locus-tag	class	description
AMIR_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMIR_RS00010	COG0592	DNA-directed DNA polymerase activity
AMIR_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AMIR_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMIR_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AMIR_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMIR_RS00055	COG2259	Doxx family
AMIR_RS00070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMIR_RS00075	COG0705	Rhomboid family
AMIR_RS00090	COG3764	Sortase (surface protein transpeptidase)
AMIR_RS00105	COG2815	serine threonine protein kinase
AMIR_RS00105	COG0515	serine threonine protein kinase
AMIR_RS00110	COG0515	serine threonine protein kinase
AMIR_RS00115	COG0768	penicillin binding
AMIR_RS00130	COG1716	ATPase activity
AMIR_RS00135	COG1716	ATPase activity
AMIR_RS00165	COG1309	transcriptional regulator
AMIR_RS00175	COG2211	Major facilitator Superfamily
AMIR_RS00180	COG0300	oxidoreductase activity
AMIR_RS00195	COG3281	Trehalose synthase
AMIR_RS00225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AMIR_RS00245	COG0405	Gamma-glutamyltransferase
AMIR_RS00275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMIR_RS00325	COG3275	phosphorelay sensor kinase activity
AMIR_RS00335	COG3279	Response regulator of the LytR AlgR family
AMIR_RS00345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMIR_RS00355	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMIR_RS00380	COG0584	glycerophosphoryl diester phosphodiesterase
AMIR_RS00395	COG0653	protein targeting
AMIR_RS00410	COG1528	Iron-storage protein
AMIR_RS00460	COG1271	oxidase subunit
AMIR_RS00465	COG1294	oxidase, subunit
AMIR_RS00475	COG4988	ABC transporter
AMIR_RS00490	COG0454	-acetyltransferase
AMIR_RS00550	COG1501	Belongs to the glycosyl hydrolase 31 family
AMIR_RS00585	COG0754	glutathionylspermidine amidase activity
AMIR_RS00590	COG3766	membrane
AMIR_RS00600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMIR_RS00605	COG0579	oxidoreductase
AMIR_RS00615	COG0561	phosphatase activity
AMIR_RS00625	COG0463	Glycosyl transferase, family 2
AMIR_RS00645	COG1216	Glycosyl transferase, family 2
AMIR_RS00670	COG1216	Glycosyl transferase, family 2
AMIR_RS00715	COG2234	aminopeptidase activity
AMIR_RS00725	COG0737	Belongs to the 5'-nucleotidase family
AMIR_RS00725	COG1525	nuclease
AMIR_RS00725	COG4085	toxin activity
AMIR_RS00745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMIR_RS00775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMIR_RS00800	COG1686	Belongs to the peptidase S11 family
AMIR_RS00805	COG4932	domain protein
AMIR_RS00805	COG5295	Hep Hag repeat protein
AMIR_RS00845	COG0183	Belongs to the thiolase family
AMIR_RS00860	COG0287	Prephenate dehydrogenase
AMIR_RS00865	COG1473	amidohydrolase
AMIR_RS00940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMIR_RS00965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMIR_RS01025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMIR_RS01030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMIR_RS01055	COG3903	Transcriptional regulator
AMIR_RS01055	COG3629	intracellular signal transduction
AMIR_RS01060	COG0747	negative chemotaxis
AMIR_RS01065	COG0601	transmembrane transport
AMIR_RS01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIR_RS01075	COG0444	Belongs to the ABC transporter superfamily
AMIR_RS01080	COG4608	Belongs to the ABC transporter superfamily
AMIR_RS01085	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMIR_RS01125	COG1070	Carbohydrate kinase
AMIR_RS01130	COG1278	Cold shock
AMIR_RS01145	COG1764	response to oxidative stress
AMIR_RS01155	COG0431	NADPH-dependent FMN reductase
AMIR_RS01200	COG1408	metallophosphoesterase
AMIR_RS01285	COG0592	DNA-directed DNA polymerase activity
AMIR_RS01290	COG2814	Major facilitator Superfamily
AMIR_RS01310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMIR_RS01325	COG0596	Alpha beta hydrolase
AMIR_RS01335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMIR_RS01340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMIR_RS01355	COG3844	kynureninase activity
AMIR_RS01365	COG1522	sequence-specific DNA binding
AMIR_RS01370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AMIR_RS01375	COG1737	Transcriptional regulator
AMIR_RS01390	COG3876	Protein conserved in bacteria
AMIR_RS01400	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIR_RS01445	COG1205	dead DEAH box helicase
AMIR_RS01445	COG1111	helicase
AMIR_RS01450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMIR_RS01480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMIR_RS01480	COG1754	DNA topoisomerase type I activity
AMIR_RS01490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMIR_RS01495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMIR_RS01515	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AMIR_RS01520	COG1120	ATPase activity
AMIR_RS01560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMIR_RS01570	COG2027	D-alanyl-D-alanine carboxypeptidase
AMIR_RS01580	COG0037	tRNA processing
AMIR_RS01585	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AMIR_RS01595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMIR_RS01600	COG0302	gtp cyclohydrolase
AMIR_RS01605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMIR_RS01610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMIR_RS01630	COG0649	NAD binding
AMIR_RS01655	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMIR_RS01660	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMIR_RS01665	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMIR_RS01675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMIR_RS01685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS01690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS01695	COG1120	ATPase activity
AMIR_RS01710	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AMIR_RS01720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMIR_RS01745	COG1194	a g-specific adenine glycosylase
AMIR_RS01760	COG1609	Transcriptional regulator
AMIR_RS01770	COG1653	transport
AMIR_RS01775	COG1175	transmembrane transport
AMIR_RS01780	COG3833	ABC-type maltose transport systems, permease component
AMIR_RS01785	COG3842	ATPase activity
AMIR_RS01795	COG1121	(ABC) transporter
AMIR_RS01800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMIR_RS01830	COG0215	cysteine-tRNA ligase activity
AMIR_RS01840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMIR_RS01845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMIR_RS01850	COG1329	Transcriptional regulator
AMIR_RS01870	COG4221	oxidoreductase activity
AMIR_RS01880	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AMIR_RS01915	COG2205	protein histidine kinase activity
AMIR_RS01920	COG0745	RESPONSE REGULATOR receiver
AMIR_RS01950	COG3629	intracellular signal transduction
AMIR_RS01950	COG3903	Transcriptional regulator
AMIR_RS01970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS01975	COG0583	DNA-binding transcription factor activity
AMIR_RS01985	COG1404	Belongs to the peptidase S8 family
AMIR_RS01990	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMIR_RS01995	COG4948	Mandelate Racemase Muconate Lactonizing
AMIR_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS02020	COG2186	Transcriptional regulator
AMIR_RS02025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMIR_RS02030	COG0395	ABC-type sugar transport system, permease component
AMIR_RS02035	COG1175	transmembrane transport
AMIR_RS02040	COG2182	Extracellular solute-binding protein
AMIR_RS02045	COG2188	Transcriptional regulator
AMIR_RS02050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMIR_RS02055	COG3384	dioxygenase
AMIR_RS02060	COG0352	thiamine-phosphate diphosphorylase activity
AMIR_RS02065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIR_RS02065	COG2022	thiamine diphosphate biosynthetic process
AMIR_RS02075	COG2022	thiamine diphosphate biosynthetic process
AMIR_RS02085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMIR_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS02140	COG0351	phosphomethylpyrimidine kinase
AMIR_RS02145	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMIR_RS02170	COG1802	Transcriptional regulator
AMIR_RS02180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMIR_RS02200	COG0688	phosphatidylethanolamine metabolic process
AMIR_RS02220	COG1278	Cold shock
AMIR_RS02230	COG0459	protein refolding
AMIR_RS02245	COG3142	Participates in the control of copper homeostasis
AMIR_RS02255	COG1175	transmembrane transport
AMIR_RS02260	COG0395	ABC-type sugar transport system, permease component
AMIR_RS02265	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMIR_RS02280	COG4948	Mandelate Racemase Muconate Lactonizing
AMIR_RS02315	COG2018	Roadblock/LC7 domain
AMIR_RS02355	COG0315	cyclic pyranopterin monophosphate synthase activity
AMIR_RS02355	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMIR_RS02365	COG1388	LysM domain
AMIR_RS02375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMIR_RS02380	COG1846	Transcriptional regulator
AMIR_RS02400	COG3304	Inner membrane component domain
AMIR_RS02425	COG1278	Cold shock
AMIR_RS02435	COG2814	Major facilitator Superfamily
AMIR_RS02460	COG2252	PERMEase
AMIR_RS02470	COG2814	Major facilitator Superfamily
AMIR_RS02485	COG0488	(ABC) transporter
AMIR_RS02500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMIR_RS02520	COG5492	domain, Protein
AMIR_RS02525	COG0259	pyridoxamine-phosphate oxidase activity
AMIR_RS02530	COG0829	nickel cation binding
AMIR_RS02540	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMIR_RS02550	COG0804	urea catabolic process
AMIR_RS02555	COG0832	Belongs to the urease beta subunit family
AMIR_RS02560	COG0831	urea catabolic process
AMIR_RS02585	COG2197	response regulator
AMIR_RS02615	COG1132	(ABC) transporter
AMIR_RS02620	COG1132	(ABC) transporter
AMIR_RS02630	COG1309	transcriptional regulator
AMIR_RS02635	COG0531	amino acid
AMIR_RS02640	COG2017	converts alpha-aldose to the beta-anomer
AMIR_RS02645	COG1228	amidohydrolase
AMIR_RS02650	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS02670	COG0415	Belongs to the DNA photolyase family
AMIR_RS02675	COG2197	response regulator
AMIR_RS02685	COG1668	transmembrane transport
AMIR_RS02690	COG4152	abc transporter atp-binding protein
AMIR_RS02715	COG0402	S-adenosylhomocysteine deaminase activity
AMIR_RS02720	COG2130	NADP-dependent
AMIR_RS02735	COG1674	ftsk spoiiie
AMIR_RS02760	COG2267	carboxylic ester hydrolase activity
AMIR_RS02765	COG0583	DNA-binding transcription factor activity
AMIR_RS02770	COG0384	phenazine biosynthesis protein PhzF
AMIR_RS02775	COG0583	DNA-binding transcription factor activity
AMIR_RS02780	COG0702	epimerase
AMIR_RS02785	COG1733	regulation of RNA biosynthetic process
AMIR_RS02820	COG2197	response regulator
AMIR_RS02830	COG4249	Peptidase C14 caspase catalytic subunit p20
AMIR_RS02830	COG2319	Wd-40 repeat
AMIR_RS02875	COG3209	COG3209 Rhs family protein
AMIR_RS02895	COG3903	Transcriptional regulator
AMIR_RS02895	COG3629	intracellular signal transduction
AMIR_RS02960	COG0482	sulfurtransferase activity
AMIR_RS02975	COG1104	cysteine desulfurase activity
AMIR_RS02980	COG1061	Type III restriction enzyme res subunit
AMIR_RS02985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMIR_RS03015	COG2197	response regulator
AMIR_RS03025	COG0778	Nitroreductase
AMIR_RS03030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMIR_RS03035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMIR_RS03045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMIR_RS03050	COG0588	phosphoglycerate mutase activity
AMIR_RS03075	COG2205	protein histidine kinase activity
AMIR_RS03080	COG0395	ABC-type sugar transport system, permease component
AMIR_RS03085	COG1175	transmembrane transport
AMIR_RS03090	COG1653	transport
AMIR_RS03100	COG1349	DNA-binding transcription factor activity
AMIR_RS03110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIR_RS03120	COG0315	cyclic pyranopterin monophosphate synthase activity
AMIR_RS03120	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMIR_RS03125	COG1970	mechanosensitive ion channel activity
AMIR_RS03140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMIR_RS03145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMIR_RS03155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIR_RS03185	COG0515	serine threonine protein kinase
AMIR_RS03185	COG2815	serine threonine protein kinase
AMIR_RS03220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIR_RS03225	COG0084	hydrolase, TatD family'
AMIR_RS03230	COG3583	domain protein
AMIR_RS03235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMIR_RS03240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMIR_RS03245	COG2011	ABC-type metal ion transport system permease component
AMIR_RS03255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMIR_RS03260	COG0488	(ABC) transporter
AMIR_RS03265	COG3599	regulation of cell shape
AMIR_RS03280	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS03285	COG0193	aminoacyl-tRNA hydrolase activity
AMIR_RS03305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMIR_RS03340	COG2133	pyrroloquinoline quinone binding
AMIR_RS03360	COG3956	TIGRFAM MazG family protein
AMIR_RS03365	COG4946	Tricorn protease homolog
AMIR_RS03365	COG0793	Belongs to the peptidase S41A family
AMIR_RS03380	COG0148	phosphopyruvate hydratase activity
AMIR_RS03405	COG4166	transmembrane transport
AMIR_RS03410	COG0601	transmembrane transport
AMIR_RS03415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIR_RS03425	COG4608	Belongs to the ABC transporter superfamily
AMIR_RS03450	COG0714	Associated with various cellular activities
AMIR_RS03520	COG0183	Belongs to the thiolase family
AMIR_RS03550	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AMIR_RS03560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMIR_RS03570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMIR_RS03585	COG1331	Highly conserved protein containing a thioredoxin domain
AMIR_RS03595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMIR_RS03610	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMIR_RS03620	COG1793	dna ligase
AMIR_RS03625	COG0114	fumarate hydratase activity
AMIR_RS03630	COG0492	ferredoxin-NADP+ reductase activity
AMIR_RS03650	COG1722	exodeoxyribonuclease VII activity
AMIR_RS03660	COG1570	exodeoxyribonuclease VII activity
AMIR_RS03690	COG0419	ATPase involved in DNA repair
AMIR_RS03705	COG0012	GTP binding
AMIR_RS03735	COG1051	belongs to the nudix hydrolase family
AMIR_RS03745	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMIR_RS03755	COG4149	molybdate abc transporter
AMIR_RS03760	COG3842	ATPase activity
AMIR_RS03775	COG1131	(ABC) transporter
AMIR_RS03795	COG0494	nUDIX hydrolase
AMIR_RS03800	COG0180	Tryptophanyl-tRNA synthetase
AMIR_RS03810	COG1217	gtp-binding protein TYPA
AMIR_RS03815	COG0747	negative chemotaxis
AMIR_RS03820	COG4166	transmembrane transport
AMIR_RS03840	COG4608	Belongs to the ABC transporter superfamily
AMIR_RS03845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMIR_RS03880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIR_RS03885	COG1611	Belongs to the LOG family
AMIR_RS03890	COG1611	Belongs to the LOG family
AMIR_RS03900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMIR_RS03920	COG0519	Catalyzes the synthesis of GMP from XMP
AMIR_RS03945	COG1024	Enoyl-CoA hydratase
AMIR_RS03950	COG3327	negative regulation of DNA-templated transcription, initiation
AMIR_RS03955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMIR_RS03965	COG2814	Major facilitator Superfamily
AMIR_RS03980	COG0297	glycogen (starch) synthase activity
AMIR_RS03985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMIR_RS04000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIR_RS04005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMIR_RS04025	COG2239	Acts as a magnesium transporter
AMIR_RS04030	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
