CDG81_RS14300	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDG81_RS14315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_RS14320	COG0601	transmembrane transport
CDG81_RS14330	COG2362	D-Aminopeptidase
CDG81_RS14355	COG0488	(ABC) transporter
CDG81_RS14370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_RS14385	COG2151	metal-sulfur cluster biosynthetic enzyme
CDG81_RS14400	COG0396	ATPase activity
CDG81_RS14445	COG1510	regulation of RNA biosynthetic process
CDG81_RS14475	COG0586	Pfam SNARE associated Golgi protein
CDG81_RS14490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG81_RS14495	COG0166	Belongs to the GPI family
CDG81_RS14510	COG0363	glucosamine-6-phosphate deaminase activity
CDG81_RS14520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG81_RS14530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDG81_RS14535	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CDG81_RS14610	COG0375	protein maturation
CDG81_RS14625	COG0298	carbon dioxide binding
CDG81_RS14655	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CDG81_RS14665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDG81_RS14675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDG81_RS14695	COG0210	DNA helicase
CDG81_RS14700	COG2815	serine threonine protein kinase
CDG81_RS14700	COG0515	serine threonine protein kinase
CDG81_RS14845	COG0149	triose-phosphate isomerase activity
CDG81_RS14850	COG0126	phosphoglycerate kinase activity
CDG81_RS14860	COG1481	regulation of sporulation
CDG81_RS14865	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CDG81_RS14870	COG1660	Displays ATPase and GTPase activities
CDG81_RS14875	COG0322	excinuclease ABC activity
CDG81_RS14885	COG0167	dihydroorotate dehydrogenase activity
CDG81_RS14895	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDG81_RS14900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_RS14900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG81_RS14925	COG1113	amino acid transport
CDG81_RS14930	COG0037	tRNA processing
CDG81_RS14930	COG0590	tRNA wobble adenosine to inosine editing
CDG81_RS14945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDG81_RS14970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG81_RS14980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG81_RS14990	COG1758	RNA polymerase activity
CDG81_RS14995	COG0194	GDP metabolic process
CDG81_RS15005	COG0284	orotidine-5'-phosphate decarboxylase activity
CDG81_RS15015	COG0505	Belongs to the CarA family
CDG81_RS15030	COG0540	Belongs to the ATCase OTCase family
CDG81_RS15045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDG81_RS15050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG81_RS15075	COG1070	Carbohydrate kinase
CDG81_RS15085	COG1349	DNA-binding transcription factor activity
CDG81_RS15090	COG1063	alcohol dehydrogenase
CDG81_RS15095	COG0395	ABC-type sugar transport system, permease component
CDG81_RS15100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDG81_RS15105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDG81_RS15110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDG81_RS15115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDG81_RS15125	COG2190	(PTS) system
CDG81_RS15130	COG2190	(PTS) system
CDG81_RS15130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDG81_RS15130	COG1263	PTS System
CDG81_RS15135	COG1263	PTS System
CDG81_RS15140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDG81_RS15145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDG81_RS15160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDG81_RS15205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG81_RS15220	COG0076	glutamate decarboxylase activity
CDG81_RS15270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG81_RS15275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG81_RS15280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDG81_RS15295	COG2255	four-way junction helicase activity
CDG81_RS15300	COG0632	four-way junction helicase activity
CDG81_RS15305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDG81_RS15320	COG0217	transcriptional regulatory protein
CDG81_RS15325	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CDG81_RS15330	COG1113	amino acid transport
CDG81_RS15345	COG1396	sequence-specific DNA binding
CDG81_RS15350	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CDG81_RS15405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_RS15415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDG81_RS15420	COG2353	YceI-like domain
CDG81_RS15430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDG81_RS15455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG81_RS15455	COG1017	nitric oxide dioxygenase activity
CDG81_RS15460	COG1959	2 iron, 2 sulfur cluster binding
CDG81_RS15465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDG81_RS15470	COG0277	FAD linked oxidase domain protein
