locus-tag	class	description
CNX65_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CNX65_RS00010	COG0592	DNA-directed DNA polymerase activity
CNX65_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CNX65_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNX65_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CNX65_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNX65_RS00055	COG2259	Doxx family
CNX65_RS00075	COG0705	Rhomboid family
CNX65_RS00090	COG3764	Sortase (surface protein transpeptidase)
CNX65_RS00110	COG0515	serine threonine protein kinase
CNX65_RS00110	COG2815	serine threonine protein kinase
CNX65_RS00115	COG0515	serine threonine protein kinase
CNX65_RS00120	COG0768	penicillin binding
CNX65_RS00135	COG1716	ATPase activity
CNX65_RS00140	COG1716	ATPase activity
CNX65_RS00170	COG1309	transcriptional regulator
CNX65_RS00180	COG2211	Major facilitator Superfamily
CNX65_RS00185	COG0300	oxidoreductase activity
CNX65_RS00210	COG3281	Trehalose synthase
CNX65_RS00240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CNX65_RS00260	COG0405	Gamma-glutamyltransferase
CNX65_RS00290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_RS00305	COG2226	methyltransferase
CNX65_RS00340	COG3275	phosphorelay sensor kinase activity
CNX65_RS00350	COG3279	Response regulator of the LytR AlgR family
CNX65_RS00360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_RS00370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_RS00385	COG0584	glycerophosphoryl diester phosphodiesterase
CNX65_RS00400	COG0653	protein targeting
CNX65_RS00415	COG1528	Iron-storage protein
CNX65_RS00465	COG1271	oxidase subunit
CNX65_RS00470	COG1294	oxidase, subunit
CNX65_RS00480	COG4988	ABC transporter
CNX65_RS00495	COG0454	-acetyltransferase
CNX65_RS00520	COG1131	(ABC) transporter
CNX65_RS00525	COG1725	Transcriptional regulator
CNX65_RS00550	COG1501	Belongs to the glycosyl hydrolase 31 family
CNX65_RS00570	COG0754	glutathionylspermidine amidase activity
CNX65_RS00575	COG3766	membrane
CNX65_RS00585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CNX65_RS00605	COG0579	oxidoreductase
CNX65_RS00615	COG0561	phosphatase activity
CNX65_RS00625	COG0463	Glycosyl transferase, family 2
CNX65_RS00645	COG1216	Glycosyl transferase, family 2
CNX65_RS00665	COG1216	Glycosyl transferase, family 2
CNX65_RS00710	COG2234	aminopeptidase activity
CNX65_RS00720	COG0737	Belongs to the 5'-nucleotidase family
CNX65_RS00720	COG1525	nuclease
CNX65_RS00720	COG4085	toxin activity
CNX65_RS00740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX65_RS00765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNX65_RS00790	COG1686	Belongs to the peptidase S11 family
CNX65_RS00795	COG5295	Hep Hag repeat protein
CNX65_RS00795	COG4932	domain protein
CNX65_RS00840	COG0183	Belongs to the thiolase family
CNX65_RS00855	COG0287	Prephenate dehydrogenase
CNX65_RS00860	COG1473	amidohydrolase
CNX65_RS00930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CNX65_RS00935	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CNX65_RS00960	COG3629	intracellular signal transduction
CNX65_RS00960	COG3903	Transcriptional regulator
CNX65_RS00965	COG0747	negative chemotaxis
CNX65_RS00970	COG0601	transmembrane transport
CNX65_RS00975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_RS00980	COG0444	Belongs to the ABC transporter superfamily
CNX65_RS00985	COG4608	Belongs to the ABC transporter superfamily
CNX65_RS01025	COG1070	Carbohydrate kinase
CNX65_RS01030	COG1278	Cold shock
CNX65_RS01045	COG1764	response to oxidative stress
CNX65_RS01055	COG0431	NADPH-dependent FMN reductase
CNX65_RS01100	COG1408	metallophosphoesterase
CNX65_RS01160	COG0673	inositol 2-dehydrogenase activity
CNX65_RS01175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_RS01185	COG0592	DNA-directed DNA polymerase activity
CNX65_RS01210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNX65_RS01215	COG0494	nUDIX hydrolase
CNX65_RS01225	COG0596	Alpha beta hydrolase
CNX65_RS01235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNX65_RS01240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNX65_RS01255	COG3844	kynureninase activity
CNX65_RS01265	COG1522	sequence-specific DNA binding
CNX65_RS01270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CNX65_RS01275	COG1737	Transcriptional regulator
CNX65_RS01285	COG3876	Protein conserved in bacteria
CNX65_RS01290	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_RS01460	COG1205	dead DEAH box helicase
CNX65_RS01460	COG1111	helicase
CNX65_RS01465	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CNX65_RS01500	COG1754	DNA topoisomerase type I activity
CNX65_RS01500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNX65_RS01510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNX65_RS01515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CNX65_RS01535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CNX65_RS01540	COG1120	ATPase activity
CNX65_RS01580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CNX65_RS01585	COG2027	D-alanyl-D-alanine carboxypeptidase
CNX65_RS01595	COG0037	tRNA processing
CNX65_RS01600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CNX65_RS01610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNX65_RS01615	COG0302	gtp cyclohydrolase
CNX65_RS01620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNX65_RS01625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CNX65_RS01645	COG0649	NAD binding
CNX65_RS01670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CNX65_RS01675	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CNX65_RS01680	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CNX65_RS01690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CNX65_RS01700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS01705	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS01710	COG1120	ATPase activity
CNX65_RS01725	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CNX65_RS01735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNX65_RS01760	COG1194	a g-specific adenine glycosylase
CNX65_RS01775	COG1609	Transcriptional regulator
CNX65_RS01785	COG1653	transport
CNX65_RS01790	COG1175	transmembrane transport
CNX65_RS01795	COG3833	ABC-type maltose transport systems, permease component
CNX65_RS01800	COG3842	ATPase activity
CNX65_RS01810	COG1121	(ABC) transporter
CNX65_RS01815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CNX65_RS01850	COG0215	cysteine-tRNA ligase activity
CNX65_RS01860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CNX65_RS01865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CNX65_RS01870	COG1329	Transcriptional regulator
CNX65_RS01890	COG4221	oxidoreductase activity
CNX65_RS01905	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CNX65_RS01940	COG2205	protein histidine kinase activity
CNX65_RS01945	COG0745	RESPONSE REGULATOR receiver
CNX65_RS01975	COG3629	intracellular signal transduction
CNX65_RS01975	COG3903	Transcriptional regulator
CNX65_RS01995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS02000	COG0583	DNA-binding transcription factor activity
CNX65_RS02015	COG1404	Belongs to the peptidase S8 family
CNX65_RS02020	COG0179	Fumarylacetoacetate (FAA) hydrolase
CNX65_RS02025	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_RS02030	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS02050	COG2186	Transcriptional regulator
CNX65_RS02055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CNX65_RS02060	COG0395	ABC-type sugar transport system, permease component
CNX65_RS02065	COG1175	transmembrane transport
CNX65_RS02070	COG2182	Extracellular solute-binding protein
CNX65_RS02075	COG2188	Transcriptional regulator
CNX65_RS02080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_RS02085	COG3384	dioxygenase
CNX65_RS02090	COG0352	thiamine-phosphate diphosphorylase activity
CNX65_RS02095	COG2022	thiamine diphosphate biosynthetic process
CNX65_RS02095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNX65_RS02105	COG2022	thiamine diphosphate biosynthetic process
CNX65_RS02115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS02150	COG0351	phosphomethylpyrimidine kinase
CNX65_RS02155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CNX65_RS02180	COG1802	Transcriptional regulator
CNX65_RS02185	COG1902	pentaerythritol trinitrate reductase activity
CNX65_RS02190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNX65_RS02210	COG0688	phosphatidylethanolamine metabolic process
CNX65_RS02230	COG1278	Cold shock
CNX65_RS02240	COG0459	protein refolding
CNX65_RS02260	COG3142	Participates in the control of copper homeostasis
CNX65_RS02270	COG1175	transmembrane transport
CNX65_RS02275	COG0395	ABC-type sugar transport system, permease component
CNX65_RS02280	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CNX65_RS02295	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_RS02330	COG2018	Roadblock/LC7 domain
CNX65_RS02370	COG0315	cyclic pyranopterin monophosphate synthase activity
CNX65_RS02370	COG0521	Mo-molybdopterin cofactor biosynthetic process
CNX65_RS02380	COG1388	LysM domain
CNX65_RS02390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CNX65_RS02395	COG1846	Transcriptional regulator
CNX65_RS02420	COG3304	Inner membrane component domain
CNX65_RS02450	COG1278	Cold shock
CNX65_RS02460	COG2814	Major facilitator Superfamily
CNX65_RS02485	COG2252	PERMEase
CNX65_RS02495	COG2814	Major facilitator Superfamily
CNX65_RS02510	COG0488	(ABC) transporter
CNX65_RS02525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNX65_RS02535	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_RS02535	COG1506	peptidase
CNX65_RS02550	COG0259	pyridoxamine-phosphate oxidase activity
CNX65_RS02555	COG0829	nickel cation binding
CNX65_RS02565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CNX65_RS02575	COG0804	urea catabolic process
CNX65_RS02580	COG0832	Belongs to the urease beta subunit family
CNX65_RS02585	COG0831	urea catabolic process
CNX65_RS02610	COG2197	response regulator
CNX65_RS02640	COG1132	(ABC) transporter
CNX65_RS02645	COG1132	(ABC) transporter
CNX65_RS02650	COG0531	amino acid
CNX65_RS02655	COG2017	converts alpha-aldose to the beta-anomer
CNX65_RS02660	COG1228	amidohydrolase
CNX65_RS02665	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS02685	COG0415	Belongs to the DNA photolyase family
CNX65_RS02690	COG2197	response regulator
CNX65_RS02700	COG1668	transmembrane transport
CNX65_RS02705	COG4152	abc transporter atp-binding protein
CNX65_RS02735	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_RS02740	COG2130	NADP-dependent
CNX65_RS02755	COG1674	ftsk spoiiie
CNX65_RS02790	COG2267	carboxylic ester hydrolase activity
CNX65_RS02795	COG0583	DNA-binding transcription factor activity
CNX65_RS02800	COG0384	phenazine biosynthesis protein PhzF
CNX65_RS02810	COG0702	epimerase
CNX65_RS02815	COG1733	regulation of RNA biosynthetic process
CNX65_RS02855	COG2197	response regulator
CNX65_RS02865	COG2319	Wd-40 repeat
CNX65_RS02865	COG4249	Peptidase C14 caspase catalytic subunit p20
CNX65_RS02910	COG3209	COG3209 Rhs family protein
CNX65_RS02985	COG2197	response regulator
CNX65_RS02995	COG0778	Nitroreductase
CNX65_RS03000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CNX65_RS03005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNX65_RS03015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CNX65_RS03020	COG0588	phosphoglycerate mutase activity
CNX65_RS03045	COG2205	protein histidine kinase activity
CNX65_RS03055	COG0395	ABC-type sugar transport system, permease component
CNX65_RS03060	COG1175	transmembrane transport
CNX65_RS03065	COG1653	transport
CNX65_RS03075	COG1349	DNA-binding transcription factor activity
CNX65_RS03085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNX65_RS03090	COG0521	Mo-molybdopterin cofactor biosynthetic process
CNX65_RS03090	COG0315	cyclic pyranopterin monophosphate synthase activity
CNX65_RS03095	COG1970	mechanosensitive ion channel activity
CNX65_RS03110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CNX65_RS03115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CNX65_RS03125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNX65_RS03145	COG0515	serine threonine protein kinase
CNX65_RS03170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_RS03175	COG0084	hydrolase, TatD family'
CNX65_RS03180	COG3583	domain protein
CNX65_RS03185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CNX65_RS03190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNX65_RS03195	COG2011	ABC-type metal ion transport system permease component
CNX65_RS03205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CNX65_RS03210	COG0488	(ABC) transporter
CNX65_RS03215	COG3599	regulation of cell shape
CNX65_RS03230	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS03235	COG0193	aminoacyl-tRNA hydrolase activity
CNX65_RS03255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CNX65_RS03280	COG1309	transcriptional regulator
CNX65_RS03290	COG2133	pyrroloquinoline quinone binding
CNX65_RS03310	COG3956	TIGRFAM MazG family protein
CNX65_RS03315	COG0793	Belongs to the peptidase S41A family
CNX65_RS03315	COG4946	Tricorn protease homolog
CNX65_RS03330	COG0148	phosphopyruvate hydratase activity
CNX65_RS03365	COG4166	transmembrane transport
CNX65_RS03370	COG0601	transmembrane transport
CNX65_RS03375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_RS03385	COG4608	Belongs to the ABC transporter superfamily
CNX65_RS03410	COG0714	Associated with various cellular activities
CNX65_RS03480	COG0183	Belongs to the thiolase family
CNX65_RS03510	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CNX65_RS03520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNX65_RS03530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CNX65_RS03545	COG1331	Highly conserved protein containing a thioredoxin domain
CNX65_RS03570	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CNX65_RS03580	COG1793	dna ligase
CNX65_RS03585	COG0114	fumarate hydratase activity
CNX65_RS03590	COG0492	ferredoxin-NADP+ reductase activity
CNX65_RS03610	COG1722	exodeoxyribonuclease VII activity
CNX65_RS03620	COG1570	exodeoxyribonuclease VII activity
CNX65_RS03650	COG0419	ATPase involved in DNA repair
CNX65_RS03665	COG0012	GTP binding
CNX65_RS03675	COG1051	belongs to the nudix hydrolase family
CNX65_RS03680	COG2154	pterin-4-alpha-carbinolamine dehydratase
CNX65_RS03690	COG4149	molybdate abc transporter
CNX65_RS03695	COG3842	ATPase activity
CNX65_RS03710	COG1131	(ABC) transporter
CNX65_RS03730	COG0494	nUDIX hydrolase
CNX65_RS03735	COG0180	Tryptophanyl-tRNA synthetase
CNX65_RS03745	COG1217	gtp-binding protein TYPA
CNX65_RS03750	COG0747	negative chemotaxis
CNX65_RS03755	COG4166	transmembrane transport
CNX65_RS03775	COG4608	Belongs to the ABC transporter superfamily
CNX65_RS03780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CNX65_RS03815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_RS03820	COG1611	Belongs to the LOG family
CNX65_RS03825	COG1611	Belongs to the LOG family
CNX65_RS03835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNX65_RS03855	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_RS03880	COG1024	Enoyl-CoA hydratase
CNX65_RS03885	COG3327	negative regulation of DNA-templated transcription, initiation
CNX65_RS03895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNX65_RS03905	COG2814	Major facilitator Superfamily
CNX65_RS03920	COG0297	glycogen (starch) synthase activity
CNX65_RS03925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CNX65_RS03940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNX65_RS03945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CNX65_RS03965	COG2239	Acts as a magnesium transporter
CNX65_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS04030	COG0598	Magnesium transport protein CorA
CNX65_RS04065	COG0513	Belongs to the DEAD box helicase family
CNX65_RS04100	COG2267	carboxylic ester hydrolase activity