AMIR_RS04090	COG0598	Magnesium transport protein CorA
AMIR_RS04125	COG0513	Belongs to the DEAD box helicase family
AMIR_RS04160	COG2267	carboxylic ester hydrolase activity
AMIR_RS04180	COG0243	molybdopterin cofactor binding
AMIR_RS04185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIR_RS04190	COG2223	nitrite transmembrane transporter activity
AMIR_RS04195	COG2146	nitrite reductase [NAD(P)H] activity
AMIR_RS04195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIR_RS04200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIR_RS04200	COG2146	nitrite reductase [NAD(P)H] activity
AMIR_RS04225	COG0745	RESPONSE REGULATOR receiver
AMIR_RS04230	COG2205	protein histidine kinase activity
AMIR_RS04265	COG0210	DNA helicase
AMIR_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS04285	COG0583	DNA-binding transcription factor activity
AMIR_RS04325	COG0612	Peptidase, M16
AMIR_RS04335	COG1846	Transcriptional regulator
AMIR_RS04335	COG1940	carbohydrate kinase activity
AMIR_RS04365	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMIR_RS04410	COG0431	NADPH-dependent FMN reductase
AMIR_RS04445	COG0791	NLP P60 protein
AMIR_RS04465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMIR_RS04495	COG3842	ATPase activity
AMIR_RS04520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMIR_RS04540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMIR_RS04540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMIR_RS04545	COG0174	glutamine synthetase
AMIR_RS04575	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMIR_RS04685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMIR_RS04715	COG1615	UPF0182 protein
AMIR_RS04745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMIR_RS04750	COG2884	Cell division ATP-binding protein ftsE
AMIR_RS04755	COG2177	Part of the ABC transporter FtsEX involved in
AMIR_RS04760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMIR_RS04765	COG2197	response regulator
AMIR_RS04770	COG4585	Histidine kinase
AMIR_RS04780	COG1643	Atp-dependent helicase
AMIR_RS04790	COG0454	-acetyltransferase
AMIR_RS04790	COG0456	acetyltransferase
AMIR_RS04795	COG2814	Major facilitator Superfamily
AMIR_RS04805	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AMIR_RS04815	COG0515	serine threonine protein kinase
AMIR_RS04815	COG2815	serine threonine protein kinase
AMIR_RS04880	COG1175	transmembrane transport
AMIR_RS04885	COG0395	ABC-type sugar transport system, permease component
AMIR_RS04895	COG3254	rhamnose metabolic process
AMIR_RS04900	COG1609	Transcriptional regulator
AMIR_RS04935	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AMIR_RS04940	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AMIR_RS04945	COG0235	Class ii aldolase
AMIR_RS04950	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AMIR_RS04960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMIR_RS04965	COG3830	Belongs to the UPF0237 family
AMIR_RS04965	COG0560	Phosphoserine phosphatase
AMIR_RS05020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AMIR_RS05030	COG1335	isochorismatase
AMIR_RS05035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMIR_RS05040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMIR_RS05075	COG1234	tRNA 3'-trailer cleavage
AMIR_RS05080	COG3386	PFAM SMP-30 Gluconolaconase
AMIR_RS05090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AMIR_RS05095	COG1234	tRNA 3'-trailer cleavage
AMIR_RS05115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMIR_RS05120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMIR_RS05140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS05145	COG2072	flavoprotein involved in K transport
AMIR_RS05150	COG0586	Pfam SNARE associated Golgi protein
AMIR_RS05200	COG2949	membrane
AMIR_RS05205	COG1316	TRANSCRIPTIONal
AMIR_RS05210	COG0751	glycine-tRNA ligase activity
AMIR_RS05210	COG0752	glycyl-tRNA synthetase alpha subunit
AMIR_RS05220	COG4213	ABC transporter substrate-binding protein
AMIR_RS05230	COG1278	Cold shock
AMIR_RS05240	COG3345	alpha-galactosidase
AMIR_RS05250	COG4279	zinc finger
AMIR_RS05255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMIR_RS05295	COG1376	ErfK ybiS ycfS ynhG family protein
AMIR_RS05300	COG0488	(ABC) transporter
AMIR_RS05310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMIR_RS05340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMIR_RS05340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMIR_RS05365	COG1846	Transcriptional regulator
AMIR_RS05370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMIR_RS05385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMIR_RS05385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMIR_RS05420	COG4106	trans-aconitate 2-methyltransferase activity
AMIR_RS05425	COG0506	proline dehydrogenase activity
AMIR_RS05430	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS05440	COG0706	membrane insertase activity
AMIR_RS05465	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS05515	COG0740	serine-type endopeptidase activity
AMIR_RS05520	COG0740	serine-type endopeptidase activity
AMIR_RS05610	COG1609	Transcriptional regulator
AMIR_RS05615	COG2223	nitrite transmembrane transporter activity
AMIR_RS05630	COG3336	cytochrome c oxidase
AMIR_RS05665	COG2902	Dehydrogenase
AMIR_RS05690	COG0366	Alpha amylase catalytic
AMIR_RS05700	COG0668	transmembrane transport
AMIR_RS05705	COG1505	serine-type exopeptidase activity
AMIR_RS05725	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AMIR_RS05735	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMIR_RS05765	COG4552	Acetyltransferase involved in intracellular survival and related
AMIR_RS05785	COG0583	DNA-binding transcription factor activity
AMIR_RS05790	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMIR_RS05795	COG0740	serine-type endopeptidase activity
AMIR_RS05800	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMIR_RS05815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMIR_RS05850	COG0525	valine-tRNA ligase activity
AMIR_RS05855	COG0285	dihydrofolate synthase activity
AMIR_RS05880	COG0105	UTP biosynthetic process
AMIR_RS05885	COG1131	(ABC) transporter
AMIR_RS05895	COG0842	Transport permease protein
AMIR_RS05915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMIR_RS05940	COG1530	ribonuclease E activity
AMIR_RS05940	COG1530	ribonuclease E activity
AMIR_RS05945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMIR_RS05950	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMIR_RS05955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMIR_RS05965	COG0477	Major facilitator Superfamily
AMIR_RS05980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMIR_RS05995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMIR_RS06000	COG0799	negative regulation of ribosome biogenesis
AMIR_RS06010	COG2755	lipolytic protein G-D-S-L family
AMIR_RS06015	COG1307	EDD domain protein, DegV family
AMIR_RS06020	COG1555	photosystem II stabilization
AMIR_RS06020	COG1596	polysaccharide export
AMIR_RS06050	COG0268	Binds directly to 16S ribosomal RNA
AMIR_RS06080	COG2308	Evidence 4 Homologs of previously reported genes of
AMIR_RS06090	COG1305	Transglutaminase-like
AMIR_RS06095	COG0481	GTPase activity
AMIR_RS06110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMIR_RS06130	COG0531	amino acid
AMIR_RS06140	COG0604	alcohol dehydrogenase
AMIR_RS06155	COG2732	(Barnase) inhibitor
AMIR_RS06175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIR_RS06180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AMIR_RS06210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIR_RS06225	COG0484	heat shock protein binding
AMIR_RS06245	COG0596	Alpha beta hydrolase
AMIR_RS06250	COG0537	adenosine 5'-monophosphoramidase activity
AMIR_RS06265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMIR_RS06285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMIR_RS06290	COG1381	Involved in DNA repair and RecF pathway recombination
AMIR_RS06295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMIR_RS06310	COG0701	Predicted permease
AMIR_RS06345	COG0423	glycine-tRNA ligase activity
AMIR_RS06370	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMIR_RS06380	COG3340	Belongs to the peptidase S51 family
AMIR_RS06385	COG1595	DNA-templated transcription, initiation
AMIR_RS06390	COG0358	DNA primase activity
AMIR_RS06410	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AMIR_RS06415	COG2188	Transcriptional regulator
AMIR_RS06425	COG0494	nUDIX hydrolase
AMIR_RS06435	COG2186	Transcriptional regulator
AMIR_RS06485	COG0582	viral genome integration into host DNA
AMIR_RS06510	COG4106	trans-aconitate 2-methyltransferase activity
AMIR_RS06520	COG1316	TRANSCRIPTIONal
AMIR_RS06540	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AMIR_RS06555	COG5001	Diguanylate cyclase
AMIR_RS06570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMIR_RS06575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMIR_RS06585	COG2084	Dehydrogenase
AMIR_RS06620	COG1132	(ABC) transporter
AMIR_RS06625	COG1132	(ABC) transporter
AMIR_RS06630	COG0515	serine threonine protein kinase
AMIR_RS06645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIR_RS06650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMIR_RS06655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMIR_RS06670	COG3201	nicotinamide mononucleotide transporter
AMIR_RS06675	COG1653	transport
AMIR_RS06685	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMIR_RS06720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMIR_RS06740	COG0321	lipoyl(octanoyl) transferase activity
AMIR_RS06755	COG0702	epimerase
AMIR_RS06770	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIR_RS06775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMIR_RS06800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMIR_RS06805	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AMIR_RS06820	COG0667	Aldo Keto reductase
AMIR_RS06855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMIR_RS06865	COG0204	Acyl-transferase
AMIR_RS06865	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS06870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMIR_RS06885	COG1845	cytochrome c oxidase, subunit III
AMIR_RS06890	COG2010	Cytochrome c
AMIR_RS06900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMIR_RS06930	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS06955	COG0003	Pfam Anion-transporting ATPase
AMIR_RS06965	COG1940	carbohydrate kinase activity
AMIR_RS06995	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMIR_RS07020	COG0142	geranyltranstransferase activity
AMIR_RS07030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMIR_RS07055	COG0442	prolyl-tRNA aminoacylation
AMIR_RS07085	COG1201	RNA secondary structure unwinding
AMIR_RS07095	COG0443	Heat shock 70 kDa protein
AMIR_RS07100	COG2814	Major facilitator Superfamily
AMIR_RS07110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMIR_RS07115	COG2137	regulation of response to DNA damage stimulus
AMIR_RS07125	COG0800	Aldolase
AMIR_RS07170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMIR_RS07175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMIR_RS07185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMIR_RS07195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMIR_RS07210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMIR_RS07215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMIR_RS07225	COG1196	nuclear chromosome segregation
AMIR_RS07235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMIR_RS07240	COG2358	TRAP transporter, solute receptor (TAXI family
AMIR_RS07245	COG0642	Histidine kinase
AMIR_RS07250	COG0745	RESPONSE REGULATOR receiver
AMIR_RS07255	COG1126	abc transporter atp-binding protein
AMIR_RS07265	COG0765	amino acid transport
AMIR_RS07270	COG0765	amino acid transport
AMIR_RS07300	COG1515	deoxyribonuclease V activity
AMIR_RS07305	COG1486	melibiose metabolic process
AMIR_RS07310	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMIR_RS07315	COG2936	dipeptidyl-peptidase activity
AMIR_RS07325	COG4946	Tricorn protease homolog
AMIR_RS07325	COG1506	peptidase
AMIR_RS07325	COG0823	Involved in the tonB-independent uptake of proteins
AMIR_RS07330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMIR_RS07335	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AMIR_RS07355	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMIR_RS07365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIR_RS07370	COG2188	Transcriptional regulator
AMIR_RS07390	COG1690	Belongs to the RtcB family
AMIR_RS07450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMIR_RS07460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMIR_RS07465	COG4948	Mandelate Racemase Muconate Lactonizing
AMIR_RS07495	COG1490	D-aminoacyl-tRNA deacylase activity
AMIR_RS07500	COG2890	protein-(glutamine-N5) methyltransferase activity
AMIR_RS07520	COG2313	pseudouridylate synthase activity
AMIR_RS07550	COG4214	carbohydrate transport
AMIR_RS07600	COG0756	dUTP diphosphatase activity
AMIR_RS07630	COG0569	domain protein
AMIR_RS07635	COG0531	amino acid
AMIR_RS07640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMIR_RS07645	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMIR_RS07655	COG0745	RESPONSE REGULATOR receiver
AMIR_RS07660	COG2205	protein histidine kinase activity
AMIR_RS07750	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIR_RS07750	COG1024	Enoyl-CoA hydratase
AMIR_RS07755	COG0183	Belongs to the thiolase family
AMIR_RS07775	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AMIR_RS07780	COG2197	response regulator
AMIR_RS07795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMIR_RS07800	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AMIR_RS07805	COG3253	May function as heme-dependent peroxidase
AMIR_RS07810	COG1404	Belongs to the peptidase S8 family
AMIR_RS07830	COG3220	belongs to the UPF0276 family
AMIR_RS07860	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMIR_RS07880	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS07885	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS07890	COG3285	dna ligase
AMIR_RS07890	COG1793	dna ligase
AMIR_RS07925	COG5006	permease, DMT superfamily
AMIR_RS07930	COG1793	dna ligase
AMIR_RS07950	COG0488	(ABC) transporter
AMIR_RS07960	COG2706	6-phosphogluconolactonase activity
AMIR_RS07965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMIR_RS07990	COG1316	TRANSCRIPTIONal
AMIR_RS08010	COG0653	protein targeting
AMIR_RS08025	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS08050	COG1309	transcriptional regulator
AMIR_RS08095	COG0475	glutathione-regulated potassium exporter activity
AMIR_RS08115	COG1160	GTP binding
AMIR_RS08120	COG2197	response regulator
AMIR_RS08125	COG4585	Histidine kinase
AMIR_RS08350	COG0328	RNA-DNA hybrid ribonuclease activity
AMIR_RS08365	COG3345	alpha-galactosidase
AMIR_RS08370	COG3629	intracellular signal transduction
AMIR_RS08370	COG3903	Transcriptional regulator
AMIR_RS08440	COG0601	transmembrane transport
AMIR_RS08445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIR_RS08450	COG0444	Belongs to the ABC transporter superfamily
AMIR_RS08480	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AMIR_RS08485	COG2318	DinB family
AMIR_RS08490	COG2255	four-way junction helicase activity
AMIR_RS08495	COG0632	four-way junction helicase activity
AMIR_RS08520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMIR_RS08525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMIR_RS08530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMIR_RS08535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMIR_RS08545	COG0124	histidyl-tRNA synthetase
AMIR_RS08605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMIR_RS08610	COG0439	Biotin carboxylase
AMIR_RS08635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMIR_RS08650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMIR_RS08655	COG2205	protein histidine kinase activity
AMIR_RS08660	COG0745	RESPONSE REGULATOR receiver
AMIR_RS08670	COG2372	response to copper ion