CDG81_RS15475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CDG81_RS15490	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_RS15495	COG0506	proline dehydrogenase activity
CDG81_RS15540	COG1950	PFAM Membrane protein of
CDG81_RS15545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG81_RS15550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG81_RS15565	COG0673	inositol 2-dehydrogenase activity
CDG81_RS15570	COG2197	response regulator
CDG81_RS15575	COG4585	Histidine kinase
CDG81_RS15600	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS15605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG81_RS15610	COG1802	Transcriptional regulator
CDG81_RS15640	COG0693	protein deglycase activity
CDG81_RS15650	COG0579	oxidoreductase
CDG81_RS15665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG81_RS15725	COG5006	permease, DMT superfamily
CDG81_RS15740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG81_RS15750	COG3253	May function as heme-dependent peroxidase
CDG81_RS15760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDG81_RS15775	COG2197	response regulator
CDG81_RS15780	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CDG81_RS15785	COG0183	Belongs to the thiolase family
CDG81_RS15790	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG81_RS15790	COG1024	Enoyl-CoA hydratase
CDG81_RS15800	COG2205	protein histidine kinase activity
CDG81_RS15805	COG0745	RESPONSE REGULATOR receiver
CDG81_RS15810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDG81_RS15815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG81_RS15820	COG0531	amino acid
CDG81_RS15825	COG0569	domain protein
CDG81_RS15850	COG0756	dUTP diphosphatase activity
CDG81_RS15915	COG1490	D-aminoacyl-tRNA deacylase activity
CDG81_RS15945	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDG81_RS15955	COG1321	iron dependent repressor
CDG81_RS15960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CDG81_RS15965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG81_RS15975	COG2936	dipeptidyl-peptidase activity
CDG81_RS15990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG81_RS15995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDG81_RS16015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG81_RS16025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDG81_RS16030	COG1196	nuclear chromosome segregation
CDG81_RS16040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDG81_RS16045	COG1126	abc transporter atp-binding protein
CDG81_RS16050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDG81_RS16055	COG0765	amino acid transport
CDG81_RS16060	COG0765	amino acid transport
CDG81_RS16075	COG0800	Aldolase
CDG81_RS16090	COG2137	regulation of response to DNA damage stimulus
CDG81_RS16095	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDG81_RS16110	COG1201	RNA secondary structure unwinding
CDG81_RS16130	COG0142	geranyltranstransferase activity
CDG81_RS16140	COG2815	serine threonine protein kinase
CDG81_RS16140	COG0515	serine threonine protein kinase
CDG81_RS16145	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDG81_RS16175	COG0003	Pfam Anion-transporting ATPase
CDG81_RS16245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG81_RS16270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG81_RS16285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDG81_RS16300	COG0667	Aldo Keto reductase
CDG81_RS16330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDG81_RS16350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG81_RS16360	COG1090	epimerase
CDG81_RS16365	COG0321	lipoyl(octanoyl) transferase activity
CDG81_RS16390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG81_RS16430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG81_RS16435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG81_RS16435	COG0519	Catalyzes the synthesis of GMP from XMP
CDG81_RS16475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG81_RS16490	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDG81_RS16495	COG0019	diaminopimelate decarboxylase activity
CDG81_RS16500	COG3835	regulator
CDG81_RS16520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDG81_RS16525	COG0590	tRNA wobble adenosine to inosine editing
CDG81_RS16530	COG2252	PERMEase
CDG81_RS16565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_RS16570	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDG81_RS16600	COG0028	Belongs to the TPP enzyme family
CDG81_RS16635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDG81_RS16640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG81_RS16650	COG1234	tRNA 3'-trailer cleavage
CDG81_RS16655	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG81_RS16690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG81_RS16695	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDG81_RS16700	COG1335	isochorismatase
CDG81_RS16715	COG1268	BioY protein