CNX65_RS04120	COG0243	molybdopterin cofactor binding
CNX65_RS04125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_RS04130	COG2223	nitrite transmembrane transporter activity
CNX65_RS04135	COG2146	nitrite reductase [NAD(P)H] activity
CNX65_RS04135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_RS04140	COG2146	nitrite reductase [NAD(P)H] activity
CNX65_RS04140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_RS04160	COG0745	RESPONSE REGULATOR receiver
CNX65_RS04180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_RS04205	COG0210	DNA helicase
CNX65_RS04220	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS04225	COG0583	DNA-binding transcription factor activity
CNX65_RS04265	COG0612	Peptidase, M16
CNX65_RS04275	COG1846	Transcriptional regulator
CNX65_RS04275	COG1940	carbohydrate kinase activity
CNX65_RS04305	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CNX65_RS04350	COG0431	NADPH-dependent FMN reductase
CNX65_RS04390	COG0791	NLP P60 protein
CNX65_RS04410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CNX65_RS04430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CNX65_RS04450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNX65_RS04450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CNX65_RS04455	COG0174	glutamine synthetase
CNX65_RS04485	COG1522	sequence-specific DNA binding
CNX65_RS04495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNX65_RS04495	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_RS04510	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CNX65_RS04585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CNX65_RS04615	COG1615	UPF0182 protein
CNX65_RS04645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CNX65_RS04650	COG2884	Cell division ATP-binding protein ftsE
CNX65_RS04655	COG2177	Part of the ABC transporter FtsEX involved in
CNX65_RS04660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CNX65_RS04665	COG2197	response regulator
CNX65_RS04670	COG4585	Histidine kinase
CNX65_RS04690	COG1643	Atp-dependent helicase
CNX65_RS04700	COG0456	acetyltransferase
CNX65_RS04700	COG0454	-acetyltransferase
CNX65_RS04705	COG2814	Major facilitator Superfamily
CNX65_RS04715	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CNX65_RS04775	COG1469	GTP cyclohydrolase I activity
CNX65_RS04780	COG0720	synthase
CNX65_RS04785	COG0602	queuosine metabolic process
CNX65_RS04790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CNX65_RS04845	COG0514	ATP-dependent DNA helicase (RecQ)
CNX65_RS04850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CNX65_RS04850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CNX65_RS04880	COG1175	transmembrane transport
CNX65_RS04885	COG0395	ABC-type sugar transport system, permease component
CNX65_RS04895	COG3254	rhamnose metabolic process
CNX65_RS04900	COG1609	Transcriptional regulator
CNX65_RS04905	COG3629	intracellular signal transduction
CNX65_RS04905	COG3903	Transcriptional regulator
CNX65_RS04935	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CNX65_RS04940	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CNX65_RS04945	COG0235	Class ii aldolase
CNX65_RS04950	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CNX65_RS04960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNX65_RS04965	COG3830	Belongs to the UPF0237 family
CNX65_RS04965	COG0560	Phosphoserine phosphatase
CNX65_RS05020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CNX65_RS05030	COG1335	isochorismatase
CNX65_RS05035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CNX65_RS05075	COG1234	tRNA 3'-trailer cleavage
CNX65_RS05080	COG3386	PFAM SMP-30 Gluconolaconase
CNX65_RS05090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CNX65_RS05095	COG1234	tRNA 3'-trailer cleavage
CNX65_RS05115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CNX65_RS05120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CNX65_RS05140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS05145	COG2072	flavoprotein involved in K transport
CNX65_RS05150	COG0586	Pfam SNARE associated Golgi protein
CNX65_RS05200	COG2949	membrane
CNX65_RS05205	COG1316	TRANSCRIPTIONal
CNX65_RS05220	COG4213	ABC transporter substrate-binding protein
CNX65_RS05230	COG1278	Cold shock
CNX65_RS05240	COG3345	alpha-galactosidase
CNX65_RS05250	COG4279	zinc finger
CNX65_RS05255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CNX65_RS05295	COG1376	ErfK ybiS ycfS ynhG family protein
CNX65_RS05300	COG0488	(ABC) transporter
CNX65_RS05310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CNX65_RS05320	COG4977	sequence-specific DNA binding
CNX65_RS05340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNX65_RS05340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNX65_RS05355	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS05365	COG1846	Transcriptional regulator
CNX65_RS05370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CNX65_RS05385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX65_RS05385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX65_RS05420	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_RS05425	COG0506	proline dehydrogenase activity
CNX65_RS05430	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS05440	COG0706	membrane insertase activity
CNX65_RS05465	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS05515	COG0740	serine-type endopeptidase activity
CNX65_RS05520	COG0740	serine-type endopeptidase activity
CNX65_RS05570	COG1609	Transcriptional regulator
CNX65_RS05575	COG2223	nitrite transmembrane transporter activity
CNX65_RS05585	COG3336	cytochrome c oxidase
CNX65_RS05620	COG2902	Dehydrogenase
CNX65_RS05645	COG0366	Alpha amylase catalytic
CNX65_RS05655	COG0668	transmembrane transport
CNX65_RS05660	COG1505	serine-type exopeptidase activity
CNX65_RS05680	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CNX65_RS05690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CNX65_RS05720	COG4552	Acetyltransferase involved in intracellular survival and related
CNX65_RS05740	COG0583	DNA-binding transcription factor activity
CNX65_RS05745	COG0544	peptidyl-prolyl cis-trans isomerase activity
CNX65_RS05750	COG0740	serine-type endopeptidase activity
CNX65_RS05755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CNX65_RS05770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CNX65_RS05805	COG0525	valine-tRNA ligase activity
CNX65_RS05810	COG0285	dihydrofolate synthase activity
CNX65_RS05840	COG0105	UTP biosynthetic process
CNX65_RS05845	COG1131	(ABC) transporter
CNX65_RS05855	COG0842	Transport permease protein
CNX65_RS05910	COG1530	ribonuclease E activity
CNX65_RS05910	COG1530	ribonuclease E activity
CNX65_RS05915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CNX65_RS05920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CNX65_RS05925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CNX65_RS05935	COG0477	Major facilitator Superfamily
CNX65_RS05950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CNX65_RS05965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CNX65_RS05970	COG0799	negative regulation of ribosome biogenesis
CNX65_RS05980	COG2755	lipolytic protein G-D-S-L family
CNX65_RS05985	COG1307	EDD domain protein, DegV family
CNX65_RS05990	COG1555	photosystem II stabilization
CNX65_RS05990	COG1596	polysaccharide export
CNX65_RS05995	COG2333	competence protein COMEC
CNX65_RS05995	COG0658	competence protein
CNX65_RS06015	COG0268	Binds directly to 16S ribosomal RNA
CNX65_RS06045	COG2308	Evidence 4 Homologs of previously reported genes of
CNX65_RS06055	COG1305	Transglutaminase-like
CNX65_RS06065	COG0481	GTPase activity
CNX65_RS06080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNX65_RS06100	COG0531	amino acid
CNX65_RS06110	COG0604	alcohol dehydrogenase
CNX65_RS06125	COG2732	(Barnase) inhibitor
CNX65_RS06140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_RS06145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CNX65_RS06190	COG0484	heat shock protein binding
CNX65_RS06210	COG0596	Alpha beta hydrolase
CNX65_RS06215	COG0537	adenosine 5'-monophosphoramidase activity
CNX65_RS06230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CNX65_RS06250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CNX65_RS06255	COG1381	Involved in DNA repair and RecF pathway recombination
CNX65_RS06260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CNX65_RS06275	COG0701	Predicted permease
CNX65_RS06300	COG0423	glycine-tRNA ligase activity
CNX65_RS06325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CNX65_RS06335	COG3340	Belongs to the peptidase S51 family
CNX65_RS06340	COG1595	DNA-templated transcription, initiation
CNX65_RS06345	COG0358	DNA primase activity
CNX65_RS06375	COG0582	viral genome integration into host DNA
CNX65_RS06400	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_RS06410	COG1733	regulation of RNA biosynthetic process
CNX65_RS06420	COG1316	TRANSCRIPTIONal
CNX65_RS06430	COG0726	polysaccharide deacetylase
CNX65_RS06440	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CNX65_RS06450	COG5001	Diguanylate cyclase
CNX65_RS06465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNX65_RS06470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNX65_RS06480	COG2084	Dehydrogenase
CNX65_RS06515	COG1132	(ABC) transporter
CNX65_RS06520	COG1132	(ABC) transporter
CNX65_RS06530	COG0515	serine threonine protein kinase
CNX65_RS06545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNX65_RS06550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_RS06570	COG3201	nicotinamide mononucleotide transporter
CNX65_RS06575	COG1653	transport
CNX65_RS06585	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CNX65_RS06625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CNX65_RS06645	COG0321	lipoyl(octanoyl) transferase activity
CNX65_RS06660	COG0702	epimerase
CNX65_RS06675	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_RS06680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNX65_RS06705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CNX65_RS06710	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CNX65_RS06730	COG0667	Aldo Keto reductase
CNX65_RS06765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CNX65_RS06775	COG0204	Acyl-transferase
CNX65_RS06775	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS06780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNX65_RS06795	COG1845	cytochrome c oxidase, subunit III
CNX65_RS06800	COG2010	Cytochrome c
CNX65_RS06810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CNX65_RS06840	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS06865	COG0003	Pfam Anion-transporting ATPase
CNX65_RS06875	COG1940	carbohydrate kinase activity
CNX65_RS06905	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CNX65_RS06930	COG0142	geranyltranstransferase activity
CNX65_RS06940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNX65_RS06965	COG0442	prolyl-tRNA aminoacylation
CNX65_RS07000	COG1201	RNA secondary structure unwinding
CNX65_RS07010	COG0443	Heat shock 70 kDa protein
CNX65_RS07015	COG2814	Major facilitator Superfamily
CNX65_RS07030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CNX65_RS07035	COG2137	regulation of response to DNA damage stimulus
CNX65_RS07045	COG0800	Aldolase
CNX65_RS07085	COG0789	Transcriptional regulator
CNX65_RS07090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNX65_RS07095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CNX65_RS07105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNX65_RS07115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CNX65_RS07130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CNX65_RS07135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CNX65_RS07145	COG1196	nuclear chromosome segregation
CNX65_RS07155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNX65_RS07160	COG2358	TRAP transporter, solute receptor (TAXI family
CNX65_RS07165	COG0642	Histidine kinase
CNX65_RS07170	COG0745	RESPONSE REGULATOR receiver
CNX65_RS07175	COG1126	abc transporter atp-binding protein
CNX65_RS07185	COG0765	amino acid transport
CNX65_RS07190	COG0765	amino acid transport
CNX65_RS07220	COG1515	deoxyribonuclease V activity
CNX65_RS07225	COG1486	melibiose metabolic process
CNX65_RS07230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CNX65_RS07235	COG2936	dipeptidyl-peptidase activity
CNX65_RS07245	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_RS07245	COG1506	peptidase
CNX65_RS07245	COG4946	Tricorn protease homolog
CNX65_RS07250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CNX65_RS07260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CNX65_RS07280	COG0123	including yeast histone deacetylase and acetoin utilization protein
CNX65_RS07290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_RS07295	COG2188	Transcriptional regulator
CNX65_RS07315	COG1690	Belongs to the RtcB family
CNX65_RS07355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_RS07365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNX65_RS07370	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_RS07400	COG1490	D-aminoacyl-tRNA deacylase activity
CNX65_RS07405	COG2890	protein-(glutamine-N5) methyltransferase activity
CNX65_RS07425	COG2313	pseudouridylate synthase activity
CNX65_RS07440	COG1061	Type III restriction enzyme res subunit
CNX65_RS07445	COG4213	ABC transporter substrate-binding protein
CNX65_RS07455	COG4214	carbohydrate transport
CNX65_RS07505	COG0756	dUTP diphosphatase activity
CNX65_RS07535	COG0569	domain protein
CNX65_RS07540	COG0531	amino acid
CNX65_RS07545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CNX65_RS07550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNX65_RS07560	COG0745	RESPONSE REGULATOR receiver
CNX65_RS07565	COG2205	protein histidine kinase activity
CNX65_RS07655	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_RS07655	COG1024	Enoyl-CoA hydratase
CNX65_RS07660	COG0183	Belongs to the thiolase family
CNX65_RS07680	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CNX65_RS07685	COG2197	response regulator
CNX65_RS07700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CNX65_RS07705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CNX65_RS07710	COG3253	May function as heme-dependent peroxidase
CNX65_RS07715	COG1404	Belongs to the peptidase S8 family
CNX65_RS07720	COG1404	Belongs to the peptidase S8 family
CNX65_RS07735	COG3220	belongs to the UPF0276 family
CNX65_RS07770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNX65_RS07790	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS07795	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS07800	COG3285	dna ligase
CNX65_RS07800	COG1793	dna ligase
CNX65_RS07825	COG5006	permease, DMT superfamily
CNX65_RS07830	COG1793	dna ligase
CNX65_RS07850	COG0488	(ABC) transporter
CNX65_RS07860	COG2706	6-phosphogluconolactonase activity
CNX65_RS07865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNX65_RS07890	COG1316	TRANSCRIPTIONal
CNX65_RS07900	COG0671	phosphoesterase, PA-phosphatase related
CNX65_RS07910	COG0653	protein targeting
CNX65_RS07925	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS07950	COG1309	transcriptional regulator
CNX65_RS08000	COG0475	glutathione-regulated potassium exporter activity
CNX65_RS08020	COG1160	GTP binding
CNX65_RS08025	COG2197	response regulator
CNX65_RS08050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CNX65_RS08060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNX65_RS08065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_RS08075	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS08085	COG1215	transferase activity, transferring glycosyl groups
CNX65_RS08105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNX65_RS08120	COG1131	(ABC) transporter
CNX65_RS08130	COG2197	response regulator
CNX65_RS08145	COG3851	Histidine kinase
CNX65_RS08150	COG2197	response regulator
CNX65_RS08295	COG0328	RNA-DNA hybrid ribonuclease activity
CNX65_RS08310	COG3345	alpha-galactosidase