AMIR_RS08695	COG0673	inositol 2-dehydrogenase activity
AMIR_RS08710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMIR_RS08725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMIR_RS08765	COG2244	polysaccharide biosynthetic process
AMIR_RS08850	COG0667	Aldo Keto reductase
AMIR_RS08855	COG2226	methyltransferase
AMIR_RS08855	COG0596	Alpha beta hydrolase
AMIR_RS08855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMIR_RS08860	COG1024	Enoyl-CoA hydratase
AMIR_RS08880	COG1295	ribonuclease BN
AMIR_RS08895	COG1126	abc transporter atp-binding protein
AMIR_RS08900	COG0765	amino acid transport
AMIR_RS08910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMIR_RS08945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMIR_RS08965	COG0395	ABC-type sugar transport system, permease component
AMIR_RS08970	COG2723	6-phospho-beta-galactosidase activity
AMIR_RS08990	COG5416	Lipopolysaccharide assembly protein A domain
AMIR_RS08995	COG2319	Wd-40 repeat
AMIR_RS08995	COG4249	Peptidase C14 caspase catalytic subunit p20
AMIR_RS09000	COG1940	carbohydrate kinase activity
AMIR_RS09005	COG2115	Belongs to the xylose isomerase family
AMIR_RS09010	COG1070	Carbohydrate kinase
AMIR_RS09040	COG2207	Transcriptional regulator
AMIR_RS09040	COG3708	Transcriptional regulator
AMIR_RS09090	COG0640	Transcriptional regulator
AMIR_RS09130	COG0791	NLP P60 protein
AMIR_RS09150	COG1609	Transcriptional regulator
AMIR_RS09155	COG1609	Transcriptional regulator
AMIR_RS09160	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIR_RS09170	COG3458	cephalosporin-C deacetylase activity
AMIR_RS09195	COG4941	Belongs to the sigma-70 factor family
AMIR_RS09225	COG0492	ferredoxin-NADP+ reductase activity
AMIR_RS09230	COG1785	Belongs to the alkaline phosphatase family
AMIR_RS09245	COG3866	Pectate lyase
AMIR_RS09260	COG0395	ABC-type sugar transport system, permease component
AMIR_RS09270	COG4948	Mandelate Racemase Muconate Lactonizing
AMIR_RS09295	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS09300	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS09310	COG1879	ABC-type sugar transport system periplasmic component
AMIR_RS09325	COG3940	Belongs to the glycosyl hydrolase 43 family
AMIR_RS09335	COG1609	Transcriptional regulator
AMIR_RS09350	COG2160	L-arabinose isomerase activity
AMIR_RS09355	COG4213	ABC transporter substrate-binding protein
AMIR_RS09365	COG4214	carbohydrate transport
AMIR_RS09375	COG3401	FG-GAP repeat protein
AMIR_RS09390	COG1609	Transcriptional regulator
AMIR_RS09415	COG2356	endonuclease I
AMIR_RS09425	COG4585	Histidine kinase
AMIR_RS09445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMIR_RS09450	COG4715	Zinc finger, swim domain protein
AMIR_RS09455	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AMIR_RS09460	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AMIR_RS09465	COG0714	Associated with various cellular activities
AMIR_RS09470	COG3831	ATPase activity
AMIR_RS09475	COG3831	ATPase activity
AMIR_RS09480	COG3831	ATPase activity
AMIR_RS09485	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS09510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMIR_RS09525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMIR_RS09530	COG2326	polyphosphate kinase activity
AMIR_RS09535	COG2261	transglycosylase associated protein
AMIR_RS09610	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AMIR_RS09615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMIR_RS09620	COG2815	serine threonine protein kinase
AMIR_RS09620	COG0515	serine threonine protein kinase
AMIR_RS09630	COG2755	lipolytic protein G-D-S-L family
AMIR_RS09630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMIR_RS09640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMIR_RS09665	COG0395	ABC-type sugar transport system, permease component
AMIR_RS09675	COG0702	epimerase
AMIR_RS09685	COG0745	RESPONSE REGULATOR receiver
AMIR_RS09705	COG2197	response regulator
AMIR_RS09710	COG4585	Histidine kinase
AMIR_RS09720	COG1131	(ABC) transporter
AMIR_RS09780	COG0477	Major facilitator Superfamily
AMIR_RS09820	COG2124	cytochrome p450
AMIR_RS09825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMIR_RS09845	COG1846	Transcriptional regulator
AMIR_RS09865	COG2197	response regulator
AMIR_RS09885	COG2264	protein methyltransferase activity
AMIR_RS09915	COG0395	ABC-type sugar transport system, permease component
AMIR_RS09920	COG4209	transmembrane transport
AMIR_RS09930	COG1609	Transcriptional regulator
AMIR_RS09940	COG0542	response to heat
AMIR_RS09970	COG1011	Hydrolase
AMIR_RS09985	COG1295	ribonuclease BN
AMIR_RS09995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMIR_RS10000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AMIR_RS10015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMIR_RS10025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMIR_RS10040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMIR_RS10065	COG2197	response regulator
AMIR_RS10080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIR_RS10110	COG1595	DNA-templated transcription, initiation
AMIR_RS10140	COG1834	amidinotransferase
AMIR_RS10145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMIR_RS10155	COG3483	tryptophan 2,3-dioxygenase activity
AMIR_RS10175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIR_RS10190	COG1132	(ABC) transporter
AMIR_RS10220	COG2181	nitrate reductase activity
AMIR_RS10225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AMIR_RS10230	COG1140	nitrate reductase beta subunit
AMIR_RS10270	COG3250	beta-galactosidase activity
AMIR_RS10275	COG5297	Belongs to the glycosyl hydrolase family 6
AMIR_RS10280	COG1732	Glycine betaine
AMIR_RS10285	COG1174	glycine betaine transport
AMIR_RS10290	COG1125	glycine betaine transport
AMIR_RS10290	COG0517	IMP dehydrogenase activity
AMIR_RS10295	COG1174	glycine betaine transport
AMIR_RS10325	COG3842	ATPase activity
AMIR_RS10345	COG0590	tRNA wobble adenosine to inosine editing
AMIR_RS10355	COG3835	regulator
AMIR_RS10385	COG0492	ferredoxin-NADP+ reductase activity
AMIR_RS10395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMIR_RS10405	COG2340	Cysteine-rich secretory protein family
AMIR_RS10410	COG0531	amino acid
AMIR_RS10420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMIR_RS10435	COG2186	Transcriptional regulator
AMIR_RS10475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMIR_RS10490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMIR_RS10495	COG1560	Kdo2-lipid A biosynthetic process
AMIR_RS10500	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS10505	COG1051	belongs to the nudix hydrolase family
AMIR_RS10525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIR_RS10535	COG1953	Uracil, thiamine, allantoin
AMIR_RS10570	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AMIR_RS10575	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AMIR_RS10580	COG0217	transcriptional regulatory protein
AMIR_RS10595	COG1309	transcriptional regulator
AMIR_RS10600	COG0477	Major facilitator Superfamily
AMIR_RS10610	COG2124	cytochrome p450
AMIR_RS10645	COG3572	ergothioneine biosynthetic process
AMIR_RS10650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMIR_RS10660	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AMIR_RS10695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMIR_RS10720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMIR_RS10730	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS10735	COG3883	PFAM NLP P60 protein
AMIR_RS10735	COG0791	NLP P60 protein
AMIR_RS10750	COG0746	molybdenum cofactor guanylyltransferase activity
AMIR_RS10755	COG0500	methyltransferase
AMIR_RS10760	COG0714	Associated with various cellular activities
AMIR_RS10770	COG2304	oxidoreductase activity
AMIR_RS10785	COG5002	protein histidine kinase activity
AMIR_RS10840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMIR_RS10860	COG3012	SEC-C Motif Domain Protein
AMIR_RS10870	COG4733	cellulase activity
AMIR_RS10870	COG5297	Belongs to the glycosyl hydrolase family 6
AMIR_RS10875	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIR_RS10890	COG4209	transmembrane transport
AMIR_RS10895	COG0395	ABC-type sugar transport system, permease component
AMIR_RS10910	COG1324	tolerance protein
AMIR_RS10915	COG0789	Transcriptional regulator
AMIR_RS10930	COG0247	lactate metabolic process
AMIR_RS10930	COG0277	FAD linked oxidase domain protein
AMIR_RS10940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMIR_RS10945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMIR_RS10960	COG4221	oxidoreductase activity
AMIR_RS10990	COG5297	Belongs to the glycosyl hydrolase family 6
AMIR_RS10995	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AMIR_RS11020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMIR_RS11035	COG0215	cysteine-tRNA ligase activity
AMIR_RS11065	COG0745	RESPONSE REGULATOR receiver
AMIR_RS11070	COG0745	RESPONSE REGULATOR receiver
AMIR_RS11075	COG5002	protein histidine kinase activity
AMIR_RS11085	COG1410	methionine synthase
AMIR_RS11085	COG0646	methionine synthase
AMIR_RS11090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIR_RS11105	COG1902	pentaerythritol trinitrate reductase activity
AMIR_RS11105	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMIR_RS11120	COG0140	phosphoribosyl-ATP diphosphatase activity
AMIR_RS11125	COG0679	Auxin Efflux Carrier
AMIR_RS11145	COG1994	Peptidase M50
AMIR_RS11145	COG0517	IMP dehydrogenase activity
AMIR_RS11155	COG2197	response regulator
AMIR_RS11185	COG1222	aaa ATPase
AMIR_RS11190	COG2197	response regulator
AMIR_RS11195	COG4585	Histidine kinase
AMIR_RS11235	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMIR_RS11240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMIR_RS11245	COG4221	oxidoreductase activity
AMIR_RS11265	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMIR_RS11280	COG2378	regulation of single-species biofilm formation
AMIR_RS11290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMIR_RS11315	COG4552	Acetyltransferase involved in intracellular survival and related
AMIR_RS11345	COG3706	GGDEF domain
AMIR_RS11375	COG2357	RelA SpoT domain protein
AMIR_RS11395	COG1846	Transcriptional regulator
AMIR_RS11400	COG0714	Associated with various cellular activities
AMIR_RS11410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMIR_RS11420	COG1703	isobutyryl-CoA mutase activity
AMIR_RS11420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMIR_RS11420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMIR_RS11435	COG0187	DNA topoisomerase II activity
AMIR_RS11465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMIR_RS11490	COG3845	ABC transporter
AMIR_RS11510	COG2226	methyltransferase
AMIR_RS11520	COG1940	carbohydrate kinase activity
AMIR_RS11525	COG0673	inositol 2-dehydrogenase activity
AMIR_RS11535	COG0277	FAD linked oxidase domain protein
AMIR_RS11575	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIR_RS11580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS11600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMIR_RS11610	COG0745	RESPONSE REGULATOR receiver
AMIR_RS11620	COG0745	RESPONSE REGULATOR receiver
AMIR_RS11630	COG2201	protein-glutamate methylesterase activity
AMIR_RS11645	COG0835	chemotaxis
AMIR_RS11650	COG0784	Response regulator, receiver
AMIR_RS11650	COG2198	Histidine kinase
AMIR_RS11650	COG0643	Histidine kinase
AMIR_RS11665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMIR_RS11675	COG1987	bacterial-type flagellum assembly
AMIR_RS11680	COG1338	Plays a role in the flagellum-specific transport system
AMIR_RS11705	COG1360	Flagellar Motor Protein
AMIR_RS11710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMIR_RS11720	COG4786	Flagellar basal body rod
AMIR_RS11735	COG0741	lytic transglycosylase activity
AMIR_RS11745	COG1157	protein secretion by the type III secretion system
AMIR_RS11755	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMIR_RS11760	COG1766	The M ring may be actively involved in energy transduction
AMIR_RS11765	COG1677	Flagellar hook-basal body complex protein FliE
AMIR_RS11785	COG1516	flagellar protein fliS
AMIR_RS11810	COG4786	Flagellar basal body rod
AMIR_RS11810	COG1256	bacterial-type flagellum assembly
AMIR_RS11820	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AMIR_RS11825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AMIR_RS11855	COG5002	protein histidine kinase activity
AMIR_RS11865	COG0745	RESPONSE REGULATOR receiver
AMIR_RS11865	COG2205	protein histidine kinase activity
AMIR_RS11865	COG4191	Histidine kinase
AMIR_RS11880	COG2204	response regulator
AMIR_RS11905	COG1846	Transcriptional regulator
AMIR_RS11925	COG4251	negative regulation of phosphorylation
AMIR_RS11940	COG1522	sequence-specific DNA binding
AMIR_RS11945	COG2814	Major facilitator Superfamily
AMIR_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS11985	COG0326	Molecular chaperone. Has ATPase activity
AMIR_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS12040	COG1609	Transcriptional regulator
AMIR_RS12050	COG1175	transmembrane transport
AMIR_RS12055	COG0395	ABC-type sugar transport system, permease component
AMIR_RS12070	COG2197	response regulator
AMIR_RS12075	COG4585	Histidine kinase
AMIR_RS12105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMIR_RS12135	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS12160	COG0277	FAD linked oxidase domain protein
AMIR_RS12205	COG0420	3'-5' exonuclease activity
AMIR_RS12235	COG0604	alcohol dehydrogenase
AMIR_RS12255	COG2119	membrane
AMIR_RS12295	COG0747	negative chemotaxis
AMIR_RS12305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIR_RS12330	COG0745	RESPONSE REGULATOR receiver
AMIR_RS12335	COG2205	protein histidine kinase activity
AMIR_RS12355	COG1802	Transcriptional regulator
AMIR_RS12395	COG1335	isochorismatase
AMIR_RS12465	COG2124	cytochrome p450
AMIR_RS12485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIR_RS12495	COG1819	glycosyl
AMIR_RS12500	COG1132	(ABC) transporter
AMIR_RS12525	COG3795	YCII-related domain
AMIR_RS12530	COG4941	Belongs to the sigma-70 factor family
AMIR_RS12570	COG0714	Associated with various cellular activities
AMIR_RS12575	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AMIR_RS12610	COG0384	phenazine biosynthesis protein PhzF
AMIR_RS12625	COG3629	intracellular signal transduction
AMIR_RS12625	COG3903	Transcriptional regulator
AMIR_RS12665	COG0515	serine threonine protein kinase
AMIR_RS12680	COG1653	transport
AMIR_RS12685	COG2124	cytochrome p450
AMIR_RS12695	COG2814	Major facilitator Superfamily
AMIR_RS12705	COG4581	dead DEAH box helicase
AMIR_RS12745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMIR_RS12760	COG0477	Major facilitator Superfamily
AMIR_RS12770	COG1612	heme a metabolic process
AMIR_RS12870	COG0395	ABC-type sugar transport system, permease component
AMIR_RS12890	COG1609	Transcriptional regulator
AMIR_RS12900	COG1595	DNA-templated transcription, initiation
AMIR_RS12975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMIR_RS12980	COG0477	Major facilitator Superfamily
AMIR_RS13010	COG5650	phosphatidylinositol metabolic process
AMIR_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS13035	COG1309	transcriptional regulator
AMIR_RS13040	COG3384	dioxygenase
AMIR_RS13045	COG0702	epimerase
AMIR_RS13070	COG0488	(ABC) transporter
AMIR_RS13085	COG0640	Transcriptional regulator
AMIR_RS13090	COG0346	lactoylglutathione lyase activity
AMIR_RS13115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS13125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIR_RS13145	COG2205	protein histidine kinase activity
AMIR_RS13155	COG1253	flavin adenine dinucleotide binding
AMIR_RS13165	COG0604	alcohol dehydrogenase
AMIR_RS13175	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMIR_RS13175	COG2080	2 iron, 2 sulfur cluster binding
AMIR_RS13215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIR_RS13225	COG2376	Dihydroxyacetone kinase
AMIR_RS13230	COG0698	ribose 5-phosphate isomerase
AMIR_RS13235	COG0149	triose-phosphate isomerase activity