CDG81_RS16720	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS16725	COG0183	Belongs to the thiolase family
CDG81_RS16730	COG1122	ATPase activity
CDG81_RS16760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG81_RS16805	COG0667	Aldo Keto reductase
CDG81_RS16815	COG1984	allophanate hydrolase subunit 2
CDG81_RS16820	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDG81_RS16825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDG81_RS16855	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS16865	COG0367	asparagine synthase
CDG81_RS16890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG81_RS16910	COG0583	DNA-binding transcription factor activity
CDG81_RS16915	COG2814	Major facilitator Superfamily
CDG81_RS16920	COG2226	methyltransferase
CDG81_RS17020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDG81_RS17030	COG0823	Involved in the tonB-independent uptake of proteins
CDG81_RS17035	COG1357	PFAM Pentapeptide repeats (8 copies)
CDG81_RS17050	COG3693	PFAM glycoside hydrolase, family 10
CDG81_RS17050	COG3509	depolymerase
CDG81_RS17070	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS17070	COG0604	alcohol dehydrogenase
CDG81_RS17070	COG3321	synthase
CDG81_RS17085	COG2197	response regulator
CDG81_RS17100	COG2226	methyltransferase
CDG81_RS17105	COG0604	alcohol dehydrogenase
CDG81_RS17105	COG3321	synthase
CDG81_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS17150	COG0477	Major facilitator Superfamily
CDG81_RS17165	COG1122	ATPase activity
CDG81_RS17170	COG2072	flavoprotein involved in K transport
CDG81_RS17180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG81_RS17195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDG81_RS17200	COG2177	Part of the ABC transporter FtsEX involved in
CDG81_RS17205	COG2884	Cell division ATP-binding protein ftsE
CDG81_RS17210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDG81_RS17235	COG1615	UPF0182 protein
CDG81_RS17260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG81_RS17290	COG0612	Peptidase, M16
CDG81_RS17320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG81_RS17390	COG2267	carboxylic ester hydrolase activity
CDG81_RS17420	COG0513	Belongs to the DEAD box helicase family
CDG81_RS17440	COG0613	PHP domain protein
CDG81_RS17455	COG0598	Magnesium transport protein CorA
CDG81_RS17475	COG1266	CAAX protease self-immunity
CDG81_RS17480	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG81_RS17505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG81_RS17585	COG2301	Belongs to the HpcH HpaI aldolase family
CDG81_RS17590	COG2239	Acts as a magnesium transporter
CDG81_RS17610	COG1595	DNA-templated transcription, initiation
CDG81_RS17615	COG5662	AntiSigma factor
CDG81_RS17620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG81_RS17625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDG81_RS17640	COG1024	Enoyl-CoA hydratase
CDG81_RS17645	COG2818	Glycosylase
CDG81_RS17675	COG1611	Belongs to the LOG family
CDG81_RS17680	COG1611	Belongs to the LOG family
CDG81_RS17685	COG0330	HflC and HflK could
CDG81_RS17695	COG2171	N-acyltransferase activity
CDG81_RS17715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_RS17740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_RS17765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_RS17775	COG0747	negative chemotaxis
CDG81_RS17780	COG1217	gtp-binding protein TYPA
CDG81_RS17795	COG0494	nUDIX hydrolase
CDG81_RS17800	COG3850	Histidine kinase
CDG81_RS17800	COG5002	protein histidine kinase activity
CDG81_RS17815	COG1131	(ABC) transporter
CDG81_RS17835	COG3842	ATPase activity
CDG81_RS17855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CDG81_RS17860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDG81_RS17865	COG0156	8-amino-7-oxononanoate synthase activity
CDG81_RS17920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDG81_RS17925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDG81_RS17930	COG2080	2 iron, 2 sulfur cluster binding
CDG81_RS17935	COG3708	Transcriptional regulator
CDG81_RS17935	COG2207	Transcriptional regulator
CDG81_RS18005	COG1518	maintenance of DNA repeat elements
CDG81_RS18010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG81_RS18080	COG0012	GTP binding
CDG81_RS18100	COG2169	Transcriptional regulator
CDG81_RS18100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG81_RS18110	COG0419	ATPase involved in DNA repair
CDG81_RS18115	COG0420	3'-5' exonuclease activity
CDG81_RS18125	COG1070	Carbohydrate kinase
CDG81_RS18135	COG1609	Transcriptional regulator
CDG81_RS18150	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDG81_RS18155	COG1129	ABC transporter
CDG81_RS18165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDG81_RS18175	COG1570	exodeoxyribonuclease VII activity
CDG81_RS18185	COG1722	exodeoxyribonuclease VII activity
CDG81_RS18200	COG0492	ferredoxin-NADP+ reductase activity