CNX65_RS08360	COG1940	carbohydrate kinase activity
CNX65_RS08380	COG0601	transmembrane transport
CNX65_RS08390	COG0444	Belongs to the ABC transporter superfamily
CNX65_RS08420	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CNX65_RS08425	COG2318	DinB family
CNX65_RS08430	COG2255	four-way junction helicase activity
CNX65_RS08435	COG0632	four-way junction helicase activity
CNX65_RS08465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNX65_RS08470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CNX65_RS08475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNX65_RS08490	COG0124	histidyl-tRNA synthetase
CNX65_RS08540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNX65_RS08575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CNX65_RS08590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CNX65_RS08595	COG2205	protein histidine kinase activity
CNX65_RS08600	COG0745	RESPONSE REGULATOR receiver
CNX65_RS08615	COG2372	response to copper ion
CNX65_RS08655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_RS08670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_RS08700	COG2244	polysaccharide biosynthetic process
CNX65_RS08785	COG0667	Aldo Keto reductase
CNX65_RS08790	COG0596	Alpha beta hydrolase
CNX65_RS08790	COG2226	methyltransferase
CNX65_RS08790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNX65_RS08795	COG1024	Enoyl-CoA hydratase
CNX65_RS08815	COG1295	ribonuclease BN
CNX65_RS08825	COG3547	Transposase (IS116 IS110 IS902 family)
CNX65_RS08835	COG1126	abc transporter atp-binding protein
CNX65_RS08840	COG0765	amino acid transport
CNX65_RS08850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNX65_RS08885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNX65_RS08905	COG0395	ABC-type sugar transport system, permease component
CNX65_RS08910	COG2723	6-phospho-beta-galactosidase activity
CNX65_RS08920	COG4115	mRNA cleavage
CNX65_RS08925	COG2161	toxin-antitoxin pair type II binding
CNX65_RS08935	COG5416	Lipopolysaccharide assembly protein A domain
CNX65_RS08940	COG2319	Wd-40 repeat
CNX65_RS08940	COG4249	Peptidase C14 caspase catalytic subunit p20
CNX65_RS08955	COG2115	Belongs to the xylose isomerase family
CNX65_RS08960	COG1070	Carbohydrate kinase
CNX65_RS08965	COG0655	NAD(P)H dehydrogenase (quinone) activity
CNX65_RS08995	COG3708	Transcriptional regulator
CNX65_RS08995	COG2207	Transcriptional regulator
CNX65_RS09045	COG0640	Transcriptional regulator
CNX65_RS09085	COG0791	NLP P60 protein
CNX65_RS09100	COG1609	Transcriptional regulator
CNX65_RS09105	COG1609	Transcriptional regulator
CNX65_RS09110	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_RS09120	COG3458	cephalosporin-C deacetylase activity
CNX65_RS09175	COG0492	ferredoxin-NADP+ reductase activity
CNX65_RS09190	COG1609	Transcriptional regulator
CNX65_RS09200	COG4677	pectinesterase activity
CNX65_RS09210	COG0395	ABC-type sugar transport system, permease component
CNX65_RS09220	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_RS09250	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_RS09255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_RS09265	COG1879	ABC-type sugar transport system periplasmic component
CNX65_RS09280	COG3940	Belongs to the glycosyl hydrolase 43 family
CNX65_RS09290	COG1609	Transcriptional regulator
CNX65_RS09305	COG2160	L-arabinose isomerase activity
CNX65_RS09320	COG4214	carbohydrate transport
CNX65_RS09330	COG3401	FG-GAP repeat protein
CNX65_RS09345	COG1609	Transcriptional regulator
CNX65_RS09370	COG2356	endonuclease I
CNX65_RS09380	COG4585	Histidine kinase
CNX65_RS09400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CNX65_RS09405	COG4715	Zinc finger, swim domain protein
CNX65_RS09410	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CNX65_RS09425	COG0714	Associated with various cellular activities
CNX65_RS09430	COG3831	ATPase activity
CNX65_RS09435	COG3831	ATPase activity
CNX65_RS09445	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS09470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CNX65_RS09485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNX65_RS09490	COG2326	polyphosphate kinase activity
CNX65_RS09495	COG2261	transglycosylase associated protein
CNX65_RS09580	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CNX65_RS09585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CNX65_RS09590	COG0515	serine threonine protein kinase
CNX65_RS09590	COG2815	serine threonine protein kinase
CNX65_RS09600	COG2755	lipolytic protein G-D-S-L family
CNX65_RS09600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNX65_RS09610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CNX65_RS09630	COG1175	transmembrane transport
CNX65_RS09635	COG0395	ABC-type sugar transport system, permease component
CNX65_RS09645	COG0702	epimerase
CNX65_RS09655	COG0745	RESPONSE REGULATOR receiver
CNX65_RS09675	COG2197	response regulator
CNX65_RS09680	COG4585	Histidine kinase
CNX65_RS09690	COG1131	(ABC) transporter
CNX65_RS09790	COG2124	cytochrome p450
CNX65_RS09795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNX65_RS09815	COG1846	Transcriptional regulator
CNX65_RS09835	COG2197	response regulator
CNX65_RS09855	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_RS09855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNX65_RS09885	COG0395	ABC-type sugar transport system, permease component
CNX65_RS09890	COG4209	transmembrane transport
CNX65_RS09900	COG1609	Transcriptional regulator
CNX65_RS09910	COG0542	response to heat
CNX65_RS09940	COG1011	Hydrolase
CNX65_RS09955	COG1295	ribonuclease BN
CNX65_RS09965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CNX65_RS09970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CNX65_RS09985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CNX65_RS09995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CNX65_RS10010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CNX65_RS10030	COG3851	Histidine kinase
CNX65_RS10035	COG2197	response regulator
CNX65_RS10050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_RS10080	COG1595	DNA-templated transcription, initiation
CNX65_RS10170	COG1660	Displays ATPase and GTPase activities
CNX65_RS10345	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CNX65_RS10410	COG2181	nitrate reductase activity
CNX65_RS10415	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CNX65_RS10420	COG1140	nitrate reductase beta subunit
CNX65_RS10465	COG3250	beta-galactosidase activity
CNX65_RS10475	COG1732	Glycine betaine
CNX65_RS10480	COG1174	glycine betaine transport
CNX65_RS10490	COG1174	glycine betaine transport
CNX65_RS10515	COG3842	ATPase activity
CNX65_RS10535	COG0590	tRNA wobble adenosine to inosine editing
CNX65_RS10545	COG3835	regulator
CNX65_RS10575	COG0492	ferredoxin-NADP+ reductase activity
CNX65_RS10585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CNX65_RS10600	COG0531	amino acid
CNX65_RS10610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CNX65_RS10625	COG2186	Transcriptional regulator
CNX65_RS10645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CNX65_RS10660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CNX65_RS10665	COG1560	Kdo2-lipid A biosynthetic process
CNX65_RS10670	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS10695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNX65_RS10705	COG1953	Uracil, thiamine, allantoin
CNX65_RS10740	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CNX65_RS10745	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CNX65_RS10750	COG0217	transcriptional regulatory protein
CNX65_RS10765	COG1309	transcriptional regulator
CNX65_RS10770	COG0477	Major facilitator Superfamily
CNX65_RS10780	COG2124	cytochrome p450
CNX65_RS10815	COG3572	ergothioneine biosynthetic process
CNX65_RS10820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CNX65_RS10825	COG0121	glutamine amidotransferase
CNX65_RS10830	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CNX65_RS10875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CNX65_RS10905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNX65_RS10915	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS10920	COG3883	PFAM NLP P60 protein
CNX65_RS10920	COG0791	NLP P60 protein
CNX65_RS10935	COG0746	molybdenum cofactor guanylyltransferase activity
CNX65_RS10940	COG0500	methyltransferase
CNX65_RS10945	COG0714	Associated with various cellular activities
CNX65_RS10955	COG2304	oxidoreductase activity
CNX65_RS10970	COG5002	protein histidine kinase activity
CNX65_RS11050	COG3012	SEC-C Motif Domain Protein
CNX65_RS11060	COG4733	cellulase activity
CNX65_RS11060	COG5297	Belongs to the glycosyl hydrolase family 6
CNX65_RS11065	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_RS11080	COG4209	transmembrane transport
CNX65_RS11085	COG0395	ABC-type sugar transport system, permease component
CNX65_RS11100	COG1324	tolerance protein
CNX65_RS11105	COG0789	Transcriptional regulator
CNX65_RS11120	COG0247	lactate metabolic process
CNX65_RS11120	COG0277	FAD linked oxidase domain protein
CNX65_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS11130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CNX65_RS11135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CNX65_RS11150	COG4221	oxidoreductase activity
CNX65_RS11175	COG5297	Belongs to the glycosyl hydrolase family 6
CNX65_RS11180	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CNX65_RS11205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CNX65_RS11210	COG0215	cysteine-tRNA ligase activity
CNX65_RS11240	COG0745	RESPONSE REGULATOR receiver
CNX65_RS11245	COG0745	RESPONSE REGULATOR receiver
CNX65_RS11250	COG5002	protein histidine kinase activity
CNX65_RS11260	COG0646	methionine synthase
CNX65_RS11260	COG1410	methionine synthase
CNX65_RS11265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNX65_RS11285	COG0300	oxidoreductase activity
CNX65_RS11295	COG0140	phosphoribosyl-ATP diphosphatase activity
CNX65_RS11300	COG0679	Auxin Efflux Carrier
CNX65_RS11315	COG1994	Peptidase M50
CNX65_RS11315	COG0517	IMP dehydrogenase activity
CNX65_RS11320	COG2197	response regulator
CNX65_RS11350	COG1222	aaa ATPase
CNX65_RS11355	COG2197	response regulator
CNX65_RS11360	COG4585	Histidine kinase
CNX65_RS11400	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CNX65_RS11405	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CNX65_RS11410	COG4221	oxidoreductase activity
CNX65_RS11430	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CNX65_RS11450	COG2378	regulation of single-species biofilm formation
CNX65_RS11460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CNX65_RS11515	COG3706	GGDEF domain
CNX65_RS11540	COG2357	RelA SpoT domain protein
CNX65_RS11555	COG2353	YceI-like domain
CNX65_RS11560	COG1846	Transcriptional regulator
CNX65_RS11565	COG0714	Associated with various cellular activities
CNX65_RS11575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNX65_RS11585	COG1703	isobutyryl-CoA mutase activity
CNX65_RS11585	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNX65_RS11585	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CNX65_RS11600	COG0187	DNA topoisomerase II activity
CNX65_RS11630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CNX65_RS11635	COG1716	ATPase activity
CNX65_RS11635	COG5001	Diguanylate cyclase
CNX65_RS11660	COG3845	ABC transporter
CNX65_RS11680	COG2226	methyltransferase
CNX65_RS11690	COG1940	carbohydrate kinase activity
CNX65_RS11695	COG0673	inositol 2-dehydrogenase activity
CNX65_RS11705	COG0277	FAD linked oxidase domain protein
CNX65_RS11755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS11760	COG2205	protein histidine kinase activity
CNX65_RS11775	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CNX65_RS11785	COG0745	RESPONSE REGULATOR receiver
CNX65_RS11795	COG0745	RESPONSE REGULATOR receiver
CNX65_RS11805	COG2201	protein-glutamate methylesterase activity
CNX65_RS11820	COG0835	chemotaxis
CNX65_RS11825	COG0643	Histidine kinase
CNX65_RS11825	COG0784	Response regulator, receiver
CNX65_RS11825	COG2198	Histidine kinase
CNX65_RS11855	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CNX65_RS11865	COG1987	bacterial-type flagellum assembly
CNX65_RS11870	COG1338	Plays a role in the flagellum-specific transport system
CNX65_RS11900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CNX65_RS11910	COG4786	Flagellar basal body rod
CNX65_RS11925	COG0741	lytic transglycosylase activity
CNX65_RS11945	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CNX65_RS11950	COG1766	The M ring may be actively involved in energy transduction
CNX65_RS11955	COG1677	Flagellar hook-basal body complex protein FliE
CNX65_RS11975	COG1516	flagellar protein fliS
CNX65_RS11990	COG1191	sigma factor activity
CNX65_RS12000	COG1256	bacterial-type flagellum assembly
CNX65_RS12000	COG4786	Flagellar basal body rod
CNX65_RS12010	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CNX65_RS12015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CNX65_RS12045	COG5002	protein histidine kinase activity
CNX65_RS12050	COG3852	Histidine kinase
CNX65_RS12055	COG0745	RESPONSE REGULATOR receiver
CNX65_RS12055	COG2205	protein histidine kinase activity
CNX65_RS12055	COG4191	Histidine kinase
CNX65_RS12065	COG2204	response regulator
CNX65_RS12095	COG1846	Transcriptional regulator
CNX65_RS12115	COG4251	negative regulation of phosphorylation
CNX65_RS12130	COG1522	sequence-specific DNA binding
CNX65_RS12135	COG2814	Major facilitator Superfamily
CNX65_RS12165	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS12175	COG0326	Molecular chaperone. Has ATPase activity
CNX65_RS12225	COG1609	Transcriptional regulator
CNX65_RS12235	COG1175	transmembrane transport
CNX65_RS12240	COG0395	ABC-type sugar transport system, permease component
CNX65_RS12280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CNX65_RS12310	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS12335	COG0277	FAD linked oxidase domain protein
CNX65_RS12380	COG0420	3'-5' exonuclease activity
CNX65_RS12405	COG0604	alcohol dehydrogenase
CNX65_RS12405	COG3321	synthase
CNX65_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS12425	COG2119	membrane
CNX65_RS12460	COG0747	negative chemotaxis
CNX65_RS12470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_RS12490	COG0745	RESPONSE REGULATOR receiver
CNX65_RS12495	COG2205	protein histidine kinase activity
CNX65_RS12515	COG1802	Transcriptional regulator
CNX65_RS12555	COG1335	isochorismatase
CNX65_RS12645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNX65_RS12655	COG1819	glycosyl
CNX65_RS12660	COG1132	(ABC) transporter
CNX65_RS12690	COG3795	YCII-related domain
CNX65_RS12695	COG4941	Belongs to the sigma-70 factor family
CNX65_RS12740	COG0714	Associated with various cellular activities
CNX65_RS12745	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CNX65_RS12805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CNX65_RS12815	COG0515	serine threonine protein kinase
CNX65_RS12835	COG2124	cytochrome p450
CNX65_RS12845	COG2814	Major facilitator Superfamily
CNX65_RS12855	COG4581	dead DEAH box helicase
CNX65_RS12895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNX65_RS12910	COG0477	Major facilitator Superfamily
CNX65_RS12920	COG1612	heme a metabolic process
CNX65_RS12935	COG5001	Diguanylate cyclase
CNX65_RS12975	COG2205	protein histidine kinase activity
CNX65_RS12980	COG0745	RESPONSE REGULATOR receiver
CNX65_RS13010	COG2423	ornithine cyclodeaminase activity
CNX65_RS13055	COG0395	ABC-type sugar transport system, permease component
CNX65_RS13075	COG1609	Transcriptional regulator
CNX65_RS13090	COG1595	DNA-templated transcription, initiation
CNX65_RS13175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CNX65_RS13180	COG0477	Major facilitator Superfamily
CNX65_RS13225	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS13230	COG1309	transcriptional regulator
CNX65_RS13235	COG3384	dioxygenase
CNX65_RS13240	COG0702	epimerase
CNX65_RS13270	COG0488	(ABC) transporter