AMIR_RS13240	COG1082	Xylose isomerase domain protein TIM barrel
AMIR_RS13245	COG2084	Dehydrogenase
AMIR_RS13265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMIR_RS13300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIR_RS13300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIR_RS13310	COG1834	amidinotransferase
AMIR_RS13325	COG0475	glutathione-regulated potassium exporter activity
AMIR_RS13330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMIR_RS13380	COG1131	(ABC) transporter
AMIR_RS13400	COG0477	Major facilitator Superfamily
AMIR_RS13430	COG2267	carboxylic ester hydrolase activity
AMIR_RS13445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS13465	COG1509	lysine 2,3-aminomutase activity
AMIR_RS13490	COG1136	(ABC) transporter
AMIR_RS13525	COG4122	O-methyltransferase activity
AMIR_RS13540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS13545	COG1120	ATPase activity
AMIR_RS13590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMIR_RS13605	COG1120	ATPase activity
AMIR_RS13610	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS13615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS13620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMIR_RS13625	COG2375	cellular response to nickel ion
AMIR_RS13630	COG3433	isochorismatase activity
AMIR_RS13630	COG1535	isochorismatase
AMIR_RS13635	COG3433	isochorismatase activity
AMIR_RS13635	COG1535	isochorismatase
AMIR_RS13640	COG1021	2,3-dihydroxybenzoate-AMP ligase
AMIR_RS13645	COG1169	isochorismate synthase
AMIR_RS13650	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS13660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS13665	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMIR_RS13675	COG3655	Transcriptional regulator
AMIR_RS13690	COG4585	Histidine kinase
AMIR_RS13695	COG2197	response regulator
AMIR_RS13710	COG0148	phosphopyruvate hydratase activity
AMIR_RS13725	COG4152	abc transporter atp-binding protein
AMIR_RS13730	COG1668	transmembrane transport
AMIR_RS13785	COG0477	Major facilitator Superfamily
AMIR_RS13795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMIR_RS13800	COG2197	response regulator
AMIR_RS13810	COG1136	(ABC) transporter
AMIR_RS13810	COG0577	efflux transmembrane transporter activity
AMIR_RS13885	COG0456	acetyltransferase
AMIR_RS13890	COG1309	transcriptional regulator
AMIR_RS13895	COG1132	(ABC) transporter
AMIR_RS13910	COG0738	Major facilitator superfamily
AMIR_RS13920	COG0583	DNA-binding transcription factor activity
AMIR_RS13925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMIR_RS13935	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS13955	COG2409	Drug exporters of the RND superfamily
AMIR_RS14060	COG2197	response regulator
AMIR_RS14105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMIR_RS14110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMIR_RS14125	COG1131	(ABC) transporter
AMIR_RS14135	COG3321	synthase
AMIR_RS14135	COG0604	alcohol dehydrogenase
AMIR_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS14165	COG1653	transport
AMIR_RS14175	COG3833	ABC-type maltose transport systems, permease component
AMIR_RS14190	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIR_RS14200	COG0596	Alpha beta hydrolase
AMIR_RS14235	COG0028	Belongs to the TPP enzyme family
AMIR_RS14240	COG1473	amidohydrolase
AMIR_RS14245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS14260	COG1177	transmembrane transport
AMIR_RS14265	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMIR_RS14270	COG3842	ATPase activity
AMIR_RS14280	COG4221	oxidoreductase activity
AMIR_RS14300	COG1309	transcriptional regulator
AMIR_RS14375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS14380	COG1120	ATPase activity
AMIR_RS14415	COG0135	phosphoribosylanthranilate isomerase activity
AMIR_RS14435	COG2076	Multidrug Resistance protein
AMIR_RS14480	COG0642	Histidine kinase
AMIR_RS14490	COG0402	S-adenosylhomocysteine deaminase activity
AMIR_RS14495	COG1309	transcriptional regulator
AMIR_RS14550	COG3831	ATPase activity
AMIR_RS14555	COG4251	negative regulation of phosphorylation
AMIR_RS14565	COG0784	Response regulator, receiver
AMIR_RS14585	COG1733	regulation of RNA biosynthetic process
AMIR_RS14590	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS14600	COG0395	ABC-type sugar transport system, permease component
AMIR_RS14630	COG3629	intracellular signal transduction
AMIR_RS14630	COG3903	Transcriptional regulator
AMIR_RS14670	COG1222	aaa ATPase
AMIR_RS14770	COG3629	intracellular signal transduction
AMIR_RS14770	COG3903	Transcriptional regulator
AMIR_RS14815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMIR_RS14830	COG3831	ATPase activity
AMIR_RS14835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMIR_RS14865	COG0673	inositol 2-dehydrogenase activity
AMIR_RS14880	COG0494	nUDIX hydrolase
AMIR_RS14885	COG1309	transcriptional regulator
AMIR_RS14915	COG2182	Extracellular solute-binding protein
AMIR_RS14920	COG1175	transmembrane transport
AMIR_RS14925	COG0395	ABC-type sugar transport system, permease component
AMIR_RS14930	COG1501	Belongs to the glycosyl hydrolase 31 family
AMIR_RS14940	COG1609	Transcriptional regulator
AMIR_RS14970	COG4106	trans-aconitate 2-methyltransferase activity
AMIR_RS14990	COG2318	DinB family
AMIR_RS14995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMIR_RS15010	COG1309	transcriptional regulator
AMIR_RS15020	COG0789	Transcriptional regulator
AMIR_RS15025	COG2197	response regulator
AMIR_RS15035	COG1136	(ABC) transporter
AMIR_RS15035	COG0577	efflux transmembrane transporter activity
AMIR_RS15040	COG0577	efflux transmembrane transporter activity
AMIR_RS15040	COG1136	(ABC) transporter
AMIR_RS15050	COG0366	Alpha amylase catalytic
AMIR_RS15085	COG2375	cellular response to nickel ion
AMIR_RS15110	COG3831	ATPase activity
AMIR_RS15120	COG0483	inositol monophosphate 1-phosphatase activity
AMIR_RS15125	COG1132	(ABC) transporter
AMIR_RS15130	COG1132	(ABC) transporter
AMIR_RS15180	COG1556	Lactate utilization protein
AMIR_RS15185	COG1139	Iron-sulfur cluster binding protein
AMIR_RS15190	COG0247	lactate metabolic process
AMIR_RS15195	COG2188	Transcriptional regulator
AMIR_RS15210	COG1129	ABC transporter
AMIR_RS15220	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS15235	COG3347	Dehydrogenase
AMIR_RS15240	COG1070	Carbohydrate kinase
AMIR_RS15250	COG0402	S-adenosylhomocysteine deaminase activity
AMIR_RS15260	COG0583	DNA-binding transcription factor activity
AMIR_RS15270	COG3851	Histidine kinase
AMIR_RS15280	COG1595	DNA-templated transcription, initiation
AMIR_RS15295	COG2124	cytochrome p450
AMIR_RS15335	COG0601	transmembrane transport
AMIR_RS15340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIR_RS15345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMIR_RS15355	COG0367	asparagine synthase
AMIR_RS15375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMIR_RS15380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMIR_RS15385	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS15390	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AMIR_RS15430	COG3293	Transposase
AMIR_RS15465	COG2814	Major facilitator Superfamily
AMIR_RS15505	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMIR_RS15510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMIR_RS15525	COG3345	alpha-galactosidase
AMIR_RS15540	COG0644	oxidoreductase
AMIR_RS15545	COG0156	8-amino-7-oxononanoate synthase activity
AMIR_RS15585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMIR_RS15590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS15625	COG0656	L-ascorbic acid biosynthetic process
AMIR_RS15630	COG0583	DNA-binding transcription factor activity
AMIR_RS15645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMIR_RS15655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMIR_RS15660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMIR_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS15700	COG1063	alcohol dehydrogenase
AMIR_RS15710	COG0659	secondary active sulfate transmembrane transporter activity
AMIR_RS15750	COG1408	metallophosphoesterase
AMIR_RS15775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMIR_RS15775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMIR_RS15780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMIR_RS15790	COG2856	Zn peptidase
AMIR_RS15800	COG2409	Drug exporters of the RND superfamily
AMIR_RS15815	COG1024	Enoyl-CoA hydratase
AMIR_RS15850	COG1309	transcriptional regulator
AMIR_RS15860	COG1132	(ABC) transporter
AMIR_RS15865	COG0475	glutathione-regulated potassium exporter activity
AMIR_RS15890	COG0604	alcohol dehydrogenase
AMIR_RS15890	COG3321	synthase
AMIR_RS15900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMIR_RS15915	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIR_RS15920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIR_RS15950	COG3795	YCII-related domain
AMIR_RS15965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMIR_RS15980	COG0604	alcohol dehydrogenase
AMIR_RS15980	COG3321	synthase
AMIR_RS15985	COG0604	alcohol dehydrogenase
AMIR_RS15985	COG3321	synthase
AMIR_RS15995	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS16010	COG2124	cytochrome p450
AMIR_RS16010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMIR_RS16015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMIR_RS16015	COG2124	cytochrome p450
AMIR_RS16030	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMIR_RS16035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMIR_RS16065	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIR_RS16090	COG4585	Histidine kinase
AMIR_RS16095	COG2197	response regulator
AMIR_RS16125	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS16130	COG0667	Aldo Keto reductase
AMIR_RS16150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AMIR_RS16155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMIR_RS16380	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIR_RS16415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMIR_RS16430	COG0546	phosphoglycolate phosphatase activity
AMIR_RS16435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIR_RS16445	COG0604	alcohol dehydrogenase
AMIR_RS16445	COG3321	synthase
AMIR_RS16455	COG3321	synthase
AMIR_RS16455	COG0604	alcohol dehydrogenase
AMIR_RS16490	COG3693	PFAM glycoside hydrolase, family 10
AMIR_RS16490	COG3509	depolymerase
AMIR_RS16505	COG1609	Transcriptional regulator
AMIR_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS16555	COG2197	response regulator
AMIR_RS16560	COG4585	Histidine kinase
AMIR_RS16575	COG1073	alpha beta
AMIR_RS16590	COG0714	Associated with various cellular activities
AMIR_RS16655	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS16680	COG1609	Transcriptional regulator
AMIR_RS16690	COG1733	regulation of RNA biosynthetic process
AMIR_RS16705	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMIR_RS16705	COG1902	pentaerythritol trinitrate reductase activity
AMIR_RS16715	COG2267	carboxylic ester hydrolase activity
AMIR_RS16745	COG2261	transglycosylase associated protein
AMIR_RS16755	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMIR_RS16785	COG1064	alcohol dehydrogenase
AMIR_RS16800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AMIR_RS16805	COG0667	Aldo Keto reductase
AMIR_RS16820	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AMIR_RS16825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMIR_RS16855	COG0028	Belongs to the TPP enzyme family
AMIR_RS16875	COG0583	DNA-binding transcription factor activity
AMIR_RS16890	COG1233	COG1233 Phytoene dehydrogenase and related
AMIR_RS16915	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMIR_RS16940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMIR_RS16945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AMIR_RS16955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIR_RS16960	COG1607	acyl-coa hydrolase
AMIR_RS16980	COG0463	Glycosyl transferase, family 2
AMIR_RS17010	COG1435	thymidine kinase activity
AMIR_RS17025	COG2270	Major facilitator Superfamily
AMIR_RS17040	COG3706	GGDEF domain
AMIR_RS17055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AMIR_RS17085	COG0640	Transcriptional regulator
AMIR_RS17090	COG0798	PFAM Bile acid sodium symporter
AMIR_RS17095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMIR_RS17145	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS17165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIR_RS17170	COG1349	DNA-binding transcription factor activity
AMIR_RS17175	COG0494	nUDIX hydrolase
AMIR_RS17185	COG2176	DNA-directed DNA polymerase activity
AMIR_RS17185	COG5002	protein histidine kinase activity
AMIR_RS17230	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMIR_RS17250	COG1011	Hydrolase
AMIR_RS17260	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS17275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIR_RS17285	COG0747	negative chemotaxis
AMIR_RS17295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIR_RS17305	COG1609	Transcriptional regulator
AMIR_RS17320	COG1175	transmembrane transport
AMIR_RS17325	COG0395	ABC-type sugar transport system, permease component
AMIR_RS17330	COG4974	Belongs to the 'phage' integrase family
AMIR_RS17390	COG0667	Aldo Keto reductase
AMIR_RS17430	COG2755	lipolytic protein G-D-S-L family
AMIR_RS17465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMIR_RS17475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIR_RS17485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMIR_RS17495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIR_RS17510	COG1846	Transcriptional regulator
AMIR_RS17535	COG2130	NADP-dependent
AMIR_RS17545	COG1643	Atp-dependent helicase
AMIR_RS17565	COG1968	undecaprenyl-diphosphatase activity
AMIR_RS17570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS17575	COG0667	Aldo Keto reductase
AMIR_RS17610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMIR_RS17625	COG1414	Transcriptional regulator
AMIR_RS17635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMIR_RS17690	COG2814	Major facilitator Superfamily
AMIR_RS17745	COG1316	TRANSCRIPTIONal
AMIR_RS17750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS17770	COG1309	transcriptional regulator
AMIR_RS17785	COG4552	Acetyltransferase involved in intracellular survival and related
AMIR_RS17790	COG3507	Belongs to the glycosyl hydrolase 43 family
AMIR_RS17800	COG3903	Transcriptional regulator
AMIR_RS17800	COG3629	intracellular signal transduction
AMIR_RS17815	COG2197	response regulator
AMIR_RS17825	COG2124	cytochrome p450
AMIR_RS17850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS17855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMIR_RS17860	COG0604	alcohol dehydrogenase
AMIR_RS17860	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS17860	COG3321	synthase
AMIR_RS17885	COG0310	cobalt ion transport
AMIR_RS17915	COG2508	Transcriptional regulator
AMIR_RS17915	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AMIR_RS17920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMIR_RS17925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMIR_RS17940	COG2124	cytochrome p450
AMIR_RS18000	COG1136	(ABC) transporter
AMIR_RS18025	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS18060	COG0110	maltose O-acetyltransferase activity
AMIR_RS18090	COG2226	methyltransferase
AMIR_RS18160	COG1674	ftsk spoiiie
AMIR_RS18205	COG0667	Aldo Keto reductase
AMIR_RS18275	COG1132	(ABC) transporter
AMIR_RS18285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMIR_RS18285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMIR_RS18290	COG2192	nodulation
AMIR_RS18320	COG0367	asparagine synthase
AMIR_RS18365	COG2366	antibiotic biosynthetic process
AMIR_RS18375	COG1733	regulation of RNA biosynthetic process
AMIR_RS18415	COG1132	(ABC) transporter
AMIR_RS18465	COG3290	protein histidine kinase activity
AMIR_RS18485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS18495	COG1309	transcriptional regulator