CDG81_RS18205	COG0114	fumarate hydratase activity
CDG81_RS18220	COG0517	IMP dehydrogenase activity
CDG81_RS18220	COG0516	GMP reductase activity
CDG81_RS18245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CDG81_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS18270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_RS18285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG81_RS18290	COG2423	ornithine cyclodeaminase activity
CDG81_RS18300	COG2197	response regulator
CDG81_RS18325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG81_RS18330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG81_RS18345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDG81_RS18355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG81_RS18370	COG2986	histidine ammonia-lyase
CDG81_RS18380	COG0583	DNA-binding transcription factor activity
CDG81_RS18385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG81_RS18405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CDG81_RS18440	COG1331	Highly conserved protein containing a thioredoxin domain
CDG81_RS18450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG81_RS18460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_RS18470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG81_RS18480	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CDG81_RS18505	COG2755	lipolytic protein G-D-S-L family
CDG81_RS18510	COG0183	Belongs to the thiolase family
CDG81_RS18530	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CDG81_RS18535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG81_RS18550	COG1252	NADH dehydrogenase
CDG81_RS18565	COG4608	Belongs to the ABC transporter superfamily
CDG81_RS18575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDG81_RS18580	COG0601	transmembrane transport
CDG81_RS18585	COG4166	transmembrane transport
CDG81_RS18605	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS18620	COG0148	phosphopyruvate hydratase activity
CDG81_RS18640	COG3956	TIGRFAM MazG family protein
CDG81_RS18755	COG0277	FAD linked oxidase domain protein
CDG81_RS18805	COG2133	pyrroloquinoline quinone binding
CDG81_RS18815	COG1366	Belongs to the anti-sigma-factor antagonist family
CDG81_RS18855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDG81_RS18860	COG0193	aminoacyl-tRNA hydrolase activity
CDG81_RS18865	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_RS18890	COG0318	PFAM AMP-dependent synthetase and ligase
CDG81_RS18895	COG0488	(ABC) transporter
CDG81_RS18900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDG81_RS18905	COG1464	Belongs to the NlpA lipoprotein family
CDG81_RS18910	COG2011	ABC-type metal ion transport system permease component
CDG81_RS18915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG81_RS18920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG81_RS18925	COG3583	domain protein
CDG81_RS18930	COG1652	LysM domain
CDG81_RS18935	COG0084	hydrolase, TatD family'
CDG81_RS18940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG81_RS18945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDG81_RS18950	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_RS18955	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_RS19015	COG2009	succinate dehydrogenase
CDG81_RS19030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG81_RS19040	COG1686	Belongs to the peptidase S11 family
CDG81_RS19045	COG1295	ribonuclease BN
CDG81_RS19050	COG0180	Tryptophanyl-tRNA synthetase
CDG81_RS19070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDG81_RS19075	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CDG81_RS19080	COG1404	Belongs to the peptidase S8 family
CDG81_RS19110	COG0708	Exodeoxyribonuclease III
CDG81_RS19120	COG2409	Drug exporters of the RND superfamily
CDG81_RS19145	COG2072	flavoprotein involved in K transport
CDG81_RS19155	COG1757	Na H antiporter
CDG81_RS19225	COG2409	Drug exporters of the RND superfamily
CDG81_RS19265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDG81_RS19315	COG0045	succinate-CoA ligase (ADP-forming) activity
CDG81_RS19325	COG0739	heme binding
CDG81_RS19335	COG1131	(ABC) transporter
CDG81_RS19340	COG3559	Exporter of polyketide antibiotics
CDG81_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS19380	COG0515	serine threonine protein kinase
CDG81_RS19385	COG0515	serine threonine protein kinase
CDG81_RS19390	COG0583	DNA-binding transcription factor activity
CDG81_RS19395	COG0697	spore germination
CDG81_RS19410	COG2197	response regulator
CDG81_RS19430	COG0519	Catalyzes the synthesis of GMP from XMP
CDG81_RS19430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG81_RS19440	COG0516	GMP reductase activity
CDG81_RS19480	COG0459	protein refolding
CDG81_RS19490	COG3540	Alkaline phosphatase
CDG81_RS19495	COG3540	Alkaline phosphatase
CDG81_RS19515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDG81_RS19520	COG0456	acetyltransferase