CNX65_RS13280	COG0640	Transcriptional regulator
CNX65_RS13285	COG0346	lactoylglutathione lyase activity
CNX65_RS13305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS13315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS13325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_RS13345	COG2205	protein histidine kinase activity
CNX65_RS13355	COG1253	flavin adenine dinucleotide binding
CNX65_RS13365	COG0604	alcohol dehydrogenase
CNX65_RS13375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CNX65_RS13375	COG2080	2 iron, 2 sulfur cluster binding
CNX65_RS13415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_RS13425	COG2376	Dihydroxyacetone kinase
CNX65_RS13430	COG0698	ribose 5-phosphate isomerase
CNX65_RS13435	COG0149	triose-phosphate isomerase activity
CNX65_RS13440	COG1082	Xylose isomerase domain protein TIM barrel
CNX65_RS13445	COG2084	Dehydrogenase
CNX65_RS13485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_RS13485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_RS13495	COG1834	amidinotransferase
CNX65_RS13510	COG0475	glutathione-regulated potassium exporter activity
CNX65_RS13515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CNX65_RS13550	COG1131	(ABC) transporter
CNX65_RS13570	COG0477	Major facilitator Superfamily
CNX65_RS13590	COG0604	alcohol dehydrogenase
CNX65_RS13590	COG3321	synthase
CNX65_RS13595	COG2267	carboxylic ester hydrolase activity
CNX65_RS13610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS13625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX65_RS13630	COG1509	lysine 2,3-aminomutase activity
CNX65_RS13655	COG1136	(ABC) transporter
CNX65_RS13690	COG4122	O-methyltransferase activity
CNX65_RS13705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS13710	COG1120	ATPase activity
CNX65_RS13770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CNX65_RS13785	COG1120	ATPase activity
CNX65_RS13790	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS13795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS13800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CNX65_RS13805	COG2375	cellular response to nickel ion
CNX65_RS13810	COG1535	isochorismatase
CNX65_RS13810	COG3433	isochorismatase activity
CNX65_RS13815	COG3433	isochorismatase activity
CNX65_RS13815	COG1535	isochorismatase
CNX65_RS13820	COG1021	2,3-dihydroxybenzoate-AMP ligase
CNX65_RS13825	COG1169	isochorismate synthase
CNX65_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS13850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS13855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CNX65_RS13870	COG3655	Transcriptional regulator
CNX65_RS13885	COG4585	Histidine kinase
CNX65_RS13890	COG2197	response regulator
CNX65_RS13900	COG0148	phosphopyruvate hydratase activity
CNX65_RS13915	COG4152	abc transporter atp-binding protein
CNX65_RS13920	COG1668	transmembrane transport
CNX65_RS13960	COG0477	Major facilitator Superfamily
CNX65_RS13970	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CNX65_RS13975	COG2197	response regulator
CNX65_RS13985	COG0577	efflux transmembrane transporter activity
CNX65_RS13985	COG1136	(ABC) transporter
CNX65_RS14045	COG1309	transcriptional regulator
CNX65_RS14050	COG1132	(ABC) transporter
CNX65_RS14065	COG0738	Major facilitator superfamily
CNX65_RS14080	COG0583	DNA-binding transcription factor activity
CNX65_RS14085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_RS14095	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS14115	COG2409	Drug exporters of the RND superfamily
CNX65_RS14125	COG2027	D-alanyl-D-alanine carboxypeptidase
CNX65_RS14135	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS14205	COG2226	methyltransferase
CNX65_RS14230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CNX65_RS14235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CNX65_RS14250	COG1131	(ABC) transporter
CNX65_RS14260	COG3321	synthase
CNX65_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS14260	COG0604	alcohol dehydrogenase
CNX65_RS14290	COG1653	transport
CNX65_RS14300	COG3833	ABC-type maltose transport systems, permease component
CNX65_RS14315	COG3507	Belongs to the glycosyl hydrolase 43 family
CNX65_RS14325	COG0596	Alpha beta hydrolase
CNX65_RS14340	COG2197	response regulator
CNX65_RS14360	COG0028	Belongs to the TPP enzyme family
CNX65_RS14365	COG1473	amidohydrolase
CNX65_RS14370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS14385	COG1177	transmembrane transport
CNX65_RS14390	COG1176	ABC-type spermidine putrescine transport system, permease component I
CNX65_RS14395	COG3842	ATPase activity
CNX65_RS14405	COG4221	oxidoreductase activity
CNX65_RS14425	COG1309	transcriptional regulator
CNX65_RS14470	COG3209	COG3209 Rhs family protein
CNX65_RS14520	COG0135	phosphoribosylanthranilate isomerase activity
CNX65_RS14560	COG3629	intracellular signal transduction
CNX65_RS14560	COG3903	Transcriptional regulator
CNX65_RS14575	COG2076	Multidrug Resistance protein
CNX65_RS14620	COG0642	Histidine kinase
CNX65_RS14635	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_RS14665	COG3831	ATPase activity
CNX65_RS14670	COG4251	negative regulation of phosphorylation
CNX65_RS14680	COG0784	Response regulator, receiver
CNX65_RS14700	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS14710	COG0395	ABC-type sugar transport system, permease component
CNX65_RS14730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNX65_RS14745	COG3629	intracellular signal transduction
CNX65_RS14745	COG3903	Transcriptional regulator
CNX65_RS14785	COG1222	aaa ATPase
CNX65_RS14875	COG3903	Transcriptional regulator
CNX65_RS14875	COG3629	intracellular signal transduction
CNX65_RS14920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNX65_RS14930	COG3831	ATPase activity
CNX65_RS14935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CNX65_RS14970	COG0673	inositol 2-dehydrogenase activity
CNX65_RS14985	COG0494	nUDIX hydrolase
CNX65_RS15020	COG2182	Extracellular solute-binding protein
CNX65_RS15030	COG0395	ABC-type sugar transport system, permease component
CNX65_RS15035	COG1501	Belongs to the glycosyl hydrolase 31 family
CNX65_RS15045	COG1609	Transcriptional regulator
CNX65_RS15080	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_RS15100	COG2318	DinB family
CNX65_RS15115	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS15125	COG0789	Transcriptional regulator
CNX65_RS15130	COG2197	response regulator
CNX65_RS15135	COG4585	Histidine kinase
CNX65_RS15140	COG0577	efflux transmembrane transporter activity
CNX65_RS15140	COG1136	(ABC) transporter
CNX65_RS15160	COG0366	Alpha amylase catalytic
CNX65_RS15195	COG2375	cellular response to nickel ion
CNX65_RS15200	COG3903	Transcriptional regulator
CNX65_RS15200	COG3629	intracellular signal transduction
CNX65_RS15225	COG3831	ATPase activity
CNX65_RS15260	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_RS15270	COG1132	(ABC) transporter
CNX65_RS15310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS15315	COG0300	oxidoreductase activity
CNX65_RS15330	COG0604	alcohol dehydrogenase
CNX65_RS15330	COG3321	synthase
CNX65_RS15345	COG0604	alcohol dehydrogenase
CNX65_RS15345	COG3321	synthase
CNX65_RS15375	COG3973	AAA domain
CNX65_RS15410	COG1556	Lactate utilization protein
CNX65_RS15415	COG1139	Iron-sulfur cluster binding protein
CNX65_RS15420	COG0247	lactate metabolic process
CNX65_RS15425	COG2188	Transcriptional regulator
CNX65_RS15430	COG1609	Transcriptional regulator
CNX65_RS15435	COG1129	ABC transporter
CNX65_RS15445	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_RS15460	COG3347	Dehydrogenase
CNX65_RS15460	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS15465	COG1070	Carbohydrate kinase
CNX65_RS15475	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_RS15490	COG0586	Pfam SNARE associated Golgi protein
CNX65_RS15495	COG4585	Histidine kinase
CNX65_RS15500	COG2197	response regulator
CNX65_RS15505	COG3851	Histidine kinase
CNX65_RS15555	COG5398	heme oxygenase
CNX65_RS15580	COG0601	transmembrane transport
CNX65_RS15585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_RS15590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNX65_RS15595	COG1136	(ABC) transporter
CNX65_RS15600	COG0367	asparagine synthase
CNX65_RS15620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CNX65_RS15625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CNX65_RS15630	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS15680	COG0583	DNA-binding transcription factor activity
CNX65_RS15715	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CNX65_RS15720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNX65_RS15735	COG3345	alpha-galactosidase
CNX65_RS15750	COG0644	oxidoreductase
CNX65_RS15755	COG0156	8-amino-7-oxononanoate synthase activity
CNX65_RS15775	COG3903	Transcriptional regulator
CNX65_RS15775	COG3629	intracellular signal transduction
CNX65_RS15785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_RS15790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS15820	COG0583	DNA-binding transcription factor activity
CNX65_RS15835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_RS15850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNX65_RS15855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CNX65_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS15870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_RS15875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNX65_RS15900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CNX65_RS15905	COG0235	Class ii aldolase
CNX65_RS15910	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS15915	COG0477	Major facilitator Superfamily
CNX65_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS15995	COG1063	alcohol dehydrogenase
CNX65_RS16005	COG0659	secondary active sulfate transmembrane transporter activity
CNX65_RS16030	COG1408	metallophosphoesterase
CNX65_RS16050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNX65_RS16050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CNX65_RS16055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNX65_RS16065	COG2409	Drug exporters of the RND superfamily
CNX65_RS16080	COG1024	Enoyl-CoA hydratase
CNX65_RS16120	COG1132	(ABC) transporter
CNX65_RS16125	COG0475	glutathione-regulated potassium exporter activity
CNX65_RS16185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_RS16200	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_RS16205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNX65_RS16235	COG3795	YCII-related domain
CNX65_RS16255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CNX65_RS16265	COG3321	synthase
CNX65_RS16265	COG0604	alcohol dehydrogenase
CNX65_RS16310	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS16325	COG2124	cytochrome p450
CNX65_RS16325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CNX65_RS16375	COG3507	Belongs to the glycosyl hydrolase 43 family
CNX65_RS16410	COG4585	Histidine kinase
CNX65_RS16415	COG2197	response regulator
CNX65_RS16445	COG4221	oxidoreductase activity
CNX65_RS16450	COG0667	Aldo Keto reductase
CNX65_RS16470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CNX65_RS16475	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CNX65_RS16525	COG0546	phosphoglycolate phosphatase activity
CNX65_RS16560	COG3693	PFAM glycoside hydrolase, family 10
CNX65_RS16560	COG3509	depolymerase
CNX65_RS16565	COG3507	Belongs to the glycosyl hydrolase 43 family
CNX65_RS16575	COG1609	Transcriptional regulator
CNX65_RS16590	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS16620	COG1073	alpha beta
CNX65_RS16635	COG0714	Associated with various cellular activities
CNX65_RS16730	COG3507	Belongs to the glycosyl hydrolase 43 family
CNX65_RS16745	COG1609	Transcriptional regulator
CNX65_RS16755	COG1733	regulation of RNA biosynthetic process
CNX65_RS16775	COG0596	Alpha beta hydrolase
CNX65_RS16785	COG0596	Alpha beta hydrolase
CNX65_RS16815	COG2261	transglycosylase associated protein
CNX65_RS16825	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CNX65_RS16845	COG2197	response regulator
CNX65_RS16860	COG1064	alcohol dehydrogenase
CNX65_RS16865	COG1309	transcriptional regulator
CNX65_RS16875	COG1454	alcohol dehydrogenase
CNX65_RS16880	COG0126	phosphoglycerate kinase activity
CNX65_RS16885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CNX65_RS16890	COG1063	alcohol dehydrogenase
CNX65_RS16895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNX65_RS16900	COG0259	pyridoxamine-phosphate oxidase activity
CNX65_RS16905	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CNX65_RS16920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS16930	COG0477	Major facilitator Superfamily
CNX65_RS16940	COG1063	alcohol dehydrogenase
CNX65_RS16945	COG0667	Aldo Keto reductase
CNX65_RS16960	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CNX65_RS16965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CNX65_RS16975	COG0494	nUDIX hydrolase
CNX65_RS16980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CNX65_RS16990	COG1335	isochorismatase
CNX65_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS17025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS17025	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS17025	COG0300	oxidoreductase activity
CNX65_RS17025	COG3321	synthase
CNX65_RS17055	COG1132	(ABC) transporter
CNX65_RS17060	COG1132	(ABC) transporter
CNX65_RS17070	COG1725	Transcriptional regulator
CNX65_RS17105	COG0028	Belongs to the TPP enzyme family
CNX65_RS17135	COG3629	intracellular signal transduction
CNX65_RS17135	COG3903	Transcriptional regulator
CNX65_RS17170	COG2249	NAD(P)H dehydrogenase (quinone) activity
CNX65_RS17190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CNX65_RS17195	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CNX65_RS17205	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CNX65_RS17220	COG1607	acyl-coa hydrolase
CNX65_RS17240	COG0463	Glycosyl transferase, family 2
CNX65_RS17265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNX65_RS17275	COG1435	thymidine kinase activity
CNX65_RS17305	COG3706	GGDEF domain
CNX65_RS17315	COG3467	pyridoxamine 5'-phosphate
CNX65_RS17325	COG2161	toxin-antitoxin pair type II binding
CNX65_RS17330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CNX65_RS17355	COG2226	methyltransferase
CNX65_RS17360	COG0640	Transcriptional regulator
CNX65_RS17365	COG0798	PFAM Bile acid sodium symporter
CNX65_RS17370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNX65_RS17380	COG0604	alcohol dehydrogenase
CNX65_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS17455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_RS17460	COG1349	DNA-binding transcription factor activity
CNX65_RS17465	COG0494	nUDIX hydrolase
CNX65_RS17475	COG2176	DNA-directed DNA polymerase activity
CNX65_RS17475	COG5002	protein histidine kinase activity
CNX65_RS17525	COG1619	proteins homologs of microcin C7 resistance protein MccF
CNX65_RS17555	COG1011	Hydrolase
CNX65_RS17565	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS17590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_RS17595	COG0601	transmembrane transport
CNX65_RS17600	COG0747	negative chemotaxis
CNX65_RS17610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_RS17625	COG1609	Transcriptional regulator
CNX65_RS17645	COG4974	Belongs to the 'phage' integrase family
CNX65_RS17670	COG0667	Aldo Keto reductase
CNX65_RS17685	COG1309	transcriptional regulator
CNX65_RS17720	COG2755	lipolytic protein G-D-S-L family
CNX65_RS17755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CNX65_RS17770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CNX65_RS17780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_RS17795	COG1846	Transcriptional regulator
CNX65_RS17825	COG1643	Atp-dependent helicase
CNX65_RS17845	COG1968	undecaprenyl-diphosphatase activity
CNX65_RS17850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS17855	COG0667	Aldo Keto reductase