AMIR_RS18515	COG3030	protein affecting phage T7 exclusion by the F plasmid
AMIR_RS18565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMIR_RS18595	COG3395	kinase activity
AMIR_RS18600	COG0235	Class ii aldolase
AMIR_RS18605	COG1349	DNA-binding transcription factor activity
AMIR_RS18620	COG0387	Pfam Sodium calcium exchanger
AMIR_RS18625	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIR_RS18625	COG2172	sigma factor antagonist activity
AMIR_RS18625	COG2208	phosphoserine phosphatase activity
AMIR_RS18630	COG3629	intracellular signal transduction
AMIR_RS18630	COG3903	Transcriptional regulator
AMIR_RS18645	COG0784	Response regulator, receiver
AMIR_RS18645	COG2205	protein histidine kinase activity
AMIR_RS18645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIR_RS18645	COG2198	Histidine kinase
AMIR_RS18655	COG2172	sigma factor antagonist activity
AMIR_RS18660	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIR_RS18665	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIR_RS18680	COG2072	flavoprotein involved in K transport
AMIR_RS18765	COG0789	Transcriptional regulator
AMIR_RS18790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIR_RS18840	COG3210	domain, Protein
AMIR_RS18895	COG4257	antibiotic catabolic process
AMIR_RS18930	COG3345	alpha-galactosidase
AMIR_RS18950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMIR_RS18955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMIR_RS18965	COG1959	2 iron, 2 sulfur cluster binding
AMIR_RS18970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIR_RS18970	COG1017	nitric oxide dioxygenase activity
AMIR_RS18995	COG0142	geranyltranstransferase activity
AMIR_RS19015	COG4106	trans-aconitate 2-methyltransferase activity
AMIR_RS19040	COG0667	Aldo Keto reductase
AMIR_RS19075	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMIR_RS19080	COG1021	2,3-dihydroxybenzoate-AMP ligase
AMIR_RS19090	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMIR_RS19095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMIR_RS19110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMIR_RS19135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIR_RS19145	COG0673	inositol 2-dehydrogenase activity
AMIR_RS19175	COG1309	transcriptional regulator
AMIR_RS19190	COG3537	Alpha-1,2-mannosidase
AMIR_RS19200	COG0596	Alpha beta hydrolase
AMIR_RS19225	COG2814	Major facilitator Superfamily
AMIR_RS19230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMIR_RS19285	COG2755	lipolytic protein G-D-S-L family
AMIR_RS19295	COG0745	RESPONSE REGULATOR receiver
AMIR_RS19310	COG4974	Belongs to the 'phage' integrase family
AMIR_RS19390	COG0300	oxidoreductase activity
AMIR_RS19390	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS19390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS19390	COG3321	synthase
AMIR_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS19395	COG2175	clavaminate synthase activity
AMIR_RS19425	COG0702	epimerase
AMIR_RS19430	COG0583	DNA-binding transcription factor activity
AMIR_RS19445	COG4221	oxidoreductase activity
AMIR_RS19445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS19445	COG3321	synthase
AMIR_RS19445	COG0604	alcohol dehydrogenase
AMIR_RS19480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS19495	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMIR_RS19500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS19545	COG2192	nodulation
AMIR_RS19555	COG3940	Belongs to the glycosyl hydrolase 43 family
AMIR_RS19580	COG0667	Aldo Keto reductase
AMIR_RS19590	COG2192	nodulation
AMIR_RS19615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMIR_RS19660	COG2197	response regulator
AMIR_RS19670	COG1309	transcriptional regulator
AMIR_RS19720	COG3509	depolymerase
AMIR_RS19745	COG1064	alcohol dehydrogenase
AMIR_RS19795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMIR_RS19800	COG1309	transcriptional regulator
AMIR_RS19805	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS19820	COG3226	Transcriptional regulator
AMIR_RS19825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIR_RS19840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIR_RS19855	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS19870	COG0435	Glutathione S-transferase
AMIR_RS19900	COG0596	Alpha beta hydrolase
AMIR_RS19905	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMIR_RS19930	COG2197	response regulator
AMIR_RS19970	COG0673	inositol 2-dehydrogenase activity
AMIR_RS19990	COG4335	DNA alkylation repair
AMIR_RS19995	COG0596	Alpha beta hydrolase
AMIR_RS20000	COG0745	RESPONSE REGULATOR receiver
AMIR_RS20005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMIR_RS20035	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIR_RS20070	COG0515	serine threonine protein kinase
AMIR_RS20095	COG0492	ferredoxin-NADP+ reductase activity
AMIR_RS20110	COG0475	glutathione-regulated potassium exporter activity
AMIR_RS20160	COG1132	(ABC) transporter
AMIR_RS20180	COG1136	(ABC) transporter
AMIR_RS20190	COG2197	response regulator
AMIR_RS20195	COG3851	Histidine kinase
AMIR_RS20245	COG3284	Transcriptional regulator
AMIR_RS20260	COG1309	transcriptional regulator
AMIR_RS20270	COG5002	protein histidine kinase activity
AMIR_RS20275	COG0745	RESPONSE REGULATOR receiver
AMIR_RS20285	COG0577	efflux transmembrane transporter activity
AMIR_RS20285	COG1136	(ABC) transporter
AMIR_RS20290	COG0577	efflux transmembrane transporter activity
AMIR_RS20315	COG2345	Transcriptional regulator
AMIR_RS20350	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS20360	COG2814	Major facilitator Superfamily
AMIR_RS20390	COG0596	Alpha beta hydrolase
AMIR_RS20415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMIR_RS20425	COG0300	oxidoreductase activity
AMIR_RS20430	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AMIR_RS20440	COG2124	cytochrome p450
AMIR_RS20450	COG2207	Transcriptional regulator
AMIR_RS20500	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS20505	COG1024	Enoyl-CoA hydratase
AMIR_RS20520	COG1917	Cupin 2, conserved barrel domain protein
AMIR_RS20520	COG4977	sequence-specific DNA binding
AMIR_RS20560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMIR_RS20570	COG1609	Transcriptional regulator
AMIR_RS20580	COG4948	Mandelate Racemase Muconate Lactonizing
AMIR_RS20605	COG2205	protein histidine kinase activity
AMIR_RS20610	COG0745	RESPONSE REGULATOR receiver
AMIR_RS20655	COG2267	carboxylic ester hydrolase activity
AMIR_RS20710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMIR_RS20720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMIR_RS20740	COG1414	Transcriptional regulator
AMIR_RS20745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMIR_RS20750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMIR_RS20785	COG3340	Belongs to the peptidase S51 family
AMIR_RS20810	COG3321	synthase
AMIR_RS20810	COG0604	alcohol dehydrogenase
AMIR_RS20835	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AMIR_RS20845	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMIR_RS20885	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMIR_RS20890	COG1404	Belongs to the peptidase S8 family
AMIR_RS20895	COG1404	Belongs to the peptidase S8 family
AMIR_RS20900	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AMIR_RS20900	COG4932	domain protein
AMIR_RS20900	COG3266	domain, Protein
AMIR_RS20930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIR_RS20935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMIR_RS20945	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AMIR_RS20955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIR_RS20955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIR_RS20965	COG0697	spore germination
AMIR_RS20970	COG0644	oxidoreductase
AMIR_RS20980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS20990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS21040	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMIR_RS21055	COG0659	secondary active sulfate transmembrane transporter activity
AMIR_RS21080	COG3467	pyridoxamine 5'-phosphate
AMIR_RS21085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMIR_RS21090	COG2124	cytochrome p450
AMIR_RS21100	COG0726	polysaccharide deacetylase
AMIR_RS21105	COG0439	Biotin carboxylase
AMIR_RS21110	COG0395	ABC-type sugar transport system, permease component
AMIR_RS21115	COG1175	transmembrane transport
AMIR_RS21120	COG2182	Extracellular solute-binding protein
AMIR_RS21130	COG0667	Aldo Keto reductase
AMIR_RS21150	COG0300	oxidoreductase activity
AMIR_RS21200	COG0110	maltose O-acetyltransferase activity
AMIR_RS21215	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMIR_RS21230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMIR_RS21235	COG2197	response regulator
AMIR_RS21240	COG3850	Histidine kinase
AMIR_RS21305	COG1902	pentaerythritol trinitrate reductase activity
AMIR_RS21335	COG0640	Transcriptional regulator
AMIR_RS21350	COG0640	Transcriptional regulator
AMIR_RS21355	COG0672	)-iron permease
AMIR_RS21365	COG2837	iron assimilation
AMIR_RS21380	COG0596	Alpha beta hydrolase
AMIR_RS21385	COG1120	ATPase activity
AMIR_RS21390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS21395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS21420	COG1982	Orn Lys Arg decarboxylase major
AMIR_RS21455	COG0277	FAD linked oxidase domain protein
AMIR_RS21475	COG0583	DNA-binding transcription factor activity
AMIR_RS21480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS21485	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS21525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMIR_RS21530	COG4172	Belongs to the ABC transporter superfamily
AMIR_RS21575	COG0784	Response regulator, receiver
AMIR_RS21585	COG1522	sequence-specific DNA binding
AMIR_RS21595	COG0861	Integral membrane protein TerC family
AMIR_RS21600	COG1309	transcriptional regulator
AMIR_RS21610	COG2807	transmembrane transport
AMIR_RS21620	COG0475	glutathione-regulated potassium exporter activity
AMIR_RS21635	COG2814	Major facilitator Superfamily
AMIR_RS21675	COG2986	histidine ammonia-lyase
AMIR_RS21695	COG3321	synthase
AMIR_RS21695	COG0604	alcohol dehydrogenase
AMIR_RS21745	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS21760	COG0183	Belongs to the thiolase family
AMIR_RS21765	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIR_RS21765	COG1024	Enoyl-CoA hydratase
AMIR_RS21785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMIR_RS21785	COG2010	Cytochrome c
AMIR_RS21790	COG2080	2 iron, 2 sulfur cluster binding
AMIR_RS21800	COG0142	geranyltranstransferase activity
AMIR_RS21805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMIR_RS21810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMIR_RS21820	COG2175	clavaminate synthase activity
AMIR_RS21835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMIR_RS21865	COG2340	Cysteine-rich secretory protein family
AMIR_RS21880	COG1309	transcriptional regulator
AMIR_RS21895	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS21900	COG1309	transcriptional regulator
AMIR_RS21905	COG0789	Transcriptional regulator
AMIR_RS21925	COG3831	ATPase activity
AMIR_RS21940	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS21980	COG0254	rRNA binding
AMIR_RS21990	COG0753	catalase activity
AMIR_RS21995	COG0519	Catalyzes the synthesis of GMP from XMP
AMIR_RS21995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMIR_RS22000	COG2258	MOSC domain
AMIR_RS22020	COG0604	alcohol dehydrogenase
AMIR_RS22030	COG0604	alcohol dehydrogenase
AMIR_RS22070	COG2197	response regulator
AMIR_RS22075	COG4585	Histidine kinase
AMIR_RS22095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMIR_RS22100	COG1121	(ABC) transporter
AMIR_RS22105	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMIR_RS22110	COG0604	alcohol dehydrogenase
AMIR_RS22110	COG3321	synthase
AMIR_RS22115	COG0604	alcohol dehydrogenase
AMIR_RS22115	COG0604	alcohol dehydrogenase
AMIR_RS22115	COG3321	synthase
AMIR_RS22115	COG3321	synthase
AMIR_RS22120	COG0604	alcohol dehydrogenase
AMIR_RS22120	COG3321	synthase
AMIR_RS22135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMIR_RS22165	COG3629	intracellular signal transduction
AMIR_RS22190	COG0730	response to heat
AMIR_RS22205	COG4221	oxidoreductase activity
AMIR_RS22250	COG1022	Amp-dependent synthetase and ligase
AMIR_RS22265	COG1309	transcriptional regulator
AMIR_RS22270	COG0778	Nitroreductase
AMIR_RS22295	COG1063	alcohol dehydrogenase
AMIR_RS22325	COG1509	lysine 2,3-aminomutase activity
AMIR_RS22335	COG0644	oxidoreductase
AMIR_RS22340	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AMIR_RS22345	COG2808	Putative FMN-binding domain
AMIR_RS22395	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AMIR_RS22400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMIR_RS22405	COG0165	Argininosuccinate lyase
AMIR_RS22440	COG3973	AAA domain
AMIR_RS22445	COG2409	Drug exporters of the RND superfamily
AMIR_RS22455	COG2197	response regulator
AMIR_RS22465	COG2205	protein histidine kinase activity
AMIR_RS22470	COG0745	RESPONSE REGULATOR receiver
AMIR_RS22575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIR_RS22750	COG0546	phosphoglycolate phosphatase activity
AMIR_RS22820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS22825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS22865	COG3903	Transcriptional regulator
AMIR_RS22865	COG3629	intracellular signal transduction
AMIR_RS22875	COG2124	cytochrome p450
AMIR_RS22895	COG0300	oxidoreductase activity
AMIR_RS22905	COG0604	alcohol dehydrogenase
AMIR_RS22905	COG3321	synthase
AMIR_RS22915	COG2272	Belongs to the type-B carboxylesterase lipase family
AMIR_RS22925	COG1609	Transcriptional regulator
AMIR_RS22935	COG1175	transmembrane transport
AMIR_RS22940	COG0395	ABC-type sugar transport system, permease component
AMIR_RS22945	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIR_RS22980	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS22995	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS23045	COG0583	DNA-binding transcription factor activity
AMIR_RS23050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMIR_RS23055	COG3250	beta-galactosidase activity
AMIR_RS23065	COG2909	trisaccharide binding
AMIR_RS23070	COG4221	oxidoreductase activity
AMIR_RS23070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMIR_RS23070	COG3321	synthase
AMIR_RS23070	COG0604	alcohol dehydrogenase
AMIR_RS23140	COG1022	Amp-dependent synthetase and ligase
AMIR_RS23150	COG0657	acetylesterase activity
AMIR_RS23155	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIR_RS23155	COG0022	dehydrogenase e1 component
AMIR_RS23160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMIR_RS23180	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS23210	COG2755	lipolytic protein G-D-S-L family
AMIR_RS23220	COG2201	protein-glutamate methylesterase activity
AMIR_RS23245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS23260	COG2755	lipolytic protein G-D-S-L family
AMIR_RS23290	COG1309	transcriptional regulator
AMIR_RS23295	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS23300	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS23360	COG3321	synthase
AMIR_RS23360	COG0604	alcohol dehydrogenase
AMIR_RS23380	COG0702	epimerase
AMIR_RS23395	COG1733	regulation of RNA biosynthetic process
AMIR_RS23435	COG0006	proline dipeptidase activity
AMIR_RS23450	COG0444	Belongs to the ABC transporter superfamily
AMIR_RS23465	COG0747	negative chemotaxis
AMIR_RS23470	COG1802	Transcriptional regulator
AMIR_RS23480	COG3938	Belongs to the proline racemase family
AMIR_RS23485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMIR_RS23510	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMIR_RS23515	COG1609	Transcriptional regulator
AMIR_RS23525	COG0402	S-adenosylhomocysteine deaminase activity
AMIR_RS23585	COG1131	(ABC) transporter
AMIR_RS23595	COG1595	DNA-templated transcription, initiation
AMIR_RS23670	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMIR_RS23710	COG1121	(ABC) transporter