CDG81_RS19525	COG0456	acetyltransferase
CDG81_RS19525	COG1214	PFAM Peptidase M22, glycoprotease
CDG81_RS19530	COG3250	beta-galactosidase activity
CDG81_RS19535	COG4266	Belongs to the allantoicase family
CDG81_RS19540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDG81_RS19545	COG1929	Belongs to the glycerate kinase type-1 family
CDG81_RS19550	COG3960	tartronate-semialdehyde synthase activity
CDG81_RS19555	COG2084	Dehydrogenase
CDG81_RS19565	COG3622	Belongs to the hyi family
CDG81_RS19600	COG2233	PERMEase
CDG81_RS19625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDG81_RS19630	COG1414	Transcriptional regulator
CDG81_RS19715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG81_RS19725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG81_RS19765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG81_RS19770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG81_RS19775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDG81_RS19785	COG4842	Belongs to the WXG100 family
CDG81_RS19795	COG0443	Heat shock 70 kDa protein
CDG81_RS19800	COG1674	ftsk spoiiie
CDG81_RS19810	COG1404	Belongs to the peptidase S8 family
CDG81_RS19835	COG0203	ribosomal protein L17
CDG81_RS19840	COG0202	RNA polymerase activity
CDG81_RS19845	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDG81_RS19850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDG81_RS19855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDG81_RS19860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDG81_RS19865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDG81_RS19870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG81_RS19890	COG0200	Binds to the 23S rRNA
CDG81_RS19895	COG1841	ribosomal large subunit assembly
CDG81_RS19900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG81_RS19905	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDG81_RS19910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDG81_RS19915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG81_RS19920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDG81_RS19925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDG81_RS19930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDG81_RS19935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDG81_RS19940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDG81_RS19945	COG0255	Belongs to the universal ribosomal protein uL29 family
CDG81_RS19950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDG81_RS19955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDG81_RS19960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDG81_RS19965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG81_RS19970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDG81_RS19975	COG0089	rRNA binding
CDG81_RS19980	COG0088	Forms part of the polypeptide exit tunnel
CDG81_RS19985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDG81_RS19990	COG0051	transcription antitermination factor activity, RNA binding
CDG81_RS19995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDG81_RS20000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDG81_RS20005	COG0049	tRNA binding
CDG81_RS20010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDG81_RS20020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDG81_RS20025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_RS20035	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDG81_RS20040	COG0085	RNA polymerase activity
CDG81_RS20100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CDG81_RS20145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG81_RS20155	COG1127	ABC transporter
CDG81_RS20210	COG0222	ribosome binding
CDG81_RS20215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDG81_RS20230	COG0081	regulation of translation
CDG81_RS20235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDG81_RS20255	COG0436	Aminotransferase
CDG81_RS20265	COG2030	dehydratase
CDG81_RS20270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDG81_RS20320	COG2018	Roadblock/LC7 domain
CDG81_RS20330	COG3162	membrane
CDG81_RS20335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_RS20340	COG0596	Alpha beta hydrolase
CDG81_RS20360	COG4115	mRNA cleavage
CDG81_RS20365	COG2161	toxin-antitoxin pair type II binding
CDG81_RS20375	COG1666	GTP binding
CDG81_RS20385	COG0501	Belongs to the peptidase M48B family
CDG81_RS20395	COG1834	amidinotransferase
CDG81_RS20400	COG1522	sequence-specific DNA binding
CDG81_RS20410	COG0142	geranyltranstransferase activity
CDG81_RS20415	COG1007	ATP synthesis coupled electron transport
CDG81_RS20430	COG0713	ATP synthesis coupled electron transport
CDG81_RS20440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG81_RS20445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDG81_RS20450	COG1034	ATP synthesis coupled electron transport
CDG81_RS20465	COG0649	NAD binding