CNX65_RS17900	COG2909	trisaccharide binding
CNX65_RS17905	COG1414	Transcriptional regulator
CNX65_RS17915	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CNX65_RS17970	COG2814	Major facilitator Superfamily
CNX65_RS18000	COG1216	Glycosyl transferase, family 2
CNX65_RS18000	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS18035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS18050	COG1404	Belongs to the peptidase S8 family
CNX65_RS18055	COG1309	transcriptional regulator
CNX65_RS18060	COG0667	Aldo Keto reductase
CNX65_RS18065	COG4552	Acetyltransferase involved in intracellular survival and related
CNX65_RS18075	COG3629	intracellular signal transduction
CNX65_RS18075	COG3903	Transcriptional regulator
CNX65_RS18090	COG2197	response regulator
CNX65_RS18100	COG2124	cytochrome p450
CNX65_RS18125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS18130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_RS18135	COG0604	alcohol dehydrogenase
CNX65_RS18135	COG3321	synthase
CNX65_RS18135	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS18160	COG0310	cobalt ion transport
CNX65_RS18190	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CNX65_RS18190	COG2508	Transcriptional regulator
CNX65_RS18195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CNX65_RS18200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNX65_RS18215	COG2124	cytochrome p450
CNX65_RS18235	COG1132	(ABC) transporter
CNX65_RS18275	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS18285	COG0431	NADPH-dependent FMN reductase
CNX65_RS18290	COG3629	intracellular signal transduction
CNX65_RS18290	COG3903	Transcriptional regulator
CNX65_RS18300	COG0287	Prephenate dehydrogenase
CNX65_RS18335	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CNX65_RS18340	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS18345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS18355	COG1131	(ABC) transporter
CNX65_RS18365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CNX65_RS18370	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_RS18370	COG0022	dehydrogenase e1 component
CNX65_RS18380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CNX65_RS18395	COG1132	(ABC) transporter
CNX65_RS18400	COG1132	(ABC) transporter
CNX65_RS18410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CNX65_RS18425	COG0110	maltose O-acetyltransferase activity
CNX65_RS18470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNX65_RS18505	COG1132	(ABC) transporter
CNX65_RS18535	COG1309	transcriptional regulator
CNX65_RS18560	COG3290	protein histidine kinase activity
CNX65_RS18565	COG4565	transcriptional regulatory protein
CNX65_RS18575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS18580	COG1309	transcriptional regulator
CNX65_RS18675	COG3395	kinase activity
CNX65_RS18680	COG0235	Class ii aldolase
CNX65_RS18685	COG1349	DNA-binding transcription factor activity
CNX65_RS18700	COG0387	Pfam Sodium calcium exchanger
CNX65_RS18720	COG2205	protein histidine kinase activity
CNX65_RS18720	COG2198	Histidine kinase
CNX65_RS18720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_RS18720	COG0784	Response regulator, receiver
CNX65_RS18730	COG2172	sigma factor antagonist activity
CNX65_RS18735	COG1366	Belongs to the anti-sigma-factor antagonist family
CNX65_RS18740	COG1366	Belongs to the anti-sigma-factor antagonist family
CNX65_RS18755	COG2072	flavoprotein involved in K transport
CNX65_RS18825	COG3537	Alpha-1,2-mannosidase
CNX65_RS18840	COG0789	Transcriptional regulator
CNX65_RS18865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_RS18950	COG4257	antibiotic catabolic process
CNX65_RS18975	COG3345	alpha-galactosidase
CNX65_RS19000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNX65_RS19005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_RS19025	COG1959	2 iron, 2 sulfur cluster binding
CNX65_RS19030	COG1017	nitric oxide dioxygenase activity
CNX65_RS19030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CNX65_RS19055	COG0142	geranyltranstransferase activity
CNX65_RS19075	COG4106	trans-aconitate 2-methyltransferase activity
CNX65_RS19100	COG0667	Aldo Keto reductase
CNX65_RS19140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CNX65_RS19190	COG0604	alcohol dehydrogenase
CNX65_RS19210	COG3537	Alpha-1,2-mannosidase
CNX65_RS19215	COG0596	Alpha beta hydrolase
CNX65_RS19240	COG2814	Major facilitator Superfamily
CNX65_RS19250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CNX65_RS19310	COG2755	lipolytic protein G-D-S-L family
CNX65_RS19320	COG0745	RESPONSE REGULATOR receiver
CNX65_RS19335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CNX65_RS19370	COG5520	Belongs to the glycosyl hydrolase 30 family
CNX65_RS19385	COG0840	transmembrane signaling receptor activity
CNX65_RS19415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNX65_RS19420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNX65_RS19430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNX65_RS19435	COG0798	PFAM Bile acid sodium symporter
CNX65_RS19445	COG2072	flavoprotein involved in K transport
CNX65_RS19455	COG0456	acetyltransferase
CNX65_RS19480	COG2910	NAD(P)H-binding
CNX65_RS19515	COG0477	Major facilitator Superfamily
CNX65_RS19525	COG2072	flavoprotein involved in K transport
CNX65_RS19535	COG0657	acetylesterase activity
CNX65_RS19645	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CNX65_RS19655	COG1120	ATPase activity
CNX65_RS19660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS19695	COG3940	Belongs to the glycosyl hydrolase 43 family
CNX65_RS19760	COG1309	transcriptional regulator
CNX65_RS19805	COG3509	depolymerase
CNX65_RS19835	COG1064	alcohol dehydrogenase
CNX65_RS19895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNX65_RS19900	COG1309	transcriptional regulator
CNX65_RS19905	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS19920	COG3226	Transcriptional regulator
CNX65_RS19925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX65_RS19940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS19970	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS19975	COG0435	Glutathione S-transferase
CNX65_RS20000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CNX65_RS20020	COG3851	Histidine kinase
CNX65_RS20025	COG2197	response regulator
CNX65_RS20065	COG0673	inositol 2-dehydrogenase activity
CNX65_RS20095	COG0745	RESPONSE REGULATOR receiver
CNX65_RS20100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CNX65_RS20130	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_RS20165	COG0515	serine threonine protein kinase
CNX65_RS20190	COG0492	ferredoxin-NADP+ reductase activity
CNX65_RS20205	COG0475	glutathione-regulated potassium exporter activity
CNX65_RS20215	COG5002	protein histidine kinase activity
CNX65_RS20215	COG5000	phosphorelay sensor kinase activity
CNX65_RS20260	COG1136	(ABC) transporter
CNX65_RS20260	COG0577	efflux transmembrane transporter activity
CNX65_RS20275	COG2197	response regulator
CNX65_RS20280	COG3851	Histidine kinase
CNX65_RS20345	COG1309	transcriptional regulator
CNX65_RS20355	COG2814	Major facilitator Superfamily
CNX65_RS20365	COG5002	protein histidine kinase activity
CNX65_RS20370	COG0745	RESPONSE REGULATOR receiver
CNX65_RS20380	COG1136	(ABC) transporter
CNX65_RS20380	COG0577	efflux transmembrane transporter activity
CNX65_RS20385	COG0577	efflux transmembrane transporter activity
CNX65_RS20415	COG2345	Transcriptional regulator
CNX65_RS20450	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS20460	COG2814	Major facilitator Superfamily
CNX65_RS20490	COG0596	Alpha beta hydrolase
CNX65_RS20515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CNX65_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS20540	COG2124	cytochrome p450
CNX65_RS20600	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS20605	COG1024	Enoyl-CoA hydratase
CNX65_RS20620	COG1917	Cupin 2, conserved barrel domain protein
CNX65_RS20620	COG4977	sequence-specific DNA binding
CNX65_RS20635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_RS20670	COG1609	Transcriptional regulator
CNX65_RS20680	COG4948	Mandelate Racemase Muconate Lactonizing
CNX65_RS20745	COG2267	carboxylic ester hydrolase activity
CNX65_RS20810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNX65_RS20820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CNX65_RS20840	COG1414	Transcriptional regulator
CNX65_RS20845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CNX65_RS20850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNX65_RS20890	COG3340	Belongs to the peptidase S51 family
CNX65_RS20915	COG0604	alcohol dehydrogenase
CNX65_RS20915	COG3321	synthase
CNX65_RS20930	COG0024	Methionine aminopeptidase
CNX65_RS20935	COG3903	Transcriptional regulator
CNX65_RS20935	COG3629	intracellular signal transduction
CNX65_RS20950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CNX65_RS20960	COG4221	oxidoreductase activity
CNX65_RS20995	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CNX65_RS21000	COG1404	Belongs to the peptidase S8 family
CNX65_RS21005	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CNX65_RS21005	COG4932	domain protein
CNX65_RS21005	COG3266	domain, Protein
CNX65_RS21030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_RS21035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CNX65_RS21045	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CNX65_RS21055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_RS21055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_RS21065	COG0697	spore germination
CNX65_RS21070	COG0644	oxidoreductase
CNX65_RS21080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS21110	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_RS21145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CNX65_RS21160	COG0659	secondary active sulfate transmembrane transporter activity
CNX65_RS21175	COG2255	four-way junction helicase activity
CNX65_RS21210	COG3467	pyridoxamine 5'-phosphate
CNX65_RS21215	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_RS21220	COG2124	cytochrome p450
CNX65_RS21225	COG0514	ATP-dependent DNA helicase (RecQ)
CNX65_RS21230	COG0726	polysaccharide deacetylase
CNX65_RS21235	COG0439	Biotin carboxylase
CNX65_RS21240	COG0395	ABC-type sugar transport system, permease component
CNX65_RS21245	COG1175	transmembrane transport
CNX65_RS21250	COG2182	Extracellular solute-binding protein
CNX65_RS21260	COG0667	Aldo Keto reductase
CNX65_RS21280	COG0300	oxidoreductase activity
CNX65_RS21320	COG0110	maltose O-acetyltransferase activity
CNX65_RS21325	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNX65_RS21340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CNX65_RS21345	COG2197	response regulator
CNX65_RS21350	COG3850	Histidine kinase
CNX65_RS21365	COG1695	Transcriptional regulator
CNX65_RS21370	COG3831	ATPase activity
CNX65_RS21430	COG0534	Mate efflux family protein
CNX65_RS21445	COG0640	Transcriptional regulator
CNX65_RS21460	COG0640	Transcriptional regulator
CNX65_RS21465	COG0672	)-iron permease
CNX65_RS21475	COG2837	iron assimilation
CNX65_RS21495	COG0596	Alpha beta hydrolase
CNX65_RS21500	COG1120	ATPase activity
CNX65_RS21505	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS21510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS21535	COG1982	Orn Lys Arg decarboxylase major
CNX65_RS21565	COG0277	FAD linked oxidase domain protein
CNX65_RS21585	COG0583	DNA-binding transcription factor activity
CNX65_RS21590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS21595	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS21645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNX65_RS21650	COG4172	Belongs to the ABC transporter superfamily
CNX65_RS21695	COG0784	Response regulator, receiver
CNX65_RS21710	COG1522	sequence-specific DNA binding
CNX65_RS21720	COG0861	Integral membrane protein TerC family
CNX65_RS21725	COG1309	transcriptional regulator
CNX65_RS21735	COG2807	transmembrane transport
CNX65_RS21760	COG2814	Major facilitator Superfamily
CNX65_RS21790	COG2986	histidine ammonia-lyase
CNX65_RS21800	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS21815	COG3321	synthase
CNX65_RS21815	COG0604	alcohol dehydrogenase
CNX65_RS21835	COG1819	glycosyl
CNX65_RS21855	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS21870	COG0183	Belongs to the thiolase family
CNX65_RS21875	COG1024	Enoyl-CoA hydratase
CNX65_RS21875	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_RS21905	COG1201	RNA secondary structure unwinding
CNX65_RS21920	COG0556	nucleotide-excision repair
CNX65_RS21935	COG0142	geranyltranstransferase activity
CNX65_RS21940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CNX65_RS21945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CNX65_RS21955	COG2175	clavaminate synthase activity
CNX65_RS21970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX65_RS21995	COG2340	Cysteine-rich secretory protein family
CNX65_RS22010	COG1309	transcriptional regulator
CNX65_RS22025	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS22030	COG1309	transcriptional regulator
CNX65_RS22035	COG0789	Transcriptional regulator
CNX65_RS22050	COG1132	(ABC) transporter
CNX65_RS22055	COG1132	(ABC) transporter
CNX65_RS22060	COG3831	ATPase activity
CNX65_RS22075	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS22105	COG0254	rRNA binding
CNX65_RS22115	COG0753	catalase activity
CNX65_RS22120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNX65_RS22120	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_RS22125	COG2258	MOSC domain
CNX65_RS22145	COG0604	alcohol dehydrogenase
CNX65_RS22155	COG0604	alcohol dehydrogenase
CNX65_RS22175	COG0583	DNA-binding transcription factor activity
CNX65_RS22190	COG0730	response to heat
CNX65_RS22205	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS22230	COG3903	Transcriptional regulator
CNX65_RS22230	COG3629	intracellular signal transduction
CNX65_RS22250	COG1022	Amp-dependent synthetase and ligase
CNX65_RS22265	COG1309	transcriptional regulator
CNX65_RS22270	COG0778	Nitroreductase
CNX65_RS22300	COG1063	alcohol dehydrogenase
CNX65_RS22325	COG1509	lysine 2,3-aminomutase activity
CNX65_RS22335	COG0644	oxidoreductase
CNX65_RS22340	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CNX65_RS22345	COG2808	Putative FMN-binding domain
CNX65_RS22395	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CNX65_RS22400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CNX65_RS22435	COG3973	AAA domain
CNX65_RS22450	COG2205	protein histidine kinase activity
CNX65_RS22455	COG0745	RESPONSE REGULATOR receiver
CNX65_RS22550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CNX65_RS22595	COG1674	ftsk spoiiie
CNX65_RS22755	COG1088	dTDP-glucose 4,6-dehydratase activity
CNX65_RS22765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_RS22770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_RS22775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNX65_RS22780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CNX65_RS22795	COG1132	(ABC) transporter
CNX65_RS22800	COG1132	(ABC) transporter
CNX65_RS22825	COG1404	Belongs to the peptidase S8 family
CNX65_RS22850	COG0561	phosphatase activity
CNX65_RS22885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CNX65_RS22890	COG3845	ABC transporter
CNX65_RS22895	COG1122	ATPase activity
CNX65_RS22910	COG1609	Transcriptional regulator
CNX65_RS22920	COG1175	transmembrane transport
CNX65_RS22925	COG0395	ABC-type sugar transport system, permease component
CNX65_RS22930	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_RS22975	COG1302	Protein conserved in bacteria
CNX65_RS23010	COG3321	synthase
CNX65_RS23010	COG0604	alcohol dehydrogenase
CNX65_RS23045	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS23060	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS23090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_RS23105	COG0583	DNA-binding transcription factor activity
CNX65_RS23110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNX65_RS23115	COG3250	beta-galactosidase activity