AMIR_RS23715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMIR_RS23725	COG0523	cobalamin synthesis protein
AMIR_RS23775	COG1120	ATPase activity
AMIR_RS23780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS23815	COG0583	DNA-binding transcription factor activity
AMIR_RS23820	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS23830	COG1309	transcriptional regulator
AMIR_RS23835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMIR_RS23840	COG2391	methyltransferase activity
AMIR_RS23865	COG0477	Major facilitator Superfamily
AMIR_RS23870	COG1309	transcriptional regulator
AMIR_RS23930	COG2018	Roadblock/LC7 domain
AMIR_RS23945	COG0673	inositol 2-dehydrogenase activity
AMIR_RS23960	COG1929	Belongs to the glycerate kinase type-1 family
AMIR_RS23980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMIR_RS24030	COG2124	cytochrome p450
AMIR_RS24040	COG1216	Glycosyl transferase, family 2
AMIR_RS24050	COG0702	epimerase
AMIR_RS24065	COG1819	glycosyl
AMIR_RS24080	COG1819	glycosyl
AMIR_RS24090	COG0515	serine threonine protein kinase
AMIR_RS24105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMIR_RS24110	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS24130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIR_RS24130	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS24135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMIR_RS24140	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS24150	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS24155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMIR_RS24160	COG1132	(ABC) transporter
AMIR_RS24165	COG1309	transcriptional regulator
AMIR_RS24180	COG3386	PFAM SMP-30 Gluconolaconase
AMIR_RS24185	COG2072	flavoprotein involved in K transport
AMIR_RS24205	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIR_RS24235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMIR_RS24240	COG0494	nUDIX hydrolase
AMIR_RS24250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIR_RS24265	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AMIR_RS24275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIR_RS24285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIR_RS24295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIR_RS24305	COG0583	DNA-binding transcription factor activity
AMIR_RS24320	COG1902	pentaerythritol trinitrate reductase activity
AMIR_RS24355	COG1802	Transcriptional regulator
AMIR_RS24365	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS24370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS24390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS24400	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS24425	COG2022	thiamine diphosphate biosynthetic process
AMIR_RS24440	COG2208	phosphoserine phosphatase activity
AMIR_RS24440	COG2770	Histidine kinase
AMIR_RS24450	COG2365	Tyrosine phosphatase family
AMIR_RS24460	COG2755	lipolytic protein G-D-S-L family
AMIR_RS24465	COG3835	regulator
AMIR_RS24495	COG1929	Belongs to the glycerate kinase type-1 family
AMIR_RS24505	COG2205	protein histidine kinase activity
AMIR_RS24510	COG0745	RESPONSE REGULATOR receiver
AMIR_RS24525	COG0477	Major facilitator Superfamily
AMIR_RS24535	COG0583	DNA-binding transcription factor activity
AMIR_RS24550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMIR_RS24570	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AMIR_RS24615	COG0463	Glycosyl transferase, family 2
AMIR_RS24625	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS24650	COG1472	Belongs to the glycosyl hydrolase 3 family
AMIR_RS24670	COG3693	PFAM glycoside hydrolase, family 10
AMIR_RS24685	COG0500	methyltransferase
AMIR_RS24700	COG2409	Drug exporters of the RND superfamily
AMIR_RS24720	COG1253	flavin adenine dinucleotide binding
AMIR_RS24770	COG0009	L-threonylcarbamoyladenylate synthase
AMIR_RS24795	COG2197	response regulator
AMIR_RS24815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIR_RS24820	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIR_RS24835	COG1522	sequence-specific DNA binding
AMIR_RS24840	COG2340	Cysteine-rich secretory protein family
AMIR_RS24845	COG2205	protein histidine kinase activity
AMIR_RS24895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMIR_RS24900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMIR_RS24905	COG0142	geranyltranstransferase activity
AMIR_RS24915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMIR_RS24935	COG0463	Glycosyl transferase, family 2
AMIR_RS24940	COG1064	alcohol dehydrogenase
AMIR_RS24945	COG1309	transcriptional regulator
AMIR_RS24955	COG2855	membrane
AMIR_RS24970	COG4251	negative regulation of phosphorylation
AMIR_RS24975	COG0784	Response regulator, receiver
AMIR_RS25010	COG3973	AAA domain
AMIR_RS25025	COG1309	transcriptional regulator
AMIR_RS25030	COG0300	oxidoreductase activity
AMIR_RS25040	COG0823	Involved in the tonB-independent uptake of proteins
AMIR_RS25055	COG3973	AAA domain
AMIR_RS25060	COG1120	ATPase activity
AMIR_RS25065	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS25070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMIR_RS25080	COG1063	alcohol dehydrogenase
AMIR_RS25085	COG0477	Major facilitator Superfamily
AMIR_RS25090	COG0246	Mannitol dehydrogenase
AMIR_RS25120	COG4607	ABC-type enterochelin transport system periplasmic component
AMIR_RS25125	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AMIR_RS25130	COG1132	(ABC) transporter
AMIR_RS25140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIR_RS25170	COG0583	DNA-binding transcription factor activity
AMIR_RS25190	COG1414	Transcriptional regulator
AMIR_RS25195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMIR_RS25200	COG2267	carboxylic ester hydrolase activity
AMIR_RS25205	COG3485	protocatechuate 3,4-dioxygenase
AMIR_RS25210	COG3485	protocatechuate 3,4-dioxygenase
AMIR_RS25215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AMIR_RS25220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMIR_RS25235	COG2770	Histidine kinase
AMIR_RS25235	COG2208	phosphoserine phosphatase activity
AMIR_RS25240	COG0784	Response regulator, receiver
AMIR_RS25240	COG5002	protein histidine kinase activity
AMIR_RS25255	COG0248	Ppx GppA phosphatase
AMIR_RS25275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS25285	COG1609	Transcriptional regulator
AMIR_RS25290	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMIR_RS25295	COG0300	oxidoreductase activity
AMIR_RS25300	COG1309	transcriptional regulator
AMIR_RS25355	COG1609	Transcriptional regulator
AMIR_RS25370	COG0739	heme binding
AMIR_RS25375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMIR_RS25380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIR_RS25390	COG0596	Alpha beta hydrolase
AMIR_RS25405	COG0583	DNA-binding transcription factor activity
AMIR_RS25415	COG1349	DNA-binding transcription factor activity
AMIR_RS25420	COG4821	SIS domain
AMIR_RS25425	COG1132	(ABC) transporter
AMIR_RS25430	COG1024	Enoyl-CoA hydratase
AMIR_RS25440	COG0488	(ABC) transporter
AMIR_RS25445	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS25480	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMIR_RS25510	COG3706	GGDEF domain
AMIR_RS25525	COG2151	metal-sulfur cluster biosynthetic enzyme
AMIR_RS25530	COG0822	iron-sulfur transferase activity
AMIR_RS25540	COG0396	ATPase activity
AMIR_RS25580	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMIR_RS25595	COG1131	(ABC) transporter
AMIR_RS25635	COG1510	regulation of RNA biosynthetic process
AMIR_RS25645	COG2018	Roadblock/LC7 domain
AMIR_RS25650	COG5002	protein histidine kinase activity
AMIR_RS25660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMIR_RS25715	COG0109	protoheme IX farnesyltransferase activity
AMIR_RS25725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMIR_RS25730	COG0166	Belongs to the GPI family
AMIR_RS25745	COG0363	glucosamine-6-phosphate deaminase activity
AMIR_RS25750	COG4585	Histidine kinase
AMIR_RS25770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMIR_RS25775	COG0149	triose-phosphate isomerase activity
AMIR_RS25780	COG0126	phosphoglycerate kinase activity
AMIR_RS25785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMIR_RS25800	COG1481	regulation of sporulation
AMIR_RS25810	COG1660	Displays ATPase and GTPase activities
AMIR_RS25815	COG0322	excinuclease ABC activity
AMIR_RS25860	COG2234	aminopeptidase activity
AMIR_RS25870	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMIR_RS25875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIR_RS25875	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMIR_RS25905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMIR_RS25910	COG0242	peptide deformylase activity
AMIR_RS25940	COG0405	Gamma-glutamyltransferase
AMIR_RS25955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMIR_RS25965	COG1758	RNA polymerase activity
AMIR_RS25970	COG0194	GDP metabolic process
AMIR_RS25980	COG0284	orotidine-5'-phosphate decarboxylase activity
AMIR_RS25990	COG0505	Belongs to the CarA family
AMIR_RS26005	COG0540	Belongs to the ATCase OTCase family
AMIR_RS26010	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AMIR_RS26020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMIR_RS26025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMIR_RS26030	COG0006	proline dipeptidase activity
AMIR_RS26040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMIR_RS26045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMIR_RS26050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMIR_RS26055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMIR_RS26065	COG2190	(PTS) system
AMIR_RS26070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMIR_RS26075	COG2188	Transcriptional regulator
AMIR_RS26080	COG1263	PTS System
AMIR_RS26085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMIR_RS26090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMIR_RS26100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMIR_RS26105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMIR_RS26145	COG4581	dead DEAH box helicase
AMIR_RS26155	COG1388	LysM domain
AMIR_RS26165	COG3279	Response regulator of the LytR AlgR family
AMIR_RS26175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMIR_RS26180	COG3275	phosphorelay sensor kinase activity
AMIR_RS26200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMIR_RS26225	COG1733	regulation of RNA biosynthetic process
AMIR_RS26245	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AMIR_RS26310	COG0395	ABC-type sugar transport system, permease component
AMIR_RS26330	COG1024	Enoyl-CoA hydratase
AMIR_RS26355	COG2258	MOSC domain
AMIR_RS26360	COG0667	Aldo Keto reductase
AMIR_RS26370	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS26370	COG2030	dehydratase
AMIR_RS26385	COG3903	Transcriptional regulator
AMIR_RS26385	COG3629	intracellular signal transduction
AMIR_RS26390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMIR_RS26390	COG2755	lipolytic protein G-D-S-L family
AMIR_RS26400	COG1132	(ABC) transporter
AMIR_RS26425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMIR_RS26430	COG0564	pseudouridine synthase activity
AMIR_RS26480	COG1609	Transcriptional regulator
AMIR_RS26525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMIR_RS26525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMIR_RS26545	COG1716	ATPase activity
AMIR_RS26595	COG0667	Aldo Keto reductase
AMIR_RS26640	COG2197	response regulator
AMIR_RS26645	COG2197	response regulator
AMIR_RS26725	COG1222	aaa ATPase
AMIR_RS26770	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIR_RS26775	COG1366	Belongs to the anti-sigma-factor antagonist family
AMIR_RS26795	COG4977	sequence-specific DNA binding
AMIR_RS26845	COG2018	Roadblock/LC7 domain
AMIR_RS26855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMIR_RS26865	COG1116	anion transmembrane transporter activity
AMIR_RS26865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMIR_RS26870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIR_RS26875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMIR_RS26885	COG1187	pseudouridine synthase activity
AMIR_RS26890	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMIR_RS26895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMIR_RS26910	COG0640	Transcriptional regulator
AMIR_RS26930	COG0494	nUDIX hydrolase
AMIR_RS26935	COG0504	CTP synthase activity
AMIR_RS26960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMIR_RS26970	COG0647	UMP catabolic process
AMIR_RS26995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMIR_RS27010	COG2094	Belongs to the DNA glycosylase MPG family
AMIR_RS27015	COG0165	Argininosuccinate lyase
AMIR_RS27020	COG0137	argininosuccinate synthase activity
AMIR_RS27025	COG1438	arginine binding
AMIR_RS27040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMIR_RS27045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMIR_RS27050	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMIR_RS27055	COG0604	alcohol dehydrogenase
AMIR_RS27065	COG1476	TRANSCRIPTIONal
AMIR_RS27085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMIR_RS27085	COG0072	phenylalanine-tRNA ligase activity
AMIR_RS27090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMIR_RS27095	COG0326	Molecular chaperone. Has ATPase activity
AMIR_RS27105	COG0745	RESPONSE REGULATOR receiver
AMIR_RS27110	COG0642	Histidine kinase
AMIR_RS27115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMIR_RS27120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMIR_RS27125	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMIR_RS27130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMIR_RS27145	COG3903	Transcriptional regulator
AMIR_RS27145	COG3629	intracellular signal transduction
AMIR_RS27170	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AMIR_RS27175	COG2610	gluconate transmembrane transporter activity
AMIR_RS27195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMIR_RS27215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIR_RS27220	COG0640	Transcriptional regulator
AMIR_RS27285	COG5650	phosphatidylinositol metabolic process
AMIR_RS27315	COG1506	peptidase
AMIR_RS27315	COG0823	Involved in the tonB-independent uptake of proteins
AMIR_RS27315	COG4946	Tricorn protease homolog
AMIR_RS27325	COG1131	(ABC) transporter
AMIR_RS27355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMIR_RS27355	COG0237	dephospho-CoA kinase activity
AMIR_RS27365	COG0539	negative regulation of cytoplasmic translation
AMIR_RS27385	COG1511	domain protein
AMIR_RS27390	COG1309	transcriptional regulator
AMIR_RS27405	COG0673	inositol 2-dehydrogenase activity
AMIR_RS27420	COG2050	protein possibly involved in aromatic compounds catabolism
AMIR_RS27430	COG0410	ABC transporter
AMIR_RS27445	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS27475	COG1832	CoA-binding protein
AMIR_RS27480	COG0251	oxidation-reduction process
AMIR_RS27495	COG1357	PFAM Pentapeptide repeats (8 copies)
AMIR_RS27500	COG0514	ATP-dependent DNA helicase (RecQ)
AMIR_RS27680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMIR_RS27680	COG0758	DNA mediated transformation
AMIR_RS27685	COG1040	competence protein
AMIR_RS27995	COG1937	Protein conserved in bacteria
AMIR_RS28015	COG1595	DNA-templated transcription, initiation
AMIR_RS28020	COG1408	metallophosphoesterase
AMIR_RS28030	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AMIR_RS28045	COG0778	Nitroreductase
AMIR_RS28050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMIR_RS28055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMIR_RS28065	COG1566	PFAM secretion protein HlyD family protein
AMIR_RS28080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMIR_RS28085	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS28095	COG0183	Belongs to the thiolase family
AMIR_RS28100	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMIR_RS28100	COG1024	Enoyl-CoA hydratase
AMIR_RS28125	COG1136	(ABC) transporter
AMIR_RS28125	COG0577	efflux transmembrane transporter activity
AMIR_RS28130	COG0577	efflux transmembrane transporter activity