CDG81_RS20470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG81_RS20475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG81_RS20490	COG2226	methyltransferase
CDG81_RS20525	COG0308	aminopeptidase N
CDG81_RS20540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDG81_RS20545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CDG81_RS20585	COG0477	Major facilitator Superfamily
CDG81_RS20595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG81_RS20605	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDG81_RS20610	COG2814	Major facilitator Superfamily
CDG81_RS20615	COG0656	L-ascorbic acid biosynthetic process
CDG81_RS20625	COG0435	Glutathione S-transferase
CDG81_RS20630	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CDG81_RS20635	COG0159	tryptophan synthase activity
CDG81_RS20640	COG0133	tryptophan synthase activity
CDG81_RS20645	COG0134	indole-3-glycerol-phosphate synthase activity
CDG81_RS20650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG81_RS20655	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG81_RS20660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDG81_RS20665	COG2124	cytochrome p450
CDG81_RS20670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_RS20675	COG2197	response regulator
CDG81_RS20700	COG4585	Histidine kinase
CDG81_RS20715	COG0535	radical SAM domain protein
CDG81_RS20730	COG1959	2 iron, 2 sulfur cluster binding
CDG81_RS20735	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS20815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDG81_RS20825	COG0785	Cytochrome C biogenesis protein
CDG81_RS20830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDG81_RS20835	COG0406	alpha-ribazole phosphatase activity
CDG81_RS20840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDG81_RS20880	COG0181	hydroxymethylbilane synthase activity
CDG81_RS20885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CDG81_RS20890	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDG81_RS20925	COG5001	Diguanylate cyclase
CDG81_RS20955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDG81_RS20980	COG5002	protein histidine kinase activity
CDG81_RS20995	COG0438	transferase activity, transferring glycosyl groups
CDG81_RS21015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDG81_RS21065	COG2733	membrane
CDG81_RS21085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_RS21100	COG0598	Magnesium transport protein CorA
CDG81_RS21155	COG2608	mercury ion transmembrane transporter activity
CDG81_RS21180	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS21190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_RS21215	COG2814	Major facilitator Superfamily
CDG81_RS21220	COG0656	L-ascorbic acid biosynthetic process
CDG81_RS21225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG81_RS21235	COG1739	Uncharacterized protein family UPF0029
CDG81_RS21255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG81_RS21260	COG2151	metal-sulfur cluster biosynthetic enzyme
CDG81_RS21265	COG3396	Phenylacetate-CoA oxygenase
CDG81_RS21270	COG3460	Phenylacetate-CoA oxygenase
CDG81_RS21275	COG3396	Phenylacetate-CoA oxygenase
CDG81_RS21280	COG1012	belongs to the aldehyde dehydrogenase family
CDG81_RS21280	COG2030	dehydratase
CDG81_RS21300	COG0531	amino acid
CDG81_RS21305	COG0531	amino acid
CDG81_RS21310	COG1597	lipid kinase activity
CDG81_RS21320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDG81_RS21325	COG3573	Dehydrogenase
CDG81_RS21345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDG81_RS21365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG81_RS21370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDG81_RS21385	COG0367	asparagine synthase
CDG81_RS21395	COG1309	transcriptional regulator
CDG81_RS21405	COG2814	Major facilitator Superfamily
CDG81_RS21410	COG1942	4-Oxalocrotonate Tautomerase
CDG81_RS21435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG81_RS21450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG81_RS21485	COG0673	inositol 2-dehydrogenase activity
CDG81_RS21500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG81_RS21520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG81_RS21560	COG0494	nUDIX hydrolase
CDG81_RS21600	COG1316	TRANSCRIPTIONal
CDG81_RS21605	COG0704	Plays a role in the regulation of phosphate uptake
CDG81_RS21615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG81_RS21620	COG0581	inorganic phosphate transmembrane transporter activity
CDG81_RS21635	COG0456	acetyltransferase
CDG81_RS21645	COG0745	RESPONSE REGULATOR receiver
CDG81_RS21685	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CDG81_RS21705	COG0354	folic acid binding
CDG81_RS21740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDG81_RS21770	COG3387	PFAM Glycoside hydrolase 15-related
CDG81_RS21775	COG1063	alcohol dehydrogenase