CNX65_RS23125	COG4566	intracellular signal transduction
CNX65_RS23130	COG3321	synthase
CNX65_RS23130	COG0604	alcohol dehydrogenase
CNX65_RS23130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CNX65_RS23130	COG4221	oxidoreductase activity
CNX65_RS23200	COG1022	Amp-dependent synthetase and ligase
CNX65_RS23210	COG0657	acetylesterase activity
CNX65_RS23215	COG0022	dehydrogenase e1 component
CNX65_RS23215	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_RS23220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNX65_RS23240	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS23265	COG2755	lipolytic protein G-D-S-L family
CNX65_RS23290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS23300	COG2755	lipolytic protein G-D-S-L family
CNX65_RS23325	COG1309	transcriptional regulator
CNX65_RS23330	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS23335	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS23390	COG3321	synthase
CNX65_RS23390	COG0604	alcohol dehydrogenase
CNX65_RS23410	COG0702	epimerase
CNX65_RS23425	COG1733	regulation of RNA biosynthetic process
CNX65_RS23460	COG0006	proline dipeptidase activity
CNX65_RS23475	COG0444	Belongs to the ABC transporter superfamily
CNX65_RS23490	COG0747	negative chemotaxis
CNX65_RS23495	COG1802	Transcriptional regulator
CNX65_RS23505	COG3938	Belongs to the proline racemase family
CNX65_RS23510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNX65_RS23525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CNX65_RS23530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CNX65_RS23535	COG1609	Transcriptional regulator
CNX65_RS23545	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_RS23575	COG1131	(ABC) transporter
CNX65_RS23585	COG1595	DNA-templated transcription, initiation
CNX65_RS23650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNX65_RS23685	COG1121	(ABC) transporter
CNX65_RS23690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CNX65_RS23700	COG0523	cobalamin synthesis protein
CNX65_RS23750	COG1120	ATPase activity
CNX65_RS23755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS23795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_RS23815	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS23825	COG1309	transcriptional regulator
CNX65_RS23830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_RS23835	COG2391	methyltransferase activity
CNX65_RS23855	COG0477	Major facilitator Superfamily
CNX65_RS23915	COG2018	Roadblock/LC7 domain
CNX65_RS23930	COG0673	inositol 2-dehydrogenase activity
CNX65_RS23945	COG1929	Belongs to the glycerate kinase type-1 family
CNX65_RS23965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CNX65_RS24005	COG2124	cytochrome p450
CNX65_RS24015	COG1216	Glycosyl transferase, family 2
CNX65_RS24025	COG0702	epimerase
CNX65_RS24045	COG3386	PFAM SMP-30 Gluconolaconase
CNX65_RS24050	COG2072	flavoprotein involved in K transport
CNX65_RS24090	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_RS24100	COG0456	acetyltransferase
CNX65_RS24120	COG1414	Transcriptional regulator
CNX65_RS24135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_RS24145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_RS24160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNX65_RS24170	COG0583	DNA-binding transcription factor activity
CNX65_RS24185	COG1902	pentaerythritol trinitrate reductase activity
CNX65_RS24215	COG1802	Transcriptional regulator
CNX65_RS24225	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS24230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS24255	COG2208	phosphoserine phosphatase activity
CNX65_RS24255	COG2770	Histidine kinase
CNX65_RS24265	COG2365	Tyrosine phosphatase family
CNX65_RS24275	COG2755	lipolytic protein G-D-S-L family
CNX65_RS24280	COG3835	regulator
CNX65_RS24290	COG0601	transmembrane transport
CNX65_RS24315	COG1929	Belongs to the glycerate kinase type-1 family
CNX65_RS24325	COG2205	protein histidine kinase activity
CNX65_RS24330	COG0745	RESPONSE REGULATOR receiver
CNX65_RS24355	COG0583	DNA-binding transcription factor activity
CNX65_RS24390	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CNX65_RS24435	COG0463	Glycosyl transferase, family 2
CNX65_RS24445	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS24470	COG1472	Belongs to the glycosyl hydrolase 3 family
CNX65_RS24485	COG2267	carboxylic ester hydrolase activity
CNX65_RS24490	COG3693	PFAM glycoside hydrolase, family 10
CNX65_RS24500	COG0500	methyltransferase
CNX65_RS24510	COG2409	Drug exporters of the RND superfamily
CNX65_RS24530	COG1253	flavin adenine dinucleotide binding
CNX65_RS24555	COG0009	L-threonylcarbamoyladenylate synthase
CNX65_RS24565	COG5183	chlorophyll binding
CNX65_RS24565	COG2133	pyrroloquinoline quinone binding
CNX65_RS24580	COG0586	Pfam SNARE associated Golgi protein
CNX65_RS24600	COG2197	response regulator
CNX65_RS24640	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS24645	COG1063	alcohol dehydrogenase
CNX65_RS24660	COG2197	response regulator
CNX65_RS24670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNX65_RS24675	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_RS24690	COG1522	sequence-specific DNA binding
CNX65_RS24695	COG2340	Cysteine-rich secretory protein family
CNX65_RS24700	COG2205	protein histidine kinase activity
CNX65_RS24745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_RS24750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_RS24755	COG0142	geranyltranstransferase activity
CNX65_RS24765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNX65_RS24785	COG0463	Glycosyl transferase, family 2
CNX65_RS24790	COG1064	alcohol dehydrogenase
CNX65_RS24795	COG1309	transcriptional regulator
CNX65_RS24805	COG2855	membrane
CNX65_RS24820	COG4251	negative regulation of phosphorylation
CNX65_RS24825	COG0784	Response regulator, receiver
CNX65_RS24860	COG3973	AAA domain
CNX65_RS24880	COG1309	transcriptional regulator
CNX65_RS24885	COG0300	oxidoreductase activity
CNX65_RS24895	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_RS24900	COG3973	AAA domain
CNX65_RS24905	COG1120	ATPase activity
CNX65_RS24910	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS24915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNX65_RS24935	COG4607	ABC-type enterochelin transport system periplasmic component
CNX65_RS24940	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CNX65_RS24945	COG1132	(ABC) transporter
CNX65_RS24950	COG1132	(ABC) transporter
CNX65_RS24955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_RS24965	COG1233	COG1233 Phytoene dehydrogenase and related
CNX65_RS25225	COG0583	DNA-binding transcription factor activity
CNX65_RS25245	COG1414	Transcriptional regulator
CNX65_RS25250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNX65_RS25260	COG3485	protocatechuate 3,4-dioxygenase
CNX65_RS25270	COG3485	protocatechuate 3,4-dioxygenase
CNX65_RS25275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CNX65_RS25280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CNX65_RS25295	COG2770	Histidine kinase
CNX65_RS25295	COG2208	phosphoserine phosphatase activity
CNX65_RS25300	COG0784	Response regulator, receiver
CNX65_RS25300	COG5002	protein histidine kinase activity
CNX65_RS25315	COG0248	Ppx GppA phosphatase
CNX65_RS25340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS25350	COG1609	Transcriptional regulator
CNX65_RS25360	COG0300	oxidoreductase activity
CNX65_RS25365	COG1309	transcriptional regulator
CNX65_RS25430	COG1609	Transcriptional regulator
CNX65_RS25445	COG0739	heme binding
CNX65_RS25450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNX65_RS25455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNX65_RS25465	COG0596	Alpha beta hydrolase
CNX65_RS25480	COG0583	DNA-binding transcription factor activity
CNX65_RS25490	COG1349	DNA-binding transcription factor activity
CNX65_RS25495	COG4821	SIS domain
CNX65_RS25500	COG1132	(ABC) transporter
CNX65_RS25515	COG0488	(ABC) transporter
CNX65_RS25520	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS25555	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CNX65_RS25590	COG3706	GGDEF domain
CNX65_RS25595	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CNX65_RS25605	COG2151	metal-sulfur cluster biosynthetic enzyme
CNX65_RS25610	COG0822	iron-sulfur transferase activity
CNX65_RS25620	COG0396	ATPase activity
CNX65_RS25660	COG1752	Esterase of the alpha-beta hydrolase superfamily
CNX65_RS25665	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS25675	COG1131	(ABC) transporter
CNX65_RS25710	COG1510	regulation of RNA biosynthetic process
CNX65_RS25720	COG2018	Roadblock/LC7 domain
CNX65_RS25725	COG5002	protein histidine kinase activity
CNX65_RS25735	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_RS25790	COG0109	protoheme IX farnesyltransferase activity
CNX65_RS25800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CNX65_RS25805	COG0166	Belongs to the GPI family
CNX65_RS25820	COG0363	glucosamine-6-phosphate deaminase activity
CNX65_RS25825	COG4585	Histidine kinase
CNX65_RS25850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNX65_RS25855	COG0149	triose-phosphate isomerase activity
CNX65_RS25860	COG0126	phosphoglycerate kinase activity
CNX65_RS25865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CNX65_RS25880	COG1481	regulation of sporulation
CNX65_RS25890	COG1660	Displays ATPase and GTPase activities
CNX65_RS25895	COG0322	excinuclease ABC activity
CNX65_RS25950	COG2234	aminopeptidase activity
CNX65_RS25960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CNX65_RS25965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX65_RS25965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CNX65_RS25995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CNX65_RS26000	COG0242	peptide deformylase activity
CNX65_RS26040	COG0405	Gamma-glutamyltransferase
CNX65_RS26055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNX65_RS26065	COG1758	RNA polymerase activity
CNX65_RS26070	COG0194	GDP metabolic process
CNX65_RS26080	COG0284	orotidine-5'-phosphate decarboxylase activity
CNX65_RS26090	COG0505	Belongs to the CarA family
CNX65_RS26105	COG0540	Belongs to the ATCase OTCase family
CNX65_RS26110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CNX65_RS26120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNX65_RS26125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CNX65_RS26130	COG0006	proline dipeptidase activity
CNX65_RS26140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CNX65_RS26145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CNX65_RS26150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CNX65_RS26155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CNX65_RS26165	COG2190	(PTS) system
CNX65_RS26170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNX65_RS26175	COG2188	Transcriptional regulator
CNX65_RS26180	COG1263	PTS System
CNX65_RS26185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNX65_RS26190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CNX65_RS26200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CNX65_RS26205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CNX65_RS26245	COG4581	dead DEAH box helicase
CNX65_RS26255	COG1388	LysM domain
CNX65_RS26265	COG3279	Response regulator of the LytR AlgR family
CNX65_RS26275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNX65_RS26280	COG3275	phosphorelay sensor kinase activity
CNX65_RS26290	COG0237	dephospho-CoA kinase activity
CNX65_RS26310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CNX65_RS26355	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CNX65_RS26370	COG0604	alcohol dehydrogenase
CNX65_RS26420	COG0395	ABC-type sugar transport system, permease component
CNX65_RS26465	COG2258	MOSC domain
CNX65_RS26470	COG0667	Aldo Keto reductase
CNX65_RS26490	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS26490	COG2030	dehydratase
CNX65_RS26510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNX65_RS26510	COG2755	lipolytic protein G-D-S-L family
CNX65_RS26520	COG1132	(ABC) transporter
CNX65_RS26545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNX65_RS26550	COG0564	pseudouridine synthase activity
CNX65_RS26600	COG1609	Transcriptional regulator
CNX65_RS26650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNX65_RS26650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CNX65_RS26670	COG1716	ATPase activity
CNX65_RS26720	COG0667	Aldo Keto reductase
CNX65_RS26760	COG4585	Histidine kinase
CNX65_RS26765	COG2197	response regulator
CNX65_RS26770	COG2197	response regulator
CNX65_RS26855	COG1222	aaa ATPase
CNX65_RS26895	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CNX65_RS26900	COG1366	Belongs to the anti-sigma-factor antagonist family
CNX65_RS26970	COG2018	Roadblock/LC7 domain
CNX65_RS26980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CNX65_RS26990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CNX65_RS26990	COG1116	anion transmembrane transporter activity
CNX65_RS26995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_RS27000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNX65_RS27010	COG1187	pseudouridine synthase activity
CNX65_RS27015	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CNX65_RS27020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CNX65_RS27035	COG0640	Transcriptional regulator
CNX65_RS27055	COG0494	nUDIX hydrolase
CNX65_RS27060	COG0504	CTP synthase activity
CNX65_RS27090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CNX65_RS27100	COG0647	UMP catabolic process
CNX65_RS27125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CNX65_RS27145	COG2094	Belongs to the DNA glycosylase MPG family
CNX65_RS27150	COG0165	Argininosuccinate lyase
CNX65_RS27155	COG0137	argininosuccinate synthase activity
CNX65_RS27160	COG1438	arginine binding
CNX65_RS27175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CNX65_RS27180	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CNX65_RS27185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CNX65_RS27190	COG0604	alcohol dehydrogenase
CNX65_RS27195	COG1476	TRANSCRIPTIONal
CNX65_RS27215	COG0072	phenylalanine-tRNA ligase activity
CNX65_RS27215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNX65_RS27220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CNX65_RS27225	COG0326	Molecular chaperone. Has ATPase activity
CNX65_RS27235	COG0745	RESPONSE REGULATOR receiver
CNX65_RS27240	COG0642	Histidine kinase
CNX65_RS27245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNX65_RS27250	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CNX65_RS27255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CNX65_RS27260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CNX65_RS27275	COG3629	intracellular signal transduction
CNX65_RS27275	COG3903	Transcriptional regulator
CNX65_RS27300	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CNX65_RS27305	COG2610	gluconate transmembrane transporter activity
CNX65_RS27325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNX65_RS27345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_RS27350	COG0640	Transcriptional regulator
CNX65_RS27420	COG5650	phosphatidylinositol metabolic process
CNX65_RS27445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_RS27450	COG0823	Involved in the tonB-independent uptake of proteins
CNX65_RS27450	COG1506	peptidase
CNX65_RS27450	COG4946	Tricorn protease homolog
CNX65_RS27460	COG1131	(ABC) transporter
CNX65_RS27490	COG0237	dephospho-CoA kinase activity
CNX65_RS27490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CNX65_RS27500	COG0539	negative regulation of cytoplasmic translation
CNX65_RS27505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_RS27520	COG1511	domain protein
CNX65_RS27525	COG1309	transcriptional regulator
CNX65_RS27540	COG0673	inositol 2-dehydrogenase activity
CNX65_RS27560	COG0410	ABC transporter
CNX65_RS27605	COG1832	CoA-binding protein