AMIR_RS28130	COG1136	(ABC) transporter
AMIR_RS28135	COG1672	PFAM Archaeal ATPase
AMIR_RS28135	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMIR_RS28140	COG3629	intracellular signal transduction
AMIR_RS28140	COG3903	Transcriptional regulator
AMIR_RS28170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AMIR_RS28185	COG1946	Acyl-CoA thioesterase
AMIR_RS28220	COG0070	glutamate synthase
AMIR_RS28220	COG0069	glutamate synthase activity
AMIR_RS28220	COG0067	glutamate synthase
AMIR_RS28225	COG1301	dicarboxylic acid transport
AMIR_RS28235	COG2205	protein histidine kinase activity
AMIR_RS28245	COG0745	RESPONSE REGULATOR receiver
AMIR_RS28250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMIR_RS28255	COG0159	tryptophan synthase activity
AMIR_RS28260	COG0133	tryptophan synthase activity
AMIR_RS28265	COG0134	indole-3-glycerol-phosphate synthase activity
AMIR_RS28275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMIR_RS28285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMIR_RS28295	COG0107	imidazoleglycerol-phosphate synthase activity
AMIR_RS28300	COG3654	unkown
AMIR_RS28315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMIR_RS28320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMIR_RS28330	COG3958	Transketolase
AMIR_RS28335	COG3959	Transketolase, thiamine diphosphate binding domain
AMIR_RS28345	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AMIR_RS28350	COG0131	Imidazoleglycerol-phosphate dehydratase
AMIR_RS28355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMIR_RS28360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMIR_RS28370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMIR_RS28395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMIR_RS28415	COG2814	Major facilitator Superfamily
AMIR_RS28440	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMIR_RS28455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMIR_RS28470	COG2814	Major facilitator Superfamily
AMIR_RS28480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMIR_RS28490	COG3263	regulation of cellular component size
AMIR_RS28505	COG1872	DUF167
AMIR_RS28510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMIR_RS28530	COG1799	cell septum assembly
AMIR_RS28545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMIR_RS28550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMIR_RS28555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMIR_RS28560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMIR_RS28585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMIR_RS28590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMIR_RS28605	COG0768	penicillin binding
AMIR_RS28615	COG0275	rRNA processing
AMIR_RS28620	COG2001	Belongs to the MraZ family
AMIR_RS28625	COG0714	Associated with various cellular activities
AMIR_RS28655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMIR_RS28660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMIR_RS28670	COG0174	glutamine synthetase
AMIR_RS28685	COG1192	Involved in chromosome partitioning
AMIR_RS28690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMIR_RS28695	COG0167	dihydroorotate dehydrogenase activity
AMIR_RS28705	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS28710	COG2233	PERMEase
AMIR_RS28720	COG1842	Phage shock protein A
AMIR_RS28725	COG1396	sequence-specific DNA binding
AMIR_RS28730	COG1546	Belongs to the CinA family
AMIR_RS28730	COG1058	Belongs to the CinA family
AMIR_RS28740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMIR_RS28745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMIR_RS28770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AMIR_RS28775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMIR_RS28785	COG0515	serine threonine protein kinase
AMIR_RS28795	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AMIR_RS28810	COG1309	transcriptional regulator
AMIR_RS28820	COG0667	Aldo Keto reductase
AMIR_RS28825	COG3214	Protein conserved in bacteria
AMIR_RS28845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMIR_RS28855	COG1185	polyribonucleotide nucleotidyltransferase activity
AMIR_RS28860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMIR_RS28880	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMIR_RS28895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AMIR_RS28920	COG0779	Required for maturation of 30S ribosomal subunits
AMIR_RS28945	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS28970	COG0442	prolyl-tRNA aminoacylation
AMIR_RS28980	COG3022	response to hydroperoxide
AMIR_RS28985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMIR_RS29000	COG0513	Belongs to the DEAD box helicase family
AMIR_RS29005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMIR_RS29005	COG1648	precorrin-2 dehydrogenase activity
AMIR_RS29055	COG0156	8-amino-7-oxononanoate synthase activity
AMIR_RS29070	COG1280	lysine exporter protein (LysE YggA)
AMIR_RS29085	COG0501	Belongs to the peptidase M48B family
AMIR_RS29095	COG0110	maltose O-acetyltransferase activity
AMIR_RS29100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMIR_RS29110	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMIR_RS29115	COG0726	polysaccharide deacetylase
AMIR_RS29120	COG1881	PFAM PEBP family protein
AMIR_RS29130	COG2807	transmembrane transport
AMIR_RS29135	COG2186	Transcriptional regulator
AMIR_RS29150	COG1492	cobalamin metabolic process
AMIR_RS29175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMIR_RS29180	COG0750	zinc metalloprotease
AMIR_RS29185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMIR_RS29200	COG2197	response regulator
AMIR_RS29205	COG4585	Histidine kinase
AMIR_RS29210	COG1177	transmembrane transport
AMIR_RS29215	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMIR_RS29225	COG3842	ATPase activity
AMIR_RS29235	COG0515	serine threonine protein kinase
AMIR_RS29235	COG2815	serine threonine protein kinase
AMIR_RS29245	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMIR_RS29255	COG0667	Aldo Keto reductase
AMIR_RS29275	COG0233	cytoplasmic translational termination
AMIR_RS29280	COG0528	UMP kinase activity
AMIR_RS29285	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMIR_RS29290	COG0052	Belongs to the universal ribosomal protein uS2 family
AMIR_RS29300	COG1191	sigma factor activity
AMIR_RS29320	COG0792	nuclease activity
AMIR_RS29330	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMIR_RS29335	COG0681	Belongs to the peptidase S26 family
AMIR_RS29340	COG0681	Belongs to the peptidase S26 family
AMIR_RS29345	COG0335	large ribosomal subunit rRNA binding
AMIR_RS29350	COG0336	Belongs to the RNA methyltransferase TrmD family
AMIR_RS29365	COG0228	four-way junction DNA binding
AMIR_RS29370	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AMIR_RS29395	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMIR_RS29415	COG4266	Belongs to the allantoicase family
AMIR_RS29420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMIR_RS29445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMIR_RS29450	COG1414	Transcriptional regulator
AMIR_RS29465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMIR_RS29475	COG0454	-acetyltransferase
AMIR_RS29475	COG0456	acetyltransferase
AMIR_RS29510	COG1254	Belongs to the acylphosphatase family
AMIR_RS29530	COG1252	NADH dehydrogenase
AMIR_RS29545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMIR_RS29555	COG0571	ribonuclease III activity
AMIR_RS29560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMIR_RS29575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMIR_RS29580	COG0742	ribosomal rna small subunit methyltransferase
AMIR_RS29620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMIR_RS29625	COG1461	Dihydroxyacetone kinase
AMIR_RS29630	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMIR_RS29645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMIR_RS29650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMIR_RS29675	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMIR_RS29690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIR_RS29715	COG0626	cystathionine gamma-synthase activity
AMIR_RS29720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMIR_RS29730	COG1920	GTP binding
AMIR_RS29745	COG0406	alpha-ribazole phosphatase activity
AMIR_RS29745	COG0494	nUDIX hydrolase
AMIR_RS29755	COG0066	3-isopropylmalate dehydratase activity
AMIR_RS29760	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMIR_RS29790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMIR_RS29800	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMIR_RS29810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIR_RS29815	COG0473	3-isopropylmalate dehydrogenase activity
AMIR_RS29820	COG1404	Belongs to the peptidase S8 family
AMIR_RS29835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMIR_RS29840	COG0440	acetolactate synthase activity
AMIR_RS29860	COG0129	dihydroxy-acid dehydratase activity
AMIR_RS29910	COG0154	amidase activity
AMIR_RS29915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMIR_RS29930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMIR_RS29945	COG2855	membrane
AMIR_RS29965	COG0482	sulfurtransferase activity
AMIR_RS29990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AMIR_RS30000	COG1307	EDD domain protein, DegV family
AMIR_RS30015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMIR_RS30040	COG0110	maltose O-acetyltransferase activity
AMIR_RS30055	COG2226	methyltransferase
AMIR_RS30065	COG1119	ATPase activity
AMIR_RS30090	COG0058	SHG alpha-glucan phosphorylase activity
AMIR_RS30095	COG0366	Alpha amylase catalytic
AMIR_RS30100	COG0366	Alpha amylase catalytic
AMIR_RS30110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMIR_RS30115	COG2321	neutral zinc metallopeptidase
AMIR_RS30145	COG1846	Transcriptional regulator
AMIR_RS30155	COG2409	Drug exporters of the RND superfamily
AMIR_RS30160	COG1131	(ABC) transporter
AMIR_RS30185	COG1609	Transcriptional regulator
AMIR_RS30200	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS30205	COG1879	ABC-type sugar transport system periplasmic component
AMIR_RS30215	COG0596	Alpha beta hydrolase
AMIR_RS30255	COG0183	Belongs to the thiolase family
AMIR_RS30260	COG0346	lactoylglutathione lyase activity
AMIR_RS30305	COG2376	Dihydroxyacetone kinase
AMIR_RS30355	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AMIR_RS30370	COG1024	Enoyl-CoA hydratase
AMIR_RS30375	COG1335	isochorismatase
AMIR_RS30410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMIR_RS30415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMIR_RS30420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMIR_RS30425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMIR_RS30430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMIR_RS30435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMIR_RS30440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMIR_RS30445	COG0356	it plays a direct role in the translocation of protons across the membrane
AMIR_RS30460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMIR_RS30470	COG2890	protein-(glutamine-N5) methyltransferase activity
AMIR_RS30490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMIR_RS30495	COG0254	rRNA binding
AMIR_RS30505	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMIR_RS30510	COG0083	homoserine kinase activity
AMIR_RS30515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMIR_RS30520	COG0460	homoserine dehydrogenase
AMIR_RS30525	COG0019	diaminopimelate decarboxylase activity
AMIR_RS30530	COG0018	arginyl-trna synthetase
AMIR_RS30545	COG3537	Alpha-1,2-mannosidase
AMIR_RS30575	COG3629	intracellular signal transduction
AMIR_RS30575	COG3903	Transcriptional regulator
AMIR_RS30580	COG0596	Alpha beta hydrolase
AMIR_RS30620	COG1162	GTPase activity
AMIR_RS30630	COG0667	Aldo Keto reductase
AMIR_RS30635	COG1609	Transcriptional regulator
AMIR_RS30665	COG0444	Belongs to the ABC transporter superfamily
AMIR_RS30670	COG0601	transmembrane transport
AMIR_RS30675	COG4166	transmembrane transport
AMIR_RS30690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS30700	COG2890	protein-(glutamine-N5) methyltransferase activity
AMIR_RS30705	COG4941	Belongs to the sigma-70 factor family
AMIR_RS30710	COG3795	YCII-related domain
AMIR_RS30740	COG0640	Transcriptional regulator
AMIR_RS30750	COG1940	carbohydrate kinase activity
AMIR_RS30765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMIR_RS30770	COG0745	RESPONSE REGULATOR receiver
AMIR_RS30775	COG2205	protein histidine kinase activity
AMIR_RS30795	COG1404	Belongs to the peptidase S8 family
AMIR_RS30805	COG0583	DNA-binding transcription factor activity
AMIR_RS30835	COG3903	Transcriptional regulator
AMIR_RS30835	COG3629	intracellular signal transduction
AMIR_RS30855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMIR_RS30860	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS30865	COG1024	Enoyl-CoA hydratase
AMIR_RS30875	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS30885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMIR_RS30905	COG2197	response regulator
AMIR_RS30920	COG3469	chitinase activity
AMIR_RS30925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMIR_RS30935	COG0673	inositol 2-dehydrogenase activity
AMIR_RS30955	COG0386	Belongs to the glutathione peroxidase family
AMIR_RS30960	COG1760	l-serine dehydratase
AMIR_RS30965	COG0509	glycine decarboxylation via glycine cleavage system
AMIR_RS30970	COG0686	Belongs to the AlaDH PNT family
AMIR_RS30990	COG1132	(ABC) transporter
AMIR_RS30995	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIR_RS30995	COG0567	Dehydrogenase, E1 component
AMIR_RS31010	COG0667	Aldo Keto reductase
AMIR_RS31025	COG3903	Transcriptional regulator
AMIR_RS31025	COG3629	intracellular signal transduction
AMIR_RS31040	COG1228	amidohydrolase
AMIR_RS31055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMIR_RS31060	COG2986	histidine ammonia-lyase
AMIR_RS31080	COG1174	glycine betaine transport
AMIR_RS31120	COG5001	Diguanylate cyclase
AMIR_RS31130	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AMIR_RS31150	COG0406	alpha-ribazole phosphatase activity
AMIR_RS31175	COG1597	lipid kinase activity
AMIR_RS31190	COG5662	AntiSigma factor
AMIR_RS31195	COG1595	DNA-templated transcription, initiation
AMIR_RS31200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMIR_RS31210	COG2135	peptidase activity
AMIR_RS31215	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMIR_RS31220	COG1162	GTPase activity
AMIR_RS31245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMIR_RS31250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIR_RS31260	COG0653	protein targeting
AMIR_RS31265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMIR_RS31270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMIR_RS31275	COG5401	PFAM Sporulation and spore germination
AMIR_RS31280	COG5002	protein histidine kinase activity
AMIR_RS31285	COG0745	RESPONSE REGULATOR receiver
AMIR_RS31335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMIR_RS31340	COG0531	amino acid
AMIR_RS31350	COG1482	cell wall glycoprotein biosynthetic process
AMIR_RS31390	COG1994	Peptidase M50
AMIR_RS31395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AMIR_RS31400	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AMIR_RS31400	COG0778	Nitroreductase
AMIR_RS31415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMIR_RS31435	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS31455	COG0297	glycogen (starch) synthase activity
AMIR_RS31470	COG1316	TRANSCRIPTIONal
AMIR_RS31475	COG1316	TRANSCRIPTIONal
AMIR_RS31485	COG2259	Doxx family
AMIR_RS31510	COG2188	Transcriptional regulator
AMIR_RS31540	COG0582	viral genome integration into host DNA
AMIR_RS31565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AMIR_RS31570	COG2186	Transcriptional regulator
AMIR_RS31610	COG0483	inositol monophosphate 1-phosphatase activity
AMIR_RS31615	COG0745	RESPONSE REGULATOR receiver
AMIR_RS31620	COG2205	protein histidine kinase activity