CDG81_RS21825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG81_RS21840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDG81_RS21850	COG0360	Binds together with S18 to 16S ribosomal RNA
CDG81_RS21860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDG81_RS21865	COG0359	binds to the 23S rRNA
CDG81_RS21920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG81_RS21925	COG2814	Major facilitator Superfamily
CDG81_RS21935	COG4221	oxidoreductase activity
CDG81_RS21940	COG0402	S-adenosylhomocysteine deaminase activity
CDG81_RS21950	COG2197	response regulator
CDG81_RS21955	COG4585	Histidine kinase
CDG81_RS21960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG81_RS21975	COG1131	(ABC) transporter
CDG81_RS21980	COG0561	phosphatase activity
CDG81_RS21990	COG2197	response regulator
CDG81_RS21995	COG4585	Histidine kinase
CDG81_RS22020	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CDG81_RS22115	COG2375	cellular response to nickel ion
CDG81_RS22125	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CDG81_RS22140	COG0765	amino acid transport
CDG81_RS22145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDG81_RS22150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG81_RS22170	COG0022	dehydrogenase e1 component
CDG81_RS22175	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDG81_RS22200	COG1309	transcriptional regulator
CDG81_RS22215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDG81_RS22225	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDG81_RS22230	COG1595	DNA-templated transcription, initiation
CDG81_RS22250	COG1595	DNA-templated transcription, initiation
CDG81_RS22255	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CDG81_RS22270	COG0151	Belongs to the GarS family
CDG81_RS22280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG81_RS22295	COG4129	membrane
CDG81_RS22320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDG81_RS22335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG81_RS22360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG81_RS22360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG81_RS22405	COG2814	Major facilitator Superfamily
CDG81_RS22445	COG0542	response to heat
CDG81_RS22450	COG0702	epimerase
CDG81_RS22455	COG2353	YceI-like domain
CDG81_RS22460	COG0477	Major facilitator Superfamily
CDG81_RS22515	COG1295	ribonuclease BN
CDG81_RS22545	COG0789	Transcriptional regulator
CDG81_RS22550	COG0484	heat shock protein binding
CDG81_RS22555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDG81_RS22560	COG0443	Heat shock 70 kDa protein
CDG81_RS22570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG81_RS22575	COG3226	Transcriptional regulator
CDG81_RS22580	COG2076	Multidrug Resistance protein
CDG81_RS22640	COG0477	Major facilitator Superfamily
CDG81_RS22645	COG0717	Belongs to the dCTP deaminase family
CDG81_RS22655	COG0494	nUDIX hydrolase
CDG81_RS22660	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDG81_RS22685	COG0667	Aldo Keto reductase
CDG81_RS22710	COG1028	Short-chain dehydrogenase reductase Sdr
CDG81_RS22730	COG0385	Bile acid
CDG81_RS22760	COG0668	transmembrane transport
CDG81_RS22765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG81_RS22770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG81_RS22790	COG0789	Transcriptional regulator
CDG81_RS22805	COG1960	acyl-CoA dehydrogenase activity
CDG81_RS22820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDG81_RS22850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG81_RS22860	COG1309	transcriptional regulator
CDG81_RS22865	COG0745	RESPONSE REGULATOR receiver
CDG81_RS22890	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG81_RS22895	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG81_RS22900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG81_RS22940	COG3706	GGDEF domain
CDG81_RS22950	COG2197	response regulator
CDG81_RS22960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDG81_RS23010	COG0495	leucyl-tRNA aminoacylation
CDG81_RS23020	COG1678	Uncharacterized ACR, COG1678
CDG81_RS23030	COG0617	tRNA 3'-terminal CCA addition
CDG81_RS23055	COG0515	serine threonine protein kinase
CDG81_RS23055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG81_RS23060	COG1595	DNA-templated transcription, initiation
CDG81_RS23075	COG0492	ferredoxin-NADP+ reductase activity
CDG81_RS23075	COG3118	belongs to the thioredoxin family
CDG81_RS23080	COG3409	Peptidoglycan-binding domain 1 protein
CDG81_RS23080	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDG81_RS23090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG81_RS23095	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDG81_RS23105	COG1192	Involved in chromosome partitioning
CDG81_RS23110	COG0357	Ribosomal RNA small subunit methyltransferase G
CDG81_RS23125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDG81_RS23130	COG0594	ribonuclease P activity
CDG81_RS23135	COG0230	Belongs to the bacterial ribosomal protein bL34 family