CNX65_RS27610	COG0251	oxidation-reduction process
CNX65_RS27625	COG1357	PFAM Pentapeptide repeats (8 copies)
CNX65_RS27630	COG0514	ATP-dependent DNA helicase (RecQ)
CNX65_RS27665	COG1937	Protein conserved in bacteria
CNX65_RS27685	COG1595	DNA-templated transcription, initiation
CNX65_RS27690	COG1408	metallophosphoesterase
CNX65_RS27700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CNX65_RS27715	COG0778	Nitroreductase
CNX65_RS27720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CNX65_RS27725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CNX65_RS27735	COG1566	PFAM secretion protein HlyD family protein
CNX65_RS27745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CNX65_RS27750	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS27760	COG0183	Belongs to the thiolase family
CNX65_RS27765	COG1250	3-hydroxyacyl-CoA dehydrogenase
CNX65_RS27765	COG1024	Enoyl-CoA hydratase
CNX65_RS27790	COG0577	efflux transmembrane transporter activity
CNX65_RS27790	COG1136	(ABC) transporter
CNX65_RS27795	COG0577	efflux transmembrane transporter activity
CNX65_RS27795	COG1136	(ABC) transporter
CNX65_RS27800	COG1672	PFAM Archaeal ATPase
CNX65_RS27800	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CNX65_RS27805	COG3629	intracellular signal transduction
CNX65_RS27805	COG3903	Transcriptional regulator
CNX65_RS27835	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CNX65_RS27865	COG1946	Acyl-CoA thioesterase
CNX65_RS27900	COG0067	glutamate synthase
CNX65_RS27900	COG0069	glutamate synthase activity
CNX65_RS27900	COG0070	glutamate synthase
CNX65_RS27905	COG1301	dicarboxylic acid transport
CNX65_RS27920	COG2205	protein histidine kinase activity
CNX65_RS27930	COG0745	RESPONSE REGULATOR receiver
CNX65_RS27935	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CNX65_RS27940	COG0159	tryptophan synthase activity
CNX65_RS27945	COG0133	tryptophan synthase activity
CNX65_RS27950	COG0134	indole-3-glycerol-phosphate synthase activity
CNX65_RS27960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNX65_RS27970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CNX65_RS27980	COG0107	imidazoleglycerol-phosphate synthase activity
CNX65_RS27985	COG3654	unkown
CNX65_RS28000	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CNX65_RS28005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CNX65_RS28015	COG3958	Transketolase
CNX65_RS28020	COG3959	Transketolase, thiamine diphosphate binding domain
CNX65_RS28030	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CNX65_RS28035	COG0131	Imidazoleglycerol-phosphate dehydratase
CNX65_RS28040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNX65_RS28045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CNX65_RS28055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNX65_RS28080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CNX65_RS28105	COG2814	Major facilitator Superfamily
CNX65_RS28125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNX65_RS28140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CNX65_RS28155	COG2814	Major facilitator Superfamily
CNX65_RS28165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CNX65_RS28175	COG3263	regulation of cellular component size
CNX65_RS28190	COG1872	DUF167
CNX65_RS28195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CNX65_RS28215	COG1799	cell septum assembly
CNX65_RS28230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CNX65_RS28235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CNX65_RS28240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CNX65_RS28245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CNX65_RS28260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CNX65_RS28265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNX65_RS28280	COG0768	penicillin binding
CNX65_RS28290	COG0275	rRNA processing
CNX65_RS28295	COG2001	Belongs to the MraZ family
CNX65_RS28300	COG0714	Associated with various cellular activities
CNX65_RS28340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_RS28345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNX65_RS28355	COG0174	glutamine synthetase
CNX65_RS28370	COG1192	Involved in chromosome partitioning
CNX65_RS28375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNX65_RS28380	COG0167	dihydroorotate dehydrogenase activity
CNX65_RS28390	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS28395	COG2233	PERMEase
CNX65_RS28405	COG1842	Phage shock protein A
CNX65_RS28410	COG1396	sequence-specific DNA binding
CNX65_RS28415	COG1546	Belongs to the CinA family
CNX65_RS28415	COG1058	Belongs to the CinA family
CNX65_RS28425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNX65_RS28430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CNX65_RS28455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CNX65_RS28460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNX65_RS28470	COG0515	serine threonine protein kinase
CNX65_RS28480	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CNX65_RS28495	COG1309	transcriptional regulator
CNX65_RS28525	COG0667	Aldo Keto reductase
CNX65_RS28530	COG3214	Protein conserved in bacteria
CNX65_RS28550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CNX65_RS28560	COG1185	polyribonucleotide nucleotidyltransferase activity
CNX65_RS28565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CNX65_RS28585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CNX65_RS28600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CNX65_RS28630	COG0779	Required for maturation of 30S ribosomal subunits
CNX65_RS28655	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS28680	COG0442	prolyl-tRNA aminoacylation
CNX65_RS28690	COG3022	response to hydroperoxide
CNX65_RS28700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNX65_RS28715	COG0513	Belongs to the DEAD box helicase family
CNX65_RS28720	COG1648	precorrin-2 dehydrogenase activity
CNX65_RS28720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CNX65_RS28770	COG0156	8-amino-7-oxononanoate synthase activity
CNX65_RS28785	COG1280	lysine exporter protein (LysE YggA)
CNX65_RS28800	COG0501	Belongs to the peptidase M48B family
CNX65_RS28810	COG0110	maltose O-acetyltransferase activity
CNX65_RS28815	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CNX65_RS28825	COG1752	Esterase of the alpha-beta hydrolase superfamily
CNX65_RS28830	COG0726	polysaccharide deacetylase
CNX65_RS28835	COG1881	PFAM PEBP family protein
CNX65_RS28845	COG2807	transmembrane transport
CNX65_RS28850	COG2186	Transcriptional regulator
CNX65_RS28865	COG1492	cobalamin metabolic process
CNX65_RS28890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CNX65_RS28900	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CNX65_RS28915	COG2197	response regulator
CNX65_RS28920	COG4585	Histidine kinase
CNX65_RS28925	COG1177	transmembrane transport
CNX65_RS28930	COG1176	ABC-type spermidine putrescine transport system, permease component I
CNX65_RS28940	COG3842	ATPase activity
CNX65_RS28950	COG0515	serine threonine protein kinase
CNX65_RS28960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CNX65_RS28970	COG0667	Aldo Keto reductase
CNX65_RS28990	COG0233	cytoplasmic translational termination
CNX65_RS28995	COG0528	UMP kinase activity
CNX65_RS29000	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CNX65_RS29005	COG0052	Belongs to the universal ribosomal protein uS2 family
CNX65_RS29015	COG1191	sigma factor activity
CNX65_RS29035	COG0792	nuclease activity
CNX65_RS29045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CNX65_RS29050	COG0681	Belongs to the peptidase S26 family
CNX65_RS29055	COG0681	Belongs to the peptidase S26 family
CNX65_RS29060	COG0335	large ribosomal subunit rRNA binding
CNX65_RS29065	COG0336	Belongs to the RNA methyltransferase TrmD family
CNX65_RS29080	COG0228	four-way junction DNA binding
CNX65_RS29085	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CNX65_RS29120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CNX65_RS29140	COG4266	Belongs to the allantoicase family
CNX65_RS29145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNX65_RS29170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CNX65_RS29175	COG1414	Transcriptional regulator
CNX65_RS29190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CNX65_RS29205	COG0454	-acetyltransferase
CNX65_RS29205	COG0456	acetyltransferase
CNX65_RS29240	COG1254	Belongs to the acylphosphatase family
CNX65_RS29245	COG2340	Cysteine-rich secretory protein family
CNX65_RS29275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNX65_RS29285	COG0571	ribonuclease III activity
CNX65_RS29290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CNX65_RS29305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CNX65_RS29310	COG0742	ribosomal rna small subunit methyltransferase
CNX65_RS29365	COG1461	Dihydroxyacetone kinase
CNX65_RS29370	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CNX65_RS29390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CNX65_RS29395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CNX65_RS29420	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNX65_RS29435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_RS29450	COG3344	reverse transcriptase
CNX65_RS29485	COG0626	cystathionine gamma-synthase activity
CNX65_RS29490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CNX65_RS29500	COG1920	GTP binding
CNX65_RS29515	COG0406	alpha-ribazole phosphatase activity
CNX65_RS29515	COG0494	nUDIX hydrolase
CNX65_RS29525	COG0066	3-isopropylmalate dehydratase activity
CNX65_RS29530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CNX65_RS29555	COG1011	Hydrolase
CNX65_RS29560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CNX65_RS29570	COG0179	Fumarylacetoacetate (FAA) hydrolase
CNX65_RS29580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CNX65_RS29585	COG0473	3-isopropylmalate dehydrogenase activity
CNX65_RS29590	COG1404	Belongs to the peptidase S8 family
CNX65_RS29605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CNX65_RS29610	COG0440	acetolactate synthase activity
CNX65_RS29630	COG0129	dihydroxy-acid dehydratase activity
CNX65_RS29635	COG2259	Doxx family
CNX65_RS29680	COG0154	amidase activity
CNX65_RS29685	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CNX65_RS29700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNX65_RS29715	COG2855	membrane
CNX65_RS29750	COG0482	sulfurtransferase activity
CNX65_RS29775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CNX65_RS29785	COG1307	EDD domain protein, DegV family
CNX65_RS29800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CNX65_RS29830	COG0110	maltose O-acetyltransferase activity
CNX65_RS29855	COG1119	ATPase activity
CNX65_RS29880	COG0058	SHG alpha-glucan phosphorylase activity
CNX65_RS29885	COG0366	Alpha amylase catalytic
CNX65_RS29890	COG0366	Alpha amylase catalytic
CNX65_RS29905	COG2321	neutral zinc metallopeptidase
CNX65_RS29930	COG1846	Transcriptional regulator
CNX65_RS29940	COG2409	Drug exporters of the RND superfamily
CNX65_RS29945	COG1131	(ABC) transporter
CNX65_RS29960	COG1609	Transcriptional regulator
CNX65_RS29975	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_RS29980	COG1879	ABC-type sugar transport system periplasmic component
CNX65_RS29990	COG0596	Alpha beta hydrolase
CNX65_RS30030	COG0183	Belongs to the thiolase family
CNX65_RS30035	COG0346	lactoylglutathione lyase activity
CNX65_RS30070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNX65_RS30080	COG2376	Dihydroxyacetone kinase
CNX65_RS30135	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CNX65_RS30150	COG1024	Enoyl-CoA hydratase
CNX65_RS30190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CNX65_RS30195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CNX65_RS30200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CNX65_RS30205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CNX65_RS30210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CNX65_RS30215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CNX65_RS30220	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CNX65_RS30225	COG0356	it plays a direct role in the translocation of protons across the membrane
CNX65_RS30240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNX65_RS30255	COG2890	protein-(glutamine-N5) methyltransferase activity
CNX65_RS30270	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CNX65_RS30275	COG0254	rRNA binding
CNX65_RS30285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CNX65_RS30290	COG0083	homoserine kinase activity
CNX65_RS30295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CNX65_RS30300	COG0460	homoserine dehydrogenase
CNX65_RS30305	COG0019	diaminopimelate decarboxylase activity
CNX65_RS30310	COG0018	arginyl-trna synthetase
CNX65_RS30325	COG3537	Alpha-1,2-mannosidase
CNX65_RS30360	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNX65_RS30365	COG3903	Transcriptional regulator
CNX65_RS30365	COG3629	intracellular signal transduction
CNX65_RS30370	COG0596	Alpha beta hydrolase
CNX65_RS30410	COG1162	GTPase activity
CNX65_RS30420	COG0667	Aldo Keto reductase
CNX65_RS30425	COG1609	Transcriptional regulator
CNX65_RS30455	COG0444	Belongs to the ABC transporter superfamily
CNX65_RS30460	COG0601	transmembrane transport
CNX65_RS30465	COG4166	transmembrane transport
CNX65_RS30480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNX65_RS30490	COG2890	protein-(glutamine-N5) methyltransferase activity
CNX65_RS30495	COG4941	Belongs to the sigma-70 factor family
CNX65_RS30500	COG3795	YCII-related domain
CNX65_RS30530	COG0640	Transcriptional regulator
CNX65_RS30540	COG1940	carbohydrate kinase activity
CNX65_RS30555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CNX65_RS30560	COG0745	RESPONSE REGULATOR receiver
CNX65_RS30565	COG2205	protein histidine kinase activity
CNX65_RS30585	COG1404	Belongs to the peptidase S8 family
CNX65_RS30595	COG0583	DNA-binding transcription factor activity
CNX65_RS30625	COG3629	intracellular signal transduction
CNX65_RS30625	COG3903	Transcriptional regulator
CNX65_RS30640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNX65_RS30645	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS30650	COG1024	Enoyl-CoA hydratase
CNX65_RS30655	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS30665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNX65_RS30705	COG3469	chitinase activity
CNX65_RS30710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNX65_RS30720	COG0673	inositol 2-dehydrogenase activity
CNX65_RS30740	COG0386	Belongs to the glutathione peroxidase family
CNX65_RS30745	COG1760	l-serine dehydratase
CNX65_RS30750	COG0509	glycine decarboxylation via glycine cleavage system
CNX65_RS30755	COG0686	Belongs to the AlaDH PNT family
CNX65_RS30780	COG1132	(ABC) transporter
CNX65_RS30785	COG0567	Dehydrogenase, E1 component
CNX65_RS30785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_RS30800	COG0667	Aldo Keto reductase
CNX65_RS30815	COG3903	Transcriptional regulator
CNX65_RS30815	COG3629	intracellular signal transduction
CNX65_RS30830	COG1228	amidohydrolase
CNX65_RS30845	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CNX65_RS30850	COG2986	histidine ammonia-lyase
CNX65_RS30870	COG1174	glycine betaine transport
CNX65_RS30915	COG5001	Diguanylate cyclase
CNX65_RS30925	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CNX65_RS30945	COG0406	alpha-ribazole phosphatase activity
CNX65_RS30970	COG1597	lipid kinase activity
CNX65_RS30990	COG5662	AntiSigma factor
CNX65_RS30995	COG1595	DNA-templated transcription, initiation
CNX65_RS31000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CNX65_RS31010	COG2135	peptidase activity
CNX65_RS31015	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CNX65_RS31020	COG1162	GTPase activity
CNX65_RS31045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNX65_RS31050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNX65_RS31060	COG0653	protein targeting