AMIR_RS31655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMIR_RS31670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMIR_RS31685	COG0424	maF-like protein
AMIR_RS31690	COG1301	dicarboxylic acid transport
AMIR_RS31700	COG4770	biotin carboxylase activity
AMIR_RS31750	COG2197	response regulator
AMIR_RS31755	COG4585	Histidine kinase
AMIR_RS31770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMIR_RS31775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMIR_RS31780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMIR_RS31795	COG1473	amidohydrolase
AMIR_RS31795	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMIR_RS31825	COG0515	serine threonine protein kinase
AMIR_RS31835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMIR_RS31855	COG3654	unkown
AMIR_RS31875	COG2319	Wd-40 repeat
AMIR_RS31875	COG5635	Nacht domain
AMIR_RS31905	COG3903	Transcriptional regulator
AMIR_RS31905	COG3629	intracellular signal transduction
AMIR_RS31930	COG3883	PFAM NLP P60 protein
AMIR_RS31930	COG0791	NLP P60 protein
AMIR_RS31950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMIR_RS31975	COG1079	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS31980	COG4603	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS31985	COG3845	ABC transporter
AMIR_RS31990	COG1744	ABC transporter substrate-binding protein PnrA-like
AMIR_RS32030	COG2009	succinate dehydrogenase
AMIR_RS32045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMIR_RS32050	COG1686	Belongs to the peptidase S11 family
AMIR_RS32065	COG1295	ribonuclease BN
AMIR_RS32070	COG0180	Tryptophanyl-tRNA synthetase
AMIR_RS32080	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMIR_RS32095	COG0708	Exodeoxyribonuclease III
AMIR_RS32130	COG0484	heat shock protein binding
AMIR_RS32155	COG4555	ABC transporter
AMIR_RS32180	COG0039	L-malate dehydrogenase activity
AMIR_RS32210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMIR_RS32225	COG0138	bifunctional purine biosynthesis protein purh
AMIR_RS32250	COG0045	succinate-CoA ligase (ADP-forming) activity
AMIR_RS32305	COG2815	serine threonine protein kinase
AMIR_RS32305	COG0515	serine threonine protein kinase
AMIR_RS32310	COG0515	serine threonine protein kinase
AMIR_RS32315	COG0583	DNA-binding transcription factor activity
AMIR_RS32320	COG0697	spore germination
AMIR_RS32350	COG0519	Catalyzes the synthesis of GMP from XMP
AMIR_RS32350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMIR_RS32360	COG1012	belongs to the aldehyde dehydrogenase family
AMIR_RS32375	COG0516	GMP reductase activity
AMIR_RS32420	COG0459	protein refolding
AMIR_RS32425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMIR_RS32435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMIR_RS32440	COG0456	acetyltransferase
AMIR_RS32455	COG3118	belongs to the thioredoxin family
AMIR_RS32460	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS32480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMIR_RS32490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMIR_RS32515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMIR_RS32520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMIR_RS32525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMIR_RS32545	COG0443	Heat shock 70 kDa protein
AMIR_RS32555	COG1674	ftsk spoiiie
AMIR_RS32565	COG1404	Belongs to the peptidase S8 family
AMIR_RS32595	COG1404	Belongs to the peptidase S8 family
AMIR_RS32600	COG0101	tRNA pseudouridine synthase activity
AMIR_RS32605	COG0203	ribosomal protein L17
AMIR_RS32610	COG0202	RNA polymerase activity
AMIR_RS32615	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMIR_RS32620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMIR_RS32630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMIR_RS32635	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMIR_RS32655	COG0563	adenylate kinase activity
AMIR_RS32675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMIR_RS32680	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMIR_RS32690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMIR_RS32695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMIR_RS32700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMIR_RS32705	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMIR_RS32710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMIR_RS32715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMIR_RS32730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMIR_RS32735	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMIR_RS32740	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMIR_RS32745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMIR_RS32750	COG0089	rRNA binding
AMIR_RS32755	COG0088	Forms part of the polypeptide exit tunnel
AMIR_RS32760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMIR_RS32765	COG0051	transcription antitermination factor activity, RNA binding
AMIR_RS32770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMIR_RS32775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMIR_RS32780	COG0049	tRNA binding
AMIR_RS32785	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMIR_RS32815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMIR_RS32820	COG0085	RNA polymerase activity
AMIR_RS32850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMIR_RS32880	COG0081	regulation of translation
AMIR_RS32885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMIR_RS32895	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMIR_RS32905	COG0436	Aminotransferase
AMIR_RS32920	COG2030	dehydratase
AMIR_RS32925	COG2030	dehydratase
AMIR_RS32965	COG1666	GTP binding
AMIR_RS32970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AMIR_RS32980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIR_RS32985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIR_RS32990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIR_RS33000	COG1834	amidinotransferase
AMIR_RS33005	COG1522	sequence-specific DNA binding
AMIR_RS33015	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMIR_RS33015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMIR_RS33020	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMIR_RS33035	COG0142	geranyltranstransferase activity
AMIR_RS33040	COG1007	ATP synthesis coupled electron transport
AMIR_RS33055	COG0713	ATP synthesis coupled electron transport
AMIR_RS33065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIR_RS33070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMIR_RS33075	COG1034	ATP synthesis coupled electron transport
AMIR_RS33080	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMIR_RS33090	COG0649	NAD binding
AMIR_RS33095	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIR_RS33100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMIR_RS33115	COG2226	methyltransferase
AMIR_RS33120	COG0483	inositol monophosphate 1-phosphatase activity
AMIR_RS33130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMIR_RS33135	COG2151	metal-sulfur cluster biosynthetic enzyme
AMIR_RS33140	COG3396	Phenylacetate-CoA oxygenase
AMIR_RS33145	COG3460	Phenylacetate-CoA oxygenase
AMIR_RS33150	COG3396	Phenylacetate-CoA oxygenase
AMIR_RS33200	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AMIR_RS33250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMIR_RS33255	COG1333	cytochrome c biogenesis protein
AMIR_RS33260	COG0785	Cytochrome C biogenesis protein
AMIR_RS33280	COG0406	alpha-ribazole phosphatase activity
AMIR_RS33285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMIR_RS33325	COG0113	porphobilinogen synthase activity
AMIR_RS33335	COG0181	hydroxymethylbilane synthase activity
AMIR_RS33340	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMIR_RS33345	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AMIR_RS33365	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS33405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMIR_RS33440	COG5002	protein histidine kinase activity
AMIR_RS33445	COG0667	Aldo Keto reductase
AMIR_RS33455	COG0588	phosphoglycerate mutase activity
AMIR_RS33460	COG0318	PFAM AMP-dependent synthetase and ligase
AMIR_RS33475	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS33495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMIR_RS33525	COG3226	Transcriptional regulator
AMIR_RS33540	COG0693	protein deglycase activity
AMIR_RS33565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMIR_RS33570	COG2733	membrane
AMIR_RS33600	COG1136	(ABC) transporter
AMIR_RS33630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIR_RS33635	COG2364	Membrane
AMIR_RS33695	COG1278	Cold shock
AMIR_RS33700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIR_RS33715	COG2255	four-way junction helicase activity
AMIR_RS33795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMIR_RS33815	COG0456	acetyltransferase
AMIR_RS33820	COG0745	RESPONSE REGULATOR receiver
AMIR_RS33855	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AMIR_RS33860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AMIR_RS33875	COG0735	belongs to the Fur family
AMIR_RS33920	COG3962	Belongs to the TPP enzyme family
AMIR_RS33925	COG3718	enzyme involved in inositol metabolism
AMIR_RS33940	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMIR_RS33950	COG1082	Xylose isomerase domain protein TIM barrel
AMIR_RS33965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMIR_RS33980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMIR_RS34040	COG1063	alcohol dehydrogenase
AMIR_RS34045	COG5001	Diguanylate cyclase
AMIR_RS34045	COG3300	MHYT domain
AMIR_RS34075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMIR_RS34080	COG0047	phosphoribosylformylglycinamidine synthase activity
AMIR_RS34085	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMIR_RS34110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMIR_RS34120	COG0765	amino acid transport
AMIR_RS34135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMIR_RS34145	COG1595	DNA-templated transcription, initiation
AMIR_RS34160	COG1595	DNA-templated transcription, initiation
AMIR_RS34170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIR_RS34180	COG0436	Aminotransferase
AMIR_RS34225	COG0584	glycerophosphoryl diester phosphodiesterase
AMIR_RS34230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMIR_RS34235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMIR_RS34260	COG4129	membrane
AMIR_RS34280	COG0667	Aldo Keto reductase
AMIR_RS34285	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS34295	COG1595	DNA-templated transcription, initiation
AMIR_RS34320	COG0277	FAD linked oxidase domain protein
AMIR_RS34325	COG0586	Pfam SNARE associated Golgi protein
AMIR_RS34330	COG1072	(Pantothenic acid kinase))
AMIR_RS34335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIR_RS34365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMIR_RS34390	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS34400	COG0542	response to heat
AMIR_RS34410	COG2871	sodium ion transport
AMIR_RS34415	COG0789	Transcriptional regulator
AMIR_RS34420	COG0484	heat shock protein binding
AMIR_RS34425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMIR_RS34430	COG0443	Heat shock 70 kDa protein
AMIR_RS34450	COG2181	nitrate reductase activity
AMIR_RS34450	COG0247	lactate metabolic process
AMIR_RS34455	COG1950	PFAM Membrane protein of
AMIR_RS34480	COG0717	Belongs to the dCTP deaminase family
AMIR_RS34500	COG2197	response regulator
AMIR_RS34505	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS34520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMIR_RS34550	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS34570	COG1960	acyl-CoA dehydrogenase activity
AMIR_RS34580	COG1309	transcriptional regulator
AMIR_RS34585	COG0789	Transcriptional regulator
AMIR_RS34590	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMIR_RS34595	COG0022	dehydrogenase e1 component
AMIR_RS34605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMIR_RS34615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMIR_RS34620	COG0765	amino acid transport
AMIR_RS34655	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AMIR_RS34685	COG1940	carbohydrate kinase activity
AMIR_RS34710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMIR_RS34725	COG4585	Histidine kinase
AMIR_RS34730	COG2197	response regulator
AMIR_RS34735	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS34745	COG0561	phosphatase activity
AMIR_RS34750	COG0071	Belongs to the small heat shock protein (HSP20) family
AMIR_RS34760	COG4585	Histidine kinase
AMIR_RS34765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMIR_RS34785	COG1131	(ABC) transporter
AMIR_RS34800	COG0402	S-adenosylhomocysteine deaminase activity
AMIR_RS34805	COG4221	oxidoreductase activity
AMIR_RS34820	COG2814	Major facilitator Superfamily
AMIR_RS34825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMIR_RS34830	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS34850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMIR_RS34875	COG0360	Binds together with S18 to 16S ribosomal RNA
AMIR_RS34880	COG0629	single-stranded DNA binding
AMIR_RS34885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMIR_RS34890	COG0359	binds to the 23S rRNA
AMIR_RS34895	COG0305	Participates in initiation and elongation during chromosome replication
AMIR_RS34990	COG0702	epimerase
AMIR_RS34995	COG1063	alcohol dehydrogenase
AMIR_RS35005	COG0583	DNA-binding transcription factor activity
AMIR_RS35025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMIR_RS35030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMIR_RS35050	COG0495	leucyl-tRNA aminoacylation
AMIR_RS35070	COG2197	response regulator
AMIR_RS35075	COG0617	tRNA 3'-terminal CCA addition
AMIR_RS35095	COG0515	serine threonine protein kinase
AMIR_RS35100	COG1595	DNA-templated transcription, initiation
AMIR_RS35115	COG0492	ferredoxin-NADP+ reductase activity
AMIR_RS35115	COG3118	belongs to the thioredoxin family
AMIR_RS35120	COG3409	Peptidoglycan-binding domain 1 protein
AMIR_RS35120	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMIR_RS35130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMIR_RS35135	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMIR_RS35145	COG1192	Involved in chromosome partitioning
AMIR_RS35150	COG0357	Ribosomal RNA small subunit methyltransferase G
AMIR_RS35165	COG0706	membrane insertase activity
AMIR_RS35170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMIR_RS35175	COG0594	ribonuclease P activity
AMIR_RS35180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMIR_RS35205	COG2226	methyltransferase
AMIR_RS35280	COG0583	DNA-binding transcription factor activity
AMIR_RS35310	COG3629	intracellular signal transduction
AMIR_RS35310	COG3903	Transcriptional regulator
AMIR_RS35385	COG1404	Belongs to the peptidase S8 family
AMIR_RS35395	COG0671	phosphoesterase, PA-phosphatase related
AMIR_RS35525	COG1716	ATPase activity
AMIR_RS35525	COG5001	Diguanylate cyclase
AMIR_RS35535	COG2205	protein histidine kinase activity
AMIR_RS35590	COG5001	Diguanylate cyclase
AMIR_RS35670	COG2197	response regulator
AMIR_RS35675	COG3209	COG3209 Rhs family protein
AMIR_RS35700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMIR_RS35850	COG2909	trisaccharide binding
AMIR_RS35865	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS35865	COG1216	Glycosyl transferase, family 2
AMIR_RS35870	COG1132	(ABC) transporter
AMIR_RS35895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMIR_RS35960	COG1028	Short-chain dehydrogenase reductase Sdr
AMIR_RS35980	COG3629	intracellular signal transduction
AMIR_RS35980	COG3903	Transcriptional regulator
AMIR_RS36000	COG3831	ATPase activity
AMIR_RS36040	COG3209	COG3209 Rhs family protein
AMIR_RS36080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMIR_RS36095	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS36200	COG1132	(ABC) transporter
AMIR_RS36215	COG0438	transferase activity, transferring glycosyl groups
AMIR_RS36375	COG2340	Cysteine-rich secretory protein family
AMIR_RS36390	COG2259	Doxx family
AMIR_RS36510	COG1316	TRANSCRIPTIONal