CNX65_RS31065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CNX65_RS31070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CNX65_RS31075	COG5401	PFAM Sporulation and spore germination
CNX65_RS31080	COG5002	protein histidine kinase activity
CNX65_RS31085	COG0745	RESPONSE REGULATOR receiver
CNX65_RS31100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CNX65_RS31105	COG0531	amino acid
CNX65_RS31115	COG1482	cell wall glycoprotein biosynthetic process
CNX65_RS31155	COG1994	Peptidase M50
CNX65_RS31160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CNX65_RS31165	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CNX65_RS31165	COG0778	Nitroreductase
CNX65_RS31180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CNX65_RS31200	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS31220	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS31235	COG1316	TRANSCRIPTIONal
CNX65_RS31240	COG1316	TRANSCRIPTIONal
CNX65_RS31250	COG2259	Doxx family
CNX65_RS31280	COG3842	ATPase activity
CNX65_RS31285	COG2186	Transcriptional regulator
CNX65_RS31330	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_RS31335	COG0745	RESPONSE REGULATOR receiver
CNX65_RS31340	COG2205	protein histidine kinase activity
CNX65_RS31380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNX65_RS31395	COG0424	maF-like protein
CNX65_RS31400	COG1301	dicarboxylic acid transport
CNX65_RS31410	COG4770	biotin carboxylase activity
CNX65_RS31455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CNX65_RS31460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CNX65_RS31465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CNX65_RS31475	COG1473	amidohydrolase
CNX65_RS31475	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CNX65_RS31505	COG0515	serine threonine protein kinase
CNX65_RS31515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNX65_RS31535	COG3654	unkown
CNX65_RS31600	COG3883	PFAM NLP P60 protein
CNX65_RS31600	COG0791	NLP P60 protein
CNX65_RS31620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CNX65_RS31645	COG1079	Belongs to the binding-protein-dependent transport system permease family
CNX65_RS31650	COG4603	Belongs to the binding-protein-dependent transport system permease family
CNX65_RS31655	COG3845	ABC transporter
CNX65_RS31660	COG1744	ABC transporter substrate-binding protein PnrA-like
CNX65_RS31705	COG2009	succinate dehydrogenase
CNX65_RS31720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CNX65_RS31725	COG1686	Belongs to the peptidase S11 family
CNX65_RS31740	COG1295	ribonuclease BN
CNX65_RS31745	COG0180	Tryptophanyl-tRNA synthetase
CNX65_RS31755	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CNX65_RS31770	COG0708	Exodeoxyribonuclease III
CNX65_RS31805	COG0484	heat shock protein binding
CNX65_RS31830	COG4555	ABC transporter
CNX65_RS31855	COG0039	L-malate dehydrogenase activity
CNX65_RS31885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CNX65_RS31935	COG0045	succinate-CoA ligase (ADP-forming) activity
CNX65_RS31990	COG2815	serine threonine protein kinase
CNX65_RS31990	COG0515	serine threonine protein kinase
CNX65_RS31995	COG0515	serine threonine protein kinase
CNX65_RS32000	COG0583	DNA-binding transcription factor activity
CNX65_RS32005	COG0697	spore germination
CNX65_RS32035	COG0519	Catalyzes the synthesis of GMP from XMP
CNX65_RS32035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CNX65_RS32045	COG1012	belongs to the aldehyde dehydrogenase family
CNX65_RS32060	COG0516	GMP reductase activity
CNX65_RS32105	COG0459	protein refolding
CNX65_RS32110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNX65_RS32120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CNX65_RS32125	COG0456	acetyltransferase
CNX65_RS32140	COG3118	belongs to the thioredoxin family
CNX65_RS32145	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS32150	COG0825	malonyl-CoA metabolic process
CNX65_RS32150	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CNX65_RS32175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CNX65_RS32185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CNX65_RS32210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNX65_RS32215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CNX65_RS32220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CNX65_RS32235	COG0443	Heat shock 70 kDa protein
CNX65_RS32245	COG1674	ftsk spoiiie
CNX65_RS32255	COG1404	Belongs to the peptidase S8 family
CNX65_RS32290	COG0101	tRNA pseudouridine synthase activity
CNX65_RS32295	COG0203	ribosomal protein L17
CNX65_RS32300	COG0202	RNA polymerase activity
CNX65_RS32305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CNX65_RS32310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CNX65_RS32320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CNX65_RS32325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CNX65_RS32345	COG0563	adenylate kinase activity
CNX65_RS32365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CNX65_RS32370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CNX65_RS32375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CNX65_RS32380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CNX65_RS32385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNX65_RS32390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CNX65_RS32395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CNX65_RS32400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CNX65_RS32405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CNX65_RS32420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CNX65_RS32425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CNX65_RS32430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CNX65_RS32435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CNX65_RS32440	COG0089	rRNA binding
CNX65_RS32445	COG0088	Forms part of the polypeptide exit tunnel
CNX65_RS32450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CNX65_RS32455	COG0051	transcription antitermination factor activity, RNA binding
CNX65_RS32460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNX65_RS32465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNX65_RS32470	COG0049	tRNA binding
CNX65_RS32475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CNX65_RS32515	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNX65_RS32520	COG0085	RNA polymerase activity
CNX65_RS32545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CNX65_RS32560	COG0222	ribosome binding
CNX65_RS32575	COG0081	regulation of translation
CNX65_RS32580	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CNX65_RS32590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNX65_RS32600	COG0436	Aminotransferase
CNX65_RS32615	COG2030	dehydratase
CNX65_RS32620	COG2030	dehydratase
CNX65_RS32625	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CNX65_RS32790	COG1666	GTP binding
CNX65_RS32795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CNX65_RS32805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_RS32810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_RS32810	COG0649	NAD binding
CNX65_RS32815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_RS32825	COG1834	amidinotransferase
CNX65_RS32830	COG1522	sequence-specific DNA binding
CNX65_RS32840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CNX65_RS32840	COG0674	pyruvate-flavodoxin oxidoreductase activity
CNX65_RS32845	COG1013	pyruvate-flavodoxin oxidoreductase activity
CNX65_RS32860	COG0142	geranyltranstransferase activity
CNX65_RS32865	COG1007	ATP synthesis coupled electron transport
CNX65_RS32880	COG0713	ATP synthesis coupled electron transport
CNX65_RS32885	COG0839	Belongs to the complex I subunit 6 family
CNX65_RS32890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_RS32895	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CNX65_RS32900	COG1034	ATP synthesis coupled electron transport
CNX65_RS32905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CNX65_RS32915	COG0649	NAD binding
CNX65_RS32920	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_RS32925	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CNX65_RS32940	COG2226	methyltransferase
CNX65_RS32945	COG0483	inositol monophosphate 1-phosphatase activity
CNX65_RS32955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CNX65_RS32960	COG2151	metal-sulfur cluster biosynthetic enzyme
CNX65_RS32965	COG3396	Phenylacetate-CoA oxygenase
CNX65_RS32970	COG3460	Phenylacetate-CoA oxygenase
CNX65_RS32975	COG3396	Phenylacetate-CoA oxygenase
CNX65_RS33025	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CNX65_RS33075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CNX65_RS33080	COG1333	cytochrome c biogenesis protein
CNX65_RS33085	COG0785	Cytochrome C biogenesis protein
CNX65_RS33105	COG0406	alpha-ribazole phosphatase activity
CNX65_RS33110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CNX65_RS33150	COG0113	porphobilinogen synthase activity
CNX65_RS33160	COG0181	hydroxymethylbilane synthase activity
CNX65_RS33165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CNX65_RS33170	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CNX65_RS33190	COG0318	PFAM AMP-dependent synthetase and ligase
CNX65_RS33235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CNX65_RS33270	COG5002	protein histidine kinase activity
CNX65_RS33275	COG0667	Aldo Keto reductase
CNX65_RS33285	COG0588	phosphoglycerate mutase activity
CNX65_RS33305	COG0438	transferase activity, transferring glycosyl groups
CNX65_RS33325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CNX65_RS33355	COG3226	Transcriptional regulator
CNX65_RS33370	COG0693	protein deglycase activity
CNX65_RS33400	COG2733	membrane
CNX65_RS33430	COG1136	(ABC) transporter
CNX65_RS33465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_RS33470	COG2364	Membrane
CNX65_RS33530	COG1278	Cold shock
CNX65_RS33535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_RS33550	COG2255	four-way junction helicase activity
CNX65_RS33695	COG1316	TRANSCRIPTIONal
CNX65_RS33715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CNX65_RS33735	COG0456	acetyltransferase
CNX65_RS33740	COG0745	RESPONSE REGULATOR receiver
CNX65_RS33765	COG2897	thiosulfate sulfurtransferase activity
CNX65_RS33775	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CNX65_RS33780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CNX65_RS33795	COG0735	belongs to the Fur family
CNX65_RS33815	COG2271	Major facilitator Superfamily
CNX65_RS33840	COG3962	Belongs to the TPP enzyme family
CNX65_RS33845	COG3718	enzyme involved in inositol metabolism
CNX65_RS33860	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNX65_RS33870	COG1082	Xylose isomerase domain protein TIM barrel
CNX65_RS33880	COG1609	Transcriptional regulator
CNX65_RS33885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CNX65_RS33900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CNX65_RS33960	COG5001	Diguanylate cyclase
CNX65_RS33960	COG3300	MHYT domain
CNX65_RS33985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNX65_RS33990	COG0047	phosphoribosylformylglycinamidine synthase activity
CNX65_RS33995	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNX65_RS34020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CNX65_RS34030	COG0765	amino acid transport
CNX65_RS34045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNX65_RS34055	COG1595	DNA-templated transcription, initiation
CNX65_RS34070	COG1595	DNA-templated transcription, initiation
CNX65_RS34080	COG1011	Hydrolase
CNX65_RS34085	COG0436	Aminotransferase
CNX65_RS34125	COG0584	glycerophosphoryl diester phosphodiesterase
CNX65_RS34135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CNX65_RS34165	COG4129	membrane
CNX65_RS34185	COG0667	Aldo Keto reductase
CNX65_RS34190	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS34200	COG1595	DNA-templated transcription, initiation
CNX65_RS34225	COG0277	FAD linked oxidase domain protein
CNX65_RS34230	COG0586	Pfam SNARE associated Golgi protein
CNX65_RS34235	COG1072	(Pantothenic acid kinase))
CNX65_RS34240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNX65_RS34270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CNX65_RS34295	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS34305	COG0542	response to heat
CNX65_RS34315	COG2871	sodium ion transport
CNX65_RS34320	COG0789	Transcriptional regulator
CNX65_RS34325	COG0484	heat shock protein binding
CNX65_RS34330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CNX65_RS34335	COG0443	Heat shock 70 kDa protein
CNX65_RS34355	COG2181	nitrate reductase activity
CNX65_RS34355	COG0247	lactate metabolic process
CNX65_RS34360	COG1950	PFAM Membrane protein of
CNX65_RS34385	COG0717	Belongs to the dCTP deaminase family
CNX65_RS34405	COG2197	response regulator
CNX65_RS34410	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS34425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNX65_RS34435	COG3311	Transcriptional regulator
CNX65_RS34440	COG1569	PIN domain
CNX65_RS34465	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS34475	COG1960	acyl-CoA dehydrogenase activity
CNX65_RS34485	COG1309	transcriptional regulator
CNX65_RS34490	COG0789	Transcriptional regulator
CNX65_RS34495	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNX65_RS34500	COG0022	dehydrogenase e1 component
CNX65_RS34510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNX65_RS34520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNX65_RS34525	COG0765	amino acid transport
CNX65_RS34560	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CNX65_RS34590	COG1940	carbohydrate kinase activity
CNX65_RS34615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CNX65_RS34630	COG4585	Histidine kinase
CNX65_RS34635	COG2197	response regulator
CNX65_RS34640	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS34650	COG0561	phosphatase activity
CNX65_RS34665	COG4585	Histidine kinase
CNX65_RS34670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CNX65_RS34690	COG1131	(ABC) transporter
CNX65_RS34705	COG0402	S-adenosylhomocysteine deaminase activity
CNX65_RS34710	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS34725	COG2814	Major facilitator Superfamily
CNX65_RS34730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNX65_RS34735	COG1028	Short-chain dehydrogenase reductase Sdr
CNX65_RS34755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNX65_RS34780	COG0360	Binds together with S18 to 16S ribosomal RNA
CNX65_RS34785	COG0629	single-stranded DNA binding
CNX65_RS34790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CNX65_RS34795	COG0359	binds to the 23S rRNA
CNX65_RS34800	COG0305	Participates in initiation and elongation during chromosome replication
CNX65_RS34890	COG0702	epimerase
CNX65_RS34895	COG1063	alcohol dehydrogenase
CNX65_RS34905	COG0583	DNA-binding transcription factor activity
CNX65_RS34915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CNX65_RS34920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNX65_RS34940	COG0495	leucyl-tRNA aminoacylation
CNX65_RS34960	COG2197	response regulator
CNX65_RS34965	COG0617	tRNA 3'-terminal CCA addition
CNX65_RS34985	COG0515	serine threonine protein kinase
CNX65_RS34990	COG1595	DNA-templated transcription, initiation
CNX65_RS35005	COG0492	ferredoxin-NADP+ reductase activity
CNX65_RS35005	COG3118	belongs to the thioredoxin family
CNX65_RS35010	COG3409	Peptidoglycan-binding domain 1 protein
CNX65_RS35010	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNX65_RS35030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNX65_RS35035	COG1181	Belongs to the D-alanine--D-alanine ligase family
CNX65_RS35045	COG1192	Involved in chromosome partitioning
CNX65_RS35050	COG0357	Ribosomal RNA small subunit methyltransferase G
CNX65_RS35065	COG0706	membrane insertase activity
CNX65_RS35070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CNX65_RS35075	COG0594	ribonuclease P activity
CNX65_RS35080	COG0230	Belongs to the bacterial ribosomal protein bL34 family